Analysis Type: PANTHER Overrepresentation Test (Released 20210224) Annotation Version and Release Date: GO Ontology database DOI: 10.5281/zenodo.4735677 Released 2021-05-01 Analyzed List: ery_global.txt (Mus musculus) There are duplicate IDs in the file. The unique set of IDs will be used. Reference List: ery_reference.txt (Mus musculus) Test Type: FISHER Correction: FDR GO biological process complete ery_reference.txt - REFLIST (14797) ery_global.txt (1463) ery_global.txt (expected) ery_global.txt (over/under) ery_global.txt (fold Enrichment) ery_global.txt (raw P-value) ery_global.txt (FDR) negative regulation of T cell anergy (GO:0002668) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of T cell tolerance induction (GO:0002665) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of macrophage antigen processing and presentation (GO:0002617) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of macrophage antigen processing and presentation (GO:0002616) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of dendritic cell antigen processing and presentation (GO:0002605) 3 3 .30 + 10.11 1.18E-02 2.46E-01 positive regulation of hydrogen peroxide catabolic process (GO:1903285) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of glutathione peroxidase activity (GO:1903284) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of glutathione peroxidase activity (GO:1903282) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of sodium ion export across plasma membrane (GO:1903277) 1 1 .10 + 10.11 1.72E-01 1.00E00 hexitol catabolic process (GO:0019407) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of the force of heart contraction by epinephrine (GO:0003059) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of choline O-acetyltransferase activity (GO:1902771) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of choline O-acetyltransferase activity (GO:1902769) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of toll-like receptor 13 signaling pathway (GO:0034181) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of toll-like receptor 13 signaling pathway (GO:0034179) 1 1 .10 + 10.11 1.72E-01 1.00E00 toll-like receptor 13 signaling pathway (GO:0034178) 1 1 .10 + 10.11 1.72E-01 1.00E00 response to lipid hydroperoxide (GO:0006982) 1 1 .10 + 10.11 1.72E-01 1.00E00 cell gliding (GO:0071976) 1 1 .10 + 10.11 1.72E-01 1.00E00 extracellular exosome assembly (GO:0071971) 1 1 .10 + 10.11 1.72E-01 1.00E00 induction by virus of host cell-cell fusion (GO:0006948) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of erythrocyte aggregation (GO:0034120) 1 1 .10 + 10.11 1.72E-01 1.00E00 dichloromethane metabolic process (GO:0018900) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of eosinophil differentiation (GO:0045645) 2 2 .20 + 10.11 4.29E-02 5.61E-01 regulation of eosinophil differentiation (GO:0045643) 2 2 .20 + 10.11 4.29E-02 5.60E-01 pyridine nucleotide salvage (GO:0019365) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation (GO:1903125) 1 1 .10 + 10.11 1.72E-01 1.00E00 thorax and anterior abdomen determination (GO:0007356) 1 1 .10 + 10.11 1.72E-01 1.00E00 amylopectin metabolic process (GO:2000896) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of progesterone secretion (GO:2000872) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of estradiol secretion (GO:2000866) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of corticosterone secretion (GO:2000854) 1 1 .10 + 10.11 1.72E-01 1.00E00 coronal suture morphogenesis (GO:0060365) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of leucine import (GO:0060358) 2 2 .20 + 10.11 4.29E-02 5.60E-01 regulation of leucine import (GO:0060357) 2 2 .20 + 10.11 4.29E-02 5.59E-01 spleen trabecula formation (GO:0060345) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of glomerular metanephric mesangial cell proliferation (GO:0072303) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of metanephric glomerular mesangial cell proliferation (GO:0072301) 1 1 .10 + 10.11 1.72E-01 1.00E00 elastin catabolic process (GO:0060309) 2 2 .20 + 10.11 4.29E-02 5.59E-01 regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway (GO:0071877) 1 1 .10 + 10.11 1.72E-01 1.00E00 cellular response to norepinephrine stimulus (GO:0071874) 1 1 .10 + 10.11 1.72E-01 1.00E00 response to norepinephrine (GO:0071873) 1 1 .10 + 10.11 1.72E-01 1.00E00 plasmacytoid dendritic cell antigen processing and presentation (GO:0002470) 1 1 .10 + 10.11 1.72E-01 1.00E00 apoptotic process in bone marrow cell (GO:0071839) 1 1 .10 + 10.11 1.72E-01 1.00E00 type II hypersensitivity (GO:0002445) 3 3 .30 + 10.11 1.18E-02 2.46E-01 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis (GO:0002433) 2 2 .20 + 10.11 4.29E-02 5.58E-01 amylopectin biosynthetic process (GO:0010021) 1 1 .10 + 10.11 1.72E-01 1.00E00 protein galactosylation at cell surface (GO:0033580) 1 1 .10 + 10.11 1.72E-01 1.00E00 protein glycosylation at cell surface (GO:0033575) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of phosphatidylcholine biosynthetic process (GO:2001246) 1 1 .10 + 10.11 1.72E-01 1.00E00 glycine betaine biosynthetic process from choline (GO:0019285) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of acetylcholine-gated cation channel activity (GO:1903048) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of activation of membrane attack complex (GO:0001970) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of oocyte development (GO:0060283) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of nephron tubule epithelial cell differentiation (GO:2000768) 1 1 .10 + 10.11 1.72E-01 1.00E00 metanephric proximal tubule development (GO:0072237) 1 1 .10 + 10.11 1.72E-01 1.00E00 metanephric proximal convoluted tubule segment 2 development (GO:0072232) 1 1 .10 + 10.11 1.72E-01 1.00E00 metanephric proximal straight tubule development (GO:0072230) 1 1 .10 + 10.11 1.72E-01 1.00E00 metanephric proximal convoluted tubule development (GO:0072229) 1 1 .10 + 10.11 1.72E-01 1.00E00 metanephric descending thin limb development (GO:0072220) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of hippocampal neuron apoptotic process (GO:0110090) 2 2 .20 + 10.11 4.29E-02 5.58E-01 positive regulation of catalase activity (GO:1902553) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of catalase activity (GO:1902551) 1 1 .10 + 10.11 1.72E-01 1.00E00 uroporphyrinogen III biosynthetic process (GO:0006780) 1 1 .10 + 10.11 1.72E-01 1.00E00 estrogen catabolic process (GO:0006711) 1 1 .10 + 10.11 1.72E-01 1.00E00 sodium-independent icosanoid transport (GO:0071718) 1 1 .10 + 10.11 1.72E-01 1.00E00 follicular B cell differentiation (GO:0002316) 3 3 .30 + 10.11 1.18E-02 2.45E-01 negative regulation of complement activation, lectin pathway (GO:0001869) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of complement activation, lectin pathway (GO:0001868) 1 1 .10 + 10.11 1.72E-01 1.00E00 meiotic recombination nodule assembly (GO:0007146) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of dendritic cell apoptotic process (GO:2000669) 3 3 .30 + 10.11 1.18E-02 2.45E-01 positive regulation of interleukin-1-mediated signaling pathway (GO:2000661) 1 1 .10 + 10.11 1.72E-01 1.00E00 renal interstitial fibroblast development (GO:0072141) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of type I hypersensitivity (GO:0001811) 1 1 .10 + 10.11 1.72E-01 1.00E00 glomerular parietal epithelial cell differentiation (GO:0072139) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of adenosine receptor signaling pathway (GO:0060168) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of dopamine receptor signaling pathway (GO:0060160) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of IP-10 production (GO:0071659) 1 1 .10 + 10.11 1.72E-01 1.00E00 mastication (GO:0071626) 1 1 .10 + 10.11 1.72E-01 1.00E00 stimulatory killer cell immunoglobulin-like receptor signaling pathway (GO:0002222) 1 1 .10 + 10.11 1.72E-01 1.00E00 MHC class II biosynthetic process (GO:0045342) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of endothelial cell chemotaxis (GO:2001027) 2 2 .20 + 10.11 4.29E-02 5.57E-01 type IIa hypersensitivity (GO:0001794) 3 3 .30 + 10.11 1.18E-02 2.45E-01 antibody-dependent cellular cytotoxicity (GO:0001788) 3 3 .30 + 10.11 1.18E-02 2.44E-01 male meiosis sister chromatid cohesion (GO:0007065) 1 1 .10 + 10.11 1.72E-01 1.00E00 kidney interstitial fibroblast differentiation (GO:0072071) 1 1 .10 + 10.11 1.72E-01 1.00E00 urokinase plasminogen activator signaling pathway (GO:0038195) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of CD8-positive, alpha-beta T cell proliferation (GO:2000565) 1 1 .10 + 10.11 1.72E-01 1.00E00 proximal convoluted tubule segment 2 development (GO:0072032) 1 1 .10 + 10.11 1.72E-01 1.00E00 Spemann organizer formation (GO:0060061) 1 1 .10 + 10.11 1.72E-01 1.00E00 complement component C5a signaling pathway (GO:0038178) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of protein geranylgeranylation (GO:2000541) 1 1 .10 + 10.11 1.72E-01 1.00E00 descending thin limb development (GO:0072022) 1 1 .10 + 10.11 1.72E-01 1.00E00 proximal straight tubule development (GO:0072020) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of protein geranylgeranylation (GO:2000539) 1 1 .10 + 10.11 1.72E-01 1.00E00 epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade (GO:0038168) 1 1 .10 + 10.11 1.72E-01 1.00E00 epidermal growth factor receptor signaling pathway via positive regulation of NF-kappaB transcription factor activity (GO:0038167) 1 1 .10 + 10.11 1.72E-01 1.00E00 proximal convoluted tubule development (GO:0072019) 1 1 .10 + 10.11 1.72E-01 1.00E00 VEGF-activated neuropilin signaling pathway involved in axon guidance (GO:1902378) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of myeloid dendritic cell chemotaxis (GO:2000529) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of myeloid dendritic cell chemotaxis (GO:2000527) 1 1 .10 + 10.11 1.72E-01 1.00E00 melanocyte apoptotic process (GO:1902362) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of cellular pH reduction (GO:0032848) 1 1 .10 + 10.11 1.72E-01 1.00E00 acetylcholine catabolic process (GO:0006581) 1 1 .10 + 10.11 1.72E-01 1.00E00 interleukin-8-mediated signaling pathway (GO:0038112) 1 1 .10 + 10.11 1.72E-01 1.00E00 detoxification of cadmium ion (GO:0071585) 2 2 .20 + 10.11 4.29E-02 5.57E-01 negative regulation of zinc ion transmembrane import (GO:0071584) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of zinc ion transmembrane import (GO:0071581) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of copper ion transmembrane transport (GO:1902311) 1 1 .10 + 10.11 1.72E-01 1.00E00 glutamate catabolic process via 2-oxoglutarate (GO:0006539) 1 1 .10 + 10.11 1.72E-01 1.00E00 hypochlorous acid biosynthetic process (GO:0002149) 1 1 .10 + 10.11 1.72E-01 1.00E00 hypochlorous acid metabolic process (GO:0002148) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of catecholamine uptake involved in synaptic transmission (GO:0051945) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA (GO:1901835) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of deadenylation-independent decapping of nuclear-transcribed mRNA (GO:1901834) 1 1 .10 + 10.11 1.72E-01 1.00E00 histamine biosynthetic process (GO:0001694) 2 2 .20 + 10.11 4.29E-02 5.56E-01 carbohydrate export (GO:0033231) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of peroxidase activity (GO:2000470) 2 2 .20 + 10.11 4.29E-02 5.56E-01 Fc-gamma receptor signaling pathway involved in phagocytosis (GO:0038096) 2 2 .20 + 10.11 4.29E-02 5.55E-01 positive regulation of astrocyte chemotaxis (GO:2000464) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of apoptotic cell clearance (GO:2000426) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of fibronectin-dependent thymocyte migration (GO:2000415) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of fibronectin-dependent thymocyte migration (GO:2000413) 1 1 .10 + 10.11 1.72E-01 1.00E00 insulin receptor recycling (GO:0038020) 1 1 .10 + 10.11 1.72E-01 1.00E00 inhibition of neuroepithelial cell differentiation (GO:0002085) 1 1 .10 + 10.11 1.72E-01 1.00E00 valyl-tRNA aminoacylation (GO:0006438) 2 2 .20 + 10.11 4.29E-02 5.55E-01 cellular response to lipid hydroperoxide (GO:0071449) 1 1 .10 + 10.11 1.72E-01 1.00E00 myofibroblast contraction (GO:1990764) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of microglia differentiation (GO:0014008) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of microglia differentiation (GO:0014006) 1 1 .10 + 10.11 1.72E-01 1.00E00 inhibitory G protein-coupled receptor phosphorylation (GO:0002030) 1 1 .10 + 10.11 1.72E-01 1.00E00 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure (GO:0002025) 1 1 .10 + 10.11 1.72E-01 1.00E00 cellular response to oleic acid (GO:0071400) 1 1 .10 + 10.11 1.72E-01 1.00E00 sucrose biosynthetic process (GO:0005986) 1 1 .10 + 10.11 1.72E-01 1.00E00 sucrose metabolic process (GO:0005985) 1 1 .10 + 10.11 1.72E-01 1.00E00 integrin biosynthetic process (GO:0045112) 1 1 .10 + 10.11 1.72E-01 1.00E00 lactosylceramide biosynthetic process (GO:0001572) 1 1 .10 + 10.11 1.72E-01 1.00E00 neutrophil-mediated killing of fungus (GO:0070947) 2 2 .20 + 10.11 4.29E-02 5.54E-01 negative regulation of thymocyte aggregation (GO:2000399) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of thymocyte aggregation (GO:2000398) 1 1 .10 + 10.11 1.72E-01 1.00E00 transcription elongation from mitochondrial promoter (GO:0006392) 1 1 .10 + 10.11 1.72E-01 1.00E00 interleukin-3 production (GO:0032632) 1 1 .10 + 10.11 1.72E-01 1.00E00 cellular response to sucrose stimulus (GO:0071329) 1 1 .10 + 10.11 1.72E-01 1.00E00 cellular response to disaccharide stimulus (GO:0071324) 1 1 .10 + 10.11 1.72E-01 1.00E00 cellular response to vitamin K (GO:0071307) 2 2 .20 + 10.11 4.29E-02 5.54E-01 negative regulation of hydrogen peroxide catabolic process (GO:2000296) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of hydrogen peroxide catabolic process (GO:2000295) 2 2 .20 + 10.11 4.29E-02 5.53E-01 oncogene-induced cell senescence (GO:0090402) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of actin cytoskeleton reorganization (GO:2000250) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of pancreatic stellate cell proliferation (GO:2000230) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of lateral motor column neuron migration (GO:1902078) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of lateral motor column neuron migration (GO:1902076) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of pancreatic A cell differentiation (GO:2000227) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of pancreatic A cell differentiation (GO:2000226) 1 1 .10 + 10.11 1.72E-01 1.00E00 protein deamination (GO:0018277) 1 1 .10 + 10.11 1.72E-01 1.00E00 protein delipidation (GO:0051697) 1 1 .10 + 10.11 1.72E-01 1.00E00 establishment of ER localization (GO:0051686) 1 1 .10 + 10.11 1.72E-01 1.00E00 peptidyl-serine trans-autophosphorylation (GO:1990579) 1 1 .10 + 10.11 1.72E-01 1.00E00 cellular response to chromate (GO:0071247) 1 1 .10 + 10.11 1.72E-01 1.00E00 cellular response to folic acid (GO:0071231) 1 1 .10 + 10.11 1.72E-01 1.00E00 mitochondrial alpha-ketoglutarate transmembrane transport (GO:1990550) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of response to calcium ion (GO:1905945) 1 1 .10 + 10.11 1.72E-01 1.00E00 mitochondrial NAD transmembrane transport (GO:1990549) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of cell fate determination (GO:1905934) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of cell fate determination (GO:1905933) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of norepinephrine uptake (GO:0051622) 1 1 .10 + 10.11 1.72E-01 1.00E00 response to fenofibrate (GO:1901557) 1 1 .10 + 10.11 1.72E-01 1.00E00 ether catabolic process (GO:1901502) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process (GO:0140194) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process (GO:0140193) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of female gonad development (GO:2000196) 1 1 .10 + 10.11 1.72E-01 1.00E00 detection of molecule of fungal origin (GO:0032491) 1 1 .10 + 10.11 1.72E-01 1.00E00 peptidyl-pyrromethane cofactor linkage (GO:0018160) 1 1 .10 + 10.11 1.72E-01 1.00E00 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine (GO:0018153) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of cellular response to tunicamycin (GO:1905896) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of cellular response to tunicamycin (GO:1905895) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of cellular response to tunicamycin (GO:1905894) 2 2 .20 + 10.11 4.29E-02 5.53E-01 positive regulation of cellular response to thapsigargin (GO:1905893) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of cellular response to thapsigargin (GO:1905892) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of cellular response to thapsigargin (GO:1905891) 2 2 .20 + 10.11 4.29E-02 5.52E-01 guanine catabolic process (GO:0006147) 2 2 .20 + 10.11 4.29E-02 5.52E-01 negative regulation of dopamine uptake involved in synaptic transmission (GO:0051585) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of prostaglandin catabolic process (GO:1905828) 1 1 .10 + 10.11 1.72E-01 1.00E00 adenosine 3',5'-bisphosphate transmembrane transport (GO:0071106) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of cellular response to manganese ion (GO:1905802) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of cell migration involved in somitogenic axis elongation (GO:0090249) 1 1 .10 + 10.11 1.72E-01 1.00E00 retinoic acid receptor signaling pathway involved in somitogenesis (GO:0090242) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of glycine import across plasma membrane (GO:1900924) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of cardiac muscle cell contraction (GO:0106135) 1 1 .10 + 10.11 1.72E-01 1.00E00 sorbitol catabolic process (GO:0006062) 1 1 .10 + 10.11 1.72E-01 1.00E00 N-acetylmannosamine metabolic process (GO:0006051) 1 1 .10 + 10.11 1.72E-01 1.00E00 mannosamine metabolic process (GO:0006050) 1 1 .10 + 10.11 1.72E-01 1.00E00 anterograde dendritic transport of mitochondrion (GO:0098972) 1 1 .10 + 10.11 1.72E-01 1.00E00 stress response to zinc ion (GO:1990359) 2 2 .20 + 10.11 4.29E-02 5.51E-01 corticotropin secretion (GO:0051458) 1 1 .10 + 10.11 1.72E-01 1.00E00 hard palate morphogenesis (GO:1905748) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of saliva secretion (GO:1905747) 1 1 .10 + 10.11 1.72E-01 1.00E00 protein-containing complex assembly involved in synapse maturation (GO:0090126) 1 1 .10 + 10.11 1.72E-01 1.00E00 response to linoleic acid (GO:0070543) 1 1 .10 + 10.11 1.72E-01 1.00E00 post-embryonic digestive tract morphogenesis (GO:0048621) 1 1 .10 + 10.11 1.72E-01 1.00E00 glycerol ether catabolic process (GO:0044269) 1 1 .10 + 10.11 1.72E-01 1.00E00 proline import across plasma membrane (GO:1905647) 1 1 .10 + 10.11 1.72E-01 1.00E00 cellular detoxification of cadmium ion (GO:0098849) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of serotonin biosynthetic process (GO:1905627) 1 1 .10 + 10.11 1.72E-01 1.00E00 male meiosis chromosome separation (GO:0051308) 1 1 .10 + 10.11 1.72E-01 1.00E00 neutrophil aggregation (GO:0070488) 2 2 .20 + 10.11 4.29E-02 5.51E-01 positive regulation of cerebral blood circulation (GO:0120277) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of cerebral blood circulation (GO:0120276) 1 1 .10 + 10.11 1.72E-01 1.00E00 stress response to cadmium ion (GO:1990170) 2 2 .20 + 10.11 4.29E-02 5.51E-01 cellular response to interleukin-8 (GO:0098759) 2 2 .20 + 10.11 4.29E-02 5.50E-01 response to interleukin-8 (GO:0098758) 2 2 .20 + 10.11 4.29E-02 5.50E-01 negative regulation of leucine import across plasma membrane (GO:1905533) 2 2 .20 + 10.11 4.29E-02 5.49E-01 regulation of leucine import across plasma membrane (GO:1905532) 2 2 .20 + 10.11 4.29E-02 5.49E-01 symmetric cell division (GO:0098725) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of ERK5 cascade (GO:0070377) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of protein localization to chromatin (GO:0120186) 1 1 .10 + 10.11 1.72E-01 1.00E00 T cell meandering migration (GO:0120117) 1 1 .10 + 10.11 1.72E-01 1.00E00 histone H2A-S139 phosphorylation (GO:0035978) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of synaptic vesicle budding from presynaptic endocytic zone membrane (GO:0098694) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of motor neuron migration (GO:1905485) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of motor neuron migration (GO:1905483) 1 1 .10 + 10.11 1.72E-01 1.00E00 L-xylitol metabolic process (GO:0051164) 1 1 .10 + 10.11 1.72E-01 1.00E00 L-xylitol catabolic process (GO:0051160) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of brain-derived neurotrophic factor receptor signaling pathway (GO:0031550) 1 1 .10 + 10.11 1.72E-01 1.00E00 response to herbicide (GO:0009635) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of quinolinate biosynthetic process (GO:1904985) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of quinolinate biosynthetic process (GO:1904984) 1 1 .10 + 10.11 1.72E-01 1.00E00 glycine import into mitochondrion (GO:1904983) 1 1 .10 + 10.11 1.72E-01 1.00E00 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process (GO:0050653) 1 1 .10 + 10.11 1.72E-01 1.00E00 establishment of endoplasmic reticulum localization to postsynapse (GO:0099089) 1 1 .10 + 10.11 1.72E-01 1.00E00 platelet maturation (GO:0036345) 1 1 .10 + 10.11 1.72E-01 1.00E00 learned vocalization behavior (GO:0098583) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of endosomal vesicle fusion (GO:1905364) 1 1 .10 + 10.11 1.72E-01 1.00E00 dihydrobiopterin metabolic process (GO:0051066) 1 1 .10 + 10.11 1.72E-01 1.00E00 detection of UV (GO:0009589) 1 1 .10 + 10.11 1.72E-01 1.00E00 glycine betaine biosynthetic process (GO:0031456) 1 1 .10 + 10.11 1.72E-01 1.00E00 glycine betaine metabolic process (GO:0031455) 1 1 .10 + 10.11 1.72E-01 1.00E00 transforming growth factor beta receptor signaling pathway involved in heart development (GO:1905313) 1 1 .10 + 10.11 1.72E-01 1.00E00 endothelial to hematopoietic transition (GO:0098508) 1 1 .10 + 10.11 1.72E-01 1.00E00 mitochondrial tyrosyl-tRNA aminoacylation (GO:0070184) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of adiponectin secretion (GO:0070165) 1 1 .10 + 10.11 1.72E-01 1.00E00 Wnt signalosome assembly (GO:1904887) 1 1 .10 + 10.11 1.72E-01 1.00E00 protein trans-autophosphorylation (GO:0036290) 1 1 .10 + 10.11 1.72E-01 1.00E00 response to L-glutamine (GO:1904844) 1 1 .10 + 10.11 1.72E-01 1.00E00 purine nucleobase transmembrane transport (GO:1904823) 1 1 .10 + 10.11 1.72E-01 1.00E00 interleukin-13-mediated signaling pathway (GO:0035772) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of memory T cell differentiation (GO:0043381) 1 1 .10 + 10.11 1.72E-01 1.00E00 T-helper 1 cell cytokine production (GO:0035744) 3 3 .30 + 10.11 1.18E-02 2.44E-01 positive regulation of neutrophil degranulation (GO:0043315) 4 4 .40 + 10.11 3.40E-03 9.44E-02 T-helper 17 cell chemotaxis (GO:0035705) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of eosinophil degranulation (GO:0043310) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of glucagon secretion (GO:0070093) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of protein localization to cell cortex (GO:1904777) 1 1 .10 + 10.11 1.72E-01 1.00E00 mRNA splicing, via endonucleolytic cleavage and ligation (GO:0070054) 1 1 .10 + 10.11 1.72E-01 1.00E00 vascular associated smooth muscle cell migration (GO:1904738) 1 1 .10 + 10.11 1.72E-01 1.00E00 macrophage migration inhibitory factor signaling pathway (GO:0035691) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of erythrocyte enucleation (GO:0061931) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of erythrocyte enucleation (GO:0061930) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of 1-phosphatidylinositol-3-kinase activity (GO:0061903) 2 2 .20 + 10.11 4.29E-02 5.48E-01 regulation of 1-phosphatidylinositol-3-kinase activity (GO:0061901) 2 2 .20 + 10.11 4.29E-02 5.48E-01 daunorubicin transport (GO:0043215) 1 1 .10 + 10.11 1.72E-01 1.00E00 fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow (GO:0035604) 1 1 .10 + 10.11 1.72E-01 1.00E00 fibroblast growth factor receptor signaling pathway involved in hemopoiesis (GO:0035603) 1 1 .10 + 10.11 1.72E-01 1.00E00 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell (GO:0035602) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of cytoplasmic translational elongation (GO:1900248) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of single-species biofilm formation in or on host organism (GO:1900229) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of single-species biofilm formation in or on host organism (GO:1900228) 1 1 .10 + 10.11 1.72E-01 1.00E00 Sertoli cell barrier remodeling (GO:0061843) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of SNARE complex assembly (GO:0035543) 1 1 .10 + 10.11 1.72E-01 1.00E00 otic placode development (GO:1905040) 1 1 .10 + 10.11 1.72E-01 1.00E00 short-chain fatty acid transport (GO:0015912) 1 1 .10 + 10.11 1.72E-01 1.00E00 muscle cell fate specification (GO:0042694) 1 1 .10 + 10.11 1.72E-01 1.00E00 platelet activating factor catabolic process (GO:0062234) 1 1 .10 + 10.11 1.72E-01 1.00E00 L-tryptophan transmembrane transport (GO:1904556) 1 1 .10 + 10.11 1.72E-01 1.00E00 L-proline transmembrane transport (GO:1904555) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of single-species biofilm formation (GO:1900191) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of single-species biofilm formation (GO:1900190) 1 1 .10 + 10.11 1.72E-01 1.00E00 catagen (GO:0042637) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of glycolytic process through fructose-6-phosphate (GO:1904539) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of glycolytic process through fructose-6-phosphate (GO:1904538) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of glial cell-derived neurotrophic factor production (GO:1900168) 2 2 .20 + 10.11 4.29E-02 5.47E-01 regulation of glial cell-derived neurotrophic factor production (GO:1900166) 2 2 .20 + 10.11 4.29E-02 5.47E-01 negative regulation of oligodendrocyte apoptotic process (GO:1900142) 2 2 .20 + 10.11 4.29E-02 5.46E-01 low-density lipoprotein particle mediated signaling (GO:0055096) 2 2 .20 + 10.11 4.29E-02 5.46E-01 lipoprotein particle mediated signaling (GO:0055095) 2 2 .20 + 10.11 4.29E-02 5.45E-01 leukotriene signaling pathway (GO:0061737) 1 1 .10 + 10.11 1.72E-01 1.00E00 angioblast cell migration (GO:0035476) 1 1 .10 + 10.11 1.72E-01 1.00E00 coenzyme A transport (GO:0015880) 1 1 .10 + 10.11 1.72E-01 1.00E00 valine transport (GO:0015829) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of hemoglobin biosynthetic process (GO:0046986) 1 1 .10 + 10.11 1.72E-01 1.00E00 nuclear migration along microfilament (GO:0031022) 2 2 .20 + 10.11 4.29E-02 5.45E-01 radial spoke assembly (GO:0062177) 1 1 .10 + 10.11 1.72E-01 1.00E00 hypoxanthine catabolic process (GO:0009114) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of eIF2 alpha phosphorylation by heme (GO:0010999) 2 2 .20 + 10.11 4.29E-02 5.45E-01 negative regulation of cellular response to heat (GO:1900035) 1 1 .10 + 10.11 1.72E-01 1.00E00 macrophage cytokine production (GO:0010934) 1 1 .10 + 10.11 1.72E-01 1.00E00 pyridoxine biosynthetic process (GO:0008615) 1 1 .10 + 10.11 1.72E-01 1.00E00 pyridoxine metabolic process (GO:0008614) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of non-membrane spanning protein tyrosine kinase activity (GO:1903996) 1 1 .10 + 10.11 1.72E-01 1.00E00 iron ion export across plasma membrane (GO:1903988) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of cellular response to macrophage colony-stimulating factor stimulus (GO:1903974) 2 2 .20 + 10.11 4.29E-02 5.44E-01 positive regulation of response to macrophage colony-stimulating factor (GO:1903971) 2 2 .20 + 10.11 4.29E-02 5.44E-01 helper T cell enhancement of adaptive immune response (GO:0035397) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of chemokine (C-X-C motif) ligand 9 production (GO:0035395) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of chemokine (C-X-C motif) ligand 9 production (GO:0035394) 1 1 .10 + 10.11 1.72E-01 1.00E00 carbon dioxide transmembrane transport (GO:0035378) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of ventricular cardiac muscle cell action potential (GO:1903946) 1 1 .10 + 10.11 1.72E-01 1.00E00 NAD transmembrane transport (GO:0035352) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of actin filament severing (GO:1903920) 1 1 .10 + 10.11 1.72E-01 1.00E00 coenzyme A transmembrane transport (GO:0035349) 1 1 .10 + 10.11 1.72E-01 1.00E00 inosine transport (GO:0035340) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of plasma membrane raft polarization (GO:1903906) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of phosphatidylcholine metabolic process (GO:0150174) 1 1 .10 + 10.11 1.72E-01 1.00E00 response to cycloheximide (GO:0046898) 1 1 .10 + 10.11 1.72E-01 1.00E00 nitrite transport (GO:0015707) 1 1 .10 + 10.11 1.72E-01 1.00E00 terpenoid transport (GO:0046865) 1 1 .10 + 10.11 1.72E-01 1.00E00 isoprenoid transport (GO:0046864) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of protein localization to cell-cell junction (GO:0150107) 1 1 .10 + 10.11 1.72E-01 1.00E00 negative regulation of triglyceride biosynthetic process (GO:0010868) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of maternal process involved in parturition (GO:1904303) 1 1 .10 + 10.11 1.72E-01 1.00E00 regulation of maternal process involved in parturition (GO:1904301) 1 1 .10 + 10.11 1.72E-01 1.00E00 positive regulation of transcytosis (GO:1904300) 2 2 .20 + 10.11 4.29E-02 5.43E-01 glycine secretion, neurotransmission (GO:0061537) 1 1 .10 + 10.11 1.72E-01 9.99E-01 glycine secretion (GO:0061536) 1 1 .10 + 10.11 1.72E-01 9.99E-01 early endosome to recycling endosome transport (GO:0061502) 1 1 .10 + 10.11 1.72E-01 9.98E-01 protein maturation by copper ion transfer (GO:0015680) 1 1 .10 + 10.11 1.72E-01 9.98E-01 glycine import across plasma membrane (GO:1903804) 1 1 .10 + 10.11 1.72E-01 9.98E-01 L-glutamine import across plasma membrane (GO:1903803) 1 1 .10 + 10.11 1.72E-01 9.97E-01 multiple spine synapse organization, single dendrite (GO:0150090) 1 1 .10 + 10.11 1.72E-01 9.97E-01 multiple spine synapse organization (GO:0150089) 1 1 .10 + 10.11 1.72E-01 9.96E-01 positive regulation of protein-glutamine gamma-glutamyltransferase activity (GO:0150074) 1 1 .10 + 10.11 1.72E-01 9.96E-01 regulation of protein-glutamine gamma-glutamyltransferase activity (GO:0150073) 1 1 .10 + 10.11 1.72E-01 9.96E-01 positive regulation of arginase activity (GO:0150072) 1 1 .10 + 10.11 1.72E-01 9.95E-01 regulation of arginase activity (GO:0150070) 1 1 .10 + 10.11 1.72E-01 9.95E-01 vertebrate eye-specific patterning (GO:0150064) 3 3 .30 + 10.11 1.18E-02 2.44E-01 oxidised low-density lipoprotein particle clearance (GO:0150024) 1 1 .10 + 10.11 1.72E-01 9.95E-01 regulation of transcytosis (GO:1904298) 2 2 .20 + 10.11 4.29E-02 5.43E-01 L-proline import across plasma membrane (GO:1904271) 1 1 .10 + 10.11 1.72E-01 9.94E-01 lateral motor column neuron migration (GO:0097477) 1 1 .10 + 10.11 1.72E-01 9.94E-01 positive regulation of iron ion transmembrane transporter activity (GO:1904256) 1 1 .10 + 10.11 1.72E-01 9.93E-01 regulation of iron ion transmembrane transporter activity (GO:1904254) 1 1 .10 + 10.11 1.72E-01 9.93E-01 negative regulation of polynucleotide adenylyltransferase activity (GO:1904246) 1 1 .10 + 10.11 1.72E-01 9.93E-01 endocardial cushion cell fate commitment (GO:0061445) 1 1 .10 + 10.11 1.72E-01 9.92E-01 renal artery morphogenesis (GO:0061441) 1 1 .10 + 10.11 1.72E-01 9.92E-01 negative regulation of cell proliferation in bone marrow (GO:1903769) 1 1 .10 + 10.11 1.72E-01 9.92E-01 negative regulation of I-kappaB phosphorylation (GO:1903720) 1 1 .10 + 10.11 1.72E-01 9.91E-01 asparagine transmembrane transport (GO:1903713) 1 1 .10 + 10.11 1.72E-01 9.91E-01 cell migration involved in coronary vasculogenesis (GO:0060980) 1 1 .10 + 10.11 1.72E-01 9.90E-01 response to chromate (GO:0046687) 1 1 .10 + 10.11 1.72E-01 9.90E-01 endocardial cell fate commitment (GO:0060957) 1 1 .10 + 10.11 1.72E-01 9.90E-01 negative regulation of retinal cell programmed cell death (GO:0046671) 1 1 .10 + 10.11 1.72E-01 9.89E-01 cardiac neuron differentiation (GO:0060945) 1 1 .10 + 10.11 1.72E-01 9.89E-01 negative regulation of microglial cell mediated cytotoxicity (GO:1904150) 1 1 .10 + 10.11 1.72E-01 9.89E-01 melanocyte proliferation (GO:0097325) 1 1 .10 + 10.11 1.72E-01 9.88E-01 basophil differentiation (GO:0030221) 1 1 .10 + 10.11 1.72E-01 9.88E-01 heparan sulfate proteoglycan catabolic process (GO:0030200) 3 3 .30 + 10.11 1.18E-02 2.43E-01 positive regulation of Schwann cell proliferation (GO:0010625) 1 1 .10 + 10.11 1.72E-01 9.87E-01 positive regulation of complement-dependent cytotoxicity (GO:1903661) 1 1 .10 + 10.11 1.72E-01 9.87E-01 venous endothelial cell differentiation (GO:0060843) 1 1 .10 + 10.11 1.72E-01 9.87E-01 halogenated hydrocarbon metabolic process (GO:0042197) 1 1 .10 + 10.11 1.72E-01 9.86E-01 positive regulation of trophectodermal cell proliferation (GO:1904075) 1 1 .10 + 10.11 1.72E-01 9.86E-01 regulation of trophectodermal cell proliferation (GO:1904073) 1 1 .10 + 10.11 1.72E-01 9.86E-01 complement-dependent cytotoxicity (GO:0097278) 2 2 .20 + 10.11 4.29E-02 5.42E-01 negative regulation of locomotor rhythm (GO:1904060) 1 1 .10 + 10.11 1.72E-01 9.85E-01 negative regulation of sensory perception of pain (GO:1904057) 1 1 .10 + 10.11 1.72E-01 9.85E-01 uroporphyrinogen III metabolic process (GO:0046502) 2 2 .20 + 10.11 4.29E-02 5.42E-01 late meiotic recombination nodule assembly (GO:0042140) 1 1 .10 + 10.11 1.72E-01 9.84E-01 glutamine secretion (GO:0010585) 1 1 .10 + 10.11 1.72E-01 9.84E-01 protein galactosylation (GO:0042125) 1 1 .10 + 10.11 1.72E-01 9.84E-01 negative regulation of lymphocyte anergy (GO:0002912) 1 1 .10 + 10.11 1.72E-01 9.83E-01 cellular response to anisomycin (GO:0072740) 1 1 .10 + 10.11 1.72E-01 9.83E-01 negative regulation of mast cell chemotaxis (GO:0060755) 1 1 .10 + 10.11 1.72E-01 9.83E-01 lactosylceramide metabolic process (GO:0046478) 1 1 .10 + 10.11 1.72E-01 9.82E-01 cellular response to sorbitol (GO:0072709) 1 1 .10 + 10.11 1.72E-01 9.82E-01 cellular response to methyl methanesulfonate (GO:0072703) 1 1 .10 + 10.11 1.72E-01 9.81E-01 response to methyl methanesulfonate (GO:0072702) 1 1 .10 + 10.11 1.72E-01 9.81E-01 plasma lipoprotein particle oxidation (GO:0034441) 1 1 .10 + 10.11 1.72E-01 9.81E-01 regulation of skeletal muscle contraction via regulation of action potential (GO:0014861) 1 1 .10 + 10.11 1.72E-01 9.80E-01 negative regulation of chronic inflammatory response to non-antigenic stimulus (GO:0002881) 1 1 .10 + 10.11 1.72E-01 9.80E-01 negative regulation of chronic inflammatory response to antigenic stimulus (GO:0002875) 1 1 .10 + 10.11 1.72E-01 9.80E-01 negative regulation of chondrocyte development (GO:0061182) 1 1 .10 + 10.11 1.72E-01 9.79E-01 biosynthetic process of antibacterial peptides active against Gram-negative bacteria (GO:0002812) 1 1 .10 + 10.11 1.72E-01 9.79E-01 Peyer's patch morphogenesis (GO:0061146) 1 1 .10 + 10.11 1.72E-01 9.79E-01 positive regulation of cytolysis (GO:0045919) 1 1 .10 + 10.11 1.72E-01 9.78E-01 negative regulation of cytolysis (GO:0045918) 1 1 .10 + 10.11 1.72E-01 9.78E-01 dense core granule biogenesis (GO:0061110) 1 1 .10 + 10.11 1.72E-01 9.77E-01 seminal vesicle epithelium development (GO:0061108) 1 1 .10 + 10.11 1.72E-01 9.77E-01 negative regulation of stomach neuroendocrine cell differentiation (GO:0061106) 1 1 .10 + 10.11 1.72E-01 9.77E-01 regulation of stomach neuroendocrine cell differentiation (GO:0061105) 1 1 .10 + 10.11 1.72E-01 9.76E-01 positive regulation of constitutive secretory pathway (GO:1903435) 1 1 .10 + 10.11 1.72E-01 9.76E-01 neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration (GO:0021944) 1 1 .10 + 10.11 1.72E-01 9.76E-01 radial glia guided migration of cerebellar granule cell (GO:0021933) 1 1 .10 + 10.11 1.72E-01 9.75E-01 negative regulation of P-type sodium:potassium-exchanging transporter activity (GO:1903407) 1 1 .10 + 10.11 1.72E-01 9.75E-01 Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation (GO:0003270) 1 1 .10 + 10.11 1.72E-01 9.75E-01 regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling (GO:0060668) 1 1 .10 + 10.11 1.72E-01 9.74E-01 negative regulation of neurofibrillary tangle assembly (GO:1902997) 1 1 .10 + 10.11 1.72E-01 9.74E-01 regulation of transcription from RNA polymerase II promoter in response to iron (GO:0034395) 2 2 .20 + 10.11 4.29E-02 5.41E-01 positive regulation of early endosome to recycling endosome transport (GO:1902955) 1 1 .10 + 10.11 1.72E-01 9.73E-01 regulation of intracellular calcium activated chloride channel activity (GO:1902938) 1 1 .10 + 10.11 1.72E-01 9.73E-01 NAD salvage (GO:0034355) 1 1 .10 + 10.11 1.72E-01 9.73E-01 antibacterial peptide biosynthetic process (GO:0002780) 1 1 .10 + 10.11 1.72E-01 9.72E-01 antibacterial peptide production (GO:0002778) 1 1 .10 + 10.11 1.72E-01 9.72E-01 antimicrobial peptide biosynthetic process (GO:0002777) 1 1 .10 + 10.11 1.72E-01 9.72E-01 antimicrobial peptide production (GO:0002775) 1 1 .10 + 10.11 1.72E-01 9.71E-01 positive regulation of muscle hyperplasia (GO:0014739) 1 1 .10 + 10.11 1.72E-01 9.71E-01 negative regulation of natural killer cell cytokine production (GO:0002728) 1 1 .10 + 10.11 1.72E-01 9.71E-01 myeloid leukocyte cytokine production (GO:0061082) 1 1 .10 + 10.11 1.72E-01 9.70E-01 maintenance of symbiont-containing vacuole by host (GO:0085018) 1 1 .10 + 10.11 1.72E-01 9.70E-01 detoxification of zinc ion (GO:0010312) 2 2 .20 + 10.11 4.29E-02 5.41E-01 blood coagulation, intrinsic pathway (GO:0007597) 1 1 .10 + 10.11 1.72E-01 9.69E-01 pentitol catabolic process (GO:0019527) 1 1 .10 + 10.11 1.72E-01 9.69E-01 pentitol metabolic process (GO:0019519) 1 1 .10 + 10.11 1.72E-01 9.69E-01 coronary sinus valve morphogenesis (GO:0003182) 1 1 .10 + 10.11 1.72E-01 9.68E-01 coronary sinus valve development (GO:0003178) 1 1 .10 + 10.11 1.72E-01 9.68E-01 neural crest cell migration involved in heart formation (GO:0003147) 1 1 .10 + 10.11 1.72E-01 9.68E-01 AMP transport (GO:0080121) 1 1 .10 + 10.11 1.72E-01 9.67E-01 squamous basal epithelial stem cell differentiation involved in prostate gland acinus development (GO:0060529) 1 1 .10 + 10.11 1.72E-01 9.67E-01 regulation of neuronal signal transduction (GO:1902847) 1 1 .10 + 10.11 1.72E-01 9.67E-01 regulation of nuclear migration along microtubule (GO:1902838) 1 1 .10 + 10.11 1.72E-01 9.66E-01 positive regulation of neutrophil activation (GO:1902565) 6 5 .59 + 8.43 1.70E-03 5.52E-02 positive regulation of type IIa hypersensitivity (GO:0001798) 6 5 .59 + 8.43 1.70E-03 5.51E-02 regulation of type IIa hypersensitivity (GO:0001796) 6 5 .59 + 8.43 1.70E-03 5.50E-02 Fc-gamma receptor signaling pathway (GO:0038094) 6 5 .59 + 8.43 1.70E-03 5.49E-02 positive regulation of type II hypersensitivity (GO:0002894) 6 5 .59 + 8.43 1.70E-03 5.48E-02 regulation of type II hypersensitivity (GO:0002892) 6 5 .59 + 8.43 1.70E-03 5.46E-02 neutrophil extravasation (GO:0072672) 6 5 .59 + 8.43 1.70E-03 5.45E-02 microglia development (GO:0014005) 5 4 .49 + 8.09 5.68E-03 1.40E-01 regulation of microglial cell mediated cytotoxicity (GO:1904149) 5 4 .49 + 8.09 5.68E-03 1.40E-01 protoporphyrinogen IX metabolic process (GO:0046501) 5 4 .49 + 8.09 5.68E-03 1.40E-01 regulation of neutrophil degranulation (GO:0043313) 9 7 .89 + 7.87 2.60E-04 1.19E-02 imidazole-containing compound metabolic process (GO:0052803) 4 3 .40 + 7.59 1.93E-02 3.40E-01 blood coagulation, fibrin clot formation (GO:0072378) 4 3 .40 + 7.59 1.93E-02 3.40E-01 negative regulation of dendritic cell differentiation (GO:2001199) 4 3 .40 + 7.59 1.93E-02 3.39E-01 positive regulation of type III hypersensitivity (GO:0001805) 4 3 .40 + 7.59 1.93E-02 3.39E-01 regulation of type III hypersensitivity (GO:0001803) 4 3 .40 + 7.59 1.93E-02 3.38E-01 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell (GO:0002291) 4 3 .40 + 7.59 1.93E-02 3.38E-01 histamine metabolic process (GO:0001692) 4 3 .40 + 7.59 1.93E-02 3.38E-01 negative regulation of neutrophil apoptotic process (GO:0033030) 4 3 .40 + 7.59 1.93E-02 3.37E-01 complement-mediated synapse pruning (GO:0150062) 4 3 .40 + 7.59 1.93E-02 3.37E-01 positive regulation of microglial cell mediated cytotoxicity (GO:1904151) 4 3 .40 + 7.59 1.93E-02 3.36E-01 neutrophil clearance (GO:0097350) 4 3 .40 + 7.59 1.93E-02 3.36E-01 proteoglycan catabolic process (GO:0030167) 4 3 .40 + 7.59 1.93E-02 3.36E-01 negative regulation of extracellular matrix constituent secretion (GO:0003332) 4 3 .40 + 7.59 1.93E-02 3.35E-01 regulation of hemoglobin biosynthetic process (GO:0046984) 7 5 .69 + 7.22 2.71E-03 7.88E-02 stress response to metal ion (GO:0097501) 7 5 .69 + 7.22 2.71E-03 7.86E-02 negative regulation of pro-B cell differentiation (GO:2000974) 3 2 .30 + 6.74 6.73E-02 7.44E-01 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II (GO:0002581) 3 2 .30 + 6.74 6.73E-02 7.43E-01 pro-T cell differentiation (GO:0002572) 3 2 .30 + 6.74 6.73E-02 7.43E-01 purine nucleobase transport (GO:0006863) 3 2 .30 + 6.74 6.73E-02 7.42E-01 immune complex clearance (GO:0002434) 3 2 .30 + 6.74 6.73E-02 7.42E-01 regulation of type I hypersensitivity (GO:0001810) 6 4 .59 + 6.74 8.80E-03 1.96E-01 negative regulation of macrophage inflammatory protein 1 alpha production (GO:0071641) 3 2 .30 + 6.74 6.73E-02 7.41E-01 defense response to nematode (GO:0002215) 3 2 .30 + 6.74 6.73E-02 7.41E-01 negative regulation of MHC class II biosynthetic process (GO:0045347) 6 4 .59 + 6.74 8.80E-03 1.96E-01 circadian temperature homeostasis (GO:0060086) 3 2 .30 + 6.74 6.73E-02 7.40E-01 interleukin-3-mediated signaling pathway (GO:0038156) 3 2 .30 + 6.74 6.73E-02 7.40E-01 positive regulation of blood vessel remodeling (GO:2000504) 3 2 .30 + 6.74 6.73E-02 7.39E-01 negative regulation of epinephrine secretion (GO:0032811) 3 2 .30 + 6.74 6.73E-02 7.39E-01 regulation of zinc ion transport (GO:0071579) 3 2 .30 + 6.74 6.73E-02 7.38E-01 regulation of peroxidase activity (GO:2000468) 3 2 .30 + 6.74 6.73E-02 7.38E-01 regulation of macrophage migration inhibitory factor signaling pathway (GO:2000446) 3 2 .30 + 6.74 6.73E-02 7.37E-01 positive regulation of eosinophil migration (GO:2000418) 3 2 .30 + 6.74 6.73E-02 7.36E-01 regulation of epinephrine secretion (GO:0014060) 3 2 .30 + 6.74 6.73E-02 7.36E-01 microglia differentiation (GO:0014004) 6 4 .59 + 6.74 8.80E-03 1.96E-01 neutrophil-mediated killing of gram-positive bacterium (GO:0070946) 3 2 .30 + 6.74 6.73E-02 7.35E-01 response to vitamin K (GO:0032571) 3 2 .30 + 6.74 6.73E-02 7.35E-01 cellular response to mercury ion (GO:0071288) 3 2 .30 + 6.74 6.73E-02 7.34E-01 membrane disruption in other organism (GO:0051673) 3 2 .30 + 6.74 6.73E-02 7.34E-01 host-mediated regulation of intestinal microbiota composition (GO:0048874) 3 2 .30 + 6.74 6.73E-02 7.33E-01 deoxyguanosine catabolic process (GO:0006161) 3 2 .30 + 6.74 6.73E-02 7.33E-01 purine nucleobase catabolic process (GO:0006145) 3 2 .30 + 6.74 6.73E-02 7.32E-01 synapse pruning (GO:0098883) 9 6 .89 + 6.74 1.29E-03 4.43E-02 leucine import across plasma membrane (GO:0098713) 3 2 .30 + 6.74 6.73E-02 7.32E-01 sequestering of calcium ion (GO:0051208) 3 2 .30 + 6.74 6.73E-02 7.31E-01 cellular response to interleukin-13 (GO:0035963) 3 2 .30 + 6.74 6.73E-02 7.31E-01 response to interleukin-13 (GO:0035962) 3 2 .30 + 6.74 6.73E-02 7.30E-01 negative regulation of lymphoid progenitor cell differentiation (GO:1905457) 3 2 .30 + 6.74 6.73E-02 7.30E-01 positive regulation of NK T cell proliferation (GO:0051142) 3 2 .30 + 6.74 6.73E-02 7.29E-01 ceramide translocation (GO:0099040) 3 2 .30 + 6.74 6.73E-02 7.29E-01 negative regulation of aspartic-type peptidase activity (GO:1905246) 3 2 .30 + 6.74 6.73E-02 7.28E-01 T-helper 1 cell activation (GO:0035711) 3 2 .30 + 6.74 6.73E-02 7.28E-01 negative regulation of neutrophil degranulation (GO:0043314) 3 2 .30 + 6.74 6.73E-02 7.27E-01 neutrophil degranulation (GO:0043312) 3 2 .30 + 6.74 6.73E-02 7.27E-01 ubiquitin-dependent endocytosis (GO:0070086) 3 2 .30 + 6.74 6.73E-02 7.26E-01 regulation of oligodendrocyte apoptotic process (GO:1900141) 3 2 .30 + 6.74 6.73E-02 7.26E-01 glycerol transport (GO:0015793) 3 2 .30 + 6.74 6.73E-02 7.25E-01 deoxyguanosine metabolic process (GO:0042453) 3 2 .30 + 6.74 6.73E-02 7.24E-01 L-leucine import across plasma membrane (GO:1903801) 3 2 .30 + 6.74 6.73E-02 7.24E-01 basement membrane disassembly (GO:0034769) 3 2 .30 + 6.74 6.73E-02 7.23E-01 positive regulation of substrate-dependent cell migration, cell attachment to substrate (GO:1904237) 3 2 .30 + 6.74 6.73E-02 7.23E-01 regulation of substrate-dependent cell migration, cell attachment to substrate (GO:1904235) 3 2 .30 + 6.74 6.73E-02 7.22E-01 regulation of cytolysis (GO:0042268) 3 2 .30 + 6.74 6.73E-02 7.22E-01 intestinal cholesterol absorption (GO:0030299) 3 2 .30 + 6.74 6.73E-02 7.21E-01 regulation of P-type sodium:potassium-exchanging transporter activity (GO:1903406) 3 2 .30 + 6.74 6.73E-02 7.21E-01 dichotomous subdivision of terminal units involved in salivary gland branching (GO:0060666) 3 2 .30 + 6.74 6.73E-02 7.20E-01 regulation of neurofibrillary tangle assembly (GO:1902996) 3 2 .30 + 6.74 6.73E-02 7.20E-01 negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process (GO:1902960) 3 2 .30 + 6.74 6.73E-02 7.19E-01 negative regulation of tau-protein kinase activity (GO:1902948) 3 2 .30 + 6.74 6.73E-02 7.19E-01 cell surface pattern recognition receptor signaling pathway (GO:0002752) 3 2 .30 + 6.74 6.73E-02 7.18E-01 endodermal digestive tract morphogenesis (GO:0061031) 3 2 .30 + 6.74 6.73E-02 7.18E-01 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration (GO:0021817) 3 2 .30 + 6.74 6.73E-02 7.17E-01 regulation of dendritic cell antigen processing and presentation (GO:0002604) 8 5 .79 + 6.32 4.07E-03 1.08E-01 activated T cell proliferation (GO:0050798) 8 5 .79 + 6.32 4.07E-03 1.08E-01 response to stilbenoid (GO:0035634) 8 5 .79 + 6.32 4.07E-03 1.07E-01 glycine transport (GO:0015816) 8 5 .79 + 6.32 4.07E-03 1.07E-01 regulation of neutrophil activation (GO:1902563) 13 8 1.29 + 6.22 2.94E-04 1.32E-02 regulation of sodium ion export across plasma membrane (GO:1903276) 5 3 .49 + 6.07 2.88E-02 4.46E-01 toll-like receptor 7 signaling pathway (GO:0034154) 5 3 .49 + 6.07 2.88E-02 4.45E-01 hypersensitivity (GO:0002524) 5 3 .49 + 6.07 2.88E-02 4.45E-01 positive regulation of type I hypersensitivity (GO:0001812) 5 3 .49 + 6.07 2.88E-02 4.45E-01 Fc receptor signaling pathway (GO:0038093) 10 6 .99 + 6.07 1.90E-03 5.96E-02 negative regulation of glutamate secretion (GO:0014050) 5 3 .49 + 6.07 2.88E-02 4.44E-01 neutrophil-mediated killing of gram-negative bacterium (GO:0070945) 5 3 .49 + 6.07 2.88E-02 4.44E-01 heat generation (GO:0031649) 5 3 .49 + 6.07 2.88E-02 4.43E-01 thyroid hormone transport (GO:0070327) 5 3 .49 + 6.07 2.88E-02 4.43E-01 interleukin-27-mediated signaling pathway (GO:0070106) 5 3 .49 + 6.07 2.88E-02 4.42E-01 monocyte extravasation (GO:0035696) 5 3 .49 + 6.07 2.88E-02 4.42E-01 interleukin-18-mediated signaling pathway (GO:0035655) 5 3 .49 + 6.07 2.88E-02 4.41E-01 carnitine transport (GO:0015879) 5 3 .49 + 6.07 2.88E-02 4.41E-01 positive regulation of hemoglobin biosynthetic process (GO:0046985) 5 3 .49 + 6.07 2.88E-02 4.41E-01 canalicular bile acid transport (GO:0015722) 5 3 .49 + 6.07 2.88E-02 4.40E-01 regulation of tau-protein kinase activity (GO:1902947) 12 7 1.19 + 5.90 8.98E-04 3.33E-02 positive regulation of monocyte chemotaxis (GO:0090026) 19 11 1.88 + 5.86 3.29E-05 2.06E-03 negative regulation of antigen processing and presentation (GO:0002578) 7 4 .69 + 5.78 1.29E-02 2.58E-01 regulation of dendritic cell differentiation (GO:2001198) 7 4 .69 + 5.78 1.29E-02 2.58E-01 positive regulation of T-helper 1 cell cytokine production (GO:2000556) 7 4 .69 + 5.78 1.29E-02 2.57E-01 regulation of T-helper 1 cell cytokine production (GO:2000554) 7 4 .69 + 5.78 1.29E-02 2.57E-01 cellular response to vitamin (GO:0071295) 7 4 .69 + 5.78 1.29E-02 2.57E-01 antifungal innate immune response (GO:0061760) 7 4 .69 + 5.78 1.29E-02 2.56E-01 autocrine signaling (GO:0035425) 7 4 .69 + 5.78 1.29E-02 2.56E-01 amino-acid betaine transport (GO:0015838) 7 4 .69 + 5.78 1.29E-02 2.56E-01 detoxification of inorganic compound (GO:0061687) 7 4 .69 + 5.78 1.29E-02 2.55E-01 negative regulation of extracellular matrix organization (GO:1903054) 9 5 .89 + 5.62 5.87E-03 1.43E-01 porphyrin-containing compound biosynthetic process (GO:0006779) 27 15 2.67 + 5.62 1.82E-06 1.68E-04 neutrophil-mediated killing of bacterium (GO:0070944) 9 5 .89 + 5.62 5.87E-03 1.42E-01 neutrophil-mediated killing of symbiont cell (GO:0070943) 9 5 .89 + 5.62 5.87E-03 1.42E-01 neutrophil mediated cytotoxicity (GO:0070942) 9 5 .89 + 5.62 5.87E-03 1.42E-01 tetrapyrrole biosynthetic process (GO:0033014) 27 15 2.67 + 5.62 1.82E-06 1.67E-04 positive regulation of hypersensitivity (GO:0002885) 9 5 .89 + 5.62 5.87E-03 1.42E-01 response to yeast (GO:0001878) 11 6 1.09 + 5.52 2.72E-03 7.90E-02 cell junction disassembly (GO:0150146) 11 6 1.09 + 5.52 2.72E-03 7.88E-02 killing by host of symbiont cells (GO:0051873) 13 7 1.29 + 5.45 1.28E-03 4.44E-02 positive regulation of astrocyte differentiation (GO:0048711) 13 7 1.29 + 5.45 1.28E-03 4.43E-02 negative regulation of neuroinflammatory response (GO:0150079) 13 7 1.29 + 5.45 1.28E-03 4.42E-02 regulation of hypersensitivity (GO:0002883) 13 7 1.29 + 5.45 1.28E-03 4.41E-02 porphyrin-containing compound metabolic process (GO:0006778) 36 19 3.56 + 5.34 1.43E-07 1.84E-05 phagocytosis, recognition (GO:0006910) 74 38 7.32 + 5.19 1.77E-13 5.16E-11 detoxification of copper ion (GO:0010273) 4 2 .40 + 5.06 9.51E-02 8.76E-01 response to oleic acid (GO:0034201) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of tolerance induction (GO:0002644) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of potassium ion import across plasma membrane (GO:1903288) 6 3 .59 + 5.06 4.04E-02 5.44E-01 positive regulation of calcium:sodium antiporter activity (GO:1903281) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of calcium:sodium antiporter activity (GO:1903279) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of sodium ion export across plasma membrane (GO:1903278) 4 2 .40 + 5.06 9.51E-02 8.75E-01 glial cell fate specification (GO:0021780) 2 1 .20 + 5.06 2.46E-01 1.00E00 oligodendrocyte cell fate commitment (GO:0021779) 2 1 .20 + 5.06 2.46E-01 1.00E00 oligodendrocyte cell fate specification (GO:0021778) 2 1 .20 + 5.06 2.46E-01 1.00E00 smoothened signaling pathway involved in spinal cord motor neuron cell fate specification (GO:0021776) 2 1 .20 + 5.06 2.46E-01 1.00E00 smoothened signaling pathway involved in ventral spinal cord interneuron specification (GO:0021775) 2 1 .20 + 5.06 2.46E-01 1.00E00 orbitofrontal cortex development (GO:0021769) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of the force of heart contraction by chemical signal (GO:0003099) 2 1 .20 + 5.06 2.46E-01 1.00E00 renal water transport (GO:0003097) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of inner ear receptor cell differentiation (GO:2000981) 4 2 .40 + 5.06 9.51E-02 8.75E-01 activation of meiosis involved in egg activation (GO:0060466) 2 1 .20 + 5.06 2.46E-01 1.00E00 glycerol-3-phosphate catabolic process (GO:0046168) 2 1 .20 + 5.06 2.46E-01 1.00E00 triglyceride transport (GO:0034197) 2 1 .20 + 5.06 2.46E-01 1.00E00 acylglycerol transport (GO:0034196) 2 1 .20 + 5.06 2.46E-01 1.00E00 4-nitrophenol metabolic process (GO:0018960) 2 1 .20 + 5.06 2.46E-01 1.00E00 pigment catabolic process (GO:0046149) 4 2 .40 + 5.06 9.51E-02 8.74E-01 negative regulation of growth hormone receptor signaling pathway (GO:0060400) 2 1 .20 + 5.06 2.46E-01 1.00E00 purine deoxyribonucleoside catabolic process (GO:0046124) 4 2 .40 + 5.06 9.51E-02 8.74E-01 toll-like receptor 8 signaling pathway (GO:0034158) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of antigen processing and presentation of peptide antigen via MHC class II (GO:0002587) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of MyD88-dependent toll-like receptor signaling pathway (GO:0034125) 2 1 .20 + 5.06 2.46E-01 1.00E00 establishment or maintenance of cell polarity regulating cell shape (GO:0071963) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of erythrocyte aggregation (GO:0034118) 2 1 .20 + 5.06 2.46E-01 1.00E00 leukotriene production involved in inflammatory response (GO:0002540) 2 1 .20 + 5.06 2.46E-01 1.00E00 nitric oxide production involved in inflammatory response (GO:0002537) 2 1 .20 + 5.06 2.46E-01 1.00E00 cytokine production involved in inflammatory response (GO:0002534) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of vascular permeability involved in acute inflammatory response (GO:0002528) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of neutrophil differentiation (GO:0045659) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of mechanoreceptor differentiation (GO:0045632) 4 2 .40 + 5.06 9.51E-02 8.73E-01 cyclooxygenase pathway (GO:0019371) 4 2 .40 + 5.06 9.51E-02 8.73E-01 third ventricle development (GO:0021678) 4 2 .40 + 5.06 9.51E-02 8.72E-01 negative regulation of inner ear auditory receptor cell differentiation (GO:0045608) 4 2 .40 + 5.06 9.51E-02 8.72E-01 vestibulocochlear nerve formation (GO:0021650) 2 1 .20 + 5.06 2.46E-01 1.00E00 vestibulocochlear nerve structural organization (GO:0021649) 2 1 .20 + 5.06 2.46E-01 1.00E00 vestibulocochlear nerve morphogenesis (GO:0021648) 4 2 .40 + 5.06 9.51E-02 8.71E-01 minus-end-directed vesicle transport along microtubule (GO:0072382) 2 1 .20 + 5.06 2.46E-01 1.00E00 protein activation cascade (GO:0072376) 6 3 .59 + 5.06 4.04E-02 5.44E-01 regulation of progesterone secretion (GO:2000870) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of estradiol secretion (GO:2000864) 2 1 .20 + 5.06 2.46E-01 1.00E00 guanine metabolic process (GO:0046098) 4 2 .40 + 5.06 9.51E-02 8.71E-01 deoxyinosine metabolic process (GO:0046094) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of corticosterone secretion (GO:2000852) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of glucocorticoid secretion (GO:2000851) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of testosterone secretion (GO:2000845) 2 1 .20 + 5.06 2.46E-01 1.00E00 arsonoacetate metabolic process (GO:0018872) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of blood vessel remodeling (GO:0060313) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of blood vessel remodeling (GO:0060312) 8 4 .79 + 5.06 1.79E-02 3.25E-01 ADP catabolic process (GO:0046032) 4 2 .40 + 5.06 9.51E-02 8.70E-01 negative regulation of cytokine activity (GO:0060302) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of cytokine activity (GO:0060300) 2 1 .20 + 5.06 2.46E-01 1.00E00 cellular cadmium ion homeostasis (GO:0006876) 2 1 .20 + 5.06 2.46E-01 1.00E00 antigen processing and presentation of peptide antigen via MHC class II (GO:0002495) 18 9 1.78 + 5.06 3.96E-04 1.67E-02 negative regulation of apoptotic process in bone marrow cell (GO:0071866) 4 2 .40 + 5.06 9.51E-02 8.70E-01 regulation of apoptotic process in bone marrow cell (GO:0071865) 4 2 .40 + 5.06 9.51E-02 8.69E-01 dendritic cell antigen processing and presentation (GO:0002468) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of nitrogen utilization (GO:0006808) 2 1 .20 + 5.06 2.46E-01 1.00E00 acute inflammatory response to antigenic stimulus (GO:0002438) 12 6 1.19 + 5.06 3.78E-03 1.02E-01 response to nickel cation (GO:0010045) 2 1 .20 + 5.06 2.46E-01 1.00E00 response to aluminum ion (GO:0010044) 2 1 .20 + 5.06 2.46E-01 1.00E00 granuloma formation (GO:0002432) 2 1 .20 + 5.06 2.46E-01 1.00E00 Fc receptor mediated stimulatory signaling pathway (GO:0002431) 6 3 .59 + 5.06 4.04E-02 5.44E-01 complement receptor mediated signaling pathway (GO:0002430) 8 4 .79 + 5.06 1.79E-02 3.25E-01 negative regulation of B cell differentiation (GO:0045578) 4 2 .40 + 5.06 9.51E-02 8.69E-01 response to carbon dioxide (GO:0010037) 2 1 .20 + 5.06 2.46E-01 1.00E00 immune response to tumor cell (GO:0002418) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of semaphorin-plexin signaling pathway (GO:2001260) 2 1 .20 + 5.06 2.46E-01 1.00E00 fourth ventricle development (GO:0021592) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of vasculogenesis (GO:2001213) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of the force of heart contraction by epinephrine-norepinephrine (GO:0001997) 2 1 .20 + 5.06 2.46E-01 1.00E00 trochlear nerve development (GO:0021558) 2 1 .20 + 5.06 2.46E-01 1.00E00 spinal cord oligodendrocyte cell differentiation (GO:0021529) 2 1 .20 + 5.06 2.46E-01 1.00E00 somatic motor neuron differentiation (GO:0021523) 2 1 .20 + 5.06 2.46E-01 1.00E00 ventral spinal cord interneuron specification (GO:0021521) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of exocyst assembly (GO:0001928) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of ovulation (GO:0060279) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of ovulation (GO:0060278) 2 1 .20 + 5.06 2.46E-01 1.00E00 metanephric loop of Henle development (GO:0072236) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of respiratory burst involved in inflammatory response (GO:0060265) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of hippocampal neuron apoptotic process (GO:0110089) 6 3 .59 + 5.06 4.04E-02 5.43E-01 negative regulation of eosinophil activation (GO:1902567) 2 1 .20 + 5.06 2.46E-01 1.00E00 heme oxidation (GO:0006788) 2 1 .20 + 5.06 2.46E-01 1.00E00 porphyrin-containing compound catabolic process (GO:0006787) 4 2 .40 + 5.06 9.51E-02 8.68E-01 protoporphyrinogen IX biosynthetic process (GO:0006782) 2 1 .20 + 5.06 2.46E-01 1.00E00 glucocorticoid catabolic process (GO:0006713) 2 1 .20 + 5.06 2.46E-01 1.00E00 cellular response to diacyl bacterial lipopeptide (GO:0071726) 4 2 .40 + 5.06 9.51E-02 8.68E-01 response to diacyl bacterial lipopeptide (GO:0071724) 4 2 .40 + 5.06 9.51E-02 8.67E-01 negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell (GO:2001189) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of ATP biosynthetic process (GO:2001170) 4 2 .40 + 5.06 9.51E-02 8.66E-01 B cell proliferation involved in immune response (GO:0002322) 6 3 .59 + 5.06 4.04E-02 5.43E-01 plasma cell differentiation (GO:0002317) 4 2 .40 + 5.06 9.51E-02 8.66E-01 germinal center B cell differentiation (GO:0002314) 6 3 .59 + 5.06 4.04E-02 5.42E-01 nitric oxide homeostasis (GO:0033484) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of Rho guanyl-nucleotide exchange factor activity (GO:2001107) 2 1 .20 + 5.06 2.46E-01 1.00E00 complement activation, lectin pathway (GO:0001867) 4 2 .40 + 5.06 9.51E-02 8.65E-01 calcium-independent cell-matrix adhesion (GO:0007161) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of epithelial cell differentiation involved in kidney development (GO:2000697) 2 1 .20 + 5.06 2.46E-01 1.00E00 distal tubule morphogenesis (GO:0072156) 2 1 .20 + 5.06 2.46E-01 1.00E00 inner cell mass cellular morphogenesis (GO:0001828) 2 1 .20 + 5.06 2.46E-01 1.00E00 inner cell mass cell fate commitment (GO:0001827) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of interleukin-1-mediated signaling pathway (GO:2000660) 4 2 .40 + 5.06 9.51E-02 8.65E-01 positive regulation of protein autoubiquitination (GO:1902499) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of adenosine receptor signaling pathway (GO:0060167) 2 1 .20 + 5.06 2.46E-01 1.00E00 inositol trisphosphate biosynthetic process (GO:0032959) 4 2 .40 + 5.06 9.51E-02 8.64E-01 negative regulation of phagocytosis, engulfment (GO:0060101) 2 1 .20 + 5.06 2.46E-01 1.00E00 CDP-choline pathway (GO:0006657) 2 1 .20 + 5.06 2.46E-01 1.00E00 microglial cell activation involved in immune response (GO:0002282) 4 2 .40 + 5.06 9.51E-02 8.64E-01 plasmacytoid dendritic cell differentiation (GO:0002273) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of IP-10 production (GO:0071658) 2 1 .20 + 5.06 2.46E-01 1.00E00 astrocyte activation involved in immune response (GO:0002265) 4 2 .40 + 5.06 9.51E-02 8.63E-01 establishment of blood-retinal barrier (GO:1990963) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of response to drug (GO:2001025) 2 1 .20 + 5.06 2.46E-01 1.00E00 viral RNA genome packaging (GO:0019074) 2 1 .20 + 5.06 2.46E-01 1.00E00 viral genome packaging (GO:0019072) 2 1 .20 + 5.06 2.46E-01 1.00E00 suppression by virus of host apoptotic process (GO:0019050) 2 1 .20 + 5.06 2.46E-01 1.00E00 neutrophil apoptotic process (GO:0001781) 4 2 .40 + 5.06 9.51E-02 8.63E-01 establishment of viral latency (GO:0019043) 2 1 .20 + 5.06 2.46E-01 1.00E00 VEGF-activated neuropilin signaling pathway (GO:0038190) 2 1 .20 + 5.06 2.46E-01 1.00E00 granulocyte colony-stimulating factor signaling pathway (GO:0038158) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of immunological synapse formation (GO:2000521) 2 1 .20 + 5.06 2.46E-01 1.00E00 synaptic transmission, glycinergic (GO:0060012) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of natural killer cell differentiation involved in immune response (GO:0032827) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of natural killer cell differentiation (GO:0032824) 2 1 .20 + 5.06 2.46E-01 1.00E00 ERBB2 signaling pathway (GO:0038128) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of retinal ganglion cell axon guidance (GO:1902336) 2 1 .20 + 5.06 2.46E-01 1.00E00 amino-acid betaine biosynthetic process (GO:0006578) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of zinc ion transmembrane transport (GO:0071583) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of zinc ion transport (GO:0071582) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of zinc ion transmembrane transport (GO:0071580) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of relaxation of cardiac muscle (GO:1901898) 2 1 .20 + 5.06 2.46E-01 1.00E00 glutamate reuptake (GO:0051935) 2 1 .20 + 5.06 2.46E-01 1.00E00 amino acid neurotransmitter reuptake (GO:0051933) 2 1 .20 + 5.06 2.46E-01 1.00E00 cellular response to mycophenolic acid (GO:0071506) 2 1 .20 + 5.06 2.46E-01 1.00E00 response to mycophenolic acid (GO:0071505) 2 1 .20 + 5.06 2.46E-01 1.00E00 endothelial cell-matrix adhesion (GO:0090673) 2 1 .20 + 5.06 2.46E-01 1.00E00 fever generation (GO:0001660) 4 2 .40 + 5.06 9.51E-02 8.62E-01 positive regulation of hematopoietic stem cell migration (GO:2000473) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of hematopoietic stem cell migration (GO:2000471) 2 1 .20 + 5.06 2.46E-01 1.00E00 uropod organization (GO:0032796) 2 1 .20 + 5.06 2.46E-01 1.00E00 Fc-epsilon receptor signaling pathway (GO:0038095) 4 2 .40 + 5.06 9.51E-02 8.62E-01 regulation of astrocyte chemotaxis (GO:2000458) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of CD8-positive, alpha-beta T cell extravasation (GO:2000451) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of macrophage migration inhibitory factor signaling pathway (GO:2000448) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of mast cell cytokine production (GO:0032764) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of eosinophil chemotaxis (GO:2000424) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of eosinophil chemotaxis (GO:2000422) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of thymocyte migration (GO:2000412) 4 2 .40 + 5.06 9.51E-02 8.61E-01 negative regulation of interleukin-5 production (GO:0032714) 4 2 .40 + 5.06 9.51E-02 8.61E-01 negative regulation of interleukin-23 production (GO:0032707) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of interleukin-4-mediated signaling pathway (GO:1902216) 2 1 .20 + 5.06 2.46E-01 1.00E00 diaphragm contraction (GO:0002086) 2 1 .20 + 5.06 2.46E-01 1.00E00 cellular response to cell-matrix adhesion (GO:0071460) 2 1 .20 + 5.06 2.46E-01 1.00E00 tyrosyl-tRNA aminoacylation (GO:0006437) 2 1 .20 + 5.06 2.46E-01 1.00E00 mitochondrial depolarization (GO:0051882) 2 1 .20 + 5.06 2.46E-01 1.00E00 desensitization of G protein-coupled receptor signaling pathway by arrestin (GO:0002032) 2 1 .20 + 5.06 2.46E-01 1.00E00 renin-angiotensin regulation of aldosterone production (GO:0002018) 2 1 .20 + 5.06 2.46E-01 1.00E00 leukotriene D4 biosynthetic process (GO:1901750) 2 1 .20 + 5.06 2.46E-01 1.00E00 renin secretion into blood stream (GO:0002001) 2 1 .20 + 5.06 2.46E-01 1.00E00 leukotriene D4 metabolic process (GO:1901748) 2 1 .20 + 5.06 2.46E-01 1.00E00 transepithelial L-ascorbic acid transport (GO:0070904) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of prostaglandin-E synthase activity (GO:2000363) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of prostaglandin-E synthase activity (GO:2000361) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of binding of sperm to zona pellucida (GO:2000360) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of hepatocyte proliferation (GO:2000346) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of blood microparticle formation (GO:2000334) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of blood microparticle formation (GO:2000332) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:1902167) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of tumor necrosis factor (ligand) superfamily member 11 production (GO:2000309) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of tumor necrosis factor (ligand) superfamily member 11 production (GO:2000307) 2 1 .20 + 5.06 2.46E-01 1.00E00 cellular response to follicle-stimulating hormone stimulus (GO:0071372) 4 2 .40 + 5.06 9.51E-02 8.60E-01 negative regulation of hair follicle development (GO:0051799) 2 1 .20 + 5.06 2.46E-01 1.00E00 cellular response to interleukin-18 (GO:0071351) 6 3 .59 + 5.06 4.04E-02 5.42E-01 regulation of hair follicle cell proliferation (GO:0071336) 2 1 .20 + 5.06 2.46E-01 1.00E00 response to iron ion starvation (GO:1990641) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of neutrophil apoptotic process (GO:0033029) 10 5 .99 + 5.06 8.16E-03 1.86E-01 activation of meiosis (GO:0090427) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of male germ cell proliferation (GO:2000256) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of long-chain fatty acid import into cell (GO:0140213) 4 2 .40 + 5.06 9.51E-02 8.60E-01 regulation of pancreatic stellate cell proliferation (GO:2000229) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of testosterone biosynthetic process (GO:2000225) 2 1 .20 + 5.06 2.46E-01 1.00E00 isopeptide cross-linking (GO:0018262) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of mitochondrial RNA catabolic process (GO:0000961) 2 1 .20 + 5.06 2.46E-01 1.00E00 cellular response to copper ion (GO:0071280) 12 6 1.19 + 5.06 3.78E-03 1.02E-01 positive regulation of germ cell proliferation (GO:1905938) 2 1 .20 + 5.06 2.46E-01 1.00E00 epinephrine uptake (GO:0051625) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of norepinephrine uptake (GO:0051621) 2 1 .20 + 5.06 2.46E-01 1.00E00 norepinephrine uptake (GO:0051620) 2 1 .20 + 5.06 2.46E-01 1.00E00 histamine uptake (GO:0051615) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of amyloid fibril formation (GO:1905908) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of anion channel activity (GO:1901529) 4 2 .40 + 5.06 9.51E-02 8.59E-01 detection of lipopolysaccharide (GO:0032497) 4 2 .40 + 5.06 9.51E-02 8.59E-01 positive regulation of sodium-dependent phosphate transport (GO:2000120) 2 1 .20 + 5.06 2.46E-01 1.00E00 deoxyinosine catabolic process (GO:0006149) 2 1 .20 + 5.06 2.46E-01 1.00E00 inosine catabolic process (GO:0006148) 2 1 .20 + 5.06 2.46E-01 1.00E00 glycerophosphate shuttle (GO:0006127) 2 1 .20 + 5.06 2.46E-01 1.00E00 resolution of mitotic recombination intermediates (GO:0071140) 2 1 .20 + 5.06 2.46E-01 1.00E00 smooth endoplasmic reticulum calcium ion homeostasis (GO:0051563) 2 1 .20 + 5.06 2.46E-01 1.00E00 resolution of recombination intermediates (GO:0071139) 2 1 .20 + 5.06 2.46E-01 1.00E00 elastin metabolic process (GO:0051541) 4 2 .40 + 5.06 9.51E-02 8.58E-01 positive regulation of tetrapyrrole biosynthetic process (GO:1901465) 2 1 .20 + 5.06 2.46E-01 1.00E00 calcitonin gene-related peptide receptor signaling pathway (GO:1990408) 2 1 .20 + 5.06 2.46E-01 1.00E00 embryonic liver development (GO:1990402) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of immune complex clearance by monocytes and macrophages (GO:0090265) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of immune complex clearance by monocytes and macrophages (GO:0090264) 2 1 .20 + 5.06 2.46E-01 1.00E00 actin filament bundle distribution (GO:0070650) 2 1 .20 + 5.06 2.46E-01 1.00E00 cell-cell adhesion in response to extracellular stimulus (GO:0140039) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of glycine import across plasma membrane (GO:1900923) 2 1 .20 + 5.06 2.46E-01 1.00E00 glyoxylate cycle (GO:0006097) 2 1 .20 + 5.06 2.46E-01 1.00E00 sorbitol metabolic process (GO:0006060) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of anaphase-promoting complex-dependent catabolic process (GO:1905786) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of anaphase-promoting complex-dependent catabolic process (GO:1905784) 2 1 .20 + 5.06 2.46E-01 1.00E00 chitin catabolic process (GO:0006032) 8 4 .79 + 5.06 1.79E-02 3.24E-01 chitin metabolic process (GO:0006030) 8 4 .79 + 5.06 1.79E-02 3.24E-01 anterograde dendritic transport of messenger ribonucleoprotein complex (GO:0098964) 2 1 .20 + 5.06 2.46E-01 1.00E00 meiotic DNA recombinase assembly (GO:0000707) 2 1 .20 + 5.06 2.46E-01 1.00E00 gap junction-mediated intercellular transport (GO:1990349) 2 1 .20 + 5.06 2.46E-01 1.00E00 dendritic transport of mitochondrion (GO:0098939) 2 1 .20 + 5.06 2.46E-01 1.00E00 membrane repolarization during ventricular cardiac muscle cell action potential (GO:0098915) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of inhibitory synapse assembly (GO:1905704) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of collateral sprouting of injured axon (GO:0048694) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of collateral sprouting of injured axon (GO:0048693) 2 1 .20 + 5.06 2.46E-01 1.00E00 protein secretion by platelet (GO:0070560) 2 1 .20 + 5.06 2.46E-01 1.00E00 collateral sprouting in absence of injury (GO:0048669) 2 1 .20 + 5.06 2.46E-01 1.00E00 myoblast fate commitment (GO:0048625) 2 1 .20 + 5.06 2.46E-01 1.00E00 lipid digestion (GO:0044241) 6 3 .59 + 5.06 4.04E-02 5.41E-01 intestinal lipid absorption (GO:0098856) 4 2 .40 + 5.06 9.51E-02 8.58E-01 prolactin secretion (GO:0070459) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of heme biosynthetic process (GO:0070455) 2 1 .20 + 5.06 2.46E-01 1.00E00 protein deglycation (GO:0036525) 2 1 .20 + 5.06 2.46E-01 1.00E00 stress response to copper ion (GO:1990169) 4 2 .40 + 5.06 9.51E-02 8.57E-01 positive regulation of ephrin receptor signaling pathway (GO:1901189) 2 1 .20 + 5.06 2.46E-01 1.00E00 neural crest cell migration involved in autonomic nervous system development (GO:1901166) 4 2 .40 + 5.06 9.51E-02 8.57E-01 iron ion import across cell outer membrane (GO:0098706) 2 1 .20 + 5.06 2.46E-01 1.00E00 response to sucrose (GO:0009744) 2 1 .20 + 5.06 2.46E-01 1.00E00 insulin catabolic process (GO:1901143) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of ERK5 cascade (GO:0070376) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of fat cell proliferation (GO:0070346) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of collagen catabolic process (GO:0120158) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of synaptic vesicle docking (GO:0099148) 2 1 .20 + 5.06 2.46E-01 1.00E00 histone H3-R26 citrullination (GO:0036413) 2 1 .20 + 5.06 2.46E-01 1.00E00 acetate ester metabolic process (GO:1900619) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of NK T cell proliferation (GO:0051140) 4 2 .40 + 5.06 9.51E-02 8.56E-01 positive regulation of NK T cell activation (GO:0051135) 6 3 .59 + 5.06 4.04E-02 5.41E-01 pore formation in membrane of other organism (GO:0035915) 2 1 .20 + 5.06 2.46E-01 1.00E00 synaptic assembly at neuromuscular junction (GO:0051124) 2 1 .20 + 5.06 2.46E-01 1.00E00 cold acclimation (GO:0009631) 2 1 .20 + 5.06 2.46E-01 1.00E00 renal water absorption (GO:0070295) 2 1 .20 + 5.06 2.46E-01 1.00E00 TCR signalosome assembly (GO:0036399) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of activation-induced cell death of T cells (GO:0070237) 2 1 .20 + 5.06 2.46E-01 1.00E00 calcium export from the mitochondrion (GO:0099093) 2 1 .20 + 5.06 2.46E-01 1.00E00 Fas signaling pathway (GO:0036337) 2 1 .20 + 5.06 2.46E-01 1.00E00 hepatocyte homeostasis (GO:0036333) 2 1 .20 + 5.06 2.46E-01 1.00E00 sphingolipid translocation (GO:0099039) 4 2 .40 + 5.06 9.51E-02 8.56E-01 ceramide phosphoethanolamine biosynthetic process (GO:1905373) 2 1 .20 + 5.06 2.46E-01 1.00E00 ceramide phosphoethanolamine metabolic process (GO:1905371) 2 1 .20 + 5.06 2.46E-01 1.00E00 eosinophil fate commitment (GO:0035854) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of pentose-phosphate shunt (GO:0043456) 4 2 .40 + 5.06 9.51E-02 8.55E-01 glucocorticoid mediated signaling pathway (GO:0043402) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of macropinocytosis (GO:1905303) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of macropinocytosis (GO:1905301) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of excitatory synapse assembly (GO:1904891) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (GO:1904878) 2 1 .20 + 5.06 2.46E-01 1.00E00 iron import into the mitochondrion (GO:0048250) 2 1 .20 + 5.06 2.46E-01 1.00E00 ciliary neurotrophic factor-mediated signaling pathway (GO:0070120) 4 2 .40 + 5.06 9.51E-02 8.55E-01 dorsal root ganglion morphogenesis (GO:1904835) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter (GO:1900477) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of interleukin-6-mediated signaling pathway (GO:0070105) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of interleukin-6-mediated signaling pathway (GO:0070104) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of interleukin-6-mediated signaling pathway (GO:0070103) 4 2 .40 + 5.06 9.51E-02 8.54E-01 vesicle targeting, trans-Golgi to endosome (GO:0048203) 2 1 .20 + 5.06 2.46E-01 1.00E00 peptidoglycan metabolic process (GO:0000270) 2 1 .20 + 5.06 2.46E-01 1.00E00 ureter maturation (GO:0035799) 2 1 .20 + 5.06 2.46E-01 1.00E00 CD8-positive, alpha-beta T cell lineage commitment (GO:0043375) 2 1 .20 + 5.06 2.46E-01 1.00E00 natural killer cell degranulation (GO:0043320) 4 2 .40 + 5.06 9.51E-02 8.54E-01 cytotoxic T cell degranulation (GO:0043316) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of core promoter binding (GO:1904797) 2 1 .20 + 5.06 2.46E-01 1.00E00 response to tetrachloromethane (GO:1904772) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of myofibroblast differentiation (GO:1904761) 4 2 .40 + 5.06 9.51E-02 8.53E-01 positive regulation of myeloid dendritic cell activation (GO:0030887) 2 1 .20 + 5.06 2.46E-01 1.00E00 pyridoxal phosphate biosynthetic process (GO:0042823) 2 1 .20 + 5.06 2.46E-01 1.00E00 pyridoxal phosphate metabolic process (GO:0042822) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of granulocyte differentiation (GO:0030853) 10 5 .99 + 5.06 8.16E-03 1.86E-01 vitamin B6 biosynthetic process (GO:0042819) 2 1 .20 + 5.06 2.46E-01 1.00E00 vitamin B6 metabolic process (GO:0042816) 2 1 .20 + 5.06 2.46E-01 1.00E00 dendritic cell homeostasis (GO:0036145) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of chaperone-mediated autophagy (GO:1904715) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of chaperone-mediated autophagy (GO:1904714) 4 2 .40 + 5.06 9.51E-02 8.53E-01 memory T cell extravasation (GO:0035683) 2 1 .20 + 5.06 2.46E-01 1.00E00 TRIF-dependent toll-like receptor signaling pathway (GO:0035666) 6 3 .59 + 5.06 4.04E-02 5.40E-01 positive regulation of lysosomal protein catabolic process (GO:1905167) 2 1 .20 + 5.06 2.46E-01 1.00E00 fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development (GO:0035607) 2 1 .20 + 5.06 2.46E-01 1.00E00 peptidyl-cysteine S-trans-nitrosylation (GO:0035606) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of type B pancreatic cell proliferation (GO:1904691) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of eye pigmentation (GO:0048073) 2 1 .20 + 5.06 2.46E-01 1.00E00 progesterone secretion (GO:0042701) 2 1 .20 + 5.06 2.46E-01 1.00E00 calcium-mediated signaling using extracellular calcium source (GO:0035585) 2 1 .20 + 5.06 2.46E-01 1.00E00 histone H4-K20 demethylation (GO:0035574) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of kidney size (GO:0035564) 2 1 .20 + 5.06 2.46E-01 1.00E00 relaxation of cardiac muscle (GO:0055119) 10 5 .99 + 5.06 8.16E-03 1.86E-01 proline transmembrane transport (GO:0035524) 4 2 .40 + 5.06 9.51E-02 8.52E-01 NAD transport (GO:0043132) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of antifungal innate immune response (GO:1905036) 2 1 .20 + 5.06 2.46E-01 1.00E00 pantothenate metabolic process (GO:0015939) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of myosin light chain kinase activity (GO:0035505) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of myosin light chain kinase activity (GO:0035504) 2 1 .20 + 5.06 2.46E-01 1.00E00 lipopolysaccharide transport (GO:0015920) 2 1 .20 + 5.06 2.46E-01 1.00E00 peptidoglycan catabolic process (GO:0009253) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of axon diameter (GO:0031133) 2 1 .20 + 5.06 2.46E-01 1.00E00 L-alanine transmembrane transport (GO:1904557) 4 2 .40 + 5.06 9.51E-02 8.52E-01 endosome membrane tubulation (GO:0097750) 2 1 .20 + 5.06 2.46E-01 1.00E00 mating plug formation (GO:0042628) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of bone mineralization involved in bone maturation (GO:1900158) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of Schwann cell migration (GO:1900148) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of phospholipase A2 activity (GO:1900138) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of plasma cell differentiation (GO:1900100) 2 1 .20 + 5.06 2.46E-01 1.00E00 cadmium ion homeostasis (GO:0055073) 2 1 .20 + 5.06 2.46E-01 1.00E00 siderophore transport (GO:0015891) 2 1 .20 + 5.06 2.46E-01 1.00E00 L-ascorbic acid transmembrane transport (GO:0015882) 2 1 .20 + 5.06 2.46E-01 1.00E00 nucleobase transport (GO:0015851) 4 2 .40 + 5.06 9.51E-02 8.51E-01 histone H3-T6 phosphorylation (GO:0035408) 2 1 .20 + 5.06 2.46E-01 1.00E00 tryptophan transport (GO:0015827) 4 2 .40 + 5.06 9.51E-02 8.51E-01 phenylalanine transport (GO:0015823) 2 1 .20 + 5.06 2.46E-01 1.00E00 Golgi to plasma membrane CFTR protein transport (GO:0043000) 2 1 .20 + 5.06 2.46E-01 1.00E00 branched-chain amino acid transport (GO:0015803) 4 2 .40 + 5.06 9.51E-02 8.50E-01 xanthine catabolic process (GO:0009115) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of endothelin production (GO:1904472) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of matrix metallopeptidase secretion (GO:1904466) 4 2 .40 + 5.06 9.51E-02 8.50E-01 negative regulation of matrix metallopeptidase secretion (GO:1904465) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of plasma cell differentiation (GO:1900098) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of establishment of Sertoli cell barrier (GO:1904446) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of iron ion import across plasma membrane (GO:1904440) 2 1 .20 + 5.06 2.46E-01 1.00E00 peptidyl-lysine modification to peptidyl-hypusine (GO:0008612) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of non-membrane spanning protein tyrosine kinase activity (GO:1903995) 2 1 .20 + 5.06 2.46E-01 1.00E00 chemoattraction of axon (GO:0061642) 2 1 .20 + 5.06 2.46E-01 1.00E00 transepithelial water transport (GO:0035377) 2 1 .20 + 5.06 2.46E-01 1.00E00 heme transmembrane transport (GO:0035351) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of protein processing in phagocytic vesicle (GO:1903923) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of protein processing in phagocytic vesicle (GO:1903921) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of actin filament severing (GO:1903919) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of actin filament severing (GO:1903918) 2 1 .20 + 5.06 2.46E-01 1.00E00 phospholipase C-activating angiotensin-activated signaling pathway (GO:0086097) 2 1 .20 + 5.06 2.46E-01 1.00E00 alpha-ketoglutarate transport (GO:0015742) 2 1 .20 + 5.06 2.46E-01 1.00E00 membrane depolarization during SA node cell action potential (GO:0086046) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of saliva secretion (GO:0046878) 4 2 .40 + 5.06 9.51E-02 8.49E-01 regulation of saliva secretion (GO:0046877) 6 3 .59 + 5.06 4.04E-02 5.40E-01 membrane repolarization during cardiac muscle cell action potential (GO:0086013) 4 2 .40 + 5.06 9.51E-02 8.49E-01 detection of diacyl bacterial lipopeptide (GO:0042496) 2 1 .20 + 5.06 2.46E-01 1.00E00 detection of triacyl bacterial lipopeptide (GO:0042495) 2 1 .20 + 5.06 2.46E-01 1.00E00 receptor-mediated virion attachment to host cell (GO:0046813) 4 2 .40 + 5.06 9.51E-02 8.48E-01 nuclear migration along microtubule (GO:0030473) 4 2 .40 + 5.06 9.51E-02 8.48E-01 cholesterol storage (GO:0010878) 2 1 .20 + 5.06 2.46E-01 1.00E00 neuropeptide catabolic process (GO:0010813) 2 1 .20 + 5.06 2.46E-01 1.00E00 ganglion morphogenesis (GO:0061552) 2 1 .20 + 5.06 2.46E-01 1.00E00 basal dendrite arborization (GO:0150020) 2 1 .20 + 5.06 2.46E-01 1.00E00 basal dendrite morphogenesis (GO:0150019) 2 1 .20 + 5.06 2.46E-01 1.00E00 basal dendrite development (GO:0150018) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of iron ion transmembrane transport (GO:0034761) 2 1 .20 + 5.06 2.46E-01 1.00E00 clathrin-dependent synaptic vesicle endocytosis (GO:0150007) 2 1 .20 + 5.06 2.46E-01 1.00E00 pyroptosome complex assembly (GO:1904270) 2 1 .20 + 5.06 2.46E-01 1.00E00 spinal cord motor neuron migration (GO:0097476) 2 1 .20 + 5.06 2.46E-01 1.00E00 motor neuron migration (GO:0097475) 4 2 .40 + 5.06 9.51E-02 8.47E-01 positive regulation of iron ion transport (GO:0034758) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of polynucleotide adenylyltransferase activity (GO:1904245) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of nitric oxide mediated signal transduction (GO:0010751) 2 1 .20 + 5.06 2.46E-01 1.00E00 synaptic vesicle lumen acidification (GO:0097401) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of long-chain fatty acid import across plasma membrane (GO:0010748) 4 2 .40 + 5.06 9.51E-02 8.47E-01 detection of fungus (GO:0016046) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of extracellular matrix disassembly (GO:0010716) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of collagen catabolic process (GO:0010710) 4 2 .40 + 5.06 9.51E-02 8.46E-01 endocardial cushion cell differentiation (GO:0061443) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of potassium ion export across plasma membrane (GO:1903765) 2 1 .20 + 5.06 2.46E-01 1.00E00 MDA-5 signaling pathway (GO:0039530) 2 1 .20 + 5.06 2.46E-01 1.00E00 cell migration involved in heart formation (GO:0060974) 2 1 .20 + 5.06 2.46E-01 1.00E00 endocardial cell differentiation (GO:0060956) 4 2 .40 + 5.06 9.51E-02 8.46E-01 mesenchymal cell proliferation involved in lung development (GO:0060916) 2 1 .20 + 5.06 2.46E-01 1.00E00 mesenchymal cell differentiation involved in lung development (GO:0060915) 2 1 .20 + 5.06 2.46E-01 1.00E00 sensory neuron axon guidance (GO:0097374) 2 1 .20 + 5.06 2.46E-01 1.00E00 adult feeding behavior (GO:0008343) 2 1 .20 + 5.06 2.46E-01 1.00E00 eosinophil differentiation (GO:0030222) 2 1 .20 + 5.06 2.46E-01 1.00E00 tarsal gland development (GO:1903699) 2 1 .20 + 5.06 2.46E-01 1.00E00 antigen processing and presentation of exogenous peptide antigen via MHC class II (GO:0019886) 16 8 1.58 + 5.06 8.33E-04 3.12E-02 cerebellum vasculature development (GO:0061300) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of protein tyrosine phosphatase activity (GO:1903614) 2 1 .20 + 5.06 2.46E-01 1.00E00 heme metabolic process (GO:0042168) 30 15 2.97 + 5.06 4.90E-06 4.08E-04 heme catabolic process (GO:0042167) 4 2 .40 + 5.06 9.51E-02 8.45E-01 nitric oxide transport (GO:0030185) 2 1 .20 + 5.06 2.46E-01 1.00E00 acetylcholine metabolic process (GO:0008291) 2 1 .20 + 5.06 2.46E-01 1.00E00 cellular response to aldosterone (GO:1904045) 2 1 .20 + 5.06 2.46E-01 1.00E00 response to aldosterone (GO:1904044) 2 1 .20 + 5.06 2.46E-01 1.00E00 mitochondrial unfolded protein response (GO:0034514) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of collagen fibril organization (GO:1904027) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of G protein-coupled receptor internalization (GO:1904022) 2 1 .20 + 5.06 2.46E-01 1.00E00 cellular response to serotonin (GO:1904015) 2 1 .20 + 5.06 2.46E-01 1.00E00 response to serotonin (GO:1904014) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of gap junction assembly (GO:1903597) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis (GO:1903588) 4 2 .40 + 5.06 9.51E-02 8.45E-01 response to anisomycin (GO:0072739) 2 1 .20 + 5.06 2.46E-01 1.00E00 prostate gland stromal morphogenesis (GO:0060741) 2 1 .20 + 5.06 2.46E-01 1.00E00 vacuolar transmembrane transport (GO:0034486) 2 1 .20 + 5.06 2.46E-01 1.00E00 intestinal epithelial structure maintenance (GO:0060729) 2 1 .20 + 5.06 2.46E-01 1.00E00 pilomotor reflex (GO:0097195) 2 1 .20 + 5.06 2.46E-01 1.00E00 syncytiotrophoblast cell differentiation involved in labyrinthine layer development (GO:0060715) 2 1 .20 + 5.06 2.46E-01 1.00E00 mesenchymal cell apoptotic process (GO:0097152) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction (GO:0014853) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction (GO:0014852) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of myeloid leukocyte mediated immunity (GO:0002887) 10 5 .99 + 5.06 8.16E-03 1.85E-01 regulation of chronic inflammatory response to non-antigenic stimulus (GO:0002880) 2 1 .20 + 5.06 2.46E-01 1.00E00 esophagus smooth muscle contraction (GO:0014846) 2 1 .20 + 5.06 2.46E-01 1.00E00 guanylate kinase-associated protein clustering (GO:0097117) 2 1 .20 + 5.06 2.46E-01 1.00E00 NMDA glutamate receptor clustering (GO:0097114) 4 2 .40 + 5.06 9.51E-02 8.44E-01 positive regulation of mitotic cell cycle, embryonic (GO:0045977) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of dopamine metabolic process (GO:0045963) 4 2 .40 + 5.06 9.51E-02 8.44E-01 positive regulation of complement activation (GO:0045917) 4 2 .40 + 5.06 9.51E-02 8.43E-01 seminal vesicle development (GO:0061107) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of constitutive secretory pathway (GO:1903433) 2 1 .20 + 5.06 2.46E-01 1.00E00 cellular response to bile acid (GO:1903413) 2 1 .20 + 5.06 2.46E-01 1.00E00 response to bile acid (GO:1903412) 2 1 .20 + 5.06 2.46E-01 1.00E00 eosinophil migration (GO:0072677) 8 4 .79 + 5.06 1.79E-02 3.24E-01 positive regulation of P-type sodium:potassium-exchanging transporter activity (GO:1903408) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of phospholipid catabolic process (GO:0060697) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of cell proliferation involved in heart valve morphogenesis (GO:0003252) 2 1 .20 + 5.06 2.46E-01 1.00E00 UDP-glucuronate metabolic process (GO:0046398) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of neurofibrillary tangle assembly (GO:1902998) 2 1 .20 + 5.06 2.46E-01 1.00E00 branch elongation involved in salivary gland morphogenesis (GO:0060667) 2 1 .20 + 5.06 2.46E-01 1.00E00 fructose biosynthetic process (GO:0046370) 2 1 .20 + 5.06 2.46E-01 1.00E00 mammary gland bud morphogenesis (GO:0060648) 2 1 .20 + 5.06 2.46E-01 1.00E00 negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process (GO:1902963) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process (GO:1902962) 2 1 .20 + 5.06 2.46E-01 1.00E00 cardiac right atrium morphogenesis (GO:0003213) 2 1 .20 + 5.06 2.46E-01 1.00E00 disaccharide biosynthetic process (GO:0046351) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of early endosome to recycling endosome transport (GO:1902954) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of tau-protein kinase activity (GO:1902949) 6 3 .59 + 5.06 4.04E-02 5.39E-01 protein localization to early endosome (GO:1902946) 2 1 .20 + 5.06 2.46E-01 1.00E00 chylomicron remodeling (GO:0034371) 2 1 .20 + 5.06 2.46E-01 1.00E00 mammary gland bud formation (GO:0060615) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of voltage-gated chloride channel activity (GO:1902943) 2 1 .20 + 5.06 2.46E-01 1.00E00 regulation of voltage-gated chloride channel activity (GO:1902941) 2 1 .20 + 5.06 2.46E-01 1.00E00 innate immune response-activating signal transduction (GO:0002758) 8 4 .79 + 5.06 1.79E-02 3.23E-01 renal protein absorption (GO:0097017) 2 1 .20 + 5.06 2.46E-01 1.00E00 positive regulation of synaptic assembly at neuromuscular junction (GO:0045887) 2 1 .20 + 5.06 2.46E-01 1.00E00 facioacoustic ganglion development (GO:1903375) 2 1 .20 + 5.06 2.46E-01 1.00E00 ventricular zone neuroblast division (GO:0021847) 2 1 .20 + 5.06 2.46E-01 1.00E00 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration (GO:0021815) 4 2 .40 + 5.06 9.51E-02 8.43E-01 fibroblast growth factor receptor signaling pathway involved in mammary gland specification (GO:0060595) 2 1 .20 + 5.06 2.46E-01 1.00E00 somatic muscle development (GO:0007525) 2 1 .20 + 5.06 2.46E-01 1.00E00 coronary vein morphogenesis (GO:0003169) 2 1 .20 + 5.06 2.46E-01 1.00E00 bundle of His development (GO:0003166) 2 1 .20 + 5.06 2.46E-01 1.00E00 cell fate specification involved in pattern specification (GO:0060573) 2 1 .20 + 5.06 2.46E-01 1.00E00 mesodermal cell fate specification (GO:0007501) 2 1 .20 + 5.06 2.46E-01 1.00E00 phenylpropanoid catabolic process (GO:0046271) 2 1 .20 + 5.06 2.46E-01 1.00E00 diaphragm development (GO:0060539) 2 1 .20 + 5.06 2.46E-01 1.00E00 response to disaccharide (GO:0034285) 2 1 .20 + 5.06 2.46E-01 1.00E00 prostate epithelial cord elongation (GO:0060523) 2 1 .20 + 5.06 2.46E-01 1.00E00 coumarin catabolic process (GO:0046226) 2 1 .20 + 5.06 2.46E-01 1.00E00 heme biosynthetic process (GO:0006783) 22 11 2.18 + 5.06 9.04E-05 4.71E-03 negative regulation of amino acid transport (GO:0051956) 14 7 1.38 + 5.06 1.77E-03 5.59E-02 phagocytosis, engulfment (GO:0006911) 97 47 9.59 + 4.90 1.34E-15 5.66E-13 antibacterial humoral response (GO:0019731) 31 15 3.07 + 4.89 6.66E-06 5.41E-04 complement activation, classical pathway (GO:0006958) 77 37 7.61 + 4.86 1.72E-12 4.28E-10 positive regulation of myeloid leukocyte mediated immunity (GO:0002888) 25 12 2.47 + 4.85 5.91E-05 3.40E-03 macrophage differentiation (GO:0030225) 23 11 2.27 + 4.84 1.23E-04 6.19E-03 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II (GO:0002504) 19 9 1.88 + 4.79 5.37E-04 2.20E-02 regulation of phagocytosis, engulfment (GO:0060099) 19 9 1.88 + 4.79 5.37E-04 2.19E-02 complement activation (GO:0006956) 85 40 8.40 + 4.76 3.66E-13 1.01E-10 B cell receptor signaling pathway (GO:0050853) 94 44 9.29 + 4.73 2.81E-14 9.08E-12 humoral immune response mediated by circulating immunoglobulin (GO:0002455) 80 37 7.91 + 4.68 4.16E-12 9.57E-10 regulation of neuroinflammatory response (GO:0150077) 26 12 2.57 + 4.67 7.93E-05 4.31E-03 positive regulation of superoxide anion generation (GO:0032930) 22 10 2.18 + 4.60 3.43E-04 1.48E-02 cellular response to interferon-alpha (GO:0035457) 11 5 1.09 + 4.60 1.10E-02 2.34E-01 positive regulation of macrophage derived foam cell differentiation (GO:0010744) 11 5 1.09 + 4.60 1.10E-02 2.34E-01 positive regulation of acute inflammatory response to antigenic stimulus (GO:0002866) 11 5 1.09 + 4.60 1.10E-02 2.34E-01 plasma membrane invagination (GO:0099024) 106 48 10.48 + 4.58 5.11E-15 1.89E-12 tetrapyrrole metabolic process (GO:0033013) 42 19 4.15 + 4.58 8.95E-07 8.94E-05 neutrophil mediated immunity (GO:0002446) 20 9 1.98 + 4.55 7.17E-04 2.79E-02 regulation of membrane invagination (GO:1905153) 20 9 1.98 + 4.55 7.17E-04 2.78E-02 defense response to fungus (GO:0050832) 29 13 2.87 + 4.53 5.09E-05 3.01E-03 neutrophil activation involved in immune response (GO:0002283) 9 4 .89 + 4.50 2.41E-02 3.91E-01 diet induced thermogenesis (GO:0002024) 9 4 .89 + 4.50 2.41E-02 3.90E-01 neuron projection maintenance (GO:1990535) 9 4 .89 + 4.50 2.41E-02 3.90E-01 extracellular vesicle biogenesis (GO:0140112) 9 4 .89 + 4.50 2.41E-02 3.89E-01 regulation of phospholipase A2 activity (GO:0032429) 9 4 .89 + 4.50 2.41E-02 3.89E-01 negative regulation of macrophage migration (GO:1905522) 9 4 .89 + 4.50 2.41E-02 3.89E-01 antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) 9 4 .89 + 4.50 2.41E-02 3.88E-01 antifungal humoral response (GO:0019732) 9 4 .89 + 4.50 2.41E-02 3.88E-01 multicellular organismal iron ion homeostasis (GO:0060586) 9 4 .89 + 4.50 2.41E-02 3.87E-01 cytokine production involved in immune response (GO:0002367) 16 7 1.58 + 4.42 3.17E-03 8.99E-02 positive regulation of phagocytosis, engulfment (GO:0060100) 16 7 1.58 + 4.42 3.17E-03 8.97E-02 killing of cells in other organism involved in symbiotic interaction (GO:0051883) 16 7 1.58 + 4.42 3.17E-03 8.95E-02 positive regulation of membrane invagination (GO:1905155) 16 7 1.58 + 4.42 3.17E-03 8.94E-02 membrane invagination (GO:0010324) 112 49 11.07 + 4.42 7.60E-15 2.68E-12 microglial cell activation (GO:0001774) 30 13 2.97 + 4.38 6.70E-05 3.75E-03 neutrophil activation (GO:0042119) 21 9 2.08 + 4.33 9.43E-04 3.45E-02 regulation of potassium ion import (GO:1903286) 7 3 .69 + 4.33 5.39E-02 6.42E-01 respiratory burst (GO:0045730) 14 6 1.38 + 4.33 6.74E-03 1.60E-01 positive regulation of toll-like receptor 9 signaling pathway (GO:0034165) 7 3 .69 + 4.33 5.39E-02 6.41E-01 positive regulation of T-helper 1 cell differentiation (GO:0045627) 7 3 .69 + 4.33 5.39E-02 6.41E-01 regulation of chloride transport (GO:2001225) 7 3 .69 + 4.33 5.39E-02 6.40E-01 natural killer cell activation involved in immune response (GO:0002323) 7 3 .69 + 4.33 5.39E-02 6.40E-01 regulation of dendritic cell apoptotic process (GO:2000668) 7 3 .69 + 4.33 5.39E-02 6.39E-01 regulation of interleukin-1-mediated signaling pathway (GO:2000659) 7 3 .69 + 4.33 5.39E-02 6.39E-01 wound healing involved in inflammatory response (GO:0002246) 7 3 .69 + 4.33 5.39E-02 6.38E-01 innate immune response activating cell surface receptor signaling pathway (GO:0002220) 7 3 .69 + 4.33 5.39E-02 6.38E-01 positive regulation of dendritic cell chemotaxis (GO:2000510) 7 3 .69 + 4.33 5.39E-02 6.37E-01 positive regulation of apoptotic process involved in morphogenesis (GO:1902339) 7 3 .69 + 4.33 5.39E-02 6.37E-01 regulation of apoptotic cell clearance (GO:2000425) 7 3 .69 + 4.33 5.39E-02 6.36E-01 cellular response to hydroperoxide (GO:0071447) 7 3 .69 + 4.33 5.39E-02 6.36E-01 cellular response to zinc ion (GO:0071294) 7 3 .69 + 4.33 5.39E-02 6.35E-01 regulation of calcium ion import across plasma membrane (GO:1905664) 7 3 .69 + 4.33 5.39E-02 6.35E-01 negative regulation of inclusion body assembly (GO:0090084) 7 3 .69 + 4.33 5.39E-02 6.34E-01 eosinophil chemotaxis (GO:0048245) 7 3 .69 + 4.33 5.39E-02 6.34E-01 positive regulation of apoptotic process involved in development (GO:1904747) 7 3 .69 + 4.33 5.39E-02 6.33E-01 membrane protein intracellular domain proteolysis (GO:0031293) 7 3 .69 + 4.33 5.39E-02 6.33E-01 extracellular exosome biogenesis (GO:0097734) 7 3 .69 + 4.33 5.39E-02 6.32E-01 regulation of matrix metallopeptidase secretion (GO:1904464) 7 3 .69 + 4.33 5.39E-02 6.32E-01 hemoglobin biosynthetic process (GO:0042541) 7 3 .69 + 4.33 5.39E-02 6.31E-01 positive regulation of cholesterol storage (GO:0010886) 7 3 .69 + 4.33 5.39E-02 6.31E-01 hepatocyte apoptotic process (GO:0097284) 14 6 1.38 + 4.33 6.74E-03 1.60E-01 vascular endothelial growth factor production (GO:0010573) 7 3 .69 + 4.33 5.39E-02 6.30E-01 phagocytosis (GO:0006909) 188 80 18.59 + 4.30 8.01E-23 6.75E-20 regulation of superoxide anion generation (GO:0032928) 26 11 2.57 + 4.28 2.85E-04 1.29E-02 regulation of monocyte chemotaxis (GO:0090025) 26 11 2.57 + 4.28 2.85E-04 1.28E-02 acute-phase response (GO:0006953) 19 8 1.88 + 4.26 1.97E-03 6.10E-02 leukotriene metabolic process (GO:0006691) 19 8 1.88 + 4.26 1.97E-03 6.09E-02 leukotriene biosynthetic process (GO:0019370) 12 5 1.19 + 4.21 1.45E-02 2.75E-01 innate immune response in mucosa (GO:0002227) 12 5 1.19 + 4.21 1.45E-02 2.75E-01 positive regulation of chemokine (C-X-C motif) ligand 2 production (GO:2000343) 12 5 1.19 + 4.21 1.45E-02 2.75E-01 neutrophil homeostasis (GO:0001780) 17 7 1.68 + 4.16 4.14E-03 1.08E-01 regulation of acute inflammatory response to antigenic stimulus (GO:0002864) 17 7 1.68 + 4.16 4.14E-03 1.08E-01 antigen processing and presentation of exogenous peptide antigen (GO:0002478) 27 11 2.67 + 4.12 3.69E-04 1.58E-02 regulation of superoxide metabolic process (GO:0090322) 32 13 3.16 + 4.11 1.13E-04 5.77E-03 cellular response to amyloid-beta (GO:1904646) 32 13 3.16 + 4.11 1.13E-04 5.75E-03 granulocyte migration (GO:0097530) 74 30 7.32 + 4.10 5.13E-09 8.20E-07 defense response to bacterium (GO:0042742) 228 92 22.54 + 4.08 9.09E-25 1.06E-21 negative regulation of chronic inflammatory response (GO:0002677) 5 2 .49 + 4.05 1.25E-01 9.87E-01 positive regulation of dendritic cell antigen processing and presentation (GO:0002606) 5 2 .49 + 4.05 1.25E-01 9.87E-01 positive regulation of oxidative stress-induced neuron death (GO:1903223) 10 4 .99 + 4.05 3.14E-02 4.63E-01 ammonium transmembrane transport (GO:0072488) 5 2 .49 + 4.05 1.25E-01 9.86E-01 regulation of toll-like receptor 9 signaling pathway (GO:0034163) 10 4 .99 + 4.05 3.14E-02 4.62E-01 purine deoxyribonucleoside metabolic process (GO:0046122) 5 2 .49 + 4.05 1.25E-01 9.86E-01 deoxyribonucleoside catabolic process (GO:0046121) 5 2 .49 + 4.05 1.25E-01 9.85E-01 positive regulation of toll-like receptor 7 signaling pathway (GO:0034157) 5 2 .49 + 4.05 1.25E-01 9.85E-01 regulation of toll-like receptor 7 signaling pathway (GO:0034155) 5 2 .49 + 4.05 1.25E-01 9.84E-01 nucleobase catabolic process (GO:0046113) 5 2 .49 + 4.05 1.25E-01 9.84E-01 toll-like receptor 2 signaling pathway (GO:0034134) 5 2 .49 + 4.05 1.25E-01 9.83E-01 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II (GO:0002580) 5 2 .49 + 4.05 1.25E-01 9.83E-01 negative regulation of dopamine secretion (GO:0033602) 5 2 .49 + 4.05 1.25E-01 9.82E-01 GMP catabolic process (GO:0046038) 5 2 .49 + 4.05 1.25E-01 9.82E-01 glutamine transport (GO:0006868) 5 2 .49 + 4.05 1.25E-01 9.81E-01 T cell antigen processing and presentation (GO:0002457) 5 2 .49 + 4.05 1.25E-01 9.81E-01 positive regulation of unsaturated fatty acid biosynthetic process (GO:2001280) 10 4 .99 + 4.05 3.14E-02 4.62E-01 positive regulation of respiratory burst (GO:0060267) 5 2 .49 + 4.05 1.25E-01 9.80E-01 negative regulation of neutrophil activation (GO:1902564) 5 2 .49 + 4.05 1.25E-01 9.80E-01 glomerular mesangium development (GO:0072109) 5 2 .49 + 4.05 1.25E-01 9.79E-01 negative regulation of chemokine (C-C motif) ligand 5 production (GO:0071650) 5 2 .49 + 4.05 1.25E-01 9.79E-01 tryptophan catabolic process (GO:0006569) 5 2 .49 + 4.05 1.25E-01 9.78E-01 negative regulation of amine transport (GO:0051953) 25 10 2.47 + 4.05 7.61E-04 2.91E-02 negative regulation of CREB transcription factor activity (GO:0032792) 5 2 .49 + 4.05 1.25E-01 9.78E-01 regulation of mast cell cytokine production (GO:0032763) 5 2 .49 + 4.05 1.25E-01 9.77E-01 apoptotic process involved in blood vessel morphogenesis (GO:1902262) 5 2 .49 + 4.05 1.25E-01 9.77E-01 regulation of eosinophil migration (GO:2000416) 5 2 .49 + 4.05 1.25E-01 9.76E-01 regulation of thymocyte migration (GO:2000410) 5 2 .49 + 4.05 1.25E-01 9.76E-01 positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) 10 4 .99 + 4.05 3.14E-02 4.61E-01 positive regulation of T-helper 17 cell differentiation (GO:2000321) 5 2 .49 + 4.05 1.25E-01 9.75E-01 regulation of superoxide dismutase activity (GO:1901668) 5 2 .49 + 4.05 1.25E-01 9.75E-01 negative regulation of immature T cell proliferation (GO:0033087) 5 2 .49 + 4.05 1.25E-01 9.74E-01 positive regulation of neutrophil apoptotic process (GO:0033031) 5 2 .49 + 4.05 1.25E-01 9.74E-01 tetrapyrrole catabolic process (GO:0033015) 5 2 .49 + 4.05 1.25E-01 9.73E-01 positive regulation of flagellated sperm motility (GO:1902093) 5 2 .49 + 4.05 1.25E-01 9.73E-01 cardiac muscle cell membrane repolarization (GO:0099622) 5 2 .49 + 4.05 1.25E-01 9.72E-01 protein O-linked glycosylation via serine (GO:0018242) 5 2 .49 + 4.05 1.25E-01 9.72E-01 cellular response to lipoteichoic acid (GO:0071223) 10 4 .99 + 4.05 3.14E-02 4.61E-01 regulation of female gonad development (GO:2000194) 5 2 .49 + 4.05 1.25E-01 9.71E-01 positive regulation of cilium-dependent cell motility (GO:2000155) 5 2 .49 + 4.05 1.25E-01 9.71E-01 regulation of removal of superoxide radicals (GO:2000121) 5 2 .49 + 4.05 1.25E-01 9.70E-01 AMP catabolic process (GO:0006196) 5 2 .49 + 4.05 1.25E-01 9.70E-01 positive regulation of phospholipase A2 activity (GO:0032430) 5 2 .49 + 4.05 1.25E-01 9.69E-01 peptidyl-cysteine S-nitrosylation (GO:0018119) 5 2 .49 + 4.05 1.25E-01 9.69E-01 NADH oxidation (GO:0006116) 5 2 .49 + 4.05 1.25E-01 9.68E-01 response to follicle-stimulating hormone (GO:0032354) 5 2 .49 + 4.05 1.25E-01 9.68E-01 lipid transport across blood-brain barrier (GO:1990379) 5 2 .49 + 4.05 1.25E-01 9.67E-01 myoblast proliferation (GO:0051450) 5 2 .49 + 4.05 1.25E-01 9.67E-01 cadmium ion transmembrane transport (GO:0070574) 5 2 .49 + 4.05 1.25E-01 9.66E-01 regulation of vesicle docking (GO:0106020) 5 2 .49 + 4.05 1.25E-01 9.66E-01 positive regulation of calcium ion import across plasma membrane (GO:1905665) 5 2 .49 + 4.05 1.25E-01 9.65E-01 neutrophil migration (GO:1990266) 65 26 6.43 + 4.05 6.61E-08 8.88E-06 positive regulation of blood-brain barrier permeability (GO:1905605) 5 2 .49 + 4.05 1.25E-01 9.65E-01 negative regulation of protein kinase C signaling (GO:0090038) 5 2 .49 + 4.05 1.25E-01 9.64E-01 exosomal secretion (GO:1990182) 5 2 .49 + 4.05 1.25E-01 9.64E-01 response to lipoteichoic acid (GO:0070391) 10 4 .99 + 4.05 3.14E-02 4.61E-01 IRE1-mediated unfolded protein response (GO:0036498) 5 2 .49 + 4.05 1.25E-01 9.63E-01 ISG15-protein conjugation (GO:0032020) 5 2 .49 + 4.05 1.25E-01 9.63E-01 negative regulation of relaxation of muscle (GO:1901078) 5 2 .49 + 4.05 1.25E-01 9.62E-01 amyloid fibril formation (GO:1990000) 10 4 .99 + 4.05 3.14E-02 4.60E-01 positive regulation of thymocyte apoptotic process (GO:0070245) 5 2 .49 + 4.05 1.25E-01 9.62E-01 detection of virus (GO:0009597) 5 2 .49 + 4.05 1.25E-01 9.61E-01 regulation of adiponectin secretion (GO:0070163) 5 2 .49 + 4.05 1.25E-01 9.61E-01 pyruvate biosynthetic process (GO:0042866) 5 2 .49 + 4.05 1.25E-01 9.60E-01 regulation of myofibroblast differentiation (GO:1904760) 5 2 .49 + 4.05 1.25E-01 9.60E-01 positive regulation of granulocyte differentiation (GO:0030854) 10 4 .99 + 4.05 3.14E-02 4.60E-01 L-serine transport (GO:0015825) 5 2 .49 + 4.05 1.25E-01 9.59E-01 negative regulation of glial cell migration (GO:1903976) 5 2 .49 + 4.05 1.25E-01 9.59E-01 indole-containing compound catabolic process (GO:0042436) 5 2 .49 + 4.05 1.25E-01 9.59E-01 cadmium ion transport (GO:0015691) 5 2 .49 + 4.05 1.25E-01 9.58E-01 carbon dioxide transport (GO:0015670) 5 2 .49 + 4.05 1.25E-01 9.58E-01 negative regulation of plasminogen activation (GO:0010757) 5 2 .49 + 4.05 1.25E-01 9.57E-01 macrophage derived foam cell differentiation (GO:0010742) 5 2 .49 + 4.05 1.25E-01 9.57E-01 regulation of inorganic anion transmembrane transport (GO:1903795) 5 2 .49 + 4.05 1.25E-01 9.56E-01 ganglioside biosynthetic process via lactosylceramide (GO:0010706) 5 2 .49 + 4.05 1.25E-01 9.56E-01 kidney vasculature development (GO:0061440) 15 6 1.48 + 4.05 8.73E-03 1.96E-01 renal system vasculature development (GO:0061437) 15 6 1.48 + 4.05 8.73E-03 1.95E-01 axonemal central apparatus assembly (GO:1904158) 5 2 .49 + 4.05 1.25E-01 9.55E-01 neutrophil differentiation (GO:0030223) 5 2 .49 + 4.05 1.25E-01 9.55E-01 hyaluronan biosynthetic process (GO:0030213) 5 2 .49 + 4.05 1.25E-01 9.54E-01 cornified envelope assembly (GO:1903575) 5 2 .49 + 4.05 1.25E-01 9.54E-01 positive regulation of cilium movement (GO:0003353) 5 2 .49 + 4.05 1.25E-01 9.53E-01 platelet activating factor metabolic process (GO:0046469) 5 2 .49 + 4.05 1.25E-01 9.53E-01 protein repair (GO:0030091) 5 2 .49 + 4.05 1.25E-01 9.52E-01 cholesterol esterification (GO:0034435) 5 2 .49 + 4.05 1.25E-01 9.52E-01 sterol esterification (GO:0034434) 5 2 .49 + 4.05 1.25E-01 9.51E-01 steroid esterification (GO:0034433) 5 2 .49 + 4.05 1.25E-01 9.51E-01 postsynaptic density protein 95 clustering (GO:0097119) 5 2 .49 + 4.05 1.25E-01 9.50E-01 negative regulation of T-helper 1 type immune response (GO:0002826) 5 2 .49 + 4.05 1.25E-01 9.50E-01 cellular potassium ion homeostasis (GO:0030007) 10 4 .99 + 4.05 3.14E-02 4.59E-01 choline metabolic process (GO:0019695) 5 2 .49 + 4.05 1.25E-01 9.49E-01 negative regulation of catecholamine metabolic process (GO:0045914) 5 2 .49 + 4.05 1.25E-01 9.49E-01 regulation of phospholipid catabolic process (GO:0060696) 5 2 .49 + 4.05 1.25E-01 9.48E-01 endocardium morphogenesis (GO:0003160) 5 2 .49 + 4.05 1.25E-01 9.48E-01 endocardium development (GO:0003157) 10 4 .99 + 4.05 3.14E-02 4.59E-01 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060527) 5 2 .49 + 4.05 1.25E-01 9.48E-01 prostate glandular acinus morphogenesis (GO:0060526) 5 2 .49 + 4.05 1.25E-01 9.47E-01 indolalkylamine catabolic process (GO:0046218) 5 2 .49 + 4.05 1.25E-01 9.47E-01 acute inflammatory response (GO:0002526) 48 19 4.75 + 4.00 4.31E-06 3.63E-04 erythrocyte development (GO:0048821) 38 15 3.76 + 3.99 4.45E-05 2.68E-03 icosanoid biosynthetic process (GO:0046456) 28 11 2.77 + 3.97 4.73E-04 1.96E-02 negative regulation of organic acid transport (GO:0032891) 23 9 2.27 + 3.96 1.57E-03 5.15E-02 negative regulation of interleukin-10 production (GO:0032693) 18 7 1.78 + 3.93 5.31E-03 1.32E-01 brown fat cell differentiation (GO:0050873) 31 12 3.07 + 3.92 2.94E-04 1.31E-02 neutrophil chemotaxis (GO:0030593) 57 22 5.64 + 3.90 1.08E-06 1.07E-04 response to lithium ion (GO:0010226) 13 5 1.29 + 3.89 1.86E-02 3.30E-01 regulation of unsaturated fatty acid biosynthetic process (GO:2001279) 13 5 1.29 + 3.89 1.86E-02 3.30E-01 surfactant homeostasis (GO:0043129) 13 5 1.29 + 3.89 1.86E-02 3.29E-01 vasculogenesis involved in coronary vascular morphogenesis (GO:0060979) 13 5 1.29 + 3.89 1.86E-02 3.29E-01 regulation of ribonuclease activity (GO:0060700) 13 5 1.29 + 3.89 1.86E-02 3.28E-01 pigment metabolic process (GO:0042440) 47 18 4.65 + 3.87 1.10E-05 8.25E-04 response to protozoan (GO:0001562) 34 13 3.36 + 3.87 1.83E-04 8.78E-03 granulocyte chemotaxis (GO:0071621) 63 24 6.23 + 3.85 4.30E-07 4.87E-05 cellular extravasation (GO:0045123) 42 16 4.15 + 3.85 3.54E-05 2.19E-03 peptide cross-linking (GO:0018149) 21 8 2.08 + 3.85 3.24E-03 9.07E-02 aminoglycan catabolic process (GO:0006026) 21 8 2.08 + 3.85 3.24E-03 9.06E-02 response to copper ion (GO:0046688) 21 8 2.08 + 3.85 3.24E-03 9.04E-02 B cell mediated immunity (GO:0019724) 129 49 12.75 + 3.84 5.41E-13 1.47E-10 response to amyloid-beta (GO:1904645) 37 14 3.66 + 3.83 1.14E-04 5.81E-03 negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) 8 3 .79 + 3.79 6.94E-02 7.31E-01 inflammatory cell apoptotic process (GO:0006925) 8 3 .79 + 3.79 6.94E-02 7.31E-01 chronic inflammatory response (GO:0002544) 8 3 .79 + 3.79 6.94E-02 7.30E-01 actin filament reorganization (GO:0090527) 8 3 .79 + 3.79 6.94E-02 7.30E-01 interleukin-6 production (GO:0032635) 8 3 .79 + 3.79 6.94E-02 7.29E-01 interleukin-2 production (GO:0032623) 8 3 .79 + 3.79 6.94E-02 7.29E-01 negative regulation of myeloid cell apoptotic process (GO:0033033) 16 6 1.58 + 3.79 1.11E-02 2.35E-01 fructose metabolic process (GO:0006000) 8 3 .79 + 3.79 6.94E-02 7.28E-01 positive chemotaxis (GO:0050918) 16 6 1.58 + 3.79 1.11E-02 2.35E-01 regulation of NK T cell activation (GO:0051133) 8 3 .79 + 3.79 6.94E-02 7.28E-01 positive regulation of prostaglandin biosynthetic process (GO:0031394) 8 3 .79 + 3.79 6.94E-02 7.27E-01 enucleate erythrocyte differentiation (GO:0043353) 8 3 .79 + 3.79 6.94E-02 7.27E-01 CD4-positive, alpha-beta T cell cytokine production (GO:0035743) 8 3 .79 + 3.79 6.94E-02 7.26E-01 defense response to protozoan (GO:0042832) 32 12 3.16 + 3.79 3.72E-04 1.59E-02 aromatic amino acid transport (GO:0015801) 8 3 .79 + 3.79 6.94E-02 7.26E-01 negative regulation of microglial cell activation (GO:1903979) 8 3 .79 + 3.79 6.94E-02 7.25E-01 regulation of microglial cell activation (GO:1903978) 16 6 1.58 + 3.79 1.11E-02 2.35E-01 regulation of cardiac muscle cell membrane potential (GO:0086036) 8 3 .79 + 3.79 6.94E-02 7.25E-01 ammonium transport (GO:0015696) 8 3 .79 + 3.79 6.94E-02 7.24E-01 positive regulation of neuroinflammatory response (GO:0150078) 8 3 .79 + 3.79 6.94E-02 7.24E-01 regulation of Schwann cell proliferation (GO:0010624) 8 3 .79 + 3.79 6.94E-02 7.23E-01 dichotomous subdivision of an epithelial terminal unit (GO:0060600) 8 3 .79 + 3.79 6.94E-02 7.23E-01 prostate glandular acinus development (GO:0060525) 8 3 .79 + 3.79 6.94E-02 7.22E-01 killing of cells of other organism (GO:0031640) 35 13 3.46 + 3.76 2.31E-04 1.08E-02 immunoglobulin mediated immune response (GO:0016064) 124 46 12.26 + 3.75 5.38E-12 1.20E-09 regulation of antigen processing and presentation (GO:0002577) 19 7 1.88 + 3.73 6.71E-03 1.60E-01 regulation of granulocyte differentiation (GO:0030852) 19 7 1.88 + 3.73 6.71E-03 1.59E-01 response to cadmium ion (GO:0046686) 30 11 2.97 + 3.71 7.54E-04 2.91E-02 response to fungus (GO:0009620) 41 15 4.05 + 3.70 8.95E-05 4.68E-03 immune response-regulating signaling pathway (GO:0002764) 200 73 19.77 + 3.69 6.13E-18 3.58E-15 positive regulation of leukocyte tethering or rolling (GO:1903238) 11 4 1.09 + 3.68 3.98E-02 5.47E-01 negative regulation of heterotypic cell-cell adhesion (GO:0034115) 11 4 1.09 + 3.68 3.98E-02 5.46E-01 regulation of T-helper 1 cell differentiation (GO:0045625) 11 4 1.09 + 3.68 3.98E-02 5.46E-01 T cell cytokine production (GO:0002369) 11 4 1.09 + 3.68 3.98E-02 5.45E-01 negative regulation of mast cell activation (GO:0033004) 11 4 1.09 + 3.68 3.98E-02 5.45E-01 detection of molecule of bacterial origin (GO:0032490) 11 4 1.09 + 3.68 3.98E-02 5.44E-01 regulation of cell-cell adhesion involved in gastrulation (GO:0070587) 11 4 1.09 + 3.68 3.98E-02 5.44E-01 response to magnesium ion (GO:0032026) 11 4 1.09 + 3.68 3.98E-02 5.44E-01 glucosamine-containing compound catabolic process (GO:1901072) 11 4 1.09 + 3.68 3.98E-02 5.43E-01 renal absorption (GO:0070293) 11 4 1.09 + 3.68 3.98E-02 5.43E-01 regulation of prostaglandin biosynthetic process (GO:0031392) 11 4 1.09 + 3.68 3.98E-02 5.42E-01 negative regulation of leukocyte degranulation (GO:0043301) 11 4 1.09 + 3.68 3.98E-02 5.42E-01 negative regulation of long-term synaptic potentiation (GO:1900272) 11 4 1.09 + 3.68 3.98E-02 5.41E-01 cellular chloride ion homeostasis (GO:0030644) 11 4 1.09 + 3.68 3.98E-02 5.41E-01 liver regeneration (GO:0097421) 11 4 1.09 + 3.68 3.98E-02 5.40E-01 positive regulation of macrophage cytokine production (GO:0060907) 11 4 1.09 + 3.68 3.98E-02 5.40E-01 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis (GO:1903587) 11 4 1.09 + 3.68 3.98E-02 5.39E-01 pigment biosynthetic process (GO:0046148) 36 13 3.56 + 3.65 2.89E-04 1.30E-02 immune response-regulating cell surface receptor signaling pathway (GO:0002768) 197 71 19.48 + 3.65 3.03E-17 1.58E-14 granulocyte activation (GO:0036230) 25 9 2.47 + 3.64 2.49E-03 7.47E-02 humoral immune response (GO:0006959) 170 61 16.81 + 3.63 6.28E-15 2.27E-12 regulation of leukocyte tethering or rolling (GO:1903236) 14 5 1.38 + 3.61 2.34E-02 3.86E-01 glomerulus vasculature development (GO:0072012) 14 5 1.38 + 3.61 2.34E-02 3.85E-01 response to hydroperoxide (GO:0033194) 14 5 1.38 + 3.61 2.34E-02 3.85E-01 actin filament capping (GO:0051693) 28 10 2.77 + 3.61 1.53E-03 5.10E-02 regulation of cholesterol storage (GO:0010885) 14 5 1.38 + 3.61 2.34E-02 3.84E-01 quaternary ammonium group transport (GO:0015697) 14 5 1.38 + 3.61 2.34E-02 3.84E-01 regulation of T-helper 1 type immune response (GO:0002825) 28 10 2.77 + 3.61 1.53E-03 5.09E-02 inflammatory response to antigenic stimulus (GO:0002437) 31 11 3.07 + 3.59 9.40E-04 3.44E-02 immune response-activating signal transduction (GO:0002757) 186 66 18.39 + 3.59 7.49E-16 3.25E-13 prostaglandin biosynthetic process (GO:0001516) 17 6 1.68 + 3.57 1.39E-02 2.69E-01 regulation of chemokine (C-X-C motif) ligand 2 production (GO:2000341) 17 6 1.68 + 3.57 1.39E-02 2.69E-01 astrocyte activation (GO:0048143) 17 6 1.68 + 3.57 1.39E-02 2.69E-01 copper ion homeostasis (GO:0055070) 17 6 1.68 + 3.57 1.39E-02 2.68E-01 prostanoid biosynthetic process (GO:0046457) 17 6 1.68 + 3.57 1.39E-02 2.68E-01 positive regulation of T-helper 1 type immune response (GO:0002827) 17 6 1.68 + 3.57 1.39E-02 2.68E-01 defense response to Gram-negative bacterium (GO:0050829) 54 19 5.34 + 3.56 1.68E-05 1.14E-03 immune response-activating cell surface receptor signaling pathway (GO:0002429) 185 65 18.29 + 3.55 1.83E-15 7.31E-13 positive regulation of T-helper cell differentiation (GO:0045624) 20 7 1.98 + 3.54 8.37E-03 1.89E-01 cellular response to cadmium ion (GO:0071276) 20 7 1.98 + 3.54 8.37E-03 1.89E-01 leukocyte migration involved in inflammatory response (GO:0002523) 23 8 2.27 + 3.52 5.07E-03 1.27E-01 response to interferon-alpha (GO:0035455) 23 8 2.27 + 3.52 5.07E-03 1.27E-01 lymphocyte mediated immunity (GO:0002449) 175 60 17.30 + 3.47 5.40E-14 1.67E-11 myeloid leukocyte migration (GO:0097529) 98 33 9.69 + 3.41 3.62E-08 5.09E-06 antigen receptor-mediated signaling pathway (GO:0050851) 164 55 16.21 + 3.39 1.26E-12 3.35E-10 respiratory burst involved in defense response (GO:0002679) 6 2 .59 + 3.37 1.58E-01 1.00E00 positive regulation of acute inflammatory response (GO:0002675) 27 9 2.67 + 3.37 3.80E-03 1.02E-01 negative regulation of immunoglobulin production (GO:0002638) 12 4 1.19 + 3.37 4.94E-02 6.05E-01 negative regulation of leukocyte tethering or rolling (GO:1903237) 3 1 .30 + 3.37 3.14E-01 1.00E00 tryptophan catabolic process to kynurenine (GO:0019441) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of endodermal cell differentiation (GO:1903225) 3 1 .30 + 3.37 3.14E-01 1.00E00 alditol catabolic process (GO:0019405) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of AMPA receptor activity (GO:2000969) 6 2 .59 + 3.37 1.58E-01 1.00E00 lung lobe morphogenesis (GO:0060463) 6 2 .59 + 3.37 1.58E-01 1.00E00 lung lobe development (GO:0060462) 6 2 .59 + 3.37 1.58E-01 1.00E00 response to intra-S DNA damage checkpoint signaling (GO:0072429) 3 1 .30 + 3.37 3.14E-01 1.00E00 dichotomous subdivision of terminal units involved in lung branching (GO:0060448) 3 1 .30 + 3.37 3.14E-01 1.00E00 involuntary skeletal muscle contraction (GO:0003011) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response (GO:0006990) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of toll-like receptor 9 signaling pathway (GO:0034164) 3 1 .30 + 3.37 3.14E-01 1.00E00 toll-like receptor 9 signaling pathway (GO:0034162) 6 2 .59 + 3.37 1.58E-01 1.00E00 cellular defense response (GO:0006968) 12 4 1.19 + 3.37 4.94E-02 6.05E-01 xanthine metabolic process (GO:0046110) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of homotypic cell-cell adhesion (GO:0034112) 9 3 .89 + 3.37 8.65E-02 8.37E-01 wax metabolic process (GO:0010166) 3 1 .30 + 3.37 3.14E-01 1.00E00 serotonin secretion by platelet (GO:0002554) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0071930) 3 1 .30 + 3.37 3.14E-01 1.00E00 monocyte chemotaxis (GO:0002548) 21 7 2.08 + 3.37 1.03E-02 2.24E-01 arachidonic acid metabolite production involved in inflammatory response (GO:0002538) 3 1 .30 + 3.37 3.14E-01 1.00E00 urea transmembrane transport (GO:0071918) 3 1 .30 + 3.37 3.14E-01 1.00E00 leukocyte migration involved in immune response (GO:0002522) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of monocyte differentiation (GO:0045657) 9 3 .89 + 3.37 8.65E-02 8.37E-01 negative regulation of megakaryocyte differentiation (GO:0045653) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of macrophage differentiation (GO:0045651) 15 5 1.48 + 3.37 2.89E-02 4.41E-01 negative regulation of macrophage differentiation (GO:0045650) 6 2 .59 + 3.37 1.58E-01 1.00E00 regulation of macrophage differentiation (GO:0045649) 21 7 2.08 + 3.37 1.03E-02 2.24E-01 positive regulation of dopamine biosynthetic process (GO:1903181) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation by symbiont of host apoptotic process (GO:0033668) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of dopamine biosynthetic process (GO:1903179) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of T-helper 2 cell differentiation (GO:0045629) 6 2 .59 + 3.37 1.58E-01 1.00E00 negative regulation of T-helper 1 cell differentiation (GO:0045626) 3 1 .30 + 3.37 3.14E-01 1.00E00 cerebellar granular layer morphogenesis (GO:0021683) 9 3 .89 + 3.37 8.65E-02 8.36E-01 lipoxin A4 biosynthetic process (GO:2001303) 3 1 .30 + 3.37 3.14E-01 1.00E00 lipoxin A4 metabolic process (GO:2001302) 3 1 .30 + 3.37 3.14E-01 1.00E00 integrin activation (GO:0033622) 9 3 .89 + 3.37 8.65E-02 8.35E-01 zygotic determination of anterior/posterior axis, embryo (GO:0007354) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of mitochondrial transcription (GO:1903109) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of mast cell differentiation (GO:0060376) 3 1 .30 + 3.37 3.14E-01 1.00E00 deoxyadenosine metabolic process (GO:0046090) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of testosterone secretion (GO:2000843) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of cell adhesion molecule production (GO:0060354) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of steroid hormone secretion (GO:2000833) 6 2 .59 + 3.37 1.58E-01 1.00E00 regulation of grooming behavior (GO:2000821) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of axon guidance (GO:1902669) 3 1 .30 + 3.37 3.14E-01 1.00E00 dAMP catabolic process (GO:0046059) 3 1 .30 + 3.37 3.14E-01 1.00E00 dGMP catabolic process (GO:0046055) 6 2 .59 + 3.37 1.58E-01 1.00E00 dAMP metabolic process (GO:0046053) 3 1 .30 + 3.37 3.14E-01 1.00E00 water transport (GO:0006833) 9 3 .89 + 3.37 8.65E-02 8.35E-01 positive regulation of caveolin-mediated endocytosis (GO:2001288) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (GO:2001268) 6 2 .59 + 3.37 1.58E-01 1.00E00 wax biosynthetic process (GO:0010025) 3 1 .30 + 3.37 3.14E-01 1.00E00 myeloid dendritic cell chemotaxis (GO:0002408) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001240) 27 9 2.67 + 3.37 3.80E-03 1.02E-01 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure (GO:0001999) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of systemic arterial blood pressure by norepinephrine-epinephrine (GO:0001993) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of systemic arterial blood pressure by circulatory renin-angiotensin (GO:0001991) 6 2 .59 + 3.37 1.58E-01 1.00E00 positive regulation of dendritic cell differentiation (GO:2001200) 3 1 .30 + 3.37 3.14E-01 1.00E00 vestibulocochlear nerve development (GO:0021562) 6 2 .59 + 3.37 1.58E-01 1.00E00 oculomotor nerve development (GO:0021557) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of activation of membrane attack complex (GO:0001969) 3 1 .30 + 3.37 3.14E-01 1.00E00 thigmotaxis (GO:0001966) 3 1 .30 + 3.37 3.14E-01 1.00E00 nitric oxide mediated signal transduction (GO:0007263) 9 3 .89 + 3.37 8.65E-02 8.34E-01 regulation of oocyte development (GO:0060281) 3 1 .30 + 3.37 3.14E-01 1.00E00 tachykinin receptor signaling pathway (GO:0007217) 6 2 .59 + 3.37 1.58E-01 1.00E00 negative regulation of hippocampal neuron apoptotic process (GO:0110091) 3 1 .30 + 3.37 3.14E-01 1.00E00 thiamine metabolic process (GO:0006772) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of G2/MI transition of meiotic cell cycle (GO:0110032) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of G2/MI transition of meiotic cell cycle (GO:0110030) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of apoptotic DNA fragmentation (GO:1902511) 3 1 .30 + 3.37 3.14E-01 1.00E00 glutathione catabolic process (GO:0006751) 6 2 .59 + 3.37 1.58E-01 1.00E00 formin-nucleated actin cable organization (GO:0110009) 3 1 .30 + 3.37 3.14E-01 1.00E00 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment (GO:0002362) 3 1 .30 + 3.37 3.14E-01 1.00E00 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation (GO:0002361) 6 2 .59 + 3.37 1.58E-01 1.00E00 androgen catabolic process (GO:0006710) 3 1 .30 + 3.37 3.14E-01 1.00E00 glucocorticoid biosynthetic process (GO:0006704) 3 1 .30 + 3.37 3.14E-01 1.00E00 cellular response to triacyl bacterial lipopeptide (GO:0071727) 3 1 .30 + 3.37 3.14E-01 1.00E00 response to triacyl bacterial lipopeptide (GO:0071725) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell (GO:2001188) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of CD8-positive, alpha-beta T cell activation (GO:2001187) 9 3 .89 + 3.37 8.65E-02 8.34E-01 pre-B cell allelic exclusion (GO:0002331) 3 1 .30 + 3.37 3.14E-01 1.00E00 CD8-positive, gamma-delta intraepithelial T cell differentiation (GO:0002305) 3 1 .30 + 3.37 3.14E-01 1.00E00 gamma-delta intraepithelial T cell differentiation (GO:0002304) 3 1 .30 + 3.37 3.14E-01 1.00E00 common-partner SMAD protein phosphorylation (GO:0007182) 6 2 .59 + 3.37 1.58E-01 1.00E00 positive regulation of epithelial cell differentiation involved in kidney development (GO:2000698) 3 1 .30 + 3.37 3.14E-01 1.00E00 glomerular mesangial cell development (GO:0072144) 3 1 .30 + 3.37 3.14E-01 1.00E00 mesangial cell development (GO:0072143) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of type IV hypersensitivity (GO:0001807) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of timing of neuron differentiation (GO:0060164) 3 1 .30 + 3.37 3.14E-01 1.00E00 glomerular mesangial cell proliferation (GO:0072110) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of thyroid hormone generation (GO:2000611) 3 1 .30 + 3.37 3.14E-01 1.00E00 deactivation of mitotic spindle assembly checkpoint (GO:1902426) 3 1 .30 + 3.37 3.14E-01 1.00E00 diacylglycerol biosynthetic process (GO:0006651) 9 3 .89 + 3.37 8.65E-02 8.33E-01 negative regulation of smooth muscle cell chemotaxis (GO:0071672) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of granzyme B production (GO:0071663) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of granzyme B production (GO:0071661) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of granulocyte colony-stimulating factor production (GO:0071657) 3 1 .30 + 3.37 3.14E-01 1.00E00 vacuolar protein processing (GO:0006624) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of macrophage inflammatory protein 1 alpha production (GO:0071640) 6 2 .59 + 3.37 1.58E-01 1.00E00 phosphocreatine metabolic process (GO:0006603) 3 1 .30 + 3.37 3.14E-01 1.00E00 response to molecule of fungal origin (GO:0002238) 6 2 .59 + 3.37 1.58E-01 1.00E00 fusion of virus membrane with host plasma membrane (GO:0019064) 3 1 .30 + 3.37 3.14E-01 1.00E00 natural killer cell proliferation (GO:0001787) 3 1 .30 + 3.37 3.14E-01 1.00E00 release from viral latency (GO:0019046) 3 1 .30 + 3.37 3.14E-01 1.00E00 latent virus replication (GO:0019045) 3 1 .30 + 3.37 3.14E-01 1.00E00 female meiosis sister chromatid cohesion (GO:0007066) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of platelet-derived growth factor receptor-beta signaling pathway (GO:2000588) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of platelet-derived growth factor receptor-beta signaling pathway (GO:2000587) 3 1 .30 + 3.37 3.14E-01 1.00E00 comma-shaped body morphogenesis (GO:0072049) 3 1 .30 + 3.37 3.14E-01 1.00E00 hair cycle phase (GO:0044851) 9 3 .89 + 3.37 8.65E-02 8.33E-01 neuropilin signaling pathway (GO:0038189) 3 1 .30 + 3.37 3.14E-01 1.00E00 protein localization to bicellular tight junction (GO:1902396) 6 2 .59 + 3.37 1.58E-01 1.00E00 glomerular mesangial cell differentiation (GO:0072008) 3 1 .30 + 3.37 3.14E-01 1.00E00 mesangial cell differentiation (GO:0072007) 3 1 .30 + 3.37 3.14E-01 1.00E00 macrophage colony-stimulating factor signaling pathway (GO:0038145) 3 1 .30 + 3.37 3.14E-01 1.00E00 phosphagen metabolic process (GO:0006599) 3 1 .30 + 3.37 3.14E-01 1.00E00 spermine biosynthetic process (GO:0006597) 3 1 .30 + 3.37 3.14E-01 1.00E00 multi-organism membrane fusion (GO:0044800) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of dendritic cell chemotaxis (GO:2000508) 9 3 .89 + 3.37 8.65E-02 8.32E-01 melanin metabolic process (GO:0006582) 9 3 .89 + 3.37 8.65E-02 8.32E-01 regulation of natural killer cell differentiation involved in immune response (GO:0032826) 3 1 .30 + 3.37 3.14E-01 1.00E00 copper ion export (GO:0060003) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of natural killer cell proliferation (GO:0032819) 6 2 .59 + 3.37 1.58E-01 1.00E00 histidine catabolic process (GO:0006548) 3 1 .30 + 3.37 3.14E-01 1.00E00 cytoplasmic translational termination (GO:0002184) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of transmission of nerve impulse (GO:0051970) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) 3 1 .30 + 3.37 3.14E-01 1.00E00 cellular response to temperature stimulus (GO:0071502) 3 1 .30 + 3.37 3.14E-01 1.00E00 T-tubule organization (GO:0033292) 6 2 .59 + 3.37 1.58E-01 1.00E00 negative regulation of mitotic spindle assembly checkpoint signaling (GO:0140499) 3 1 .30 + 3.37 3.14E-01 1.00E00 HRI-mediated signaling (GO:0140468) 3 1 .30 + 3.37 3.14E-01 1.00E00 pericentric heterochromatin organization (GO:0140462) 3 1 .30 + 3.37 3.14E-01 1.00E00 cytokine precursor processing (GO:0140447) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of CD8-positive, alpha-beta T cell extravasation (GO:2000449) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of mast cell cytokine production (GO:0032765) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of monocyte extravasation (GO:2000439) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of apoptotic cell clearance (GO:2000427) 6 2 .59 + 3.37 1.58E-01 1.00E00 apoptotic process involved in embryonic digit morphogenesis (GO:1902263) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of delayed rectifier potassium channel activity (GO:1902261) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of interleukin-17 production (GO:0032740) 18 6 1.78 + 3.37 1.72E-02 3.14E-01 negative regulation of T cell migration (GO:2000405) 6 2 .59 + 3.37 1.58E-01 1.00E00 negative regulation of interleukin-17 production (GO:0032700) 18 6 1.78 + 3.37 1.72E-02 3.14E-01 regulation of interleukin-4-mediated signaling pathway (GO:1902214) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of serotonin secretion (GO:0014064) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of gamma-aminobutyric acid secretion (GO:0014053) 3 1 .30 + 3.37 3.14E-01 1.00E00 osteoblast fate commitment (GO:0002051) 6 2 .59 + 3.37 1.58E-01 1.00E00 astrocyte development (GO:0014002) 33 11 3.26 + 3.37 1.42E-03 4.79E-02 cytolysis by host of symbiont cells (GO:0051838) 3 1 .30 + 3.37 3.14E-01 1.00E00 cell-cell signaling involved in cell fate commitment (GO:0045168) 3 1 .30 + 3.37 3.14E-01 1.00E00 cellular response to low-density lipoprotein particle stimulus (GO:0071404) 15 5 1.48 + 3.37 2.89E-02 4.41E-01 regulation of renal output by angiotensin (GO:0002019) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of angiotensin levels in blood (GO:0002002) 3 1 .30 + 3.37 3.14E-01 1.00E00 cytolysis in other organism involved in symbiotic interaction (GO:0051801) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of myoblast fusion (GO:1901740) 3 1 .30 + 3.37 3.14E-01 1.00E00 disaccharide metabolic process (GO:0005984) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of platelet aggregation (GO:1901731) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of cell proliferation involved in kidney development (GO:1901724) 9 3 .89 + 3.37 8.65E-02 8.31E-01 negative regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033140) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of interleukin-1 alpha production (GO:0032690) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of binding of sperm to zona pellucida (GO:2000359) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of chemokine (C-X-C motif) ligand 2 production (GO:2000342) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of interleukin-23 production (GO:0032667) 6 2 .59 + 3.37 1.58E-01 1.00E00 positive regulation of keratinocyte apoptotic process (GO:1902174) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of keratinocyte apoptotic process (GO:1902172) 6 2 .59 + 3.37 1.58E-01 1.00E00 regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) 12 4 1.19 + 3.37 4.94E-02 6.04E-01 positive regulation of synaptic vesicle exocytosis (GO:2000302) 3 1 .30 + 3.37 3.14E-01 1.00E00 chemokine production (GO:0032602) 6 2 .59 + 3.37 1.58E-01 1.00E00 cellular response to corticotropin-releasing hormone stimulus (GO:0071376) 3 1 .30 + 3.37 3.14E-01 1.00E00 cellular response to interleukin-15 (GO:0071350) 6 2 .59 + 3.37 1.58E-01 1.00E00 positive regulation of NAD+ ADP-ribosyltransferase activity (GO:1901666) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of NAD+ ADP-ribosyltransferase activity (GO:1901664) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of T cell differentiation in thymus (GO:0033085) 9 3 .89 + 3.37 8.65E-02 8.31E-01 glycoside transport (GO:1901656) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of nitric oxide biosynthetic process (GO:0045019) 15 5 1.48 + 3.37 2.89E-02 4.40E-01 platelet alpha granule organization (GO:0070889) 3 1 .30 + 3.37 3.14E-01 1.00E00 myeloid cell apoptotic process (GO:0033028) 6 2 .59 + 3.37 1.58E-01 1.00E00 negative regulation of mast cell apoptotic process (GO:0033026) 3 1 .30 + 3.37 3.14E-01 1.00E00 endosome fission (GO:0140285) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of bile acid biosynthetic process (GO:0070859) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of testosterone biosynthetic process (GO:2000224) 3 1 .30 + 3.37 3.14E-01 1.00E00 ventricular cardiac muscle cell membrane repolarization (GO:0099625) 3 1 .30 + 3.37 3.14E-01 1.00E00 protein O-linked glycosylation via threonine (GO:0018243) 6 2 .59 + 3.37 1.58E-01 1.00E00 regulation of NADP metabolic process (GO:1902031) 6 2 .59 + 3.37 1.58E-01 1.00E00 cellular response to lithium ion (GO:0071285) 12 4 1.19 + 3.37 4.94E-02 6.04E-01 pointed-end actin filament capping (GO:0051694) 3 1 .30 + 3.37 3.14E-01 1.00E00 cellular response to bacterial lipopeptide (GO:0071221) 6 2 .59 + 3.37 1.58E-01 1.00E00 cellular response to bacterial lipoprotein (GO:0071220) 6 2 .59 + 3.37 1.58E-01 1.00E00 protein localization to juxtaparanode region of axon (GO:0071205) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process (GO:0140199) 3 1 .30 + 3.37 3.14E-01 1.00E00 chemical homeostasis within a tissue (GO:0048875) 15 5 1.48 + 3.37 2.89E-02 4.40E-01 positive regulation of axon extension involved in axon guidance (GO:0048842) 6 2 .59 + 3.37 1.58E-01 1.00E00 regulation of progesterone biosynthetic process (GO:2000182) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of peptidyl-cysteine S-nitrosylation (GO:2000170) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of postsynaptic cytosolic calcium ion concentration (GO:0099566) 3 1 .30 + 3.37 3.14E-01 1.00E00 age-dependent response to oxidative stress (GO:0001306) 3 1 .30 + 3.37 3.14E-01 1.00E00 peptidyl-glutamine modification (GO:0018199) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation by symbiont of host programmed cell death (GO:0052041) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of cell proliferation involved in heart morphogenesis (GO:2000137) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of endocannabinoid signaling pathway (GO:2000124) 3 1 .30 + 3.37 3.14E-01 1.00E00 adhesion of symbiont to host (GO:0044406) 12 4 1.19 + 3.37 4.94E-02 6.04E-01 deoxyadenosine catabolic process (GO:0006157) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of dopamine uptake involved in synaptic transmission (GO:0051584) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of oogenesis (GO:1905879) 3 1 .30 + 3.37 3.14E-01 1.00E00 nuclear matrix anchoring at nuclear membrane (GO:0090292) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of retinal ganglion cell axon guidance (GO:0090259) 3 1 .30 + 3.37 3.14E-01 1.00E00 response to interleukin-18 (GO:0070673) 9 3 .89 + 3.37 8.65E-02 8.30E-01 positive regulation of tetrapyrrole metabolic process (GO:1901403) 3 1 .30 + 3.37 3.14E-01 1.00E00 sarcomerogenesis (GO:0048769) 3 1 .30 + 3.37 3.14E-01 1.00E00 formin-nucleated actin cable assembly (GO:0070649) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of skeletal muscle fiber development (GO:0048743) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of determination of dorsal identity (GO:2000017) 3 1 .30 + 3.37 3.14E-01 1.00E00 hexitol metabolic process (GO:0006059) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of chorionic trophoblast cell proliferation (GO:1901382) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of inhibitory synapse assembly (GO:1905702) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of odontoblast differentiation (GO:1901329) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of axon extension involved in regeneration (GO:0048691) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of axon extension involved in regeneration (GO:0048690) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of synapse maturation (GO:0090129) 9 3 .89 + 3.37 8.65E-02 8.30E-01 thermoception (GO:0050955) 3 1 .30 + 3.37 3.14E-01 1.00E00 induction of positive chemotaxis (GO:0050930) 12 4 1.19 + 3.37 4.94E-02 6.03E-01 adenosine transport (GO:0032238) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of macrophage colony-stimulating factor production (GO:1901258) 3 1 .30 + 3.37 3.14E-01 1.00E00 meiotic metaphase plate congression (GO:0051311) 3 1 .30 + 3.37 3.14E-01 1.00E00 foam cell differentiation (GO:0090077) 6 2 .59 + 3.37 1.58E-01 1.00E00 relaxation of skeletal muscle (GO:0090076) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of thrombin-activated receptor signaling pathway (GO:0070495) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of thrombin-activated receptor signaling pathway (GO:0070494) 3 1 .30 + 3.37 3.14E-01 1.00E00 monocyte aggregation (GO:0070487) 6 2 .59 + 3.37 1.58E-01 1.00E00 thyroid-stimulating hormone secretion (GO:0070460) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway (GO:0070430) 3 1 .30 + 3.37 3.14E-01 1.00E00 Peyer's patch development (GO:0048541) 12 4 1.19 + 3.37 4.94E-02 6.03E-01 mucosa-associated lymphoid tissue development (GO:0048537) 12 4 1.19 + 3.37 4.94E-02 6.02E-01 negative regulation of vascular endothelial growth factor signaling pathway (GO:1900747) 9 3 .89 + 3.37 8.65E-02 8.29E-01 positive regulation by symbiont of entry into host (GO:0075294) 9 3 .89 + 3.37 8.65E-02 8.29E-01 cellular response to nutrient (GO:0031670) 15 5 1.48 + 3.37 2.89E-02 4.39E-01 regulation of ephrin receptor signaling pathway (GO:1901187) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of lipopolysaccharide-mediated signaling pathway (GO:0031666) 9 3 .89 + 3.37 8.65E-02 8.28E-01 insulin metabolic process (GO:1901142) 9 3 .89 + 3.37 8.65E-02 8.28E-01 detection of endogenous stimulus (GO:0009726) 3 1 .30 + 3.37 3.14E-01 1.00E00 detection of bacterial lipopeptide (GO:0070340) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of phagocytosis (GO:0050766) 75 25 7.42 + 3.37 1.86E-06 1.70E-04 ventral trunk neural crest cell migration (GO:0036486) 3 1 .30 + 3.37 3.14E-01 1.00E00 response to bacterial lipopeptide (GO:0070339) 6 2 .59 + 3.37 1.58E-01 1.00E00 trunk neural crest cell migration (GO:0036484) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of retrograde trans-synaptic signaling by endocanabinoid (GO:0099178) 3 1 .30 + 3.37 3.14E-01 1.00E00 detection of muscle stretch (GO:0035995) 3 1 .30 + 3.37 3.14E-01 1.00E00 hemoglobin metabolic process (GO:0020027) 12 4 1.19 + 3.37 4.94E-02 6.02E-01 nuclear matrix organization (GO:0043578) 3 1 .30 + 3.37 3.14E-01 1.00E00 lens fiber cell apoptotic process (GO:1990086) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of myeloid progenitor cell differentiation (GO:1905453) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of signal transduction in absence of ligand (GO:1901099) 27 9 2.67 + 3.37 3.80E-03 1.02E-01 steroid hormone secretion (GO:0035929) 3 1 .30 + 3.37 3.14E-01 1.00E00 rRNA import into mitochondrion (GO:0035928) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of engulfment of apoptotic cell (GO:1901074) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of brain-derived neurotrophic factor receptor signaling pathway (GO:0031548) 3 1 .30 + 3.37 3.14E-01 1.00E00 pericentric heterochromatin assembly (GO:0031508) 3 1 .30 + 3.37 3.14E-01 1.00E00 sodium ion export across plasma membrane (GO:0036376) 9 3 .89 + 3.37 8.65E-02 8.27E-01 glial cell-derived neurotrophic factor receptor signaling pathway (GO:0035860) 3 1 .30 + 3.37 3.14E-01 1.00E00 oviduct epithelium development (GO:0035846) 3 1 .30 + 3.37 3.14E-01 1.00E00 response to corticotropin-releasing hormone (GO:0043435) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of memory T cell differentiation (GO:0043380) 6 2 .59 + 3.37 1.58E-01 1.00E00 cellular response to hepatocyte growth factor stimulus (GO:0035729) 15 5 1.48 + 3.37 2.89E-02 4.39E-01 interleukin-15-mediated signaling pathway (GO:0035723) 6 2 .59 + 3.37 1.58E-01 1.00E00 regulation of eosinophil degranulation (GO:0043309) 3 1 .30 + 3.37 3.14E-01 1.00E00 protein nitrosylation (GO:0017014) 6 2 .59 + 3.37 1.58E-01 1.00E00 negative regulation of NMDA glutamate receptor activity (GO:1904782) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of myeloid dendritic cell activation (GO:0030885) 6 2 .59 + 3.37 1.58E-01 1.00E00 behavioral response to ethanol (GO:0048149) 6 2 .59 + 3.37 1.58E-01 1.00E00 negative regulation of purine nucleotide biosynthetic process (GO:1900372) 6 2 .59 + 3.37 1.58E-01 1.00E00 phosphatidylethanolamine acyl-chain remodeling (GO:0036152) 6 2 .59 + 3.37 1.58E-01 1.00E00 histone dephosphorylation (GO:0016576) 6 2 .59 + 3.37 1.58E-01 1.00E00 negative regulation of nucleotide biosynthetic process (GO:0030809) 6 2 .59 + 3.37 1.58E-01 1.00E00 positive regulation of protein localization to phagocytic vesicle (GO:1905171) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of protein localization to phagocytic vesicle (GO:1905169) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of membrane invagination (GO:1905154) 3 1 .30 + 3.37 3.14E-01 1.00E00 thiamine-containing compound metabolic process (GO:0042723) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of astrocyte activation (GO:0061889) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of astrocyte activation (GO:0061888) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of mini excitatory postsynaptic potential (GO:0061885) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of vascular permeability (GO:0043117) 18 6 1.78 + 3.37 1.72E-02 3.14E-01 sister chromatid biorientation (GO:0031134) 3 1 .30 + 3.37 3.14E-01 1.00E00 dendrite regeneration (GO:0031104) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of intracellular mRNA localization (GO:1904582) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of glucocorticoid mediated signaling pathway (GO:1900169) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of Schwann cell migration (GO:1900149) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of Schwann cell migration (GO:1900147) 6 2 .59 + 3.37 1.58E-01 1.00E00 positive regulation of hyaluranon cable assembly (GO:1900106) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of hyaluranon cable assembly (GO:1900104) 3 1 .30 + 3.37 3.14E-01 1.00E00 protein targeting to lysosome involved in chaperone-mediated autophagy (GO:0061740) 3 1 .30 + 3.37 3.14E-01 1.00E00 anterior neural tube closure (GO:0061713) 3 1 .30 + 3.37 3.14E-01 1.00E00 response to interferon-beta (GO:0035456) 48 16 4.75 + 3.37 1.29E-04 6.42E-03 pyrimidine nucleobase transport (GO:0015855) 3 1 .30 + 3.37 3.14E-01 1.00E00 purine ribonucleoside diphosphate catabolic process (GO:0009181) 6 2 .59 + 3.37 1.58E-01 1.00E00 peptidoglycan transport (GO:0015835) 3 1 .30 + 3.37 3.14E-01 1.00E00 leucine transport (GO:0015820) 6 2 .59 + 3.37 1.58E-01 1.00E00 purine nucleoside diphosphate catabolic process (GO:0009137) 6 2 .59 + 3.37 1.58E-01 1.00E00 regulation of endothelin production (GO:1904470) 3 1 .30 + 3.37 3.14E-01 1.00E00 superoxide anion generation (GO:0042554) 12 4 1.19 + 3.37 4.94E-02 6.01E-01 regulation of establishment of Sertoli cell barrier (GO:1904444) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of iron ion import across plasma membrane (GO:1904438) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of nitric oxide metabolic process (GO:1904406) 15 5 1.48 + 3.37 2.89E-02 4.38E-01 negative regulation of calcidiol 1-monooxygenase activity (GO:0010956) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of very-low-density lipoprotein particle clearance (GO:0010916) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of very-low-density lipoprotein particle clearance (GO:0010915) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of eating behavior (GO:1903999) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of heparan sulfate proteoglycan biosynthetic process (GO:0010909) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of heparan sulfate proteoglycan biosynthetic process (GO:0010908) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of cellular response to macrophage colony-stimulating factor stimulus (GO:1903972) 6 2 .59 + 3.37 1.58E-01 1.00E00 regulation of response to macrophage colony-stimulating factor (GO:1903969) 6 2 .59 + 3.37 1.58E-01 1.00E00 negative regulation of hepatocyte apoptotic process (GO:1903944) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of hepatocyte apoptotic process (GO:1903943) 3 1 .30 + 3.37 3.14E-01 1.00E00 polyol transport (GO:0015791) 6 2 .59 + 3.37 1.58E-01 1.00E00 adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process (GO:0086023) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of neuromuscular junction development (GO:1904398) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of odontogenesis (GO:0042482) 6 2 .59 + 3.37 1.58E-01 1.00E00 regulation of protein localization to cell-cell junction (GO:0150106) 3 1 .30 + 3.37 3.14E-01 1.00E00 sequestering of iron ion (GO:0097577) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of protein catabolic process in the vacuole (GO:1904352) 3 1 .30 + 3.37 3.14E-01 1.00E00 dopamine biosynthetic process (GO:0042416) 9 3 .89 + 3.37 8.65E-02 8.27E-01 membrane fusion involved in viral entry into host cell (GO:0039663) 3 1 .30 + 3.37 3.14E-01 1.00E00 trunk segmentation (GO:0035290) 3 1 .30 + 3.37 3.14E-01 1.00E00 organic cation transport (GO:0015695) 21 7 2.08 + 3.37 1.03E-02 2.23E-01 copper ion import (GO:0015677) 6 2 .59 + 3.37 1.58E-01 1.00E00 neuron-glial cell signaling (GO:0150099) 3 1 .30 + 3.37 3.14E-01 1.00E00 glial cell-neuron signaling (GO:0150098) 3 1 .30 + 3.37 3.14E-01 1.00E00 phosphagen biosynthetic process (GO:0042396) 3 1 .30 + 3.37 3.14E-01 1.00E00 sympathetic neuron projection guidance (GO:0097491) 3 1 .30 + 3.37 3.14E-01 1.00E00 sympathetic neuron projection extension (GO:0097490) 3 1 .30 + 3.37 3.14E-01 1.00E00 L-alanine import across plasma membrane (GO:1904273) 3 1 .30 + 3.37 3.14E-01 1.00E00 fructosamine metabolic process (GO:0030389) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of bile acid metabolic process (GO:1904253) 3 1 .30 + 3.37 3.14E-01 1.00E00 pericyte cell differentiation (GO:1904238) 6 2 .59 + 3.37 1.58E-01 1.00E00 regulation of plasminogen activation (GO:0010755) 9 3 .89 + 3.37 8.65E-02 8.26E-01 negative regulation of cGMP-mediated signaling (GO:0010754) 3 1 .30 + 3.37 3.14E-01 1.00E00 cellular monovalent inorganic anion homeostasis (GO:0030320) 12 4 1.19 + 3.37 4.94E-02 6.01E-01 regulation of primitive erythrocyte differentiation (GO:0010725) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of inorganic anion transmembrane transport (GO:1903797) 3 1 .30 + 3.37 3.14E-01 1.00E00 response to mercury ion (GO:0046689) 9 3 .89 + 3.37 8.65E-02 8.25E-01 negative regulation of cholangiocyte apoptotic process (GO:1904193) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of cholangiocyte apoptotic process (GO:1904192) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of adipose tissue development (GO:1904179) 6 2 .59 + 3.37 1.58E-01 1.00E00 negative regulation of adipose tissue development (GO:1904178) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of adipose tissue development (GO:1904177) 9 3 .89 + 3.37 8.65E-02 8.25E-01 amino acid import across plasma membrane (GO:0089718) 27 9 2.67 + 3.37 3.80E-03 1.02E-01 monocyte differentiation (GO:0030224) 12 4 1.19 + 3.37 4.94E-02 6.00E-01 negative regulation of Schwann cell proliferation (GO:0010626) 6 2 .59 + 3.37 1.58E-01 1.00E00 regulation of cell adhesion involved in heart morphogenesis (GO:0061344) 3 1 .30 + 3.37 3.14E-01 1.00E00 cardiac neural crest cell development involved in outflow tract morphogenesis (GO:0061309) 6 2 .59 + 3.37 1.58E-01 1.00E00 negative regulation of DNA catabolic process (GO:1903625) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of Rac protein signal transduction (GO:0035021) 3 1 .30 + 3.37 3.14E-01 1.00E00 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800) 6 2 .59 + 3.37 1.58E-01 1.00E00 positive regulation of viral entry into host cell (GO:0046598) 9 3 .89 + 3.37 8.65E-02 8.24E-01 regulation of cell differentiation involved in embryonic placenta development (GO:0060800) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of collagen fibril organization (GO:1904028) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of collagen fibril organization (GO:1904026) 6 2 .59 + 3.37 1.58E-01 1.00E00 regulation of G protein-coupled receptor internalization (GO:1904020) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of activation of Janus kinase activity (GO:0010536) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of phospholipase activity (GO:0010519) 6 2 .59 + 3.37 1.58E-01 1.00E00 one-carbon compound transport (GO:0019755) 9 3 .89 + 3.37 8.65E-02 8.24E-01 establishment of cell polarity involved in ameboidal cell migration (GO:0003365) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of branching involved in mammary gland duct morphogenesis (GO:0060762) 3 1 .30 + 3.37 3.14E-01 1.00E00 cardiac endothelial cell differentiation (GO:0003348) 6 2 .59 + 3.37 1.58E-01 1.00E00 regulation of extracellular matrix constituent secretion (GO:0003330) 9 3 .89 + 3.37 8.65E-02 8.23E-01 positive regulation of blood pressure by epinephrine-norepinephrine (GO:0003321) 3 1 .30 + 3.37 3.14E-01 1.00E00 response to sorbitol (GO:0072708) 3 1 .30 + 3.37 3.14E-01 1.00E00 prostate gland morphogenetic growth (GO:0060737) 3 1 .30 + 3.37 3.14E-01 1.00E00 striated muscle atrophy (GO:0014891) 3 1 .30 + 3.37 3.14E-01 1.00E00 very-low-density lipoprotein particle clearance (GO:0034447) 3 1 .30 + 3.37 3.14E-01 1.00E00 intercellular transport (GO:0010496) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of hypersensitivity (GO:0002884) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of chronic inflammatory response to antigenic stimulus (GO:0002874) 3 1 .30 + 3.37 3.14E-01 1.00E00 urate biosynthetic process (GO:0034418) 3 1 .30 + 3.37 3.14E-01 1.00E00 myoblast migration involved in skeletal muscle regeneration (GO:0014839) 3 1 .30 + 3.37 3.14E-01 1.00E00 parallel actin filament bundle assembly (GO:0030046) 6 2 .59 + 3.37 1.58E-01 1.00E00 negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target (GO:0002859) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of natural killer cell mediated immune response to tumor cell (GO:0002856) 3 1 .30 + 3.37 3.14E-01 1.00E00 gamma-aminobutyric acid receptor clustering (GO:0097112) 3 1 .30 + 3.37 3.14E-01 1.00E00 negative regulation of growth rate (GO:0045967) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of chondrocyte development (GO:0061181) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of lactation (GO:1903487) 3 1 .30 + 3.37 3.14E-01 1.00E00 trachea gland development (GO:0061153) 3 1 .30 + 3.37 3.14E-01 1.00E00 trachea submucosa development (GO:0061152) 3 1 .30 + 3.37 3.14E-01 1.00E00 positive regulation of translational termination (GO:0045905) 3 1 .30 + 3.37 3.14E-01 1.00E00 pancreas morphogenesis (GO:0061113) 3 1 .30 + 3.37 3.14E-01 1.00E00 smoothened signaling pathway involved in ventral spinal cord patterning (GO:0021910) 3 1 .30 + 3.37 3.14E-01 1.00E00 mechanosensory behavior (GO:0007638) 12 4 1.19 + 3.37 4.94E-02 6.00E-01 endocardial cushion fusion (GO:0003274) 3 1 .30 + 3.37 3.14E-01 1.00E00 branching involved in labyrinthine layer morphogenesis (GO:0060670) 12 4 1.19 + 3.37 4.94E-02 5.99E-01 cardiac neural crest cell migration involved in outflow tract morphogenesis (GO:0003253) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of cell proliferation involved in heart valve morphogenesis (GO:0003250) 3 1 .30 + 3.37 3.14E-01 1.00E00 cardiac right ventricle formation (GO:0003219) 3 1 .30 + 3.37 3.14E-01 1.00E00 phosphatidylethanolamine catabolic process (GO:0046338) 3 1 .30 + 3.37 3.14E-01 1.00E00 lateral inhibition (GO:0046331) 3 1 .30 + 3.37 3.14E-01 1.00E00 phosphocreatine biosynthetic process (GO:0046314) 3 1 .30 + 3.37 3.14E-01 1.00E00 histone H3-K56 acetylation (GO:0097043) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of muscle hyperplasia (GO:0014738) 3 1 .30 + 3.37 3.14E-01 1.00E00 natural killer cell inhibitory signaling pathway (GO:0002769) 3 1 .30 + 3.37 3.14E-01 1.00E00 mature conventional dendritic cell differentiation (GO:0097029) 3 1 .30 + 3.37 3.14E-01 1.00E00 regulation of skeletal muscle contraction by calcium ion signaling (GO:0014722) 3 1 .30 + 3.37 3.14E-01 1.00E00 MyD88-dependent toll-like receptor signaling pathway (GO:0002755) 15 5 1.48 + 3.37 2.89E-02 4.38E-01 negative regulation of histone H3-K27 methylation (GO:0061086) 3 1 .30 + 3.37 3.14E-01 1.00E00 epithelial cell differentiation involved in mammary gland alveolus development (GO:0061030) 3 1 .30 + 3.37 3.14E-01 1.00E00 forebrain neuroblast division (GO:0021873) 6 2 .59 + 3.37 1.58E-01 1.00E00 hypothalamic tangential migration using cell-axon interactions (GO:0021856) 3 1 .30 + 3.37 3.14E-01 1.00E00 age-dependent general metabolic decline (GO:0007571) 3 1 .30 + 3.37 3.14E-01 1.00E00 gonadotrophin-releasing hormone neuronal migration to the hypothalamus (GO:0021828) 3 1 .30 + 3.37 3.14E-01 1.00E00 cell motility involved in cerebral cortex radial glia guided migration (GO:0021814) 6 2 .59 + 3.37 1.58E-01 1.00E00 mammary gland specification (GO:0060594) 3 1 .30 + 3.37 3.14E-01 1.00E00 His-Purkinje system development (GO:0003164) 3 1 .30 + 3.37 3.14E-01 1.00E00 T-helper 17 cell lineage commitment (GO:0072540) 9 3 .89 + 3.37 8.65E-02 8.23E-01 positive regulation of calcidiol 1-monooxygenase activity (GO:0060559) 3 1 .30 + 3.37 3.14E-01 1.00E00 detection of nodal flow (GO:0003127) 3 1 .30 + 3.37 3.14E-01 1.00E00 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development (GO:0060528) 3 1 .30 + 3.37 3.14E-01 1.00E00 spermine catabolic process (GO:0046208) 3 1 .30 + 3.37 3.14E-01 1.00E00 leukocyte cell-cell adhesion (GO:0007159) 51 17 5.04 + 3.37 8.03E-05 4.35E-03 cellular response to interferon-beta (GO:0035458) 39 13 3.86 + 3.37 5.42E-04 2.20E-02 positive regulation of B cell activation (GO:0050871) 139 46 13.74 + 3.35 1.25E-10 2.34E-08 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002460) 197 65 19.48 + 3.34 2.09E-14 6.89E-12 antimicrobial humoral response (GO:0019730) 64 21 6.33 + 3.32 1.48E-05 1.03E-03 leukocyte mediated immunity (GO:0002443) 214 70 21.16 + 3.31 2.93E-15 1.11E-12 regulation of phagocytosis (GO:0050764) 104 34 10.28 + 3.31 4.09E-08 5.60E-06 regulation of B cell activation (GO:0050864) 188 61 18.59 + 3.28 2.44E-13 6.98E-11 negative regulation of actin filament depolymerization (GO:0030835) 34 11 3.36 + 3.27 1.73E-03 5.53E-02 antigen processing and presentation of exogenous antigen (GO:0019884) 34 11 3.36 + 3.27 1.73E-03 5.52E-02 cell killing (GO:0001906) 65 21 6.43 + 3.27 1.79E-05 1.20E-03 myeloid cell development (GO:0061515) 65 21 6.43 + 3.27 1.79E-05 1.19E-03 regulation of myeloid leukocyte mediated immunity (GO:0002886) 65 21 6.43 + 3.27 1.79E-05 1.19E-03 positive regulation of macrophage activation (GO:0043032) 25 8 2.47 + 3.24 7.60E-03 1.75E-01 leukocyte chemotaxis (GO:0030595) 113 36 11.17 + 3.22 2.85E-08 4.11E-06 regulation of heterotypic cell-cell adhesion (GO:0034114) 22 7 2.18 + 3.22 1.26E-02 2.54E-01 mature B cell differentiation involved in immune response (GO:0002313) 22 7 2.18 + 3.22 1.26E-02 2.54E-01 temperature homeostasis (GO:0001659) 22 7 2.18 + 3.22 1.26E-02 2.53E-01 leukocyte adhesion to vascular endothelial cell (GO:0061756) 22 7 2.18 + 3.22 1.26E-02 2.53E-01 amyloid-beta clearance (GO:0097242) 22 7 2.18 + 3.22 1.26E-02 2.53E-01 activation of immune response (GO:0002253) 239 76 23.63 + 3.22 6.55E-16 2.92E-13 leukocyte mediated cytotoxicity (GO:0001909) 38 12 3.76 + 3.19 1.29E-03 4.44E-02 mucosal immune response (GO:0002385) 19 6 1.88 + 3.19 2.09E-02 3.55E-01 negative regulation of interleukin-12 production (GO:0032695) 19 6 1.88 + 3.19 2.09E-02 3.55E-01 actin filament-based transport (GO:0099515) 19 6 1.88 + 3.19 2.09E-02 3.54E-01 regulation of macrophage derived foam cell differentiation (GO:0010743) 19 6 1.88 + 3.19 2.09E-02 3.54E-01 regulation of interleukin-17 production (GO:0032660) 35 11 3.46 + 3.18 2.10E-03 6.46E-02 leukocyte migration (GO:0050900) 182 57 17.99 + 3.17 4.85E-12 1.10E-09 cellular copper ion homeostasis (GO:0006878) 16 5 1.58 + 3.16 3.52E-02 5.02E-01 regulation of MHC class II biosynthetic process (GO:0045346) 16 5 1.58 + 3.16 3.52E-02 5.02E-01 negative regulation of focal adhesion assembly (GO:0051895) 16 5 1.58 + 3.16 3.52E-02 5.01E-01 negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037) 16 5 1.58 + 3.16 3.52E-02 5.01E-01 catechol-containing compound biosynthetic process (GO:0009713) 16 5 1.58 + 3.16 3.52E-02 5.01E-01 regulation of macrophage cytokine production (GO:0010935) 16 5 1.58 + 3.16 3.52E-02 5.00E-01 negative regulation of cell-substrate junction organization (GO:0150118) 16 5 1.58 + 3.16 3.52E-02 5.00E-01 catecholamine biosynthetic process (GO:0042423) 16 5 1.58 + 3.16 3.52E-02 4.99E-01 macrophage activation (GO:0042116) 48 15 4.75 + 3.16 3.69E-04 1.58E-02 amino sugar catabolic process (GO:0046348) 16 5 1.58 + 3.16 3.52E-02 4.99E-01 negative regulation of production of molecular mediator of immune response (GO:0002701) 32 10 3.16 + 3.16 3.42E-03 9.48E-02 myeloid leukocyte mediated immunity (GO:0002444) 45 14 4.45 + 3.15 5.95E-04 2.39E-02 immune effector process (GO:0002252) 328 102 32.43 + 3.15 2.19E-20 1.66E-17 positive regulation of mononuclear cell migration (GO:0071677) 58 18 5.73 + 3.14 1.07E-04 5.50E-03 positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) 100 31 9.89 + 3.14 4.21E-07 4.80E-05 positive regulation of glycogen biosynthetic process (GO:0045725) 13 4 1.29 + 3.11 6.02E-02 6.89E-01 regulation of T-helper 2 cell differentiation (GO:0045628) 13 4 1.29 + 3.11 6.02E-02 6.88E-01 negative regulation of glial cell proliferation (GO:0060253) 13 4 1.29 + 3.11 6.02E-02 6.88E-01 unsaturated fatty acid biosynthetic process (GO:0006636) 26 8 2.57 + 3.11 9.17E-03 2.03E-01 positive regulation of interleukin-8 production (GO:0032757) 52 16 5.14 + 3.11 2.75E-04 1.25E-02 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043) 13 4 1.29 + 3.11 6.02E-02 6.87E-01 glycosaminoglycan catabolic process (GO:0006027) 13 4 1.29 + 3.11 6.02E-02 6.87E-01 positive regulation of neutrophil chemotaxis (GO:0090023) 26 8 2.57 + 3.11 9.17E-03 2.02E-01 CD8-positive, alpha-beta T cell activation (GO:0036037) 13 4 1.29 + 3.11 6.02E-02 6.86E-01 calcium-mediated signaling using intracellular calcium source (GO:0035584) 13 4 1.29 + 3.11 6.02E-02 6.86E-01 neuron remodeling (GO:0016322) 13 4 1.29 + 3.11 6.02E-02 6.85E-01 membrane repolarization (GO:0086009) 13 4 1.29 + 3.11 6.02E-02 6.85E-01 iron ion transmembrane transport (GO:0034755) 13 4 1.29 + 3.11 6.02E-02 6.84E-01 apoptotic process involved in morphogenesis (GO:0060561) 13 4 1.29 + 3.11 6.02E-02 6.84E-01 defense response to Gram-positive bacterium (GO:0050830) 75 23 7.42 + 3.10 1.46E-05 1.02E-03 positive regulation of tumor necrosis factor production (GO:0032760) 98 30 9.69 + 3.10 8.01E-07 8.21E-05 negative regulation of phagocytosis (GO:0050765) 23 7 2.27 + 3.08 1.51E-02 2.86E-01 positive regulation of leukocyte adhesion to vascular endothelial cell (GO:1904996) 23 7 2.27 + 3.08 1.51E-02 2.85E-01 animal organ regeneration (GO:0031100) 23 7 2.27 + 3.08 1.51E-02 2.85E-01 negative regulation of glucose transmembrane transport (GO:0010829) 23 7 2.27 + 3.08 1.51E-02 2.85E-01 signal transduction in absence of ligand (GO:0038034) 33 10 3.26 + 3.06 4.10E-03 1.08E-01 positive regulation of chemokine production (GO:0032722) 66 20 6.53 + 3.06 5.96E-05 3.41E-03 extrinsic apoptotic signaling pathway in absence of ligand (GO:0097192) 33 10 3.26 + 3.06 4.10E-03 1.08E-01 antigen processing and presentation of peptide antigen (GO:0048002) 53 16 5.24 + 3.05 3.29E-04 1.43E-02 positive regulation of interferon-gamma production (GO:0032729) 73 22 7.22 + 3.05 2.79E-05 1.78E-03 regulation of interferon-gamma production (GO:0032649) 103 31 10.18 + 3.04 7.15E-07 7.38E-05 positive regulation of antigen processing and presentation (GO:0002579) 10 3 .99 + 3.03 1.05E-01 9.00E-01 regulation of cell proliferation in bone marrow (GO:0071863) 10 3 .99 + 3.03 1.05E-01 9.00E-01 icosanoid transport (GO:0071715) 20 6 1.98 + 3.03 2.52E-02 4.01E-01 synapse maturation (GO:0060074) 10 3 .99 + 3.03 1.05E-01 8.99E-01 positive regulation of natural killer cell differentiation (GO:0032825) 10 3 .99 + 3.03 1.05E-01 8.99E-01 inflammatory response to wounding (GO:0090594) 10 3 .99 + 3.03 1.05E-01 8.98E-01 regulation of neutrophil extravasation (GO:2000389) 10 3 .99 + 3.03 1.05E-01 8.98E-01 regulation of interleukin-1 alpha production (GO:0032650) 10 3 .99 + 3.03 1.05E-01 8.97E-01 positive regulation of T-helper 17 type immune response (GO:2000318) 10 3 .99 + 3.03 1.05E-01 8.97E-01 cellular response to iron ion (GO:0071281) 10 3 .99 + 3.03 1.05E-01 8.96E-01 phagosome-lysosome fusion (GO:0090385) 10 3 .99 + 3.03 1.05E-01 8.96E-01 regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043619) 10 3 .99 + 3.03 1.05E-01 8.95E-01 excitatory synapse assembly (GO:1904861) 10 3 .99 + 3.03 1.05E-01 8.95E-01 hydrogen peroxide catabolic process (GO:0042744) 20 6 1.98 + 3.03 2.52E-02 4.01E-01 purine ribonucleoside monophosphate catabolic process (GO:0009169) 10 3 .99 + 3.03 1.05E-01 8.94E-01 T-helper 1 type immune response (GO:0042088) 20 6 1.98 + 3.03 2.52E-02 4.00E-01 reactive oxygen species biosynthetic process (GO:1903409) 10 3 .99 + 3.03 1.05E-01 8.94E-01 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process (GO:1902959) 10 3 .99 + 3.03 1.05E-01 8.93E-01 regulation of dendritic spine maintenance (GO:1902950) 10 3 .99 + 3.03 1.05E-01 8.93E-01 adaptive immune response (GO:0002250) 314 94 31.05 + 3.03 5.75E-18 3.49E-15 response to bacterium (GO:0009617) 526 157 52.01 + 3.02 2.12E-29 3.57E-26 lymphocyte migration (GO:0072676) 47 14 4.65 + 3.01 8.50E-04 3.17E-02 response to interferon-gamma (GO:0034341) 101 30 9.99 + 3.00 1.35E-06 1.27E-04 prostaglandin metabolic process (GO:0006693) 27 8 2.67 + 3.00 1.10E-02 2.35E-01 prostanoid metabolic process (GO:0006692) 27 8 2.67 + 3.00 1.10E-02 2.35E-01 negative regulation of interleukin-1 production (GO:0032692) 27 8 2.67 + 3.00 1.10E-02 2.35E-01 lymphocyte chemotaxis (GO:0048247) 27 8 2.67 + 3.00 1.10E-02 2.34E-01 B cell proliferation (GO:0042100) 27 8 2.67 + 3.00 1.10E-02 2.34E-01 mononuclear cell migration (GO:0071674) 71 21 7.02 + 2.99 5.28E-05 3.09E-03 regulation of acute inflammatory response (GO:0002673) 44 13 4.35 + 2.99 1.37E-03 4.65E-02 positive regulation of neutrophil migration (GO:1902624) 34 10 3.36 + 2.97 4.89E-03 1.23E-01 negative regulation of amyloid-beta formation (GO:1902430) 17 5 1.68 + 2.97 4.23E-02 5.58E-01 regulation of glutamate secretion (GO:0014048) 17 5 1.68 + 2.97 4.23E-02 5.58E-01 positive regulation of reactive oxygen species metabolic process (GO:2000379) 68 20 6.72 + 2.97 8.42E-05 4.50E-03 white fat cell differentiation (GO:0050872) 17 5 1.68 + 2.97 4.23E-02 5.57E-01 positive regulation of myelination (GO:0031643) 17 5 1.68 + 2.97 4.23E-02 5.57E-01 response to hepatocyte growth factor (GO:0035728) 17 5 1.68 + 2.97 4.23E-02 5.56E-01 regulation of B cell proliferation (GO:0030888) 68 20 6.72 + 2.97 8.42E-05 4.48E-03 amino acid import (GO:0043090) 34 10 3.36 + 2.97 4.89E-03 1.23E-01 regulation of macrophage activation (GO:0043030) 51 15 5.04 + 2.97 6.28E-04 2.51E-02 positive regulation of hemostasis (GO:1900048) 17 5 1.68 + 2.97 4.23E-02 5.56E-01 negative regulation of cytokine production involved in inflammatory response (GO:1900016) 17 5 1.68 + 2.97 4.23E-02 5.55E-01 positive regulation of blood coagulation (GO:0030194) 17 5 1.68 + 2.97 4.23E-02 5.55E-01 positive regulation of inflammatory response to antigenic stimulus (GO:0002863) 17 5 1.68 + 2.97 4.23E-02 5.55E-01 positive regulation of reactive oxygen species biosynthetic process (GO:1903428) 17 5 1.68 + 2.97 4.23E-02 5.54E-01 positive regulation of leukocyte chemotaxis (GO:0002690) 85 25 8.40 + 2.97 1.15E-05 8.41E-04 cell recognition (GO:0008037) 157 46 15.52 + 2.96 3.23E-09 5.28E-07 apoptotic cell clearance (GO:0043277) 41 12 4.05 + 2.96 2.21E-03 6.71E-02 phenol-containing compound biosynthetic process (GO:0046189) 24 7 2.37 + 2.95 1.81E-02 3.24E-01 collagen catabolic process (GO:0030574) 24 7 2.37 + 2.95 1.81E-02 3.24E-01 negative regulation of anion transport (GO:1903792) 24 7 2.37 + 2.95 1.81E-02 3.23E-01 negative regulation of interferon-gamma production (GO:0032689) 31 9 3.07 + 2.94 7.96E-03 1.83E-01 regulation of T cell cytokine production (GO:0002724) 31 9 3.07 + 2.94 7.96E-03 1.82E-01 inflammatory response (GO:0006954) 376 109 37.18 + 2.93 9.17E-20 6.05E-17 regulation of tumor necrosis factor superfamily cytokine production (GO:1903555) 163 47 16.12 + 2.92 5.55E-09 8.78E-07 negative regulation of inflammatory response (GO:0050728) 118 34 11.67 + 2.91 4.91E-07 5.40E-05 regulation of tumor necrosis factor production (GO:0032680) 160 46 15.82 + 2.91 8.53E-09 1.32E-06 icosanoid metabolic process (GO:0006690) 63 18 6.23 + 2.89 2.53E-04 1.18E-02 positive regulation of interleukin-6 production (GO:0032755) 91 26 9.00 + 2.89 1.19E-05 8.66E-04 negative regulation of B cell activation (GO:0050869) 35 10 3.46 + 2.89 5.79E-03 1.41E-01 negative regulation of purine nucleotide metabolic process (GO:1900543) 21 6 2.08 + 2.89 3.00E-02 4.50E-01 negative regulation of nucleotide metabolic process (GO:0045980) 21 6 2.08 + 2.89 3.00E-02 4.49E-01 positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:0061081) 21 6 2.08 + 2.89 3.00E-02 4.49E-01 positive regulation of cellular extravasation (GO:0002693) 21 6 2.08 + 2.89 3.00E-02 4.48E-01 regulation of T cell anergy (GO:0002667) 7 2 .69 + 2.89 1.91E-01 1.00E00 negative regulation of action potential (GO:0045759) 7 2 .69 + 2.89 1.91E-01 1.00E00 allantoin biosynthetic process (GO:0019428) 7 2 .69 + 2.89 1.91E-01 1.00E00 cerebellar granule cell differentiation (GO:0021707) 7 2 .69 + 2.89 1.91E-01 1.00E00 bud elongation involved in lung branching (GO:0060449) 7 2 .69 + 2.89 1.91E-01 1.00E00 branching involved in salivary gland morphogenesis (GO:0060445) 14 4 1.38 + 2.89 7.21E-02 7.42E-01 lung vasculature development (GO:0060426) 7 2 .69 + 2.89 1.91E-01 1.00E00 complement activation, alternative pathway (GO:0006957) 7 2 .69 + 2.89 1.91E-01 1.00E00 positive regulation of tissue remodeling (GO:0034105) 7 2 .69 + 2.89 1.91E-01 1.00E00 regulation of melanocyte differentiation (GO:0045634) 7 2 .69 + 2.89 1.91E-01 1.00E00 positive regulation of T-helper 2 cell differentiation (GO:0045630) 7 2 .69 + 2.89 1.91E-01 1.00E00 cerebellar granular layer formation (GO:0021684) 7 2 .69 + 2.89 1.91E-01 1.00E00 dGMP metabolic process (GO:0046054) 7 2 .69 + 2.89 1.91E-01 1.00E00 SMAD protein complex assembly (GO:0007183) 7 2 .69 + 2.89 1.91E-01 1.00E00 serotonin secretion (GO:0001820) 7 2 .69 + 2.89 1.91E-01 1.00E00 positive regulation of glomerular mesangial cell proliferation (GO:0072126) 7 2 .69 + 2.89 1.91E-01 1.00E00 regulation of dopamine receptor signaling pathway (GO:0060159) 7 2 .69 + 2.89 1.91E-01 1.00E00 negative regulation of collagen biosynthetic process (GO:0032966) 14 4 1.38 + 2.89 7.21E-02 7.42E-01 positive regulation of growth hormone secretion (GO:0060124) 7 2 .69 + 2.89 1.91E-01 1.00E00 positive regulation of granulocyte chemotaxis (GO:0071624) 28 8 2.77 + 2.89 1.30E-02 2.57E-01 virion attachment to host cell (GO:0019062) 7 2 .69 + 2.89 1.91E-01 1.00E00 regulation of platelet-derived growth factor receptor-beta signaling pathway (GO:2000586) 7 2 .69 + 2.89 1.91E-01 1.00E00 late nucleophagy (GO:0044805) 7 2 .69 + 2.89 1.91E-01 1.00E00 regulation of natural killer cell proliferation (GO:0032817) 7 2 .69 + 2.89 1.91E-01 1.00E00 regulation of relaxation of cardiac muscle (GO:1901897) 7 2 .69 + 2.89 1.91E-01 1.00E00 negative regulation of cellular amine metabolic process (GO:0033239) 7 2 .69 + 2.89 1.91E-01 1.00E00 positive regulation of interleukin-1 alpha production (GO:0032730) 7 2 .69 + 2.89 1.91E-01 1.00E00 cellular hyperosmotic response (GO:0071474) 7 2 .69 + 2.89 1.91E-01 1.00E00 adhesion of symbiont to host cell (GO:0044650) 7 2 .69 + 2.89 1.91E-01 1.00E00 cellular response to gonadotropin stimulus (GO:0071371) 7 2 .69 + 2.89 1.91E-01 1.00E00 regulatory T cell differentiation (GO:0045066) 7 2 .69 + 2.89 1.91E-01 1.00E00 regulation of male germ cell proliferation (GO:2000254) 7 2 .69 + 2.89 1.91E-01 1.00E00 regulation of germ cell proliferation (GO:1905936) 7 2 .69 + 2.89 1.91E-01 1.00E00 response to bacterial lipoprotein (GO:0032493) 7 2 .69 + 2.89 1.91E-01 1.00E00 Cdc42 protein signal transduction (GO:0032488) 7 2 .69 + 2.89 1.91E-01 1.00E00 purine nucleoside catabolic process (GO:0006152) 7 2 .69 + 2.89 1.91E-01 1.00E00 positive regulation of cell-cell adhesion mediated by cadherin (GO:2000049) 7 2 .69 + 2.89 1.91E-01 1.00E00 regulation of flagellated sperm motility (GO:1901317) 7 2 .69 + 2.89 1.91E-01 1.00E00 regulation of blood-brain barrier permeability (GO:1905603) 7 2 .69 + 2.89 1.91E-01 1.00E00 leukocyte aggregation (GO:0070486) 14 4 1.38 + 2.89 7.21E-02 7.41E-01 positive regulation of B cell receptor signaling pathway (GO:0050861) 7 2 .69 + 2.89 1.91E-01 1.00E00 TRAIL-activated apoptotic signaling pathway (GO:0036462) 7 2 .69 + 2.89 1.91E-01 1.00E00 positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568) 7 2 .69 + 2.89 1.91E-01 1.00E00 positive regulation of vascular associated smooth muscle cell apoptotic process (GO:1905461) 7 2 .69 + 2.89 1.91E-01 1.00E00 positive regulation of autophagosome maturation (GO:1901098) 7 2 .69 + 2.89 1.91E-01 1.00E00 regulation of leukocyte adhesion to vascular endothelial cell (GO:1904994) 28 8 2.77 + 2.89 1.30E-02 2.56E-01 protein trimerization (GO:0070206) 14 4 1.38 + 2.89 7.21E-02 7.41E-01 learned vocalization behavior or vocal learning (GO:0098598) 7 2 .69 + 2.89 1.91E-01 1.00E00 negative regulation of urine volume (GO:0035811) 7 2 .69 + 2.89 1.91E-01 1.00E00 lipoprotein transport (GO:0042953) 14 4 1.38 + 2.89 7.21E-02 7.40E-01 regulation of leukocyte degranulation (GO:0043300) 49 14 4.84 + 2.89 1.19E-03 4.19E-02 bone mineralization involved in bone maturation (GO:0035630) 7 2 .69 + 2.89 1.91E-01 1.00E00 nucleotide salvage (GO:0043173) 7 2 .69 + 2.89 1.91E-01 1.00E00 positive regulation of receptor binding (GO:1900122) 7 2 .69 + 2.89 1.91E-01 1.00E00 purine deoxyribonucleoside monophosphate catabolic process (GO:0009172) 7 2 .69 + 2.89 1.91E-01 1.00E00 L-alanine transport (GO:0015808) 7 2 .69 + 2.89 1.91E-01 1.00E00 exocrine pancreas development (GO:0031017) 7 2 .69 + 2.89 1.91E-01 1.00E00 positive regulation of microglial cell activation (GO:1903980) 7 2 .69 + 2.89 1.91E-01 1.00E00 membrane repolarization during action potential (GO:0086011) 7 2 .69 + 2.89 1.91E-01 1.00E00 positive regulation of cardiac epithelial to mesenchymal transition (GO:0062043) 7 2 .69 + 2.89 1.91E-01 1.00E00 melanin biosynthetic process (GO:0042438) 7 2 .69 + 2.89 1.91E-01 1.00E00 negative regulation of cholesterol storage (GO:0010887) 7 2 .69 + 2.89 1.91E-01 1.00E00 positive regulation of cholesterol esterification (GO:0010873) 7 2 .69 + 2.89 1.91E-01 1.00E00 microglial cell proliferation (GO:0061518) 7 2 .69 + 2.89 1.91E-01 1.00E00 macrophage proliferation (GO:0061517) 7 2 .69 + 2.89 1.91E-01 1.00E00 gas transport (GO:0015669) 7 2 .69 + 2.89 1.91E-01 1.00E00 negative regulation of sodium ion transport (GO:0010766) 14 4 1.38 + 2.89 7.21E-02 7.40E-01 regulation of long-chain fatty acid import across plasma membrane (GO:0010746) 7 2 .69 + 2.89 1.91E-01 1.00E00 negative regulation of collagen metabolic process (GO:0010713) 14 4 1.38 + 2.89 7.21E-02 7.39E-01 regulation of I-kappaB phosphorylation (GO:1903719) 7 2 .69 + 2.89 1.91E-01 1.00E00 hyaluronan catabolic process (GO:0030214) 7 2 .69 + 2.89 1.91E-01 1.00E00 hyaluronan metabolic process (GO:0030212) 14 4 1.38 + 2.89 7.21E-02 7.39E-01 positive regulation of sensory perception of pain (GO:1904058) 7 2 .69 + 2.89 1.91E-01 1.00E00 opsonization (GO:0008228) 7 2 .69 + 2.89 1.91E-01 1.00E00 regulation of lymphocyte anergy (GO:0002911) 7 2 .69 + 2.89 1.91E-01 1.00E00 spermine metabolic process (GO:0008215) 7 2 .69 + 2.89 1.91E-01 1.00E00 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis (GO:1903589) 7 2 .69 + 2.89 1.91E-01 1.00E00 postsynaptic density assembly (GO:0097107) 7 2 .69 + 2.89 1.91E-01 1.00E00 T cell extravasation (GO:0072683) 7 2 .69 + 2.89 1.91E-01 1.00E00 lymphocyte migration into lymphoid organs (GO:0097021) 7 2 .69 + 2.89 1.91E-01 1.00E00 pH elevation (GO:0045852) 7 2 .69 + 2.89 1.91E-01 1.00E00 visceral serous pericardium development (GO:0061032) 7 2 .69 + 2.89 1.91E-01 1.00E00 parturition (GO:0007567) 7 2 .69 + 2.89 1.91E-01 1.00E00 regulation of calcidiol 1-monooxygenase activity (GO:0060558) 7 2 .69 + 2.89 1.91E-01 1.00E00 regulation of leukocyte chemotaxis (GO:0002688) 109 31 10.78 + 2.88 1.95E-06 1.77E-04 negative regulation of leukocyte activation (GO:0002695) 176 50 17.40 + 2.87 2.09E-09 3.65E-07 production of molecular mediator of immune response (GO:0002440) 120 34 11.86 + 2.87 6.78E-07 7.05E-05 positive regulation of glial cell differentiation (GO:0045687) 39 11 3.86 + 2.85 4.21E-03 1.09E-01 mononuclear cell proliferation (GO:0032943) 78 22 7.71 + 2.85 6.42E-05 3.65E-03 regulation of sensory perception of pain (GO:0051930) 39 11 3.86 + 2.85 4.21E-03 1.09E-01 neutral amino acid transport (GO:0015804) 32 9 3.16 + 2.84 9.40E-03 2.06E-01 T cell activation involved in immune response (GO:0002286) 57 16 5.64 + 2.84 6.43E-04 2.56E-02 positive regulation of natural killer cell activation (GO:0032816) 25 7 2.47 + 2.83 2.14E-02 3.60E-01 positive regulation of p38MAPK cascade (GO:1900745) 25 7 2.47 + 2.83 2.14E-02 3.60E-01 positive regulation of phosphatidylinositol 3-kinase activity (GO:0043552) 25 7 2.47 + 2.83 2.14E-02 3.59E-01 response to lipoprotein particle (GO:0055094) 25 7 2.47 + 2.83 2.14E-02 3.59E-01 regulation of nitric oxide biosynthetic process (GO:0045428) 61 17 6.03 + 2.82 4.73E-04 1.95E-02 response to iron ion (GO:0010039) 18 5 1.78 + 2.81 5.02E-02 6.07E-01 alpha-beta T cell lineage commitment (GO:0002363) 18 5 1.78 + 2.81 5.02E-02 6.07E-01 granulocyte differentiation (GO:0030851) 18 5 1.78 + 2.81 5.02E-02 6.06E-01 transport across blood-brain barrier (GO:0150104) 18 5 1.78 + 2.81 5.02E-02 6.06E-01 regulation of complement activation (GO:0030449) 18 5 1.78 + 2.81 5.02E-02 6.05E-01 positive regulation of leukocyte activation (GO:0002696) 368 102 36.38 + 2.80 1.98E-17 1.07E-14 CD4-positive, alpha-beta T cell activation (GO:0035710) 47 13 4.65 + 2.80 2.24E-03 6.79E-02 positive regulation of toll-like receptor signaling pathway (GO:0034123) 29 8 2.87 + 2.79 1.53E-02 2.87E-01 mature B cell differentiation (GO:0002335) 29 8 2.87 + 2.79 1.53E-02 2.86E-01 regulation of myeloid cell apoptotic process (GO:0033032) 29 8 2.87 + 2.79 1.53E-02 2.86E-01 positive regulation of leukocyte degranulation (GO:0043302) 29 8 2.87 + 2.79 1.53E-02 2.86E-01 regulation of sensory perception (GO:0051931) 40 11 3.95 + 2.78 4.94E-03 1.24E-01 lymphocyte activation involved in immune response (GO:0002285) 102 28 10.08 + 2.78 1.50E-05 1.04E-03 negative regulation of cell activation (GO:0050866) 194 53 19.18 + 2.76 1.74E-09 3.06E-07 regulation of neutrophil chemotaxis (GO:0090022) 33 9 3.26 + 2.76 1.10E-02 2.34E-01 positive regulation of lymphocyte activation (GO:0051251) 319 87 31.54 + 2.76 1.08E-14 3.63E-12 regulation of toll-like receptor 4 signaling pathway (GO:0034143) 22 6 2.18 + 2.76 3.54E-02 4.99E-01 positive regulation of heterotypic cell-cell adhesion (GO:0034116) 11 3 1.09 + 2.76 1.25E-01 1.00E00 lateral ventricle development (GO:0021670) 11 3 1.09 + 2.76 1.25E-01 1.00E00 positive regulation of vasculogenesis (GO:2001214) 11 3 1.09 + 2.76 1.25E-01 9.99E-01 negative regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902548) 11 3 1.09 + 2.76 1.25E-01 9.98E-01 organ or tissue specific immune response (GO:0002251) 22 6 2.18 + 2.76 3.54E-02 4.99E-01 regulation of high voltage-gated calcium channel activity (GO:1901841) 11 3 1.09 + 2.76 1.25E-01 9.98E-01 semaphorin-plexin signaling pathway involved in axon guidance (GO:1902287) 11 3 1.09 + 2.76 1.25E-01 9.97E-01 regulation of chemokine production (GO:0032642) 88 24 8.70 + 2.76 7.28E-05 4.05E-03 actin crosslink formation (GO:0051764) 11 3 1.09 + 2.76 1.25E-01 9.97E-01 T-helper 1 cell differentiation (GO:0045063) 11 3 1.09 + 2.76 1.25E-01 9.96E-01 regulation of immature T cell proliferation (GO:0033083) 11 3 1.09 + 2.76 1.25E-01 9.96E-01 negative regulation of platelet aggregation (GO:0090331) 11 3 1.09 + 2.76 1.25E-01 9.95E-01 leukocyte proliferation (GO:0070661) 88 24 8.70 + 2.76 7.28E-05 4.03E-03 cellular response to oxidised low-density lipoprotein particle stimulus (GO:0140052) 11 3 1.09 + 2.76 1.25E-01 9.95E-01 mitophagy (GO:0000423) 11 3 1.09 + 2.76 1.25E-01 9.94E-01 regulation of vascular associated smooth muscle cell apoptotic process (GO:1905459) 11 3 1.09 + 2.76 1.25E-01 9.94E-01 detection of external biotic stimulus (GO:0098581) 22 6 2.18 + 2.76 3.54E-02 4.98E-01 negative regulation of biomineral tissue development (GO:0070168) 22 6 2.18 + 2.76 3.54E-02 4.98E-01 regulation of aspartic-type peptidase activity (GO:1905245) 11 3 1.09 + 2.76 1.25E-01 9.93E-01 positive regulation of B cell proliferation (GO:0030890) 44 12 4.35 + 2.76 3.60E-03 9.88E-02 ceramide transport (GO:0035627) 11 3 1.09 + 2.76 1.25E-01 9.93E-01 positive regulation of synaptic vesicle endocytosis (GO:1900244) 11 3 1.09 + 2.76 1.25E-01 9.92E-01 zinc ion homeostasis (GO:0055069) 22 6 2.18 + 2.76 3.54E-02 4.97E-01 purine nucleoside monophosphate catabolic process (GO:0009128) 11 3 1.09 + 2.76 1.25E-01 9.92E-01 positive regulation of glial cell migration (GO:1903977) 11 3 1.09 + 2.76 1.25E-01 9.91E-01 negative regulation of anion transmembrane transport (GO:1903960) 11 3 1.09 + 2.76 1.25E-01 9.91E-01 ionotropic glutamate receptor signaling pathway (GO:0035235) 11 3 1.09 + 2.76 1.25E-01 9.90E-01 regulation of type B pancreatic cell proliferation (GO:0061469) 11 3 1.09 + 2.76 1.25E-01 9.90E-01 lymphocyte proliferation (GO:0046651) 77 21 7.61 + 2.76 1.39E-04 6.80E-03 epithelial cell differentiation involved in prostate gland development (GO:0060742) 11 3 1.09 + 2.76 1.25E-01 9.89E-01 positive regulation of inositol phosphate biosynthetic process (GO:0060732) 11 3 1.09 + 2.76 1.25E-01 9.89E-01 labyrinthine layer morphogenesis (GO:0060713) 22 6 2.18 + 2.76 3.54E-02 4.97E-01 regulation of secondary heart field cardioblast proliferation (GO:0003266) 11 3 1.09 + 2.76 1.25E-01 9.88E-01 regulation of anion channel activity (GO:0010359) 11 3 1.09 + 2.76 1.25E-01 9.88E-01 positive regulation of T cell cytokine production (GO:0002726) 22 6 2.18 + 2.76 3.54E-02 4.96E-01 negative regulation of cytokine production involved in immune response (GO:0002719) 22 6 2.18 + 2.76 3.54E-02 4.96E-01 erythrocyte homeostasis (GO:0034101) 103 28 10.18 + 2.75 1.63E-05 1.12E-03 regulation of cellular extravasation (GO:0002691) 37 10 3.66 + 2.73 7.97E-03 1.82E-01 regulation of nitric oxide metabolic process (GO:0080164) 63 17 6.23 + 2.73 6.44E-04 2.56E-02 epithelial cell apoptotic process (GO:1904019) 26 7 2.57 + 2.72 2.51E-02 4.00E-01 negative regulation of lymphocyte activation (GO:0051250) 145 39 14.34 + 2.72 3.52E-07 4.05E-05 erythrocyte differentiation (GO:0030218) 93 25 9.20 + 2.72 5.51E-05 3.19E-03 myeloid leukocyte activation (GO:0002274) 123 33 12.16 + 2.71 3.07E-06 2.65E-04 actin filament bundle organization (GO:0061572) 56 15 5.54 + 2.71 1.40E-03 4.71E-02 regulation of leukocyte activation (GO:0002694) 564 151 55.76 + 2.71 4.72E-24 4.78E-21 innate immune response (GO:0045087) 551 147 54.48 + 2.70 2.57E-23 2.44E-20 regulation of monocyte differentiation (GO:0045655) 15 4 1.48 + 2.70 8.51E-02 8.40E-01 phagolysosome assembly (GO:0001845) 15 4 1.48 + 2.70 8.51E-02 8.39E-01 lipoprotein localization (GO:0044872) 15 4 1.48 + 2.70 8.51E-02 8.39E-01 regulation of natural killer cell differentiation (GO:0032823) 15 4 1.48 + 2.70 8.51E-02 8.38E-01 adaptive thermogenesis (GO:1990845) 15 4 1.48 + 2.70 8.51E-02 8.38E-01 positive regulation of glycogen metabolic process (GO:0070875) 15 4 1.48 + 2.70 8.51E-02 8.37E-01 positive regulation of actin cytoskeleton reorganization (GO:2000251) 15 4 1.48 + 2.70 8.51E-02 8.37E-01 response to leptin (GO:0044321) 15 4 1.48 + 2.70 8.51E-02 8.36E-01 regulation of inclusion body assembly (GO:0090083) 15 4 1.48 + 2.70 8.51E-02 8.36E-01 modulation by symbiont of host cellular process (GO:0044068) 15 4 1.48 + 2.70 8.51E-02 8.35E-01 positive regulation of membrane protein ectodomain proteolysis (GO:0051044) 15 4 1.48 + 2.70 8.51E-02 8.35E-01 inactivation of MAPK activity (GO:0000188) 15 4 1.48 + 2.70 8.51E-02 8.34E-01 cardiac myofibril assembly (GO:0055003) 15 4 1.48 + 2.70 8.51E-02 8.34E-01 negative regulation of macrophage activation (GO:0043031) 15 4 1.48 + 2.70 8.51E-02 8.33E-01 bile acid and bile salt transport (GO:0015721) 15 4 1.48 + 2.70 8.51E-02 8.32E-01 regulation of inflammatory response to antigenic stimulus (GO:0002861) 30 8 2.97 + 2.70 1.79E-02 3.25E-01 positive regulation of fatty acid oxidation (GO:0046321) 15 4 1.48 + 2.70 8.51E-02 8.32E-01 negative regulation of glycolytic process (GO:0045820) 15 4 1.48 + 2.70 8.51E-02 8.31E-01 positive regulation of cell activation (GO:0050867) 383 102 37.87 + 2.69 1.86E-16 8.82E-14 regulation of actin cytoskeleton reorganization (GO:2000249) 34 9 3.36 + 2.68 1.29E-02 2.55E-01 dendritic cell differentiation (GO:0097028) 34 9 3.36 + 2.68 1.29E-02 2.55E-01 positive regulation of inflammatory response (GO:0050729) 121 32 11.96 + 2.67 5.39E-06 4.47E-04 antigen processing and presentation (GO:0019882) 87 23 8.60 + 2.67 1.32E-04 6.47E-03 regulation of interleukin-10 production (GO:0032653) 53 14 5.24 + 2.67 2.22E-03 6.74E-02 vascular transport (GO:0010232) 19 5 1.88 + 2.66 5.89E-02 6.82E-01 cellular sodium ion homeostasis (GO:0006883) 19 5 1.88 + 2.66 5.89E-02 6.82E-01 leukocyte tethering or rolling (GO:0050901) 19 5 1.88 + 2.66 5.89E-02 6.81E-01 regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664) 19 5 1.88 + 2.66 5.89E-02 6.81E-01 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) 19 5 1.88 + 2.66 5.89E-02 6.80E-01 chemokine-mediated signaling pathway (GO:0070098) 38 10 3.76 + 2.66 9.27E-03 2.05E-01 negative regulation of B cell proliferation (GO:0030889) 19 5 1.88 + 2.66 5.89E-02 6.80E-01 regulation of glial cell migration (GO:1903975) 19 5 1.88 + 2.66 5.89E-02 6.79E-01 plasma lipoprotein particle clearance (GO:0034381) 19 5 1.88 + 2.66 5.89E-02 6.79E-01 regulation of interleukin-6 production (GO:0032675) 141 37 13.94 + 2.65 1.12E-06 1.09E-04 CD4-positive, alpha-beta T cell differentiation (GO:0043367) 42 11 4.15 + 2.65 6.70E-03 1.60E-01 myeloid cell homeostasis (GO:0002262) 130 34 12.85 + 2.65 3.25E-06 2.78E-04 positive regulation of leukocyte migration (GO:0002687) 134 35 13.25 + 2.64 2.38E-06 2.08E-04 negative regulation of biomineralization (GO:0110150) 23 6 2.27 + 2.64 4.13E-02 5.49E-01 regulation of neutrophil migration (GO:1902622) 46 12 4.55 + 2.64 4.86E-03 1.23E-01 regulation of interleukin-1 production (GO:0032652) 92 24 9.10 + 2.64 1.03E-04 5.35E-03 negative regulation of viral genome replication (GO:0045071) 46 12 4.55 + 2.64 4.86E-03 1.23E-01 negative regulation of viral entry into host cell (GO:0046597) 23 6 2.27 + 2.64 4.13E-02 5.49E-01 aortic valve development (GO:0003176) 23 6 2.27 + 2.64 4.13E-02 5.48E-01 regulation of lymphocyte activation (GO:0051249) 470 122 46.47 + 2.63 1.02E-18 6.44E-16 positive regulation of erythrocyte differentiation (GO:0045648) 27 7 2.67 + 2.62 2.92E-02 4.41E-01 cellular response to lipoprotein particle stimulus (GO:0071402) 27 7 2.67 + 2.62 2.92E-02 4.41E-01 regulation of interleukin-12 production (GO:0032655) 54 14 5.34 + 2.62 4.19E-03 1.09E-01 regulation of fibroblast growth factor receptor signaling pathway (GO:0040036) 27 7 2.67 + 2.62 2.92E-02 4.41E-01 response to fatty acid (GO:0070542) 27 7 2.67 + 2.62 2.92E-02 4.40E-01 actin filament bundle assembly (GO:0051017) 54 14 5.34 + 2.62 4.19E-03 1.09E-01 negative regulation of cell-matrix adhesion (GO:0001953) 31 8 3.07 + 2.61 2.08E-02 3.56E-01 metal ion export (GO:0070839) 31 8 3.07 + 2.61 2.08E-02 3.55E-01 regulation of astrocyte differentiation (GO:0048710) 31 8 3.07 + 2.61 2.08E-02 3.55E-01 cellular response to metal ion (GO:0071248) 128 33 12.66 + 2.61 5.76E-06 4.72E-04 regulation of inflammatory response (GO:0050727) 295 76 29.17 + 2.61 5.85E-12 1.29E-09 cell chemotaxis (GO:0060326) 167 43 16.51 + 2.60 2.78E-07 3.27E-05 regulation of cell activation (GO:0050865) 602 155 59.52 + 2.60 2.81E-23 2.51E-20 defense response (GO:0006952) 1001 257 98.97 + 2.60 6.36E-39 3.22E-35 T cell mediated immunity (GO:0002456) 39 10 3.86 + 2.59 1.07E-02 2.31E-01 regulation of natural killer cell activation (GO:0032814) 39 10 3.86 + 2.59 1.07E-02 2.31E-01 defense response to other organism (GO:0098542) 718 184 70.99 + 2.59 1.70E-27 2.34E-24 positive regulation of lymphocyte proliferation (GO:0050671) 129 33 12.75 + 2.59 1.00E-05 7.65E-04 positive regulation of myeloid leukocyte differentiation (GO:0002763) 63 16 6.23 + 2.57 2.15E-03 6.55E-02 positive regulation of immune response (GO:0050778) 469 119 46.37 + 2.57 1.29E-17 7.27E-15 regulation of interleukin-1 beta production (GO:0032651) 75 19 7.42 + 2.56 7.54E-04 2.90E-02 biological process involved in interaction with symbiont (GO:0051702) 75 19 7.42 + 2.56 7.54E-04 2.90E-02 transition metal ion homeostasis (GO:0055076) 107 27 10.58 + 2.55 5.53E-05 3.19E-03 positive regulation of mononuclear cell proliferation (GO:0032946) 131 33 12.95 + 2.55 1.14E-05 8.42E-04 heat acclimation (GO:0010286) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of gluconeogenesis (GO:0045721) 16 4 1.58 + 2.53 9.91E-02 8.69E-01 striatal medium spiny neuron differentiation (GO:0021773) 4 1 .40 + 2.53 3.76E-01 1.00E00 cochlear nucleus development (GO:0021747) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of endodermal cell differentiation (GO:1903224) 4 1 .40 + 2.53 3.76E-01 1.00E00 glomerular filtration (GO:0003094) 12 3 1.19 + 2.53 1.47E-01 1.00E00 negative regulation of forebrain neuron differentiation (GO:2000978) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of pro-B cell differentiation (GO:2000973) 8 2 .79 + 2.53 2.25E-01 1.00E00 bronchiole development (GO:0060435) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of sterol import (GO:2000911) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of chondrocyte proliferation (GO:1902732) 8 2 .79 + 2.53 2.25E-01 1.00E00 hypoxanthine metabolic process (GO:0046100) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of antigen processing and presentation of peptide antigen via MHC class II (GO:0002586) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of antigen processing and presentation of peptide antigen (GO:0002584) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of MyD88-dependent toll-like receptor signaling pathway (GO:0034124) 4 1 .40 + 2.53 3.76E-01 1.00E00 substrate-dependent cell migration, cell extension (GO:0006930) 8 2 .79 + 2.53 2.25E-01 1.00E00 platelet degranulation (GO:0002576) 8 2 .79 + 2.53 2.25E-01 1.00E00 mast cell chemotaxis (GO:0002551) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of myoblast differentiation (GO:0045662) 24 6 2.37 + 2.53 4.78E-02 5.92E-01 regulation of neutrophil differentiation (GO:0045658) 4 1 .40 + 2.53 3.76E-01 1.00E00 osteoblast proliferation (GO:0033687) 4 1 .40 + 2.53 3.76E-01 1.00E00 cerebellar granular layer development (GO:0021681) 12 3 1.19 + 2.53 1.47E-01 1.00E00 lipoxin biosynthetic process (GO:2001301) 4 1 .40 + 2.53 3.76E-01 1.00E00 lipoxin metabolic process (GO:2001300) 4 1 .40 + 2.53 3.76E-01 1.00E00 compartment pattern specification (GO:0007386) 4 1 .40 + 2.53 3.76E-01 1.00E00 membrane protein proteolysis (GO:0033619) 32 8 3.16 + 2.53 2.41E-02 3.91E-01 negative regulation of catecholamine secretion (GO:0033604) 12 3 1.19 + 2.53 1.47E-01 1.00E00 trigeminal nerve structural organization (GO:0021637) 4 1 .40 + 2.53 3.76E-01 1.00E00 trigeminal nerve morphogenesis (GO:0021636) 4 1 .40 + 2.53 3.76E-01 1.00E00 blastoderm segmentation (GO:0007350) 12 3 1.19 + 2.53 1.47E-01 1.00E00 regulation of mitochondrial transcription (GO:1903108) 4 1 .40 + 2.53 3.76E-01 1.00E00 rescue of stalled ribosome (GO:0072344) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of aldosterone secretion (GO:2000858) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of mineralocorticoid secretion (GO:2000855) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of corticosteroid hormone secretion (GO:2000848) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of receptor localization to synapse (GO:1902685) 4 1 .40 + 2.53 3.76E-01 1.00E00 maintenance of mitotic sister chromatid cohesion (GO:0034088) 4 1 .40 + 2.53 3.76E-01 1.00E00 maintenance of sister chromatid cohesion (GO:0034086) 4 1 .40 + 2.53 3.76E-01 1.00E00 cellular zinc ion homeostasis (GO:0006882) 20 5 1.98 + 2.53 6.84E-02 7.28E-01 odontoblast differentiation (GO:0071895) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of circadian sleep/wake cycle, non-REM sleep (GO:0046010) 4 1 .40 + 2.53 3.76E-01 1.00E00 oligopeptide transport (GO:0006857) 12 3 1.19 + 2.53 1.47E-01 1.00E00 negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway (GO:0071878) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of cell proliferation in bone marrow (GO:0071864) 8 2 .79 + 2.53 2.25E-01 1.00E00 copper ion transport (GO:0006825) 12 3 1.19 + 2.53 1.47E-01 1.00E00 triglyceride-rich lipoprotein particle clearance (GO:0071830) 4 1 .40 + 2.53 3.76E-01 1.00E00 serotonin secretion involved in inflammatory response (GO:0002442) 4 1 .40 + 2.53 3.76E-01 1.00E00 response to iron(II) ion (GO:0010040) 4 1 .40 + 2.53 3.76E-01 1.00E00 basophil activation (GO:0045575) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (GO:2001267) 16 4 1.58 + 2.53 9.91E-02 8.68E-01 dendritic cell chemotaxis (GO:0002407) 8 2 .79 + 2.53 2.25E-01 1.00E00 regulation of phosphatidylcholine biosynthetic process (GO:2001245) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001239) 40 10 3.95 + 2.53 1.24E-02 2.52E-01 UDP-N-acetylgalactosamine metabolic process (GO:0019276) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of vasculogenesis (GO:2001212) 16 4 1.58 + 2.53 9.91E-02 8.68E-01 vitellogenesis (GO:0007296) 4 1 .40 + 2.53 3.76E-01 1.00E00 midbrain-hindbrain boundary morphogenesis (GO:0021555) 4 1 .40 + 2.53 3.76E-01 1.00E00 lactate biosynthetic process from pyruvate (GO:0019244) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of sarcomere organization (GO:0060298) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of sarcomere organization (GO:0060297) 8 2 .79 + 2.53 2.25E-01 1.00E00 negative regulation of cytoplasmic translation (GO:2000766) 8 2 .79 + 2.53 2.25E-01 1.00E00 metanephric glomerulus vasculature development (GO:0072239) 4 1 .40 + 2.53 3.76E-01 1.00E00 protein kinase C-activating G protein-coupled receptor signaling pathway (GO:0007205) 20 5 1.98 + 2.53 6.84E-02 7.28E-01 monoacylglycerol catabolic process (GO:0052651) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of mesenchymal stem cell differentiation (GO:2000741) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of cell proliferation involved in contact inhibition (GO:0060244) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of eosinophil activation (GO:1902566) 4 1 .40 + 2.53 3.76E-01 1.00E00 delamination (GO:0060232) 4 1 .40 + 2.53 3.76E-01 1.00E00 immunoglobulin production (GO:0002377) 104 26 10.28 + 2.53 8.58E-05 4.53E-03 serotonin production involved in inflammatory response (GO:0002351) 4 1 .40 + 2.53 3.76E-01 1.00E00 B cell affinity maturation (GO:0002344) 4 1 .40 + 2.53 3.76E-01 1.00E00 peripheral B cell selection (GO:0002343) 4 1 .40 + 2.53 3.76E-01 1.00E00 lymphoid progenitor cell differentiation (GO:0002320) 12 3 1.19 + 2.53 1.47E-01 1.00E00 myeloid progenitor cell differentiation (GO:0002318) 8 2 .79 + 2.53 2.25E-01 1.00E00 T cell proliferation involved in immune response (GO:0002309) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of adenylate cyclase activity (GO:0007194) 8 2 .79 + 2.53 2.25E-01 1.00E00 activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171) 4 1 .40 + 2.53 3.76E-01 1.00E00 metanephric tubule morphogenesis (GO:0072173) 8 2 .79 + 2.53 2.25E-01 1.00E00 ubiquitin-dependent protein catabolic process via the C-end degron rule pathway (GO:0140627) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of dopamine receptor signaling pathway (GO:0060161) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of thyroid hormone generation (GO:2000609) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of superoxide anion generation (GO:0032929) 4 1 .40 + 2.53 3.76E-01 1.00E00 platelet activating factor biosynthetic process (GO:0006663) 4 1 .40 + 2.53 3.76E-01 1.00E00 phosphatidylserine biosynthetic process (GO:0006659) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of smooth muscle cell chemotaxis (GO:0071673) 4 1 .40 + 2.53 3.76E-01 1.00E00 triglyceride mobilization (GO:0006642) 4 1 .40 + 2.53 3.76E-01 1.00E00 plasmacytoid dendritic cell activation (GO:0002270) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of granulocyte colony-stimulating factor production (GO:0071655) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of chemokine (C-C motif) ligand 5 production (GO:0071649) 8 2 .79 + 2.53 2.25E-01 1.00E00 positive regulation of transforming growth factor beta production (GO:0071636) 16 4 1.58 + 2.53 9.91E-02 8.67E-01 positive regulation of meiotic cell cycle phase transition (GO:1901995) 4 1 .40 + 2.53 3.76E-01 1.00E00 connective tissue replacement involved in inflammatory response wound healing (GO:0002248) 4 1 .40 + 2.53 3.76E-01 1.00E00 stimulatory C-type lectin receptor signaling pathway (GO:0002223) 4 1 .40 + 2.53 3.76E-01 1.00E00 otic vesicle morphogenesis (GO:0071600) 8 2 .79 + 2.53 2.25E-01 1.00E00 transformation of host cell by virus (GO:0019087) 4 1 .40 + 2.53 3.76E-01 1.00E00 modulation by virus of host cellular process (GO:0019054) 8 2 .79 + 2.53 2.25E-01 1.00E00 viral latency (GO:0019042) 4 1 .40 + 2.53 3.76E-01 1.00E00 male meiosis chromosome segregation (GO:0007060) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of CD8-positive, alpha-beta T cell proliferation (GO:2000566) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of CD8-positive, alpha-beta T cell proliferation (GO:2000564) 8 2 .79 + 2.53 2.25E-01 1.00E00 positive regulation of CD4-positive, alpha-beta T cell proliferation (GO:2000563) 4 1 .40 + 2.53 3.76E-01 1.00E00 collecting duct development (GO:0072044) 8 2 .79 + 2.53 2.25E-01 1.00E00 estrous cycle (GO:0044849) 8 2 .79 + 2.53 2.25E-01 1.00E00 oviduct development (GO:0060066) 4 1 .40 + 2.53 3.76E-01 1.00E00 oncostatin-M-mediated signaling pathway (GO:0038165) 4 1 .40 + 2.53 3.76E-01 1.00E00 distal tubule development (GO:0072017) 8 2 .79 + 2.53 2.25E-01 1.00E00 regulation of immunological synapse formation (GO:2000520) 4 1 .40 + 2.53 3.76E-01 1.00E00 polyamine catabolic process (GO:0006598) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of natural killer cell chemotaxis (GO:2000503) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of natural killer cell chemotaxis (GO:2000501) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation (GO:0032829) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of apoptotic process involved in morphogenesis (GO:1902337) 12 3 1.19 + 2.53 1.47E-01 1.00E00 negative regulation of natural killer cell activation (GO:0032815) 8 2 .79 + 2.53 2.25E-01 1.00E00 protein localization to paranode region of axon (GO:0002175) 4 1 .40 + 2.53 3.76E-01 1.00E00 asparagine metabolic process (GO:0006528) 4 1 .40 + 2.53 3.76E-01 1.00E00 glycoprotein catabolic process (GO:0006516) 20 5 1.98 + 2.53 6.84E-02 7.27E-01 cellular response to lectin (GO:1990858) 4 1 .40 + 2.53 3.76E-01 1.00E00 tRNA wobble position uridine thiolation (GO:0002143) 4 1 .40 + 2.53 3.76E-01 1.00E00 response to lectin (GO:1990840) 4 1 .40 + 2.53 3.76E-01 1.00E00 cellular response to heparin (GO:0071504) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of fibrinolysis (GO:0051918) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of fibrinolysis (GO:0051917) 4 1 .40 + 2.53 3.76E-01 1.00E00 response to vitamin D (GO:0033280) 8 2 .79 + 2.53 2.25E-01 1.00E00 endoplasmic reticulum tubular network membrane organization (GO:1990809) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of high voltage-gated calcium channel activity (GO:1901842) 4 1 .40 + 2.53 3.76E-01 1.00E00 cell-cell junction maintenance (GO:0045217) 16 4 1.58 + 2.53 9.91E-02 8.67E-01 neurotransmitter receptor metabolic process (GO:0045213) 4 1 .40 + 2.53 3.76E-01 1.00E00 modulation of age-related behavioral decline (GO:0090647) 8 2 .79 + 2.53 2.25E-01 1.00E00 semaphorin-plexin signaling pathway involved in neuron projection guidance (GO:1902285) 12 3 1.19 + 2.53 1.47E-01 1.00E00 regulation of monocyte extravasation (GO:2000437) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of interleukin-12 production (GO:0032735) 36 9 3.56 + 2.53 1.72E-02 3.14E-01 positive regulation of T cell extravasation (GO:2000409) 4 1 .40 + 2.53 3.76E-01 1.00E00 reelin-mediated signaling pathway (GO:0038026) 8 2 .79 + 2.53 2.25E-01 1.00E00 regulation of translational termination (GO:0006449) 8 2 .79 + 2.53 2.25E-01 1.00E00 positive regulation of gamma-aminobutyric acid secretion (GO:0014054) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of gamma-aminobutyric acid secretion (GO:0014052) 8 2 .79 + 2.53 2.25E-01 1.00E00 establishment of endothelial blood-brain barrier (GO:0014045) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of neuron maturation (GO:0014043) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of neuron maturation (GO:0014041) 12 3 1.19 + 2.53 1.47E-01 1.00E00 negative regulation of histone ubiquitination (GO:0033183) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of integrin biosynthetic process (GO:0045113) 4 1 .40 + 2.53 3.76E-01 1.00E00 left/right axis specification (GO:0070986) 12 3 1.19 + 2.53 1.47E-01 1.00E00 establishment of endothelial intestinal barrier (GO:0090557) 12 3 1.19 + 2.53 1.47E-01 1.00E00 detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) 8 2 .79 + 2.53 2.25E-01 1.00E00 nuclear-transcribed mRNA catabolic process, no-go decay (GO:0070966) 4 1 .40 + 2.53 3.76E-01 1.00E00 lipid export from cell (GO:0140353) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of interleukin-13 production (GO:0032696) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of interleukin-1 beta production (GO:0032691) 20 5 1.98 + 2.53 6.84E-02 7.27E-01 regulation of interleukin-8 production (GO:0032677) 68 17 6.72 + 2.53 1.64E-03 5.34E-02 cellular response to mineralocorticoid stimulus (GO:0071389) 4 1 .40 + 2.53 3.76E-01 1.00E00 cellular response to interleukin-12 (GO:0071349) 4 1 .40 + 2.53 3.76E-01 1.00E00 cellular response to cocaine (GO:0071314) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of histone H3-K27 acetylation (GO:1901674) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of superoxide dismutase activity (GO:1901671) 4 1 .40 + 2.53 3.76E-01 1.00E00 cellular response to vitamin D (GO:0071305) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of immature T cell proliferation in thymus (GO:0033092) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of immature T cell proliferation in thymus (GO:0033088) 4 1 .40 + 2.53 3.76E-01 1.00E00 cytolysis in other organism (GO:0051715) 4 1 .40 + 2.53 3.76E-01 1.00E00 protein insertion into mitochondrial inner membrane (GO:0045039) 8 2 .79 + 2.53 2.25E-01 1.00E00 positive regulation of myeloid cell apoptotic process (GO:0033034) 8 2 .79 + 2.53 2.25E-01 1.00E00 regulation of mast cell apoptotic process (GO:0033025) 4 1 .40 + 2.53 3.76E-01 1.00E00 secondary metabolite biosynthetic process (GO:0044550) 8 2 .79 + 2.53 2.25E-01 1.00E00 negative regulation of male germ cell proliferation (GO:2000255) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of feeding behavior (GO:2000252) 8 2 .79 + 2.53 2.25E-01 1.00E00 regulation of long-chain fatty acid import into cell (GO:0140212) 8 2 .79 + 2.53 2.25E-01 1.00E00 cellular response to manganese ion (GO:0071287) 4 1 .40 + 2.53 3.76E-01 1.00E00 fatty acid transmembrane transport (GO:1902001) 8 2 .79 + 2.53 2.25E-01 1.00E00 IMP catabolic process (GO:0006204) 4 1 .40 + 2.53 3.76E-01 1.00E00 cellular response to molecule of fungal origin (GO:0071226) 4 1 .40 + 2.53 3.76E-01 1.00E00 cellular response to molecule of bacterial origin (GO:0071219) 152 38 15.03 + 2.53 2.38E-06 2.07E-04 negative regulation of germ cell proliferation (GO:1905937) 4 1 .40 + 2.53 3.76E-01 1.00E00 protein targeting to vacuole involved in autophagy (GO:0071211) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of serotonin uptake (GO:0051612) 4 1 .40 + 2.53 3.76E-01 1.00E00 piRNA biosynthetic process (GO:1990511) 4 1 .40 + 2.53 3.76E-01 1.00E00 D-aspartate import across plasma membrane (GO:0070779) 4 1 .40 + 2.53 3.76E-01 1.00E00 L-aspartate transmembrane transport (GO:0070778) 4 1 .40 + 2.53 3.76E-01 1.00E00 D-aspartate transport (GO:0070777) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process (GO:0140192) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of branching morphogenesis of a nerve (GO:2000173) 4 1 .40 + 2.53 3.76E-01 1.00E00 response to peptidoglycan (GO:0032494) 12 3 1.19 + 2.53 1.47E-01 1.00E00 positive regulation of protein oligomerization (GO:0032461) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of sodium-dependent phosphate transport (GO:2000118) 4 1 .40 + 2.53 3.76E-01 1.00E00 peptidyl-arginine ADP-ribosylation (GO:0018120) 4 1 .40 + 2.53 3.76E-01 1.00E00 adenosine catabolic process (GO:0006154) 4 1 .40 + 2.53 3.76E-01 1.00E00 response to folic acid (GO:0051593) 4 1 .40 + 2.53 3.76E-01 1.00E00 protein citrullination (GO:0018101) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of neurotransmitter uptake (GO:0051581) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of lymphangiogenesis (GO:1901491) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of tetrapyrrole biosynthetic process (GO:1901463) 4 1 .40 + 2.53 3.76E-01 1.00E00 adrenomedullin receptor signaling pathway (GO:1990410) 4 1 .40 + 2.53 3.76E-01 1.00E00 response to interleukin-15 (GO:0070672) 8 2 .79 + 2.53 2.25E-01 1.00E00 negative regulation of spindle checkpoint (GO:0090233) 4 1 .40 + 2.53 3.76E-01 1.00E00 branching morphogenesis of a nerve (GO:0048755) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000096) 8 2 .79 + 2.53 2.25E-01 1.00E00 glucose import in response to insulin stimulus (GO:0044381) 4 1 .40 + 2.53 3.76E-01 1.00E00 astrocyte differentiation (GO:0048708) 52 13 5.14 + 2.53 6.83E-03 1.62E-01 L-aspartate import across plasma membrane (GO:0140009) 4 1 .40 + 2.53 3.76E-01 1.00E00 serine transport (GO:0032329) 8 2 .79 + 2.53 2.25E-01 1.00E00 RNA 3' uridylation (GO:0071076) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of filopodium assembly (GO:0051490) 4 1 .40 + 2.53 3.76E-01 1.00E00 DNA catabolic process, exonucleolytic (GO:0000738) 4 1 .40 + 2.53 3.76E-01 1.00E00 anterograde axonal transport of mitochondrion (GO:0098957) 4 1 .40 + 2.53 3.76E-01 1.00E00 anterograde dendritic transport (GO:0098937) 8 2 .79 + 2.53 2.25E-01 1.00E00 negative regulation of histone H2A K63-linked ubiquitination (GO:1901315) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of histone H2A K63-linked ubiquitination (GO:1901314) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of sprouting of injured axon (GO:0048687) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of sprouting of injured axon (GO:0048686) 4 1 .40 + 2.53 3.76E-01 1.00E00 detection of mechanical stimulus involved in sensory perception of pain (GO:0050966) 16 4 1.58 + 2.53 9.91E-02 8.66E-01 detection of temperature stimulus involved in sensory perception of pain (GO:0050965) 16 4 1.58 + 2.53 9.91E-02 8.66E-01 sensory perception of temperature stimulus (GO:0050951) 20 5 1.98 + 2.53 6.84E-02 7.26E-01 positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway (GO:0106071) 4 1 .40 + 2.53 3.76E-01 1.00E00 central nervous system myelin maintenance (GO:0032286) 4 1 .40 + 2.53 3.76E-01 1.00E00 IMP salvage (GO:0032264) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of inflammatory response to wounding (GO:0106015) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of neurotrophin TRK receptor signaling pathway (GO:0051387) 4 1 .40 + 2.53 3.76E-01 1.00E00 response to mineralocorticoid (GO:0051385) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of hydrogen peroxide-mediated programmed cell death (GO:1901299) 8 2 .79 + 2.53 2.25E-01 1.00E00 regulation of macrophage colony-stimulating factor production (GO:1901256) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of protein deubiquitination (GO:0090086) 4 1 .40 + 2.53 3.76E-01 1.00E00 relaxation of muscle (GO:0090075) 20 5 1.98 + 2.53 6.84E-02 7.26E-01 coumarin metabolic process (GO:0009804) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of deacetylase activity (GO:0090045) 8 2 .79 + 2.53 2.25E-01 1.00E00 regulation of heme biosynthetic process (GO:0070453) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway (GO:0070434) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of pinocytosis (GO:0048549) 8 2 .79 + 2.53 2.25E-01 1.00E00 positive regulation of coagulation (GO:0050820) 20 5 1.98 + 2.53 6.84E-02 7.25E-01 regulation of timing of cell differentiation (GO:0048505) 8 2 .79 + 2.53 2.25E-01 1.00E00 positive regulation of low-density lipoprotein receptor activity (GO:1905599) 4 1 .40 + 2.53 3.76E-01 1.00E00 establishment of meiotic spindle localization (GO:0051295) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of vascular endothelial cell proliferation (GO:1905563) 4 1 .40 + 2.53 3.76E-01 1.00E00 histone H2A phosphorylation (GO:1990164) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) 8 2 .79 + 2.53 2.25E-01 1.00E00 sequestering of metal ion (GO:0051238) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of the force of heart contraction (GO:0098735) 4 1 .40 + 2.53 3.76E-01 1.00E00 macrophage migration (GO:1905517) 16 4 1.58 + 2.53 9.91E-02 8.65E-01 actin polymerization-dependent cell motility (GO:0070358) 4 1 .40 + 2.53 3.76E-01 1.00E00 synaptic vesicle recycling via endosome (GO:0036466) 8 2 .79 + 2.53 2.25E-01 1.00E00 positive regulation of G0 to G1 transition (GO:0070318) 4 1 .40 + 2.53 3.76E-01 1.00E00 hypermethylation of CpG island (GO:0044027) 4 1 .40 + 2.53 3.76E-01 1.00E00 histone citrullination (GO:0036414) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of fatty acid beta-oxidation (GO:0032000) 8 2 .79 + 2.53 2.25E-01 1.00E00 snoRNA guided rRNA pseudouridine synthesis (GO:0000454) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of vascular associated smooth muscle cell apoptotic process (GO:1905460) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of phosphatidylinositol 3-kinase activity (GO:0043553) 4 1 .40 + 2.53 3.76E-01 1.00E00 phenylpropanoid metabolic process (GO:0009698) 4 1 .40 + 2.53 3.76E-01 1.00E00 activation of protein kinase C activity (GO:1990051) 4 1 .40 + 2.53 3.76E-01 1.00E00 RNA import into mitochondrion (GO:0035927) 4 1 .40 + 2.53 3.76E-01 1.00E00 ascending aorta morphogenesis (GO:0035910) 4 1 .40 + 2.53 3.76E-01 1.00E00 renal sodium ion absorption (GO:0070294) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of leukocyte adhesion to vascular endothelial cell (GO:1904995) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of lymphocyte proliferation (GO:0050670) 216 54 21.36 + 2.53 1.87E-08 2.84E-06 hydrogen peroxide biosynthetic process (GO:0050665) 8 2 .79 + 2.53 2.25E-01 1.00E00 regulation of activation-induced cell death of T cells (GO:0070235) 8 2 .79 + 2.53 2.25E-01 1.00E00 positive regulation of endothelial cell-matrix adhesion via fibronectin (GO:1904906) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of endothelial cell-matrix adhesion via fibronectin (GO:1904904) 4 1 .40 + 2.53 3.76E-01 1.00E00 modulation by symbiont of host autophagy (GO:0075071) 8 2 .79 + 2.53 2.25E-01 1.00E00 positive regulation by symbiont of host autophagy (GO:0075044) 8 2 .79 + 2.53 2.25E-01 1.00E00 regulation of membrane protein ectodomain proteolysis (GO:0051043) 20 5 1.98 + 2.53 6.84E-02 7.25E-01 positive regulation of amyloid precursor protein biosynthetic process (GO:0042986) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of adiponectin secretion (GO:0070164) 4 1 .40 + 2.53 3.76E-01 1.00E00 macrophage chemotaxis (GO:0048246) 12 3 1.19 + 2.53 1.47E-01 1.00E00 epinephrine transport (GO:0048241) 4 1 .40 + 2.53 3.76E-01 1.00E00 multivesicular body organization (GO:0036257) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030949) 12 3 1.19 + 2.53 1.47E-01 1.00E00 positive regulation of long-term synaptic depression (GO:1900454) 8 2 .79 + 2.53 2.25E-01 1.00E00 allantoin metabolic process (GO:0000255) 8 2 .79 + 2.53 2.25E-01 1.00E00 positive regulation of memory T cell differentiation (GO:0043382) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of CAMKK-AMPK signaling cascade (GO:1905289) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of CD8-positive, alpha-beta T cell differentiation (GO:0043378) 4 1 .40 + 2.53 3.76E-01 1.00E00 endothelial cell chemotaxis (GO:0035767) 8 2 .79 + 2.53 2.25E-01 1.00E00 CD4-positive, alpha-beta T cell lineage commitment (GO:0043373) 16 4 1.58 + 2.53 9.91E-02 8.65E-01 regulation of modification of postsynaptic actin cytoskeleton (GO:1905274) 8 2 .79 + 2.53 2.25E-01 1.00E00 B cell chemotaxis (GO:0035754) 4 1 .40 + 2.53 3.76E-01 1.00E00 common myeloid progenitor cell proliferation (GO:0035726) 8 2 .79 + 2.53 2.25E-01 1.00E00 cellular response to L-glutamate (GO:1905232) 4 1 .40 + 2.53 3.76E-01 1.00E00 arachidonic acid secretion (GO:0050482) 12 3 1.19 + 2.53 1.47E-01 1.00E00 negative regulation of myeloid dendritic cell activation (GO:0030886) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of apoptotic process involved in development (GO:1904748) 12 3 1.19 + 2.53 1.47E-01 1.00E00 phosphatidylcholine acyl-chain remodeling (GO:0036151) 12 3 1.19 + 2.53 1.47E-01 1.00E00 phosphatidylserine acyl-chain remodeling (GO:0036150) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of mRNA polyadenylation (GO:1900365) 4 1 .40 + 2.53 3.76E-01 1.00E00 articular cartilage development (GO:0061975) 4 1 .40 + 2.53 3.76E-01 1.00E00 activation of MAPKKK activity (GO:0000185) 8 2 .79 + 2.53 2.25E-01 1.00E00 maintenance of blood-brain barrier (GO:0035633) 16 4 1.58 + 2.53 9.91E-02 8.64E-01 negative regulation of metalloendopeptidase activity (GO:1904684) 4 1 .40 + 2.53 3.76E-01 1.00E00 hydrogen peroxide metabolic process (GO:0042743) 32 8 3.16 + 2.53 2.41E-02 3.91E-01 cellular response to phorbol 13-acetate 12-myristate (GO:1904628) 4 1 .40 + 2.53 3.76E-01 1.00E00 response to phorbol 13-acetate 12-myristate (GO:1904627) 4 1 .40 + 2.53 3.76E-01 1.00E00 Tie signaling pathway (GO:0048014) 4 1 .40 + 2.53 3.76E-01 1.00E00 hepatocyte growth factor receptor signaling pathway (GO:0048012) 8 2 .79 + 2.53 2.25E-01 1.00E00 sequestering of triglyceride (GO:0030730) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of NLRP3 inflammasome complex assembly (GO:1900227) 8 2 .79 + 2.53 2.25E-01 1.00E00 regulation of mini excitatory postsynaptic potential (GO:0061884) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of cardiac muscle contraction (GO:0055118) 4 1 .40 + 2.53 3.76E-01 1.00E00 stress fiber assembly (GO:0043149) 16 4 1.58 + 2.53 9.91E-02 8.64E-01 regulation of antifungal innate immune response (GO:1905034) 4 1 .40 + 2.53 3.76E-01 1.00E00 long-chain fatty acid import across plasma membrane (GO:0015911) 4 1 .40 + 2.53 3.76E-01 1.00E00 long-chain fatty acid import into peroxisome (GO:0015910) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of intracellular mRNA localization (GO:1904580) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of cell fate specification (GO:0042660) 4 1 .40 + 2.53 3.76E-01 1.00E00 anagen (GO:0042640) 8 2 .79 + 2.53 2.25E-01 1.00E00 membrane tubulation (GO:0097749) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of bone mineralization involved in bone maturation (GO:1900157) 4 1 .40 + 2.53 3.76E-01 1.00E00 connective tissue replacement (GO:0097709) 4 1 .40 + 2.53 3.76E-01 1.00E00 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of hyaluronan biosynthetic process (GO:1900126) 4 1 .40 + 2.53 3.76E-01 1.00E00 CAMKK-AMPK signaling cascade (GO:0061762) 4 1 .40 + 2.53 3.76E-01 1.00E00 protein lipidation involved in autophagosome assembly (GO:0061739) 4 1 .40 + 2.53 3.76E-01 1.00E00 norepinephrine transport (GO:0015874) 4 1 .40 + 2.53 3.76E-01 1.00E00 cell migration involved in vasculogenesis (GO:0035441) 4 1 .40 + 2.53 3.76E-01 1.00E00 purine nucleoside transmembrane transport (GO:0015860) 4 1 .40 + 2.53 3.76E-01 1.00E00 extracellular matrix-cell signaling (GO:0035426) 4 1 .40 + 2.53 3.76E-01 1.00E00 urea transport (GO:0015840) 4 1 .40 + 2.53 3.76E-01 1.00E00 purine deoxyribonucleoside monophosphate metabolic process (GO:0009170) 8 2 .79 + 2.53 2.25E-01 1.00E00 amine transport (GO:0015837) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of intestinal absorption (GO:1904478) 8 2 .79 + 2.53 2.25E-01 1.00E00 neuron maturation (GO:0042551) 32 8 3.16 + 2.53 2.41E-02 3.90E-01 folate import across plasma membrane (GO:1904447) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of SMAD protein complex assembly (GO:0010991) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of ceramide biosynthetic process (GO:1900060) 4 1 .40 + 2.53 3.76E-01 1.00E00 monounsaturated fatty acid biosynthetic process (GO:1903966) 4 1 .40 + 2.53 3.76E-01 1.00E00 monounsaturated fatty acid metabolic process (GO:1903964) 4 1 .40 + 2.53 3.76E-01 1.00E00 arachidonate transport (GO:1903963) 12 3 1.19 + 2.53 1.47E-01 1.00E00 cellular response to sodium arsenite (GO:1903936) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of establishment of T cell polarity (GO:1903903) 4 1 .40 + 2.53 3.76E-01 1.00E00 SA node cell to atrial cardiac muscle cell communication (GO:0086070) 4 1 .40 + 2.53 3.76E-01 1.00E00 prostaglandin transport (GO:0015732) 4 1 .40 + 2.53 3.76E-01 1.00E00 membrane depolarization during AV node cell action potential (GO:0086045) 4 1 .40 + 2.53 3.76E-01 1.00E00 SA node cell to atrial cardiac muscle cell signaling (GO:0086018) 4 1 .40 + 2.53 3.76E-01 1.00E00 SA node cell action potential (GO:0086015) 4 1 .40 + 2.53 3.76E-01 1.00E00 detection of bacterial lipoprotein (GO:0042494) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of cardiac epithelial to mesenchymal transition (GO:0062042) 8 2 .79 + 2.53 2.25E-01 1.00E00 positive regulation of mitotic sister chromatid segregation (GO:0062033) 4 1 .40 + 2.53 3.76E-01 1.00E00 hormone catabolic process (GO:0042447) 8 2 .79 + 2.53 2.25E-01 1.00E00 negative regulation of triglyceride catabolic process (GO:0010897) 4 1 .40 + 2.53 3.76E-01 1.00E00 axon midline choice point recognition (GO:0016199) 4 1 .40 + 2.53 3.76E-01 1.00E00 sleep (GO:0030431) 8 2 .79 + 2.53 2.25E-01 1.00E00 T cell chemotaxis (GO:0010818) 8 2 .79 + 2.53 2.25E-01 1.00E00 trigeminal ganglion development (GO:0061551) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of oxidative phosphorylation (GO:1903862) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of aorta morphogenesis (GO:1903849) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of aorta morphogenesis (GO:1903847) 4 1 .40 + 2.53 3.76E-01 1.00E00 amyloid-beta clearance by cellular catabolic process (GO:0150094) 8 2 .79 + 2.53 2.25E-01 1.00E00 hypoxia-inducible factor-1alpha signaling pathway (GO:0097411) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of plasminogen activation (GO:0010756) 4 1 .40 + 2.53 3.76E-01 1.00E00 poly-N-acetyllactosamine biosynthetic process (GO:0030311) 12 3 1.19 + 2.53 1.47E-01 1.00E00 poly-N-acetyllactosamine metabolic process (GO:0030309) 12 3 1.19 + 2.53 1.47E-01 1.00E00 regulation of definitive erythrocyte differentiation (GO:0010724) 4 1 .40 + 2.53 3.76E-01 1.00E00 RIG-I signaling pathway (GO:0039529) 8 2 .79 + 2.53 2.25E-01 1.00E00 modulation by virus of host apoptotic process (GO:0039526) 4 1 .40 + 2.53 3.76E-01 1.00E00 lipid tube assembly (GO:0060988) 4 1 .40 + 2.53 3.76E-01 1.00E00 endocrine hormone secretion (GO:0060986) 8 2 .79 + 2.53 2.25E-01 1.00E00 cell migration involved in heart development (GO:0060973) 12 3 1.19 + 2.53 1.47E-01 1.00E00 regulation of retinal cell programmed cell death (GO:0046668) 4 1 .40 + 2.53 3.76E-01 1.00E00 response to gonadotropin (GO:0034698) 8 2 .79 + 2.53 2.25E-01 1.00E00 sinoatrial node cell development (GO:0060931) 4 1 .40 + 2.53 3.76E-01 1.00E00 cardiac muscle cell fate commitment (GO:0060923) 4 1 .40 + 2.53 3.76E-01 1.00E00 L-histidine transmembrane transport (GO:0089709) 4 1 .40 + 2.53 3.76E-01 1.00E00 germ cell migration (GO:0008354) 8 2 .79 + 2.53 2.25E-01 1.00E00 positive regulation of cholesterol import (GO:1904109) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of cell communication by electrical coupling (GO:0010649) 8 2 .79 + 2.53 2.25E-01 1.00E00 cell adhesion involved in heart morphogenesis (GO:0061343) 4 1 .40 + 2.53 3.76E-01 1.00E00 nuclear speck organization (GO:0035063) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of protein tyrosine phosphatase activity (GO:1903613) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of locomotor rhythm (GO:1904059) 4 1 .40 + 2.53 3.76E-01 1.00E00 spermidine biosynthetic process (GO:0008295) 4 1 .40 + 2.53 3.76E-01 1.00E00 hematopoietic stem cell migration to bone marrow (GO:0097241) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of lung blood pressure (GO:0014916) 4 1 .40 + 2.53 3.76E-01 1.00E00 myoblast fusion involved in skeletal muscle regeneration (GO:0014905) 4 1 .40 + 2.53 3.76E-01 1.00E00 natural killer cell activation (GO:0030101) 40 10 3.95 + 2.53 1.24E-02 2.52E-01 negative regulation of calcium ion transport into cytosol (GO:0010523) 12 3 1.19 + 2.53 1.47E-01 1.00E00 negative regulation of B cell apoptotic process (GO:0002903) 12 3 1.19 + 2.53 1.47E-01 1.00E00 positive regulation of extracellular exosome assembly (GO:1903553) 4 1 .40 + 2.53 3.76E-01 1.00E00 branch elongation involved in mammary gland duct branching (GO:0060751) 4 1 .40 + 2.53 3.76E-01 1.00E00 cellular response to cisplatin (GO:0072719) 4 1 .40 + 2.53 3.76E-01 1.00E00 chorio-allantoic fusion (GO:0060710) 8 2 .79 + 2.53 2.25E-01 1.00E00 spongiotrophoblast differentiation (GO:0060708) 4 1 .40 + 2.53 3.76E-01 1.00E00 ammonium ion metabolic process (GO:0097164) 20 5 1.98 + 2.53 6.84E-02 7.24E-01 glycoprotein transport (GO:0034436) 4 1 .40 + 2.53 3.76E-01 1.00E00 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration (GO:0014834) 4 1 .40 + 2.53 3.76E-01 1.00E00 gastro-intestinal system smooth muscle contraction (GO:0014831) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of acute inflammatory response to antigenic stimulus (GO:0002865) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of natural killer cell mediated cytotoxicity directed against tumor cell target (GO:0002858) 8 2 .79 + 2.53 2.25E-01 1.00E00 neuroligin clustering involved in postsynaptic membrane assembly (GO:0097118) 4 1 .40 + 2.53 3.76E-01 1.00E00 gephyrin clustering involved in postsynaptic density assembly (GO:0097116) 4 1 .40 + 2.53 3.76E-01 1.00E00 contractile actin filament bundle assembly (GO:0030038) 16 4 1.58 + 2.53 9.91E-02 8.63E-01 microspike assembly (GO:0030035) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of somitogenesis (GO:0014807) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of type 2 immune response (GO:0002830) 16 4 1.58 + 2.53 9.91E-02 8.63E-01 positive regulation of translational elongation (GO:0045901) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of translational elongation (GO:0045900) 4 1 .40 + 2.53 3.76E-01 1.00E00 positive regulation of cell maturation (GO:1903431) 8 2 .79 + 2.53 2.25E-01 1.00E00 hindbrain radial glia guided cell migration (GO:0021932) 12 3 1.19 + 2.53 1.47E-01 1.00E00 T cell migration (GO:0072678) 20 5 1.98 + 2.53 6.84E-02 7.24E-01 atrial septum primum morphogenesis (GO:0003289) 4 1 .40 + 2.53 3.76E-01 1.00E00 septum primum development (GO:0003284) 4 1 .40 + 2.53 3.76E-01 1.00E00 cell migration involved in endocardial cushion formation (GO:0003273) 4 1 .40 + 2.53 3.76E-01 1.00E00 regulation of cardioblast proliferation (GO:0003264) 12 3 1.19 + 2.53 1.47E-01 1.00E00 negative regulation of amyloid precursor protein catabolic process (GO:1902992) 20 5 1.98 + 2.53 6.84E-02 7.23E-01 positive regulation of smooth muscle cell apoptotic process (GO:0034393) 12 3 1.19 + 2.53 1.47E-01 1.00E00 chylomicron remnant clearance (GO:0034382) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of dendritic spine maintenance (GO:1902951) 4 1 .40 + 2.53 3.76E-01 1.00E00 ductus arteriosus closure (GO:0097070) 4 1 .40 + 2.53 3.76E-01 1.00E00 glial cell apoptotic process (GO:0034349) 4 1 .40 + 2.53 3.76E-01 1.00E00 MyD88-independent toll-like receptor signaling pathway (GO:0002756) 12 3 1.19 + 2.53 1.47E-01 1.00E00 hypothalamus gonadotrophin-releasing hormone neuron development (GO:0021888) 4 1 .40 + 2.53 3.76E-01 1.00E00 hypothalamus gonadotrophin-releasing hormone neuron differentiation (GO:0021886) 4 1 .40 + 2.53 3.76E-01 1.00E00 forebrain ventricular zone progenitor cell division (GO:0021869) 4 1 .40 + 2.53 3.76E-01 1.00E00 forebrain radial glial cell differentiation (GO:0021861) 8 2 .79 + 2.53 2.25E-01 1.00E00 hypothalamus cell migration (GO:0021855) 4 1 .40 + 2.53 3.76E-01 1.00E00 endocardial cushion to mesenchymal transition involved in heart valve formation (GO:0003199) 4 1 .40 + 2.53 3.76E-01 1.00E00 mitral valve formation (GO:0003192) 4 1 .40 + 2.53 3.76E-01 1.00E00 neurotransmitter-gated ion channel clustering (GO:0072578) 8 2 .79 + 2.53 2.25E-01 1.00E00 cell fate commitment involved in pattern specification (GO:0060581) 4 1 .40 + 2.53 3.76E-01 1.00E00 atrioventricular node development (GO:0003162) 4 1 .40 + 2.53 3.76E-01 1.00E00 ventral spinal cord interneuron fate commitment (GO:0060579) 4 1 .40 + 2.53 3.76E-01 1.00E00 T-helper 17 cell differentiation (GO:0072539) 12 3 1.19 + 2.53 1.47E-01 1.00E00 positive regulation of glomerular filtration (GO:0003104) 4 1 .40 + 2.53 3.76E-01 1.00E00 negative regulation of cellular extravasation (GO:0002692) 8 2 .79 + 2.53 2.25E-01 1.00E00 positive regulation of lipid kinase activity (GO:0090218) 28 7 2.77 + 2.53 3.38E-02 4.87E-01 positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) 28 7 2.77 + 2.53 3.38E-02 4.87E-01 antimicrobial humoral immune response mediated by antimicrobial peptide (GO:0061844) 44 11 4.35 + 2.53 1.45E-02 2.74E-01 T cell proliferation (GO:0042098) 44 11 4.35 + 2.53 1.45E-02 2.74E-01 immune response (GO:0006955) 1102 274 108.96 + 2.51 1.62E-39 1.23E-35 myeloid leukocyte differentiation (GO:0002573) 113 28 11.17 + 2.51 7.42E-05 4.09E-03 regulation of mononuclear cell proliferation (GO:0032944) 218 54 21.55 + 2.51 2.31E-08 3.40E-06 negative regulation of leukocyte apoptotic process (GO:2000107) 53 13 5.24 + 2.48 7.32E-03 1.71E-01 negative regulation of actin filament polymerization (GO:0030837) 53 13 5.24 + 2.48 7.32E-03 1.71E-01 positive regulation of myeloid cell differentiation (GO:0045639) 98 24 9.69 + 2.48 3.23E-04 1.42E-02 myeloid cell differentiation (GO:0030099) 233 57 23.04 + 2.47 1.70E-08 2.60E-06 regulation of leukocyte apoptotic process (GO:2000106) 90 22 8.90 + 2.47 3.88E-04 1.64E-02 regulation of macrophage migration (GO:1905521) 41 10 4.05 + 2.47 2.23E-02 3.70E-01 negative regulation of epithelial cell apoptotic process (GO:1904036) 41 10 4.05 + 2.47 2.23E-02 3.69E-01 regulation of leukocyte migration (GO:0002685) 197 48 19.48 + 2.46 2.16E-07 2.64E-05 cell activation involved in immune response (GO:0002263) 152 37 15.03 + 2.46 8.00E-06 6.32E-04 T cell differentiation involved in immune response (GO:0002292) 37 9 3.66 + 2.46 1.97E-02 3.42E-01 cellular response to lipopolysaccharide (GO:0071222) 144 35 14.24 + 2.46 9.55E-06 7.36E-04 positive regulation of leukocyte proliferation (GO:0070665) 140 34 13.84 + 2.46 1.31E-05 9.44E-04 positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) 33 8 3.26 + 2.45 2.76E-02 4.32E-01 long-chain fatty acid transport (GO:0015909) 33 8 3.26 + 2.45 2.76E-02 4.31E-01 cellular response to interleukin-1 (GO:0071347) 62 15 6.13 + 2.45 3.93E-03 1.04E-01 superoxide metabolic process (GO:0006801) 29 7 2.87 + 2.44 3.88E-02 5.35E-01 negative regulation of cell junction assembly (GO:1901889) 29 7 2.87 + 2.44 3.88E-02 5.35E-01 amine biosynthetic process (GO:0009309) 29 7 2.87 + 2.44 3.88E-02 5.34E-01 cellular biogenic amine biosynthetic process (GO:0042401) 29 7 2.87 + 2.44 3.88E-02 5.34E-01 negative regulation of T cell activation (GO:0050868) 112 27 11.07 + 2.44 1.29E-04 6.39E-03 response to other organism (GO:0051707) 992 239 98.08 + 2.44 3.05E-32 9.27E-29 response to external biotic stimulus (GO:0043207) 992 239 98.08 + 2.44 3.05E-32 7.73E-29 positive regulation of immune system process (GO:0002684) 789 190 78.01 + 2.44 1.36E-25 1.72E-22 response to ATP (GO:0033198) 25 6 2.47 + 2.43 5.50E-02 6.40E-01 regulation of phospholipase activity (GO:0010517) 50 12 4.94 + 2.43 1.13E-02 2.37E-01 regulation of production of molecular mediator of immune response (GO:0002700) 146 35 14.44 + 2.42 1.77E-05 1.19E-03 response to molecule of bacterial origin (GO:0002237) 238 57 23.53 + 2.42 2.62E-08 3.82E-06 regulation of leukocyte proliferation (GO:0070663) 230 55 22.74 + 2.42 4.98E-08 6.74E-06 regulation of actin filament depolymerization (GO:0030834) 46 11 4.55 + 2.42 1.63E-02 3.00E-01 positive regulation of G protein-coupled receptor signaling pathway (GO:0045745) 21 5 2.08 + 2.41 7.87E-02 7.94E-01 positive regulation of nitric oxide biosynthetic process (GO:0045429) 42 10 4.15 + 2.41 2.35E-02 3.85E-01 acetylcholine receptor signaling pathway (GO:0095500) 21 5 2.08 + 2.41 7.87E-02 7.93E-01 response to vitamin (GO:0033273) 21 5 2.08 + 2.41 7.87E-02 7.93E-01 regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902041) 42 10 4.15 + 2.41 2.35E-02 3.85E-01 negative regulation of potassium ion transmembrane transport (GO:1901380) 21 5 2.08 + 2.41 7.87E-02 7.92E-01 negative regulation of oxidoreductase activity (GO:0051354) 21 5 2.08 + 2.41 7.87E-02 7.92E-01 lens fiber cell differentiation (GO:0070306) 21 5 2.08 + 2.41 7.87E-02 7.91E-01 Rac protein signal transduction (GO:0016601) 21 5 2.08 + 2.41 7.87E-02 7.91E-01 potassium ion homeostasis (GO:0055075) 21 5 2.08 + 2.41 7.87E-02 7.90E-01 positive regulation of alpha-beta T cell proliferation (GO:0046641) 21 5 2.08 + 2.41 7.87E-02 7.90E-01 regulation of mononuclear cell migration (GO:0071675) 101 24 9.99 + 2.40 3.85E-04 1.63E-02 response to interleukin-1 (GO:0070555) 76 18 7.51 + 2.40 1.76E-03 5.60E-02 regulation of vascular permeability (GO:0043114) 38 9 3.76 + 2.40 3.43E-02 4.91E-01 response to biotic stimulus (GO:0009607) 1024 242 101.24 + 2.39 1.18E-31 2.56E-28 positive regulation of cytokine production (GO:0001819) 419 99 41.43 + 2.39 3.58E-13 1.01E-10 negative regulation of leukocyte cell-cell adhesion (GO:1903038) 123 29 12.16 + 2.38 8.85E-05 4.65E-03 negative regulation of systemic arterial blood pressure (GO:0003085) 17 4 1.68 + 2.38 1.14E-01 9.39E-01 negative regulation of lymphocyte differentiation (GO:0045620) 51 12 5.04 + 2.38 1.22E-02 2.50E-01 regulation of podosome assembly (GO:0071801) 17 4 1.68 + 2.38 1.14E-01 9.39E-01 L-alpha-amino acid transmembrane transport (GO:1902475) 34 8 3.36 + 2.38 5.05E-02 6.07E-01 positive regulation by host of viral process (GO:0044794) 17 4 1.68 + 2.38 1.14E-01 9.38E-01 positive regulation of interleukin-1 beta production (GO:0032731) 51 12 5.04 + 2.38 1.22E-02 2.49E-01 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902236) 17 4 1.68 + 2.38 1.14E-01 9.38E-01 response to lipopolysaccharide (GO:0032496) 221 52 21.85 + 2.38 1.73E-07 2.19E-05 detection of temperature stimulus involved in sensory perception (GO:0050961) 17 4 1.68 + 2.38 1.14E-01 9.37E-01 myelin maintenance (GO:0043217) 17 4 1.68 + 2.38 1.14E-01 9.37E-01 vesicle transport along actin filament (GO:0030050) 17 4 1.68 + 2.38 1.14E-01 9.36E-01 negative regulation of smooth muscle contraction (GO:0045986) 17 4 1.68 + 2.38 1.14E-01 9.36E-01 cellular anion homeostasis (GO:0030002) 17 4 1.68 + 2.38 1.14E-01 9.35E-01 regulation of cytokine production involved in immune response (GO:0002718) 85 20 8.40 + 2.38 1.54E-03 5.14E-02 leukocyte activation involved in immune response (GO:0002366) 149 35 14.73 + 2.38 2.13E-05 1.39E-03 positive regulation of immunoglobulin production (GO:0002639) 47 11 4.65 + 2.37 1.74E-02 3.17E-01 positive regulation of regulated secretory pathway (GO:1903307) 47 11 4.65 + 2.37 1.74E-02 3.17E-01 cellular response to interferon-gamma (GO:0071346) 77 18 7.61 + 2.36 1.97E-03 6.10E-02 regulation of immune response (GO:0050776) 685 160 67.73 + 2.36 2.65E-20 1.91E-17 detection of biotic stimulus (GO:0009595) 30 7 2.97 + 2.36 4.43E-02 5.56E-01 positive regulation of T cell proliferation (GO:0042102) 90 21 8.90 + 2.36 1.15E-03 4.08E-02 regulation of type 2 immune response (GO:0002828) 30 7 2.97 + 2.36 4.43E-02 5.56E-01 positive regulation of production of molecular mediator of immune response (GO:0002702) 103 24 10.18 + 2.36 4.50E-04 1.87E-02 regulation of glycolytic process (GO:0006110) 43 10 4.25 + 2.35 2.51E-02 4.01E-01 positive regulation of nitric oxide metabolic process (GO:1904407) 43 10 4.25 + 2.35 2.51E-02 4.01E-01 regulation of plasma lipoprotein particle levels (GO:0097006) 43 10 4.25 + 2.35 2.51E-02 4.00E-01 positive regulation of angiogenesis (GO:0045766) 147 34 14.53 + 2.34 3.45E-05 2.15E-03 positive regulation of vasculature development (GO:1904018) 147 34 14.53 + 2.34 3.45E-05 2.14E-03 cellular response to biotic stimulus (GO:0071216) 173 40 17.10 + 2.34 8.85E-06 6.92E-04 modulation of process of other organism (GO:0035821) 91 21 9.00 + 2.33 1.23E-03 4.31E-02 positive regulation of osteoblast proliferation (GO:0033690) 13 3 1.29 + 2.33 1.69E-01 1.00E00 regulation of steroid hormone secretion (GO:2000831) 13 3 1.29 + 2.33 1.69E-01 1.00E00 calcium ion import into cytosol (GO:1902656) 13 3 1.29 + 2.33 1.69E-01 1.00E00 serotonin transport (GO:0006837) 13 3 1.29 + 2.33 1.69E-01 1.00E00 iron ion transport (GO:0006826) 39 9 3.86 + 2.33 3.63E-02 5.08E-01 mast cell activation (GO:0045576) 26 6 2.57 + 2.33 6.28E-02 7.07E-01 I-kappaB phosphorylation (GO:0007252) 13 3 1.29 + 2.33 1.69E-01 1.00E00 metanephric tubule development (GO:0072170) 13 3 1.29 + 2.33 1.69E-01 1.00E00 T-helper cell lineage commitment (GO:0002295) 13 3 1.29 + 2.33 1.69E-01 1.00E00 negative regulation of monooxygenase activity (GO:0032769) 13 3 1.29 + 2.33 1.69E-01 1.00E00 actin filament network formation (GO:0051639) 13 3 1.29 + 2.33 1.69E-01 1.00E00 positive regulation of keratinocyte migration (GO:0051549) 13 3 1.29 + 2.33 1.69E-01 1.00E00 cellular response to leptin stimulus (GO:0044320) 13 3 1.29 + 2.33 1.69E-01 1.00E00 icosanoid secretion (GO:0032309) 13 3 1.29 + 2.33 1.69E-01 1.00E00 positive regulation of T cell apoptotic process (GO:0070234) 13 3 1.29 + 2.33 1.69E-01 1.00E00 interleukin-6-mediated signaling pathway (GO:0070102) 13 3 1.29 + 2.33 1.69E-01 1.00E00 regulation of long-term neuronal synaptic plasticity (GO:0048169) 26 6 2.57 + 2.33 6.28E-02 7.06E-01 leukocyte degranulation (GO:0043299) 26 6 2.57 + 2.33 6.28E-02 7.06E-01 ribonucleoside monophosphate catabolic process (GO:0009158) 13 3 1.29 + 2.33 1.69E-01 1.00E00 detection of stimulus involved in sensory perception of pain (GO:0062149) 26 6 2.57 + 2.33 6.28E-02 7.05E-01 regulation of amino acid import across plasma membrane (GO:0010958) 13 3 1.29 + 2.33 1.69E-01 1.00E00 negative regulation of protein processing (GO:0010955) 26 6 2.57 + 2.33 6.28E-02 7.05E-01 positive regulation of ruffle assembly (GO:1900029) 13 3 1.29 + 2.33 1.69E-01 1.00E00 negative regulation of viral life cycle (GO:1903901) 26 6 2.57 + 2.33 6.28E-02 7.04E-01 positive regulation of peptidyl-threonine phosphorylation (GO:0010800) 26 6 2.57 + 2.33 6.28E-02 7.04E-01 regulation of amino acid transmembrane transport (GO:1903789) 13 3 1.29 + 2.33 1.69E-01 1.00E00 renal filtration (GO:0097205) 13 3 1.29 + 2.33 1.69E-01 1.00E00 actin filament polymerization (GO:0030041) 26 6 2.57 + 2.33 6.28E-02 7.03E-01 negative regulation of type 2 immune response (GO:0002829) 13 3 1.29 + 2.33 1.69E-01 1.00E00 short-term memory (GO:0007614) 13 3 1.29 + 2.33 1.69E-01 1.00E00 embryonic placenta morphogenesis (GO:0060669) 26 6 2.57 + 2.33 6.28E-02 7.03E-01 negative regulation of protein maturation (GO:1903318) 26 6 2.57 + 2.33 6.28E-02 7.02E-01 cardiac conduction system development (GO:0003161) 13 3 1.29 + 2.33 1.69E-01 1.00E00 T-helper 17 type immune response (GO:0072538) 13 3 1.29 + 2.33 1.69E-01 1.00E00 positive regulation of ERK1 and ERK2 cascade (GO:0070374) 174 40 17.20 + 2.33 9.34E-06 7.23E-04 biological process involved in interspecies interaction between organisms (GO:0044419) 1092 251 107.97 + 2.32 2.97E-31 5.63E-28 cellular response to chemokine (GO:1990869) 48 11 4.75 + 2.32 1.88E-02 3.32E-01 response to chemokine (GO:1990868) 48 11 4.75 + 2.32 1.88E-02 3.32E-01 positive regulation of protein kinase B signaling (GO:0051897) 96 22 9.49 + 2.32 9.46E-04 3.45E-02 regulation of immune system process (GO:0002682) 1205 276 119.14 + 2.32 1.87E-34 7.10E-31 positive regulation of chemotaxis (GO:0050921) 131 30 12.95 + 2.32 1.29E-04 6.41E-03 regulation of phosphatidylinositol 3-kinase activity (GO:0043551) 35 8 3.46 + 2.31 5.30E-02 6.32E-01 negative regulation of tumor necrosis factor production (GO:0032720) 57 13 5.64 + 2.31 1.02E-02 2.23E-01 negative regulation of mononuclear cell proliferation (GO:0032945) 79 18 7.81 + 2.30 3.45E-03 9.53E-02 negative regulation of lymphocyte proliferation (GO:0050672) 79 18 7.81 + 2.30 3.45E-03 9.52E-02 positive regulation of bone resorption (GO:0045780) 22 5 2.18 + 2.30 8.98E-02 8.44E-01 positive regulation of fatty acid biosynthetic process (GO:0045723) 22 5 2.18 + 2.30 8.98E-02 8.44E-01 production of molecular mediator involved in inflammatory response (GO:0002532) 22 5 2.18 + 2.30 8.98E-02 8.43E-01 positive regulation of interferon-alpha production (GO:0032727) 22 5 2.18 + 2.30 8.98E-02 8.43E-01 glucosamine-containing compound metabolic process (GO:1901071) 22 5 2.18 + 2.30 8.98E-02 8.42E-01 cellular response to drug (GO:0035690) 44 10 4.35 + 2.30 2.69E-02 4.21E-01 neuron projection regeneration (GO:0031102) 22 5 2.18 + 2.30 8.98E-02 8.42E-01 hair follicle morphogenesis (GO:0031069) 22 5 2.18 + 2.30 8.98E-02 8.41E-01 regulation of cell maturation (GO:1903429) 22 5 2.18 + 2.30 8.98E-02 8.41E-01 immune system process (GO:0002376) 1813 412 179.25 + 2.30 3.74E-53 5.67E-49 pattern recognition receptor signaling pathway (GO:0002221) 75 17 7.42 + 2.29 4.89E-03 1.23E-01 positive regulation of cold-induced thermogenesis (GO:0120162) 84 19 8.31 + 2.29 2.59E-03 7.61E-02 catecholamine metabolic process (GO:0006584) 31 7 3.07 + 2.28 7.79E-02 7.88E-01 catechol-containing compound metabolic process (GO:0009712) 31 7 3.07 + 2.28 7.79E-02 7.87E-01 negative regulation of exocytosis (GO:0045920) 31 7 3.07 + 2.28 7.79E-02 7.87E-01 regulation of immunoglobulin production (GO:0002637) 71 16 7.02 + 2.28 6.96E-03 1.64E-01 iron ion homeostasis (GO:0055072) 71 16 7.02 + 2.28 6.96E-03 1.64E-01 cellular response to inorganic substance (GO:0071241) 151 34 14.93 + 2.28 7.43E-05 4.07E-03 negative regulation of defense response (GO:0031348) 191 43 18.88 + 2.28 7.97E-06 6.34E-04 positive regulation of interferon-beta production (GO:0032728) 40 9 3.95 + 2.28 3.87E-02 5.35E-01 L-amino acid transport (GO:0015807) 40 9 3.95 + 2.28 3.87E-02 5.34E-01 negative regulation of cell-substrate adhesion (GO:0010812) 49 11 4.84 + 2.27 2.04E-02 3.50E-01 positive regulation of response to cytokine stimulus (GO:0060760) 49 11 4.84 + 2.27 2.04E-02 3.50E-01 negative regulation of tumor necrosis factor superfamily cytokine production (GO:1903556) 58 13 5.73 + 2.27 1.12E-02 2.37E-01 coagulation (GO:0050817) 94 21 9.29 + 2.26 1.55E-03 5.14E-02 blood coagulation (GO:0007596) 94 21 9.29 + 2.26 1.55E-03 5.13E-02 regulation of cell shape (GO:0008360) 139 31 13.74 + 2.26 1.27E-04 6.36E-03 modified amino acid transport (GO:0072337) 27 6 2.67 + 2.25 1.16E-01 9.44E-01 regulation of coagulation (GO:0050818) 54 12 5.34 + 2.25 1.58E-02 2.92E-01 semi-lunar valve development (GO:1905314) 27 6 2.67 + 2.25 1.16E-01 9.43E-01 regulation of anion transmembrane transport (GO:1903959) 27 6 2.67 + 2.25 1.16E-01 9.43E-01 positive regulation of receptor signaling pathway via JAK-STAT (GO:0046427) 27 6 2.67 + 2.25 1.16E-01 9.42E-01 regulation of chronic inflammatory response (GO:0002676) 9 2 .89 + 2.25 2.60E-01 1.00E00 regulation of inner ear receptor cell differentiation (GO:2000980) 9 2 .89 + 2.25 2.60E-01 1.00E00 branching involved in prostate gland morphogenesis (GO:0060442) 9 2 .89 + 2.25 2.60E-01 1.00E00 negative regulation of epidermis development (GO:0045683) 9 2 .89 + 2.25 2.60E-01 1.00E00 positive regulation of megakaryocyte differentiation (GO:0045654) 9 2 .89 + 2.25 2.60E-01 1.00E00 regulation of mechanoreceptor differentiation (GO:0045631) 9 2 .89 + 2.25 2.60E-01 1.00E00 regulation of inner ear auditory receptor cell differentiation (GO:0045607) 9 2 .89 + 2.25 2.60E-01 1.00E00 negative regulation of epidermal cell differentiation (GO:0045605) 9 2 .89 + 2.25 2.60E-01 1.00E00 tripartite regional subdivision (GO:0007351) 9 2 .89 + 2.25 2.60E-01 1.00E00 adenosine metabolic process (GO:0046085) 9 2 .89 + 2.25 2.60E-01 1.00E00 regulation of cell adhesion molecule production (GO:0060353) 9 2 .89 + 2.25 2.60E-01 1.00E00 GMP metabolic process (GO:0046037) 9 2 .89 + 2.25 2.60E-01 1.00E00 negative regulation of neuron migration (GO:2001223) 9 2 .89 + 2.25 2.60E-01 1.00E00 trigeminal nerve development (GO:0021559) 9 2 .89 + 2.25 2.60E-01 1.00E00 positive regulation of cytoplasmic translation (GO:2000767) 9 2 .89 + 2.25 2.60E-01 1.00E00 regulation of cytoplasmic translation (GO:2000765) 18 4 1.78 + 2.25 1.30E-01 9.76E-01 metanephric nephron tubule development (GO:0072234) 9 2 .89 + 2.25 2.60E-01 1.00E00 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (GO:1902514) 9 2 .89 + 2.25 2.60E-01 1.00E00 glutathione biosynthetic process (GO:0006750) 9 2 .89 + 2.25 2.60E-01 1.00E00 regulation of CD8-positive, alpha-beta T cell activation (GO:2001185) 18 4 1.78 + 2.25 1.30E-01 9.76E-01 negative regulation of sodium ion transmembrane transporter activity (GO:2000650) 9 2 .89 + 2.25 2.60E-01 1.00E00 phosphatidylethanolamine biosynthetic process (GO:0006646) 9 2 .89 + 2.25 2.60E-01 1.00E00 leukocyte homeostasis (GO:0001776) 90 20 8.90 + 2.25 2.15E-03 6.55E-02 indolalkylamine metabolic process (GO:0006586) 9 2 .89 + 2.25 2.60E-01 1.00E00 tryptophan metabolic process (GO:0006568) 9 2 .89 + 2.25 2.60E-01 1.00E00 negative regulation of interleukin-6 production (GO:0032715) 45 10 4.45 + 2.25 2.90E-02 4.39E-01 regulation of myoblast fusion (GO:1901739) 18 4 1.78 + 2.25 1.30E-01 9.75E-01 positive regulation of neutrophil extravasation (GO:2000391) 9 2 .89 + 2.25 2.60E-01 1.00E00 regulation of immature T cell proliferation in thymus (GO:0033084) 9 2 .89 + 2.25 2.60E-01 1.00E00 negative regulation of fatty acid transport (GO:2000192) 9 2 .89 + 2.25 2.60E-01 1.00E00 regulation of branching morphogenesis of a nerve (GO:2000172) 9 2 .89 + 2.25 2.60E-01 1.00E00 regulation of pigment cell differentiation (GO:0050932) 9 2 .89 + 2.25 2.60E-01 1.00E00 regulation of synaptic transmission, cholinergic (GO:0032222) 9 2 .89 + 2.25 2.60E-01 1.00E00 regulation of protein localization to chromatin (GO:1905634) 9 2 .89 + 2.25 2.60E-01 1.00E00 positive regulation of cell migration involved in sprouting angiogenesis (GO:0090050) 18 4 1.78 + 2.25 1.30E-01 9.75E-01 regulation of B cell receptor signaling pathway (GO:0050855) 18 4 1.78 + 2.25 1.30E-01 9.74E-01 regulation of nucleotide-binding oligomerization domain containing signaling pathway (GO:0070424) 9 2 .89 + 2.25 2.60E-01 1.00E00 regulation of G0 to G1 transition (GO:0070316) 9 2 .89 + 2.25 2.60E-01 1.00E00 postsynaptic specialization assembly (GO:0098698) 9 2 .89 + 2.25 2.60E-01 1.00E00 regulation of protein localization to cell cortex (GO:1904776) 9 2 .89 + 2.25 2.60E-01 1.00E00 anoikis (GO:0043276) 9 2 .89 + 2.25 2.60E-01 1.00E00 auditory behavior (GO:0031223) 9 2 .89 + 2.25 2.60E-01 1.00E00 muscle cell fate commitment (GO:0042693) 9 2 .89 + 2.25 2.60E-01 1.00E00 deoxyribonucleoside metabolic process (GO:0009120) 9 2 .89 + 2.25 2.60E-01 1.00E00 regulation of cytokine production involved in inflammatory response (GO:1900015) 45 10 4.45 + 2.25 2.90E-02 4.38E-01 pharyngeal arch artery morphogenesis (GO:0061626) 9 2 .89 + 2.25 2.60E-01 1.00E00 aromatic amino acid family catabolic process (GO:0009074) 9 2 .89 + 2.25 2.60E-01 1.00E00 anterior/posterior axis specification, embryo (GO:0008595) 9 2 .89 + 2.25 2.60E-01 1.00E00 detection of temperature stimulus (GO:0016048) 18 4 1.78 + 2.25 1.30E-01 9.74E-01 melanocyte differentiation (GO:0030318) 18 4 1.78 + 2.25 1.30E-01 9.73E-01 positive regulation of protein kinase A signaling (GO:0010739) 9 2 .89 + 2.25 2.60E-01 1.00E00 cytoplasmic pattern recognition receptor signaling pathway in response to virus (GO:0039528) 9 2 .89 + 2.25 2.60E-01 1.00E00 coronary artery morphogenesis (GO:0060982) 9 2 .89 + 2.25 2.60E-01 1.00E00 phosphatidylcholine catabolic process (GO:0034638) 9 2 .89 + 2.25 2.60E-01 1.00E00 cardiac neural crest cell development involved in heart development (GO:0061308) 9 2 .89 + 2.25 2.60E-01 1.00E00 establishment of blood-brain barrier (GO:0060856) 9 2 .89 + 2.25 2.60E-01 1.00E00 retina vasculature morphogenesis in camera-type eye (GO:0061299) 9 2 .89 + 2.25 2.60E-01 1.00E00 regulation of mast cell chemotaxis (GO:0060753) 9 2 .89 + 2.25 2.60E-01 1.00E00 physiological cardiac muscle hypertrophy (GO:0003301) 9 2 .89 + 2.25 2.60E-01 1.00E00 regulation of natural killer cell mediated immune response to tumor cell (GO:0002855) 9 2 .89 + 2.25 2.60E-01 1.00E00 positive regulation of fatty acid metabolic process (GO:0045923) 36 8 3.56 + 2.25 5.61E-02 6.52E-01 physiological muscle hypertrophy (GO:0003298) 9 2 .89 + 2.25 2.60E-01 1.00E00 very-low-density lipoprotein particle assembly (GO:0034379) 9 2 .89 + 2.25 2.60E-01 1.00E00 low-density lipoprotein particle remodeling (GO:0034374) 9 2 .89 + 2.25 2.60E-01 1.00E00 negative regulation of glucose import (GO:0046325) 18 4 1.78 + 2.25 1.30E-01 9.73E-01 negative regulation of glial cell apoptotic process (GO:0034351) 9 2 .89 + 2.25 2.60E-01 1.00E00 cellular response to granulocyte macrophage colony-stimulating factor stimulus (GO:0097011) 9 2 .89 + 2.25 2.60E-01 1.00E00 cell growth involved in cardiac muscle cell development (GO:0061049) 9 2 .89 + 2.25 2.60E-01 1.00E00 positive regulation of glycolytic process (GO:0045821) 18 4 1.78 + 2.25 1.30E-01 9.72E-01 aortic valve morphogenesis (GO:0003180) 18 4 1.78 + 2.25 1.30E-01 9.72E-01 negative regulation of immune effector process (GO:0002698) 113 25 11.17 + 2.24 7.74E-04 2.93E-02 alpha-beta T cell activation (GO:0046631) 77 17 7.61 + 2.23 5.46E-03 1.35E-01 regulation of toll-like receptor signaling pathway (GO:0034121) 68 15 6.72 + 2.23 1.03E-02 2.24E-01 negative regulation of protein polymerization (GO:0032272) 68 15 6.72 + 2.23 1.03E-02 2.23E-01 negative regulation of cytokine production (GO:0001818) 241 53 23.83 + 2.22 8.68E-07 8.72E-05 extrinsic apoptotic signaling pathway (GO:0097191) 91 20 9.00 + 2.22 2.33E-03 7.03E-02 negative regulation of leukocyte proliferation (GO:0070664) 82 18 8.11 + 2.22 4.16E-03 1.09E-01 aminoglycan metabolic process (GO:0006022) 82 18 8.11 + 2.22 4.16E-03 1.08E-01 positive regulation of immune effector process (GO:0002699) 228 50 22.54 + 2.22 2.11E-06 1.90E-04 positive regulation of interleukin-2 production (GO:0032743) 32 7 3.16 + 2.21 8.19E-02 8.15E-01 negative regulation of coagulation (GO:0050819) 32 7 3.16 + 2.21 8.19E-02 8.15E-01 lipopolysaccharide-mediated signaling pathway (GO:0031663) 32 7 3.16 + 2.21 8.19E-02 8.14E-01 positive regulation of receptor signaling pathway via STAT (GO:1904894) 32 7 3.16 + 2.21 8.19E-02 8.14E-01 hemostasis (GO:0007599) 96 21 9.49 + 2.21 1.84E-03 5.79E-02 regulation of T cell proliferation (GO:0042129) 160 35 15.82 + 2.21 7.11E-05 3.97E-03 negative regulation of extrinsic apoptotic signaling pathway (GO:2001237) 87 19 8.60 + 2.21 3.23E-03 9.07E-02 cytokine-mediated signaling pathway (GO:0019221) 229 50 22.64 + 2.21 2.25E-06 2.00E-04 toll-like receptor signaling pathway (GO:0002224) 55 12 5.44 + 2.21 1.73E-02 3.14E-01 regulation of leukocyte cell-cell adhesion (GO:1903037) 289 63 28.57 + 2.20 1.30E-07 1.68E-05 B cell activation (GO:0042113) 156 34 15.42 + 2.20 9.78E-05 5.08E-03 leukocyte activation (GO:0045321) 496 108 49.04 + 2.20 2.46E-12 5.84E-10 negative regulation of hydrogen peroxide-induced cell death (GO:1903206) 23 5 2.27 + 2.20 1.02E-01 8.80E-01 response to zinc ion (GO:0010043) 23 5 2.27 + 2.20 1.02E-01 8.80E-01 B cell activation involved in immune response (GO:0002312) 46 10 4.55 + 2.20 3.14E-02 4.63E-01 regulation of dopamine secretion (GO:0014059) 23 5 2.27 + 2.20 1.02E-01 8.79E-01 modulation by symbiont of host process (GO:0044003) 23 5 2.27 + 2.20 1.02E-01 8.79E-01 negative regulation of response to reactive oxygen species (GO:1901032) 23 5 2.27 + 2.20 1.02E-01 8.78E-01 cellular response to acetylcholine (GO:1905145) 23 5 2.27 + 2.20 1.02E-01 8.78E-01 response to acetylcholine (GO:1905144) 23 5 2.27 + 2.20 1.02E-01 8.77E-01 positive regulation of vascular endothelial growth factor production (GO:0010575) 23 5 2.27 + 2.20 1.02E-01 8.77E-01 regulation of cytokine production (GO:0001817) 640 139 63.28 + 2.20 1.57E-15 6.44E-13 negative regulation of cell-cell adhesion (GO:0022408) 175 38 17.30 + 2.20 4.96E-05 2.94E-03 phenol-containing compound metabolic process (GO:0018958) 60 13 5.93 + 2.19 2.09E-02 3.54E-01 positive regulation of interleukin-1 production (GO:0032732) 60 13 5.93 + 2.19 2.09E-02 3.53E-01 integrin-mediated signaling pathway (GO:0007229) 74 16 7.32 + 2.19 8.15E-03 1.86E-01 regulation of blood coagulation (GO:0030193) 51 11 5.04 + 2.18 2.42E-02 3.88E-01 positive regulation of leukocyte cell-cell adhesion (GO:1903039) 209 45 20.66 + 2.18 1.12E-05 8.34E-04 regulation of defense response (GO:0031347) 499 107 49.34 + 2.17 7.57E-12 1.62E-09 regulation of viral genome replication (GO:0045069) 70 15 6.92 + 2.17 1.14E-02 2.40E-01 negative regulation of cellular carbohydrate metabolic process (GO:0010677) 42 9 4.15 + 2.17 4.46E-02 5.59E-01 response to UV-B (GO:0010224) 14 3 1.38 + 2.17 1.93E-01 1.00E00 heterotypic cell-cell adhesion (GO:0034113) 28 6 2.77 + 2.17 1.20E-01 9.72E-01 negative regulation of anoikis (GO:2000811) 14 3 1.38 + 2.17 1.93E-01 1.00E00 positive regulation of regulatory T cell differentiation (GO:0045591) 14 3 1.38 + 2.17 1.93E-01 1.00E00 immature B cell differentiation (GO:0002327) 14 3 1.38 + 2.17 1.93E-01 1.00E00 myeloid dendritic cell activation (GO:0001773) 28 6 2.77 + 2.17 1.20E-01 9.71E-01 regulation of cell proliferation involved in kidney development (GO:1901722) 14 3 1.38 + 2.17 1.93E-01 1.00E00 ganglioside biosynthetic process (GO:0001574) 14 3 1.38 + 2.17 1.93E-01 1.00E00 negative regulation of calcineurin-NFAT signaling cascade (GO:0070885) 14 3 1.38 + 2.17 1.93E-01 1.00E00 negative regulation of multicellular organism growth (GO:0040015) 14 3 1.38 + 2.17 1.93E-01 1.00E00 purine nucleobase metabolic process (GO:0006144) 14 3 1.38 + 2.17 1.93E-01 1.00E00 regulation of keratinocyte migration (GO:0051547) 14 3 1.38 + 2.17 1.93E-01 1.00E00 negative regulation of oligodendrocyte differentiation (GO:0048715) 14 3 1.38 + 2.17 1.93E-01 1.00E00 positive regulation of prostaglandin secretion (GO:0032308) 14 3 1.38 + 2.17 1.93E-01 1.00E00 negative regulation of calcineurin-mediated signaling (GO:0106057) 14 3 1.38 + 2.17 1.93E-01 1.00E00 regulation of neurotrophin TRK receptor signaling pathway (GO:0051386) 14 3 1.38 + 2.17 1.93E-01 1.00E00 embryonic digestive tract morphogenesis (GO:0048557) 14 3 1.38 + 2.17 1.93E-01 1.00E00 lymph node development (GO:0048535) 28 6 2.77 + 2.17 1.20E-01 9.71E-01 regulation of relaxation of muscle (GO:1901077) 14 3 1.38 + 2.17 1.93E-01 1.00E00 dendritic cell migration (GO:0036336) 14 3 1.38 + 2.17 1.93E-01 1.00E00 xenobiotic transport (GO:0042908) 28 6 2.77 + 2.17 1.20E-01 9.70E-01 regulation of long-term synaptic depression (GO:1900452) 14 3 1.38 + 2.17 1.93E-01 1.00E00 erythrocyte maturation (GO:0043249) 14 3 1.38 + 2.17 1.93E-01 1.00E00 amine catabolic process (GO:0009310) 14 3 1.38 + 2.17 1.93E-01 1.00E00 regulation of inositol phosphate biosynthetic process (GO:0010919) 14 3 1.38 + 2.17 1.93E-01 1.00E00 thyroid hormone metabolic process (GO:0042403) 14 3 1.38 + 2.17 1.93E-01 1.00E00 cellular biogenic amine catabolic process (GO:0042402) 14 3 1.38 + 2.17 1.93E-01 1.00E00 magnesium ion transport (GO:0015693) 14 3 1.38 + 2.17 1.93E-01 1.00E00 cytolysis (GO:0019835) 14 3 1.38 + 2.17 1.93E-01 1.00E00 regulation of vascular endothelial growth factor production (GO:0010574) 28 6 2.77 + 2.17 1.20E-01 9.70E-01 negative regulation of humoral immune response (GO:0002921) 14 3 1.38 + 2.17 1.93E-01 1.00E00 negative regulation of ATP metabolic process (GO:1903579) 28 6 2.77 + 2.17 1.20E-01 9.69E-01 protein refolding (GO:0042026) 14 3 1.38 + 2.17 1.93E-01 1.00E00 positive regulation of synaptic vesicle recycling (GO:1903423) 14 3 1.38 + 2.17 1.93E-01 1.00E00 regulation of dendritic cell cytokine production (GO:0002730) 14 3 1.38 + 2.17 1.93E-01 1.00E00 negative regulation of response to oxidative stress (GO:1902883) 28 6 2.77 + 2.17 1.20E-01 9.69E-01 endocytosis (GO:0006897) 383 82 37.87 + 2.17 2.81E-09 4.64E-07 positive regulation of gliogenesis (GO:0014015) 61 13 6.03 + 2.16 2.17E-02 3.64E-01 negative regulation of transmembrane transport (GO:0034763) 108 23 10.68 + 2.15 1.79E-03 5.64E-02 positive regulation of tyrosine phosphorylation of STAT protein (GO:0042531) 47 10 4.65 + 2.15 3.40E-02 4.89E-01 negative regulation of carbohydrate metabolic process (GO:0045912) 47 10 4.65 + 2.15 3.40E-02 4.89E-01 lymphocyte activation (GO:0046649) 400 85 39.55 + 2.15 2.18E-09 3.76E-07 negative regulation of immune system process (GO:0002683) 391 83 38.66 + 2.15 2.65E-09 4.41E-07 positive regulation of leukocyte differentiation (GO:1902107) 165 35 16.31 + 2.15 1.44E-04 7.02E-03 positive T cell selection (GO:0043368) 33 7 3.26 + 2.15 8.65E-02 8.23E-01 positive regulation of hemopoiesis (GO:1903708) 165 35 16.31 + 2.15 1.44E-04 7.00E-03 negative regulation of ossification (GO:0030279) 33 7 3.26 + 2.15 8.65E-02 8.22E-01 negative regulation of T cell proliferation (GO:0042130) 66 14 6.53 + 2.15 1.61E-02 2.98E-01 positive regulation of ATP metabolic process (GO:1903580) 33 7 3.26 + 2.15 8.65E-02 8.22E-01 homeostasis of number of cells (GO:0048872) 274 58 27.09 + 2.14 8.39E-07 8.54E-05 unsaturated fatty acid metabolic process (GO:0033559) 52 11 5.14 + 2.14 2.64E-02 4.17E-01 regulation of granulocyte chemotaxis (GO:0071622) 52 11 5.14 + 2.14 2.64E-02 4.17E-01 cellular response to carbohydrate stimulus (GO:0071322) 52 11 5.14 + 2.14 2.64E-02 4.16E-01 regulation of hemostasis (GO:1900046) 52 11 5.14 + 2.14 2.64E-02 4.16E-01 positive regulation of defense response (GO:0031349) 227 48 22.44 + 2.14 9.17E-06 7.14E-04 cell activation (GO:0001775) 564 119 55.76 + 2.13 1.36E-12 3.56E-10 regulation of hepatocyte proliferation (GO:2000345) 19 4 1.88 + 2.13 1.47E-01 1.00E00 positive regulation of calcium ion import (GO:0090280) 19 4 1.88 + 2.13 1.47E-01 1.00E00 negative regulation of calcium-mediated signaling (GO:0050849) 19 4 1.88 + 2.13 1.47E-01 1.00E00 regulation of p38MAPK cascade (GO:1900744) 38 8 3.76 + 2.13 6.38E-02 7.10E-01 positive regulation of nervous system process (GO:0031646) 38 8 3.76 + 2.13 6.38E-02 7.10E-01 positive regulation of lymphocyte apoptotic process (GO:0070230) 19 4 1.88 + 2.13 1.47E-01 1.00E00 barbed-end actin filament capping (GO:0051016) 19 4 1.88 + 2.13 1.47E-01 1.00E00 regulation of receptor binding (GO:1900120) 19 4 1.88 + 2.13 1.47E-01 1.00E00 chloride ion homeostasis (GO:0055064) 19 4 1.88 + 2.13 1.47E-01 1.00E00 embryonic forelimb morphogenesis (GO:0035115) 19 4 1.88 + 2.13 1.47E-01 1.00E00 regulation of reactive oxygen species biosynthetic process (GO:1903426) 38 8 3.76 + 2.13 6.38E-02 7.09E-01 regulation of interleukin-2 production (GO:0032663) 57 12 5.64 + 2.13 3.09E-02 4.56E-01 positive regulation of cytokine production involved in immune response (GO:0002720) 57 12 5.64 + 2.13 3.09E-02 4.56E-01 leukocyte differentiation (GO:0002521) 352 74 34.80 + 2.13 3.87E-08 5.33E-06 regulation of lymphocyte apoptotic process (GO:0070228) 62 13 6.13 + 2.12 2.27E-02 3.76E-01 B cell differentiation (GO:0030183) 105 22 10.38 + 2.12 2.63E-03 7.70E-02 calcium-mediated signaling (GO:0019722) 105 22 10.38 + 2.12 2.63E-03 7.69E-02 negative regulation of peptidase activity (GO:0010466) 148 31 14.63 + 2.12 3.37E-04 1.46E-02 glomerulus development (GO:0032835) 43 9 4.25 + 2.12 4.81E-02 5.93E-01 negative regulation of cellular response to insulin stimulus (GO:1900077) 43 9 4.25 + 2.12 4.81E-02 5.93E-01 biological process involved in symbiotic interaction (GO:0044403) 153 32 15.13 + 2.12 3.81E-04 1.62E-02 regulation of immune effector process (GO:0002697) 335 70 33.12 + 2.11 8.62E-08 1.15E-05 mononuclear cell differentiation (GO:1903131) 292 61 28.87 + 2.11 6.68E-07 6.99E-05 positive regulation of T cell activation (GO:0050870) 187 39 18.49 + 2.11 8.45E-05 4.48E-03 positive regulation of interleukin-4 production (GO:0032753) 24 5 2.37 + 2.11 1.79E-01 9.98E-01 regulation of glycogen biosynthetic process (GO:0005979) 24 5 2.37 + 2.11 1.79E-01 9.97E-01 regulation of T cell differentiation in thymus (GO:0033081) 24 5 2.37 + 2.11 1.79E-01 9.97E-01 regulation of mast cell activation (GO:0033003) 48 10 4.75 + 2.11 3.70E-02 5.15E-01 phagosome maturation (GO:0090382) 24 5 2.37 + 2.11 1.79E-01 9.97E-01 detection of mechanical stimulus (GO:0050982) 48 10 4.75 + 2.11 3.70E-02 5.15E-01 regulation of glucan biosynthetic process (GO:0010962) 24 5 2.37 + 2.11 1.79E-01 9.96E-01 acylglycerol biosynthetic process (GO:0046463) 24 5 2.37 + 2.11 1.79E-01 9.96E-01 neutral lipid biosynthetic process (GO:0046460) 24 5 2.37 + 2.11 1.79E-01 9.96E-01 regulation of smooth muscle cell apoptotic process (GO:0034391) 24 5 2.37 + 2.11 1.79E-01 9.95E-01 negative regulation of regulated secretory pathway (GO:1903306) 24 5 2.37 + 2.11 1.79E-01 9.95E-01 modulation of process of other organism involved in symbiotic interaction (GO:0051817) 77 16 7.61 + 2.10 1.00E-02 2.19E-01 regulation of carbohydrate catabolic process (GO:0043470) 53 11 5.24 + 2.10 4.39E-02 5.52E-01 positive regulation of cell-cell adhesion (GO:0022409) 246 51 24.32 + 2.10 7.66E-06 6.15E-04 regulation of reactive oxygen species metabolic process (GO:2000377) 140 29 13.84 + 2.10 6.28E-04 2.51E-02 regulation of interleukin-4 production (GO:0032673) 29 6 2.87 + 2.09 1.26E-01 9.53E-01 hemopoiesis (GO:0030097) 600 124 59.32 + 2.09 1.37E-12 3.53E-10 regulation of T-helper cell differentiation (GO:0045622) 34 7 3.36 + 2.08 9.19E-02 8.55E-01 activation of innate immune response (GO:0002218) 34 7 3.36 + 2.08 9.19E-02 8.54E-01 negative regulation of protein localization to nucleus (GO:1900181) 34 7 3.36 + 2.08 9.19E-02 8.54E-01 long-term memory (GO:0007616) 34 7 3.36 + 2.08 9.19E-02 8.53E-01 positive regulation of lymphocyte differentiation (GO:0045621) 107 22 10.58 + 2.08 3.01E-03 8.54E-02 regulation of amino acid transport (GO:0051955) 39 8 3.86 + 2.07 6.84E-02 7.23E-01 cellular response to vascular endothelial growth factor stimulus (GO:0035924) 39 8 3.86 + 2.07 6.84E-02 7.22E-01 negative regulation of viral process (GO:0048525) 83 17 8.21 + 2.07 1.23E-02 2.52E-01 negative regulation of T cell differentiation (GO:0045581) 44 9 4.35 + 2.07 5.20E-02 6.23E-01 positive regulation of pattern recognition receptor signaling pathway (GO:0062208) 44 9 4.35 + 2.07 5.20E-02 6.23E-01 regulation of viral entry into host cell (GO:0046596) 44 9 4.35 + 2.07 5.20E-02 6.22E-01 positive regulation of response to external stimulus (GO:0032103) 357 73 35.30 + 2.07 1.22E-07 1.60E-05 regulation of myeloid cell differentiation (GO:0045637) 187 38 18.49 + 2.06 1.41E-04 6.90E-03 T cell activation (GO:0042110) 251 51 24.82 + 2.06 9.94E-06 7.62E-04 regulation of angiogenesis (GO:0045765) 256 52 25.31 + 2.05 1.14E-05 8.44E-04 regulation of cold-induced thermogenesis (GO:0120161) 128 26 12.66 + 2.05 1.60E-03 5.23E-02 negative regulation of leukocyte differentiation (GO:1902106) 94 19 9.29 + 2.04 7.33E-03 1.71E-01 cell-matrix adhesion (GO:0007160) 99 20 9.79 + 2.04 5.66E-03 1.40E-01 regulation of chemotaxis (GO:0050920) 198 40 19.58 + 2.04 1.30E-04 6.43E-03 negative regulation of ion transport (GO:0043271) 129 26 12.75 + 2.04 1.70E-03 5.45E-02 positive regulation of peptidyl-tyrosine phosphorylation (GO:0050731) 164 33 16.21 + 2.04 5.90E-04 2.38E-02 hematopoietic or lymphoid organ development (GO:0048534) 647 130 63.97 + 2.03 1.99E-12 4.79E-10 response to metal ion (GO:0010038) 224 45 22.15 + 2.03 5.43E-05 3.16E-03 negative regulation of cell adhesion (GO:0007162) 254 51 25.11 + 2.03 1.66E-05 1.12E-03 lymphocyte differentiation (GO:0030098) 259 52 25.61 + 2.03 1.27E-05 9.15E-04 negative regulation of acute inflammatory response (GO:0002674) 10 2 .99 + 2.02 2.95E-01 1.00E00 regulation of T cell tolerance induction (GO:0002664) 10 2 .99 + 2.02 2.95E-01 1.00E00 negative regulation of cell volume (GO:0045794) 5 1 .49 + 2.02 4.32E-01 1.00E00 branchiomotor neuron axon guidance (GO:0021785) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of glycogen biosynthetic process (GO:0045719) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of protein targeting to mitochondrion (GO:1903215) 5 1 .49 + 2.02 4.32E-01 1.00E00 renal sodium ion transport (GO:0003096) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of oxidative stress-induced cell death (GO:1903209) 20 4 1.98 + 2.02 2.68E-01 1.00E00 regulation of the force of heart contraction by chemical signal (GO:0003057) 5 1 .49 + 2.02 4.32E-01 1.00E00 response to DNA damage checkpoint signaling (GO:0072423) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of cardiac muscle contraction (GO:0060452) 5 1 .49 + 2.02 4.32E-01 1.00E00 late endosome to lysosome transport (GO:1902774) 5 1 .49 + 2.02 4.32E-01 1.00E00 response to DNA integrity checkpoint signaling (GO:0072402) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of lens fiber cell differentiation (GO:1902747) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of proteoglycan biosynthetic process (GO:1902730) 5 1 .49 + 2.02 4.32E-01 1.00E00 inosine metabolic process (GO:0046102) 5 1 .49 + 2.02 4.32E-01 1.00E00 toll-like receptor 3 signaling pathway (GO:0034138) 10 2 .99 + 2.02 2.95E-01 1.00E00 somatic diversification of T cell receptor genes (GO:0002568) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of cohesin loading (GO:0071922) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of melanocyte differentiation (GO:0045636) 5 1 .49 + 2.02 4.32E-01 1.00E00 lipoxygenase pathway (GO:0019372) 10 2 .99 + 2.02 2.95E-01 1.00E00 transsulfuration (GO:0019346) 5 1 .49 + 2.02 4.32E-01 1.00E00 response to cell cycle checkpoint signaling (GO:0072396) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of dopamine secretion (GO:0033603) 5 1 .49 + 2.02 4.32E-01 1.00E00 minus-end-directed organelle transport along microtubule (GO:0072385) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of growth hormone receptor signaling pathway (GO:0060398) 5 1 .49 + 2.02 4.32E-01 1.00E00 cranial nerve formation (GO:0021603) 5 1 .49 + 2.02 4.32E-01 1.00E00 pathway-restricted SMAD protein phosphorylation (GO:0060389) 10 2 .99 + 2.02 2.95E-01 1.00E00 axonogenesis involved in innervation (GO:0060385) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of mast cell differentiation (GO:0060375) 5 1 .49 + 2.02 4.32E-01 1.00E00 cranial suture morphogenesis (GO:0060363) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of corticosteroid hormone secretion (GO:2000846) 10 2 .99 + 2.02 2.95E-01 1.00E00 type I interferon signaling pathway (GO:0060337) 15 3 1.48 + 2.02 2.17E-01 1.00E00 negative regulation of interferon-gamma-mediated signaling pathway (GO:0060336) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of response to interferon-gamma (GO:0060331) 5 1 .49 + 2.02 4.32E-01 1.00E00 protein localization to adherens junction (GO:0071896) 5 1 .49 + 2.02 4.32E-01 1.00E00 manganese ion transport (GO:0006828) 15 3 1.48 + 2.02 2.17E-01 1.00E00 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (GO:2001269) 10 2 .99 + 2.02 2.95E-01 1.00E00 spermatogonial cell division (GO:0007284) 5 1 .49 + 2.02 4.32E-01 1.00E00 spinal cord motor neuron cell fate specification (GO:0021520) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of respiratory burst involved in inflammatory response (GO:0060264) 5 1 .49 + 2.02 4.32E-01 1.00E00 metanephric epithelium development (GO:0072207) 15 3 1.48 + 2.02 2.17E-01 1.00E00 NADP catabolic process (GO:0006742) 5 1 .49 + 2.02 4.32E-01 1.00E00 T cell lineage commitment (GO:0002360) 25 5 2.47 + 2.02 1.86E-01 1.00E00 cellular response to nitric oxide (GO:0071732) 10 2 .99 + 2.02 2.95E-01 1.00E00 steroid catabolic process (GO:0006706) 15 3 1.48 + 2.02 2.17E-01 1.00E00 negative regulation of CD8-positive, alpha-beta T cell activation (GO:2001186) 5 1 .49 + 2.02 4.32E-01 1.00E00 leukotriene transport (GO:0071716) 5 1 .49 + 2.02 4.32E-01 1.00E00 pro-B cell differentiation (GO:0002328) 5 1 .49 + 2.02 4.32E-01 1.00E00 neuron cell-cell adhesion (GO:0007158) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of epithelial cell differentiation involved in kidney development (GO:2000696) 10 2 .99 + 2.02 2.95E-01 1.00E00 inner cell mass cell differentiation (GO:0001826) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of protein autoubiquitination (GO:1902498) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of glomerular mesangial cell proliferation (GO:0072124) 10 2 .99 + 2.02 2.95E-01 1.00E00 inositol trisphosphate metabolic process (GO:0032957) 10 2 .99 + 2.02 2.95E-01 1.00E00 prepulse inhibition (GO:0060134) 10 2 .99 + 2.02 2.95E-01 1.00E00 inner ear receptor cell fate commitment (GO:0060120) 5 1 .49 + 2.02 4.32E-01 1.00E00 ganglioside catabolic process (GO:0006689) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of transforming growth factor beta1 production (GO:0032911) 5 1 .49 + 2.02 4.32E-01 1.00E00 protein processing involved in protein targeting to mitochondrion (GO:0006627) 5 1 .49 + 2.02 4.32E-01 1.00E00 xenobiotic transport across blood-brain barrier (GO:1990962) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of response to drug (GO:2001023) 5 1 .49 + 2.02 4.32E-01 1.00E00 DNA repair complex assembly (GO:0090735) 5 1 .49 + 2.02 4.32E-01 1.00E00 loop of Henle development (GO:0072070) 5 1 .49 + 2.02 4.32E-01 1.00E00 S-shaped body morphogenesis (GO:0072050) 5 1 .49 + 2.02 4.32E-01 1.00E00 post-chaperonin tubulin folding pathway (GO:0007023) 5 1 .49 + 2.02 4.32E-01 1.00E00 cannabinoid signaling pathway (GO:0038171) 5 1 .49 + 2.02 4.32E-01 1.00E00 proximal tubule development (GO:0072014) 5 1 .49 + 2.02 4.32E-01 1.00E00 anatomical structure regression (GO:0060033) 10 2 .99 + 2.02 2.95E-01 1.00E00 chemokine (C-X-C motif) ligand 12 signaling pathway (GO:0038146) 5 1 .49 + 2.02 4.32E-01 1.00E00 soft palate development (GO:0060023) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of sodium ion transmembrane transport (GO:1902306) 10 2 .99 + 2.02 2.95E-01 1.00E00 histidine metabolic process (GO:0006547) 5 1 .49 + 2.02 4.32E-01 1.00E00 glutamate catabolic process (GO:0006538) 5 1 .49 + 2.02 4.32E-01 1.00E00 response to heparin (GO:0071503) 5 1 .49 + 2.02 4.32E-01 1.00E00 leptin-mediated signaling pathway (GO:0033210) 10 2 .99 + 2.02 2.95E-01 1.00E00 negative regulation by host of viral process (GO:0044793) 10 2 .99 + 2.02 2.95E-01 1.00E00 positive regulation by host of viral release from host cell (GO:0044791) 5 1 .49 + 2.02 4.32E-01 1.00E00 modulation by host of viral release from host cell (GO:0044789) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of protein neddylation (GO:2000436) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of protein neddylation (GO:2000434) 10 2 .99 + 2.02 2.95E-01 1.00E00 positive regulation of interleukin-18 production (GO:0032741) 5 1 .49 + 2.02 4.32E-01 1.00E00 paracrine signaling (GO:0038001) 5 1 .49 + 2.02 4.32E-01 1.00E00 dorsal root ganglion development (GO:1990791) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of neuron maturation (GO:0014042) 5 1 .49 + 2.02 4.32E-01 1.00E00 cellular response to hyperoxia (GO:0071455) 5 1 .49 + 2.02 4.32E-01 1.00E00 columnar/cuboidal epithelial cell maturation (GO:0002069) 5 1 .49 + 2.02 4.32E-01 1.00E00 manganese ion transmembrane transport (GO:0071421) 5 1 .49 + 2.02 4.32E-01 1.00E00 oligodendrocyte development (GO:0014003) 35 7 3.46 + 2.02 9.79E-02 8.62E-01 cellular response to purine-containing compound (GO:0071415) 10 2 .99 + 2.02 2.95E-01 1.00E00 positive regulation of myoblast fusion (GO:1901741) 15 3 1.48 + 2.02 2.17E-01 1.00E00 T cell receptor V(D)J recombination (GO:0033153) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of histone deacetylase activity (GO:1901727) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of glucokinase activity (GO:0033133) 5 1 .49 + 2.02 4.32E-01 1.00E00 branching involved in blood vessel morphogenesis (GO:0001569) 35 7 3.46 + 2.02 9.79E-02 8.61E-01 sphingolipid mediated signaling pathway (GO:0090520) 10 2 .99 + 2.02 2.95E-01 1.00E00 endocardial cushion to mesenchymal transition (GO:0090500) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of chemokine production (GO:0032682) 20 4 1.98 + 2.02 2.68E-01 1.00E00 negative regulation of endothelial cell apoptotic process (GO:2000352) 25 5 2.47 + 2.02 1.86E-01 1.00E00 regulation of interleukin-5 production (GO:0032674) 15 3 1.48 + 2.02 2.17E-01 1.00E00 positive regulation of ceramide biosynthetic process (GO:2000304) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of ceramide biosynthetic process (GO:2000303) 10 2 .99 + 2.02 2.95E-01 1.00E00 cellular response to fatty acid (GO:0071398) 15 3 1.48 + 2.02 2.17E-01 1.00E00 cellular response to glucocorticoid stimulus (GO:0071385) 30 6 2.97 + 2.02 1.33E-01 9.90E-01 cellular response to type I interferon (GO:0071357) 15 3 1.48 + 2.02 2.17E-01 1.00E00 cellular response to interleukin-4 (GO:0071353) 25 5 2.47 + 2.02 1.86E-01 1.00E00 positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) 20 4 1.98 + 2.02 2.68E-01 1.00E00 iron coordination entity transport (GO:1901678) 10 2 .99 + 2.02 2.95E-01 1.00E00 positive regulation of immature T cell proliferation (GO:0033091) 5 1 .49 + 2.02 4.32E-01 1.00E00 protein retention in Golgi apparatus (GO:0045053) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of T cell differentiation in thymus (GO:0033089) 10 2 .99 + 2.02 2.95E-01 1.00E00 positive regulation of mast cell activation involved in immune response (GO:0033008) 20 4 1.98 + 2.02 2.68E-01 1.00E00 modulation by symbiont of host apoptotic process (GO:0052150) 5 1 .49 + 2.02 4.32E-01 1.00E00 dipeptide import across plasma membrane (GO:0140206) 5 1 .49 + 2.02 4.32E-01 1.00E00 oligopeptide import across plasma membrane (GO:0140205) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of mitochondrial RNA catabolic process (GO:0000960) 5 1 .49 + 2.02 4.32E-01 1.00E00 cellular response to calcium ion (GO:0071277) 60 12 5.93 + 2.02 3.53E-02 4.99E-01 positive regulation of gonad development (GO:1905941) 5 1 .49 + 2.02 4.32E-01 1.00E00 endoplasmic reticulum localization (GO:0051643) 10 2 .99 + 2.02 2.95E-01 1.00E00 regulation of gonad development (GO:1905939) 10 2 .99 + 2.02 2.95E-01 1.00E00 regulation of serotonin uptake (GO:0051611) 5 1 .49 + 2.02 4.32E-01 1.00E00 exocyst localization (GO:0051601) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of platelet aggregation (GO:0090330) 20 4 1.98 + 2.02 2.68E-01 1.00E00 leukemia inhibitory factor signaling pathway (GO:0048861) 5 1 .49 + 2.02 4.32E-01 1.00E00 hair follicle maturation (GO:0048820) 15 3 1.48 + 2.02 2.17E-01 1.00E00 regulation of Cdc42 protein signal transduction (GO:0032489) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of protein oligomerization (GO:0032459) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of development, heterochronic (GO:0040034) 10 2 .99 + 2.02 2.95E-01 1.00E00 oxaloacetate metabolic process (GO:0006107) 10 2 .99 + 2.02 2.95E-01 1.00E00 negative regulation of calcium ion import (GO:0090281) 10 2 .99 + 2.02 2.95E-01 1.00E00 positive regulation of fibroblast growth factor production (GO:0090271) 5 1 .49 + 2.02 4.32E-01 1.00E00 animal organ maturation (GO:0048799) 20 4 1.98 + 2.02 2.68E-01 1.00E00 regulation of tetrapyrrole metabolic process (GO:1901401) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of triglyceride metabolic process (GO:0090209) 10 2 .99 + 2.02 2.95E-01 1.00E00 type B pancreatic cell proliferation (GO:0044342) 10 2 .99 + 2.02 2.95E-01 1.00E00 regulation of cell-cell adhesion mediated by cadherin (GO:2000047) 15 3 1.48 + 2.02 2.17E-01 1.00E00 regulation of determination of dorsal identity (GO:2000015) 5 1 .49 + 2.02 4.32E-01 1.00E00 alanine transport (GO:0032328) 10 2 .99 + 2.02 2.95E-01 1.00E00 negative regulation of phospholipid biosynthetic process (GO:0071072) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of filopodium assembly (GO:0051489) 45 9 4.45 + 2.02 5.63E-02 6.54E-01 DNA recombinase assembly (GO:0000730) 5 1 .49 + 2.02 4.32E-01 1.00E00 fructose 2,6-bisphosphate metabolic process (GO:0006003) 5 1 .49 + 2.02 4.32E-01 1.00E00 cellular water homeostasis (GO:0009992) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of branching involved in ureteric bud morphogenesis (GO:0090190) 15 3 1.48 + 2.02 2.17E-01 1.00E00 regulation of vasculature development (GO:1901342) 260 52 25.71 + 2.02 1.33E-05 9.49E-04 negative regulation of pancreatic juice secretion (GO:0090188) 5 1 .49 + 2.02 4.32E-01 1.00E00 auditory receptor cell fate commitment (GO:0009912) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of sphingolipid biosynthetic process (GO:0090154) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of lipid catabolic process (GO:0050996) 20 4 1.98 + 2.02 2.68E-01 1.00E00 detection of mechanical stimulus involved in sensory perception (GO:0050974) 35 7 3.46 + 2.02 9.79E-02 8.61E-01 regulation of synapse maturation (GO:0090128) 15 3 1.48 + 2.02 2.17E-01 1.00E00 central nervous system myelin formation (GO:0032289) 5 1 .49 + 2.02 4.32E-01 1.00E00 sensory perception of bitter taste (GO:0050913) 10 2 .99 + 2.02 2.95E-01 1.00E00 activation of store-operated calcium channel activity (GO:0032237) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of synaptic transmission, GABAergic (GO:0032229) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway (GO:0070428) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway (GO:0070426) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of acyl-CoA biosynthetic process (GO:0050812) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of sequestering of calcium ion (GO:0051284) 10 2 .99 + 2.02 2.95E-01 1.00E00 negative regulation of release of sequestered calcium ion into cytosol (GO:0051280) 10 2 .99 + 2.02 2.95E-01 1.00E00 recognition of apoptotic cell (GO:0043654) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of mitotic cell cycle, embryonic (GO:0009794) 5 1 .49 + 2.02 4.32E-01 1.00E00 astrocyte cell migration (GO:0043615) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of G0 to G1 transition (GO:0070317) 5 1 .49 + 2.02 4.32E-01 1.00E00 maintenance of lens transparency (GO:0036438) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of nuclease activity (GO:0032069) 25 5 2.47 + 2.02 1.86E-01 1.00E00 DNA hypermethylation (GO:0044026) 5 1 .49 + 2.02 4.32E-01 1.00E00 hemidesmosome assembly (GO:0031581) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of lymphoid progenitor cell differentiation (GO:1905456) 10 2 .99 + 2.02 2.95E-01 1.00E00 positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis (GO:1905451) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of blood vessel endothelial cell migration (GO:0043536) 50 10 4.94 + 2.02 6.44E-02 7.13E-01 ascending aorta development (GO:0035905) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of exit from mitosis (GO:0031536) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of thymocyte apoptotic process (GO:0070243) 15 3 1.48 + 2.02 2.17E-01 1.00E00 negative regulation of activation-induced cell death of T cells (GO:0070236) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of T cell apoptotic process (GO:0070232) 40 8 3.95 + 2.02 7.36E-02 7.49E-01 paraxial mesoderm formation (GO:0048341) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of macrophage proliferation (GO:0120041) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of macrophage proliferation (GO:0120040) 5 1 .49 + 2.02 4.32E-01 1.00E00 calmodulin dependent kinase signaling pathway (GO:0099004) 5 1 .49 + 2.02 4.32E-01 1.00E00 plasma membrane lactate transport (GO:0035879) 5 1 .49 + 2.02 4.32E-01 1.00E00 imitative learning (GO:0098596) 5 1 .49 + 2.02 4.32E-01 1.00E00 lactate transmembrane transport (GO:0035873) 5 1 .49 + 2.02 4.32E-01 1.00E00 detection of chemical stimulus (GO:0009593) 35 7 3.46 + 2.02 9.79E-02 8.60E-01 negative regulation of membrane protein ectodomain proteolysis (GO:0051045) 5 1 .49 + 2.02 4.32E-01 1.00E00 rRNA transport (GO:0051029) 5 1 .49 + 2.02 4.32E-01 1.00E00 actin filament severing (GO:0051014) 15 3 1.48 + 2.02 2.17E-01 1.00E00 dipeptide transport (GO:0042938) 5 1 .49 + 2.02 4.32E-01 1.00E00 establishment or maintenance of actin cytoskeleton polarity (GO:0030950) 5 1 .49 + 2.02 4.32E-01 1.00E00 9-cis-retinoic acid metabolic process (GO:0042905) 5 1 .49 + 2.02 4.32E-01 1.00E00 9-cis-retinoic acid biosynthetic process (GO:0042904) 5 1 .49 + 2.02 4.32E-01 1.00E00 CD8-positive, alpha-beta T cell differentiation (GO:0043374) 10 2 .99 + 2.02 2.95E-01 1.00E00 regulation of retrograde transport, endosome to Golgi (GO:1905279) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of mast cell degranulation (GO:0043306) 20 4 1.98 + 2.02 2.68E-01 1.00E00 negative regulation of mast cell degranulation (GO:0043305) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of vesicle fusion (GO:0031339) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of viral transcription (GO:0050434) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of potassium ion transport (GO:0043267) 30 6 2.97 + 2.02 1.33E-01 9.90E-01 sodium-independent organic anion transport (GO:0043252) 10 2 .99 + 2.02 2.95E-01 1.00E00 negative regulation of cyclase activity (GO:0031280) 10 2 .99 + 2.02 2.95E-01 1.00E00 stress granule disassembly (GO:0035617) 5 1 .49 + 2.02 4.32E-01 1.00E00 amine metabolic process (GO:0009308) 70 14 6.92 + 2.02 2.06E-02 3.52E-01 regulation of NLRP3 inflammasome complex assembly (GO:1900225) 15 3 1.48 + 2.02 2.17E-01 1.00E00 regulation of SNARE complex assembly (GO:0035542) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of metallopeptidase activity (GO:1905049) 5 1 .49 + 2.02 4.32E-01 1.00E00 carboxylic acid transmembrane transport (GO:1905039) 95 19 9.39 + 2.02 7.77E-03 1.79E-01 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation (GO:1905007) 5 1 .49 + 2.02 4.32E-01 1.00E00 fatty acid transport (GO:0015908) 40 8 3.95 + 2.02 7.36E-02 7.48E-01 thelarche (GO:0042695) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of lipophagy (GO:1904504) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of lipophagy (GO:1904502) 5 1 .49 + 2.02 4.32E-01 1.00E00 monovalent inorganic anion homeostasis (GO:0055083) 20 4 1.98 + 2.02 2.68E-01 1.00E00 drug transport (GO:0015893) 10 2 .99 + 2.02 2.95E-01 1.00E00 dipeptide transmembrane transport (GO:0035442) 5 1 .49 + 2.02 4.32E-01 1.00E00 ADP transport (GO:0015866) 5 1 .49 + 2.02 4.32E-01 1.00E00 pyrimidine nucleoside transport (GO:0015864) 5 1 .49 + 2.02 4.32E-01 1.00E00 uridine transport (GO:0015862) 5 1 .49 + 2.02 4.32E-01 1.00E00 ribonucleoside diphosphate catabolic process (GO:0009191) 10 2 .99 + 2.02 2.95E-01 1.00E00 copper ion transmembrane transport (GO:0035434) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of SMAD protein complex assembly (GO:0010990) 5 1 .49 + 2.02 4.32E-01 1.00E00 cellular magnesium ion homeostasis (GO:0010961) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of vitamin D biosynthetic process (GO:0010957) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of cellular response to heat (GO:1900034) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of macrophage cytokine production (GO:0010936) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of protein kinase C activity (GO:1900020) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of bone mineralization (GO:0030502) 15 3 1.48 + 2.02 2.17E-01 1.00E00 regulation of protein kinase C activity (GO:1900019) 5 1 .49 + 2.02 4.32E-01 1.00E00 ether lipid biosynthetic process (GO:0008611) 10 2 .99 + 2.02 2.95E-01 1.00E00 positive regulation of isomerase activity (GO:0010912) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of isomerase activity (GO:0010911) 5 1 .49 + 2.02 4.32E-01 1.00E00 response to sodium arsenite (GO:1903935) 5 1 .49 + 2.02 4.32E-01 1.00E00 cellular triglyceride homeostasis (GO:0035356) 5 1 .49 + 2.02 4.32E-01 1.00E00 long-chain fatty-acyl-CoA metabolic process (GO:0035336) 10 2 .99 + 2.02 2.95E-01 1.00E00 homoserine metabolic process (GO:0009092) 5 1 .49 + 2.02 4.32E-01 1.00E00 wound healing, spreading of epidermal cells (GO:0035313) 5 1 .49 + 2.02 4.32E-01 1.00E00 lactate transport (GO:0015727) 5 1 .49 + 2.02 4.32E-01 1.00E00 monocarboxylic acid transport (GO:0015718) 60 12 5.93 + 2.02 3.53E-02 4.99E-01 regulation of follicle-stimulating hormone secretion (GO:0046880) 5 1 .49 + 2.02 4.32E-01 1.00E00 AV node cell to bundle of His cell signaling (GO:0086027) 5 1 .49 + 2.02 4.32E-01 1.00E00 AV node cell action potential (GO:0086016) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of odontogenesis (GO:0042481) 15 3 1.48 + 2.02 2.17E-01 1.00E00 regulation of triglyceride catabolic process (GO:0010896) 10 2 .99 + 2.02 2.95E-01 1.00E00 axon choice point recognition (GO:0016198) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of sequestering of triglyceride (GO:0010891) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of synaptic assembly at neuromuscular junction (GO:0008582) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of lipid storage (GO:0010884) 20 4 1.98 + 2.02 2.68E-01 1.00E00 mast cell migration (GO:0097531) 5 1 .49 + 2.02 4.32E-01 1.00E00 norepinephrine biosynthetic process (GO:0042421) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of cholesterol esterification (GO:0010872) 10 2 .99 + 2.02 2.95E-01 1.00E00 positive regulation of gastro-intestinal system smooth muscle contraction (GO:1904306) 5 1 .49 + 2.02 4.32E-01 1.00E00 cranial ganglion development (GO:0061550) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of production of miRNAs involved in gene silencing by miRNA (GO:1903800) 10 2 .99 + 2.02 2.95E-01 1.00E00 regulation of deacetylase activity (GO:0150065) 10 2 .99 + 2.02 2.95E-01 1.00E00 regulation of iron ion transmembrane transport (GO:0034759) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of macrophage chemotaxis (GO:0010758) 30 6 2.97 + 2.02 1.33E-01 9.89E-01 hematopoietic stem cell homeostasis (GO:0061484) 25 5 2.47 + 2.02 1.86E-01 1.00E00 positive regulation of hydrogen peroxide metabolic process (GO:0010726) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of norepinephrine secretion (GO:0010700) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of potassium ion export across plasma membrane (GO:1903764) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of phospholipid metabolic process (GO:1903726) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of hemopoiesis (GO:1903707) 95 19 9.39 + 2.02 7.77E-03 1.79E-01 cardiac vascular smooth muscle cell development (GO:0060948) 5 1 .49 + 2.02 4.32E-01 1.00E00 folic acid metabolic process (GO:0046655) 5 1 .49 + 2.02 4.32E-01 1.00E00 vocal learning (GO:0042297) 5 1 .49 + 2.02 4.32E-01 1.00E00 sinoatrial node cell differentiation (GO:0060921) 5 1 .49 + 2.02 4.32E-01 1.00E00 alpha-beta T cell differentiation (GO:0046632) 65 13 6.43 + 2.02 2.68E-02 4.19E-01 cellular lipid biosynthetic process (GO:0097384) 10 2 .99 + 2.02 2.95E-01 1.00E00 establishment of Sertoli cell barrier (GO:0097368) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of alkaline phosphatase activity (GO:0010693) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of platelet-derived growth factor receptor signaling pathway (GO:0010641) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of chaperone-mediated protein folding (GO:1903644) 5 1 .49 + 2.02 4.32E-01 1.00E00 BMP signaling pathway involved in heart development (GO:0061312) 5 1 .49 + 2.02 4.32E-01 1.00E00 cardiac neural crest cell differentiation involved in heart development (GO:0061307) 10 2 .99 + 2.02 2.95E-01 1.00E00 CD40 signaling pathway (GO:0023035) 10 2 .99 + 2.02 2.95E-01 1.00E00 endothelial cell fate commitment (GO:0060839) 5 1 .49 + 2.02 4.32E-01 1.00E00 glycerol ether biosynthetic process (GO:0046504) 10 2 .99 + 2.02 2.95E-01 1.00E00 negative regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002924) 10 2 .99 + 2.02 2.95E-01 1.00E00 regulation of humoral immune response (GO:0002920) 35 7 3.46 + 2.02 9.79E-02 8.60E-01 positive regulation of phospholipase activity (GO:0010518) 40 8 3.95 + 2.02 7.36E-02 7.48E-01 negative regulation of mature B cell apoptotic process (GO:0002906) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of mature B cell apoptotic process (GO:0002905) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of B cell apoptotic process (GO:0002904) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of B cell apoptotic process (GO:0002902) 20 4 1.98 + 2.02 2.68E-01 1.00E00 positive regulation of membrane tubulation (GO:1903527) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768) 10 2 .99 + 2.02 2.95E-01 1.00E00 ether lipid metabolic process (GO:0046485) 15 3 1.48 + 2.02 2.17E-01 1.00E00 response to cisplatin (GO:0072718) 5 1 .49 + 2.02 4.32E-01 1.00E00 mammary gland branching involved in thelarche (GO:0060744) 5 1 .49 + 2.02 4.32E-01 1.00E00 monoacylglycerol metabolic process (GO:0046462) 10 2 .99 + 2.02 2.95E-01 1.00E00 late endosome to Golgi transport (GO:0034499) 5 1 .49 + 2.02 4.32E-01 1.00E00 prostate gland growth (GO:0060736) 10 2 .99 + 2.02 2.95E-01 1.00E00 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target (GO:0002860) 5 1 .49 + 2.02 4.32E-01 1.00E00 artery smooth muscle contraction (GO:0014824) 10 2 .99 + 2.02 2.95E-01 1.00E00 positive regulation of cell fate commitment (GO:0010455) 5 1 .49 + 2.02 4.32E-01 1.00E00 hypothalamus cell differentiation (GO:0021979) 5 1 .49 + 2.02 4.32E-01 1.00E00 formation of radial glial scaffolds (GO:0021943) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of cerebellar granule cell precursor proliferation (GO:0021940) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation (GO:0003256) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling (GO:0060665) 5 1 .49 + 2.02 4.32E-01 1.00E00 salivary gland cavitation (GO:0060662) 5 1 .49 + 2.02 4.32E-01 1.00E00 growth involved in heart morphogenesis (GO:0003241) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of smooth muscle cell apoptotic process (GO:0034392) 10 2 .99 + 2.02 2.95E-01 1.00E00 positive regulation of ER to Golgi vesicle-mediated transport (GO:1902953) 5 1 .49 + 2.02 4.32E-01 1.00E00 very-low-density lipoprotein particle remodeling (GO:0034372) 5 1 .49 + 2.02 4.32E-01 1.00E00 tube lumen cavitation (GO:0060605) 5 1 .49 + 2.02 4.32E-01 1.00E00 branch elongation of an epithelium (GO:0060602) 15 3 1.48 + 2.02 2.17E-01 1.00E00 regulation of fatty acid oxidation (GO:0046320) 30 6 2.97 + 2.02 1.33E-01 9.89E-01 motor neuron apoptotic process (GO:0097049) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of muscle adaptation (GO:0014744) 5 1 .49 + 2.02 4.32E-01 1.00E00 COP9 signalosome assembly (GO:0010387) 5 1 .49 + 2.02 4.32E-01 1.00E00 immune response-inhibiting cell surface receptor signaling pathway (GO:0002767) 5 1 .49 + 2.02 4.32E-01 1.00E00 response to granulocyte macrophage colony-stimulating factor (GO:0097012) 10 2 .99 + 2.02 2.95E-01 1.00E00 positive regulation of phospholipid translocation (GO:0061092) 5 1 .49 + 2.02 4.32E-01 1.00E00 negative regulation of cell growth involved in cardiac muscle cell development (GO:0061052) 10 2 .99 + 2.02 2.95E-01 1.00E00 establishment of endothelial barrier (GO:0061028) 30 6 2.97 + 2.02 1.33E-01 9.88E-01 mitral valve morphogenesis (GO:0003183) 10 2 .99 + 2.02 2.95E-01 1.00E00 mitral valve development (GO:0003174) 10 2 .99 + 2.02 2.95E-01 1.00E00 sinoatrial node development (GO:0003163) 5 1 .49 + 2.02 4.32E-01 1.00E00 morphogenesis of an epithelial bud (GO:0060572) 5 1 .49 + 2.02 4.32E-01 1.00E00 membranous septum morphogenesis (GO:0003149) 10 2 .99 + 2.02 2.95E-01 1.00E00 positive regulation of secondary heart field cardioblast proliferation (GO:0072513) 5 1 .49 + 2.02 4.32E-01 1.00E00 positive regulation of macrophage fusion (GO:0034241) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of synaptic vesicle transport (GO:1902803) 5 1 .49 + 2.02 4.32E-01 1.00E00 somatic recombination of T cell receptor gene segments (GO:0002681) 5 1 .49 + 2.02 4.32E-01 1.00E00 tRNA thio-modification (GO:0034227) 5 1 .49 + 2.02 4.32E-01 1.00E00 regulation of myeloid leukocyte differentiation (GO:0002761) 116 23 11.47 + 2.01 4.10E-03 1.07E-01 cytokine production (GO:0001816) 106 21 10.48 + 2.00 7.10E-03 1.67E-01 organic acid transmembrane transport (GO:1903825) 96 19 9.49 + 2.00 8.27E-03 1.88E-01 regulation of nucleotide metabolic process (GO:0006140) 71 14 7.02 + 1.99 2.21E-02 3.69E-01 regulation of purine nucleotide metabolic process (GO:1900542) 71 14 7.02 + 1.99 2.21E-02 3.68E-01 cellular biogenic amine metabolic process (GO:0006576) 66 13 6.53 + 1.99 2.85E-02 4.42E-01 regulation of cell-cell adhesion (GO:0022407) 391 77 38.66 + 1.99 1.71E-07 2.18E-05 positive regulation of fat cell differentiation (GO:0045600) 61 12 6.03 + 1.99 3.73E-02 5.18E-01 negative regulation of endopeptidase activity (GO:0010951) 117 23 11.57 + 1.99 4.32E-03 1.12E-01 cardiac muscle contraction (GO:0060048) 56 11 5.54 + 1.99 4.95E-02 5.99E-01 modulation by host of symbiont process (GO:0051851) 56 11 5.54 + 1.99 4.95E-02 5.99E-01 regulation of T cell activation (GO:0050863) 296 58 29.27 + 1.98 7.70E-06 6.15E-04 regulation of lipid kinase activity (GO:0043550) 46 9 4.55 + 1.98 9.13E-02 8.52E-01 regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) 46 9 4.55 + 1.98 9.13E-02 8.51E-01 positive regulation of immunoglobulin mediated immune response (GO:0002891) 41 8 4.05 + 1.97 7.92E-02 7.94E-01 positive regulation of protein tyrosine kinase activity (GO:0061098) 41 8 4.05 + 1.97 7.92E-02 7.94E-01 positive regulation of B cell mediated immunity (GO:0002714) 41 8 4.05 + 1.97 7.92E-02 7.93E-01 cell-substrate adhesion (GO:0031589) 154 30 15.23 + 1.97 1.60E-03 5.23E-02 taxis (GO:0042330) 380 74 37.57 + 1.97 4.41E-07 4.96E-05 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002824) 113 22 11.17 + 1.97 5.89E-03 1.42E-01 positive regulation of Notch signaling pathway (GO:0045747) 36 7 3.56 + 1.97 1.05E-01 9.00E-01 regulation of endothelial cell differentiation (GO:0045601) 36 7 3.56 + 1.97 1.05E-01 8.99E-01 regulation of glial cell proliferation (GO:0060251) 36 7 3.56 + 1.97 1.05E-01 8.99E-01 positive regulation of interleukin-10 production (GO:0032733) 36 7 3.56 + 1.97 1.05E-01 8.98E-01 positive regulation of calcium-mediated signaling (GO:0050850) 36 7 3.56 + 1.97 1.05E-01 8.98E-01 regulation of sprouting angiogenesis (GO:1903670) 36 7 3.56 + 1.97 1.05E-01 8.97E-01 negative regulation of cation transmembrane transport (GO:1904063) 72 14 7.12 + 1.97 3.43E-02 4.91E-01 lamellipodium assembly (GO:0030032) 36 7 3.56 + 1.97 1.05E-01 8.97E-01 response to cytokine (GO:0034097) 654 127 64.66 + 1.96 3.56E-11 7.11E-09 chemotaxis (GO:0006935) 376 73 37.18 + 1.96 5.94E-07 6.34E-05 regulation of calcium-mediated signaling (GO:0050848) 67 13 6.62 + 1.96 3.04E-02 4.52E-01 cellular amine metabolic process (GO:0044106) 67 13 6.62 + 1.96 3.04E-02 4.52E-01 regulation of leukocyte mediated immunity (GO:0002703) 232 45 22.94 + 1.96 1.11E-04 5.70E-03 response to external stimulus (GO:0009605) 1694 328 167.49 + 1.96 3.81E-29 5.79E-26 regulation of homotypic cell-cell adhesion (GO:0034110) 31 6 3.07 + 1.96 1.41E-01 1.00E00 CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) 31 6 3.07 + 1.96 1.41E-01 1.00E00 positive regulation of leukocyte apoptotic process (GO:2000108) 31 6 3.07 + 1.96 1.41E-01 1.00E00 positive regulation of potassium ion transmembrane transport (GO:1901381) 31 6 3.07 + 1.96 1.41E-01 1.00E00 regulation of digestive system process (GO:0044058) 31 6 3.07 + 1.96 1.41E-01 1.00E00 cellular modified amino acid biosynthetic process (GO:0042398) 31 6 3.07 + 1.96 1.41E-01 1.00E00 negative regulation of blood coagulation (GO:0030195) 31 6 3.07 + 1.96 1.41E-01 1.00E00 secondary metabolic process (GO:0019748) 31 6 3.07 + 1.96 1.41E-01 1.00E00 T-helper cell differentiation (GO:0042093) 31 6 3.07 + 1.96 1.41E-01 1.00E00 positive regulation of T cell differentiation (GO:0045582) 93 18 9.20 + 1.96 1.20E-02 2.47E-01 negative regulation of response to external stimulus (GO:0032102) 306 59 30.25 + 1.95 1.06E-05 8.00E-04 cellular transition metal ion homeostasis (GO:0046916) 83 16 8.21 + 1.95 2.02E-02 3.48E-01 positive regulation of lipid metabolic process (GO:0045834) 135 26 13.35 + 1.95 3.25E-03 9.05E-02 glial cell development (GO:0021782) 104 20 10.28 + 1.95 1.05E-02 2.26E-01 modulation by host of viral process (GO:0044788) 26 5 2.57 + 1.95 1.95E-01 1.00E00 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902042) 26 5 2.57 + 1.95 1.95E-01 1.00E00 response to interleukin-4 (GO:0070670) 26 5 2.57 + 1.95 1.95E-01 1.00E00 epidermis morphogenesis (GO:0048730) 26 5 2.57 + 1.95 1.95E-01 1.00E00 positive regulation of ubiquitin-protein transferase activity (GO:0051443) 26 5 2.57 + 1.95 1.95E-01 1.00E00 sodium ion homeostasis (GO:0055078) 26 5 2.57 + 1.95 1.95E-01 1.00E00 negative regulation of cardiac muscle hypertrophy (GO:0010614) 26 5 2.57 + 1.95 1.95E-01 1.00E00 negative regulation of muscle contraction (GO:0045932) 26 5 2.57 + 1.95 1.95E-01 1.00E00 plasma membrane organization (GO:0007009) 99 19 9.79 + 1.94 1.38E-02 2.69E-01 regulation of response to external stimulus (GO:0032101) 766 147 75.74 + 1.94 1.77E-12 4.32E-10 actin filament-based movement (GO:0030048) 73 14 7.22 + 1.94 3.54E-02 4.96E-01 immune system development (GO:0002520) 678 130 67.03 + 1.94 3.27E-11 6.62E-09 positive regulation of adaptive immune response (GO:0002821) 120 23 11.86 + 1.94 7.33E-03 1.70E-01 regulation of erythrocyte differentiation (GO:0045646) 47 9 4.65 + 1.94 9.41E-02 8.70E-01 collagen metabolic process (GO:0032963) 47 9 4.65 + 1.94 9.41E-02 8.70E-01 cellular response to cytokine stimulus (GO:0071345) 570 109 56.36 + 1.93 1.67E-09 2.99E-07 apoptotic process involved in development (GO:1902742) 21 4 2.08 + 1.93 2.77E-01 1.00E00 telencephalon glial cell migration (GO:0022030) 21 4 2.08 + 1.93 2.77E-01 1.00E00 central nervous system myelination (GO:0022010) 21 4 2.08 + 1.93 2.77E-01 1.00E00 phospholipase C-activating G protein-coupled receptor signaling pathway (GO:0007200) 63 12 6.23 + 1.93 4.19E-02 5.55E-01 definitive hemopoiesis (GO:0060216) 21 4 2.08 + 1.93 2.77E-01 1.00E00 phospholipid translocation (GO:0045332) 42 8 4.15 + 1.93 8.53E-02 8.33E-01 natural killer cell differentiation (GO:0001779) 21 4 2.08 + 1.93 2.77E-01 1.00E00 stem cell proliferation (GO:0072089) 21 4 2.08 + 1.93 2.77E-01 1.00E00 response to dietary excess (GO:0002021) 21 4 2.08 + 1.93 2.77E-01 1.00E00 regulation of bone resorption (GO:0045124) 42 8 4.15 + 1.93 8.53E-02 8.33E-01 cellular response to glucose stimulus (GO:0071333) 42 8 4.15 + 1.93 8.53E-02 8.32E-01 axon ensheathment in central nervous system (GO:0032291) 21 4 2.08 + 1.93 2.77E-01 1.00E00 detoxification (GO:0098754) 42 8 4.15 + 1.93 8.53E-02 8.32E-01 myeloid dendritic cell differentiation (GO:0043011) 21 4 2.08 + 1.93 2.77E-01 1.00E00 filopodium assembly (GO:0046847) 21 4 2.08 + 1.93 2.77E-01 1.00E00 regulation of protein kinase A signaling (GO:0010738) 21 4 2.08 + 1.93 2.77E-01 1.00E00 positive regulation of alpha-beta T cell activation (GO:0046635) 63 12 6.23 + 1.93 4.19E-02 5.54E-01 T cell differentiation (GO:0030217) 168 32 16.61 + 1.93 1.63E-03 5.31E-02 heparan sulfate proteoglycan metabolic process (GO:0030201) 21 4 2.08 + 1.93 2.77E-01 1.00E00 amino acid transmembrane transport (GO:0003333) 63 12 6.23 + 1.93 4.19E-02 5.54E-01 response to type I interferon (GO:0034340) 21 4 2.08 + 1.93 2.77E-01 1.00E00 cerebral cortex radial glia guided migration (GO:0021801) 21 4 2.08 + 1.93 2.77E-01 1.00E00 regulation of interferon-beta production (GO:0032648) 58 11 5.73 + 1.92 5.48E-02 6.40E-01 positive regulation of type I interferon production (GO:0032481) 58 11 5.73 + 1.92 5.48E-02 6.39E-01 response to glucocorticoid (GO:0051384) 58 11 5.73 + 1.92 5.48E-02 6.39E-01 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002822) 174 33 17.20 + 1.92 1.28E-03 4.42E-02 regulation of adaptive immune response (GO:0002819) 190 36 18.79 + 1.92 9.01E-04 3.33E-02 digestive tract morphogenesis (GO:0048546) 37 7 3.66 + 1.91 1.12E-01 9.22E-01 regulation of alpha-beta T cell proliferation (GO:0046640) 37 7 3.66 + 1.91 1.12E-01 9.22E-01 regulation of hemopoiesis (GO:1903706) 344 65 34.01 + 1.91 6.29E-06 5.13E-04 regulation of tissue remodeling (GO:0034103) 69 13 6.82 + 1.91 4.89E-02 6.00E-01 triglyceride biosynthetic process (GO:0019432) 16 3 1.58 + 1.90 2.41E-01 1.00E00 negative regulation of homotypic cell-cell adhesion (GO:0034111) 16 3 1.58 + 1.90 2.41E-01 1.00E00 regulation of B cell differentiation (GO:0045577) 32 6 3.16 + 1.90 1.50E-01 1.00E00 cell migration in hindbrain (GO:0021535) 16 3 1.58 + 1.90 2.41E-01 1.00E00 positive regulation of receptor recycling (GO:0001921) 16 3 1.58 + 1.90 2.41E-01 1.00E00 regulation of lipase activity (GO:0060191) 64 12 6.33 + 1.90 4.47E-02 5.59E-01 phosphatidylcholine biosynthetic process (GO:0006656) 16 3 1.58 + 1.90 2.41E-01 1.00E00 regulation of endothelial cell chemotaxis (GO:2001026) 16 3 1.58 + 1.90 2.41E-01 1.00E00 modulation by virus of host process (GO:0019048) 16 3 1.58 + 1.90 2.41E-01 1.00E00 autophagy of nucleus (GO:0044804) 16 3 1.58 + 1.90 2.41E-01 1.00E00 hematopoietic stem cell proliferation (GO:0071425) 16 3 1.58 + 1.90 2.41E-01 1.00E00 glial cell proliferation (GO:0014009) 16 3 1.58 + 1.90 2.41E-01 1.00E00 neurotransmitter uptake (GO:0001504) 16 3 1.58 + 1.90 2.41E-01 1.00E00 cellular response to corticosteroid stimulus (GO:0071384) 32 6 3.16 + 1.90 1.50E-01 1.00E00 positive regulation of calcineurin-NFAT signaling cascade (GO:0070886) 16 3 1.58 + 1.90 2.41E-01 1.00E00 regulation of calcineurin-NFAT signaling cascade (GO:0070884) 32 6 3.16 + 1.90 1.50E-01 1.00E00 regulation of prostaglandin secretion (GO:0032306) 16 3 1.58 + 1.90 2.41E-01 1.00E00 regulation of branching involved in ureteric bud morphogenesis (GO:0090189) 16 3 1.58 + 1.90 2.41E-01 1.00E00 positive regulation of calcineurin-mediated signaling (GO:0106058) 16 3 1.58 + 1.90 2.41E-01 1.00E00 regulation of calcineurin-mediated signaling (GO:0106056) 32 6 3.16 + 1.90 1.50E-01 1.00E00 detection of other organism (GO:0098543) 16 3 1.58 + 1.90 2.41E-01 1.00E00 nucleoside monophosphate catabolic process (GO:0009125) 16 3 1.58 + 1.90 2.41E-01 1.00E00 negative regulation of hemostasis (GO:1900047) 32 6 3.16 + 1.90 1.50E-01 1.00E00 cGMP-mediated signaling (GO:0019934) 16 3 1.58 + 1.90 2.41E-01 1.00E00 natural killer cell mediated cytotoxicity (GO:0042267) 16 3 1.58 + 1.90 2.41E-01 1.00E00 negative regulation of platelet activation (GO:0010544) 16 3 1.58 + 1.90 2.41E-01 1.00E00 T cell selection (GO:0045058) 48 9 4.75 + 1.90 9.75E-02 8.59E-01 positive regulation of endocytosis (GO:0045807) 112 21 11.07 + 1.90 9.42E-03 2.07E-01 regulation of innate immune response (GO:0045088) 171 32 16.91 + 1.89 1.79E-03 5.65E-02 reactive oxygen species metabolic process (GO:0072593) 75 14 7.42 + 1.89 3.81E-02 5.29E-01 positive regulation of innate immune response (GO:0045089) 102 19 10.08 + 1.88 1.56E-02 2.90E-01 receptor-mediated endocytosis (GO:0006898) 129 24 12.75 + 1.88 6.54E-03 1.56E-01 positive regulation of cytokine-mediated signaling pathway (GO:0001961) 43 8 4.25 + 1.88 1.33E-01 9.89E-01 cellular response to hexose stimulus (GO:0071331) 43 8 4.25 + 1.88 1.33E-01 9.89E-01 regulation of peptidyl-threonine phosphorylation (GO:0010799) 43 8 4.25 + 1.88 1.33E-01 9.88E-01 regulation of cellular response to insulin stimulus (GO:1900076) 70 13 6.92 + 1.88 5.05E-02 6.07E-01 regulation of syncytium formation by plasma membrane fusion (GO:0060142) 27 5 2.67 + 1.87 2.05E-01 1.00E00 regulation of interferon-alpha production (GO:0032647) 27 5 2.67 + 1.87 2.05E-01 1.00E00 chondroitin sulfate proteoglycan metabolic process (GO:0050654) 27 5 2.67 + 1.87 2.05E-01 1.00E00 response to pain (GO:0048265) 27 5 2.67 + 1.87 2.05E-01 1.00E00 regulation of ruffle assembly (GO:1900027) 27 5 2.67 + 1.87 2.05E-01 1.00E00 cardiac muscle cell contraction (GO:0086003) 27 5 2.67 + 1.87 2.05E-01 1.00E00 negative regulation of protein localization to cell periphery (GO:1904376) 27 5 2.67 + 1.87 2.05E-01 1.00E00 coronary vasculature morphogenesis (GO:0060977) 27 5 2.67 + 1.87 2.05E-01 1.00E00 negative regulation of muscle hypertrophy (GO:0014741) 27 5 2.67 + 1.87 2.05E-01 1.00E00 positive regulation of leukocyte mediated immunity (GO:0002705) 135 25 13.35 + 1.87 7.52E-03 1.74E-01 lipid transport (GO:0006869) 211 39 20.86 + 1.87 7.24E-04 2.80E-02 regulation of calcium ion import (GO:0090279) 38 7 3.76 + 1.86 1.20E-01 9.69E-01 amino sugar metabolic process (GO:0006040) 38 7 3.76 + 1.86 1.20E-01 9.68E-01 regulation of response to reactive oxygen species (GO:1901031) 38 7 3.76 + 1.86 1.20E-01 9.68E-01 negative regulation of leukocyte migration (GO:0002686) 38 7 3.76 + 1.86 1.20E-01 9.67E-01 wound healing (GO:0042060) 201 37 19.87 + 1.86 1.23E-03 4.32E-02 modulation by symbiont of entry into host (GO:0052372) 49 9 4.84 + 1.86 1.01E-01 8.80E-01 regulation of leukocyte differentiation (GO:1902105) 278 51 27.49 + 1.86 1.25E-04 6.27E-03 response to corticosteroid (GO:0031960) 60 11 5.93 + 1.85 6.14E-02 6.95E-01 regulation of viral life cycle (GO:1903900) 131 24 12.95 + 1.85 1.01E-02 2.21E-01 regulation of glial cell differentiation (GO:0045685) 71 13 7.02 + 1.85 5.23E-02 6.25E-01 regulation of lymphocyte differentiation (GO:0045619) 175 32 17.30 + 1.85 3.00E-03 8.52E-02 positive regulation of cell migration (GO:0030335) 500 91 49.44 + 1.84 3.33E-07 3.86E-05 protein-lipid complex subunit organization (GO:0071825) 33 6 3.26 + 1.84 1.59E-01 1.00E00 alpha-beta T cell differentiation involved in immune response (GO:0002293) 33 6 3.26 + 1.84 1.59E-01 1.00E00 regulation of polysaccharide biosynthetic process (GO:0032885) 33 6 3.26 + 1.84 1.59E-01 1.00E00 positive regulation of purine nucleotide metabolic process (GO:1900544) 33 6 3.26 + 1.84 1.59E-01 1.00E00 regulation of mast cell degranulation (GO:0043304) 33 6 3.26 + 1.84 1.59E-01 1.00E00 response to pH (GO:0009268) 33 6 3.26 + 1.84 1.59E-01 1.00E00 regulation of platelet activation (GO:0010543) 33 6 3.26 + 1.84 1.59E-01 1.00E00 positive regulation of nucleotide metabolic process (GO:0045981) 33 6 3.26 + 1.84 1.59E-01 1.00E00 negative regulation of leukocyte mediated immunity (GO:0002704) 66 12 6.53 + 1.84 6.95E-02 7.20E-01 lipid translocation (GO:0034204) 44 8 4.35 + 1.84 1.37E-01 1.00E00 negative regulation of endothelial cell differentiation (GO:0045602) 11 2 1.09 + 1.84 3.29E-01 1.00E00 hexose biosynthetic process (GO:0019319) 22 4 2.18 + 1.84 2.88E-01 1.00E00 negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394) 11 2 1.09 + 1.84 3.29E-01 1.00E00 innervation (GO:0060384) 22 4 2.18 + 1.84 2.88E-01 1.00E00 adenylate cyclase-activating adrenergic receptor signaling pathway (GO:0071880) 11 2 1.09 + 1.84 3.29E-01 1.00E00 metanephric nephron epithelium development (GO:0072243) 11 2 1.09 + 1.84 3.29E-01 1.00E00 T cell mediated cytotoxicity (GO:0001913) 11 2 1.09 + 1.84 3.29E-01 1.00E00 locomotor rhythm (GO:0045475) 11 2 1.09 + 1.84 3.29E-01 1.00E00 nonribosomal peptide biosynthetic process (GO:0019184) 11 2 1.09 + 1.84 3.29E-01 1.00E00 epithelial cell fate commitment (GO:0072148) 11 2 1.09 + 1.84 3.29E-01 1.00E00 positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) 22 4 2.18 + 1.84 2.88E-01 1.00E00 commissural neuron axon guidance (GO:0071679) 11 2 1.09 + 1.84 3.29E-01 1.00E00 negative regulation of transforming growth factor beta production (GO:0071635) 11 2 1.09 + 1.84 3.29E-01 1.00E00 positive regulation of MHC class II biosynthetic process (GO:0045348) 11 2 1.09 + 1.84 3.29E-01 1.00E00 thyroid hormone generation (GO:0006590) 11 2 1.09 + 1.84 3.29E-01 1.00E00 otic vesicle development (GO:0071599) 11 2 1.09 + 1.84 3.29E-01 1.00E00 membrane protein ectodomain proteolysis (GO:0006509) 22 4 2.18 + 1.84 2.88E-01 1.00E00 negative regulation of lymphocyte migration (GO:2000402) 11 2 1.09 + 1.84 3.29E-01 1.00E00 ganglioside metabolic process (GO:0001573) 22 4 2.18 + 1.84 2.88E-01 1.00E00 interleukin-1 production (GO:0032612) 11 2 1.09 + 1.84 3.29E-01 1.00E00 interleukin-1 beta production (GO:0032611) 11 2 1.09 + 1.84 3.29E-01 1.00E00 cellular response to cholesterol (GO:0071397) 11 2 1.09 + 1.84 3.29E-01 1.00E00 regulation of hair follicle development (GO:0051797) 11 2 1.09 + 1.84 3.29E-01 1.00E00 cellular response to interleukin-6 (GO:0071354) 22 4 2.18 + 1.84 2.88E-01 1.00E00 cellular response to monosaccharide stimulus (GO:0071326) 44 8 4.35 + 1.84 1.37E-01 1.00E00 protein mono-ADP-ribosylation (GO:0140289) 11 2 1.09 + 1.84 3.29E-01 1.00E00 negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) 11 2 1.09 + 1.84 3.29E-01 1.00E00 ether biosynthetic process (GO:1901503) 11 2 1.09 + 1.84 3.29E-01 1.00E00 response to interleukin-6 (GO:0070741) 22 4 2.18 + 1.84 2.88E-01 1.00E00 negative regulation of cysteine-type endopeptidase activity (GO:2000117) 77 14 7.61 + 1.84 4.17E-02 5.53E-01 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress (GO:1990440) 11 2 1.09 + 1.84 3.29E-01 1.00E00 neuron projection arborization (GO:0140058) 11 2 1.09 + 1.84 3.29E-01 1.00E00 positive regulation of positive chemotaxis (GO:0050927) 22 4 2.18 + 1.84 2.88E-01 1.00E00 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway (GO:0106072) 11 2 1.09 + 1.84 3.29E-01 1.00E00 detection of chemical stimulus involved in sensory perception of taste (GO:0050912) 11 2 1.09 + 1.84 3.29E-01 1.00E00 regulation of transcription from RNA polymerase II promoter in response to stress (GO:0043618) 44 8 4.35 + 1.84 1.37E-01 1.00E00 receptor internalization (GO:0031623) 55 10 5.44 + 1.84 8.01E-02 8.02E-01 regulation of fever generation (GO:0031620) 11 2 1.09 + 1.84 3.29E-01 1.00E00 regulation of appetite (GO:0032098) 11 2 1.09 + 1.84 3.29E-01 1.00E00 mesodermal cell differentiation (GO:0048333) 11 2 1.09 + 1.84 3.29E-01 1.00E00 protein homotrimerization (GO:0070207) 11 2 1.09 + 1.84 3.29E-01 1.00E00 negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) 22 4 2.18 + 1.84 2.88E-01 1.00E00 positive regulation of vesicle fusion (GO:0031340) 11 2 1.09 + 1.84 3.29E-01 1.00E00 positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:0036003) 22 4 2.18 + 1.84 2.88E-01 1.00E00 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) 22 4 2.18 + 1.84 2.88E-01 1.00E00 purine deoxyribonucleotide catabolic process (GO:0009155) 11 2 1.09 + 1.84 3.29E-01 1.00E00 positive regulation of anion transmembrane transport (GO:1903961) 11 2 1.09 + 1.84 3.29E-01 1.00E00 regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358) 11 2 1.09 + 1.84 3.29E-01 1.00E00 regulation of sequestering of triglyceride (GO:0010889) 11 2 1.09 + 1.84 3.29E-01 1.00E00 glycerophospholipid catabolic process (GO:0046475) 22 4 2.18 + 1.84 2.88E-01 1.00E00 phosphatidylcholine metabolic process (GO:0046470) 44 8 4.35 + 1.84 1.37E-01 1.00E00 negative regulation of inflammatory response to antigenic stimulus (GO:0002862) 11 2 1.09 + 1.84 3.29E-01 1.00E00 actin filament depolymerization (GO:0030042) 11 2 1.09 + 1.84 3.29E-01 1.00E00 tonic smooth muscle contraction (GO:0014820) 11 2 1.09 + 1.84 3.29E-01 1.00E00 regulation of skeletal muscle contraction (GO:0014819) 11 2 1.09 + 1.84 3.29E-01 1.00E00 negative regulation of complement activation (GO:0045916) 11 2 1.09 + 1.84 3.29E-01 1.00E00 regulation of branching involved in salivary gland morphogenesis (GO:0060693) 11 2 1.09 + 1.84 3.29E-01 1.00E00 low-density lipoprotein particle clearance (GO:0034383) 11 2 1.09 + 1.84 3.29E-01 1.00E00 heart valve formation (GO:0003188) 11 2 1.09 + 1.84 3.29E-01 1.00E00 second-messenger-mediated signaling (GO:0019932) 149 27 14.73 + 1.83 5.24E-03 1.30E-01 positive regulation of neuron death (GO:1901216) 116 21 11.47 + 1.83 1.53E-02 2.87E-01 regulation of response to cytokine stimulus (GO:0060759) 116 21 11.47 + 1.83 1.53E-02 2.86E-01 import across plasma membrane (GO:0098739) 105 19 10.38 + 1.83 2.55E-02 4.04E-01 regeneration (GO:0031099) 83 15 8.21 + 1.83 4.82E-02 5.93E-01 negative regulation of small molecule metabolic process (GO:0062014) 83 15 8.21 + 1.83 4.82E-02 5.92E-01 regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) 61 11 6.03 + 1.82 9.32E-02 8.62E-01 neuromuscular process controlling balance (GO:0050885) 50 9 4.94 + 1.82 1.06E-01 8.98E-01 positive regulation of DNA binding (GO:0043388) 50 9 4.94 + 1.82 1.06E-01 8.97E-01 regulation of bone remodeling (GO:0046850) 50 9 4.94 + 1.82 1.06E-01 8.97E-01 regulation of peptidyl-tyrosine phosphorylation (GO:0050730) 228 41 22.54 + 1.82 7.82E-04 2.96E-02 amide transport (GO:0042886) 89 16 8.80 + 1.82 3.74E-02 5.20E-01 regulation of ERK1 and ERK2 cascade (GO:0070372) 256 46 25.31 + 1.82 3.53E-04 1.52E-02 striated muscle contraction (GO:0006941) 78 14 7.71 + 1.82 4.38E-02 5.51E-01 positive regulation of cell motility (GO:2000147) 513 92 50.72 + 1.81 4.67E-07 5.17E-05 regulation of pattern recognition receptor signaling pathway (GO:0062207) 95 17 9.39 + 1.81 2.98E-02 4.48E-01 regulation of receptor recycling (GO:0001919) 28 5 2.77 + 1.81 2.15E-01 1.00E00 myoblast differentiation (GO:0045445) 28 5 2.77 + 1.81 2.15E-01 1.00E00 excitatory postsynaptic potential (GO:0060079) 28 5 2.77 + 1.81 2.15E-01 1.00E00 positive regulation of mast cell activation (GO:0033005) 28 5 2.77 + 1.81 2.15E-01 1.00E00 endoplasmic reticulum calcium ion homeostasis (GO:0032469) 28 5 2.77 + 1.81 2.15E-01 1.00E00 proteoglycan metabolic process (GO:0006029) 56 10 5.54 + 1.81 8.45E-02 8.36E-01 cellular response to hydrogen peroxide (GO:0070301) 56 10 5.54 + 1.81 8.45E-02 8.36E-01 regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030947) 28 5 2.77 + 1.81 2.15E-01 1.00E00 positive regulation of viral life cycle (GO:1903902) 28 5 2.77 + 1.81 2.15E-01 1.00E00 positive regulation of locomotion (GO:0040017) 527 94 52.11 + 1.80 4.43E-07 4.94E-05 positive regulation of cell adhesion (GO:0045785) 405 72 40.04 + 1.80 1.39E-05 9.87E-04 response to ethanol (GO:0045471) 45 8 4.45 + 1.80 1.42E-01 1.00E00 liver development (GO:0001889) 90 16 8.90 + 1.80 3.87E-02 5.36E-01 aminoglycan biosynthetic process (GO:0006023) 45 8 4.45 + 1.80 1.42E-01 1.00E00 negative regulation of chemotaxis (GO:0050922) 45 8 4.45 + 1.80 1.42E-01 1.00E00 organic hydroxy compound transport (GO:0015850) 90 16 8.90 + 1.80 3.87E-02 5.35E-01 positive regulation of anion transport (GO:1903793) 45 8 4.45 + 1.80 1.42E-01 1.00E00 negative regulation of secretion by cell (GO:1903531) 135 24 13.35 + 1.80 1.14E-02 2.39E-01 mucopolysaccharide metabolic process (GO:1903510) 45 8 4.45 + 1.80 1.42E-01 1.00E00 regulation of tyrosine phosphorylation of STAT protein (GO:0042509) 62 11 6.13 + 1.79 9.55E-02 8.46E-01 glycosaminoglycan metabolic process (GO:0030203) 62 11 6.13 + 1.79 9.55E-02 8.45E-01 actin filament organization (GO:0007015) 226 40 22.34 + 1.79 1.12E-03 3.98E-02 negative regulation of blood pressure (GO:0045776) 34 6 3.36 + 1.78 1.69E-01 1.00E00 negative regulation of type I interferon-mediated signaling pathway (GO:0060339) 17 3 1.68 + 1.78 4.18E-01 1.00E00 Rho protein signal transduction (GO:0007266) 51 9 5.04 + 1.78 1.11E-01 9.18E-01 positive regulation of neurotransmitter secretion (GO:0001956) 17 3 1.68 + 1.78 4.18E-01 1.00E00 activation of phospholipase C activity (GO:0007202) 17 3 1.68 + 1.78 4.18E-01 1.00E00 glycerol ether metabolic process (GO:0006662) 17 3 1.68 + 1.78 4.18E-01 1.00E00 phosphatidylserine metabolic process (GO:0006658) 17 3 1.68 + 1.78 4.18E-01 1.00E00 alpha-beta T cell activation involved in immune response (GO:0002287) 34 6 3.36 + 1.78 1.69E-01 1.00E00 macrophage activation involved in immune response (GO:0002281) 17 3 1.68 + 1.78 4.18E-01 1.00E00 regulation of transforming growth factor beta production (GO:0071634) 34 6 3.36 + 1.78 1.69E-01 1.00E00 natural killer cell mediated immunity (GO:0002228) 17 3 1.68 + 1.78 4.18E-01 1.00E00 positive regulation of lymphocyte migration (GO:2000403) 34 6 3.36 + 1.78 1.69E-01 1.00E00 regulation of lymphocyte chemotaxis (GO:1901623) 17 3 1.68 + 1.78 4.18E-01 1.00E00 regulation of mast cell activation involved in immune response (GO:0033006) 34 6 3.36 + 1.78 1.69E-01 1.00E00 response to cholesterol (GO:0070723) 17 3 1.68 + 1.78 4.18E-01 1.00E00 positive regulation of hormone metabolic process (GO:0032352) 17 3 1.68 + 1.78 4.18E-01 1.00E00 positive regulation of icosanoid secretion (GO:0032305) 17 3 1.68 + 1.78 4.18E-01 1.00E00 regulation of cell migration involved in sprouting angiogenesis (GO:0090049) 34 6 3.36 + 1.78 1.69E-01 1.00E00 regulation of protein kinase C signaling (GO:0090036) 17 3 1.68 + 1.78 4.18E-01 1.00E00 regulation of anion transport (GO:0044070) 85 15 8.40 + 1.78 5.07E-02 6.09E-01 regulation of amyloid-beta clearance (GO:1900221) 17 3 1.68 + 1.78 4.18E-01 1.00E00 regulation of dopamine metabolic process (GO:0042053) 17 3 1.68 + 1.78 4.18E-01 1.00E00 fluid transport (GO:0042044) 17 3 1.68 + 1.78 4.18E-01 1.00E00 negative regulation of reactive oxygen species biosynthetic process (GO:1903427) 17 3 1.68 + 1.78 4.18E-01 1.00E00 plasma lipoprotein particle remodeling (GO:0034369) 17 3 1.68 + 1.78 4.18E-01 1.00E00 protein-lipid complex remodeling (GO:0034368) 17 3 1.68 + 1.78 4.18E-01 1.00E00 heart valve development (GO:0003170) 51 9 5.04 + 1.78 1.11E-01 9.17E-01 organic acid transport (GO:0015849) 182 32 17.99 + 1.78 3.77E-03 1.02E-01 renal system process (GO:0003014) 74 13 7.32 + 1.78 5.94E-02 6.82E-01 regulation of gliogenesis (GO:0014013) 97 17 9.59 + 1.77 3.26E-02 4.74E-01 neuropeptide signaling pathway (GO:0007218) 40 7 3.95 + 1.77 1.93E-01 1.00E00 regulation of T cell migration (GO:2000404) 40 7 3.95 + 1.77 1.93E-01 1.00E00 negative regulation of gliogenesis (GO:0014014) 40 7 3.95 + 1.77 1.93E-01 1.00E00 regulation of triglyceride metabolic process (GO:0090207) 40 7 3.95 + 1.77 1.93E-01 1.00E00 positive regulation of potassium ion transport (GO:0043268) 40 7 3.95 + 1.77 1.93E-01 1.00E00 regulation of epithelial cell apoptotic process (GO:1904035) 80 14 7.91 + 1.77 6.68E-02 7.39E-01 positive regulation of cellular component movement (GO:0051272) 526 92 52.01 + 1.77 1.29E-06 1.22E-04 positive regulation of NIK/NF-kappaB signaling (GO:1901224) 63 11 6.23 + 1.77 9.82E-02 8.62E-01 negative regulation of transport (GO:0051051) 401 70 39.65 + 1.77 2.67E-05 1.71E-03 import into cell (GO:0098657) 132 23 13.05 + 1.76 1.57E-02 2.92E-01 regulation of osteoblast proliferation (GO:0033688) 23 4 2.27 + 1.76 3.00E-01 1.00E00 cell adhesion mediated by integrin (GO:0033627) 23 4 2.27 + 1.76 3.00E-01 1.00E00 regulation of membrane repolarization (GO:0060306) 23 4 2.27 + 1.76 3.00E-01 1.00E00 regulation of positive chemotaxis (GO:0050926) 23 4 2.27 + 1.76 3.00E-01 1.00E00 triglyceride homeostasis (GO:0070328) 23 4 2.27 + 1.76 3.00E-01 1.00E00 acylglycerol homeostasis (GO:0055090) 23 4 2.27 + 1.76 3.00E-01 1.00E00 response to arsenic-containing substance (GO:0046685) 23 4 2.27 + 1.76 3.00E-01 1.00E00 positive regulation of alpha-beta T cell differentiation (GO:0046638) 46 8 4.55 + 1.76 1.47E-01 1.00E00 positive regulation of alcohol biosynthetic process (GO:1902932) 23 4 2.27 + 1.76 3.00E-01 1.00E00 hepaticobiliary system development (GO:0061008) 92 16 9.10 + 1.76 4.18E-02 5.54E-01 positive regulation of neuron apoptotic process (GO:0043525) 75 13 7.42 + 1.75 6.23E-02 7.03E-01 positive regulation of MAPK cascade (GO:0043410) 427 74 42.22 + 1.75 2.24E-05 1.45E-03 positive regulation of smooth muscle cell proliferation (GO:0048661) 104 18 10.28 + 1.75 3.68E-02 5.14E-01 regulation of membrane lipid distribution (GO:0097035) 52 9 5.14 + 1.75 1.16E-01 9.47E-01 lipid localization (GO:0010876) 243 42 24.03 + 1.75 1.57E-03 5.16E-02 negative regulation of ion transmembrane transport (GO:0034766) 81 14 8.01 + 1.75 6.84E-02 7.22E-01 positive regulation of NF-kappaB transcription factor activity (GO:0051092) 139 24 13.74 + 1.75 1.81E-02 3.23E-01 negative regulation of glial cell differentiation (GO:0045686) 29 5 2.87 + 1.74 2.27E-01 1.00E00 plasma lipoprotein particle organization (GO:0071827) 29 5 2.87 + 1.74 2.27E-01 1.00E00 positive regulation of T cell migration (GO:2000406) 29 5 2.87 + 1.74 2.27E-01 1.00E00 chemical synaptic transmission, postsynaptic (GO:0099565) 29 5 2.87 + 1.74 2.27E-01 1.00E00 positive regulation of filopodium assembly (GO:0051491) 29 5 2.87 + 1.74 2.27E-01 1.00E00 negative regulation of neuron death (GO:1901215) 203 35 20.07 + 1.74 3.98E-03 1.06E-01 regulation of neuron death (GO:1901214) 319 55 31.54 + 1.74 3.23E-04 1.43E-02 positive regulation of smooth muscle cell migration (GO:0014911) 58 10 5.73 + 1.74 1.31E-01 9.76E-01 regulation of extrinsic apoptotic signaling pathway (GO:2001236) 145 25 14.34 + 1.74 1.44E-02 2.74E-01 negative regulation of hydrolase activity (GO:0051346) 250 43 24.72 + 1.74 1.30E-03 4.46E-02 negative regulation of secretion (GO:0051048) 157 27 15.52 + 1.74 1.29E-02 2.55E-01 negative regulation of protein depolymerization (GO:1901880) 64 11 6.33 + 1.74 1.01E-01 8.80E-01 positive regulation of small molecule metabolic process (GO:0062013) 128 22 12.66 + 1.74 2.09E-02 3.55E-01 response to drug (GO:0042493) 169 29 16.71 + 1.74 8.28E-03 1.88E-01 antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) 35 6 3.46 + 1.73 2.65E-01 1.00E00 regulation of organic acid transport (GO:0032890) 70 12 6.92 + 1.73 8.05E-02 8.04E-01 regulation of protein kinase B signaling (GO:0051896) 140 24 13.84 + 1.73 1.85E-02 3.29E-01 homeostasis of number of cells within a tissue (GO:0048873) 35 6 3.46 + 1.73 2.65E-01 1.00E00 postsynaptic signal transduction (GO:0098926) 35 6 3.46 + 1.73 2.65E-01 1.00E00 peptidyl-tyrosine dephosphorylation (GO:0035335) 35 6 3.46 + 1.73 2.65E-01 1.00E00 positive regulation of epithelial cell migration (GO:0010634) 140 24 13.84 + 1.73 1.85E-02 3.29E-01 response to virus (GO:0009615) 216 37 21.36 + 1.73 3.67E-03 1.00E-01 regulation of amyloid precursor protein catabolic process (GO:1902991) 41 7 4.05 + 1.73 1.98E-01 1.00E00 heart valve morphogenesis (GO:0003179) 41 7 4.05 + 1.73 1.98E-01 1.00E00 negative regulation of protein-containing complex assembly (GO:0031333) 129 22 12.75 + 1.72 2.17E-02 3.63E-01 regulation of collagen metabolic process (GO:0010712) 47 8 4.65 + 1.72 1.53E-01 1.00E00 regulation of lymphocyte migration (GO:2000401) 53 9 5.24 + 1.72 1.22E-01 9.82E-01 positive regulation of secretion by cell (GO:1903532) 271 46 26.79 + 1.72 1.38E-03 4.67E-02 lymphocyte homeostasis (GO:0002260) 65 11 6.43 + 1.71 1.05E-01 8.99E-01 response to wounding (GO:0009611) 266 45 26.30 + 1.71 1.30E-03 4.46E-02 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043154) 71 12 7.02 + 1.71 8.41E-02 8.33E-01 positive regulation of secretion (GO:0051047) 290 49 28.67 + 1.71 1.01E-03 3.63E-02 sensory perception of pain (GO:0019233) 77 13 7.61 + 1.71 9.21E-02 8.55E-01 regulation of glucose transmembrane transport (GO:0010827) 77 13 7.61 + 1.71 9.21E-02 8.54E-01 carboxylic acid transport (GO:0046942) 160 27 15.82 + 1.71 1.38E-02 2.69E-01 neutral lipid metabolic process (GO:0006638) 83 14 8.21 + 1.71 7.26E-02 7.41E-01 positive regulation of exocytosis (GO:0045921) 83 14 8.21 + 1.71 7.26E-02 7.40E-01 positive regulation of JNK cascade (GO:0046330) 83 14 8.21 + 1.71 7.26E-02 7.40E-01 gliogenesis (GO:0042063) 208 35 20.57 + 1.70 6.25E-03 1.50E-01 cellular response to lipid (GO:0071396) 315 53 31.14 + 1.70 5.97E-04 2.40E-02 regulation of viral process (GO:0050792) 149 25 14.73 + 1.70 2.23E-02 3.70E-01 tissue homeostasis (GO:0001894) 173 29 17.10 + 1.70 1.25E-02 2.54E-01 cell surface receptor signaling pathway (GO:0007166) 1445 242 142.87 + 1.69 2.82E-14 8.90E-12 regulation of neuron apoptotic process (GO:0043523) 227 38 22.44 + 1.69 4.54E-03 1.16E-01 metal ion homeostasis (GO:0055065) 508 85 50.23 + 1.69 1.43E-05 1.01E-03 cerebral cortex regionalization (GO:0021796) 6 1 .59 + 1.69 4.83E-01 1.00E00 melanosome assembly (GO:1903232) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of hydrogen peroxide-induced neuron death (GO:1903208) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of hydrogen peroxide-induced neuron death (GO:1903207) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of forebrain neuron differentiation (GO:2000977) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of digestive system process (GO:0060457) 12 2 1.19 + 1.69 3.63E-01 1.00E00 positive regulation of digestive system process (GO:0060456) 12 2 1.19 + 1.69 3.63E-01 1.00E00 lung growth (GO:0060437) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of sterol import (GO:2000909) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of vitamin metabolic process (GO:0046137) 6 1 .59 + 1.69 4.83E-01 1.00E00 purine ribonucleoside catabolic process (GO:0046130) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of toll-like receptor 4 signaling pathway (GO:0034145) 12 2 1.19 + 1.69 3.63E-01 1.00E00 negative regulation of toll-like receptor 2 signaling pathway (GO:0034136) 6 1 .59 + 1.69 4.83E-01 1.00E00 tolerance induction to self antigen (GO:0002513) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of monocyte differentiation (GO:0045656) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of megakaryocyte differentiation (GO:0045652) 18 3 1.78 + 1.69 4.30E-01 1.00E00 central nervous system maturation (GO:0021626) 6 1 .59 + 1.69 4.83E-01 1.00E00 egg activation (GO:0007343) 6 1 .59 + 1.69 4.83E-01 1.00E00 penetration of zona pellucida (GO:0007341) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of glucocorticoid secretion (GO:2000849) 6 1 .59 + 1.69 4.83E-01 1.00E00 glomerular epithelial cell differentiation (GO:0072311) 12 2 1.19 + 1.69 3.63E-01 1.00E00 regulation of axon guidance (GO:1902667) 12 2 1.19 + 1.69 3.63E-01 1.00E00 positive regulation of interferon-gamma-mediated signaling pathway (GO:0060335) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of response to interferon-gamma (GO:0060332) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of synaptic vesicle clustering (GO:2000809) 6 1 .59 + 1.69 4.83E-01 1.00E00 IMP metabolic process (GO:0046040) 12 2 1.19 + 1.69 3.63E-01 1.00E00 negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) 6 1 .59 + 1.69 4.83E-01 1.00E00 drug transmembrane transport (GO:0006855) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of activated T cell proliferation (GO:0046007) 12 2 1.19 + 1.69 3.63E-01 1.00E00 regulation of caveolin-mediated endocytosis (GO:2001286) 6 1 .59 + 1.69 4.83E-01 1.00E00 mammary gland epithelial cell proliferation (GO:0033598) 12 2 1.19 + 1.69 3.63E-01 1.00E00 N-acetylneuraminate catabolic process (GO:0019262) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of osteoclast development (GO:2001206) 6 1 .59 + 1.69 4.83E-01 1.00E00 lactate biosynthetic process (GO:0019249) 6 1 .59 + 1.69 4.83E-01 1.00E00 dentate gyrus development (GO:0021542) 12 2 1.19 + 1.69 3.63E-01 1.00E00 metanephric nephron tubule morphogenesis (GO:0072282) 6 1 .59 + 1.69 4.83E-01 1.00E00 blood vessel maturation (GO:0001955) 6 1 .59 + 1.69 4.83E-01 1.00E00 ventral spinal cord interneuron differentiation (GO:0021514) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of cilium movement involved in cell motility (GO:0060295) 12 2 1.19 + 1.69 3.63E-01 1.00E00 long-term synaptic potentiation (GO:0060291) 42 7 4.15 + 1.69 2.05E-01 1.00E00 B-1 B cell differentiation (GO:0001923) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of transcription of Notch receptor target (GO:0007221) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of respiratory burst (GO:0060263) 12 2 1.19 + 1.69 3.63E-01 1.00E00 metanephric glomerulus development (GO:0072224) 6 1 .59 + 1.69 4.83E-01 1.00E00 cellular response to aldehyde (GO:0110096) 12 2 1.19 + 1.69 3.63E-01 1.00E00 B cell selection (GO:0002339) 6 1 .59 + 1.69 4.83E-01 1.00E00 pre-B cell differentiation (GO:0002329) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of ATP biosynthetic process (GO:2001171) 12 2 1.19 + 1.69 3.63E-01 1.00E00 B cell lineage commitment (GO:0002326) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of ATP biosynthetic process (GO:2001169) 18 3 1.78 + 1.69 4.30E-01 1.00E00 gas homeostasis (GO:0033483) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of lipase activity (GO:0060193) 48 8 4.75 + 1.69 1.60E-01 1.00E00 limb bud formation (GO:0060174) 6 1 .59 + 1.69 4.83E-01 1.00E00 phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) 6 1 .59 + 1.69 4.83E-01 1.00E00 glomerular visceral epithelial cell differentiation (GO:0072112) 12 2 1.19 + 1.69 3.63E-01 1.00E00 regulation of smooth muscle cell chemotaxis (GO:0071671) 6 1 .59 + 1.69 4.83E-01 1.00E00 monoacylglycerol biosynthetic process (GO:0006640) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of monocyte chemotactic protein-1 production (GO:0071639) 12 2 1.19 + 1.69 3.63E-01 1.00E00 regulation of meiotic cell cycle phase transition (GO:1901993) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of skeletal muscle cell differentiation (GO:2001016) 6 1 .59 + 1.69 4.83E-01 1.00E00 spindle assembly involved in female meiosis (GO:0007056) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of CD4-positive, alpha-beta T cell proliferation (GO:2000561) 12 2 1.19 + 1.69 3.63E-01 1.00E00 mesodermal cell fate commitment (GO:0001710) 6 1 .59 + 1.69 4.83E-01 1.00E00 endoderm formation (GO:0001706) 24 4 2.37 + 1.69 3.12E-01 1.00E00 negative regulation by host of viral genome replication (GO:0044828) 6 1 .59 + 1.69 4.83E-01 1.00E00 pericardium development (GO:0060039) 24 4 2.37 + 1.69 3.12E-01 1.00E00 regulation of cellular pH reduction (GO:0032847) 6 1 .59 + 1.69 4.83E-01 1.00E00 multi-organism membrane organization (GO:0044803) 6 1 .59 + 1.69 4.83E-01 1.00E00 reflex (GO:0060004) 18 3 1.78 + 1.69 4.30E-01 1.00E00 amino-acid betaine metabolic process (GO:0006577) 12 2 1.19 + 1.69 3.63E-01 1.00E00 lacrimal gland development (GO:0032808) 6 1 .59 + 1.69 4.83E-01 1.00E00 nuclear cell cycle DNA replication initiation (GO:1902315) 6 1 .59 + 1.69 4.83E-01 1.00E00 histone H3-K27 demethylation (GO:0071557) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of transmission of nerve impulse (GO:0051971) 6 1 .59 + 1.69 4.83E-01 1.00E00 cellular response to dexamethasone stimulus (GO:0071549) 18 3 1.78 + 1.69 4.30E-01 1.00E00 C-terminal protein lipidation (GO:0006501) 6 1 .59 + 1.69 4.83E-01 1.00E00 bile acid secretion (GO:0032782) 6 1 .59 + 1.69 4.83E-01 1.00E00 cell cycle DNA replication initiation (GO:1902292) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of T cell extravasation (GO:2000407) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage (GO:1902230) 24 4 2.37 + 1.69 3.12E-01 1.00E00 negative regulation of interleukin-4 production (GO:0032713) 6 1 .59 + 1.69 4.83E-01 1.00E00 cellular response to laminar fluid shear stress (GO:0071499) 6 1 .59 + 1.69 4.83E-01 1.00E00 cellular response to UV-A (GO:0071492) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of interleukin-2 production (GO:0032703) 24 4 2.37 + 1.69 3.12E-01 1.00E00 netrin-activated signaling pathway (GO:0038007) 6 1 .59 + 1.69 4.83E-01 1.00E00 brain renin-angiotensin system (GO:0002035) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of sodium ion transport (GO:0002028) 72 12 7.12 + 1.69 1.21E-01 9.74E-01 regulation of synapse structural plasticity (GO:0051823) 6 1 .59 + 1.69 4.83E-01 1.00E00 bone maturation (GO:0070977) 18 3 1.78 + 1.69 4.30E-01 1.00E00 regulation of ovarian follicle development (GO:2000354) 6 1 .59 + 1.69 4.83E-01 1.00E00 cellular response to reactive nitrogen species (GO:1902170) 12 2 1.19 + 1.69 3.63E-01 1.00E00 cellular response to testosterone stimulus (GO:0071394) 6 1 .59 + 1.69 4.83E-01 1.00E00 chromatin silencing at telomere (GO:0006348) 6 1 .59 + 1.69 4.83E-01 1.00E00 cellular response to ethanol (GO:0071361) 6 1 .59 + 1.69 4.83E-01 1.00E00 nucleotide transmembrane transport (GO:1901679) 12 2 1.19 + 1.69 3.63E-01 1.00E00 positive thymic T cell selection (GO:0045059) 12 2 1.19 + 1.69 3.63E-01 1.00E00 dopamine uptake (GO:0090494) 6 1 .59 + 1.69 4.83E-01 1.00E00 catecholamine uptake (GO:0090493) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of glycogen metabolic process (GO:0070874) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of glycogen metabolic process (GO:0070873) 30 5 2.97 + 1.69 2.40E-01 1.00E00 aggresome assembly (GO:0070842) 6 1 .59 + 1.69 4.83E-01 1.00E00 dehydroascorbic acid transport (GO:0070837) 6 1 .59 + 1.69 4.83E-01 1.00E00 cellular response to salt (GO:1902075) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of cell projection size (GO:0032536) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of anoikis (GO:2000209) 18 3 1.78 + 1.69 4.30E-01 1.00E00 L-arginine transport (GO:1902023) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of cilium-dependent cell motility (GO:1902019) 12 2 1.19 + 1.69 3.63E-01 1.00E00 cellular response to magnesium ion (GO:0071286) 6 1 .59 + 1.69 4.83E-01 1.00E00 potassium ion import across plasma membrane (GO:1990573) 30 5 2.97 + 1.69 2.40E-01 1.00E00 cellular response to peptidoglycan (GO:0071224) 6 1 .59 + 1.69 4.83E-01 1.00E00 fatty acid derivative biosynthetic process (GO:1901570) 18 3 1.78 + 1.69 4.30E-01 1.00E00 serotonin uptake (GO:0051610) 6 1 .59 + 1.69 4.83E-01 1.00E00 phagosome acidification (GO:0090383) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of protein targeting to membrane (GO:0090315) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of Rab protein signal transduction (GO:0032483) 6 1 .59 + 1.69 4.83E-01 1.00E00 trans-synaptic signaling by endocannabinoid (GO:0099542) 6 1 .59 + 1.69 4.83E-01 1.00E00 trans-synaptic signaling by lipid (GO:0099541) 6 1 .59 + 1.69 4.83E-01 1.00E00 synaptic vesicle endosomal processing (GO:0099532) 12 2 1.19 + 1.69 3.63E-01 1.00E00 polar body extrusion after meiotic divisions (GO:0040038) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of neurotransmitter uptake (GO:0051580) 12 2 1.19 + 1.69 3.63E-01 1.00E00 isocitrate metabolic process (GO:0006102) 6 1 .59 + 1.69 4.83E-01 1.00E00 response to interleukin-12 (GO:0070671) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of release of cytochrome c from mitochondria (GO:0090201) 18 3 1.78 + 1.69 4.30E-01 1.00E00 regulation of phospholipid biosynthetic process (GO:0071071) 18 3 1.78 + 1.69 4.30E-01 1.00E00 negative regulation of cytosolic calcium ion concentration (GO:0051481) 12 2 1.19 + 1.69 3.63E-01 1.00E00 double-strand break repair via break-induced replication (GO:0000727) 12 2 1.19 + 1.69 3.63E-01 1.00E00 dendritic transport of messenger ribonucleoprotein complex (GO:0098963) 6 1 .59 + 1.69 4.83E-01 1.00E00 dendritic transport of ribonucleoprotein complex (GO:0098961) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of cell fate specification (GO:0009996) 6 1 .59 + 1.69 4.83E-01 1.00E00 intracellular pH elevation (GO:0051454) 6 1 .59 + 1.69 4.83E-01 1.00E00 fructose 6-phosphate metabolic process (GO:0006002) 12 2 1.19 + 1.69 3.63E-01 1.00E00 regulation of pancreatic juice secretion (GO:0090186) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of sphingolipid biosynthetic process (GO:0090155) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of sphingolipid biosynthetic process (GO:0090153) 12 2 1.19 + 1.69 3.63E-01 1.00E00 negative regulation of skeletal muscle tissue development (GO:0048642) 6 1 .59 + 1.69 4.83E-01 1.00E00 cochlea morphogenesis (GO:0090103) 18 3 1.78 + 1.69 4.30E-01 1.00E00 cholesterol import (GO:0070508) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of gonadotropin secretion (GO:0032276) 6 1 .59 + 1.69 4.83E-01 1.00E00 purine nucleotide salvage (GO:0032261) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of inflammatory response to wounding (GO:0106014) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of synaptic transmission, cholinergic (GO:0032224) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of hydrogen peroxide-mediated programmed cell death (GO:1901298) 12 2 1.19 + 1.69 3.63E-01 1.00E00 negative regulation of lyase activity (GO:0051350) 12 2 1.19 + 1.69 3.63E-01 1.00E00 folate transmembrane transport (GO:0098838) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of presynapse assembly (GO:1905606) 24 4 2.37 + 1.69 3.12E-01 1.00E00 interleukin-1-mediated signaling pathway (GO:0070498) 18 3 1.78 + 1.69 4.30E-01 1.00E00 regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901213) 6 1 .59 + 1.69 4.83E-01 1.00E00 intestinal absorption (GO:0050892) 18 3 1.78 + 1.69 4.30E-01 1.00E00 embryonic digestive tract development (GO:0048566) 24 4 2.37 + 1.69 3.12E-01 1.00E00 activation of protein kinase B activity (GO:0032148) 18 3 1.78 + 1.69 4.30E-01 1.00E00 regulation of DNA-templated transcription in response to stress (GO:0043620) 48 8 4.75 + 1.69 1.60E-01 1.00E00 protein destabilization (GO:0031648) 48 8 4.75 + 1.69 1.60E-01 1.00E00 calcium ion import across plasma membrane (GO:0098703) 12 2 1.19 + 1.69 3.63E-01 1.00E00 enteric nervous system development (GO:0048484) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of focal adhesion disassembly (GO:0120183) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of focal adhesion disassembly (GO:0120182) 6 1 .59 + 1.69 4.83E-01 1.00E00 tendon development (GO:0035989) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of insulin-like growth factor receptor signaling pathway (GO:0043567) 18 3 1.78 + 1.69 4.30E-01 1.00E00 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (GO:0031585) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of blood vessel endothelial cell migration (GO:0043537) 30 5 2.97 + 1.69 2.40E-01 1.00E00 actin cytoskeleton reorganization (GO:0031532) 66 11 6.53 + 1.69 1.09E-01 9.06E-01 negative regulation of retinoic acid receptor signaling pathway (GO:0048387) 6 1 .59 + 1.69 4.83E-01 1.00E00 chondroitin sulfate proteoglycan biosynthetic process (GO:0050650) 18 3 1.78 + 1.69 4.30E-01 1.00E00 negative regulation of lymphocyte apoptotic process (GO:0070229) 36 6 3.56 + 1.69 2.70E-01 1.00E00 protein auto-ADP-ribosylation (GO:0070213) 12 2 1.19 + 1.69 3.63E-01 1.00E00 intracellular distribution of mitochondria (GO:0048312) 12 2 1.19 + 1.69 3.63E-01 1.00E00 regulation of cellular carbohydrate catabolic process (GO:0043471) 12 2 1.19 + 1.69 3.63E-01 1.00E00 histone H3-K27 trimethylation (GO:0098532) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of lipoprotein lipase activity (GO:0051006) 6 1 .59 + 1.69 4.83E-01 1.00E00 kynurenine metabolic process (GO:0070189) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of isotype switching to IgA isotypes (GO:0048298) 6 1 .59 + 1.69 4.83E-01 1.00E00 D-amino acid transport (GO:0042940) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of glutamate receptor signaling pathway (GO:1900449) 6 1 .59 + 1.69 4.83E-01 1.00E00 midbrain-hindbrain boundary development (GO:0030917) 6 1 .59 + 1.69 4.83E-01 1.00E00 otic vesicle formation (GO:0030916) 6 1 .59 + 1.69 4.83E-01 1.00E00 nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289) 12 2 1.19 + 1.69 3.63E-01 1.00E00 regulation of CD8-positive, alpha-beta T cell differentiation (GO:0043376) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of protein localization to cell cortex (GO:1904778) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of lysosomal protein catabolic process (GO:1905165) 6 1 .59 + 1.69 4.83E-01 1.00E00 oligosaccharide catabolic process (GO:0009313) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of metalloendopeptidase activity (GO:1904683) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of long-term synaptic potentiation (GO:1900271) 48 8 4.75 + 1.69 1.60E-01 1.00E00 insulin-like growth factor receptor signaling pathway (GO:0048009) 12 2 1.19 + 1.69 3.63E-01 1.00E00 negative regulation of NLRP3 inflammasome complex assembly (GO:1900226) 6 1 .59 + 1.69 4.83E-01 1.00E00 cellular response to macrophage colony-stimulating factor stimulus (GO:0036006) 6 1 .59 + 1.69 4.83E-01 1.00E00 response to macrophage colony-stimulating factor (GO:0036005) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of membrane lipid metabolic process (GO:1905038) 12 2 1.19 + 1.69 3.63E-01 1.00E00 regulation of epithelial to mesenchymal transition involved in endocardial cushion formation (GO:1905005) 6 1 .59 + 1.69 4.83E-01 1.00E00 cellular phosphate ion homeostasis (GO:0030643) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of receptor binding (GO:1900121) 12 2 1.19 + 1.69 3.63E-01 1.00E00 regulation of response to osmotic stress (GO:0047484) 12 2 1.19 + 1.69 3.63E-01 1.00E00 folic acid transport (GO:0015884) 6 1 .59 + 1.69 4.83E-01 1.00E00 choline transport (GO:0015871) 6 1 .59 + 1.69 4.83E-01 1.00E00 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay (GO:0031086) 6 1 .59 + 1.69 4.83E-01 1.00E00 T cell homeostasis (GO:0043029) 36 6 3.56 + 1.69 2.70E-01 1.00E00 histone-threonine phosphorylation (GO:0035405) 6 1 .59 + 1.69 4.83E-01 1.00E00 deoxyribonucleoside monophosphate catabolic process (GO:0009159) 12 2 1.19 + 1.69 3.63E-01 1.00E00 G protein-coupled receptor signaling pathway involved in heart process (GO:0086103) 6 1 .59 + 1.69 4.83E-01 1.00E00 retinol metabolic process (GO:0042572) 12 2 1.19 + 1.69 3.63E-01 1.00E00 calcitonin family receptor signaling pathway (GO:0097646) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of phosphate transport (GO:0010966) 6 1 .59 + 1.69 4.83E-01 1.00E00 autophagosome membrane docking (GO:0016240) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of substrate adhesion-dependent cell spreading (GO:1900025) 12 2 1.19 + 1.69 3.63E-01 1.00E00 sterol import (GO:0035376) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035360) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of receptor clustering (GO:1903909) 18 3 1.78 + 1.69 4.30E-01 1.00E00 quinolinate metabolic process (GO:0046874) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of triglyceride catabolic process (GO:0010898) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of sequestering of triglyceride (GO:0010890) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of gastro-intestinal system smooth muscle contraction (GO:1904304) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of keratinocyte proliferation (GO:0010839) 12 2 1.19 + 1.69 3.63E-01 1.00E00 regulation of keratinocyte proliferation (GO:0010837) 24 4 2.37 + 1.69 3.12E-01 1.00E00 bradykinin catabolic process (GO:0010815) 6 1 .59 + 1.69 4.83E-01 1.00E00 sympathetic ganglion development (GO:0061549) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of spontaneous synaptic transmission (GO:0150003) 6 1 .59 + 1.69 4.83E-01 1.00E00 water-soluble vitamin biosynthetic process (GO:0042364) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of macrophage chemotaxis (GO:0010760) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of hydrogen peroxide metabolic process (GO:0010727) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of extracellular matrix disassembly (GO:0010715) 12 2 1.19 + 1.69 3.63E-01 1.00E00 kidney vasculature morphogenesis (GO:0061439) 6 1 .59 + 1.69 4.83E-01 1.00E00 renal system vasculature morphogenesis (GO:0061438) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia (GO:0061419) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of I-kappaB phosphorylation (GO:1903721) 6 1 .59 + 1.69 4.83E-01 1.00E00 forelimb morphogenesis (GO:0035136) 24 4 2.37 + 1.69 3.12E-01 1.00E00 tetrahydrofolate biosynthetic process (GO:0046654) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of microglial cell migration (GO:1904141) 6 1 .59 + 1.69 4.83E-01 1.00E00 inhibition of cysteine-type endopeptidase activity (GO:0097340) 6 1 .59 + 1.69 4.83E-01 1.00E00 muscle cell apoptotic process (GO:0010657) 6 1 .59 + 1.69 4.83E-01 1.00E00 extracellular matrix disassembly (GO:0022617) 18 3 1.78 + 1.69 4.30E-01 1.00E00 platelet formation (GO:0030220) 18 3 1.78 + 1.69 4.30E-01 1.00E00 heparin biosynthetic process (GO:0030210) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of triglyceride lipase activity (GO:0061365) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of sprouting angiogenesis (GO:1903671) 12 2 1.19 + 1.69 3.63E-01 1.00E00 renal filtration cell differentiation (GO:0061318) 12 2 1.19 + 1.69 3.63E-01 1.00E00 cell surface receptor signaling pathway involved in heart development (GO:0061311) 18 3 1.78 + 1.69 4.30E-01 1.00E00 arterial endothelial cell differentiation (GO:0060842) 6 1 .59 + 1.69 4.83E-01 1.00E00 miRNA catabolic process (GO:0010587) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of platelet activation (GO:0010572) 6 1 .59 + 1.69 4.83E-01 1.00E00 myotube differentiation involved in skeletal muscle regeneration (GO:0014908) 6 1 .59 + 1.69 4.83E-01 1.00E00 response to ischemia (GO:0002931) 36 6 3.56 + 1.69 2.70E-01 1.00E00 regulation of activation of Janus kinase activity (GO:0010533) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of extracellular exosome assembly (GO:1903551) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of membrane tubulation (GO:1903525) 6 1 .59 + 1.69 4.83E-01 1.00E00 mammary duct terminal end bud growth (GO:0060763) 6 1 .59 + 1.69 4.83E-01 1.00E00 glyoxylate metabolic process (GO:0046487) 6 1 .59 + 1.69 4.83E-01 1.00E00 chorionic trophoblast cell differentiation (GO:0060718) 6 1 .59 + 1.69 4.83E-01 1.00E00 muscle atrophy (GO:0014889) 6 1 .59 + 1.69 4.83E-01 1.00E00 response to muscle activity (GO:0014850) 12 2 1.19 + 1.69 3.63E-01 1.00E00 regulation of immunoglobulin mediated immune response (GO:0002889) 60 10 5.93 + 1.69 1.38E-01 1.00E00 positive regulation of natural killer cell mediated immune response to tumor cell (GO:0002857) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of cell fate commitment (GO:0010454) 12 2 1.19 + 1.69 3.63E-01 1.00E00 presynaptic membrane assembly (GO:0097105) 6 1 .59 + 1.69 4.83E-01 1.00E00 response to acidic pH (GO:0010447) 18 3 1.78 + 1.69 4.30E-01 1.00E00 negative regulation of immune response to tumor cell (GO:0002838) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of response to tumor cell (GO:0002835) 6 1 .59 + 1.69 4.83E-01 1.00E00 positive regulation of circadian sleep/wake cycle, sleep (GO:0045938) 6 1 .59 + 1.69 4.83E-01 1.00E00 adenohypophysis development (GO:0021984) 6 1 .59 + 1.69 4.83E-01 1.00E00 NAD metabolic process (GO:0019674) 18 3 1.78 + 1.69 4.30E-01 1.00E00 regulation of cerebellar granule cell precursor proliferation (GO:0021936) 6 1 .59 + 1.69 4.83E-01 1.00E00 epithelial cell proliferation involved in salivary gland morphogenesis (GO:0060664) 6 1 .59 + 1.69 4.83E-01 1.00E00 mitotic DNA replication initiation (GO:1902975) 6 1 .59 + 1.69 4.83E-01 1.00E00 high-density lipoprotein particle clearance (GO:0034384) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of cholesterol import (GO:0060620) 6 1 .59 + 1.69 4.83E-01 1.00E00 synaptic vesicle clustering (GO:0097091) 6 1 .59 + 1.69 4.83E-01 1.00E00 presynaptic membrane organization (GO:0097090) 6 1 .59 + 1.69 4.83E-01 1.00E00 triglyceride-rich lipoprotein particle remodeling (GO:0034370) 6 1 .59 + 1.69 4.83E-01 1.00E00 diacylglycerol metabolic process (GO:0046339) 24 4 2.37 + 1.69 3.12E-01 1.00E00 phosphatidylethanolamine metabolic process (GO:0046337) 18 3 1.78 + 1.69 4.30E-01 1.00E00 vascular associated smooth muscle cell development (GO:0097084) 12 2 1.19 + 1.69 3.63E-01 1.00E00 lateral sprouting from an epithelium (GO:0060601) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of fatty acid oxidation (GO:0046322) 12 2 1.19 + 1.69 3.63E-01 1.00E00 immune response-inhibiting signal transduction (GO:0002765) 6 1 .59 + 1.69 4.83E-01 1.00E00 cytoplasmic pattern recognition receptor signaling pathway (GO:0002753) 18 3 1.78 + 1.69 4.30E-01 1.00E00 positive regulation of myeloid dendritic cell cytokine production (GO:0002735) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of myeloid dendritic cell cytokine production (GO:0002733) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of phospholipid translocation (GO:0061091) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of natural killer cell cytokine production (GO:0002727) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of B cell mediated immunity (GO:0002712) 60 10 5.93 + 1.69 1.38E-01 1.00E00 negative regulation of membrane potential (GO:0045837) 18 3 1.78 + 1.69 4.30E-01 1.00E00 vascular wound healing (GO:0061042) 6 1 .59 + 1.69 4.83E-01 1.00E00 pyramidal neuron development (GO:0021860) 12 2 1.19 + 1.69 3.63E-01 1.00E00 positive regulation of hexokinase activity (GO:1903301) 6 1 .59 + 1.69 4.83E-01 1.00E00 layer formation in cerebral cortex (GO:0021819) 12 2 1.19 + 1.69 3.63E-01 1.00E00 mammary gland formation (GO:0060592) 6 1 .59 + 1.69 4.83E-01 1.00E00 pulmonary valve development (GO:0003177) 18 3 1.78 + 1.69 4.30E-01 1.00E00 cerebral cortex tangential migration (GO:0021800) 6 1 .59 + 1.69 4.83E-01 1.00E00 purine-containing compound transmembrane transport (GO:0072530) 12 2 1.19 + 1.69 3.63E-01 1.00E00 cellular trivalent inorganic anion homeostasis (GO:0072502) 6 1 .59 + 1.69 4.83E-01 1.00E00 type II pneumocyte differentiation (GO:0060510) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of GTPase activity (GO:0034260) 30 5 2.97 + 1.69 2.40E-01 1.00E00 positive regulation of epithelial cell proliferation involved in lung morphogenesis (GO:0060501) 6 1 .59 + 1.69 4.83E-01 1.00E00 negative regulation of syncytium formation by plasma membrane fusion (GO:0034242) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of macrophage fusion (GO:0034239) 6 1 .59 + 1.69 4.83E-01 1.00E00 regulation of fatty acid metabolic process (GO:0019217) 78 13 7.71 + 1.69 9.45E-02 8.71E-01 regulation of metal ion transport (GO:0010959) 234 39 23.14 + 1.69 3.75E-03 1.02E-01 regulation of calcium ion transport into cytosol (GO:0010522) 90 15 8.90 + 1.69 8.35E-02 8.28E-01 response to lipid (GO:0033993) 492 82 48.64 + 1.69 2.80E-05 1.78E-03 biological adhesion (GO:0022610) 650 108 64.27 + 1.68 1.29E-06 1.23E-04 regulation of cell adhesion (GO:0030155) 650 108 64.27 + 1.68 1.29E-06 1.23E-04 multicellular organismal homeostasis (GO:0048871) 271 45 26.79 + 1.68 1.96E-03 6.09E-02 positive regulation of response to biotic stimulus (GO:0002833) 139 23 13.74 + 1.67 2.64E-02 4.16E-01 regulation of regulated secretory pathway (GO:1903305) 139 23 13.74 + 1.67 2.64E-02 4.15E-01 positive regulation of response to stimulus (GO:0048584) 1777 294 175.69 + 1.67 8.37E-17 4.23E-14 membrane organization (GO:0061024) 611 101 60.41 + 1.67 3.37E-06 2.88E-04 positive regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043123) 115 19 11.37 + 1.67 4.68E-02 5.79E-01 cell adhesion (GO:0007155) 642 106 63.48 + 1.67 2.13E-06 1.90E-04 regulation of endocytosis (GO:0030100) 206 34 20.37 + 1.67 8.42E-03 1.90E-01 actomyosin structure organization (GO:0031032) 91 15 9.00 + 1.67 8.50E-02 8.40E-01 regulation of T cell mediated immunity (GO:0002709) 85 14 8.40 + 1.67 7.78E-02 7.87E-01 regulation of lymphocyte mediated immunity (GO:0002706) 170 28 16.81 + 1.67 1.67E-02 3.07E-01 glial cell differentiation (GO:0010001) 164 27 16.21 + 1.67 2.09E-02 3.55E-01 transition metal ion transport (GO:0000041) 79 13 7.81 + 1.66 9.71E-02 8.57E-01 regulation of ATP metabolic process (GO:1903578) 79 13 7.81 + 1.66 9.71E-02 8.56E-01 intrinsic apoptotic signaling pathway in response to DNA damage (GO:0008630) 73 12 7.22 + 1.66 1.24E-01 9.89E-01 heart contraction (GO:0060047) 67 11 6.62 + 1.66 1.13E-01 9.33E-01 cellular glucose homeostasis (GO:0001678) 61 10 6.03 + 1.66 1.42E-01 1.00E00 anatomical structure maturation (GO:0071695) 177 29 17.50 + 1.66 1.40E-02 2.69E-01 carbohydrate derivative catabolic process (GO:1901136) 116 19 11.47 + 1.66 4.80E-02 5.92E-01 negative regulation of immune response (GO:0050777) 171 28 16.91 + 1.66 1.71E-02 3.14E-01 triglyceride metabolic process (GO:0006641) 55 9 5.44 + 1.66 1.83E-01 1.00E00 myeloid cell activation involved in immune response (GO:0002275) 49 8 4.84 + 1.65 1.67E-01 1.00E00 positive regulation of cellular carbohydrate metabolic process (GO:0010676) 49 8 4.84 + 1.65 1.67E-01 1.00E00 labyrinthine layer development (GO:0060711) 49 8 4.84 + 1.65 1.67E-01 1.00E00 actin polymerization or depolymerization (GO:0008154) 49 8 4.84 + 1.65 1.67E-01 1.00E00 positive regulation of lipid localization (GO:1905954) 92 15 9.10 + 1.65 8.67E-02 8.22E-01 negative regulation of G protein-coupled receptor signaling pathway (GO:0045744) 43 7 4.25 + 1.65 2.12E-01 1.00E00 regulation of extracellular matrix organization (GO:1903053) 43 7 4.25 + 1.65 2.12E-01 1.00E00 negative regulation of cold-induced thermogenesis (GO:0120163) 43 7 4.25 + 1.65 2.12E-01 1.00E00 cellular response to virus (GO:0098586) 43 7 4.25 + 1.65 2.12E-01 1.00E00 receptor metabolic process (GO:0043112) 86 14 8.50 + 1.65 1.11E-01 9.18E-01 response to hydrogen peroxide (GO:0042542) 86 14 8.50 + 1.65 1.11E-01 9.18E-01 positive regulation of epithelial to mesenchymal transition (GO:0010718) 43 7 4.25 + 1.65 2.12E-01 1.00E00 negative regulation of endothelial cell migration (GO:0010596) 43 7 4.25 + 1.65 2.12E-01 1.00E00 regulation of cell migration (GO:0030334) 812 132 80.28 + 1.64 2.15E-07 2.65E-05 regulation of biomineral tissue development (GO:0070167) 80 13 7.91 + 1.64 1.00E-01 8.70E-01 regulation of amine transport (GO:0051952) 74 12 7.32 + 1.64 1.26E-01 9.53E-01 negative regulation of epithelial cell differentiation (GO:0030857) 37 6 3.66 + 1.64 2.77E-01 1.00E00 regulation of fatty acid biosynthetic process (GO:0042304) 37 6 3.66 + 1.64 2.77E-01 1.00E00 glial cell migration (GO:0008347) 37 6 3.66 + 1.64 2.77E-01 1.00E00 glycerolipid catabolic process (GO:0046503) 37 6 3.66 + 1.64 2.77E-01 1.00E00 muscle contraction (GO:0006936) 136 22 13.45 + 1.64 3.56E-02 4.99E-01 positive regulation of phosphatidylinositol 3-kinase signaling (GO:0014068) 68 11 6.72 + 1.64 1.62E-01 1.00E00 regulation of insulin receptor signaling pathway (GO:0046626) 68 11 6.72 + 1.64 1.62E-01 1.00E00 regulation of hydrogen peroxide-induced cell death (GO:1903205) 31 5 3.07 + 1.63 3.72E-01 1.00E00 regulation of oxidative stress-induced neuron death (GO:1903203) 31 5 3.07 + 1.63 3.72E-01 1.00E00 ATP biosynthetic process (GO:0006754) 31 5 3.07 + 1.63 3.72E-01 1.00E00 negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) 31 5 3.07 + 1.63 3.72E-01 1.00E00 extrinsic apoptotic signaling pathway via death domain receptors (GO:0008625) 31 5 3.07 + 1.63 3.72E-01 1.00E00 positive regulation of steroid metabolic process (GO:0045940) 31 5 3.07 + 1.63 3.72E-01 1.00E00 inorganic ion homeostasis (GO:0098771) 583 94 57.64 + 1.63 1.91E-05 1.25E-03 positive regulation of multicellular organismal process (GO:0051240) 1280 206 126.56 + 1.63 1.04E-10 1.97E-08 positive regulation of DNA-binding transcription factor activity (GO:0051091) 230 37 22.74 + 1.63 9.13E-03 2.02E-01 oligodendrocyte differentiation (GO:0048709) 56 9 5.54 + 1.63 1.87E-01 1.00E00 negative regulation of response to cytokine stimulus (GO:0060761) 56 9 5.54 + 1.63 1.87E-01 1.00E00 response to inorganic substance (GO:0010035) 361 58 35.69 + 1.62 9.47E-04 3.45E-02 acylglycerol metabolic process (GO:0006639) 81 13 8.01 + 1.62 1.03E-01 8.92E-01 defense response to symbiont (GO:0140546) 162 26 16.02 + 1.62 2.81E-02 4.38E-01 defense response to virus (GO:0051607) 162 26 16.02 + 1.62 2.81E-02 4.38E-01 salivary gland morphogenesis (GO:0007435) 25 4 2.47 + 1.62 3.26E-01 1.00E00 negative regulation of protein localization to plasma membrane (GO:1903077) 25 4 2.47 + 1.62 3.26E-01 1.00E00 water-soluble vitamin metabolic process (GO:0006767) 25 4 2.47 + 1.62 3.26E-01 1.00E00 pharyngeal system development (GO:0060037) 25 4 2.47 + 1.62 3.26E-01 1.00E00 negative regulation of calcium ion transport (GO:0051926) 50 8 4.94 + 1.62 2.43E-01 1.00E00 regulation of nitric-oxide synthase biosynthetic process (GO:0051769) 25 4 2.47 + 1.62 3.26E-01 1.00E00 positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) 25 4 2.47 + 1.62 3.26E-01 1.00E00 regulation of vesicle fusion (GO:0031338) 25 4 2.47 + 1.62 3.26E-01 1.00E00 positive regulation of long-term synaptic potentiation (GO:1900273) 25 4 2.47 + 1.62 3.26E-01 1.00E00 peptide catabolic process (GO:0043171) 25 4 2.47 + 1.62 3.26E-01 1.00E00 positive regulation of cellular response to insulin stimulus (GO:1900078) 25 4 2.47 + 1.62 3.26E-01 1.00E00 negative regulation of alpha-beta T cell differentiation (GO:0046639) 25 4 2.47 + 1.62 3.26E-01 1.00E00 regulation of carbohydrate biosynthetic process (GO:0043255) 94 15 9.29 + 1.61 9.11E-02 8.51E-01 positive regulation of endothelial cell migration (GO:0010595) 94 15 9.29 + 1.61 9.11E-02 8.51E-01 regulation of potassium ion transmembrane transport (GO:1901379) 69 11 6.82 + 1.61 1.65E-01 1.00E00 cholesterol homeostasis (GO:0042632) 69 11 6.82 + 1.61 1.65E-01 1.00E00 positive regulation of carbohydrate metabolic process (GO:0045913) 69 11 6.82 + 1.61 1.65E-01 1.00E00 cellular metal ion homeostasis (GO:0006875) 452 72 44.69 + 1.61 2.53E-04 1.17E-02 adenylate cyclase-activating G protein-coupled receptor signaling pathway (GO:0007189) 88 14 8.70 + 1.61 1.15E-01 9.37E-01 regulation of type I interferon production (GO:0032479) 88 14 8.70 + 1.61 1.15E-01 9.37E-01 cation homeostasis (GO:0055080) 572 91 56.55 + 1.61 4.02E-05 2.46E-03 lamellipodium organization (GO:0097581) 44 7 4.35 + 1.61 2.20E-01 1.00E00 osteoclast differentiation (GO:0030316) 44 7 4.35 + 1.61 2.20E-01 1.00E00 regulation of cytokine-mediated signaling pathway (GO:0001959) 107 17 10.58 + 1.61 8.05E-02 8.05E-01 regulation of receptor signaling pathway via STAT (GO:1904892) 63 10 6.23 + 1.61 1.52E-01 1.00E00 coronary vasculature development (GO:0060976) 63 10 6.23 + 1.61 1.52E-01 1.00E00 negative regulation of neuron apoptotic process (GO:0043524) 145 23 14.34 + 1.60 4.09E-02 5.45E-01 positive regulation of cytosolic calcium ion concentration (GO:0007204) 227 36 22.44 + 1.60 1.19E-02 2.44E-01 regulation of cell motility (GO:2000145) 845 134 83.55 + 1.60 6.30E-07 6.69E-05 regulation of biomineralization (GO:0110149) 82 13 8.11 + 1.60 1.07E-01 8.99E-01 memory (GO:0007613) 120 19 11.86 + 1.60 7.15E-02 7.37E-01 cellular response to oxygen-containing compound (GO:1901701) 734 116 72.57 + 1.60 4.63E-06 3.88E-04 toll-like receptor 4 signaling pathway (GO:0034142) 19 3 1.88 + 1.60 4.43E-01 1.00E00 negative regulation of T-helper cell differentiation (GO:0045623) 19 3 1.88 + 1.60 4.43E-01 1.00E00 cardiac epithelial to mesenchymal transition (GO:0060317) 19 3 1.88 + 1.60 4.43E-01 1.00E00 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157) 38 6 3.76 + 1.60 2.85E-01 1.00E00 zinc ion transmembrane transport (GO:0071577) 19 3 1.88 + 1.60 4.43E-01 1.00E00 negative regulation of ATPase activity (GO:0032780) 19 3 1.88 + 1.60 4.43E-01 1.00E00 cellular response to pH (GO:0071467) 19 3 1.88 + 1.60 4.43E-01 1.00E00 regulation of interleukin-13 production (GO:0032656) 19 3 1.88 + 1.60 4.43E-01 1.00E00 regulation of AMPA receptor activity (GO:2000311) 19 3 1.88 + 1.60 4.43E-01 1.00E00 export across plasma membrane (GO:0140115) 38 6 3.76 + 1.60 2.85E-01 1.00E00 regulation of cell proliferation involved in heart morphogenesis (GO:2000136) 19 3 1.88 + 1.60 4.43E-01 1.00E00 positive regulation of neurotransmitter transport (GO:0051590) 19 3 1.88 + 1.60 4.43E-01 1.00E00 positive regulation of oligodendrocyte differentiation (GO:0048714) 19 3 1.88 + 1.60 4.43E-01 1.00E00 gluconeogenesis (GO:0006094) 19 3 1.88 + 1.60 4.43E-01 1.00E00 spleen development (GO:0048536) 38 6 3.76 + 1.60 2.85E-01 1.00E00 presynapse organization (GO:0099172) 19 3 1.88 + 1.60 4.43E-01 1.00E00 regulation of ARF protein signal transduction (GO:0032012) 19 3 1.88 + 1.60 4.43E-01 1.00E00 platelet morphogenesis (GO:0036344) 19 3 1.88 + 1.60 4.43E-01 1.00E00 protein kinase B signaling (GO:0043491) 38 6 3.76 + 1.60 2.85E-01 1.00E00 epithelial cell differentiation involved in kidney development (GO:0035850) 19 3 1.88 + 1.60 4.43E-01 1.00E00 protein autoprocessing (GO:0016540) 19 3 1.88 + 1.60 4.43E-01 1.00E00 phospholipid catabolic process (GO:0009395) 38 6 3.76 + 1.60 2.85E-01 1.00E00 monoamine transport (GO:0015844) 19 3 1.88 + 1.60 4.43E-01 1.00E00 hippo signaling (GO:0035329) 19 3 1.88 + 1.60 4.43E-01 1.00E00 exocrine system development (GO:0035272) 38 6 3.76 + 1.60 2.85E-01 1.00E00 positive regulation of fibroblast migration (GO:0010763) 19 3 1.88 + 1.60 4.43E-01 1.00E00 negative regulation of insulin receptor signaling pathway (GO:0046627) 38 6 3.76 + 1.60 2.85E-01 1.00E00 regulation of catecholamine metabolic process (GO:0042069) 19 3 1.88 + 1.60 4.43E-01 1.00E00 protein-containing complex remodeling (GO:0034367) 19 3 1.88 + 1.60 4.43E-01 1.00E00 positive regulation of lymphocyte mediated immunity (GO:0002708) 114 18 11.27 + 1.60 6.66E-02 7.38E-01 cellular divalent inorganic cation homeostasis (GO:0072503) 375 59 37.08 + 1.59 1.55E-03 5.13E-02 regulation of phosphatidylinositol 3-kinase signaling (GO:0014066) 89 14 8.80 + 1.59 1.17E-01 9.50E-01 regulation of NIK/NF-kappaB signaling (GO:1901222) 89 14 8.80 + 1.59 1.17E-01 9.49E-01 regulation of body fluid levels (GO:0050878) 248 39 24.52 + 1.59 8.97E-03 1.99E-01 regulation of locomotion (GO:0040012) 884 139 87.40 + 1.59 5.93E-07 6.38E-05 sterol homeostasis (GO:0055092) 70 11 6.92 + 1.59 1.68E-01 1.00E00 regulation of protein tyrosine kinase activity (GO:0061097) 70 11 6.92 + 1.59 1.68E-01 1.00E00 cellular chemical homeostasis (GO:0055082) 592 93 58.53 + 1.59 5.25E-05 3.09E-03 regulation of secretion (GO:0051046) 561 88 55.47 + 1.59 8.36E-05 4.48E-03 negative regulation of peptidyl-tyrosine phosphorylation (GO:0050732) 51 8 5.04 + 1.59 2.48E-01 1.00E00 chaperone-mediated protein folding (GO:0061077) 51 8 5.04 + 1.59 2.48E-01 1.00E00 regulation of vesicle-mediated transport (GO:0060627) 517 81 51.12 + 1.58 1.89E-04 9.03E-03 regulation of blood vessel endothelial cell migration (GO:0043535) 83 13 8.21 + 1.58 1.48E-01 1.00E00 cell-cell adhesion (GO:0098609) 313 49 30.95 + 1.58 3.81E-03 1.02E-01 regulation of secretion by cell (GO:1903530) 518 81 51.22 + 1.58 1.93E-04 9.15E-03 amino acid transport (GO:0006865) 96 15 9.49 + 1.58 9.65E-02 8.53E-01 regulation of fatty acid transport (GO:2000191) 32 5 3.16 + 1.58 3.78E-01 1.00E00 response to carbohydrate (GO:0009743) 96 15 9.49 + 1.58 9.65E-02 8.52E-01 regulation of myotube differentiation (GO:0010830) 32 5 3.16 + 1.58 3.78E-01 1.00E00 regulation of calcium ion transport (GO:0051924) 224 35 22.15 + 1.58 1.54E-02 2.87E-01 regulation of nervous system process (GO:0031644) 141 22 13.94 + 1.58 5.28E-02 6.30E-01 regulation of cellular component movement (GO:0051270) 911 142 90.07 + 1.58 6.40E-07 6.74E-05 regulation of response to biotic stimulus (GO:0002831) 276 43 27.29 + 1.58 7.33E-03 1.70E-01 positive regulation of wound healing (GO:0090303) 45 7 4.45 + 1.57 2.29E-01 1.00E00 positive regulation of protein binding (GO:0032092) 90 14 8.90 + 1.57 1.20E-01 9.68E-01 sterol transport (GO:0015918) 45 7 4.45 + 1.57 2.29E-01 1.00E00 striated muscle cell development (GO:0055002) 45 7 4.45 + 1.57 2.29E-01 1.00E00 cholesterol transport (GO:0030301) 45 7 4.45 + 1.57 2.29E-01 1.00E00 myofibril assembly (GO:0030239) 45 7 4.45 + 1.57 2.29E-01 1.00E00 platelet activation (GO:0030168) 45 7 4.45 + 1.57 2.29E-01 1.00E00 negative regulation of proteolysis (GO:0045861) 238 37 23.53 + 1.57 1.39E-02 2.67E-01 regulation of DNA-binding transcription factor activity (GO:0051090) 367 57 36.29 + 1.57 2.47E-03 7.42E-02 positive regulation of gene expression (GO:0010628) 992 154 98.08 + 1.57 2.44E-07 2.94E-05 glutathione metabolic process (GO:0006749) 58 9 5.73 + 1.57 1.98E-01 1.00E00 regulation of receptor signaling pathway via JAK-STAT (GO:0046425) 58 9 5.73 + 1.57 1.98E-01 1.00E00 cellular calcium ion homeostasis (GO:0006874) 355 55 35.10 + 1.57 2.81E-03 8.09E-02 mesenchymal cell development (GO:0014031) 71 11 7.02 + 1.57 1.72E-01 9.67E-01 regulation of potassium ion transport (GO:0043266) 84 13 8.31 + 1.57 1.50E-01 1.00E00 positive regulation of lipid biosynthetic process (GO:0046889) 84 13 8.31 + 1.57 1.50E-01 1.00E00 negative regulation of angiogenesis (GO:0016525) 97 15 9.59 + 1.56 1.32E-01 9.85E-01 fat cell differentiation (GO:0045444) 110 17 10.88 + 1.56 8.66E-02 8.22E-01 positive regulation of stress-activated MAPK cascade (GO:0032874) 110 17 10.88 + 1.56 8.66E-02 8.21E-01 divalent inorganic cation homeostasis (GO:0072507) 395 61 39.05 + 1.56 1.56E-03 5.14E-02 cellular ion homeostasis (GO:0006873) 525 81 51.91 + 1.56 2.81E-04 1.27E-02 regulation of MAPK cascade (GO:0043408) 590 91 58.33 + 1.56 1.19E-04 6.01E-03 regulation of carbohydrate metabolic process (GO:0006109) 169 26 16.71 + 1.56 4.27E-02 5.59E-01 negative regulation of bone resorption (GO:0045779) 13 2 1.29 + 1.56 6.39E-01 1.00E00 heart process (GO:0003015) 78 12 7.71 + 1.56 1.41E-01 1.00E00 arachidonic acid metabolic process (GO:0019369) 26 4 2.57 + 1.56 3.41E-01 1.00E00 regulation of interferon-gamma-mediated signaling pathway (GO:0060334) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of response to interferon-gamma (GO:0060330) 13 2 1.29 + 1.56 6.39E-01 1.00E00 adrenergic receptor signaling pathway (GO:0071875) 13 2 1.29 + 1.56 6.39E-01 1.00E00 positive regulation of podosome assembly (GO:0071803) 13 2 1.29 + 1.56 6.39E-01 1.00E00 spinal cord patterning (GO:0021511) 13 2 1.29 + 1.56 6.39E-01 1.00E00 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) 13 2 1.29 + 1.56 6.39E-01 1.00E00 response to tumor cell (GO:0002347) 13 2 1.29 + 1.56 6.39E-01 1.00E00 endothelial cell morphogenesis (GO:0001886) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of growth hormone secretion (GO:0060123) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of integrin-mediated signaling pathway (GO:2001044) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of exit from mitosis (GO:0007096) 13 2 1.29 + 1.56 6.39E-01 1.00E00 cell-substrate junction assembly (GO:0007044) 39 6 3.86 + 1.56 2.93E-01 1.00E00 regulation of polysaccharide metabolic process (GO:0032881) 39 6 3.86 + 1.56 2.93E-01 1.00E00 radial glial cell differentiation (GO:0060019) 13 2 1.29 + 1.56 6.39E-01 1.00E00 negative regulation of telomerase activity (GO:0051974) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235) 26 4 2.57 + 1.56 3.41E-01 1.00E00 osteoblast development (GO:0002076) 13 2 1.29 + 1.56 6.39E-01 1.00E00 protein neddylation (GO:0045116) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:1902165) 13 2 1.29 + 1.56 6.39E-01 1.00E00 negative thymic T cell selection (GO:0045060) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of axon extension involved in axon guidance (GO:0048841) 26 4 2.57 + 1.56 3.41E-01 1.00E00 regulation of oligodendrocyte differentiation (GO:0048713) 39 6 3.86 + 1.56 2.93E-01 1.00E00 positive regulation of non-canonical Wnt signaling pathway (GO:2000052) 13 2 1.29 + 1.56 6.39E-01 1.00E00 dendritic transport (GO:0098935) 13 2 1.29 + 1.56 6.39E-01 1.00E00 neuron fate specification (GO:0048665) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway (GO:0106070) 13 2 1.29 + 1.56 6.39E-01 1.00E00 sensory perception of taste (GO:0050909) 26 4 2.57 + 1.56 3.41E-01 1.00E00 regulation of pigmentation (GO:0120305) 13 2 1.29 + 1.56 6.39E-01 1.00E00 neuromuscular process controlling posture (GO:0050884) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of pinocytosis (GO:0048548) 13 2 1.29 + 1.56 6.39E-01 1.00E00 lens fiber cell development (GO:0070307) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of modification of postsynaptic structure (GO:0099159) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of autophagosome maturation (GO:1901096) 13 2 1.29 + 1.56 6.39E-01 1.00E00 postsynapse assembly (GO:0099068) 13 2 1.29 + 1.56 6.39E-01 1.00E00 cytoplasmic sequestering of transcription factor (GO:0042994) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of amyloid precursor protein biosynthetic process (GO:0042984) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of excitatory synapse assembly (GO:1904889) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of developmental pigmentation (GO:0048070) 13 2 1.29 + 1.56 6.39E-01 1.00E00 eating behavior (GO:0042755) 26 4 2.57 + 1.56 3.41E-01 1.00E00 reticulophagy (GO:0061709) 13 2 1.29 + 1.56 6.39E-01 1.00E00 vitamin transmembrane transport (GO:0035461) 13 2 1.29 + 1.56 6.39E-01 1.00E00 peptide transport (GO:0015833) 65 10 6.43 + 1.56 2.19E-01 1.00E00 nucleoside catabolic process (GO:0009164) 13 2 1.29 + 1.56 6.39E-01 1.00E00 nucleoside diphosphate catabolic process (GO:0009134) 13 2 1.29 + 1.56 6.39E-01 1.00E00 response to caffeine (GO:0031000) 13 2 1.29 + 1.56 6.39E-01 1.00E00 magnesium ion homeostasis (GO:0010960) 13 2 1.29 + 1.56 6.39E-01 1.00E00 positive regulation of hormone biosynthetic process (GO:0046886) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of lipid storage (GO:0010883) 39 6 3.86 + 1.56 2.93E-01 1.00E00 regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) 13 2 1.29 + 1.56 6.39E-01 1.00E00 positive regulation of phospholipase C activity (GO:0010863) 26 4 2.57 + 1.56 3.41E-01 1.00E00 negative regulation of cell morphogenesis involved in differentiation (GO:0010771) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of transcription from RNA polymerase II promoter in response to hypoxia (GO:0061418) 13 2 1.29 + 1.56 6.39E-01 1.00E00 embryonic hemopoiesis (GO:0035162) 26 4 2.57 + 1.56 3.41E-01 1.00E00 regulation of plasma membrane organization (GO:1903729) 13 2 1.29 + 1.56 6.39E-01 1.00E00 positive regulation of phospholipid metabolic process (GO:1903727) 13 2 1.29 + 1.56 6.39E-01 1.00E00 lipid storage (GO:0019915) 39 6 3.86 + 1.56 2.93E-01 1.00E00 negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of glycoprotein biosynthetic process (GO:0010559) 39 6 3.86 + 1.56 2.93E-01 1.00E00 protein localization to phagophore assembly site (GO:0034497) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of morphogenesis of a branching structure (GO:0060688) 52 8 5.14 + 1.56 2.53E-01 1.00E00 mammary gland epithelial cell differentiation (GO:0060644) 13 2 1.29 + 1.56 6.39E-01 1.00E00 craniofacial suture morphogenesis (GO:0097094) 13 2 1.29 + 1.56 6.39E-01 1.00E00 regulation of glial cell apoptotic process (GO:0034350) 13 2 1.29 + 1.56 6.39E-01 1.00E00 pyramidal neuron differentiation (GO:0021859) 13 2 1.29 + 1.56 6.39E-01 1.00E00 positive regulation of dendritic spine morphogenesis (GO:0061003) 26 4 2.57 + 1.56 3.41E-01 1.00E00 cell migration (GO:0016477) 730 112 72.18 + 1.55 2.38E-05 1.53E-03 regulation of endothelial cell migration (GO:0010594) 144 22 14.24 + 1.55 7.42E-02 7.52E-01 cell maturation (GO:0048469) 131 20 12.95 + 1.54 8.41E-02 8.33E-01 response to mechanical stimulus (GO:0009612) 118 18 11.67 + 1.54 9.57E-02 8.47E-01 positive regulation of hormone secretion (GO:0046887) 118 18 11.67 + 1.54 9.57E-02 8.46E-01 ADP metabolic process (GO:0046031) 46 7 4.55 + 1.54 3.29E-01 1.00E00 regulation of endothelial cell apoptotic process (GO:2000351) 46 7 4.55 + 1.54 3.29E-01 1.00E00 regulation of lipid catabolic process (GO:0050994) 46 7 4.55 + 1.54 3.29E-01 1.00E00 actin filament-based process (GO:0030029) 506 77 50.03 + 1.54 6.56E-04 2.60E-02 ion homeostasis (GO:0050801) 618 94 61.10 + 1.54 1.64E-04 7.91E-03 positive regulation of stress-activated protein kinase signaling cascade (GO:0070304) 112 17 11.07 + 1.54 1.19E-01 9.65E-01 semaphorin-plexin signaling pathway (GO:0071526) 33 5 3.26 + 1.53 3.86E-01 1.00E00 negative regulation of blood vessel morphogenesis (GO:2000181) 99 15 9.79 + 1.53 1.36E-01 1.00E00 glycosaminoglycan biosynthetic process (GO:0006024) 33 5 3.26 + 1.53 3.86E-01 1.00E00 negative regulation of protein localization to membrane (GO:1905476) 33 5 3.26 + 1.53 3.86E-01 1.00E00 viral entry into host cell (GO:0046718) 33 5 3.26 + 1.53 3.86E-01 1.00E00 regulation of alpha-beta T cell activation (GO:0046634) 99 15 9.79 + 1.53 1.36E-01 1.00E00 positive regulation of muscle cell apoptotic process (GO:0010661) 33 5 3.26 + 1.53 3.86E-01 1.00E00 response to stress (GO:0006950) 2559 387 253.01 + 1.53 1.06E-16 5.17E-14 negative regulation of lipid metabolic process (GO:0045833) 86 13 8.50 + 1.53 1.56E-01 1.00E00 regulation of cellular carbohydrate metabolic process (GO:0010675) 139 21 13.74 + 1.53 7.10E-02 7.33E-01 negative regulation of cytokine-mediated signaling pathway (GO:0001960) 53 8 5.24 + 1.53 2.59E-01 1.00E00 lipid homeostasis (GO:0055088) 126 19 12.46 + 1.53 1.06E-01 8.96E-01 negative regulation of myeloid cell differentiation (GO:0045638) 73 11 7.22 + 1.52 1.81E-01 1.00E00 regulation of T cell differentiation (GO:0045580) 146 22 14.44 + 1.52 7.61E-02 7.71E-01 positive regulation of lipid transport (GO:0032370) 73 11 7.22 + 1.52 1.81E-01 1.00E00 fatty acid biosynthetic process (GO:0006633) 93 14 9.20 + 1.52 1.71E-01 1.00E00 regulation of epithelial cell migration (GO:0010632) 206 31 20.37 + 1.52 3.84E-02 5.32E-01 cellular cation homeostasis (GO:0030003) 512 77 50.62 + 1.52 9.13E-04 3.35E-02 calcium ion homeostasis (GO:0055074) 366 55 36.19 + 1.52 5.52E-03 1.36E-01 negative regulation of peptidyl-lysine acetylation (GO:2000757) 20 3 1.98 + 1.52 4.57E-01 1.00E00 cholesterol efflux (GO:0033344) 20 3 1.98 + 1.52 4.57E-01 1.00E00 cellular modified amino acid metabolic process (GO:0006575) 140 21 13.84 + 1.52 9.44E-02 8.71E-01 negative regulation of axon extension involved in axon guidance (GO:0048843) 20 3 1.98 + 1.52 4.57E-01 1.00E00 positive regulation of multi-organism process (GO:0043902) 20 3 1.98 + 1.52 4.57E-01 1.00E00 regulation of vascular endothelial growth factor signaling pathway (GO:1900746) 20 3 1.98 + 1.52 4.57E-01 1.00E00 peptidyl-threonine dephosphorylation (GO:0035970) 20 3 1.98 + 1.52 4.57E-01 1.00E00 positive regulation of potassium ion transmembrane transporter activity (GO:1901018) 20 3 1.98 + 1.52 4.57E-01 1.00E00 mitochondrion distribution (GO:0048311) 20 3 1.98 + 1.52 4.57E-01 1.00E00 regulation of urine volume (GO:0035809) 20 3 1.98 + 1.52 4.57E-01 1.00E00 regulation of catecholamine secretion (GO:0050433) 40 6 3.95 + 1.52 3.02E-01 1.00E00 negative regulation of vascular associated smooth muscle cell proliferation (GO:1904706) 20 3 1.98 + 1.52 4.57E-01 1.00E00 regulation of synaptic vesicle endocytosis (GO:1900242) 20 3 1.98 + 1.52 4.57E-01 1.00E00 ventricular cardiac muscle tissue morphogenesis (GO:0055010) 40 6 3.95 + 1.52 3.02E-01 1.00E00 cell-substrate junction organization (GO:0150115) 40 6 3.95 + 1.52 3.02E-01 1.00E00 dopamine metabolic process (GO:0042417) 20 3 1.98 + 1.52 4.57E-01 1.00E00 regulation of triglyceride biosynthetic process (GO:0010866) 20 3 1.98 + 1.52 4.57E-01 1.00E00 negative regulation of cellular protein localization (GO:1903828) 120 18 11.86 + 1.52 9.97E-02 8.67E-01 positive regulation of sprouting angiogenesis (GO:1903672) 20 3 1.98 + 1.52 4.57E-01 1.00E00 outflow tract morphogenesis (GO:0003151) 60 9 5.93 + 1.52 2.86E-01 1.00E00 negative regulation of vasculature development (GO:1901343) 100 15 9.89 + 1.52 1.39E-01 1.00E00 negative regulation of multicellular organismal process (GO:0051241) 880 132 87.01 + 1.52 1.15E-05 8.41E-04 response to oxygen-containing compound (GO:1901700) 1044 156 103.22 + 1.51 1.68E-06 1.57E-04 actin cytoskeleton organization (GO:0030036) 462 69 45.68 + 1.51 1.95E-03 6.08E-02 hormone transport (GO:0009914) 67 10 6.62 + 1.51 2.27E-01 1.00E00 regulation of lipid metabolic process (GO:0019216) 295 44 29.17 + 1.51 1.25E-02 2.54E-01 regulation of cell morphogenesis (GO:0022604) 295 44 29.17 + 1.51 1.25E-02 2.53E-01 endothelial cell development (GO:0001885) 47 7 4.65 + 1.51 3.34E-01 1.00E00 negative regulation of reactive oxygen species metabolic process (GO:2000378) 47 7 4.65 + 1.51 3.34E-01 1.00E00 ventricular cardiac muscle tissue development (GO:0003229) 47 7 4.65 + 1.51 3.34E-01 1.00E00 regulation of exocytosis (GO:0017157) 195 29 19.28 + 1.50 4.48E-02 5.60E-01 regulation of biological process involved in symbiotic interaction (GO:0043903) 74 11 7.32 + 1.50 1.86E-01 1.00E00 negative regulation of protein-containing complex disassembly (GO:0043242) 74 11 7.32 + 1.50 1.86E-01 1.00E00 negative regulation of apoptotic signaling pathway (GO:2001234) 209 31 20.66 + 1.50 4.00E-02 5.40E-01 leukocyte apoptotic process (GO:0071887) 27 4 2.67 + 1.50 3.57E-01 1.00E00 regulation of protein processing (GO:0070613) 54 8 5.34 + 1.50 2.65E-01 1.00E00 positive regulation of macrophage migration (GO:1905523) 27 4 2.67 + 1.50 3.57E-01 1.00E00 ERK1 and ERK2 cascade (GO:0070371) 27 4 2.67 + 1.50 3.57E-01 1.00E00 regulation of presynapse organization (GO:0099174) 27 4 2.67 + 1.50 3.57E-01 1.00E00 regulation of endocrine process (GO:0044060) 27 4 2.67 + 1.50 3.57E-01 1.00E00 photoperiodism (GO:0009648) 27 4 2.67 + 1.50 3.57E-01 1.00E00 entrainment of circadian clock by photoperiod (GO:0043153) 27 4 2.67 + 1.50 3.57E-01 1.00E00 regulation of ossification (GO:0030278) 108 16 10.68 + 1.50 1.53E-01 1.00E00 monosaccharide biosynthetic process (GO:0046364) 27 4 2.67 + 1.50 3.57E-01 1.00E00 regulation of cellular response to oxidative stress (GO:1900407) 81 12 8.01 + 1.50 2.00E-01 1.00E00 cellular response to peptide (GO:1901653) 203 30 20.07 + 1.49 4.87E-02 5.98E-01 response to purine-containing compound (GO:0014074) 88 13 8.70 + 1.49 1.64E-01 1.00E00 regulation of response to oxidative stress (GO:1902882) 88 13 8.70 + 1.49 1.64E-01 1.00E00 negative regulation of supramolecular fiber organization (GO:1902904) 149 22 14.73 + 1.49 8.03E-02 8.04E-01 developmental maturation (GO:0021700) 210 31 20.76 + 1.49 4.07E-02 5.42E-01 multicellular organismal response to stress (GO:0033555) 61 9 6.03 + 1.49 2.90E-01 1.00E00 regulation of peptidase activity (GO:0052547) 305 45 30.16 + 1.49 1.39E-02 2.69E-01 regulation of antigen receptor-mediated signaling pathway (GO:0050854) 61 9 6.03 + 1.49 2.90E-01 1.00E00 regulation of fat cell differentiation (GO:0045598) 129 19 12.75 + 1.49 1.11E-01 9.17E-01 positive regulation of protein secretion (GO:0050714) 129 19 12.75 + 1.49 1.11E-01 9.17E-01 chemical homeostasis (GO:0048878) 897 132 88.69 + 1.49 2.29E-05 1.48E-03 B cell homeostasis (GO:0001782) 34 5 3.36 + 1.49 3.94E-01 1.00E00 regulation of intrinsic apoptotic signaling pathway in response to DNA damage (GO:1902229) 34 5 3.36 + 1.49 3.94E-01 1.00E00 regulation of amyloid-beta formation (GO:1902003) 34 5 3.36 + 1.49 3.94E-01 1.00E00 entry into host (GO:0044409) 34 5 3.36 + 1.49 3.94E-01 1.00E00 zymogen activation (GO:0031638) 34 5 3.36 + 1.49 3.94E-01 1.00E00 autonomic nervous system development (GO:0048483) 34 5 3.36 + 1.49 3.94E-01 1.00E00 prostate gland development (GO:0030850) 34 5 3.36 + 1.49 3.94E-01 1.00E00 developmental pigmentation (GO:0048066) 34 5 3.36 + 1.49 3.94E-01 1.00E00 regulation of cytosolic calcium ion concentration (GO:0051480) 259 38 25.61 + 1.48 2.44E-02 3.90E-01 detection of stimulus involved in sensory perception (GO:0050906) 75 11 7.42 + 1.48 2.52E-01 1.00E00 ventricular septum morphogenesis (GO:0060412) 41 6 4.05 + 1.48 3.12E-01 1.00E00 negative regulation of alpha-beta T cell activation (GO:0046636) 41 6 4.05 + 1.48 3.12E-01 1.00E00 bone mineralization (GO:0030282) 41 6 4.05 + 1.48 3.12E-01 1.00E00 positive regulation of pri-miRNA transcription by RNA polymerase II (GO:1902895) 41 6 4.05 + 1.48 3.12E-01 1.00E00 cellular response to organic substance (GO:0071310) 1497 219 148.01 + 1.48 3.68E-08 5.12E-06 regulation of lipid localization (GO:1905952) 137 20 13.55 + 1.48 1.21E-01 9.70E-01 positive regulation of peptide secretion (GO:0002793) 96 14 9.49 + 1.47 1.79E-01 9.96E-01 organic anion transport (GO:0015711) 206 30 20.37 + 1.47 5.08E-02 6.10E-01 negative regulation of adaptive immune response (GO:0002820) 55 8 5.44 + 1.47 2.72E-01 1.00E00 monocarboxylic acid biosynthetic process (GO:0072330) 124 18 12.26 + 1.47 1.38E-01 1.00E00 locomotion (GO:0040011) 972 141 96.10 + 1.47 2.19E-05 1.43E-03 phospholipid transport (GO:0015914) 69 10 6.82 + 1.47 2.37E-01 1.00E00 regulation of small molecule metabolic process (GO:0062012) 297 43 29.36 + 1.46 2.13E-02 3.59E-01 biological process involved in interaction with host (GO:0051701) 76 11 7.51 + 1.46 2.55E-01 1.00E00 regulation of smooth muscle cell migration (GO:0014910) 83 12 8.21 + 1.46 2.07E-01 1.00E00 response to toxic substance (GO:0009636) 97 14 9.59 + 1.46 1.82E-01 1.00E00 negative regulation of catalytic activity (GO:0043086) 520 75 51.41 + 1.46 2.69E-03 7.84E-02 regulation of multicellular organismal process (GO:0051239) 2262 326 223.65 + 1.46 2.18E-11 4.46E-09 vesicle-mediated transport (GO:0016192) 1062 153 105.00 + 1.46 1.42E-05 1.00E-03 cellular response to chemical stimulus (GO:0070887) 1939 279 191.71 + 1.46 1.14E-09 2.06E-07 positive regulation of kinase activity (GO:0033674) 431 62 42.61 + 1.45 6.49E-03 1.55E-01 regulation of lipid biosynthetic process (GO:0046890) 160 23 15.82 + 1.45 9.14E-02 8.51E-01 circulatory system process (GO:0003013) 334 48 33.02 + 1.45 1.82E-02 3.25E-01 regulation of multicellular organismal development (GO:2000026) 1176 169 116.27 + 1.45 5.54E-06 4.56E-04 positive regulation of intracellular signal transduction (GO:1902533) 823 118 81.37 + 1.45 2.07E-04 9.75E-03 regulation of oxidative stress-induced cell death (GO:1903201) 70 10 6.92 + 1.44 2.43E-01 1.00E00 vascular process in circulatory system (GO:0003018) 175 25 17.30 + 1.44 8.23E-02 8.17E-01 ether metabolic process (GO:0018904) 21 3 2.08 + 1.44 4.72E-01 1.00E00 negative regulation of toll-like receptor signaling pathway (GO:0034122) 35 5 3.46 + 1.44 4.03E-01 1.00E00 negative regulation of tissue remodeling (GO:0034104) 21 3 2.08 + 1.44 4.72E-01 1.00E00 regulation of osteoclast differentiation (GO:0045670) 63 9 6.23 + 1.44 2.98E-01 1.00E00 regulation of activated T cell proliferation (GO:0046006) 35 5 3.46 + 1.44 4.03E-01 1.00E00 regulation of neuron migration (GO:2001222) 42 6 4.15 + 1.44 4.42E-01 1.00E00 negative regulation of endothelial cell proliferation (GO:0001937) 35 5 3.46 + 1.44 4.03E-01 1.00E00 positive regulation of glial cell proliferation (GO:0060252) 21 3 2.08 + 1.44 4.72E-01 1.00E00 protein-lipid complex assembly (GO:0065005) 21 3 2.08 + 1.44 4.72E-01 1.00E00 positive regulation of transcription regulatory region DNA binding (GO:2000679) 21 3 2.08 + 1.44 4.72E-01 1.00E00 regulation of collagen biosynthetic process (GO:0032965) 42 6 4.15 + 1.44 4.42E-01 1.00E00 neural crest cell migration (GO:0001755) 42 6 4.15 + 1.44 4.42E-01 1.00E00 positive regulation of cardiac muscle cell proliferation (GO:0060045) 21 3 2.08 + 1.44 4.72E-01 1.00E00 positive regulation of sodium ion transmembrane transport (GO:1902307) 21 3 2.08 + 1.44 4.72E-01 1.00E00 response to dexamethasone (GO:0071548) 21 3 2.08 + 1.44 4.72E-01 1.00E00 positive regulation of peptidyl-serine phosphorylation (GO:0033138) 91 13 9.00 + 1.44 2.25E-01 1.00E00 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus (GO:1901522) 21 3 2.08 + 1.44 4.72E-01 1.00E00 positive regulation of fatty acid transport (GO:2000193) 21 3 2.08 + 1.44 4.72E-01 1.00E00 mesenchymal cell differentiation (GO:0048762) 126 18 12.46 + 1.44 1.43E-01 1.00E00 transepithelial transport (GO:0070633) 21 3 2.08 + 1.44 4.72E-01 1.00E00 regulation of icosanoid secretion (GO:0032303) 21 3 2.08 + 1.44 4.72E-01 1.00E00 negative regulation of lipid catabolic process (GO:0050995) 21 3 2.08 + 1.44 4.72E-01 1.00E00 calcium ion import (GO:0070509) 42 6 4.15 + 1.44 4.42E-01 1.00E00 negative regulation of T cell receptor signaling pathway (GO:0050860) 21 3 2.08 + 1.44 4.72E-01 1.00E00 response to sterol (GO:0036314) 21 3 2.08 + 1.44 4.72E-01 1.00E00 detection of abiotic stimulus (GO:0009582) 91 13 9.00 + 1.44 2.25E-01 1.00E00 amyloid precursor protein metabolic process (GO:0042982) 21 3 2.08 + 1.44 4.72E-01 1.00E00 cellular response to decreased oxygen levels (GO:0036294) 84 12 8.31 + 1.44 2.12E-01 1.00E00 positive regulation of histone deacetylation (GO:0031065) 21 3 2.08 + 1.44 4.72E-01 1.00E00 homeostatic process (GO:0042592) 1372 196 135.65 + 1.44 1.02E-06 1.01E-04 positive regulation of macrophage chemotaxis (GO:0010759) 21 3 2.08 + 1.44 4.72E-01 1.00E00 left/right pattern formation (GO:0060972) 21 3 2.08 + 1.44 4.72E-01 1.00E00 regulation of alpha-beta T cell differentiation (GO:0046637) 63 9 6.23 + 1.44 2.98E-01 1.00E00 positive regulation of insulin receptor signaling pathway (GO:0046628) 21 3 2.08 + 1.44 4.72E-01 1.00E00 positive regulation of glycoprotein biosynthetic process (GO:0010560) 21 3 2.08 + 1.44 4.72E-01 1.00E00 negative regulation of natural killer cell mediated immunity (GO:0002716) 21 3 2.08 + 1.44 4.72E-01 1.00E00 regulation of natural killer cell mediated immunity (GO:0002715) 42 6 4.15 + 1.44 4.42E-01 1.00E00 positive regulation of fibroblast growth factor receptor signaling pathway (GO:0045743) 7 1 .69 + 1.44 5.30E-01 1.00E00 renal water homeostasis (GO:0003091) 7 1 .69 + 1.44 5.30E-01 1.00E00 salivary gland development (GO:0007431) 28 4 2.77 + 1.44 5.28E-01 1.00E00 lung-associated mesenchyme development (GO:0060484) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of neuroblast proliferation (GO:0007406) 7 1 .69 + 1.44 5.30E-01 1.00E00 tetrahydrobiopterin metabolic process (GO:0046146) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of toll-like receptor 2 signaling pathway (GO:0034137) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of antigen processing and presentation of peptide antigen (GO:0002583) 7 1 .69 + 1.44 5.30E-01 1.00E00 activation-induced cell death of T cells (GO:0006924) 7 1 .69 + 1.44 5.30E-01 1.00E00 pyridine nucleotide catabolic process (GO:0019364) 7 1 .69 + 1.44 5.30E-01 1.00E00 cardiac muscle cell myoblast differentiation (GO:0060379) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of Fc receptor mediated stimulatory signaling pathway (GO:0060369) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of neuroblast proliferation (GO:1902692) 28 4 2.77 + 1.44 5.28E-01 1.00E00 regulation of behavioral fear response (GO:2000822) 7 1 .69 + 1.44 5.30E-01 1.00E00 corpus callosum morphogenesis (GO:0021540) 7 1 .69 + 1.44 5.30E-01 1.00E00 cell proliferation in hindbrain (GO:0021534) 7 1 .69 + 1.44 5.30E-01 1.00E00 activation of NF-kappaB-inducing kinase activity (GO:0007250) 14 2 1.38 + 1.44 6.50E-01 1.00E00 xenobiotic glucuronidation (GO:0052697) 7 1 .69 + 1.44 5.30E-01 1.00E00 flavonoid glucuronidation (GO:0052696) 7 1 .69 + 1.44 5.30E-01 1.00E00 cellular glucuronidation (GO:0052695) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of mesenchymal stem cell differentiation (GO:2000739) 7 1 .69 + 1.44 5.30E-01 1.00E00 detection of cell density (GO:0060245) 7 1 .69 + 1.44 5.30E-01 1.00E00 contact inhibition (GO:0060242) 7 1 .69 + 1.44 5.30E-01 1.00E00 hematopoietic stem cell differentiation (GO:0060218) 14 2 1.38 + 1.44 6.50E-01 1.00E00 primitive hemopoiesis (GO:0060215) 7 1 .69 + 1.44 5.30E-01 1.00E00 tetrahydrobiopterin biosynthetic process (GO:0006729) 7 1 .69 + 1.44 5.30E-01 1.00E00 response to nitric oxide (GO:0071731) 14 2 1.38 + 1.44 6.50E-01 1.00E00 positive regulation of endocytic recycling (GO:2001137) 7 1 .69 + 1.44 5.30E-01 1.00E00 ureter morphogenesis (GO:0072197) 7 1 .69 + 1.44 5.30E-01 1.00E00 ureter development (GO:0072189) 14 2 1.38 + 1.44 6.50E-01 1.00E00 neural fold formation (GO:0001842) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of lipase activity (GO:0060192) 14 2 1.38 + 1.44 6.50E-01 1.00E00 ribonucleoprotein complex disassembly (GO:0032988) 7 1 .69 + 1.44 5.30E-01 1.00E00 inositol phosphate biosynthetic process (GO:0032958) 14 2 1.38 + 1.44 6.50E-01 1.00E00 ceramide metabolic process (GO:0006672) 77 11 7.61 + 1.44 2.59E-01 1.00E00 posttranslational protein targeting to endoplasmic reticulum membrane (GO:0006620) 14 2 1.38 + 1.44 6.50E-01 1.00E00 SRP-dependent cotranslational protein targeting to membrane, translocation (GO:0006616) 7 1 .69 + 1.44 5.30E-01 1.00E00 xenobiotic detoxification by transmembrane export across the plasma membrane (GO:1990961) 7 1 .69 + 1.44 5.30E-01 1.00E00 hematopoietic progenitor cell differentiation (GO:0002244) 105 15 10.38 + 1.44 1.97E-01 1.00E00 vocalization behavior (GO:0071625) 14 2 1.38 + 1.44 6.50E-01 1.00E00 positive regulation of mitotic sister chromatid separation (GO:1901970) 14 2 1.38 + 1.44 6.50E-01 1.00E00 double-strand break repair involved in meiotic recombination (GO:1990918) 7 1 .69 + 1.44 5.30E-01 1.00E00 relaxation of vascular associated smooth muscle (GO:0060087) 7 1 .69 + 1.44 5.30E-01 1.00E00 tubulin complex assembly (GO:0007021) 7 1 .69 + 1.44 5.30E-01 1.00E00 nerve growth factor signaling pathway (GO:0038180) 7 1 .69 + 1.44 5.30E-01 1.00E00 glomerular epithelium development (GO:0072010) 14 2 1.38 + 1.44 6.50E-01 1.00E00 glomerular basement membrane development (GO:0032836) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of synapse assembly (GO:0051964) 7 1 .69 + 1.44 5.30E-01 1.00E00 iron import into cell (GO:0033212) 7 1 .69 + 1.44 5.30E-01 1.00E00 adiponectin-activated signaling pathway (GO:0033211) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of CREB transcription factor activity (GO:0032793) 14 2 1.38 + 1.44 6.50E-01 1.00E00 neuron projection extension involved in neuron projection guidance (GO:1902284) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902255) 7 1 .69 + 1.44 5.30E-01 1.00E00 cellular response to UV-B (GO:0071493) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067) 14 2 1.38 + 1.44 6.50E-01 1.00E00 regulation of serotonin secretion (GO:0014062) 7 1 .69 + 1.44 5.30E-01 1.00E00 neural crest formation (GO:0014029) 7 1 .69 + 1.44 5.30E-01 1.00E00 translational termination (GO:0006415) 7 1 .69 + 1.44 5.30E-01 1.00E00 neuron death (GO:0070997) 56 8 5.54 + 1.44 3.76E-01 1.00E00 regulation of histone deacetylase activity (GO:1901725) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of glucokinase activity (GO:0033131) 7 1 .69 + 1.44 5.30E-01 1.00E00 protein localization to endoplasmic reticulum exit site (GO:0070973) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of hepatocyte proliferation (GO:2000347) 14 2 1.38 + 1.44 6.50E-01 1.00E00 regulation of interleukin-18 production (GO:0032661) 7 1 .69 + 1.44 5.30E-01 1.00E00 interleukin-4 production (GO:0032633) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) 14 2 1.38 + 1.44 6.50E-01 1.00E00 positive regulation of hair follicle development (GO:0051798) 7 1 .69 + 1.44 5.30E-01 1.00E00 skeletal muscle acetylcholine-gated channel clustering (GO:0071340) 7 1 .69 + 1.44 5.30E-01 1.00E00 cellular response to caffeine (GO:0071313) 7 1 .69 + 1.44 5.30E-01 1.00E00 nucleoside transmembrane transport (GO:1901642) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning (GO:1901621) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of bile acid biosynthetic process (GO:0070857) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of mast cell activation involved in immune response (GO:0033007) 7 1 .69 + 1.44 5.30E-01 1.00E00 inclusion body assembly (GO:0070841) 7 1 .69 + 1.44 5.30E-01 1.00E00 response to L-glutamate (GO:1902065) 7 1 .69 + 1.44 5.30E-01 1.00E00 late endosome to vacuole transport via multivesicular body sorting pathway (GO:0032511) 14 2 1.38 + 1.44 6.50E-01 1.00E00 detection of stimulus (GO:0051606) 147 21 14.53 + 1.44 1.34E-01 9.91E-01 axon extension involved in axon guidance (GO:0048846) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of lymphocyte chemotaxis (GO:0140131) 14 2 1.38 + 1.44 6.50E-01 1.00E00 melanosome transport (GO:0032402) 14 2 1.38 + 1.44 6.50E-01 1.00E00 establishment of melanosome localization (GO:0032401) 14 2 1.38 + 1.44 6.50E-01 1.00E00 2-oxoglutarate metabolic process (GO:0006103) 14 2 1.38 + 1.44 6.50E-01 1.00E00 regulation of lymphangiogenesis (GO:1901490) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090267) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of inclusion body assembly (GO:0090261) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of histone H4 acetylation (GO:0090241) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of spindle checkpoint (GO:0090232) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of cytoskeleton organization (GO:0051494) 147 21 14.53 + 1.44 1.34E-01 9.90E-01 positive regulation of store-operated calcium channel activity (GO:1901341) 7 1 .69 + 1.44 5.30E-01 1.00E00 protein kinase C signaling (GO:0070528) 14 2 1.38 + 1.44 6.50E-01 1.00E00 positive regulation of pigment cell differentiation (GO:0050942) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of skeletal muscle tissue growth (GO:0048633) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of skeletal muscle tissue growth (GO:0048631) 7 1 .69 + 1.44 5.30E-01 1.00E00 pigment cell differentiation (GO:0050931) 28 4 2.77 + 1.44 5.28E-01 1.00E00 positive regulation of neurotrophin TRK receptor signaling pathway (GO:0051388) 7 1 .69 + 1.44 5.30E-01 1.00E00 modification of postsynaptic actin cytoskeleton (GO:0098885) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of artery morphogenesis (GO:1905653) 7 1 .69 + 1.44 5.30E-01 1.00E00 neurotransmitter reuptake (GO:0098810) 14 2 1.38 + 1.44 6.50E-01 1.00E00 regulation of extracellular matrix assembly (GO:1901201) 14 2 1.38 + 1.44 6.50E-01 1.00E00 regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway (GO:0070432) 7 1 .69 + 1.44 5.30E-01 1.00E00 nucleotide-binding oligomerization domain containing 2 signaling pathway (GO:0070431) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of B cell receptor signaling pathway (GO:0050859) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) 28 4 2.77 + 1.44 5.28E-01 1.00E00 nucleotide-binding oligomerization domain containing signaling pathway (GO:0070423) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of synaptic transmission (GO:0050805) 56 8 5.54 + 1.44 3.76E-01 1.00E00 negative regulation of response to nutrient levels (GO:0032108) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of response to extracellular stimulus (GO:0032105) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of appetite (GO:0032099) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of response to food (GO:0032096) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of Fc-gamma receptor signaling pathway involved in phagocytosis (GO:1905449) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of actin nucleation (GO:0051126) 7 1 .69 + 1.44 5.30E-01 1.00E00 entrainment of circadian clock (GO:0009649) 28 4 2.77 + 1.44 5.28E-01 1.00E00 regulation of DNA binding (GO:0051101) 105 15 10.38 + 1.44 1.97E-01 1.00E00 observational learning (GO:0098597) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of isotype switching to IgA isotypes (GO:0048296) 7 1 .69 + 1.44 5.30E-01 1.00E00 activation of Janus kinase activity (GO:0042976) 7 1 .69 + 1.44 5.30E-01 1.00E00 tRNA aminoacylation for mitochondrial protein translation (GO:0070127) 7 1 .69 + 1.44 5.30E-01 1.00E00 tripeptide transport (GO:0042939) 7 1 .69 + 1.44 5.30E-01 1.00E00 COPII vesicle coating (GO:0048208) 7 1 .69 + 1.44 5.30E-01 1.00E00 vesicle targeting, rough ER to cis-Golgi (GO:0048207) 7 1 .69 + 1.44 5.30E-01 1.00E00 paranodal junction assembly (GO:0030913) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative T cell selection (GO:0043383) 14 2 1.38 + 1.44 6.50E-01 1.00E00 regulation of glucagon secretion (GO:0070092) 7 1 .69 + 1.44 5.30E-01 1.00E00 autophagic cell death (GO:0048102) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of vascular associated smooth muscle cell proliferation (GO:1904705) 56 8 5.54 + 1.44 3.76E-01 1.00E00 cleavage furrow formation (GO:0036089) 7 1 .69 + 1.44 5.30E-01 1.00E00 fibrinolysis (GO:0042730) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of cytoplasmic translational elongation (GO:1900247) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of amyloid-beta clearance (GO:1900223) 7 1 .69 + 1.44 5.30E-01 1.00E00 axon regeneration (GO:0031103) 14 2 1.38 + 1.44 6.50E-01 1.00E00 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900153) 14 2 1.38 + 1.44 6.50E-01 1.00E00 regulation of defense response to fungus (GO:1900150) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of execution phase of apoptosis (GO:1900118) 7 1 .69 + 1.44 5.30E-01 1.00E00 response to hyperoxia (GO:0055093) 7 1 .69 + 1.44 5.30E-01 1.00E00 phospholipid homeostasis (GO:0055091) 14 2 1.38 + 1.44 6.50E-01 1.00E00 heme transport (GO:0015886) 7 1 .69 + 1.44 5.30E-01 1.00E00 dopamine transport (GO:0015872) 7 1 .69 + 1.44 5.30E-01 1.00E00 nucleoside transport (GO:0015858) 7 1 .69 + 1.44 5.30E-01 1.00E00 cardiac muscle tissue morphogenesis (GO:0055008) 49 7 4.84 + 1.44 3.46E-01 1.00E00 purine ribonucleoside diphosphate metabolic process (GO:0009179) 49 7 4.84 + 1.44 3.46E-01 1.00E00 proline transport (GO:0015824) 7 1 .69 + 1.44 5.30E-01 1.00E00 Golgi to plasma membrane protein transport (GO:0043001) 28 4 2.77 + 1.44 5.28E-01 1.00E00 arginine transport (GO:0015809) 7 1 .69 + 1.44 5.30E-01 1.00E00 purine nucleoside diphosphate metabolic process (GO:0009135) 49 7 4.84 + 1.44 3.46E-01 1.00E00 PML body organization (GO:0030578) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of lipoprotein particle clearance (GO:0010985) 7 1 .69 + 1.44 5.30E-01 1.00E00 O-glycan processing (GO:0016266) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of protein K63-linked ubiquitination (GO:1900045) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of BMP signaling pathway (GO:0030513) 28 4 2.77 + 1.44 5.28E-01 1.00E00 lysosomal microautophagy (GO:0016237) 7 1 .69 + 1.44 5.30E-01 1.00E00 chaperone-mediated autophagy (GO:0061684) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of eating behavior (GO:1903998) 7 1 .69 + 1.44 5.30E-01 1.00E00 peroxisome proliferator activated receptor signaling pathway (GO:0035357) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of cardiac muscle cell contraction (GO:0086004) 28 4 2.77 + 1.44 5.28E-01 1.00E00 gamma-delta T cell differentiation (GO:0042492) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of neuromuscular junction development (GO:1904396) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of skeletal muscle acetylcholine-gated channel clustering (GO:1904393) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of protein catabolic process in the vacuole (GO:1904350) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of keratinocyte proliferation (GO:0010838) 7 1 .69 + 1.44 5.30E-01 1.00E00 amyloid-beta clearance by transcytosis (GO:0150093) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of iron ion transport (GO:0034756) 7 1 .69 + 1.44 5.30E-01 1.00E00 piecemeal microautophagy of the nucleus (GO:0034727) 7 1 .69 + 1.44 5.30E-01 1.00E00 angiogenesis involved in coronary vascular morphogenesis (GO:0060978) 7 1 .69 + 1.44 5.30E-01 1.00E00 cardiac pacemaker cell development (GO:0060926) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of alpha-beta T cell proliferation (GO:0046642) 14 2 1.38 + 1.44 6.50E-01 1.00E00 glutathione transport (GO:0034635) 7 1 .69 + 1.44 5.30E-01 1.00E00 zymogen inhibition (GO:0097341) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of microglial cell migration (GO:1904139) 7 1 .69 + 1.44 5.30E-01 1.00E00 response to laminar fluid shear stress (GO:0034616) 7 1 .69 + 1.44 5.30E-01 1.00E00 Notch signaling involved in heart development (GO:0061314) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of Rac protein signal transduction (GO:0035022) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of photoreceptor cell differentiation (GO:0046533) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of photoreceptor cell differentiation (GO:0046532) 7 1 .69 + 1.44 5.30E-01 1.00E00 regulation of gap junction assembly (GO:1903596) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of epithelial cell proliferation involved in prostate gland development (GO:0060770) 7 1 .69 + 1.44 5.30E-01 1.00E00 pericardium morphogenesis (GO:0003344) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of mast cell chemotaxis (GO:0060754) 7 1 .69 + 1.44 5.30E-01 1.00E00 muscle hypertrophy (GO:0014896) 28 4 2.77 + 1.44 5.28E-01 1.00E00 epithelial fluid transport (GO:0042045) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of striated muscle contraction (GO:0045988) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of dopamine metabolic process (GO:0045964) 7 1 .69 + 1.44 5.30E-01 1.00E00 negative regulation of complement activation, classical pathway (GO:0045959) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of catecholamine metabolic process (GO:0045915) 7 1 .69 + 1.44 5.30E-01 1.00E00 osteoclast fusion (GO:0072675) 7 1 .69 + 1.44 5.30E-01 1.00E00 mesenchymal-epithelial cell signaling (GO:0060638) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process (GO:1902961) 7 1 .69 + 1.44 5.30E-01 1.00E00 fat pad development (GO:0060613) 7 1 .69 + 1.44 5.30E-01 1.00E00 response to thyroid hormone (GO:0097066) 14 2 1.38 + 1.44 6.50E-01 1.00E00 negative regulation of autophagosome assembly (GO:1902902) 14 2 1.38 + 1.44 6.50E-01 1.00E00 positive regulation of histone H3-K27 methylation (GO:0061087) 7 1 .69 + 1.44 5.30E-01 1.00E00 positive regulation of mitotic metaphase/anaphase transition (GO:0045842) 14 2 1.38 + 1.44 6.50E-01 1.00E00 regulation of fear response (GO:1903365) 7 1 .69 + 1.44 5.30E-01 1.00E00 response to nutrient (GO:0007584) 49 7 4.84 + 1.44 3.46E-01 1.00E00 common bile duct development (GO:0061009) 7 1 .69 + 1.44 5.30E-01 1.00E00 cell differentiation involved in kidney development (GO:0061005) 28 4 2.77 + 1.44 5.28E-01 1.00E00 atrioventricular valve formation (GO:0003190) 7 1 .69 + 1.44 5.30E-01 1.00E00 epithelial cell proliferation involved in liver morphogenesis (GO:0072575) 7 1 .69 + 1.44 5.30E-01 1.00E00 hepatocyte proliferation (GO:0072574) 7 1 .69 + 1.44 5.30E-01 1.00E00 morphogenesis of an epithelial fold (GO:0060571) 14 2 1.38 + 1.44 6.50E-01 1.00E00 pyridine-containing compound metabolic process (GO:0072524) 28 4 2.77 + 1.44 5.28E-01 1.00E00 regulation of vitamin D biosynthetic process (GO:0060556) 7 1 .69 + 1.44 5.30E-01 1.00E00 type I pneumocyte differentiation (GO:0060509) 7 1 .69 + 1.44 5.30E-01 1.00E00 response to organic substance (GO:0010033) 1982 282 195.96 + 1.44 2.59E-09 4.36E-07 cellular homeostasis (GO:0019725) 675 96 66.74 + 1.44 9.78E-04 3.54E-02 localization of cell (GO:0051674) 823 117 81.37 + 1.44 2.62E-04 1.20E-02 cell motility (GO:0048870) 823 117 81.37 + 1.44 2.62E-04 1.20E-02 cellular response to extracellular stimulus (GO:0031668) 176 25 17.40 + 1.44 1.05E-01 8.99E-01 response to extracellular stimulus (GO:0009991) 275 39 27.19 + 1.43 3.64E-02 5.08E-01 regulation of lipid transport (GO:0032368) 113 16 11.17 + 1.43 1.66E-01 1.00E00 regulation of cellular ketone metabolic process (GO:0010565) 113 16 11.17 + 1.43 1.66E-01 1.00E00 regulation of anatomical structure morphogenesis (GO:0022603) 827 117 81.77 + 1.43 3.36E-04 1.46E-02 positive regulation of protein kinase activity (GO:0045860) 375 53 37.08 + 1.43 1.63E-02 3.01E-01 detection of external stimulus (GO:0009581) 92 13 9.10 + 1.43 2.29E-01 1.00E00 cellular monovalent inorganic cation homeostasis (GO:0030004) 92 13 9.10 + 1.43 2.29E-01 1.00E00 muscle system process (GO:0003012) 177 25 17.50 + 1.43 1.06E-01 8.97E-01 regulation of response to stimulus (GO:0048583) 3162 446 312.63 + 1.43 9.54E-15 3.29E-12 T cell receptor signaling pathway (GO:0050852) 78 11 7.71 + 1.43 2.63E-01 1.00E00 negative regulation of cell development (GO:0010721) 156 22 15.42 + 1.43 1.14E-01 9.37E-01 regulation of release of sequestered calcium ion into cytosol (GO:0051279) 71 10 7.02 + 1.42 3.26E-01 1.00E00 positive regulation of cell communication (GO:0010647) 1422 200 140.60 + 1.42 2.30E-06 2.03E-04 positive regulation of reproductive process (GO:2000243) 64 9 6.33 + 1.42 3.04E-01 1.00E00 negative regulation of MAP kinase activity (GO:0043407) 64 9 6.33 + 1.42 3.04E-01 1.00E00 negative regulation of innate immune response (GO:0045824) 64 9 6.33 + 1.42 3.04E-01 1.00E00 positive regulation of signaling (GO:0023056) 1430 201 141.39 + 1.42 1.97E-06 1.78E-04 blood circulation (GO:0008015) 306 43 30.25 + 1.42 3.67E-02 5.13E-01 negative regulation of small GTPase mediated signal transduction (GO:0051058) 57 8 5.64 + 1.42 3.80E-01 1.00E00 monovalent inorganic cation homeostasis (GO:0055067) 114 16 11.27 + 1.42 2.15E-01 1.00E00 forebrain cell migration (GO:0021885) 57 8 5.64 + 1.42 3.80E-01 1.00E00 regulation of protein maturation (GO:1903317) 57 8 5.64 + 1.42 3.80E-01 1.00E00 regulation of smooth muscle cell proliferation (GO:0048660) 157 22 15.52 + 1.42 1.46E-01 1.00E00 cellular iron ion homeostasis (GO:0006879) 50 7 4.94 + 1.42 3.53E-01 1.00E00 regulation of cardiac muscle contraction (GO:0055117) 50 7 4.94 + 1.42 3.53E-01 1.00E00 negative regulation of Ras protein signal transduction (GO:0046580) 50 7 4.94 + 1.42 3.53E-01 1.00E00 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002823) 50 7 4.94 + 1.42 3.53E-01 1.00E00 positive regulation of cell differentiation (GO:0045597) 779 109 77.02 + 1.42 7.16E-04 2.79E-02 positive regulation of signal transduction (GO:0009967) 1265 177 125.07 + 1.42 1.35E-05 9.62E-04 regulation of glycoprotein metabolic process (GO:1903018) 43 6 4.25 + 1.41 4.47E-01 1.00E00 chromatin silencing (GO:0006342) 43 6 4.25 + 1.41 4.47E-01 1.00E00 regulation of chondrocyte differentiation (GO:0032330) 43 6 4.25 + 1.41 4.47E-01 1.00E00 modulation of excitatory postsynaptic potential (GO:0098815) 43 6 4.25 + 1.41 4.47E-01 1.00E00 positive regulation of TOR signaling (GO:0032008) 43 6 4.25 + 1.41 4.47E-01 1.00E00 actin-mediated cell contraction (GO:0070252) 43 6 4.25 + 1.41 4.47E-01 1.00E00 regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043122) 172 24 17.01 + 1.41 1.30E-01 9.74E-01 cellular response to glucose starvation (GO:0042149) 43 6 4.25 + 1.41 4.47E-01 1.00E00 regulation of endopeptidase activity (GO:0052548) 266 37 26.30 + 1.41 5.38E-02 6.40E-01 cellular polysaccharide biosynthetic process (GO:0033692) 36 5 3.56 + 1.40 4.13E-01 1.00E00 regulation of postsynaptic membrane potential (GO:0060078) 36 5 3.56 + 1.40 4.13E-01 1.00E00 cochlea development (GO:0090102) 36 5 3.56 + 1.40 4.13E-01 1.00E00 polysaccharide biosynthetic process (GO:0000271) 36 5 3.56 + 1.40 4.13E-01 1.00E00 positive regulation of vascular associated smooth muscle cell proliferation (GO:1904707) 36 5 3.56 + 1.40 4.13E-01 1.00E00 regulation of G protein-coupled receptor signaling pathway (GO:0008277) 101 14 9.99 + 1.40 2.49E-01 1.00E00 regulation of response to stress (GO:0080134) 1097 152 108.46 + 1.40 8.84E-05 4.66E-03 synapse assembly (GO:0007416) 65 9 6.43 + 1.40 3.09E-01 1.00E00 MAPK cascade (GO:0000165) 130 18 12.85 + 1.40 1.92E-01 1.00E00 response to temperature stimulus (GO:0009266) 130 18 12.85 + 1.40 1.92E-01 1.00E00 tissue remodeling (GO:0048771) 94 13 9.29 + 1.40 2.36E-01 1.00E00 cellular response to reactive oxygen species (GO:0034614) 94 13 9.29 + 1.40 2.36E-01 1.00E00 cellular response to nutrient levels (GO:0031669) 152 21 15.03 + 1.40 1.42E-01 1.00E00 positive regulation of osteoclast differentiation (GO:0045672) 29 4 2.87 + 1.40 5.35E-01 1.00E00 regulation of regulatory T cell differentiation (GO:0045589) 29 4 2.87 + 1.40 5.35E-01 1.00E00 epithelial to mesenchymal transition (GO:0001837) 58 8 5.73 + 1.40 3.84E-01 1.00E00 positive regulation of excitatory postsynaptic potential (GO:2000463) 29 4 2.87 + 1.40 5.35E-01 1.00E00 skeletal muscle tissue regeneration (GO:0043403) 29 4 2.87 + 1.40 5.35E-01 1.00E00 oligosaccharide metabolic process (GO:0009311) 29 4 2.87 + 1.40 5.35E-01 1.00E00 focal adhesion assembly (GO:0048041) 29 4 2.87 + 1.40 5.35E-01 1.00E00 regulation of phospholipase C activity (GO:1900274) 29 4 2.87 + 1.40 5.35E-01 1.00E00 regulation of heart rate by cardiac conduction (GO:0086091) 29 4 2.87 + 1.40 5.35E-01 1.00E00 positive regulation of Rho protein signal transduction (GO:0035025) 29 4 2.87 + 1.40 5.35E-01 1.00E00 regulation of glucose import (GO:0046324) 58 8 5.73 + 1.40 3.84E-01 1.00E00 positive regulation of T cell mediated immunity (GO:0002711) 58 8 5.73 + 1.40 3.84E-01 1.00E00 signal transduction (GO:0007165) 3019 416 298.49 + 1.39 3.94E-12 9.20E-10 regulation of calcium ion transmembrane transport (GO:1903169) 138 19 13.64 + 1.39 1.62E-01 1.00E00 response to reactive oxygen species (GO:0000302) 138 19 13.64 + 1.39 1.62E-01 1.00E00 regulation of protein depolymerization (GO:1901879) 80 11 7.91 + 1.39 2.72E-01 1.00E00 cellular response to hypoxia (GO:0071456) 80 11 7.91 + 1.39 2.72E-01 1.00E00 response to glucose (GO:0009749) 80 11 7.91 + 1.39 2.72E-01 1.00E00 negative regulation of nervous system development (GO:0051961) 131 18 12.95 + 1.39 1.94E-01 1.00E00 response to tumor necrosis factor (GO:0034612) 131 18 12.95 + 1.39 1.94E-01 1.00E00 positive regulation of cell population proliferation (GO:0008284) 801 110 79.20 + 1.39 1.26E-03 4.41E-02 endoderm development (GO:0007492) 51 7 5.04 + 1.39 3.60E-01 1.00E00 ovarian follicle development (GO:0001541) 51 7 5.04 + 1.39 3.60E-01 1.00E00 forebrain generation of neurons (GO:0021872) 51 7 5.04 + 1.39 3.60E-01 1.00E00 positive regulation of insulin secretion (GO:0032024) 73 10 7.22 + 1.39 3.33E-01 1.00E00 sphingolipid metabolic process (GO:0006665) 117 16 11.57 + 1.38 2.22E-01 1.00E00 positive regulation of developmental process (GO:0051094) 1157 158 114.39 + 1.38 1.28E-04 6.40E-03 neural crest cell development (GO:0014032) 66 9 6.53 + 1.38 3.16E-01 1.00E00 protein tetramerization (GO:0051262) 66 9 6.53 + 1.38 3.16E-01 1.00E00 skeletal muscle contraction (GO:0003009) 22 3 2.18 + 1.38 4.88E-01 1.00E00 substrate-dependent cell migration (GO:0006929) 22 3 2.18 + 1.38 4.88E-01 1.00E00 regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) 22 3 2.18 + 1.38 4.88E-01 1.00E00 negative regulation of protein acetylation (GO:1901984) 22 3 2.18 + 1.38 4.88E-01 1.00E00 ERBB signaling pathway (GO:0038127) 44 6 4.35 + 1.38 4.53E-01 1.00E00 regulation of T-helper 17 type immune response (GO:2000316) 22 3 2.18 + 1.38 4.88E-01 1.00E00 negative regulation of neural precursor cell proliferation (GO:2000178) 22 3 2.18 + 1.38 4.88E-01 1.00E00 positive regulation of triglyceride metabolic process (GO:0090208) 22 3 2.18 + 1.38 4.88E-01 1.00E00 positive regulation of protein localization to cell surface (GO:2000010) 22 3 2.18 + 1.38 4.88E-01 1.00E00 regulation of release of cytochrome c from mitochondria (GO:0090199) 44 6 4.35 + 1.38 4.53E-01 1.00E00 regulation of kidney development (GO:0090183) 22 3 2.18 + 1.38 4.88E-01 1.00E00 positive regulation of cytokine production involved in inflammatory response (GO:1900017) 22 3 2.18 + 1.38 4.88E-01 1.00E00 secondary palate development (GO:0062009) 22 3 2.18 + 1.38 4.88E-01 1.00E00 cellular carbohydrate biosynthetic process (GO:0034637) 44 6 4.35 + 1.38 4.53E-01 1.00E00 chondroitin sulfate metabolic process (GO:0030204) 22 3 2.18 + 1.38 4.88E-01 1.00E00 positive regulation of activated T cell proliferation (GO:0042104) 22 3 2.18 + 1.38 4.88E-01 1.00E00 prostate gland epithelium morphogenesis (GO:0060740) 22 3 2.18 + 1.38 4.88E-01 1.00E00 negative regulation of myeloid leukocyte differentiation (GO:0002762) 44 6 4.35 + 1.38 4.53E-01 1.00E00 prostate gland morphogenesis (GO:0060512) 22 3 2.18 + 1.38 4.88E-01 1.00E00 positive regulation of transferase activity (GO:0051347) 507 69 50.13 + 1.38 1.42E-02 2.71E-01 response to chemical (GO:0042221) 2646 360 261.61 + 1.38 9.22E-10 1.69E-07 negative regulation of DNA-binding transcription factor activity (GO:0043433) 147 20 14.53 + 1.38 1.74E-01 9.74E-01 regulation of peptidyl-serine phosphorylation (GO:0033135) 125 17 12.36 + 1.38 2.36E-01 1.00E00 cell-cell adhesion via plasma-membrane adhesion molecules (GO:0098742) 125 17 12.36 + 1.38 2.36E-01 1.00E00 negative regulation of cellular response to growth factor stimulus (GO:0090288) 81 11 8.01 + 1.37 3.57E-01 1.00E00 response to hexose (GO:0009746) 81 11 8.01 + 1.37 3.57E-01 1.00E00 positive regulation of phosphorylation (GO:0042327) 723 98 71.48 + 1.37 3.89E-03 1.04E-01 glucose homeostasis (GO:0042593) 155 21 15.33 + 1.37 1.83E-01 1.00E00 positive regulation of phosphorus metabolic process (GO:0010562) 784 106 77.52 + 1.37 2.55E-03 7.53E-02 positive regulation of phosphate metabolic process (GO:0045937) 784 106 77.52 + 1.37 2.55E-03 7.51E-02 regulation of response to endoplasmic reticulum stress (GO:1905897) 74 10 7.32 + 1.37 3.37E-01 1.00E00 glycolytic process (GO:0006096) 37 5 3.66 + 1.37 4.24E-01 1.00E00 positive regulation of glucose metabolic process (GO:0010907) 37 5 3.66 + 1.37 4.24E-01 1.00E00 positive regulation of sodium ion transport (GO:0010765) 37 5 3.66 + 1.37 4.24E-01 1.00E00 positive regulation of vasoconstriction (GO:0045907) 37 5 3.66 + 1.37 4.24E-01 1.00E00 positive regulation of transport (GO:0051050) 822 111 81.27 + 1.37 2.13E-03 6.53E-02 apoptotic signaling pathway (GO:0097190) 252 34 24.92 + 1.36 9.43E-02 8.71E-01 response to stimulus (GO:0050896) 5590 754 552.69 + 1.36 2.88E-24 3.12E-21 carbohydrate homeostasis (GO:0033500) 156 21 15.42 + 1.36 1.85E-01 1.00E00 negative regulation of gene expression, epigenetic (GO:0045814) 52 7 5.14 + 1.36 4.89E-01 1.00E00 regulation of pri-miRNA transcription by RNA polymerase II (GO:1902893) 52 7 5.14 + 1.36 4.89E-01 1.00E00 cellular response to organonitrogen compound (GO:0071417) 379 51 37.47 + 1.36 4.01E-02 5.41E-01 polysaccharide metabolic process (GO:0005976) 67 9 6.62 + 1.36 4.17E-01 1.00E00 regulation of bone mineralization (GO:0030500) 67 9 6.62 + 1.36 4.17E-01 1.00E00 negative regulation of gene expression (GO:0010629) 812 109 80.28 + 1.36 2.96E-03 8.44E-02 regulation of ion transport (GO:0043269) 544 73 53.79 + 1.36 1.46E-02 2.77E-01 regulation of striated muscle cell differentiation (GO:0051153) 82 11 8.11 + 1.36 3.60E-01 1.00E00 response to monosaccharide (GO:0034284) 82 11 8.11 + 1.36 3.60E-01 1.00E00 signaling (GO:0023052) 3247 435 321.04 + 1.35 4.14E-11 8.05E-09 regulation of apoptotic signaling pathway (GO:2001233) 351 47 34.70 + 1.35 5.09E-02 6.11E-01 negative regulation of neurogenesis (GO:0050768) 127 17 12.56 + 1.35 2.40E-01 1.00E00 positive regulation of protein phosphorylation (GO:0001934) 659 88 65.16 + 1.35 8.69E-03 1.95E-01 response to organophosphorus (GO:0046683) 75 10 7.42 + 1.35 3.42E-01 1.00E00 preganglionic parasympathetic fiber development (GO:0021783) 15 2 1.48 + 1.35 6.62E-01 1.00E00 negative regulation of oxidative stress-induced cell death (GO:1903202) 45 6 4.45 + 1.35 4.59E-01 1.00E00 positive regulation of cell cycle G2/M phase transition (GO:1902751) 30 4 2.97 + 1.35 5.43E-01 1.00E00 hyperosmotic response (GO:0006972) 15 2 1.48 + 1.35 6.62E-01 1.00E00 negative regulation of intrinsic apoptotic signaling pathway (GO:2001243) 90 12 8.90 + 1.35 2.99E-01 1.00E00 regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) 15 2 1.48 + 1.35 6.62E-01 1.00E00 adenylate cyclase-modulating G protein-coupled receptor signaling pathway (GO:0007188) 135 18 13.35 + 1.35 2.54E-01 1.00E00 positive regulation of sodium ion transmembrane transporter activity (GO:2000651) 15 2 1.48 + 1.35 6.62E-01 1.00E00 establishment of pigment granule localization (GO:0051905) 15 2 1.48 + 1.35 6.62E-01 1.00E00 pigment granule transport (GO:0051904) 15 2 1.48 + 1.35 6.62E-01 1.00E00 sarcomere organization (GO:0045214) 30 4 2.97 + 1.35 5.43E-01 1.00E00 positive regulation of interleukin-13 production (GO:0032736) 15 2 1.48 + 1.35 6.62E-01 1.00E00 negative regulation of interleukin-8 production (GO:0032717) 15 2 1.48 + 1.35 6.62E-01 1.00E00 regulation of translational elongation (GO:0006448) 15 2 1.48 + 1.35 6.62E-01 1.00E00 negative regulation of peptidyl-serine phosphorylation (GO:0033137) 30 4 2.97 + 1.35 5.43E-01 1.00E00 regulation of T-helper 17 cell differentiation (GO:2000319) 15 2 1.48 + 1.35 6.62E-01 1.00E00 interferon-gamma production (GO:0032609) 15 2 1.48 + 1.35 6.62E-01 1.00E00 regulation of killing of cells of other organism (GO:0051709) 15 2 1.48 + 1.35 6.62E-01 1.00E00 cellular response to arsenic-containing substance (GO:0071243) 15 2 1.48 + 1.35 6.62E-01 1.00E00 regulation of amyloid fibril formation (GO:1905906) 15 2 1.48 + 1.35 6.62E-01 1.00E00 negative regulation of neurotransmitter transport (GO:0051589) 15 2 1.48 + 1.35 6.62E-01 1.00E00 negative regulation of cAMP-mediated signaling (GO:0043951) 15 2 1.48 + 1.35 6.62E-01 1.00E00 positive regulation by host of viral transcription (GO:0043923) 15 2 1.48 + 1.35 6.62E-01 1.00E00 negative regulation of multi-organism process (GO:0043901) 15 2 1.48 + 1.35 6.62E-01 1.00E00 regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) 15 2 1.48 + 1.35 6.62E-01 1.00E00 regulation of action potential (GO:0098900) 45 6 4.45 + 1.35 4.59E-01 1.00E00 positive regulation of neuron projection regeneration (GO:0070572) 15 2 1.48 + 1.35 6.62E-01 1.00E00 detection of chemical stimulus involved in sensory perception (GO:0050907) 15 2 1.48 + 1.35 6.62E-01 1.00E00 negative regulation of cell migration involved in sprouting angiogenesis (GO:0090051) 15 2 1.48 + 1.35 6.62E-01 1.00E00 regulation of heat generation (GO:0031650) 15 2 1.48 + 1.35 6.62E-01 1.00E00 parasympathetic nervous system development (GO:0048486) 15 2 1.48 + 1.35 6.62E-01 1.00E00 negative regulation of striated muscle cell differentiation (GO:0051154) 30 4 2.97 + 1.35 5.43E-01 1.00E00 aorta morphogenesis (GO:0035909) 30 4 2.97 + 1.35 5.43E-01 1.00E00 negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518) 15 2 1.48 + 1.35 6.62E-01 1.00E00 presynapse assembly (GO:0099054) 15 2 1.48 + 1.35 6.62E-01 1.00E00 cellular response to sterol (GO:0036315) 15 2 1.48 + 1.35 6.62E-01 1.00E00 response to oxygen radical (GO:0000305) 15 2 1.48 + 1.35 6.62E-01 1.00E00 plasma membrane phospholipid scrambling (GO:0017121) 15 2 1.48 + 1.35 6.62E-01 1.00E00 clathrin coat assembly (GO:0048268) 15 2 1.48 + 1.35 6.62E-01 1.00E00 vesicle targeting, to, from or within Golgi (GO:0048199) 15 2 1.48 + 1.35 6.62E-01 1.00E00 regulation of purine nucleotide biosynthetic process (GO:1900371) 30 4 2.97 + 1.35 5.43E-01 1.00E00 regulation of nucleotide biosynthetic process (GO:0030808) 30 4 2.97 + 1.35 5.43E-01 1.00E00 regulation of circadian sleep/wake cycle (GO:0042749) 15 2 1.48 + 1.35 6.62E-01 1.00E00 negative regulation of microtubule polymerization (GO:0031115) 15 2 1.48 + 1.35 6.62E-01 1.00E00 negative regulation of protein import (GO:1904590) 15 2 1.48 + 1.35 6.62E-01 1.00E00 regulation of execution phase of apoptosis (GO:1900117) 15 2 1.48 + 1.35 6.62E-01 1.00E00 cellular metabolic compound salvage (GO:0043094) 15 2 1.48 + 1.35 6.62E-01 1.00E00 neuroblast division (GO:0055057) 15 2 1.48 + 1.35 6.62E-01 1.00E00 purine ribonucleotide catabolic process (GO:0009154) 30 4 2.97 + 1.35 5.43E-01 1.00E00 response to auditory stimulus (GO:0010996) 15 2 1.48 + 1.35 6.62E-01 1.00E00 fatty-acyl-CoA metabolic process (GO:0035337) 15 2 1.48 + 1.35 6.62E-01 1.00E00 negative regulation of bone remodeling (GO:0046851) 15 2 1.48 + 1.35 6.62E-01 1.00E00 cellular response to angiotensin (GO:1904385) 15 2 1.48 + 1.35 6.62E-01 1.00E00 negative regulation of protein import into nucleus (GO:0042308) 15 2 1.48 + 1.35 6.62E-01 1.00E00 detection of bacterium (GO:0016045) 15 2 1.48 + 1.35 6.62E-01 1.00E00 negative regulation of histone acetylation (GO:0035067) 15 2 1.48 + 1.35 6.62E-01 1.00E00 positive regulation of Ras protein signal transduction (GO:0046579) 60 8 5.93 + 1.35 3.94E-01 1.00E00 positive regulation of humoral immune response (GO:0002922) 15 2 1.48 + 1.35 6.62E-01 1.00E00 negative regulation of immunoglobulin mediated immune response (GO:0002890) 15 2 1.48 + 1.35 6.62E-01 1.00E00 protein localization to cell surface (GO:0034394) 30 4 2.97 + 1.35 5.43E-01 1.00E00 regulation of ER to Golgi vesicle-mediated transport (GO:0060628) 15 2 1.48 + 1.35 6.62E-01 1.00E00 cell junction maintenance (GO:0034331) 30 4 2.97 + 1.35 5.43E-01 1.00E00 negative regulation of B cell mediated immunity (GO:0002713) 15 2 1.48 + 1.35 6.62E-01 1.00E00 regulation of hydrogen peroxide metabolic process (GO:0010310) 15 2 1.48 + 1.35 6.62E-01 1.00E00 negative regulation of striated muscle tissue development (GO:0045843) 15 2 1.48 + 1.35 6.62E-01 1.00E00 negative regulation of leukocyte chemotaxis (GO:0002689) 15 2 1.48 + 1.35 6.62E-01 1.00E00 cell communication (GO:0007154) 3333 444 329.54 + 1.35 4.94E-11 9.49E-09 negative regulation of programmed cell death (GO:0043069) 781 104 77.22 + 1.35 4.45E-03 1.14E-01 regulation of hydrolase activity (GO:0051336) 759 101 75.04 + 1.35 4.83E-03 1.23E-01 regulation of cysteine-type endopeptidase activity (GO:2000116) 203 27 20.07 + 1.35 1.62E-01 1.00E00 cell fate commitment (GO:0045165) 173 23 17.10 + 1.34 1.68E-01 1.00E00 response to peptide (GO:1901652) 286 38 28.28 + 1.34 9.45E-02 8.71E-01 negative regulation of phosphorylation (GO:0042326) 354 47 35.00 + 1.34 6.28E-02 7.02E-01 regulation of protein-containing complex disassembly (GO:0043244) 113 15 11.17 + 1.34 2.76E-01 1.00E00 negative regulation of apoptotic process (GO:0043066) 761 101 75.24 + 1.34 5.81E-03 1.41E-01 cellular response to oxygen levels (GO:0071453) 98 13 9.69 + 1.34 3.16E-01 1.00E00 regulation of peptide secretion (GO:0002791) 181 24 17.90 + 1.34 1.76E-01 9.84E-01 regulation of muscle cell apoptotic process (GO:0010660) 83 11 8.21 + 1.34 3.63E-01 1.00E00 negative regulation of cell death (GO:0060548) 883 117 87.30 + 1.34 2.96E-03 8.43E-02 negative regulation of cell migration (GO:0030336) 234 31 23.14 + 1.34 1.29E-01 9.69E-01 response to starvation (GO:0042594) 151 20 14.93 + 1.34 2.25E-01 1.00E00 positive regulation of small GTPase mediated signal transduction (GO:0051057) 68 9 6.72 + 1.34 4.21E-01 1.00E00 regulation of cation transmembrane transport (GO:1904062) 295 39 29.17 + 1.34 9.94E-02 8.65E-01 calcium ion transport into cytosol (GO:0060402) 53 7 5.24 + 1.34 4.93E-01 1.00E00 regulation of smooth muscle contraction (GO:0006940) 53 7 5.24 + 1.34 4.93E-01 1.00E00 regulation of actin cytoskeleton organization (GO:0032956) 318 42 31.44 + 1.34 7.67E-02 7.76E-01 sprouting angiogenesis (GO:0002040) 53 7 5.24 + 1.34 4.93E-01 1.00E00 positive regulation of cell development (GO:0010720) 303 40 29.96 + 1.34 8.57E-02 8.33E-01 response to nutrient levels (GO:0031667) 250 33 24.72 + 1.34 1.16E-01 9.44E-01 negative regulation of phosphorus metabolic process (GO:0010563) 410 54 40.54 + 1.33 4.80E-02 5.93E-01 negative regulation of phosphate metabolic process (GO:0045936) 410 54 40.54 + 1.33 4.80E-02 5.93E-01 cellular response to nitrogen compound (GO:1901699) 433 57 42.81 + 1.33 4.46E-02 5.59E-01 blood vessel remodeling (GO:0001974) 38 5 3.76 + 1.33 5.88E-01 1.00E00 ATP generation from ADP (GO:0006757) 38 5 3.76 + 1.33 5.88E-01 1.00E00 transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0007178) 152 20 15.03 + 1.33 2.27E-01 1.00E00 adult locomotory behavior (GO:0008344) 76 10 7.51 + 1.33 3.47E-01 1.00E00 regulation of endothelial cell proliferation (GO:0001936) 114 15 11.27 + 1.33 2.79E-01 1.00E00 cell population proliferation (GO:0008283) 449 59 44.39 + 1.33 4.03E-02 5.44E-01 negative regulation of molecular function (GO:0044092) 822 108 81.27 + 1.33 5.46E-03 1.35E-01 response to calcium ion (GO:0051592) 99 13 9.79 + 1.33 3.19E-01 1.00E00 regulation of wound healing (GO:0061041) 99 13 9.79 + 1.33 3.19E-01 1.00E00 regulation of hormone secretion (GO:0046883) 221 29 21.85 + 1.33 1.47E-01 1.00E00 regulation of peptide transport (GO:0090087) 183 24 18.09 + 1.33 1.80E-01 9.98E-01 positive regulation of osteoblast differentiation (GO:0045669) 61 8 6.03 + 1.33 4.01E-01 1.00E00 artery morphogenesis (GO:0048844) 61 8 6.03 + 1.33 4.01E-01 1.00E00 autophagosome assembly (GO:0000045) 61 8 6.03 + 1.33 4.01E-01 1.00E00 cardiac cell development (GO:0055006) 61 8 6.03 + 1.33 4.01E-01 1.00E00 regulation of JNK cascade (GO:0046328) 122 16 12.06 + 1.33 2.93E-01 1.00E00 regulation of cell-matrix adhesion (GO:0001952) 107 14 10.58 + 1.32 3.36E-01 1.00E00 cardiocyte differentiation (GO:0035051) 107 14 10.58 + 1.32 3.36E-01 1.00E00 positive regulation of neurogenesis (GO:0050769) 237 31 23.43 + 1.32 1.60E-01 1.00E00 regulation of protein secretion (GO:0050708) 237 31 23.43 + 1.32 1.60E-01 1.00E00 regulation of cell population proliferation (GO:0042127) 1377 180 136.15 + 1.32 3.27E-04 1.43E-02 endothelial cell differentiation (GO:0045446) 69 9 6.82 + 1.32 4.25E-01 1.00E00 regulation of myoblast differentiation (GO:0045661) 46 6 4.55 + 1.32 4.66E-01 1.00E00 positive regulation of glycoprotein metabolic process (GO:1903020) 23 3 2.27 + 1.32 5.05E-01 1.00E00 postsynaptic membrane organization (GO:0001941) 23 3 2.27 + 1.32 5.05E-01 1.00E00 glycosphingolipid biosynthetic process (GO:0006688) 23 3 2.27 + 1.32 5.05E-01 1.00E00 regulation of NMDA receptor activity (GO:2000310) 23 3 2.27 + 1.32 5.05E-01 1.00E00 cellular response to alkaloid (GO:0071312) 23 3 2.27 + 1.32 5.05E-01 1.00E00 thymic T cell selection (GO:0045061) 23 3 2.27 + 1.32 5.05E-01 1.00E00 myelin assembly (GO:0032288) 23 3 2.27 + 1.32 5.05E-01 1.00E00 negative regulation of NIK/NF-kappaB signaling (GO:1901223) 23 3 2.27 + 1.32 5.05E-01 1.00E00 negative regulation of lipid biosynthetic process (GO:0051055) 46 6 4.55 + 1.32 4.66E-01 1.00E00 cardiac muscle cell action potential involved in contraction (GO:0086002) 23 3 2.27 + 1.32 5.05E-01 1.00E00 regulation of platelet-derived growth factor receptor signaling pathway (GO:0010640) 23 3 2.27 + 1.32 5.05E-01 1.00E00 megakaryocyte differentiation (GO:0030219) 23 3 2.27 + 1.32 5.05E-01 1.00E00 cellular response to oxidative stress (GO:0034599) 184 24 18.19 + 1.32 2.21E-01 1.00E00 labyrinthine layer blood vessel development (GO:0060716) 23 3 2.27 + 1.32 5.05E-01 1.00E00 response to activity (GO:0014823) 23 3 2.27 + 1.32 5.05E-01 1.00E00 negative regulation of T cell mediated immunity (GO:0002710) 23 3 2.27 + 1.32 5.05E-01 1.00E00 digestion (GO:0007586) 46 6 4.55 + 1.32 4.66E-01 1.00E00 cardiac muscle tissue development (GO:0048738) 146 19 14.44 + 1.32 2.72E-01 1.00E00 positive regulation of cell death (GO:0010942) 592 77 58.53 + 1.32 2.28E-02 3.77E-01 regulation of sequestering of calcium ion (GO:0051282) 100 13 9.89 + 1.31 3.23E-01 1.00E00 cardiac septum development (GO:0003279) 100 13 9.89 + 1.31 3.23E-01 1.00E00 regulation of actin filament-based process (GO:0032970) 354 46 35.00 + 1.31 9.19E-02 8.53E-01 positive regulation of binding (GO:0051099) 177 23 17.50 + 1.31 2.13E-01 1.00E00 negative regulation of cellular component movement (GO:0051271) 254 33 25.11 + 1.31 1.44E-01 1.00E00 membrane lipid metabolic process (GO:0006643) 154 20 15.23 + 1.31 2.32E-01 1.00E00 regulation of cell differentiation (GO:0045595) 1310 170 129.52 + 1.31 7.02E-04 2.76E-02 telencephalon cell migration (GO:0022029) 54 7 5.34 + 1.31 4.97E-01 1.00E00 regulation of protein localization to plasma membrane (GO:1903076) 108 14 10.68 + 1.31 3.39E-01 1.00E00 ribonucleoside diphosphate metabolic process (GO:0009185) 54 7 5.34 + 1.31 4.97E-01 1.00E00 embryonic heart tube morphogenesis (GO:0003143) 54 7 5.34 + 1.31 4.97E-01 1.00E00 regulation of phosphate metabolic process (GO:0019220) 1227 159 121.32 + 1.31 1.17E-03 4.15E-02 positive regulation of ion transport (GO:0043270) 247 32 24.42 + 1.31 1.40E-01 1.00E00 regulation of reproductive process (GO:2000241) 139 18 13.74 + 1.31 2.63E-01 1.00E00 regulation of phosphorus metabolic process (GO:0051174) 1228 159 121.41 + 1.31 1.18E-03 4.16E-02 cellular component assembly involved in morphogenesis (GO:0010927) 85 11 8.40 + 1.31 3.71E-01 1.00E00 regulation of transport (GO:0051049) 1500 194 148.31 + 1.31 3.24E-04 1.42E-02 regulation of apoptotic process (GO:0042981) 1254 162 123.98 + 1.31 1.11E-03 3.95E-02 positive regulation of epidermal growth factor receptor signaling pathway (GO:0045742) 31 4 3.07 + 1.31 5.52E-01 1.00E00 cerebral cortex radially oriented cell migration (GO:0021799) 31 4 3.07 + 1.31 5.52E-01 1.00E00 positive regulation of response to wounding (GO:1903036) 62 8 6.13 + 1.31 4.07E-01 1.00E00 ventral spinal cord development (GO:0021517) 31 4 3.07 + 1.31 5.52E-01 1.00E00 NADP metabolic process (GO:0006739) 31 4 3.07 + 1.31 5.52E-01 1.00E00 protein export from nucleus (GO:0006611) 31 4 3.07 + 1.31 5.52E-01 1.00E00 cellular response to cAMP (GO:0071320) 31 4 3.07 + 1.31 5.52E-01 1.00E00 fatty acid derivative metabolic process (GO:1901568) 31 4 3.07 + 1.31 5.52E-01 1.00E00 establishment of epithelial cell polarity (GO:0090162) 31 4 3.07 + 1.31 5.52E-01 1.00E00 response to steroid hormone (GO:0048545) 124 16 12.26 + 1.31 2.99E-01 1.00E00 chaperone cofactor-dependent protein refolding (GO:0051085) 31 4 3.07 + 1.31 5.52E-01 1.00E00 positive regulation of blood circulation (GO:1903524) 31 4 3.07 + 1.31 5.52E-01 1.00E00 positive regulation of ion transmembrane transporter activity (GO:0032414) 93 12 9.20 + 1.31 3.90E-01 1.00E00 positive regulation of peptide hormone secretion (GO:0090277) 93 12 9.20 + 1.31 3.90E-01 1.00E00 activation of MAPK activity (GO:0000187) 93 12 9.20 + 1.31 3.90E-01 1.00E00 carboxylic acid biosynthetic process (GO:0046394) 186 24 18.39 + 1.31 2.23E-01 1.00E00 regulation of programmed cell death (GO:0043067) 1287 166 127.25 + 1.30 1.07E-03 3.82E-02 regulation of blood circulation (GO:1903522) 194 25 19.18 + 1.30 2.33E-01 1.00E00 regulation of phosphorylation (GO:0042325) 1102 142 108.96 + 1.30 2.74E-03 7.92E-02 regulation of protein localization to cell periphery (GO:1904375) 132 17 13.05 + 1.30 3.12E-01 1.00E00 stem cell development (GO:0048864) 70 9 6.92 + 1.30 4.29E-01 1.00E00 regulation of Ras protein signal transduction (GO:0046578) 179 23 17.70 + 1.30 2.17E-01 1.00E00 regulation of cell death (GO:0010941) 1425 183 140.89 + 1.30 6.67E-04 2.64E-02 negative regulation of lipid localization (GO:1905953) 39 5 3.86 + 1.30 5.93E-01 1.00E00 regulation of fibroblast migration (GO:0010762) 39 5 3.86 + 1.30 5.93E-01 1.00E00 regulation of Rho protein signal transduction (GO:0035023) 78 10 7.71 + 1.30 4.52E-01 1.00E00 learning or memory (GO:0007611) 234 30 23.14 + 1.30 1.92E-01 1.00E00 positive regulation of mitotic nuclear division (GO:0045840) 39 5 3.86 + 1.30 5.93E-01 1.00E00 endothelium development (GO:0003158) 78 10 7.71 + 1.30 4.52E-01 1.00E00 negative regulation of response to stimulus (GO:0048585) 1374 176 135.85 + 1.30 9.09E-04 3.35E-02 cellular response to external stimulus (GO:0071496) 203 26 20.07 + 1.30 2.01E-01 1.00E00 stem cell differentiation (GO:0048863) 125 16 12.36 + 1.29 3.02E-01 1.00E00 regulation of MAP kinase activity (GO:0043405) 250 32 24.72 + 1.29 1.71E-01 1.00E00 regulation of protein phosphorylation (GO:0001932) 985 126 97.39 + 1.29 6.52E-03 1.56E-01 positive regulation of programmed cell death (GO:0043068) 532 68 52.60 + 1.29 4.92E-02 6.03E-01 regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043281) 180 23 17.80 + 1.29 2.65E-01 1.00E00 regulation of localization (GO:0032879) 2349 300 232.25 + 1.29 8.24E-06 6.47E-04 regulation of transmembrane transport (GO:0034762) 462 59 45.68 + 1.29 6.18E-02 6.98E-01 single fertilization (GO:0007338) 94 12 9.29 + 1.29 3.93E-01 1.00E00 regulation of gluconeogenesis (GO:0006111) 47 6 4.65 + 1.29 4.74E-01 1.00E00 embryonic pattern specification (GO:0009880) 47 6 4.65 + 1.29 4.74E-01 1.00E00 skeletal muscle cell differentiation (GO:0035914) 47 6 4.65 + 1.29 4.74E-01 1.00E00 negative regulation of wound healing (GO:0061045) 47 6 4.65 + 1.29 4.74E-01 1.00E00 vasculature development (GO:0001944) 486 62 48.05 + 1.29 5.75E-02 6.67E-01 regulation of intracellular signal transduction (GO:1902531) 1373 175 135.75 + 1.29 1.25E-03 4.38E-02 negative regulation of protein phosphorylation (GO:0001933) 314 40 31.05 + 1.29 1.32E-01 9.85E-01 regulation of developmental process (GO:0050793) 2073 264 204.96 + 1.29 4.72E-05 2.82E-03 chondrocyte differentiation (GO:0002062) 55 7 5.44 + 1.29 5.02E-01 1.00E00 aorta development (GO:0035904) 55 7 5.44 + 1.29 5.02E-01 1.00E00 cardiac muscle cell development (GO:0055013) 55 7 5.44 + 1.29 5.02E-01 1.00E00 pancreas development (GO:0031016) 55 7 5.44 + 1.29 5.02E-01 1.00E00 negative regulation of lymphocyte mediated immunity (GO:0002707) 55 7 5.44 + 1.29 5.02E-01 1.00E00 regulation of cartilage development (GO:0061035) 55 7 5.44 + 1.29 5.02E-01 1.00E00 positive regulation of apoptotic process (GO:0043065) 519 66 51.31 + 1.29 5.53E-02 6.43E-01 regulation of striated muscle contraction (GO:0006942) 63 8 6.23 + 1.28 5.29E-01 1.00E00 exocytosis (GO:0006887) 189 24 18.69 + 1.28 2.29E-01 1.00E00 circadian regulation of gene expression (GO:0032922) 63 8 6.23 + 1.28 5.29E-01 1.00E00 regulation of cell-substrate junction organization (GO:0150116) 63 8 6.23 + 1.28 5.29E-01 1.00E00 positive regulation of protein localization to cell periphery (GO:1904377) 63 8 6.23 + 1.28 5.29E-01 1.00E00 neural crest cell differentiation (GO:0014033) 71 9 7.02 + 1.28 4.34E-01 1.00E00 negative regulation of cell motility (GO:2000146) 245 31 24.22 + 1.28 2.02E-01 1.00E00 supramolecular fiber organization (GO:0097435) 427 54 42.22 + 1.28 8.90E-02 8.39E-01 negative regulation of response to biotic stimulus (GO:0002832) 95 12 9.39 + 1.28 3.96E-01 1.00E00 positive regulation of calcium ion transport (GO:0051928) 111 14 10.97 + 1.28 3.49E-01 1.00E00 anion transmembrane transport (GO:0098656) 127 16 12.56 + 1.27 3.76E-01 1.00E00 positive regulation of molecular function (GO:0044093) 1286 162 127.15 + 1.27 2.84E-03 8.14E-02 blood vessel development (GO:0001568) 461 58 45.58 + 1.27 8.58E-02 8.31E-01 regulation of system process (GO:0044057) 469 59 46.37 + 1.27 8.83E-02 8.34E-01 regulation of stress-activated MAPK cascade (GO:0032872) 167 21 16.51 + 1.27 3.03E-01 1.00E00 negative regulation of cell growth (GO:0030308) 167 21 16.51 + 1.27 3.03E-01 1.00E00 response to decreased oxygen levels (GO:0036293) 175 22 17.30 + 1.27 2.61E-01 1.00E00 regulation of cell-substrate adhesion (GO:0010810) 191 24 18.88 + 1.27 2.79E-01 1.00E00 organic acid biosynthetic process (GO:0016053) 191 24 18.88 + 1.27 2.79E-01 1.00E00 regulation of hormone levels (GO:0010817) 390 49 38.56 + 1.27 1.08E-01 9.07E-01 G protein-coupled receptor signaling pathway (GO:0007186) 502 63 49.63 + 1.27 7.24E-02 7.40E-01 ion transport (GO:0006811) 789 99 78.01 + 1.27 2.54E-02 4.04E-01 positive regulation of nervous system development (GO:0051962) 279 35 27.59 + 1.27 1.94E-01 1.00E00 response to oxidative stress (GO:0006979) 303 38 29.96 + 1.27 1.79E-01 9.97E-01 regulation of protein kinase activity (GO:0045859) 591 74 58.43 + 1.27 5.27E-02 6.29E-01 regulation of hexokinase activity (GO:1903299) 8 1 .79 + 1.26 5.72E-01 1.00E00 phospholipid efflux (GO:0033700) 8 1 .79 + 1.26 5.72E-01 1.00E00 aldehyde biosynthetic process (GO:0046184) 8 1 .79 + 1.26 5.72E-01 1.00E00 cellular response to amino acid starvation (GO:0034198) 40 5 3.95 + 1.26 5.98E-01 1.00E00 regulation of establishment of endothelial barrier (GO:1903140) 16 2 1.58 + 1.26 6.74E-01 1.00E00 segment specification (GO:0007379) 8 1 .79 + 1.26 5.72E-01 1.00E00 positive regulation of mammary gland epithelial cell proliferation (GO:0033601) 8 1 .79 + 1.26 5.72E-01 1.00E00 facial nerve structural organization (GO:0021612) 8 1 .79 + 1.26 5.72E-01 1.00E00 regulation of synaptic vesicle clustering (GO:2000807) 8 1 .79 + 1.26 5.72E-01 1.00E00 cellular response to epinephrine stimulus (GO:0071872) 8 1 .79 + 1.26 5.72E-01 1.00E00 response to epinephrine (GO:0071871) 8 1 .79 + 1.26 5.72E-01 1.00E00 negative regulation of cell differentiation (GO:0045596) 552 69 54.58 + 1.26 6.30E-02 7.04E-01 regulation of epithelial cell proliferation involved in lung morphogenesis (GO:2000794) 8 1 .79 + 1.26 5.72E-01 1.00E00 negative regulation of T cell mediated cytotoxicity (GO:0001915) 8 1 .79 + 1.26 5.72E-01 1.00E00 embryonic skeletal joint morphogenesis (GO:0060272) 8 1 .79 + 1.26 5.72E-01 1.00E00 negative regulation of cardiac muscle cell differentiation (GO:2000726) 8 1 .79 + 1.26 5.72E-01 1.00E00 basement membrane organization (GO:0071711) 24 3 2.37 + 1.26 7.31E-01 1.00E00 bone resorption (GO:0045453) 24 3 2.37 + 1.26 7.31E-01 1.00E00 epidermal growth factor receptor signaling pathway (GO:0007173) 40 5 3.95 + 1.26 5.98E-01 1.00E00 regulation of nephron tubule epithelial cell differentiation (GO:0072182) 8 1 .79 + 1.26 5.72E-01 1.00E00 negative regulation of transcription regulatory region DNA binding (GO:2000678) 16 2 1.58 + 1.26 6.74E-01 1.00E00 cell proliferation involved in kidney development (GO:0072111) 8 1 .79 + 1.26 5.72E-01 1.00E00 embryonic process involved in female pregnancy (GO:0060136) 8 1 .79 + 1.26 5.72E-01 1.00E00 sphingosine metabolic process (GO:0006670) 16 2 1.58 + 1.26 6.74E-01 1.00E00 leukocyte chemotaxis involved in inflammatory response (GO:0002232) 8 1 .79 + 1.26 5.72E-01 1.00E00 positive regulation of integrin-mediated signaling pathway (GO:2001046) 8 1 .79 + 1.26 5.72E-01 1.00E00 vagina development (GO:0060068) 8 1 .79 + 1.26 5.72E-01 1.00E00 regulation of establishment or maintenance of cell polarity (GO:0032878) 24 3 2.37 + 1.26 7.31E-01 1.00E00 neurofilament cytoskeleton organization (GO:0060052) 8 1 .79 + 1.26 5.72E-01 1.00E00 positive regulation of synaptic transmission, glutamatergic (GO:0051968) 24 3 2.37 + 1.26 7.31E-01 1.00E00 retinoic acid biosynthetic process (GO:0002138) 8 1 .79 + 1.26 5.72E-01 1.00E00 catecholamine transport (GO:0051937) 8 1 .79 + 1.26 5.72E-01 1.00E00 regulation of hepatic stellate cell activation (GO:2000489) 8 1 .79 + 1.26 5.72E-01 1.00E00 pre-replicative complex assembly involved in cell cycle DNA replication (GO:1902299) 8 1 .79 + 1.26 5.72E-01 1.00E00 regulation of monooxygenase activity (GO:0032768) 40 5 3.95 + 1.26 5.98E-01 1.00E00 p38MAPK cascade (GO:0038066) 8 1 .79 + 1.26 5.72E-01 1.00E00 regulation of the force of heart contraction (GO:0002026) 24 3 2.37 + 1.26 7.31E-01 1.00E00 regulation of blood volume by renin-angiotensin (GO:0002016) 8 1 .79 + 1.26 5.72E-01 1.00E00 negative regulation of interferon-beta production (GO:0032688) 16 2 1.58 + 1.26 6.74E-01 1.00E00 DNA catabolic process (GO:0006308) 16 2 1.58 + 1.26 6.74E-01 1.00E00 calcium ion export (GO:1901660) 8 1 .79 + 1.26 5.72E-01 1.00E00 double-strand break repair via synthesis-dependent strand annealing (GO:0045003) 8 1 .79 + 1.26 5.72E-01 1.00E00 basement membrane assembly (GO:0070831) 8 1 .79 + 1.26 5.72E-01 1.00E00 relaxation of smooth muscle (GO:0044557) 8 1 .79 + 1.26 5.72E-01 1.00E00 response to salt (GO:1902074) 8 1 .79 + 1.26 5.72E-01 1.00E00 protein localization to axon (GO:0099612) 8 1 .79 + 1.26 5.72E-01 1.00E00 pre-replicative complex assembly involved in nuclear cell cycle DNA replication (GO:0006267) 8 1 .79 + 1.26 5.72E-01 1.00E00 establishment of Golgi localization (GO:0051683) 8 1 .79 + 1.26 5.72E-01 1.00E00 cellular response to electrical stimulus (GO:0071257) 8 1 .79 + 1.26 5.72E-01 1.00E00 regulation of endothelial cell development (GO:1901550) 16 2 1.58 + 1.26 6.74E-01 1.00E00 positive regulation of brown fat cell differentiation (GO:0090336) 16 2 1.58 + 1.26 6.74E-01 1.00E00 histone H3-K27 methylation (GO:0070734) 8 1 .79 + 1.26 5.72E-01 1.00E00 peptidyl-cysteine modification (GO:0018198) 32 4 3.16 + 1.26 5.61E-01 1.00E00 modulation by symbiont of host programmed cell death (GO:0052040) 8 1 .79 + 1.26 5.72E-01 1.00E00 IMP biosynthetic process (GO:0006188) 8 1 .79 + 1.26 5.72E-01 1.00E00 positive regulation of embryonic development (GO:0040019) 16 2 1.58 + 1.26 6.74E-01 1.00E00 negative regulation of locomotion (GO:0040013) 272 34 26.89 + 1.26 1.90E-01 1.00E00 ossification involved in bone maturation (GO:0043931) 16 2 1.58 + 1.26 6.74E-01 1.00E00 positive regulation of chromosome separation (GO:1905820) 16 2 1.58 + 1.26 6.74E-01 1.00E00 regulation of fibroblast growth factor production (GO:0090270) 8 1 .79 + 1.26 5.72E-01 1.00E00 regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) 16 2 1.58 + 1.26 6.74E-01 1.00E00 negative regulation of lipid kinase activity (GO:0090219) 8 1 .79 + 1.26 5.72E-01 1.00E00 pigment granule organization (GO:0048753) 16 2 1.58 + 1.26 6.74E-01 1.00E00 semicircular canal morphogenesis (GO:0048752) 8 1 .79 + 1.26 5.72E-01 1.00E00 dendrite arborization (GO:0140059) 8 1 .79 + 1.26 5.72E-01 1.00E00 regulation of skeletal muscle fiber development (GO:0048742) 8 1 .79 + 1.26 5.72E-01 1.00E00 sebaceous gland development (GO:0048733) 8 1 .79 + 1.26 5.72E-01 1.00E00 negative regulation of cell-cell adhesion mediated by cadherin (GO:2000048) 8 1 .79 + 1.26 5.72E-01 1.00E00 glycerol-3-phosphate metabolic process (GO:0006072) 8 1 .79 + 1.26 5.72E-01 1.00E00 uronic acid metabolic process (GO:0006063) 8 1 .79 + 1.26 5.72E-01 1.00E00 cellular response to insulin-like growth factor stimulus (GO:1990314) 8 1 .79 + 1.26 5.72E-01 1.00E00 mitochondrion morphogenesis (GO:0070584) 24 3 2.37 + 1.26 7.31E-01 1.00E00 negative regulation of collateral sprouting (GO:0048671) 8 1 .79 + 1.26 5.72E-01 1.00E00 collateral sprouting (GO:0048668) 8 1 .79 + 1.26 5.72E-01 1.00E00 cellular polysaccharide metabolic process (GO:0044264) 64 8 6.33 + 1.26 5.32E-01 1.00E00 diapedesis (GO:0050904) 8 1 .79 + 1.26 5.72E-01 1.00E00 regulation of artery morphogenesis (GO:1905651) 8 1 .79 + 1.26 5.72E-01 1.00E00 flavonoid metabolic process (GO:0009812) 8 1 .79 + 1.26 5.72E-01 1.00E00 positive regulation of protein kinase C signaling (GO:0090037) 8 1 .79 + 1.26 5.72E-01 1.00E00 positive regulation of steroid hormone biosynthetic process (GO:0090031) 8 1 .79 + 1.26 5.72E-01 1.00E00 L-glutamate import across plasma membrane (GO:0098712) 8 1 .79 + 1.26 5.72E-01 1.00E00 synaptic vesicle membrane organization (GO:0048499) 16 2 1.58 + 1.26 6.74E-01 1.00E00 endodermal cell differentiation (GO:0035987) 16 2 1.58 + 1.26 6.74E-01 1.00E00 autophagy of mitochondrion (GO:0000422) 40 5 3.95 + 1.26 5.98E-01 1.00E00 regulation of kinase activity (GO:0043549) 672 84 66.44 + 1.26 4.33E-02 5.45E-01 hepoxilin biosynthetic process (GO:0051122) 8 1 .79 + 1.26 5.72E-01 1.00E00 hepoxilin metabolic process (GO:0051121) 8 1 .79 + 1.26 5.72E-01 1.00E00 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway (GO:1901029) 8 1 .79 + 1.26 5.72E-01 1.00E00 retinoic acid receptor signaling pathway (GO:0048384) 16 2 1.58 + 1.26 6.74E-01 1.00E00 pre-replicative complex assembly (GO:0036388) 8 1 .79 + 1.26 5.72E-01 1.00E00 negative regulation of T cell apoptotic process (GO:0070233) 24 3 2.37 + 1.26 7.31E-01 1.00E00 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (GO:0035872) 8 1 .79 + 1.26 5.72E-01 1.00E00 protein K11-linked deubiquitination (GO:0035871) 8 1 .79 + 1.26 5.72E-01 1.00E00 amyloid precursor protein catabolic process (GO:0042987) 16 2 1.58 + 1.26 6.74E-01 1.00E00 peptidyl-serine autophosphorylation (GO:0036289) 8 1 .79 + 1.26 5.72E-01 1.00E00 positive regulation of aspartic-type peptidase activity (GO:1905247) 8 1 .79 + 1.26 5.72E-01 1.00E00 hematopoietic stem cell migration (GO:0035701) 8 1 .79 + 1.26 5.72E-01 1.00E00 response to cold (GO:0009409) 32 4 3.16 + 1.26 5.61E-01 1.00E00 regulation of core promoter binding (GO:1904796) 8 1 .79 + 1.26 5.72E-01 1.00E00 positive regulation of purine nucleotide biosynthetic process (GO:1900373) 16 2 1.58 + 1.26 6.74E-01 1.00E00 positive regulation of nucleotide biosynthetic process (GO:0030810) 16 2 1.58 + 1.26 6.74E-01 1.00E00 midbody abscission (GO:0061952) 16 2 1.58 + 1.26 6.74E-01 1.00E00 oligopeptide transmembrane transport (GO:0035672) 8 1 .79 + 1.26 5.72E-01 1.00E00 autophagosome-lysosome fusion (GO:0061909) 8 1 .79 + 1.26 5.72E-01 1.00E00 posttranslational protein targeting to membrane, translocation (GO:0031204) 8 1 .79 + 1.26 5.72E-01 1.00E00 positive regulation of developmental pigmentation (GO:0048087) 8 1 .79 + 1.26 5.72E-01 1.00E00 very long-chain fatty acid catabolic process (GO:0042760) 8 1 .79 + 1.26 5.72E-01 1.00E00 positive regulation of ubiquitin protein ligase activity (GO:1904668) 8 1 .79 + 1.26 5.72E-01 1.00E00 positive regulation of circadian rhythm (GO:0042753) 16 2 1.58 + 1.26 6.74E-01 1.00E00 sequestering of extracellular ligand from receptor (GO:0035581) 8 1 .79 + 1.26 5.72E-01 1.00E00 negative regulation of guanyl-nucleotide exchange factor activity (GO:1905098) 8 1 .79 + 1.26 5.72E-01 1.00E00 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) 16 2 1.58 + 1.26 6.74E-01 1.00E00 phosphate ion homeostasis (GO:0055062) 8 1 .79 + 1.26 5.72E-01 1.00E00 mitochondrion disassembly (GO:0061726) 40 5 3.95 + 1.26 5.98E-01 1.00E00 cardiac muscle cell differentiation (GO:0055007) 80 10 7.91 + 1.26 4.59E-01 1.00E00 histone-serine phosphorylation (GO:0035404) 8 1 .79 + 1.26 5.72E-01 1.00E00 peptidyl-lysine deacetylation (GO:0034983) 8 1 .79 + 1.26 5.72E-01 1.00E00 nuclear body organization (GO:0030575) 16 2 1.58 + 1.26 6.74E-01 1.00E00 positive regulation of xenophagy (GO:1904417) 8 1 .79 + 1.26 5.72E-01 1.00E00 regulation of xenophagy (GO:1904415) 8 1 .79 + 1.26 5.72E-01 1.00E00 AV node cell to bundle of His cell communication (GO:0086067) 8 1 .79 + 1.26 5.72E-01 1.00E00 regulation of phosphatidylcholine metabolic process (GO:0150172) 8 1 .79 + 1.26 5.72E-01 1.00E00 regulation of odontogenesis of dentin-containing tooth (GO:0042487) 8 1 .79 + 1.26 5.72E-01 1.00E00 outer ear morphogenesis (GO:0042473) 8 1 .79 + 1.26 5.72E-01 1.00E00 positive regulation of steroid biosynthetic process (GO:0010893) 24 3 2.37 + 1.26 7.31E-01 1.00E00 negative regulation of lipid storage (GO:0010888) 16 2 1.58 + 1.26 6.74E-01 1.00E00 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO:0010881) 8 1 .79 + 1.26 5.72E-01 1.00E00 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) 16 2 1.58 + 1.26 6.74E-01 1.00E00 regulation of complement activation, classical pathway (GO:0030450) 8 1 .79 + 1.26 5.72E-01 1.00E00 diterpenoid biosynthetic process (GO:0016102) 8 1 .79 + 1.26 5.72E-01 1.00E00 ectopic germ cell programmed cell death (GO:0035234) 8 1 .79 + 1.26 5.72E-01 1.00E00 fructose 1,6-bisphosphate metabolic process (GO:0030388) 8 1 .79 + 1.26 5.72E-01 1.00E00 carbohydrate biosynthetic process (GO:0016051) 80 10 7.91 + 1.26 4.59E-01 1.00E00 regulation of nitric oxide mediated signal transduction (GO:0010749) 8 1 .79 + 1.26 5.72E-01 1.00E00 negative regulation of macrophage derived foam cell differentiation (GO:0010745) 8 1 .79 + 1.26 5.72E-01 1.00E00 negative regulation of establishment of protein localization to mitochondrion (GO:1903748) 8 1 .79 + 1.26 5.72E-01 1.00E00 cardiac pacemaker cell differentiation (GO:0060920) 8 1 .79 + 1.26 5.72E-01 1.00E00 cardiac cell fate commitment (GO:0060911) 8 1 .79 + 1.26 5.72E-01 1.00E00 purine nucleoside metabolic process (GO:0042278) 24 3 2.37 + 1.26 7.31E-01 1.00E00 regulation of natural killer cell mediated cytotoxicity (GO:0042269) 40 5 3.95 + 1.26 5.98E-01 1.00E00 nucleobase-containing small molecule catabolic process (GO:0034656) 16 2 1.58 + 1.26 6.74E-01 1.00E00 digestive system process (GO:0022600) 40 5 3.95 + 1.26 5.98E-01 1.00E00 negative regulation of mitochondrial fusion (GO:0010637) 8 1 .79 + 1.26 5.72E-01 1.00E00 heparin metabolic process (GO:0030202) 8 1 .79 + 1.26 5.72E-01 1.00E00 blood vessel endothelial cell differentiation (GO:0060837) 8 1 .79 + 1.26 5.72E-01 1.00E00 axis elongation (GO:0003401) 24 3 2.37 + 1.26 7.31E-01 1.00E00 development of secondary female sexual characteristics (GO:0046543) 8 1 .79 + 1.26 5.72E-01 1.00E00 endothelial cell activation (GO:0042118) 8 1 .79 + 1.26 5.72E-01 1.00E00 negative regulation of smooth muscle cell migration (GO:0014912) 24 3 2.37 + 1.26 7.31E-01 1.00E00 smooth muscle cell migration (GO:0014909) 8 1 .79 + 1.26 5.72E-01 1.00E00 regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) 16 2 1.58 + 1.26 6.74E-01 1.00E00 regulation of mitotic spindle checkpoint (GO:1903504) 16 2 1.58 + 1.26 6.74E-01 1.00E00 sphingosine-1-phosphate receptor signaling pathway (GO:0003376) 8 1 .79 + 1.26 5.72E-01 1.00E00 cell differentiation involved in embryonic placenta development (GO:0060706) 24 3 2.37 + 1.26 7.31E-01 1.00E00 peptide hormone secretion (GO:0030072) 48 6 4.75 + 1.26 6.30E-01 1.00E00 vascular associated smooth muscle contraction (GO:0014829) 16 2 1.58 + 1.26 6.74E-01 1.00E00 postsynaptic density organization (GO:0097106) 16 2 1.58 + 1.26 6.74E-01 1.00E00 postsynaptic membrane assembly (GO:0097104) 8 1 .79 + 1.26 5.72E-01 1.00E00 negative regulation of cell maturation (GO:1903430) 8 1 .79 + 1.26 5.72E-01 1.00E00 placenta blood vessel development (GO:0060674) 32 4 3.16 + 1.26 5.61E-01 1.00E00 positive regulation of protein localization to early endosome (GO:1902966) 8 1 .79 + 1.26 5.72E-01 1.00E00 regulation of protein localization to early endosome (GO:1902965) 8 1 .79 + 1.26 5.72E-01 1.00E00 cardiac ventricle formation (GO:0003211) 8 1 .79 + 1.26 5.72E-01 1.00E00 adherens junction maintenance (GO:0034334) 8 1 .79 + 1.26 5.72E-01 1.00E00 negative regulation of smoothened signaling pathway (GO:0045879) 32 4 3.16 + 1.26 5.61E-01 1.00E00 negative regulation of T cell cytokine production (GO:0002725) 8 1 .79 + 1.26 5.72E-01 1.00E00 glucuronate metabolic process (GO:0019585) 8 1 .79 + 1.26 5.72E-01 1.00E00 pyridine-containing compound catabolic process (GO:0072526) 8 1 .79 + 1.26 5.72E-01 1.00E00 trivalent inorganic anion homeostasis (GO:0072506) 8 1 .79 + 1.26 5.72E-01 1.00E00 regulation of protein binding (GO:0043393) 200 25 19.77 + 1.26 2.89E-01 1.00E00 response to alcohol (GO:0097305) 112 14 11.07 + 1.26 4.32E-01 1.00E00 negative regulation of epithelial cell migration (GO:0010633) 56 7 5.54 + 1.26 5.08E-01 1.00E00 artery development (GO:0060840) 88 11 8.70 + 1.26 4.78E-01 1.00E00 negative regulation of cell population proliferation (GO:0008285) 586 73 57.94 + 1.26 6.05E-02 6.86E-01 metal ion transport (GO:0030001) 241 30 23.83 + 1.26 2.38E-01 1.00E00 regulation of transmembrane transporter activity (GO:0022898) 217 27 21.46 + 1.26 2.59E-01 1.00E00 activation of protein kinase activity (GO:0032147) 193 24 19.08 + 1.26 2.82E-01 1.00E00 response to hypoxia (GO:0001666) 169 21 16.71 + 1.26 3.07E-01 1.00E00 cellular response to stimulus (GO:0051716) 4429 549 437.90 + 1.25 3.67E-09 5.93E-07 negative regulation of developmental process (GO:0051093) 775 96 76.63 + 1.25 3.82E-02 5.30E-01 organophosphate ester transport (GO:0015748) 97 12 9.59 + 1.25 4.04E-01 1.00E00 regulation of stress-activated protein kinase signaling cascade (GO:0070302) 170 21 16.81 + 1.25 3.10E-01 1.00E00 response to heat (GO:0009408) 81 10 8.01 + 1.25 4.63E-01 1.00E00 cation transport (GO:0006812) 559 69 55.27 + 1.25 8.73E-02 8.27E-01 positive regulation of protein serine/threonine kinase activity (GO:0071902) 235 29 23.23 + 1.25 2.77E-01 1.00E00 regulation of heart rate (GO:0002027) 73 9 7.22 + 1.25 5.59E-01 1.00E00 cellular response to chemical stress (GO:0062197) 219 27 21.65 + 1.25 2.62E-01 1.00E00 anion transport (GO:0006820) 276 34 27.29 + 1.25 2.28E-01 1.00E00 cardiac septum morphogenesis (GO:0060411) 65 8 6.43 + 1.24 5.36E-01 1.00E00 positive regulation of cation transmembrane transport (GO:1904064) 130 16 12.85 + 1.24 3.83E-01 1.00E00 ossification (GO:0001503) 187 23 18.49 + 1.24 3.30E-01 1.00E00 regulation of generation of precursor metabolites and energy (GO:0043467) 122 15 12.06 + 1.24 4.51E-01 1.00E00 positive regulation of protein localization to plasma membrane (GO:1903078) 57 7 5.64 + 1.24 5.14E-01 1.00E00 purine ribonucleoside triphosphate metabolic process (GO:0009205) 57 7 5.64 + 1.24 5.14E-01 1.00E00 negative regulation of protein serine/threonine kinase activity (GO:0071901) 106 13 10.48 + 1.24 4.22E-01 1.00E00 regulation of signal transduction (GO:0009966) 2376 291 234.92 + 1.24 2.13E-04 1.00E-02 positive regulation of axon extension (GO:0045773) 49 6 4.84 + 1.24 6.33E-01 1.00E00 cell fate specification (GO:0001708) 49 6 4.84 + 1.24 6.33E-01 1.00E00 positive regulation of ion transmembrane transport (GO:0034767) 147 18 14.53 + 1.24 4.10E-01 1.00E00 negative regulation of muscle cell apoptotic process (GO:0010656) 49 6 4.84 + 1.24 6.33E-01 1.00E00 peptide secretion (GO:0002790) 49 6 4.84 + 1.24 6.33E-01 1.00E00 regulation of dendritic spine morphogenesis (GO:0061001) 49 6 4.84 + 1.24 6.33E-01 1.00E00 regulation of cell development (GO:0060284) 474 58 46.87 + 1.24 1.23E-01 9.86E-01 movement of cell or subcellular component (GO:0006928) 1161 142 114.79 + 1.24 1.53E-02 2.86E-01 positive regulation of MAP kinase activity (GO:0043406) 180 22 17.80 + 1.24 3.23E-01 1.00E00 regulation of synaptic plasticity (GO:0048167) 180 22 17.80 + 1.24 3.23E-01 1.00E00 response to endogenous stimulus (GO:0009719) 884 108 87.40 + 1.24 3.41E-02 4.90E-01 negative regulation of growth (GO:0045926) 221 27 21.85 + 1.24 3.13E-01 1.00E00 cognition (GO:0050890) 262 32 25.90 + 1.24 2.57E-01 1.00E00 regulation of catalytic activity (GO:0050790) 1532 187 151.47 + 1.23 4.94E-03 1.24E-01 export from cell (GO:0140352) 336 41 33.22 + 1.23 2.02E-01 1.00E00 membrane assembly (GO:0071709) 41 5 4.05 + 1.23 6.04E-01 1.00E00 regulation of multi-organism process (GO:0043900) 41 5 4.05 + 1.23 6.04E-01 1.00E00 neuron fate commitment (GO:0048663) 41 5 4.05 + 1.23 6.04E-01 1.00E00 purine ribonucleoside triphosphate biosynthetic process (GO:0009206) 41 5 4.05 + 1.23 6.04E-01 1.00E00 negative regulation of response to endoplasmic reticulum stress (GO:1903573) 41 5 4.05 + 1.23 6.04E-01 1.00E00 forebrain neuron differentiation (GO:0021879) 41 5 4.05 + 1.23 6.04E-01 1.00E00 morphogenesis of a branching epithelium (GO:0061138) 156 19 15.42 + 1.23 3.54E-01 1.00E00 positive regulation of cell killing (GO:0031343) 74 9 7.32 + 1.23 5.61E-01 1.00E00 sphingolipid biosynthetic process (GO:0030148) 74 9 7.32 + 1.23 5.61E-01 1.00E00 cardiac chamber development (GO:0003205) 148 18 14.63 + 1.23 4.12E-01 1.00E00 positive regulation of catalytic activity (GO:0043085) 938 114 92.74 + 1.23 3.42E-02 4.90E-01 regulation of cell killing (GO:0031341) 107 13 10.58 + 1.23 4.26E-01 1.00E00 angiogenesis (GO:0001525) 280 34 27.68 + 1.23 2.72E-01 1.00E00 negative regulation of calcium ion transmembrane transport (GO:1903170) 33 4 3.26 + 1.23 5.71E-01 1.00E00 regulation of actin filament-based movement (GO:1903115) 33 4 3.26 + 1.23 5.71E-01 1.00E00 nucleus localization (GO:0051647) 33 4 3.26 + 1.23 5.71E-01 1.00E00 regulation of protein targeting to membrane (GO:0090313) 33 4 3.26 + 1.23 5.71E-01 1.00E00 purine nucleotide catabolic process (GO:0006195) 33 4 3.26 + 1.23 5.71E-01 1.00E00 positive regulation of ERBB signaling pathway (GO:1901186) 33 4 3.26 + 1.23 5.71E-01 1.00E00 negative regulation of fibroblast proliferation (GO:0048147) 33 4 3.26 + 1.23 5.71E-01 1.00E00 digestive system development (GO:0055123) 99 12 9.79 + 1.23 5.03E-01 1.00E00 ventricular septum development (GO:0003281) 66 8 6.53 + 1.23 5.41E-01 1.00E00 neuron recognition (GO:0008038) 33 4 3.26 + 1.23 5.71E-01 1.00E00 response to oxygen levels (GO:0070482) 190 23 18.79 + 1.22 3.35E-01 1.00E00 embryonic placenta development (GO:0001892) 91 11 9.00 + 1.22 4.88E-01 1.00E00 gland morphogenesis (GO:0022612) 91 11 9.00 + 1.22 4.88E-01 1.00E00 negative regulation of intracellular signal transduction (GO:1902532) 464 56 45.88 + 1.22 1.60E-01 1.00E00 regulation of focal adhesion assembly (GO:0051893) 58 7 5.73 + 1.22 5.20E-01 1.00E00 cellular response to amino acid stimulus (GO:0071230) 58 7 5.73 + 1.22 5.20E-01 1.00E00 regulation of cell-substrate junction assembly (GO:0090109) 58 7 5.73 + 1.22 5.20E-01 1.00E00 endothelial cell migration (GO:0043542) 58 7 5.73 + 1.22 5.20E-01 1.00E00 negative regulation of epithelial cell proliferation (GO:0050680) 116 14 11.47 + 1.22 4.42E-01 1.00E00 positive regulation of fibroblast proliferation (GO:0048146) 58 7 5.73 + 1.22 5.20E-01 1.00E00 positive regulation of dendritic spine development (GO:0060999) 58 7 5.73 + 1.22 5.20E-01 1.00E00 regulation of epithelial to mesenchymal transition (GO:0010717) 83 10 8.21 + 1.22 5.83E-01 1.00E00 associative learning (GO:0008306) 83 10 8.21 + 1.22 5.83E-01 1.00E00 striated muscle tissue development (GO:0014706) 249 30 24.62 + 1.22 2.91E-01 1.00E00 regulation of neurogenesis (GO:0050767) 357 43 35.30 + 1.22 2.15E-01 1.00E00 cellular response to tumor necrosis factor (GO:0071356) 108 13 10.68 + 1.22 5.21E-01 1.00E00 regulation of glucose metabolic process (GO:0010906) 108 13 10.68 + 1.22 5.21E-01 1.00E00 blood vessel morphogenesis (GO:0048514) 374 45 36.98 + 1.22 2.25E-01 1.00E00 cellular response to starvation (GO:0009267) 133 16 13.15 + 1.22 4.70E-01 1.00E00 regulation of signaling (GO:0023051) 2699 324 266.85 + 1.21 3.24E-04 1.42E-02 pigmentation (GO:0043473) 75 9 7.42 + 1.21 5.64E-01 1.00E00 regulation of actin filament polymerization (GO:0030833) 150 18 14.83 + 1.21 4.16E-01 1.00E00 chromatin organization involved in regulation of transcription (GO:0034401) 75 9 7.42 + 1.21 5.64E-01 1.00E00 epithelial tube branching involved in lung morphogenesis (GO:0060441) 25 3 2.47 + 1.21 7.36E-01 1.00E00 I-kappaB kinase/NF-kappaB signaling (GO:0007249) 50 6 4.94 + 1.21 6.37E-01 1.00E00 protein ADP-ribosylation (GO:0006471) 25 3 2.47 + 1.21 7.36E-01 1.00E00 regulation of cholesterol transport (GO:0032374) 50 6 4.94 + 1.21 6.37E-01 1.00E00 regulation of sterol transport (GO:0032371) 50 6 4.94 + 1.21 6.37E-01 1.00E00 regulation of skeletal muscle tissue development (GO:0048641) 25 3 2.47 + 1.21 7.36E-01 1.00E00 platelet aggregation (GO:0070527) 25 3 2.47 + 1.21 7.36E-01 1.00E00 synaptic vesicle recycling (GO:0036465) 50 6 4.94 + 1.21 6.37E-01 1.00E00 ruffle organization (GO:0031529) 25 3 2.47 + 1.21 7.36E-01 1.00E00 vascular associated smooth muscle cell differentiation (GO:0035886) 25 3 2.47 + 1.21 7.36E-01 1.00E00 nucleobase metabolic process (GO:0009112) 25 3 2.47 + 1.21 7.36E-01 1.00E00 myelination (GO:0042552) 100 12 9.89 + 1.21 5.06E-01 1.00E00 cardiac muscle cell action potential (GO:0086001) 25 3 2.47 + 1.21 7.36E-01 1.00E00 ceramide biosynthetic process (GO:0046513) 50 6 4.94 + 1.21 6.37E-01 1.00E00 negative regulation of blood circulation (GO:1903523) 25 3 2.47 + 1.21 7.36E-01 1.00E00 cardiac muscle hypertrophy (GO:0003300) 25 3 2.47 + 1.21 7.36E-01 1.00E00 positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) 25 3 2.47 + 1.21 7.36E-01 1.00E00 diol metabolic process (GO:0034311) 25 3 2.47 + 1.21 7.36E-01 1.00E00 motor neuron axon guidance (GO:0008045) 25 3 2.47 + 1.21 7.36E-01 1.00E00 negative regulation of protein tyrosine kinase activity (GO:0061099) 25 3 2.47 + 1.21 7.36E-01 1.00E00 regulation of cell growth involved in cardiac muscle cell development (GO:0061050) 25 3 2.47 + 1.21 7.36E-01 1.00E00 positive regulation of isotype switching (GO:0045830) 25 3 2.47 + 1.21 7.36E-01 1.00E00 regulation of cell communication (GO:0010646) 2687 322 265.67 + 1.21 4.12E-04 1.73E-02 regulation of biological quality (GO:0065008) 3105 372 307.00 + 1.21 1.04E-04 5.38E-03 negative regulation of signal transduction (GO:0009968) 1062 127 105.00 + 1.21 3.99E-02 5.39E-01 regulation of neurotransmitter secretion (GO:0046928) 92 11 9.10 + 1.21 4.91E-01 1.00E00 cellular response to endogenous stimulus (GO:0071495) 728 87 71.98 + 1.21 8.98E-02 8.40E-01 regulation of molecular function (GO:0065009) 2135 255 211.09 + 1.21 2.52E-03 7.50E-02 response to amino acid (GO:0043200) 67 8 6.62 + 1.21 5.45E-01 1.00E00 autophagosome organization (GO:1905037) 67 8 6.62 + 1.21 5.45E-01 1.00E00 positive regulation of biological process (GO:0048518) 5017 598 496.04 + 1.21 1.28E-07 1.68E-05 regulation of transcription regulatory region DNA binding (GO:2000677) 42 5 4.15 + 1.20 6.10E-01 1.00E00 purine nucleoside triphosphate biosynthetic process (GO:0009145) 42 5 4.15 + 1.20 6.10E-01 1.00E00 negative regulation of endocytosis (GO:0045806) 42 5 4.15 + 1.20 6.10E-01 1.00E00 regulation of ion transmembrane transporter activity (GO:0032412) 210 25 20.76 + 1.20 3.58E-01 1.00E00 regulation of heart contraction (GO:0008016) 143 17 14.14 + 1.20 4.86E-01 1.00E00 ensheathment of neurons (GO:0007272) 101 12 9.99 + 1.20 5.09E-01 1.00E00 positive regulation of transporter activity (GO:0032411) 101 12 9.99 + 1.20 5.09E-01 1.00E00 axon ensheathment (GO:0008366) 101 12 9.99 + 1.20 5.09E-01 1.00E00 muscle tissue morphogenesis (GO:0060415) 59 7 5.83 + 1.20 6.64E-01 1.00E00 regulation of osteoblast differentiation (GO:0045667) 118 14 11.67 + 1.20 5.39E-01 1.00E00 cellular response to leukemia inhibitory factor (GO:1990830) 118 14 11.67 + 1.20 5.39E-01 1.00E00 lens development in camera-type eye (GO:0002088) 59 7 5.83 + 1.20 6.64E-01 1.00E00 regulation of peptide hormone secretion (GO:0090276) 177 21 17.50 + 1.20 4.52E-01 1.00E00 pyruvate metabolic process (GO:0006090) 59 7 5.83 + 1.20 6.64E-01 1.00E00 positive regulation of viral process (GO:0048524) 59 7 5.83 + 1.20 6.64E-01 1.00E00 ribonucleoside triphosphate metabolic process (GO:0009199) 59 7 5.83 + 1.20 6.64E-01 1.00E00 carbohydrate transport (GO:0008643) 59 7 5.83 + 1.20 6.64E-01 1.00E00 organophosphate catabolic process (GO:0046434) 118 14 11.67 + 1.20 5.39E-01 1.00E00 feeding behavior (GO:0007631) 59 7 5.83 + 1.20 6.64E-01 1.00E00 regulation of small GTPase mediated signal transduction (GO:0051056) 211 25 20.86 + 1.20 3.60E-01 1.00E00 transforming growth factor beta receptor signaling pathway (GO:0007179) 76 9 7.51 + 1.20 5.68E-01 1.00E00 regulation of transferase activity (GO:0051338) 777 92 76.82 + 1.20 9.96E-02 8.66E-01 cellular response to growth factor stimulus (GO:0071363) 338 40 33.42 + 1.20 2.75E-01 1.00E00 negative regulation of protein binding (GO:0032091) 93 11 9.20 + 1.20 6.04E-01 1.00E00 animal organ development (GO:0048513) 2421 286 239.37 + 1.19 2.25E-03 6.79E-02 regulation of epithelial cell proliferation (GO:0050678) 305 36 30.16 + 1.19 2.93E-01 1.00E00 glycerolipid biosynthetic process (GO:0045017) 161 19 15.92 + 1.19 4.32E-01 1.00E00 regulation of protein serine/threonine kinase activity (GO:0071900) 373 44 36.88 + 1.19 2.59E-01 1.00E00 renal system process involved in regulation of systemic arterial blood pressure (GO:0003071) 17 2 1.68 + 1.19 6.87E-01 1.00E00 axon guidance (GO:0007411) 170 20 16.81 + 1.19 4.44E-01 1.00E00 regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) 17 2 1.68 + 1.19 6.87E-01 1.00E00 AMP metabolic process (GO:0046033) 17 2 1.68 + 1.19 6.87E-01 1.00E00 mitochondrial calcium ion transmembrane transport (GO:0006851) 17 2 1.68 + 1.19 6.87E-01 1.00E00 positive regulation of B cell differentiation (GO:0045579) 17 2 1.68 + 1.19 6.87E-01 1.00E00 negative regulation of cation channel activity (GO:2001258) 34 4 3.36 + 1.19 7.73E-01 1.00E00 regulation of response to wounding (GO:1903034) 136 16 13.45 + 1.19 4.77E-01 1.00E00 regulation of autophagosome assembly (GO:2000785) 34 4 3.36 + 1.19 7.73E-01 1.00E00 positive regulation of stem cell differentiation (GO:2000738) 17 2 1.68 + 1.19 6.87E-01 1.00E00 negative regulation of mononuclear cell migration (GO:0071676) 17 2 1.68 + 1.19 6.87E-01 1.00E00 regulation of monocyte chemotactic protein-1 production (GO:0071637) 17 2 1.68 + 1.19 6.87E-01 1.00E00 formation of primary germ layer (GO:0001704) 68 8 6.72 + 1.19 5.51E-01 1.00E00 polyamine metabolic process (GO:0006595) 17 2 1.68 + 1.19 6.87E-01 1.00E00 receptor catabolic process (GO:0032801) 17 2 1.68 + 1.19 6.87E-01 1.00E00 regulation of sodium ion transmembrane transport (GO:1902305) 51 6 5.04 + 1.19 6.41E-01 1.00E00 dopaminergic neuron differentiation (GO:0071542) 17 2 1.68 + 1.19 6.87E-01 1.00E00 negative regulation of muscle tissue development (GO:1901862) 17 2 1.68 + 1.19 6.87E-01 1.00E00 response to leukemia inhibitory factor (GO:1990823) 119 14 11.77 + 1.19 5.41E-01 1.00E00 cellular response to fluid shear stress (GO:0071498) 17 2 1.68 + 1.19 6.87E-01 1.00E00 V(D)J recombination (GO:0033151) 17 2 1.68 + 1.19 6.87E-01 1.00E00 regulation of clathrin-dependent endocytosis (GO:2000369) 17 2 1.68 + 1.19 6.87E-01 1.00E00 positive regulation of nuclear division (GO:0051785) 51 6 5.04 + 1.19 6.41E-01 1.00E00 regulation of mitotic spindle assembly (GO:1901673) 17 2 1.68 + 1.19 6.87E-01 1.00E00 transcytosis (GO:0045056) 17 2 1.68 + 1.19 6.87E-01 1.00E00 synaptic membrane adhesion (GO:0099560) 17 2 1.68 + 1.19 6.87E-01 1.00E00 melanosome localization (GO:0032400) 17 2 1.68 + 1.19 6.87E-01 1.00E00 regulation of fatty acid beta-oxidation (GO:0031998) 17 2 1.68 + 1.19 6.87E-01 1.00E00 regulation of cellular response to growth factor stimulus (GO:0090287) 238 28 23.53 + 1.19 3.86E-01 1.00E00 positive regulation of cholesterol transport (GO:0032376) 34 4 3.36 + 1.19 7.73E-01 1.00E00 positive regulation of sterol transport (GO:0032373) 34 4 3.36 + 1.19 7.73E-01 1.00E00 regulation of collateral sprouting (GO:0048670) 17 2 1.68 + 1.19 6.87E-01 1.00E00 negative regulation of smooth muscle cell proliferation (GO:0048662) 51 6 5.04 + 1.19 6.41E-01 1.00E00 positive regulation of skeletal muscle tissue development (GO:0048643) 17 2 1.68 + 1.19 6.87E-01 1.00E00 negative regulation of muscle organ development (GO:0048635) 17 2 1.68 + 1.19 6.87E-01 1.00E00 negative regulation of behavior (GO:0048521) 17 2 1.68 + 1.19 6.87E-01 1.00E00 circadian behavior (GO:0048512) 17 2 1.68 + 1.19 6.87E-01 1.00E00 regulation of ERBB signaling pathway (GO:1901184) 68 8 6.72 + 1.19 5.51E-01 1.00E00 protein insertion into mitochondrial membrane (GO:0051204) 17 2 1.68 + 1.19 6.87E-01 1.00E00 response to muscle stretch (GO:0035994) 17 2 1.68 + 1.19 6.87E-01 1.00E00 regulation of calcium ion transmembrane transporter activity (GO:1901019) 68 8 6.72 + 1.19 5.51E-01 1.00E00 negative regulation of potassium ion transmembrane transporter activity (GO:1901017) 17 2 1.68 + 1.19 6.87E-01 1.00E00 T cell apoptotic process (GO:0070231) 17 2 1.68 + 1.19 6.87E-01 1.00E00 positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:0035774) 34 4 3.36 + 1.19 7.73E-01 1.00E00 mammary gland development (GO:0030879) 102 12 10.08 + 1.19 5.13E-01 1.00E00 long-chain fatty acid biosynthetic process (GO:0042759) 17 2 1.68 + 1.19 6.87E-01 1.00E00 ATP synthesis coupled proton transport (GO:0015986) 17 2 1.68 + 1.19 6.87E-01 1.00E00 energy coupled proton transport, down electrochemical gradient (GO:0015985) 17 2 1.68 + 1.19 6.87E-01 1.00E00 anion homeostasis (GO:0055081) 34 4 3.36 + 1.19 7.73E-01 1.00E00 deoxyribonucleoside monophosphate metabolic process (GO:0009162) 17 2 1.68 + 1.19 6.87E-01 1.00E00 indole-containing compound metabolic process (GO:0042430) 17 2 1.68 + 1.19 6.87E-01 1.00E00 neuron projection guidance (GO:0097485) 170 20 16.81 + 1.19 4.44E-01 1.00E00 regulation of phospholipid metabolic process (GO:1903725) 34 4 3.36 + 1.19 7.73E-01 1.00E00 decidualization (GO:0046697) 17 2 1.68 + 1.19 6.87E-01 1.00E00 cellular modified amino acid catabolic process (GO:0042219) 17 2 1.68 + 1.19 6.87E-01 1.00E00 regulation of ketone biosynthetic process (GO:0010566) 17 2 1.68 + 1.19 6.87E-01 1.00E00 retina vasculature development in camera-type eye (GO:0061298) 17 2 1.68 + 1.19 6.87E-01 1.00E00 positive regulation of calcium ion transport into cytosol (GO:0010524) 51 6 5.04 + 1.19 6.41E-01 1.00E00 negative regulation of autophagy (GO:0010507) 68 8 6.72 + 1.19 5.51E-01 1.00E00 regulation of insulin secretion involved in cellular response to glucose stimulus (GO:0061178) 68 8 6.72 + 1.19 5.51E-01 1.00E00 3'-UTR-mediated mRNA destabilization (GO:0061158) 17 2 1.68 + 1.19 6.87E-01 1.00E00 circadian rhythm (GO:0007623) 102 12 10.08 + 1.19 5.13E-01 1.00E00 plasma lipoprotein particle assembly (GO:0034377) 17 2 1.68 + 1.19 6.87E-01 1.00E00 embryo implantation (GO:0007566) 34 4 3.36 + 1.19 7.73E-01 1.00E00 negative regulation of pri-miRNA transcription by RNA polymerase II (GO:1902894) 17 2 1.68 + 1.19 6.87E-01 1.00E00 regulation of transporter activity (GO:0032409) 230 27 22.74 + 1.19 3.79E-01 1.00E00 regulation of ion transmembrane transport (GO:0034765) 375 44 37.08 + 1.19 2.62E-01 1.00E00 negative regulation of cell communication (GO:0010648) 1152 135 113.90 + 1.19 5.37E-02 6.40E-01 regulation of fibroblast proliferation (GO:0048145) 94 11 9.29 + 1.18 6.06E-01 1.00E00 response to organonitrogen compound (GO:0010243) 641 75 63.38 + 1.18 1.61E-01 1.00E00 muscle tissue development (GO:0060537) 265 31 26.20 + 1.18 3.56E-01 1.00E00 epithelial cell proliferation (GO:0050673) 77 9 7.61 + 1.18 5.72E-01 1.00E00 regulation of Notch signaling pathway (GO:0008593) 77 9 7.61 + 1.18 5.72E-01 1.00E00 organ growth (GO:0035265) 77 9 7.61 + 1.18 5.72E-01 1.00E00 negative regulation of signaling (GO:0023057) 1156 135 114.30 + 1.18 6.06E-02 6.86E-01 inorganic ion import across plasma membrane (GO:0099587) 60 7 5.93 + 1.18 6.66E-01 1.00E00 inorganic cation import across plasma membrane (GO:0098659) 60 7 5.93 + 1.18 6.66E-01 1.00E00 morphogenesis of a branching structure (GO:0001763) 163 19 16.12 + 1.18 5.13E-01 1.00E00 regulated exocytosis (GO:0045055) 103 12 10.18 + 1.18 5.16E-01 1.00E00 regulation of sodium ion transmembrane transporter activity (GO:2000649) 43 5 4.25 + 1.18 6.17E-01 1.00E00 positive regulation of organic acid transport (GO:0032892) 43 5 4.25 + 1.18 6.17E-01 1.00E00 movement in host environment (GO:0052126) 43 5 4.25 + 1.18 6.17E-01 1.00E00 negative regulation of intracellular protein transport (GO:0090317) 43 5 4.25 + 1.18 6.17E-01 1.00E00 protein homotetramerization (GO:0051289) 43 5 4.25 + 1.18 6.17E-01 1.00E00 positive regulation of epithelial cell proliferation (GO:0050679) 172 20 17.01 + 1.18 4.48E-01 1.00E00 ribonucleoside triphosphate biosynthetic process (GO:0009201) 43 5 4.25 + 1.18 6.17E-01 1.00E00 positive regulation of transmembrane transport (GO:0034764) 198 23 19.58 + 1.17 4.76E-01 1.00E00 biomineralization (GO:0110148) 69 8 6.82 + 1.17 6.87E-01 1.00E00 biomineral tissue development (GO:0031214) 69 8 6.82 + 1.17 6.87E-01 1.00E00 secretion by cell (GO:0032940) 302 35 29.86 + 1.17 3.86E-01 1.00E00 regulation of actin polymerization or depolymerization (GO:0008064) 164 19 16.21 + 1.17 5.15E-01 1.00E00 regulation of GTPase activity (GO:0043087) 285 33 28.18 + 1.17 3.73E-01 1.00E00 positive regulation of cellular process (GO:0048522) 4650 538 459.75 + 1.17 3.36E-05 2.10E-03 regulation of insulin secretion (GO:0050796) 147 17 14.53 + 1.17 4.94E-01 1.00E00 gland development (GO:0048732) 320 37 31.64 + 1.17 3.50E-01 1.00E00 response to hormone (GO:0009725) 450 52 44.49 + 1.17 2.68E-01 1.00E00 zinc ion transport (GO:0006829) 26 3 2.57 + 1.17 7.42E-01 1.00E00 negative regulation of leukocyte mediated cytotoxicity (GO:0001911) 26 3 2.57 + 1.17 7.42E-01 1.00E00 biological phase (GO:0044848) 26 3 2.57 + 1.17 7.42E-01 1.00E00 behavioral fear response (GO:0001662) 26 3 2.57 + 1.17 7.42E-01 1.00E00 regulation of neurotransmitter transport (GO:0051588) 104 12 10.28 + 1.17 6.23E-01 1.00E00 mitochondrial calcium ion homeostasis (GO:0051560) 26 3 2.57 + 1.17 7.42E-01 1.00E00 positive regulation of release of cytochrome c from mitochondria (GO:0090200) 26 3 2.57 + 1.17 7.42E-01 1.00E00 positive regulation of dendrite morphogenesis (GO:0050775) 52 6 5.14 + 1.17 6.46E-01 1.00E00 positive regulation of protein modification process (GO:0031401) 884 102 87.40 + 1.17 1.35E-01 1.00E00 negative regulation of cardiac muscle tissue growth (GO:0055022) 26 3 2.57 + 1.17 7.42E-01 1.00E00 cardiac muscle tissue growth (GO:0055017) 26 3 2.57 + 1.17 7.42E-01 1.00E00 endocrine pancreas development (GO:0031018) 26 3 2.57 + 1.17 7.42E-01 1.00E00 glycerolipid metabolic process (GO:0046486) 286 33 28.28 + 1.17 3.74E-01 1.00E00 striated muscle hypertrophy (GO:0014897) 26 3 2.57 + 1.17 7.42E-01 1.00E00 negative regulation of heart growth (GO:0061117) 26 3 2.57 + 1.17 7.42E-01 1.00E00 positive regulation of natural killer cell mediated immunity (GO:0002717) 26 3 2.57 + 1.17 7.42E-01 1.00E00 clathrin-dependent endocytosis (GO:0072583) 26 3 2.57 + 1.17 7.42E-01 1.00E00 transmembrane transport (GO:0055085) 711 82 70.30 + 1.17 1.81E-01 1.00E00 striated muscle cell differentiation (GO:0051146) 165 19 16.31 + 1.16 5.16E-01 1.00E00 regulation of muscle contraction (GO:0006937) 122 14 12.06 + 1.16 5.48E-01 1.00E00 regulation of actin filament organization (GO:0110053) 244 28 24.12 + 1.16 4.54E-01 1.00E00 regulation of ATPase activity (GO:0043462) 61 7 6.03 + 1.16 6.70E-01 1.00E00 response to xenobiotic stimulus (GO:0009410) 61 7 6.03 + 1.16 6.70E-01 1.00E00 BMP signaling pathway (GO:0030509) 61 7 6.03 + 1.16 6.70E-01 1.00E00 chromatin organization involved in negative regulation of transcription (GO:0097549) 61 7 6.03 + 1.16 6.70E-01 1.00E00 secretion (GO:0046903) 375 43 37.08 + 1.16 3.41E-01 1.00E00 regulation of proteolysis (GO:0030162) 567 65 56.06 + 1.16 2.56E-01 1.00E00 intracellular signal transduction (GO:0035556) 1196 137 118.25 + 1.16 8.95E-02 8.42E-01 regulation of actin filament length (GO:0030832) 166 19 16.41 + 1.16 5.18E-01 1.00E00 cytosolic calcium ion transport (GO:0060401) 70 8 6.92 + 1.16 6.90E-01 1.00E00 positive regulation of apoptotic signaling pathway (GO:2001235) 140 16 13.84 + 1.16 5.73E-01 1.00E00 female meiotic nuclear division (GO:0007143) 35 4 3.46 + 1.16 7.76E-01 1.00E00 secretory granule organization (GO:0033363) 35 4 3.46 + 1.16 7.76E-01 1.00E00 intermediate filament cytoskeleton organization (GO:0045104) 35 4 3.46 + 1.16 7.76E-01 1.00E00 release of sequestered calcium ion into cytosol (GO:0051209) 35 4 3.46 + 1.16 7.76E-01 1.00E00 ribonucleotide catabolic process (GO:0009261) 35 4 3.46 + 1.16 7.76E-01 1.00E00 positive regulation of cardiac muscle tissue growth (GO:0055023) 35 4 3.46 + 1.16 7.76E-01 1.00E00 regulation of TORC1 signaling (GO:1903432) 35 4 3.46 + 1.16 7.76E-01 1.00E00 positive regulation of hydrolase activity (GO:0051345) 438 50 43.31 + 1.15 3.35E-01 1.00E00 extracellular matrix organization (GO:0030198) 219 25 21.65 + 1.15 4.98E-01 1.00E00 circulatory system development (GO:0072359) 772 88 76.33 + 1.15 1.98E-01 1.00E00 response to growth factor (GO:0070848) 351 40 34.70 + 1.15 3.71E-01 1.00E00 regulation of binding (GO:0051098) 351 40 34.70 + 1.15 3.71E-01 1.00E00 response to nitrogen compound (GO:1901698) 711 81 70.30 + 1.15 2.26E-01 1.00E00 peptidyl-threonine modification (GO:0018210) 79 9 7.81 + 1.15 7.07E-01 1.00E00 mitochondrial transmembrane transport (GO:1990542) 79 9 7.81 + 1.15 7.07E-01 1.00E00 regulation of oxidoreductase activity (GO:0051341) 79 9 7.81 + 1.15 7.07E-01 1.00E00 positive regulation of synaptic transmission (GO:0050806) 123 14 12.16 + 1.15 5.51E-01 1.00E00 cellular response to hormone stimulus (GO:0032870) 299 34 29.56 + 1.15 4.38E-01 1.00E00 branching morphogenesis of an epithelial tube (GO:0048754) 132 15 13.05 + 1.15 5.63E-01 1.00E00 regulation of leukocyte mediated cytotoxicity (GO:0001910) 88 10 8.70 + 1.15 5.98E-01 1.00E00 response to amino acid starvation (GO:1990928) 44 5 4.35 + 1.15 8.00E-01 1.00E00 external encapsulating structure organization (GO:0045229) 220 25 21.75 + 1.15 4.99E-01 1.00E00 digestive tract development (GO:0048565) 88 10 8.70 + 1.15 5.98E-01 1.00E00 regulation of T cell receptor signaling pathway (GO:0050856) 44 5 4.35 + 1.15 8.00E-01 1.00E00 negative regulation of DNA binding (GO:0043392) 44 5 4.35 + 1.15 8.00E-01 1.00E00 extracellular structure organization (GO:0043062) 220 25 21.75 + 1.15 4.99E-01 1.00E00 positive regulation of glucose transmembrane transport (GO:0010828) 44 5 4.35 + 1.15 8.00E-01 1.00E00 synapse organization (GO:0050808) 238 27 23.53 + 1.15 5.15E-01 1.00E00 cellular response to peptide hormone stimulus (GO:0071375) 159 18 15.72 + 1.14 5.96E-01 1.00E00 cell differentiation (GO:0030154) 2742 310 271.11 + 1.14 1.40E-02 2.68E-01 skeletal muscle organ development (GO:0060538) 115 13 11.37 + 1.14 6.40E-01 1.00E00 T cell differentiation in thymus (GO:0033077) 62 7 6.13 + 1.14 6.73E-01 1.00E00 regulation of cardiac muscle tissue growth (GO:0055021) 62 7 6.13 + 1.14 6.73E-01 1.00E00 regulation of cardiac muscle hypertrophy (GO:0010611) 62 7 6.13 + 1.14 6.73E-01 1.00E00 transport (GO:0006810) 2871 324 283.86 + 1.14 1.30E-02 2.57E-01 positive regulation of GTPase activity (GO:0043547) 204 23 20.17 + 1.14 5.58E-01 1.00E00 carbohydrate catabolic process (GO:0016052) 71 8 7.02 + 1.14 6.92E-01 1.00E00 bone morphogenesis (GO:0060349) 80 9 7.91 + 1.14 7.09E-01 1.00E00 positive regulation of endothelial cell proliferation (GO:0001938) 80 9 7.91 + 1.14 7.09E-01 1.00E00 regulation of neural precursor cell proliferation (GO:2000177) 80 9 7.91 + 1.14 7.09E-01 1.00E00 peptidyl-tyrosine phosphorylation (GO:0018108) 80 9 7.91 + 1.14 7.09E-01 1.00E00 apoptotic process (GO:0006915) 731 82 72.27 + 1.13 2.58E-01 1.00E00 negative regulation of cellular component organization (GO:0051129) 660 74 65.26 + 1.13 2.91E-01 1.00E00 negative regulation of cellular protein metabolic process (GO:0032269) 813 91 80.38 + 1.13 2.56E-01 1.00E00 response to organic cyclic compound (GO:0014070) 483 54 47.75 + 1.13 3.98E-01 1.00E00 negative regulation of biological process (GO:0048519) 4322 482 427.32 + 1.13 3.23E-03 9.06E-02 cellular developmental process (GO:0048869) 2789 311 275.75 + 1.13 2.79E-02 4.36E-01 protein localization to Golgi apparatus (GO:0034067) 27 3 2.67 + 1.12 7.49E-01 1.00E00 positive regulation of extrinsic apoptotic signaling pathway (GO:2001238) 54 6 5.34 + 1.12 8.19E-01 1.00E00 negative regulation of response to wounding (GO:1903035) 63 7 6.23 + 1.12 6.77E-01 1.00E00 regulation of vasoconstriction (GO:0019229) 63 7 6.23 + 1.12 6.77E-01 1.00E00 behavioral defense response (GO:0002209) 27 3 2.67 + 1.12 7.49E-01 1.00E00 positive regulation of cell division (GO:0051781) 63 7 6.23 + 1.12 6.77E-01 1.00E00 cell-cell fusion (GO:0140253) 27 3 2.67 + 1.12 7.49E-01 1.00E00 positive regulation of protein targeting to membrane (GO:0090314) 27 3 2.67 + 1.12 7.49E-01 1.00E00 vesicle cytoskeletal trafficking (GO:0099518) 63 7 6.23 + 1.12 6.77E-01 1.00E00 negative regulation of transporter activity (GO:0032410) 63 7 6.23 + 1.12 6.77E-01 1.00E00 negative regulation of lipid transport (GO:0032369) 27 3 2.67 + 1.12 7.49E-01 1.00E00 syncytium formation by plasma membrane fusion (GO:0000768) 27 3 2.67 + 1.12 7.49E-01 1.00E00 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway (GO:0051482) 27 3 2.67 + 1.12 7.49E-01 1.00E00 cellular lipid metabolic process (GO:0044255) 684 76 67.63 + 1.12 3.30E-01 1.00E00 carbohydrate derivative transport (GO:1901264) 54 6 5.34 + 1.12 8.19E-01 1.00E00 embryonic axis specification (GO:0000578) 27 3 2.67 + 1.12 7.49E-01 1.00E00 regulation of behavior (GO:0050795) 63 7 6.23 + 1.12 6.77E-01 1.00E00 sodium ion transmembrane transport (GO:0035725) 63 7 6.23 + 1.12 6.77E-01 1.00E00 regulation of neuronal synaptic plasticity (GO:0048168) 54 6 5.34 + 1.12 8.19E-01 1.00E00 nucleotide catabolic process (GO:0009166) 54 6 5.34 + 1.12 8.19E-01 1.00E00 positive regulation of G2/M transition of mitotic cell cycle (GO:0010971) 27 3 2.67 + 1.12 7.49E-01 1.00E00 hormone secretion (GO:0046879) 63 7 6.23 + 1.12 6.77E-01 1.00E00 positive regulation of smooth muscle contraction (GO:0045987) 27 3 2.67 + 1.12 7.49E-01 1.00E00 regulation of synaptic vesicle recycling (GO:1903421) 27 3 2.67 + 1.12 7.49E-01 1.00E00 protein localization to plasma membrane (GO:0072659) 189 21 18.69 + 1.12 6.26E-01 1.00E00 cardiac ventricle development (GO:0003231) 108 12 10.68 + 1.12 6.32E-01 1.00E00 regulation of supramolecular fiber organization (GO:1902903) 342 38 33.81 + 1.12 4.68E-01 1.00E00 regulation of muscle hypertrophy (GO:0014743) 63 7 6.23 + 1.12 6.77E-01 1.00E00 extracellular matrix assembly (GO:0085029) 27 3 2.67 + 1.12 7.49E-01 1.00E00 positive regulation of heart contraction (GO:0045823) 27 3 2.67 + 1.12 7.49E-01 1.00E00 forebrain neuron development (GO:0021884) 27 3 2.67 + 1.12 7.49E-01 1.00E00 response to lead ion (GO:0010288) 9 1 .89 + 1.12 6.11E-01 1.00E00 regulation of tolerance induction (GO:0002643) 18 2 1.78 + 1.12 7.00E-01 1.00E00 regulation of adenylate cyclase activity (GO:0045761) 18 2 1.78 + 1.12 7.00E-01 1.00E00 positive regulation of action potential (GO:0045760) 9 1 .89 + 1.12 6.11E-01 1.00E00 cerebral cortex cell migration (GO:0021795) 45 5 4.45 + 1.12 8.02E-01 1.00E00 positive regulation of tumor necrosis factor-mediated signaling pathway (GO:1903265) 9 1 .89 + 1.12 6.11E-01 1.00E00 foregut morphogenesis (GO:0007440) 9 1 .89 + 1.12 6.11E-01 1.00E00 regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) 18 2 1.78 + 1.12 7.00E-01 1.00E00 axonal fasciculation (GO:0007413) 18 2 1.78 + 1.12 7.00E-01 1.00E00 regulation of lens fiber cell differentiation (GO:1902746) 9 1 .89 + 1.12 6.11E-01 1.00E00 negative regulation of osteoblast differentiation (GO:0045668) 45 5 4.45 + 1.12 8.02E-01 1.00E00 negative regulation of osteoblast proliferation (GO:0033689) 9 1 .89 + 1.12 6.11E-01 1.00E00 positive regulation of endothelial cell differentiation (GO:0045603) 9 1 .89 + 1.12 6.11E-01 1.00E00 fusion of sperm to egg plasma membrane involved in single fertilization (GO:0007342) 9 1 .89 + 1.12 6.11E-01 1.00E00 insemination (GO:0007320) 9 1 .89 + 1.12 6.11E-01 1.00E00 cellular response to catecholamine stimulus (GO:0071870) 45 5 4.45 + 1.12 8.02E-01 1.00E00 response to catecholamine (GO:0071869) 45 5 4.45 + 1.12 8.02E-01 1.00E00 cellular response to monoamine stimulus (GO:0071868) 45 5 4.45 + 1.12 8.02E-01 1.00E00 response to monoamine (GO:0071867) 45 5 4.45 + 1.12 8.02E-01 1.00E00 tangential migration from the subventricular zone to the olfactory bulb (GO:0022028) 9 1 .89 + 1.12 6.11E-01 1.00E00 positive regulation of gamma-delta T cell differentiation (GO:0045588) 9 1 .89 + 1.12 6.11E-01 1.00E00 response to manganese ion (GO:0010042) 9 1 .89 + 1.12 6.11E-01 1.00E00 positive regulation of cholesterol biosynthetic process (GO:0045542) 9 1 .89 + 1.12 6.11E-01 1.00E00 cardioblast differentiation (GO:0010002) 9 1 .89 + 1.12 6.11E-01 1.00E00 pons development (GO:0021548) 9 1 .89 + 1.12 6.11E-01 1.00E00 synaptic transmission, dopaminergic (GO:0001963) 9 1 .89 + 1.12 6.11E-01 1.00E00 regulation of steroid metabolic process (GO:0019218) 90 10 8.90 + 1.12 7.24E-01 1.00E00 long-term synaptic depression (GO:0060292) 18 2 1.78 + 1.12 7.00E-01 1.00E00 positive regulation of cellular senescence (GO:2000774) 9 1 .89 + 1.12 6.11E-01 1.00E00 cellular detoxification of aldehyde (GO:0110095) 9 1 .89 + 1.12 6.11E-01 1.00E00 regulation of cardiac muscle cell differentiation (GO:2000725) 18 2 1.78 + 1.12 7.00E-01 1.00E00 marginal zone B cell differentiation (GO:0002315) 9 1 .89 + 1.12 6.11E-01 1.00E00 collagen biosynthetic process (GO:0032964) 9 1 .89 + 1.12 6.11E-01 1.00E00 sphingomyelin biosynthetic process (GO:0006686) 9 1 .89 + 1.12 6.11E-01 1.00E00 negative regulation of activin receptor signaling pathway (GO:0032926) 9 1 .89 + 1.12 6.11E-01 1.00E00 activin receptor signaling pathway (GO:0032924) 18 2 1.78 + 1.12 7.00E-01 1.00E00 regulation of transforming growth factor beta1 production (GO:0032908) 9 1 .89 + 1.12 6.11E-01 1.00E00 TORC1 signaling (GO:0038202) 9 1 .89 + 1.12 6.11E-01 1.00E00 mast cell activation involved in immune response (GO:0002279) 18 2 1.78 + 1.12 7.00E-01 1.00E00 negative regulation of cell cycle checkpoint (GO:1901977) 9 1 .89 + 1.12 6.11E-01 1.00E00 mitotic DNA replication checkpoint signaling (GO:0033314) 9 1 .89 + 1.12 6.11E-01 1.00E00 negative regulation of CD4-positive, alpha-beta T cell proliferation (GO:2000562) 9 1 .89 + 1.12 6.11E-01 1.00E00 positive regulation of T-helper 2 cell cytokine production (GO:2000553) 9 1 .89 + 1.12 6.11E-01 1.00E00 cellular response to insulin stimulus (GO:0032869) 117 13 11.57 + 1.12 6.44E-01 1.00E00 hard palate development (GO:0060022) 9 1 .89 + 1.12 6.11E-01 1.00E00 righting reflex (GO:0060013) 9 1 .89 + 1.12 6.11E-01 1.00E00 L-glutamate import (GO:0051938) 9 1 .89 + 1.12 6.11E-01 1.00E00 store-operated calcium entry (GO:0002115) 9 1 .89 + 1.12 6.11E-01 1.00E00 meiotic cytokinesis (GO:0033206) 9 1 .89 + 1.12 6.11E-01 1.00E00 osteoblast differentiation (GO:0001649) 72 8 7.12 + 1.12 6.95E-01 1.00E00 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage (GO:1902231) 9 1 .89 + 1.12 6.11E-01 1.00E00 'de novo' protein folding (GO:0006458) 36 4 3.56 + 1.12 7.80E-01 1.00E00 regulation of translational fidelity (GO:0006450) 9 1 .89 + 1.12 6.11E-01 1.00E00 cellular response to salt stress (GO:0071472) 9 1 .89 + 1.12 6.11E-01 1.00E00 pigment granule localization (GO:0051875) 18 2 1.78 + 1.12 7.00E-01 1.00E00 regulation of circadian sleep/wake cycle, non-REM sleep (GO:0045188) 9 1 .89 + 1.12 6.11E-01 1.00E00 desensitization of G protein-coupled receptor signaling pathway (GO:0002029) 18 2 1.78 + 1.12 7.00E-01 1.00E00 NADPH oxidation (GO:0070995) 9 1 .89 + 1.12 6.11E-01 1.00E00 azole transmembrane transport (GO:0045117) 9 1 .89 + 1.12 6.11E-01 1.00E00 intermediate filament-based process (GO:0045103) 36 4 3.56 + 1.12 7.80E-01 1.00E00 regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) 9 1 .89 + 1.12 6.11E-01 1.00E00 antiviral innate immune response (GO:0140374) 9 1 .89 + 1.12 6.11E-01 1.00E00 luteinization (GO:0001553) 9 1 .89 + 1.12 6.11E-01 1.00E00 biological process involved in intraspecies interaction between organisms (GO:0051703) 45 5 4.45 + 1.12 8.02E-01 1.00E00 positive regulation of myoblast proliferation (GO:2000288) 9 1 .89 + 1.12 6.11E-01 1.00E00 peripheral nervous system neuron development (GO:0048935) 9 1 .89 + 1.12 6.11E-01 1.00E00 peripheral nervous system neuron differentiation (GO:0048934) 9 1 .89 + 1.12 6.11E-01 1.00E00 negative regulation of fibroblast apoptotic process (GO:2000270) 9 1 .89 + 1.12 6.11E-01 1.00E00 axo-dendritic protein transport (GO:0099640) 9 1 .89 + 1.12 6.11E-01 1.00E00 somite rostral/caudal axis specification (GO:0032525) 9 1 .89 + 1.12 6.11E-01 1.00E00 response to muramyl dipeptide (GO:0032495) 18 2 1.78 + 1.12 7.00E-01 1.00E00 regulation of peptidyl-cysteine S-nitrosylation (GO:2000169) 9 1 .89 + 1.12 6.11E-01 1.00E00 negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) 9 1 .89 + 1.12 6.11E-01 1.00E00 locomotion involved in locomotory behavior (GO:0031987) 9 1 .89 + 1.12 6.11E-01 1.00E00 regulation of muscle system process (GO:0090257) 198 22 19.58 + 1.12 5.54E-01 1.00E00 regulation of spindle checkpoint (GO:0090231) 18 2 1.78 + 1.12 7.00E-01 1.00E00 lipid droplet formation (GO:0140042) 9 1 .89 + 1.12 6.11E-01 1.00E00 negative regulation of cholesterol transport (GO:0032375) 9 1 .89 + 1.12 6.11E-01 1.00E00 negative regulation of sterol transport (GO:0032372) 9 1 .89 + 1.12 6.11E-01 1.00E00 positive regulation of sterol biosynthetic process (GO:0106120) 9 1 .89 + 1.12 6.11E-01 1.00E00 positive regulation of chondrocyte differentiation (GO:0032332) 18 2 1.78 + 1.12 7.00E-01 1.00E00 N-acetylneuraminate metabolic process (GO:0006054) 9 1 .89 + 1.12 6.11E-01 1.00E00 positive regulation of phospholipid biosynthetic process (GO:0071073) 9 1 .89 + 1.12 6.11E-01 1.00E00 neuron apoptotic process (GO:0051402) 45 5 4.45 + 1.12 8.02E-01 1.00E00 regulation of cardiac muscle cell action potential (GO:0098901) 18 2 1.78 + 1.12 7.00E-01 1.00E00 dendrite self-avoidance (GO:0070593) 9 1 .89 + 1.12 6.11E-01 1.00E00 positive regulation of collateral sprouting (GO:0048672) 9 1 .89 + 1.12 6.11E-01 1.00E00 regulation of muscle organ development (GO:0048634) 45 5 4.45 + 1.12 8.02E-01 1.00E00 peripheral nervous system myelin maintenance (GO:0032287) 9 1 .89 + 1.12 6.11E-01 1.00E00 neuron projection fasciculation (GO:0106030) 18 2 1.78 + 1.12 7.00E-01 1.00E00 neuron projection organization (GO:0106027) 45 5 4.45 + 1.12 8.02E-01 1.00E00 cellular response to leucine starvation (GO:1990253) 9 1 .89 + 1.12 6.11E-01 1.00E00 positive regulation of extracellular matrix assembly (GO:1901203) 9 1 .89 + 1.12 6.11E-01 1.00E00 positive regulation of T cell receptor signaling pathway (GO:0050862) 18 2 1.78 + 1.12 7.00E-01 1.00E00 histone H3-K14 acetylation (GO:0044154) 9 1 .89 + 1.12 6.11E-01 1.00E00 establishment of spindle localization (GO:0051293) 45 5 4.45 + 1.12 8.02E-01 1.00E00 negative regulation of sequestering of calcium ion (GO:0051283) 36 4 3.56 + 1.12 7.80E-01 1.00E00 negative regulation of nervous system process (GO:0031645) 18 2 1.78 + 1.12 7.00E-01 1.00E00 positive regulation of fever generation (GO:0031622) 9 1 .89 + 1.12 6.11E-01 1.00E00 hepatocyte differentiation (GO:0070365) 9 1 .89 + 1.12 6.11E-01 1.00E00 negative regulation of dendrite morphogenesis (GO:0050774) 9 1 .89 + 1.12 6.11E-01 1.00E00 positive regulation of striated muscle cell differentiation (GO:0051155) 45 5 4.45 + 1.12 8.02E-01 1.00E00 negative regulation of thymocyte apoptotic process (GO:0070244) 9 1 .89 + 1.12 6.11E-01 1.00E00 paraxial mesoderm morphogenesis (GO:0048340) 9 1 .89 + 1.12 6.11E-01 1.00E00 postsynaptic specialization organization (GO:0099084) 18 2 1.78 + 1.12 7.00E-01 1.00E00 'de novo' posttranslational protein folding (GO:0051084) 36 4 3.56 + 1.12 7.80E-01 1.00E00 megakaryocyte development (GO:0035855) 18 2 1.78 + 1.12 7.00E-01 1.00E00 negative regulation of nitric-oxide synthase activity (GO:0051001) 9 1 .89 + 1.12 6.11E-01 1.00E00 enamel mineralization (GO:0070166) 9 1 .89 + 1.12 6.11E-01 1.00E00 behavioral response to pain (GO:0048266) 18 2 1.78 + 1.12 7.00E-01 1.00E00 response to UV-A (GO:0070141) 9 1 .89 + 1.12 6.11E-01 1.00E00 establishment or maintenance of cytoskeleton polarity (GO:0030952) 9 1 .89 + 1.12 6.11E-01 1.00E00 regulation of modification of synaptic structure (GO:1905244) 18 2 1.78 + 1.12 7.00E-01 1.00E00 mast cell degranulation (GO:0043303) 18 2 1.78 + 1.12 7.00E-01 1.00E00 folic acid-containing compound biosynthetic process (GO:0009396) 9 1 .89 + 1.12 6.11E-01 1.00E00 G1/S transition of mitotic cell cycle (GO:0000082) 72 8 7.12 + 1.12 6.95E-01 1.00E00 negative regulation of vascular permeability (GO:0043116) 18 2 1.78 + 1.12 7.00E-01 1.00E00 purine-containing compound salvage (GO:0043101) 9 1 .89 + 1.12 6.11E-01 1.00E00 regulation of hyaluronan biosynthetic process (GO:1900125) 9 1 .89 + 1.12 6.11E-01 1.00E00 positive regulation of execution phase of apoptosis (GO:1900119) 9 1 .89 + 1.12 6.11E-01 1.00E00 extracellular negative regulation of signal transduction (GO:1900116) 9 1 .89 + 1.12 6.11E-01 1.00E00 extracellular regulation of signal transduction (GO:1900115) 9 1 .89 + 1.12 6.11E-01 1.00E00 positive regulation of endoplasmic reticulum unfolded protein response (GO:1900103) 9 1 .89 + 1.12 6.11E-01 1.00E00 ATP transport (GO:0015867) 9 1 .89 + 1.12 6.11E-01 1.00E00 ventricular cardiac muscle cell development (GO:0055015) 9 1 .89 + 1.12 6.11E-01 1.00E00 post-embryonic camera-type eye development (GO:0031077) 9 1 .89 + 1.12 6.11E-01 1.00E00 chromatin remodeling at centromere (GO:0031055) 9 1 .89 + 1.12 6.11E-01 1.00E00 purine deoxyribonucleotide metabolic process (GO:0009151) 18 2 1.78 + 1.12 7.00E-01 1.00E00 basic amino acid transport (GO:0015802) 9 1 .89 + 1.12 6.11E-01 1.00E00 positive regulation of protein processing (GO:0010954) 18 2 1.78 + 1.12 7.00E-01 1.00E00 membrane depolarization during action potential (GO:0086010) 18 2 1.78 + 1.12 7.00E-01 1.00E00 necroptotic signaling pathway (GO:0097527) 9 1 .89 + 1.12 6.11E-01 1.00E00 norepinephrine metabolic process (GO:0042415) 9 1 .89 + 1.12 6.11E-01 1.00E00 peristalsis (GO:0030432) 9 1 .89 + 1.12 6.11E-01 1.00E00 regulation of protein ADP-ribosylation (GO:0010835) 9 1 .89 + 1.12 6.11E-01 1.00E00 negative regulation of mitochondrion organization (GO:0010823) 45 5 4.45 + 1.12 8.02E-01 1.00E00 negative regulation of peptidyl-threonine phosphorylation (GO:0010801) 18 2 1.78 + 1.12 7.00E-01 1.00E00 segmentation (GO:0035282) 72 8 7.12 + 1.12 6.95E-01 1.00E00 positive regulation of voltage-gated potassium channel activity (GO:1903818) 9 1 .89 + 1.12 6.11E-01 1.00E00 regulation of vesicle size (GO:0097494) 9 1 .89 + 1.12 6.11E-01 1.00E00 positive regulation of TORC1 signaling (GO:1904263) 18 2 1.78 + 1.12 7.00E-01 1.00E00 regulation of bile acid metabolic process (GO:1904251) 9 1 .89 + 1.12 6.11E-01 1.00E00 protein kinase A signaling (GO:0010737) 9 1 .89 + 1.12 6.11E-01 1.00E00 social behavior (GO:0035176) 45 5 4.45 + 1.12 8.02E-01 1.00E00 positive regulation of gamma-delta T cell activation (GO:0046645) 9 1 .89 + 1.12 6.11E-01 1.00E00 negative regulation of retrograde protein transport, ER to cytosol (GO:1904153) 9 1 .89 + 1.12 6.11E-01 1.00E00 regulation of complement-dependent cytotoxicity (GO:1903659) 9 1 .89 + 1.12 6.11E-01 1.00E00 sperm-egg recognition (GO:0035036) 36 4 3.56 + 1.12 7.80E-01 1.00E00 sphingoid metabolic process (GO:0046519) 18 2 1.78 + 1.12 7.00E-01 1.00E00 neurotransmitter catabolic process (GO:0042135) 9 1 .89 + 1.12 6.11E-01 1.00E00 regulation of blood pressure (GO:0008217) 144 16 14.24 + 1.12 6.76E-01 1.00E00 spermidine metabolic process (GO:0008216) 9 1 .89 + 1.12 6.11E-01 1.00E00 glucocorticoid metabolic process (GO:0008211) 9 1 .89 + 1.12 6.11E-01 1.00E00 urate metabolic process (GO:0046415) 9 1 .89 + 1.12 6.11E-01 1.00E00 positive regulation of striated muscle contraction (GO:0045989) 9 1 .89 + 1.12 6.11E-01 1.00E00 negative adaptation of signaling pathway (GO:0022401) 18 2 1.78 + 1.12 7.00E-01 1.00E00 lung secretory cell differentiation (GO:0061140) 9 1 .89 + 1.12 6.11E-01 1.00E00 telencephalon regionalization (GO:0021978) 9 1 .89 + 1.12 6.11E-01 1.00E00 rostrocaudal neural tube patterning (GO:0021903) 9 1 .89 + 1.12 6.11E-01 1.00E00 rhythmic behavior (GO:0007622) 18 2 1.78 + 1.12 7.00E-01 1.00E00 deoxyribose phosphate catabolic process (GO:0046386) 18 2 1.78 + 1.12 7.00E-01 1.00E00 cardiac chamber formation (GO:0003207) 9 1 .89 + 1.12 6.11E-01 1.00E00 regulation of alcohol biosynthetic process (GO:1902930) 45 5 4.45 + 1.12 8.02E-01 1.00E00 positive regulation of glucose import (GO:0046326) 36 4 3.56 + 1.12 7.80E-01 1.00E00 diol biosynthetic process (GO:0034312) 18 2 1.78 + 1.12 7.00E-01 1.00E00 energy homeostasis (GO:0097009) 36 4 3.56 + 1.12 7.80E-01 1.00E00 positive regulation of dendritic cell cytokine production (GO:0002732) 9 1 .89 + 1.12 6.11E-01 1.00E00 regulation of histone H3-K27 methylation (GO:0061085) 9 1 .89 + 1.12 6.11E-01 1.00E00 epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) 9 1 .89 + 1.12 6.11E-01 1.00E00 liver morphogenesis (GO:0072576) 9 1 .89 + 1.12 6.11E-01 1.00E00 regulation of nervous system development (GO:0051960) 433 48 42.81 + 1.12 4.19E-01 1.00E00 organic hydroxy compound metabolic process (GO:1901615) 325 36 32.13 + 1.12 5.14E-01 1.00E00 regulation of protein-containing complex assembly (GO:0043254) 398 44 39.35 + 1.12 4.49E-01 1.00E00 small molecule biosynthetic process (GO:0044283) 371 41 36.68 + 1.12 4.85E-01 1.00E00 regulation of cell junction assembly (GO:1901888) 181 20 17.90 + 1.12 6.19E-01 1.00E00 regulation of protein localization to membrane (GO:1905475) 181 20 17.90 + 1.12 6.19E-01 1.00E00 establishment of localization (GO:0051234) 3014 333 298.00 + 1.12 3.27E-02 4.75E-01 bone development (GO:0060348) 172 19 17.01 + 1.12 6.11E-01 1.00E00 cell death (GO:0008219) 797 88 78.80 + 1.12 3.05E-01 1.00E00 intrinsic apoptotic signaling pathway (GO:0097193) 145 16 14.34 + 1.12 6.77E-01 1.00E00 muscle cell development (GO:0055001) 136 15 13.45 + 1.12 6.67E-01 1.00E00 positive regulation of cysteine-type endopeptidase activity (GO:2001056) 127 14 12.56 + 1.11 6.57E-01 1.00E00 localization (GO:0051179) 4019 443 397.36 + 1.11 1.18E-02 2.46E-01 sodium ion transport (GO:0006814) 118 13 11.67 + 1.11 6.47E-01 1.00E00 regulation of epithelial cell differentiation (GO:0030856) 118 13 11.67 + 1.11 6.47E-01 1.00E00 positive regulation of protein metabolic process (GO:0051247) 1280 141 126.56 + 1.11 2.07E-01 1.00E00 programmed cell death (GO:0012501) 763 84 75.44 + 1.11 3.24E-01 1.00E00 regulation of receptor-mediated endocytosis (GO:0048259) 109 12 10.78 + 1.11 7.49E-01 1.00E00 positive regulation of cell cycle phase transition (GO:1901989) 100 11 9.89 + 1.11 7.38E-01 1.00E00 regulation of synapse assembly (GO:0051963) 91 10 9.00 + 1.11 7.26E-01 1.00E00 system development (GO:0048731) 3249 357 321.23 + 1.11 3.47E-02 4.95E-01 mesenchyme development (GO:0060485) 173 19 17.10 + 1.11 6.13E-01 1.00E00 regulation of pH (GO:0006885) 82 9 8.11 + 1.11 7.13E-01 1.00E00 positive regulation of leukocyte mediated cytotoxicity (GO:0001912) 64 7 6.33 + 1.11 6.82E-01 1.00E00 negative regulation of response to DNA damage stimulus (GO:2001021) 64 7 6.33 + 1.11 6.82E-01 1.00E00 neuromuscular process (GO:0050905) 128 14 12.66 + 1.11 6.59E-01 1.00E00 negative regulation of protein secretion (GO:0050709) 64 7 6.33 + 1.11 6.82E-01 1.00E00 cell junction organization (GO:0034330) 394 43 38.96 + 1.10 4.99E-01 1.00E00 positive regulation of synapse assembly (GO:0051965) 55 6 5.44 + 1.10 8.21E-01 1.00E00 cellular response to xenobiotic stimulus (GO:0071466) 55 6 5.44 + 1.10 8.21E-01 1.00E00 negative regulation of ion transmembrane transporter activity (GO:0032413) 55 6 5.44 + 1.10 8.21E-01 1.00E00 positive regulation of receptor-mediated endocytosis (GO:0048260) 55 6 5.44 + 1.10 8.21E-01 1.00E00 cardiac chamber morphogenesis (GO:0003206) 110 12 10.88 + 1.10 7.50E-01 1.00E00 skeletal muscle tissue development (GO:0007519) 110 12 10.88 + 1.10 7.50E-01 1.00E00 regulation of synapse organization (GO:0050807) 211 23 20.86 + 1.10 6.45E-01 1.00E00 regulation of intrinsic apoptotic signaling pathway (GO:2001242) 156 17 15.42 + 1.10 6.88E-01 1.00E00 negative regulation of cellular process (GO:0048523) 3974 433 392.91 + 1.10 2.64E-02 4.16E-01 negative regulation of binding (GO:0051100) 147 16 14.53 + 1.10 6.80E-01 1.00E00 carbohydrate metabolic process (GO:0005975) 340 37 33.62 + 1.10 5.84E-01 1.00E00 protein maturation (GO:0051604) 193 21 19.08 + 1.10 6.31E-01 1.00E00 lipid metabolic process (GO:0006629) 855 93 84.54 + 1.10 3.80E-01 1.00E00 heart development (GO:0007507) 469 51 46.37 + 1.10 4.84E-01 1.00E00 placenta development (GO:0001890) 138 15 13.64 + 1.10 6.71E-01 1.00E00 lung morphogenesis (GO:0060425) 46 5 4.55 + 1.10 8.05E-01 1.00E00 mesoderm formation (GO:0001707) 46 5 4.55 + 1.10 8.05E-01 1.00E00 regulation of postsynapse organization (GO:0099175) 92 10 9.10 + 1.10 7.28E-01 1.00E00 positive regulation of neuron projection development (GO:0010976) 184 20 18.19 + 1.10 6.24E-01 1.00E00 cation transmembrane transport (GO:0098655) 359 39 35.49 + 1.10 5.36E-01 1.00E00 calcium ion transport (GO:0006816) 175 19 17.30 + 1.10 7.04E-01 1.00E00 cellular carbohydrate metabolic process (GO:0044262) 129 14 12.75 + 1.10 6.62E-01 1.00E00 regulation of protein modification process (GO:0031399) 1346 146 133.08 + 1.10 2.75E-01 1.00E00 peptidyl-tyrosine modification (GO:0018212) 83 9 8.21 + 1.10 7.16E-01 1.00E00 positive regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032436) 83 9 8.21 + 1.10 7.16E-01 1.00E00 negative regulation of transferase activity (GO:0051348) 240 26 23.73 + 1.10 6.65E-01 1.00E00 positive regulation of cell-substrate adhesion (GO:0010811) 120 13 11.86 + 1.10 7.60E-01 1.00E00 positive regulation of heart growth (GO:0060421) 37 4 3.66 + 1.09 7.84E-01 1.00E00 cell cycle G1/S phase transition (GO:0044843) 74 8 7.32 + 1.09 7.02E-01 1.00E00 regulation of hormone metabolic process (GO:0032350) 37 4 3.66 + 1.09 7.84E-01 1.00E00 endocrine process (GO:0050886) 37 4 3.66 + 1.09 7.84E-01 1.00E00 musculoskeletal movement (GO:0050881) 37 4 3.66 + 1.09 7.84E-01 1.00E00 multicellular organismal movement (GO:0050879) 37 4 3.66 + 1.09 7.84E-01 1.00E00 cortical actin cytoskeleton organization (GO:0030866) 37 4 3.66 + 1.09 7.84E-01 1.00E00 negative regulation of phosphatase activity (GO:0010923) 37 4 3.66 + 1.09 7.84E-01 1.00E00 negative regulation of organ growth (GO:0046621) 37 4 3.66 + 1.09 7.84E-01 1.00E00 positive regulation of muscle contraction (GO:0045933) 37 4 3.66 + 1.09 7.84E-01 1.00E00 purine-containing compound catabolic process (GO:0072523) 37 4 3.66 + 1.09 7.84E-01 1.00E00 cellular response to transforming growth factor beta stimulus (GO:0071560) 111 12 10.97 + 1.09 7.51E-01 1.00E00 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043280) 111 12 10.97 + 1.09 7.51E-01 1.00E00 muscle cell differentiation (GO:0042692) 222 24 21.95 + 1.09 6.53E-01 1.00E00 regulation of cation channel activity (GO:2001257) 139 15 13.74 + 1.09 6.73E-01 1.00E00 anatomical structure homeostasis (GO:0060249) 278 30 27.49 + 1.09 6.15E-01 1.00E00 vacuole organization (GO:0007033) 139 15 13.74 + 1.09 6.73E-01 1.00E00 regulation of protein polymerization (GO:0032271) 204 22 20.17 + 1.09 6.41E-01 1.00E00 negative regulation of cellular amide metabolic process (GO:0034249) 167 18 16.51 + 1.09 6.98E-01 1.00E00 regulation of cell growth (GO:0001558) 362 39 35.79 + 1.09 5.96E-01 1.00E00 peptidyl-serine modification (GO:0018209) 195 21 19.28 + 1.09 7.19E-01 1.00E00 muscle organ morphogenesis (GO:0048644) 65 7 6.43 + 1.09 8.35E-01 1.00E00 purine nucleoside triphosphate metabolic process (GO:0009144) 65 7 6.43 + 1.09 8.35E-01 1.00E00 positive regulation of cell morphogenesis involved in differentiation (GO:0010770) 93 10 9.20 + 1.09 7.30E-01 1.00E00 positive regulation of metabolic process (GO:0009893) 3061 329 302.65 + 1.09 1.06E-01 8.95E-01 heart morphogenesis (GO:0003007) 214 23 21.16 + 1.09 6.48E-01 1.00E00 regulation of cell projection assembly (GO:0060491) 177 19 17.50 + 1.09 7.06E-01 1.00E00 negative regulation of cell projection organization (GO:0031345) 177 19 17.50 + 1.09 7.06E-01 1.00E00 positive regulation of mitotic cell cycle phase transition (GO:1901992) 84 9 8.31 + 1.08 7.19E-01 1.00E00 response to acid chemical (GO:0001101) 84 9 8.31 + 1.08 7.19E-01 1.00E00 protein processing (GO:0016485) 140 15 13.84 + 1.08 7.77E-01 1.00E00 regulation of type I interferon-mediated signaling pathway (GO:0060338) 28 3 2.77 + 1.08 7.55E-01 1.00E00 proton transmembrane transport (GO:1902600) 56 6 5.54 + 1.08 8.23E-01 1.00E00 endochondral ossification (GO:0001958) 28 3 2.77 + 1.08 7.55E-01 1.00E00 glutamate receptor signaling pathway (GO:0007215) 28 3 2.77 + 1.08 7.55E-01 1.00E00 positive regulation of gene silencing by miRNA (GO:2000637) 28 3 2.77 + 1.08 7.55E-01 1.00E00 replacement ossification (GO:0036075) 28 3 2.77 + 1.08 7.55E-01 1.00E00 regulation of histone deacetylation (GO:0031063) 28 3 2.77 + 1.08 7.55E-01 1.00E00 fear response (GO:0042596) 28 3 2.77 + 1.08 7.55E-01 1.00E00 regulation of hormone biosynthetic process (GO:0046885) 28 3 2.77 + 1.08 7.55E-01 1.00E00 regulation of tumor necrosis factor-mediated signaling pathway (GO:0010803) 28 3 2.77 + 1.08 7.55E-01 1.00E00 cellular hormone metabolic process (GO:0034754) 56 6 5.54 + 1.08 8.23E-01 1.00E00 vasoconstriction (GO:0042310) 28 3 2.77 + 1.08 7.55E-01 1.00E00 negative regulation of cardiac muscle cell apoptotic process (GO:0010667) 28 3 2.77 + 1.08 7.55E-01 1.00E00 membrane lipid catabolic process (GO:0046466) 28 3 2.77 + 1.08 7.55E-01 1.00E00 fatty acid metabolic process (GO:0006631) 243 26 24.03 + 1.08 6.67E-01 1.00E00 positive regulation of cellular protein metabolic process (GO:0032270) 1206 129 119.24 + 1.08 3.69E-01 1.00E00 negative regulation of MAPK cascade (GO:0043409) 159 17 15.72 + 1.08 6.92E-01 1.00E00 regulation of cytoskeleton organization (GO:0051493) 468 50 46.27 + 1.08 5.85E-01 1.00E00 negative regulation of protein metabolic process (GO:0051248) 871 93 86.12 + 1.08 4.51E-01 1.00E00 regulation of trans-synaptic signaling (GO:0099177) 403 43 39.85 + 1.08 6.15E-01 1.00E00 central nervous system development (GO:0007417) 675 72 66.74 + 1.08 5.13E-01 1.00E00 hair follicle development (GO:0001942) 75 8 7.42 + 1.08 8.46E-01 1.00E00 nephron epithelium development (GO:0072009) 75 8 7.42 + 1.08 8.46E-01 1.00E00 positive regulation of macromolecule metabolic process (GO:0010604) 2804 299 277.24 + 1.08 1.74E-01 9.74E-01 regulation of pathway-restricted SMAD protein phosphorylation (GO:0060393) 47 5 4.65 + 1.08 8.08E-01 1.00E00 retina homeostasis (GO:0001895) 47 5 4.65 + 1.08 8.08E-01 1.00E00 lysosomal transport (GO:0007041) 94 10 9.29 + 1.08 7.33E-01 1.00E00 negative regulation of protein kinase activity (GO:0006469) 188 20 18.59 + 1.08 7.15E-01 1.00E00 receptor clustering (GO:0043113) 47 5 4.65 + 1.08 8.08E-01 1.00E00 regulation of cardiac muscle cell apoptotic process (GO:0010665) 47 5 4.65 + 1.08 8.08E-01 1.00E00 cell junction assembly (GO:0034329) 188 20 18.59 + 1.08 7.15E-01 1.00E00 biological regulation (GO:0065007) 9095 967 899.24 + 1.08 5.16E-04 2.12E-02 negative regulation of kinase activity (GO:0033673) 207 22 20.47 + 1.07 7.27E-01 1.00E00 regulation of intracellular pH (GO:0051453) 66 7 6.53 + 1.07 8.37E-01 1.00E00 behavior (GO:0007610) 510 54 50.42 + 1.07 6.00E-01 1.00E00 nephron development (GO:0072006) 104 11 10.28 + 1.07 7.45E-01 1.00E00 negative regulation of developmental growth (GO:0048640) 104 11 10.28 + 1.07 7.45E-01 1.00E00 dephosphorylation (GO:0016311) 208 22 20.57 + 1.07 7.28E-01 1.00E00 adult behavior (GO:0030534) 123 13 12.16 + 1.07 7.64E-01 1.00E00 protein complex oligomerization (GO:0051259) 180 19 17.80 + 1.07 8.03E-01 1.00E00 regulation of biological process (GO:0050789) 8653 913 855.53 + 1.07 3.77E-03 1.03E-01 positive regulation of protein transport (GO:0051222) 275 29 27.19 + 1.07 6.87E-01 1.00E00 muscle structure development (GO:0061061) 389 41 38.46 + 1.07 6.69E-01 1.00E00 positive regulation of blood pressure (GO:0045777) 38 4 3.76 + 1.06 7.88E-01 1.00E00 purine ribonucleoside metabolic process (GO:0046128) 19 2 1.88 + 1.06 7.13E-01 1.00E00 trabecula formation (GO:0060343) 19 2 1.88 + 1.06 7.13E-01 1.00E00 mast cell mediated immunity (GO:0002448) 19 2 1.88 + 1.06 7.13E-01 1.00E00 positive regulation of neuron migration (GO:2001224) 19 2 1.88 + 1.06 7.13E-01 1.00E00 endothelial cell proliferation (GO:0001935) 19 2 1.88 + 1.06 7.13E-01 1.00E00 release of cytochrome c from mitochondria (GO:0001836) 19 2 1.88 + 1.06 7.13E-01 1.00E00 regulation of cardiac muscle cell proliferation (GO:0060043) 38 4 3.76 + 1.06 7.88E-01 1.00E00 response to angiotensin (GO:1990776) 19 2 1.88 + 1.06 7.13E-01 1.00E00 positive regulation of neuroblast proliferation (GO:0002052) 19 2 1.88 + 1.06 7.13E-01 1.00E00 cellular pigmentation (GO:0033059) 38 4 3.76 + 1.06 7.88E-01 1.00E00 regulation of establishment of cell polarity (GO:2000114) 19 2 1.88 + 1.06 7.13E-01 1.00E00 regulation of vascular endothelial cell proliferation (GO:1905562) 19 2 1.88 + 1.06 7.13E-01 1.00E00 positive regulation of vascular associated smooth muscle cell migration (GO:1904754) 19 2 1.88 + 1.06 7.13E-01 1.00E00 deoxyribonucleotide catabolic process (GO:0009264) 19 2 1.88 + 1.06 7.13E-01 1.00E00 regulation of hair cycle (GO:0042634) 19 2 1.88 + 1.06 7.13E-01 1.00E00 aromatic amino acid family metabolic process (GO:0009072) 19 2 1.88 + 1.06 7.13E-01 1.00E00 embryonic hindlimb morphogenesis (GO:0035116) 19 2 1.88 + 1.06 7.13E-01 1.00E00 negative regulation of gene silencing by miRNA (GO:0060965) 19 2 1.88 + 1.06 7.13E-01 1.00E00 positive regulation of cardiac muscle cell apoptotic process (GO:0010666) 19 2 1.88 + 1.06 7.13E-01 1.00E00 response to nicotine (GO:0035094) 19 2 1.88 + 1.06 7.13E-01 1.00E00 adaptation of signaling pathway (GO:0023058) 19 2 1.88 + 1.06 7.13E-01 1.00E00 proteoglycan biosynthetic process (GO:0030166) 38 4 3.76 + 1.06 7.88E-01 1.00E00 acylglycerol catabolic process (GO:0046464) 19 2 1.88 + 1.06 7.13E-01 1.00E00 neutral lipid catabolic process (GO:0046461) 19 2 1.88 + 1.06 7.13E-01 1.00E00 myoblast fusion (GO:0007520) 19 2 1.88 + 1.06 7.13E-01 1.00E00 pyridine-containing compound biosynthetic process (GO:0072525) 19 2 1.88 + 1.06 7.13E-01 1.00E00 metanephros development (GO:0001656) 57 6 5.64 + 1.06 8.25E-01 1.00E00 learning (GO:0007612) 133 14 13.15 + 1.06 7.72E-01 1.00E00 regulation of autophagy (GO:0010506) 238 25 23.53 + 1.06 7.44E-01 1.00E00 enzyme linked receptor protein signaling pathway (GO:0007167) 457 48 45.18 + 1.06 6.93E-01 1.00E00 reproductive structure development (GO:0048608) 343 36 33.91 + 1.06 7.16E-01 1.00E00 cytoskeleton organization (GO:0007010) 963 101 95.21 + 1.06 5.42E-01 1.00E00 axonogenesis (GO:0007409) 267 28 26.40 + 1.06 7.58E-01 1.00E00 organic hydroxy compound biosynthetic process (GO:1901617) 124 13 12.26 + 1.06 7.65E-01 1.00E00 system process (GO:0003008) 1174 123 116.08 + 1.06 5.11E-01 1.00E00 positive regulation of peptidase activity (GO:0010952) 153 16 15.13 + 1.06 7.87E-01 1.00E00 regulation of synapse structure or activity (GO:0050803) 220 23 21.75 + 1.06 7.36E-01 1.00E00 lipid biosynthetic process (GO:0008610) 421 44 41.62 + 1.06 6.82E-01 1.00E00 regulation of heart growth (GO:0060420) 67 7 6.62 + 1.06 8.38E-01 1.00E00 negative regulation of neuron differentiation (GO:0045665) 67 7 6.62 + 1.06 8.38E-01 1.00E00 cellular response to BMP stimulus (GO:0071773) 67 7 6.62 + 1.06 8.38E-01 1.00E00 response to BMP (GO:0071772) 67 7 6.62 + 1.06 8.38E-01 1.00E00 modulation of chemical synaptic transmission (GO:0050804) 402 42 39.75 + 1.06 7.36E-01 1.00E00 embryonic heart tube development (GO:0035050) 67 7 6.62 + 1.06 8.38E-01 1.00E00 glycoprotein metabolic process (GO:0009100) 249 26 24.62 + 1.06 7.50E-01 1.00E00 heart looping (GO:0001947) 48 5 4.75 + 1.05 8.11E-01 1.00E00 response to cAMP (GO:0051591) 48 5 4.75 + 1.05 8.11E-01 1.00E00 regulation of ubiquitin-protein transferase activity (GO:0051438) 48 5 4.75 + 1.05 8.11E-01 1.00E00 membrane biogenesis (GO:0044091) 48 5 4.75 + 1.05 8.11E-01 1.00E00 regulation of potassium ion transmembrane transporter activity (GO:1901016) 48 5 4.75 + 1.05 8.11E-01 1.00E00 calcium ion transmembrane import into cytosol (GO:0097553) 48 5 4.75 + 1.05 8.11E-01 1.00E00 regulation of organ growth (GO:0046620) 96 10 9.49 + 1.05 8.64E-01 1.00E00 reproductive system development (GO:0061458) 346 36 34.21 + 1.05 7.18E-01 1.00E00 skin epidermis development (GO:0098773) 77 8 7.61 + 1.05 8.49E-01 1.00E00 negative regulation of organelle organization (GO:0010639) 308 32 30.45 + 1.05 7.74E-01 1.00E00 kidney epithelium development (GO:0072073) 106 11 10.48 + 1.05 8.71E-01 1.00E00 membrane lipid biosynthetic process (GO:0046467) 106 11 10.48 + 1.05 8.71E-01 1.00E00 regulation of cellular protein metabolic process (GO:0032268) 1986 206 196.36 + 1.05 4.70E-01 1.00E00 tube morphogenesis (GO:0035239) 618 64 61.10 + 1.05 7.32E-01 1.00E00 ion transmembrane transport (GO:0034220) 454 47 44.89 + 1.05 7.51E-01 1.00E00 olfactory bulb development (GO:0021772) 29 3 2.87 + 1.05 7.63E-01 1.00E00 neuroblast proliferation (GO:0007405) 29 3 2.87 + 1.05 7.63E-01 1.00E00 heart growth (GO:0060419) 29 3 2.87 + 1.05 7.63E-01 1.00E00 syncytium formation (GO:0006949) 29 3 2.87 + 1.05 7.63E-01 1.00E00 positive regulation of posttranscriptional gene silencing (GO:0060148) 29 3 2.87 + 1.05 7.63E-01 1.00E00 positive regulation of defense response to virus by host (GO:0002230) 29 3 2.87 + 1.05 7.63E-01 1.00E00 nuclear migration (GO:0007097) 29 3 2.87 + 1.05 7.63E-01 1.00E00 response to transforming growth factor beta (GO:0071559) 116 12 11.47 + 1.05 8.76E-01 1.00E00 regulation of cellular amine metabolic process (GO:0033238) 29 3 2.87 + 1.05 7.63E-01 1.00E00 positive regulation of receptor internalization (GO:0002092) 29 3 2.87 + 1.05 7.63E-01 1.00E00 cellular response to osmotic stress (GO:0071470) 29 3 2.87 + 1.05 7.63E-01 1.00E00 positive regulation of protein deacetylation (GO:0090312) 29 3 2.87 + 1.05 7.63E-01 1.00E00 regulation of voltage-gated calcium channel activity (GO:1901385) 29 3 2.87 + 1.05 7.63E-01 1.00E00 regulation of synaptic transmission, GABAergic (GO:0032228) 29 3 2.87 + 1.05 7.63E-01 1.00E00 regulation of protein transport (GO:0051223) 464 48 45.88 + 1.05 7.53E-01 1.00E00 establishment of mitotic spindle orientation (GO:0000132) 29 3 2.87 + 1.05 7.63E-01 1.00E00 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:0042771) 29 3 2.87 + 1.05 7.63E-01 1.00E00 positive regulation of mitotic cell cycle (GO:0045931) 116 12 11.47 + 1.05 8.76E-01 1.00E00 positive regulation of axonogenesis (GO:0050772) 87 9 8.60 + 1.05 8.58E-01 1.00E00 regulation of plasma membrane bounded cell projection assembly (GO:0120032) 174 18 17.20 + 1.05 8.00E-01 1.00E00 regulation of cellular process (GO:0050794) 8276 856 818.26 + 1.05 6.04E-02 6.85E-01 negative regulation of protein modification process (GO:0031400) 474 49 46.87 + 1.05 7.56E-01 1.00E00 regulation of muscle cell differentiation (GO:0051147) 126 13 12.46 + 1.04 8.81E-01 1.00E00 fertilization (GO:0009566) 126 13 12.46 + 1.04 8.81E-01 1.00E00 regulation of animal organ morphogenesis (GO:2000027) 97 10 9.59 + 1.04 8.65E-01 1.00E00 monocarboxylic acid metabolic process (GO:0032787) 359 37 35.49 + 1.04 7.90E-01 1.00E00 cell morphogenesis (GO:0000902) 602 62 59.52 + 1.04 7.29E-01 1.00E00 cellular response to acid chemical (GO:0071229) 68 7 6.72 + 1.04 8.40E-01 1.00E00 signal release (GO:0023061) 136 14 13.45 + 1.04 8.86E-01 1.00E00 regulation of protein metabolic process (GO:0051246) 2130 219 210.60 + 1.04 5.59E-01 1.00E00 multicellular organismal process (GO:0032501) 4748 488 469.44 + 1.04 3.33E-01 1.00E00 positive regulation of endopeptidase activity (GO:0010950) 146 15 14.44 + 1.04 8.90E-01 1.00E00 regulation of systemic arterial blood pressure (GO:0003073) 78 8 7.71 + 1.04 8.50E-01 1.00E00 photoreceptor cell maintenance (GO:0045494) 39 4 3.86 + 1.04 7.93E-01 1.00E00 response to estradiol (GO:0032355) 39 4 3.86 + 1.04 7.93E-01 1.00E00 positive regulation of biomineral tissue development (GO:0070169) 39 4 3.86 + 1.04 7.93E-01 1.00E00 bone remodeling (GO:0046849) 39 4 3.86 + 1.04 7.93E-01 1.00E00 hair cycle process (GO:0022405) 78 8 7.71 + 1.04 8.50E-01 1.00E00 molting cycle process (GO:0022404) 78 8 7.71 + 1.04 8.50E-01 1.00E00 regulation of membrane potential (GO:0042391) 332 34 32.83 + 1.04 8.53E-01 1.00E00 protein homooligomerization (GO:0051260) 137 14 13.55 + 1.03 8.86E-01 1.00E00 negative regulation of neuron projection development (GO:0010977) 137 14 13.55 + 1.03 8.86E-01 1.00E00 positive regulation of ossification (GO:0045778) 49 5 4.84 + 1.03 8.14E-01 1.00E00 spindle localization (GO:0051653) 49 5 4.84 + 1.03 8.14E-01 1.00E00 olefinic compound metabolic process (GO:0120254) 49 5 4.84 + 1.03 8.14E-01 1.00E00 positive regulation of protein localization to membrane (GO:1905477) 98 10 9.69 + 1.03 8.66E-01 1.00E00 mesoderm morphogenesis (GO:0048332) 49 5 4.84 + 1.03 8.14E-01 1.00E00 regulation of cell projection organization (GO:0031344) 637 65 62.98 + 1.03 7.87E-01 1.00E00 negative regulation of dephosphorylation (GO:0035305) 49 5 4.84 + 1.03 8.14E-01 1.00E00 axon development (GO:0061564) 294 30 29.07 + 1.03 8.44E-01 1.00E00 positive regulation of organ growth (GO:0046622) 49 5 4.84 + 1.03 8.14E-01 1.00E00 negative regulation of canonical Wnt signaling pathway (GO:0090090) 108 11 10.68 + 1.03 8.72E-01 1.00E00 positive regulation of protein ubiquitination (GO:0031398) 108 11 10.68 + 1.03 8.72E-01 1.00E00 regulation of cell morphogenesis involved in differentiation (GO:0010769) 108 11 10.68 + 1.03 8.72E-01 1.00E00 regulation of cellular component size (GO:0032535) 344 35 34.01 + 1.03 8.56E-01 1.00E00 cardiac ventricle morphogenesis (GO:0003208) 59 6 5.83 + 1.03 8.30E-01 1.00E00 developmental process (GO:0032502) 4295 436 424.65 + 1.03 5.46E-01 1.00E00 activation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0006919) 69 7 6.82 + 1.03 8.42E-01 1.00E00 small GTPase mediated signal transduction (GO:0007264) 207 21 20.47 + 1.03 9.07E-01 1.00E00 nucleoside diphosphate metabolic process (GO:0009132) 69 7 6.82 + 1.03 8.42E-01 1.00E00 positive regulation of calcium ion transmembrane transport (GO:1904427) 69 7 6.82 + 1.03 8.42E-01 1.00E00 ameboidal-type cell migration (GO:0001667) 158 16 15.62 + 1.02 8.94E-01 1.00E00 carboxylic acid metabolic process (GO:0019752) 583 59 57.64 + 1.02 8.33E-01 1.00E00 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090100) 89 9 8.80 + 1.02 8.60E-01 1.00E00 multicellular organism development (GO:0007275) 3720 376 367.80 + 1.02 6.36E-01 1.00E00 negative regulation of metabolic process (GO:0009892) 2425 245 239.76 + 1.02 7.12E-01 1.00E00 regulation of protein localization (GO:0032880) 812 82 80.28 + 1.02 8.57E-01 1.00E00 inorganic cation transmembrane transport (GO:0098662) 327 33 32.33 + 1.02 9.26E-01 1.00E00 negative regulation of protein transport (GO:0051224) 119 12 11.77 + 1.02 8.78E-01 1.00E00 viral process (GO:0016032) 139 14 13.74 + 1.02 8.87E-01 1.00E00 phospholipid metabolic process (GO:0006644) 288 29 28.47 + 1.02 9.21E-01 1.00E00 protein dephosphorylation (GO:0006470) 149 15 14.73 + 1.02 8.91E-01 1.00E00 oxoacid metabolic process (GO:0043436) 596 60 58.93 + 1.02 8.89E-01 1.00E00 positive regulation of proteolysis (GO:0045862) 308 31 30.45 + 1.02 9.23E-01 1.00E00 neurogenesis (GO:0022008) 1183 119 116.96 + 1.02 8.40E-01 1.00E00 skin development (GO:0043588) 179 18 17.70 + 1.02 9.00E-01 1.00E00 lipid catabolic process (GO:0016042) 199 20 19.68 + 1.02 9.05E-01 1.00E00 regulation of cellular component biogenesis (GO:0044087) 867 87 85.72 + 1.01 8.61E-01 1.00E00 organic acid metabolic process (GO:0006082) 620 62 61.30 + 1.01 8.91E-01 1.00E00 amyloid-beta formation (GO:0034205) 10 1 .99 + 1.01 1.00E00 1.00E00 thalamus development (GO:0021794) 10 1 .99 + 1.01 1.00E00 1.00E00 glial cell fate commitment (GO:0021781) 10 1 .99 + 1.01 1.00E00 1.00E00 triglyceride catabolic process (GO:0019433) 10 1 .99 + 1.01 1.00E00 1.00E00 removal of superoxide radicals (GO:0019430) 10 1 .99 + 1.01 1.00E00 1.00E00 regulation of glomerular filtration (GO:0003093) 10 1 .99 + 1.01 1.00E00 1.00E00 alditol metabolic process (GO:0019400) 20 2 1.98 + 1.01 1.00E00 1.00E00 polyol catabolic process (GO:0046174) 20 2 1.98 + 1.01 1.00E00 1.00E00 multivesicular body sorting pathway (GO:0071985) 30 3 2.97 + 1.01 1.00E00 1.00E00 smooth muscle contraction (GO:0006939) 40 4 3.95 + 1.01 1.00E00 1.00E00 facial nerve morphogenesis (GO:0021610) 10 1 .99 + 1.01 1.00E00 1.00E00 cranial nerve structural organization (GO:0021604) 10 1 .99 + 1.01 1.00E00 1.00E00 heart trabecula formation (GO:0060347) 10 1 .99 + 1.01 1.00E00 1.00E00 positive regulation of biomineralization (GO:0110151) 40 4 3.95 + 1.01 1.00E00 1.00E00 transferrin transport (GO:0033572) 10 1 .99 + 1.01 1.00E00 1.00E00 ventricular system development (GO:0021591) 30 3 2.97 + 1.01 1.00E00 1.00E00 facial nerve development (GO:0021561) 10 1 .99 + 1.01 1.00E00 1.00E00 cell differentiation in spinal cord (GO:0021515) 30 3 2.97 + 1.01 1.00E00 1.00E00 positive regulation of autophagosome assembly (GO:2000786) 10 1 .99 + 1.01 1.00E00 1.00E00 alditol phosphate metabolic process (GO:0052646) 10 1 .99 + 1.01 1.00E00 1.00E00 metanephric nephron development (GO:0072210) 20 2 1.98 + 1.01 1.00E00 1.00E00 positive regulation of cardiac muscle cell differentiation (GO:2000727) 10 1 .99 + 1.01 1.00E00 1.00E00 regulation of apoptotic DNA fragmentation (GO:1902510) 10 1 .99 + 1.01 1.00E00 1.00E00 defense response to tumor cell (GO:0002357) 10 1 .99 + 1.01 1.00E00 1.00E00 response to ether (GO:0045472) 10 1 .99 + 1.01 1.00E00 1.00E00 receptor recycling (GO:0001881) 10 1 .99 + 1.01 1.00E00 1.00E00 SREBP signaling pathway (GO:0032933) 10 1 .99 + 1.01 1.00E00 1.00E00 regulation of activin receptor signaling pathway (GO:0032925) 20 2 1.98 + 1.01 1.00E00 1.00E00 mitotic cytokinetic process (GO:1902410) 20 2 1.98 + 1.01 1.00E00 1.00E00 protein targeting to lysosome (GO:0006622) 20 2 1.98 + 1.01 1.00E00 1.00E00 toxin transport (GO:1901998) 40 4 3.95 + 1.01 1.00E00 1.00E00 positive regulation of cell cycle checkpoint (GO:1901978) 10 1 .99 + 1.01 1.00E00 1.00E00 late endosome to vacuole transport (GO:0045324) 20 2 1.98 + 1.01 1.00E00 1.00E00 lysosome organization (GO:0007040) 70 7 6.92 + 1.01 1.00E00 1.00E00 angiotensin-activated signaling pathway (GO:0038166) 10 1 .99 + 1.01 1.00E00 1.00E00 Bergmann glial cell differentiation (GO:0060020) 10 1 .99 + 1.01 1.00E00 1.00E00 cellular response to sterol depletion (GO:0071501) 10 1 .99 + 1.01 1.00E00 1.00E00 integrated stress response signaling (GO:0140467) 10 1 .99 + 1.01 1.00E00 1.00E00 positive regulation of ATPase activity (GO:0032781) 40 4 3.95 + 1.01 1.00E00 1.00E00 vascular endothelial growth factor signaling pathway (GO:0038084) 20 2 1.98 + 1.01 1.00E00 1.00E00 positive regulation of interleukin-5 production (GO:0032754) 10 1 .99 + 1.01 1.00E00 1.00E00 cell migration involved in sprouting angiogenesis (GO:0002042) 20 2 1.98 + 1.01 1.00E00 1.00E00 cellular detoxification (GO:1990748) 30 3 2.97 + 1.01 1.00E00 1.00E00 meiotic sister chromatid segregation (GO:0045144) 10 1 .99 + 1.01 1.00E00 1.00E00 vasculogenesis (GO:0001570) 70 7 6.92 + 1.01 1.00E00 1.00E00 lipid import into cell (GO:0140354) 10 1 .99 + 1.01 1.00E00 1.00E00 positive regulation of endothelial cell apoptotic process (GO:2000353) 20 2 1.98 + 1.01 1.00E00 1.00E00 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:1902166) 10 1 .99 + 1.01 1.00E00 1.00E00 plasma membrane fusion (GO:0045026) 10 1 .99 + 1.01 1.00E00 1.00E00 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning (GO:1901620) 10 1 .99 + 1.01 1.00E00 1.00E00 negative regulation of protein exit from endoplasmic reticulum (GO:0070862) 10 1 .99 + 1.01 1.00E00 1.00E00 long-chain fatty acid import into cell (GO:0044539) 10 1 .99 + 1.01 1.00E00 1.00E00 cellular response to leucine (GO:0071233) 10 1 .99 + 1.01 1.00E00 1.00E00 negative regulation of excitatory postsynaptic potential (GO:0090394) 10 1 .99 + 1.01 1.00E00 1.00E00 histamine transport (GO:0051608) 10 1 .99 + 1.01 1.00E00 1.00E00 venous blood vessel morphogenesis (GO:0048845) 10 1 .99 + 1.01 1.00E00 1.00E00 spindle assembly involved in meiosis (GO:0090306) 10 1 .99 + 1.01 1.00E00 1.00E00 peptidyl-arginine modification (GO:0018195) 20 2 1.98 + 1.01 1.00E00 1.00E00 nucleoside diphosphate phosphorylation (GO:0006165) 50 5 4.94 + 1.01 1.00E00 1.00E00 regulation of growth rate (GO:0040009) 10 1 .99 + 1.01 1.00E00 1.00E00 positive regulation of cholesterol metabolic process (GO:0090205) 10 1 .99 + 1.01 1.00E00 1.00E00 negative regulation of stress fiber assembly (GO:0051497) 30 3 2.97 + 1.01 1.00E00 1.00E00 positive regulation of meiotic cell cycle (GO:0051446) 20 2 1.98 + 1.01 1.00E00 1.00E00 proximal/distal pattern formation (GO:0009954) 20 2 1.98 + 1.01 1.00E00 1.00E00 regulation of store-operated calcium channel activity (GO:1901339) 10 1 .99 + 1.01 1.00E00 1.00E00 regulation of nitric-oxide synthase activity (GO:0050999) 30 3 2.97 + 1.01 1.00E00 1.00E00 histone H3-K36 demethylation (GO:0070544) 10 1 .99 + 1.01 1.00E00 1.00E00 positive regulation of muscle organ development (GO:0048636) 20 2 1.98 + 1.01 1.00E00 1.00E00 sulfur compound catabolic process (GO:0044273) 20 2 1.98 + 1.01 1.00E00 1.00E00 regulation of anatomical structure size (GO:0090066) 460 46 45.48 + 1.01 9.37E-01 1.00E00 response to mitochondrial depolarisation (GO:0098780) 20 2 1.98 + 1.01 1.00E00 1.00E00 linoleic acid metabolic process (GO:0043651) 10 1 .99 + 1.01 1.00E00 1.00E00 dicarboxylic acid catabolic process (GO:0043649) 10 1 .99 + 1.01 1.00E00 1.00E00 regulation of respiratory system process (GO:0044065) 10 1 .99 + 1.01 1.00E00 1.00E00 regulation of response to food (GO:0032095) 10 1 .99 + 1.01 1.00E00 1.00E00 response to food (GO:0032094) 10 1 .99 + 1.01 1.00E00 1.00E00 regulation of synaptic vesicle cycle (GO:0098693) 10 1 .99 + 1.01 1.00E00 1.00E00 cellular response to nerve growth factor stimulus (GO:1990090) 30 3 2.97 + 1.01 1.00E00 1.00E00 response to nerve growth factor (GO:1990089) 30 3 2.97 + 1.01 1.00E00 1.00E00 meiotic sister chromatid cohesion (GO:0051177) 10 1 .99 + 1.01 1.00E00 1.00E00 blood vessel endothelial cell migration (GO:0043534) 30 3 2.97 + 1.01 1.00E00 1.00E00 regulation of defense response to virus by host (GO:0050691) 40 4 3.95 + 1.01 1.00E00 1.00E00 homocysteine metabolic process (GO:0050667) 10 1 .99 + 1.01 1.00E00 1.00E00 positive regulation of plasma membrane bounded cell projection assembly (GO:0120034) 100 10 9.89 + 1.01 8.68E-01 1.00E00 RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) 10 1 .99 + 1.01 1.00E00 1.00E00 positive regulation of renal sodium excretion (GO:0035815) 10 1 .99 + 1.01 1.00E00 1.00E00 sequestering of actin monomers (GO:0042989) 10 1 .99 + 1.01 1.00E00 1.00E00 elastic fiber assembly (GO:0048251) 10 1 .99 + 1.01 1.00E00 1.00E00 deadenylation-dependent decapping of nuclear-transcribed mRNA (GO:0000290) 10 1 .99 + 1.01 1.00E00 1.00E00 negative regulation of cell killing (GO:0031342) 30 3 2.97 + 1.01 1.00E00 1.00E00 NAD biosynthetic process (GO:0009435) 10 1 .99 + 1.01 1.00E00 1.00E00 lysosomal protein catabolic process (GO:1905146) 10 1 .99 + 1.01 1.00E00 1.00E00 response to leucine (GO:0043201) 10 1 .99 + 1.01 1.00E00 1.00E00 drinking behavior (GO:0042756) 10 1 .99 + 1.01 1.00E00 1.00E00 protein localization to endosome (GO:0036010) 10 1 .99 + 1.01 1.00E00 1.00E00 rRNA pseudouridine synthesis (GO:0031118) 10 1 .99 + 1.01 1.00E00 1.00E00 negative regulation of neurotransmitter secretion (GO:0046929) 10 1 .99 + 1.01 1.00E00 1.00E00 potassium ion export across plasma membrane (GO:0097623) 10 1 .99 + 1.01 1.00E00 1.00E00 female genitalia development (GO:0030540) 10 1 .99 + 1.01 1.00E00 1.00E00 positive regulation of substrate adhesion-dependent cell spreading (GO:1900026) 40 4 3.95 + 1.01 1.00E00 1.00E00 regulation of protein complex stability (GO:0061635) 10 1 .99 + 1.01 1.00E00 1.00E00 positive regulation of receptor clustering (GO:1903911) 10 1 .99 + 1.01 1.00E00 1.00E00 membrane depolarization during cardiac muscle cell action potential (GO:0086012) 10 1 .99 + 1.01 1.00E00 1.00E00 ventricular cardiac muscle cell action potential (GO:0086005) 10 1 .99 + 1.01 1.00E00 1.00E00 lipid phosphorylation (GO:0046834) 10 1 .99 + 1.01 1.00E00 1.00E00 protein localization to cell-cell junction (GO:0150105) 20 2 1.98 + 1.01 1.00E00 1.00E00 ribonucleoside catabolic process (GO:0042454) 10 1 .99 + 1.01 1.00E00 1.00E00 negative regulation of myotube differentiation (GO:0010832) 10 1 .99 + 1.01 1.00E00 1.00E00 regulation of viral transcription (GO:0046782) 20 2 1.98 + 1.01 1.00E00 1.00E00 regulation of cGMP-mediated signaling (GO:0010752) 10 1 .99 + 1.01 1.00E00 1.00E00 positive regulation of collagen metabolic process (GO:0010714) 30 3 2.97 + 1.01 1.00E00 1.00E00 maintenance of gastrointestinal epithelium (GO:0030277) 10 1 .99 + 1.01 1.00E00 1.00E00 regulation of alkaline phosphatase activity (GO:0010692) 10 1 .99 + 1.01 1.00E00 1.00E00 mitochondrial outer membrane permeabilization (GO:0097345) 10 1 .99 + 1.01 1.00E00 1.00E00 response to cocaine (GO:0042220) 30 3 2.97 + 1.01 1.00E00 1.00E00 positive regulation of striated muscle cell apoptotic process (GO:0010663) 20 2 1.98 + 1.01 1.00E00 1.00E00 regulation of striated muscle cell apoptotic process (GO:0010662) 50 5 4.94 + 1.01 1.00E00 1.00E00 male sex determination (GO:0030238) 10 1 .99 + 1.01 1.00E00 1.00E00 semicircular canal development (GO:0060872) 10 1 .99 + 1.01 1.00E00 1.00E00 sphingoid biosynthetic process (GO:0046520) 10 1 .99 + 1.01 1.00E00 1.00E00 sphingosine biosynthetic process (GO:0046512) 10 1 .99 + 1.01 1.00E00 1.00E00 self proteolysis (GO:0097264) 10 1 .99 + 1.01 1.00E00 1.00E00 estrogen metabolic process (GO:0008210) 20 2 1.98 + 1.01 1.00E00 1.00E00 regulation of cilium movement (GO:0003352) 20 2 1.98 + 1.01 1.00E00 1.00E00 glycerophospholipid biosynthetic process (GO:0046474) 140 14 13.84 + 1.01 8.88E-01 1.00E00 chorion development (GO:0060717) 10 1 .99 + 1.01 1.00E00 1.00E00 microtubule anchoring at centrosome (GO:0034454) 10 1 .99 + 1.01 1.00E00 1.00E00 GABAergic neuron differentiation (GO:0097154) 10 1 .99 + 1.01 1.00E00 1.00E00 mesenchymal cell proliferation (GO:0010463) 10 1 .99 + 1.01 1.00E00 1.00E00 negative regulation of heart rate (GO:0010459) 10 1 .99 + 1.01 1.00E00 1.00E00 negative regulation of calcium ion-dependent exocytosis (GO:0045955) 10 1 .99 + 1.01 1.00E00 1.00E00 negative regulation of natural killer cell mediated cytotoxicity (GO:0045953) 20 2 1.98 + 1.01 1.00E00 1.00E00 multinuclear osteoclast differentiation (GO:0072674) 10 1 .99 + 1.01 1.00E00 1.00E00 lipid droplet organization (GO:0034389) 20 2 1.98 + 1.01 1.00E00 1.00E00 mammary gland duct morphogenesis (GO:0060603) 30 3 2.97 + 1.01 1.00E00 1.00E00 cellular response to thyroid hormone stimulus (GO:0097067) 10 1 .99 + 1.01 1.00E00 1.00E00 positive regulation of striated muscle tissue development (GO:0045844) 20 2 1.98 + 1.01 1.00E00 1.00E00 hypothalamus development (GO:0021854) 10 1 .99 + 1.01 1.00E00 1.00E00 aging (GO:0007568) 130 13 12.85 + 1.01 8.84E-01 1.00E00 positive regulation of protein maturation (GO:1903319) 20 2 1.98 + 1.01 1.00E00 1.00E00 endocardial cushion development (GO:0003197) 40 4 3.95 + 1.01 1.00E00 1.00E00 lytic vacuole organization (GO:0080171) 70 7 6.92 + 1.01 1.00E00 1.00E00 multi-multicellular organism process (GO:0044706) 110 11 10.88 + 1.01 8.74E-01 1.00E00 anatomical structure development (GO:0048856) 3972 397 392.72 + 1.01 8.05E-01 1.00E00 regulation of plasma membrane bounded cell projection organization (GO:0120035) 622 62 61.50 + 1.01 9.46E-01 1.00E00 positive regulation of establishment of protein localization (GO:1904951) 291 29 28.77 + 1.01 9.22E-01 1.00E00 muscle organ development (GO:0007517) 211 21 20.86 + 1.01 9.08E-01 1.00E00 positive regulation of cell projection organization (GO:0031346) 372 37 36.78 + 1.01 9.30E-01 1.00E00 connective tissue development (GO:0061448) 171 17 16.91 + 1.01 1.00E00 1.00E00 anatomical structure formation involved in morphogenesis (GO:0048646) 775 77 76.63 + 1.00 9.51E-01 1.00E00 maintenance of location (GO:0051235) 151 15 14.93 + 1.00 1.00E00 1.00E00 biological_process (GO:0008150) 14248 1413 1408.72 + 1.00 6.11E-01 1.00E00 regulation of cellular component organization (GO:0051128) 2141 212 211.68 + 1.00 9.69E-01 1.00E00 positive regulation of protein catabolic process (GO:0045732) 202 20 19.97 + 1.00 1.00E00 1.00E00 positive regulation of proteasomal protein catabolic process (GO:1901800) 101 10 9.99 + 1.00 1.00E00 1.00E00 regulation of growth (GO:0040008) 586 58 57.94 + 1.00 1.00E00 1.00E00 positive regulation of cellular component organization (GO:0051130) 1053 104 104.11 - 1.00 1.00E00 1.00E00 response to abiotic stimulus (GO:0009628) 800 79 79.10 - 1.00 1.00E00 1.00E00 negative regulation of ERK1 and ERK2 cascade (GO:0070373) 71 7 7.02 - 1.00 1.00E00 1.00E00 regulation of cellular pH (GO:0030641) 71 7 7.02 - 1.00 1.00E00 1.00E00 long-chain fatty acid metabolic process (GO:0001676) 61 6 6.03 - .99 1.00E00 1.00E00 positive regulation of macroautophagy (GO:0016239) 61 6 6.03 - .99 1.00E00 1.00E00 cellular amino acid catabolic process (GO:0009063) 61 6 6.03 - .99 1.00E00 1.00E00 negative regulation of cell cycle G1/S phase transition (GO:1902807) 61 6 6.03 - .99 1.00E00 1.00E00 dicarboxylic acid transport (GO:0006835) 51 5 5.04 - .99 1.00E00 1.00E00 xenobiotic metabolic process (GO:0006805) 51 5 5.04 - .99 1.00E00 1.00E00 regulation of actomyosin structure organization (GO:0110020) 102 10 10.08 - .99 1.00E00 1.00E00 regulation of neurotransmitter receptor activity (GO:0099601) 51 5 5.04 - .99 1.00E00 1.00E00 regulation of myelination (GO:0031641) 51 5 5.04 - .99 1.00E00 1.00E00 negative regulation of muscle cell differentiation (GO:0051148) 51 5 5.04 - .99 1.00E00 1.00E00 insulin receptor signaling pathway (GO:0008286) 51 5 5.04 - .99 1.00E00 1.00E00 regulation of protein targeting (GO:1903533) 51 5 5.04 - .99 1.00E00 1.00E00 substrate adhesion-dependent cell spreading (GO:0034446) 51 5 5.04 - .99 1.00E00 1.00E00 mammary gland epithelium development (GO:0061180) 51 5 5.04 - .99 1.00E00 1.00E00 cellular component morphogenesis (GO:0032989) 490 48 48.45 - .99 1.00E00 1.00E00 regulation of establishment of protein localization (GO:0070201) 490 48 48.45 - .99 1.00E00 1.00E00 phospholipid biosynthetic process (GO:0008654) 184 18 18.19 - .99 1.00E00 1.00E00 Ras protein signal transduction (GO:0007265) 133 13 13.15 - .99 1.00E00 1.00E00 negative regulation of Wnt signaling pathway (GO:0030178) 133 13 13.15 - .99 1.00E00 1.00E00 cellular process (GO:0009987) 11239 1097 1111.22 - .99 4.05E-01 1.00E00 polyol biosynthetic process (GO:0046173) 41 4 4.05 - .99 1.00E00 1.00E00 homotypic cell-cell adhesion (GO:0034109) 41 4 4.05 - .99 1.00E00 1.00E00 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (GO:0007193) 41 4 4.05 - .99 1.00E00 1.00E00 glycosphingolipid metabolic process (GO:0006687) 41 4 4.05 - .99 1.00E00 1.00E00 response to estrogen (GO:0043627) 41 4 4.05 - .99 1.00E00 1.00E00 ovulation cycle (GO:0042698) 41 4 4.05 - .99 1.00E00 1.00E00 hair cycle (GO:0042633) 82 8 8.11 - .99 1.00E00 1.00E00 negative regulation of histone modification (GO:0031057) 41 4 4.05 - .99 1.00E00 1.00E00 molting cycle (GO:0042303) 82 8 8.11 - .99 1.00E00 1.00E00 tissue regeneration (GO:0042246) 41 4 4.05 - .99 1.00E00 1.00E00 neuromuscular junction development (GO:0007528) 41 4 4.05 - .99 1.00E00 1.00E00 regulation of cellular localization (GO:0060341) 769 75 76.03 - .99 9.51E-01 1.00E00 cell development (GO:0048468) 1395 136 137.93 - .99 9.25E-01 1.00E00 cell morphogenesis involved in differentiation (GO:0000904) 462 45 45.68 - .99 1.00E00 1.00E00 regulation of neurotransmitter levels (GO:0001505) 185 18 18.29 - .98 1.00E00 1.00E00 vesicle fusion (GO:0006906) 72 7 7.12 - .98 1.00E00 1.00E00 hormone-mediated signaling pathway (GO:0009755) 72 7 7.12 - .98 1.00E00 1.00E00 negative regulation of macromolecule metabolic process (GO:0010605) 2233 217 220.78 - .98 8.18E-01 1.00E00 response to peptide hormone (GO:0043434) 227 22 22.44 - .98 1.00E00 1.00E00 positive regulation of catabolic process (GO:0009896) 444 43 43.90 - .98 1.00E00 1.00E00 nerve development (GO:0021675) 62 6 6.13 - .98 1.00E00 1.00E00 binding of sperm to zona pellucida (GO:0007339) 31 3 3.07 - .98 1.00E00 1.00E00 receptor signaling pathway via JAK-STAT (GO:0007259) 31 3 3.07 - .98 1.00E00 1.00E00 positive regulation of response to endoplasmic reticulum stress (GO:1905898) 31 3 3.07 - .98 1.00E00 1.00E00 regulation of cholesterol metabolic process (GO:0090181) 31 3 3.07 - .98 1.00E00 1.00E00 positive regulation of actin filament bundle assembly (GO:0032233) 62 6 6.13 - .98 1.00E00 1.00E00 nucleoside phosphate catabolic process (GO:1901292) 62 6 6.13 - .98 1.00E00 1.00E00 negative regulation of establishment of protein localization (GO:1904950) 124 12 12.26 - .98 1.00E00 1.00E00 positive regulation of morphogenesis of an epithelium (GO:1905332) 31 3 3.07 - .98 1.00E00 1.00E00 response to alkaloid (GO:0043279) 62 6 6.13 - .98 1.00E00 1.00E00 positive regulation of protein-containing complex disassembly (GO:0043243) 31 3 3.07 - .98 1.00E00 1.00E00 purine ribonucleoside monophosphate metabolic process (GO:0009167) 31 3 3.07 - .98 1.00E00 1.00E00 receptor signaling pathway via STAT (GO:0097696) 31 3 3.07 - .98 1.00E00 1.00E00 negative regulation of macroautophagy (GO:0016242) 31 3 3.07 - .98 1.00E00 1.00E00 positive regulation of cell-substrate junction organization (GO:0150117) 31 3 3.07 - .98 1.00E00 1.00E00 regulation of cholesterol efflux (GO:0010874) 31 3 3.07 - .98 1.00E00 1.00E00 negative regulation of epithelial to mesenchymal transition (GO:0010719) 31 3 3.07 - .98 1.00E00 1.00E00 response to antibiotic (GO:0046677) 31 3 3.07 - .98 1.00E00 1.00E00 negative regulation of striated muscle cell apoptotic process (GO:0010664) 31 3 3.07 - .98 1.00E00 1.00E00 olfactory lobe development (GO:0021988) 31 3 3.07 - .98 1.00E00 1.00E00 regulation of TOR signaling (GO:0032006) 93 9 9.20 - .98 1.00E00 1.00E00 positive regulation of cellular metabolic process (GO:0031325) 2654 256 262.40 - .98 6.94E-01 1.00E00 endomembrane system organization (GO:0010256) 394 38 38.96 - .98 1.00E00 1.00E00 positive regulation of protein-containing complex assembly (GO:0031334) 197 19 19.48 - .98 1.00E00 1.00E00 vacuolar transport (GO:0007034) 135 13 13.35 - .97 1.00E00 1.00E00 negative regulation of fat cell differentiation (GO:0045599) 52 5 5.14 - .97 1.00E00 1.00E00 regulation of synaptic transmission, glutamatergic (GO:0051966) 52 5 5.14 - .97 1.00E00 1.00E00 regulation of circadian rhythm (GO:0042752) 104 10 10.28 - .97 1.00E00 1.00E00 determination of heart left/right asymmetry (GO:0061371) 52 5 5.14 - .97 1.00E00 1.00E00 peptidyl-serine phosphorylation (GO:0018105) 177 17 17.50 - .97 1.00E00 1.00E00 positive regulation of autophagy (GO:0010508) 125 12 12.36 - .97 1.00E00 1.00E00 peptidyl-threonine phosphorylation (GO:0018107) 73 7 7.22 - .97 1.00E00 1.00E00 positive regulation of cellular catabolic process (GO:0031331) 386 37 38.16 - .97 9.31E-01 1.00E00 positive regulation of supramolecular fiber organization (GO:1902905) 167 16 16.51 - .97 1.00E00 1.00E00 regulation of macroautophagy (GO:0016241) 94 9 9.29 - .97 1.00E00 1.00E00 hormone metabolic process (GO:0042445) 94 9 9.29 - .97 1.00E00 1.00E00 urogenital system development (GO:0001655) 282 27 27.88 - .97 1.00E00 1.00E00 tube development (GO:0035295) 795 76 78.60 - .97 8.08E-01 1.00E00 inner ear development (GO:0048839) 157 15 15.52 - .97 1.00E00 1.00E00 regulation of metabolic process (GO:0019222) 5276 503 521.65 - .96 3.45E-01 1.00E00 regulation of bicellular tight junction assembly (GO:2000810) 21 2 2.08 - .96 1.00E00 1.00E00 cell differentiation in hindbrain (GO:0021533) 21 2 2.08 - .96 1.00E00 1.00E00 spinal cord motor neuron differentiation (GO:0021522) 21 2 2.08 - .96 1.00E00 1.00E00 negative regulation of double-strand break repair (GO:2000780) 21 2 2.08 - .96 1.00E00 1.00E00 negative regulation of posttranscriptional gene silencing (GO:0060149) 21 2 2.08 - .96 1.00E00 1.00E00 nephron tubule development (GO:0072080) 63 6 6.23 - .96 1.00E00 1.00E00 positive regulation of muscle tissue development (GO:1901863) 21 2 2.08 - .96 1.00E00 1.00E00 NIK/NF-kappaB signaling (GO:0038061) 21 2 2.08 - .96 1.00E00 1.00E00 glycogen metabolic process (GO:0005977) 42 4 4.15 - .96 1.00E00 1.00E00 glycosyl compound catabolic process (GO:1901658) 21 2 2.08 - .96 1.00E00 1.00E00 positive regulation of signaling receptor activity (GO:2000273) 42 4 4.15 - .96 1.00E00 1.00E00 regulation of protein localization to cell surface (GO:2000008) 42 4 4.15 - .96 1.00E00 1.00E00 cellular aldehyde metabolic process (GO:0006081) 42 4 4.15 - .96 1.00E00 1.00E00 cellular glucan metabolic process (GO:0006073) 42 4 4.15 - .96 1.00E00 1.00E00 establishment of protein localization to mitochondrial membrane (GO:0090151) 21 2 2.08 - .96 1.00E00 1.00E00 regulation of vacuole organization (GO:0044088) 42 4 4.15 - .96 1.00E00 1.00E00 glucan metabolic process (GO:0044042) 42 4 4.15 - .96 1.00E00 1.00E00 regulation of postsynaptic neurotransmitter receptor internalization (GO:0099149) 21 2 2.08 - .96 1.00E00 1.00E00 regulation of muscle adaptation (GO:0043502) 84 8 8.31 - .96 1.00E00 1.00E00 metallo-sulfur cluster assembly (GO:0031163) 21 2 2.08 - .96 1.00E00 1.00E00 iron-sulfur cluster assembly (GO:0016226) 21 2 2.08 - .96 1.00E00 1.00E00 regulation of striated muscle tissue development (GO:0016202) 42 4 4.15 - .96 1.00E00 1.00E00 negative regulation of gene silencing by RNA (GO:0060967) 21 2 2.08 - .96 1.00E00 1.00E00 regulation of epidermal growth factor receptor signaling pathway (GO:0042058) 63 6 6.23 - .96 1.00E00 1.00E00 regulation of immune response to tumor cell (GO:0002837) 21 2 2.08 - .96 1.00E00 1.00E00 regulation of response to tumor cell (GO:0002834) 21 2 2.08 - .96 1.00E00 1.00E00 atrioventricular valve morphogenesis (GO:0003181) 21 2 2.08 - .96 1.00E00 1.00E00 outflow tract septum morphogenesis (GO:0003148) 21 2 2.08 - .96 1.00E00 1.00E00 post-embryonic development (GO:0009791) 105 10 10.38 - .96 1.00E00 1.00E00 forebrain development (GO:0030900) 284 27 28.08 - .96 9.20E-01 1.00E00 generation of neurons (GO:0048699) 1065 101 105.30 - .96 7.10E-01 1.00E00 female gamete generation (GO:0007292) 116 11 11.47 - .96 1.00E00 1.00E00 cellular response to organic cyclic compound (GO:0071407) 306 29 30.25 - .96 9.23E-01 1.00E00 cholesterol metabolic process (GO:0008203) 95 9 9.39 - .96 1.00E00 1.00E00 regulation of gene expression (GO:0010468) 3748 355 370.57 - .96 3.77E-01 1.00E00 anatomical structure morphogenesis (GO:0009653) 1774 168 175.40 - .96 6.12E-01 1.00E00 response to insulin (GO:0032868) 148 14 14.63 - .96 1.00E00 1.00E00 regulation of dendritic spine development (GO:0060998) 74 7 7.32 - .96 1.00E00 1.00E00 skeletal system development (GO:0001501) 381 36 37.67 - .96 8.62E-01 1.00E00 regulation of cell cycle G1/S phase transition (GO:1902806) 127 12 12.56 - .96 1.00E00 1.00E00 secondary alcohol metabolic process (GO:1902652) 106 10 10.48 - .95 1.00E00 1.00E00 positive regulation of stress fiber assembly (GO:0051496) 53 5 5.24 - .95 1.00E00 1.00E00 nucleoside triphosphate biosynthetic process (GO:0009142) 53 5 5.24 - .95 1.00E00 1.00E00 nucleotide phosphorylation (GO:0046939) 53 5 5.24 - .95 1.00E00 1.00E00 membrane fusion (GO:0061025) 106 10 10.48 - .95 1.00E00 1.00E00 tissue development (GO:0009888) 1283 121 126.85 - .95 6.26E-01 1.00E00 positive regulation of cell cycle (GO:0045787) 276 26 27.29 - .95 9.19E-01 1.00E00 regulation of neuron differentiation (GO:0045664) 170 16 16.81 - .95 1.00E00 1.00E00 cell morphogenesis involved in neuron differentiation (GO:0048667) 351 33 34.70 - .95 8.57E-01 1.00E00 regulation of macromolecule metabolic process (GO:0060255) 4885 459 482.99 - .95 2.10E-01 1.00E00 membrane depolarization (GO:0051899) 32 3 3.16 - .95 1.00E00 1.00E00 columnar/cuboidal epithelial cell development (GO:0002066) 32 3 3.16 - .95 1.00E00 1.00E00 positive regulation of mesenchymal cell proliferation (GO:0002053) 32 3 3.16 - .95 1.00E00 1.00E00 bicellular tight junction assembly (GO:0070830) 32 3 3.16 - .95 1.00E00 1.00E00 response to retinoic acid (GO:0032526) 64 6 6.33 - .95 1.00E00 1.00E00 regulation of hematopoietic progenitor cell differentiation (GO:1901532) 32 3 3.16 - .95 1.00E00 1.00E00 genitalia development (GO:0048806) 32 3 3.16 - .95 1.00E00 1.00E00 intracellular pH reduction (GO:0051452) 32 3 3.16 - .95 1.00E00 1.00E00 response to axon injury (GO:0048678) 32 3 3.16 - .95 1.00E00 1.00E00 regulation of calcium ion-dependent exocytosis (GO:0017158) 32 3 3.16 - .95 1.00E00 1.00E00 purine nucleoside monophosphate metabolic process (GO:0009126) 32 3 3.16 - .95 1.00E00 1.00E00 negative regulation of protein dephosphorylation (GO:0035308) 32 3 3.16 - .95 1.00E00 1.00E00 positive regulation of histone acetylation (GO:0035066) 32 3 3.16 - .95 1.00E00 1.00E00 insulin secretion (GO:0030073) 32 3 3.16 - .95 1.00E00 1.00E00 negative regulation of JNK cascade (GO:0046329) 32 3 3.16 - .95 1.00E00 1.00E00 primary alcohol metabolic process (GO:0034308) 32 3 3.16 - .95 1.00E00 1.00E00 positive regulation of ubiquitin-dependent protein catabolic process (GO:2000060) 96 9 9.49 - .95 1.00E00 1.00E00 positive regulation of nitrogen compound metabolic process (GO:0051173) 2464 231 243.62 - .95 4.18E-01 1.00E00 positive regulation of cell cycle process (GO:0090068) 203 19 20.07 - .95 9.06E-01 1.00E00 vesicle localization (GO:0051648) 139 13 13.74 - .95 1.00E00 1.00E00 cell-cell signaling (GO:0007267) 589 55 58.24 - .94 7.26E-01 1.00E00 glycolipid metabolic process (GO:0006664) 75 7 7.42 - .94 1.00E00 1.00E00 cellular response to steroid hormone stimulus (GO:0071383) 75 7 7.42 - .94 1.00E00 1.00E00 cellular lipid catabolic process (GO:0044242) 150 14 14.83 - .94 1.00E00 1.00E00 glycerophospholipid metabolic process (GO:0006650) 225 21 22.25 - .94 9.11E-01 1.00E00 alcohol metabolic process (GO:0006066) 225 21 22.25 - .94 9.11E-01 1.00E00 regulation of neuron projection development (GO:0010975) 461 43 45.58 - .94 8.12E-01 1.00E00 sulfur compound metabolic process (GO:0006790) 236 22 23.33 - .94 9.13E-01 1.00E00 presynaptic endocytosis (GO:0140238) 43 4 4.25 - .94 1.00E00 1.00E00 establishment of vesicle localization (GO:0051650) 129 12 12.75 - .94 1.00E00 1.00E00 synaptic vesicle endocytosis (GO:0048488) 43 4 4.25 - .94 1.00E00 1.00E00 mRNA stabilization (GO:0048255) 43 4 4.25 - .94 1.00E00 1.00E00 cardiac conduction (GO:0061337) 43 4 4.25 - .94 1.00E00 1.00E00 nervous system development (GO:0007399) 1657 154 163.83 - .94 4.59E-01 1.00E00 organonitrogen compound metabolic process (GO:1901564) 3693 343 365.13 - .94 2.05E-01 1.00E00 cell part morphogenesis (GO:0032990) 420 39 41.53 - .94 8.04E-01 1.00E00 regulation of cellular protein localization (GO:1903827) 517 48 51.12 - .94 7.65E-01 1.00E00 protein phosphorylation (GO:0006468) 582 54 57.54 - .94 7.24E-01 1.00E00 regulation of axon extension (GO:0030516) 97 9 9.59 - .94 1.00E00 1.00E00 nervous system process (GO:0050877) 787 73 77.81 - .94 6.25E-01 1.00E00 positive regulation of cellular component biogenesis (GO:0044089) 453 42 44.79 - .94 7.50E-01 1.00E00 regulation of substrate adhesion-dependent cell spreading (GO:1900024) 54 5 5.34 - .94 1.00E00 1.00E00 regulation of extent of cell growth (GO:0061387) 108 10 10.68 - .94 1.00E00 1.00E00 regulation of histone acetylation (GO:0035065) 54 5 5.34 - .94 1.00E00 1.00E00 inorganic ion transmembrane transport (GO:0098660) 357 33 35.30 - .93 7.88E-01 1.00E00 brain development (GO:0007420) 498 46 49.24 - .93 7.03E-01 1.00E00 regulation of peptidyl-lysine acetylation (GO:2000756) 65 6 6.43 - .93 1.00E00 1.00E00 columnar/cuboidal epithelial cell differentiation (GO:0002065) 65 6 6.43 - .93 1.00E00 1.00E00 regulation of steroid biosynthetic process (GO:0050810) 65 6 6.43 - .93 1.00E00 1.00E00 organelle membrane fusion (GO:0090174) 76 7 7.51 - .93 1.00E00 1.00E00 epithelium migration (GO:0090132) 76 7 7.51 - .93 1.00E00 1.00E00 carbohydrate derivative metabolic process (GO:1901135) 684 63 67.63 - .93 6.47E-01 1.00E00 negative regulation of cellular metabolic process (GO:0031324) 2052 189 202.88 - .93 3.40E-01 1.00E00 epithelial cell migration (GO:0010631) 76 7 7.51 - .93 1.00E00 1.00E00 liposaccharide metabolic process (GO:1903509) 76 7 7.51 - .93 1.00E00 1.00E00 protein localization to cell periphery (GO:1990778) 228 21 22.54 - .93 8.24E-01 1.00E00 glycosylation (GO:0070085) 174 16 17.20 - .93 8.99E-01 1.00E00 lung development (GO:0030324) 174 16 17.20 - .93 8.99E-01 1.00E00 regulation of cellular response to stress (GO:0080135) 588 54 58.14 - .93 6.73E-01 1.00E00 cellular component disassembly (GO:0022411) 207 19 20.47 - .93 9.07E-01 1.00E00 protein folding (GO:0006457) 142 13 14.04 - .93 8.88E-01 1.00E00 regulation of axonogenesis (GO:0050770) 153 14 15.13 - .93 8.92E-01 1.00E00 small molecule metabolic process (GO:0044281) 1148 105 113.50 - .93 4.72E-01 1.00E00 organic substance transport (GO:0071702) 1554 142 153.65 - .92 3.70E-01 1.00E00 renal system development (GO:0072001) 252 23 24.92 - .92 8.31E-01 1.00E00 regulation of catabolic process (GO:0009894) 811 74 80.18 - .92 5.46E-01 1.00E00 neuron projection morphogenesis (GO:0048812) 384 35 37.97 - .92 7.29E-01 1.00E00 Unclassified (UNCLASSIFIED) 549 50 54.28 - .92 6.11E-01 1.00E00 regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044) 33 3 3.26 - .92 1.00E00 1.00E00 cellular response to retinoic acid (GO:0071300) 33 3 3.26 - .92 1.00E00 1.00E00 cell projection morphogenesis (GO:0048858) 396 36 39.15 - .92 6.71E-01 1.00E00 establishment of mitotic spindle localization (GO:0040001) 33 3 3.26 - .92 1.00E00 1.00E00 regulation of establishment of planar polarity (GO:0090175) 33 3 3.26 - .92 1.00E00 1.00E00 selective autophagy (GO:0061912) 33 3 3.26 - .92 1.00E00 1.00E00 negative regulation of DNA repair (GO:0045738) 22 2 2.18 - .92 1.00E00 1.00E00 negative regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0045736) 22 2 2.18 - .92 1.00E00 1.00E00 embryonic skeletal joint development (GO:0072498) 11 1 1.09 - .92 1.00E00 1.00E00 aldehyde catabolic process (GO:0046185) 11 1 1.09 - .92 1.00E00 1.00E00 response to sterol depletion (GO:0006991) 11 1 1.09 - .92 1.00E00 1.00E00 vesicle coating (GO:0006901) 11 1 1.09 - .92 1.00E00 1.00E00 negative regulation of erythrocyte differentiation (GO:0045647) 11 1 1.09 - .92 1.00E00 1.00E00 glycolipid catabolic process (GO:0019377) 11 1 1.09 - .92 1.00E00 1.00E00 regulation of SMAD protein signal transduction (GO:0060390) 22 2 2.18 - .92 1.00E00 1.00E00 Golgi to endosome transport (GO:0006895) 11 1 1.09 - .92 1.00E00 1.00E00 nucleotide transport (GO:0006862) 22 2 2.18 - .92 1.00E00 1.00E00 positive regulation of extracellular matrix organization (GO:1903055) 22 2 2.18 - .92 1.00E00 1.00E00 regulation of osteoclast development (GO:2001204) 11 1 1.09 - .92 1.00E00 1.00E00 renal system process involved in regulation of blood volume (GO:0001977) 11 1 1.09 - .92 1.00E00 1.00E00 startle response (GO:0001964) 22 2 2.18 - .92 1.00E00 1.00E00 spinal cord dorsal/ventral patterning (GO:0021513) 11 1 1.09 - .92 1.00E00 1.00E00 vitamin metabolic process (GO:0006766) 44 4 4.35 - .92 1.00E00 1.00E00 folic acid-containing compound metabolic process (GO:0006760) 22 2 2.18 - .92 1.00E00 1.00E00 female meiosis I (GO:0007144) 11 1 1.09 - .92 1.00E00 1.00E00 plasma membrane repair (GO:0001778) 11 1 1.09 - .92 1.00E00 1.00E00 protein catabolic process in the vacuole (GO:0007039) 11 1 1.09 - .92 1.00E00 1.00E00 vacuolar acidification (GO:0007035) 22 2 2.18 - .92 1.00E00 1.00E00 cytoplasm organization (GO:0007028) 11 1 1.09 - .92 1.00E00 1.00E00 membrane hyperpolarization (GO:0060081) 11 1 1.09 - .92 1.00E00 1.00E00 regulation of T-helper 2 cell cytokine production (GO:2000551) 11 1 1.09 - .92 1.00E00 1.00E00 cysteine metabolic process (GO:0006534) 11 1 1.09 - .92 1.00E00 1.00E00 positive regulation of amino acid transport (GO:0051957) 22 2 2.18 - .92 1.00E00 1.00E00 sulfation (GO:0051923) 11 1 1.09 - .92 1.00E00 1.00E00 positive regulation of cellular amine metabolic process (GO:0033240) 11 1 1.09 - .92 1.00E00 1.00E00 tRNA 5'-leader removal (GO:0001682) 11 1 1.09 - .92 1.00E00 1.00E00 peptidyl-proline hydroxylation to 4-hydroxy-L-proline (GO:0018401) 11 1 1.09 - .92 1.00E00 1.00E00 positive regulation of glutamate secretion (GO:0014049) 11 1 1.09 - .92 1.00E00 1.00E00 cellular response to superoxide (GO:0071451) 11 1 1.09 - .92 1.00E00 1.00E00 cellular response to oxygen radical (GO:0071450) 11 1 1.09 - .92 1.00E00 1.00E00 development of secondary sexual characteristics (GO:0045136) 11 1 1.09 - .92 1.00E00 1.00E00 cartilage condensation (GO:0001502) 11 1 1.09 - .92 1.00E00 1.00E00 actin nucleation (GO:0045010) 22 2 2.18 - .92 1.00E00 1.00E00 regulation of myoblast proliferation (GO:2000291) 11 1 1.09 - .92 1.00E00 1.00E00 negative regulation of phosphoprotein phosphatase activity (GO:0032515) 22 2 2.18 - .92 1.00E00 1.00E00 DNA replication initiation (GO:0006270) 22 2 2.18 - .92 1.00E00 1.00E00 positive regulation of cell aging (GO:0090343) 11 1 1.09 - .92 1.00E00 1.00E00 regulation of brown fat cell differentiation (GO:0090335) 22 2 2.18 - .92 1.00E00 1.00E00 negative regulation of translation, ncRNA-mediated (GO:0040033) 11 1 1.09 - .92 1.00E00 1.00E00 positive regulation of mitochondrial calcium ion concentration (GO:0051561) 11 1 1.09 - .92 1.00E00 1.00E00 negative regulation by host of viral transcription (GO:0043922) 11 1 1.09 - .92 1.00E00 1.00E00 positive regulation of synaptic plasticity (GO:0031915) 11 1 1.09 - .92 1.00E00 1.00E00 negative regulation of double-strand break repair via homologous recombination (GO:2000042) 11 1 1.09 - .92 1.00E00 1.00E00 negative regulation of hormone biosynthetic process (GO:0032353) 11 1 1.09 - .92 1.00E00 1.00E00 negative regulation of voltage-gated calcium channel activity (GO:1901386) 11 1 1.09 - .92 1.00E00 1.00E00 regulation of ventricular cardiac muscle cell action potential (GO:0098911) 11 1 1.09 - .92 1.00E00 1.00E00 endoplasmic reticulum membrane organization (GO:0090158) 11 1 1.09 - .92 1.00E00 1.00E00 meiotic chromosome separation (GO:0051307) 22 2 2.18 - .92 1.00E00 1.00E00 regulation of fat cell proliferation (GO:0070344) 11 1 1.09 - .92 1.00E00 1.00E00 presynaptic modulation of chemical synaptic transmission (GO:0099171) 11 1 1.09 - .92 1.00E00 1.00E00 calcium import into the mitochondrion (GO:0036444) 11 1 1.09 - .92 1.00E00 1.00E00 regulation of postsynaptic density assembly (GO:0099151) 11 1 1.09 - .92 1.00E00 1.00E00 smooth muscle cell differentiation (GO:0051145) 44 4 4.35 - .92 1.00E00 1.00E00 lymphocyte apoptotic process (GO:0070227) 22 2 2.18 - .92 1.00E00 1.00E00 modification of postsynaptic structure (GO:0099010) 11 1 1.09 - .92 1.00E00 1.00E00 positive regulation of mRNA 3'-end processing (GO:0031442) 11 1 1.09 - .92 1.00E00 1.00E00 regulation of lipoprotein lipase activity (GO:0051004) 11 1 1.09 - .92 1.00E00 1.00E00 positive regulation of defense response to bacterium (GO:1900426) 11 1 1.09 - .92 1.00E00 1.00E00 carnitine metabolic process (GO:0009437) 11 1 1.09 - .92 1.00E00 1.00E00 toxin metabolic process (GO:0009404) 11 1 1.09 - .92 1.00E00 1.00E00 somatic stem cell division (GO:0048103) 11 1 1.09 - .92 1.00E00 1.00E00 oligosaccharide biosynthetic process (GO:0009312) 11 1 1.09 - .92 1.00E00 1.00E00 mitochondrial ATP synthesis coupled proton transport (GO:0042776) 11 1 1.09 - .92 1.00E00 1.00E00 regulation of guanyl-nucleotide exchange factor activity (GO:1905097) 11 1 1.09 - .92 1.00E00 1.00E00 regulation of metallopeptidase activity (GO:1905048) 11 1 1.09 - .92 1.00E00 1.00E00 glycolipid biosynthetic process (GO:0009247) 55 5 5.44 - .92 1.00E00 1.00E00 SNARE complex assembly (GO:0035493) 11 1 1.09 - .92 1.00E00 1.00E00 retinal metabolic process (GO:0042574) 11 1 1.09 - .92 1.00E00 1.00E00 negative regulation of cellular response to hypoxia (GO:1900038) 11 1 1.09 - .92 1.00E00 1.00E00 monosaccharide transmembrane transport (GO:0015749) 22 2 2.18 - .92 1.00E00 1.00E00 positive regulation of T cell chemotaxis (GO:0010820) 11 1 1.09 - .92 1.00E00 1.00E00 negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804) 11 1 1.09 - .92 1.00E00 1.00E00 miRNA mediated inhibition of translation (GO:0035278) 11 1 1.09 - .92 1.00E00 1.00E00 protein autophosphorylation (GO:0046777) 176 16 17.40 - .92 8.99E-01 1.00E00 synaptic vesicle localization (GO:0097479) 44 4 4.35 - .92 1.00E00 1.00E00 regulation of gene silencing by miRNA (GO:0060964) 44 4 4.35 - .92 1.00E00 1.00E00 gamma-delta T cell activation (GO:0046629) 11 1 1.09 - .92 1.00E00 1.00E00 lipid glycosylation (GO:0030259) 11 1 1.09 - .92 1.00E00 1.00E00 programmed cell death involved in cell development (GO:0010623) 11 1 1.09 - .92 1.00E00 1.00E00 axonal transport of mitochondrion (GO:0019896) 11 1 1.09 - .92 1.00E00 1.00E00 regulation of DNA catabolic process (GO:1903624) 11 1 1.09 - .92 1.00E00 1.00E00 regulation of Rac protein signal transduction (GO:0035020) 22 2 2.18 - .92 1.00E00 1.00E00 piRNA metabolic process (GO:0034587) 11 1 1.09 - .92 1.00E00 1.00E00 myotube differentiation (GO:0014902) 55 5 5.44 - .92 1.00E00 1.00E00 nicotinamide nucleotide metabolic process (GO:0046496) 22 2 2.18 - .92 1.00E00 1.00E00 glycosphingolipid catabolic process (GO:0046479) 11 1 1.09 - .92 1.00E00 1.00E00 regulation of skeletal muscle satellite cell proliferation (GO:0014842) 11 1 1.09 - .92 1.00E00 1.00E00 microvillus assembly (GO:0030033) 11 1 1.09 - .92 1.00E00 1.00E00 muscle cell migration (GO:0014812) 22 2 2.18 - .92 1.00E00 1.00E00 regulation of translation, ncRNA-mediated (GO:0045974) 11 1 1.09 - .92 1.00E00 1.00E00 negative regulation of fatty acid metabolic process (GO:0045922) 22 2 2.18 - .92 1.00E00 1.00E00 negative regulation of protein polyubiquitination (GO:1902915) 11 1 1.09 - .92 1.00E00 1.00E00 eyelid development in camera-type eye (GO:0061029) 11 1 1.09 - .92 1.00E00 1.00E00 adult heart development (GO:0007512) 11 1 1.09 - .92 1.00E00 1.00E00 pyrimidine-containing compound transmembrane transport (GO:0072531) 11 1 1.09 - .92 1.00E00 1.00E00 positive regulation of cell cycle G1/S phase transition (GO:1902808) 44 4 4.35 - .92 1.00E00 1.00E00 organophosphate metabolic process (GO:0019637) 639 58 63.18 - .92 5.88E-01 1.00E00 phosphate-containing compound metabolic process (GO:0006796) 1393 126 137.73 - .91 3.46E-01 1.00E00 telencephalon development (GO:0021537) 188 17 18.59 - .91 8.07E-01 1.00E00 respiratory tube development (GO:0030323) 177 16 17.50 - .91 8.99E-01 1.00E00 positive regulation of biosynthetic process (GO:0009891) 1571 142 155.33 - .91 3.04E-01 1.00E00 regionalization (GO:0003002) 244 22 24.12 - .91 7.47E-01 1.00E00 phosphorylation (GO:0016310) 733 66 72.47 - .91 4.86E-01 1.00E00 transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169) 300 27 29.66 - .91 6.97E-01 1.00E00 respiratory system development (GO:0060541) 200 18 19.77 - .91 8.12E-01 1.00E00 mitochondrial transport (GO:0006839) 178 16 17.60 - .91 8.01E-01 1.00E00 ear development (GO:0043583) 178 16 17.60 - .91 8.01E-01 1.00E00 polyol metabolic process (GO:0019751) 89 8 8.80 - .91 1.00E00 1.00E00 catabolic process (GO:0009056) 1491 134 147.42 - .91 2.73E-01 1.00E00 regulation of cellular catabolic process (GO:0031329) 679 61 67.13 - .91 5.11E-01 1.00E00 phosphorus metabolic process (GO:0006793) 1415 127 139.90 - .91 2.82E-01 1.00E00 plasma membrane bounded cell projection morphogenesis (GO:0120039) 390 35 38.56 - .91 6.67E-01 1.00E00 regulation of dendrite morphogenesis (GO:0048814) 78 7 7.71 - .91 1.00E00 1.00E00 tissue migration (GO:0090130) 78 7 7.71 - .91 1.00E00 1.00E00 protein polymerization (GO:0051258) 78 7 7.71 - .91 1.00E00 1.00E00 cellular component organization (GO:0016043) 4316 387 426.73 - .91 2.95E-02 4.44E-01 cellular response to ketone (GO:1901655) 67 6 6.62 - .91 1.00E00 1.00E00 stress-activated MAPK cascade (GO:0051403) 67 6 6.62 - .91 1.00E00 1.00E00 positive regulation of JUN kinase activity (GO:0043507) 67 6 6.62 - .91 1.00E00 1.00E00 glycoprotein biosynthetic process (GO:0009101) 201 18 19.87 - .91 8.12E-01 1.00E00 nucleobase-containing small molecule biosynthetic process (GO:0034404) 67 6 6.62 - .91 1.00E00 1.00E00 positive regulation of developmental growth (GO:0048639) 179 16 17.70 - .90 8.01E-01 1.00E00 regulation of cellular metabolic process (GO:0031323) 4724 422 467.07 - .90 1.57E-02 2.91E-01 negative regulation of G1/S transition of mitotic cell cycle (GO:2000134) 56 5 5.54 - .90 1.00E00 1.00E00 regulation of G1/S transition of mitotic cell cycle (GO:2000045) 112 10 11.07 - .90 8.74E-01 1.00E00 regulation of morphogenesis of an epithelium (GO:1905330) 56 5 5.54 - .90 1.00E00 1.00E00 visual learning (GO:0008542) 56 5 5.54 - .90 1.00E00 1.00E00 keratinocyte differentiation (GO:0030216) 56 5 5.54 - .90 1.00E00 1.00E00 synaptic vesicle cycle (GO:0099504) 101 9 9.99 - .90 1.00E00 1.00E00 rhythmic process (GO:0048511) 202 18 19.97 - .90 8.12E-01 1.00E00 hindbrain morphogenesis (GO:0021575) 45 4 4.45 - .90 1.00E00 1.00E00 regulation of muscle tissue development (GO:1901861) 45 4 4.45 - .90 1.00E00 1.00E00 cytokinesis (GO:0000910) 90 8 8.90 - .90 1.00E00 1.00E00 mitochondrion localization (GO:0051646) 45 4 4.45 - .90 1.00E00 1.00E00 positive regulation of neural precursor cell proliferation (GO:2000179) 45 4 4.45 - .90 1.00E00 1.00E00 negative regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043124) 45 4 4.45 - .90 1.00E00 1.00E00 female pregnancy (GO:0007565) 90 8 8.90 - .90 1.00E00 1.00E00 blood vessel diameter maintenance (GO:0097746) 124 11 12.26 - .90 8.80E-01 1.00E00 regulation of tube diameter (GO:0035296) 124 11 12.26 - .90 8.80E-01 1.00E00 regulation of tube size (GO:0035150) 124 11 12.26 - .90 8.80E-01 1.00E00 positive regulation of cellular biosynthetic process (GO:0031328) 1534 136 151.67 - .90 2.06E-01 1.00E00 viral life cycle (GO:0019058) 79 7 7.81 - .90 1.00E00 1.00E00 odontogenesis (GO:0042476) 79 7 7.81 - .90 1.00E00 1.00E00 positive regulation of cytoskeleton organization (GO:0051495) 181 16 17.90 - .89 8.02E-01 1.00E00 cerebellar cortex morphogenesis (GO:0021696) 34 3 3.36 - .89 1.00E00 1.00E00 regulation of receptor internalization (GO:0002090) 68 6 6.72 - .89 1.00E00 1.00E00 regulation of isotype switching (GO:0045191) 34 3 3.36 - .89 1.00E00 1.00E00 protein targeting to ER (GO:0045047) 34 3 3.36 - .89 1.00E00 1.00E00 DNA duplex unwinding (GO:0032508) 34 3 3.36 - .89 1.00E00 1.00E00 cytokinetic process (GO:0032506) 34 3 3.36 - .89 1.00E00 1.00E00 negative regulation of actin filament bundle assembly (GO:0032232) 34 3 3.36 - .89 1.00E00 1.00E00 establishment of spindle orientation (GO:0051294) 34 3 3.36 - .89 1.00E00 1.00E00 axis specification (GO:0009798) 68 6 6.72 - .89 1.00E00 1.00E00 tight junction assembly (GO:0120192) 34 3 3.36 - .89 1.00E00 1.00E00 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:0000288) 34 3 3.36 - .89 1.00E00 1.00E00 protein localization to lysosome (GO:0061462) 34 3 3.36 - .89 1.00E00 1.00E00 epithelial tube morphogenesis (GO:0060562) 306 27 30.25 - .89 6.29E-01 1.00E00 negative regulation of nitrogen compound metabolic process (GO:0051172) 1916 169 189.44 - .89 1.30E-01 9.73E-01 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090092) 193 17 19.08 - .89 7.17E-01 1.00E00 protein glycosylation (GO:0006486) 159 14 15.72 - .89 7.89E-01 1.00E00 macromolecule glycosylation (GO:0043413) 159 14 15.72 - .89 7.89E-01 1.00E00 hindbrain development (GO:0030902) 125 11 12.36 - .89 8.80E-01 1.00E00 gene silencing (GO:0016458) 125 11 12.36 - .89 8.80E-01 1.00E00 female sex differentiation (GO:0046660) 91 8 9.00 - .89 8.61E-01 1.00E00 negative regulation of axonogenesis (GO:0050771) 57 5 5.64 - .89 1.00E00 1.00E00 head development (GO:0060322) 548 48 54.18 - .89 4.66E-01 1.00E00 kidney development (GO:0001822) 240 21 23.73 - .88 6.63E-01 1.00E00 regulation of developmental growth (GO:0048638) 320 28 31.64 - .88 6.35E-01 1.00E00 regulation of cellular amide metabolic process (GO:0034248) 389 34 38.46 - .88 5.47E-01 1.00E00 sterol metabolic process (GO:0016125) 103 9 10.18 - .88 8.69E-01 1.00E00 cartilage development (GO:0051216) 126 11 12.46 - .88 8.80E-01 1.00E00 cellular component organization or biogenesis (GO:0071840) 4502 392 445.12 - .88 3.75E-03 1.02E-01 proteolysis (GO:0006508) 908 79 89.78 - .88 2.76E-01 1.00E00 organelle disassembly (GO:1903008) 69 6 6.82 - .88 1.00E00 1.00E00 renal tubule development (GO:0061326) 69 6 6.82 - .88 1.00E00 1.00E00 carbohydrate transmembrane transport (GO:0034219) 23 2 2.27 - .88 1.00E00 1.00E00 regulation of keratinocyte differentiation (GO:0045616) 23 2 2.27 - .88 1.00E00 1.00E00 regulation of receptor localization to synapse (GO:1902683) 23 2 2.27 - .88 1.00E00 1.00E00 Golgi to plasma membrane transport (GO:0006893) 46 4 4.55 - .88 1.00E00 1.00E00 positive regulation of proteolysis involved in cellular protein catabolic process (GO:1903052) 115 10 11.37 - .88 8.75E-01 1.00E00 positive regulation of cell junction assembly (GO:1901890) 92 8 9.10 - .88 8.61E-01 1.00E00 chondrocyte development (GO:0002063) 23 2 2.27 - .88 1.00E00 1.00E00 negative regulation of reproductive process (GO:2000242) 46 4 4.55 - .88 1.00E00 1.00E00 cellular senescence (GO:0090398) 23 2 2.27 - .88 1.00E00 1.00E00 negative regulation of cell aging (GO:0090344) 23 2 2.27 - .88 1.00E00 1.00E00 energy reserve metabolic process (GO:0006112) 46 4 4.55 - .88 1.00E00 1.00E00 positive regulation of protein autophosphorylation (GO:0031954) 23 2 2.27 - .88 1.00E00 1.00E00 regulation of stress fiber assembly (GO:0051492) 92 8 9.10 - .88 8.61E-01 1.00E00 vesicle-mediated transport between endosomal compartments (GO:0098927) 23 2 2.27 - .88 1.00E00 1.00E00 regulation of spindle assembly (GO:0090169) 23 2 2.27 - .88 1.00E00 1.00E00 cytoplasmic sequestering of protein (GO:0051220) 23 2 2.27 - .88 1.00E00 1.00E00 negative regulation of calcium ion transmembrane transporter activity (GO:1901020) 23 2 2.27 - .88 1.00E00 1.00E00 heterochromatin assembly (GO:0031507) 23 2 2.27 - .88 1.00E00 1.00E00 negative regulation of receptor signaling pathway via STAT (GO:1904893) 23 2 2.27 - .88 1.00E00 1.00E00 establishment of protein localization to plasma membrane (GO:0061951) 46 4 4.55 - .88 1.00E00 1.00E00 vascular endothelial growth factor receptor signaling pathway (GO:0048010) 23 2 2.27 - .88 1.00E00 1.00E00 ribonucleoside metabolic process (GO:0009119) 23 2 2.27 - .88 1.00E00 1.00E00 pore complex assembly (GO:0046931) 23 2 2.27 - .88 1.00E00 1.00E00 C4-dicarboxylate transport (GO:0015740) 23 2 2.27 - .88 1.00E00 1.00E00 negative regulation of nucleocytoplasmic transport (GO:0046823) 23 2 2.27 - .88 1.00E00 1.00E00 negative regulation of steroid biosynthetic process (GO:0010894) 23 2 2.27 - .88 1.00E00 1.00E00 positive regulation of cholesterol efflux (GO:0010875) 23 2 2.27 - .88 1.00E00 1.00E00 regulation of production of miRNAs involved in gene silencing by miRNA (GO:1903798) 23 2 2.27 - .88 1.00E00 1.00E00 negative regulation of Rho protein signal transduction (GO:0035024) 23 2 2.27 - .88 1.00E00 1.00E00 negative regulation of receptor signaling pathway via JAK-STAT (GO:0046426) 23 2 2.27 - .88 1.00E00 1.00E00 negative regulation of heart contraction (GO:0045822) 23 2 2.27 - .88 1.00E00 1.00E00 atrioventricular valve development (GO:0003171) 23 2 2.27 - .88 1.00E00 1.00E00 heterocycle catabolic process (GO:0046700) 242 21 23.93 - .88 6.64E-01 1.00E00 neuron projection development (GO:0031175) 577 50 57.05 - .88 3.93E-01 1.00E00 positive regulation of Wnt signaling pathway (GO:0030177) 127 11 12.56 - .88 7.66E-01 1.00E00 regulation of transforming growth factor beta receptor signaling pathway (GO:0017015) 104 9 10.28 - .88 8.69E-01 1.00E00 female gonad development (GO:0008585) 81 7 8.01 - .87 8.53E-01 1.00E00 positive regulation of macromolecule biosynthetic process (GO:0010557) 1447 125 143.07 - .87 1.38E-01 1.00E00 organonitrogen compound biosynthetic process (GO:1901566) 961 83 95.02 - .87 2.40E-01 1.00E00 positive regulation of growth (GO:0045927) 255 22 25.21 - .87 5.97E-01 1.00E00 organic substance metabolic process (GO:0071704) 5877 507 581.07 - .87 1.50E-04 7.27E-03 negative regulation of intracellular transport (GO:0032387) 58 5 5.73 - .87 1.00E00 1.00E00 visual behavior (GO:0007632) 58 5 5.73 - .87 1.00E00 1.00E00 regulation of Wnt signaling pathway (GO:0030111) 267 23 26.40 - .87 6.04E-01 1.00E00 regulation of primary metabolic process (GO:0080090) 4552 392 450.06 - .87 1.58E-03 5.19E-02 neuron differentiation (GO:0030182) 825 71 81.57 - .87 2.79E-01 1.00E00 positive regulation of cell growth (GO:0030307) 163 14 16.12 - .87 6.93E-01 1.00E00 inner ear receptor cell stereocilium organization (GO:0060122) 35 3 3.46 - .87 1.00E00 1.00E00 positive regulation of amine transport (GO:0051954) 35 3 3.46 - .87 1.00E00 1.00E00 glandular epithelial cell differentiation (GO:0002067) 35 3 3.46 - .87 1.00E00 1.00E00 negative regulation of organelle assembly (GO:1902116) 35 3 3.46 - .87 1.00E00 1.00E00 protein depolymerization (GO:0051261) 35 3 3.46 - .87 1.00E00 1.00E00 dicarboxylic acid metabolic process (GO:0043648) 70 6 6.92 - .87 1.00E00 1.00E00 positive regulation of bone mineralization (GO:0030501) 35 3 3.46 - .87 1.00E00 1.00E00 positive regulation of pathway-restricted SMAD protein phosphorylation (GO:0010862) 35 3 3.46 - .87 1.00E00 1.00E00 positive regulation of epithelial cell apoptotic process (GO:1904037) 35 3 3.46 - .87 1.00E00 1.00E00 cellular response to toxic substance (GO:0097237) 35 3 3.46 - .87 1.00E00 1.00E00 steroid metabolic process (GO:0008202) 175 15 17.30 - .87 7.02E-01 1.00E00 pH reduction (GO:0045851) 35 3 3.46 - .87 1.00E00 1.00E00 cellular response to dopamine (GO:1903351) 35 3 3.46 - .87 1.00E00 1.00E00 response to dopamine (GO:1903350) 35 3 3.46 - .87 1.00E00 1.00E00 regulation of actin filament bundle assembly (GO:0032231) 105 9 10.38 - .87 8.69E-01 1.00E00 embryonic organ development (GO:0048568) 385 33 38.07 - .87 4.88E-01 1.00E00 metabolic process (GO:0008152) 6234 534 616.36 - .87 3.01E-05 1.90E-03 post-Golgi vesicle-mediated transport (GO:0006892) 82 7 8.11 - .86 8.53E-01 1.00E00 maintenance of location in cell (GO:0051651) 82 7 8.11 - .86 8.53E-01 1.00E00 nucleoside triphosphate metabolic process (GO:0009141) 82 7 8.11 - .86 8.53E-01 1.00E00 organic cyclic compound catabolic process (GO:1901361) 270 23 26.70 - .86 5.38E-01 1.00E00 regulation of posttranscriptional gene silencing (GO:0060147) 47 4 4.65 - .86 1.00E00 1.00E00 mitotic G2/M transition checkpoint (GO:0044818) 47 4 4.65 - .86 1.00E00 1.00E00 regulation of nitrogen compound metabolic process (GO:0051171) 4413 375 436.32 - .86 7.55E-04 2.89E-02 positive regulation of transcription by RNA polymerase II (GO:0045944) 977 83 96.60 - .86 1.83E-01 1.00E00 developmental growth involved in morphogenesis (GO:0060560) 106 9 10.48 - .86 8.69E-01 1.00E00 nitrogen compound transport (GO:0071705) 1308 111 129.32 - .86 1.09E-01 9.07E-01 macroautophagy (GO:0016236) 118 10 11.67 - .86 7.57E-01 1.00E00 regulation of cell size (GO:0008361) 177 15 17.50 - .86 7.03E-01 1.00E00 epithelium development (GO:0060429) 815 69 80.58 - .86 2.26E-01 1.00E00 cell-cell junction organization (GO:0045216) 130 11 12.85 - .86 7.67E-01 1.00E00 positive regulation of protein modification by small protein conjugation or removal (GO:1903322) 130 11 12.85 - .86 7.67E-01 1.00E00 protein targeting to membrane (GO:0006612) 71 6 7.02 - .85 8.43E-01 1.00E00 regulation of BMP signaling pathway (GO:0030510) 71 6 7.02 - .85 8.43E-01 1.00E00 cellular response to unfolded protein (GO:0034620) 71 6 7.02 - .85 8.43E-01 1.00E00 axo-dendritic transport (GO:0008088) 71 6 7.02 - .85 8.43E-01 1.00E00 positive regulation of nucleic acid-templated transcription (GO:1903508) 1231 104 121.71 - .85 1.10E-01 9.15E-01 positive regulation of transcription, DNA-templated (GO:0045893) 1231 104 121.71 - .85 1.10E-01 9.15E-01 positive regulation of RNA biosynthetic process (GO:1902680) 1232 104 121.81 - .85 1.10E-01 9.16E-01 inner ear morphogenesis (GO:0042472) 83 7 8.21 - .85 8.53E-01 1.00E00 neuron development (GO:0048666) 700 59 69.21 - .85 2.42E-01 1.00E00 organic substance catabolic process (GO:1901575) 1246 105 123.19 - .85 1.01E-01 8.80E-01 locomotory behavior (GO:0007626) 178 15 17.60 - .85 7.03E-01 1.00E00 response to ketone (GO:1901654) 95 8 9.39 - .85 8.62E-01 1.00E00 skeletal system morphogenesis (GO:0048705) 190 16 18.79 - .85 6.24E-01 1.00E00 regulation of gene expression, epigenetic (GO:0040029) 107 9 10.58 - .85 7.46E-01 1.00E00 regulation of cellular response to transforming growth factor beta stimulus (GO:1903844) 107 9 10.58 - .85 7.46E-01 1.00E00 regulation of canonical Wnt signaling pathway (GO:0060828) 214 18 21.16 - .85 5.65E-01 1.00E00 embryonic organ morphogenesis (GO:0048562) 238 20 23.53 - .85 5.83E-01 1.00E00 dendrite development (GO:0016358) 119 10 11.77 - .85 7.57E-01 1.00E00 sensory perception (GO:0007600) 430 36 42.51 - .85 3.66E-01 1.00E00 vesicle organization (GO:0016050) 227 19 22.44 - .85 5.74E-01 1.00E00 negative regulation of biosynthetic process (GO:0009890) 1327 111 131.20 - .85 8.21E-02 8.15E-01 protein localization to membrane (GO:0072657) 407 34 40.24 - .84 3.98E-01 1.00E00 sensory organ development (GO:0007423) 455 38 44.99 - .84 3.38E-01 1.00E00 positive regulation of epidermal growth factor-activated receptor activity (GO:0045741) 12 1 1.19 - .84 1.00E00 1.00E00 lung epithelial cell differentiation (GO:0060487) 24 2 2.37 - .84 1.00E00 1.00E00 atrial septum morphogenesis (GO:0060413) 12 1 1.19 - .84 1.00E00 1.00E00 regulation of toll-like receptor 2 signaling pathway (GO:0034135) 12 1 1.19 - .84 1.00E00 1.00E00 positive regulation of keratinocyte differentiation (GO:0045618) 12 1 1.19 - .84 1.00E00 1.00E00 pyridine nucleotide metabolic process (GO:0019362) 24 2 2.37 - .84 1.00E00 1.00E00 microtubule anchoring at microtubule organizing center (GO:0072393) 12 1 1.19 - .84 1.00E00 1.00E00 positive regulation of catecholamine secretion (GO:0033605) 12 1 1.19 - .84 1.00E00 1.00E00 cranial nerve morphogenesis (GO:0021602) 24 2 2.37 - .84 1.00E00 1.00E00 intrinsic apoptotic signaling pathway by p53 class mediator (GO:0072332) 48 4 4.75 - .84 1.00E00 1.00E00 regulation of Fc receptor mediated stimulatory signaling pathway (GO:0060368) 12 1 1.19 - .84 1.00E00 1.00E00 methylguanosine-cap decapping (GO:0110156) 12 1 1.19 - .84 1.00E00 1.00E00 neurotransmitter transport (GO:0006836) 96 8 9.49 - .84 8.63E-01 1.00E00 chloride transport (GO:0006821) 60 5 5.93 - .84 1.00E00 1.00E00 regulation of gamma-delta T cell differentiation (GO:0045586) 12 1 1.19 - .84 1.00E00 1.00E00 positive regulation of cation channel activity (GO:2001259) 60 5 5.93 - .84 1.00E00 1.00E00 suckling behavior (GO:0001967) 12 1 1.19 - .84 1.00E00 1.00E00 metanephric nephron morphogenesis (GO:0072273) 12 1 1.19 - .84 1.00E00 1.00E00 regulation of feeding behavior (GO:0060259) 24 2 2.37 - .84 1.00E00 1.00E00 negative regulation of stem cell differentiation (GO:2000737) 24 2 2.37 - .84 1.00E00 1.00E00 regulation of organelle transport along microtubule (GO:1902513) 12 1 1.19 - .84 1.00E00 1.00E00 positive regulation of phospholipid transport (GO:2001140) 12 1 1.19 - .84 1.00E00 1.00E00 meiosis II (GO:0007135) 12 1 1.19 - .84 1.00E00 1.00E00 angiogenesis involved in wound healing (GO:0060055) 12 1 1.19 - .84 1.00E00 1.00E00 polyamine biosynthetic process (GO:0006596) 12 1 1.19 - .84 1.00E00 1.00E00 synaptic transmission, GABAergic (GO:0051932) 12 1 1.19 - .84 1.00E00 1.00E00 C-terminal protein amino acid modification (GO:0018410) 12 1 1.19 - .84 1.00E00 1.00E00 regulation of mitochondrial membrane potential (GO:0051881) 72 6 7.12 - .84 8.43E-01 1.00E00 regulation of production of small RNA involved in gene silencing by RNA (GO:0070920) 24 2 2.37 - .84 1.00E00 1.00E00 retinoid metabolic process (GO:0001523) 36 3 3.56 - .84 1.00E00 1.00E00 positive regulation of viral release from host cell (GO:1902188) 12 1 1.19 - .84 1.00E00 1.00E00 cellular response to exogenous dsRNA (GO:0071360) 12 1 1.19 - .84 1.00E00 1.00E00 regulation of nuclear division (GO:0051783) 120 10 11.86 - .84 7.58E-01 1.00E00 positive regulation of viral genome replication (GO:0045070) 24 2 2.37 - .84 1.00E00 1.00E00 positive regulation of killing of cells of other organism (GO:0051712) 12 1 1.19 - .84 1.00E00 1.00E00 regulation of protein exit from endoplasmic reticulum (GO:0070861) 24 2 2.37 - .84 1.00E00 1.00E00 heterochromatin organization (GO:0070828) 36 3 3.56 - .84 1.00E00 1.00E00 microvillus organization (GO:0032528) 12 1 1.19 - .84 1.00E00 1.00E00 negative regulation of cilium assembly (GO:1902018) 12 1 1.19 - .84 1.00E00 1.00E00 negative regulation of amyloid fibril formation (GO:1905907) 12 1 1.19 - .84 1.00E00 1.00E00 vesicle fusion to plasma membrane (GO:0099500) 12 1 1.19 - .84 1.00E00 1.00E00 lysosome localization (GO:0032418) 48 4 4.75 - .84 1.00E00 1.00E00 regulation of meiotic nuclear division (GO:0040020) 24 2 2.37 - .84 1.00E00 1.00E00 negative regulation of synapse organization (GO:1905809) 12 1 1.19 - .84 1.00E00 1.00E00 regulation of non-canonical Wnt signaling pathway (GO:2000050) 24 2 2.37 - .84 1.00E00 1.00E00 cellular response to fibroblast growth factor stimulus (GO:0044344) 48 4 4.75 - .84 1.00E00 1.00E00 regulation of stem cell division (GO:2000035) 12 1 1.19 - .84 1.00E00 1.00E00 negative regulation of hormone metabolic process (GO:0032351) 12 1 1.19 - .84 1.00E00 1.00E00 negative regulation of protein localization to cell surface (GO:2000009) 12 1 1.19 - .84 1.00E00 1.00E00 N-acetylglucosamine metabolic process (GO:0006044) 12 1 1.19 - .84 1.00E00 1.00E00 cell-cell recognition (GO:0009988) 48 4 4.75 - .84 1.00E00 1.00E00 cellular nitrogen compound catabolic process (GO:0044270) 240 20 23.73 - .84 5.13E-01 1.00E00 positive regulation of synaptic transmission, GABAergic (GO:0032230) 12 1 1.19 - .84 1.00E00 1.00E00 positive regulation of protein localization to endosome (GO:1905668) 12 1 1.19 - .84 1.00E00 1.00E00 bone growth (GO:0098868) 24 2 2.37 - .84 1.00E00 1.00E00 negative regulation of catabolic process (GO:0009895) 276 23 27.29 - .84 4.76E-01 1.00E00 positive regulation of oxidoreductase activity (GO:0051353) 48 4 4.75 - .84 1.00E00 1.00E00 protein transport along microtubule (GO:0098840) 12 1 1.19 - .84 1.00E00 1.00E00 positive regulation of release of sequestered calcium ion into cytosol (GO:0051281) 36 3 3.56 - .84 1.00E00 1.00E00 bone cell development (GO:0098751) 24 2 2.37 - .84 1.00E00 1.00E00 cell aggregation (GO:0098743) 12 1 1.19 - .84 1.00E00 1.00E00 cellular protein complex disassembly (GO:0043624) 48 4 4.75 - .84 1.00E00 1.00E00 positive regulation of heat generation (GO:0031652) 12 1 1.19 - .84 1.00E00 1.00E00 regulation of protein stability (GO:0031647) 276 23 27.29 - .84 4.76E-01 1.00E00 synaptic vesicle fusion to presynaptic active zone membrane (GO:0031629) 12 1 1.19 - .84 1.00E00 1.00E00 tight junction organization (GO:0120193) 36 3 3.56 - .84 1.00E00 1.00E00 positive regulation of vacuole organization (GO:0044090) 12 1 1.19 - .84 1.00E00 1.00E00 regulation of lipoprotein metabolic process (GO:0050746) 12 1 1.19 - .84 1.00E00 1.00E00 microtubule-based protein transport (GO:0099118) 12 1 1.19 - .84 1.00E00 1.00E00 positive regulation of isotype switching to IgG isotypes (GO:0048304) 12 1 1.19 - .84 1.00E00 1.00E00 cellular response to increased oxygen levels (GO:0036295) 12 1 1.19 - .84 1.00E00 1.00E00 negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948) 12 1 1.19 - .84 1.00E00 1.00E00 negative regulation of cardiocyte differentiation (GO:1905208) 12 1 1.19 - .84 1.00E00 1.00E00 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059) 36 3 3.56 - .84 1.00E00 1.00E00 cortical cytoskeleton organization (GO:0030865) 60 5 5.93 - .84 1.00E00 1.00E00 epithelial cell differentiation (GO:0030855) 384 32 37.97 - .84 3.86E-01 1.00E00 meiosis II cell cycle process (GO:0061983) 12 1 1.19 - .84 1.00E00 1.00E00 mRNA transcription by RNA polymerase II (GO:0042789) 12 1 1.19 - .84 1.00E00 1.00E00 regulation of sulfur metabolic process (GO:0042762) 12 1 1.19 - .84 1.00E00 1.00E00 very long-chain fatty acid biosynthetic process (GO:0042761) 12 1 1.19 - .84 1.00E00 1.00E00 fucosylation (GO:0036065) 12 1 1.19 - .84 1.00E00 1.00E00 regulation of vitamin metabolic process (GO:0030656) 12 1 1.19 - .84 1.00E00 1.00E00 vitamin biosynthetic process (GO:0009110) 12 1 1.19 - .84 1.00E00 1.00E00 mitochondrial protein processing (GO:0034982) 12 1 1.19 - .84 1.00E00 1.00E00 regulation of protein K63-linked ubiquitination (GO:1900044) 12 1 1.19 - .84 1.00E00 1.00E00 cytoskeleton-dependent cytokinesis (GO:0061640) 84 7 8.31 - .84 8.54E-01 1.00E00 male gonad development (GO:0008584) 96 8 9.49 - .84 8.63E-01 1.00E00 synaptic vesicle maturation (GO:0016188) 12 1 1.19 - .84 1.00E00 1.00E00 positive regulation of myotube differentiation (GO:0010831) 12 1 1.19 - .84 1.00E00 1.00E00 negative regulation of centrosome duplication (GO:0010826) 12 1 1.19 - .84 1.00E00 1.00E00 regulation of T cell chemotaxis (GO:0010819) 12 1 1.19 - .84 1.00E00 1.00E00 terpenoid biosynthetic process (GO:0016114) 12 1 1.19 - .84 1.00E00 1.00E00 ganglion development (GO:0061548) 12 1 1.19 - .84 1.00E00 1.00E00 extraembryonic membrane development (GO:1903867) 12 1 1.19 - .84 1.00E00 1.00E00 vasodilation (GO:0042311) 36 3 3.56 - .84 1.00E00 1.00E00 genitalia morphogenesis (GO:0035112) 12 1 1.19 - .84 1.00E00 1.00E00 regulation of gene silencing by RNA (GO:0060966) 48 4 4.75 - .84 1.00E00 1.00E00 cardiac vascular smooth muscle cell differentiation (GO:0060947) 12 1 1.19 - .84 1.00E00 1.00E00 regulation of gamma-delta T cell activation (GO:0046643) 12 1 1.19 - .84 1.00E00 1.00E00 negative regulation of centrosome cycle (GO:0046606) 12 1 1.19 - .84 1.00E00 1.00E00 regulation of retrograde protein transport, ER to cytosol (GO:1904152) 12 1 1.19 - .84 1.00E00 1.00E00 endosome to lysosome transport (GO:0008333) 48 4 4.75 - .84 1.00E00 1.00E00 regulation of mitochondrial fusion (GO:0010635) 12 1 1.19 - .84 1.00E00 1.00E00 positive regulation of cytoplasmic transport (GO:1903651) 12 1 1.19 - .84 1.00E00 1.00E00 development of primary female sexual characteristics (GO:0046545) 84 7 8.31 - .84 8.54E-01 1.00E00 negative regulation of cyclin-dependent protein kinase activity (GO:1904030) 24 2 2.37 - .84 1.00E00 1.00E00 tooth mineralization (GO:0034505) 12 1 1.19 - .84 1.00E00 1.00E00 response to fluid shear stress (GO:0034405) 24 2 2.37 - .84 1.00E00 1.00E00 regulation of embryonic development (GO:0045995) 48 4 4.75 - .84 1.00E00 1.00E00 exit from mitosis (GO:0010458) 12 1 1.19 - .84 1.00E00 1.00E00 positive regulation of calcium ion-dependent exocytosis (GO:0045956) 12 1 1.19 - .84 1.00E00 1.00E00 negative regulation of steroid metabolic process (GO:0045939) 24 2 2.37 - .84 1.00E00 1.00E00 negative regulation of vasoconstriction (GO:0045906) 12 1 1.19 - .84 1.00E00 1.00E00 positive regulation of amyloid precursor protein catabolic process (GO:1902993) 24 2 2.37 - .84 1.00E00 1.00E00 cardiac atrium morphogenesis (GO:0003209) 24 2 2.37 - .84 1.00E00 1.00E00 positive regulation of meiotic nuclear division (GO:0045836) 12 1 1.19 - .84 1.00E00 1.00E00 positive regulation of cartilage development (GO:0061036) 24 2 2.37 - .84 1.00E00 1.00E00 intestinal epithelial cell development (GO:0060576) 12 1 1.19 - .84 1.00E00 1.00E00 ATP metabolic process (GO:0046034) 156 13 15.42 - .84 6.84E-01 1.00E00 protein metabolic process (GO:0019538) 2966 247 293.25 - .84 3.44E-03 9.51E-02 positive regulation of RNA metabolic process (GO:0051254) 1350 112 133.48 - .84 6.17E-02 6.97E-01 regulation of intracellular protein transport (GO:0033157) 205 17 20.27 - .84 5.55E-01 1.00E00 visual system development (GO:0150063) 302 25 29.86 - .84 4.35E-01 1.00E00 sensory perception of mechanical stimulus (GO:0050954) 145 12 14.34 - .84 6.74E-01 1.00E00 lipid modification (GO:0030258) 145 12 14.34 - .84 6.74E-01 1.00E00 animal organ morphogenesis (GO:0009887) 786 65 77.71 - .84 1.75E-01 9.82E-01 aromatic compound catabolic process (GO:0019439) 254 21 25.11 - .84 5.23E-01 1.00E00 cellular catabolic process (GO:0044248) 1320 109 130.51 - .84 5.90E-02 6.80E-01 macromolecule localization (GO:0033036) 2011 166 198.83 - .83 1.57E-02 2.92E-01 development of primary male sexual characteristics (GO:0046546) 97 8 9.59 - .83 7.34E-01 1.00E00 postsynapse organization (GO:0099173) 85 7 8.40 - .83 8.54E-01 1.00E00 regulation of multicellular organism growth (GO:0040014) 73 6 7.22 - .83 8.44E-01 1.00E00 stress-activated protein kinase signaling cascade (GO:0031098) 73 6 7.22 - .83 8.44E-01 1.00E00 tube formation (GO:0035148) 146 12 14.44 - .83 6.74E-01 1.00E00 regulation of protein localization to nucleus (GO:1900180) 134 11 13.25 - .83 6.62E-01 1.00E00 positive regulation of cellular protein catabolic process (GO:1903364) 134 11 13.25 - .83 6.62E-01 1.00E00 regulation of biosynthetic process (GO:0009889) 3245 266 320.84 - .83 7.66E-04 2.91E-02 sensory system development (GO:0048880) 305 25 30.16 - .83 4.36E-01 1.00E00 morphogenesis of an epithelium (GO:0002009) 415 34 41.03 - .83 3.16E-01 1.00E00 establishment of organelle localization (GO:0051656) 306 25 30.25 - .83 4.37E-01 1.00E00 negative regulation of translation (GO:0017148) 147 12 14.53 - .83 6.75E-01 1.00E00 central nervous system neuron differentiation (GO:0021953) 147 12 14.53 - .83 6.75E-01 1.00E00 regulation of cell cycle G2/M phase transition (GO:1902749) 98 8 9.69 - .83 7.34E-01 1.00E00 mitochondrial membrane organization (GO:0007006) 98 8 9.69 - .83 7.34E-01 1.00E00 pattern specification process (GO:0007389) 319 26 31.54 - .82 3.92E-01 1.00E00 regulation of cell division (GO:0051302) 135 11 13.35 - .82 6.62E-01 1.00E00 tissue morphogenesis (GO:0048729) 491 40 48.55 - .82 2.48E-01 1.00E00 autophagy (GO:0006914) 221 18 21.85 - .82 4.95E-01 1.00E00 process utilizing autophagic mechanism (GO:0061919) 221 18 21.85 - .82 4.95E-01 1.00E00 phosphatidylinositol biosynthetic process (GO:0006661) 86 7 8.50 - .82 8.55E-01 1.00E00 negative regulation of cell cycle (GO:0045786) 295 24 29.17 - .82 4.28E-01 1.00E00 aromatic compound biosynthetic process (GO:0019438) 616 50 60.90 - .82 1.89E-01 1.00E00 reproductive process (GO:0022414) 1035 84 102.33 - .82 7.39E-02 7.50E-01 reproduction (GO:0000003) 1036 84 102.43 - .82 7.40E-02 7.50E-01 face morphogenesis (GO:0060325) 37 3 3.66 - .82 1.00E00 1.00E00 tRNA aminoacylation for protein translation (GO:0006418) 37 3 3.66 - .82 1.00E00 1.00E00 anterior/posterior axis specification (GO:0009948) 37 3 3.66 - .82 1.00E00 1.00E00 vesicle-mediated transport in synapse (GO:0099003) 111 9 10.97 - .82 7.48E-01 1.00E00 regulation of protein import (GO:1904589) 74 6 7.32 - .82 8.44E-01 1.00E00 ribonucleoside monophosphate metabolic process (GO:0009161) 37 3 3.66 - .82 1.00E00 1.00E00 positive regulation of G1/S transition of mitotic cell cycle (GO:1900087) 37 3 3.66 - .82 1.00E00 1.00E00 cyclic-nucleotide-mediated signaling (GO:0019935) 37 3 3.66 - .82 1.00E00 1.00E00 central nervous system neuron axonogenesis (GO:0021955) 37 3 3.66 - .82 1.00E00 1.00E00 regulation of microtubule-based movement (GO:0060632) 37 3 3.66 - .82 1.00E00 1.00E00 establishment of protein localization to endoplasmic reticulum (GO:0072599) 37 3 3.66 - .82 1.00E00 1.00E00 organonitrogen compound catabolic process (GO:1901565) 827 67 81.77 - .82 1.18E-01 9.54E-01 developmental process involved in reproduction (GO:0003006) 729 59 72.08 - .82 1.42E-01 1.00E00 regulation of mitotic nuclear division (GO:0007088) 99 8 9.79 - .82 7.34E-01 1.00E00 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090101) 99 8 9.79 - .82 7.34E-01 1.00E00 sex differentiation (GO:0007548) 198 16 19.58 - .82 5.47E-01 1.00E00 gonad development (GO:0008406) 161 13 15.92 - .82 5.93E-01 1.00E00 positive regulation of intrinsic apoptotic signaling pathway (GO:2001244) 62 5 6.13 - .82 8.31E-01 1.00E00 regulation of synaptic vesicle exocytosis (GO:2000300) 62 5 6.13 - .82 8.31E-01 1.00E00 positive regulation of muscle cell differentiation (GO:0051149) 62 5 6.13 - .82 8.31E-01 1.00E00 cellular response to alcohol (GO:0097306) 62 5 6.13 - .82 8.31E-01 1.00E00 epidermis development (GO:0008544) 186 15 18.39 - .82 5.35E-01 1.00E00 positive regulation of nucleobase-containing compound metabolic process (GO:0045935) 1502 121 148.50 - .81 2.22E-02 3.69E-01 organophosphate biosynthetic process (GO:0090407) 360 29 35.59 - .81 3.24E-01 1.00E00 cell projection organization (GO:0030030) 970 78 95.91 - .81 7.39E-02 7.51E-01 regulation of dendrite development (GO:0050773) 112 9 11.07 - .81 6.35E-01 1.00E00 cellular component assembly (GO:0022607) 1780 143 175.99 - .81 1.08E-02 2.33E-01 regulation of organelle organization (GO:0033043) 1073 86 106.09 - .81 5.50E-02 6.40E-01 central nervous system neuron development (GO:0021954) 75 6 7.42 - .81 8.45E-01 1.00E00 lung cell differentiation (GO:0060479) 25 2 2.47 - .81 1.00E00 1.00E00 negative regulation of osteoclast differentiation (GO:0045671) 25 2 2.47 - .81 1.00E00 1.00E00 cerebellar cortex formation (GO:0021697) 25 2 2.47 - .81 1.00E00 1.00E00 antigen processing and presentation of endogenous peptide antigen (GO:0002483) 25 2 2.47 - .81 1.00E00 1.00E00 response to fibroblast growth factor (GO:0071774) 50 4 4.94 - .81 1.00E00 1.00E00 NADH metabolic process (GO:0006734) 25 2 2.47 - .81 1.00E00 1.00E00 maternal placenta development (GO:0001893) 25 2 2.47 - .81 1.00E00 1.00E00 positive regulation of monooxygenase activity (GO:0032770) 25 2 2.47 - .81 1.00E00 1.00E00 negative regulation of type I interferon production (GO:0032480) 25 2 2.47 - .81 1.00E00 1.00E00 positive regulation of cytokinesis (GO:0032467) 25 2 2.47 - .81 1.00E00 1.00E00 intracellular lipid transport (GO:0032365) 25 2 2.47 - .81 1.00E00 1.00E00 negative regulation of receptor-mediated endocytosis (GO:0048261) 25 2 2.47 - .81 1.00E00 1.00E00 T cell costimulation (GO:0031295) 25 2 2.47 - .81 1.00E00 1.00E00 hindlimb morphogenesis (GO:0035137) 25 2 2.47 - .81 1.00E00 1.00E00 antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) 25 2 2.47 - .81 1.00E00 1.00E00 regulation of cellular biosynthetic process (GO:0031326) 3180 254 314.41 - .81 1.91E-04 9.10E-03 organic substance biosynthetic process (GO:1901576) 1830 146 180.93 - .81 7.23E-03 1.69E-01 plasma membrane bounded cell projection organization (GO:0120036) 916 73 90.57 - .81 6.66E-02 7.37E-01 male sex differentiation (GO:0046661) 113 9 11.17 - .81 6.35E-01 1.00E00 regulation of signaling receptor activity (GO:0010469) 113 9 11.17 - .81 6.35E-01 1.00E00 regulation of mitotic cell cycle phase transition (GO:1901990) 264 21 26.10 - .80 4.03E-01 1.00E00 spinal cord development (GO:0021510) 63 5 6.23 - .80 8.32E-01 1.00E00 inner ear receptor cell differentiation (GO:0060113) 63 5 6.23 - .80 8.32E-01 1.00E00 negative regulation of RNA catabolic process (GO:1902369) 63 5 6.23 - .80 8.32E-01 1.00E00 phosphatidylinositol-mediated signaling (GO:0048015) 63 5 6.23 - .80 8.32E-01 1.00E00 negative regulation of cellular biosynthetic process (GO:0031327) 1288 102 127.35 - .80 2.40E-02 3.91E-01 biosynthetic process (GO:0009058) 1882 149 186.08 - .80 4.79E-03 1.22E-01 positive regulation of peptidyl-lysine acetylation (GO:2000758) 38 3 3.76 - .80 1.00E00 1.00E00 mesenchyme morphogenesis (GO:0072132) 38 3 3.76 - .80 1.00E00 1.00E00 regulation of protein acetylation (GO:1901983) 76 6 7.51 - .80 8.46E-01 1.00E00 DNA geometric change (GO:0032392) 38 3 3.76 - .80 1.00E00 1.00E00 glucose metabolic process (GO:0006006) 76 6 7.51 - .80 8.46E-01 1.00E00 inositol phosphate metabolic process (GO:0043647) 38 3 3.76 - .80 1.00E00 1.00E00 diterpenoid metabolic process (GO:0016101) 38 3 3.76 - .80 1.00E00 1.00E00 regulation of membrane depolarization (GO:0003254) 38 3 3.76 - .80 1.00E00 1.00E00 development of primary sexual characteristics (GO:0045137) 165 13 16.31 - .80 5.10E-01 1.00E00 regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032434) 127 10 12.56 - .80 6.51E-01 1.00E00 carbohydrate derivative biosynthetic process (GO:1901137) 395 31 39.05 - .79 2.30E-01 1.00E00 cerebellar cortex development (GO:0021695) 51 4 5.04 - .79 8.16E-01 1.00E00 nephron tubule morphogenesis (GO:0072078) 51 4 5.04 - .79 8.16E-01 1.00E00 cellular component maintenance (GO:0043954) 51 4 5.04 - .79 8.16E-01 1.00E00 RNA stabilization (GO:0043489) 51 4 5.04 - .79 8.16E-01 1.00E00 negative regulation of chromatin organization (GO:1905268) 51 4 5.04 - .79 8.16E-01 1.00E00 regulation of mitotic cell cycle (GO:0007346) 409 32 40.44 - .79 2.37E-01 1.00E00 embryonic morphogenesis (GO:0048598) 473 37 46.77 - .79 1.81E-01 1.00E00 regulation of protein catabolic process (GO:0042176) 358 28 35.40 - .79 2.43E-01 1.00E00 macromolecule metabolic process (GO:0043170) 4578 358 452.63 - .79 2.07E-07 2.59E-05 protein targeting (GO:0006605) 205 16 20.27 - .79 4.08E-01 1.00E00 nitrogen compound metabolic process (GO:0006807) 4997 390 494.06 - .79 2.18E-08 3.25E-06 regulation of smoothened signaling pathway (GO:0008589) 77 6 7.61 - .79 7.02E-01 1.00E00 cellular response to stress (GO:0033554) 1311 102 129.62 - .79 1.49E-02 2.81E-01 synaptic signaling (GO:0099536) 271 21 26.79 - .78 3.03E-01 1.00E00 mitotic cell cycle phase transition (GO:0044772) 142 11 14.04 - .78 5.69E-01 1.00E00 negative regulation of cellular catabolic process (GO:0031330) 220 17 21.75 - .78 3.62E-01 1.00E00 eye development (GO:0001654) 299 23 29.56 - .78 2.79E-01 1.00E00 regulation of G2/M transition of mitotic cell cycle (GO:0010389) 91 7 9.00 - .78 7.22E-01 1.00E00 nuclear envelope organization (GO:0006998) 39 3 3.86 - .78 1.00E00 1.00E00 endochondral bone morphogenesis (GO:0060350) 52 4 5.14 - .78 8.16E-01 1.00E00 cell volume homeostasis (GO:0006884) 26 2 2.57 - .78 1.00E00 1.00E00 GTP metabolic process (GO:0046039) 26 2 2.57 - .78 1.00E00 1.00E00 regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) 13 1 1.29 - .78 1.00E00 1.00E00 regulation of store-operated calcium entry (GO:2001256) 13 1 1.29 - .78 1.00E00 1.00E00 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241) 13 1 1.29 - .78 1.00E00 1.00E00 regulation of phospholipid transport (GO:2001138) 13 1 1.29 - .78 1.00E00 1.00E00 blastocyst formation (GO:0001825) 52 4 5.14 - .78 8.16E-01 1.00E00 ectodermal placode development (GO:0071696) 13 1 1.29 - .78 1.00E00 1.00E00 positive regulation of endothelial cell chemotaxis (GO:2001028) 13 1 1.29 - .78 1.00E00 1.00E00 nephron epithelium morphogenesis (GO:0072088) 52 4 5.14 - .78 8.16E-01 1.00E00 somitogenesis (GO:0001756) 52 4 5.14 - .78 8.16E-01 1.00E00 nephron morphogenesis (GO:0072028) 52 4 5.14 - .78 8.16E-01 1.00E00 negative regulation of mRNA catabolic process (GO:1902373) 52 4 5.14 - .78 8.16E-01 1.00E00 cardiac muscle cell proliferation (GO:0060038) 13 1 1.29 - .78 1.00E00 1.00E00 multi-organism cellular process (GO:0044764) 13 1 1.29 - .78 1.00E00 1.00E00 regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253) 26 2 2.57 - .78 1.00E00 1.00E00 signal peptide processing (GO:0006465) 13 1 1.29 - .78 1.00E00 1.00E00 negative regulation of receptor internalization (GO:0002091) 13 1 1.29 - .78 1.00E00 1.00E00 positive regulation of focal adhesion assembly (GO:0051894) 26 2 2.57 - .78 1.00E00 1.00E00 regulation of histone ubiquitination (GO:0033182) 13 1 1.29 - .78 1.00E00 1.00E00 histone H3-K9 demethylation (GO:0033169) 13 1 1.29 - .78 1.00E00 1.00E00 regulation of membrane permeability (GO:0090559) 65 5 6.43 - .78 8.33E-01 1.00E00 positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110) 13 1 1.29 - .78 1.00E00 1.00E00 cellular response to epidermal growth factor stimulus (GO:0071364) 39 3 3.86 - .78 1.00E00 1.00E00 positive regulation of protein exit from endoplasmic reticulum (GO:0070863) 13 1 1.29 - .78 1.00E00 1.00E00 endosome transport via multivesicular body sorting pathway (GO:0032509) 26 2 2.57 - .78 1.00E00 1.00E00 Rab protein signal transduction (GO:0032482) 13 1 1.29 - .78 1.00E00 1.00E00 histone H3-K9 methylation (GO:0051567) 13 1 1.29 - .78 1.00E00 1.00E00 DNA catabolic process, endonucleolytic (GO:0000737) 13 1 1.29 - .78 1.00E00 1.00E00 myoblast migration (GO:0051451) 13 1 1.29 - .78 1.00E00 1.00E00 Golgi ribbon formation (GO:0090161) 13 1 1.29 - .78 1.00E00 1.00E00 calcium ion transmembrane transport (GO:0070588) 117 9 11.57 - .78 6.38E-01 1.00E00 secretory granule localization (GO:0032252) 13 1 1.29 - .78 1.00E00 1.00E00 regulation of protein localization to endosome (GO:1905666) 13 1 1.29 - .78 1.00E00 1.00E00 cellular oxidant detoxification (GO:0098869) 13 1 1.29 - .78 1.00E00 1.00E00 regulation of protein deubiquitination (GO:0090085) 13 1 1.29 - .78 1.00E00 1.00E00 mRNA cleavage involved in mRNA processing (GO:0098787) 13 1 1.29 - .78 1.00E00 1.00E00 tRNA 5'-end processing (GO:0099116) 13 1 1.29 - .78 1.00E00 1.00E00 positive regulation of smooth muscle cell differentiation (GO:0051152) 13 1 1.29 - .78 1.00E00 1.00E00 regulation of retinoic acid receptor signaling pathway (GO:0048385) 13 1 1.29 - .78 1.00E00 1.00E00 endoplasmic reticulum unfolded protein response (GO:0030968) 52 4 5.14 - .78 8.16E-01 1.00E00 polysaccharide catabolic process (GO:0000272) 13 1 1.29 - .78 1.00E00 1.00E00 regulation of cardiocyte differentiation (GO:1905207) 26 2 2.57 - .78 1.00E00 1.00E00 regulation of vascular associated smooth muscle cell migration (GO:1904752) 26 2 2.57 - .78 1.00E00 1.00E00 histone phosphorylation (GO:0016572) 26 2 2.57 - .78 1.00E00 1.00E00 retinal ganglion cell axon guidance (GO:0031290) 13 1 1.29 - .78 1.00E00 1.00E00 locomotory exploration behavior (GO:0035641) 13 1 1.29 - .78 1.00E00 1.00E00 chromatin-mediated maintenance of transcription (GO:0048096) 13 1 1.29 - .78 1.00E00 1.00E00 regulation of microtubule polymerization (GO:0031113) 52 4 5.14 - .78 8.16E-01 1.00E00 regulation of cell fate specification (GO:0042659) 13 1 1.29 - .78 1.00E00 1.00E00 fatty acid homeostasis (GO:0055089) 13 1 1.29 - .78 1.00E00 1.00E00 DNA methylation involved in gamete generation (GO:0043046) 13 1 1.29 - .78 1.00E00 1.00E00 pre-miRNA processing (GO:0031054) 13 1 1.29 - .78 1.00E00 1.00E00 male genitalia development (GO:0030539) 13 1 1.29 - .78 1.00E00 1.00E00 negative regulation of axon extension (GO:0030517) 39 3 3.86 - .78 1.00E00 1.00E00 regulation of phosphatase activity (GO:0010921) 78 6 7.71 - .78 7.03E-01 1.00E00 carbohydrate phosphorylation (GO:0046835) 13 1 1.29 - .78 1.00E00 1.00E00 negative regulation of TORC1 signaling (GO:1904262) 13 1 1.29 - .78 1.00E00 1.00E00 heart formation (GO:0060914) 13 1 1.29 - .78 1.00E00 1.00E00 ncRNA catabolic process (GO:0034661) 26 2 2.57 - .78 1.00E00 1.00E00 chondroitin sulfate biosynthetic process (GO:0030206) 13 1 1.29 - .78 1.00E00 1.00E00 spongiotrophoblast layer development (GO:0060712) 13 1 1.29 - .78 1.00E00 1.00E00 regulation of skeletal muscle cell proliferation (GO:0014857) 13 1 1.29 - .78 1.00E00 1.00E00 regulation of mesenchymal cell proliferation (GO:0010464) 39 3 3.86 - .78 1.00E00 1.00E00 copulation (GO:0007620) 13 1 1.29 - .78 1.00E00 1.00E00 mitotic DNA replication (GO:1902969) 13 1 1.29 - .78 1.00E00 1.00E00 cardiac left ventricle morphogenesis (GO:0003214) 13 1 1.29 - .78 1.00E00 1.00E00 forebrain regionalization (GO:0021871) 13 1 1.29 - .78 1.00E00 1.00E00 regulation of protein folding (GO:1903332) 13 1 1.29 - .78 1.00E00 1.00E00 cellular protein modification process (GO:0006464) 2021 155 199.82 - .78 8.28E-04 3.12E-02 protein modification process (GO:0036211) 2021 155 199.82 - .78 8.28E-04 3.11E-02 protein stabilization (GO:0050821) 170 13 16.81 - .77 4.36E-01 1.00E00 regulation of macromolecule biosynthetic process (GO:0010556) 3037 232 300.27 - .77 1.60E-05 1.11E-03 peptidyl-amino acid modification (GO:0018193) 668 51 66.05 - .77 7.16E-02 7.39E-01 negative regulation of transcription by RNA polymerase II (GO:0000122) 748 57 73.96 - .77 5.02E-02 6.05E-01 activation of GTPase activity (GO:0090630) 92 7 9.10 - .77 6.00E-01 1.00E00 protein-containing complex assembly (GO:0065003) 907 69 89.68 - .77 2.84E-02 4.41E-01 regulation of cellular macromolecule biosynthetic process (GO:2000112) 3005 228 297.11 - .77 1.08E-05 8.11E-04 regulation of cell cycle (GO:0051726) 858 65 84.83 - .77 3.28E-02 4.76E-01 inositol lipid-mediated signaling (GO:0048017) 66 5 6.53 - .77 8.34E-01 1.00E00 mechanoreceptor differentiation (GO:0042490) 66 5 6.53 - .77 8.34E-01 1.00E00 organelle localization (GO:0051640) 436 33 43.11 - .77 1.41E-01 1.00E00 primary metabolic process (GO:0044238) 5393 408 533.21 - .77 3.58E-11 7.06E-09 regulation of dephosphorylation (GO:0035303) 119 9 11.77 - .76 5.35E-01 1.00E00 localization within membrane (GO:0051668) 463 35 45.78 - .76 1.30E-01 9.73E-01 protein localization (GO:0008104) 1720 130 170.06 - .76 1.39E-03 4.69E-02 hexose metabolic process (GO:0019318) 106 8 10.48 - .76 6.21E-01 1.00E00 JNK cascade (GO:0007254) 53 4 5.24 - .76 8.16E-01 1.00E00 protein targeting to mitochondrion (GO:0006626) 53 4 5.24 - .76 8.16E-01 1.00E00 regulation of RNA biosynthetic process (GO:2001141) 2584 195 255.48 - .76 4.45E-05 2.69E-03 regulation of transcription, DNA-templated (GO:0006355) 2578 194 254.89 - .76 3.74E-05 2.30E-03 regulation of nucleic acid-templated transcription (GO:1903506) 2582 194 255.29 - .76 3.24E-05 2.04E-03 positive regulation of cellular protein localization (GO:1903829) 253 19 25.01 - .76 2.85E-01 1.00E00 cellular component biogenesis (GO:0044085) 1998 150 197.55 - .76 3.63E-04 1.56E-02 mammary gland morphogenesis (GO:0060443) 40 3 3.95 - .76 1.00E00 1.00E00 roof of mouth development (GO:0060021) 80 6 7.91 - .76 7.04E-01 1.00E00 synaptic vesicle transport (GO:0048489) 40 3 3.95 - .76 1.00E00 1.00E00 regulation of JUN kinase activity (GO:0043506) 80 6 7.91 - .76 7.04E-01 1.00E00 tRNA aminoacylation (GO:0043039) 40 3 3.95 - .76 1.00E00 1.00E00 negative regulation of BMP signaling pathway (GO:0030514) 40 3 3.95 - .76 1.00E00 1.00E00 regulation of cell cycle phase transition (GO:1901987) 334 25 33.02 - .76 1.92E-01 1.00E00 cellular biosynthetic process (GO:0044249) 1777 133 175.69 - .76 7.62E-04 2.90E-02 protein-containing complex subunit organization (GO:0043933) 1030 77 101.84 - .76 1.42E-02 2.71E-01 cellular metabolic process (GO:0044237) 5583 417 552.00 - .76 1.37E-12 3.47E-10 cellular process involved in reproduction in multicellular organism (GO:0022412) 308 23 30.45 - .76 2.07E-01 1.00E00 oogenesis (GO:0048477) 67 5 6.62 - .75 6.82E-01 1.00E00 regulation of defense response to virus (GO:0050688) 67 5 6.62 - .75 6.82E-01 1.00E00 kidney morphogenesis (GO:0060993) 67 5 6.62 - .75 6.82E-01 1.00E00 cell surface receptor signaling pathway involved in cell-cell signaling (GO:1905114) 228 17 22.54 - .75 3.10E-01 1.00E00 organic cyclic compound biosynthetic process (GO:1901362) 698 52 69.01 - .75 4.27E-02 5.59E-01 Notch signaling pathway (GO:0007219) 94 7 9.29 - .75 6.00E-01 1.00E00 cytoskeleton-dependent intracellular transport (GO:0030705) 175 13 17.30 - .75 3.70E-01 1.00E00 cellular localization (GO:0051641) 1967 146 194.48 - .75 2.40E-04 1.12E-02 regulation of translation (GO:0006417) 337 25 33.32 - .75 1.92E-01 1.00E00 face development (GO:0060324) 54 4 5.34 - .75 8.17E-01 1.00E00 positive regulation of animal organ morphogenesis (GO:0110110) 27 2 2.67 - .75 1.00E00 1.00E00 regulation of epidermal growth factor-activated receptor activity (GO:0007176) 27 2 2.67 - .75 1.00E00 1.00E00 cellular response to gamma radiation (GO:0071480) 27 2 2.67 - .75 1.00E00 1.00E00 midbrain development (GO:0030901) 27 2 2.67 - .75 1.00E00 1.00E00 lymphocyte costimulation (GO:0031294) 27 2 2.67 - .75 1.00E00 1.00E00 regulation of cyclase activity (GO:0031279) 27 2 2.67 - .75 1.00E00 1.00E00 pteridine-containing compound metabolic process (GO:0042558) 27 2 2.67 - .75 1.00E00 1.00E00 regulation of mitochondrial membrane permeability (GO:0046902) 54 4 5.34 - .75 8.17E-01 1.00E00 positive regulation of transforming growth factor beta receptor signaling pathway (GO:0030511) 27 2 2.67 - .75 1.00E00 1.00E00 positive regulation of cellular response to transforming growth factor beta stimulus (GO:1903846) 27 2 2.67 - .75 1.00E00 1.00E00 negative regulation of gene silencing (GO:0060969) 27 2 2.67 - .75 1.00E00 1.00E00 myotube cell development (GO:0014904) 27 2 2.67 - .75 1.00E00 1.00E00 regulation of cell fate commitment (GO:0010453) 27 2 2.67 - .75 1.00E00 1.00E00 establishment of localization in cell (GO:0051649) 1369 101 135.35 - .75 2.57E-03 7.56E-02 regulation of RNA metabolic process (GO:0051252) 2838 209 280.60 - .74 2.90E-06 2.51E-04 regulation of nucleobase-containing compound metabolic process (GO:0019219) 3058 225 302.35 - .74 8.52E-07 8.62E-05 RNA destabilization (GO:0050779) 68 5 6.72 - .74 6.82E-01 1.00E00 regulation of protein import into nucleus (GO:0042306) 68 5 6.72 - .74 6.82E-01 1.00E00 negative regulation of macromolecule biosynthetic process (GO:0010558) 1238 91 122.40 - .74 3.68E-03 1.01E-01 heterocycle biosynthetic process (GO:0018130) 613 45 60.61 - .74 5.11E-02 6.13E-01 potassium ion transport (GO:0006813) 109 8 10.78 - .74 5.17E-01 1.00E00 nucleobase-containing compound catabolic process (GO:0034655) 218 16 21.55 - .74 2.99E-01 1.00E00 negative regulation of transcription, DNA-templated (GO:0045892) 1022 75 101.05 - .74 8.66E-03 1.95E-01 positive regulation of organelle organization (GO:0010638) 532 39 52.60 - .74 7.34E-02 7.48E-01 macromolecule modification (GO:0043412) 2185 160 216.03 - .74 4.84E-05 2.88E-03 cranial nerve development (GO:0021545) 41 3 4.05 - .74 7.95E-01 1.00E00 regulation of meiotic cell cycle (GO:0051445) 41 3 4.05 - .74 7.95E-01 1.00E00 apical junction assembly (GO:0043297) 41 3 4.05 - .74 7.95E-01 1.00E00 protein secretion (GO:0009306) 82 6 8.11 - .74 5.78E-01 1.00E00 vesicle transport along microtubule (GO:0047496) 41 3 4.05 - .74 7.95E-01 1.00E00 amino acid activation (GO:0043038) 41 3 4.05 - .74 7.95E-01 1.00E00 water homeostasis (GO:0030104) 41 3 4.05 - .74 7.95E-01 1.00E00 negative regulation of RNA biosynthetic process (GO:1902679) 1026 75 101.44 - .74 7.50E-03 1.74E-01 negative regulation of nucleic acid-templated transcription (GO:1903507) 1026 75 101.44 - .74 7.50E-03 1.73E-01 nucleoside phosphate metabolic process (GO:0006753) 315 23 31.14 - .74 1.78E-01 9.94E-01 positive regulation of intracellular protein transport (GO:0090316) 137 10 13.55 - .74 4.67E-01 1.00E00 organelle fusion (GO:0048284) 96 7 9.49 - .74 6.02E-01 1.00E00 positive regulation of cell-matrix adhesion (GO:0001954) 55 4 5.44 - .74 8.18E-01 1.00E00 regulation of translational initiation (GO:0006446) 55 4 5.44 - .74 8.18E-01 1.00E00 positive regulation of protein import (GO:1904591) 55 4 5.44 - .74 8.18E-01 1.00E00 negative regulation of nucleobase-containing compound metabolic process (GO:0045934) 1212 88 119.83 - .73 2.84E-03 8.14E-02 regulation of mitochondrion organization (GO:0010821) 124 9 12.26 - .73 4.47E-01 1.00E00 negative regulation of mitotic cell cycle (GO:0045930) 193 14 19.08 - .73 3.27E-01 1.00E00 response to light stimulus (GO:0009416) 262 19 25.90 - .73 2.07E-01 1.00E00 organelle transport along microtubule (GO:0072384) 69 5 6.82 - .73 6.83E-01 1.00E00 negative regulation of mitotic cell cycle phase transition (GO:1901991) 138 10 13.64 - .73 3.89E-01 1.00E00 exocytic process (GO:0140029) 69 5 6.82 - .73 6.83E-01 1.00E00 cell cycle phase transition (GO:0044770) 152 11 15.03 - .73 4.08E-01 1.00E00 developmental cell growth (GO:0048588) 83 6 8.21 - .73 5.78E-01 1.00E00 establishment of protein localization to extracellular region (GO:0035592) 83 6 8.21 - .73 5.78E-01 1.00E00 intracellular receptor signaling pathway (GO:0030522) 83 6 8.21 - .73 5.78E-01 1.00E00 posttranscriptional regulation of gene expression (GO:0010608) 429 31 42.42 - .73 9.76E-02 8.60E-01 multi-organism reproductive process (GO:0044703) 692 50 68.42 - .73 2.56E-02 4.05E-01 multi-organism process (GO:0051704) 706 51 69.80 - .73 2.67E-02 4.20E-01 neural tube closure (GO:0001843) 97 7 9.59 - .73 4.95E-01 1.00E00 ear morphogenesis (GO:0042471) 97 7 9.59 - .73 4.95E-01 1.00E00 gastrulation (GO:0007369) 111 8 10.97 - .73 5.18E-01 1.00E00 negative regulation of cellular macromolecule biosynthetic process (GO:2000113) 1223 88 120.92 - .73 2.11E-03 6.48E-02 regulation of ubiquitin-dependent protein catabolic process (GO:2000058) 153 11 15.13 - .73 4.09E-01 1.00E00 response to radiation (GO:0009314) 362 26 35.79 - .73 1.26E-01 9.52E-01 protein transport (GO:0015031) 1021 73 100.95 - .72 4.42E-03 1.14E-01 head morphogenesis (GO:0060323) 42 3 4.15 - .72 7.95E-01 1.00E00 cerebellum morphogenesis (GO:0021587) 42 3 4.15 - .72 7.95E-01 1.00E00 regulation of T cell mediated cytotoxicity (GO:0001914) 42 3 4.15 - .72 7.95E-01 1.00E00 homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156) 70 5 6.92 - .72 6.84E-01 1.00E00 negative regulation of stress-activated MAPK cascade (GO:0032873) 42 3 4.15 - .72 7.95E-01 1.00E00 regulation of organelle assembly (GO:1902115) 182 13 17.99 - .72 3.13E-01 1.00E00 response to epidermal growth factor (GO:0070849) 42 3 4.15 - .72 7.95E-01 1.00E00 protein insertion into membrane (GO:0051205) 42 3 4.15 - .72 7.95E-01 1.00E00 negative regulation of stress-activated protein kinase signaling cascade (GO:0070303) 42 3 4.15 - .72 7.95E-01 1.00E00 positive regulation of actin filament polymerization (GO:0030838) 70 5 6.92 - .72 6.84E-01 1.00E00 nucleoside metabolic process (GO:0009116) 42 3 4.15 - .72 7.95E-01 1.00E00 hair cell differentiation (GO:0035315) 42 3 4.15 - .72 7.95E-01 1.00E00 lipid oxidation (GO:0034440) 70 5 6.92 - .72 6.84E-01 1.00E00 nicotinamide nucleotide biosynthetic process (GO:0019359) 14 1 1.38 - .72 1.00E00 1.00E00 positive regulation of SMAD protein signal transduction (GO:0060391) 14 1 1.38 - .72 1.00E00 1.00E00 tricarboxylic acid metabolic process (GO:0072350) 14 1 1.38 - .72 1.00E00 1.00E00 RNA decapping (GO:0110154) 14 1 1.38 - .72 1.00E00 1.00E00 specification of animal organ identity (GO:0010092) 14 1 1.38 - .72 1.00E00 1.00E00 regulation of systemic arterial blood pressure by hormone (GO:0001990) 28 2 2.77 - .72 1.00E00 1.00E00 regulation of stem cell differentiation (GO:2000736) 56 4 5.54 - .72 6.56E-01 1.00E00 positive regulation of collagen biosynthetic process (GO:0032967) 28 2 2.77 - .72 1.00E00 1.00E00 negative regulation of viral transcription (GO:0032897) 14 1 1.38 - .72 1.00E00 1.00E00 Sertoli cell development (GO:0060009) 14 1 1.38 - .72 1.00E00 1.00E00 regulation of transmission of nerve impulse (GO:0051969) 14 1 1.38 - .72 1.00E00 1.00E00 regulation of delayed rectifier potassium channel activity (GO:1902259) 14 1 1.38 - .72 1.00E00 1.00E00 regulation of norepinephrine secretion (GO:0014061) 14 1 1.38 - .72 1.00E00 1.00E00 epithelial cell maturation (GO:0002070) 14 1 1.38 - .72 1.00E00 1.00E00 negative regulation of signal transduction by p53 class mediator (GO:1901797) 28 2 2.77 - .72 1.00E00 1.00E00 regulation of circadian sleep/wake cycle, sleep (GO:0045187) 14 1 1.38 - .72 1.00E00 1.00E00 mitochondrial transcription (GO:0006390) 14 1 1.38 - .72 1.00E00 1.00E00 negative regulation of cell division (GO:0051782) 14 1 1.38 - .72 1.00E00 1.00E00 negative regulation of signaling receptor activity (GO:2000272) 28 2 2.77 - .72 1.00E00 1.00E00 DNA strand elongation involved in DNA replication (GO:0006271) 14 1 1.38 - .72 1.00E00 1.00E00 Golgi localization (GO:0051645) 14 1 1.38 - .72 1.00E00 1.00E00 postsynapse to nucleus signaling pathway (GO:0099527) 14 1 1.38 - .72 1.00E00 1.00E00 regulation of histone H4 acetylation (GO:0090239) 14 1 1.38 - .72 1.00E00 1.00E00 postsynaptic actin cytoskeleton organization (GO:0098974) 14 1 1.38 - .72 1.00E00 1.00E00 positive regulation of axon regeneration (GO:0048680) 14 1 1.38 - .72 1.00E00 1.00E00 axon extension (GO:0048675) 28 2 2.77 - .72 1.00E00 1.00E00 post-embryonic animal morphogenesis (GO:0009886) 14 1 1.38 - .72 1.00E00 1.00E00 engulfment of apoptotic cell (GO:0043652) 14 1 1.38 - .72 1.00E00 1.00E00 postsynaptic cytoskeleton organization (GO:0099188) 14 1 1.38 - .72 1.00E00 1.00E00 regulation of postsynaptic specialization assembly (GO:0099150) 14 1 1.38 - .72 1.00E00 1.00E00 regulation of respiratory gaseous exchange (GO:0043576) 14 1 1.38 - .72 1.00E00 1.00E00 regulation of actin nucleation (GO:0051125) 28 2 2.77 - .72 1.00E00 1.00E00 negative regulation of plasma membrane bounded cell projection assembly (GO:0120033) 28 2 2.77 - .72 1.00E00 1.00E00 response to superoxide (GO:0000303) 14 1 1.38 - .72 1.00E00 1.00E00 response to increased oxygen levels (GO:0036296) 14 1 1.38 - .72 1.00E00 1.00E00 regulation of protein ubiquitination (GO:0031396) 196 14 19.38 - .72 2.75E-01 1.00E00 behavioral response to cocaine (GO:0048148) 14 1 1.38 - .72 1.00E00 1.00E00 very long-chain fatty acid metabolic process (GO:0000038) 28 2 2.77 - .72 1.00E00 1.00E00 positive regulation of microtubule polymerization (GO:0031116) 28 2 2.77 - .72 1.00E00 1.00E00 motor behavior (GO:0061744) 14 1 1.38 - .72 1.00E00 1.00E00 ventricular cardiac muscle cell differentiation (GO:0055012) 14 1 1.38 - .72 1.00E00 1.00E00 camera-type eye development (GO:0043010) 266 19 26.30 - .72 2.09E-01 1.00E00 nucleotide metabolic process (GO:0009117) 308 22 30.45 - .72 1.45E-01 1.00E00 pteridine-containing compound biosynthetic process (GO:0042559) 14 1 1.38 - .72 1.00E00 1.00E00 negative regulation of tyrosine phosphorylation of STAT protein (GO:0042532) 14 1 1.38 - .72 1.00E00 1.00E00 regulation of lipoprotein particle clearance (GO:0010984) 14 1 1.38 - .72 1.00E00 1.00E00 negative regulation of mitochondrial membrane potential (GO:0010917) 14 1 1.38 - .72 1.00E00 1.00E00 branched-chain amino acid catabolic process (GO:0009083) 14 1 1.38 - .72 1.00E00 1.00E00 bicarbonate transport (GO:0015701) 14 1 1.38 - .72 1.00E00 1.00E00 cell-cell signaling involved in cardiac conduction (GO:0086019) 14 1 1.38 - .72 1.00E00 1.00E00 fatty acid elongation (GO:0030497) 14 1 1.38 - .72 1.00E00 1.00E00 antigen processing and presentation of endogenous antigen (GO:0019883) 28 2 2.77 - .72 1.00E00 1.00E00 regulation of cytoplasmic transport (GO:1903649) 28 2 2.77 - .72 1.00E00 1.00E00 xenobiotic catabolic process (GO:0042178) 14 1 1.38 - .72 1.00E00 1.00E00 cell fate commitment involved in formation of primary germ layer (GO:0060795) 14 1 1.38 - .72 1.00E00 1.00E00 negative regulation of androgen receptor signaling pathway (GO:0060766) 14 1 1.38 - .72 1.00E00 1.00E00 trophoblast giant cell differentiation (GO:0060707) 14 1 1.38 - .72 1.00E00 1.00E00 ruffle assembly (GO:0097178) 14 1 1.38 - .72 1.00E00 1.00E00 phasic smooth muscle contraction (GO:0014821) 14 1 1.38 - .72 1.00E00 1.00E00 positive regulation of immune response to tumor cell (GO:0002839) 14 1 1.38 - .72 1.00E00 1.00E00 positive regulation of response to tumor cell (GO:0002836) 14 1 1.38 - .72 1.00E00 1.00E00 P-body assembly (GO:0033962) 14 1 1.38 - .72 1.00E00 1.00E00 cardiac atrium development (GO:0003230) 28 2 2.77 - .72 1.00E00 1.00E00 cardiac right ventricle morphogenesis (GO:0003215) 14 1 1.38 - .72 1.00E00 1.00E00 endocardial cushion morphogenesis (GO:0003203) 28 2 2.77 - .72 1.00E00 1.00E00 tube closure (GO:0060606) 98 7 9.69 - .72 4.95E-01 1.00E00 negative regulation of alcohol biosynthetic process (GO:1902931) 14 1 1.38 - .72 1.00E00 1.00E00 glucose import (GO:0046323) 14 1 1.38 - .72 1.00E00 1.00E00 positive regulation of cell growth involved in cardiac muscle cell development (GO:0061051) 14 1 1.38 - .72 1.00E00 1.00E00 lactation (GO:0007595) 28 2 2.77 - .72 1.00E00 1.00E00 peptidyl-proline hydroxylation (GO:0019511) 14 1 1.38 - .72 1.00E00 1.00E00 pulmonary valve morphogenesis (GO:0003184) 14 1 1.38 - .72 1.00E00 1.00E00 cellular protein metabolic process (GO:0044267) 2579 184 254.99 - .72 1.39E-06 1.30E-04 macromolecule catabolic process (GO:0009057) 785 56 77.61 - .72 1.33E-02 2.60E-01 organelle organization (GO:0006996) 2837 202 280.50 - .72 2.70E-07 3.23E-05 chromatin assembly (GO:0031497) 85 6 8.40 - .71 5.80E-01 1.00E00 purine nucleotide metabolic process (GO:0006163) 241 17 23.83 - .71 1.89E-01 1.00E00 purine ribonucleotide metabolic process (GO:0009150) 227 16 22.44 - .71 2.14E-01 1.00E00 negative regulation of RNA metabolic process (GO:0051253) 1121 79 110.83 - .71 1.95E-03 6.08E-02 limbic system development (GO:0021761) 71 5 7.02 - .71 6.85E-01 1.00E00 ureteric bud development (GO:0001657) 71 5 7.02 - .71 6.85E-01 1.00E00 morphogenesis of embryonic epithelium (GO:0016331) 142 10 14.04 - .71 3.91E-01 1.00E00 response to osmotic stress (GO:0006970) 57 4 5.64 - .71 6.56E-01 1.00E00 cranial skeletal system development (GO:1904888) 57 4 5.64 - .71 6.56E-01 1.00E00 negative regulation of G2/M transition of mitotic cell cycle (GO:0010972) 57 4 5.64 - .71 6.56E-01 1.00E00 renal tubule morphogenesis (GO:0061333) 57 4 5.64 - .71 6.56E-01 1.00E00 regulation of transcription by RNA polymerase II (GO:0006357) 1940 136 191.81 - .71 1.88E-05 1.24E-03 anterior/posterior pattern specification (GO:0009952) 157 11 15.52 - .71 3.41E-01 1.00E00 determination of left/right symmetry (GO:0007368) 100 7 9.89 - .71 4.96E-01 1.00E00 sexual reproduction (GO:0019953) 616 43 60.90 - .71 2.17E-02 3.64E-01 regulation of epidermal cell differentiation (GO:0045604) 43 3 4.25 - .71 7.96E-01 1.00E00 phosphatidylinositol phosphate biosynthetic process (GO:0046854) 43 3 4.25 - .71 7.96E-01 1.00E00 inorganic anion transport (GO:0015698) 86 6 8.50 - .71 5.81E-01 1.00E00 positive regulation of DNA recombination (GO:0045911) 43 3 4.25 - .71 7.96E-01 1.00E00 neural tube formation (GO:0001841) 115 8 11.37 - .70 4.28E-01 1.00E00 regulation of protein modification by small protein conjugation or removal (GO:1903320) 230 16 22.74 - .70 2.15E-01 1.00E00 purine-containing compound metabolic process (GO:0072521) 259 18 25.61 - .70 1.68E-01 1.00E00 mesonephric tubule development (GO:0072164) 72 5 7.12 - .70 5.52E-01 1.00E00 mesonephric epithelium development (GO:0072163) 72 5 7.12 - .70 5.52E-01 1.00E00 cellular protein localization (GO:0034613) 1253 87 123.89 - .70 5.75E-04 2.33E-02 regulation of proteasomal protein catabolic process (GO:0061136) 173 12 17.10 - .70 2.99E-01 1.00E00 response to unfolded protein (GO:0006986) 101 7 9.99 - .70 4.98E-01 1.00E00 positive regulation of canonical Wnt signaling pathway (GO:0090263) 101 7 9.99 - .70 4.98E-01 1.00E00 positive regulation of protein polymerization (GO:0032273) 101 7 9.99 - .70 4.98E-01 1.00E00 negative regulation of cell cycle G2/M phase transition (GO:1902750) 58 4 5.73 - .70 6.56E-01 1.00E00 immunoglobulin production involved in immunoglobulin-mediated immune response (GO:0002381) 29 2 2.87 - .70 1.00E00 1.00E00 inner mitochondrial membrane organization (GO:0007007) 29 2 2.87 - .70 1.00E00 1.00E00 regulation of lyase activity (GO:0051339) 29 2 2.87 - .70 1.00E00 1.00E00 chromosome separation (GO:0051304) 29 2 2.87 - .70 1.00E00 1.00E00 vitamin transport (GO:0051180) 29 2 2.87 - .70 1.00E00 1.00E00 regulation of smooth muscle cell differentiation (GO:0051150) 29 2 2.87 - .70 1.00E00 1.00E00 odontogenesis of dentin-containing tooth (GO:0042475) 58 4 5.73 - .70 6.56E-01 1.00E00 synaptic transmission, glutamatergic (GO:0035249) 29 2 2.87 - .70 1.00E00 1.00E00 cell growth (GO:0016049) 87 6 8.60 - .70 4.71E-01 1.00E00 programmed necrotic cell death (GO:0097300) 29 2 2.87 - .70 1.00E00 1.00E00 cellular macromolecule localization (GO:0070727) 1263 87 124.87 - .70 4.15E-04 1.74E-02 embryo development ending in birth or egg hatching (GO:0009792) 683 47 67.53 - .70 1.18E-02 2.43E-01 chordate embryonic development (GO:0043009) 669 46 66.14 - .70 1.32E-02 2.60E-01 epithelial tube formation (GO:0072175) 131 9 12.95 - .69 3.72E-01 1.00E00 phosphatidylinositol metabolic process (GO:0046488) 131 9 12.95 - .69 3.72E-01 1.00E00 primary neural tube formation (GO:0014020) 102 7 10.08 - .69 4.99E-01 1.00E00 epidermal cell differentiation (GO:0009913) 102 7 10.08 - .69 4.99E-01 1.00E00 mesonephros development (GO:0001823) 73 5 7.22 - .69 5.52E-01 1.00E00 protein localization to mitochondrion (GO:0070585) 73 5 7.22 - .69 5.52E-01 1.00E00 establishment of cell polarity (GO:0030010) 117 8 11.57 - .69 4.30E-01 1.00E00 establishment of protein localization (GO:0045184) 1112 76 109.94 - .69 8.85E-04 3.29E-02 ribose phosphate metabolic process (GO:0019693) 249 17 24.62 - .69 1.59E-01 1.00E00 cellular amide metabolic process (GO:0043603) 601 41 59.42 - .69 1.66E-02 3.06E-01 metencephalon development (GO:0022037) 88 6 8.70 - .69 4.71E-01 1.00E00 diencephalon development (GO:0021536) 44 3 4.35 - .69 7.97E-01 1.00E00 terpenoid metabolic process (GO:0006721) 44 3 4.35 - .69 7.97E-01 1.00E00 mesonephric tubule morphogenesis (GO:0072171) 44 3 4.35 - .69 7.97E-01 1.00E00 male meiotic nuclear division (GO:0007140) 44 3 4.35 - .69 7.97E-01 1.00E00 nucleoside monophosphate metabolic process (GO:0009123) 44 3 4.35 - .69 7.97E-01 1.00E00 ureteric bud morphogenesis (GO:0060675) 44 3 4.35 - .69 7.97E-01 1.00E00 generation of precursor metabolites and energy (GO:0006091) 250 17 24.72 - .69 1.60E-01 1.00E00 neural tube development (GO:0021915) 162 11 16.02 - .69 2.84E-01 1.00E00 regulation of cell cycle process (GO:0010564) 561 38 55.47 - .69 1.97E-02 3.42E-01 cellular macromolecule metabolic process (GO:0044260) 3551 240 351.09 - .68 1.37E-11 2.90E-09 regulation of histone modification (GO:0031056) 148 10 14.63 - .68 3.26E-01 1.00E00 transport along microtubule (GO:0010970) 148 10 14.63 - .68 3.26E-01 1.00E00 in utero embryonic development (GO:0001701) 444 30 43.90 - .68 4.12E-02 5.49E-01 protein localization to extracellular region (GO:0071692) 89 6 8.80 - .68 4.71E-01 1.00E00 multicellular organism reproduction (GO:0032504) 609 41 60.21 - .68 1.41E-02 2.70E-01 embryonic limb morphogenesis (GO:0030326) 104 7 10.28 - .68 4.05E-01 1.00E00 embryonic appendage morphogenesis (GO:0035113) 104 7 10.28 - .68 4.05E-01 1.00E00 visual perception (GO:0007601) 104 7 10.28 - .68 4.05E-01 1.00E00 ribonucleotide metabolic process (GO:0009259) 239 16 23.63 - .68 1.50E-01 1.00E00 multicellular organismal reproductive process (GO:0048609) 600 40 59.32 - .67 1.11E-02 2.35E-01 retrograde transport, endosome to Golgi (GO:0042147) 75 5 7.42 - .67 5.54E-01 1.00E00 alcohol catabolic process (GO:0046164) 30 2 2.97 - .67 1.00E00 1.00E00 tolerance induction (GO:0002507) 15 1 1.48 - .67 1.00E00 1.00E00 acrosome reaction (GO:0007340) 15 1 1.48 - .67 1.00E00 1.00E00 mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) 15 1 1.48 - .67 1.00E00 1.00E00 response to testosterone (GO:0033574) 15 1 1.48 - .67 1.00E00 1.00E00 chemical synaptic transmission (GO:0007268) 225 15 22.25 - .67 1.71E-01 1.00E00 regulation of endocytic recycling (GO:2001135) 15 1 1.48 - .67 1.00E00 1.00E00 activation of adenylate cyclase activity (GO:0007190) 15 1 1.48 - .67 1.00E00 1.00E00 SRP-dependent cotranslational protein targeting to membrane (GO:0006614) 15 1 1.48 - .67 1.00E00 1.00E00 microtubule depolymerization (GO:0007019) 15 1 1.48 - .67 1.00E00 1.00E00 modulation by host of viral genome replication (GO:0044827) 15 1 1.48 - .67 1.00E00 1.00E00 positive regulation of chromosome segregation (GO:0051984) 15 1 1.48 - .67 1.00E00 1.00E00 GPI anchor biosynthetic process (GO:0006506) 30 2 2.97 - .67 1.00E00 1.00E00 signaling receptor ligand precursor processing (GO:0140448) 15 1 1.48 - .67 1.00E00 1.00E00 regulation of cAMP-dependent protein kinase activity (GO:2000479) 15 1 1.48 - .67 1.00E00 1.00E00 N-glycan processing (GO:0006491) 15 1 1.48 - .67 1.00E00 1.00E00 glycogen biosynthetic process (GO:0005978) 15 1 1.48 - .67 1.00E00 1.00E00 3'-UTR-mediated mRNA stabilization (GO:0070935) 15 1 1.48 - .67 1.00E00 1.00E00 RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502) 30 2 2.97 - .67 1.00E00 1.00E00 cellular response to estrogen stimulus (GO:0071391) 15 1 1.48 - .67 1.00E00 1.00E00 regulation of cardiac muscle cell membrane repolarization (GO:0099623) 15 1 1.48 - .67 1.00E00 1.00E00 DNA unwinding involved in DNA replication (GO:0006268) 15 1 1.48 - .67 1.00E00 1.00E00 response to electrical stimulus (GO:0051602) 15 1 1.48 - .67 1.00E00 1.00E00 regulation of cell aging (GO:0090342) 45 3 4.45 - .67 7.98E-01 1.00E00 melanosome organization (GO:0032438) 15 1 1.48 - .67 1.00E00 1.00E00 regulation of protein autophosphorylation (GO:0031952) 45 3 4.45 - .67 7.98E-01 1.00E00 regulation of postsynaptic neurotransmitter receptor activity (GO:0098962) 15 1 1.48 - .67 1.00E00 1.00E00 anterograde trans-synaptic signaling (GO:0098916) 225 15 22.25 - .67 1.71E-01 1.00E00 establishment of protein localization to membrane (GO:0090150) 180 12 17.80 - .67 2.05E-01 1.00E00 epithelial cell-cell adhesion (GO:0090136) 15 1 1.48 - .67 1.00E00 1.00E00 animal organ formation (GO:0048645) 30 2 2.97 - .67 1.00E00 1.00E00 detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) 15 1 1.48 - .67 1.00E00 1.00E00 determination of bilateral symmetry (GO:0009855) 105 7 10.38 - .67 4.06E-01 1.00E00 positive regulation of vascular endothelial cell proliferation (GO:1905564) 15 1 1.48 - .67 1.00E00 1.00E00 sympathetic nervous system development (GO:0048485) 15 1 1.48 - .67 1.00E00 1.00E00 regulation of neurotransmitter receptor localization to postsynaptic specialization membrane (GO:0098696) 15 1 1.48 - .67 1.00E00 1.00E00 positive regulation of actin nucleation (GO:0051127) 15 1 1.48 - .67 1.00E00 1.00E00 regulation of defense response to bacterium (GO:1900424) 15 1 1.48 - .67 1.00E00 1.00E00 positive regulation of cardiocyte differentiation (GO:1905209) 15 1 1.48 - .67 1.00E00 1.00E00 regulation of short-term neuronal synaptic plasticity (GO:0048172) 15 1 1.48 - .67 1.00E00 1.00E00 cellular response to platelet-derived growth factor stimulus (GO:0036120) 15 1 1.48 - .67 1.00E00 1.00E00 ovulation (GO:0030728) 15 1 1.48 - .67 1.00E00 1.00E00 DNA replication checkpoint signaling (GO:0000076) 15 1 1.48 - .67 1.00E00 1.00E00 glucan biosynthetic process (GO:0009250) 15 1 1.48 - .67 1.00E00 1.00E00 purine ribonucleotide transport (GO:0015868) 15 1 1.48 - .67 1.00E00 1.00E00 retinoic acid metabolic process (GO:0042573) 15 1 1.48 - .67 1.00E00 1.00E00 regulation of mitochondrial gene expression (GO:0062125) 30 2 2.97 - .67 1.00E00 1.00E00 histone H3-K9 modification (GO:0061647) 15 1 1.48 - .67 1.00E00 1.00E00 negative regulation of production of miRNAs involved in gene silencing by miRNA (GO:1903799) 15 1 1.48 - .67 1.00E00 1.00E00 trabecula morphogenesis (GO:0061383) 45 3 4.45 - .67 7.98E-01 1.00E00 ceramide catabolic process (GO:0046514) 15 1 1.48 - .67 1.00E00 1.00E00 miRNA metabolic process (GO:0010586) 15 1 1.48 - .67 1.00E00 1.00E00 activation of cysteine-type endopeptidase activity (GO:0097202) 15 1 1.48 - .67 1.00E00 1.00E00 positive regulation of exosomal secretion (GO:1903543) 15 1 1.48 - .67 1.00E00 1.00E00 amelogenesis (GO:0097186) 15 1 1.48 - .67 1.00E00 1.00E00 striated muscle cell proliferation (GO:0014855) 15 1 1.48 - .67 1.00E00 1.00E00 negative regulation of translational initiation (GO:0045947) 15 1 1.48 - .67 1.00E00 1.00E00 ventricular trabecula myocardium morphogenesis (GO:0003222) 15 1 1.48 - .67 1.00E00 1.00E00 sex determination (GO:0007530) 15 1 1.48 - .67 1.00E00 1.00E00 nitric oxide metabolic process (GO:0046209) 15 1 1.48 - .67 1.00E00 1.00E00 cellular macromolecule catabolic process (GO:0044265) 708 47 70.00 - .67 5.06E-03 1.27E-01 establishment or maintenance of cell polarity (GO:0007163) 181 12 17.90 - .67 2.05E-01 1.00E00 cellular nitrogen compound biosynthetic process (GO:0044271) 997 66 98.57 - .67 7.03E-04 2.76E-02 response to UV (GO:0009411) 136 9 13.45 - .67 3.06E-01 1.00E00 monosaccharide metabolic process (GO:0005996) 121 8 11.96 - .67 3.52E-01 1.00E00 sensory perception of light stimulus (GO:0050953) 106 7 10.48 - .67 4.07E-01 1.00E00 specification of symmetry (GO:0009799) 106 7 10.48 - .67 4.07E-01 1.00E00 embryo development (GO:0009790) 954 63 94.32 - .67 9.98E-04 3.61E-02 nucleobase-containing small molecule metabolic process (GO:0055086) 364 24 35.99 - .67 4.83E-02 5.93E-01 endoplasmic reticulum organization (GO:0007029) 76 5 7.51 - .67 5.56E-01 1.00E00 protein lipidation (GO:0006497) 76 5 7.51 - .67 5.56E-01 1.00E00 negative regulation of cell cycle process (GO:0010948) 228 15 22.54 - .67 1.41E-01 1.00E00 RNA catabolic process (GO:0006401) 137 9 13.55 - .66 3.07E-01 1.00E00 energy derivation by oxidation of organic compounds (GO:0015980) 183 12 18.09 - .66 2.06E-01 1.00E00 peripheral nervous system development (GO:0007422) 61 4 6.03 - .66 6.61E-01 1.00E00 protein localization to endoplasmic reticulum (GO:0070972) 61 4 6.03 - .66 6.61E-01 1.00E00 apoptotic mitochondrial changes (GO:0008637) 61 4 6.03 - .66 6.61E-01 1.00E00 regulation of gene silencing (GO:0060968) 61 4 6.03 - .66 6.61E-01 1.00E00 intracellular transport (GO:0046907) 1084 71 107.18 - .66 2.78E-04 1.26E-02 positive regulation of cellular amide metabolic process (GO:0034250) 153 10 15.13 - .66 2.69E-01 1.00E00 protein catabolic process (GO:0030163) 597 39 59.03 - .66 8.77E-03 1.96E-01 cytosolic transport (GO:0016482) 123 8 12.16 - .66 2.85E-01 1.00E00 meiotic chromosome segregation (GO:0045132) 77 5 7.61 - .66 4.42E-01 1.00E00 vesicle targeting (GO:0006903) 31 2 3.07 - .65 7.65E-01 1.00E00 activation of JUN kinase activity (GO:0007257) 31 2 3.07 - .65 7.65E-01 1.00E00 regulation of mitotic spindle organization (GO:0060236) 31 2 3.07 - .65 7.65E-01 1.00E00 GPI anchor metabolic process (GO:0006505) 31 2 3.07 - .65 7.65E-01 1.00E00 regulation of renal system process (GO:0098801) 31 2 3.07 - .65 7.65E-01 1.00E00 oocyte development (GO:0048599) 31 2 3.07 - .65 7.65E-01 1.00E00 response to topologically incorrect protein (GO:0035966) 124 8 12.26 - .65 2.85E-01 1.00E00 response to exogenous dsRNA (GO:0043330) 31 2 3.07 - .65 7.65E-01 1.00E00 positive regulation of microtubule polymerization or depolymerization (GO:0031112) 31 2 3.07 - .65 7.65E-01 1.00E00 limb morphogenesis (GO:0035108) 124 8 12.26 - .65 2.85E-01 1.00E00 appendage morphogenesis (GO:0035107) 124 8 12.26 - .65 2.85E-01 1.00E00 heart trabecula morphogenesis (GO:0061384) 31 2 3.07 - .65 7.65E-01 1.00E00 mating (GO:0007618) 31 2 3.07 - .65 7.65E-01 1.00E00 potassium ion transmembrane transport (GO:0071805) 93 6 9.20 - .65 3.80E-01 1.00E00 cellular response to topologically incorrect protein (GO:0035967) 93 6 9.20 - .65 3.80E-01 1.00E00 regulation of proteolysis involved in cellular protein catabolic process (GO:1903050) 202 13 19.97 - .65 1.49E-01 1.00E00 neuron migration (GO:0001764) 109 7 10.78 - .65 3.28E-01 1.00E00 negative regulation of cell cycle phase transition (GO:1901988) 187 12 18.49 - .65 1.69E-01 1.00E00 positive regulation of neuron differentiation (GO:0045666) 78 5 7.71 - .65 4.42E-01 1.00E00 intracellular protein transmembrane transport (GO:0065002) 47 3 4.65 - .65 6.23E-01 1.00E00 protein O-linked glycosylation (GO:0006493) 47 3 4.65 - .65 6.23E-01 1.00E00 maintenance of protein location (GO:0045185) 94 6 9.29 - .65 3.80E-01 1.00E00 histone H3 acetylation (GO:0043966) 47 3 4.65 - .65 6.23E-01 1.00E00 regulation of intracellular transport (GO:0032386) 298 19 29.46 - .64 5.95E-02 6.83E-01 regulation of response to DNA damage stimulus (GO:2001020) 204 13 20.17 - .64 1.50E-01 1.00E00 protein methylation (GO:0006479) 110 7 10.88 - .64 3.29E-01 1.00E00 protein alkylation (GO:0008213) 110 7 10.88 - .64 3.29E-01 1.00E00 embryonic epithelial tube formation (GO:0001838) 126 8 12.46 - .64 2.87E-01 1.00E00 retina development in camera-type eye (GO:0060041) 126 8 12.46 - .64 2.87E-01 1.00E00 cellular response to ionizing radiation (GO:0071479) 63 4 6.23 - .64 5.21E-01 1.00E00 epithelial cell development (GO:0002064) 189 12 18.69 - .64 1.71E-01 1.00E00 maintenance of protein location in cell (GO:0032507) 63 4 6.23 - .64 5.21E-01 1.00E00 meiotic cell cycle (GO:0051321) 205 13 20.27 - .64 1.22E-01 9.79E-01 embryonic skeletal system morphogenesis (GO:0048704) 79 5 7.81 - .64 4.43E-01 1.00E00 protein-containing complex disassembly (GO:0032984) 95 6 9.39 - .64 3.81E-01 1.00E00 positive regulation of translation (GO:0045727) 127 8 12.56 - .64 2.88E-01 1.00E00 cellular response to abiotic stimulus (GO:0071214) 223 14 22.05 - .63 1.08E-01 9.08E-01 cellular response to environmental stimulus (GO:0104004) 223 14 22.05 - .63 1.08E-01 9.08E-01 lung epithelium development (GO:0060428) 32 2 3.16 - .63 7.65E-01 1.00E00 regulation of epidermis development (GO:0045682) 48 3 4.75 - .63 6.23E-01 1.00E00 pyridine nucleotide biosynthetic process (GO:0019363) 16 1 1.58 - .63 1.00E00 1.00E00 protein transmembrane transport (GO:0071806) 48 3 4.75 - .63 6.23E-01 1.00E00 gamete generation (GO:0007276) 512 32 50.62 - .63 9.32E-03 2.05E-01 gamma-aminobutyric acid signaling pathway (GO:0007214) 16 1 1.58 - .63 1.00E00 1.00E00 endoplasmic reticulum tubular network organization (GO:0071786) 16 1 1.58 - .63 1.00E00 1.00E00 ubiquinone biosynthetic process (GO:0006744) 16 1 1.58 - .63 1.00E00 1.00E00 synaptonemal complex assembly (GO:0007130) 16 1 1.58 - .63 1.00E00 1.00E00 cotranslational protein targeting to membrane (GO:0006613) 16 1 1.58 - .63 1.00E00 1.00E00 positive regulation of protein acetylation (GO:1901985) 48 3 4.75 - .63 6.23E-01 1.00E00 uterus development (GO:0060065) 16 1 1.58 - .63 1.00E00 1.00E00 negative regulation of cardiac muscle cell proliferation (GO:0060044) 16 1 1.58 - .63 1.00E00 1.00E00 Sertoli cell differentiation (GO:0060008) 16 1 1.58 - .63 1.00E00 1.00E00 cellular amino acid metabolic process (GO:0006520) 192 12 18.98 - .63 1.38E-01 1.00E00 positive regulation of cellular respiration (GO:1901857) 16 1 1.58 - .63 1.00E00 1.00E00 acrosome assembly (GO:0001675) 16 1 1.58 - .63 1.00E00 1.00E00 response to amine (GO:0014075) 16 1 1.58 - .63 1.00E00 1.00E00 tRNA wobble uridine modification (GO:0002098) 16 1 1.58 - .63 1.00E00 1.00E00 cellular response to radiation (GO:0071478) 144 9 14.24 - .63 2.02E-01 1.00E00 epiboly involved in wound healing (GO:0090505) 16 1 1.58 - .63 1.00E00 1.00E00 action potential (GO:0001508) 64 4 6.33 - .63 5.22E-01 1.00E00 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (GO:1902176) 16 1 1.58 - .63 1.00E00 1.00E00 mRNA cleavage (GO:0006379) 16 1 1.58 - .63 1.00E00 1.00E00 quinone biosynthetic process (GO:1901663) 16 1 1.58 - .63 1.00E00 1.00E00 response to progesterone (GO:0032570) 16 1 1.58 - .63 1.00E00 1.00E00 trans-synaptic signaling (GO:0099537) 240 15 23.73 - .63 9.66E-02 8.53E-01 regulation of postsynaptic density organization (GO:1905874) 16 1 1.58 - .63 1.00E00 1.00E00 adenine nucleotide transport (GO:0051503) 16 1 1.58 - .63 1.00E00 1.00E00 wound healing, spreading of cells (GO:0044319) 16 1 1.58 - .63 1.00E00 1.00E00 lactate metabolic process (GO:0006089) 16 1 1.58 - .63 1.00E00 1.00E00 resolution of meiotic recombination intermediates (GO:0000712) 16 1 1.58 - .63 1.00E00 1.00E00 membrane fission (GO:0090148) 16 1 1.58 - .63 1.00E00 1.00E00 protein heterooligomerization (GO:0051291) 16 1 1.58 - .63 1.00E00 1.00E00 cellular response to interleukin-7 (GO:0098761) 16 1 1.58 - .63 1.00E00 1.00E00 response to interleukin-7 (GO:0098760) 16 1 1.58 - .63 1.00E00 1.00E00 glucose 6-phosphate metabolic process (GO:0051156) 16 1 1.58 - .63 1.00E00 1.00E00 mitotic intra-S DNA damage checkpoint signaling (GO:0031573) 16 1 1.58 - .63 1.00E00 1.00E00 regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043516) 32 2 3.16 - .63 7.65E-01 1.00E00 regulation of isotype switching to IgG isotypes (GO:0048302) 16 1 1.58 - .63 1.00E00 1.00E00 spliceosomal snRNP assembly (GO:0000387) 32 2 3.16 - .63 7.65E-01 1.00E00 mitotic cytokinesis (GO:0000281) 64 4 6.33 - .63 5.22E-01 1.00E00 meiotic spindle organization (GO:0000212) 16 1 1.58 - .63 1.00E00 1.00E00 response to platelet-derived growth factor (GO:0036119) 16 1 1.58 - .63 1.00E00 1.00E00 2'-deoxyribonucleotide metabolic process (GO:0009394) 32 2 3.16 - .63 7.65E-01 1.00E00 negative regulation of circadian rhythm (GO:0042754) 16 1 1.58 - .63 1.00E00 1.00E00 anaphase-promoting complex-dependent catabolic process (GO:0031145) 16 1 1.58 - .63 1.00E00 1.00E00 purine nucleotide transport (GO:0015865) 16 1 1.58 - .63 1.00E00 1.00E00 L-glutamate transmembrane transport (GO:0015813) 16 1 1.58 - .63 1.00E00 1.00E00 regulation of cellular response to hypoxia (GO:1900037) 16 1 1.58 - .63 1.00E00 1.00E00 negative regulation of transforming growth factor beta receptor signaling pathway (GO:0030512) 64 4 6.33 - .63 5.22E-01 1.00E00 branched-chain amino acid metabolic process (GO:0009081) 16 1 1.58 - .63 1.00E00 1.00E00 regulation of protein dephosphorylation (GO:0035304) 80 5 7.91 - .63 4.45E-01 1.00E00 negative regulation of programmed necrotic cell death (GO:0062099) 16 1 1.58 - .63 1.00E00 1.00E00 inositol phosphate dephosphorylation (GO:0046855) 16 1 1.58 - .63 1.00E00 1.00E00 positive regulation of triglyceride biosynthetic process (GO:0010867) 16 1 1.58 - .63 1.00E00 1.00E00 fibroblast migration (GO:0010761) 16 1 1.58 - .63 1.00E00 1.00E00 cellular response to UV (GO:0034644) 80 5 7.91 - .63 4.45E-01 1.00E00 signal transduction involved in regulation of gene expression (GO:0023019) 16 1 1.58 - .63 1.00E00 1.00E00 venous blood vessel development (GO:0060841) 16 1 1.58 - .63 1.00E00 1.00E00 growth plate cartilage development (GO:0003417) 16 1 1.58 - .63 1.00E00 1.00E00 neurotransmitter metabolic process (GO:0042133) 16 1 1.58 - .63 1.00E00 1.00E00 androgen metabolic process (GO:0008209) 16 1 1.58 - .63 1.00E00 1.00E00 regulation of exosomal secretion (GO:1903541) 16 1 1.58 - .63 1.00E00 1.00E00 metanephros morphogenesis (GO:0003338) 16 1 1.58 - .63 1.00E00 1.00E00 ncRNA 5'-end processing (GO:0034471) 16 1 1.58 - .63 1.00E00 1.00E00 striated muscle adaptation (GO:0014888) 16 1 1.58 - .63 1.00E00 1.00E00 positive regulation of heart rate (GO:0010460) 16 1 1.58 - .63 1.00E00 1.00E00 mRNA destabilization (GO:0061157) 64 4 6.33 - .63 5.22E-01 1.00E00 deoxyribose phosphate metabolic process (GO:0019692) 32 2 3.16 - .63 7.65E-01 1.00E00 atrial septum development (GO:0003283) 16 1 1.58 - .63 1.00E00 1.00E00 adult walking behavior (GO:0007628) 32 2 3.16 - .63 7.65E-01 1.00E00 adipose tissue development (GO:0060612) 32 2 3.16 - .63 7.65E-01 1.00E00 negative regulation of peptide secretion (GO:0002792) 48 3 4.75 - .63 6.23E-01 1.00E00 response to gamma radiation (GO:0010332) 48 3 4.75 - .63 6.23E-01 1.00E00 intestinal epithelial cell differentiation (GO:0060575) 16 1 1.58 - .63 1.00E00 1.00E00 seminiferous tubule development (GO:0072520) 16 1 1.58 - .63 1.00E00 1.00E00 mitochondrion organization (GO:0007005) 402 25 39.75 - .63 2.03E-02 3.49E-01 endosomal transport (GO:0016197) 193 12 19.08 - .63 1.39E-01 1.00E00 gene expression (GO:0010467) 1673 104 165.41 - .63 3.19E-07 3.72E-05 chromatin organization (GO:0006325) 564 35 55.76 - .63 4.50E-03 1.15E-01 protein modification by small protein conjugation (GO:0032446) 484 30 47.85 - .63 9.55E-03 2.09E-01 purine nucleotide biosynthetic process (GO:0006164) 113 7 11.17 - .63 2.64E-01 1.00E00 meiosis I (GO:0007127) 97 6 9.59 - .63 3.03E-01 1.00E00 cerebellum development (GO:0021549) 81 5 8.01 - .62 4.46E-01 1.00E00 lipoprotein biosynthetic process (GO:0042158) 81 5 8.01 - .62 4.46E-01 1.00E00 sensory organ morphogenesis (GO:0090596) 227 14 22.44 - .62 8.83E-02 8.34E-01 negative regulation of hormone secretion (GO:0046888) 65 4 6.43 - .62 5.24E-01 1.00E00 regulation of nucleocytoplasmic transport (GO:0046822) 114 7 11.27 - .62 2.64E-01 1.00E00 cell projection assembly (GO:0030031) 343 21 33.91 - .62 2.62E-02 4.15E-01 inner ear receptor cell development (GO:0060119) 49 3 4.84 - .62 6.25E-01 1.00E00 positive regulation of protein import into nucleus (GO:0042307) 49 3 4.84 - .62 6.25E-01 1.00E00 chromatin remodeling (GO:0006338) 131 8 12.95 - .62 2.32E-01 1.00E00 mesoderm development (GO:0007498) 82 5 8.11 - .62 3.51E-01 1.00E00 cell-cell junction assembly (GO:0007043) 82 5 8.11 - .62 3.51E-01 1.00E00 regulation of microtubule polymerization or depolymerization (GO:0031110) 82 5 8.11 - .62 3.51E-01 1.00E00 protein ubiquitination (GO:0016567) 443 27 43.80 - .62 1.10E-02 2.34E-01 regulation of DNA repair (GO:0006282) 115 7 11.37 - .62 2.65E-01 1.00E00 centrosome localization (GO:0051642) 33 2 3.26 - .61 7.66E-01 1.00E00 oocyte differentiation (GO:0009994) 33 2 3.26 - .61 7.66E-01 1.00E00 positive regulation of calcium ion transmembrane transporter activity (GO:1901021) 33 2 3.26 - .61 7.66E-01 1.00E00 necrotic cell death (GO:0070265) 33 2 3.26 - .61 7.66E-01 1.00E00 meiosis I cell cycle process (GO:0061982) 99 6 9.79 - .61 3.04E-01 1.00E00 positive regulation of histone modification (GO:0031058) 99 6 9.79 - .61 3.04E-01 1.00E00 lipoprotein metabolic process (GO:0042157) 99 6 9.79 - .61 3.04E-01 1.00E00 somite development (GO:0061053) 66 4 6.53 - .61 5.26E-01 1.00E00 regulation of cellular protein catabolic process (GO:1903362) 231 14 22.84 - .61 7.18E-02 7.39E-01 carboxylic acid catabolic process (GO:0046395) 149 9 14.73 - .61 1.63E-01 1.00E00 chromatin assembly or disassembly (GO:0006333) 100 6 9.89 - .61 3.05E-01 1.00E00 regulation of protein deacetylation (GO:0090311) 50 3 4.94 - .61 6.27E-01 1.00E00 lung alveolus development (GO:0048286) 50 3 4.94 - .61 6.27E-01 1.00E00 posttranscriptional gene silencing (GO:0016441) 50 3 4.94 - .61 6.27E-01 1.00E00 intracellular protein transport (GO:0006886) 602 36 59.52 - .60 1.83E-03 5.77E-02 regulation of chromatin organization (GO:1902275) 184 11 18.19 - .60 1.02E-01 8.84E-01 meiotic nuclear division (GO:0140013) 134 8 13.25 - .60 1.85E-01 1.00E00 germ cell development (GO:0007281) 218 13 21.55 - .60 8.12E-02 8.10E-01 cellular protein catabolic process (GO:0044257) 554 33 54.77 - .60 2.54E-03 7.54E-02 response to endoplasmic reticulum stress (GO:0034976) 202 12 19.97 - .60 9.12E-02 8.52E-01 regulation of microtubule-based process (GO:0032886) 219 13 21.65 - .60 8.16E-02 8.13E-01 protein acetylation (GO:0006473) 118 7 11.67 - .60 2.11E-01 1.00E00 purine-containing compound biosynthetic process (GO:0072522) 118 7 11.67 - .60 2.11E-01 1.00E00 sensory perception of chemical stimulus (GO:0007606) 135 8 13.35 - .60 1.85E-01 1.00E00 cell cycle (GO:0007049) 1048 62 103.62 - .60 1.65E-05 1.12E-03 striatum development (GO:0021756) 17 1 1.68 - .59 1.00E00 1.00E00 regulation of protein targeting to mitochondrion (GO:1903214) 17 1 1.68 - .59 1.00E00 1.00E00 corpus callosum development (GO:0022038) 17 1 1.68 - .59 1.00E00 1.00E00 regulation of mammary gland epithelial cell proliferation (GO:0033599) 17 1 1.68 - .59 1.00E00 1.00E00 nervous system process involved in regulation of systemic arterial blood pressure (GO:0001976) 17 1 1.68 - .59 1.00E00 1.00E00 neurotransmitter secretion (GO:0007269) 68 4 6.72 - .59 4.09E-01 1.00E00 positive regulation of T cell mediated cytotoxicity (GO:0001916) 34 2 3.36 - .59 7.68E-01 1.00E00 sphingomyelin metabolic process (GO:0006684) 17 1 1.68 - .59 1.00E00 1.00E00 reactive nitrogen species metabolic process (GO:2001057) 17 1 1.68 - .59 1.00E00 1.00E00 cellular respiration (GO:0045333) 136 8 13.45 - .59 1.86E-01 1.00E00 viral genome replication (GO:0019079) 17 1 1.68 - .59 1.00E00 1.00E00 regulation of skeletal muscle cell differentiation (GO:2001014) 17 1 1.68 - .59 1.00E00 1.00E00 glutamine metabolic process (GO:0006541) 17 1 1.68 - .59 1.00E00 1.00E00 inositol phosphate catabolic process (GO:0071545) 17 1 1.68 - .59 1.00E00 1.00E00 walking behavior (GO:0090659) 34 2 3.36 - .59 7.68E-01 1.00E00 branching involved in ureteric bud morphogenesis (GO:0001658) 34 2 3.36 - .59 7.68E-01 1.00E00 peptidyl-tyrosine autophosphorylation (GO:0038083) 17 1 1.68 - .59 1.00E00 1.00E00 protein deacetylation (GO:0006476) 51 3 5.04 - .59 4.81E-01 1.00E00 intermediate filament organization (GO:0045109) 17 1 1.68 - .59 1.00E00 1.00E00 epiboly (GO:0090504) 17 1 1.68 - .59 1.00E00 1.00E00 RNA phosphodiester bond hydrolysis (GO:0090501) 68 4 6.72 - .59 4.09E-01 1.00E00 positive regulation of organelle assembly (GO:1902117) 68 4 6.72 - .59 4.09E-01 1.00E00 cellular response to dsRNA (GO:0071359) 17 1 1.68 - .59 1.00E00 1.00E00 signal release from synapse (GO:0099643) 68 4 6.72 - .59 4.09E-01 1.00E00 protein N-linked glycosylation via asparagine (GO:0018279) 17 1 1.68 - .59 1.00E00 1.00E00 modification of synaptic structure (GO:0099563) 17 1 1.68 - .59 1.00E00 1.00E00 synaptic vesicle transport along microtubule (GO:0099517) 17 1 1.68 - .59 1.00E00 1.00E00 synaptic vesicle cytoskeletal transport (GO:0099514) 17 1 1.68 - .59 1.00E00 1.00E00 regulation of spindle organization (GO:0090224) 34 2 3.36 - .59 7.68E-01 1.00E00 negative regulation of astrocyte differentiation (GO:0048712) 17 1 1.68 - .59 1.00E00 1.00E00 positive regulation of intracellular transport (GO:0032388) 170 10 16.81 - .59 1.16E-01 9.43E-01 intracellular cholesterol transport (GO:0032367) 17 1 1.68 - .59 1.00E00 1.00E00 negative regulation of chondrocyte differentiation (GO:0032331) 17 1 1.68 - .59 1.00E00 1.00E00 glycerol metabolic process (GO:0006071) 17 1 1.68 - .59 1.00E00 1.00E00 cellular carbohydrate catabolic process (GO:0044275) 17 1 1.68 - .59 1.00E00 1.00E00 post-embryonic animal organ development (GO:0048569) 17 1 1.68 - .59 1.00E00 1.00E00 anatomical structure arrangement (GO:0048532) 17 1 1.68 - .59 1.00E00 1.00E00 regulation of response to nutrient levels (GO:0032107) 17 1 1.68 - .59 1.00E00 1.00E00 regulation of response to extracellular stimulus (GO:0032104) 17 1 1.68 - .59 1.00E00 1.00E00 anterograde synaptic vesicle transport (GO:0048490) 17 1 1.68 - .59 1.00E00 1.00E00 tongue development (GO:0043586) 17 1 1.68 - .59 1.00E00 1.00E00 positive regulation of nitric-oxide synthase activity (GO:0051000) 17 1 1.68 - .59 1.00E00 1.00E00 regulation of lysosomal lumen pH (GO:0035751) 17 1 1.68 - .59 1.00E00 1.00E00 Golgi vesicle transport (GO:0048193) 238 14 23.53 - .59 5.84E-02 6.77E-01 amyloid-beta metabolic process (GO:0050435) 17 1 1.68 - .59 1.00E00 1.00E00 regulation of mRNA polyadenylation (GO:1900363) 17 1 1.68 - .59 1.00E00 1.00E00 regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) 17 1 1.68 - .59 1.00E00 1.00E00 microtubule organizing center localization (GO:0061842) 34 2 3.36 - .59 7.68E-01 1.00E00 mRNA transcription (GO:0009299) 17 1 1.68 - .59 1.00E00 1.00E00 positive regulation of dendrite development (GO:1900006) 17 1 1.68 - .59 1.00E00 1.00E00 positive regulation of dephosphorylation (GO:0035306) 51 3 5.04 - .59 4.81E-01 1.00E00 positive regulation of nucleocytoplasmic transport (GO:0046824) 68 4 6.72 - .59 4.09E-01 1.00E00 positive regulation of mitochondrion organization (GO:0010822) 68 4 6.72 - .59 4.09E-01 1.00E00 synaptic vesicle priming (GO:0016082) 17 1 1.68 - .59 1.00E00 1.00E00 rRNA catabolic process (GO:0016075) 17 1 1.68 - .59 1.00E00 1.00E00 epithelial structure maintenance (GO:0010669) 17 1 1.68 - .59 1.00E00 1.00E00 protein import into mitochondrial matrix (GO:0030150) 17 1 1.68 - .59 1.00E00 1.00E00 establishment of protein localization to mitochondrion (GO:0072655) 68 4 6.72 - .59 4.09E-01 1.00E00 cell aging (GO:0007569) 51 3 5.04 - .59 4.81E-01 1.00E00 proteolysis involved in cellular protein catabolic process (GO:0051603) 528 31 52.20 - .59 2.57E-03 7.55E-02 regulation of microtubule cytoskeleton organization (GO:0070507) 137 8 13.55 - .59 1.87E-01 1.00E00 purine ribonucleotide biosynthetic process (GO:0009152) 103 6 10.18 - .59 2.41E-01 1.00E00 organic cyclic compound metabolic process (GO:1901360) 2289 133 226.32 - .59 5.95E-12 1.29E-09 plasma membrane bounded cell projection assembly (GO:0120031) 327 19 32.33 - .59 2.21E-02 3.68E-01 body morphogenesis (GO:0010171) 52 3 5.14 - .58 4.81E-01 1.00E00 alpha-amino acid catabolic process (GO:1901606) 52 3 5.14 - .58 4.81E-01 1.00E00 mitochondrial translation (GO:0032543) 52 3 5.14 - .58 4.81E-01 1.00E00 embryonic skeletal system development (GO:0048706) 104 6 10.28 - .58 2.41E-01 1.00E00 thymus development (GO:0048538) 52 3 5.14 - .58 4.81E-01 1.00E00 cellular nitrogen compound metabolic process (GO:0034641) 2531 146 250.24 - .58 1.51E-13 4.58E-11 organelle assembly (GO:0070925) 608 35 60.11 - .58 9.05E-04 3.34E-02 mitotic cell cycle process (GO:1903047) 452 26 44.69 - .58 4.39E-03 1.13E-01 organic acid catabolic process (GO:0016054) 157 9 15.52 - .58 1.32E-01 9.82E-01 cellular aromatic compound metabolic process (GO:0006725) 2131 122 210.69 - .58 1.64E-11 3.41E-09 positive regulation of DNA repair (GO:0045739) 70 4 6.92 - .58 4.12E-01 1.00E00 somatic diversification of immune receptors via germline recombination within a single locus (GO:0002562) 35 2 3.46 - .58 7.70E-01 1.00E00 cilium movement involved in cell motility (GO:0060294) 70 4 6.92 - .58 4.12E-01 1.00E00 positive regulation of multicellular organism growth (GO:0040018) 35 2 3.46 - .58 7.70E-01 1.00E00 somatic cell DNA recombination (GO:0016444) 35 2 3.46 - .58 7.70E-01 1.00E00 positive regulation of cardiac muscle hypertrophy (GO:0010613) 35 2 3.46 - .58 7.70E-01 1.00E00 positive regulation of muscle hypertrophy (GO:0014742) 35 2 3.46 - .58 7.70E-01 1.00E00 developmental growth (GO:0048589) 351 20 34.70 - .58 1.28E-02 2.58E-01 response to ionizing radiation (GO:0010212) 123 7 12.16 - .58 1.67E-01 1.00E00 microtubule-based transport (GO:0099111) 176 10 17.40 - .57 9.28E-02 8.59E-01 nucleus organization (GO:0006997) 106 6 10.48 - .57 2.43E-01 1.00E00 axonal transport (GO:0098930) 53 3 5.24 - .57 4.82E-01 1.00E00 signal transduction by p53 class mediator (GO:0072331) 71 4 7.02 - .57 4.14E-01 1.00E00 growth (GO:0040007) 355 20 35.10 - .57 1.03E-02 2.24E-01 DNA conformation change (GO:0071103) 160 9 15.82 - .57 1.04E-01 8.97E-01 cellular response to light stimulus (GO:0071482) 89 5 8.80 - .57 2.77E-01 1.00E00 mitotic cell cycle (GO:0000278) 517 29 51.12 - .57 1.36E-03 4.63E-02 pallium development (GO:0021543) 126 7 12.46 - .56 1.68E-01 1.00E00 nucleic acid phosphodiester bond hydrolysis (GO:0090305) 108 6 10.68 - .56 1.89E-01 1.00E00 aerobic respiration (GO:0009060) 108 6 10.68 - .56 1.89E-01 1.00E00 cellular ketone metabolic process (GO:0042180) 54 3 5.34 - .56 4.84E-01 1.00E00 regulation of mitotic metaphase/anaphase transition (GO:0030071) 54 3 5.34 - .56 4.84E-01 1.00E00 positive regulation of gluconeogenesis (GO:0045722) 18 1 1.78 - .56 1.00E00 1.00E00 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent (GO:0002486) 18 1 1.78 - .56 1.00E00 1.00E00 regulation of cholesterol biosynthetic process (GO:0045540) 18 1 1.78 - .56 1.00E00 1.00E00 negative regulation of cellular senescence (GO:2000773) 18 1 1.78 - .56 1.00E00 1.00E00 ubiquinone metabolic process (GO:0006743) 18 1 1.78 - .56 1.00E00 1.00E00 limb development (GO:0060173) 144 8 14.24 - .56 1.17E-01 9.50E-01 phosphatidic acid biosynthetic process (GO:0006654) 18 1 1.78 - .56 1.00E00 1.00E00 regulation of cell cycle checkpoint (GO:1901976) 36 2 3.56 - .56 5.77E-01 1.00E00 mitotic G2 DNA damage checkpoint signaling (GO:0007095) 36 2 3.56 - .56 5.77E-01 1.00E00 mitotic sister chromatid cohesion (GO:0007064) 18 1 1.78 - .56 1.00E00 1.00E00 regulation of mitochondrial depolarization (GO:0051900) 18 1 1.78 - .56 1.00E00 1.00E00 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254) 18 1 1.78 - .56 1.00E00 1.00E00 glandular epithelial cell development (GO:0002068) 18 1 1.78 - .56 1.00E00 1.00E00 pseudouridine synthesis (GO:0001522) 18 1 1.78 - .56 1.00E00 1.00E00 DNA-templated transcription, termination (GO:0006353) 18 1 1.78 - .56 1.00E00 1.00E00 regulation of fibroblast apoptotic process (GO:2000269) 18 1 1.78 - .56 1.00E00 1.00E00 RNA 5'-end processing (GO:0000966) 18 1 1.78 - .56 1.00E00 1.00E00 neural nucleus development (GO:0048857) 18 1 1.78 - .56 1.00E00 1.00E00 peptidyl-asparagine modification (GO:0018196) 18 1 1.78 - .56 1.00E00 1.00E00 protein modification by small protein conjugation or removal (GO:0070647) 594 33 58.73 - .56 4.68E-04 1.94E-02 appendage development (GO:0048736) 144 8 14.24 - .56 1.17E-01 9.49E-01 intracellular sterol transport (GO:0032366) 18 1 1.78 - .56 1.00E00 1.00E00 regulation of sterol biosynthetic process (GO:0106118) 18 1 1.78 - .56 1.00E00 1.00E00 regulation of neuron projection regeneration (GO:0070570) 36 2 3.56 - .56 5.77E-01 1.00E00 multicellular organismal water homeostasis (GO:0050891) 36 2 3.56 - .56 5.77E-01 1.00E00 negative regulation of NF-kappaB transcription factor activity (GO:0032088) 72 4 7.12 - .56 3.18E-01 1.00E00 chaperone-mediated protein complex assembly (GO:0051131) 18 1 1.78 - .56 1.00E00 1.00E00 pyroptosis (GO:0070269) 18 1 1.78 - .56 1.00E00 1.00E00 paraxial mesoderm development (GO:0048339) 18 1 1.78 - .56 1.00E00 1.00E00 regulation of renal sodium excretion (GO:0035813) 18 1 1.78 - .56 1.00E00 1.00E00 positive regulation of mitochondrial membrane permeability (GO:0035794) 18 1 1.78 - .56 1.00E00 1.00E00 mitochondrion transport along microtubule (GO:0047497) 18 1 1.78 - .56 1.00E00 1.00E00 embryonic camera-type eye development (GO:0031076) 36 2 3.56 - .56 5.77E-01 1.00E00 purine ribonucleoside monophosphate biosynthetic process (GO:0009168) 18 1 1.78 - .56 1.00E00 1.00E00 purine nucleoside monophosphate biosynthetic process (GO:0009127) 18 1 1.78 - .56 1.00E00 1.00E00 regulation of GTP binding (GO:1904424) 18 1 1.78 - .56 1.00E00 1.00E00 inner ear auditory receptor cell differentiation (GO:0042491) 36 2 3.56 - .56 5.77E-01 1.00E00 phosphorylated carbohydrate dephosphorylation (GO:0046838) 18 1 1.78 - .56 1.00E00 1.00E00 middle ear morphogenesis (GO:0042474) 18 1 1.78 - .56 1.00E00 1.00E00 positive regulation of protein export from nucleus (GO:0046827) 18 1 1.78 - .56 1.00E00 1.00E00 retina layer formation (GO:0010842) 18 1 1.78 - .56 1.00E00 1.00E00 acid secretion (GO:0046717) 18 1 1.78 - .56 1.00E00 1.00E00 dendritic spine development (GO:0060996) 36 2 3.56 - .56 5.77E-01 1.00E00 tetrahydrofolate metabolic process (GO:0046653) 18 1 1.78 - .56 1.00E00 1.00E00 establishment of mitochondrion localization, microtubule-mediated (GO:0034643) 18 1 1.78 - .56 1.00E00 1.00E00 regulation of lamellipodium assembly (GO:0010591) 36 2 3.56 - .56 5.77E-01 1.00E00 negative regulation of transposition (GO:0010529) 18 1 1.78 - .56 1.00E00 1.00E00 regulation of transposition (GO:0010528) 18 1 1.78 - .56 1.00E00 1.00E00 endocardial cushion formation (GO:0003272) 18 1 1.78 - .56 1.00E00 1.00E00 neuroepithelial cell differentiation (GO:0060563) 18 1 1.78 - .56 1.00E00 1.00E00 small molecule catabolic process (GO:0044282) 236 13 23.33 - .56 3.36E-02 4.85E-01 nuclear-transcribed mRNA catabolic process (GO:0000956) 91 5 9.00 - .56 2.79E-01 1.00E00 peptidyl-lysine methylation (GO:0018022) 73 4 7.22 - .55 3.18E-01 1.00E00 sulfur compound biosynthetic process (GO:0044272) 73 4 7.22 - .55 3.18E-01 1.00E00 regulation of RNA stability (GO:0043487) 146 8 14.44 - .55 1.18E-01 9.54E-01 neural precursor cell proliferation (GO:0061351) 73 4 7.22 - .55 3.18E-01 1.00E00 regulation of metaphase/anaphase transition of cell cycle (GO:1902099) 55 3 5.44 - .55 4.86E-01 1.00E00 neuron projection extension (GO:1990138) 55 3 5.44 - .55 4.86E-01 1.00E00 ribonucleotide biosynthetic process (GO:0009260) 110 6 10.88 - .55 1.91E-01 1.00E00 meiotic cell cycle process (GO:1903046) 147 8 14.53 - .55 1.19E-01 9.60E-01 male gamete generation (GO:0048232) 405 22 40.04 - .55 3.46E-03 9.52E-02 spermatogenesis (GO:0007283) 387 21 38.26 - .55 4.84E-03 1.23E-01 protein targeting to vacuole (GO:0006623) 37 2 3.66 - .55 5.77E-01 1.00E00 mitotic DNA integrity checkpoint signaling (GO:0044774) 74 4 7.32 - .55 3.19E-01 1.00E00 Schwann cell differentiation (GO:0014037) 37 2 3.66 - .55 5.77E-01 1.00E00 mitochondrial RNA metabolic process (GO:0000959) 37 2 3.66 - .55 5.77E-01 1.00E00 oxidative phosphorylation (GO:0006119) 74 4 7.32 - .55 3.19E-01 1.00E00 regulation of cAMP-mediated signaling (GO:0043949) 37 2 3.66 - .55 5.77E-01 1.00E00 negative chemotaxis (GO:0050919) 37 2 3.66 - .55 5.77E-01 1.00E00 response to dsRNA (GO:0043331) 37 2 3.66 - .55 5.77E-01 1.00E00 deoxyribonucleotide metabolic process (GO:0009262) 37 2 3.66 - .55 5.77E-01 1.00E00 positive regulation of protein dephosphorylation (GO:0035307) 37 2 3.66 - .55 5.77E-01 1.00E00 somatic stem cell population maintenance (GO:0035019) 37 2 3.66 - .55 5.77E-01 1.00E00 negative regulation of mitotic nuclear division (GO:0045839) 37 2 3.66 - .55 5.77E-01 1.00E00 positive regulation of chromatin organization (GO:1905269) 111 6 10.97 - .55 1.92E-01 1.00E00 macromolecule biosynthetic process (GO:0009059) 1060 57 104.80 - .54 5.55E-07 6.02E-05 cell cycle process (GO:0022402) 689 37 68.12 - .54 8.34E-05 4.49E-03 hippocampus development (GO:0021766) 56 3 5.54 - .54 3.68E-01 1.00E00 nucleosome assembly (GO:0006334) 56 3 5.54 - .54 3.68E-01 1.00E00 protein localization to vacuole (GO:0072665) 56 3 5.54 - .54 3.68E-01 1.00E00 alcohol biosynthetic process (GO:0046165) 75 4 7.42 - .54 3.21E-01 1.00E00 nucleotide biosynthetic process (GO:0009165) 150 8 14.83 - .54 9.25E-02 8.57E-01 peptide metabolic process (GO:0006518) 413 22 40.83 - .54 2.80E-03 8.09E-02 heterocycle metabolic process (GO:0046483) 2085 111 206.15 - .54 1.60E-13 4.76E-11 cerebral cortex development (GO:0021987) 94 5 9.29 - .54 2.16E-01 1.00E00 mRNA catabolic process (GO:0006402) 113 6 11.17 - .54 1.48E-01 1.00E00 negative regulation of oxidative stress-induced neuron death (GO:1903204) 19 1 1.88 - .53 1.00E00 1.00E00 trachea development (GO:0060438) 19 1 1.88 - .53 1.00E00 1.00E00 positive regulation of epidermal cell differentiation (GO:0045606) 19 1 1.88 - .53 1.00E00 1.00E00 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway (GO:0002484) 19 1 1.88 - .53 1.00E00 1.00E00 antigen processing and presentation of endogenous peptide antigen via MHC class Ib (GO:0002476) 19 1 1.88 - .53 1.00E00 1.00E00 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (GO:0007187) 19 1 1.88 - .53 1.00E00 1.00E00 homologous chromosome pairing at meiosis (GO:0007129) 38 2 3.76 - .53 5.79E-01 1.00E00 maternal process involved in female pregnancy (GO:0060135) 38 2 3.76 - .53 5.79E-01 1.00E00 tRNA wobble base modification (GO:0002097) 19 1 1.88 - .53 1.00E00 1.00E00 negative regulation of protein kinase B signaling (GO:0051898) 38 2 3.76 - .53 5.79E-01 1.00E00 oocyte maturation (GO:0001556) 19 1 1.88 - .53 1.00E00 1.00E00 cellular response to estradiol stimulus (GO:0071392) 19 1 1.88 - .53 1.00E00 1.00E00 mitotic recombination (GO:0006312) 19 1 1.88 - .53 1.00E00 1.00E00 negative regulation of DNA biosynthetic process (GO:2000279) 38 2 3.76 - .53 5.79E-01 1.00E00 positive regulation of amyloid-beta formation (GO:1902004) 19 1 1.88 - .53 1.00E00 1.00E00 peptidyl-proline modification (GO:0018208) 38 2 3.76 - .53 5.79E-01 1.00E00 positive regulation of mitochondrial fission (GO:0090141) 19 1 1.88 - .53 1.00E00 1.00E00 negative regulation of telomere maintenance via telomerase (GO:0032211) 19 1 1.88 - .53 1.00E00 1.00E00 regulation of steroid hormone biosynthetic process (GO:0090030) 19 1 1.88 - .53 1.00E00 1.00E00 response to salt stress (GO:0009651) 19 1 1.88 - .53 1.00E00 1.00E00 synaptonemal complex organization (GO:0070193) 19 1 1.88 - .53 1.00E00 1.00E00 peroxisomal membrane transport (GO:0015919) 19 1 1.88 - .53 1.00E00 1.00E00 benzene-containing compound metabolic process (GO:0042537) 19 1 1.88 - .53 1.00E00 1.00E00 glutamine family amino acid catabolic process (GO:0009065) 19 1 1.88 - .53 1.00E00 1.00E00 muscle cell cellular homeostasis (GO:0046716) 19 1 1.88 - .53 1.00E00 1.00E00 DNA strand elongation (GO:0022616) 19 1 1.88 - .53 1.00E00 1.00E00 mammary gland lobule development (GO:0061377) 19 1 1.88 - .53 1.00E00 1.00E00 mammary gland alveolus development (GO:0060749) 19 1 1.88 - .53 1.00E00 1.00E00 retrograde axonal transport (GO:0008090) 19 1 1.88 - .53 1.00E00 1.00E00 negative regulation of necrotic cell death (GO:0060547) 19 1 1.88 - .53 1.00E00 1.00E00 Golgi organization (GO:0007030) 114 6 11.27 - .53 1.48E-01 1.00E00 protein acylation (GO:0043543) 153 8 15.13 - .53 7.24E-02 7.39E-01 cell-cell signaling by wnt (GO:0198738) 192 10 18.98 - .53 4.65E-02 5.77E-01 nuclear export (GO:0051168) 96 5 9.49 - .53 2.18E-01 1.00E00 Wnt signaling pathway (GO:0016055) 192 10 18.98 - .53 4.65E-02 5.77E-01 nucleoside phosphate biosynthetic process (GO:1901293) 154 8 15.23 - .53 7.24E-02 7.39E-01 histone methylation (GO:0016571) 77 4 7.61 - .53 2.45E-01 1.00E00 regulation of mRNA stability (GO:0043488) 135 7 13.35 - .52 1.04E-01 8.93E-01 mitotic cell cycle checkpoint signaling (GO:0007093) 116 6 11.47 - .52 1.50E-01 1.00E00 peptidyl-lysine modification (GO:0018205) 232 12 22.94 - .52 2.35E-02 3.85E-01 regulation of mitotic sister chromatid separation (GO:0010965) 58 3 5.73 - .52 3.69E-01 1.00E00 ribose phosphate biosynthetic process (GO:0046390) 116 6 11.47 - .52 1.50E-01 1.00E00 establishment of protein localization to organelle (GO:0072594) 271 14 26.79 - .52 1.20E-02 2.46E-01 eye morphogenesis (GO:0048592) 136 7 13.45 - .52 1.04E-01 8.97E-01 regulation of cellular senescence (GO:2000772) 39 2 3.86 - .52 5.81E-01 1.00E00 cilium-dependent cell motility (GO:0060285) 78 4 7.71 - .52 2.45E-01 1.00E00 sister chromatid cohesion (GO:0007062) 39 2 3.86 - .52 5.81E-01 1.00E00 cilium or flagellum-dependent cell motility (GO:0001539) 78 4 7.71 - .52 2.45E-01 1.00E00 DNA packaging (GO:0006323) 117 6 11.57 - .52 1.51E-01 1.00E00 negative regulation of TOR signaling (GO:0032007) 39 2 3.86 - .52 5.81E-01 1.00E00 respiratory electron transport chain (GO:0022904) 78 4 7.71 - .52 2.45E-01 1.00E00 phospholipid dephosphorylation (GO:0046839) 39 2 3.86 - .52 5.81E-01 1.00E00 gene silencing by miRNA (GO:0035195) 39 2 3.86 - .52 5.81E-01 1.00E00 epithelial cell morphogenesis (GO:0003382) 39 2 3.86 - .52 5.81E-01 1.00E00 receptor localization to synapse (GO:0097120) 39 2 3.86 - .52 5.81E-01 1.00E00 positive regulation of mRNA catabolic process (GO:0061014) 78 4 7.71 - .52 2.45E-01 1.00E00 protein monoubiquitination (GO:0006513) 59 3 5.83 - .51 3.71E-01 1.00E00 glycosyl compound metabolic process (GO:1901657) 59 3 5.83 - .51 3.71E-01 1.00E00 regulation of DNA metabolic process (GO:0051052) 335 17 33.12 - .51 4.49E-03 1.15E-01 cellular response to DNA damage stimulus (GO:0006974) 632 32 62.49 - .51 5.35E-05 3.12E-03 histone modification (GO:0016570) 316 16 31.24 - .51 4.86E-03 1.23E-01 maintenance of cell number (GO:0098727) 119 6 11.77 - .51 1.15E-01 9.44E-01 positive regulation of myoblast differentiation (GO:0045663) 20 1 1.98 - .51 1.00E00 1.00E00 antigen processing and presentation of peptide antigen via MHC class Ib (GO:0002428) 20 1 1.98 - .51 1.00E00 1.00E00 subpallium development (GO:0021544) 20 1 1.98 - .51 1.00E00 1.00E00 regulation of sister chromatid cohesion (GO:0007063) 20 1 1.98 - .51 1.00E00 1.00E00 eye photoreceptor cell differentiation (GO:0001754) 40 2 3.95 - .51 5.84E-01 1.00E00 glutamate metabolic process (GO:0006536) 20 1 1.98 - .51 1.00E00 1.00E00 morphogenesis of an epithelial sheet (GO:0002011) 40 2 3.95 - .51 5.84E-01 1.00E00 positive regulation of RNA splicing (GO:0033120) 40 2 3.95 - .51 5.84E-01 1.00E00 organic hydroxy compound catabolic process (GO:1901616) 40 2 3.95 - .51 5.84E-01 1.00E00 muscle cell proliferation (GO:0033002) 20 1 1.98 - .51 1.00E00 1.00E00 peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine (GO:0018231) 20 1 1.98 - .51 1.00E00 1.00E00 peptidyl-L-cysteine S-palmitoylation (GO:0018230) 20 1 1.98 - .51 1.00E00 1.00E00 positive regulation of behavior (GO:0048520) 20 1 1.98 - .51 1.00E00 1.00E00 post-translational protein modification (GO:0043687) 20 1 1.98 - .51 1.00E00 1.00E00 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway (GO:1901028) 20 1 1.98 - .51 1.00E00 1.00E00 glucose transmembrane transport (GO:1904659) 20 1 1.98 - .51 1.00E00 1.00E00 hexose transmembrane transport (GO:0008645) 20 1 1.98 - .51 1.00E00 1.00E00 intrinsic apoptotic signaling pathway in response to oxidative stress (GO:0008631) 20 1 1.98 - .51 1.00E00 1.00E00 attachment of spindle microtubules to kinetochore (GO:0008608) 20 1 1.98 - .51 1.00E00 1.00E00 phosphatidylglycerol metabolic process (GO:0046471) 20 1 1.98 - .51 1.00E00 1.00E00 mating behavior (GO:0007617) 20 1 1.98 - .51 1.00E00 1.00E00 protein polyubiquitination (GO:0000209) 201 10 19.87 - .50 2.85E-02 4.42E-01 covalent chromatin modification (GO:0016569) 322 16 31.84 - .50 3.81E-03 1.02E-01 sensory perception of sound (GO:0007605) 121 6 11.96 - .50 1.17E-01 9.50E-01 protein localization to cell junction (GO:1902414) 81 4 8.01 - .50 2.50E-01 1.00E00 mitochondrial gene expression (GO:0140053) 81 4 8.01 - .50 2.50E-01 1.00E00 endocrine system development (GO:0035270) 81 4 8.01 - .50 2.50E-01 1.00E00 microtubule cytoskeleton organization (GO:0000226) 446 22 44.10 - .50 5.35E-04 2.20E-02 histone lysine methylation (GO:0034968) 61 3 6.03 - .50 2.79E-01 1.00E00 positive regulation of DNA metabolic process (GO:0051054) 204 10 20.17 - .50 2.21E-02 3.68E-01 tumor necrosis factor-mediated signaling pathway (GO:0033209) 41 2 4.05 - .49 4.30E-01 1.00E00 embryonic cranial skeleton morphogenesis (GO:0048701) 41 2 4.05 - .49 4.30E-01 1.00E00 anterograde axonal transport (GO:0008089) 41 2 4.05 - .49 4.30E-01 1.00E00 negative regulation of mRNA metabolic process (GO:1903312) 82 4 8.11 - .49 1.87E-01 1.00E00 cellular macromolecule biosynthetic process (GO:0034645) 1049 51 103.72 - .49 2.13E-08 3.19E-06 microtubule-based movement (GO:0007018) 288 14 28.47 - .49 5.83E-03 1.42E-01 positive regulation of response to DNA damage stimulus (GO:2001022) 103 5 10.18 - .49 1.28E-01 9.66E-01 macromolecule deacylation (GO:0098732) 62 3 6.13 - .49 2.79E-01 1.00E00 protein deacylation (GO:0035601) 62 3 6.13 - .49 2.79E-01 1.00E00 regulation of mRNA catabolic process (GO:0061013) 145 7 14.34 - .49 6.26E-02 7.06E-01 chromosome organization (GO:0051276) 830 40 82.06 - .49 5.22E-07 5.70E-05 negative regulation of DNA metabolic process (GO:0051053) 104 5 10.28 - .49 1.29E-01 9.69E-01 cell division (GO:0051301) 459 22 45.38 - .48 2.54E-04 1.18E-02 microtubule-based process (GO:0007017) 648 31 64.07 - .48 1.04E-05 7.86E-04 branching involved in mammary gland duct morphogenesis (GO:0060444) 21 1 2.08 - .48 7.16E-01 1.00E00 mitochondrial cytochrome c oxidase assembly (GO:0033617) 21 1 2.08 - .48 7.16E-01 1.00E00 dopamine receptor signaling pathway (GO:0007212) 21 1 2.08 - .48 7.16E-01 1.00E00 isoprenoid metabolic process (GO:0006720) 63 3 6.23 - .48 2.80E-01 1.00E00 reciprocal meiotic recombination (GO:0007131) 42 2 4.15 - .48 4.30E-01 1.00E00 blastocyst development (GO:0001824) 126 6 12.46 - .48 9.04E-02 8.46E-01 somatic diversification of immune receptors (GO:0002200) 42 2 4.15 - .48 4.30E-01 1.00E00 reciprocal homologous recombination (GO:0140527) 42 2 4.15 - .48 4.30E-01 1.00E00 neurotrophin signaling pathway (GO:0038179) 21 1 2.08 - .48 7.16E-01 1.00E00 lens morphogenesis in camera-type eye (GO:0002089) 21 1 2.08 - .48 7.16E-01 1.00E00 regulation of oxidative phosphorylation (GO:0002082) 21 1 2.08 - .48 7.16E-01 1.00E00 protein localization to chromosome, centromeric region (GO:0071459) 21 1 2.08 - .48 7.16E-01 1.00E00 regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902108) 21 1 2.08 - .48 7.16E-01 1.00E00 negative regulation of nuclear division (GO:0051784) 42 2 4.15 - .48 4.30E-01 1.00E00 regulation of sister chromatid segregation (GO:0033045) 63 3 6.23 - .48 2.80E-01 1.00E00 establishment of mitochondrion localization (GO:0051654) 21 1 2.08 - .48 7.16E-01 1.00E00 regulation of chromosome separation (GO:1905818) 63 3 6.23 - .48 2.80E-01 1.00E00 positive regulation of membrane permeability (GO:1905710) 21 1 2.08 - .48 7.16E-01 1.00E00 protein sumoylation (GO:0016925) 21 1 2.08 - .48 7.16E-01 1.00E00 regulation of DNA methylation (GO:0044030) 21 1 2.08 - .48 7.16E-01 1.00E00 membrane raft organization (GO:0031579) 21 1 2.08 - .48 7.16E-01 1.00E00 muscle adaptation (GO:0043500) 21 1 2.08 - .48 7.16E-01 1.00E00 necroptotic process (GO:0070266) 21 1 2.08 - .48 7.16E-01 1.00E00 positive regulation of epithelial cell differentiation (GO:0030858) 42 2 4.15 - .48 4.30E-01 1.00E00 regulation of ubiquitin protein ligase activity (GO:1904666) 21 1 2.08 - .48 7.16E-01 1.00E00 G2/M transition of mitotic cell cycle (GO:0000086) 42 2 4.15 - .48 4.30E-01 1.00E00 ribonucleoside monophosphate biosynthetic process (GO:0009156) 21 1 2.08 - .48 7.16E-01 1.00E00 electron transport chain (GO:0022900) 84 4 8.31 - .48 1.88E-01 1.00E00 endochondral bone growth (GO:0003416) 21 1 2.08 - .48 7.16E-01 1.00E00 ketone biosynthetic process (GO:0042181) 21 1 2.08 - .48 7.16E-01 1.00E00 phosphatidic acid metabolic process (GO:0046473) 21 1 2.08 - .48 7.16E-01 1.00E00 neuronal stem cell population maintenance (GO:0097150) 21 1 2.08 - .48 7.16E-01 1.00E00 body fluid secretion (GO:0007589) 42 2 4.15 - .48 4.30E-01 1.00E00 nucleobase-containing compound biosynthetic process (GO:0034654) 551 26 54.48 - .48 4.17E-05 2.54E-03 protein-DNA complex assembly (GO:0065004) 106 5 10.48 - .48 1.31E-01 9.75E-01 DNA modification (GO:0006304) 64 3 6.33 - .47 2.81E-01 1.00E00 vesicle-mediated transport to the plasma membrane (GO:0098876) 107 5 10.58 - .47 9.80E-02 8.60E-01 regulation of mitotic sister chromatid segregation (GO:0033047) 43 2 4.25 - .47 4.32E-01 1.00E00 homologous recombination (GO:0035825) 43 2 4.25 - .47 4.32E-01 1.00E00 multicellular organismal signaling (GO:0035637) 86 4 8.50 - .47 1.92E-01 1.00E00 fatty acid oxidation (GO:0019395) 65 3 6.43 - .47 2.83E-01 1.00E00 positive regulation of protein localization to nucleus (GO:1900182) 87 4 8.60 - .47 1.42E-01 1.00E00 negative regulation of protein modification by small protein conjugation or removal (GO:1903321) 87 4 8.60 - .47 1.42E-01 1.00E00 amide biosynthetic process (GO:0043604) 393 18 38.86 - .46 4.41E-04 1.85E-02 regulation of signal transduction by p53 class mediator (GO:1901796) 66 3 6.53 - .46 2.10E-01 1.00E00 flagellated sperm motility (GO:0030317) 66 3 6.53 - .46 2.10E-01 1.00E00 positive regulation of epidermis development (GO:0045684) 22 1 2.18 - .46 7.17E-01 1.00E00 gastrulation with mouth forming second (GO:0001702) 22 1 2.18 - .46 7.17E-01 1.00E00 early endosome to late endosome transport (GO:0045022) 22 1 2.18 - .46 7.17E-01 1.00E00 protein K48-linked deubiquitination (GO:0071108) 22 1 2.18 - .46 7.17E-01 1.00E00 maintenance of protein location in nucleus (GO:0051457) 22 1 2.18 - .46 7.17E-01 1.00E00 COPII-coated vesicle budding (GO:0090114) 22 1 2.18 - .46 7.17E-01 1.00E00 regulation of excretion (GO:0044062) 22 1 2.18 - .46 7.17E-01 1.00E00 peroxisomal transport (GO:0043574) 22 1 2.18 - .46 7.17E-01 1.00E00 protein peptidyl-prolyl isomerization (GO:0000413) 22 1 2.18 - .46 7.17E-01 1.00E00 steroid hormone mediated signaling pathway (GO:0043401) 44 2 4.35 - .46 4.34E-01 1.00E00 exploration behavior (GO:0035640) 22 1 2.18 - .46 7.17E-01 1.00E00 mitochondrial genome maintenance (GO:0000002) 22 1 2.18 - .46 7.17E-01 1.00E00 developmental induction (GO:0031128) 22 1 2.18 - .46 7.17E-01 1.00E00 negative regulation of microtubule polymerization or depolymerization (GO:0031111) 44 2 4.35 - .46 4.34E-01 1.00E00 regulation of endoplasmic reticulum unfolded protein response (GO:1900101) 22 1 2.18 - .46 7.17E-01 1.00E00 negative regulation of histone methylation (GO:0031061) 22 1 2.18 - .46 7.17E-01 1.00E00 regulation of programmed necrotic cell death (GO:0062098) 22 1 2.18 - .46 7.17E-01 1.00E00 regulation of centrosome duplication (GO:0010824) 44 2 4.35 - .46 4.34E-01 1.00E00 collagen fibril organization (GO:0030199) 44 2 4.35 - .46 4.34E-01 1.00E00 microtubule anchoring (GO:0034453) 22 1 2.18 - .46 7.17E-01 1.00E00 pituitary gland development (GO:0021983) 22 1 2.18 - .46 7.17E-01 1.00E00 establishment of protein localization to vacuole (GO:0072666) 44 2 4.35 - .46 4.34E-01 1.00E00 negative regulation of cartilage development (GO:0061037) 22 1 2.18 - .46 7.17E-01 1.00E00 positive regulation of gene expression, epigenetic (GO:0045815) 22 1 2.18 - .46 7.17E-01 1.00E00 regulation of DNA recombination (GO:0000018) 89 4 8.80 - .45 1.43E-01 1.00E00 protein autoubiquitination (GO:0051865) 67 3 6.62 - .45 2.10E-01 1.00E00 modification-dependent protein catabolic process (GO:0019941) 470 21 46.47 - .45 7.73E-05 4.22E-03 post-transcriptional gene silencing by RNA (GO:0035194) 45 2 4.45 - .45 4.38E-01 1.00E00 cellular response to heat (GO:0034605) 45 2 4.45 - .45 4.38E-01 1.00E00 cellular protein-containing complex assembly (GO:0034622) 611 27 60.41 - .45 3.82E-06 3.24E-04 acyl-CoA metabolic process (GO:0006637) 68 3 6.72 - .45 2.10E-01 1.00E00 regulation of cytokinesis (GO:0032465) 68 3 6.72 - .45 2.10E-01 1.00E00 sperm motility (GO:0097722) 68 3 6.72 - .45 2.10E-01 1.00E00 thioester metabolic process (GO:0035383) 68 3 6.72 - .45 2.10E-01 1.00E00 double-strand break repair via homologous recombination (GO:0000724) 91 4 9.00 - .44 1.46E-01 1.00E00 modification-dependent macromolecule catabolic process (GO:0043632) 479 21 47.36 - .44 4.55E-05 2.73E-03 ubiquitin-dependent protein catabolic process (GO:0006511) 459 20 45.38 - .44 6.30E-05 3.59E-03 dendrite morphogenesis (GO:0048813) 69 3 6.82 - .44 2.12E-01 1.00E00 cell cycle checkpoint signaling (GO:0000075) 138 6 13.64 - .44 3.98E-02 5.47E-01 nucleobase-containing compound transport (GO:0015931) 161 7 15.92 - .44 2.87E-02 4.45E-01 regulation of lamellipodium organization (GO:1902743) 46 2 4.55 - .44 3.18E-01 1.00E00 response to X-ray (GO:0010165) 23 1 2.27 - .44 7.19E-01 1.00E00 male meiosis I (GO:0007141) 23 1 2.27 - .44 7.19E-01 1.00E00 regulation of protein localization to synapse (GO:1902473) 23 1 2.27 - .44 7.19E-01 1.00E00 virion assembly (GO:0019068) 23 1 2.27 - .44 7.19E-01 1.00E00 cell cycle G2/M phase transition (GO:0044839) 46 2 4.55 - .44 3.18E-01 1.00E00 regulation of telomerase activity (GO:0051972) 46 2 4.55 - .44 3.18E-01 1.00E00 nuclear DNA replication (GO:0033260) 23 1 2.27 - .44 7.19E-01 1.00E00 negative regulation of peptide hormone secretion (GO:0090278) 46 2 4.55 - .44 3.18E-01 1.00E00 skeletal muscle fiber development (GO:0048741) 23 1 2.27 - .44 7.19E-01 1.00E00 recombinational repair (GO:0000725) 92 4 9.10 - .44 1.07E-01 9.01E-01 cell death in response to oxidative stress (GO:0036473) 23 1 2.27 - .44 7.19E-01 1.00E00 negative regulation of defense response to virus (GO:0050687) 23 1 2.27 - .44 7.19E-01 1.00E00 neuron cellular homeostasis (GO:0070050) 23 1 2.27 - .44 7.19E-01 1.00E00 sulfur amino acid metabolic process (GO:0000096) 23 1 2.27 - .44 7.19E-01 1.00E00 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146) 46 2 4.55 - .44 3.18E-01 1.00E00 regulation of establishment of protein localization to mitochondrion (GO:1903747) 23 1 2.27 - .44 7.19E-01 1.00E00 regulation of androgen receptor signaling pathway (GO:0060765) 23 1 2.27 - .44 7.19E-01 1.00E00 negative regulation of DNA replication (GO:0008156) 23 1 2.27 - .44 7.19E-01 1.00E00 smoothened signaling pathway (GO:0007224) 70 3 6.92 - .43 2.14E-01 1.00E00 DNA recombination (GO:0006310) 187 8 18.49 - .43 1.17E-02 2.44E-01 nuclear division (GO:0000280) 258 11 25.51 - .43 2.53E-03 7.53E-02 histone deacetylation (GO:0016575) 47 2 4.65 - .43 3.18E-01 1.00E00 histone acetylation (GO:0016573) 94 4 9.29 - .43 1.08E-01 9.08E-01 glutamine family amino acid metabolic process (GO:0009064) 47 2 4.65 - .43 3.18E-01 1.00E00 synaptic vesicle exocytosis (GO:0016079) 47 2 4.65 - .43 3.18E-01 1.00E00 proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161) 282 12 27.88 - .43 1.86E-03 5.85E-02 proteasomal protein catabolic process (GO:0010498) 307 13 30.35 - .43 1.03E-03 3.70E-02 regulation of double-strand break repair (GO:2000779) 71 3 7.02 - .43 1.56E-01 1.00E00 mitotic DNA damage checkpoint signaling (GO:0044773) 71 3 7.02 - .43 1.56E-01 1.00E00 DNA integrity checkpoint signaling (GO:0031570) 95 4 9.39 - .43 1.09E-01 9.09E-01 nucleobase-containing compound metabolic process (GO:0006139) 1982 83 195.96 - .42 2.86E-20 1.97E-17 respiratory system process (GO:0003016) 24 1 2.37 - .42 7.22E-01 1.00E00 SMAD protein signal transduction (GO:0060395) 48 2 4.75 - .42 3.19E-01 1.00E00 antigen processing and presentation via MHC class Ib (GO:0002475) 24 1 2.37 - .42 7.22E-01 1.00E00 regulation of water loss via skin (GO:0033561) 24 1 2.37 - .42 7.22E-01 1.00E00 neuronal action potential (GO:0019228) 24 1 2.37 - .42 7.22E-01 1.00E00 cell cycle DNA replication (GO:0044786) 24 1 2.37 - .42 7.22E-01 1.00E00 embryonic camera-type eye morphogenesis (GO:0048596) 24 1 2.37 - .42 7.22E-01 1.00E00 regulation of phosphoprotein phosphatase activity (GO:0043666) 48 2 4.75 - .42 3.19E-01 1.00E00 gene silencing by RNA (GO:0031047) 72 3 7.12 - .42 1.57E-01 1.00E00 cell communication involved in cardiac conduction (GO:0086065) 24 1 2.37 - .42 7.22E-01 1.00E00 autophagosome maturation (GO:0097352) 24 1 2.37 - .42 7.22E-01 1.00E00 cellular protein-containing complex localization (GO:0034629) 24 1 2.37 - .42 7.22E-01 1.00E00 centromere complex assembly (GO:0034508) 24 1 2.37 - .42 7.22E-01 1.00E00 transcription by RNA polymerase II (GO:0006366) 145 6 14.34 - .42 3.06E-02 4.54E-01 organelle fission (GO:0048285) 290 12 28.67 - .42 1.07E-03 3.82E-02 protein localization to organelle (GO:0033365) 605 25 59.82 - .42 1.12E-06 1.09E-04 double-strand break repair (GO:0006302) 170 7 16.81 - .42 1.65E-02 3.04E-01 organelle localization by membrane tethering (GO:0140056) 73 3 7.22 - .42 1.57E-01 1.00E00 positive regulation of chromosome organization (GO:2001252) 171 7 16.91 - .41 1.67E-02 3.07E-01 internal protein amino acid acetylation (GO:0006475) 98 4 9.69 - .41 8.09E-02 8.07E-01 homologous chromosome segregation (GO:0045143) 49 2 4.84 - .41 3.22E-01 1.00E00 internal peptidyl-lysine acetylation (GO:0018393) 98 4 9.69 - .41 8.09E-02 8.07E-01 regulation of centrosome cycle (GO:0046605) 49 2 4.84 - .41 3.22E-01 1.00E00 regulation of chromosome organization (GO:0033044) 270 11 26.70 - .41 1.47E-03 4.95E-02 methylation (GO:0032259) 247 10 24.42 - .41 2.01E-03 6.21E-02 transcription, DNA-templated (GO:0006351) 272 11 26.89 - .41 1.51E-03 5.05E-02 nucleic acid-templated transcription (GO:0097659) 273 11 26.99 - .41 1.11E-03 3.95E-02 endoplasmic reticulum to Golgi vesicle-mediated transport (GO:0006888) 100 4 9.89 - .40 8.24E-02 8.17E-01 mitotic spindle assembly checkpoint signaling (GO:0007094) 25 1 2.47 - .40 7.26E-01 1.00E00 endosome organization (GO:0007032) 50 2 4.94 - .40 3.25E-01 1.00E00 regulation of protein sumoylation (GO:0033233) 25 1 2.47 - .40 7.26E-01 1.00E00 positive regulation of signal transduction by p53 class mediator (GO:1901798) 25 1 2.47 - .40 7.26E-01 1.00E00 mRNA splice site selection (GO:0006376) 25 1 2.47 - .40 7.26E-01 1.00E00 response to misfolded protein (GO:0051788) 25 1 2.47 - .40 7.26E-01 1.00E00 quinone metabolic process (GO:1901661) 25 1 2.47 - .40 7.26E-01 1.00E00 spindle assembly checkpoint signaling (GO:0071173) 25 1 2.47 - .40 7.26E-01 1.00E00 drug metabolic process (GO:0017144) 25 1 2.47 - .40 7.26E-01 1.00E00 nucleoside monophosphate biosynthetic process (GO:0009124) 25 1 2.47 - .40 7.26E-01 1.00E00 negative regulation of telomere maintenance via telomere lengthening (GO:1904357) 25 1 2.47 - .40 7.26E-01 1.00E00 respiratory chain complex IV assembly (GO:0008535) 25 1 2.47 - .40 7.26E-01 1.00E00 determination of adult lifespan (GO:0008340) 25 1 2.47 - .40 7.26E-01 1.00E00 sphingolipid catabolic process (GO:0030149) 25 1 2.47 - .40 7.26E-01 1.00E00 central nervous system projection neuron axonogenesis (GO:0021952) 25 1 2.47 - .40 7.26E-01 1.00E00 cell proliferation in forebrain (GO:0021846) 25 1 2.47 - .40 7.26E-01 1.00E00 peptidyl-lysine acetylation (GO:0018394) 101 4 9.99 - .40 6.01E-02 6.89E-01 RNA biosynthetic process (GO:0032774) 279 11 27.59 - .40 8.40E-04 3.14E-02 embryonic digit morphogenesis (GO:0042733) 51 2 5.04 - .40 2.33E-01 1.00E00 regulation of chromosome segregation (GO:0051983) 77 3 7.61 - .39 1.16E-01 9.46E-01 negative regulation of protein ubiquitination (GO:0031397) 77 3 7.61 - .39 1.16E-01 9.46E-01 macromolecule methylation (GO:0043414) 206 8 20.37 - .39 5.21E-03 1.30E-01 camera-type eye photoreceptor cell differentiation (GO:0060219) 26 1 2.57 - .39 5.09E-01 1.00E00 translational elongation (GO:0006414) 26 1 2.57 - .39 5.09E-01 1.00E00 protein K11-linked ubiquitination (GO:0070979) 26 1 2.57 - .39 5.09E-01 1.00E00 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (GO:1902175) 26 1 2.57 - .39 5.09E-01 1.00E00 alpha-amino acid metabolic process (GO:1901605) 130 5 12.85 - .39 3.26E-02 4.74E-01 histone H4 acetylation (GO:0043967) 52 2 5.14 - .39 2.33E-01 1.00E00 metaphase plate congression (GO:0051310) 52 2 5.14 - .39 2.33E-01 1.00E00 negative regulation of ERBB signaling pathway (GO:1901185) 26 1 2.57 - .39 5.09E-01 1.00E00 stem cell division (GO:0017145) 26 1 2.57 - .39 5.09E-01 1.00E00 regulation of mitochondrial translation (GO:0070129) 26 1 2.57 - .39 5.09E-01 1.00E00 aspartate family amino acid metabolic process (GO:0009066) 26 1 2.57 - .39 5.09E-01 1.00E00 positive regulation of lamellipodium assembly (GO:0010592) 26 1 2.57 - .39 5.09E-01 1.00E00 membrane docking (GO:0022406) 78 3 7.71 - .39 1.17E-01 9.49E-01 nuclear chromosome segregation (GO:0098813) 183 7 18.09 - .39 6.97E-03 1.64E-01 spermatid development (GO:0007286) 132 5 13.05 - .38 2.38E-02 3.88E-01 nucleocytoplasmic transport (GO:0006913) 185 7 18.29 - .38 7.11E-03 1.67E-01 nuclear transport (GO:0051169) 185 7 18.29 - .38 7.11E-03 1.67E-01 DNA metabolic process (GO:0006259) 583 22 57.64 - .38 2.22E-07 2.69E-05 protein localization to synapse (GO:0035418) 53 2 5.24 - .38 2.34E-01 1.00E00 cilium movement (GO:0003341) 106 4 10.48 - .38 4.47E-02 5.59E-01 ER-nucleus signaling pathway (GO:0006984) 27 1 2.67 - .37 5.10E-01 1.00E00 regulation of viral release from host cell (GO:1902186) 27 1 2.67 - .37 5.10E-01 1.00E00 protein palmitoylation (GO:0018345) 27 1 2.67 - .37 5.10E-01 1.00E00 mRNA polyadenylation (GO:0006378) 27 1 2.67 - .37 5.10E-01 1.00E00 cellular response to mechanical stimulus (GO:0071260) 27 1 2.67 - .37 5.10E-01 1.00E00 mitotic spindle checkpoint signaling (GO:0071174) 27 1 2.67 - .37 5.10E-01 1.00E00 acetyl-CoA metabolic process (GO:0006084) 27 1 2.67 - .37 5.10E-01 1.00E00 regulation of mRNA 3'-end processing (GO:0031440) 27 1 2.67 - .37 5.10E-01 1.00E00 embryonic eye morphogenesis (GO:0048048) 27 1 2.67 - .37 5.10E-01 1.00E00 non-canonical Wnt signaling pathway (GO:0035567) 27 1 2.67 - .37 5.10E-01 1.00E00 positive regulation of phosphatase activity (GO:0010922) 27 1 2.67 - .37 5.10E-01 1.00E00 production of miRNAs involved in gene silencing by miRNA (GO:0035196) 27 1 2.67 - .37 5.10E-01 1.00E00 isoprenoid biosynthetic process (GO:0008299) 27 1 2.67 - .37 5.10E-01 1.00E00 sensory perception of smell (GO:0007608) 108 4 10.68 - .37 4.50E-02 5.62E-01 regulation of protein polyubiquitination (GO:1902914) 27 1 2.67 - .37 5.10E-01 1.00E00 negative regulation of mitotic metaphase/anaphase transition (GO:0045841) 27 1 2.67 - .37 5.10E-01 1.00E00 purine nucleoside bisphosphate metabolic process (GO:0034032) 82 3 8.11 - .37 8.58E-02 8.33E-01 ribonucleoside bisphosphate metabolic process (GO:0033875) 82 3 8.11 - .37 8.58E-02 8.32E-01 nucleoside bisphosphate metabolic process (GO:0033865) 82 3 8.11 - .37 8.58E-02 8.32E-01 regulation of DNA biosynthetic process (GO:2000278) 110 4 10.88 - .37 4.61E-02 5.73E-01 microtubule cytoskeleton organization involved in mitosis (GO:1902850) 110 4 10.88 - .37 4.61E-02 5.72E-01 positive regulation of mRNA metabolic process (GO:1903313) 111 4 10.97 - .36 3.30E-02 4.78E-01 spermatid differentiation (GO:0048515) 139 5 13.74 - .36 1.80E-02 3.23E-01 nucleic acid metabolic process (GO:0090304) 1621 58 160.27 - .36 1.46E-20 1.17E-17 negative regulation of mitotic sister chromatid separation (GO:2000816) 28 1 2.77 - .36 5.13E-01 1.00E00 DNA biosynthetic process (GO:0071897) 56 2 5.54 - .36 1.69E-01 1.00E00 cell redox homeostasis (GO:0045454) 28 1 2.77 - .36 5.13E-01 1.00E00 reproductive behavior (GO:0019098) 28 1 2.77 - .36 5.13E-01 1.00E00 negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) 28 1 2.77 - .36 5.13E-01 1.00E00 negative regulation of mitotic sister chromatid segregation (GO:0033048) 28 1 2.77 - .36 5.13E-01 1.00E00 negative regulation of sister chromatid segregation (GO:0033046) 28 1 2.77 - .36 5.13E-01 1.00E00 protein hydroxylation (GO:0018126) 28 1 2.77 - .36 5.13E-01 1.00E00 regulation of histone H3-K4 methylation (GO:0051569) 28 1 2.77 - .36 5.13E-01 1.00E00 TOR signaling (GO:0031929) 28 1 2.77 - .36 5.13E-01 1.00E00 tricarboxylic acid cycle (GO:0006099) 28 1 2.77 - .36 5.13E-01 1.00E00 regulation of mitochondrial fission (GO:0090140) 28 1 2.77 - .36 5.13E-01 1.00E00 protein K63-linked deubiquitination (GO:0070536) 28 1 2.77 - .36 5.13E-01 1.00E00 RNA polyadenylation (GO:0043631) 28 1 2.77 - .36 5.13E-01 1.00E00 spindle checkpoint signaling (GO:0031577) 28 1 2.77 - .36 5.13E-01 1.00E00 histone lysine demethylation (GO:0070076) 28 1 2.77 - .36 5.13E-01 1.00E00 histone demethylation (GO:0016577) 28 1 2.77 - .36 5.13E-01 1.00E00 activation of MAPKK activity (GO:0000186) 28 1 2.77 - .36 5.13E-01 1.00E00 photoreceptor cell differentiation (GO:0046530) 56 2 5.54 - .36 1.69E-01 1.00E00 negative regulation of protein catabolic process (GO:0042177) 112 4 11.07 - .36 3.31E-02 4.79E-01 protein-DNA complex subunit organization (GO:0071824) 142 5 14.04 - .36 1.31E-02 2.58E-01 protein K48-linked ubiquitination (GO:0070936) 57 2 5.64 - .35 1.70E-01 1.00E00 regulation of cilium assembly (GO:1902017) 57 2 5.64 - .35 1.70E-01 1.00E00 vesicle docking (GO:0048278) 57 2 5.64 - .35 1.70E-01 1.00E00 ATP synthesis coupled electron transport (GO:0042773) 57 2 5.64 - .35 1.70E-01 1.00E00 signal transduction in response to DNA damage (GO:0042770) 115 4 11.37 - .35 3.43E-02 4.92E-01 stem cell population maintenance (GO:0019827) 115 4 11.37 - .35 3.43E-02 4.91E-01 cartilage development involved in endochondral bone morphogenesis (GO:0060351) 29 1 2.87 - .35 5.16E-01 1.00E00 myelination in peripheral nervous system (GO:0022011) 29 1 2.87 - .35 5.16E-01 1.00E00 production of small RNA involved in gene silencing by RNA (GO:0070918) 29 1 2.87 - .35 5.16E-01 1.00E00 negative regulation of chromosome separation (GO:1905819) 29 1 2.87 - .35 5.16E-01 1.00E00 dorsal/ventral pattern formation (GO:0009953) 58 2 5.73 - .35 1.71E-01 1.00E00 peripheral nervous system axon ensheathment (GO:0032292) 29 1 2.87 - .35 5.16E-01 1.00E00 chromosome organization involved in meiotic cell cycle (GO:0070192) 58 2 5.73 - .35 1.71E-01 1.00E00 dsRNA processing (GO:0031050) 29 1 2.87 - .35 5.16E-01 1.00E00 histone monoubiquitination (GO:0010390) 29 1 2.87 - .35 5.16E-01 1.00E00 camera-type eye morphogenesis (GO:0048593) 117 4 11.57 - .35 2.44E-02 3.91E-01 nucleosome organization (GO:0034728) 88 3 8.70 - .34 6.35E-02 7.08E-01 canonical Wnt signaling pathway (GO:0060070) 59 2 5.83 - .34 1.73E-01 9.70E-01 RNA metabolic process (GO:0016070) 1123 38 111.03 - .34 2.53E-15 9.83E-13 microtubule bundle formation (GO:0001578) 89 3 8.80 - .34 6.43E-02 7.14E-01 DNA damage checkpoint signaling (GO:0000077) 89 3 8.80 - .34 6.43E-02 7.14E-01 cerebellar Purkinje cell layer development (GO:0021680) 30 1 2.97 - .34 5.22E-01 1.00E00 chloride transmembrane transport (GO:1902476) 30 1 2.97 - .34 5.22E-01 1.00E00 negative regulation of chromosome segregation (GO:0051985) 30 1 2.97 - .34 5.22E-01 1.00E00 DNA-templated transcription, elongation (GO:0006354) 30 1 2.97 - .34 5.22E-01 1.00E00 histone H3-K4 methylation (GO:0051568) 30 1 2.97 - .34 5.22E-01 1.00E00 nucleotide-sugar metabolic process (GO:0009225) 30 1 2.97 - .34 5.22E-01 1.00E00 regulation of aerobic respiration (GO:1903715) 30 1 2.97 - .34 5.22E-01 1.00E00 ovulation cycle process (GO:0022602) 30 1 2.97 - .34 5.22E-01 1.00E00 peptide biosynthetic process (GO:0043043) 303 10 29.96 - .33 8.29E-05 4.48E-03 microtubule organizing center organization (GO:0031023) 91 3 9.00 - .33 4.59E-02 5.72E-01 RNA transport (GO:0050658) 122 4 12.06 - .33 1.80E-02 3.24E-01 nucleic acid transport (GO:0050657) 122 4 12.06 - .33 1.80E-02 3.23E-01 axoneme assembly (GO:0035082) 61 2 6.03 - .33 1.23E-01 9.84E-01 phosphatidylinositol 3-kinase signaling (GO:0014065) 31 1 3.07 - .33 3.59E-01 1.00E00 establishment of RNA localization (GO:0051236) 124 4 12.26 - .33 1.85E-02 3.29E-01 rRNA modification (GO:0000154) 31 1 3.07 - .33 3.59E-01 1.00E00 serine family amino acid metabolic process (GO:0009069) 31 1 3.07 - .33 3.59E-01 1.00E00 protein import (GO:0017038) 127 4 12.56 - .32 1.32E-02 2.59E-01 positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261) 32 1 3.16 - .32 3.61E-01 1.00E00 peroxisome organization (GO:0007031) 32 1 3.16 - .32 3.61E-01 1.00E00 protein transmembrane import into intracellular organelle (GO:0044743) 32 1 3.16 - .32 3.61E-01 1.00E00 protein demethylation (GO:0006482) 32 1 3.16 - .32 3.61E-01 1.00E00 Schwann cell development (GO:0014044) 32 1 3.16 - .32 3.61E-01 1.00E00 regulation of axon regeneration (GO:0048679) 32 1 3.16 - .32 3.61E-01 1.00E00 protein deubiquitination (GO:0016579) 96 3 9.49 - .32 3.34E-02 4.83E-01 acidic amino acid transport (GO:0015800) 32 1 3.16 - .32 3.61E-01 1.00E00 regulation of necrotic cell death (GO:0010939) 32 1 3.16 - .32 3.61E-01 1.00E00 regulation of protein export from nucleus (GO:0046825) 32 1 3.16 - .32 3.61E-01 1.00E00 protein localization to nucleus (GO:0034504) 160 5 15.82 - .32 3.82E-03 1.02E-01 protein dealkylation (GO:0008214) 32 1 3.16 - .32 3.61E-01 1.00E00 DNA repair (GO:0006281) 417 13 41.23 - .32 1.27E-06 1.23E-04 regulation of mRNA metabolic process (GO:1903311) 257 8 25.41 - .31 1.95E-04 9.20E-03 tRNA metabolic process (GO:0006399) 161 5 15.92 - .31 3.83E-03 1.02E-01 establishment of chromosome localization (GO:0051303) 65 2 6.43 - .31 8.83E-02 8.36E-01 regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0000079) 65 2 6.43 - .31 8.83E-02 8.35E-01 regulation of histone methylation (GO:0031060) 65 2 6.43 - .31 8.83E-02 8.35E-01 positive regulation of lamellipodium organization (GO:1902745) 33 1 3.26 - .31 3.63E-01 1.00E00 neural tube patterning (GO:0021532) 33 1 3.26 - .31 3.63E-01 1.00E00 detection of light stimulus (GO:0009583) 33 1 3.26 - .31 3.63E-01 1.00E00 fibroblast growth factor receptor signaling pathway (GO:0008543) 33 1 3.26 - .31 3.63E-01 1.00E00 negative regulation of DNA recombination (GO:0045910) 33 1 3.26 - .31 3.63E-01 1.00E00 cilium organization (GO:0044782) 268 8 26.50 - .30 7.42E-05 4.08E-03 chromosome localization (GO:0050000) 67 2 6.62 - .30 8.89E-02 8.39E-01 protein localization to chromosome (GO:0034502) 67 2 6.62 - .30 8.89E-02 8.38E-01 mRNA transport (GO:0051028) 101 3 9.99 - .30 2.42E-02 3.89E-01 cilium assembly (GO:0060271) 237 7 23.43 - .30 2.56E-04 1.18E-02 one-carbon metabolic process (GO:0006730) 34 1 3.36 - .30 3.67E-01 1.00E00 negative regulation of intracellular steroid hormone receptor signaling pathway (GO:0033144) 34 1 3.36 - .30 3.67E-01 1.00E00 double-strand break repair via nonhomologous end joining (GO:0006303) 34 1 3.36 - .30 3.67E-01 1.00E00 negative regulation of telomere maintenance (GO:0032205) 34 1 3.36 - .30 3.67E-01 1.00E00 positive regulation of mRNA processing (GO:0050685) 34 1 3.36 - .30 3.67E-01 1.00E00 cytochrome complex assembly (GO:0017004) 34 1 3.36 - .30 3.67E-01 1.00E00 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) 34 1 3.36 - .30 3.67E-01 1.00E00 replication fork processing (GO:0031297) 34 1 3.36 - .30 3.67E-01 1.00E00 positive regulation of smoothened signaling pathway (GO:0045880) 34 1 3.36 - .30 3.67E-01 1.00E00 chromosome segregation (GO:0007059) 239 7 23.63 - .30 1.80E-04 8.65E-03 steroid biosynthetic process (GO:0006694) 69 2 6.82 - .29 9.13E-02 8.51E-01 regulation of cyclin-dependent protein kinase activity (GO:1904029) 69 2 6.82 - .29 9.13E-02 8.51E-01 multicellular organism aging (GO:0010259) 35 1 3.46 - .29 2.53E-01 1.00E00 positive regulation of DNA biosynthetic process (GO:2000573) 70 2 6.92 - .29 6.33E-02 7.06E-01 base-excision repair (GO:0006284) 35 1 3.46 - .29 2.53E-01 1.00E00 fatty acid catabolic process (GO:0009062) 70 2 6.92 - .29 6.33E-02 7.06E-01 dendritic spine organization (GO:0097061) 35 1 3.46 - .29 2.53E-01 1.00E00 ubiquitin-dependent ERAD pathway (GO:0030433) 71 2 7.02 - .28 6.34E-02 7.07E-01 negative regulation of chromosome organization (GO:2001251) 72 2 7.12 - .28 6.39E-02 7.10E-01 positive regulation of double-strand break repair (GO:2000781) 36 1 3.56 - .28 2.53E-01 1.00E00 motile cilium assembly (GO:0044458) 36 1 3.56 - .28 2.53E-01 1.00E00 execution phase of apoptosis (GO:0097194) 36 1 3.56 - .28 2.53E-01 1.00E00 mRNA metabolic process (GO:0016071) 506 14 50.03 - .28 8.09E-09 1.27E-06 RNA localization (GO:0006403) 145 4 14.34 - .28 3.64E-03 9.98E-02 DNA-dependent DNA replication (GO:0006261) 109 3 10.78 - .28 1.26E-02 2.54E-01 ncRNA metabolic process (GO:0034660) 404 11 39.94 - .28 2.14E-07 2.66E-05 regulation of transcription initiation from RNA polymerase II promoter (GO:0060260) 37 1 3.66 - .27 2.54E-01 1.00E00 adherens junction organization (GO:0034332) 37 1 3.66 - .27 2.54E-01 1.00E00 protein-containing complex localization (GO:0031503) 188 5 18.59 - .27 5.55E-04 2.25E-02 positive regulation of DNA-templated transcription, initiation (GO:2000144) 38 1 3.76 - .27 2.56E-01 1.00E00 protein modification by small protein removal (GO:0070646) 114 3 11.27 - .27 9.01E-03 2.00E-01 DNA methylation (GO:0006306) 39 1 3.86 - .26 2.60E-01 1.00E00 DNA alkylation (GO:0006305) 39 1 3.86 - .26 2.60E-01 1.00E00 protein K63-linked ubiquitination (GO:0070534) 39 1 3.86 - .26 2.60E-01 1.00E00 histone ubiquitination (GO:0016574) 39 1 3.86 - .26 2.60E-01 1.00E00 platelet-derived growth factor receptor signaling pathway (GO:0048008) 39 1 3.86 - .26 2.60E-01 1.00E00 ATP-dependent chromatin remodeling (GO:0043044) 39 1 3.86 - .26 2.60E-01 1.00E00 regulation of double-strand break repair via homologous recombination (GO:0010569) 39 1 3.86 - .26 2.60E-01 1.00E00 respiratory gaseous exchange by respiratory system (GO:0007585) 39 1 3.86 - .26 2.60E-01 1.00E00 maintenance of protein localization in organelle (GO:0072595) 39 1 3.86 - .26 2.60E-01 1.00E00 vesicle docking involved in exocytosis (GO:0006904) 40 1 3.95 - .25 1.77E-01 9.88E-01 centrosome cycle (GO:0007098) 80 2 7.91 - .25 3.22E-02 4.69E-01 positive regulation of histone methylation (GO:0031062) 40 1 3.95 - .25 1.77E-01 9.88E-01 intracellular steroid hormone receptor signaling pathway (GO:0030518) 40 1 3.95 - .25 1.77E-01 9.87E-01 monocarboxylic acid catabolic process (GO:0072329) 81 2 8.01 - .25 3.24E-02 4.72E-01 translation (GO:0006412) 286 7 28.28 - .25 6.93E-06 5.60E-04 sulfur compound transport (GO:0072348) 41 1 4.05 - .25 1.77E-01 9.88E-01 DNA-dependent DNA replication maintenance of fidelity (GO:0045005) 41 1 4.05 - .25 1.77E-01 9.88E-01 mRNA 3'-end processing (GO:0031124) 41 1 4.05 - .25 1.77E-01 9.88E-01 RNA 3'-end processing (GO:0031123) 83 2 8.21 - .24 3.35E-02 4.83E-01 positive regulation of DNA replication (GO:0045740) 42 1 4.15 - .24 1.78E-01 9.94E-01 protein import into nucleus (GO:0006606) 84 2 8.31 - .24 2.28E-02 3.77E-01 DNA replication (GO:0006260) 169 4 16.71 - .24 6.99E-04 2.75E-02 ribonucleoprotein complex subunit organization (GO:0071826) 170 4 16.81 - .24 7.12E-04 2.78E-02 spindle assembly (GO:0051225) 86 2 8.50 - .24 2.31E-02 3.81E-01 spliceosomal complex assembly (GO:0000245) 43 1 4.25 - .24 1.80E-01 1.00E00 establishment or maintenance of apical/basal cell polarity (GO:0035088) 43 1 4.25 - .24 1.80E-01 1.00E00 establishment or maintenance of bipolar cell polarity (GO:0061245) 43 1 4.25 - .24 1.80E-01 1.00E00 mitochondrial respiratory chain complex assembly (GO:0033108) 87 2 8.60 - .23 2.35E-02 3.85E-01 ERAD pathway (GO:0036503) 87 2 8.60 - .23 2.35E-02 3.84E-01 regulation of DNA-templated transcription, initiation (GO:2000142) 44 1 4.35 - .23 1.84E-01 1.00E00 import into nucleus (GO:0051170) 88 2 8.70 - .23 2.40E-02 3.91E-01 inorganic anion transmembrane transport (GO:0098661) 45 1 4.45 - .22 1.23E-01 9.86E-01 regulation of RNA splicing (GO:0043484) 135 3 13.35 - .22 2.38E-03 7.18E-02 transmission of nerve impulse (GO:0019226) 46 1 4.55 - .22 1.24E-01 9.89E-01 mitotic spindle assembly (GO:0090307) 46 1 4.55 - .22 1.24E-01 9.89E-01 nucleotide-excision repair (GO:0006289) 47 1 4.65 - .22 1.25E-01 9.97E-01 microtubule polymerization or depolymerization (GO:0031109) 47 1 4.65 - .22 1.25E-01 9.97E-01 intraciliary transport (GO:0042073) 47 1 4.65 - .22 1.25E-01 9.96E-01 pyrimidine-containing compound metabolic process (GO:0072527) 47 1 4.65 - .22 1.25E-01 9.96E-01 regulation of DNA replication (GO:0006275) 96 2 9.49 - .21 1.17E-02 2.44E-01 regulation of telomere maintenance via telomerase (GO:0032210) 48 1 4.75 - .21 1.27E-01 9.55E-01 regulation of cellular respiration (GO:0043457) 48 1 4.75 - .21 1.27E-01 9.54E-01 mitotic nuclear division (GO:0140014) 146 3 14.44 - .21 8.23E-04 3.11E-02 fatty acid beta-oxidation (GO:0006635) 49 1 4.84 - .21 1.29E-01 9.73E-01 demethylation (GO:0070988) 49 1 4.84 - .21 1.29E-01 9.73E-01 negative regulation of ubiquitin-dependent protein catabolic process (GO:2000059) 50 1 4.94 - .20 8.56E-02 8.33E-01 regulation of postsynaptic membrane neurotransmitter receptor levels (GO:0099072) 50 1 4.94 - .20 8.56E-02 8.33E-01 regulation of alternative mRNA splicing, via spliceosome (GO:0000381) 50 1 4.94 - .20 8.56E-02 8.32E-01 neural retina development (GO:0003407) 50 1 4.94 - .20 8.56E-02 8.32E-01 mRNA splicing, via spliceosome (GO:0000398) 202 4 19.97 - .20 6.45E-05 3.65E-03 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) 202 4 19.97 - .20 6.45E-05 3.64E-03 RNA splicing, via transesterification reactions (GO:0000375) 202 4 19.97 - .20 6.45E-05 3.63E-03 DNA methylation or demethylation (GO:0044728) 51 1 5.04 - .20 8.61E-02 8.34E-01 rRNA metabolic process (GO:0016072) 205 4 20.27 - .20 4.42E-05 2.68E-03 RNA splicing (GO:0008380) 313 6 30.95 - .19 2.74E-07 3.25E-05 RNA processing (GO:0006396) 733 14 72.47 - .19 3.57E-16 1.64E-13 protein N-linked glycosylation (GO:0006487) 53 1 5.24 - .19 8.90E-02 8.38E-01 multicellular organism growth (GO:0035264) 106 2 10.48 - .19 5.90E-03 1.42E-01 ribonucleoprotein complex assembly (GO:0022618) 163 3 16.12 - .19 3.00E-04 1.33E-02 vesicle budding from membrane (GO:0006900) 55 1 5.44 - .18 5.94E-02 6.83E-01 mitochondrial ATP synthesis coupled electron transport (GO:0042775) 55 1 5.44 - .18 5.94E-02 6.83E-01 retina morphogenesis in camera-type eye (GO:0060042) 56 1 5.54 - .18 6.00E-02 6.88E-01 endocytic recycling (GO:0032456) 56 1 5.54 - .18 6.00E-02 6.88E-01 mRNA processing (GO:0006397) 393 7 38.86 - .18 2.48E-09 4.23E-07 ncRNA processing (GO:0034470) 339 6 33.52 - .18 3.15E-08 4.47E-06 non-motile cilium assembly (GO:1905515) 57 1 5.64 - .18 6.10E-02 6.91E-01 regulation of telomere maintenance via telomere lengthening (GO:1904356) 57 1 5.64 - .18 6.10E-02 6.90E-01 tRNA processing (GO:0008033) 114 2 11.27 - .18 2.82E-03 8.09E-02 sister chromatid segregation (GO:0000819) 120 2 11.86 - .17 1.33E-03 4.55E-02 cytoplasmic microtubule organization (GO:0031122) 61 1 6.03 - .17 4.18E-02 5.54E-01 negative regulation of proteolysis involved in cellular protein catabolic process (GO:1903051) 63 1 6.23 - .16 2.83E-02 4.40E-01 regulation of mRNA processing (GO:0050684) 128 2 12.66 - .16 9.64E-04 3.50E-02 ribonucleoprotein complex biogenesis (GO:0022613) 385 6 38.07 - .16 8.70E-10 1.61E-07 cytoplasmic translation (GO:0002181) 65 1 6.43 - .16 2.86E-02 4.43E-01 rRNA processing (GO:0006364) 197 3 19.48 - .15 1.62E-05 1.11E-03 regulation of intracellular steroid hormone receptor signaling pathway (GO:0033143) 67 1 6.62 - .15 2.99E-02 4.48E-01 RNA modification (GO:0009451) 137 2 13.55 - .15 4.65E-04 1.93E-02 spindle organization (GO:0007051) 141 2 13.94 - .14 3.18E-04 1.41E-02 telomere maintenance (GO:0000723) 71 1 7.02 - .14 2.03E-02 3.50E-01 telomere organization (GO:0032200) 71 1 7.02 - .14 2.03E-02 3.49E-01 negative regulation of cellular protein catabolic process (GO:1903363) 72 1 7.12 - .14 1.34E-02 2.62E-01 tRNA modification (GO:0006400) 75 1 7.42 - .13 1.38E-02 2.69E-01 regulation of telomere maintenance (GO:0032204) 79 1 7.81 - .13 9.37E-03 2.06E-01 mitotic spindle organization (GO:0007052) 83 1 8.21 - .12 6.37E-03 1.53E-01 regulation of mRNA splicing, via spliceosome (GO:0048024) 90 1 8.90 - .11 2.95E-03 8.42E-02 ribosome biogenesis (GO:0042254) 274 3 27.09 - .11 2.96E-08 4.24E-06 mitotic sister chromatid segregation (GO:0000070) 98 1 9.69 - .10 2.12E-03 6.50E-02 positive regulation of chronic inflammatory response (GO:0002678) 4 0 .40 - < 0.01 1.00E00 1.00E00 protein hexamerization (GO:0034214) 9 0 .89 - < 0.01 1.00E00 1.00E00 quinolinate catabolic process (GO:0034213) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of T cell anergy (GO:0002669) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of T cell tolerance induction (GO:0002666) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of B cell tolerance induction (GO:0002663) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to silver ion (GO:0010272) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of B cell tolerance induction (GO:0002661) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of peripheral tolerance induction (GO:0002660) 2 0 .20 - < 0.01 1.00E00 1.00E00 glycolipid translocation (GO:0034203) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to selenium ion (GO:0010269) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of peripheral tolerance induction (GO:0002658) 2 0 .20 - < 0.01 1.00E00 1.00E00 SCF complex assembly (GO:0010265) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of tolerance induction dependent upon immune response (GO:0002654) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of tolerance induction dependent upon immune response (GO:0002652) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of tolerance induction to self antigen (GO:0002651) 1 0 .10 - < 0.01 1.00E00 1.00E00 animal organ senescence (GO:0010260) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of chromatin assembly or disassembly (GO:0045799) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 negative regulation of chromatin assembly or disassembly (GO:0045798) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of intestinal cholesterol absorption (GO:0045797) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of cell volume (GO:0045795) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cell size (GO:0045793) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 negative regulation of cell size (GO:0045792) 10 0 .99 - < 0.01 1.00E00 1.00E00 regulation of tolerance induction to self antigen (GO:0002649) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of central tolerance induction (GO:0002648) 1 0 .10 - < 0.01 1.00E00 1.00E00 NADH dehydrogenase complex assembly (GO:0010257) 53 0 5.24 - < 0.01 1.34E-02 2.62E-01 regulation of central tolerance induction (GO:0002646) 1 0 .10 - < 0.01 1.00E00 1.00E00 glucose mediated signaling pathway (GO:0010255) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of tolerance induction (GO:0002645) 9 0 .89 - < 0.01 1.00E00 1.00E00 establishment or maintenance of transmembrane electrochemical gradient (GO:0010248) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of germinal center formation (GO:0002636) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of germinal center formation (GO:0002635) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of germinal center formation (GO:0002634) 10 0 .99 - < 0.01 1.00E00 1.00E00 negative regulation of granuloma formation (GO:0002632) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of granuloma formation (GO:0002631) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of asymmetric cell division (GO:0045770) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of T cell antigen processing and presentation (GO:0002626) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of T cell antigen processing and presentation (GO:0002625) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of asymmetric cell division (GO:0045769) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cellular amino acid metabolic process (GO:0045764) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of cellular amino acid metabolic process (GO:0045763) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of adenylate cyclase activity (GO:0045762) 8 0 .79 - < 0.01 1.00E00 1.00E00 response to UV-C (GO:0010225) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 negative regulation of Toll signaling pathway (GO:0045751) 2 0 .20 - < 0.01 1.00E00 1.00E00 maintenance of DNA methylation (GO:0010216) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway (GO:1903298) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of hypoxia-induced intrinsic apoptotic signaling pathway (GO:1903297) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of glutamate secretion, neurotransmission (GO:1903296) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of Notch signaling pathway (GO:0045746) 32 0 3.16 - < 0.01 1.12E-01 9.22E-01 regulation of glutamate secretion, neurotransmission (GO:1903294) 4 0 .40 - < 0.01 1.00E00 1.00E00 protein localization to Golgi membrane (GO:1903292) 3 0 .30 - < 0.01 1.00E00 1.00E00 arginine catabolic process to proline (GO:0019493) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0045737) 23 0 2.27 - < 0.01 2.61E-01 1.00E00 response to glucagon (GO:0033762) 5 0 .49 - < 0.01 1.00E00 1.00E00 forebrain dorsal/ventral pattern formation (GO:0021798) 4 0 .40 - < 0.01 1.00E00 1.00E00 chemorepulsion of branchiomotor axon (GO:0021793) 1 0 .10 - < 0.01 1.00E00 1.00E00 beta-alanine catabolic process (GO:0019484) 1 0 .10 - < 0.01 1.00E00 1.00E00 respiratory burst after phagocytosis (GO:0045728) 3 0 .30 - < 0.01 1.00E00 1.00E00 beta-alanine biosynthetic process (GO:0019483) 1 0 .10 - < 0.01 1.00E00 1.00E00 beta-alanine metabolic process (GO:0019482) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of integrin biosynthetic process (GO:0045726) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of cilium assembly (GO:0045724) 26 0 2.57 - < 0.01 1.65E-01 1.00E00 negative regulation of integrin biosynthetic process (GO:0045720) 1 0 .10 - < 0.01 1.00E00 1.00E00 ribosome localization (GO:0033750) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 postganglionic parasympathetic fiber development (GO:0021784) 1 0 .10 - < 0.01 1.00E00 1.00E00 L-lysine catabolic process (GO:0019477) 1 0 .10 - < 0.01 1.00E00 1.00E00 L-lysine catabolic process to acetyl-CoA (GO:0019474) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of fatty acid biosynthetic process (GO:0045717) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 4-hydroxyproline metabolic process (GO:0019471) 1 0 .10 - < 0.01 1.00E00 1.00E00 4-hydroxyproline catabolic process (GO:0019470) 1 0 .10 - < 0.01 1.00E00 1.00E00 lateral geniculate nucleus development (GO:0021771) 1 0 .10 - < 0.01 1.00E00 1.00E00 exon-exon junction complex disassembly (GO:1903259) 1 0 .10 - < 0.01 1.00E00 1.00E00 glycine decarboxylation via glycine cleavage system (GO:0019464) 3 0 .30 - < 0.01 1.00E00 1.00E00 multi-ciliated epithelial cell differentiation (GO:1903251) 7 0 .69 - < 0.01 1.00E00 1.00E00 posterior midgut development (GO:0007497) 1 0 .10 - < 0.01 1.00E00 1.00E00 midgut development (GO:0007494) 3 0 .30 - < 0.01 1.00E00 1.00E00 nucleus accumbens development (GO:0021768) 1 0 .10 - < 0.01 1.00E00 1.00E00 mammillary body development (GO:0021767) 1 0 .10 - < 0.01 1.00E00 1.00E00 amygdala development (GO:0021764) 4 0 .40 - < 0.01 1.00E00 1.00E00 subthalamic nucleus development (GO:0021763) 1 0 .10 - < 0.01 1.00E00 1.00E00 substantia nigra development (GO:0021762) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of citrulline biosynthetic process (GO:1903249) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of citrulline biosynthetic process (GO:1903248) 1 0 .10 - < 0.01 1.00E00 1.00E00 L-cysteine catabolic process to taurine (GO:0019452) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle hypertrophy in response to stress (GO:1903244) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac muscle hypertrophy in response to stress (GO:1903243) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle hypertrophy in response to stress (GO:1903242) 7 0 .69 - < 0.01 1.00E00 1.00E00 U2-type prespliceosome assembly (GO:1903241) 2 0 .20 - < 0.01 1.00E00 1.00E00 globus pallidus development (GO:0021759) 2 0 .20 - < 0.01 1.00E00 1.00E00 facial nucleus development (GO:0021754) 1 0 .10 - < 0.01 1.00E00 1.00E00 pronephric nephron tubule development (GO:0039020) 1 0 .10 - < 0.01 1.00E00 1.00E00 L-cysteine catabolic process to hypotaurine (GO:0019449) 1 0 .10 - < 0.01 1.00E00 1.00E00 L-cysteine catabolic process (GO:0019448) 3 0 .30 - < 0.01 1.00E00 1.00E00 vestibular nucleus development (GO:0021750) 2 0 .20 - < 0.01 1.00E00 1.00E00 tryptophan catabolic process to acetyl-CoA (GO:0019442) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of calcium ion-dependent exocytosis of neurotransmitter (GO:1903233) 3 0 .30 - < 0.01 1.00E00 1.00E00 pronephric nephron development (GO:0039019) 2 0 .20 - < 0.01 1.00E00 1.00E00 pattern specification involved in pronephros development (GO:0039017) 1 0 .10 - < 0.01 1.00E00 1.00E00 principal sensory nucleus of trigeminal nerve development (GO:0021740) 2 0 .20 - < 0.01 1.00E00 1.00E00 mesenchymal stem cell differentiation (GO:0072497) 2 0 .20 - < 0.01 1.00E00 1.00E00 DNA integration (GO:0015074) 3 0 .30 - < 0.01 1.00E00 1.00E00 pronephric nephron tubule morphogenesis (GO:0039008) 1 0 .10 - < 0.01 1.00E00 1.00E00 pronephric nephron morphogenesis (GO:0039007) 1 0 .10 - < 0.01 1.00E00 1.00E00 pronephric field specification (GO:0039003) 1 0 .10 - < 0.01 1.00E00 1.00E00 acetyl-CoA biosynthetic process from acetate (GO:0019427) 1 0 .10 - < 0.01 1.00E00 1.00E00 trigeminal sensory nucleus development (GO:0021730) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of protein processing involved in protein targeting to mitochondrion (GO:1903217) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein processing involved in protein targeting to mitochondrion (GO:1903216) 1 0 .10 - < 0.01 1.00E00 1.00E00 superior olivary nucleus maturation (GO:0021722) 1 0 .10 - < 0.01 1.00E00 1.00E00 sulfide oxidation (GO:0019418) 1 0 .10 - < 0.01 1.00E00 1.00E00 sulfur oxidation (GO:0019417) 2 0 .20 - < 0.01 1.00E00 1.00E00 acetate biosynthetic process (GO:0019413) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of L-dopa decarboxylase activity (GO:1903200) 1 0 .10 - < 0.01 1.00E00 1.00E00 hindgut morphogenesis (GO:0007442) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of systemic arterial blood pressure (GO:0003084) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 negative regulation of renal output by angiotensin (GO:0003083) 1 0 .10 - < 0.01 1.00E00 1.00E00 superior olivary nucleus development (GO:0021718) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of behavioral fear response (GO:2000987) 4 0 .40 - < 0.01 1.00E00 1.00E00 dolichol biosynthetic process (GO:0019408) 2 0 .20 - < 0.01 1.00E00 1.00E00 hexitol biosynthetic process (GO:0019406) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of ATP citrate synthase activity (GO:2000984) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of ATP citrate synthase activity (GO:2000983) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of inner ear receptor cell differentiation (GO:2000982) 1 0 .10 - < 0.01 1.00E00 1.00E00 galactitol metabolic process (GO:0019402) 1 0 .10 - < 0.01 1.00E00 1.00E00 alditol biosynthetic process (GO:0019401) 5 0 .49 - < 0.01 1.00E00 1.00E00 ectodermal digestive tract development (GO:0007439) 2 0 .20 - < 0.01 1.00E00 1.00E00 mesenchymal-epithelial cell signaling involved in lung development (GO:0060496) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell-cell signaling involved in lung development (GO:0060495) 2 0 .20 - < 0.01 1.00E00 1.00E00 lung induction (GO:0060492) 1 0 .10 - < 0.01 1.00E00 1.00E00 lateral sprouting involved in lung morphogenesis (GO:0060490) 2 0 .20 - < 0.01 1.00E00 1.00E00 renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure (GO:0003072) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by neurotransmitter (GO:0003070) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of forebrain neuron differentiation (GO:2000979) 1 0 .10 - < 0.01 1.00E00 1.00E00 cerebellar Purkinje cell differentiation (GO:0021702) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 positive regulation of pro-B cell differentiation (GO:2000975) 1 0 .10 - < 0.01 1.00E00 1.00E00 planar dichotomous subdivision of terminal units involved in lung branching morphogenesis (GO:0060489) 2 0 .20 - < 0.01 1.00E00 1.00E00 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis (GO:0060488) 2 0 .20 - < 0.01 1.00E00 1.00E00 club cell differentiation (GO:0060486) 3 0 .30 - < 0.01 1.00E00 1.00E00 lobar bronchus development (GO:0060482) 2 0 .20 - < 0.01 1.00E00 1.00E00 lobar bronchus epithelium development (GO:0060481) 2 0 .20 - < 0.01 1.00E00 1.00E00 acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure (GO:0003069) 1 0 .10 - < 0.01 1.00E00 1.00E00 lung goblet cell differentiation (GO:0060480) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by acetylcholine (GO:0003068) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of heart rate by epinephrine (GO:0003065) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of heart rate by acetylcholine (GO:0003063) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of heart rate by chemical signal (GO:0003062) 3 0 .30 - < 0.01 1.00E00 1.00E00 ventral midline development (GO:0007418) 3 0 .30 - < 0.01 1.00E00 1.00E00 acrosomal vesicle exocytosis (GO:0060478) 5 0 .49 - < 0.01 1.00E00 1.00E00 axon target recognition (GO:0007412) 2 0 .20 - < 0.01 1.00E00 1.00E00 cortical granule exocytosis (GO:0060471) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of vascular associated smooth muscle contraction (GO:0003056) 10 0 .99 - < 0.01 1.00E00 1.00E00 angiotensin-mediated drinking behavior (GO:0003051) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by atrial natriuretic peptide (GO:0003050) 2 0 .20 - < 0.01 1.00E00 1.00E00 prevention of polyspermy (GO:0060468) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of fertilization (GO:0060467) 3 0 .30 - < 0.01 1.00E00 1.00E00 heparan sulfate proteoglycan biosynthetic process, enzymatic modification (GO:0015015) 3 0 .30 - < 0.01 1.00E00 1.00E00 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process (GO:0015014) 6 0 .59 - < 0.01 1.00E00 1.00E00 pharynx development (GO:0060465) 2 0 .20 - < 0.01 1.00E00 1.00E00 glial cell fate determination (GO:0007403) 2 0 .20 - < 0.01 1.00E00 1.00E00 heparan sulfate proteoglycan biosynthetic process (GO:0015012) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 ganglion mother cell fate determination (GO:0007402) 1 0 .10 - < 0.01 1.00E00 1.00E00 right lung morphogenesis (GO:0060461) 1 0 .10 - < 0.01 1.00E00 1.00E00 left lung morphogenesis (GO:0060460) 2 0 .20 - < 0.01 1.00E00 1.00E00 acetaldehyde biosynthetic process (GO:0046186) 1 0 .10 - < 0.01 1.00E00 1.00E00 left lung development (GO:0060459) 2 0 .20 - < 0.01 1.00E00 1.00E00 right lung development (GO:0060458) 1 0 .10 - < 0.01 1.00E00 1.00E00 somatic sex determination (GO:0018993) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of gastric acid secretion (GO:0060455) 4 0 .40 - < 0.01 1.00E00 1.00E00 germ-line sex determination (GO:0018992) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of gastric acid secretion (GO:0060454) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of gastric acid secretion (GO:0060453) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of hindgut contraction (GO:0060450) 2 0 .20 - < 0.01 1.00E00 1.00E00 detection of oxygen (GO:0003032) 3 0 .30 - < 0.01 1.00E00 1.00E00 D-gluconate catabolic process (GO:0046177) 2 0 .20 - < 0.01 1.00E00 1.00E00 aldonic acid catabolic process (GO:0046176) 2 0 .20 - < 0.01 1.00E00 1.00E00 bud outgrowth involved in lung branching (GO:0060447) 3 0 .30 - < 0.01 1.00E00 1.00E00 mitochondrial large ribosomal subunit assembly (GO:1902775) 3 0 .30 - < 0.01 1.00E00 1.00E00 detection of hypoxic conditions in blood by carotid body chemoreceptor signaling (GO:0003029) 1 0 .10 - < 0.01 1.00E00 1.00E00 trachea formation (GO:0060440) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling (GO:0003027) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback (GO:0003026) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by baroreceptor feedback (GO:0003025) 5 0 .49 - < 0.01 1.00E00 1.00E00 glycerol-3-phosphate biosynthetic process (GO:0046167) 2 0 .20 - < 0.01 1.00E00 1.00E00 glyceraldehyde-3-phosphate biosynthetic process (GO:0046166) 2 0 .20 - < 0.01 1.00E00 1.00E00 heme a metabolic process (GO:0046160) 2 0 .20 - < 0.01 1.00E00 1.00E00 activation of protein kinase A activity (GO:0034199) 2 0 .20 - < 0.01 1.00E00 1.00E00 trachea morphogenesis (GO:0060439) 9 0 .89 - < 0.01 1.00E00 1.00E00 bronchiole morphogenesis (GO:0060436) 1 0 .10 - < 0.01 1.00E00 1.00E00 isoprenoid biosynthetic process via mevalonate (GO:1902767) 2 0 .20 - < 0.01 1.00E00 1.00E00 bronchus morphogenesis (GO:0060434) 2 0 .20 - < 0.01 1.00E00 1.00E00 bronchus development (GO:0060433) 7 0 .69 - < 0.01 1.00E00 1.00E00 lung pattern specification process (GO:0060432) 1 0 .10 - < 0.01 1.00E00 1.00E00 primary lung bud formation (GO:0060431) 2 0 .20 - < 0.01 1.00E00 1.00E00 lung saccule development (GO:0060430) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of chondrocyte development (GO:1902761) 1 0 .10 - < 0.01 1.00E00 1.00E00 lymph circulation (GO:0003017) 2 0 .20 - < 0.01 1.00E00 1.00E00 voluntary skeletal muscle contraction (GO:0003010) 2 0 .20 - < 0.01 1.00E00 1.00E00 mRNA methylation (GO:0080009) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 negative regulation of sterol import (GO:2000910) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of maintenance of mitotic sister chromatid cohesion (GO:0034184) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of maintenance of mitotic sister chromatid cohesion (GO:0034183) 3 0 .30 - < 0.01 1.00E00 1.00E00 lung connective tissue development (GO:0060427) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of maintenance of mitotic sister chromatid cohesion (GO:0034182) 7 0 .69 - < 0.01 1.00E00 1.00E00 nuclear pore organization (GO:0006999) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 cellular response to nitrogen starvation (GO:0006995) 9 0 .89 - < 0.01 1.00E00 1.00E00 positive regulation of lens fiber cell differentiation (GO:1902748) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to growth hormone (GO:0060416) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 imidazole-containing compound catabolic process (GO:0052805) 1 0 .10 - < 0.01 1.00E00 1.00E00 aorta smooth muscle tissue morphogenesis (GO:0060414) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of lamellipodium organization (GO:1902744) 6 0 .59 - < 0.01 1.00E00 1.00E00 ER overload response (GO:0006983) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 positive regulation of vitamin metabolic process (GO:0046136) 4 0 .40 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside catabolic process (GO:0046135) 5 0 .49 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside catabolic process (GO:0046133) 4 0 .40 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside metabolic process (GO:0046131) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of acetylcholine metabolic process (GO:0060409) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of acetylcholine metabolic process (GO:0060408) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of penile erection (GO:0060407) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of penile erection (GO:0060406) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of toll-like receptor 8 signaling pathway (GO:0034161) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of penile erection (GO:0060405) 8 0 .79 - < 0.01 1.00E00 1.00E00 axonemal microtubule depolymerization (GO:0060404) 1 0 .10 - < 0.01 1.00E00 1.00E00 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator (GO:0006978) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 negative regulation of chondrocyte proliferation (GO:1902731) 3 0 .30 - < 0.01 1.00E00 1.00E00 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:0006977) 10 0 .99 - < 0.01 1.00E00 1.00E00 DNA damage induced protein phosphorylation (GO:0006975) 6 0 .59 - < 0.01 1.00E00 1.00E00 hypotonic response (GO:0006971) 9 0 .89 - < 0.01 1.00E00 1.00E00 purine ribonucleoside biosynthetic process (GO:0046129) 9 0 .89 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside metabolic process (GO:0046125) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of toll-like receptor 8 signaling pathway (GO:0034159) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of proteoglycan biosynthetic process (GO:1902729) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of growth factor dependent skeletal muscle satellite cell proliferation (GO:1902728) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of toll-like receptor 6 signaling pathway (GO:0034151) 1 0 .10 - < 0.01 1.00E00 1.00E00 toll-like receptor 6 signaling pathway (GO:0034150) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of satellite cell differentiation (GO:1902725) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of skeletal muscle satellite cell proliferation (GO:1902724) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of skeletal muscle satellite cell proliferation (GO:1902723) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of prolactin secretion (GO:1902722) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of prolactin secretion (GO:1902721) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria (GO:0006965) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of antibacterial peptide biosynthetic process (GO:0006963) 1 0 .10 - < 0.01 1.00E00 1.00E00 guanosine catabolic process (GO:0046115) 1 0 .10 - < 0.01 1.00E00 1.00E00 nucleobase biosynthetic process (GO:0046112) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 xanthine biosynthetic process (GO:0046111) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of toll-like receptor 5 signaling pathway (GO:0034148) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of toll-like receptor 5 signaling pathway (GO:0034147) 1 0 .10 - < 0.01 1.00E00 1.00E00 toll-like receptor 5 signaling pathway (GO:0034146) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to spindle pole body (GO:0071988) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of toll-like receptor 3 signaling pathway (GO:0034141) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of toll-like receptor 3 signaling pathway (GO:0034140) 3 0 .30 - < 0.01 1.00E00 1.00E00 uridine metabolic process (GO:0046108) 2 0 .20 - < 0.01 1.00E00 1.00E00 thymidine metabolic process (GO:0046104) 2 0 .20 - < 0.01 1.00E00 1.00E00 inosine biosynthetic process (GO:0046103) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of antigen processing and presentation of peptide antigen via MHC class I (GO:0002591) 1 0 .10 - < 0.01 1.00E00 1.00E00 hypoxanthine biosynthetic process (GO:0046101) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of antigen processing and presentation of peptide antigen via MHC class I (GO:0002590) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of toll-like receptor 3 signaling pathway (GO:0034139) 9 0 .89 - < 0.01 1.00E00 1.00E00 nitrobenzene metabolic process (GO:0018916) 4 0 .40 - < 0.01 1.00E00 1.00E00 toll-like receptor 1 signaling pathway (GO:0034130) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of antigen processing and presentation of peptide antigen via MHC class I (GO:0002589) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of antigen processing and presentation of peptide antigen via MHC class II (GO:0002588) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of antigen processing and presentation of peptide antigen (GO:0002585) 3 0 .30 - < 0.01 1.00E00 1.00E00 response to ozone (GO:0010193) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II (GO:0002582) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of MyD88-independent toll-like receptor signaling pathway (GO:0034128) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of MyD88-independent toll-like receptor signaling pathway (GO:0034127) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitotic sister chromatid cohesion, centromeric (GO:0071962) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of cell adhesion involved in substrate-bound cell migration (GO:0006933) 3 0 .30 - < 0.01 1.00E00 1.00E00 substrate-dependent cell migration, cell attachment to substrate (GO:0006931) 3 0 .30 - < 0.01 1.00E00 1.00E00 vitamin E biosynthetic process (GO:0010189) 1 0 .10 - < 0.01 1.00E00 1.00E00 basophil chemotaxis (GO:0002575) 1 0 .10 - < 0.01 1.00E00 1.00E00 sugar mediated signaling pathway (GO:0010182) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of erythrocyte aggregation (GO:0034119) 1 0 .10 - < 0.01 1.00E00 1.00E00 recycling endosome to Golgi transport (GO:0071955) 2 0 .20 - < 0.01 1.00E00 1.00E00 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA (GO:0071951) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular component disassembly involved in execution phase of apoptosis (GO:0006921) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 somatic diversification of immune receptors via somatic mutation (GO:0002566) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 embryonic body morphogenesis (GO:0010172) 9 0 .89 - < 0.01 1.00E00 1.00E00 basophil degranulation (GO:0002561) 1 0 .10 - < 0.01 1.00E00 1.00E00 basophil mediated immunity (GO:0002560) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of erythrocyte clearance (GO:0034107) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of erythrocyte clearance (GO:0034106) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein deubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0071947) 4 0 .40 - < 0.01 1.00E00 1.00E00 nitrogen cycle metabolic process (GO:0071941) 7 0 .69 - < 0.01 1.00E00 1.00E00 histamine secretion by mast cell (GO:0002553) 5 0 .49 - < 0.01 1.00E00 1.00E00 serotonin secretion by mast cell (GO:0002552) 1 0 .10 - < 0.01 1.00E00 1.00E00 formation of animal organ boundary (GO:0010160) 1 0 .10 - < 0.01 1.00E00 1.00E00 thiamine transmembrane transport (GO:0071934) 2 0 .20 - < 0.01 1.00E00 1.00E00 replication fork reversal (GO:0071932) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0071931) 2 0 .20 - < 0.01 1.00E00 1.00E00 pinocytosis (GO:0006907) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 specification of animal organ position (GO:0010159) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to chlorate (GO:0010157) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of proton transport (GO:0010155) 24 0 2.37 - < 0.01 1.63E-01 1.00E00 activation of blood coagulation via clotting cascade (GO:0002543) 1 0 .10 - < 0.01 1.00E00 1.00E00 activation of plasma proteins involved in acute inflammatory response (GO:0002541) 1 0 .10 - < 0.01 1.00E00 1.00E00 alpha-tubulin acetylation (GO:0071929) 2 0 .20 - < 0.01 1.00E00 1.00E00 endocannabinoid signaling pathway (GO:0071926) 3 0 .30 - < 0.01 1.00E00 1.00E00 cohesin loading (GO:0071921) 2 0 .20 - < 0.01 1.00E00 1.00E00 prostaglandin production involved in inflammatory response (GO:0002539) 1 0 .10 - < 0.01 1.00E00 1.00E00 respiratory burst involved in inflammatory response (GO:0002536) 1 0 .10 - < 0.01 1.00E00 1.00E00 farnesyl diphosphate biosynthetic process, mevalonate pathway (GO:0010142) 2 0 .20 - < 0.01 1.00E00 1.00E00 G-quadruplex DNA formation (GO:0071919) 1 0 .10 - < 0.01 1.00E00 1.00E00 determination of liver left/right asymmetry (GO:0071910) 5 0 .49 - < 0.01 1.00E00 1.00E00 acute inflammatory response to non-antigenic stimulus (GO:0002525) 1 0 .10 - < 0.01 1.00E00 1.00E00 proline catabolic process to glutamate (GO:0010133) 2 0 .20 - < 0.01 1.00E00 1.00E00 determination of stomach left/right asymmetry (GO:0071909) 1 0 .10 - < 0.01 1.00E00 1.00E00 determination of intestine left/right asymmetry (GO:0071908) 1 0 .10 - < 0.01 1.00E00 1.00E00 determination of digestive tract left/right asymmetry (GO:0071907) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of neutrophil differentiation (GO:0045660) 2 0 .20 - < 0.01 1.00E00 1.00E00 neurofilament bundle assembly (GO:0033693) 1 0 .10 - < 0.01 1.00E00 1.00E00 natural killer cell tolerance induction (GO:0002519) 2 0 .20 - < 0.01 1.00E00 1.00E00 lymphocyte chemotaxis across high endothelial venule (GO:0002518) 1 0 .10 - < 0.01 1.00E00 1.00E00 T cell tolerance induction (GO:0002517) 2 0 .20 - < 0.01 1.00E00 1.00E00 phenylacetate catabolic process (GO:0010124) 3 0 .30 - < 0.01 1.00E00 1.00E00 B cell tolerance induction (GO:0002514) 1 0 .10 - < 0.01 1.00E00 1.00E00 arginine catabolic process to proline via ornithine (GO:0010121) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of luteinizing hormone secretion (GO:0033686) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of luteinizing hormone secretion (GO:0033685) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of luteinizing hormone secretion (GO:0033684) 2 0 .20 - < 0.01 1.00E00 1.00E00 nucleotide-excision repair, DNA incision (GO:0033683) 9 0 .89 - < 0.01 1.00E00 1.00E00 central tolerance induction to self antigen (GO:0002509) 1 0 .10 - < 0.01 1.00E00 1.00E00 central tolerance induction (GO:0002508) 2 0 .20 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of polysaccharide antigen via MHC class II (GO:0002505) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptide antigen assembly with MHC class II protein complex (GO:0002503) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptide antigen assembly with MHC class I protein complex (GO:0002502) 2 0 .20 - < 0.01 1.00E00 1.00E00 peptide antigen assembly with MHC protein complex (GO:0002501) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of L-dopa decarboxylase activity (GO:1903198) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of L-dopa biosynthetic process (GO:1903197) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of L-dopa biosynthetic process (GO:1903195) 1 0 .10 - < 0.01 1.00E00 1.00E00 glyoxal metabolic process (GO:1903189) 1 0 .10 - < 0.01 1.00E00 1.00E00 glucuronoside catabolic process (GO:0019391) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of mechanoreceptor differentiation (GO:0045633) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of SUMO transferase activity (GO:1903182) 1 0 .10 - < 0.01 1.00E00 1.00E00 cerebellar cortex maturation (GO:0021699) 2 0 .20 - < 0.01 1.00E00 1.00E00 cerebellar cortex structural organization (GO:0021698) 3 0 .30 - < 0.01 1.00E00 1.00E00 cerebellar Purkinje cell layer formation (GO:0021694) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 cerebellar Purkinje cell layer structural organization (GO:0021693) 2 0 .20 - < 0.01 1.00E00 1.00E00 glucuronoside metabolic process (GO:0019389) 3 0 .30 - < 0.01 1.00E00 1.00E00 cerebellar Purkinje cell layer morphogenesis (GO:0021692) 19 0 1.88 - < 0.01 4.08E-01 1.00E00 galactose catabolic process (GO:0019388) 5 0 .49 - < 0.01 1.00E00 1.00E00 cerebellar Purkinje cell layer maturation (GO:0021691) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of tyrosine 3-monooxygenase activity (GO:1903178) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of tyrosine 3-monooxygenase activity (GO:1903176) 1 0 .10 - < 0.01 1.00E00 1.00E00 fatty alcohol metabolic process (GO:1903173) 2 0 .20 - < 0.01 1.00E00 1.00E00 cerebellar molecular layer formation (GO:0021688) 1 0 .10 - < 0.01 1.00E00 1.00E00 cerebellar molecular layer morphogenesis (GO:0021687) 2 0 .20 - < 0.01 1.00E00 1.00E00 cerebellar granular layer structural organization (GO:0021685) 1 0 .10 - < 0.01 1.00E00 1.00E00 nerve maturation (GO:0021682) 1 0 .10 - < 0.01 1.00E00 1.00E00 galactolipid catabolic process (GO:0019376) 2 0 .20 - < 0.01 1.00E00 1.00E00 galactolipid biosynthetic process (GO:0019375) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of pyrroline-5-carboxylate reductase activity (GO:1903168) 1 0 .10 - < 0.01 1.00E00 1.00E00 galactolipid metabolic process (GO:0019374) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of pyrroline-5-carboxylate reductase activity (GO:1903167) 1 0 .10 - < 0.01 1.00E00 1.00E00 epoxygenase P450 pathway (GO:0019373) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of keratinocyte differentiation (GO:0045617) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular response to polycyclic arene (GO:1903166) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to polycyclic arene (GO:1903165) 1 0 .10 - < 0.01 1.00E00 1.00E00 cerebellar molecular layer development (GO:0021679) 3 0 .30 - < 0.01 1.00E00 1.00E00 lysobisphosphatidic acid metabolic process (GO:2001311) 2 0 .20 - < 0.01 1.00E00 1.00E00 fatty acid elongation, unsaturated fatty acid (GO:0019368) 7 0 .69 - < 0.01 1.00E00 1.00E00 fatty acid elongation, saturated fatty acid (GO:0019367) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of inner ear auditory receptor cell differentiation (GO:0045609) 1 0 .10 - < 0.01 1.00E00 1.00E00 ectoderm development (GO:0007398) 10 0 .99 - < 0.01 1.00E00 1.00E00 positive regulation of cell-cell adhesion mediated by integrin (GO:0033634) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of cell-cell adhesion mediated by integrin (GO:0033633) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of cell-cell adhesion mediated by integrin (GO:0033632) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 cell-cell adhesion mediated by integrin (GO:0033631) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of cell adhesion mediated by integrin (GO:0033630) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 lipoxin B4 biosynthetic process (GO:2001306) 1 0 .10 - < 0.01 1.00E00 1.00E00 lipoxin B4 metabolic process (GO:2001304) 1 0 .10 - < 0.01 1.00E00 1.00E00 rhombomere 5 formation (GO:0021666) 1 0 .10 - < 0.01 1.00E00 1.00E00 rhombomere 5 structural organization (GO:0021665) 1 0 .10 - < 0.01 1.00E00 1.00E00 rhombomere 5 morphogenesis (GO:0021664) 1 0 .10 - < 0.01 1.00E00 1.00E00 rhombomere 3 formation (GO:0021660) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of autophagy of mitochondrion (GO:1903147) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of autophagy of mitochondrion (GO:1903146) 23 0 2.27 - < 0.01 2.61E-01 1.00E00 positive regulation of establishment of endothelial barrier (GO:1903142) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of establishment of endothelial barrier (GO:1903141) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of cell adhesion mediated by integrin (GO:0033629) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of cell adhesion mediated by integrin (GO:0033628) 38 0 3.76 - < 0.01 4.56E-02 5.69E-01 positive regulation of integrin activation by cell surface receptor linked signal transduction (GO:0033626) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of integrin activation (GO:0033625) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of integrin activation (GO:0033624) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of integrin activation (GO:0033623) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 rhombomere 3 structural organization (GO:0021659) 1 0 .10 - < 0.01 1.00E00 1.00E00 rhombomere 3 morphogenesis (GO:0021658) 2 0 .20 - < 0.01 1.00E00 1.00E00 dolichol metabolic process (GO:0019348) 5 0 .49 - < 0.01 1.00E00 1.00E00 cysteine biosynthetic process (GO:0019344) 3 0 .30 - < 0.01 1.00E00 1.00E00 cysteine biosynthetic process via cystathionine (GO:0019343) 2 0 .20 - < 0.01 1.00E00 1.00E00 dibenzo-p-dioxin catabolic process (GO:0019341) 1 0 .10 - < 0.01 1.00E00 1.00E00 ventral midline determination (GO:0007371) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial proton-transporting ATP synthase complex assembly (GO:0033615) 6 0 .59 - < 0.01 1.00E00 1.00E00 vagus nerve morphogenesis (GO:0021644) 2 0 .20 - < 0.01 1.00E00 1.00E00 phenol-containing compound catabolic process (GO:0019336) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of centriole-centriole cohesion (GO:1903126) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of TRAIL-activated apoptotic signaling pathway (GO:1903122) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of TRAIL-activated apoptotic signaling pathway (GO:1903121) 4 0 .40 - < 0.01 1.00E00 1.00E00 oxalate metabolic process (GO:0033609) 1 0 .10 - < 0.01 1.00E00 1.00E00 chemokine receptor transport within lipid bilayer (GO:0033606) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of mammary gland epithelial cell proliferation (GO:0033600) 4 0 .40 - < 0.01 1.00E00 1.00E00 optic nerve structural organization (GO:0021633) 1 0 .10 - < 0.01 1.00E00 1.00E00 flavin adenine dinucleotide catabolic process (GO:0072389) 1 0 .10 - < 0.01 1.00E00 1.00E00 optic nerve morphogenesis (GO:0021631) 5 0 .49 - < 0.01 1.00E00 1.00E00 flavin adenine dinucleotide biosynthetic process (GO:0072388) 1 0 .10 - < 0.01 1.00E00 1.00E00 flavin adenine dinucleotide metabolic process (GO:0072387) 2 0 .20 - < 0.01 1.00E00 1.00E00 plus-end-directed organelle transport along microtubule (GO:0072386) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein localization to actin cytoskeleton (GO:1903119) 1 0 .10 - < 0.01 1.00E00 1.00E00 urate homeostasis (GO:1903118) 1 0 .10 - < 0.01 1.00E00 1.00E00 pentose catabolic process (GO:0019323) 3 0 .30 - < 0.01 1.00E00 1.00E00 plus-end-directed vesicle transport along microtubule (GO:0072383) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of actin filament-based movement (GO:1903116) 3 0 .30 - < 0.01 1.00E00 1.00E00 pentose biosynthetic process (GO:0019322) 2 0 .20 - < 0.01 1.00E00 1.00E00 pentose metabolic process (GO:0019321) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 hexose catabolic process (GO:0019320) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 zygotic specification of dorsal/ventral axis (GO:0007352) 2 0 .20 - < 0.01 1.00E00 1.00E00 olfactory nerve structural organization (GO:0021629) 1 0 .10 - < 0.01 1.00E00 1.00E00 olfactory nerve morphogenesis (GO:0021627) 1 0 .10 - < 0.01 1.00E00 1.00E00 oculomotor nerve formation (GO:0021623) 1 0 .10 - < 0.01 1.00E00 1.00E00 oculomotor nerve morphogenesis (GO:0021622) 1 0 .10 - < 0.01 1.00E00 1.00E00 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process (GO:1903100) 1 0 .10 - < 0.01 1.00E00 1.00E00 hypoglossal nerve morphogenesis (GO:0021618) 1 0 .10 - < 0.01 1.00E00 1.00E00 glossopharyngeal nerve morphogenesis (GO:0021615) 3 0 .30 - < 0.01 1.00E00 1.00E00 mannose catabolic process (GO:0019309) 1 0 .10 - < 0.01 1.00E00 1.00E00 D-ribose catabolic process (GO:0019303) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of dipeptide transport (GO:2000880) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of growth hormone receptor signaling pathway (GO:0060399) 3 0 .30 - < 0.01 1.00E00 1.00E00 growth hormone receptor signaling pathway via JAK-STAT (GO:0060397) 5 0 .49 - < 0.01 1.00E00 1.00E00 growth hormone receptor signaling pathway (GO:0060396) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 negative regulation of SMAD protein signal transduction (GO:0060392) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of oligopeptide transport (GO:2000878) 2 0 .20 - < 0.01 1.00E00 1.00E00 chromosome passenger complex localization to kinetochore (GO:0072356) 2 0 .20 - < 0.01 1.00E00 1.00E00 histone H3-T3 phosphorylation (GO:0072355) 2 0 .20 - < 0.01 1.00E00 1.00E00 synapse assembly involved in innervation (GO:0060386) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of DNA strand elongation (GO:0060383) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of DNA strand elongation (GO:0060382) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of single-stranded telomeric DNA binding (GO:0060381) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of single-stranded telomeric DNA binding (GO:0060380) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to anesthetic (GO:0072347) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of aldosterone secretion (GO:2000860) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of brood size (GO:0060378) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of mast cell differentiation (GO:0060377) 1 0 .10 - < 0.01 1.00E00 1.00E00 pole plasm assembly (GO:0007315) 3 0 .30 - < 0.01 1.00E00 1.00E00 oocyte anterior/posterior axis specification (GO:0007314) 3 0 .30 - < 0.01 1.00E00 1.00E00 mast cell differentiation (GO:0060374) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of ventricular cardiac muscle cell membrane depolarization (GO:0060373) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of atrial cardiac muscle cell membrane repolarization (GO:0060372) 2 0 .20 - < 0.01 1.00E00 1.00E00 susceptibility to T cell mediated cytotoxicity (GO:0060370) 1 0 .10 - < 0.01 1.00E00 1.00E00 guanine biosynthetic process (GO:0046099) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of mineralocorticoid secretion (GO:2000857) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular lactam metabolic process (GO:0072338) 2 0 .20 - < 0.01 1.00E00 1.00E00 deoxycytidine metabolic process (GO:0046092) 2 0 .20 - < 0.01 1.00E00 1.00E00 UDP-galactose transmembrane transport (GO:0072334) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of glucocorticoid secretion (GO:2000850) 3 0 .30 - < 0.01 1.00E00 1.00E00 oocyte axis specification (GO:0007309) 3 0 .30 - < 0.01 1.00E00 1.00E00 oocyte construction (GO:0007308) 3 0 .30 - < 0.01 1.00E00 1.00E00 sagittal suture morphogenesis (GO:0060367) 1 0 .10 - < 0.01 1.00E00 1.00E00 lambdoid suture morphogenesis (GO:0060366) 1 0 .10 - < 0.01 1.00E00 1.00E00 frontal suture morphogenesis (GO:0060364) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of NAD metabolic process (GO:1902690) 1 0 .10 - < 0.01 1.00E00 1.00E00 cytidine metabolic process (GO:0046087) 2 0 .20 - < 0.01 1.00E00 1.00E00 adenosine biosynthetic process (GO:0046086) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of corticosteroid hormone secretion (GO:2000847) 3 0 .30 - < 0.01 1.00E00 1.00E00 adenine biosynthetic process (GO:0046084) 3 0 .30 - < 0.01 1.00E00 1.00E00 adenine metabolic process (GO:0046083) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of testosterone secretion (GO:2000844) 1 0 .10 - < 0.01 1.00E00 1.00E00 dUTP catabolic process (GO:0046081) 1 0 .10 - < 0.01 1.00E00 1.00E00 dUTP metabolic process (GO:0046080) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to ammonium ion (GO:0060359) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of NAD metabolic process (GO:1902689) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of NAD metabolic process (GO:1902688) 3 0 .30 - < 0.01 1.00E00 1.00E00 dibenzo-p-dioxin metabolic process (GO:0018894) 1 0 .10 - < 0.01 1.00E00 1.00E00 inositol phosphorylation (GO:0052746) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of cell adhesion molecule production (GO:0060355) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of receptor localization to synapse (GO:1902684) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell adhesion molecule production (GO:0060352) 3 0 .30 - < 0.01 1.00E00 1.00E00 dUMP catabolic process (GO:0046079) 4 0 .40 - < 0.01 1.00E00 1.00E00 dUMP metabolic process (GO:0046078) 6 0 .59 - < 0.01 1.00E00 1.00E00 dUDP metabolic process (GO:0046077) 3 0 .30 - < 0.01 1.00E00 1.00E00 dTTP metabolic process (GO:0046075) 3 0 .30 - < 0.01 1.00E00 1.00E00 vesicle uncoating (GO:0072319) 8 0 .79 - < 0.01 1.00E00 1.00E00 dTMP catabolic process (GO:0046074) 3 0 .30 - < 0.01 1.00E00 1.00E00 clathrin coat disassembly (GO:0072318) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of androgen secretion (GO:2000836) 1 0 .10 - < 0.01 1.00E00 1.00E00 dTMP metabolic process (GO:0046073) 6 0 .59 - < 0.01 1.00E00 1.00E00 dTDP metabolic process (GO:0046072) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of androgen secretion (GO:2000834) 1 0 .10 - < 0.01 1.00E00 1.00E00 dGTP metabolic process (GO:0046070) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of steroid hormone secretion (GO:2000832) 3 0 .30 - < 0.01 1.00E00 1.00E00 metanephric glomerular epithelial cell development (GO:0072313) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric glomerular epithelial cell differentiation (GO:0072312) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of parathyroid hormone secretion (GO:2000830) 1 0 .10 - < 0.01 1.00E00 1.00E00 glomerular epithelial cell development (GO:0072310) 7 0 .69 - < 0.01 1.00E00 1.00E00 bone trabecula formation (GO:0060346) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of type I interferon-mediated signaling pathway (GO:0060340) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 cGMP catabolic process (GO:0046069) 3 0 .30 - < 0.01 1.00E00 1.00E00 cGMP metabolic process (GO:0046068) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 dGDP catabolic process (GO:0046067) 1 0 .10 - < 0.01 1.00E00 1.00E00 dGDP metabolic process (GO:0046066) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of parathyroid hormone secretion (GO:2000828) 2 0 .20 - < 0.01 1.00E00 1.00E00 dCTP metabolic process (GO:0046065) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial RNA surveillance (GO:2000827) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of heart morphogenesis (GO:2000826) 7 0 .69 - < 0.01 1.00E00 1.00E00 dCMP metabolic process (GO:0046063) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of androgen receptor activity (GO:2000825) 3 0 .30 - < 0.01 1.00E00 1.00E00 dCDP metabolic process (GO:0046062) 1 0 .10 - < 0.01 1.00E00 1.00E00 dATP catabolic process (GO:0046061) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis (GO:0072305) 1 0 .10 - < 0.01 1.00E00 1.00E00 dATP metabolic process (GO:0046060) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis (GO:0072304) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation (GO:2000820) 3 0 .30 - < 0.01 1.00E00 1.00E00 biphenyl metabolic process (GO:0018879) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of axon guidance (GO:1902668) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of maintenance of sister chromatid cohesion (GO:0034093) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of maintenance of sister chromatid cohesion (GO:0034092) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of maintenance of sister chromatid cohesion (GO:0034091) 7 0 .69 - < 0.01 1.00E00 1.00E00 interferon-gamma-mediated signaling pathway (GO:0060333) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of glucose mediated signaling pathway (GO:1902661) 3 0 .30 - < 0.01 1.00E00 1.00E00 cAMP metabolic process (GO:0046058) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 dADP catabolic process (GO:0046057) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of nucleotide-excision repair (GO:2000819) 4 0 .40 - < 0.01 1.00E00 1.00E00 dADP metabolic process (GO:0046056) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of mRNA stability involved in response to oxidative stress (GO:2000815) 2 0 .20 - < 0.01 1.00E00 1.00E00 UTP catabolic process (GO:0046052) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of barbed-end actin filament capping (GO:2000814) 2 0 .20 - < 0.01 1.00E00 1.00E00 UTP metabolic process (GO:0046051) 10 0 .99 - < 0.01 1.00E00 1.00E00 negative regulation of barbed-end actin filament capping (GO:2000813) 2 0 .20 - < 0.01 1.00E00 1.00E00 UMP catabolic process (GO:0046050) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of barbed-end actin filament capping (GO:2000812) 6 0 .59 - < 0.01 1.00E00 1.00E00 establishment of mitotic sister chromatid cohesion (GO:0034087) 2 0 .20 - < 0.01 1.00E00 1.00E00 establishment of sister chromatid cohesion (GO:0034085) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of glucose mediated signaling pathway (GO:1902659) 3 0 .30 - < 0.01 1.00E00 1.00E00 cytoplasmic actin-based contraction involved in cell motility (GO:0060327) 3 0 .30 - < 0.01 1.00E00 1.00E00 CENP-A containing nucleosome assembly (GO:0034080) 6 0 .59 - < 0.01 1.00E00 1.00E00 secondary alcohol biosynthetic process (GO:1902653) 29 0 2.87 - < 0.01 1.06E-01 8.97E-01 Golgi to vacuole transport (GO:0006896) 20 0 1.98 - < 0.01 2.51E-01 1.00E00 intra-Golgi vesicle-mediated transport (GO:0006891) 26 0 2.57 - < 0.01 1.65E-01 1.00E00 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum (GO:0006890) 43 0 4.25 - < 0.01 3.01E-02 4.49E-01 UMP metabolic process (GO:0046049) 5 0 .49 - < 0.01 1.00E00 1.00E00 UDP metabolic process (GO:0046048) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of synaptic vesicle clustering (GO:2000808) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled (GO:2000806) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled (GO:2000805) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of termination of RNA polymerase II transcription, poly(A)-coupled (GO:2000804) 3 0 .30 - < 0.01 1.00E00 1.00E00 ITP metabolic process (GO:0046041) 2 0 .20 - < 0.01 1.00E00 1.00E00 primitive erythrocyte differentiation (GO:0060319) 3 0 .30 - < 0.01 1.00E00 1.00E00 definitive erythrocyte differentiation (GO:0060318) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) 5 0 .49 - < 0.01 1.00E00 1.00E00 tertiary alcohol biosynthetic process (GO:1902645) 1 0 .10 - < 0.01 1.00E00 1.00E00 tertiary alcohol metabolic process (GO:1902644) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of elastin catabolic process (GO:0060311) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of elastin catabolic process (GO:0060310) 1 0 .10 - < 0.01 1.00E00 1.00E00 intracellular sequestering of iron ion (GO:0006880) 2 0 .20 - < 0.01 1.00E00 1.00E00 CTP metabolic process (GO:0046036) 9 0 .89 - < 0.01 1.00E00 1.00E00 CMP metabolic process (GO:0046035) 2 0 .20 - < 0.01 1.00E00 1.00E00 NAD-cap decapping (GO:0110155) 2 0 .20 - < 0.01 1.00E00 1.00E00 stress granule assembly (GO:0034063) 21 0 2.08 - < 0.01 2.52E-01 1.00E00 regulation of cell diameter (GO:0060305) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of phosphatidylinositol dephosphorylation (GO:0060304) 5 0 .49 - < 0.01 1.00E00 1.00E00 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (GO:1902635) 3 0 .30 - < 0.01 1.00E00 1.00E00 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process (GO:1902633) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of membrane hyperpolarization (GO:1902632) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of membrane hyperpolarization (GO:1902631) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of membrane hyperpolarization (GO:1902630) 5 0 .49 - < 0.01 1.00E00 1.00E00 response to anoxia (GO:0034059) 1 0 .10 - < 0.01 1.00E00 1.00E00 endosomal vesicle fusion (GO:0034058) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of mRNA stability involved in cellular response to UV (GO:1902629) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone H2B conserved C-terminal lysine ubiquitination (GO:0071894) 1 0 .10 - < 0.01 1.00E00 1.00E00 BMP signaling pathway involved in nephric duct formation (GO:0071893) 1 0 .10 - < 0.01 1.00E00 1.00E00 assembly of large subunit precursor of preribosome (GO:1902626) 3 0 .30 - < 0.01 1.00E00 1.00E00 programmed cell death induced by symbiont (GO:0034050) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of neutrophil migration (GO:1902623) 4 0 .40 - < 0.01 1.00E00 1.00E00 pyrimidine nucleotide transport (GO:0006864) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of transcription by glucose (GO:0046016) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of transcription by glucose (GO:0046015) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of T cell homeostatic proliferation (GO:0046014) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of T cell homeostatic proliferation (GO:0046013) 3 0 .30 - < 0.01 1.00E00 1.00E00 macrophage apoptotic process (GO:0071888) 1 0 .10 - < 0.01 1.00E00 1.00E00 Norrin signaling pathway (GO:0110135) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular response to fluoride (GO:1902618) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to fluoride (GO:1902617) 2 0 .20 - < 0.01 1.00E00 1.00E00 phospholipase C-activating adrenergic receptor signaling pathway (GO:0071882) 1 0 .10 - < 0.01 1.00E00 1.00E00 adenylate cyclase-inhibiting adrenergic receptor signaling pathway (GO:0071881) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of anti-Mullerian hormone signaling pathway (GO:1902613) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of anti-Mullerian hormone signaling pathway (GO:1902612) 1 0 .10 - < 0.01 1.00E00 1.00E00 extracellular transport (GO:0006858) 31 0 3.07 - < 0.01 1.09E-01 9.09E-01 mitochondrial pyruvate transmembrane transport (GO:0006850) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of circadian sleep/wake cycle, REM sleep (GO:0046005) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway (GO:0071879) 2 0 .20 - < 0.01 1.00E00 1.00E00 purine ribonucleoside bisphosphate biosynthetic process (GO:0034036) 2 0 .20 - < 0.01 1.00E00 1.00E00 purine ribonucleoside bisphosphate metabolic process (GO:0034035) 4 0 .40 - < 0.01 1.00E00 1.00E00 purine nucleoside bisphosphate catabolic process (GO:0034034) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of large conductance calcium-activated potassium channel activity (GO:1902608) 2 0 .20 - < 0.01 1.00E00 1.00E00 purine nucleoside bisphosphate biosynthetic process (GO:0034033) 30 0 2.97 - < 0.01 1.07E-01 9.01E-01 negative regulation of large conductance calcium-activated potassium channel activity (GO:1902607) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of large conductance calcium-activated potassium channel activity (GO:1902606) 3 0 .30 - < 0.01 1.00E00 1.00E00 ribonucleoside bisphosphate catabolic process (GO:0034031) 6 0 .59 - < 0.01 1.00E00 1.00E00 heterotrimeric G-protein complex assembly (GO:1902605) 1 0 .10 - < 0.01 1.00E00 1.00E00 ribonucleoside bisphosphate biosynthetic process (GO:0034030) 30 0 2.97 - < 0.01 1.07E-01 9.00E-01 carnitine transmembrane transport (GO:1902603) 2 0 .20 - < 0.01 1.00E00 1.00E00 pyruvate transport (GO:0006848) 4 0 .40 - < 0.01 1.00E00 1.00E00 acyl carnitine transport (GO:0006844) 4 0 .40 - < 0.01 1.00E00 1.00E00 mitochondrial citrate transmembrane transport (GO:0006843) 1 0 .10 - < 0.01 1.00E00 1.00E00 tricarboxylic acid transport (GO:0006842) 4 0 .40 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent (GO:0002489) 2 0 .20 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway (GO:0002488) 2 0 .20 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent (GO:0002485) 3 0 .30 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent (GO:0002481) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of lipid transporter activity (GO:0110114) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of lipid transporter activity (GO:0110113) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of lipid transporter activity (GO:0110112) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of animal organ morphogenesis (GO:0110111) 2 0 .20 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:0002479) 2 0 .20 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of exogenous peptide antigen via MHC class Ib (GO:0002477) 4 0 .40 - < 0.01 1.00E00 1.00E00 mRNA alternative polyadenylation (GO:0110104) 5 0 .49 - < 0.01 1.00E00 1.00E00 response to triglyceride (GO:0034014) 1 0 .10 - < 0.01 1.00E00 1.00E00 cobalt ion transport (GO:0006824) 6 0 .59 - < 0.01 1.00E00 1.00E00 germinal center formation (GO:0002467) 7 0 .69 - < 0.01 1.00E00 1.00E00 peripheral tolerance induction (GO:0002465) 2 0 .20 - < 0.01 1.00E00 1.00E00 tolerance induction to nonself antigen (GO:0002462) 1 0 .10 - < 0.01 1.00E00 1.00E00 tolerance induction dependent upon immune response (GO:0002461) 3 0 .30 - < 0.01 1.00E00 1.00E00 zygote asymmetric cell division (GO:0010070) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling (GO:0071848) 2 0 .20 - < 0.01 1.00E00 1.00E00 TNFSF11-mediated signaling pathway (GO:0071847) 5 0 .49 - < 0.01 1.00E00 1.00E00 actin filament debranching (GO:0071846) 2 0 .20 - < 0.01 1.00E00 1.00E00 phosphate ion transport (GO:0006817) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 peripheral T cell tolerance induction (GO:0002458) 1 0 .10 - < 0.01 1.00E00 1.00E00 peripheral B cell tolerance induction (GO:0002451) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell proliferation in bone marrow (GO:0071838) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of regulatory T cell differentiation (GO:0045590) 7 0 .69 - < 0.01 1.00E00 1.00E00 intermediate-density lipoprotein particle clearance (GO:0071831) 1 0 .10 - < 0.01 1.00E00 1.00E00 nitric oxide biosynthetic process (GO:0006809) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 interkinetic nuclear migration (GO:0022027) 9 0 .89 - < 0.01 1.00E00 1.00E00 malonyl-CoA biosynthetic process (GO:2001295) 1 0 .10 - < 0.01 1.00E00 1.00E00 malonyl-CoA catabolic process (GO:2001294) 1 0 .10 - < 0.01 1.00E00 1.00E00 malonyl-CoA metabolic process (GO:2001293) 2 0 .20 - < 0.01 1.00E00 1.00E00 eosinophil mediated immunity (GO:0002447) 2 0 .20 - < 0.01 1.00E00 1.00E00 histamine secretion involved in inflammatory response (GO:0002441) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of cytotoxic T cell differentiation (GO:0045585) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of cytotoxic T cell differentiation (GO:0045583) 3 0 .30 - < 0.01 1.00E00 1.00E00 lateral ganglionic eminence cell proliferation (GO:0022018) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of caveolin-mediated endocytosis (GO:2001287) 2 0 .20 - < 0.01 1.00E00 1.00E00 subpallium cell proliferation in forebrain (GO:0022012) 1 0 .10 - < 0.01 1.00E00 1.00E00 chronic inflammatory response to antigenic stimulus (GO:0002439) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to mycotoxin (GO:0010046) 3 0 .30 - < 0.01 1.00E00 1.00E00 response to iron(III) ion (GO:0010041) 2 0 .20 - < 0.01 1.00E00 1.00E00 tail-anchored membrane protein insertion into ER membrane (GO:0071816) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 positive regulation of fever generation by positive regulation of prostaglandin secretion (GO:0071812) 2 0 .20 - < 0.01 1.00E00 1.00E00 central nervous system vasculogenesis (GO:0022009) 3 0 .30 - < 0.01 1.00E00 1.00E00 convergent extension involved in neural plate elongation (GO:0022007) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis (GO:2001272) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis (GO:2001271) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis (GO:2001270) 5 0 .49 - < 0.01 1.00E00 1.00E00 immunoglobulin production in mucosal tissue (GO:0002426) 1 0 .10 - < 0.01 1.00E00 1.00E00 meiotic chromosome condensation (GO:0010032) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of podosome assembly (GO:0071802) 1 0 .10 - < 0.01 1.00E00 1.00E00 podosome assembly (GO:0071800) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of semaphorin-plexin signaling pathway (GO:2001262) 1 0 .10 - < 0.01 1.00E00 1.00E00 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor (GO:0002415) 1 0 .10 - < 0.01 1.00E00 1.00E00 immunoglobulin transcytosis in epithelial cells (GO:0002414) 2 0 .20 - < 0.01 1.00E00 1.00E00 plasmacytoid dendritic cell chemotaxis (GO:0002410) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of histone H3-K36 trimethylation (GO:2001255) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of histone H3-K36 trimethylation (GO:2001253) 3 0 .30 - < 0.01 1.00E00 1.00E00 red or far-red light signaling pathway (GO:0010017) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to meiotic spindle midzone (GO:1903096) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of protein K48-linked deubiquitination (GO:1903094) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of protein K48-linked deubiquitination (GO:1903093) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of cholesterol biosynthetic process (GO:0045541) 5 0 .49 - < 0.01 1.00E00 1.00E00 protein glycosylation in Golgi (GO:0033578) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein glycosylation in endoplasmic reticulum (GO:0033577) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of phosphatidylcholine biosynthetic process (GO:2001247) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein localization to condensed chromosome (GO:1903083) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 siderophore biosynthetic process (GO:0019290) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of C-C chemokine receptor CCR7 signaling pathway (GO:1903082) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of C-C chemokine receptor CCR7 signaling pathway (GO:1903080) 1 0 .10 - < 0.01 1.00E00 1.00E00 DNA replication, Okazaki fragment processing (GO:0033567) 2 0 .20 - < 0.01 1.00E00 1.00E00 gamma-tubulin complex localization (GO:0033566) 3 0 .30 - < 0.01 1.00E00 1.00E00 anterior/posterior axon guidance (GO:0033564) 3 0 .30 - < 0.01 1.00E00 1.00E00 dorsal/ventral axon guidance (GO:0033563) 2 0 .20 - < 0.01 1.00E00 1.00E00 abducens nerve formation (GO:0021599) 2 0 .20 - < 0.01 1.00E00 1.00E00 abducens nerve morphogenesis (GO:0021598) 2 0 .20 - < 0.01 1.00E00 1.00E00 rhombomere structural organization (GO:0021595) 1 0 .10 - < 0.01 1.00E00 1.00E00 rhombomere formation (GO:0021594) 1 0 .10 - < 0.01 1.00E00 1.00E00 rhombomere morphogenesis (GO:0021593) 3 0 .30 - < 0.01 1.00E00 1.00E00 isopentenyl diphosphate biosynthetic process, mevalonate pathway (GO:0019287) 3 0 .30 - < 0.01 1.00E00 1.00E00 cerebellum maturation (GO:0021590) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of death-inducing signaling complex assembly (GO:1903073) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of death-inducing signaling complex assembly (GO:1903072) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of ER-associated ubiquitin-dependent protein catabolic process (GO:1903071) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of ER-associated ubiquitin-dependent protein catabolic process (GO:1903070) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of response to gamma radiation (GO:2001229) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of response to gamma radiation (GO:2001228) 2 0 .20 - < 0.01 1.00E00 1.00E00 cerebellum structural organization (GO:0021589) 1 0 .10 - < 0.01 1.00E00 1.00E00 pons maturation (GO:0021586) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of ER-associated ubiquitin-dependent protein catabolic process (GO:1903069) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of reverse cholesterol transport (GO:1903064) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of reverse cholesterol transport (GO:1903062) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of protein lipidation (GO:1903061) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of protein lipidation (GO:1903060) 1 0 .10 - < 0.01 1.00E00 1.00E00 fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) 4 0 .40 - < 0.01 1.00E00 1.00E00 hindbrain maturation (GO:0021578) 4 0 .40 - < 0.01 1.00E00 1.00E00 hindbrain structural organization (GO:0021577) 1 0 .10 - < 0.01 1.00E00 1.00E00 rhombomere 6 development (GO:0021572) 1 0 .10 - < 0.01 1.00E00 1.00E00 rhombomere 5 development (GO:0021571) 3 0 .30 - < 0.01 1.00E00 1.00E00 rhombomere 4 development (GO:0021570) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of protein lipidation (GO:1903059) 6 0 .59 - < 0.01 1.00E00 1.00E00 glycine biosynthetic process, by transamination of glyoxylate (GO:0019265) 1 0 .10 - < 0.01 1.00E00 1.00E00 angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure (GO:0001998) 3 0 .30 - < 0.01 1.00E00 1.00E00 glycine biosynthetic process from serine (GO:0019264) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of melanosome organization (GO:1903056) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of heart rate by epinephrine-norepinephrine (GO:0001996) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by vasopressin (GO:0001992) 3 0 .30 - < 0.01 1.00E00 1.00E00 fatty acid beta-oxidation using acyl-CoA dehydrogenase (GO:0033539) 10 0 .99 - < 0.01 1.00E00 1.00E00 spermatid nucleus elongation (GO:0007290) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of transcription elongation by RNA polymerase I (GO:2001208) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of transcription elongation from RNA polymerase I promoter (GO:2001207) 1 0 .10 - < 0.01 1.00E00 1.00E00 rhombomere 3 development (GO:0021569) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of osteoclast development (GO:2001205) 3 0 .30 - < 0.01 1.00E00 1.00E00 rhombomere 2 development (GO:0021568) 2 0 .20 - < 0.01 1.00E00 1.00E00 hypoglossal nerve development (GO:0021566) 1 0 .10 - < 0.01 1.00E00 1.00E00 vagus nerve development (GO:0021564) 3 0 .30 - < 0.01 1.00E00 1.00E00 glossopharyngeal nerve development (GO:0021563) 4 0 .40 - < 0.01 1.00E00 1.00E00 abducens nerve development (GO:0021560) 2 0 .20 - < 0.01 1.00E00 1.00E00 glucose 1-phosphate metabolic process (GO:0019255) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure (GO:0001988) 1 0 .10 - < 0.01 1.00E00 1.00E00 carnitine metabolic process, CoA-linked (GO:0019254) 3 0 .30 - < 0.01 1.00E00 1.00E00 vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure (GO:0001987) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to membrane raft (GO:1903044) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of chondrocyte hypertrophy (GO:1903043) 1 0 .10 - < 0.01 1.00E00 1.00E00 artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure (GO:0001984) 1 0 .10 - < 0.01 1.00E00 1.00E00 baroreceptor response to increased systemic arterial blood pressure (GO:0001983) 1 0 .10 - < 0.01 1.00E00 1.00E00 spermatid nucleus differentiation (GO:0007289) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 regulation of chondrocyte hypertrophy (GO:1903041) 1 0 .10 - < 0.01 1.00E00 1.00E00 baroreceptor response to decreased systemic arterial blood pressure (GO:0001982) 2 0 .20 - < 0.01 1.00E00 1.00E00 sperm axoneme assembly (GO:0007288) 19 0 1.88 - < 0.01 4.08E-01 1.00E00 regulation of systemic arterial blood pressure by ischemic conditions (GO:0001980) 2 0 .20 - < 0.01 1.00E00 1.00E00 primary spermatocyte growth (GO:0007285) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone H2B ubiquitination (GO:0033523) 10 0 .99 - < 0.01 1.00E00 1.00E00 histone H2A ubiquitination (GO:0033522) 22 0 2.18 - < 0.01 2.56E-01 1.00E00 optic nerve development (GO:0021554) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 olfactory nerve development (GO:0021553) 2 0 .20 - < 0.01 1.00E00 1.00E00 medulla oblongata development (GO:0021550) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by chemoreceptor signaling (GO:0001979) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback (GO:0001978) 3 0 .30 - < 0.01 1.00E00 1.00E00 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione (GO:0019243) 4 0 .40 - < 0.01 1.00E00 1.00E00 methylglyoxal biosynthetic process (GO:0019242) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to amphetamine (GO:0001975) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 positive regulation of microtubule plus-end binding (GO:1903033) 2 0 .20 - < 0.01 1.00E00 1.00E00 citrulline biosynthetic process (GO:0019240) 2 0 .20 - < 0.01 1.00E00 1.00E00 G protein-coupled adenosine receptor signaling pathway (GO:0001973) 9 0 .89 - < 0.01 1.00E00 1.00E00 regulation of microtubule plus-end binding (GO:1903031) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of activation of membrane attack complex (GO:0001971) 2 0 .20 - < 0.01 1.00E00 1.00E00 neuromuscular synaptic transmission (GO:0007274) 20 0 1.98 - < 0.01 2.51E-01 1.00E00 synaptic transmission, cholinergic (GO:0007271) 10 0 .99 - < 0.01 1.00E00 1.00E00 neuron-neuron synaptic transmission (GO:0007270) 8 0 .79 - < 0.01 1.00E00 1.00E00 L-lysine catabolic process to acetyl-CoA via L-pipecolate (GO:0033514) 1 0 .10 - < 0.01 1.00E00 1.00E00 midbrain-hindbrain boundary initiation (GO:0021547) 1 0 .10 - < 0.01 1.00E00 1.00E00 rhombomere development (GO:0021546) 8 0 .79 - < 0.01 1.00E00 1.00E00 ammon gyrus development (GO:0021541) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to pheromone (GO:0019236) 10 0 .99 - < 0.01 1.00E00 1.00E00 positive regulation of opsonization (GO:1903028) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of opsonization (GO:1903027) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding (GO:1903026) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of RNA polymerase II regulatory region sequence-specific DNA binding (GO:1903025) 10 0 .99 - < 0.01 1.00E00 1.00E00 proprioception (GO:0019230) 4 0 .40 - < 0.01 1.00E00 1.00E00 floor plate morphogenesis (GO:0033505) 2 0 .20 - < 0.01 1.00E00 1.00E00 tyrosine phosphorylation of STAT protein (GO:0007260) 8 0 .79 - < 0.01 1.00E00 1.00E00 floor plate development (GO:0033504) 6 0 .59 - < 0.01 1.00E00 1.00E00 subthalamus development (GO:0021539) 2 0 .20 - < 0.01 1.00E00 1.00E00 epithalamus development (GO:0021538) 3 0 .30 - < 0.01 1.00E00 1.00E00 metanephric nephron tubule formation (GO:0072289) 3 0 .30 - < 0.01 1.00E00 1.00E00 neuronal action potential propagation (GO:0019227) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of glycoprotein metabolic process (GO:1903019) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 metanephric connecting tubule development (GO:0072286) 1 0 .10 - < 0.01 1.00E00 1.00E00 mesenchymal to epithelial transition involved in metanephric renal vesicle formation (GO:0072285) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of exo-alpha-sialidase activity (GO:1903016) 1 0 .10 - < 0.01 1.00E00 1.00E00 intramembranous ossification (GO:0001957) 6 0 .59 - < 0.01 1.00E00 1.00E00 metanephric renal vesicle morphogenesis (GO:0072283) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of exo-alpha-sialidase activity (GO:1903015) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of bone development (GO:1903012) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of bone development (GO:1903011) 1 0 .10 - < 0.01 1.00E00 1.00E00 JUN phosphorylation (GO:0007258) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of bone development (GO:1903010) 7 0 .69 - < 0.01 1.00E00 1.00E00 intestinal D-glucose absorption (GO:0001951) 3 0 .30 - < 0.01 1.00E00 1.00E00 activation of JNKK activity (GO:0007256) 5 0 .49 - < 0.01 1.00E00 1.00E00 cytoplasmic sequestering of NF-kappaB (GO:0007253) 5 0 .49 - < 0.01 1.00E00 1.00E00 commissural neuron differentiation in spinal cord (GO:0021528) 1 0 .10 - < 0.01 1.00E00 1.00E00 spinal cord association neuron differentiation (GO:0021527) 4 0 .40 - < 0.01 1.00E00 1.00E00 visceral motor neuron differentiation (GO:0021524) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of amniotic stem cell differentiation (GO:2000798) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of amniotic stem cell differentiation (GO:2000797) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of epithelial cell proliferation involved in lung morphogenesis (GO:2000795) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric glomerular capillary formation (GO:0072277) 2 0 .20 - < 0.01 1.00E00 1.00E00 metanephric glomerulus vasculature morphogenesis (GO:0072276) 2 0 .20 - < 0.01 1.00E00 1.00E00 sebaceous gland cell differentiation (GO:0001949) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric glomerulus morphogenesis (GO:0072275) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of Lys63-specific deubiquitinase activity (GO:1903007) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric glomerular basement membrane development (GO:0072274) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of protein K63-linked deubiquitination (GO:1903006) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal cell proliferation involved in lung development (GO:2000791) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal cell proliferation involved in lung development (GO:2000790) 2 0 .20 - < 0.01 1.00E00 1.00E00 lymphangiogenesis (GO:0001946) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 regulation of protein K63-linked deubiquitination (GO:1903004) 2 0 .20 - < 0.01 1.00E00 1.00E00 lymph vessel development (GO:0001945) 23 0 2.27 - < 0.01 2.61E-01 1.00E00 positive regulation of protein deubiquitination (GO:1903003) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of lipid transport across blood-brain barrier (GO:1903002) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of lipid transport across blood-brain barrier (GO:1903001) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of lipid transport across blood-brain barrier (GO:1903000) 1 0 .10 - < 0.01 1.00E00 1.00E00 dorsal spinal cord development (GO:0021516) 8 0 .79 - < 0.01 1.00E00 1.00E00 spinal cord anterior/posterior patterning (GO:0021512) 1 0 .10 - < 0.01 1.00E00 1.00E00 pattern specification involved in metanephros development (GO:0072268) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric capsule specification (GO:0072267) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of establishment of cell polarity regulating cell shape (GO:2000784) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric capsule formation (GO:0072266) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric capsule morphogenesis (GO:0072265) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of establishment of cell polarity regulating cell shape (GO:2000782) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric glomerular endothelium development (GO:0072264) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric glomerular mesangial cell proliferation involved in metanephros development (GO:0072262) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of cilium beat frequency involved in ciliary motility (GO:0060296) 5 0 .49 - < 0.01 1.00E00 1.00E00 osmosensory signaling pathway (GO:0007231) 3 0 .30 - < 0.01 1.00E00 1.00E00 transdifferentiation (GO:0060290) 6 0 .59 - < 0.01 1.00E00 1.00E00 floor plate formation (GO:0021508) 2 0 .20 - < 0.01 1.00E00 1.00E00 anterior neuropore closure (GO:0021506) 2 0 .20 - < 0.01 1.00E00 1.00E00 neural fold bending (GO:0021503) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia (GO:2000777) 2 0 .20 - < 0.01 1.00E00 1.00E00 neural fold elevation formation (GO:0021502) 3 0 .30 - < 0.01 1.00E00 1.00E00 prechordal plate formation (GO:0021501) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone H3-S10 phosphorylation involved in chromosome condensation (GO:2000775) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric glomerular mesangial cell development (GO:0072255) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric glomerular mesangial cell differentiation (GO:0072254) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of establishment or maintenance of cell polarity regulating cell shape (GO:2000771) 2 0 .20 - < 0.01 1.00E00 1.00E00 B-1 B cell homeostasis (GO:0001922) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of hh target transcription factor activity (GO:0007228) 2 0 .20 - < 0.01 1.00E00 1.00E00 signal transduction downstream of smoothened (GO:0007227) 3 0 .30 - < 0.01 1.00E00 1.00E00 epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of receptor recycling (GO:0001920) 4 0 .40 - < 0.01 1.00E00 1.00E00 patched ligand maturation (GO:0007225) 1 0 .10 - < 0.01 1.00E00 1.00E00 Wnt signaling pathway, calcium modulating pathway (GO:0007223) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of oocyte development (GO:0060282) 2 0 .20 - < 0.01 1.00E00 1.00E00 Notch receptor processing (GO:0007220) 9 0 .89 - < 0.01 1.00E00 1.00E00 regulation of establishment or maintenance of cell polarity regulating cell shape (GO:2000769) 2 0 .20 - < 0.01 1.00E00 1.00E00 metanephric glomerular visceral epithelial cell development (GO:0072249) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric glomerular visceral epithelial cell differentiation (GO:0072248) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis (GO:2000764) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process (GO:2000763) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric glomerular epithelium development (GO:0072244) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of N-terminal peptidyl-lysine acetylation (GO:2000761) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric DCT cell differentiation (GO:0072240) 1 0 .10 - < 0.01 1.00E00 1.00E00 G protein-coupled glutamate receptor signaling pathway (GO:0007216) 10 0 .99 - < 0.01 1.00E00 1.00E00 G protein-coupled acetylcholine receptor signaling pathway (GO:0007213) 9 0 .89 - < 0.01 1.00E00 1.00E00 serotonin receptor signaling pathway (GO:0007210) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of N-terminal peptidyl-lysine acetylation (GO:2000759) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of sphingomyelin catabolic process (GO:2000755) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of sphingomyelin catabolic process (GO:2000754) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of glucosylceramide catabolic process (GO:2000753) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric distal tubule development (GO:0072235) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of glucosylceramide catabolic process (GO:2000752) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore (GO:2000751) 1 0 .10 - < 0.01 1.00E00 1.00E00 killing by symbiont of host cells (GO:0001907) 3 0 .30 - < 0.01 1.00E00 1.00E00 metanephric thick ascending limb development (GO:0072233) 1 0 .10 - < 0.01 1.00E00 1.00E00 activation of membrane attack complex (GO:0001905) 1 0 .10 - < 0.01 1.00E00 1.00E00 phospholipase C-activating serotonin receptor signaling pathway (GO:0007208) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of respiratory burst (GO:0060268) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of respiratory burst involved in inflammatory response (GO:0060266) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of DNA replication origin binding (GO:1902595) 2 0 .20 - < 0.01 1.00E00 1.00E00 cyclic purine nucleotide metabolic process (GO:0052652) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 metanephric macula densa development (GO:0072227) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of anterior head development (GO:2000744) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of anterior head development (GO:2000742) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric glomerular mesangium development (GO:0072223) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal stem cell differentiation (GO:2000740) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric distal convoluted tubule development (GO:0072221) 3 0 .30 - < 0.01 1.00E00 1.00E00 metanephric ascending thin limb development (GO:0072218) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of metanephros development (GO:0072217) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation (GO:2000734) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation (GO:2000733) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of metanephros development (GO:0072215) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of calcium import into the mitochondrion (GO:0110099) 2 0 .20 - < 0.01 1.00E00 1.00E00 metanephric capsule development (GO:0072213) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of termination of RNA polymerase I transcription (GO:2000730) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of calcium import into the mitochondrion (GO:0110097) 3 0 .30 - < 0.01 1.00E00 1.00E00 multi-organism localization (GO:1902579) 8 0 .79 - < 0.01 1.00E00 1.00E00 protein localization to nucleolus (GO:1902570) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of mesenchymal cell proliferation involved in ureter development (GO:2000729) 2 0 .20 - < 0.01 1.00E00 1.00E00 metanephric mesangial cell differentiation (GO:0072209) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac vascular smooth muscle cell differentiation (GO:2000724) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric juxtaglomerular apparatus development (GO:0072206) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac vascular smooth muscle cell differentiation (GO:2000723) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric collecting duct development (GO:0072205) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of cardiac vascular smooth muscle cell differentiation (GO:2000722) 2 0 .20 - < 0.01 1.00E00 1.00E00 cell-cell signaling involved in metanephros development (GO:0072204) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation (GO:2000721) 2 0 .20 - < 0.01 1.00E00 1.00E00 cell proliferation involved in metanephros development (GO:0072203) 5 0 .49 - < 0.01 1.00E00 1.00E00 cell differentiation involved in metanephros development (GO:0072202) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal cell proliferation (GO:0072201) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal cell proliferation involved in ureter development (GO:0072200) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of activation of Janus kinase activity (GO:1902569) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of eosinophil activation (GO:1902568) 2 0 .20 - < 0.01 1.00E00 1.00E00 lens induction in camera-type eye (GO:0060235) 5 0 .49 - < 0.01 1.00E00 1.00E00 neuroblast delamination (GO:0060234) 1 0 .10 - < 0.01 1.00E00 1.00E00 mesenchymal to epithelial transition (GO:0060231) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric (GO:2000719) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of maintenance of mitotic sister chromatid cohesion, centromeric (GO:2000718) 1 0 .10 - < 0.01 1.00E00 1.00E00 vesicle-mediated intercellular transport (GO:0110077) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of ferroptosis (GO:0110076) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of ferroptosis (GO:0110075) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of retinal cone cell fate commitment (GO:0060226) 1 0 .10 - < 0.01 1.00E00 1.00E00 retinal rod cell fate commitment (GO:0060223) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of retinal cone cell fate commitment (GO:0060222) 1 0 .10 - < 0.01 1.00E00 1.00E00 retinal rod cell differentiation (GO:0060221) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 polyphosphate catabolic process (GO:0006798) 6 0 .59 - < 0.01 1.00E00 1.00E00 camera-type eye photoreceptor cell fate commitment (GO:0060220) 2 0 .20 - < 0.01 1.00E00 1.00E00 polyphosphate metabolic process (GO:0006797) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of dense core granule biogenesis (GO:2000707) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of dense core granule biogenesis (GO:2000706) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of dense core granule biogenesis (GO:2000705) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation (GO:2000703) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation (GO:2000702) 1 0 .10 - < 0.01 1.00E00 1.00E00 hemangioblast cell differentiation (GO:0060217) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of angiotensin-activated signaling pathway (GO:0110061) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of DNA N-glycosylase activity (GO:1902546) 1 0 .10 - < 0.01 1.00E00 1.00E00 endocardium formation (GO:0060214) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of DNA N-glycosylase activity (GO:1902544) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060212) 3 0 .30 - < 0.01 1.00E00 1.00E00 heme A biosynthetic process (GO:0006784) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of blood vessel endothelial cell differentiation (GO:0110059) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of blood vessel endothelial cell differentiation (GO:0110057) 1 0 .10 - < 0.01 1.00E00 1.00E00 metabolite repair (GO:0110051) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of protein linear polyubiquitination (GO:1902530) 1 0 .10 - < 0.01 1.00E00 1.00E00 Mo-molybdopterin cofactor biosynthetic process (GO:0006777) 6 0 .59 - < 0.01 1.00E00 1.00E00 vitamin A metabolic process (GO:0006776) 2 0 .20 - < 0.01 1.00E00 1.00E00 fat-soluble vitamin metabolic process (GO:0006775) 19 0 1.88 - < 0.01 4.08E-01 1.00E00 riboflavin metabolic process (GO:0006771) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to prostaglandin D stimulus (GO:0071799) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to prostaglandin D (GO:0071798) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein linear polyubiquitination (GO:1902528) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of protein monoubiquitination (GO:1902527) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of protein monoubiquitination (GO:1902525) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of protein K48-linked ubiquitination (GO:1902524) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of protein K63-linked ubiquitination (GO:1902523) 4 0 .40 - < 0.01 1.00E00 1.00E00 biotin metabolic process (GO:0006768) 1 0 .10 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum tubular network maintenance (GO:0071788) 1 0 .10 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum tubular network formation (GO:0071787) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of apoptotic DNA fragmentation (GO:1902512) 5 0 .49 - < 0.01 1.00E00 1.00E00 AMP phosphorylation (GO:0006756) 2 0 .20 - < 0.01 1.00E00 1.00E00 MHC class II protein complex assembly (GO:0002399) 1 0 .10 - < 0.01 1.00E00 1.00E00 MHC class Ib protein complex assembly (GO:0002398) 1 0 .10 - < 0.01 1.00E00 1.00E00 MHC class I protein complex assembly (GO:0002397) 2 0 .20 - < 0.01 1.00E00 1.00E00 MHC protein complex assembly (GO:0002396) 4 0 .40 - < 0.01 1.00E00 1.00E00 immune response in nasopharyngeal-associated lymphoid tissue (GO:0002395) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of DNA strand resection involved in replication fork processing (GO:0110026) 1 0 .10 - < 0.01 1.00E00 1.00E00 DNA strand resection involved in replication fork processing (GO:0110025) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle myoblast proliferation (GO:0110024) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle myoblast proliferation (GO:0110022) 2 0 .20 - < 0.01 1.00E00 1.00E00 FAD biosynthetic process (GO:0006747) 1 0 .10 - < 0.01 1.00E00 1.00E00 NADP biosynthetic process (GO:0006741) 4 0 .40 - < 0.01 1.00E00 1.00E00 NADPH regeneration (GO:0006740) 10 0 .99 - < 0.01 1.00E00 1.00E00 immune response in gut-associated lymphoid tissue (GO:0002387) 1 0 .10 - < 0.01 1.00E00 1.00E00 hepatic immune response (GO:0002384) 1 0 .10 - < 0.01 1.00E00 1.00E00 immune response in brain or nervous system (GO:0002383) 1 0 .10 - < 0.01 1.00E00 1.00E00 cap-independent translational initiation of linear mRNA (GO:0110017) 2 0 .20 - < 0.01 1.00E00 1.00E00 nuclear inner membrane organization (GO:0071765) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to P-body (GO:0110012) 3 0 .30 - < 0.01 1.00E00 1.00E00 nuclear membrane organization (GO:0071763) 23 0 2.27 - < 0.01 2.61E-01 1.00E00 regulation of basement membrane organization (GO:0110011) 5 0 .49 - < 0.01 1.00E00 1.00E00 NADH regeneration (GO:0006735) 6 0 .59 - < 0.01 1.00E00 1.00E00 plasmacytoid dendritic cell cytokine production (GO:0002373) 1 0 .10 - < 0.01 1.00E00 1.00E00 dendritic cell cytokine production (GO:0002371) 1 0 .10 - < 0.01 1.00E00 1.00E00 ncRNA deadenylation (GO:0110008) 1 0 .10 - < 0.01 1.00E00 1.00E00 triterpenoid metabolic process (GO:0006722) 1 0 .10 - < 0.01 1.00E00 1.00E00 gamma-delta T cell lineage commitment (GO:0002365) 1 0 .10 - < 0.01 1.00E00 1.00E00 NK T cell lineage commitment (GO:0002364) 1 0 .10 - < 0.01 1.00E00 1.00E00 sesquiterpenoid metabolic process (GO:0006714) 2 0 .20 - < 0.01 1.00E00 1.00E00 B cell homeostatic proliferation (GO:0002358) 2 0 .20 - < 0.01 1.00E00 1.00E00 detection of tumor cell (GO:0002355) 1 0 .10 - < 0.01 1.00E00 1.00E00 plasma kallikrein-kinin cascade (GO:0002353) 1 0 .10 - < 0.01 1.00E00 1.00E00 B cell negative selection (GO:0002352) 2 0 .20 - < 0.01 1.00E00 1.00E00 cholesterol catabolic process (GO:0006707) 6 0 .59 - < 0.01 1.00E00 1.00E00 mineralocorticoid biosynthetic process (GO:0006705) 1 0 .10 - < 0.01 1.00E00 1.00E00 estrogen biosynthetic process (GO:0006703) 5 0 .49 - < 0.01 1.00E00 1.00E00 androgen biosynthetic process (GO:0006702) 4 0 .40 - < 0.01 1.00E00 1.00E00 progesterone biosynthetic process (GO:0006701) 2 0 .20 - < 0.01 1.00E00 1.00E00 histamine production involved in inflammatory response (GO:0002349) 5 0 .49 - < 0.01 1.00E00 1.00E00 C21-steroid hormone biosynthetic process (GO:0006700) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell (GO:2001190) 1 0 .10 - < 0.01 1.00E00 1.00E00 B-1a B cell differentiation (GO:0002337) 3 0 .30 - < 0.01 1.00E00 1.00E00 B-1 B cell lineage commitment (GO:0002336) 1 0 .10 - < 0.01 1.00E00 1.00E00 transitional two stage B cell differentiation (GO:0002334) 1 0 .10 - < 0.01 1.00E00 1.00E00 transitional one stage B cell differentiation (GO:0002333) 1 0 .10 - < 0.01 1.00E00 1.00E00 transitional stage B cell differentiation (GO:0002332) 2 0 .20 - < 0.01 1.00E00 1.00E00 ER-associated misfolded protein catabolic process (GO:0071712) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 positive regulation of mediator complex assembly (GO:2001178) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mediator complex assembly (GO:2001176) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of histone H2B conserved C-terminal lysine ubiquitination (GO:2001173) 1 0 .10 - < 0.01 1.00E00 1.00E00 immunoglobulin heavy chain V-D-J recombination (GO:0071707) 3 0 .30 - < 0.01 1.00E00 1.00E00 tumor necrosis factor superfamily cytokine production (GO:0071706) 6 0 .59 - < 0.01 1.00E00 1.00E00 galactose catabolic process via UDP-galactose (GO:0033499) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of MAPK export from nucleus (GO:0071701) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of histone H2B ubiquitination (GO:2001168) 4 0 .40 - < 0.01 1.00E00 1.00E00 cholesterol biosynthetic process via lathosterol (GO:0033490) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of histone H2B ubiquitination (GO:2001166) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues (GO:2001165) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues (GO:2001163) 1 0 .10 - < 0.01 1.00E00 1.00E00 memory B cell differentiation (GO:0002319) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of histone H3-K79 methylation (GO:2001162) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of histone H3-K79 methylation (GO:2001161) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of histone H3-K79 methylation (GO:2001160) 3 0 .30 - < 0.01 1.00E00 1.00E00 cholesterol biosynthetic process via desmosterol (GO:0033489) 1 0 .10 - < 0.01 1.00E00 1.00E00 cholesterol biosynthetic process via 24,25-dihydrolanosterol (GO:0033488) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of renal water transport (GO:2001153) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of renal water transport (GO:2001151) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of dipeptide transmembrane transport (GO:2001150) 2 0 .20 - < 0.01 1.00E00 1.00E00 CD8-positive, alpha-beta T cell differentiation involved in immune response (GO:0002302) 2 0 .20 - < 0.01 1.00E00 1.00E00 CD8-positive, alpha-beta intraepithelial T cell differentiation (GO:0002300) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of dipeptide transmembrane transport (GO:2001148) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity (GO:2001145) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity (GO:2001144) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of phospholipid transport (GO:2001139) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of endocytic recycling (GO:2001136) 1 0 .10 - < 0.01 1.00E00 1.00E00 specification of axis polarity (GO:0065001) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of cellular response to hepatocyte growth factor stimulus (GO:2001113) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cellular response to hepatocyte growth factor stimulus (GO:2001112) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of lens epithelial cell proliferation (GO:2001111) 1 0 .10 - < 0.01 1.00E00 1.00E00 G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199) 4 0 .40 - < 0.01 1.00E00 1.00E00 adenylate cyclase-inhibiting serotonin receptor signaling pathway (GO:0007198) 2 0 .20 - < 0.01 1.00E00 1.00E00 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway (GO:0007197) 4 0 .40 - < 0.01 1.00E00 1.00E00 adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway (GO:0007196) 3 0 .30 - < 0.01 1.00E00 1.00E00 adenylate cyclase-inhibiting dopamine receptor signaling pathway (GO:0007195) 2 0 .20 - < 0.01 1.00E00 1.00E00 adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of lens epithelial cell proliferation (GO:2001109) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of Rho guanyl-nucleotide exchange factor activity (GO:2001108) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of Rho guanyl-nucleotide exchange factor activity (GO:2001106) 2 0 .20 - < 0.01 1.00E00 1.00E00 selenium compound metabolic process (GO:0001887) 3 0 .30 - < 0.01 1.00E00 1.00E00 Mullerian duct regression (GO:0001880) 3 0 .30 - < 0.01 1.00E00 1.00E00 transmembrane receptor protein tyrosine phosphatase signaling pathway (GO:0007185) 1 0 .10 - < 0.01 1.00E00 1.00E00 transforming growth factor beta receptor complex assembly (GO:0007181) 3 0 .30 - < 0.01 1.00E00 1.00E00 detection of yeast (GO:0001879) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of epidermal growth factor-activated receptor activity (GO:0007175) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 epidermal growth factor catabolic process (GO:0007174) 1 0 .10 - < 0.01 1.00E00 1.00E00 signal complex assembly (GO:0007172) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal cell proliferation involved in ureter development (GO:0072199) 3 0 .30 - < 0.01 1.00E00 1.00E00 mesenchymal cell proliferation involved in ureter development (GO:0072198) 1 0 .10 - < 0.01 1.00E00 1.00E00 kidney smooth muscle cell differentiation (GO:0072195) 1 0 .10 - < 0.01 1.00E00 1.00E00 kidney smooth muscle tissue development (GO:0072194) 1 0 .10 - < 0.01 1.00E00 1.00E00 ureter smooth muscle cell differentiation (GO:0072193) 4 0 .40 - < 0.01 1.00E00 1.00E00 NK T cell proliferation (GO:0001866) 2 0 .20 - < 0.01 1.00E00 1.00E00 ureter epithelial cell differentiation (GO:0072192) 1 0 .10 - < 0.01 1.00E00 1.00E00 NK T cell differentiation (GO:0001865) 6 0 .59 - < 0.01 1.00E00 1.00E00 ureter smooth muscle development (GO:0072191) 4 0 .40 - < 0.01 1.00E00 1.00E00 ureter urothelium development (GO:0072190) 2 0 .20 - < 0.01 1.00E00 1.00E00 receptor guanylyl cyclase signaling pathway (GO:0007168) 8 0 .79 - < 0.01 1.00E00 1.00E00 establishment of tissue polarity (GO:0007164) 23 0 2.27 - < 0.01 2.61E-01 1.00E00 mesonephric duct morphogenesis (GO:0072180) 1 0 .10 - < 0.01 1.00E00 1.00E00 nephric duct formation (GO:0072179) 2 0 .20 - < 0.01 1.00E00 1.00E00 nephric duct morphogenesis (GO:0072178) 6 0 .59 - < 0.01 1.00E00 1.00E00 mesonephric duct development (GO:0072177) 2 0 .20 - < 0.01 1.00E00 1.00E00 nephric duct development (GO:0072176) 7 0 .69 - < 0.01 1.00E00 1.00E00 metanephric tubule formation (GO:0072174) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac muscle cell myoblast differentiation (GO:2000691) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle cell myoblast differentiation (GO:2000690) 1 0 .10 - < 0.01 1.00E00 1.00E00 mesonephric tubule formation (GO:0072172) 5 0 .49 - < 0.01 1.00E00 1.00E00 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway (GO:0001844) 2 0 .20 - < 0.01 1.00E00 1.00E00 female meiosis II (GO:0007147) 2 0 .20 - < 0.01 1.00E00 1.00E00 neural plate development (GO:0001840) 9 0 .89 - < 0.01 1.00E00 1.00E00 regulation of cellular response to X-ray (GO:2000683) 1 0 .10 - < 0.01 1.00E00 1.00E00 neural plate morphogenesis (GO:0001839) 6 0 .59 - < 0.01 1.00E00 1.00E00 male somatic sex determination (GO:0019102) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric mesenchymal cell differentiation (GO:0072162) 1 0 .10 - < 0.01 1.00E00 1.00E00 blastocyst hatching (GO:0001835) 31 0 3.07 - < 0.01 1.09E-01 9.09E-01 mesenchymal cell differentiation involved in kidney development (GO:0072161) 3 0 .30 - < 0.01 1.00E00 1.00E00 trophectodermal cell proliferation (GO:0001834) 4 0 .40 - < 0.01 1.00E00 1.00E00 male germ-line sex determination (GO:0019100) 2 0 .20 - < 0.01 1.00E00 1.00E00 nephron tubule epithelial cell differentiation (GO:0072160) 2 0 .20 - < 0.01 1.00E00 1.00E00 inner cell mass cell proliferation (GO:0001833) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 blastocyst growth (GO:0001832) 26 0 2.57 - < 0.01 1.65E-01 1.00E00 trophectodermal cellular morphogenesis (GO:0001831) 2 0 .20 - < 0.01 1.00E00 1.00E00 cloacal septation (GO:0060197) 1 0 .10 - < 0.01 1.00E00 1.00E00 trophectodermal cell fate commitment (GO:0001830) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of type B pancreatic cell apoptotic process (GO:2000676) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of type B pancreatic cell apoptotic process (GO:2000675) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of type B pancreatic cell apoptotic process (GO:2000674) 10 0 .99 - < 0.01 1.00E00 1.00E00 trophectodermal cell differentiation (GO:0001829) 23 0 2.27 - < 0.01 2.61E-01 1.00E00 negative regulation of motor neuron apoptotic process (GO:2000672) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of motor neuron apoptotic process (GO:2000671) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of dendritic cell apoptotic process (GO:2000670) 4 0 .40 - < 0.01 1.00E00 1.00E00 inflammasome complex assembly (GO:0140632) 3 0 .30 - < 0.01 1.00E00 1.00E00 meiotic prophase I (GO:0007128) 7 0 .69 - < 0.01 1.00E00 1.00E00 histamine secretion (GO:0001821) 8 0 .79 - < 0.01 1.00E00 1.00E00 cell cycle switching (GO:0060184) 1 0 .10 - < 0.01 1.00E00 1.00E00 apelin receptor signaling pathway (GO:0060183) 2 0 .20 - < 0.01 1.00E00 1.00E00 female mating behavior (GO:0060180) 10 0 .99 - < 0.01 1.00E00 1.00E00 positive regulation of antibody-dependent cellular cytotoxicity (GO:0001815) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of antibody-dependent cellular cytotoxicity (GO:0001813) 1 0 .10 - < 0.01 1.00E00 1.00E00 male mating behavior (GO:0060179) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of exocyst localization (GO:0060178) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of angiotensin metabolic process (GO:0060177) 3 0 .30 - < 0.01 1.00E00 1.00E00 endomitotic cell cycle (GO:0007113) 2 0 .20 - < 0.01 1.00E00 1.00E00 male meiosis cytokinesis (GO:0007112) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein-DNA complex disassembly (GO:0032986) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 mitochondrial respiratory chain complex I assembly (GO:0032981) 53 0 5.24 - < 0.01 1.34E-02 2.62E-01 negative regulation of apolipoprotein binding (GO:2000657) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of apolipoprotein binding (GO:2000656) 1 0 .10 - < 0.01 1.00E00 1.00E00 mesenchymal cell proliferation involved in ureteric bud development (GO:0072138) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of cellular response to testosterone stimulus (GO:2000655) 1 0 .10 - < 0.01 1.00E00 1.00E00 condensed mesenchymal cell proliferation (GO:0072137) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of cellular response to testosterone stimulus (GO:2000654) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric mesenchymal cell proliferation involved in metanephros development (GO:0072136) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of genetic imprinting (GO:2000653) 7 0 .69 - < 0.01 1.00E00 1.00E00 kidney mesenchymal cell proliferation (GO:0072135) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of type IV hypersensitivity (GO:0001808) 2 0 .20 - < 0.01 1.00E00 1.00E00 nephrogenic mesenchyme morphogenesis (GO:0072134) 2 0 .20 - < 0.01 1.00E00 1.00E00 metanephric mesenchyme morphogenesis (GO:0072133) 2 0 .20 - < 0.01 1.00E00 1.00E00 type IV hypersensitivity (GO:0001806) 1 0 .10 - < 0.01 1.00E00 1.00E00 kidney mesenchyme morphogenesis (GO:0072131) 2 0 .20 - < 0.01 1.00E00 1.00E00 renal capsule specification (GO:0072130) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of adenosine receptor signaling pathway (GO:0060169) 1 0 .10 - < 0.01 1.00E00 1.00E00 iron-sulfur cluster transmembrane transport (GO:1902497) 1 0 .10 - < 0.01 1.00E00 1.00E00 olfactory pit development (GO:0060166) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitotic centrosome separation (GO:0007100) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of sperm capacitation (GO:1902490) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein insertion into mitochondrial inner membrane from matrix (GO:0032979) 4 0 .40 - < 0.01 1.00E00 1.00E00 protein insertion into membrane from inner side (GO:0032978) 5 0 .49 - < 0.01 1.00E00 1.00E00 release of matrix enzymes from mitochondria (GO:0032976) 1 0 .10 - < 0.01 1.00E00 1.00E00 amino acid transmembrane export from vacuole (GO:0032974) 1 0 .10 - < 0.01 1.00E00 1.00E00 amino acid export across plasma membrane (GO:0032973) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of stem cell proliferation (GO:2000648) 24 0 2.37 - < 0.01 1.63E-01 1.00E00 regulation of muscle filament sliding (GO:0032971) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of stem cell proliferation (GO:2000647) 3 0 .30 - < 0.01 1.00E00 1.00E00 renal capsule formation (GO:0072129) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of receptor catabolic process (GO:2000646) 8 0 .79 - < 0.01 1.00E00 1.00E00 renal capsule morphogenesis (GO:0072128) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of receptor catabolic process (GO:2000645) 3 0 .30 - < 0.01 1.00E00 1.00E00 renal capsule development (GO:0072127) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of receptor catabolic process (GO:2000644) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 positive regulation of early endosome to late endosome transport (GO:2000643) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of glomerular mesangial cell proliferation (GO:0072125) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of early endosome to late endosome transport (GO:2000642) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of early endosome to late endosome transport (GO:2000641) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 positive regulation of SREBP signaling pathway (GO:2000640) 1 0 .10 - < 0.01 1.00E00 1.00E00 milk ejection reflex (GO:0060156) 1 0 .10 - < 0.01 1.00E00 1.00E00 platelet dense granule organization (GO:0060155) 5 0 .49 - < 0.01 1.00E00 1.00E00 cytotoxic T cell pyroptotic process (GO:1902483) 1 0 .10 - < 0.01 1.00E00 1.00E00 microtubule-based peroxisome localization (GO:0060152) 2 0 .20 - < 0.01 1.00E00 1.00E00 peroxisome localization (GO:0060151) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein localization to mitotic spindle (GO:1902480) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 negative regulation of SREBP signaling pathway (GO:2000639) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of inositol trisphosphate biosynthetic process (GO:0032962) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of SREBP signaling pathway (GO:2000638) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of inositol trisphosphate biosynthetic process (GO:0032960) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of primary miRNA processing (GO:2000635) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of primary miRNA processing (GO:2000634) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of pre-miRNA processing (GO:2000632) 2 0 .20 - < 0.01 1.00E00 1.00E00 pronephros morphogenesis (GO:0072114) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of pre-miRNA processing (GO:2000631) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of miRNA metabolic process (GO:2000630) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to synapse (GO:1902474) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of cytokinetic process (GO:0032954) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of miRNA metabolic process (GO:2000629) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of miRNA metabolic process (GO:2000628) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 positive regulation of miRNA catabolic process (GO:2000627) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0072108) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of miRNA catabolic process (GO:2000625) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of ureteric bud formation (GO:0072107) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of ureteric bud formation (GO:0072106) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:2000623) 4 0 .40 - < 0.01 1.00E00 1.00E00 ureteric peristalsis (GO:0072105) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:2000622) 4 0 .40 - < 0.01 1.00E00 1.00E00 glomerular capillary formation (GO:0072104) 5 0 .49 - < 0.01 1.00E00 1.00E00 glomerulus vasculature morphogenesis (GO:0072103) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of histone H4-K16 acetylation (GO:2000620) 2 0 .20 - < 0.01 1.00E00 1.00E00 glomerulus morphogenesis (GO:0072102) 10 0 .99 - < 0.01 1.00E00 1.00E00 specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway (GO:0072101) 1 0 .10 - < 0.01 1.00E00 1.00E00 specification of ureteric bud anterior/posterior symmetry (GO:0072100) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of apoptotic process by virus (GO:0060139) 3 0 .30 - < 0.01 1.00E00 1.00E00 maternal process involved in parturition (GO:0060137) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of histone H3-K27 trimethylation (GO:1902466) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of histone H3-K27 trimethylation (GO:1902464) 2 0 .20 - < 0.01 1.00E00 1.00E00 somatotropin secreting cell development (GO:0060133) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to cell leading edge (GO:1902463) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of mesenchymal stem cell proliferation (GO:1902462) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal stem cell proliferation (GO:1902460) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of histone H4-K16 acetylation (GO:2000619) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of histone H4-K16 acetylation (GO:2000618) 7 0 .69 - < 0.01 1.00E00 1.00E00 secretion by tissue (GO:0032941) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 positive regulation of histone H3-K9 acetylation (GO:2000617) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of histone H3-K9 acetylation (GO:2000616) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of histone H3-K9 acetylation (GO:2000615) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 positive regulation of thyroid-stimulating hormone secretion (GO:2000614) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of thyroid-stimulating hormone secretion (GO:2000612) 2 0 .20 - < 0.01 1.00E00 1.00E00 thyroid-stimulating hormone-secreting cell differentiation (GO:0060129) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of stem cell population maintenance (GO:1902459) 10 0 .99 - < 0.01 1.00E00 1.00E00 corticotropin hormone secreting cell differentiation (GO:0060128) 2 0 .20 - < 0.01 1.00E00 1.00E00 somatotropin secreting cell differentiation (GO:0060126) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of growth hormone secretion (GO:0060125) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of stem cell population maintenance (GO:1902455) 3 0 .30 - < 0.01 1.00E00 1.00E00 bile acid biosynthetic process (GO:0006699) 9 0 .89 - < 0.01 1.00E00 1.00E00 vestibular receptor cell stereocilium organization (GO:0060121) 1 0 .10 - < 0.01 1.00E00 1.00E00 cholesterol biosynthetic process (GO:0006695) 29 0 2.87 - < 0.01 1.06E-01 8.97E-01 negative regulation of translation in response to oxidative stress (GO:0032938) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cell proliferation involved in mesonephros development (GO:2000607) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cell proliferation involved in mesonephros development (GO:2000606) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of Arp2/3 complex-mediated actin nucleation (GO:2000601) 10 0 .99 - < 0.01 1.00E00 1.00E00 vestibular receptor cell development (GO:0060118) 1 0 .10 - < 0.01 1.00E00 1.00E00 auditory receptor cell development (GO:0060117) 26 0 2.57 - < 0.01 1.65E-01 1.00E00 vestibular receptor cell morphogenesis (GO:0060116) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death (GO:1902445) 3 0 .30 - < 0.01 1.00E00 1.00E00 vestibular receptor cell differentiation (GO:0060114) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of ripoptosome assembly involved in necroptotic process (GO:1902443) 2 0 .20 - < 0.01 1.00E00 1.00E00 generation of ovulation cycle rhythm (GO:0060112) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of ripoptosome assembly involved in necroptotic process (GO:1902442) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein localization to mitotic spindle pole body (GO:1902440) 1 0 .10 - < 0.01 1.00E00 1.00E00 sphingomyelin catabolic process (GO:0006685) 7 0 .69 - < 0.01 1.00E00 1.00E00 galactosylceramide catabolic process (GO:0006683) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of activin receptor signaling pathway (GO:0032927) 8 0 .79 - < 0.01 1.00E00 1.00E00 galactosylceramide biosynthetic process (GO:0006682) 6 0 .59 - < 0.01 1.00E00 1.00E00 galactosylceramide metabolic process (GO:0006681) 8 0 .79 - < 0.01 1.00E00 1.00E00 glucosylceramide catabolic process (GO:0006680) 2 0 .20 - < 0.01 1.00E00 1.00E00 putrescine acetylation (GO:0032920) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of male mating behavior (GO:1902437) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of male mating behavior (GO:1902436) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of male mating behavior (GO:1902435) 3 0 .30 - < 0.01 1.00E00 1.00E00 glucosylceramide biosynthetic process (GO:0006679) 2 0 .20 - < 0.01 1.00E00 1.00E00 glucosylceramide metabolic process (GO:0006678) 5 0 .49 - < 0.01 1.00E00 1.00E00 glycosylceramide metabolic process (GO:0006677) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 spermine acetylation (GO:0032919) 1 0 .10 - < 0.01 1.00E00 1.00E00 spermidine acetylation (GO:0032918) 2 0 .20 - < 0.01 1.00E00 1.00E00 polyamine acetylation (GO:0032917) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of transforming growth factor beta3 production (GO:0032916) 2 0 .20 - < 0.01 1.00E00 1.00E00 phytosphingosine metabolic process (GO:0006671) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of transforming growth factor beta2 production (GO:0032915) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of transforming growth factor beta1 production (GO:0032914) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of transforming growth factor beta3 production (GO:0032913) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of transforming growth factor beta3 production (GO:0032910) 4 0 .40 - < 0.01 1.00E00 1.00E00 olfactory placode morphogenesis (GO:0071699) 3 0 .30 - < 0.01 1.00E00 1.00E00 olfactory placode development (GO:0071698) 3 0 .30 - < 0.01 1.00E00 1.00E00 ectodermal placode morphogenesis (GO:0071697) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 maintenance of protein location in extracellular region (GO:0071694) 6 0 .59 - < 0.01 1.00E00 1.00E00 protein transport within extracellular region (GO:0071693) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of attachment of mitotic spindle microtubules to kinetochore (GO:1902425) 3 0 .30 - < 0.01 1.00E00 1.00E00 cardiac muscle thin filament assembly (GO:0071691) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of attachment of mitotic spindle microtubules to kinetochore (GO:1902423) 3 0 .30 - < 0.01 1.00E00 1.00E00 sphinganine-1-phosphate biosynthetic process (GO:0006669) 1 0 .10 - < 0.01 1.00E00 1.00E00 sphinganine-1-phosphate metabolic process (GO:0006668) 2 0 .20 - < 0.01 1.00E00 1.00E00 sphinganine metabolic process (GO:0006667) 3 0 .30 - < 0.01 1.00E00 1.00E00 3-keto-sphinganine metabolic process (GO:0006666) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of transforming growth factor beta2 production (GO:0032909) 6 0 .59 - < 0.01 1.00E00 1.00E00 transforming growth factor beta1 production (GO:0032905) 1 0 .10 - < 0.01 1.00E00 1.00E00 phosphatidylserine catabolic process (GO:0006660) 2 0 .20 - < 0.01 1.00E00 1.00E00 nerve growth factor production (GO:0032902) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of neurotrophin production (GO:0032901) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of neurotrophin production (GO:0032900) 1 0 .10 - < 0.01 1.00E00 1.00E00 TORC2 signaling (GO:0038203) 6 0 .59 - < 0.01 1.00E00 1.00E00 striated muscle myosin thick filament assembly (GO:0071688) 2 0 .20 - < 0.01 1.00E00 1.00E00 organism emergence from protective structure (GO:0071684) 31 0 3.07 - < 0.01 1.09E-01 9.08E-01 positive regulation of mRNA binding (GO:1902416) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of mRNA binding (GO:1902415) 10 0 .99 - < 0.01 1.00E00 1.00E00 cellular response to indole-3-methanol (GO:0071681) 5 0 .49 - < 0.01 1.00E00 1.00E00 response to indole-3-methanol (GO:0071680) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of mitotic cytokinesis (GO:1902412) 3 0 .30 - < 0.01 1.00E00 1.00E00 phosphatidylglycerol biosynthetic process (GO:0006655) 9 0 .89 - < 0.01 1.00E00 1.00E00 alpha-beta intraepithelial T cell differentiation (GO:0002299) 1 0 .10 - < 0.01 1.00E00 1.00E00 T-helper 1 cell lineage commitment (GO:0002296) 4 0 .40 - < 0.01 1.00E00 1.00E00 olfactory bulb axon guidance (GO:0071678) 1 0 .10 - < 0.01 1.00E00 1.00E00 smooth muscle cell chemotaxis (GO:0071670) 1 0 .10 - < 0.01 1.00E00 1.00E00 phospholipid transfer to membrane (GO:0006649) 2 0 .20 - < 0.01 1.00E00 1.00E00 monocyte activation involved in immune response (GO:0002280) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of IP-10 production (GO:0071660) 1 0 .10 - < 0.01 1.00E00 1.00E00 tRNA demethylation (GO:1990983) 1 0 .10 - < 0.01 1.00E00 1.00E00 eosinophil activation involved in immune response (GO:0002278) 1 0 .10 - < 0.01 1.00E00 1.00E00 myeloid dendritic cell activation involved in immune response (GO:0002277) 3 0 .30 - < 0.01 1.00E00 1.00E00 basophil activation involved in immune response (GO:0002276) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of granulocyte colony-stimulating factor production (GO:0071656) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of chemokine (C-C motif) ligand 1 production (GO:0071654) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of chemokine (C-C motif) ligand 1 production (GO:0071652) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of chemokine (C-C motif) ligand 5 production (GO:0071651) 4 0 .40 - < 0.01 1.00E00 1.00E00 protein targeting to peroxisome (GO:0006625) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 protein retention in ER lumen (GO:0006621) 7 0 .69 - < 0.01 1.00E00 1.00E00 leukocyte activation involved in inflammatory response (GO:0002269) 3 0 .30 - < 0.01 1.00E00 1.00E00 follicular dendritic cell differentiation (GO:0002268) 2 0 .20 - < 0.01 1.00E00 1.00E00 follicular dendritic cell activation (GO:0002266) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of chemokine (C-C motif) ligand 4 production (GO:0071644) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of chemokine (C-C motif) ligand 4 production (GO:0071643) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage inflammatory protein 1 alpha production (GO:0071642) 2 0 .20 - < 0.01 1.00E00 1.00E00 modulation by host of viral RNA-binding transcription factor activity (GO:1990969) 1 0 .10 - < 0.01 1.00E00 1.00E00 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition (GO:0006617) 1 0 .10 - < 0.01 1.00E00 1.00E00 modulation by host of RNA binding by virus (GO:1990968) 1 0 .10 - < 0.01 1.00E00 1.00E00 ATP generation from poly-ADP-D-ribose (GO:1990966) 4 0 .40 - < 0.01 1.00E00 1.00E00 ribosomal protein import into nucleus (GO:0006610) 3 0 .30 - < 0.01 1.00E00 1.00E00 basophil homeostasis (GO:1990960) 1 0 .10 - < 0.01 1.00E00 1.00E00 kinin cascade (GO:0002254) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of monocyte chemotactic protein-1 production (GO:0071638) 5 0 .49 - < 0.01 1.00E00 1.00E00 nuclear protein quality control by the ubiquitin-proteasome system (GO:0071630) 2 0 .20 - < 0.01 1.00E00 1.00E00 homogentisate metabolic process (GO:1901999) 1 0 .10 - < 0.01 1.00E00 1.00E00 eosinophil homeostasis (GO:1990959) 2 0 .20 - < 0.01 1.00E00 1.00E00 NLS-bearing protein import into nucleus (GO:0006607) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of meiotic cell cycle phase transition (GO:1901994) 2 0 .20 - < 0.01 1.00E00 1.00E00 intramanchette transport (GO:1990953) 1 0 .10 - < 0.01 1.00E00 1.00E00 creatine biosynthetic process (GO:0006601) 2 0 .20 - < 0.01 1.00E00 1.00E00 creatine metabolic process (GO:0006600) 2 0 .20 - < 0.01 1.00E00 1.00E00 cytoplasm protein quality control by the ubiquitin-proteasome system (GO:0071629) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of granulocyte chemotaxis (GO:0071623) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of inward rectifier potassium channel activity (GO:1901980) 1 0 .10 - < 0.01 1.00E00 1.00E00 acyl-CoA biosynthetic process (GO:0071616) 20 0 1.98 - < 0.01 2.51E-01 1.00E00 regulation of inward rectifier potassium channel activity (GO:1901979) 5 0 .49 - < 0.01 1.00E00 1.00E00 peptidyl-aspartic acid autophosphorylation (GO:1990938) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of antimicrobial peptide production (GO:0002225) 4 0 .40 - < 0.01 1.00E00 1.00E00 chemokine (C-C motif) ligand 5 production (GO:0071609) 1 0 .10 - < 0.01 1.00E00 1.00E00 macrophage inflammatory protein-1 alpha production (GO:0071608) 1 0 .10 - < 0.01 1.00E00 1.00E00 transforming growth factor beta production (GO:0071604) 4 0 .40 - < 0.01 1.00E00 1.00E00 endothelial cell-cell adhesion (GO:0071603) 2 0 .20 - < 0.01 1.00E00 1.00E00 phytosphingosine biosynthetic process (GO:0071602) 1 0 .10 - < 0.01 1.00E00 1.00E00 beta-alanine biosynthetic process via 3-ureidopropionate (GO:0033396) 1 0 .10 - < 0.01 1.00E00 1.00E00 calcium ion regulated lysosome exocytosis (GO:1990927) 2 0 .20 - < 0.01 1.00E00 1.00E00 short-term synaptic potentiation (GO:1990926) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cell proliferation involved in outflow tract morphogenesis (GO:1901964) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cell proliferation involved in outflow tract morphogenesis (GO:1901963) 3 0 .30 - < 0.01 1.00E00 1.00E00 putrescine biosynthetic process from arginine, using agmatinase (GO:0033389) 1 0 .10 - < 0.01 1.00E00 1.00E00 putrescine biosynthetic process from arginine (GO:0033388) 1 0 .10 - < 0.01 1.00E00 1.00E00 putrescine biosynthetic process from ornithine (GO:0033387) 3 0 .30 - < 0.01 1.00E00 1.00E00 maintenance of granzyme B location in T cell secretory granule (GO:0033382) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of retrograde dense core granule transport (GO:1901956) 1 0 .10 - < 0.01 1.00E00 1.00E00 granzyme B localization to T cell secretory granule (GO:0033380) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of retrograde dense core granule transport (GO:1901954) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of anterograde dense core granule transport (GO:1901953) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal cell apoptotic process (GO:2001054) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of anterograde dense core granule transport (GO:1901951) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal cell apoptotic process (GO:2001053) 7 0 .69 - < 0.01 1.00E00 1.00E00 dense core granule transport (GO:1901950) 7 0 .69 - < 0.01 1.00E00 1.00E00 response to psychosocial stress (GO:1990911) 2 0 .20 - < 0.01 1.00E00 1.00E00 somatic diversification of immunoglobulins involved in immune response (GO:0002208) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 positive regulation of MHC class I biosynthetic process (GO:0045345) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of MHC class I biosynthetic process (GO:0045344) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of MHC class I biosynthetic process (GO:0045343) 6 0 .59 - < 0.01 1.00E00 1.00E00 maintenance of protease location in T cell secretory granule (GO:0033379) 1 0 .10 - < 0.01 1.00E00 1.00E00 maintenance of protein location in T cell secretory granule (GO:0033377) 1 0 .10 - < 0.01 1.00E00 1.00E00 protease localization to T cell secretory granule (GO:0033375) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to T cell secretory granule (GO:0033374) 1 0 .10 - < 0.01 1.00E00 1.00E00 maintenance of protease location in mast cell secretory granule (GO:0033373) 1 0 .10 - < 0.01 1.00E00 1.00E00 T cell secretory granule organization (GO:0033371) 1 0 .10 - < 0.01 1.00E00 1.00E00 maintenance of protein location in mast cell secretory granule (GO:0033370) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of integrin-mediated signaling pathway (GO:2001045) 3 0 .30 - < 0.01 1.00E00 1.00E00 farnesyl diphosphate metabolic process (GO:0045338) 4 0 .40 - < 0.01 1.00E00 1.00E00 farnesyl diphosphate biosynthetic process (GO:0045337) 3 0 .30 - < 0.01 1.00E00 1.00E00 protease localization to mast cell secretory granule (GO:0033368) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to mast cell secretory granule (GO:0033367) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to secretory granule (GO:0033366) 3 0 .30 - < 0.01 1.00E00 1.00E00 mast cell secretory granule organization (GO:0033364) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of cellular response to drug (GO:2001038) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of tongue muscle cell differentiation (GO:2001037) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of tongue muscle cell differentiation (GO:2001035) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of double-strand break repair via nonhomologous end joining (GO:2001034) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 negative regulation of double-strand break repair via nonhomologous end joining (GO:2001033) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of double-strand break repair via nonhomologous end joining (GO:2001032) 23 0 2.27 - < 0.01 2.61E-01 1.00E00 positive regulation of cellular glucuronidation (GO:2001031) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cellular glucuronidation (GO:2001030) 1 0 .10 - < 0.01 1.00E00 1.00E00 late viral transcription (GO:0019086) 3 0 .30 - < 0.01 1.00E00 1.00E00 early viral transcription (GO:0019085) 2 0 .20 - < 0.01 1.00E00 1.00E00 carnitine biosynthetic process (GO:0045329) 1 0 .10 - < 0.01 1.00E00 1.00E00 viral transcription (GO:0019083) 5 0 .49 - < 0.01 1.00E00 1.00E00 viral protein processing (GO:0019082) 2 0 .20 - < 0.01 1.00E00 1.00E00 viral translation (GO:0019081) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 viral gene expression (GO:0019080) 21 0 2.08 - < 0.01 2.52E-01 1.00E00 S-adenosylmethionine cycle (GO:0033353) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of cellular glucuronidation (GO:2001029) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of response to drug (GO:2001024) 2 0 .20 - < 0.01 1.00E00 1.00E00 viral release from host cell (GO:0019076) 9 0 .89 - < 0.01 1.00E00 1.00E00 virus maturation (GO:0019075) 2 0 .20 - < 0.01 1.00E00 1.00E00 asparagine catabolic process via L-aspartate (GO:0033345) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of collagen binding (GO:0033343) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of retrograde axon cargo transport (GO:2001019) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of collagen binding (GO:0033342) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of collagen binding (GO:0033341) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of retrograde axon cargo transport (GO:2001017) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of skeletal muscle cell differentiation (GO:2001015) 4 0 .40 - < 0.01 1.00E00 1.00E00 adenosine 5'-(hexahydrogen pentaphosphate) catabolic process (GO:1901911) 4 0 .40 - < 0.01 1.00E00 1.00E00 epithelial cell proliferation involved in renal tubule morphogenesis (GO:2001013) 4 0 .40 - < 0.01 1.00E00 1.00E00 adenosine 5'-(hexahydrogen pentaphosphate) metabolic process (GO:1901910) 4 0 .40 - < 0.01 1.00E00 1.00E00 mesenchymal cell differentiation involved in renal system development (GO:2001012) 3 0 .30 - < 0.01 1.00E00 1.00E00 receptor-mediated endocytosis of virus by host cell (GO:0019065) 6 0 .59 - < 0.01 1.00E00 1.00E00 centriole replication (GO:0007099) 22 0 2.18 - < 0.01 2.56E-01 1.00E00 metaphase/anaphase transition of mitotic cell cycle (GO:0007091) 9 0 .89 - < 0.01 1.00E00 1.00E00 diadenosine hexaphosphate catabolic process (GO:1901909) 4 0 .40 - < 0.01 1.00E00 1.00E00 diadenosine hexaphosphate metabolic process (GO:1901908) 4 0 .40 - < 0.01 1.00E00 1.00E00 diadenosine pentaphosphate catabolic process (GO:1901907) 4 0 .40 - < 0.01 1.00E00 1.00E00 diadenosine pentaphosphate metabolic process (GO:1901906) 4 0 .40 - < 0.01 1.00E00 1.00E00 B cell apoptotic process (GO:0001783) 8 0 .79 - < 0.01 1.00E00 1.00E00 traversing start control point of mitotic cell cycle (GO:0007089) 3 0 .30 - < 0.01 1.00E00 1.00E00 mitotic nuclear membrane reassembly (GO:0007084) 3 0 .30 - < 0.01 1.00E00 1.00E00 Leydig cell differentiation (GO:0033327) 9 0 .89 - < 0.01 1.00E00 1.00E00 cerebrospinal fluid secretion (GO:0033326) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitotic metaphase plate congression (GO:0007080) 42 0 4.15 - < 0.01 3.00E-02 4.48E-01 T cell homeostatic proliferation (GO:0001777) 1 0 .10 - < 0.01 1.00E00 1.00E00 telomere maintenance via telomere trimming (GO:0090737) 5 0 .49 - < 0.01 1.00E00 1.00E00 mitotic chromosome movement towards spindle pole (GO:0007079) 2 0 .20 - < 0.01 1.00E00 1.00E00 immunological synapse formation (GO:0001771) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 mitotic chromosome condensation (GO:0007076) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 positive regulation of transcription involved in exit from mitosis (GO:0007072) 1 0 .10 - < 0.01 1.00E00 1.00E00 meiotic spindle assembly checkpoint signaling (GO:0033316) 1 0 .10 - < 0.01 1.00E00 1.00E00 meiotic cell cycle checkpoint signaling (GO:0033313) 7 0 .69 - < 0.01 1.00E00 1.00E00 anterior/posterior pattern specification involved in ureteric bud development (GO:0072099) 1 0 .10 - < 0.01 1.00E00 1.00E00 anterior/posterior pattern specification involved in kidney development (GO:0072098) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway (GO:0072097) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of branch elongation involved in ureteric bud branching (GO:0072096) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of branch elongation involved in ureteric bud branching (GO:0072095) 3 0 .30 - < 0.01 1.00E00 1.00E00 ascorbate homeostasis (GO:0140576) 3 0 .30 - < 0.01 1.00E00 1.00E00 establishment of T cell polarity (GO:0001768) 7 0 .69 - < 0.01 1.00E00 1.00E00 establishment of lymphocyte polarity (GO:0001767) 7 0 .69 - < 0.01 1.00E00 1.00E00 metanephric renal vesicle formation (GO:0072093) 3 0 .30 - < 0.01 1.00E00 1.00E00 membrane raft polarization (GO:0001766) 1 0 .10 - < 0.01 1.00E00 1.00E00 ureteric bud invasion (GO:0072092) 2 0 .20 - < 0.01 1.00E00 1.00E00 membrane raft assembly (GO:0001765) 10 0 .99 - < 0.01 1.00E00 1.00E00 regulation of stem cell proliferation (GO:0072091) 40 0 3.95 - < 0.01 4.70E-02 5.81E-01 extraction of mislocalized protein from mitochondrial outer membrane (GO:0140570) 1 0 .10 - < 0.01 1.00E00 1.00E00 beta-alanine transport (GO:0001762) 1 0 .10 - < 0.01 1.00E00 1.00E00 primary adaptive immune response involving T cells and B cells (GO:0090721) 1 0 .10 - < 0.01 1.00E00 1.00E00 primary adaptive immune response (GO:0090720) 1 0 .10 - < 0.01 1.00E00 1.00E00 phytol metabolic process (GO:0033306) 2 0 .20 - < 0.01 1.00E00 1.00E00 cell cycle comprising mitosis without cytokinesis (GO:0033301) 1 0 .10 - < 0.01 1.00E00 1.00E00 extraction of mislocalized protein from ER membrane (GO:0140569) 1 0 .10 - < 0.01 1.00E00 1.00E00 renal vesicle development (GO:0072087) 8 0 .79 - < 0.01 1.00E00 1.00E00 extraction of mislocalized protein from membrane (GO:0140568) 2 0 .20 - < 0.01 1.00E00 1.00E00 specification of loop of Henle identity (GO:0072086) 1 0 .10 - < 0.01 1.00E00 1.00E00 organ induction (GO:0001759) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 somite specification (GO:0001757) 2 0 .20 - < 0.01 1.00E00 1.00E00 specification of nephron tubule identity (GO:0072081) 1 0 .10 - < 0.01 1.00E00 1.00E00 immunological memory formation process (GO:0090715) 2 0 .20 - < 0.01 1.00E00 1.00E00 immunological memory process (GO:0090713) 2 0 .20 - < 0.01 1.00E00 1.00E00 spindle assembly involved in female meiosis I (GO:0007057) 5 0 .49 - < 0.01 1.00E00 1.00E00 nephron tubule formation (GO:0072079) 10 0 .99 - < 0.01 1.00E00 1.00E00 renal vesicle morphogenesis (GO:0072077) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of metanephric DCT cell differentiation (GO:2000594) 1 0 .10 - < 0.01 1.00E00 1.00E00 nephrogenic mesenchyme development (GO:0072076) 3 0 .30 - < 0.01 1.00E00 1.00E00 metanephric mesenchyme development (GO:0072075) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of metanephric DCT cell differentiation (GO:2000592) 1 0 .10 - < 0.01 1.00E00 1.00E00 kidney mesenchyme development (GO:0072074) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of metanephric mesenchymal cell migration (GO:2000591) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of metanephric mesenchymal cell migration (GO:2000590) 1 0 .10 - < 0.01 1.00E00 1.00E00 optic placode formation (GO:0001743) 2 0 .20 - < 0.01 1.00E00 1.00E00 lysosomal lumen acidification (GO:0007042) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 regulation of metanephric mesenchymal cell migration (GO:2000589) 4 0 .40 - < 0.01 1.00E00 1.00E00 DCT cell differentiation (GO:0072069) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of platelet-derived growth factor receptor-alpha signaling pathway (GO:2000584) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of platelet-derived growth factor receptor-alpha signaling pathway (GO:2000583) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of ATP-dependent microtubule motor activity, plus-end-directed (GO:2000582) 3 0 .30 - < 0.01 1.00E00 1.00E00 morphogenesis of a polarized epithelium (GO:0001738) 45 0 4.45 - < 0.01 3.15E-02 4.60E-01 regulation of ATP-dependent microtubule motor activity, plus-end-directed (GO:2000580) 3 0 .30 - < 0.01 1.00E00 1.00E00 establishment of planar polarity (GO:0001736) 22 0 2.18 - < 0.01 2.56E-01 1.00E00 inner medullary collecting duct development (GO:0072061) 2 0 .20 - < 0.01 1.00E00 1.00E00 formation of cytoplasmic translation initiation complex (GO:0001732) 4 0 .40 - < 0.01 1.00E00 1.00E00 formation of translation preinitiation complex (GO:0001731) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 mitotic cytokinesis checkpoint signaling (GO:0044878) 3 0 .30 - < 0.01 1.00E00 1.00E00 serotonin secretion, neurotransmission (GO:0060096) 1 0 .10 - < 0.01 1.00E00 1.00E00 lipoprotein localization to membrane (GO:0044873) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation by host of viral glycoprotein metabolic process (GO:0044871) 1 0 .10 - < 0.01 1.00E00 1.00E00 modulation by host of viral glycoprotein metabolic process (GO:0044870) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of ATP-dependent microtubule motor activity, minus-end-directed (GO:2000578) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of ATP-dependent microtubule motor activity, minus-end-directed (GO:2000577) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of microtubule motor activity (GO:2000576) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of microtubule motor activity (GO:2000575) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of microtubule motor activity (GO:2000574) 9 0 .89 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-4-dependent isotype switching to IgE isotypes (GO:2000572) 1 0 .10 - < 0.01 1.00E00 1.00E00 renal outer medulla development (GO:0072054) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of interleukin-4-dependent isotype switching to IgE isotypes (GO:2000571) 1 0 .10 - < 0.01 1.00E00 1.00E00 renal inner medulla development (GO:0072053) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of T-helper 2 cell activation (GO:2000570) 2 0 .20 - < 0.01 1.00E00 1.00E00 juxtaglomerular apparatus development (GO:0072051) 1 0 .10 - < 0.01 1.00E00 1.00E00 auditory receptor cell stereocilium organization (GO:0060088) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 negative regulation by host of viral exo-alpha-sialidase activity (GO:0044869) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of microtubule depolymerization (GO:0007026) 31 0 3.07 - < 0.01 1.09E-01 9.08E-01 modulation by host of viral molecular function (GO:0044868) 2 0 .20 - < 0.01 1.00E00 1.00E00 modulation by host of viral catalytic activity (GO:0044867) 1 0 .10 - < 0.01 1.00E00 1.00E00 modulation by host of viral exo-alpha-sialidase activity (GO:0044866) 1 0 .10 - < 0.01 1.00E00 1.00E00 synaptic transmission involved in micturition (GO:0060084) 1 0 .10 - < 0.01 1.00E00 1.00E00 smooth muscle contraction involved in micturition (GO:0060083) 2 0 .20 - < 0.01 1.00E00 1.00E00 modulation by host of symbiont transcription (GO:0052472) 2 0 .20 - < 0.01 1.00E00 1.00E00 microtubule nucleation (GO:0007020) 20 0 1.98 - < 0.01 2.51E-01 1.00E00 inhibitory postsynaptic potential (GO:0060080) 4 0 .40 - < 0.01 1.00E00 1.00E00 protein transport into plasma membrane raft (GO:0044861) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein localization to plasma membrane raft (GO:0044860) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of neurotrophin production (GO:0032899) 2 0 .20 - < 0.01 1.00E00 1.00E00 neurotrophin production (GO:0032898) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of T-helper 2 cell activation (GO:2000569) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of memory T cell activation (GO:2000568) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of memory T cell activation (GO:2000567) 2 0 .20 - < 0.01 1.00E00 1.00E00 renal system pattern specification (GO:0072048) 4 0 .40 - < 0.01 1.00E00 1.00E00 thyroid-stimulating hormone signaling pathway (GO:0038194) 1 0 .10 - < 0.01 1.00E00 1.00E00 proximal/distal pattern formation involved in nephron development (GO:0072047) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of CD24 production (GO:2000560) 1 0 .10 - < 0.01 1.00E00 1.00E00 endodermal cell fate specification (GO:0001714) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis (GO:0072040) 2 0 .20 - < 0.01 1.00E00 1.00E00 ectodermal cell fate commitment (GO:0001712) 2 0 .20 - < 0.01 1.00E00 1.00E00 endodermal cell fate commitment (GO:0001711) 8 0 .79 - < 0.01 1.00E00 1.00E00 plasma membrane raft organization (GO:0044857) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of resting membrane potential (GO:0060075) 7 0 .69 - < 0.01 1.00E00 1.00E00 actin ubiquitination (GO:0007014) 1 0 .10 - < 0.01 1.00E00 1.00E00 plasma membrane raft localization (GO:0044856) 1 0 .10 - < 0.01 1.00E00 1.00E00 plasma membrane raft distribution (GO:0044855) 1 0 .10 - < 0.01 1.00E00 1.00E00 micturition (GO:0060073) 4 0 .40 - < 0.01 1.00E00 1.00E00 plasma membrane raft assembly (GO:0044854) 4 0 .40 - < 0.01 1.00E00 1.00E00 Wnt signaling pathway, planar cell polarity pathway (GO:0060071) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 regulation of vacuole fusion, non-autophagic (GO:0032889) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of mitotic spindle elongation (GO:0032888) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of spindle elongation (GO:0032887) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of CD24 production (GO:2000559) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of immunoglobulin production in mucosal tissue (GO:2000558) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of immunoglobulin production in mucosal tissue (GO:2000557) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis (GO:0072039) 2 0 .20 - < 0.01 1.00E00 1.00E00 cell surface bile acid receptor signaling pathway (GO:0038184) 1 0 .10 - < 0.01 1.00E00 1.00E00 bile acid signaling pathway (GO:0038183) 2 0 .20 - < 0.01 1.00E00 1.00E00 mesenchymal to epithelial transition involved in renal vesicle formation (GO:0072036) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell fate determination (GO:0001709) 26 0 2.57 - < 0.01 1.65E-01 1.00E00 negative regulation of T-helper 2 cell cytokine production (GO:2000552) 2 0 .20 - < 0.01 1.00E00 1.00E00 renal vesicle induction (GO:0072034) 3 0 .30 - < 0.01 1.00E00 1.00E00 renal vesicle formation (GO:0072033) 5 0 .49 - < 0.01 1.00E00 1.00E00 ectoderm formation (GO:0001705) 2 0 .20 - < 0.01 1.00E00 1.00E00 outer mitochondrial membrane organization (GO:0007008) 5 0 .49 - < 0.01 1.00E00 1.00E00 telomere maintenance via telomerase (GO:0007004) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 nucleolus organization (GO:0007000) 8 0 .79 - < 0.01 1.00E00 1.00E00 post-embryonic retina morphogenesis in camera-type eye (GO:0060060) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of DNA endoreduplication (GO:0032877) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of DNA endoreduplication (GO:0032876) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of DNA endoreduplication (GO:0032875) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of dendritic cell dendrite assembly (GO:2000547) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of endothelial cell chemotaxis to fibroblast growth factor (GO:2000546) 3 0 .30 - < 0.01 1.00E00 1.00E00 connecting tubule development (GO:0072027) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of endothelial cell chemotaxis to fibroblast growth factor (GO:2000544) 4 0 .40 - < 0.01 1.00E00 1.00E00 interleukin-17A-mediated signaling pathway (GO:0038173) 1 0 .10 - < 0.01 1.00E00 1.00E00 granzyme-mediated programmed cell death signaling pathway (GO:0140507) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of gastrulation (GO:2000543) 2 0 .20 - < 0.01 1.00E00 1.00E00 interleukin-33-mediated signaling pathway (GO:0038172) 1 0 .10 - < 0.01 1.00E00 1.00E00 distal convoluted tubule development (GO:0072025) 3 0 .30 - < 0.01 1.00E00 1.00E00 macula densa development (GO:0072024) 1 0 .10 - < 0.01 1.00E00 1.00E00 thick ascending limb development (GO:0072023) 1 0 .10 - < 0.01 1.00E00 1.00E00 ascending thin limb development (GO:0072021) 1 0 .10 - < 0.01 1.00E00 1.00E00 embryonic retina morphogenesis in camera-type eye (GO:0060059) 5 0 .49 - < 0.01 1.00E00 1.00E00 ceramide 1-phosphate transport (GO:1902389) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of apoptotic process involved in mammary gland involution (GO:0060058) 4 0 .40 - < 0.01 1.00E00 1.00E00 cell quiescence (GO:0044838) 3 0 .30 - < 0.01 1.00E00 1.00E00 mammary gland involution (GO:0060056) 4 0 .40 - < 0.01 1.00E00 1.00E00 actomyosin contractile ring organization (GO:0044837) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of epithelial cell proliferation involved in wound healing (GO:0060054) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of protein glycosylation (GO:0060051) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of protein glycosylation (GO:0060050) 7 0 .69 - < 0.01 1.00E00 1.00E00 modulation by host of viral RNA genome replication (GO:0044830) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of B cell chemotaxis (GO:2000538) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of B cell chemotaxis (GO:2000537) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of entry of bacterium into host cell (GO:2000536) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of entry of bacterium into host cell (GO:2000535) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of renal albumin absorption (GO:2000534) 1 0 .10 - < 0.01 1.00E00 1.00E00 thrombopoietin-mediated signaling pathway (GO:0038163) 4 0 .40 - < 0.01 1.00E00 1.00E00 erythropoietin-mediated signaling pathway (GO:0038162) 1 0 .10 - < 0.01 1.00E00 1.00E00 glomerular visceral epithelial cell development (GO:0072015) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of renal albumin absorption (GO:2000532) 1 0 .10 - < 0.01 1.00E00 1.00E00 prolactin signaling pathway (GO:0038161) 1 0 .10 - < 0.01 1.00E00 1.00E00 CXCL12-activated CXCR4 signaling pathway (GO:0038160) 2 0 .20 - < 0.01 1.00E00 1.00E00 glomerular endothelium development (GO:0072011) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein glycosylation (GO:0060049) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 positive regulation by host of viral genome replication (GO:0044829) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of acrosome reaction (GO:0060046) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of rRNA catabolic process (GO:1902374) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of tRNA catabolic process (GO:1902371) 2 0 .20 - < 0.01 1.00E00 1.00E00 retinal bipolar neuron differentiation (GO:0060040) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of tRNA catabolic process (GO:1902370) 2 0 .20 - < 0.01 1.00E00 1.00E00 meiotic telomere tethering at nuclear periphery (GO:0044821) 2 0 .20 - < 0.01 1.00E00 1.00E00 C-X-C chemokine receptor CXCR4 signaling pathway (GO:0038159) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation (GO:2000526) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of T cell costimulation (GO:2000525) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of T cell costimulation (GO:2000524) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of T cell costimulation (GO:2000523) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of immunological synapse formation (GO:2000522) 2 0 .20 - < 0.01 1.00E00 1.00E00 kidney field specification (GO:0072004) 1 0 .10 - < 0.01 1.00E00 1.00E00 kidney rudiment formation (GO:0072003) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitotic G1/S transition checkpoint signaling (GO:0044819) 23 0 2.27 - < 0.01 2.61E-01 1.00E00 modulation by host of symbiont molecular function (GO:0052428) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of Notch signaling pathway involved in somitogenesis (GO:1902367) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of Notch signaling pathway involved in somitogenesis (GO:1902366) 2 0 .20 - < 0.01 1.00E00 1.00E00 notochord cell development (GO:0060035) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to spindle pole body (GO:1902365) 1 0 .10 - < 0.01 1.00E00 1.00E00 notochord cell differentiation (GO:0060034) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein localization to spindle pole body (GO:1902363) 1 0 .10 - < 0.01 1.00E00 1.00E00 modulation by host of symbiont catalytic activity (GO:0052422) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of cellular pH reduction (GO:0032849) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of T-helper 1 cell activation (GO:2000518) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of T-helper 1 cell activation (GO:2000517) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of granzyme A production (GO:2000513) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of granzyme A production (GO:2000511) 1 0 .10 - < 0.01 1.00E00 1.00E00 convergent extension involved in organogenesis (GO:0060029) 4 0 .40 - < 0.01 1.00E00 1.00E00 metabolism by host of substance in symbiont (GO:0052419) 2 0 .20 - < 0.01 1.00E00 1.00E00 convergent extension involved in axis elongation (GO:0060028) 5 0 .49 - < 0.01 1.00E00 1.00E00 sulfate transmembrane transport (GO:1902358) 1 0 .10 - < 0.01 1.00E00 1.00E00 metabolism by organism of protein in other organism involved in symbiotic interaction (GO:0052418) 1 0 .10 - < 0.01 1.00E00 1.00E00 convergent extension involved in gastrulation (GO:0060027) 5 0 .49 - < 0.01 1.00E00 1.00E00 metabolism by host of symbiont protein (GO:0052417) 1 0 .10 - < 0.01 1.00E00 1.00E00 convergent extension (GO:0060026) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 metabolism by host of symbiont macromolecule (GO:0052416) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of synaptic activity (GO:0060025) 2 0 .20 - < 0.01 1.00E00 1.00E00 G-quadruplex DNA unwinding (GO:0044806) 6 0 .59 - < 0.01 1.00E00 1.00E00 rhythmic synaptic transmission (GO:0060024) 5 0 .49 - < 0.01 1.00E00 1.00E00 metabolism by organism of cell wall chitin in other organism involved in symbiotic interaction (GO:0052411) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to chloroquine (GO:1902350) 1 0 .10 - < 0.01 1.00E00 1.00E00 metabolism by host of symbiont cell wall chitin (GO:0052410) 1 0 .10 - < 0.01 1.00E00 1.00E00 ornithine biosynthetic process (GO:0006592) 1 0 .10 - < 0.01 1.00E00 1.00E00 ornithine metabolic process (GO:0006591) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response (GO:0032834) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of dendritic cell chemotaxis (GO:2000509) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response (GO:0032832) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation (GO:0032831) 3 0 .30 - < 0.01 1.00E00 1.00E00 response to chloroquine (GO:1902349) 1 0 .10 - < 0.01 1.00E00 1.00E00 astrocyte fate commitment (GO:0060018) 3 0 .30 - < 0.01 1.00E00 1.00E00 parathyroid gland development (GO:0060017) 5 0 .49 - < 0.01 1.00E00 1.00E00 metabolism by organism of carbohydrate in other organism involved in symbiotic interaction (GO:0052407) 1 0 .10 - < 0.01 1.00E00 1.00E00 granulosa cell development (GO:0060016) 1 0 .10 - < 0.01 1.00E00 1.00E00 metabolism by host of symbiont carbohydrate (GO:0052406) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation by host of symbiont molecular function (GO:0052405) 3 0 .30 - < 0.01 1.00E00 1.00E00 granulosa cell differentiation (GO:0060014) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation by host of symbiont catalytic activity (GO:0052403) 1 0 .10 - < 0.01 1.00E00 1.00E00 Sertoli cell proliferation (GO:0060011) 5 0 .49 - < 0.01 1.00E00 1.00E00 Sertoli cell fate commitment (GO:0060010) 1 0 .10 - < 0.01 1.00E00 1.00E00 serotonin biosynthetic process from tryptophan (GO:0006587) 2 0 .20 - < 0.01 1.00E00 1.00E00 ethanolamine metabolic process (GO:0006580) 2 0 .20 - < 0.01 1.00E00 1.00E00 toll-like receptor TLR1:TLR2 signaling pathway (GO:0038123) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of apoptotic process involved in morphogenesis (GO:1902338) 4 0 .40 - < 0.01 1.00E00 1.00E00 linear vestibuloocular reflex (GO:0060007) 1 0 .10 - < 0.01 1.00E00 1.00E00 vestibular reflex (GO:0060005) 4 0 .40 - < 0.01 1.00E00 1.00E00 amino-acid betaine catabolic process (GO:0006579) 1 0 .10 - < 0.01 1.00E00 1.00E00 valine catabolic process (GO:0006574) 4 0 .40 - < 0.01 1.00E00 1.00E00 valine metabolic process (GO:0006573) 7 0 .69 - < 0.01 1.00E00 1.00E00 tyrosine catabolic process (GO:0006572) 3 0 .30 - < 0.01 1.00E00 1.00E00 tyrosine metabolic process (GO:0006570) 6 0 .59 - < 0.01 1.00E00 1.00E00 chemokine (C-C motif) ligand 21 signaling pathway (GO:0038116) 2 0 .20 - < 0.01 1.00E00 1.00E00 interleukin-2-mediated signaling pathway (GO:0038110) 2 0 .20 - < 0.01 1.00E00 1.00E00 ubiquitin-dependent protein catabolic process via the N-end rule pathway (GO:0071596) 3 0 .30 - < 0.01 1.00E00 1.00E00 thymocyte aggregation (GO:0071594) 1 0 .10 - < 0.01 1.00E00 1.00E00 lymphocyte aggregation (GO:0071593) 5 0 .49 - < 0.01 1.00E00 1.00E00 threonine catabolic process (GO:0006567) 3 0 .30 - < 0.01 1.00E00 1.00E00 threonine metabolic process (GO:0006566) 4 0 .40 - < 0.01 1.00E00 1.00E00 L-serine catabolic process (GO:0006565) 2 0 .20 - < 0.01 1.00E00 1.00E00 L-serine biosynthetic process (GO:0006564) 4 0 .40 - < 0.01 1.00E00 1.00E00 L-serine metabolic process (GO:0006563) 7 0 .69 - < 0.01 1.00E00 1.00E00 proline catabolic process (GO:0006562) 2 0 .20 - < 0.01 1.00E00 1.00E00 proline biosynthetic process (GO:0006561) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of low-density lipoprotein particle receptor catabolic process (GO:0032805) 3 0 .30 - < 0.01 1.00E00 1.00E00 proline metabolic process (GO:0006560) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of low-density lipoprotein particle receptor catabolic process (GO:0032804) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of low-density lipoprotein particle receptor catabolic process (GO:0032803) 6 0 .59 - < 0.01 1.00E00 1.00E00 Kit signaling pathway (GO:0038109) 2 0 .20 - < 0.01 1.00E00 1.00E00 low-density lipoprotein particle receptor catabolic process (GO:0032802) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of appetite by leptin-mediated signaling pathway (GO:0038108) 3 0 .30 - < 0.01 1.00E00 1.00E00 nodal signaling pathway involved in determination of left/right asymmetry (GO:0038107) 3 0 .30 - < 0.01 1.00E00 1.00E00 sequestering of nodal from receptor via nodal binding (GO:0038101) 1 0 .10 - < 0.01 1.00E00 1.00E00 DNA strand elongation involved in nuclear cell cycle DNA replication (GO:1902319) 1 0 .10 - < 0.01 1.00E00 1.00E00 CAAX-box protein processing (GO:0071586) 2 0 .20 - < 0.01 1.00E00 1.00E00 nuclear DNA replication termination (GO:1902317) 1 0 .10 - < 0.01 1.00E00 1.00E00 L-phenylalanine catabolic process (GO:0006559) 4 0 .40 - < 0.01 1.00E00 1.00E00 L-phenylalanine metabolic process (GO:0006558) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of peptidyl-serine dephosphorylation (GO:1902310) 1 0 .10 - < 0.01 1.00E00 1.00E00 S-adenosylmethionine biosynthetic process (GO:0006556) 4 0 .40 - < 0.01 1.00E00 1.00E00 methionine metabolic process (GO:0006555) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 lysine catabolic process (GO:0006554) 1 0 .10 - < 0.01 1.00E00 1.00E00 lysine metabolic process (GO:0006553) 2 0 .20 - < 0.01 1.00E00 1.00E00 leucine catabolic process (GO:0006552) 5 0 .49 - < 0.01 1.00E00 1.00E00 leucine metabolic process (GO:0006551) 7 0 .69 - < 0.01 1.00E00 1.00E00 isoleucine catabolic process (GO:0006550) 5 0 .49 - < 0.01 1.00E00 1.00E00 hepatocyte cell migration (GO:0002194) 1 0 .10 - < 0.01 1.00E00 1.00E00 IRES-dependent translational initiation of linear mRNA (GO:0002192) 2 0 .20 - < 0.01 1.00E00 1.00E00 cap-dependent translational initiation (GO:0002191) 1 0 .10 - < 0.01 1.00E00 1.00E00 cap-independent translational initiation (GO:0002190) 2 0 .20 - < 0.01 1.00E00 1.00E00 zinc ion import across plasma membrane (GO:0071578) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of peptidyl-serine dephosphorylation (GO:1902309) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of peptidyl-serine dephosphorylation (GO:1902308) 4 0 .40 - < 0.01 1.00E00 1.00E00 isoleucine metabolic process (GO:0006549) 7 0 .69 - < 0.01 1.00E00 1.00E00 glycine catabolic process (GO:0006546) 3 0 .30 - < 0.01 1.00E00 1.00E00 glycine biosynthetic process (GO:0006545) 5 0 .49 - < 0.01 1.00E00 1.00E00 glycine metabolic process (GO:0006544) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 glutamine catabolic process (GO:0006543) 3 0 .30 - < 0.01 1.00E00 1.00E00 glutamine biosynthetic process (GO:0006542) 1 0 .10 - < 0.01 1.00E00 1.00E00 glutamate decarboxylation to succinate (GO:0006540) 1 0 .10 - < 0.01 1.00E00 1.00E00 translation reinitiation (GO:0002188) 4 0 .40 - < 0.01 1.00E00 1.00E00 cytoplasmic translational initiation (GO:0002183) 21 0 2.08 - < 0.01 2.52E-01 1.00E00 cytoplasmic translational elongation (GO:0002182) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein ufmylation (GO:0071569) 6 0 .59 - < 0.01 1.00E00 1.00E00 glutamate biosynthetic process (GO:0006537) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of attachment of spindle microtubules to kinetochore (GO:0051988) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 positive regulation of attachment of spindle microtubules to kinetochore (GO:0051987) 7 0 .69 - < 0.01 1.00E00 1.00E00 cysteine biosynthetic process from serine (GO:0006535) 1 0 .10 - < 0.01 1.00E00 1.00E00 aspartate catabolic process (GO:0006533) 2 0 .20 - < 0.01 1.00E00 1.00E00 RNA acetylation (GO:1990884) 1 0 .10 - < 0.01 1.00E00 1.00E00 aspartate biosynthetic process (GO:0006532) 2 0 .20 - < 0.01 1.00E00 1.00E00 aspartate metabolic process (GO:0006531) 3 0 .30 - < 0.01 1.00E00 1.00E00 rRNA acetylation (GO:1990882) 1 0 .10 - < 0.01 1.00E00 1.00E00 asparagine catabolic process (GO:0006530) 1 0 .10 - < 0.01 1.00E00 1.00E00 male germ cell proliferation (GO:0002176) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell wall organization or biogenesis (GO:0071554) 2 0 .20 - < 0.01 1.00E00 1.00E00 death-inducing signaling complex assembly (GO:0071550) 2 0 .20 - < 0.01 1.00E00 1.00E00 asparagine biosynthetic process (GO:0006529) 1 0 .10 - < 0.01 1.00E00 1.00E00 arginine catabolic process (GO:0006527) 8 0 .79 - < 0.01 1.00E00 1.00E00 arginine biosynthetic process (GO:0006526) 3 0 .30 - < 0.01 1.00E00 1.00E00 lysophospholipid transport (GO:0051977) 1 0 .10 - < 0.01 1.00E00 1.00E00 arginine metabolic process (GO:0006525) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 alanine catabolic process (GO:0006524) 1 0 .10 - < 0.01 1.00E00 1.00E00 alanine metabolic process (GO:0006522) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of telomerase activity (GO:0051973) 31 0 3.07 - < 0.01 1.09E-01 9.07E-01 regulation of cellular amino acid metabolic process (GO:0006521) 9 0 .89 - < 0.01 1.00E00 1.00E00 diphosphoinositol polyphosphate catabolic process (GO:0071544) 1 0 .10 - < 0.01 1.00E00 1.00E00 diphosphoinositol polyphosphate metabolic process (GO:0071543) 4 0 .40 - < 0.01 1.00E00 1.00E00 protein deglycosylation (GO:0006517) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 negative regulation of synaptic transmission, glutamatergic (GO:0051967) 5 0 .49 - < 0.01 1.00E00 1.00E00 protein quality control for misfolded or incompletely synthesized proteins (GO:0006515) 29 0 2.87 - < 0.01 1.06E-01 8.96E-01 desmosome assembly (GO:0002159) 4 0 .40 - < 0.01 1.00E00 1.00E00 osteoclast proliferation (GO:0002158) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of thyroid hormone mediated signaling pathway (GO:0002155) 5 0 .49 - < 0.01 1.00E00 1.00E00 thyroid hormone mediated signaling pathway (GO:0002154) 3 0 .30 - < 0.01 1.00E00 1.00E00 bile acid conjugation (GO:0002152) 1 0 .10 - < 0.01 1.00E00 1.00E00 otolith mineralization (GO:0045299) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein localization to centrosome (GO:0071539) 24 0 2.37 - < 0.01 1.63E-01 1.00E00 mRNA cis splicing, via spliceosome (GO:0045292) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 positive regulation of relaxation of cardiac muscle (GO:1901899) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to endothelin (GO:1990859) 2 0 .20 - < 0.01 1.00E00 1.00E00 GPI anchor release (GO:0006507) 1 0 .10 - < 0.01 1.00E00 1.00E00 methotrexate transport (GO:0051958) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of ATPase-coupled calcium transmembrane transporter activity (GO:1901896) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of ATPase-coupled calcium transmembrane transporter activity (GO:1901895) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of ATPase-coupled calcium transmembrane transporter activity (GO:1901894) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of glutamate uptake involved in transmission of nerve impulse (GO:0051951) 1 0 .10 - < 0.01 1.00E00 1.00E00 cementum mineralization (GO:0071529) 1 0 .10 - < 0.01 1.00E00 1.00E00 tRNA re-export from nucleus (GO:0071528) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of glutamate uptake involved in transmission of nerve impulse (GO:0051946) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of catecholamine uptake involved in synaptic transmission (GO:0051944) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of amino acid uptake involved in synaptic transmission (GO:0051943) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of protein depolymerization (GO:1901881) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 regulation of amino acid uptake involved in synaptic transmission (GO:0051941) 2 0 .20 - < 0.01 1.00E00 1.00E00 maintenance of imprinting at mating-type locus (GO:0071517) 2 0 .20 - < 0.01 1.00E00 1.00E00 establishment of imprinting at mating-type locus (GO:0071516) 1 0 .10 - < 0.01 1.00E00 1.00E00 genetic imprinting at mating-type locus (GO:0071515) 3 0 .30 - < 0.01 1.00E00 1.00E00 genetic imprinting (GO:0071514) 22 0 2.18 - < 0.01 2.56E-01 1.00E00 gamma-aminobutyric acid import (GO:0051939) 4 0 .40 - < 0.01 1.00E00 1.00E00 response to endothelin (GO:1990839) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of calcium ion binding (GO:1901877) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of calcium ion binding (GO:1901876) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of post-translational protein modification (GO:1901874) 3 0 .30 - < 0.01 1.00E00 1.00E00 catecholamine uptake involved in synaptic transmission (GO:0051934) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of post-translational protein modification (GO:1901873) 4 0 .40 - < 0.01 1.00E00 1.00E00 response to odorant (GO:1990834) 1 0 .10 - < 0.01 1.00E00 1.00E00 slow axonal transport (GO:1990832) 1 0 .10 - < 0.01 1.00E00 1.00E00 tRNA wobble base cytosine methylation (GO:0002127) 1 0 .10 - < 0.01 1.00E00 1.00E00 maternal aggressive behavior (GO:0002125) 1 0 .10 - < 0.01 1.00E00 1.00E00 territorial aggressive behavior (GO:0002124) 1 0 .10 - < 0.01 1.00E00 1.00E00 inter-male aggressive behavior (GO:0002121) 3 0 .30 - < 0.01 1.00E00 1.00E00 secretion of lysosomal enzymes (GO:0033299) 7 0 .69 - < 0.01 1.00E00 1.00E00 cellular response to nitrosative stress (GO:0071500) 4 0 .40 - < 0.01 1.00E00 1.00E00 basic amino acid transmembrane transport (GO:1990822) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial DNA metabolic process (GO:1901860) 1 0 .10 - < 0.01 1.00E00 1.00E00 aggressive behavior (GO:0002118) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial DNA metabolic process (GO:1901859) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of fibrinolysis (GO:0051919) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial DNA metabolic process (GO:1901858) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of cellular respiration (GO:1901856) 9 0 .89 - < 0.01 1.00E00 1.00E00 tRNA wobble cytosine modification (GO:0002101) 2 0 .20 - < 0.01 1.00E00 1.00E00 tRNA wobble adenosine to inosine editing (GO:0002100) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell proliferation in midbrain (GO:0033278) 3 0 .30 - < 0.01 1.00E00 1.00E00 abortive mitotic cell cycle (GO:0033277) 2 0 .20 - < 0.01 1.00E00 1.00E00 actin-myosin filament sliding (GO:0033275) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of cell communication by electrical coupling involved in cardiac conduction (GO:1901845) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cell communication by electrical coupling involved in cardiac conduction (GO:1901844) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of high voltage-gated calcium channel activity (GO:1901843) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial depolarization (GO:0051902) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial depolarization (GO:0051901) 9 0 .89 - < 0.01 1.00E00 1.00E00 protein palmitoleylation (GO:0045234) 1 0 .10 - < 0.01 1.00E00 1.00E00 RNA localization to nucleus (GO:0090685) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I (GO:1901838) 10 0 .99 - < 0.01 1.00E00 1.00E00 negative regulation of transcription of nucleolar large rRNA by RNA polymerase I (GO:1901837) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of nuclear cell cycle DNA replication (GO:0033262) 10 0 .99 - < 0.01 1.00E00 1.00E00 regulation of transcription of nucleolar large rRNA by RNA polymerase I (GO:1901836) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 extracellular polysaccharide biosynthetic process (GO:0045226) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of CD4 production (GO:0045225) 1 0 .10 - < 0.01 1.00E00 1.00E00 calcium ion transmembrane transport via low voltage-gated calcium channel (GO:0090676) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of CD4 production (GO:0045223) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of FasL production (GO:0045221) 1 0 .10 - < 0.01 1.00E00 1.00E00 telomerase RNA localization (GO:0090672) 1 0 .10 - < 0.01 1.00E00 1.00E00 telomerase RNA localization to Cajal body (GO:0090671) 1 0 .10 - < 0.01 1.00E00 1.00E00 RNA localization to Cajal body (GO:0090670) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of FasL production (GO:0045219) 1 0 .10 - < 0.01 1.00E00 1.00E00 zonula adherens maintenance (GO:0045218) 3 0 .30 - < 0.01 1.00E00 1.00E00 telomerase RNA stabilization (GO:0090669) 4 0 .40 - < 0.01 1.00E00 1.00E00 endothelial cell chemotaxis to vascular endothelial growth factor (GO:0090668) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell chemotaxis to vascular endothelial growth factor (GO:0090667) 1 0 .10 - < 0.01 1.00E00 1.00E00 scaRNA localization to Cajal body (GO:0090666) 5 0 .49 - < 0.01 1.00E00 1.00E00 galanin-activated signaling pathway (GO:0090663) 1 0 .10 - < 0.01 1.00E00 1.00E00 FasL biosynthetic process (GO:0045210) 1 0 .10 - < 0.01 1.00E00 1.00E00 cerebrospinal fluid circulation (GO:0090660) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of cellular amine catabolic process (GO:0033242) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cellular amine catabolic process (GO:0033241) 1 0 .10 - < 0.01 1.00E00 1.00E00 beta-carotene metabolic process (GO:1901810) 1 0 .10 - < 0.01 1.00E00 1.00E00 gastrin-induced gastric acid secretion (GO:0001698) 1 0 .10 - < 0.01 1.00E00 1.00E00 histamine-induced gastric acid secretion (GO:0001697) 1 0 .10 - < 0.01 1.00E00 1.00E00 gastric acid secretion (GO:0001696) 4 0 .40 - < 0.01 1.00E00 1.00E00 telomeric loop disassembly (GO:0090657) 8 0 .79 - < 0.01 1.00E00 1.00E00 histamine catabolic process (GO:0001695) 1 0 .10 - < 0.01 1.00E00 1.00E00 t-circle formation (GO:0090656) 5 0 .49 - < 0.01 1.00E00 1.00E00 MAPK export from nucleus (GO:0045204) 1 0 .10 - < 0.01 1.00E00 1.00E00 establishment of neuroblast polarity (GO:0045200) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular response to oxygen-glucose deprivation (GO:0090650) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of protein sumoylation (GO:0033235) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 negative regulation of protein sumoylation (GO:0033234) 8 0 .79 - < 0.01 1.00E00 1.00E00 beta-glucoside catabolic process (GO:1901805) 1 0 .10 - < 0.01 1.00E00 1.00E00 beta-glucoside metabolic process (GO:1901804) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to oxygen-glucose deprivation (GO:0090649) 3 0 .30 - < 0.01 1.00E00 1.00E00 very long-chain fatty acid beta-oxidation (GO:0140493) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial tRNA processing (GO:0090646) 9 0 .89 - < 0.01 1.00E00 1.00E00 tRNA 3'-terminal CCA addition (GO:0001680) 1 0 .10 - < 0.01 1.00E00 1.00E00 dsRNA transport (GO:0033227) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of chromatin assembly or disassembly (GO:0001672) 22 0 2.18 - < 0.01 2.56E-01 1.00E00 mRNA cleavage involved in gene silencing by siRNA (GO:0090625) 1 0 .10 - < 0.01 1.00E00 1.00E00 conditioned taste aversion (GO:0001661) 3 0 .30 - < 0.01 1.00E00 1.00E00 GCN2-mediated signaling (GO:0140469) 2 0 .20 - < 0.01 1.00E00 1.00E00 iron-sulfur cluster export from the mitochondrion (GO:0140466) 1 0 .10 - < 0.01 1.00E00 1.00E00 DNA clamp unloading (GO:0090618) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitochondrial mRNA 3'-end processing (GO:0090616) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial mRNA processing (GO:0090615) 2 0 .20 - < 0.01 1.00E00 1.00E00 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway (GO:0090611) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation by host of viral release from host cell (GO:0044790) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-18-mediated signaling pathway (GO:2000494) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of interleukin-18-mediated signaling pathway (GO:2000492) 1 0 .10 - < 0.01 1.00E00 1.00E00 cytoplasm protein quality control (GO:0140455) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of hepatic stellate cell activation (GO:2000491) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of hepatic stellate cell activation (GO:2000490) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein targeting to Golgi apparatus (GO:0140450) 1 0 .10 - < 0.01 1.00E00 1.00E00 metaphase/anaphase transition of cell cycle (GO:0044784) 9 0 .89 - < 0.01 1.00E00 1.00E00 positive regulation of cAMP-dependent protein kinase activity (GO:2000481) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of cAMP-dependent protein kinase activity (GO:2000480) 8 0 .79 - < 0.01 1.00E00 1.00E00 meiotic spindle checkpoint signaling (GO:0044779) 2 0 .20 - < 0.01 1.00E00 1.00E00 meiotic DNA integrity checkpoint signaling (GO:0044778) 2 0 .20 - < 0.01 1.00E00 1.00E00 meiotic cell cycle phase transition (GO:0044771) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of metanephric glomerular visceral epithelial cell development (GO:2000478) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of metanephric glomerular visceral epithelial cell development (GO:2000477) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of opioid receptor signaling pathway (GO:2000476) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of opioid receptor signaling pathway (GO:2000474) 3 0 .30 - < 0.01 1.00E00 1.00E00 multi-organism transport (GO:0044766) 8 0 .79 - < 0.01 1.00E00 1.00E00 suppression of symbiont entry into host by host (GO:0052373) 1 0 .10 - < 0.01 1.00E00 1.00E00 low-density lipoprotein receptor particle metabolic process (GO:0032799) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of peroxidase activity (GO:2000469) 1 0 .10 - < 0.01 1.00E00 1.00E00 sequestering of BMP from receptor via BMP binding (GO:0038098) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway (GO:0038097) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of glycogen (starch) synthase activity (GO:2000467) 4 0 .40 - < 0.01 1.00E00 1.00E00 ribosome disassembly (GO:0032790) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of glycogen (starch) synthase activity (GO:2000466) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of glycogen (starch) synthase activity (GO:2000465) 7 0 .69 - < 0.01 1.00E00 1.00E00 nodal signaling pathway (GO:0038092) 10 0 .99 - < 0.01 1.00E00 1.00E00 positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway (GO:0038091) 3 0 .30 - < 0.01 1.00E00 1.00E00 disruption by organism of cellular component in other organism involved in symbiotic interaction (GO:0052368) 1 0 .10 - < 0.01 1.00E00 1.00E00 disruption by host of symbiont cellular component (GO:0052367) 1 0 .10 - < 0.01 1.00E00 1.00E00 catabolism by host of substance in symbiont (GO:0052364) 2 0 .20 - < 0.01 1.00E00 1.00E00 catabolism by organism of protein in other organism involved in symbiotic interaction (GO:0052363) 1 0 .10 - < 0.01 1.00E00 1.00E00 catabolism by host of symbiont protein (GO:0052362) 1 0 .10 - < 0.01 1.00E00 1.00E00 catabolism by organism of macromolecule in other organism involved in symbiotic interaction (GO:0052361) 2 0 .20 - < 0.01 1.00E00 1.00E00 catabolism by host of symbiont macromolecule (GO:0052360) 2 0 .20 - < 0.01 1.00E00 1.00E00 unsaturated monocarboxylic acid metabolic process (GO:0032789) 1 0 .10 - < 0.01 1.00E00 1.00E00 saturated monocarboxylic acid metabolic process (GO:0032788) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of DNA-templated transcription, elongation (GO:0032786) 28 0 2.77 - < 0.01 1.73E-01 9.71E-01 negative regulation of DNA-templated transcription, elongation (GO:0032785) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 regulation of DNA-templated transcription, elongation (GO:0032784) 47 0 4.65 - < 0.01 1.98E-02 3.43E-01 positive regulation of cell migration by vascular endothelial growth factor signaling pathway (GO:0038089) 8 0 .79 - < 0.01 1.00E00 1.00E00 VEGF-activated platelet-derived growth factor receptor signaling pathway (GO:0038086) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation (GO:2000454) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation (GO:2000452) 2 0 .20 - < 0.01 1.00E00 1.00E00 cell cycle DNA replication maintenance of fidelity (GO:1902298) 2 0 .20 - < 0.01 1.00E00 1.00E00 DNA strand elongation involved in cell cycle DNA replication (GO:1902296) 1 0 .10 - < 0.01 1.00E00 1.00E00 catabolism by host of symbiont cell wall chitin (GO:0052356) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell cycle DNA replication termination (GO:1902294) 1 0 .10 - < 0.01 1.00E00 1.00E00 catabolism by organism of carbohydrate in other organism involved in symbiotic interaction (GO:0052354) 1 0 .10 - < 0.01 1.00E00 1.00E00 catabolism by host of symbiont carbohydrate (GO:0052353) 1 0 .10 - < 0.01 1.00E00 1.00E00 DNA methylation on cytosine (GO:0032776) 8 0 .79 - < 0.01 1.00E00 1.00E00 DNA methylation on adenine (GO:0032775) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of monophenol monooxygenase activity (GO:0032773) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of monophenol monooxygenase activity (GO:0032771) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of primary amine oxidase activity (GO:1902283) 1 0 .10 - < 0.01 1.00E00 1.00E00 catabolism by organism of cell wall chitin in other organism involved in symbiotic interaction (GO:0052342) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of monocyte extravasation (GO:2000438) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of lymphotoxin A production (GO:0032761) 1 0 .10 - < 0.01 1.00E00 1.00E00 collagen-activated signaling pathway (GO:0038065) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 negative regulation of protein neddylation (GO:2000435) 4 0 .40 - < 0.01 1.00E00 1.00E00 collagen-activated tyrosine kinase receptor signaling pathway (GO:0038063) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 regulation of cytokinesis, actomyosin contractile ring assembly (GO:2000431) 1 0 .10 - < 0.01 1.00E00 1.00E00 disruption by organism of cell wall of other organism involved in symbiotic interaction (GO:0052339) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of pancreatic amylase secretion (GO:1902278) 1 0 .10 - < 0.01 1.00E00 1.00E00 disruption by host of symbiont cell wall (GO:0052338) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of pancreatic amylase secretion (GO:1902277) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of pancreatic amylase secretion (GO:1902276) 2 0 .20 - < 0.01 1.00E00 1.00E00 DNA demethylation of male pronucleus (GO:0044727) 2 0 .20 - < 0.01 1.00E00 1.00E00 modification by host of symbiont cell wall (GO:0052336) 1 0 .10 - < 0.01 1.00E00 1.00E00 chromatin reprogramming in the zygote (GO:0044725) 2 0 .20 - < 0.01 1.00E00 1.00E00 modification by organism of cell wall of other organism involved in symbiotic interaction (GO:0052333) 1 0 .10 - < 0.01 1.00E00 1.00E00 (R)-carnitine transmembrane transport (GO:1902270) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein import into peroxisome matrix, substrate release (GO:0044721) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of TRAIL production (GO:0032759) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of neutrophil aggregation (GO:2000429) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-3 production (GO:0032752) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of neutrophil aggregation (GO:2000428) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of eosinophil extravasation (GO:2000420) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of polyamine transmembrane transport (GO:1902269) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of polyamine transmembrane transport (GO:1902268) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of polyamine transmembrane transport (GO:1902267) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of delayed rectifier potassium channel activity (GO:1902260) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-23 production (GO:0032747) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-21 production (GO:0032745) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of eosinophil extravasation (GO:2000419) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of eosinophil migration (GO:2000417) 2 0 .20 - < 0.01 1.00E00 1.00E00 cross-receptor inhibition within G protein-coupled receptor heterodimer (GO:0038041) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of apoptotic process involved in outflow tract morphogenesis (GO:1902257) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of apoptotic process involved in outflow tract morphogenesis (GO:1902256) 2 0 .20 - < 0.01 1.00E00 1.00E00 N-terminal protein myristoylation (GO:0006499) 4 0 .40 - < 0.01 1.00E00 1.00E00 modulation of transcription in other organism involved in symbiotic interaction (GO:0052312) 2 0 .20 - < 0.01 1.00E00 1.00E00 N-terminal protein lipidation (GO:0006498) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-15 production (GO:0032738) 1 0 .10 - < 0.01 1.00E00 1.00E00 oligosaccharide-lipid intermediate biosynthetic process (GO:0006490) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 negative regulation of T cell extravasation (GO:2000408) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway (GO:0038033) 5 0 .49 - < 0.01 1.00E00 1.00E00 termination of G protein-coupled receptor signaling pathway (GO:0038032) 1 0 .10 - < 0.01 1.00E00 1.00E00 non-canonical Wnt signaling pathway via JNK cascade (GO:0038031) 3 0 .30 - < 0.01 1.00E00 1.00E00 non-canonical Wnt signaling pathway via MAPK cascade (GO:0038030) 4 0 .40 - < 0.01 1.00E00 1.00E00 dolichyl diphosphate biosynthetic process (GO:0006489) 3 0 .30 - < 0.01 1.00E00 1.00E00 dolichol-linked oligosaccharide biosynthetic process (GO:0006488) 10 0 .99 - < 0.01 1.00E00 1.00E00 C-terminal protein methylation (GO:0006481) 3 0 .30 - < 0.01 1.00E00 1.00E00 N-terminal protein amino acid methylation (GO:0006480) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of fractalkine production (GO:0032724) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of connective tissue growth factor production (GO:0032723) 2 0 .20 - < 0.01 1.00E00 1.00E00 epidermal growth factor receptor signaling pathway via MAPK cascade (GO:0038029) 1 0 .10 - < 0.01 1.00E00 1.00E00 insulin receptor signaling pathway via phosphatidylinositol 3-kinase (GO:0038028) 3 0 .30 - < 0.01 1.00E00 1.00E00 apolipoprotein A-I-mediated signaling pathway (GO:0038027) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902237) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of positive thymic T cell selection (GO:1902233) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of positive thymic T cell selection (GO:1902232) 2 0 .20 - < 0.01 1.00E00 1.00E00 peptidyl-tyrosine sulfation (GO:0006478) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein sulfation (GO:0006477) 4 0 .40 - < 0.01 1.00E00 1.00E00 N-terminal protein amino acid acetylation (GO:0006474) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 negative regulation of interleukin-3 production (GO:0032712) 1 0 .10 - < 0.01 1.00E00 1.00E00 Wnt receptor catabolic process (GO:0038018) 2 0 .20 - < 0.01 1.00E00 1.00E00 insulin receptor internalization (GO:0038016) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to freezing (GO:0071497) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage colony-stimulating factor signaling pathway (GO:1902228) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of macrophage colony-stimulating factor signaling pathway (GO:1902227) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular response to UV-C (GO:0071494) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of macrophage colony-stimulating factor signaling pathway (GO:1902226) 4 0 .40 - < 0.01 1.00E00 1.00E00 ketone body metabolic process (GO:1902224) 7 0 .69 - < 0.01 1.00E00 1.00E00 erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) 4 0 .40 - < 0.01 1.00E00 1.00E00 erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress (GO:1902220) 1 0 .10 - < 0.01 1.00E00 1.00E00 steroid hormone receptor complex assembly (GO:0006463) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to isoquinoline alkaloid (GO:0014072) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 negative regulation of interleukin-18 production (GO:0032701) 2 0 .20 - < 0.01 1.00E00 1.00E00 G protein-coupled opioid receptor signaling pathway (GO:0038003) 2 0 .20 - < 0.01 1.00E00 1.00E00 endocrine signaling (GO:0038002) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to red or far red light (GO:0071489) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress (GO:1902219) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to high light intensity (GO:0071486) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress (GO:1902218) 3 0 .30 - < 0.01 1.00E00 1.00E00 peptidyl-glutamic acid poly-ADP-ribosylation (GO:0018424) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to light intensity (GO:0071484) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-4-mediated signaling pathway (GO:1902215) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to X-ray (GO:0071481) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of prolactin signaling pathway (GO:1902213) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of prolactin signaling pathway (GO:1902211) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of serotonin secretion (GO:0014063) 4 0 .40 - < 0.01 1.00E00 1.00E00 translational readthrough (GO:0006451) 6 0 .59 - < 0.01 1.00E00 1.00E00 auditory receptor cell morphogenesis (GO:0002093) 20 0 1.98 - < 0.01 2.51E-01 1.00E00 cellular hypotonic salinity response (GO:0071477) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular hypotonic response (GO:0071476) 7 0 .69 - < 0.01 1.00E00 1.00E00 cellular hyperosmotic salinity response (GO:0071475) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-2-mediated signaling pathway (GO:1902206) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of interleukin-2-mediated signaling pathway (GO:1902205) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of hepatocyte growth factor receptor signaling pathway (GO:1902204) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to non-ionic osmotic stress (GO:0071471) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of hepatocyte growth factor receptor signaling pathway (GO:1902203) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of hepatocyte growth factor receptor signaling pathway (GO:1902202) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of acetylcholine secretion, neurotransmission (GO:0014057) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of translational initiation by iron (GO:0006447) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of acetylcholine secretion, neurotransmission (GO:0014056) 3 0 .30 - < 0.01 1.00E00 1.00E00 gamma-aminobutyric acid secretion (GO:0014051) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of cardioblast differentiation (GO:0051892) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to glial cell derived neurotrophic factor (GO:1990792) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cardioblast differentiation (GO:0051891) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of cardioblast differentiation (GO:0051890) 5 0 .49 - < 0.01 1.00E00 1.00E00 response to glial cell derived neurotrophic factor (GO:1990790) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of respiratory gaseous exchange by nervous system process (GO:0002087) 7 0 .69 - < 0.01 1.00E00 1.00E00 protein depalmitoylation (GO:0002084) 10 0 .99 - < 0.01 1.00E00 1.00E00 cellular response to alkaline pH (GO:0071469) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to acidic pH (GO:0071468) 10 0 .99 - < 0.01 1.00E00 1.00E00 protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan (GO:0018406) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular response to hydrostatic pressure (GO:0071464) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular response to water stimulus (GO:0071462) 4 0 .40 - < 0.01 1.00E00 1.00E00 cellular response to redox state (GO:0071461) 2 0 .20 - < 0.01 1.00E00 1.00E00 peptidyl-proline hydroxylation to 3-hydroxy-L-proline (GO:0018400) 1 0 .10 - < 0.01 1.00E00 1.00E00 glutamate secretion (GO:0014047) 6 0 .59 - < 0.01 1.00E00 1.00E00 tryptophanyl-tRNA aminoacylation (GO:0006436) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of hh target transcription factor activity (GO:1990787) 1 0 .10 - < 0.01 1.00E00 1.00E00 threonyl-tRNA aminoacylation (GO:0006435) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to dsDNA (GO:1990786) 2 0 .20 - < 0.01 1.00E00 1.00E00 seryl-tRNA aminoacylation (GO:0006434) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of timing of anagen (GO:0051885) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to water-immersion restraint stress (GO:1990785) 1 0 .10 - < 0.01 1.00E00 1.00E00 prolyl-tRNA aminoacylation (GO:0006433) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of timing of anagen (GO:0051884) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to dsDNA (GO:1990784) 2 0 .20 - < 0.01 1.00E00 1.00E00 phenylalanyl-tRNA aminoacylation (GO:0006432) 3 0 .30 - < 0.01 1.00E00 1.00E00 methionyl-tRNA aminoacylation (GO:0006431) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of Schwann cell differentiation (GO:0014040) 4 0 .40 - < 0.01 1.00E00 1.00E00 lysyl-tRNA aminoacylation (GO:0006430) 1 0 .10 - < 0.01 1.00E00 1.00E00 acrosome matrix dispersal (GO:0002077) 1 0 .10 - < 0.01 1.00E00 1.00E00 extraocular skeletal muscle development (GO:0002074) 2 0 .20 - < 0.01 1.00E00 1.00E00 optic cup morphogenesis involved in camera-type eye development (GO:0002072) 6 0 .59 - < 0.01 1.00E00 1.00E00 glandular epithelial cell maturation (GO:0002071) 2 0 .20 - < 0.01 1.00E00 1.00E00 leucyl-tRNA aminoacylation (GO:0006429) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of Schwann cell differentiation (GO:0014038) 4 0 .40 - < 0.01 1.00E00 1.00E00 isoleucyl-tRNA aminoacylation (GO:0006428) 2 0 .20 - < 0.01 1.00E00 1.00E00 histidyl-tRNA aminoacylation (GO:0006427) 2 0 .20 - < 0.01 1.00E00 1.00E00 lateral element assembly (GO:0051878) 1 0 .10 - < 0.01 1.00E00 1.00E00 glycyl-tRNA aminoacylation (GO:0006426) 1 0 .10 - < 0.01 1.00E00 1.00E00 glutaminyl-tRNA aminoacylation (GO:0006425) 1 0 .10 - < 0.01 1.00E00 1.00E00 neural crest cell fate commitment (GO:0014034) 1 0 .10 - < 0.01 1.00E00 1.00E00 glutamyl-tRNA aminoacylation (GO:0006424) 2 0 .20 - < 0.01 1.00E00 1.00E00 cysteinyl-tRNA aminoacylation (GO:0006423) 2 0 .20 - < 0.01 1.00E00 1.00E00 aspartyl-tRNA aminoacylation (GO:0006422) 1 0 .10 - < 0.01 1.00E00 1.00E00 asparaginyl-tRNA aminoacylation (GO:0006421) 3 0 .30 - < 0.01 1.00E00 1.00E00 arginyl-tRNA aminoacylation (GO:0006420) 3 0 .30 - < 0.01 1.00E00 1.00E00 clathrin-dependent extracellular exosome endocytosis (GO:1990771) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to pheromone (GO:0071444) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of histone H3-K14 acetylation (GO:0071442) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of histone H3-K14 acetylation (GO:0071441) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of histone H3-K14 acetylation (GO:0071440) 7 0 .69 - < 0.01 1.00E00 1.00E00 alanyl-tRNA aminoacylation (GO:0006419) 2 0 .20 - < 0.01 1.00E00 1.00E00 notochord formation (GO:0014028) 3 0 .30 - < 0.01 1.00E00 1.00E00 prostaglandin receptor internalization (GO:1990767) 1 0 .10 - < 0.01 1.00E00 1.00E00 general adaptation syndrome (GO:0051866) 1 0 .10 - < 0.01 1.00E00 1.00E00 translational initiation (GO:0006413) 49 0 4.84 - < 0.01 2.05E-02 3.51E-01 neural plate elongation (GO:0014022) 3 0 .30 - < 0.01 1.00E00 1.00E00 maintenance of epithelial cell apical/basal polarity (GO:0045199) 7 0 .69 - < 0.01 1.00E00 1.00E00 establishment of epithelial cell apical/basal polarity (GO:0045198) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197) 36 0 3.56 - < 0.01 7.23E-02 7.40E-01 establishment or maintenance of neuroblast polarity (GO:0045196) 3 0 .30 - < 0.01 1.00E00 1.00E00 isotype switching (GO:0045190) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 tRNA-containing ribonucleoprotein complex export from nucleus (GO:0071431) 3 0 .30 - < 0.01 1.00E00 1.00E00 tRNA export from nucleus (GO:0006409) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of proteasomal protein catabolic process (GO:1901799) 47 0 4.65 - < 0.01 1.98E-02 3.42E-01 snRNA export from nucleus (GO:0006408) 1 0 .10 - < 0.01 1.00E00 1.00E00 rRNA export from nucleus (GO:0006407) 2 0 .20 - < 0.01 1.00E00 1.00E00 neuroblast differentiation (GO:0014016) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitotic sister chromatid biorientation (GO:1990758) 1 0 .10 - < 0.01 1.00E00 1.00E00 mRNA export from nucleus (GO:0006406) 44 0 4.35 - < 0.01 3.06E-02 4.54E-01 RNA export from nucleus (GO:0006405) 55 0 5.44 - < 0.01 8.62E-03 1.94E-01 RNA import into nucleus (GO:0006404) 3 0 .30 - < 0.01 1.00E00 1.00E00 mitotic spindle microtubule depolymerization (GO:1990755) 1 0 .10 - < 0.01 1.00E00 1.00E00 peripheral nervous system axon regeneration (GO:0014012) 2 0 .20 - < 0.01 1.00E00 1.00E00 Schwann cell proliferation (GO:0014010) 2 0 .20 - < 0.01 1.00E00 1.00E00 blood vessel endothelial cell migration involved in intussusceptive angiogenesis (GO:0002044) 1 0 .10 - < 0.01 1.00E00 1.00E00 blood vessel endothelial cell proliferation involved in sprouting angiogenesis (GO:0002043) 5 0 .49 - < 0.01 1.00E00 1.00E00 intussusceptive angiogenesis (GO:0002041) 1 0 .10 - < 0.01 1.00E00 1.00E00 zonula adherens assembly (GO:0045186) 2 0 .20 - < 0.01 1.00E00 1.00E00 rRNA-containing ribonucleoprotein complex export from nucleus (GO:0071428) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 mRNA-containing ribonucleoprotein complex export from nucleus (GO:0071427) 44 0 4.35 - < 0.01 3.06E-02 4.54E-01 ribonucleoprotein complex export from nucleus (GO:0071426) 60 0 5.93 - < 0.01 5.70E-03 1.40E-01 malate transmembrane transport (GO:0071423) 4 0 .40 - < 0.01 1.00E00 1.00E00 succinate transmembrane transport (GO:0071422) 6 0 .59 - < 0.01 1.00E00 1.00E00 cellular response to histamine (GO:0071420) 5 0 .49 - < 0.01 1.00E00 1.00E00 benzoyl-CoA metabolic process (GO:1901787) 1 0 .10 - < 0.01 1.00E00 1.00E00 primary miRNA methylation (GO:1990744) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein sialylation (GO:1990743) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of L-glutamate import across plasma membrane (GO:0002038) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of L-glutamate import across plasma membrane (GO:0002037) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of L-glutamate import across plasma membrane (GO:0002036) 7 0 .69 - < 0.01 1.00E00 1.00E00 maintenance of blood vessel diameter homeostasis by renin-angiotensin (GO:0002034) 4 0 .40 - < 0.01 1.00E00 1.00E00 angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure (GO:0002033) 1 0 .10 - < 0.01 1.00E00 1.00E00 G protein-coupled receptor internalization (GO:0002031) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 apical protein localization (GO:0045176) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 basal protein localization (GO:0045175) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to amine stimulus (GO:0071418) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of synapse structural plasticity (GO:0051835) 3 0 .30 - < 0.01 1.00E00 1.00E00 UV-damage excision repair, DNA incision (GO:1990731) 1 0 .10 - < 0.01 1.00E00 1.00E00 reduction of food intake in response to dietary excess (GO:0002023) 3 0 .30 - < 0.01 1.00E00 1.00E00 clustering of voltage-gated potassium channels (GO:0045163) 2 0 .20 - < 0.01 1.00E00 1.00E00 clustering of voltage-gated sodium channels (GO:0045162) 5 0 .49 - < 0.01 1.00E00 1.00E00 neuronal ion channel clustering (GO:0045161) 9 0 .89 - < 0.01 1.00E00 1.00E00 cellular response to high density lipoprotein particle stimulus (GO:0071403) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to vitamin E (GO:0033197) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to triglyceride (GO:0071401) 1 0 .10 - < 0.01 1.00E00 1.00E00 primary miRNA modification (GO:1990729) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of blood volume by renal aldosterone (GO:0002017) 1 0 .10 - < 0.01 1.00E00 1.00E00 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure (GO:0002014) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to vitamin A (GO:0033189) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of histone ubiquitination (GO:0033184) 6 0 .59 - < 0.01 1.00E00 1.00E00 leukotriene A4 biosynthetic process (GO:1901753) 1 0 .10 - < 0.01 1.00E00 1.00E00 leukotriene A4 metabolic process (GO:1901751) 1 0 .10 - < 0.01 1.00E00 1.00E00 xylulose metabolic process (GO:0005997) 3 0 .30 - < 0.01 1.00E00 1.00E00 detection of hypoxic conditions in blood by chemoreceptor signaling (GO:0002007) 1 0 .10 - < 0.01 1.00E00 1.00E00 angiotensin maturation (GO:0002003) 1 0 .10 - < 0.01 1.00E00 1.00E00 trehalose metabolic process (GO:0005991) 1 0 .10 - < 0.01 1.00E00 1.00E00 male anatomical structure morphogenesis (GO:0090598) 4 0 .40 - < 0.01 1.00E00 1.00E00 meiotic telomere clustering (GO:0045141) 8 0 .79 - < 0.01 1.00E00 1.00E00 presynaptic active zone organization (GO:1990709) 5 0 .49 - < 0.01 1.00E00 1.00E00 calcineurin-NFAT signaling cascade (GO:0033173) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 conditioned place preference (GO:1990708) 3 0 .30 - < 0.01 1.00E00 1.00E00 cholangiocyte proliferation (GO:1990705) 2 0 .20 - < 0.01 1.00E00 1.00E00 lactose biosynthetic process (GO:0005989) 1 0 .10 - < 0.01 1.00E00 1.00E00 lactose metabolic process (GO:0005988) 1 0 .10 - < 0.01 1.00E00 1.00E00 nucleolar chromatin organization (GO:1990700) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of glycogen catabolic process (GO:0005981) 7 0 .69 - < 0.01 1.00E00 1.00E00 glycogen catabolic process (GO:0005980) 9 0 .89 - < 0.01 1.00E00 1.00E00 conversion of ds siRNA to ss siRNA involved in RNA interference (GO:0033168) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of vitamin A metabolic process (GO:1901738) 1 0 .10 - < 0.01 1.00E00 1.00E00 immunoglobulin V(D)J recombination (GO:0033152) 8 0 .79 - < 0.01 1.00E00 1.00E00 detection of oxidative stress (GO:0070994) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of histone deacetylase activity (GO:1901726) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of cell proliferation involved in kidney development (GO:1901723) 5 0 .49 - < 0.01 1.00E00 1.00E00 intermediate filament bundle assembly (GO:0045110) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of intracellular estrogen receptor signaling pathway (GO:0033148) 10 0 .99 - < 0.01 1.00E00 1.00E00 negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 oxidative demethylation (GO:0070989) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 regulation of intracellular estrogen receptor signaling pathway (GO:0033146) 32 0 3.16 - < 0.01 1.12E-01 9.21E-01 positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 error-free translesion synthesis (GO:0070987) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) 6 0 .59 - < 0.01 1.00E00 1.00E00 L-asparagine metabolic process (GO:0070982) 1 0 .10 - < 0.01 1.00E00 1.00E00 biphenyl catabolic process (GO:0070980) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of intermediate filament polymerization or depolymerization (GO:0045108) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of glucokinase activity (GO:0033132) 2 0 .20 - < 0.01 1.00E00 1.00E00 mesenchymal cell differentiation involved in bone development (GO:1901706) 1 0 .10 - < 0.01 1.00E00 1.00E00 detection of chemical stimulus involved in sensory perception of sweet taste (GO:0001582) 1 0 .10 - < 0.01 1.00E00 1.00E00 detection of chemical stimulus involved in sensory perception of sour taste (GO:0001581) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of histone phosphorylation (GO:0033129) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of histone phosphorylation (GO:0033128) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of histone phosphorylation (GO:0033127) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 positive regulation of neutrophil mediated killing of fungus (GO:0070965) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of neutrophil mediated killing of gram-negative bacterium (GO:0070963) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of neutrophil mediated killing of bacterium (GO:0070962) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of neutrophil mediated killing of symbiont cell (GO:0070961) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of neutrophil mediated cytotoxicity (GO:0070960) 4 0 .40 - < 0.01 1.00E00 1.00E00 medium-chain fatty acid transport (GO:0001579) 2 0 .20 - < 0.01 1.00E00 1.00E00 globoside biosynthetic process (GO:0001576) 2 0 .20 - < 0.01 1.00E00 1.00E00 globoside metabolic process (GO:0001575) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of RNA splicing (GO:0033119) 28 0 2.77 - < 0.01 1.73E-01 9.70E-01 regulation of neutrophil mediated killing of fungus (GO:0070953) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of neutrophil mediated killing of gram-negative bacterium (GO:0070951) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of neutrophil mediated killing of bacterium (GO:0070950) 2 0 .20 - < 0.01 1.00E00 1.00E00 cell septum assembly (GO:0090529) 1 0 .10 - < 0.01 1.00E00 1.00E00 fatty acid alpha-oxidation (GO:0001561) 5 0 .49 - < 0.01 1.00E00 1.00E00 vesicle tethering involved in exocytosis (GO:0090522) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cell growth by extracellular stimulus (GO:0001560) 1 0 .10 - < 0.01 1.00E00 1.00E00 glomerular visceral epithelial cell migration (GO:0090521) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of neutrophil mediated killing of symbiont cell (GO:0070949) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of neutrophil mediated cytotoxicity (GO:0070948) 7 0 .69 - < 0.01 1.00E00 1.00E00 dephosphorylation of RNA polymerase II C-terminal domain (GO:0070940) 5 0 .49 - < 0.01 1.00E00 1.00E00 oocyte growth (GO:0001555) 2 0 .20 - < 0.01 1.00E00 1.00E00 cyclic-GMP-AMP transmembrane import across plasma membrane (GO:0140361) 3 0 .30 - < 0.01 1.00E00 1.00E00 ovarian follicle atresia (GO:0001552) 2 0 .20 - < 0.01 1.00E00 1.00E00 ovarian cumulus expansion (GO:0001550) 1 0 .10 - < 0.01 1.00E00 1.00E00 tooth eruption (GO:0044691) 5 0 .49 - < 0.01 1.00E00 1.00E00 CRD-mediated mRNA stabilization (GO:0070934) 4 0 .40 - < 0.01 1.00E00 1.00E00 histone H4 deacetylation (GO:0070933) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 histone H3 deacetylation (GO:0070932) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 positive regulation of ubiquitin-dependent endocytosis (GO:2000397) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of ubiquitin-dependent endocytosis (GO:2000395) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of lamellipodium morphogenesis (GO:2000394) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of lamellipodium morphogenesis (GO:2000393) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of lamellipodium morphogenesis (GO:2000392) 9 0 .89 - < 0.01 1.00E00 1.00E00 antral ovarian follicle growth (GO:0001547) 4 0 .40 - < 0.01 1.00E00 1.00E00 preantral ovarian follicle growth (GO:0001546) 1 0 .10 - < 0.01 1.00E00 1.00E00 primary ovarian follicle growth (GO:0001545) 1 0 .10 - < 0.01 1.00E00 1.00E00 initiation of primordial ovarian follicle growth (GO:0001544) 2 0 .20 - < 0.01 1.00E00 1.00E00 ovarian follicle rupture (GO:0001543) 2 0 .20 - < 0.01 1.00E00 1.00E00 ovulation from ovarian follicle (GO:0001542) 10 0 .99 - < 0.01 1.00E00 1.00E00 RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 regulation of ATP:ADP antiporter activity (GO:0070926) 1 0 .10 - < 0.01 1.00E00 1.00E00 small RNA loading onto RISC (GO:0070922) 9 0 .89 - < 0.01 1.00E00 1.00E00 positive regulation of antral ovarian follicle growth (GO:2000388) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of antral ovarian follicle growth (GO:2000387) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of ovarian follicle development (GO:2000386) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of ectoderm development (GO:2000384) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of ectoderm development (GO:2000383) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of mesoderm development (GO:2000382) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of mesoderm development (GO:2000381) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mesoderm development (GO:2000380) 3 0 .30 - < 0.01 1.00E00 1.00E00 UV-damage excision repair (GO:0070914) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 positive regulation of oxygen metabolic process (GO:2000376) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of oxygen metabolic process (GO:2000374) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity (GO:2000373) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of DNA topoisomerase (ATP-hydrolyzing) activity (GO:2000371) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of clathrin-dependent endocytosis (GO:2000370) 6 0 .59 - < 0.01 1.00E00 1.00E00 aminophospholipid translocation (GO:0140331) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial tRNA pseudouridine synthesis (GO:0070902) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial tRNA methylation (GO:0070901) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitochondrial tRNA modification (GO:0070900) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of acrosomal vesicle exocytosis (GO:2000368) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of acrosomal vesicle exocytosis (GO:2000367) 2 0 .20 - < 0.01 1.00E00 1.00E00 lysophospholipid translocation (GO:0140329) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptide amidation (GO:0001519) 1 0 .10 - < 0.01 1.00E00 1.00E00 selenocysteine incorporation (GO:0001514) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation by symbiont of host autophagy (GO:0140321) 1 0 .10 - < 0.01 1.00E00 1.00E00 RNA methylation (GO:0001510) 69 0 6.82 - < 0.01 2.50E-03 7.47E-02 negative regulation of interferon-alpha production (GO:0032687) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of granulocyte macrophage colony-stimulating factor production (GO:0032685) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of connective tissue growth factor production (GO:0032683) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of lymphotoxin A production (GO:0032681) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of ovarian follicle development (GO:2000355) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of CD40 signaling pathway (GO:2000350) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone H3-K4 dimethylation (GO:0044648) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of TRAIL production (GO:0032679) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of CD40 signaling pathway (GO:2000349) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of interleukin-3 production (GO:0032672) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of CD40 signaling pathway (GO:2000348) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of acrosome reaction (GO:2000344) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of chemokine (C-X-C motif) ligand 1 production (GO:2000340) 4 0 .40 - < 0.01 1.00E00 1.00E00 serine import into mitochondrion (GO:0140300) 3 0 .30 - < 0.01 1.00E00 1.00E00 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine (GO:0018395) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of viral release from host cell (GO:1902187) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 regulation of interleukin-21 production (GO:0032665) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of chemokine (C-X-C motif) ligand 1 production (GO:2000338) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of terminal button organization (GO:2000331) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of T-helper 17 cell lineage commitment (GO:2000330) 1 0 .10 - < 0.01 1.00E00 1.00E00 fibroblast growth factor receptor apoptotic signaling pathway (GO:1902178) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (GO:1902177) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of keratinocyte apoptotic process (GO:1902173) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of interleukin-15 production (GO:0032658) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of T-helper 17 cell lineage commitment (GO:2000329) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of T-helper 17 cell lineage commitment (GO:2000328) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of glucocorticoid receptor signaling pathway (GO:2000324) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of glucocorticoid receptor signaling pathway (GO:2000323) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of glucocorticoid receptor signaling pathway (GO:2000322) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of T-helper 17 cell differentiation (GO:2000320) 10 0 .99 - < 0.01 1.00E00 1.00E00 protein myristoylation (GO:0018377) 4 0 .40 - < 0.01 1.00E00 1.00E00 metabolism of macromolecule in other organism involved in symbiotic interaction (GO:0052229) 2 0 .20 - < 0.01 1.00E00 1.00E00 catabolism of substance in other organism involved in symbiotic interaction (GO:0052227) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator (GO:1902164) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator (GO:1902163) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator (GO:1902162) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of cyclic nucleotide-gated ion channel activity (GO:1902161) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of fractalkine production (GO:0032644) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of connective tissue growth factor production (GO:0032643) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of T-helper 17 type immune response (GO:2000317) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 tumor necrosis factor production (GO:0032640) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation (GO:2000314) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation (GO:2000313) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of kainate selective glutamate receptor activity (GO:2000312) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of cyclic nucleotide-gated ion channel activity (GO:1902159) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-glutamine methylation (GO:0018364) 6 0 .59 - < 0.01 1.00E00 1.00E00 metabolism of substance in other organism involved in symbiotic interaction (GO:0052214) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of response to DNA damage checkpoint signaling (GO:1902153) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of response to DNA integrity checkpoint signaling (GO:1902151) 1 0 .10 - < 0.01 1.00E00 1.00E00 mRNA 3'-end processing by stem-loop binding and cleavage (GO:0006398) 5 0 .49 - < 0.01 1.00E00 1.00E00 interleukin-9 production (GO:0032638) 1 0 .10 - < 0.01 1.00E00 1.00E00 termination of mitochondrial transcription (GO:0006393) 3 0 .30 - < 0.01 1.00E00 1.00E00 transcription initiation from mitochondrial promoter (GO:0006391) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of synaptic vesicle exocytosis (GO:2000301) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of response to cell cycle checkpoint signaling (GO:1902145) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein-pyridoxal-5-phosphate linkage (GO:0018352) 1 0 .10 - < 0.01 1.00E00 1.00E00 modulation of molecular function in other organism involved in symbiotic interaction (GO:0052205) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of molecular function in other organism involved in symbiotic interaction (GO:0052204) 3 0 .30 - < 0.01 1.00E00 1.00E00 modulation of catalytic activity in other organism involved in symbiotic interaction (GO:0052203) 2 0 .20 - < 0.01 1.00E00 1.00E00 tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) 9 0 .89 - < 0.01 1.00E00 1.00E00 response to host defenses (GO:0052200) 1 0 .10 - < 0.01 1.00E00 1.00E00 termination of RNA polymerase III transcription (GO:0006386) 1 0 .10 - < 0.01 1.00E00 1.00E00 transcription initiation from RNA polymerase III promoter (GO:0006384) 6 0 .59 - < 0.01 1.00E00 1.00E00 transcription by RNA polymerase III (GO:0006383) 23 0 2.27 - < 0.01 2.61E-01 1.00E00 adenosine to inosine editing (GO:0006382) 6 0 .59 - < 0.01 1.00E00 1.00E00 interleukin-21 production (GO:0032625) 1 0 .10 - < 0.01 1.00E00 1.00E00 interleukin-18 production (GO:0032621) 2 0 .20 - < 0.01 1.00E00 1.00E00 interleukin-17 production (GO:0032620) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein geranylgeranylation (GO:0018344) 6 0 .59 - < 0.01 1.00E00 1.00E00 protein farnesylation (GO:0018343) 4 0 .40 - < 0.01 1.00E00 1.00E00 protein prenylation (GO:0018342) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 interleukin-15 production (GO:0032618) 1 0 .10 - < 0.01 1.00E00 1.00E00 interleukin-12 production (GO:0032615) 2 0 .20 - < 0.01 1.00E00 1.00E00 7-methylguanosine mRNA capping (GO:0006370) 7 0 .69 - < 0.01 1.00E00 1.00E00 interleukin-10 production (GO:0032613) 2 0 .20 - < 0.01 1.00E00 1.00E00 interleukin-1 alpha production (GO:0032610) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein succinylation (GO:0018335) 4 0 .40 - < 0.01 1.00E00 1.00E00 cellular response to progesterone stimulus (GO:0071393) 3 0 .30 - < 0.01 1.00E00 1.00E00 termination of RNA polymerase II transcription (GO:0006369) 6 0 .59 - < 0.01 1.00E00 1.00E00 transcription elongation from RNA polymerase II promoter (GO:0006368) 23 0 2.27 - < 0.01 2.61E-01 1.00E00 transcription initiation from RNA polymerase II promoter (GO:0006367) 30 0 2.97 - < 0.01 1.07E-01 9.00E-01 termination of RNA polymerase I transcription (GO:0006363) 3 0 .30 - < 0.01 1.00E00 1.00E00 interferon-alpha production (GO:0032607) 4 0 .40 - < 0.01 1.00E00 1.00E00 transcription elongation from RNA polymerase I promoter (GO:0006362) 6 0 .59 - < 0.01 1.00E00 1.00E00 type I interferon production (GO:0032606) 9 0 .89 - < 0.01 1.00E00 1.00E00 transcription initiation from RNA polymerase I promoter (GO:0006361) 8 0 .79 - < 0.01 1.00E00 1.00E00 transcription by RNA polymerase I (GO:0006360) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 granulocyte macrophage colony-stimulating factor production (GO:0032604) 1 0 .10 - < 0.01 1.00E00 1.00E00 chemokine receptor transport out of membrane raft (GO:0032600) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to cortisol stimulus (GO:0071387) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to corticosterone stimulus (GO:0071386) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein tyrosinylation (GO:0018322) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to prostaglandin E stimulus (GO:0071380) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 regulation of transcription by RNA polymerase III (GO:0006359) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 regulation of transcription by RNA polymerase I (GO:0006356) 33 0 3.26 - < 0.01 6.95E-02 7.23E-01 DNA-templated transcription, initiation (GO:0006352) 54 0 5.34 - < 0.01 1.38E-02 2.69E-01 intracellular transport of virus (GO:0075733) 2 0 .20 - < 0.01 1.00E00 1.00E00 viral penetration into host nucleus (GO:0075732) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to prostaglandin stimulus (GO:0071379) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 cellular response to growth hormone stimulus (GO:0071378) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 protein C-linked glycosylation via tryptophan (GO:0018317) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902109) 4 0 .40 - < 0.01 1.00E00 1.00E00 molybdenum incorporation into molybdenum-molybdopterin complex (GO:0018315) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to parathyroid hormone stimulus (GO:0071374) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular response to luteinizing hormone stimulus (GO:0071373) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-serine ADP-ribosylation (GO:0018312) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of metaphase/anaphase transition of meiotic cell cycle (GO:1902103) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of metaphase/anaphase transition of meiotic cell cycle (GO:1902102) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of gene expression by genetic imprinting (GO:0006349) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 DNA methylation-dependent heterochromatin assembly (GO:0006346) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of timing of catagen (GO:0051795) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of timing of catagen (GO:0051794) 1 0 .10 - < 0.01 1.00E00 1.00E00 medium-chain fatty acid catabolic process (GO:0051793) 4 0 .40 - < 0.01 1.00E00 1.00E00 medium-chain fatty acid biosynthetic process (GO:0051792) 5 0 .49 - < 0.01 1.00E00 1.00E00 medium-chain fatty acid metabolic process (GO:0051791) 10 0 .99 - < 0.01 1.00E00 1.00E00 short-chain fatty acid biosynthetic process (GO:0051790) 4 0 .40 - < 0.01 1.00E00 1.00E00 cellular response to ether (GO:0071362) 8 0 .79 - < 0.01 1.00E00 1.00E00 nucleosome disassembly (GO:0006337) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 DNA replication-independent nucleosome assembly (GO:0006336) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 DNA replication-dependent nucleosome assembly (GO:0006335) 9 0 .89 - < 0.01 1.00E00 1.00E00 DNA double-strand break attachment to nuclear envelope (GO:1990683) 2 0 .20 - < 0.01 1.00E00 1.00E00 behavioral response to nutrient (GO:0051780) 1 0 .10 - < 0.01 1.00E00 1.00E00 establishment of integrated proviral latency (GO:0075713) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-2 (GO:0071352) 2 0 .20 - < 0.01 1.00E00 1.00E00 histone H4-K12 deacetylation (GO:1990679) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone H4-K16 deacetylation (GO:1990678) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to redox state (GO:0051775) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of nitric-oxide synthase biosynthetic process (GO:0051771) 6 0 .59 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-11 (GO:0071348) 1 0 .10 - < 0.01 1.00E00 1.00E00 meiotic gene conversion (GO:0006311) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of hair follicle cell proliferation (GO:0071338) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091) 9 0 .89 - < 0.01 1.00E00 1.00E00 hair follicle cell proliferation (GO:0071335) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to fructose stimulus (GO:0071332) 2 0 .20 - < 0.01 1.00E00 1.00E00 apoptotic DNA fragmentation (GO:0006309) 8 0 .79 - < 0.01 1.00E00 1.00E00 DNA dealkylation involved in DNA repair (GO:0006307) 6 0 .59 - < 0.01 1.00E00 1.00E00 homologous chromosome movement towards spindle pole in meiosis I anaphase (GO:0051758) 1 0 .10 - < 0.01 1.00E00 1.00E00 cannabinoid biosynthetic process (GO:1901696) 1 0 .10 - < 0.01 1.00E00 1.00E00 meiotic sister chromatid cohesion, centromeric (GO:0051754) 4 0 .40 - < 0.01 1.00E00 1.00E00 sebum secreting cell proliferation (GO:1990654) 1 0 .10 - < 0.01 1.00E00 1.00E00 postreplication repair (GO:0006301) 25 0 2.47 - < 0.01 1.63E-01 1.00E00 cellular response to cGMP (GO:0071321) 4 0 .40 - < 0.01 1.00E00 1.00E00 glutathione derivative biosynthetic process (GO:1901687) 1 0 .10 - < 0.01 1.00E00 1.00E00 glutathione derivative metabolic process (GO:1901685) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to ATP (GO:0071318) 10 0 .99 - < 0.01 1.00E00 1.00E00 cellular response to isoquinoline alkaloid (GO:0071317) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to nicotine (GO:0071316) 5 0 .49 - < 0.01 1.00E00 1.00E00 cellular response to morphine (GO:0071315) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of histone H3-K27 acetylation (GO:1901676) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of histone H3-K27 acetylation (GO:1901675) 1 0 .10 - < 0.01 1.00E00 1.00E00 reproductive senescence (GO:1990636) 1 0 .10 - < 0.01 1.00E00 1.00E00 cytotoxic T cell differentiation (GO:0045065) 1 0 .10 - < 0.01 1.00E00 1.00E00 T-helper 2 cell differentiation (GO:0045064) 4 0 .40 - < 0.01 1.00E00 1.00E00 extrathymic T cell selection (GO:0045062) 2 0 .20 - < 0.01 1.00E00 1.00E00 germline cell cycle switching, mitotic to meiotic cell cycle (GO:0051729) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell cycle switching, mitotic to meiotic cell cycle (GO:0051728) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein de-ADP-ribosylation (GO:0051725) 5 0 .49 - < 0.01 1.00E00 1.00E00 quinone catabolic process (GO:1901662) 2 0 .20 - < 0.01 1.00E00 1.00E00 constitutive secretory pathway (GO:0045054) 4 0 .40 - < 0.01 1.00E00 1.00E00 protein insertion into ER membrane by stop-transfer membrane-anchor sequence (GO:0045050) 10 0 .99 - < 0.01 1.00E00 1.00E00 glycosyl compound biosynthetic process (GO:1901659) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 regulation of extrathymic T cell differentiation (GO:0033082) 2 0 .20 - < 0.01 1.00E00 1.00E00 immature T cell proliferation in thymus (GO:0033080) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial membrane fusion (GO:1990613) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein insertion into ER membrane (GO:0045048) 19 0 1.88 - < 0.01 4.08E-01 1.00E00 protein import into peroxisome membrane (GO:0045046) 6 0 .59 - < 0.01 1.00E00 1.00E00 mesenchymal cell migration (GO:0090497) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein import into mitochondrial intermembrane space (GO:0045041) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein insertion into mitochondrial outer membrane (GO:0045040) 4 0 .40 - < 0.01 1.00E00 1.00E00 immature T cell proliferation (GO:0033079) 1 0 .10 - < 0.01 1.00E00 1.00E00 extrathymic T cell differentiation (GO:0033078) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of synoviocyte proliferation (GO:1901647) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of synoviocyte proliferation (GO:1901645) 2 0 .20 - < 0.01 1.00E00 1.00E00 pyrimidine nucleotide-sugar transmembrane transport (GO:0090481) 9 0 .89 - < 0.01 1.00E00 1.00E00 purine nucleotide-sugar transmembrane transport (GO:0090480) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic vesicle membrane organization (GO:1901634) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of synaptic vesicle membrane organization (GO:1901632) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of presynaptic membrane organization (GO:1901631) 2 0 .20 - < 0.01 1.00E00 1.00E00 dibasic protein processing (GO:0090472) 1 0 .10 - < 0.01 1.00E00 1.00E00 directional locomotion (GO:0033058) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitochondrial tRNA wobble uridine modification (GO:0070899) 1 0 .10 - < 0.01 1.00E00 1.00E00 RNA polymerase III preinitiation complex assembly (GO:0070898) 1 0 .10 - < 0.01 1.00E00 1.00E00 transcription preinitiation complex assembly (GO:0070897) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 regulation of presynaptic membrane organization (GO:1901629) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of postsynaptic membrane organization (GO:1901628) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of transposon integration (GO:0070895) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of postsynaptic membrane organization (GO:1901627) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of transposon integration (GO:0070894) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of postsynaptic membrane organization (GO:1901626) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of lymphocyte chemotaxis (GO:1901624) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning (GO:1901622) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial magnesium ion transmembrane transport (GO:0045016) 1 0 .10 - < 0.01 1.00E00 1.00E00 glutamate homeostasis (GO:0090461) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of proline transport (GO:0070881) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of vesicle transport along microtubule (GO:1901610) 5 0 .49 - < 0.01 1.00E00 1.00E00 DNA deamination (GO:0045006) 6 0 .59 - < 0.01 1.00E00 1.00E00 DNA replication proofreading (GO:0045004) 2 0 .20 - < 0.01 1.00E00 1.00E00 double-strand break repair via single-strand annealing (GO:0045002) 5 0 .49 - < 0.01 1.00E00 1.00E00 polysaccharide localization (GO:0033037) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of vesicle transport along microtubule (GO:1901609) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of vesicle transport along microtubule (GO:1901608) 6 0 .59 - < 0.01 1.00E00 1.00E00 alpha-amino acid biosynthetic process (GO:1901607) 45 0 4.45 - < 0.01 3.15E-02 4.59E-01 endocytic iron import into cell (GO:0140298) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-glutamate ADP-deribosylation (GO:0140291) 3 0 .30 - < 0.01 1.00E00 1.00E00 heterochromatin organization involved in chromatin silencing (GO:0070868) 7 0 .69 - < 0.01 1.00E00 1.00E00 mast cell homeostasis (GO:0033023) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to nuclear envelope (GO:0090435) 10 0 .99 - < 0.01 1.00E00 1.00E00 negative regulation of bile acid biosynthetic process (GO:0070858) 2 0 .20 - < 0.01 1.00E00 1.00E00 acinar cell differentiation (GO:0090425) 1 0 .10 - < 0.01 1.00E00 1.00E00 hexose import across plasma membrane (GO:0140271) 4 0 .40 - < 0.01 1.00E00 1.00E00 Hsp90 deacetylation (GO:0070846) 1 0 .10 - < 0.01 1.00E00 1.00E00 polyubiquitinated misfolded protein transport (GO:0070845) 1 0 .10 - < 0.01 1.00E00 1.00E00 polyubiquitinated protein transport (GO:0070844) 1 0 .10 - < 0.01 1.00E00 1.00E00 misfolded protein transport (GO:0070843) 1 0 .10 - < 0.01 1.00E00 1.00E00 doxorubicin metabolic process (GO:0044598) 5 0 .49 - < 0.01 1.00E00 1.00E00 daunorubicin metabolic process (GO:0044597) 5 0 .49 - < 0.01 1.00E00 1.00E00 malonate catabolic process (GO:0090410) 1 0 .10 - < 0.01 1.00E00 1.00E00 caveola assembly (GO:0070836) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of Rho-dependent protein serine/threonine kinase activity (GO:2000299) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of Rho-dependent protein serine/threonine kinase activity (GO:2000298) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of synapse maturation (GO:2000297) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of defecation (GO:2000293) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of defecation (GO:2000292) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of catalytic activity in other organism involved in symbiotic interaction (GO:0052199) 1 0 .10 - < 0.01 1.00E00 1.00E00 oxidative stress-induced premature senescence (GO:0090403) 3 0 .30 - < 0.01 1.00E00 1.00E00 stress-induced premature senescence (GO:0090400) 6 0 .59 - < 0.01 1.00E00 1.00E00 heterochromatin maintenance (GO:0070829) 6 0 .59 - < 0.01 1.00E00 1.00E00 chromatin maintenance (GO:0070827) 8 0 .79 - < 0.01 1.00E00 1.00E00 butyryl-CoA catabolic process (GO:0044580) 1 0 .10 - < 0.01 1.00E00 1.00E00 receptor internalization involved in canonical Wnt signaling pathway (GO:2000286) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of cellular amino acid biosynthetic process (GO:2000284) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein catabolic process at synapse (GO:0140246) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cellular amino acid biosynthetic process (GO:2000282) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of translation at postsynapse (GO:0140245) 4 0 .40 - < 0.01 1.00E00 1.00E00 peripheral nervous system neuron axonogenesis (GO:0048936) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of translation at presynapse (GO:0140244) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of translation at synapse (GO:0140243) 7 0 .69 - < 0.01 1.00E00 1.00E00 modification of cellular component in other organism involved in symbiotic interaction (GO:0052188) 1 0 .10 - < 0.01 1.00E00 1.00E00 modification by host of symbiont cellular component (GO:0052187) 1 0 .10 - < 0.01 1.00E00 1.00E00 modification of structure of other organism involved in symbiotic interaction (GO:0052185) 1 0 .10 - < 0.01 1.00E00 1.00E00 modification by host of symbiont structure (GO:0052183) 1 0 .10 - < 0.01 1.00E00 1.00E00 phosphorylation of RNA polymerase II C-terminal domain (GO:0070816) 9 0 .89 - < 0.01 1.00E00 1.00E00 [2Fe-2S] cluster assembly (GO:0044571) 4 0 .40 - < 0.01 1.00E00 1.00E00 hydrogen sulfide biosynthetic process (GO:0070814) 3 0 .30 - < 0.01 1.00E00 1.00E00 hydrogen sulfide metabolic process (GO:0070813) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of oxidative phosphorylation uncoupler activity (GO:2000277) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of oxidative phosphorylation uncoupler activity (GO:2000276) 1 0 .10 - < 0.01 1.00E00 1.00E00 postsynaptic endocytosis (GO:0140239) 10 0 .99 - < 0.01 1.00E00 1.00E00 regulation of oxidative phosphorylation uncoupler activity (GO:2000275) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of fibroblast apoptotic process (GO:2000271) 6 0 .59 - < 0.01 1.00E00 1.00E00 lateral line system development (GO:0048925) 1 0 .10 - < 0.01 1.00E00 1.00E00 posterior lateral line neuromast hair cell differentiation (GO:0048923) 1 0 .10 - < 0.01 1.00E00 1.00E00 dendritic cell proliferation (GO:0044565) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to defenses of other organism (GO:0052173) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein transport out of membrane raft (GO:0032599) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein transport into membrane raft (GO:0032596) 4 0 .40 - < 0.01 1.00E00 1.00E00 protein transport within lipid bilayer (GO:0032594) 9 0 .89 - < 0.01 1.00E00 1.00E00 regulation of blood coagulation, intrinsic pathway (GO:2000266) 1 0 .10 - < 0.01 1.00E00 1.00E00 posterior lateral line neuromast development (GO:0048919) 1 0 .10 - < 0.01 1.00E00 1.00E00 posterior lateral line development (GO:0048916) 1 0 .10 - < 0.01 1.00E00 1.00E00 posterior lateral line system development (GO:0048915) 1 0 .10 - < 0.01 1.00E00 1.00E00 ER-dependent peroxisome organization (GO:0032581) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein activation cascade (GO:2000257) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of feeding behavior (GO:2000253) 7 0 .69 - < 0.01 1.00E00 1.00E00 guanine nucleotide transport (GO:0001408) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of long-chain fatty acid import into cell (GO:0140214) 3 0 .30 - < 0.01 1.00E00 1.00E00 NLRP3 inflammasome complex assembly (GO:0044546) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation by symbiont of host apoptotic process (GO:0052151) 3 0 .30 - < 0.01 1.00E00 1.00E00 tRNA surveillance (GO:0106354) 6 0 .59 - < 0.01 1.00E00 1.00E00 protein-chromophore linkage (GO:0018298) 4 0 .40 - < 0.01 1.00E00 1.00E00 protein-FAD linkage (GO:0018293) 1 0 .10 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor localization to postsynaptic specialization membrane (GO:0099645) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 negative regulation of peptidyl-cysteine S-nitrosylation (GO:1902083) 6 0 .59 - < 0.01 1.00E00 1.00E00 retrograde axonal protein transport (GO:0099642) 2 0 .20 - < 0.01 1.00E00 1.00E00 anterograde axonal protein transport (GO:0099641) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of calcium ion import into sarcoplasmic reticulum (GO:1902081) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of calcium ion import into sarcoplasmic reticulum (GO:1902080) 2 0 .20 - < 0.01 1.00E00 1.00E00 snRNA methylation (GO:0106349) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of rRNA processing (GO:2000234) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of rRNA processing (GO:2000233) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of rRNA processing (GO:2000232) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 omega-hydroxyceramide biosynthetic process (GO:0106342) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of pancreatic stellate cell proliferation (GO:2000231) 1 0 .10 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor transport, endosome to plasma membrane (GO:0099639) 8 0 .79 - < 0.01 1.00E00 1.00E00 endosome to plasma membrane protein transport (GO:0099638) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 neurotransmitter receptor transport (GO:0099637) 20 0 1.98 - < 0.01 2.51E-01 1.00E00 regulation of mitochondrial mRNA stability (GO:0044528) 7 0 .69 - < 0.01 1.00E00 1.00E00 iron incorporation into metallo-sulfur cluster (GO:0018283) 2 0 .20 - < 0.01 1.00E00 1.00E00 metal incorporation into metallo-sulfur cluster (GO:0018282) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein localization to postsynaptic specialization membrane (GO:0099633) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 positive regulation of hypoxia-inducible factor-1alpha signaling pathway (GO:1902073) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein sulfhydration (GO:0044524) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of hypoxia-inducible factor-1alpha signaling pathway (GO:1902072) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of hypoxia-inducible factor-1alpha signaling pathway (GO:1902071) 3 0 .30 - < 0.01 1.00E00 1.00E00 postsynaptic neurotransmitter receptor cycle (GO:0099630) 1 0 .10 - < 0.01 1.00E00 1.00E00 isopeptide cross-linking via N6-glycyl-L-lysine (GO:0018276) 1 0 .10 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor diffusion trapping (GO:0099628) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of sphingolipid mediated signaling pathway (GO:1902068) 1 0 .10 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor cycle (GO:0099627) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine (GO:0018272) 1 0 .10 - < 0.01 1.00E00 1.00E00 atrial cardiac muscle cell membrane repolarization (GO:0099624) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of transcription from RNA polymerase II promoter involved in spermatogenesis (GO:1902064) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of glutamate metabolic process (GO:2000212) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of glutamate metabolic process (GO:2000211) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of anoikis (GO:2000210) 4 0 .40 - < 0.01 1.00E00 1.00E00 mismatch repair (GO:0006298) 21 0 2.08 - < 0.01 2.52E-01 1.00E00 nucleotide-excision repair, DNA gap filling (GO:0006297) 5 0 .49 - < 0.01 1.00E00 1.00E00 modulation of signal transduction in other organism (GO:0044501) 1 0 .10 - < 0.01 1.00E00 1.00E00 nucleotide-excision repair, DNA incision, 5'-to lesion (GO:0006296) 3 0 .30 - < 0.01 1.00E00 1.00E00 nucleotide-excision repair, DNA incision, 3'-to lesion (GO:0006295) 3 0 .30 - < 0.01 1.00E00 1.00E00 nucleotide-excision repair, preincision complex assembly (GO:0006294) 1 0 .10 - < 0.01 1.00E00 1.00E00 pyrimidine dimer repair (GO:0006290) 9 0 .89 - < 0.01 1.00E00 1.00E00 regulation of microvillus assembly (GO:0032534) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of microvillus length (GO:0032532) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of microvillus organization (GO:0032530) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 lateral attachment of mitotic spindle microtubules to kinetochore (GO:0099607) 1 0 .10 - < 0.01 1.00E00 1.00E00 polyamine transmembrane transport (GO:1902047) 1 0 .10 - < 0.01 1.00E00 1.00E00 microtubule plus-end directed mitotic chromosome migration (GO:0099606) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of Fas signaling pathway (GO:1902045) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of Fas signaling pathway (GO:1902044) 2 0 .20 - < 0.01 1.00E00 1.00E00 base-excision repair, DNA ligation (GO:0006288) 1 0 .10 - < 0.01 1.00E00 1.00E00 base-excision repair, gap-filling (GO:0006287) 5 0 .49 - < 0.01 1.00E00 1.00E00 base-excision repair, AP site formation (GO:0006285) 5 0 .49 - < 0.01 1.00E00 1.00E00 transcription-coupled nucleotide-excision repair (GO:0006283) 10 0 .99 - < 0.01 1.00E00 1.00E00 protein exit from endoplasmic reticulum (GO:0032527) 21 0 2.08 - < 0.01 2.52E-01 1.00E00 protein-DNA covalent cross-linking repair (GO:0106300) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of hematopoietic stem cell differentiation (GO:1902038) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of hematopoietic stem cell differentiation (GO:1902037) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of hematopoietic stem cell differentiation (GO:1902036) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 positive regulation of hematopoietic stem cell proliferation (GO:1902035) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of hematopoietic stem cell proliferation (GO:1902033) 9 0 .89 - < 0.01 1.00E00 1.00E00 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery (GO:0000973) 2 0 .20 - < 0.01 1.00E00 1.00E00 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery (GO:0000972) 6 0 .59 - < 0.01 1.00E00 1.00E00 RNA-dependent DNA biosynthetic process (GO:0006278) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate (GO:0000971) 1 0 .10 - < 0.01 1.00E00 1.00E00 DNA replication termination (GO:0006274) 1 0 .10 - < 0.01 1.00E00 1.00E00 lagging strand elongation (GO:0006273) 4 0 .40 - < 0.01 1.00E00 1.00E00 leading strand elongation (GO:0006272) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of phosphoprotein phosphatase activity (GO:0032516) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 endosome to lysosome transport via multivesicular body sorting pathway (GO:0032510) 7 0 .69 - < 0.01 1.00E00 1.00E00 tRNA exon ligation (GO:0000968) 1 0 .10 - < 0.01 1.00E00 1.00E00 rRNA 5'-end processing (GO:0000967) 3 0 .30 - < 0.01 1.00E00 1.00E00 L-histidine transport (GO:1902024) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial RNA 3'-end processing (GO:0000965) 5 0 .49 - < 0.01 1.00E00 1.00E00 mitochondrial RNA 5'-end processing (GO:0000964) 3 0 .30 - < 0.01 1.00E00 1.00E00 L-lysine transport (GO:1902022) 3 0 .30 - < 0.01 1.00E00 1.00E00 mitochondrial RNA processing (GO:0000963) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 DNA replication, synthesis of RNA primer (GO:0006269) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial RNA catabolic process (GO:0000962) 3 0 .30 - < 0.01 1.00E00 1.00E00 DNA ligation (GO:0006266) 6 0 .59 - < 0.01 1.00E00 1.00E00 DNA topological change (GO:0006265) 7 0 .69 - < 0.01 1.00E00 1.00E00 mitochondrial DNA replication (GO:0006264) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 mitochondrial mRNA catabolic process (GO:0000958) 3 0 .30 - < 0.01 1.00E00 1.00E00 mitochondrial RNA catabolic process (GO:0000957) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular response to iron(III) ion (GO:0071283) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to iron(II) ion (GO:0071282) 1 0 .10 - < 0.01 1.00E00 1.00E00 UDP-glucose catabolic process (GO:0006258) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of translation in response to endoplasmic reticulum stress (GO:1902010) 2 0 .20 - < 0.01 1.00E00 1.00E00 UDP catabolic process (GO:0006256) 2 0 .20 - < 0.01 1.00E00 1.00E00 CTP catabolic process (GO:0006254) 1 0 .10 - < 0.01 1.00E00 1.00E00 dCTP catabolic process (GO:0006253) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to cobalt ion (GO:0071279) 2 0 .20 - < 0.01 1.00E00 1.00E00 peptidyl-aspartic acid phosphorylation (GO:0018217) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-arginine methylation (GO:0018216) 9 0 .89 - < 0.01 1.00E00 1.00E00 protein carboxylation (GO:0018214) 3 0 .30 - < 0.01 1.00E00 1.00E00 peptidyl-tryptophan modification (GO:0018211) 3 0 .30 - < 0.01 1.00E00 1.00E00 dCMP catabolic process (GO:0006249) 4 0 .40 - < 0.01 1.00E00 1.00E00 CMP catabolic process (GO:0006248) 2 0 .20 - < 0.01 1.00E00 1.00E00 homogentisate catabolic process (GO:1902000) 1 0 .10 - < 0.01 1.00E00 1.00E00 pyrimidine nucleotide catabolic process (GO:0006244) 10 0 .99 - < 0.01 1.00E00 1.00E00 actin filament uncapping (GO:0051695) 2 0 .20 - < 0.01 1.00E00 1.00E00 CTP biosynthetic process (GO:0006241) 8 0 .79 - < 0.01 1.00E00 1.00E00 protein K69-linked ufmylation (GO:1990592) 5 0 .49 - < 0.01 1.00E00 1.00E00 dCDP biosynthetic process (GO:0006240) 1 0 .10 - < 0.01 1.00E00 1.00E00 L-methionine salvage (GO:0071267) 5 0 .49 - < 0.01 1.00E00 1.00E00 peptidyl-methionine modification (GO:0018206) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 L-methionine biosynthetic process (GO:0071265) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of translational initiation in response to starvation (GO:0071264) 2 0 .20 - < 0.01 1.00E00 1.00E00 peptidyl-histidine modification (GO:0018202) 9 0 .89 - < 0.01 1.00E00 1.00E00 regulation of translational initiation in response to starvation (GO:0071262) 2 0 .20 - < 0.01 1.00E00 1.00E00 peptidyl-glycine modification (GO:0018201) 4 0 .40 - < 0.01 1.00E00 1.00E00 peptidyl-glutamic acid modification (GO:0018200) 24 0 2.37 - < 0.01 1.63E-01 1.00E00 dTTP biosynthetic process (GO:0006235) 3 0 .30 - < 0.01 1.00E00 1.00E00 maintenance of ER location (GO:0051685) 1 0 .10 - < 0.01 1.00E00 1.00E00 dTDP biosynthetic process (GO:0006233) 2 0 .20 - < 0.01 1.00E00 1.00E00 maintenance of Golgi location (GO:0051684) 3 0 .30 - < 0.01 1.00E00 1.00E00 dTMP biosynthetic process (GO:0006231) 3 0 .30 - < 0.01 1.00E00 1.00E00 UTP biosynthetic process (GO:0006228) 8 0 .79 - < 0.01 1.00E00 1.00E00 dUDP biosynthetic process (GO:0006227) 3 0 .30 - < 0.01 1.00E00 1.00E00 dUMP biosynthetic process (GO:0006226) 2 0 .20 - < 0.01 1.00E00 1.00E00 UDP biosynthetic process (GO:0006225) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial L-ornithine transmembrane transport (GO:1990575) 3 0 .30 - < 0.01 1.00E00 1.00E00 UMP biosynthetic process (GO:0006222) 2 0 .20 - < 0.01 1.00E00 1.00E00 pyrimidine nucleotide biosynthetic process (GO:0006221) 20 0 1.98 - < 0.01 2.51E-01 1.00E00 pyrimidine nucleotide metabolic process (GO:0006220) 32 0 3.16 - < 0.01 1.12E-01 9.21E-01 division septum assembly (GO:0000917) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to ammonium ion (GO:0071242) 3 0 .30 - < 0.01 1.00E00 1.00E00 actomyosin contractile ring assembly (GO:0000915) 4 0 .40 - < 0.01 1.00E00 1.00E00 glutamatergic neuron differentiation (GO:1905962) 6 0 .59 - < 0.01 1.00E00 1.00E00 assembly of actomyosin apparatus involved in cytokinesis (GO:0000912) 4 0 .40 - < 0.01 1.00E00 1.00E00 uridine catabolic process (GO:0006218) 2 0 .20 - < 0.01 1.00E00 1.00E00 UDP-N-acetylglucosamine transmembrane transport (GO:1990569) 2 0 .20 - < 0.01 1.00E00 1.00E00 cytidine catabolic process (GO:0006216) 2 0 .20 - < 0.01 1.00E00 1.00E00 actin cortical patch localization (GO:0051666) 1 0 .10 - < 0.01 1.00E00 1.00E00 membrane raft localization (GO:0051665) 4 0 .40 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside metabolic process (GO:0006213) 9 0 .89 - < 0.01 1.00E00 1.00E00 nuclear pore localization (GO:0051664) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein polyufmylation (GO:1990564) 5 0 .49 - < 0.01 1.00E00 1.00E00 uracil catabolic process (GO:0006212) 1 0 .10 - < 0.01 1.00E00 1.00E00 5-methylcytosine catabolic process (GO:0006211) 3 0 .30 - < 0.01 1.00E00 1.00E00 thymine catabolic process (GO:0006210) 2 0 .20 - < 0.01 1.00E00 1.00E00 maintenance of centrosome location (GO:0051661) 6 0 .59 - < 0.01 1.00E00 1.00E00 establishment of centrosome localization (GO:0051660) 9 0 .89 - < 0.01 1.00E00 1.00E00 cellular response to antibiotic (GO:0071236) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 regulation of cellular response to alcohol (GO:1905957) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of endothelial tube morphogenesis (GO:1905956) 2 0 .20 - < 0.01 1.00E00 1.00E00 pyrimidine nucleobase catabolic process (GO:0006208) 2 0 .20 - < 0.01 1.00E00 1.00E00 maintenance of mitochondrion location (GO:0051659) 1 0 .10 - < 0.01 1.00E00 1.00E00 'de novo' pyrimidine nucleobase biosynthetic process (GO:0006207) 5 0 .49 - < 0.01 1.00E00 1.00E00 pyrimidine nucleobase metabolic process (GO:0006206) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 maintenance of organelle location (GO:0051657) 10 0 .99 - < 0.01 1.00E00 1.00E00 dGTP catabolic process (GO:0006203) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to tumor cell (GO:0071228) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to muramyl dipeptide (GO:0071225) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of formation of growth cone in injured axon (GO:1905943) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of formation of growth cone in injured axon (GO:1905942) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of gonad development (GO:1905940) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitochondrial FAD transmembrane transport (GO:1990548) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of acid-sensing ion channel activity (GO:1901586) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of acid-sensing ion channel activity (GO:1901585) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitochondrial tricarboxylic acid transmembrane transport (GO:1990546) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial ATP transmembrane transport (GO:1990544) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of telomeric RNA transcription from RNA pol II promoter (GO:1901582) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of telomeric RNA transcription from RNA pol II promoter (GO:1901581) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of telomeric RNA transcription from RNA pol II promoter (GO:1901580) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial manganese ion transmembrane transport (GO:1990540) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to misfolded protein (GO:0071218) 24 0 2.37 - < 0.01 1.63E-01 1.00E00 positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching (GO:1905932) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching (GO:1905931) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching (GO:1905930) 3 0 .30 - < 0.01 1.00E00 1.00E00 barbed-end actin filament uncapping (GO:0051638) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of acetylcholine biosynthetic process (GO:1905923) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of acetylcholine biosynthetic process (GO:1905921) 1 0 .10 - < 0.01 1.00E00 1.00E00 fatty acid derivative catabolic process (GO:1901569) 9 0 .89 - < 0.01 1.00E00 1.00E00 positive regulation of CoA-transferase activity (GO:1905920) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to camptothecin (GO:1901563) 6 0 .59 - < 0.01 1.00E00 1.00E00 bone regeneration (GO:1990523) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to benomyl (GO:1901561) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of CoA-transferase activity (GO:1905918) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of cell differentiation involved in phenotypic switching (GO:1905917) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cell differentiation involved in phenotypic switching (GO:1905916) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of cell differentiation involved in phenotypic switching (GO:1905915) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of calcium ion export across plasma membrane (GO:1905913) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of calcium ion export across plasma membrane (GO:1905912) 2 0 .20 - < 0.01 1.00E00 1.00E00 pyrimidine nucleotide import into mitochondrion (GO:1990519) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of endothelial cell development (GO:1901552) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of endothelial cell development (GO:1901551) 2 0 .20 - < 0.01 1.00E00 1.00E00 replicative senescence (GO:0090399) 10 0 .99 - < 0.01 1.00E00 1.00E00 response to raffinose (GO:1901545) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitotic DNA replication maintenance of fidelity (GO:1990505) 2 0 .20 - < 0.01 1.00E00 1.00E00 dense core granule exocytosis (GO:1990504) 7 0 .69 - < 0.01 1.00E00 1.00E00 dense core granule maturation (GO:1990502) 3 0 .30 - < 0.01 1.00E00 1.00E00 phagosome-lysosome fusion involved in apoptotic cell clearance (GO:0090389) 1 0 .10 - < 0.01 1.00E00 1.00E00 phagolysosome assembly involved in apoptotic cell clearance (GO:0090387) 2 0 .20 - < 0.01 1.00E00 1.00E00 phagosome maturation involved in apoptotic cell clearance (GO:0090386) 2 0 .20 - < 0.01 1.00E00 1.00E00 phagosome-lysosome docking (GO:0090384) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of heart induction (GO:0090381) 4 0 .40 - < 0.01 1.00E00 1.00E00 changes to DNA methylation involved in embryo development (GO:1901538) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of DNA demethylation (GO:1901537) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of DNA demethylation (GO:1901536) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of DNA demethylation (GO:1901535) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of hematopoietic progenitor cell differentiation (GO:1901534) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of cholesterol efflux (GO:0090370) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of mitophagy (GO:1901526) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of mitophagy (GO:1901525) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of mitophagy (GO:1901524) 10 0 .99 - < 0.01 1.00E00 1.00E00 icosanoid catabolic process (GO:1901523) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of mRNA modification (GO:0090367) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of mRNA modification (GO:0090366) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mRNA modification (GO:0090365) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of platelet-derived growth factor production (GO:0090362) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of platelet-derived growth factor production (GO:0090361) 2 0 .20 - < 0.01 1.00E00 1.00E00 phosphatidylserine exposure on apoptotic cell surface (GO:0070782) 7 0 .69 - < 0.01 1.00E00 1.00E00 response to biotin (GO:0070781) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of endothelial tube morphogenesis (GO:1901509) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of acylglycerol transport (GO:1901508) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of acylglycerol transport (GO:1901506) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process (GO:0140196) 1 0 .10 - < 0.01 1.00E00 1.00E00 neuromast hair cell differentiation (GO:0048886) 1 0 .10 - < 0.01 1.00E00 1.00E00 neuromast development (GO:0048884) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular organofluorine metabolic process (GO:0090346) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular organohalogen metabolic process (GO:0090345) 1 0 .10 - < 0.01 1.00E00 1.00E00 lateral line development (GO:0048882) 1 0 .10 - < 0.01 1.00E00 1.00E00 mechanosensory lateral line system development (GO:0048881) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of secretion of lysosomal enzymes (GO:0090341) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of secretion of lysosomal enzymes (GO:0090340) 1 0 .10 - < 0.01 1.00E00 1.00E00 homeostasis of number of retina cells (GO:0048877) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of DNA-dependent DNA replication (GO:0090329) 43 0 4.25 - < 0.01 3.01E-02 4.49E-01 stem cell fate specification (GO:0048866) 1 0 .10 - < 0.01 1.00E00 1.00E00 stem cell fate commitment (GO:0048865) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of locomotion involved in locomotory behavior (GO:0090327) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of locomotion involved in locomotory behavior (GO:0090326) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of locomotion involved in locomotory behavior (GO:0090325) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of oxidative phosphorylation (GO:0090324) 7 0 .69 - < 0.01 1.00E00 1.00E00 formation of anatomical boundary (GO:0048859) 3 0 .30 - < 0.01 1.00E00 1.00E00 brain morphogenesis (GO:0048854) 31 0 3.07 - < 0.01 1.09E-01 9.07E-01 forebrain morphogenesis (GO:0048853) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of DNA methylation-dependent heterochromatin assembly (GO:0090310) 2 0 .20 - < 0.01 1.00E00 1.00E00 cGMP transport (GO:0070731) 1 0 .10 - < 0.01 1.00E00 1.00E00 cAMP transport (GO:0070730) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of ribonucleoprotein complex localization (GO:2000197) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of female gonad development (GO:2000195) 1 0 .10 - < 0.01 1.00E00 1.00E00 ammonium import across plasma membrane (GO:0140157) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of DNA methylation-dependent heterochromatin assembly (GO:0090309) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of DNA methylation-dependent heterochromatin assembly (GO:0090308) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 otolith development (GO:0048840) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of neural crest formation (GO:0090301) 1 0 .10 - < 0.01 1.00E00 1.00E00 cyclic nucleotide transport (GO:0070729) 5 0 .49 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor internalization (GO:0099590) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 positive regulation of progesterone biosynthetic process (GO:2000184) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of androgen biosynthetic process (GO:2000180) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of postsynaptic cytosolic calcium concentration (GO:0099588) 1 0 .10 - < 0.01 1.00E00 1.00E00 mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication (GO:0070716) 1 0 .10 - < 0.01 1.00E00 1.00E00 sodium-dependent organic cation transport (GO:0070715) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA (GO:0106289) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA (GO:0106288) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of pro-T cell differentiation (GO:2000176) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of pro-T cell differentiation (GO:2000174) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of dendrite development (GO:2000171) 7 0 .69 - < 0.01 1.00E00 1.00E00 formation of extrachromosomal circular DNA (GO:0001325) 5 0 .49 - < 0.01 1.00E00 1.00E00 enucleate erythrocyte development (GO:0048822) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of translation at postsynapse, modulating synaptic transmission (GO:0099578) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of translation at presynapse, modulating synaptic transmission (GO:0099577) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of protein catabolic process at postsynapse, modulating synaptic transmission (GO:0099576) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of protein catabolic process at presynapse, modulating synaptic transmission (GO:0099575) 3 0 .30 - < 0.01 1.00E00 1.00E00 detection of peptidoglycan (GO:0032499) 2 0 .20 - < 0.01 1.00E00 1.00E00 detection of muramyl dipeptide (GO:0032498) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of planar cell polarity pathway involved in neural tube closure (GO:2000168) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of planar cell polarity pathway involved in neural tube closure (GO:2000167) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of planar cell polarity pathway involved in pericardium morphogenesis (GO:2000166) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of planar cell polarity pathway involved in pericardium morphogenesis (GO:2000165) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis (GO:2000164) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of hair follicle maturation (GO:0048819) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of planar cell polarity pathway involved in outflow tract morphogenesis (GO:2000163) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of hair follicle maturation (GO:0048818) 2 0 .20 - < 0.01 1.00E00 1.00E00 cytosol to ERGIC protein transport (GO:0106273) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis (GO:2000162) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to ERGIC (GO:0106272) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis (GO:2000161) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of planar cell polarity pathway involved in heart morphogenesis (GO:2000160) 1 0 .10 - < 0.01 1.00E00 1.00E00 age-dependent response to reactive oxygen species (GO:0001315) 1 0 .10 - < 0.01 1.00E00 1.00E00 modification of synaptic structure, modulating synaptic transmission (GO:0099564) 1 0 .10 - < 0.01 1.00E00 1.00E00 maintenance of postsynaptic density structure (GO:0099562) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of Rap protein signal transduction (GO:0032487) 3 0 .30 - < 0.01 1.00E00 1.00E00 Rap protein signal transduction (GO:0032486) 9 0 .89 - < 0.01 1.00E00 1.00E00 regulation of Ral protein signal transduction (GO:0032485) 3 0 .30 - < 0.01 1.00E00 1.00E00 Ral protein signal transduction (GO:0032484) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of planar cell polarity pathway involved in heart morphogenesis (GO:2000159) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of ubiquitin-specific protease activity (GO:2000158) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of ubiquitin-specific protease activity (GO:2000157) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of retrograde vesicle-mediated transport, Golgi to ER (GO:2000156) 2 0 .20 - < 0.01 1.00E00 1.00E00 male genitalia morphogenesis (GO:0048808) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of ubiquitin-specific protease activity (GO:2000152) 4 0 .40 - < 0.01 1.00E00 1.00E00 female genitalia morphogenesis (GO:0048807) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis (GO:2000151) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis (GO:2000150) 1 0 .10 - < 0.01 1.00E00 1.00E00 maintenance of synapse structure (GO:0099558) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission (GO:0099557) 2 0 .20 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by nitric oxide, modulating synaptic transmission (GO:0099555) 2 0 .20 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by soluble gas, modulating synaptic transmission (GO:0099554) 2 0 .20 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by endocannabinoid, modulating synaptic transmission (GO:0099553) 3 0 .30 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by lipid, modulating synaptic transmission (GO:0099552) 3 0 .30 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling, modulating synaptic transmission (GO:0099550) 10 0 .99 - < 0.01 1.00E00 1.00E00 otolith morphogenesis (GO:0032474) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis (GO:2000149) 1 0 .10 - < 0.01 1.00E00 1.00E00 Golgi calcium ion transport (GO:0032472) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of planar cell polarity pathway involved in ventricular septum morphogenesis (GO:2000148) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of endoplasmic reticulum calcium ion concentration (GO:0032470) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of DNA-templated transcription, initiation (GO:2000143) 4 0 .40 - < 0.01 1.00E00 1.00E00 peptidyl-aspartic acid modification (GO:0018197) 3 0 .30 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by nitric oxide (GO:0099548) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of translation at synapse, modulating synaptic transmission (GO:0099547) 7 0 .69 - < 0.01 1.00E00 1.00E00 peptidyl-alanine modification (GO:0018194) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein catabolic process, modulating synaptic transmission (GO:0099546) 1 0 .10 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by trans-synaptic complex (GO:0099545) 6 0 .59 - < 0.01 1.00E00 1.00E00 peptidyl-serine octanoylation (GO:0018191) 1 0 .10 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by soluble gas (GO:0099543) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein octanoylation (GO:0018190) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation by symbiont of host programmed cell death (GO:0052042) 3 0 .30 - < 0.01 1.00E00 1.00E00 Golgi calcium ion homeostasis (GO:0032468) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of cytokinesis (GO:0032466) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of protein homooligomerization (GO:0032464) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of protein homooligomerization (GO:0032463) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein homooligomerization (GO:0032462) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of cell proliferation involved in heart morphogenesis (GO:2000138) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of protein oligomerization (GO:0032460) 1 0 .10 - < 0.01 1.00E00 1.00E00 synaptic signaling via neuropeptide (GO:0099538) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of presynaptic cytosolic calcium concentration (GO:0099533) 1 0 .10 - < 0.01 1.00E00 1.00E00 slow endocytic recycling (GO:0032458) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein depropionylation (GO:0106230) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein nucleotidylation (GO:0018175) 2 0 .20 - < 0.01 1.00E00 1.00E00 modulation by symbiont of host signal transduction pathway (GO:0052027) 1 0 .10 - < 0.01 1.00E00 1.00E00 presynapse to nucleus signaling pathway (GO:0099526) 3 0 .30 - < 0.01 1.00E00 1.00E00 translocation of molecules into host (GO:0044417) 8 0 .79 - < 0.01 1.00E00 1.00E00 presynaptic dense core vesicle exocytosis (GO:0099525) 5 0 .49 - < 0.01 1.00E00 1.00E00 peptidyl-cysteine oxidation (GO:0018171) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein urmylation (GO:0032447) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of sodium-dependent phosphate transport (GO:2000119) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-lysine glutarylation (GO:0106227) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage apoptotic process (GO:2000111) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of macrophage apoptotic process (GO:2000110) 5 0 .49 - < 0.01 1.00E00 1.00E00 dense core granule cytoskeletal transport (GO:0099519) 7 0 .69 - < 0.01 1.00E00 1.00E00 C-terminal protein-tyrosinylation (GO:0018166) 1 0 .10 - < 0.01 1.00E00 1.00E00 cAMP catabolic process (GO:0006198) 1 0 .10 - < 0.01 1.00E00 1.00E00 ITP catabolic process (GO:0006193) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435) 36 0 3.56 - < 0.01 7.23E-02 7.39E-01 regulation of macrophage apoptotic process (GO:2000109) 8 0 .79 - < 0.01 1.00E00 1.00E00 activation of phospholipase A2 activity (GO:0032431) 2 0 .20 - < 0.01 1.00E00 1.00E00 thermosensory behavior (GO:0040040) 1 0 .10 - < 0.01 1.00E00 1.00E00 tRNA C3-cytosine methylation (GO:0106217) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of DNA-dependent DNA replication (GO:2000105) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 negative regulation of DNA-dependent DNA replication (GO:2000104) 10 0 .99 - < 0.01 1.00E00 1.00E00 positive regulation of mammary stem cell proliferation (GO:2000103) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mammary stem cell proliferation (GO:2000101) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein oxidation (GO:0018158) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 regulation of presynaptic cytosolic calcium ion concentration (GO:0099509) 8 0 .79 - < 0.01 1.00E00 1.00E00 calcium-dependent activation of synaptic vesicle fusion (GO:0099502) 2 0 .20 - < 0.01 1.00E00 1.00E00 'de novo' IMP biosynthetic process (GO:0006189) 4 0 .40 - < 0.01 1.00E00 1.00E00 dGDP phosphorylation (GO:0006186) 1 0 .10 - < 0.01 1.00E00 1.00E00 dGDP biosynthetic process (GO:0006185) 1 0 .10 - < 0.01 1.00E00 1.00E00 GTP biosynthetic process (GO:0006183) 10 0 .99 - < 0.01 1.00E00 1.00E00 cGMP biosynthetic process (GO:0006182) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of mismatch repair (GO:0032425) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of mismatch repair (GO:0032423) 3 0 .30 - < 0.01 1.00E00 1.00E00 post-embryonic body morphogenesis (GO:0040032) 1 0 .10 - < 0.01 1.00E00 1.00E00 snRNA modification (GO:0040031) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of molecular function, epigenetic (GO:0040030) 1 0 .10 - < 0.01 1.00E00 1.00E00 nucleic acid-protein covalent cross-linking (GO:0018143) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein-DNA covalent cross-linking (GO:0018142) 1 0 .10 - < 0.01 1.00E00 1.00E00 guanine salvage (GO:0006178) 1 0 .10 - < 0.01 1.00E00 1.00E00 GMP biosynthetic process (GO:0006177) 4 0 .40 - < 0.01 1.00E00 1.00E00 dATP biosynthetic process (GO:0006175) 1 0 .10 - < 0.01 1.00E00 1.00E00 dADP phosphorylation (GO:0006174) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of sodium:proton antiporter activity (GO:0032417) 3 0 .30 - < 0.01 1.00E00 1.00E00 ADP biosynthetic process (GO:0006172) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of sodium:proton antiporter activity (GO:0032416) 1 0 .10 - < 0.01 1.00E00 1.00E00 cAMP biosynthetic process (GO:0006171) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of sodium:proton antiporter activity (GO:0032415) 4 0 .40 - < 0.01 1.00E00 1.00E00 adenine salvage (GO:0006168) 2 0 .20 - < 0.01 1.00E00 1.00E00 AMP biosynthetic process (GO:0006167) 5 0 .49 - < 0.01 1.00E00 1.00E00 purine ribonucleoside salvage (GO:0006166) 5 0 .49 - < 0.01 1.00E00 1.00E00 embryonic cleavage (GO:0040016) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of growth rate (GO:0040010) 4 0 .40 - < 0.01 1.00E00 1.00E00 peptidyl-cysteine methylation (GO:0018125) 2 0 .20 - < 0.01 1.00E00 1.00E00 histone H2A-S1 phosphorylation (GO:0043990) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein adenylylation (GO:0018117) 2 0 .20 - < 0.01 1.00E00 1.00E00 site-specific DNA replication termination at RTS1 barrier (GO:0071171) 1 0 .10 - < 0.01 1.00E00 1.00E00 site-specific DNA replication termination (GO:0071170) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cellular response to very-low-density lipoprotein particle stimulus (GO:1905890) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to hydrostatic pressure (GO:0051599) 5 0 .49 - < 0.01 1.00E00 1.00E00 meiotic recombination checkpoint signaling (GO:0051598) 2 0 .20 - < 0.01 1.00E00 1.00E00 histone H3-S28 phosphorylation (GO:0043988) 3 0 .30 - < 0.01 1.00E00 1.00E00 response to methylmercury (GO:0051597) 2 0 .20 - < 0.01 1.00E00 1.00E00 histone H3-S10 phosphorylation (GO:0043987) 6 0 .59 - < 0.01 1.00E00 1.00E00 methylglyoxal catabolic process (GO:0051596) 5 0 .49 - < 0.01 1.00E00 1.00E00 response to methylglyoxal (GO:0051595) 3 0 .30 - < 0.01 1.00E00 1.00E00 histone H4-R3 methylation (GO:0043985) 2 0 .20 - < 0.01 1.00E00 1.00E00 histone H4-K16 acetylation (GO:0043984) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 histone H4-K12 acetylation (GO:0043983) 8 0 .79 - < 0.01 1.00E00 1.00E00 histone H4-K8 acetylation (GO:0043982) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 histone H4-K5 acetylation (GO:0043981) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 histone H2B-K12 acetylation (GO:0043980) 1 0 .10 - < 0.01 1.00E00 1.00E00 viral translational termination-reinitiation (GO:0075525) 5 0 .49 - < 0.01 1.00E00 1.00E00 IRES-dependent viral translational initiation (GO:0075522) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 establishment of protein localization to chromatin (GO:0071169) 5 0 .49 - < 0.01 1.00E00 1.00E00 protein localization to chromatin (GO:0071168) 22 0 2.18 - < 0.01 2.56E-01 1.00E00 ribonucleoprotein complex localization (GO:0071166) 61 0 6.03 - < 0.01 5.76E-03 1.41E-01 positive regulation of triglyceride transport (GO:1905885) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein C-linked glycosylation (GO:0018103) 3 0 .30 - < 0.01 1.00E00 1.00E00 DNA replication preinitiation complex assembly (GO:0071163) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of triglyceride transport (GO:1905883) 2 0 .20 - < 0.01 1.00E00 1.00E00 histone H2B-K5 acetylation (GO:0043979) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone H2A-K5 acetylation (GO:0043977) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of dopamine uptake involved in synaptic transmission (GO:0051586) 1 0 .10 - < 0.01 1.00E00 1.00E00 dopamine uptake involved in synaptic transmission (GO:0051583) 2 0 .20 - < 0.01 1.00E00 1.00E00 histone H3-K4 acetylation (GO:0043973) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of neurotransmitter uptake (GO:0051582) 2 0 .20 - < 0.01 1.00E00 1.00E00 histone H3-K23 acetylation (GO:0043972) 1 0 .10 - < 0.01 1.00E00 1.00E00 mRNA pseudouridine synthesis (GO:1990481) 7 0 .69 - < 0.01 1.00E00 1.00E00 histone H3-K9 acetylation (GO:0043970) 2 0 .20 - < 0.01 1.00E00 1.00E00 clathrin-dependent endocytosis of virus by host cell (GO:0075512) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of postsynaptic density organization (GO:1905875) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to cell leading edge (GO:1905873) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to cell leading edge (GO:1905872) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein localization to cell leading edge (GO:1905871) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of 3'-UTR-mediated mRNA stabilization (GO:1905870) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of arginine metabolic process (GO:0000821) 3 0 .30 - < 0.01 1.00E00 1.00E00 histone H2B acetylation (GO:0043969) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of glutamine family amino acid metabolic process (GO:0000820) 7 0 .69 - < 0.01 1.00E00 1.00E00 histone H2A acetylation (GO:0043968) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 mitochondrial electron transport, cytochrome c to oxygen (GO:0006123) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 positive regulation of histone H3-K9 methylation (GO:0051574) 9 0 .89 - < 0.01 1.00E00 1.00E00 mitochondrial electron transport, ubiquinol to cytochrome c (GO:0006122) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of histone H3-K9 methylation (GO:0051573) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 mitochondrial electron transport, succinate to ubiquinone (GO:0006121) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of histone H3-K4 methylation (GO:0051572) 6 0 .59 - < 0.01 1.00E00 1.00E00 mitochondrial electron transport, NADH to ubiquinone (GO:0006120) 24 0 2.37 - < 0.01 1.63E-01 1.00E00 positive regulation of histone H3-K4 methylation (GO:0051571) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 regulation of histone H3-K9 methylation (GO:0051570) 23 0 2.27 - < 0.01 2.61E-01 1.00E00 negative regulation of fatty acid beta-oxidation (GO:0031999) 6 0 .59 - < 0.01 1.00E00 1.00E00 endocytosis involved in viral entry into host cell (GO:0075509) 6 0 .59 - < 0.01 1.00E00 1.00E00 entry of viral genome into host nucleus through nuclear pore complex via importin (GO:0075506) 2 0 .20 - < 0.01 1.00E00 1.00E00 mRNA export from nucleus in response to heat stress (GO:0031990) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of 3'-UTR-mediated mRNA stabilization (GO:1905869) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of 3'-UTR-mediated mRNA stabilization (GO:1905868) 6 0 .59 - < 0.01 1.00E00 1.00E00 epididymis development (GO:1905867) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of heparan sulfate proteoglycan binding (GO:1905860) 1 0 .10 - < 0.01 1.00E00 1.00E00 acetaldehyde metabolic process (GO:0006117) 2 0 .20 - < 0.01 1.00E00 1.00E00 glycerol biosynthetic process (GO:0006114) 4 0 .40 - < 0.01 1.00E00 1.00E00 fermentation (GO:0006113) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial calcium ion concentration (GO:0051562) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of cAMP-mediated signaling (GO:0043950) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 bombesin receptor signaling pathway (GO:0031989) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of heparan sulfate proteoglycan binding (GO:1905858) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of pentose-phosphate shunt (GO:1905856) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of heparan sulfate binding (GO:1905855) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of heparan sulfate binding (GO:1905853) 1 0 .10 - < 0.01 1.00E00 1.00E00 malate metabolic process (GO:0006108) 5 0 .49 - < 0.01 1.00E00 1.00E00 fumarate metabolic process (GO:0006106) 2 0 .20 - < 0.01 1.00E00 1.00E00 succinate metabolic process (GO:0006105) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation by host of symbiont catalytic activity (GO:0043947) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrion-endoplasmic reticulum membrane tethering (GO:1990456) 6 0 .59 - < 0.01 1.00E00 1.00E00 succinyl-CoA metabolic process (GO:0006104) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of catalytic activity in other organism involved in symbiotic interaction (GO:0043946) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cysteine metabolic process (GO:1901494) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of lymphangiogenesis (GO:1901492) 3 0 .30 - < 0.01 1.00E00 1.00E00 citrate metabolic process (GO:0006101) 5 0 .49 - < 0.01 1.00E00 1.00E00 flavone metabolic process (GO:0051552) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular stress response to acidic pH (GO:1990451) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cellular response to gamma radiation (GO:1905843) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of keratinocyte migration (GO:0051548) 1 0 .10 - < 0.01 1.00E00 1.00E00 keratinocyte migration (GO:0051546) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of transcription factor catabolic process (GO:1901485) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of elastin biosynthetic process (GO:0051545) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of transcription factor catabolic process (GO:1901483) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of elastin biosynthetic process (GO:0051543) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-threonine autophosphorylation (GO:1990443) 2 0 .20 - < 0.01 1.00E00 1.00E00 elastin biosynthetic process (GO:0051542) 1 0 .10 - < 0.01 1.00E00 1.00E00 intrinsic apoptotic signaling pathway in response to nitrosative stress (GO:1990442) 1 0 .10 - < 0.01 1.00E00 1.00E00 ossification involved in bone remodeling (GO:0043932) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress (GO:1990441) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of telomeric D-loop disassembly (GO:1905839) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of telomeric D-loop disassembly (GO:1905838) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to pyrimidine ribonucleotide (GO:1905835) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to pyrimidine ribonucleotide (GO:1905834) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of microtubule nucleation (GO:1905833) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of spindle assembly (GO:1905832) 4 0 .40 - < 0.01 1.00E00 1.00E00 histone biotinylation (GO:0071110) 1 0 .10 - < 0.01 1.00E00 1.00E00 U6 2'-O-snRNA methylation (GO:1990438) 1 0 .10 - < 0.01 1.00E00 1.00E00 exonucleolytic catabolism of deadenylated mRNA (GO:0043928) 9 0 .89 - < 0.01 1.00E00 1.00E00 snRNA 2'-O-methylation (GO:1990437) 1 0 .10 - < 0.01 1.00E00 1.00E00 pyruvate transmembrane transport (GO:1901475) 3 0 .30 - < 0.01 1.00E00 1.00E00 modulation by host of viral transcription (GO:0043921) 2 0 .20 - < 0.01 1.00E00 1.00E00 mineralocorticoid receptor signaling pathway (GO:0031959) 1 0 .10 - < 0.01 1.00E00 1.00E00 corticosteroid receptor signaling pathway (GO:0031958) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of protein autophosphorylation (GO:0031953) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 superior temporal gyrus development (GO:0071109) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to parathyroid hormone (GO:0071107) 4 0 .40 - < 0.01 1.00E00 1.00E00 response to interleukin-11 (GO:0071105) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to interleukin-9 (GO:0071104) 1 0 .10 - < 0.01 1.00E00 1.00E00 miRNA transport (GO:1990428) 3 0 .30 - < 0.01 1.00E00 1.00E00 mitotic recombination-dependent replication fork processing (GO:1990426) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of glucocorticoid biosynthetic process (GO:0031948) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of glucocorticoid biosynthetic process (GO:0031947) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of glucocorticoid biosynthetic process (GO:0031946) 9 0 .89 - < 0.01 1.00E00 1.00E00 positive regulation of glucocorticoid metabolic process (GO:0031945) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of glucocorticoid metabolic process (GO:0031944) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of glucocorticoid metabolic process (GO:0031943) 10 0 .99 - < 0.01 1.00E00 1.00E00 positive regulation of chromatin silencing at telomere (GO:0031940) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to insulin-like growth factor stimulus (GO:1990418) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to brain-derived neurotrophic factor stimulus (GO:1990416) 4 0 .40 - < 0.01 1.00E00 1.00E00 replication-born double-strand break repair via sister chromatid exchange (GO:1990414) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of unidimensional cell growth (GO:0051511) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of unidimensional cell growth (GO:0051510) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of chromatin silencing at telomere (GO:0031938) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of chromatin silencing (GO:0031937) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of chromatin silencing (GO:0031936) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of chromatin silencing (GO:0031935) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 regulation of neural crest formation (GO:0090299) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial DNA replication (GO:0090298) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial DNA replication (GO:0090297) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitochondria-nucleus signaling pathway (GO:0031930) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial DNA replication (GO:0090296) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of synapse pruning (GO:1905808) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of synapse pruning (GO:1905806) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of osteoclast proliferation (GO:0090291) 1 0 .10 - < 0.01 1.00E00 1.00E00 excitatory synapse pruning (GO:1905805) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of osteoclast proliferation (GO:0090290) 2 0 .20 - < 0.01 1.00E00 1.00E00 embryonic brain development (GO:1990403) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 embryonic lung development (GO:1990401) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of osteoclast proliferation (GO:0090289) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of protein glycosylation in Golgi (GO:0090285) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of protein glycosylation in Golgi (GO:0090284) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein glycosylation in Golgi (GO:0090283) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of transcription involved in G2/M transition of mitotic cell cycle (GO:0090282) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of synaptic plasticity (GO:0031914) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of somatostatin secretion (GO:0090275) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of somatostatin secretion (GO:0090273) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of fibroblast growth factor production (GO:0090272) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of retinal ganglion cell axon guidance (GO:0090260) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of response to alcohol (GO:1901419) 1 0 .10 - < 0.01 1.00E00 1.00E00 proteasome regulatory particle assembly (GO:0070682) 3 0 .30 - < 0.01 1.00E00 1.00E00 glutaminyl-tRNAGln biosynthesis via transamidation (GO:0070681) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial fission (GO:0090258) 4 0 .40 - < 0.01 1.00E00 1.00E00 pronephros development (GO:0048793) 3 0 .30 - < 0.01 1.00E00 1.00E00 spontaneous exocytosis of neurotransmitter (GO:0048792) 1 0 .10 - < 0.01 1.00E00 1.00E00 calcium ion-regulated exocytosis of neurotransmitter (GO:0048791) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 maintenance of presynaptic active zone structure (GO:0048790) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein localization involved in establishment of planar polarity (GO:0090251) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of phosphorylation of RNA polymerase II C-terminal domain (GO:1901409) 1 0 .10 - < 0.01 1.00E00 1.00E00 intralumenal vesicle formation (GO:0070676) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of phosphorylation of RNA polymerase II C-terminal domain (GO:1901407) 2 0 .20 - < 0.01 1.00E00 1.00E00 convergent extension involved in somitogenesis (GO:0090246) 1 0 .10 - < 0.01 1.00E00 1.00E00 axis elongation involved in somitogenesis (GO:0090245) 4 0 .40 - < 0.01 1.00E00 1.00E00 Wnt signaling pathway involved in somitogenesis (GO:0090244) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of histone H4 acetylation (GO:0090240) 6 0 .59 - < 0.01 1.00E00 1.00E00 response to interleukin-2 (GO:0070669) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of mast cell proliferation (GO:0070668) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of mast cell proliferation (GO:0070667) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of mast cell proliferation (GO:0070666) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of arachidonic acid secretion (GO:0090238) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of arachidonic acid secretion (GO:0090237) 7 0 .69 - < 0.01 1.00E00 1.00E00 erythrophore differentiation (GO:0048773) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of metaphase plate congression (GO:0090235) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of kinetochore assembly (GO:0090234) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of centromere complex assembly (GO:0090230) 3 0 .30 - < 0.01 1.00E00 1.00E00 nonfunctional rRNA decay (GO:0070651) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of microtubule nucleation by Ran protein signal transduction (GO:0090226) 1 0 .10 - < 0.01 1.00E00 1.00E00 centrosome-templated microtubule nucleation (GO:0090222) 2 0 .20 - < 0.01 1.00E00 1.00E00 chromosome localization to nuclear envelope involved in homologous chromosome segregation (GO:0090220) 8 0 .79 - < 0.01 1.00E00 1.00E00 vitamin D3 metabolic process (GO:0070640) 6 0 .59 - < 0.01 1.00E00 1.00E00 peptidyl-lysine butyrylation (GO:0140067) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-lysine crotonylation (GO:0140066) 1 0 .10 - < 0.01 1.00E00 1.00E00 pigment granule maturation (GO:0048757) 10 0 .99 - < 0.01 1.00E00 1.00E00 negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity (GO:0090217) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity (GO:0090216) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity (GO:0090215) 4 0 .40 - < 0.01 1.00E00 1.00E00 spongiotrophoblast layer developmental growth (GO:0090214) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of establishment of blood-brain barrier (GO:0090212) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of establishment of blood-brain barrier (GO:0090210) 3 0 .30 - < 0.01 1.00E00 1.00E00 actin cortical patch organization (GO:0044396) 1 0 .10 - < 0.01 1.00E00 1.00E00 transepithelial ammonium transport (GO:0070634) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of smooth muscle cell-matrix adhesion (GO:2000098) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of smooth muscle cell-matrix adhesion (GO:2000097) 5 0 .49 - < 0.01 1.00E00 1.00E00 smooth muscle tissue development (GO:0048745) 22 0 2.18 - < 0.01 2.56E-01 1.00E00 negative regulation of cholesterol metabolic process (GO:0090206) 5 0 .49 - < 0.01 1.00E00 1.00E00 protein localization to nuclear pore (GO:0090204) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of protein kinase activity by regulation of protein phosphorylation (GO:0044387) 7 0 .69 - < 0.01 1.00E00 1.00E00 zymogen granule exocytosis (GO:0070625) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein localization to cytoskeleton (GO:0044380) 43 0 4.25 - < 0.01 3.01E-02 4.49E-01 positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation (GO:2000081) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation (GO:2000080) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular detoxification of methylglyoxal (GO:0140041) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of peroxisome size (GO:0044375) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation (GO:2000079) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of type B pancreatic cell development (GO:2000078) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of type B pancreatic cell development (GO:2000077) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of type B pancreatic cell development (GO:2000074) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of molecular function in other organism (GO:0044362) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of centromeric sister chromatid cohesion (GO:0070602) 3 0 .30 - < 0.01 1.00E00 1.00E00 centromeric sister chromatid cohesion (GO:0070601) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of cortisol biosynthetic process (GO:2000066) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cortisol biosynthetic process (GO:2000065) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of cortisol biosynthetic process (GO:2000064) 7 0 .69 - < 0.01 1.00E00 1.00E00 mitochondrial ADP transmembrane transport (GO:0140021) 3 0 .30 - < 0.01 1.00E00 1.00E00 modulation of molecular function in other organism (GO:0044359) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of rRNA stability (GO:0044357) 1 0 .10 - < 0.01 1.00E00 1.00E00 macropinocytosis (GO:0044351) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of intracellular cholesterol transport (GO:0032385) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of intracellular cholesterol transport (GO:0032384) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of intracellular cholesterol transport (GO:0032383) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of intracellular sterol transport (GO:0032382) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of intracellular sterol transport (GO:0032381) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis (GO:2000057) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of intracellular sterol transport (GO:0032380) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of Wnt signaling pathway involved in digestive tract morphogenesis (GO:2000056) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification (GO:2000054) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification (GO:2000053) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of non-canonical Wnt signaling pathway (GO:2000051) 8 0 .79 - < 0.01 1.00E00 1.00E00 histone displacement (GO:0001207) 1 0 .10 - < 0.01 1.00E00 1.00E00 embryonic viscerocranium morphogenesis (GO:0048703) 8 0 .79 - < 0.01 1.00E00 1.00E00 embryonic neurocranium morphogenesis (GO:0048702) 9 0 .89 - < 0.01 1.00E00 1.00E00 fibroblast apoptotic process (GO:0044346) 2 0 .20 - < 0.01 1.00E00 1.00E00 stromal-epithelial cell signaling involved in prostate gland development (GO:0044345) 1 0 .10 - < 0.01 1.00E00 1.00E00 sodium-dependent phosphate transport (GO:0044341) 1 0 .10 - < 0.01 1.00E00 1.00E00 canonical Wnt signaling pathway involved in regulation of cell proliferation (GO:0044340) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of intracellular lipid transport (GO:0032379) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of intracellular lipid transport (GO:0032378) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of intracellular lipid transport (GO:0032377) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac cell fate specification (GO:2000044) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cardiac cell fate specification (GO:2000043) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of planar cell polarity pathway involved in axis elongation (GO:2000041) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of planar cell polarity pathway involved in axis elongation (GO:2000040) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein polyglutamylation (GO:0018095) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 canonical Wnt signaling pathway involved in osteoblast differentiation (GO:0044339) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein polyglycylation (GO:0018094) 2 0 .20 - < 0.01 1.00E00 1.00E00 canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation (GO:0044338) 2 0 .20 - < 0.01 1.00E00 1.00E00 canonical Wnt signaling pathway involved in positive regulation of apoptotic process (GO:0044337) 2 0 .20 - < 0.01 1.00E00 1.00E00 canonical Wnt signaling pathway involved in negative regulation of apoptotic process (GO:0044336) 4 0 .40 - < 0.01 1.00E00 1.00E00 canonical Wnt signaling pathway involved in neural crest cell differentiation (GO:0044335) 1 0 .10 - < 0.01 1.00E00 1.00E00 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition (GO:0044334) 2 0 .20 - < 0.01 1.00E00 1.00E00 cell-cell adhesion mediated by cadherin (GO:0044331) 7 0 .69 - < 0.01 1.00E00 1.00E00 canonical Wnt signaling pathway involved in positive regulation of wound healing (GO:0044330) 1 0 .10 - < 0.01 1.00E00 1.00E00 oxygen homeostasis (GO:0032364) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of stem cell population maintenance (GO:2000036) 30 0 2.97 - < 0.01 1.07E-01 8.99E-01 canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion (GO:0044329) 1 0 .10 - < 0.01 1.00E00 1.00E00 canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration (GO:0044328) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of glycine import across plasma membrane (GO:1900925) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle cell contraction (GO:0106134) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of male gonad development (GO:2000020) 4 0 .40 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-lysine acetylation (GO:0018076) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein K27-linked ubiquitination (GO:0044314) 5 0 .49 - < 0.01 1.00E00 1.00E00 protein K6-linked deubiquitination (GO:0044313) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of aldosterone biosynthetic process (GO:0032349) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of aldosterone biosynthetic process (GO:0032348) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of aldosterone biosynthetic process (GO:0032347) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of aldosterone metabolic process (GO:0032346) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of aldosterone metabolic process (GO:0032345) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of aldosterone metabolic process (GO:0032344) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of male gonad development (GO:2000019) 1 0 .10 - < 0.01 1.00E00 1.00E00 aldosterone biosynthetic process (GO:0032342) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of male gonad development (GO:2000018) 6 0 .59 - < 0.01 1.00E00 1.00E00 aldosterone metabolic process (GO:0032341) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of determination of dorsal identity (GO:2000016) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of adaxial/abaxial pattern formation (GO:2000011) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of cobalamin metabolic process (GO:0106121) 1 0 .10 - < 0.01 1.00E00 1.00E00 cytochrome c-heme linkage (GO:0018063) 1 0 .10 - < 0.01 1.00E00 1.00E00 pentose-phosphate shunt (GO:0006098) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of sterol biosynthetic process (GO:0106119) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of metanephric comma-shaped body morphogenesis (GO:2000007) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of metanephric comma-shaped body morphogenesis (GO:2000006) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of metanephric S-shaped body morphogenesis (GO:2000005) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of metanephric S-shaped body morphogenesis (GO:2000004) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of DNA damage checkpoint (GO:2000003) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of DNA damage checkpoint (GO:2000002) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of DNA damage checkpoint (GO:2000001) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 peptidyl-lysine oxidation (GO:0018057) 4 0 .40 - < 0.01 1.00E00 1.00E00 acetyl-CoA biosynthetic process from pyruvate (GO:0006086) 7 0 .69 - < 0.01 1.00E00 1.00E00 acetyl-CoA biosynthetic process (GO:0006085) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 acetate metabolic process (GO:0006083) 3 0 .30 - < 0.01 1.00E00 1.00E00 molybdopterin cofactor biosynthetic process (GO:0032324) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of glutamate receptor clustering (GO:0106104) 8 0 .79 - < 0.01 1.00E00 1.00E00 ER-dependent peroxisome localization (GO:0106101) 1 0 .10 - < 0.01 1.00E00 1.00E00 prostaglandin secretion (GO:0032310) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein amidation (GO:0018032) 1 0 .10 - < 0.01 1.00E00 1.00E00 ethanol oxidation (GO:0006069) 2 0 .20 - < 0.01 1.00E00 1.00E00 ethanol catabolic process (GO:0006068) 2 0 .20 - < 0.01 1.00E00 1.00E00 ethanol metabolic process (GO:0006067) 2 0 .20 - < 0.01 1.00E00 1.00E00 UDP-glucuronate biosynthetic process (GO:0006065) 1 0 .10 - < 0.01 1.00E00 1.00E00 glucuronate catabolic process (GO:0006064) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of prostaglandin secretion (GO:0032307) 2 0 .20 - < 0.01 1.00E00 1.00E00 sorbitol biosynthetic process (GO:0006061) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of icosanoid secretion (GO:0032304) 4 0 .40 - < 0.01 1.00E00 1.00E00 peptidyl-lysine dimethylation (GO:0018027) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 peptidyl-lysine monomethylation (GO:0018026) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 peptidyl-lysine trimethylation (GO:0018023) 32 0 3.16 - < 0.01 1.12E-01 9.20E-01 peptidyl-histidine methylation (GO:0018021) 2 0 .20 - < 0.01 1.00E00 1.00E00 mannoprotein biosynthetic process (GO:0006057) 1 0 .10 - < 0.01 1.00E00 1.00E00 mannoprotein metabolic process (GO:0006056) 1 0 .10 - < 0.01 1.00E00 1.00E00 CMP-N-acetylneuraminate biosynthetic process (GO:0006055) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of intraciliary retrograde transport (GO:1905799) 2 0 .20 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-proline dimethylation (GO:0018016) 1 0 .10 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-glycine methylation (GO:0018013) 1 0 .10 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-alanine trimethylation (GO:0018012) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to pericentriolar material (GO:1905793) 2 0 .20 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-alanine methylation (GO:0018011) 1 0 .10 - < 0.01 1.00E00 1.00E00 UDP-N-acetylglucosamine catabolic process (GO:0006049) 1 0 .10 - < 0.01 1.00E00 1.00E00 UDP-N-acetylglucosamine biosynthetic process (GO:0006048) 6 0 .59 - < 0.01 1.00E00 1.00E00 UDP-N-acetylglucosamine metabolic process (GO:0006047) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 N-acetylglucosamine catabolic process (GO:0006046) 3 0 .30 - < 0.01 1.00E00 1.00E00 glucosamine catabolic process (GO:0006043) 2 0 .20 - < 0.01 1.00E00 1.00E00 glucosamine biosynthetic process (GO:0006042) 1 0 .10 - < 0.01 1.00E00 1.00E00 glucosamine metabolic process (GO:0006041) 5 0 .49 - < 0.01 1.00E00 1.00E00 AMPA selective glutamate receptor signaling pathway (GO:0098990) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein K33-linked ubiquitination (GO:1990390) 1 0 .10 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-glycine N-myristoylation (GO:0018008) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of detection of mechanical stimulus involved in sensory perception of touch (GO:1905788) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of detection of mechanical stimulus involved in sensory perception of touch (GO:1905787) 1 0 .10 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-glutamic acid acetylation (GO:0018002) 2 0 .20 - < 0.01 1.00E00 1.00E00 removal of nonhomologous ends (GO:0000735) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of phosphatidylserine exposure on apoptotic cell surface (GO:1905782) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell wall chitin catabolic process (GO:0006039) 1 0 .10 - < 0.01 1.00E00 1.00E00 NMDA selective glutamate receptor signaling pathway (GO:0098989) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of phosphatidylserine exposure on apoptotic cell surface (GO:1905780) 1 0 .10 - < 0.01 1.00E00 1.00E00 strand displacement (GO:0000732) 1 0 .10 - < 0.01 1.00E00 1.00E00 DNA synthesis involved in DNA repair (GO:0000731) 27 0 2.67 - < 0.01 1.68E-01 1.00E00 cell wall chitin metabolic process (GO:0006037) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitotic cleavage furrow ingression (GO:1990386) 1 0 .10 - < 0.01 1.00E00 1.00E00 hyaloid vascular plexus regression (GO:1990384) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of exonuclease activity (GO:1905778) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of exonuclease activity (GO:1905777) 2 0 .20 - < 0.01 1.00E00 1.00E00 DNA double-strand break processing (GO:0000729) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 positive regulation of DNA helicase activity (GO:1905776) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of DNA helicase activity (GO:1905775) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of DNA helicase activity (GO:1905774) 5 0 .49 - < 0.01 1.00E00 1.00E00 polyadenylation-dependent snoRNA 3'-end processing (GO:0071051) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of mesodermal cell differentiation (GO:1905772) 2 0 .20 - < 0.01 1.00E00 1.00E00 sno(s)RNA polyadenylation (GO:0071050) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of mesodermal cell differentiation (GO:1905771) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of mesodermal cell differentiation (GO:1905770) 7 0 .69 - < 0.01 1.00E00 1.00E00 telomere maintenance via recombination (GO:0000722) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 inhibitory chemical synaptic transmission (GO:0098977) 1 0 .10 - < 0.01 1.00E00 1.00E00 pyrimidine dimer repair by nucleotide-excision repair (GO:0000720) 4 0 .40 - < 0.01 1.00E00 1.00E00 excitatory chemical synaptic transmission (GO:0098976) 3 0 .30 - < 0.01 1.00E00 1.00E00 inositol biosynthetic process (GO:0006021) 1 0 .10 - < 0.01 1.00E00 1.00E00 anterograde dendritic transport of neurotransmitter receptor complex (GO:0098971) 5 0 .49 - < 0.01 1.00E00 1.00E00 inositol metabolic process (GO:0006020) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 postsynaptic neurotransmitter receptor diffusion trapping (GO:0098970) 5 0 .49 - < 0.01 1.00E00 1.00E00 nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription (GO:0071049) 2 0 .20 - < 0.01 1.00E00 1.00E00 nuclear retention of unspliced pre-mRNA at the site of transcription (GO:0071048) 2 0 .20 - < 0.01 1.00E00 1.00E00 polyadenylation-dependent mRNA catabolic process (GO:0071047) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of double-stranded telomeric DNA binding (GO:1905768) 1 0 .10 - < 0.01 1.00E00 1.00E00 nuclear polyadenylation-dependent ncRNA catabolic process (GO:0071046) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of double-stranded telomeric DNA binding (GO:1905767) 1 0 .10 - < 0.01 1.00E00 1.00E00 nuclear histone mRNA catabolic process (GO:0071045) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone mRNA catabolic process (GO:0071044) 10 0 .99 - < 0.01 1.00E00 1.00E00 negative regulation of protection from non-homologous end joining at telomere (GO:1905765) 4 0 .40 - < 0.01 1.00E00 1.00E00 nucleotide-excision repair, DNA duplex unwinding (GO:0000717) 2 0 .20 - < 0.01 1.00E00 1.00E00 CUT metabolic process (GO:0071043) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of protection from non-homologous end joining at telomere (GO:1905764) 4 0 .40 - < 0.01 1.00E00 1.00E00 nuclear polyadenylation-dependent mRNA catabolic process (GO:0071042) 4 0 .40 - < 0.01 1.00E00 1.00E00 nucleotide-excision repair, DNA damage recognition (GO:0000715) 3 0 .30 - < 0.01 1.00E00 1.00E00 antisense RNA transcript catabolic process (GO:0071041) 1 0 .10 - < 0.01 1.00E00 1.00E00 nuclear polyadenylation-dependent antisense transcript catabolic process (GO:0071040) 1 0 .10 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor transport to postsynaptic membrane (GO:0098969) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 neurotransmitter receptor transport postsynaptic membrane to endosome (GO:0098968) 1 0 .10 - < 0.01 1.00E00 1.00E00 meiotic DNA repair synthesis (GO:0000711) 1 0 .10 - < 0.01 1.00E00 1.00E00 exocytic insertion of neurotransmitter receptor to postsynaptic membrane (GO:0098967) 7 0 .69 - < 0.01 1.00E00 1.00E00 meiotic mismatch repair (GO:0000710) 5 0 .49 - < 0.01 1.00E00 1.00E00 5-phosphoribose 1-diphosphate biosynthetic process (GO:0006015) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of corticotropin-releasing hormone secretion (GO:0051466) 3 0 .30 - < 0.01 1.00E00 1.00E00 D-ribose metabolic process (GO:0006014) 3 0 .30 - < 0.01 1.00E00 1.00E00 mannose metabolic process (GO:0006013) 10 0 .99 - < 0.01 1.00E00 1.00E00 positive regulation of cortisol secretion (GO:0051464) 1 0 .10 - < 0.01 1.00E00 1.00E00 galactose metabolic process (GO:0006012) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of cortisol secretion (GO:0051463) 1 0 .10 - < 0.01 1.00E00 1.00E00 UDP-glucose metabolic process (GO:0006011) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of cortisol secretion (GO:0051462) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of corticotropin secretion (GO:0051461) 5 0 .49 - < 0.01 1.00E00 1.00E00 nuclear polyadenylation-dependent CUT catabolic process (GO:0071039) 1 0 .10 - < 0.01 1.00E00 1.00E00 nuclear polyadenylation-dependent tRNA catabolic process (GO:0071038) 6 0 .59 - < 0.01 1.00E00 1.00E00 nuclear polyadenylation-dependent snRNA catabolic process (GO:0071037) 1 0 .10 - < 0.01 1.00E00 1.00E00 nuclear polyadenylation-dependent snoRNA catabolic process (GO:0071036) 1 0 .10 - < 0.01 1.00E00 1.00E00 nuclear polyadenylation-dependent rRNA catabolic process (GO:0071035) 6 0 .59 - < 0.01 1.00E00 1.00E00 CUT catabolic process (GO:0071034) 4 0 .40 - < 0.01 1.00E00 1.00E00 nuclear retention of pre-mRNA at the site of transcription (GO:0071033) 5 0 .49 - < 0.01 1.00E00 1.00E00 meiotic DNA double-strand break processing (GO:0000706) 3 0 .30 - < 0.01 1.00E00 1.00E00 nuclear mRNA surveillance of mRNA 3'-end processing (GO:0071031) 2 0 .20 - < 0.01 1.00E00 1.00E00 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing (GO:0071030) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of endosome to plasma membrane protein transport (GO:1905751) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of cardioblast cell fate specification (GO:0009997) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of corticotropin secretion (GO:0051459) 5 0 .49 - < 0.01 1.00E00 1.00E00 retrograde axonal transport of mitochondrion (GO:0098958) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of transforming growth factor beta3 activation (GO:1901398) 1 0 .10 - < 0.01 1.00E00 1.00E00 glucose catabolic process (GO:0006007) 10 0 .99 - < 0.01 1.00E00 1.00E00 fucose metabolic process (GO:0006004) 6 0 .59 - < 0.01 1.00E00 1.00E00 monopolar spindle attachment to meiosis I kinetochore (GO:0051455) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of transforming growth factor beta1 activation (GO:1901394) 1 0 .10 - < 0.01 1.00E00 1.00E00 receptor diffusion trapping (GO:0098953) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of transforming growth factor beta1 activation (GO:1901392) 1 0 .10 - < 0.01 1.00E00 1.00E00 fructose catabolic process (GO:0006001) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of transforming growth factor beta activation (GO:1901390) 1 0 .10 - < 0.01 1.00E00 1.00E00 nuclear ncRNA surveillance (GO:0071029) 6 0 .59 - < 0.01 1.00E00 1.00E00 nuclear mRNA surveillance (GO:0071028) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 regulation of endosome to plasma membrane protein transport (GO:1905749) 5 0 .49 - < 0.01 1.00E00 1.00E00 nuclear RNA surveillance (GO:0071027) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 cytoplasmic RNA surveillance (GO:0071026) 1 0 .10 - < 0.01 1.00E00 1.00E00 RNA surveillance (GO:0071025) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 negative regulation of transforming growth factor beta activation (GO:1901389) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of transforming growth factor beta activation (GO:1901388) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of voltage-gated calcium channel activity (GO:1901387) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 negative regulation of meiotic cell cycle (GO:0051447) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 negative regulation of ubiquitin-protein transferase activity (GO:0051444) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 neurotransmitter receptor transport, postsynaptic endosome to lysosome (GO:0098943) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of chorionic trophoblast cell proliferation (GO:1901383) 1 0 .10 - < 0.01 1.00E00 1.00E00 retrograde trans-synaptic signaling by trans-synaptic protein complex (GO:0098942) 3 0 .30 - < 0.01 1.00E00 1.00E00 telomeric 3' overhang formation (GO:0031860) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of L-proline import across plasma membrane (GO:1905737) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of L-proline import across plasma membrane (GO:1905735) 1 0 .10 - < 0.01 1.00E00 1.00E00 organic heteropentacyclic compound catabolic process (GO:1901377) 2 0 .20 - < 0.01 1.00E00 1.00E00 organic heteropentacyclic compound metabolic process (GO:1901376) 2 0 .20 - < 0.01 1.00E00 1.00E00 acetate ester transport (GO:1901374) 2 0 .20 - < 0.01 1.00E00 1.00E00 cytidine deamination (GO:0009972) 2 0 .20 - < 0.01 1.00E00 1.00E00 lipid hydroperoxide transport (GO:1901373) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to microtubule end (GO:1905725) 4 0 .40 - < 0.01 1.00E00 1.00E00 presynaptic signal transduction (GO:0098928) 3 0 .30 - < 0.01 1.00E00 1.00E00 retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission (GO:0098925) 1 0 .10 - < 0.01 1.00E00 1.00E00 retrograde trans-synaptic signaling by nitric oxide (GO:0098924) 2 0 .20 - < 0.01 1.00E00 1.00E00 retrograde trans-synaptic signaling by soluble gas (GO:0098923) 2 0 .20 - < 0.01 1.00E00 1.00E00 retrograde trans-synaptic signaling by endocannabinoid (GO:0098921) 3 0 .30 - < 0.01 1.00E00 1.00E00 retrograde trans-synaptic signaling by lipid (GO:0098920) 3 0 .30 - < 0.01 1.00E00 1.00E00 protection from non-homologous end joining at telomere (GO:0031848) 6 0 .59 - < 0.01 1.00E00 1.00E00 protein localization to perinuclear region of cytoplasm (GO:1905719) 8 0 .79 - < 0.01 1.00E00 1.00E00 response to phosphatidylethanolamine (GO:1905711) 1 0 .10 - < 0.01 1.00E00 1.00E00 epidermal cell fate specification (GO:0009957) 3 0 .30 - < 0.01 1.00E00 1.00E00 microtubule nucleation by microtubule organizing center (GO:0051418) 5 0 .49 - < 0.01 1.00E00 1.00E00 retrograde trans-synaptic signaling (GO:0098917) 8 0 .79 - < 0.01 1.00E00 1.00E00 response to rapamycin (GO:1901355) 4 0 .40 - < 0.01 1.00E00 1.00E00 microtubule nucleation by interphase microtubule organizing center (GO:0051415) 1 0 .10 - < 0.01 1.00E00 1.00E00 membrane repolarization during atrial cardiac muscle cell action potential (GO:0098914) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to cortisol (GO:0051414) 1 0 .10 - < 0.01 1.00E00 1.00E00 membrane depolarization during atrial cardiac muscle cell action potential (GO:0098912) 2 0 .20 - < 0.01 1.00E00 1.00E00 dorsal/ventral axis specification (GO:0009950) 10 0 .99 - < 0.01 1.00E00 1.00E00 response to corticosterone (GO:0051412) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of atrial cardiac muscle cell action potential (GO:0098910) 2 0 .20 - < 0.01 1.00E00 1.00E00 detoxification of nitrogen compound (GO:0051410) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of membrane permeability (GO:1905709) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of glomerulus development (GO:0090194) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of glomerulus development (GO:0090193) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of glomerulus development (GO:0090192) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial ATP synthesis coupled proton transport (GO:1905706) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of branching involved in ureteric bud morphogenesis (GO:0090191) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of inhibitory synapse assembly (GO:1905703) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle cell action potential involved in regulation of contraction (GO:0098909) 3 0 .30 - < 0.01 1.00E00 1.00E00 response to nitrosative stress (GO:0051409) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of neuronal action potential (GO:0098908) 7 0 .69 - < 0.01 1.00E00 1.00E00 proximal/distal axis specification (GO:0009946) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of SA node cell action potential (GO:0098907) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of vasculature development involved in avascular cornea development in camera-type eye (GO:1901346) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of bundle of His cell action potential (GO:0098905) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of AV node cell action potential (GO:0098904) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to leptomycin B (GO:1901344) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of membrane repolarization during action potential (GO:0098903) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of membrane depolarization during action potential (GO:0098902) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of store-operated calcium channel activity (GO:1901340) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of pancreatic juice secretion (GO:0090187) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of kidney development (GO:0090185) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of kidney development (GO:0090184) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of secretion of lysosomal enzymes (GO:0090182) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of odontoblast differentiation (GO:1901331) 1 0 .10 - < 0.01 1.00E00 1.00E00 planar cell polarity pathway involved in neural tube closure (GO:0090179) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 establishment of planar polarity involved in neural tube closure (GO:0090177) 1 0 .10 - < 0.01 1.00E00 1.00E00 microtubule cytoskeleton organization involved in establishment of planar polarity (GO:0090176) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of Golgi inheritance (GO:0090170) 4 0 .40 - < 0.01 1.00E00 1.00E00 response to cytochalasin B (GO:1901328) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of heart induction (GO:1901321) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of heart induction (GO:1901320) 1 0 .10 - < 0.01 1.00E00 1.00E00 Golgi reassembly (GO:0090168) 4 0 .40 - < 0.01 1.00E00 1.00E00 Golgi disassembly (GO:0090166) 7 0 .69 - < 0.01 1.00E00 1.00E00 asymmetric Golgi ribbon formation (GO:0090164) 2 0 .20 - < 0.01 1.00E00 1.00E00 Golgi to lysosome transport (GO:0090160) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 cellular component macromolecule biosynthetic process (GO:0070589) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell-cell adhesion involved in gastrulation (GO:0070586) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of sterol regulatory element binding protein cleavage (GO:1901310) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of collateral sprouting in absence of injury (GO:0048697) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of collateral sprouting in absence of injury (GO:0048696) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular sphingolipid homeostasis (GO:0090156) 6 0 .59 - < 0.01 1.00E00 1.00E00 maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter (GO:0001193) 1 0 .10 - < 0.01 1.00E00 1.00E00 maintenance of transcriptional fidelity during DNA-templated transcription elongation (GO:0001192) 1 0 .10 - < 0.01 1.00E00 1.00E00 establishment of protein localization to mitochondrial membrane involved in mitochondrial fission (GO:0090152) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of sterol regulatory element binding protein cleavage (GO:1901308) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of spermidine biosynthetic process (GO:1901307) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of neuron projection regeneration (GO:0070571) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 regulation of spermidine biosynthetic process (GO:1901304) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cargo loading into COPII-coated vesicle (GO:1901303) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of cargo loading into COPII-coated vesicle (GO:1901301) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of hydrogen peroxide-mediated programmed cell death (GO:1901300) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of sprouting of injured axon (GO:0048688) 1 0 .10 - < 0.01 1.00E00 1.00E00 RNA polymerase I preinitiation complex assembly (GO:0001188) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitochondrial membrane fission (GO:0090149) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of collateral sprouting of intact axon in response to injury (GO:0048683) 1 0 .10 - < 0.01 1.00E00 1.00E00 sprouting of injured axon (GO:0048682) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial nucleoid organization (GO:0090144) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of axon regeneration (GO:0048681) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 nucleoid organization (GO:0090143) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of vitamin D receptor signaling pathway (GO:0070564) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of vitamin D receptor signaling pathway (GO:0070563) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of vitamin D receptor signaling pathway (GO:0070562) 7 0 .69 - < 0.01 1.00E00 1.00E00 vitamin D receptor signaling pathway (GO:0070561) 2 0 .20 - < 0.01 1.00E00 1.00E00 axon extension involved in regeneration (GO:0048677) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of actin cytoskeleton organization by cell-cell adhesion (GO:0090138) 1 0 .10 - < 0.01 1.00E00 1.00E00 transcriptional start site selection at RNA polymerase II promoter (GO:0001174) 1 0 .10 - < 0.01 1.00E00 1.00E00 actin filament branching (GO:0090135) 3 0 .30 - < 0.01 1.00E00 1.00E00 DNA-templated transcriptional start site selection (GO:0001173) 1 0 .10 - < 0.01 1.00E00 1.00E00 transcription, RNA-templated (GO:0001172) 1 0 .10 - < 0.01 1.00E00 1.00E00 mesenchyme migration (GO:0090131) 1 0 .10 - < 0.01 1.00E00 1.00E00 detection of mechanical stimulus involved in sensory perception of touch (GO:0050976) 1 0 .10 - < 0.01 1.00E00 1.00E00 sensory perception of touch (GO:0050975) 4 0 .40 - < 0.01 1.00E00 1.00E00 detection of mechanical stimulus involved in equilibrioception (GO:0050973) 1 0 .10 - < 0.01 1.00E00 1.00E00 neuron fate determination (GO:0048664) 3 0 .30 - < 0.01 1.00E00 1.00E00 detection of chemical stimulus involved in sensory perception of pain (GO:0050968) 1 0 .10 - < 0.01 1.00E00 1.00E00 detection of calcium ion (GO:0005513) 3 0 .30 - < 0.01 1.00E00 1.00E00 smooth muscle cell proliferation (GO:0048659) 5 0 .49 - < 0.01 1.00E00 1.00E00 detection of light stimulus involved in sensory perception (GO:0050962) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 detection of temperature stimulus involved in thermoception (GO:0050960) 1 0 .10 - < 0.01 1.00E00 1.00E00 vesicle-mediated cholesterol transport (GO:0090119) 2 0 .20 - < 0.01 1.00E00 1.00E00 receptor-mediated endocytosis involved in cholesterol transport (GO:0090118) 3 0 .30 - < 0.01 1.00E00 1.00E00 endosome to lysosome transport of low-density lipoprotein particle (GO:0090117) 1 0 .10 - < 0.01 1.00E00 1.00E00 C-5 methylation of cytosine (GO:0090116) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis (GO:0090113) 3 0 .30 - < 0.01 1.00E00 1.00E00 COPII-coated vesicle cargo loading (GO:0090110) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 histone H2A K63-linked deubiquitination (GO:0070537) 3 0 .30 - < 0.01 1.00E00 1.00E00 histone H2A K63-linked ubiquitination (GO:0070535) 2 0 .20 - < 0.01 1.00E00 1.00E00 equilibrioception (GO:0050957) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of high-density lipoprotein particle assembly (GO:0090108) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of high-density lipoprotein particle assembly (GO:0090107) 3 0 .30 - < 0.01 1.00E00 1.00E00 pancreatic epsilon cell differentiation (GO:0090104) 1 0 .10 - < 0.01 1.00E00 1.00E00 tRNA threonylcarbamoyladenosine metabolic process (GO:0070525) 10 0 .99 - < 0.01 1.00E00 1.00E00 response to ceramide (GO:0106096) 1 0 .10 - < 0.01 1.00E00 1.00E00 glial cell projection elongation (GO:0106091) 2 0 .20 - < 0.01 1.00E00 1.00E00 skeletal muscle tissue growth (GO:0048630) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of histone H4-K20 methylation (GO:0070512) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of histone H4-K20 methylation (GO:0070510) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cell adhesion involved in sprouting angiogenesis (GO:0106089) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cell adhesion involved in sprouting angiogenesis (GO:0106088) 1 0 .10 - < 0.01 1.00E00 1.00E00 myoblast development (GO:0048627) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein-DNA complex remodeling (GO:0001120) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of DNA-dependent DNA replication initiation (GO:0032298) 2 0 .20 - < 0.01 1.00E00 1.00E00 poly-gamma-glutamate metabolic process (GO:0070500) 1 0 .10 - < 0.01 1.00E00 1.00E00 induction of negative chemotaxis (GO:0050929) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of positive chemotaxis (GO:0050928) 1 0 .10 - < 0.01 1.00E00 1.00E00 peripheral nervous system myelin formation (GO:0032290) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of negative chemotaxis (GO:0050925) 2 0 .20 - < 0.01 1.00E00 1.00E00 histone succinylation (GO:0106077) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of negative chemotaxis (GO:0050924) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial RNA modification (GO:1900864) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of negative chemotaxis (GO:0050923) 4 0 .40 - < 0.01 1.00E00 1.00E00 embryonic hindgut morphogenesis (GO:0048619) 3 0 .30 - < 0.01 1.00E00 1.00E00 aminoacyl-tRNA metabolism involved in translational fidelity (GO:0106074) 1 0 .10 - < 0.01 1.00E00 1.00E00 embryonic foregut morphogenesis (GO:0048617) 8 0 .79 - < 0.01 1.00E00 1.00E00 embryonic ectodermal digestive tract morphogenesis (GO:0048613) 1 0 .10 - < 0.01 1.00E00 1.00E00 transcription open complex formation at RNA polymerase II promoter (GO:0001113) 1 0 .10 - < 0.01 1.00E00 1.00E00 DNA-templated transcription open complex formation (GO:0001112) 2 0 .20 - < 0.01 1.00E00 1.00E00 embryonic ectodermal digestive tract development (GO:0048611) 2 0 .20 - < 0.01 1.00E00 1.00E00 sensory perception of umami taste (GO:0050917) 4 0 .40 - < 0.01 1.00E00 1.00E00 sensory perception of sweet taste (GO:0050916) 3 0 .30 - < 0.01 1.00E00 1.00E00 sensory perception of sour taste (GO:0050915) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of cobalamin metabolic process (GO:0106064) 1 0 .10 - < 0.01 1.00E00 1.00E00 detection of chemical stimulus involved in sensory perception of smell (GO:0050911) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of exit from mitosis (GO:0001100) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular polysaccharide catabolic process (GO:0044247) 10 0 .99 - < 0.01 1.00E00 1.00E00 positive regulation of gonadotropin secretion (GO:0032278) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of gonadotropin secretion (GO:0032277) 3 0 .30 - < 0.01 1.00E00 1.00E00 luteinizing hormone secretion (GO:0032275) 2 0 .20 - < 0.01 1.00E00 1.00E00 gonadotropin secretion (GO:0032274) 2 0 .20 - < 0.01 1.00E00 1.00E00 detection of light stimulus involved in visual perception (GO:0050908) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 leukocyte adhesive activation (GO:0050902) 2 0 .20 - < 0.01 1.00E00 1.00E00 GMP salvage (GO:0032263) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cellular response to osmotic stress (GO:0106049) 8 0 .79 - < 0.01 1.00E00 1.00E00 spermidine deacetylation (GO:0106048) 1 0 .10 - < 0.01 1.00E00 1.00E00 polyamine deacetylation (GO:0106047) 1 0 .10 - < 0.01 1.00E00 1.00E00 guanine deglycation, glyoxal removal (GO:0106046) 1 0 .10 - < 0.01 1.00E00 1.00E00 guanine deglycation, methylglyoxal removal (GO:0106045) 1 0 .10 - < 0.01 1.00E00 1.00E00 guanine deglycation (GO:0106044) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of GABA-A receptor activity (GO:0106040) 1 0 .10 - < 0.01 1.00E00 1.00E00 sperm flagellum assembly (GO:0120316) 19 0 1.88 - < 0.01 4.08E-01 1.00E00 establishment of secretory granule localization (GO:0032254) 1 0 .10 - < 0.01 1.00E00 1.00E00 dense core granule localization (GO:0032253) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of membrane depolarization during cardiac muscle cell action potential (GO:1900827) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of membrane depolarization during cardiac muscle cell action potential (GO:1900825) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein maturation by [4Fe-4S] cluster transfer (GO:0106035) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein maturation by [2Fe-2S] cluster transfer (GO:0106034) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of nucleoside transport (GO:0032244) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of nucleoside transport (GO:0032243) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of nucleoside transport (GO:0032242) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of nucleobase-containing compound transport (GO:0032241) 5 0 .49 - < 0.01 1.00E00 1.00E00 neuron projection retraction (GO:0106028) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of nucleobase-containing compound transport (GO:0032240) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of vesicle docking (GO:0106022) 1 0 .10 - < 0.01 1.00E00 1.00E00 AMP salvage (GO:0044209) 1 0 .10 - < 0.01 1.00E00 1.00E00 'de novo' AMP biosynthetic process (GO:0044208) 1 0 .10 - < 0.01 1.00E00 1.00E00 'de novo' UMP biosynthetic process (GO:0044205) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of nucleobase-containing compound transport (GO:0032239) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 positive regulation of inflammatory response to wounding (GO:0106016) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of synaptic transmission, dopaminergic (GO:0032227) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic transmission, dopaminergic (GO:0032226) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of synaptic transmission, dopaminergic (GO:0032225) 9 0 .89 - < 0.01 1.00E00 1.00E00 RNA 5'-cap (guanine-N7)-methylation (GO:0106005) 1 0 .10 - < 0.01 1.00E00 1.00E00 intestinal hexose absorption (GO:0106001) 3 0 .30 - < 0.01 1.00E00 1.00E00 riboflavin transport (GO:0032218) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of telomere maintenance via telomerase (GO:0032212) 30 0 2.97 - < 0.01 1.07E-01 8.99E-01 negative regulation of telomere maintenance via recombination (GO:0032208) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of telomere maintenance via recombination (GO:0032207) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of telomere maintenance (GO:0032206) 49 0 4.84 - < 0.01 2.05E-02 3.51E-01 telomere formation via telomerase (GO:0032203) 1 0 .10 - < 0.01 1.00E00 1.00E00 telomere assembly (GO:0032202) 4 0 .40 - < 0.01 1.00E00 1.00E00 telomere maintenance via semi-conservative replication (GO:0032201) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of polysome binding (GO:1905698) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of polysome binding (GO:1905696) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of phosphatidic acid biosynthetic process (GO:1905693) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of plasma membrane repair (GO:1905684) 3 0 .30 - < 0.01 1.00E00 1.00E00 inactivation of MAPKK activity (GO:0051389) 2 0 .20 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor transport, endosome to postsynaptic membrane (GO:0098887) 7 0 .69 - < 0.01 1.00E00 1.00E00 modification of dendritic spine (GO:0098886) 1 0 .10 - < 0.01 1.00E00 1.00E00 postsynaptic neurotransmitter receptor internalization (GO:0098884) 10 0 .99 - < 0.01 1.00E00 1.00E00 kinetochore organization (GO:0051383) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 kinetochore assembly (GO:0051382) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 maintenance of postsynaptic specialization structure (GO:0098880) 7 0 .69 - < 0.01 1.00E00 1.00E00 RNA localization to chromatin (GO:1990280) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of adaptive immune memory response (GO:1905676) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of adaptive immune memory response (GO:1905675) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of adaptive immune memory response (GO:1905674) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of lysosome organization (GO:1905673) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of lysosome organization (GO:1905672) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of lysosome organization (GO:1905671) 5 0 .49 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor transport to plasma membrane (GO:0098877) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 action potential propagation (GO:0098870) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to endosome (GO:1905667) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of telomerase RNA reverse transcriptase activity (GO:1905663) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of telomerase RNA reverse transcriptase activity (GO:1905662) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of telomerase RNA reverse transcriptase activity (GO:1905661) 3 0 .30 - < 0.01 1.00E00 1.00E00 intramembranous bone growth (GO:0098867) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to transition metal nanoparticle (GO:1990267) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to potassium ion starvation (GO:0051365) 2 0 .20 - < 0.01 1.00E00 1.00E00 peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity (GO:1990264) 8 0 .79 - < 0.01 1.00E00 1.00E00 anti-Mullerian hormone signaling pathway (GO:1990262) 1 0 .10 - < 0.01 1.00E00 1.00E00 pre-mRNA catabolic process (GO:1990261) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of artery morphogenesis (GO:1905652) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment (GO:1901297) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone glutamine methylation (GO:1990258) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment (GO:1901296) 1 0 .10 - < 0.01 1.00E00 1.00E00 proprioception involved in equilibrioception (GO:0051355) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment (GO:1901295) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of ligase activity (GO:0051351) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of double-strand break repair via single-strand annealing (GO:1901291) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of DNA methylation (GO:1905643) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of DNA methylation (GO:1905642) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of lyase activity (GO:0051349) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 regulation of transcription from RNA polymerase II promoter in response to DNA damage (GO:1990248) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cyclic-nucleotide phosphodiesterase activity (GO:0051344) 3 0 .30 - < 0.01 1.00E00 1.00E00 histone H2A-T120 phosphorylation (GO:1990245) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cyclic-nucleotide phosphodiesterase activity (GO:0051343) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of cyclic-nucleotide phosphodiesterase activity (GO:0051342) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of ligase activity (GO:0051340) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding (GO:1905636) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular response to glyceraldehyde (GO:1905631) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to glyceraldehyde (GO:1905630) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitotic interphase (GO:0051329) 2 0 .20 - < 0.01 1.00E00 1.00E00 modulation of inhibitory postsynaptic potential (GO:0098828) 8 0 .79 - < 0.01 1.00E00 1.00E00 paranodal junction maintenance (GO:1990227) 1 0 .10 - < 0.01 1.00E00 1.00E00 interphase (GO:0051325) 3 0 .30 - < 0.01 1.00E00 1.00E00 prophase (GO:0051324) 7 0 .69 - < 0.01 1.00E00 1.00E00 metaphase (GO:0051323) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of miRNA mediated inhibition of translation (GO:1905618) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of miRNA mediated inhibition of translation (GO:1905616) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of mRNA cap binding (GO:1905612) 1 0 .10 - < 0.01 1.00E00 1.00E00 G2 phase (GO:0051319) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of mRNA cap binding (GO:1905610) 1 0 .10 - < 0.01 1.00E00 1.00E00 G1 phase (GO:0051318) 1 0 .10 - < 0.01 1.00E00 1.00E00 evoked excitatory postsynaptic potential (GO:0098817) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of macrophage colony-stimulating factor production (GO:1901257) 1 0 .10 - < 0.01 1.00E00 1.00E00 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation (GO:0051316) 2 0 .20 - < 0.01 1.00E00 1.00E00 attachment of mitotic spindle microtubules to kinetochore (GO:0051315) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 spontaneous synaptic transmission (GO:0098814) 8 0 .79 - < 0.01 1.00E00 1.00E00 nucleotide-excision repair involved in interstrand cross-link repair (GO:1901255) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of intracellular transport of viral material (GO:1901254) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of intracellular transport of viral material (GO:1901253) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of intracellular transport of viral material (GO:1901252) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of lung goblet cell differentiation (GO:1901250) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of metanephric cap mesenchymal cell proliferation (GO:0090096) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of metanephric cap mesenchymal cell proliferation (GO:0090095) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of smooth muscle cell-matrix adhesion (GO:1905609) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of presynapse assembly (GO:1905607) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of extracellular matrix disassembly (GO:0090091) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of blood-brain barrier permeability (GO:1905604) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of receptor-mediated endocytosis involved in cholesterol transport (GO:1905602) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of receptor-mediated endocytosis involved in cholesterol transport (GO:1905601) 2 0 .20 - < 0.01 1.00E00 1.00E00 female meiosis chromosome separation (GO:0051309) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of lung goblet cell differentiation (GO:1901249) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of receptor-mediated endocytosis involved in cholesterol transport (GO:1905600) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of lung ciliated cell differentiation (GO:1901248) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitotic sister chromatid separation (GO:0051306) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of lung ciliated cell differentiation (GO:1901246) 1 0 .10 - < 0.01 1.00E00 1.00E00 chromosome movement towards spindle pole (GO:0051305) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of dipeptide transport (GO:0090089) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of oligopeptide transport (GO:0090088) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway (GO:0090082) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of heart induction by regulation of canonical Wnt signaling pathway (GO:0090081) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway (GO:0090080) 3 0 .30 - < 0.01 1.00E00 1.00E00 abscission (GO:0009838) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of convergent extension involved in axis elongation (GO:1901233) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of convergent extension involved in axis elongation (GO:1901232) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of non-canonical Wnt signaling pathway via JNK cascade (GO:1901231) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of protein homodimerization activity (GO:0090074) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of ribosome biogenesis (GO:0090071) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of non-canonical Wnt signaling pathway via JNK cascade (GO:1901229) 1 0 .10 - < 0.01 1.00E00 1.00E00 unidimensional cell growth (GO:0009826) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901228) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901227) 1 0 .10 - < 0.01 1.00E00 1.00E00 thrombin-activated receptor signaling pathway (GO:0070493) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of ribosome biogenesis (GO:0090069) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of thalamus size (GO:0090067) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of production of siRNA involved in RNA interference (GO:0090065) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of microtubule nucleation (GO:0090063) 6 0 .59 - < 0.01 1.00E00 1.00E00 T cell aggregation (GO:0070489) 2 0 .20 - < 0.01 1.00E00 1.00E00 detection of hypoxia (GO:0070483) 2 0 .20 - < 0.01 1.00E00 1.00E00 nuclear-transcribed mRNA catabolic process, non-stop decay (GO:0070481) 1 0 .10 - < 0.01 1.00E00 1.00E00 stilbene metabolic process (GO:0009810) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac chamber formation (GO:1901211) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cardiac chamber formation (GO:1901210) 1 0 .10 - < 0.01 1.00E00 1.00E00 post-embryonic camera-type eye morphogenesis (GO:0048597) 5 0 .49 - < 0.01 1.00E00 1.00E00 nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay (GO:0070478) 1 0 .10 - < 0.01 1.00E00 1.00E00 rRNA (guanine-N7)-methylation (GO:0070476) 2 0 .20 - < 0.01 1.00E00 1.00E00 rRNA base methylation (GO:0070475) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of heart looping (GO:1901208) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of uterine smooth muscle contraction (GO:0070474) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of heart looping (GO:1901207) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of uterine smooth muscle contraction (GO:0070473) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of uterine smooth muscle contraction (GO:0070472) 9 0 .89 - < 0.01 1.00E00 1.00E00 uterine smooth muscle contraction (GO:0070471) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of extracellular matrix assembly (GO:1901202) 1 0 .10 - < 0.01 1.00E00 1.00E00 determination of affect (GO:0050894) 1 0 .10 - < 0.01 1.00E00 1.00E00 sensory processing (GO:0050893) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of tubulin deacetylation (GO:0090044) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of tubulin deacetylation (GO:0090043) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 tubulin deacetylation (GO:0090042) 3 0 .30 - < 0.01 1.00E00 1.00E00 plus-end specific microtubule depolymerization (GO:0070462) 1 0 .10 - < 0.01 1.00E00 1.00E00 musculoskeletal movement, spinal reflex action (GO:0050883) 1 0 .10 - < 0.01 1.00E00 1.00E00 voluntary musculoskeletal movement (GO:0050882) 9 0 .89 - < 0.01 1.00E00 1.00E00 positive regulation of chaperone-mediated protein complex assembly (GO:0090035) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of chaperone-mediated protein complex assembly (GO:0090034) 1 0 .10 - < 0.01 1.00E00 1.00E00 notochord morphogenesis (GO:0048570) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of steroid hormone biosynthetic process (GO:0090032) 6 0 .59 - < 0.01 1.00E00 1.00E00 cellular detoxification of nitrogen compound (GO:0070458) 5 0 .49 - < 0.01 1.00E00 1.00E00 ectodermal digestive tract morphogenesis (GO:0048567) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of monocyte chemotaxis (GO:0090027) 5 0 .49 - < 0.01 1.00E00 1.00E00 post-embryonic animal organ morphogenesis (GO:0048563) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of neutrophil chemotaxis (GO:0090024) 3 0 .30 - < 0.01 1.00E00 1.00E00 establishment of anatomical structure orientation (GO:0048560) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of oligodendrocyte progenitor proliferation (GO:0070447) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of oligodendrocyte progenitor proliferation (GO:0070446) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of oligodendrocyte progenitor proliferation (GO:0070445) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of pinocytosis (GO:0048550) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway (GO:0070433) 3 0 .30 - < 0.01 1.00E00 1.00E00 primitive streak formation (GO:0090009) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway (GO:0070429) 1 0 .10 - < 0.01 1.00E00 1.00E00 nucleotide-binding oligomerization domain containing 1 signaling pathway (GO:0070427) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway (GO:0070425) 3 0 .30 - < 0.01 1.00E00 1.00E00 antibiotic metabolic process (GO:0016999) 2 0 .20 - < 0.01 1.00E00 1.00E00 progesterone receptor signaling pathway (GO:0050847) 9 0 .89 - < 0.01 1.00E00 1.00E00 bone marrow development (GO:0048539) 7 0 .69 - < 0.01 1.00E00 1.00E00 cellular response to cold (GO:0070417) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of heterochromatin organization (GO:0120263) 10 0 .99 - < 0.01 1.00E00 1.00E00 negative regulation of heterochromatin organization (GO:0120262) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of heterochromatin organization (GO:0120261) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 trehalose metabolism in response to stress (GO:0070413) 1 0 .10 - < 0.01 1.00E00 1.00E00 olefinic compound catabolic process (GO:0120256) 1 0 .10 - < 0.01 1.00E00 1.00E00 olefinic compound biosynthetic process (GO:0120255) 4 0 .40 - < 0.01 1.00E00 1.00E00 oxidation-dependent protein catabolic process (GO:0070407) 1 0 .10 - < 0.01 1.00E00 1.00E00 hydrocarbon catabolic process (GO:0120253) 3 0 .30 - < 0.01 1.00E00 1.00E00 hydrocarbon metabolic process (GO:0120252) 3 0 .30 - < 0.01 1.00E00 1.00E00 transposition, RNA-mediated (GO:0032197) 2 0 .20 - < 0.01 1.00E00 1.00E00 transposition (GO:0032196) 2 0 .20 - < 0.01 1.00E00 1.00E00 ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate (GO:0032194) 1 0 .10 - < 0.01 1.00E00 1.00E00 poly(A)+ mRNA export from nucleus (GO:0016973) 21 0 2.08 - < 0.01 2.52E-01 1.00E00 response to freezing (GO:0050826) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptide antigen stabilization (GO:0050823) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptide stabilization (GO:0050822) 1 0 .10 - < 0.01 1.00E00 1.00E00 septin cytoskeleton organization (GO:0032185) 3 0 .30 - < 0.01 1.00E00 1.00E00 doxorubicin transport (GO:1900753) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of formation of structure involved in a symbiotic process (GO:0044147) 1 0 .10 - < 0.01 1.00E00 1.00E00 modulation of formation of structure involved in a symbiotic process (GO:0044145) 1 0 .10 - < 0.01 1.00E00 1.00E00 glutathione deglycation (GO:0036531) 1 0 .10 - < 0.01 1.00E00 1.00E00 (R)-carnitine transport (GO:1900749) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of vascular endothelial growth factor signaling pathway (GO:1900748) 6 0 .59 - < 0.01 1.00E00 1.00E00 circadian sleep/wake cycle, sleep (GO:0050802) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway (GO:1900740) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein localization to motile cilium (GO:0120229) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein deglycation, glyoxal removal (GO:0036529) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-lysine deglycation (GO:0036528) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-arginine deglycation (GO:0036527) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-cysteine deglycation (GO:0036526) 1 0 .10 - < 0.01 1.00E00 1.00E00 larynx development (GO:0120224) 2 0 .20 - < 0.01 1.00E00 1.00E00 larynx morphogenesis (GO:0120223) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of blastocyst development (GO:0120222) 3 0 .30 - < 0.01 1.00E00 1.00E00 astrocyte-dopaminergic neuron signaling (GO:0036520) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway (GO:1900739) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway (GO:1900738) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway (GO:1900737) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of phospholipase C-activating G protein-coupled receptor signaling pathway (GO:1900736) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway (GO:1900731) 1 0 .10 - < 0.01 1.00E00 1.00E00 chemorepulsion of dopaminergic neuron axon (GO:0036518) 1 0 .10 - < 0.01 1.00E00 1.00E00 serotonergic neuron axon guidance (GO:0036515) 3 0 .30 - < 0.01 1.00E00 1.00E00 dopaminergic neuron axon guidance (GO:0036514) 4 0 .40 - < 0.01 1.00E00 1.00E00 trimming of terminal mannose on C branch (GO:0036510) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway (GO:1900729) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of uterine smooth muscle relaxation (GO:1900721) 1 0 .10 - < 0.01 1.00E00 1.00E00 trimming of terminal mannose on B branch (GO:0036509) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein alpha-1,2-demannosylation (GO:0036508) 5 0 .49 - < 0.01 1.00E00 1.00E00 protein demannosylation (GO:0036507) 5 0 .49 - < 0.01 1.00E00 1.00E00 maintenance of unfolded protein (GO:0036506) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein desumoylation (GO:0016926) 9 0 .89 - < 0.01 1.00E00 1.00E00 regulation of uterine smooth muscle relaxation (GO:1900719) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular alcohol biosynthetic process (GO:0044108) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular alcohol metabolic process (GO:0044107) 3 0 .30 - < 0.01 1.00E00 1.00E00 sequestering of zinc ion (GO:0032119) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of carbohydrate phosphatase activity (GO:0032113) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of response to nutrient levels (GO:0032109) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of response to extracellular stimulus (GO:0032106) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of appetite (GO:0032100) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell dedifferentiation (GO:0043697) 3 0 .30 - < 0.01 1.00E00 1.00E00 dedifferentiation (GO:0043696) 3 0 .30 - < 0.01 1.00E00 1.00E00 reverse cholesterol transport (GO:0043691) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 negative regulation of low-density lipoprotein receptor activity (GO:1905598) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of low-density lipoprotein particle receptor binding (GO:1905597) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of low-density lipoprotein particle receptor binding (GO:1905596) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of low-density lipoprotein particle receptor binding (GO:1905595) 2 0 .20 - < 0.01 1.00E00 1.00E00 centrosome separation (GO:0051299) 6 0 .59 - < 0.01 1.00E00 1.00E00 fibronectin fibril organization (GO:1905590) 1 0 .10 - < 0.01 1.00E00 1.00E00 centrosome duplication (GO:0051298) 34 0 3.36 - < 0.01 6.96E-02 7.21E-01 mRNA cleavage involved in gene silencing (GO:0098795) 2 0 .20 - < 0.01 1.00E00 1.00E00 co-translational protein modification (GO:0043686) 3 0 .30 - < 0.01 1.00E00 1.00E00 xenophagy (GO:0098792) 4 0 .40 - < 0.01 1.00E00 1.00E00 nuclear pore complex assembly (GO:0051292) 9 0 .89 - < 0.01 1.00E00 1.00E00 protein heterotetramerization (GO:0051290) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 induction of programmed cell death (GO:0012502) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of L-arginine import across plasma membrane (GO:1905589) 1 0 .10 - < 0.01 1.00E00 1.00E00 outer hair cell apoptotic process (GO:1905584) 1 0 .10 - < 0.01 1.00E00 1.00E00 pre-mRNA cleavage required for polyadenylation (GO:0098789) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 positive regulation of low-density lipoprotein particle clearance (GO:1905581) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of ERBB3 signaling pathway (GO:1905580) 1 0 .10 - < 0.01 1.00E00 1.00E00 ncRNA transcription (GO:0098781) 28 0 2.77 - < 0.01 1.73E-01 9.70E-01 mitochondrial tRNA 3'-end processing (GO:1990180) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of ERBB3 signaling pathway (GO:1905578) 1 0 .10 - < 0.01 1.00E00 1.00E00 ganglioside GM1 transport to membrane (GO:1905572) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of mitophagy in response to mitochondrial depolarization (GO:0098779) 8 0 .79 - < 0.01 1.00E00 1.00E00 protein localization to nucleoplasm (GO:1990173) 3 0 .30 - < 0.01 1.00E00 1.00E00 G protein-coupled receptor catabolic process (GO:1990172) 1 0 .10 - < 0.01 1.00E00 1.00E00 meiotic prometaphase I (GO:0098768) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein K33-linked deubiquitination (GO:1990168) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein K27-linked deubiquitination (GO:1990167) 3 0 .30 - < 0.01 1.00E00 1.00E00 meiosis I cell cycle phase (GO:0098764) 8 0 .79 - < 0.01 1.00E00 1.00E00 protein localization to site of double-strand break (GO:1990166) 5 0 .49 - < 0.01 1.00E00 1.00E00 mitotic cell cycle phase (GO:0098763) 4 0 .40 - < 0.01 1.00E00 1.00E00 meiotic cell cycle phase (GO:0098762) 8 0 .79 - < 0.01 1.00E00 1.00E00 mitochondrial fragmentation involved in apoptotic process (GO:0043653) 9 0 .89 - < 0.01 1.00E00 1.00E00 dicarboxylic acid biosynthetic process (GO:0043650) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 positive regulation of blood vessel branching (GO:1905555) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of blood vessel branching (GO:1905553) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to endoplasmic reticulum (GO:1905552) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of protein localization to endoplasmic reticulum (GO:1905550) 2 0 .20 - < 0.01 1.00E00 1.00E00 meiotic spindle midzone assembly (GO:0051257) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitotic spindle midzone assembly (GO:0051256) 6 0 .59 - < 0.01 1.00E00 1.00E00 spindle midzone assembly (GO:0051255) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of formation of translation preinitiation complex (GO:1901194) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of formation of translation preinitiation complex (GO:1901193) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of subtelomeric heterochromatin assembly (GO:1905549) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of subtelomeric heterochromatin assembly (GO:1905547) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of abscisic acid-activated signaling pathway (GO:0009789) 1 0 .10 - < 0.01 1.00E00 1.00E00 cerebellar neuron development (GO:0098749) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of L-arginine import across plasma membrane (GO:1905541) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of abscisic acid-activated signaling pathway (GO:0009787) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of asymmetric cell division (GO:0009786) 4 0 .40 - < 0.01 1.00E00 1.00E00 maintenance of translational fidelity (GO:1990145) 2 0 .20 - < 0.01 1.00E00 1.00E00 polyadenylation-dependent ncRNA catabolic process (GO:0043634) 7 0 .69 - < 0.01 1.00E00 1.00E00 intrinsic apoptotic signaling pathway in response to hypoxia (GO:1990144) 2 0 .20 - < 0.01 1.00E00 1.00E00 polyadenylation-dependent RNA catabolic process (GO:0043633) 8 0 .79 - < 0.01 1.00E00 1.00E00 ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process (GO:0043630) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of eukaryotic translation initiation factor 4F complex assembly (GO:1905537) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of eukaryotic translation initiation factor 4F complex assembly (GO:1905535) 1 0 .10 - < 0.01 1.00E00 1.00E00 ncRNA polyadenylation (GO:0043629) 1 0 .10 - < 0.01 1.00E00 1.00E00 ncRNA 3'-end processing (GO:0043628) 38 0 3.76 - < 0.01 4.56E-02 5.69E-01 negative regulation of the force of heart contraction (GO:0098736) 1 0 .10 - < 0.01 1.00E00 1.00E00 macromolecule depalmitoylation (GO:0098734) 10 0 .99 - < 0.01 1.00E00 1.00E00 epithelial cell apoptotic process involved in palatal shelf morphogenesis (GO:1990134) 1 0 .10 - < 0.01 1.00E00 1.00E00 meiotic spindle elongation (GO:0051232) 1 0 .10 - < 0.01 1.00E00 1.00E00 cortical microtubule organization (GO:0043622) 4 0 .40 - < 0.01 1.00E00 1.00E00 spindle elongation (GO:0051231) 7 0 .69 - < 0.01 1.00E00 1.00E00 spindle disassembly (GO:0051230) 2 0 .20 - < 0.01 1.00E00 1.00E00 naphthalene catabolic process (GO:1901170) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of heat generation (GO:0031651) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of Golgi lumen acidification (GO:1905528) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of Golgi lumen acidification (GO:1905526) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of protein autoubiquitination (GO:1905524) 2 0 .20 - < 0.01 1.00E00 1.00E00 germline stem cell asymmetric division (GO:0098728) 4 0 .40 - < 0.01 1.00E00 1.00E00 mitotic spindle disassembly (GO:0051228) 2 0 .20 - < 0.01 1.00E00 1.00E00 keratinocyte proliferation (GO:0043616) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of trophoblast cell migration (GO:1901165) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of trophoblast cell migration (GO:1901164) 4 0 .40 - < 0.01 1.00E00 1.00E00 asymmetric stem cell division (GO:0098722) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of trophoblast cell migration (GO:1901163) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 primary amino compound biosynthetic process (GO:1901162) 3 0 .30 - < 0.01 1.00E00 1.00E00 primary amino compound metabolic process (GO:1901160) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 regulation of carbohydrate utilization (GO:0043610) 1 0 .10 - < 0.01 1.00E00 1.00E00 messenger ribonucleoprotein complex assembly (GO:1990120) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of myelination (GO:0031642) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 positive regulation of fertilization (GO:1905516) 4 0 .40 - < 0.01 1.00E00 1.00E00 carbohydrate utilization (GO:0009758) 1 0 .10 - < 0.01 1.00E00 1.00E00 sodium ion import across plasma membrane (GO:0098719) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 hexose mediated signaling (GO:0009757) 2 0 .20 - < 0.01 1.00E00 1.00E00 serine import across plasma membrane (GO:0098718) 1 0 .10 - < 0.01 1.00E00 1.00E00 carbohydrate mediated signaling (GO:0009756) 2 0 .20 - < 0.01 1.00E00 1.00E00 B cell receptor apoptotic signaling pathway (GO:1990117) 1 0 .10 - < 0.01 1.00E00 1.00E00 formamide metabolic process (GO:0043606) 1 0 .10 - < 0.01 1.00E00 1.00E00 ribosome-associated ubiquitin-dependent protein catabolic process (GO:1990116) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular amide catabolic process (GO:0043605) 1 0 .10 - < 0.01 1.00E00 1.00E00 RNA polymerase II core complex assembly (GO:1990114) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to fructose (GO:0009750) 3 0 .30 - < 0.01 1.00E00 1.00E00 iron ion import across plasma membrane (GO:0098711) 2 0 .20 - < 0.01 1.00E00 1.00E00 nitrate catabolic process (GO:0043602) 1 0 .10 - < 0.01 1.00E00 1.00E00 plasminogen activation (GO:0031639) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic vesicle fusion to presynaptic active zone membrane (GO:0031632) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of synaptic vesicle fusion to presynaptic active zone membrane (GO:0031630) 8 0 .79 - < 0.01 1.00E00 1.00E00 protein localization to microtubule organizing center (GO:1905508) 25 0 2.47 - < 0.01 1.63E-01 1.00E00 positive regulation of motile cilium assembly (GO:1905505) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of motile cilium assembly (GO:1905503) 1 0 .10 - < 0.01 1.00E00 1.00E00 glucose import across plasma membrane (GO:0098708) 4 0 .40 - < 0.01 1.00E00 1.00E00 gene expression involved in extracellular matrix organization (GO:1901148) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein linear deubiquitination (GO:1990108) 3 0 .30 - < 0.01 1.00E00 1.00E00 copper ion import across plasma membrane (GO:0098705) 2 0 .20 - < 0.01 1.00E00 1.00E00 carbohydrate import across plasma membrane (GO:0098704) 4 0 .40 - < 0.01 1.00E00 1.00E00 neurotransmitter loading into synaptic vesicle (GO:0098700) 5 0 .49 - < 0.01 1.00E00 1.00E00 telomeric loop formation (GO:0031627) 2 0 .20 - < 0.01 1.00E00 1.00E00 homologous chromosome orientation involved in meiotic metaphase I plate congression (GO:0031619) 1 0 .10 - < 0.01 1.00E00 1.00E00 detection of lipoteichoic acid (GO:0070392) 1 0 .10 - < 0.01 1.00E00 1.00E00 tRNA-guanine transglycosylation (GO:0101030) 3 0 .30 - < 0.01 1.00E00 1.00E00 mitotic nuclear membrane organization (GO:0101024) 3 0 .30 - < 0.01 1.00E00 1.00E00 Harderian gland development (GO:0070384) 4 0 .40 - < 0.01 1.00E00 1.00E00 DNA cytosine deamination (GO:0070383) 3 0 .30 - < 0.01 1.00E00 1.00E00 maintenance of animal organ identity (GO:0048496) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of ERK5 cascade (GO:0070378) 1 0 .10 - < 0.01 1.00E00 1.00E00 ERK5 cascade (GO:0070375) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular heat acclimation (GO:0070370) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of hepatocyte differentiation (GO:0070368) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of hepatocyte differentiation (GO:0070366) 3 0 .30 - < 0.01 1.00E00 1.00E00 detoxification of mercury ion (GO:0050787) 2 0 .20 - < 0.01 1.00E00 1.00E00 replication fork protection (GO:0048478) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of white fat cell proliferation (GO:0070352) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of white fat cell proliferation (GO:0070351) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of white fat cell proliferation (GO:0070350) 3 0 .30 - < 0.01 1.00E00 1.00E00 PERK-mediated unfolded protein response (GO:0036499) 6 0 .59 - < 0.01 1.00E00 1.00E00 mucociliary clearance (GO:0120197) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of translational initiation by eIF2 alpha dephosphorylation (GO:0036496) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of brown fat cell proliferation (GO:0070348) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of translation initiation in response to endoplasmic reticulum stress (GO:0036494) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of brown fat cell proliferation (GO:0070347) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of translation in response to endoplasmic reticulum stress (GO:0036493) 5 0 .49 - < 0.01 1.00E00 1.00E00 eiF2alpha phosphorylation in response to endoplasmic reticulum stress (GO:0036492) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of fat cell proliferation (GO:0070345) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of termination of RNA polymerase II transcription (GO:0120191) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of translation initiation in response to endoplasmic reticulum stress (GO:0036491) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of bile acid secretion (GO:0120190) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of translation in response to endoplasmic reticulum stress (GO:0036490) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of bile acid secretion (GO:0120188) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to chromatin (GO:0120187) 1 0 .10 - < 0.01 1.00E00 1.00E00 focal adhesion disassembly (GO:0120181) 1 0 .10 - < 0.01 1.00E00 1.00E00 intrinsic apoptotic signaling pathway in response to hydrogen peroxide (GO:0036481) 2 0 .20 - < 0.01 1.00E00 1.00E00 cell-substrate junction disassembly (GO:0120180) 1 0 .10 - < 0.01 1.00E00 1.00E00 steroid hormone biosynthetic process (GO:0120178) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 neuron death in response to oxidative stress (GO:0036475) 3 0 .30 - < 0.01 1.00E00 1.00E00 cell death in response to hydrogen peroxide (GO:0036474) 3 0 .30 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by BDNF (GO:0099191) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to glyoxal (GO:0036471) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of lipoprotein metabolic process (GO:0050748) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of lipoprotein metabolic process (GO:0050747) 5 0 .49 - < 0.01 1.00E00 1.00E00 presynaptic cytoskeleton organization (GO:0099187) 1 0 .10 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by BDNF, modulating synaptic transmission (GO:0099183) 2 0 .20 - < 0.01 1.00E00 1.00E00 zinc ion import into synaptic vesicle (GO:0099180) 1 0 .10 - < 0.01 1.00E00 1.00E00 G1 to G0 transition involved in cell differentiation (GO:0070315) 3 0 .30 - < 0.01 1.00E00 1.00E00 G1 to G0 transition (GO:0070314) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of synaptic membrane adhesion (GO:0099179) 4 0 .40 - < 0.01 1.00E00 1.00E00 lens fiber cell morphogenesis (GO:0070309) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of ERBB4 signaling pathway (GO:0120154) 1 0 .10 - < 0.01 1.00E00 1.00E00 postsynaptic modulation of chemical synaptic transmission (GO:0099170) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 response to cGMP (GO:0070305) 4 0 .40 - < 0.01 1.00E00 1.00E00 cap mRNA methylation (GO:0036451) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of response to food (GO:0032097) 1 0 .10 - < 0.01 1.00E00 1.00E00 synaptic signaling by nitric oxide (GO:0099163) 3 0 .30 - < 0.01 1.00E00 1.00E00 neuronal stem cell division (GO:0036445) 1 0 .10 - < 0.01 1.00E00 1.00E00 translocation of peptides or proteins into host cell cytoplasm (GO:0044053) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of presynaptic dense core granule exocytosis (GO:0099161) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of recycling endosome localization within postsynapse (GO:0099158) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell-cell signaling via exosome (GO:0099156) 1 0 .10 - < 0.01 1.00E00 1.00E00 synaptic transmission, serotonergic (GO:0099153) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane (GO:0099152) 2 0 .20 - < 0.01 1.00E00 1.00E00 multi-organism carbohydrate catabolic process (GO:0044041) 1 0 .10 - < 0.01 1.00E00 1.00E00 multi-organism carbohydrate metabolic process (GO:0044040) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of endodeoxyribonuclease activity (GO:0032079) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of endodeoxyribonuclease activity (GO:0032078) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of deoxyribonuclease activity (GO:0032077) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of deoxyribonuclease activity (GO:0032076) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of nuclease activity (GO:0032075) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of nuclease activity (GO:0032074) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of endodeoxyribonuclease activity (GO:0032071) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of deoxyribonuclease activity (GO:0032070) 9 0 .89 - < 0.01 1.00E00 1.00E00 cell wall macromolecule biosynthetic process (GO:0044038) 1 0 .10 - < 0.01 1.00E00 1.00E00 multi-organism cell wall macromolecule metabolic process (GO:0044037) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to zinc ion starvation (GO:0120127) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell wall macromolecule metabolic process (GO:0044036) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to copper ion starvation (GO:0120126) 1 0 .10 - < 0.01 1.00E00 1.00E00 multi-organism catabolic process (GO:0044035) 2 0 .20 - < 0.01 1.00E00 1.00E00 multi-organism metabolic process (GO:0044033) 2 0 .20 - < 0.01 1.00E00 1.00E00 presynaptic actin cytoskeleton organization (GO:0099140) 1 0 .10 - < 0.01 1.00E00 1.00E00 bleb assembly (GO:0032060) 10 0 .99 - < 0.01 1.00E00 1.00E00 hypomethylation of CpG island (GO:0044029) 2 0 .20 - < 0.01 1.00E00 1.00E00 DNA hypomethylation (GO:0044028) 2 0 .20 - < 0.01 1.00E00 1.00E00 tRNA stabilization (GO:0036416) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of tRNA stability (GO:0036415) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of translational initiation in response to stress (GO:0032058) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of translational initiation in response to stress (GO:0032057) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of translation in response to stress (GO:0032056) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of translation in response to stress (GO:0032055) 6 0 .59 - < 0.01 1.00E00 1.00E00 ciliary basal body organization (GO:0032053) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of monocyte aggregation (GO:1900625) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of monocyte aggregation (GO:1900623) 3 0 .30 - < 0.01 1.00E00 1.00E00 acetate ester biosynthetic process (GO:1900620) 1 0 .10 - < 0.01 1.00E00 1.00E00 conversion of ds siRNA to ss siRNA (GO:0036404) 1 0 .10 - < 0.01 1.00E00 1.00E00 cardiolipin biosynthetic process (GO:0032049) 8 0 .79 - < 0.01 1.00E00 1.00E00 cardiolipin metabolic process (GO:0032048) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 mitochondrial DNA metabolic process (GO:0032042) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 box H/ACA RNA 3'-end processing (GO:0000495) 2 0 .20 - < 0.01 1.00E00 1.00E00 box C/D RNA 3'-end processing (GO:0000494) 3 0 .30 - < 0.01 1.00E00 1.00E00 box H/ACA snoRNP assembly (GO:0000493) 2 0 .20 - < 0.01 1.00E00 1.00E00 box C/D snoRNP assembly (GO:0000492) 10 0 .99 - < 0.01 1.00E00 1.00E00 small nucleolar ribonucleoprotein complex assembly (GO:0000491) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 maturation of 5S rRNA (GO:0000481) 1 0 .10 - < 0.01 1.00E00 1.00E00 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000480) 6 0 .59 - < 0.01 1.00E00 1.00E00 response to cobalt ion (GO:0032025) 3 0 .30 - < 0.01 1.00E00 1.00E00 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000479) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 endonucleolytic cleavage involved in rRNA processing (GO:0000478) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000472) 3 0 .30 - < 0.01 1.00E00 1.00E00 maturation of LSU-rRNA (GO:0000470) 29 0 2.87 - < 0.01 1.06E-01 8.96E-01 positive regulation of ARF protein signal transduction (GO:0032014) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of ARF protein signal transduction (GO:0032013) 1 0 .10 - < 0.01 1.00E00 1.00E00 ARF protein signal transduction (GO:0032011) 1 0 .10 - < 0.01 1.00E00 1.00E00 cleavage involved in rRNA processing (GO:0000469) 27 0 2.67 - < 0.01 1.68E-01 1.00E00 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000467) 9 0 .89 - < 0.01 1.00E00 1.00E00 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000466) 24 0 2.37 - < 0.01 1.63E-01 1.00E00 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000463) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000462) 35 0 3.46 - < 0.01 7.06E-02 7.30E-01 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000461) 1 0 .10 - < 0.01 1.00E00 1.00E00 maturation of 5.8S rRNA (GO:0000460) 35 0 3.46 - < 0.01 7.06E-02 7.29E-01 tetrahydrofolate interconversion (GO:0035999) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 deltoid tuberosity development (GO:0035993) 3 0 .30 - < 0.01 1.00E00 1.00E00 tendon formation (GO:0035992) 3 0 .30 - < 0.01 1.00E00 1.00E00 tendon cell differentiation (GO:0035990) 3 0 .30 - < 0.01 1.00E00 1.00E00 exonucleolytic trimming involved in rRNA processing (GO:0000459) 9 0 .89 - < 0.01 1.00E00 1.00E00 enzyme-directed rRNA pseudouridine synthesis (GO:0000455) 6 0 .59 - < 0.01 1.00E00 1.00E00 rRNA 2'-O-methylation (GO:0000451) 1 0 .10 - < 0.01 1.00E00 1.00E00 chondrocyte proliferation (GO:0035988) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 cellular response to trichostatin A (GO:0035984) 3 0 .30 - < 0.01 1.00E00 1.00E00 response to trichostatin A (GO:0035983) 3 0 .30 - < 0.01 1.00E00 1.00E00 endocytic hemoglobin import into cell (GO:0020028) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to host (GO:0075136) 1 0 .10 - < 0.01 1.00E00 1.00E00 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000448) 3 0 .30 - < 0.01 1.00E00 1.00E00 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000447) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of branching morphogenesis of a nerve (GO:1905492) 2 0 .20 - < 0.01 1.00E00 1.00E00 skin morphogenesis (GO:0043589) 10 0 .99 - < 0.01 1.00E00 1.00E00 tongue morphogenesis (GO:0043587) 10 0 .99 - < 0.01 1.00E00 1.00E00 protein deglycosylation involved in glycoprotein catabolic process (GO:0035977) 5 0 .49 - < 0.01 1.00E00 1.00E00 nose morphogenesis (GO:0043585) 1 0 .10 - < 0.01 1.00E00 1.00E00 nose development (GO:0043584) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 aggrephagy (GO:0035973) 5 0 .49 - < 0.01 1.00E00 1.00E00 calcium-dependent self proteolysis (GO:1990092) 2 0 .20 - < 0.01 1.00E00 1.00E00 sodium-dependent self proteolysis (GO:1990091) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-histidine dephosphorylation (GO:0035971) 1 0 .10 - < 0.01 1.00E00 1.00E00 carbon catabolite activation of transcription from RNA polymerase II promoter (GO:0000436) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of transcription from RNA polymerase II promoter by galactose (GO:0000435) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of transcription from RNA polymerase II promoter by glucose (GO:0000432) 2 0 .20 - < 0.01 1.00E00 1.00E00 prosthetic group metabolic process (GO:0051189) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of transcription from RNA polymerase II promoter by galactose (GO:0000431) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of transcription from RNA polymerase II promoter by glucose (GO:0000430) 2 0 .20 - < 0.01 1.00E00 1.00E00 cardiolipin acyl-chain remodeling (GO:0035965) 4 0 .40 - < 0.01 1.00E00 1.00E00 COPI-coated vesicle budding (GO:0035964) 5 0 .49 - < 0.01 1.00E00 1.00E00 maintenance of DNA repeat elements (GO:0043570) 7 0 .69 - < 0.01 1.00E00 1.00E00 carbon catabolite regulation of transcription from RNA polymerase II promoter (GO:0000429) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of insulin-like growth factor receptor signaling pathway (GO:0043569) 9 0 .89 - < 0.01 1.00E00 1.00E00 cartilage homeostasis (GO:1990079) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of sulfur metabolic process (GO:0051176) 5 0 .49 - < 0.01 1.00E00 1.00E00 polyuridylation-dependent mRNA catabolic process (GO:1990074) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to nitrogen levels (GO:0043562) 9 0 .89 - < 0.01 1.00E00 1.00E00 wybutosine biosynthetic process (GO:0031591) 3 0 .30 - < 0.01 1.00E00 1.00E00 wybutosine metabolic process (GO:0031590) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of clathrin-coated pit assembly (GO:1905469) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of clathrin-coated pit assembly (GO:1905468) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of histone H3-K36 methylation (GO:0000416) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of DNA duplex unwinding (GO:1905464) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of histone H3-K36 methylation (GO:0000415) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of DNA duplex unwinding (GO:1905463) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of histone H3-K36 methylation (GO:0000414) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of DNA duplex unwinding (GO:1905462) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of transcription by galactose (GO:0000411) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of translational initiation in response to stress (GO:0043558) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of translation in response to oxidative stress (GO:0043556) 1 0 .10 - < 0.01 1.00E00 1.00E00 G protein-coupled serotonin receptor signaling pathway (GO:0098664) 6 0 .59 - < 0.01 1.00E00 1.00E00 mitochondrial mRNA surveillance (GO:0035946) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of translation in response to stress (GO:0043555) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 mitochondrial ncRNA surveillance (GO:0035945) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (GO:0031587) 4 0 .40 - < 0.01 1.00E00 1.00E00 activation of phospholipase D activity (GO:0031584) 6 0 .59 - < 0.01 1.00E00 1.00E00 phospholipase D-activating G protein-coupled receptor signaling pathway (GO:0031583) 2 0 .20 - < 0.01 1.00E00 1.00E00 membrane raft distribution (GO:0031580) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of lymphoid progenitor cell differentiation (GO:1905458) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of transcription by galactose (GO:0000409) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of myeloid progenitor cell differentiation (GO:1905454) 1 0 .10 - < 0.01 1.00E00 1.00E00 inorganic anion import across plasma membrane (GO:0098658) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis (GO:1905450) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of autophagosome maturation (GO:1901097) 5 0 .49 - < 0.01 1.00E00 1.00E00 molybdopterin cofactor metabolic process (GO:0043545) 6 0 .59 - < 0.01 1.00E00 1.00E00 corticosterone secretion (GO:0035934) 1 0 .10 - < 0.01 1.00E00 1.00E00 glucocorticoid secretion (GO:0035933) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of smooth muscle cell differentiation (GO:0051151) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 corticosteroid hormone secretion (GO:0035930) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitotic G1 DNA damage checkpoint signaling (GO:0031571) 21 0 2.08 - < 0.01 2.52E-01 1.00E00 positive regulation of mitochondrial ATP synthesis coupled electron transport (GO:1905448) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial ATP synthesis coupled electron transport (GO:1905447) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial ATP synthesis coupled electron transport (GO:1905446) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of clathrin coat assembly (GO:1905445) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of clathrin coat assembly (GO:1905443) 2 0 .20 - < 0.01 1.00E00 1.00E00 retrograde neuronal dense core vesicle transport (GO:1990049) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of actin phosphorylation (GO:0043538) 1 0 .10 - < 0.01 1.00E00 1.00E00 anterograde neuronal dense core vesicle transport (GO:1990048) 2 0 .20 - < 0.01 1.00E00 1.00E00 benzylpenicillin metabolic process (GO:1901086) 1 0 .10 - < 0.01 1.00E00 1.00E00 stress-induced mitochondrial fusion (GO:1990046) 2 0 .20 - < 0.01 1.00E00 1.00E00 induced systemic resistance (GO:0009682) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to lipid droplet (GO:1990044) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of relaxation of smooth muscle (GO:1901082) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of NK T cell proliferation (GO:0051141) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of relaxation of smooth muscle (GO:1901081) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of relaxation of smooth muscle (GO:1901080) 3 0 .30 - < 0.01 1.00E00 1.00E00 desmosome disassembly (GO:0035921) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of histone H3-K4 trimethylation (GO:1905437) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of histone H3-K4 trimethylation (GO:1905435) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of retrograde trans-synaptic signaling by neuropeptide (GO:1905433) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of retrograde trans-synaptic signaling by neuropeptide (GO:1905432) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of relaxation of muscle (GO:1901079) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular response to glycine (GO:1905430) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of NK T cell differentiation (GO:0051138) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of NK T cell differentiation (GO:0051136) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of engulfment of apoptotic cell (GO:1901076) 2 0 .20 - < 0.01 1.00E00 1.00E00 calcium ion import into sarcoplasmic reticulum (GO:1990036) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of NK T cell activation (GO:0051134) 2 0 .20 - < 0.01 1.00E00 1.00E00 glucosamine-containing compound biosynthetic process (GO:1901073) 1 0 .10 - < 0.01 1.00E00 1.00E00 calcium ion export across plasma membrane (GO:1990034) 4 0 .40 - < 0.01 1.00E00 1.00E00 NK T cell activation (GO:0051132) 2 0 .20 - < 0.01 1.00E00 1.00E00 dorsal aorta morphogenesis (GO:0035912) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of DNA-templated transcription, termination (GO:0031554) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of brain-derived neurotrophic factor-activated receptor activity (GO:0031552) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of brain-derived neurotrophic factor-activated receptor activity (GO:0031551) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to glycine (GO:1905429) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation (GO:1905426) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of Wnt-mediated midbrain dopaminergic neuron differentiation (GO:1905424) 1 0 .10 - < 0.01 1.00E00 1.00E00 trans-Golgi network membrane organization (GO:0098629) 2 0 .20 - < 0.01 1.00E00 1.00E00 guanosine-containing compound catabolic process (GO:1901069) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of myosin II filament organization (GO:0043519) 2 0 .20 - < 0.01 1.00E00 1.00E00 guanosine-containing compound metabolic process (GO:1901068) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 dorsal aorta development (GO:0035907) 9 0 .89 - < 0.01 1.00E00 1.00E00 descending aorta development (GO:0035906) 1 0 .10 - < 0.01 1.00E00 1.00E00 RNA polymerase II preinitiation complex assembly (GO:0051123) 9 0 .89 - < 0.01 1.00E00 1.00E00 response to immobilization stress (GO:0035902) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of brain-derived neurotrophic factor receptor signaling pathway (GO:0031549) 2 0 .20 - < 0.01 1.00E00 1.00E00 brain-derived neurotrophic factor receptor signaling pathway (GO:0031547) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of dense core granule exocytosis (GO:1905415) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of dense core granule exocytosis (GO:1905414) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of dense core granule exocytosis (GO:1905413) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of JUN kinase activity (GO:0043508) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 mitochondrial DNA repair (GO:0043504) 6 0 .59 - < 0.01 1.00E00 1.00E00 sarcosine catabolic process (GO:1901053) 1 0 .10 - < 0.01 1.00E00 1.00E00 UV protection (GO:0009650) 9 0 .89 - < 0.01 1.00E00 1.00E00 sarcosine metabolic process (GO:1901052) 1 0 .10 - < 0.01 1.00E00 1.00E00 skeletal muscle adaptation (GO:0043501) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of creatine transmembrane transporter activity (GO:1905408) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of creatine transmembrane transporter activity (GO:1905407) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic cohesin loading (GO:1905406) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mitotic cohesin loading (GO:1905405) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process (GO:1905404) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process (GO:1905403) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of activated CD8-positive, alpha-beta T cell apoptotic process (GO:1905402) 3 0 .30 - < 0.01 1.00E00 1.00E00 retinal cell apoptotic process (GO:1990009) 3 0 .30 - < 0.01 1.00E00 1.00E00 response to high light intensity (GO:0009644) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of DNA ligation (GO:0051106) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of DNA ligation (GO:0051105) 4 0 .40 - < 0.01 1.00E00 1.00E00 response to light intensity (GO:0009642) 6 0 .59 - < 0.01 1.00E00 1.00E00 DNA ligation involved in DNA repair (GO:0051103) 4 0 .40 - < 0.01 1.00E00 1.00E00 DNA ligation involved in DNA recombination (GO:0051102) 1 0 .10 - < 0.01 1.00E00 1.00E00 inhibition of cysteine-type endopeptidase activity involved in apoptotic process (GO:1990001) 4 0 .40 - < 0.01 1.00E00 1.00E00 response to red or far red light (GO:0009639) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to blue light (GO:0009637) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of response to reactive oxygen species (GO:1901033) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway (GO:1901030) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 response to gravity (GO:0009629) 1 0 .10 - < 0.01 1.00E00 1.00E00 sarcoplasmic reticulum calcium ion transport (GO:0070296) 8 0 .79 - < 0.01 1.00E00 1.00E00 ripoptosome assembly involved in necroptotic process (GO:1901026) 2 0 .20 - < 0.01 1.00E00 1.00E00 N-acylphosphatidylethanolamine metabolic process (GO:0070292) 3 0 .30 - < 0.01 1.00E00 1.00E00 N-acylethanolamine metabolic process (GO:0070291) 6 0 .59 - < 0.01 1.00E00 1.00E00 cell wall glycoprotein biosynthetic process (GO:0031506) 1 0 .10 - < 0.01 1.00E00 1.00E00 axonemal dynein complex assembly (GO:0070286) 24 0 2.37 - < 0.01 1.63E-01 1.00E00 intermediate mesodermal cell differentiation (GO:0048392) 1 0 .10 - < 0.01 1.00E00 1.00E00 intermediate mesoderm formation (GO:0048391) 1 0 .10 - < 0.01 1.00E00 1.00E00 intermediate mesoderm morphogenesis (GO:0048390) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to symbiotic bacterium (GO:0009609) 2 0 .20 - < 0.01 1.00E00 1.00E00 extracellular matrix constituent secretion (GO:0070278) 4 0 .40 - < 0.01 1.00E00 1.00E00 response to symbiont (GO:0009608) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of leukocyte adhesion to arterial endothelial cell (GO:1904999) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of leukocyte adhesion to arterial endothelial cell (GO:1904998) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of leukocyte adhesion to arterial endothelial cell (GO:1904997) 4 0 .40 - < 0.01 1.00E00 1.00E00 ubiquinone-6 biosynthetic process (GO:1901006) 1 0 .10 - < 0.01 1.00E00 1.00E00 ubiquinone-6 metabolic process (GO:1901004) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of fermentation (GO:1901003) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway (GO:1904992) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway (GO:1904990) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of response to salt stress (GO:1901000) 4 0 .40 - < 0.01 1.00E00 1.00E00 intermediate mesoderm development (GO:0048389) 1 0 .10 - < 0.01 1.00E00 1.00E00 endosomal lumen acidification (GO:0048388) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of retinoic acid receptor signaling pathway (GO:0048386) 6 0 .59 - < 0.01 1.00E00 1.00E00 mesendoderm development (GO:0048382) 6 0 .59 - < 0.01 1.00E00 1.00E00 cornification (GO:0070268) 3 0 .30 - < 0.01 1.00E00 1.00E00 oncosis (GO:0070267) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of endothelial cell activation (GO:1904988) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of endothelial cell activation (GO:1904987) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-serine dephosphorylation (GO:0070262) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 negative regulation of defense response to virus by host (GO:0050689) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of endosome organization (GO:1904980) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of mRNA processing (GO:0050686) 31 0 3.07 - < 0.01 1.09E-01 9.06E-01 regulation of lateral mesodermal cell fate specification (GO:0048378) 2 0 .20 - < 0.01 1.00E00 1.00E00 lateral mesodermal cell differentiation (GO:0048371) 1 0 .10 - < 0.01 1.00E00 1.00E00 lateral mesoderm formation (GO:0048370) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of mucus secretion (GO:0070257) 10 0 .99 - < 0.01 1.00E00 1.00E00 negative regulation of mucus secretion (GO:0070256) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of endosome organization (GO:1904978) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mucus secretion (GO:0070255) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 lymphatic endothelial cell migration (GO:1904977) 1 0 .10 - < 0.01 1.00E00 1.00E00 mucus secretion (GO:0070254) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to bleomycin (GO:1904976) 2 0 .20 - < 0.01 1.00E00 1.00E00 somatostatin secretion (GO:0070253) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to bleomycin (GO:1904975) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of viral translation (GO:1904973) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of viral translation (GO:1904971) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of urothelial cell proliferation (GO:0050677) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of urothelial cell proliferation (GO:0050675) 1 0 .10 - < 0.01 1.00E00 1.00E00 urothelial cell proliferation (GO:0050674) 1 0 .10 - < 0.01 1.00E00 1.00E00 lateral mesoderm morphogenesis (GO:0048369) 1 0 .10 - < 0.01 1.00E00 1.00E00 lateral mesoderm development (GO:0048368) 10 0 .99 - < 0.01 1.00E00 1.00E00 negative regulation of peptidyl-lysine crotonylation (GO:0120094) 1 0 .10 - < 0.01 1.00E00 1.00E00 amylase secretion (GO:0036394) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of peptidyl-lysine crotonylation (GO:0120093) 1 0 .10 - < 0.01 1.00E00 1.00E00 thymocyte apoptotic process (GO:0070242) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of cytochrome-c oxidase activity (GO:1904960) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of homocysteine metabolic process (GO:0050668) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of homocysteine metabolic process (GO:0050666) 1 0 .10 - < 0.01 1.00E00 1.00E00 paraxial mesoderm structural organization (GO:0048352) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cytochrome-c oxidase activity (GO:1904959) 9 0 .89 - < 0.01 1.00E00 1.00E00 positive regulation of midbrain dopaminergic neuron differentiation (GO:1904958) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of microfilament motor activity (GO:0120080) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of midbrain dopaminergic neuron differentiation (GO:1904956) 4 0 .40 - < 0.01 1.00E00 1.00E00 dermatan sulfate proteoglycan metabolic process (GO:0050655) 7 0 .69 - < 0.01 1.00E00 1.00E00 dermatan sulfate proteoglycan biosynthetic process (GO:0050651) 5 0 .49 - < 0.01 1.00E00 1.00E00 paraxial mesodermal cell fate commitment (GO:0048343) 1 0 .10 - < 0.01 1.00E00 1.00E00 paraxial mesodermal cell differentiation (GO:0048342) 1 0 .10 - < 0.01 1.00E00 1.00E00 microtubule polymerization based movement (GO:0099098) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of microfilament motor activity (GO:0120079) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell adhesion involved in sprouting angiogenesis (GO:0120078) 1 0 .10 - < 0.01 1.00E00 1.00E00 calcitriol biosynthetic process from calciol (GO:0036378) 3 0 .30 - < 0.01 1.00E00 1.00E00 angiogenic sprout fusion (GO:0120077) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of pyloric antrum smooth muscle contraction (GO:0120072) 1 0 .10 - < 0.01 1.00E00 1.00E00 midbrain dopaminergic neuron differentiation (GO:1904948) 4 0 .40 - < 0.01 1.00E00 1.00E00 opsin transport (GO:0036372) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of pyloric antrum smooth muscle contraction (GO:0120071) 1 0 .10 - < 0.01 1.00E00 1.00E00 folate import into mitochondrion (GO:1904947) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to T-tubule (GO:0036371) 2 0 .20 - < 0.01 1.00E00 1.00E00 sulfide oxidation, using sulfide:quinone oxidoreductase (GO:0070221) 1 0 .10 - < 0.01 1.00E00 1.00E00 mesoderm structural organization (GO:0048338) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of mesodermal cell fate specification (GO:0048337) 1 0 .10 - < 0.01 1.00E00 1.00E00 axonal transport of messenger ribonucleoprotein complex (GO:0099088) 1 0 .10 - < 0.01 1.00E00 1.00E00 anterograde axonal transport of messenger ribonucleoprotein complex (GO:0099087) 1 0 .10 - < 0.01 1.00E00 1.00E00 transcription factor catabolic process (GO:0036369) 1 0 .10 - < 0.01 1.00E00 1.00E00 light adaption (GO:0036367) 1 0 .10 - < 0.01 1.00E00 1.00E00 transforming growth factor beta1 activation (GO:0036364) 1 0 .10 - < 0.01 1.00E00 1.00E00 transforming growth factor beta activation (GO:0036363) 2 0 .20 - < 0.01 1.00E00 1.00E00 planar cell polarity pathway involved in axon guidance (GO:1904938) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of gastric emptying (GO:0120061) 1 0 .10 - < 0.01 1.00E00 1.00E00 sensory neuron migration (GO:1904937) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of gastric emptying (GO:0120060) 1 0 .10 - < 0.01 1.00E00 1.00E00 interneuron migration (GO:1904936) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein poly-ADP-ribosylation (GO:0070212) 8 0 .79 - < 0.01 1.00E00 1.00E00 axial mesoderm formation (GO:0048320) 2 0 .20 - < 0.01 1.00E00 1.00E00 renal potassium excretion (GO:0036359) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of small intestinal transit (GO:0120058) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrion-derived vesicle mediated transport (GO:0099075) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of small intestinal transit (GO:0120057) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrion to lysosome transport (GO:0099074) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein heterotrimerization (GO:0070208) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone H2A-K119 monoubiquitination (GO:0036353) 9 0 .89 - < 0.01 1.00E00 1.00E00 histone H2A-K15 ubiquitination (GO:0036352) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone H2A-K13 ubiquitination (GO:0036351) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of establishment of protein localization to telomere (GO:0070203) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization (GO:1904925) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 regulation of establishment of protein localization to chromosome (GO:0070202) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 negative regulation of mitophagy in response to mitochondrial depolarization (GO:1904924) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of autophagy of mitochondrion in response to mitochondrial depolarization (GO:1904923) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 establishment of protein localization to telomere (GO:0070200) 5 0 .49 - < 0.01 1.00E00 1.00E00 axial mesoderm morphogenesis (GO:0048319) 4 0 .40 - < 0.01 1.00E00 1.00E00 axial mesoderm development (GO:0048318) 8 0 .79 - < 0.01 1.00E00 1.00E00 Golgi inheritance (GO:0048313) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 snRNA (adenine-N6)-methylation (GO:0120049) 2 0 .20 - < 0.01 1.00E00 1.00E00 stereocilium maintenance (GO:0120045) 1 0 .10 - < 0.01 1.00E00 1.00E00 psychomotor behavior (GO:0036343) 3 0 .30 - < 0.01 1.00E00 1.00E00 post-anal tail morphogenesis (GO:0036342) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 negative regulation of establishment of RNA localization to telomere (GO:1904911) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of establishment of RNA localization to telomere (GO:1904910) 1 0 .10 - < 0.01 1.00E00 1.00E00 organelle inheritance (GO:0048308) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 lymphocyte adhesion to endothelial cell of high endothelial venule (GO:0036339) 1 0 .10 - < 0.01 1.00E00 1.00E00 intestinal stem cell homeostasis (GO:0036335) 2 0 .20 - < 0.01 1.00E00 1.00E00 epidermal stem cell homeostasis (GO:0036334) 2 0 .20 - < 0.01 1.00E00 1.00E00 vesicle scission (GO:0099050) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric (GO:1904908) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of maintenance of mitotic sister chromatid cohesion, telomeric (GO:1904907) 2 0 .20 - < 0.01 1.00E00 1.00E00 avascular cornea development in camera-type eye (GO:0036331) 1 0 .10 - < 0.01 1.00E00 1.00E00 ESCRT III complex disassembly (GO:1904903) 1 0 .10 - < 0.01 1.00E00 1.00E00 vesicle tethering to endoplasmic reticulum (GO:0099044) 2 0 .20 - < 0.01 1.00E00 1.00E00 vascular endothelial growth factor receptor-3 signaling pathway (GO:0036325) 1 0 .10 - < 0.01 1.00E00 1.00E00 vascular endothelial growth factor receptor-2 signaling pathway (GO:0036324) 5 0 .49 - < 0.01 1.00E00 1.00E00 vesicle tethering to Golgi (GO:0099041) 4 0 .40 - < 0.01 1.00E00 1.00E00 vascular endothelial growth factor receptor-1 signaling pathway (GO:0036323) 1 0 .10 - < 0.01 1.00E00 1.00E00 ghrelin secretion (GO:0036321) 1 0 .10 - < 0.01 1.00E00 1.00E00 palmitic acid biosynthetic process (GO:1900535) 1 0 .10 - < 0.01 1.00E00 1.00E00 palmitic acid metabolic process (GO:1900533) 1 0 .10 - < 0.01 1.00E00 1.00E00 SREBP-SCAP complex retention in endoplasmic reticulum (GO:0036316) 2 0 .20 - < 0.01 1.00E00 1.00E00 intermembrane lipid transfer (GO:0120009) 6 0 .59 - < 0.01 1.00E00 1.00E00 protein localization to M-band (GO:0036309) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of glutamatergic neuron differentiation (GO:0120008) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of glutamatergic neuron differentiation (GO:0120006) 1 0 .10 - < 0.01 1.00E00 1.00E00 ameloblast differentiation (GO:0036305) 1 0 .10 - < 0.01 1.00E00 1.00E00 vesicle tethering (GO:0099022) 7 0 .69 - < 0.01 1.00E00 1.00E00 umbilical cord morphogenesis (GO:0036304) 2 0 .20 - < 0.01 1.00E00 1.00E00 lymph vessel morphogenesis (GO:0036303) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 atrioventricular canal development (GO:0036302) 8 0 .79 - < 0.01 1.00E00 1.00E00 mRNA 5'-splice site recognition (GO:0000395) 5 0 .49 - < 0.01 1.00E00 1.00E00 spliceosomal conformational changes to generate catalytic conformation (GO:0000393) 5 0 .49 - < 0.01 1.00E00 1.00E00 neuronal dense core vesicle exocytosis (GO:0099011) 5 0 .49 - < 0.01 1.00E00 1.00E00 spliceosomal complex disassembly (GO:0000390) 2 0 .20 - < 0.01 1.00E00 1.00E00 mRNA 3'-splice site recognition (GO:0000389) 2 0 .20 - < 0.01 1.00E00 1.00E00 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) (GO:0000388) 1 0 .10 - < 0.01 1.00E00 1.00E00 alternative mRNA splicing, via spliceosome (GO:0000380) 21 0 2.08 - < 0.01 2.52E-01 1.00E00 tRNA-type intron splice site recognition and cleavage (GO:0000379) 3 0 .30 - < 0.01 1.00E00 1.00E00 RNA exon ligation (GO:0000378) 1 0 .10 - < 0.01 1.00E00 1.00E00 parathyroid hormone secretion (GO:0035898) 2 0 .20 - < 0.01 1.00E00 1.00E00 exit from host cell (GO:0035891) 9 0 .89 - < 0.01 1.00E00 1.00E00 exit from host (GO:0035890) 9 0 .89 - < 0.01 1.00E00 1.00E00 generation of catalytic spliceosome for second transesterification step (GO:0000350) 2 0 .20 - < 0.01 1.00E00 1.00E00 aortic smooth muscle cell differentiation (GO:0035887) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of protein homodimerization activity (GO:0043496) 1 0 .10 - < 0.01 1.00E00 1.00E00 enteroendocrine cell differentiation (GO:0035883) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 amacrine cell differentiation (GO:0035881) 4 0 .40 - < 0.01 1.00E00 1.00E00 malate-aspartate shuttle (GO:0043490) 5 0 .49 - < 0.01 1.00E00 1.00E00 embryonic nail plate morphogenesis (GO:0035880) 1 0 .10 - < 0.01 1.00E00 1.00E00 generation of catalytic spliceosome for first transesterification step (GO:0000349) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to flavonoid (GO:1905396) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to flavonoid (GO:1905395) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of helicase activity (GO:0051097) 3 0 .30 - < 0.01 1.00E00 1.00E00 nail development (GO:0035878) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of helicase activity (GO:0051096) 6 0 .59 - < 0.01 1.00E00 1.00E00 histone exchange (GO:0043486) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 regulation of helicase activity (GO:0051095) 9 0 .89 - < 0.01 1.00E00 1.00E00 endosome to pigment granule transport (GO:0043485) 10 0 .99 - < 0.01 1.00E00 1.00E00 cellular response to copper ion starvation (GO:0035874) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular pigment accumulation (GO:0043482) 10 0 .99 - < 0.01 1.00E00 1.00E00 protein deneddylation (GO:0000338) 10 0 .99 - < 0.01 1.00E00 1.00E00 protein localization to presynapse (GO:1905383) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of snRNA transcription by RNA polymerase II (GO:1905382) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of snRNA transcription by RNA polymerase II (GO:1905381) 1 0 .10 - < 0.01 1.00E00 1.00E00 constitutive protein ectodomain proteolysis (GO:0051089) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of snRNA transcription by RNA polymerase II (GO:1905380) 4 0 .40 - < 0.01 1.00E00 1.00E00 chaperone mediated protein folding independent of cofactor (GO:0051086) 1 0 .10 - < 0.01 1.00E00 1.00E00 pigment accumulation (GO:0043476) 10 0 .99 - < 0.01 1.00E00 1.00E00 cellular response to potassium ion (GO:0035865) 7 0 .69 - < 0.01 1.00E00 1.00E00 pigment metabolic process involved in pigmentation (GO:0043474) 1 0 .10 - < 0.01 1.00E00 1.00E00 innate vocalization behavior (GO:0098582) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to potassium ion (GO:0035864) 7 0 .69 - < 0.01 1.00E00 1.00E00 dITP catabolic process (GO:0035863) 1 0 .10 - < 0.01 1.00E00 1.00E00 nuclear membrane disassembly (GO:0051081) 5 0 .49 - < 0.01 1.00E00 1.00E00 dITP metabolic process (GO:0035862) 1 0 .10 - < 0.01 1.00E00 1.00E00 re-entry into mitotic cell cycle (GO:0000320) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of fermentation (GO:0043465) 4 0 .40 - < 0.01 1.00E00 1.00E00 chromosome passenger complex localization to spindle midzone (GO:0035853) 1 0 .10 - < 0.01 1.00E00 1.00E00 proton-transporting ATP synthase complex assembly (GO:0043461) 7 0 .69 - < 0.01 1.00E00 1.00E00 chromatin disassembly (GO:0031498) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 regulation of mating type switching (GO:0031494) 3 0 .30 - < 0.01 1.00E00 1.00E00 dihydrolipoamide metabolic process (GO:0051068) 1 0 .10 - < 0.01 1.00E00 1.00E00 uterine epithelium development (GO:0035847) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of secondary metabolic process (GO:0043455) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 photoreceptor cell outer segment organization (GO:0035845) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 cloaca development (GO:0035844) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein localization to meiotic spindle (GO:1905359) 1 0 .10 - < 0.01 1.00E00 1.00E00 spine apparatus assembly (GO:1905355) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to singlet oxygen (GO:0000304) 1 0 .10 - < 0.01 1.00E00 1.00E00 pericyte cell migration (GO:1905351) 1 0 .10 - < 0.01 1.00E00 1.00E00 retrograde transport, vesicle recycling within Golgi (GO:0000301) 1 0 .10 - < 0.01 1.00E00 1.00E00 ciliary transition zone assembly (GO:1905349) 2 0 .20 - < 0.01 1.00E00 1.00E00 prostaglandin catabolic process (GO:1905344) 2 0 .20 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-serine acetylation (GO:0017198) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to kinetochore (GO:1905342) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to kinetochore (GO:1905341) 1 0 .10 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-methionine acetylation (GO:0017196) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of protein localization to kinetochore (GO:1905340) 4 0 .40 - < 0.01 1.00E00 1.00E00 red, far-red light phototransduction (GO:0009585) 1 0 .10 - < 0.01 1.00E00 1.00E00 detection of visible light (GO:0009584) 21 0 2.08 - < 0.01 2.52E-01 1.00E00 negative regulation of calcium-independent cell-cell adhesion (GO:0051042) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of calcium-independent cell-cell adhesion (GO:0051041) 1 0 .10 - < 0.01 1.00E00 1.00E00 gene conversion (GO:0035822) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of calcium-independent cell-cell adhesion (GO:0051040) 2 0 .20 - < 0.01 1.00E00 1.00E00 nuclear membrane reassembly (GO:0031468) 10 0 .99 - < 0.01 1.00E00 1.00E00 glycine betaine transport (GO:0031460) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of aggrephagy (GO:1905337) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of aggrephagy (GO:1905335) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of gastric motility (GO:1905333) 3 0 .30 - < 0.01 1.00E00 1.00E00 peptidyl-glutamic acid carboxylation (GO:0017187) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of morphogenesis of an epithelium (GO:1905331) 7 0 .69 - < 0.01 1.00E00 1.00E00 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase (GO:0017186) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of transcription involved in meiotic cell cycle (GO:0051039) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-lysine hydroxylation (GO:0017185) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of transcription involved in meiotic cell cycle (GO:0051038) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of transcription involved in meiotic cell cycle (GO:0051037) 2 0 .20 - < 0.01 1.00E00 1.00E00 peptidyl-diphthamide biosynthetic process from peptidyl-histidine (GO:0017183) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of endosome size (GO:0051036) 4 0 .40 - < 0.01 1.00E00 1.00E00 de novo centriole assembly involved in multi-ciliated epithelial cell differentiation (GO:0098535) 5 0 .49 - < 0.01 1.00E00 1.00E00 peptidyl-diphthamide metabolic process (GO:0017182) 6 0 .59 - < 0.01 1.00E00 1.00E00 centriole assembly (GO:0098534) 25 0 2.47 - < 0.01 1.63E-01 1.00E00 negative regulation of renal sodium excretion (GO:0035814) 7 0 .69 - < 0.01 1.00E00 1.00E00 tRNA transport (GO:0051031) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of strand invasion (GO:0098530) 1 0 .10 - < 0.01 1.00E00 1.00E00 renal sodium excretion (GO:0035812) 1 0 .10 - < 0.01 1.00E00 1.00E00 snRNA transport (GO:0051030) 3 0 .30 - < 0.01 1.00E00 1.00E00 anthranilate metabolic process (GO:0043420) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of urine volume (GO:0035810) 10 0 .99 - < 0.01 1.00E00 1.00E00 positive regulation of heterochromatin assembly (GO:0031453) 10 0 .99 - < 0.01 1.00E00 1.00E00 negative regulation of heterochromatin assembly (GO:0031452) 4 0 .40 - < 0.01 1.00E00 1.00E00 telomerase holoenzyme complex assembly (GO:1905323) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of mesenchymal stem cell migration (GO:1905322) 3 0 .30 - < 0.01 1.00E00 1.00E00 neuromuscular junction development, skeletal muscle fiber (GO:0098529) 1 0 .10 - < 0.01 1.00E00 1.00E00 skeletal muscle fiber differentiation (GO:0098528) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal stem cell migration (GO:1905320) 3 0 .30 - < 0.01 1.00E00 1.00E00 homocysteine catabolic process (GO:0043418) 2 0 .20 - < 0.01 1.00E00 1.00E00 chiasma assembly (GO:0051026) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle tissue regeneration (GO:0043416) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of skeletal muscle tissue regeneration (GO:0043415) 4 0 .40 - < 0.01 1.00E00 1.00E00 egg coat formation (GO:0035803) 1 0 .10 - < 0.01 1.00E00 1.00E00 adrenal cortex formation (GO:0035802) 1 0 .10 - < 0.01 1.00E00 1.00E00 adrenal cortex development (GO:0035801) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of fast-twitch skeletal muscle fiber contraction (GO:0031448) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of fast-twitch skeletal muscle fiber contraction (GO:0031446) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of heterochromatin assembly (GO:0031445) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 slow-twitch skeletal muscle fiber contraction (GO:0031444) 1 0 .10 - < 0.01 1.00E00 1.00E00 fast-twitch skeletal muscle fiber contraction (GO:0031443) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of mRNA 3'-end processing (GO:0031441) 8 0 .79 - < 0.01 1.00E00 1.00E00 inferior endocardial cushion morphogenesis (GO:1905317) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis (GO:1905312) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis (GO:1905310) 2 0 .20 - < 0.01 1.00E00 1.00E00 microtubule severing (GO:0051013) 5 0 .49 - < 0.01 1.00E00 1.00E00 microtubule sliding (GO:0051012) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of mRNA cleavage (GO:0031439) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mRNA cleavage (GO:0031437) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cohesin loading (GO:1905309) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac myofibril assembly (GO:1905305) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cardiac myofibril assembly (GO:1905304) 1 0 .10 - < 0.01 1.00E00 1.00E00 calcium-ion regulated exocytosis (GO:0017156) 33 0 3.26 - < 0.01 6.95E-02 7.23E-01 polynucleotide 5' dephosphorylation (GO:0098507) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of lipoprotein lipase activity (GO:0051005) 5 0 .49 - < 0.01 1.00E00 1.00E00 response to methotrexate (GO:0031427) 1 0 .10 - < 0.01 1.00E00 1.00E00 keratinization (GO:0031424) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 insecticide metabolic process (GO:0017143) 1 0 .10 - < 0.01 1.00E00 1.00E00 establishment of protein localization to chromosome (GO:0070199) 10 0 .99 - < 0.01 1.00E00 1.00E00 protein localization to chromosome, telomeric region (GO:0070198) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 meiotic attachment of telomere to nuclear envelope (GO:0070197) 2 0 .20 - < 0.01 1.00E00 1.00E00 synaptonemal complex disassembly (GO:0070194) 2 0 .20 - < 0.01 1.00E00 1.00E00 nucleologenesis (GO:0017126) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitochondrial tryptophanyl-tRNA aminoacylation (GO:0070183) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of Golgi to plasma membrane CFTR protein transport (GO:0042999) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of Golgi to plasma membrane protein transport (GO:0042998) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of Golgi to plasma membrane protein transport (GO:0042997) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of Golgi to plasma membrane protein transport (GO:0042996) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 negative regulation of isotype switching to IgA isotypes (GO:0048297) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of isotype switching to IgE isotypes (GO:0048295) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of isotype switching to IgE isotypes (GO:0048294) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of isotype switching to IgE isotypes (GO:0048293) 7 0 .69 - < 0.01 1.00E00 1.00E00 isotype switching to IgG isotypes (GO:0048291) 1 0 .10 - < 0.01 1.00E00 1.00E00 D-serine biosynthetic process (GO:0070179) 1 0 .10 - < 0.01 1.00E00 1.00E00 D-serine metabolic process (GO:0070178) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of hepatic stellate cell proliferation (GO:1904899) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of enamel mineralization (GO:0070175) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of hepatic stellate cell proliferation (GO:1904897) 1 0 .10 - < 0.01 1.00E00 1.00E00 ESCRT complex disassembly (GO:1904896) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of enamel mineralization (GO:0070173) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of tooth mineralization (GO:0070172) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of tooth mineralization (GO:0070171) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of tooth mineralization (GO:0070170) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of amyloid precursor protein biosynthetic process (GO:0042985) 7 0 .69 - < 0.01 1.00E00 1.00E00 amyloid precursor protein biosynthetic process (GO:0042983) 1 0 .10 - < 0.01 1.00E00 1.00E00 vesicle fusion with Golgi apparatus (GO:0048280) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of telomerase catalytic core complex assembly (GO:1904884) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of telomerase catalytic core complex assembly (GO:1904882) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to hydrogen sulfide (GO:1904881) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to hydrogen sulfide (GO:1904880) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitochondrial seryl-tRNA aminoacylation (GO:0070158) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (GO:1904879) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of DNA ligase activity (GO:1904877) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of DNA ligase activity (GO:1904875) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of telomerase RNA localization to Cajal body (GO:1904874) 4 0 .40 - < 0.01 1.00E00 1.00E00 mitochondrial glycyl-tRNA aminoacylation (GO:0070150) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of telomerase RNA localization to Cajal body (GO:1904872) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to Cajal body (GO:1904871) 2 0 .20 - < 0.01 1.00E00 1.00E00 determination of ventral identity (GO:0048264) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of centriole-centriole cohesion (GO:0030997) 3 0 .30 - < 0.01 1.00E00 1.00E00 determination of dorsal identity (GO:0048263) 4 0 .40 - < 0.01 1.00E00 1.00E00 determination of dorsal/ventral asymmetry (GO:0048262) 5 0 .49 - < 0.01 1.00E00 1.00E00 recombinational interstrand cross-link repair (GO:0036298) 2 0 .20 - < 0.01 1.00E00 1.00E00 interstrand cross-link repair (GO:0036297) 30 0 2.97 - < 0.01 1.07E-01 8.98E-01 regulation of protein localization to Cajal body (GO:1904869) 2 0 .20 - < 0.01 1.00E00 1.00E00 DNA rewinding (GO:0036292) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial asparaginyl-tRNA aminoacylation (GO:0070145) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to Cajal body (GO:1904867) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial alanyl-tRNA aminoacylation (GO:0070143) 1 0 .10 - < 0.01 1.00E00 1.00E00 synaptic vesicle budding (GO:0070142) 10 0 .99 - < 0.01 1.00E00 1.00E00 negative regulation of beta-catenin-TCF complex assembly (GO:1904864) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of beta-catenin-TCF complex assembly (GO:1904863) 2 0 .20 - < 0.01 1.00E00 1.00E00 inhibitory synapse assembly (GO:1904862) 6 0 .59 - < 0.01 1.00E00 1.00E00 snoRNA localization (GO:0048254) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial translation (GO:0070131) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 negative regulation of mitochondrial translation (GO:0070130) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of establishment of protein localization to telomere (GO:1904851) 10 0 .99 - < 0.01 1.00E00 1.00E00 negative regulation of establishment of protein localization to telomere (GO:1904850) 1 0 .10 - < 0.01 1.00E00 1.00E00 glucoside transport (GO:0042946) 1 0 .10 - < 0.01 1.00E00 1.00E00 D-serine transport (GO:0042942) 2 0 .20 - < 0.01 1.00E00 1.00E00 epinephrine secretion (GO:0048242) 1 0 .10 - < 0.01 1.00E00 1.00E00 sperm capacitation (GO:0048240) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 thiamine pyrophosphate transmembrane transport (GO:0030974) 2 0 .20 - < 0.01 1.00E00 1.00E00 retrograde protein transport, ER to cytosol (GO:0030970) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 response to 5-fluorouracil (GO:0036275) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cell chemotaxis to fibroblast growth factor (GO:1904849) 3 0 .30 - < 0.01 1.00E00 1.00E00 mitochondrial translational termination (GO:0070126) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of cell chemotaxis to fibroblast growth factor (GO:1904847) 4 0 .40 - < 0.01 1.00E00 1.00E00 mitochondrial translational elongation (GO:0070125) 4 0 .40 - < 0.01 1.00E00 1.00E00 mitochondrial translational initiation (GO:0070124) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of male germ-line stem cell asymmetric division (GO:1904840) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of DNA recombination at telomere (GO:0048239) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of diacylglycerol biosynthetic process (GO:1900480) 1 0 .10 - < 0.01 1.00E00 1.00E00 swimming (GO:0036268) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-arginine hydroxylation (GO:0030961) 1 0 .10 - < 0.01 1.00E00 1.00E00 RNA (guanine-N7)-methylation (GO:0036265) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of male germ-line stem cell asymmetric division (GO:1904838) 1 0 .10 - < 0.01 1.00E00 1.00E00 7-methylguanosine cap hypermethylation (GO:0036261) 1 0 .10 - < 0.01 1.00E00 1.00E00 RNA capping (GO:0036260) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of aortic smooth muscle cell differentiation (GO:1904831) 2 0 .20 - < 0.01 1.00E00 1.00E00 glucocorticoid receptor signaling pathway (GO:0042921) 4 0 .40 - < 0.01 1.00E00 1.00E00 plasma membrane to endosome transport (GO:0048227) 7 0 .69 - < 0.01 1.00E00 1.00E00 astral microtubule nucleation (GO:0030954) 1 0 .10 - < 0.01 1.00E00 1.00E00 astral microtubule organization (GO:0030953) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 multivesicular body assembly (GO:0036258) 3 0 .30 - < 0.01 1.00E00 1.00E00 establishment or maintenance of microtubule cytoskeleton polarity (GO:0030951) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of aortic smooth muscle cell differentiation (GO:1904829) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of hydrogen sulfide biosynthetic process (GO:1904828) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of hydrogen sulfide biosynthetic process (GO:1904826) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to microtubule plus-end (GO:1904825) 4 0 .40 - < 0.01 1.00E00 1.00E00 peroxisome transport along microtubule (GO:0036250) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of chemokine-mediated signaling pathway (GO:0070101) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of chemokine-mediated signaling pathway (GO:0070100) 6 0 .59 - < 0.01 1.00E00 1.00E00 alkanesulfonate transport (GO:0042918) 6 0 .59 - < 0.01 1.00E00 1.00E00 inter-Golgi cisterna vesicle-mediated transport (GO:0048219) 1 0 .10 - < 0.01 1.00E00 1.00E00 Golgi vesicle prefusion complex stabilization (GO:0048213) 2 0 .20 - < 0.01 1.00E00 1.00E00 Golgi vesicle docking (GO:0048211) 2 0 .20 - < 0.01 1.00E00 1.00E00 Golgi vesicle fusion to target membrane (GO:0048210) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular response to menadione (GO:0036245) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to chromosome, telomeric region (GO:1904816) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 negative regulation of protein localization to chromosome, telomeric region (GO:1904815) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein localization to chromosome, telomeric region (GO:1904814) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 rRNA acetylation involved in maturation of SSU-rRNA (GO:1904812) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of dense core granule transport (GO:1904811) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of long-term synaptic depression (GO:1900453) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of vesicle targeting, to, from or within Golgi (GO:0048209) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of glutamate receptor signaling pathway (GO:1900451) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of glutamate receptor signaling pathway (GO:1900450) 1 0 .10 - < 0.01 1.00E00 1.00E00 COPI coating of Golgi vesicle (GO:0048205) 4 0 .40 - < 0.01 1.00E00 1.00E00 Golgi transport vesicle coating (GO:0048200) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of dense core granule transport (GO:1904809) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of protein oxidation (GO:1904808) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein oxidation (GO:1904806) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of translation involved in cellular response to UV (GO:1904803) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of neuron remodeling (GO:1904800) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to nuclear inner membrane (GO:0036228) 2 0 .20 - < 0.01 1.00E00 1.00E00 peptidyl-serine acetylation (GO:0030920) 2 0 .20 - < 0.01 1.00E00 1.00E00 olfactory placode formation (GO:0030910) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular response to stem cell factor stimulus (GO:0036216) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to stem cell factor (GO:0036215) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of defense response to bacterium (GO:1900425) 4 0 .40 - < 0.01 1.00E00 1.00E00 protein splicing (GO:0030908) 1 0 .10 - < 0.01 1.00E00 1.00E00 notochord development (GO:0030903) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 spermine transport (GO:0000296) 1 0 .10 - < 0.01 1.00E00 1.00E00 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay (GO:0000294) 2 0 .20 - < 0.01 1.00E00 1.00E00 nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 negative regulation of cellular response to oxidative stress (GO:1900408) 3 0 .30 - < 0.01 1.00E00 1.00E00 M phase (GO:0000279) 9 0 .89 - < 0.01 1.00E00 1.00E00 mitochondrial fission (GO:0000266) 23 0 2.27 - < 0.01 2.61E-01 1.00E00 negative regulation of mitochondrial membrane permeability (GO:0035795) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway (GO:0035793) 3 0 .30 - < 0.01 1.00E00 1.00E00 platelet-derived growth factor receptor-beta signaling pathway (GO:0035791) 7 0 .69 - < 0.01 1.00E00 1.00E00 platelet-derived growth factor receptor-alpha signaling pathway (GO:0035790) 1 0 .10 - < 0.01 1.00E00 1.00E00 metanephric mesenchymal cell migration (GO:0035789) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of corticotropin-releasing hormone secretion (GO:0043397) 4 0 .40 - < 0.01 1.00E00 1.00E00 cell migration involved in metanephros development (GO:0035788) 2 0 .20 - < 0.01 1.00E00 1.00E00 cell migration involved in kidney development (GO:0035787) 3 0 .30 - < 0.01 1.00E00 1.00E00 CD4-positive, alpha-beta T cell costimulation (GO:0035783) 2 0 .20 - < 0.01 1.00E00 1.00E00 mature natural killer cell chemotaxis (GO:0035782) 1 0 .10 - < 0.01 1.00E00 1.00E00 CD86 biosynthetic process (GO:0035781) 2 0 .20 - < 0.01 1.00E00 1.00E00 CD80 biosynthetic process (GO:0035780) 1 0 .10 - < 0.01 1.00E00 1.00E00 spliceosomal tri-snRNP complex assembly (GO:0000244) 9 0 .89 - < 0.01 1.00E00 1.00E00 positive regulation of CAMKK-AMPK signaling cascade (GO:1905291) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of CAMKK-AMPK signaling cascade (GO:1905290) 1 0 .10 - < 0.01 1.00E00 1.00E00 mycotoxin catabolic process (GO:0043387) 2 0 .20 - < 0.01 1.00E00 1.00E00 mycotoxin metabolic process (GO:0043385) 2 0 .20 - < 0.01 1.00E00 1.00E00 insulin secretion involved in cellular response to glucose stimulus (GO:0035773) 8 0 .79 - < 0.01 1.00E00 1.00E00 interleukin-4-mediated signaling pathway (GO:0035771) 2 0 .20 - < 0.01 1.00E00 1.00E00 pachytene (GO:0000239) 2 0 .20 - < 0.01 1.00E00 1.00E00 leptotene (GO:0000237) 5 0 .49 - < 0.01 1.00E00 1.00E00 fibrous ring of heart morphogenesis (GO:1905285) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of retrograde transport, endosome to Golgi (GO:1905280) 1 0 .10 - < 0.01 1.00E00 1.00E00 memory T cell differentiation (GO:0043379) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of CD8-positive, alpha-beta T cell differentiation (GO:0043377) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of epithelial tube formation (GO:1905278) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of epithelial tube formation (GO:1905276) 7 0 .69 - < 0.01 1.00E00 1.00E00 beta selection (GO:0043366) 3 0 .30 - < 0.01 1.00E00 1.00E00 lysosomal lumen pH elevation (GO:0035752) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to myelin sheath abaxonal region (GO:0035750) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of prostaglandin biosynthetic process (GO:0031393) 2 0 .20 - < 0.01 1.00E00 1.00E00 endonucleolytic cleavage involved in tRNA processing (GO:1905267) 2 0 .20 - < 0.01 1.00E00 1.00E00 natural killer cell chemotaxis (GO:0035747) 1 0 .10 - < 0.01 1.00E00 1.00E00 T-helper 2 cell cytokine production (GO:0035745) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway (GO:1905259) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway (GO:1905258) 2 0 .20 - < 0.01 1.00E00 1.00E00 intraciliary transport involved in cilium assembly (GO:0035735) 7 0 .69 - < 0.01 1.00E00 1.00E00 hepatic stellate cell activation (GO:0035733) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to 3,3',5-triiodo-L-thyronine (GO:1905243) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to 3,3',5-triiodo-L-thyronine (GO:1905242) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein unfolding (GO:0043335) 1 0 .10 - < 0.01 1.00E00 1.00E00 interleukin-12-mediated signaling pathway (GO:0035722) 2 0 .20 - < 0.01 1.00E00 1.00E00 intraciliary retrograde transport (GO:0035721) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 intraciliary anterograde transport (GO:0035720) 5 0 .49 - < 0.01 1.00E00 1.00E00 N-terminal protein amino acid modification (GO:0031365) 21 0 2.08 - < 0.01 2.52E-01 1.00E00 response to insecticide (GO:0017085) 5 0 .49 - < 0.01 1.00E00 1.00E00 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043328) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of natural killer cell degranulation (GO:0043323) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular response to nitrogen dioxide (GO:0035714) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to nitrogen dioxide (GO:0035713) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of natural killer cell degranulation (GO:0043322) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of natural killer cell degranulation (GO:0043321) 4 0 .40 - < 0.01 1.00E00 1.00E00 T-helper 2 cell activation (GO:0035712) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to thyrotropin-releasing hormone (GO:1905229) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to thyrotropin-releasing hormone (GO:1905225) 1 0 .10 - < 0.01 1.00E00 1.00E00 clathrin-coated pit assembly (GO:1905224) 2 0 .20 - < 0.01 1.00E00 1.00E00 epicardium morphogenesis (GO:1905223) 2 0 .20 - < 0.01 1.00E00 1.00E00 atrioventricular canal morphogenesis (GO:1905222) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of platelet formation (GO:1905221) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of cytotoxic T cell degranulation (GO:0043318) 1 0 .10 - < 0.01 1.00E00 1.00E00 memory T cell activation (GO:0035709) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of cytotoxic T cell degranulation (GO:0043317) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of eosinophil degranulation (GO:0043311) 2 0 .20 - < 0.01 1.00E00 1.00E00 monocyte homeostasis (GO:0035702) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of platelet formation (GO:1905219) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to astaxanthin (GO:1905217) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of RNA binding (GO:1905216) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of RNA binding (GO:1905215) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of RNA binding (GO:1905214) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 eosinophil degranulation (GO:0043308) 1 0 .10 - < 0.01 1.00E00 1.00E00 eosinophil activation (GO:0043307) 1 0 .10 - < 0.01 1.00E00 1.00E00 respiratory chain complex III assembly (GO:0017062) 8 0 .79 - < 0.01 1.00E00 1.00E00 7-methylguanosine RNA capping (GO:0009452) 8 0 .79 - < 0.01 1.00E00 1.00E00 gamma-aminobutyric acid catabolic process (GO:0009450) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of sulfur amino acid metabolic process (GO:0031337) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of sulfur amino acid metabolic process (GO:0031335) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of hydrogen peroxide-induced cell death (GO:1905206) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of connective tissue replacement (GO:1905205) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of connective tissue replacement (GO:1905204) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of connective tissue replacement (GO:1905203) 6 0 .59 - < 0.01 1.00E00 1.00E00 gamma-aminobutyric acid biosynthetic process (GO:0009449) 2 0 .20 - < 0.01 1.00E00 1.00E00 gamma-aminobutyric acid metabolic process (GO:0009448) 4 0 .40 - < 0.01 1.00E00 1.00E00 putrescine catabolic process (GO:0009447) 1 0 .10 - < 0.01 1.00E00 1.00E00 putrescine biosynthetic process (GO:0009446) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of RNA polymerase II transcription preinitiation complex assembly (GO:0017055) 1 0 .10 - < 0.01 1.00E00 1.00E00 putrescine metabolic process (GO:0009445) 7 0 .69 - < 0.01 1.00E00 1.00E00 pyruvate oxidation (GO:0009444) 1 0 .10 - < 0.01 1.00E00 1.00E00 pyridoxal 5'-phosphate salvage (GO:0009443) 1 0 .10 - < 0.01 1.00E00 1.00E00 glycolate metabolic process (GO:0009441) 1 0 .10 - < 0.01 1.00E00 1.00E00 methylglyoxal metabolic process (GO:0009438) 6 0 .59 - < 0.01 1.00E00 1.00E00 glyoxylate catabolic process (GO:0009436) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of chemokine-mediated signaling pathway (GO:0070099) 9 0 .89 - < 0.01 1.00E00 1.00E00 positive regulation of glucagon secretion (GO:0070094) 4 0 .40 - < 0.01 1.00E00 1.00E00 glucagon secretion (GO:0070091) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to water (GO:0009415) 9 0 .89 - < 0.01 1.00E00 1.00E00 response to water deprivation (GO:0009414) 3 0 .30 - < 0.01 1.00E00 1.00E00 Golgi vesicle budding (GO:0048194) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of neuron remodeling (GO:1904799) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of core promoter binding (GO:1904798) 6 0 .59 - < 0.01 1.00E00 1.00E00 toxin catabolic process (GO:0009407) 2 0 .20 - < 0.01 1.00E00 1.00E00 tear secretion (GO:0070075) 1 0 .10 - < 0.01 1.00E00 1.00E00 clustering of voltage-gated calcium channels (GO:0070073) 1 0 .10 - < 0.01 1.00E00 1.00E00 vacuolar proton-transporting V-type ATPase complex assembly (GO:0070072) 4 0 .40 - < 0.01 1.00E00 1.00E00 proton-transporting two-sector ATPase complex assembly (GO:0070071) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 proton-transporting V-type ATPase complex assembly (GO:0070070) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of shelterin complex assembly (GO:1904792) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of shelterin complex assembly (GO:1904790) 1 0 .10 - < 0.01 1.00E00 1.00E00 cysteine transport (GO:0042883) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein-tetrapyrrole linkage (GO:0017006) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein-heme linkage (GO:0017003) 1 0 .10 - < 0.01 1.00E00 1.00E00 NLRP1 inflammasome complex assembly (GO:1904784) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of NMDA glutamate receptor activity (GO:1904783) 8 0 .79 - < 0.01 1.00E00 1.00E00 'de novo' actin filament nucleation (GO:0070060) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to centrosome (GO:1904781) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to centrosome (GO:1904780) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of short-term neuronal synaptic plasticity (GO:0048174) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of long-term neuronal synaptic plasticity (GO:0048170) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of protein localization to centrosome (GO:1904779) 10 0 .99 - < 0.01 1.00E00 1.00E00 antisense RNA metabolic process (GO:0042868) 1 0 .10 - < 0.01 1.00E00 1.00E00 fused antrum stage (GO:0048165) 1 0 .10 - < 0.01 1.00E00 1.00E00 multi-layer follicle stage (GO:0048162) 1 0 .10 - < 0.01 1.00E00 1.00E00 primary follicle stage (GO:0048160) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of macroautophagy by TORC1 signaling (GO:1904766) 1 0 .10 - < 0.01 1.00E00 1.00E00 chaperone-mediated autophagy translocation complex disassembly (GO:1904764) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of myofibroblast differentiation (GO:1904762) 1 0 .10 - < 0.01 1.00E00 1.00E00 L-alanine catabolic process (GO:0042853) 1 0 .10 - < 0.01 1.00E00 1.00E00 L-alanine metabolic process (GO:0042851) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of vascular associated smooth muscle cell migration (GO:1904753) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to nucleolus (GO:1904751) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to nucleolus (GO:1904750) 1 0 .10 - < 0.01 1.00E00 1.00E00 D-xylose catabolic process (GO:0042843) 1 0 .10 - < 0.01 1.00E00 1.00E00 D-glucuronate catabolic process (GO:0042840) 1 0 .10 - < 0.01 1.00E00 1.00E00 fibroblast proliferation (GO:0048144) 3 0 .30 - < 0.01 1.00E00 1.00E00 thyroid gland development (GO:0030878) 20 0 1.98 - < 0.01 2.51E-01 1.00E00 osteoclast maturation (GO:0036179) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein localization to nucleolus (GO:1904749) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of apoptotic process involved in development (GO:1904746) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of telomeric DNA binding (GO:1904744) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of telomeric DNA binding (GO:1904743) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of telomeric DNA binding (GO:1904742) 4 0 .40 - < 0.01 1.00E00 1.00E00 protein arginylation (GO:0016598) 1 0 .10 - < 0.01 1.00E00 1.00E00 D-glucuronate metabolic process (GO:0042839) 1 0 .10 - < 0.01 1.00E00 1.00E00 spermatocyte division (GO:0048137) 2 0 .20 - < 0.01 1.00E00 1.00E00 male germ-line stem cell asymmetric division (GO:0048133) 3 0 .30 - < 0.01 1.00E00 1.00E00 female germ-line stem cell asymmetric division (GO:0048132) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of polarized epithelial cell differentiation (GO:0030862) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of polarized epithelial cell differentiation (GO:0030860) 2 0 .20 - < 0.01 1.00E00 1.00E00 phenotypic switching (GO:0036166) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of electron transfer activity (GO:1904734) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of electron transfer activity (GO:1904732) 9 0 .89 - < 0.01 1.00E00 1.00E00 positive regulation of intestinal lipid absorption (GO:1904731) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of secondary metabolite biosynthetic process (GO:1900378) 6 0 .59 - < 0.01 1.00E00 1.00E00 nucleosome positioning (GO:0016584) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of secondary metabolite biosynthetic process (GO:1900377) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of secondary metabolite biosynthetic process (GO:1900376) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 catecholamine secretion (GO:0050432) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of RNA interference (GO:1900370) 1 0 .10 - < 0.01 1.00E00 1.00E00 polarized epithelial cell differentiation (GO:0030859) 19 0 1.88 - < 0.01 4.08E-01 1.00E00 inner dynein arm assembly (GO:0036159) 10 0 .99 - < 0.01 1.00E00 1.00E00 outer dynein arm assembly (GO:0036158) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 regulation of intestinal lipid absorption (GO:1904729) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of Wnt-Frizzled-LRP5/6 complex assembly (GO:1904723) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone deubiquitination (GO:0016578) 22 0 2.18 - < 0.01 2.56E-01 1.00E00 negative regulation of RNA interference (GO:1900369) 2 0 .20 - < 0.01 1.00E00 1.00E00 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process (GO:0050428) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of RNA interference (GO:1900368) 3 0 .30 - < 0.01 1.00E00 1.00E00 3'-phosphoadenosine 5'-phosphosulfate metabolic process (GO:0050427) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of mRNA polyadenylation (GO:1900364) 8 0 .79 - < 0.01 1.00E00 1.00E00 phospholipase C-inhibiting G protein-coupled receptor signaling pathway (GO:0030845) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of intermediate filament depolymerization (GO:0030844) 1 0 .10 - < 0.01 1.00E00 1.00E00 phosphatidylinositol acyl-chain remodeling (GO:0036149) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of intermediate filament depolymerization (GO:0030842) 1 0 .10 - < 0.01 1.00E00 1.00E00 phosphatidylglycerol acyl-chain remodeling (GO:0036148) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to mycotoxin (GO:0036146) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of AMPA glutamate receptor clustering (GO:1904719) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of AMPA glutamate receptor clustering (GO:1904717) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of chaperone-mediated autophagy (GO:1904716) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of Wnt-Frizzled-LRP5/6 complex assembly (GO:1904711) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of granulosa cell apoptotic process (GO:1904710) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein import into peroxisome matrix, translocation (GO:0016561) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein import into peroxisome matrix, docking (GO:0016560) 4 0 .40 - < 0.01 1.00E00 1.00E00 establishment of body hair planar orientation (GO:0048105) 4 0 .40 - < 0.01 1.00E00 1.00E00 establishment of body hair or bristle planar orientation (GO:0048104) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of actin filament depolymerization (GO:0030836) 10 0 .99 - < 0.01 1.00E00 1.00E00 peptidyl-histidine hydroxylation (GO:0036138) 1 0 .10 - < 0.01 1.00E00 1.00E00 Schwann cell migration (GO:0036135) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of granulosa cell apoptotic process (GO:1904709) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of granulosa cell apoptotic process (GO:1904708) 3 0 .30 - < 0.01 1.00E00 1.00E00 peroxisome fission (GO:0016559) 9 0 .89 - < 0.01 1.00E00 1.00E00 protein import into peroxisome matrix (GO:0016558) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 regulation of protein localization to adherens junction (GO:1904702) 1 0 .10 - < 0.01 1.00E00 1.00E00 peroxisome membrane biogenesis (GO:0016557) 4 0 .40 - < 0.01 1.00E00 1.00E00 mRNA modification (GO:0016556) 27 0 2.67 - < 0.01 1.68E-01 1.00E00 cytidine to uridine editing (GO:0016554) 5 0 .49 - < 0.01 1.00E00 1.00E00 base conversion or substitution editing (GO:0016553) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 histone H3-K9 trimethylation (GO:0036124) 6 0 .59 - < 0.01 1.00E00 1.00E00 histone H3-K9 dimethylation (GO:0036123) 3 0 .30 - < 0.01 1.00E00 1.00E00 ATP-dependent chaperone mediated protein folding (GO:0061992) 1 0 .10 - < 0.01 1.00E00 1.00E00 long-chain fatty-acyl-CoA catabolic process (GO:0036116) 1 0 .10 - < 0.01 1.00E00 1.00E00 fatty-acyl-CoA catabolic process (GO:0036115) 4 0 .40 - < 0.01 1.00E00 1.00E00 medium-chain fatty-acyl-CoA catabolic process (GO:0036114) 2 0 .20 - < 0.01 1.00E00 1.00E00 very long-chain fatty-acyl-CoA catabolic process (GO:0036113) 1 0 .10 - < 0.01 1.00E00 1.00E00 medium-chain fatty-acyl-CoA metabolic process (GO:0036112) 3 0 .30 - < 0.01 1.00E00 1.00E00 very long-chain fatty-acyl-CoA metabolic process (GO:0036111) 2 0 .20 - < 0.01 1.00E00 1.00E00 intein-mediated protein splicing (GO:0016539) 1 0 .10 - < 0.01 1.00E00 1.00E00 mandibular condyle articular cartilage development (GO:0061978) 1 0 .10 - < 0.01 1.00E00 1.00E00 temporomandibular joint articular cartilage development (GO:0061976) 1 0 .10 - < 0.01 1.00E00 1.00E00 perichondral bone morphogenesis (GO:0061974) 1 0 .10 - < 0.01 1.00E00 1.00E00 membrane bone morphogenesis (GO:0061973) 1 0 .10 - < 0.01 1.00E00 1.00E00 establishment of left/right asymmetry (GO:0061966) 3 0 .30 - < 0.01 1.00E00 1.00E00 rDNA heterochromatin assembly (GO:0000183) 7 0 .69 - < 0.01 1.00E00 1.00E00 penetration of cumulus oophorus (GO:0061956) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein K48-linked ubiquitination (GO:0061945) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of protein K48-linked ubiquitination (GO:0061944) 2 0 .20 - < 0.01 1.00E00 1.00E00 CD8-positive, alpha-beta T cell extravasation (GO:0035697) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitophagy by induced vacuole formation (GO:0035695) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to somatodendritic compartment (GO:0061938) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial protein catabolic process (GO:0035694) 6 0 .59 - < 0.01 1.00E00 1.00E00 T-helper 1 cell diapedesis (GO:0035688) 1 0 .10 - < 0.01 1.00E00 1.00E00 T-helper 1 cell extravasation (GO:0035687) 1 0 .10 - < 0.01 1.00E00 1.00E00 helper T cell diapedesis (GO:0035685) 3 0 .30 - < 0.01 1.00E00 1.00E00 helper T cell extravasation (GO:0035684) 4 0 .40 - < 0.01 1.00E00 1.00E00 peptidyl-lysine propionylation (GO:0061921) 1 0 .10 - < 0.01 1.00E00 1.00E00 manchette assembly (GO:1905198) 3 0 .30 - < 0.01 1.00E00 1.00E00 actin cortical patch assembly (GO:0000147) 1 0 .10 - < 0.01 1.00E00 1.00E00 posterior lateral line neuromast hair cell development (GO:0035677) 1 0 .10 - < 0.01 1.00E00 1.00E00 neuromast hair cell development (GO:0035675) 1 0 .10 - < 0.01 1.00E00 1.00E00 tricarboxylic acid transmembrane transport (GO:0035674) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of growth plate cartilage chondrocyte proliferation (GO:0061914) 1 0 .10 - < 0.01 1.00E00 1.00E00 autophagosome-endosome fusion (GO:0061910) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to morphine (GO:0043278) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 TRAM-dependent toll-like receptor 4 signaling pathway (GO:0035669) 3 0 .30 - < 0.01 1.00E00 1.00E00 TRAM-dependent toll-like receptor signaling pathway (GO:0035668) 3 0 .30 - < 0.01 1.00E00 1.00E00 TIRAP-dependent toll-like receptor 4 signaling pathway (GO:0035665) 1 0 .10 - < 0.01 1.00E00 1.00E00 TIRAP-dependent toll-like receptor signaling pathway (GO:0035664) 1 0 .10 - < 0.01 1.00E00 1.00E00 MyD88-dependent toll-like receptor 4 signaling pathway (GO:0035660) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac muscle tissue regeneration (GO:1905179) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle tissue regeneration (GO:1905178) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of vascular associated smooth muscle cell dedifferentiation (GO:1905176) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of vascular associated smooth muscle cell dedifferentiation (GO:1905174) 2 0 .20 - < 0.01 1.00E00 1.00E00 B cell costimulation (GO:0031296) 4 0 .40 - < 0.01 1.00E00 1.00E00 Ran protein signal transduction (GO:0031291) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of double-strand break repair via homologous recombination (GO:1905168) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 negative regulation of lysosomal protein catabolic process (GO:1905166) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of transcription involved in G2/M transition of mitotic cell cycle (GO:0000117) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of phagosome maturation (GO:1905162) 2 0 .20 - < 0.01 1.00E00 1.00E00 endosome to melanosome transport (GO:0035646) 10 0 .99 - < 0.01 1.00E00 1.00E00 enteric smooth muscle cell differentiation (GO:0035645) 1 0 .10 - < 0.01 1.00E00 1.00E00 phosphoanandamide dephosphorylation (GO:0035644) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of guanylate cyclase activity (GO:0031284) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of guanylate cyclase activity (GO:0031283) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of guanylate cyclase activity (GO:0031282) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of cyclase activity (GO:0031281) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 histidine biosynthetic process (GO:0000105) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of voltage-gated sodium channel activity (GO:1905152) 2 0 .20 - < 0.01 1.00E00 1.00E00 sulfate assimilation (GO:0000103) 3 0 .30 - < 0.01 1.00E00 1.00E00 FMN biosynthetic process (GO:0009398) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of voltage-gated sodium channel activity (GO:1905150) 7 0 .69 - < 0.01 1.00E00 1.00E00 folic acid-containing compound catabolic process (GO:0009397) 1 0 .10 - < 0.01 1.00E00 1.00E00 sulfur amino acid transport (GO:0000101) 6 0 .59 - < 0.01 1.00E00 1.00E00 proteasome assembly (GO:0043248) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 telomere maintenance in response to DNA damage (GO:0043247) 9 0 .89 - < 0.01 1.00E00 1.00E00 entry of bacterium into host cell (GO:0035635) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of pseudopodium assembly (GO:0031274) 9 0 .89 - < 0.01 1.00E00 1.00E00 regulation of pseudopodium assembly (GO:0031272) 9 0 .89 - < 0.01 1.00E00 1.00E00 pseudopodium retraction (GO:0031270) 1 0 .10 - < 0.01 1.00E00 1.00E00 translational attenuation (GO:0009386) 1 0 .10 - < 0.01 1.00E00 1.00E00 receptor transactivation (GO:0035624) 3 0 .30 - < 0.01 1.00E00 1.00E00 intrahepatic bile duct development (GO:0035622) 3 0 .30 - < 0.01 1.00E00 1.00E00 ER to Golgi ceramide transport (GO:0035621) 3 0 .30 - < 0.01 1.00E00 1.00E00 pseudopodium assembly (GO:0031269) 2 0 .20 - < 0.01 1.00E00 1.00E00 pseudopodium organization (GO:0031268) 4 0 .40 - < 0.01 1.00E00 1.00E00 biotin import across plasma membrane (GO:1905135) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of meiotic chromosome separation (GO:1905133) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of meiotic chromosome separation (GO:1905132) 2 0 .20 - < 0.01 1.00E00 1.00E00 histone H2B conserved C-terminal lysine deubiquitination (GO:0035616) 4 0 .40 - < 0.01 1.00E00 1.00E00 protein branching point deglutamylation (GO:0035611) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein side chain deglutamylation (GO:0035610) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of axo-dendritic protein transport (GO:1905128) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of axo-dendritic protein transport (GO:1905126) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of glucosylceramidase activity (GO:1905123) 2 0 .20 - < 0.01 1.00E00 1.00E00 C-terminal protein deglutamylation (GO:0035609) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein deglutamylation (GO:0035608) 4 0 .40 - < 0.01 1.00E00 1.00E00 tRNA methylthiolation (GO:0035600) 1 0 .10 - < 0.01 1.00E00 1.00E00 actin rod assembly (GO:0031247) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore (GO:1905116) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of lateral attachment of mitotic spindle microtubules to kinetochore (GO:1905115) 1 0 .10 - < 0.01 1.00E00 1.00E00 tRNA transcription by RNA polymerase III (GO:0042797) 1 0 .10 - < 0.01 1.00E00 1.00E00 snRNA transcription by RNA polymerase III (GO:0042796) 8 0 .79 - < 0.01 1.00E00 1.00E00 snRNA transcription by RNA polymerase II (GO:0042795) 9 0 .89 - < 0.01 1.00E00 1.00E00 5S class rRNA transcription by RNA polymerase III (GO:0042791) 1 0 .10 - < 0.01 1.00E00 1.00E00 nucleolar large rRNA transcription by RNA polymerase I (GO:0042790) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein biotinylation (GO:0009305) 1 0 .10 - < 0.01 1.00E00 1.00E00 tRNA transcription (GO:0009304) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of vascular associated smooth muscle contraction (GO:1904695) 2 0 .20 - < 0.01 1.00E00 1.00E00 rRNA transcription (GO:0009303) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 negative regulation of vascular associated smooth muscle contraction (GO:1904694) 3 0 .30 - < 0.01 1.00E00 1.00E00 midbrain morphogenesis (GO:1904693) 1 0 .10 - < 0.01 1.00E00 1.00E00 snRNA transcription (GO:0009301) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 positive regulation of type B pancreatic cell proliferation (GO:1904692) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cytoplasmic translational initiation (GO:1904690) 3 0 .30 - < 0.01 1.00E00 1.00E00 tRNA 3'-end processing (GO:0042780) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of developmental pigmentation (GO:0048086) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cytoplasmic translational initiation (GO:1904689) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cytoplasmic translational initiation (GO:1904688) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of metalloendopeptidase activity (GO:1904685) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to 3-methylcholanthrene (GO:1904682) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to 3-methylcholanthrene (GO:1904681) 1 0 .10 - < 0.01 1.00E00 1.00E00 tRNA 3'-trailer cleavage (GO:0042779) 3 0 .30 - < 0.01 1.00E00 1.00E00 DNA damage response, signal transduction resulting in transcription (GO:0042772) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 negative regulation of eye pigmentation (GO:0048074) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of somatic stem cell division (GO:1904677) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of somatic stem cell division (GO:1904675) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of somatic stem cell population maintenance (GO:1904674) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of somatic stem cell population maintenance (GO:1904673) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of somatic stem cell population maintenance (GO:1904672) 6 0 .59 - < 0.01 1.00E00 1.00E00 DNA damage response, detection of DNA damage (GO:0042769) 6 0 .59 - < 0.01 1.00E00 1.00E00 nucleosome mobilization (GO:0042766) 3 0 .30 - < 0.01 1.00E00 1.00E00 eye pigmentation (GO:0048069) 3 0 .30 - < 0.01 1.00E00 1.00E00 male germ-line stem cell population maintenance (GO:0036098) 1 0 .10 - < 0.01 1.00E00 1.00E00 ATP export (GO:1904669) 2 0 .20 - < 0.01 1.00E00 1.00E00 germ cell proliferation (GO:0036093) 2 0 .20 - < 0.01 1.00E00 1.00E00 phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of ubiquitin protein ligase activity (GO:1904667) 9 0 .89 - < 0.01 1.00E00 1.00E00 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0036091) 4 0 .40 - < 0.01 1.00E00 1.00E00 cleavage furrow ingression (GO:0036090) 2 0 .20 - < 0.01 1.00E00 1.00E00 long-chain fatty acid catabolic process (GO:0042758) 5 0 .49 - < 0.01 1.00E00 1.00E00 post-embryonic eye morphogenesis (GO:0048050) 5 0 .49 - < 0.01 1.00E00 1.00E00 GDP-fucose import into Golgi lumen (GO:0036085) 1 0 .10 - < 0.01 1.00E00 1.00E00 circadian sleep/wake cycle, non-REM sleep (GO:0042748) 1 0 .10 - < 0.01 1.00E00 1.00E00 circadian sleep/wake cycle (GO:0042745) 3 0 .30 - < 0.01 1.00E00 1.00E00 mating behavior, sex discrimination (GO:0048047) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of fat cell apoptotic process (GO:1904649) 1 0 .10 - < 0.01 1.00E00 1.00E00 direct ossification (GO:0036072) 6 0 .59 - < 0.01 1.00E00 1.00E00 N-glycan fucosylation (GO:0036071) 1 0 .10 - < 0.01 1.00E00 1.00E00 exogenous drug catabolic process (GO:0042738) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 drug catabolic process (GO:0042737) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 D-xylose metabolic process (GO:0042732) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of CD4-positive, alpha-beta T cell costimulation (GO:1900281) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of CD4-positive, alpha-beta T cell costimulation (GO:1900280) 1 0 .10 - < 0.01 1.00E00 1.00E00 heme O biosynthetic process (GO:0048034) 1 0 .10 - < 0.01 1.00E00 1.00E00 heme o metabolic process (GO:0048033) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein O-linked fucosylation (GO:0036066) 4 0 .40 - < 0.01 1.00E00 1.00E00 cellular response to ionomycin (GO:1904637) 5 0 .49 - < 0.01 1.00E00 1.00E00 response to ionomycin (GO:1904636) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of glomerular visceral epithelial cell apoptotic process (GO:1904635) 2 0 .20 - < 0.01 1.00E00 1.00E00 slit diaphragm assembly (GO:0036060) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of glomerular visceral epithelial cell apoptotic process (GO:1904633) 2 0 .20 - < 0.01 1.00E00 1.00E00 farnesol catabolic process (GO:0016488) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to glucoside (GO:1904632) 1 0 .10 - < 0.01 1.00E00 1.00E00 farnesol metabolic process (GO:0016487) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to glucoside (GO:1904631) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of CD4-positive, alpha-beta T cell costimulation (GO:1900279) 2 0 .20 - < 0.01 1.00E00 1.00E00 peptide hormone processing (GO:0016486) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 cellular response to diterpene (GO:1904630) 1 0 .10 - < 0.01 1.00E00 1.00E00 flavin-containing compound catabolic process (GO:0042728) 1 0 .10 - < 0.01 1.00E00 1.00E00 flavin-containing compound biosynthetic process (GO:0042727) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of proteinase activated receptor activity (GO:1900276) 1 0 .10 - < 0.01 1.00E00 1.00E00 flavin-containing compound metabolic process (GO:0042726) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of phospholipase C activity (GO:1900275) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of transcription by RNA polymerase III (GO:0016480) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of mRNA splicing, via spliceosome (GO:0048026) 23 0 2.27 - < 0.01 2.61E-01 1.00E00 negative regulation of mRNA splicing, via spliceosome (GO:0048025) 23 0 2.27 - < 0.01 2.61E-01 1.00E00 positive regulation of melanin biosynthetic process (GO:0048023) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of melanin biosynthetic process (GO:0048022) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of melanin biosynthetic process (GO:0048021) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 filtration diaphragm assembly (GO:0036058) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to diterpene (GO:1904629) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of transcription by RNA polymerase I (GO:0016479) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of DNA-directed DNA polymerase activity (GO:1900264) 10 0 .99 - < 0.01 1.00E00 1.00E00 sperm ejaculation (GO:0042713) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of DNA-directed DNA polymerase activity (GO:1900262) 10 0 .99 - < 0.01 1.00E00 1.00E00 maternal behavior (GO:0042711) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 negative regulation of RNA-directed 5'-3' RNA polymerase activity (GO:1900260) 1 0 .10 - < 0.01 1.00E00 1.00E00 inositol phosphate-mediated signaling (GO:0048016) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 ephrin receptor signaling pathway (GO:0048013) 26 0 2.57 - < 0.01 1.65E-01 1.00E00 neurotrophin TRK receptor signaling pathway (GO:0048011) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 peptidyl-lysine desuccinylation (GO:0036049) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein desuccinylation (GO:0036048) 2 0 .20 - < 0.01 1.00E00 1.00E00 peptidyl-lysine demalonylation (GO:0036047) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein demalonylation (GO:0036046) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of actin binding (GO:1904618) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of actin binding (GO:1904617) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of actin binding (GO:1904616) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular response to 2,3,7,8-tetrachlorodibenzodioxine (GO:1904613) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to 2,3,7,8-tetrachlorodibenzodioxine (GO:1904612) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of RNA-directed 5'-3' RNA polymerase activity (GO:1900259) 1 0 .10 - < 0.01 1.00E00 1.00E00 eye photoreceptor cell fate commitment (GO:0042706) 2 0 .20 - < 0.01 1.00E00 1.00E00 antigen processing and presentation, exogenous lipid antigen via MHC class Ib (GO:0048007) 4 0 .40 - < 0.01 1.00E00 1.00E00 luteinizing hormone signaling pathway (GO:0042700) 1 0 .10 - < 0.01 1.00E00 1.00E00 antigen processing and presentation, endogenous lipid antigen via MHC class Ib (GO:0048006) 2 0 .20 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of lipid antigen via MHC class Ib (GO:0048003) 4 0 .40 - < 0.01 1.00E00 1.00E00 osteoclast development (GO:0036035) 6 0 .59 - < 0.01 1.00E00 1.00E00 cellular response to monosodium L-glutamate (GO:1904609) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to monosodium L-glutamate (GO:1904608) 1 0 .10 - < 0.01 1.00E00 1.00E00 neural crest cell delamination (GO:0036032) 1 0 .10 - < 0.01 1.00E00 1.00E00 recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex (GO:0036031) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of advanced glycation end-product receptor activity (GO:1904605) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of advanced glycation end-product receptor activity (GO:1904604) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of advanced glycation end-product receptor activity (GO:1904603) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of RIG-I signaling pathway (GO:1900246) 10 0 .99 - < 0.01 1.00E00 1.00E00 positive regulation of MDA-5 signaling pathway (GO:1900245) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of synaptic vesicle endocytosis (GO:1900243) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of phenotypic switching (GO:1900240) 2 0 .20 - < 0.01 1.00E00 1.00E00 embryonic skeletal limb joint morphogenesis (GO:0036023) 1 0 .10 - < 0.01 1.00E00 1.00E00 limb joint morphogenesis (GO:0036022) 2 0 .20 - < 0.01 1.00E00 1.00E00 somatic recombination of immunoglobulin gene segments (GO:0016447) 26 0 2.57 - < 0.01 1.65E-01 1.00E00 somatic hypermutation of immunoglobulin genes (GO:0016446) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 regulation of phenotypic switching (GO:1900239) 2 0 .20 - < 0.01 1.00E00 1.00E00 somatic diversification of immunoglobulins (GO:0016445) 32 0 3.16 - < 0.01 1.12E-01 9.20E-01 regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway (GO:1900238) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of Kit signaling pathway (GO:1900235) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of Kit signaling pathway (GO:1900234) 2 0 .20 - < 0.01 1.00E00 1.00E00 P granule organization (GO:0030719) 2 0 .20 - < 0.01 1.00E00 1.00E00 germ-line stem cell population maintenance (GO:0030718) 4 0 .40 - < 0.01 1.00E00 1.00E00 cellular response to erythropoietin (GO:0036018) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to erythropoietin (GO:0036017) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-3 (GO:0036016) 5 0 .49 - < 0.01 1.00E00 1.00E00 response to interleukin-3 (GO:0036015) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of mini excitatory postsynaptic potential (GO:0061886) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry (GO:1900224) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of anterograde axonal transport of mitochondrion (GO:0061881) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of amyloid-beta clearance (GO:1900222) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of anterograde axonal transport of mitochondrion (GO:0061880) 1 0 .10 - < 0.01 1.00E00 1.00E00 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis (GO:1900220) 2 0 .20 - < 0.01 1.00E00 1.00E00 vitelline membrane formation (GO:0030704) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of apoptotic process involved in metanephric nephron tubule development (GO:1900218) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of apoptotic process involved in metanephric nephron tubule development (GO:1900217) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of hepatic stellate cell contraction (GO:0061875) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of hepatic stellate cell contraction (GO:0061874) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of hepatic stellate cell contraction (GO:0061873) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of apoptotic process involved in metanephric collecting duct development (GO:1900215) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of apoptotic process involved in metanephric collecting duct development (GO:1900214) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of hepatic stellate cell migration (GO:0061871) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of hepatic stellate cell migration (GO:0061870) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal cell apoptotic process involved in metanephros development (GO:1900212) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal cell apoptotic process involved in metanephros development (GO:1900211) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cardiolipin metabolic process (GO:1900210) 2 0 .20 - < 0.01 1.00E00 1.00E00 sulfur amino acid catabolic process (GO:0000098) 6 0 .59 - < 0.01 1.00E00 1.00E00 sulfur amino acid biosynthetic process (GO:0000097) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 regulation of hepatic stellate cell migration (GO:0061869) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of cardiolipin metabolic process (GO:1900208) 4 0 .40 - < 0.01 1.00E00 1.00E00 mitotic metaphase (GO:0000089) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitotic M phase (GO:0000087) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitotic G2 phase (GO:0000085) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitotic G1 phase (GO:0000080) 1 0 .10 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum stress-induced pre-emptive quality control (GO:0061857) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to cholecystokinin (GO:0061847) 3 0 .30 - < 0.01 1.00E00 1.00E00 neuropeptide processing (GO:0061837) 1 0 .10 - < 0.01 1.00E00 1.00E00 purinergic nucleotide receptor signaling pathway (GO:0035590) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 protein localization to tricellular tight junction (GO:0061833) 3 0 .30 - < 0.01 1.00E00 1.00E00 ribosomal small subunit export from nucleus (GO:0000056) 7 0 .69 - < 0.01 1.00E00 1.00E00 ribosomal large subunit export from nucleus (GO:0000055) 7 0 .69 - < 0.01 1.00E00 1.00E00 ribosomal subunit export from nucleus (GO:0000054) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 argininosuccinate metabolic process (GO:0000053) 2 0 .20 - < 0.01 1.00E00 1.00E00 citrulline metabolic process (GO:0000052) 6 0 .59 - < 0.01 1.00E00 1.00E00 urea cycle (GO:0000050) 7 0 .69 - < 0.01 1.00E00 1.00E00 G protein-coupled purinergic nucleotide receptor signaling pathway (GO:0035589) 1 0 .10 - < 0.01 1.00E00 1.00E00 G protein-coupled purinergic receptor signaling pathway (GO:0035588) 9 0 .89 - < 0.01 1.00E00 1.00E00 sequestering of TGFbeta in extracellular matrix (GO:0035583) 4 0 .40 - < 0.01 1.00E00 1.00E00 sequestering of BMP in extracellular matrix (GO:0035582) 3 0 .30 - < 0.01 1.00E00 1.00E00 telomeric D-loop disassembly (GO:0061820) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of guanyl-nucleotide exchange factor activity (GO:1905099) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization (GO:1905090) 1 0 .10 - < 0.01 1.00E00 1.00E00 telomeric DNA-containing double minutes formation (GO:0061819) 4 0 .40 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum-plasma membrane tethering (GO:0061817) 6 0 .59 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-serine trimethylation (GO:0035573) 1 0 .10 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-serine dimethylation (GO:0035572) 1 0 .10 - < 0.01 1.00E00 1.00E00 vacuolar sequestering (GO:0043181) 1 0 .10 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-serine methylation (GO:0035570) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization (GO:1905089) 1 0 .10 - < 0.01 1.00E00 1.00E00 electron transport coupled proton transport (GO:0015990) 5 0 .49 - < 0.01 1.00E00 1.00E00 cell wall mannoprotein biosynthetic process (GO:0000032) 1 0 .10 - < 0.01 1.00E00 1.00E00 rhythmic excitation (GO:0043179) 1 0 .10 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-proline methylation (GO:0035568) 1 0 .10 - < 0.01 1.00E00 1.00E00 nucleoside salvage (GO:0043174) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of chromatin binding (GO:0035563) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 negative regulation of chromatin binding (GO:0035562) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of chromatin binding (GO:0035561) 22 0 2.18 - < 0.01 2.56E-01 1.00E00 energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) 5 0 .49 - < 0.01 1.00E00 1.00E00 ribosomal small subunit assembly (GO:0000028) 19 0 1.88 - < 0.01 4.08E-01 1.00E00 ribosomal large subunit assembly (GO:0000027) 26 0 2.57 - < 0.01 1.65E-01 1.00E00 positive regulation of tight junction disassembly (GO:1905075) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of tight junction disassembly (GO:1905073) 2 0 .20 - < 0.01 1.00E00 1.00E00 cardiac jelly development (GO:1905072) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitotic spindle elongation (GO:0000022) 6 0 .59 - < 0.01 1.00E00 1.00E00 cell envelope organization (GO:0043163) 1 0 .10 - < 0.01 1.00E00 1.00E00 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 oxidative single-stranded RNA demethylation (GO:0035553) 3 0 .30 - < 0.01 1.00E00 1.00E00 oxidative single-stranded DNA demethylation (GO:0035552) 3 0 .30 - < 0.01 1.00E00 1.00E00 photosynthesis (GO:0015979) 1 0 .10 - < 0.01 1.00E00 1.00E00 allantois development (GO:1905069) 3 0 .30 - < 0.01 1.00E00 1.00E00 L-proline biosynthetic process (GO:0055129) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of canonical Wnt signaling pathway involved in heart development (GO:1905068) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mitotic recombination (GO:0000019) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of canonical Wnt signaling pathway involved in heart development (GO:1905067) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of canonical Wnt signaling pathway involved in heart development (GO:1905066) 2 0 .20 - < 0.01 1.00E00 1.00E00 alpha-glucoside transport (GO:0000017) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of vascular associated smooth muscle cell differentiation (GO:1905065) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of vascular associated smooth muscle cell differentiation (GO:1905064) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of vascular associated smooth muscle cell differentiation (GO:1905063) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 positive regulation of cardioblast proliferation (GO:1905062) 1 0 .10 - < 0.01 1.00E00 1.00E00 single strand break repair (GO:0000012) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 determination of left/right asymmetry in nervous system (GO:0035545) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of SNARE complex assembly (GO:0035544) 2 0 .20 - < 0.01 1.00E00 1.00E00 induction of bacterial agglutination (GO:0043152) 1 0 .10 - < 0.01 1.00E00 1.00E00 diadenosine tetraphosphate biosynthetic process (GO:0015966) 3 0 .30 - < 0.01 1.00E00 1.00E00 diadenosine tetraphosphate metabolic process (GO:0015965) 3 0 .30 - < 0.01 1.00E00 1.00E00 diadenosine triphosphate catabolic process (GO:0015964) 1 0 .10 - < 0.01 1.00E00 1.00E00 diadenosine triphosphate metabolic process (GO:0015962) 1 0 .10 - < 0.01 1.00E00 1.00E00 diadenosine polyphosphate catabolic process (GO:0015961) 5 0 .49 - < 0.01 1.00E00 1.00E00 diadenosine polyphosphate biosynthetic process (GO:0015960) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of base-excision repair (GO:1905053) 2 0 .20 - < 0.01 1.00E00 1.00E00 epiboly involved in gastrulation with mouth forming second (GO:0055113) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of base-excision repair (GO:1905051) 2 0 .20 - < 0.01 1.00E00 1.00E00 GDP-mannose biosynthetic process (GO:0009298) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of metallopeptidase activity (GO:1905050) 5 0 .49 - < 0.01 1.00E00 1.00E00 sno(s)RNA processing (GO:0043144) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 peptide modification (GO:0031179) 2 0 .20 - < 0.01 1.00E00 1.00E00 diadenosine polyphosphate metabolic process (GO:0015959) 8 0 .79 - < 0.01 1.00E00 1.00E00 Golgi to transport vesicle transport (GO:0055108) 2 0 .20 - < 0.01 1.00E00 1.00E00 Golgi to secretory granule transport (GO:0055107) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of Schwann cell proliferation involved in axon regeneration (GO:1905045) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of Schwann cell proliferation involved in axon regeneration (GO:1905044) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of epithelium regeneration (GO:1905043) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of epithelium regeneration (GO:1905042) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of epithelium regeneration (GO:1905041) 2 0 .20 - < 0.01 1.00E00 1.00E00 DNA replication, removal of RNA primer (GO:0043137) 4 0 .40 - < 0.01 1.00E00 1.00E00 retrograde transport, plasma membrane to Golgi (GO:0035526) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of hindgut contraction (GO:0043134) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein K29-linked deubiquitination (GO:0035523) 4 0 .40 - < 0.01 1.00E00 1.00E00 monoubiquitinated histone H2A deubiquitination (GO:0035522) 4 0 .40 - < 0.01 1.00E00 1.00E00 monoubiquitinated histone deubiquitination (GO:0035521) 4 0 .40 - < 0.01 1.00E00 1.00E00 monoubiquitinated protein deubiquitination (GO:0035520) 9 0 .89 - < 0.01 1.00E00 1.00E00 rRNA methylation (GO:0031167) 20 0 1.98 - < 0.01 2.51E-01 1.00E00 phosphatidylinositol catabolic process (GO:0031161) 3 0 .30 - < 0.01 1.00E00 1.00E00 formate metabolic process (GO:0015942) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of antifungal innate immune response (GO:1905035) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of membrane repolarization during cardiac muscle cell action potential (GO:1905033) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of membrane repolarization during cardiac muscle cell action potential (GO:1905032) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of membrane repolarization during cardiac muscle cell action potential (GO:1905031) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of 1-phosphatidylinositol 4-kinase activity (GO:0043128) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein K29-linked ubiquitination (GO:0035519) 4 0 .40 - < 0.01 1.00E00 1.00E00 histone H2A monoubiquitination (GO:0035518) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 regulation of 1-phosphatidylinositol 4-kinase activity (GO:0043126) 1 0 .10 - < 0.01 1.00E00 1.00E00 oxidative RNA demethylation (GO:0035513) 5 0 .49 - < 0.01 1.00E00 1.00E00 oxidative DNA demethylation (GO:0035511) 7 0 .69 - < 0.01 1.00E00 1.00E00 DNA dealkylation (GO:0035510) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 coenzyme A catabolic process (GO:0015938) 1 0 .10 - < 0.01 1.00E00 1.00E00 coenzyme A biosynthetic process (GO:0015937) 10 0 .99 - < 0.01 1.00E00 1.00E00 coenzyme A metabolic process (GO:0015936) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential (GO:1905026) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential (GO:1905025) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of membrane repolarization during ventricular cardiac muscle cell action potential (GO:1905024) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of threonine-tRNA ligase activity (GO:1905023) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of threonine-tRNA ligase activity (GO:1905021) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of methionine-tRNA ligase activity (GO:1905020) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of myosin-light-chain-phosphatase activity (GO:0035509) 6 0 .59 - < 0.01 1.00E00 1.00E00 2'-deoxyribonucleotide biosynthetic process (GO:0009265) 10 0 .99 - < 0.01 1.00E00 1.00E00 positive regulation of myosin-light-chain-phosphatase activity (GO:0035508) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of myosin-light-chain-phosphatase activity (GO:0035507) 8 0 .79 - < 0.01 1.00E00 1.00E00 deoxyribonucleotide biosynthetic process (GO:0009263) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 replication fork arrest (GO:0043111) 3 0 .30 - < 0.01 1.00E00 1.00E00 metanephric part of ureteric bud development (GO:0035502) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of methionine-tRNA ligase activity (GO:1905018) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of isoleucine-tRNA ligase activity (GO:1905017) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of isoleucine-tRNA ligase activity (GO:1905015) 1 0 .10 - < 0.01 1.00E00 1.00E00 10-formyltetrahydrofolate catabolic process (GO:0009258) 1 0 .10 - < 0.01 1.00E00 1.00E00 10-formyltetrahydrofolate biosynthetic process (GO:0009257) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of L-lysine import across plasma membrane (GO:1905010) 1 0 .10 - < 0.01 1.00E00 1.00E00 10-formyltetrahydrofolate metabolic process (GO:0009256) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of GTP cyclohydrolase I activity (GO:0043105) 1 0 .10 - < 0.01 1.00E00 1.00E00 glucan catabolic process (GO:0009251) 9 0 .89 - < 0.01 1.00E00 1.00E00 hypoxanthine salvage (GO:0043103) 2 0 .20 - < 0.01 1.00E00 1.00E00 amino acid salvage (GO:0043102) 5 0 .49 - < 0.01 1.00E00 1.00E00 aminophospholipid transport (GO:0015917) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of L-lysine import across plasma membrane (GO:1905008) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation (GO:1905006) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein lipoylation (GO:0009249) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of membrane repolarization during atrial cardiac muscle cell action potential (GO:1905000) 1 0 .10 - < 0.01 1.00E00 1.00E00 isopentenyl diphosphate biosynthetic process (GO:0009240) 5 0 .49 - < 0.01 1.00E00 1.00E00 sno(s)RNA 3'-end processing (GO:0031126) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 rRNA 3'-end processing (GO:0031125) 10 0 .99 - < 0.01 1.00E00 1.00E00 snRNA pseudouridine synthesis (GO:0031120) 3 0 .30 - < 0.01 1.00E00 1.00E00 siderophore metabolic process (GO:0009237) 1 0 .10 - < 0.01 1.00E00 1.00E00 cobalamin metabolic process (GO:0009235) 6 0 .59 - < 0.01 1.00E00 1.00E00 menaquinone biosynthetic process (GO:0009234) 1 0 .10 - < 0.01 1.00E00 1.00E00 menaquinone metabolic process (GO:0009233) 1 0 .10 - < 0.01 1.00E00 1.00E00 riboflavin biosynthetic process (GO:0009231) 1 0 .10 - < 0.01 1.00E00 1.00E00 tRNA pseudouridine synthesis (GO:0031119) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of microtubule depolymerization (GO:0031117) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of microtubule depolymerization (GO:0031114) 33 0 3.26 - < 0.01 6.95E-02 7.22E-01 thiamine diphosphate biosynthetic process (GO:0009229) 1 0 .10 - < 0.01 1.00E00 1.00E00 nucleotide-sugar catabolic process (GO:0009227) 2 0 .20 - < 0.01 1.00E00 1.00E00 nucleotide-sugar biosynthetic process (GO:0009226) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 pyrimidine deoxyribonucleotide catabolic process (GO:0009223) 8 0 .79 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleotide catabolic process (GO:0009222) 5 0 .49 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleotide biosynthetic process (GO:0009221) 8 0 .79 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleotide biosynthetic process (GO:0009220) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 septin ring organization (GO:0031106) 2 0 .20 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleotide metabolic process (GO:0009219) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 pyrimidine ribonucleotide metabolic process (GO:0009218) 19 0 1.88 - < 0.01 4.08E-01 1.00E00 purine deoxyribonucleoside triphosphate catabolic process (GO:0009217) 4 0 .40 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleoside triphosphate biosynthetic process (GO:0009216) 2 0 .20 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 cyclic nucleotide catabolic process (GO:0009214) 5 0 .49 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside triphosphate catabolic process (GO:0009213) 2 0 .20 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside triphosphate biosynthetic process (GO:0009212) 3 0 .30 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside triphosphate metabolic process (GO:0009211) 5 0 .49 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside triphosphate catabolic process (GO:0009210) 1 0 .10 - < 0.01 1.00E00 1.00E00 follicle-stimulating hormone signaling pathway (GO:0042699) 4 0 .40 - < 0.01 1.00E00 1.00E00 menarche (GO:0042696) 1 0 .10 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) 9 0 .89 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 purine ribonucleoside triphosphate catabolic process (GO:0009207) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of connective tissue replacement involved in inflammatory response wound healing (GO:1904597) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of connective tissue replacement involved in inflammatory response wound healing (GO:1904596) 2 0 .20 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside triphosphate catabolic process (GO:0009204) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of termination of RNA polymerase II transcription (GO:1904595) 1 0 .10 - < 0.01 1.00E00 1.00E00 ribonucleoside triphosphate catabolic process (GO:0009203) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of termination of RNA polymerase II transcription (GO:1904594) 3 0 .30 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside triphosphate biosynthetic process (GO:0009202) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of protein refolding (GO:1904592) 1 0 .10 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside triphosphate metabolic process (GO:0009200) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 regulation of cardioblast cell fate specification (GO:0042686) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to glycoprotein (GO:1904588) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to glycoprotein (GO:1904587) 7 0 .69 - < 0.01 1.00E00 1.00E00 cellular response to putrescine (GO:1904586) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to putrescine (GO:1904585) 1 0 .10 - < 0.01 1.00E00 1.00E00 retinal cone cell differentiation (GO:0042670) 8 0 .79 - < 0.01 1.00E00 1.00E00 cellular response to thapsigargin (GO:1904579) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to thapsigargin (GO:1904578) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of selenocysteine insertion sequence binding (GO:1904574) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of selenocysteine insertion sequence binding (GO:1904573) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of mRNA binding (GO:1904572) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of selenocysteine incorporation (GO:1904571) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of selenocysteine incorporation (GO:1904570) 1 0 .10 - < 0.01 1.00E00 1.00E00 auditory receptor cell fate determination (GO:0042668) 1 0 .10 - < 0.01 1.00E00 1.00E00 auditory receptor cell fate specification (GO:0042667) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of ectodermal cell fate specification (GO:0042666) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of ectodermal cell fate specification (GO:0042665) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of endodermal cell fate specification (GO:0042664) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of endodermal cell fate specification (GO:0042663) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of mesodermal cell fate specification (GO:0042662) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of mesodermal cell fate specification (GO:0042661) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of selenocysteine incorporation (GO:1904569) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein localization to postsynapse (GO:0062237) 31 0 3.07 - < 0.01 1.09E-01 9.06E-01 cellular response to wortmannin (GO:1904568) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to wortmannin (GO:1904567) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to 1-oleoyl-sn-glycerol 3-phosphate (GO:1904566) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to 1-oleoyl-sn-glycerol 3-phosphate (GO:1904565) 1 0 .10 - < 0.01 1.00E00 1.00E00 prostanoid catabolic process (GO:0062232) 2 0 .20 - < 0.01 1.00E00 1.00E00 phosphatidylinositol 5-phosphate metabolic process (GO:1904562) 2 0 .20 - < 0.01 1.00E00 1.00E00 mitigation of host defenses by symbiont (GO:0030682) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to arachidonic acid (GO:1904550) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of oocyte maturation (GO:1900195) 2 0 .20 - < 0.01 1.00E00 1.00E00 membrane bending (GO:0097753) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of oocyte maturation (GO:1900194) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of oocyte maturation (GO:1900193) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of DNA stability (GO:0097752) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of clathrin-dependent endocytosis (GO:1900186) 5 0 .49 - < 0.01 1.00E00 1.00E00 mitochondrial tRNA 5'-end processing (GO:0097745) 2 0 .20 - < 0.01 1.00E00 1.00E00 urate salt excretion (GO:0097744) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of hair cycle (GO:0042635) 2 0 .20 - < 0.01 1.00E00 1.00E00 de novo centriole assembly (GO:0097742) 5 0 .49 - < 0.01 1.00E00 1.00E00 cellular response to water deprivation (GO:0042631) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of telomeric loop disassembly (GO:1904535) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of telomeric loop disassembly (GO:1904534) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of telomeric loop disassembly (GO:1904533) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of actin filament binding (GO:1904531) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of actin filament binding (GO:1904530) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry (GO:1900176) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry (GO:1900175) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of glucocorticoid mediated signaling pathway (GO:1900170) 2 0 .20 - < 0.01 1.00E00 1.00E00 beta-lactam antibiotic metabolic process (GO:0030653) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of actin filament binding (GO:1904529) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of microtubule binding (GO:1904528) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of microtubule binding (GO:1904527) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of microtubule binding (GO:1904526) 10 0 .99 - < 0.01 1.00E00 1.00E00 nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry (GO:1900164) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of phospholipid scramblase activity (GO:1900163) 1 0 .10 - < 0.01 1.00E00 1.00E00 calcineurin-mediated signaling (GO:0097720) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 regulation of phospholipid scramblase activity (GO:1900161) 1 0 .10 - < 0.01 1.00E00 1.00E00 aminoglycoside antibiotic metabolic process (GO:0030647) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of TORC2 signaling (GO:1904515) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of bone mineralization involved in bone maturation (GO:1900159) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of bone trabecula formation (GO:1900155) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of bone trabecula formation (GO:1900154) 2 0 .20 - < 0.01 1.00E00 1.00E00 vesicle targeting, trans-Golgi to periciliary membrane compartment (GO:0097712) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900152) 3 0 .30 - < 0.01 1.00E00 1.00E00 ciliary basal body-plasma membrane docking (GO:0097711) 1 0 .10 - < 0.01 1.00E00 1.00E00 polyketide metabolic process (GO:0030638) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of telomere maintenance in response to DNA damage (GO:1904506) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of telomere maintenance in response to DNA damage (GO:1904505) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of nodal signaling pathway involved in determination of left/right asymmetry (GO:1900146) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of nodal signaling pathway involved in determination of left/right asymmetry (GO:1900145) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of oligodendrocyte apoptotic process (GO:1900143) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of arachidonic acid secretion (GO:1900139) 3 0 .30 - < 0.01 1.00E00 1.00E00 meiotic chromosome movement towards spindle pole (GO:0016344) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of renin secretion into blood stream (GO:1900135) 1 0 .10 - < 0.01 1.00E00 1.00E00 secretory granule maturation (GO:0061792) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of renin secretion into blood stream (GO:1900134) 1 0 .10 - < 0.01 1.00E00 1.00E00 calcium-dependent cell-matrix adhesion (GO:0016340) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of renin secretion into blood stream (GO:1900133) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of lipid binding (GO:1900131) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of lipid binding (GO:1900130) 1 0 .10 - < 0.01 1.00E00 1.00E00 dense core granule priming (GO:0061789) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of G-protein activated inward rectifier potassium channel activity (GO:1900128) 1 0 .10 - < 0.01 1.00E00 1.00E00 establishment or maintenance of polarity of follicular epithelium (GO:0016334) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of hyaluronan biosynthetic process (GO:1900127) 5 0 .49 - < 0.01 1.00E00 1.00E00 morphogenesis of follicular epithelium (GO:0016333) 1 0 .10 - < 0.01 1.00E00 1.00E00 establishment or maintenance of polarity of embryonic epithelium (GO:0016332) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of nodal receptor complex assembly (GO:1900124) 1 0 .10 - < 0.01 1.00E00 1.00E00 vesicle fusion with vesicle (GO:0061782) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of nodal receptor complex assembly (GO:1900123) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of DNA repair by transcription from RNA polymerase II promoter (GO:0100026) 2 0 .20 - < 0.01 1.00E00 1.00E00 female meiosis chromosome segregation (GO:0016321) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of histone H3-K9 trimethylation (GO:1900114) 3 0 .30 - < 0.01 1.00E00 1.00E00 xenobiotic transport across blood-nerve barrier (GO:0061772) 1 0 .10 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum membrane fusion (GO:0016320) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of histone H3-K9 trimethylation (GO:1900113) 7 0 .69 - < 0.01 1.00E00 1.00E00 response to caloric restriction (GO:0061771) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of histone H3-K9 trimethylation (GO:1900112) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 negative regulation of histone H3-K9 dimethylation (GO:1900110) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of histone H3-K9 dimethylation (GO:1900109) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of lung blood pressure (GO:0061767) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of nodal signaling pathway (GO:1900108) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of nodal signaling pathway (GO:1900107) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of heart induction by canonical Wnt signaling pathway (GO:0100012) 1 0 .10 - < 0.01 1.00E00 1.00E00 multivesicular body-lysosome fusion (GO:0061763) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of endoplasmic reticulum unfolded protein response (GO:1900102) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 leukocyte adhesion to arterial endothelial cell (GO:0061757) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle contraction by action potential (GO:0100001) 1 0 .10 - < 0.01 1.00E00 1.00E00 substrate localization to autophagosome (GO:0061753) 1 0 .10 - < 0.01 1.00E00 1.00E00 motor learning (GO:0061743) 6 0 .59 - < 0.01 1.00E00 1.00E00 manganese ion homeostasis (GO:0055071) 3 0 .30 - < 0.01 1.00E00 1.00E00 carnosine biosynthetic process (GO:0035499) 1 0 .10 - < 0.01 1.00E00 1.00E00 carnosine metabolic process (GO:0035498) 2 0 .20 - < 0.01 1.00E00 1.00E00 late endosomal microautophagy (GO:0061738) 3 0 .30 - < 0.01 1.00E00 1.00E00 SNARE complex disassembly (GO:0035494) 3 0 .30 - < 0.01 1.00E00 1.00E00 engulfment of target by autophagosome (GO:0061736) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of leukotriene production involved in inflammatory response (GO:0035491) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of leukotriene production involved in inflammatory response (GO:0035490) 1 0 .10 - < 0.01 1.00E00 1.00E00 parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization (GO:0061734) 4 0 .40 - < 0.01 1.00E00 1.00E00 mitochondrial acetyl-CoA biosynthetic process from pyruvate (GO:0061732) 7 0 .69 - < 0.01 1.00E00 1.00E00 purine nucleobase salvage (GO:0043096) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of GTP cyclohydrolase I activity (GO:0043095) 1 0 .10 - < 0.01 1.00E00 1.00E00 methylglyoxal catabolic process to lactate (GO:0061727) 5 0 .49 - < 0.01 1.00E00 1.00E00 gastric emptying (GO:0035483) 1 0 .10 - < 0.01 1.00E00 1.00E00 gastric motility (GO:0035482) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of Notch signaling pathway involved in heart induction (GO:0035481) 4 0 .40 - < 0.01 1.00E00 1.00E00 cytosolic lipolysis (GO:0061725) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of Notch signaling pathway involved in heart induction (GO:0035480) 4 0 .40 - < 0.01 1.00E00 1.00E00 lipophagy (GO:0061724) 2 0 .20 - < 0.01 1.00E00 1.00E00 glycophagy (GO:0061723) 2 0 .20 - < 0.01 1.00E00 1.00E00 asymmetric neuroblast division (GO:0055059) 6 0 .59 - < 0.01 1.00E00 1.00E00 penile erection (GO:0043084) 4 0 .40 - < 0.01 1.00E00 1.00E00 glucose catabolic process to pyruvate (GO:0061718) 6 0 .59 - < 0.01 1.00E00 1.00E00 miRNA 2'-O-methylation (GO:0061715) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of vascular wound healing (GO:0035470) 4 0 .40 - < 0.01 1.00E00 1.00E00 amiloride transport (GO:0015898) 1 0 .10 - < 0.01 1.00E00 1.00E00 anastral spindle assembly (GO:0055048) 1 0 .10 - < 0.01 1.00E00 1.00E00 determination of pancreatic left/right asymmetry (GO:0035469) 4 0 .40 - < 0.01 1.00E00 1.00E00 cobalamin transport (GO:0015889) 4 0 .40 - < 0.01 1.00E00 1.00E00 thiamine transport (GO:0015888) 2 0 .20 - < 0.01 1.00E00 1.00E00 pantothenate transmembrane transport (GO:0015887) 1 0 .10 - < 0.01 1.00E00 1.00E00 FAD transport (GO:0015883) 1 0 .10 - < 0.01 1.00E00 1.00E00 creatine transmembrane transport (GO:0015881) 3 0 .30 - < 0.01 1.00E00 1.00E00 vesicle cargo loading (GO:0035459) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 intercellular bridge organization (GO:0043063) 1 0 .10 - < 0.01 1.00E00 1.00E00 meiotic metaphase I plate congression (GO:0043060) 2 0 .20 - < 0.01 1.00E00 1.00E00 biotin transport (GO:0015878) 3 0 .30 - < 0.01 1.00E00 1.00E00 acetylcholine transport (GO:0015870) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac muscle tissue development (GO:0055026) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle tissue development (GO:0055025) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle tissue development (GO:0055024) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle fiber development (GO:0055020) 1 0 .10 - < 0.01 1.00E00 1.00E00 forward locomotion (GO:0043056) 1 0 .10 - < 0.01 1.00E00 1.00E00 thermotaxis (GO:0043052) 1 0 .10 - < 0.01 1.00E00 1.00E00 tripeptide transmembrane transport (GO:0035443) 4 0 .40 - < 0.01 1.00E00 1.00E00 deadenylation-independent decapping of nuclear-transcribed mRNA (GO:0031087) 4 0 .40 - < 0.01 1.00E00 1.00E00 cytidine transport (GO:0015861) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle fiber development (GO:0055018) 1 0 .10 - < 0.01 1.00E00 1.00E00 atrial cardiac muscle cell development (GO:0055014) 2 0 .20 - < 0.01 1.00E00 1.00E00 atrial cardiac muscle cell differentiation (GO:0055011) 2 0 .20 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside diphosphate biosynthetic process (GO:0009197) 3 0 .30 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside diphosphate metabolic process (GO:0009196) 3 0 .30 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside diphosphate catabolic process (GO:0009195) 2 0 .20 - < 0.01 1.00E00 1.00E00 dolichyl monophosphate biosynthetic process (GO:0043048) 1 0 .10 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside diphosphate biosynthetic process (GO:0009194) 1 0 .10 - < 0.01 1.00E00 1.00E00 maintenance of protein localization in endoplasmic reticulum (GO:0035437) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 pyrimidine ribonucleoside diphosphate metabolic process (GO:0009193) 3 0 .30 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside diphosphate catabolic process (GO:0009192) 1 0 .10 - < 0.01 1.00E00 1.00E00 DNA methylation involved in embryo development (GO:0043045) 7 0 .69 - < 0.01 1.00E00 1.00E00 phosphate ion transmembrane transport (GO:0035435) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 cyclic nucleotide biosynthetic process (GO:0009190) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 amino acid activation for nonribosomal peptide biosynthetic process (GO:0043041) 1 0 .10 - < 0.01 1.00E00 1.00E00 guanine transport (GO:0015854) 1 0 .10 - < 0.01 1.00E00 1.00E00 adenine transport (GO:0015853) 1 0 .10 - < 0.01 1.00E00 1.00E00 atrial cardiac muscle tissue morphogenesis (GO:0055009) 4 0 .40 - < 0.01 1.00E00 1.00E00 ventricular cardiac myofibril assembly (GO:0055005) 2 0 .20 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside diphosphate biosynthetic process (GO:0009189) 4 0 .40 - < 0.01 1.00E00 1.00E00 ribonucleoside diphosphate biosynthetic process (GO:0009188) 5 0 .49 - < 0.01 1.00E00 1.00E00 cyclic nucleotide metabolic process (GO:0009187) 26 0 2.57 - < 0.01 1.65E-01 1.00E00 deoxyribonucleoside diphosphate metabolic process (GO:0009186) 6 0 .59 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleoside diphosphate catabolic process (GO:0009184) 1 0 .10 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleoside diphosphate biosynthetic process (GO:0009183) 1 0 .10 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleoside diphosphate metabolic process (GO:0009182) 3 0 .30 - < 0.01 1.00E00 1.00E00 purine ribonucleoside diphosphate biosynthetic process (GO:0009180) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of histone deacetylation (GO:0031064) 4 0 .40 - < 0.01 1.00E00 1.00E00 polyamine transport (GO:0015846) 1 0 .10 - < 0.01 1.00E00 1.00E00 aminergic neurotransmitter loading into synaptic vesicle (GO:0015842) 3 0 .30 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside monophosphate catabolic process (GO:0009178) 6 0 .59 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside monophosphate biosynthetic process (GO:0009177) 4 0 .40 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside monophosphate metabolic process (GO:0009176) 10 0 .99 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside monophosphate catabolic process (GO:0009175) 3 0 .30 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) 2 0 .20 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) 5 0 .49 - < 0.01 1.00E00 1.00E00 primary miRNA processing (GO:0031053) 8 0 .79 - < 0.01 1.00E00 1.00E00 chromosome breakage (GO:0031052) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone H3-Y41 phosphorylation (GO:0035409) 1 0 .10 - < 0.01 1.00E00 1.00E00 nucleoside biosynthetic process (GO:0009163) 9 0 .89 - < 0.01 1.00E00 1.00E00 histone H3-T11 phosphorylation (GO:0035407) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone-tyrosine phosphorylation (GO:0035406) 1 0 .10 - < 0.01 1.00E00 1.00E00 programmed DNA elimination (GO:0031049) 1 0 .10 - < 0.01 1.00E00 1.00E00 heterochromatin assembly by small RNA (GO:0031048) 3 0 .30 - < 0.01 1.00E00 1.00E00 threonine transport (GO:0015826) 1 0 .10 - < 0.01 1.00E00 1.00E00 ornithine transport (GO:0015822) 8 0 .79 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside monophosphate biosynthetic process (GO:0009157) 4 0 .40 - < 0.01 1.00E00 1.00E00 maintenance of rDNA (GO:0043007) 2 0 .20 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleotide biosynthetic process (GO:0009153) 2 0 .20 - < 0.01 1.00E00 1.00E00 activation of phospholipase A2 activity by calcium-mediated signaling (GO:0043006) 1 0 .10 - < 0.01 1.00E00 1.00E00 cytoplasmic sequestering of CFTR protein (GO:0043004) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of Golgi to plasma membrane CFTR protein transport (GO:0043002) 1 0 .10 - < 0.01 1.00E00 1.00E00 lysine transport (GO:0015819) 2 0 .20 - < 0.01 1.00E00 1.00E00 histidine transport (GO:0015817) 1 0 .10 - < 0.01 1.00E00 1.00E00 myosin filament assembly (GO:0031034) 4 0 .40 - < 0.01 1.00E00 1.00E00 myosin filament organization (GO:0031033) 4 0 .40 - < 0.01 1.00E00 1.00E00 gamma-aminobutyric acid transport (GO:0015812) 9 0 .89 - < 0.01 1.00E00 1.00E00 L-cystine transport (GO:0015811) 3 0 .30 - < 0.01 1.00E00 1.00E00 aspartate transmembrane transport (GO:0015810) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 pyrimidine nucleoside triphosphate catabolic process (GO:0009149) 3 0 .30 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 pyrimidine nucleoside triphosphate metabolic process (GO:0009147) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 purine nucleoside triphosphate catabolic process (GO:0009146) 5 0 .49 - < 0.01 1.00E00 1.00E00 nucleoside triphosphate catabolic process (GO:0009143) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 pyrimidine nucleoside diphosphate catabolic process (GO:0009140) 2 0 .20 - < 0.01 1.00E00 1.00E00 S-adenosyl-L-methionine transport (GO:0015805) 1 0 .10 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside diphosphate biosynthetic process (GO:0009139) 3 0 .30 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside diphosphate metabolic process (GO:0009138) 5 0 .49 - < 0.01 1.00E00 1.00E00 purine nucleoside diphosphate biosynthetic process (GO:0009136) 4 0 .40 - < 0.01 1.00E00 1.00E00 nucleoside diphosphate biosynthetic process (GO:0009133) 7 0 .69 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside monophosphate catabolic process (GO:0009131) 6 0 .59 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) 6 0 .59 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside monophosphate metabolic process (GO:0009129) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 peptide antigen transport (GO:0046968) 1 0 .10 - < 0.01 1.00E00 1.00E00 cytosol to endoplasmic reticulum transport (GO:0046967) 4 0 .40 - < 0.01 1.00E00 1.00E00 3'-phosphoadenosine 5'-phosphosulfate transport (GO:0046963) 1 0 .10 - < 0.01 1.00E00 1.00E00 sensitization (GO:0046960) 1 0 .10 - < 0.01 1.00E00 1.00E00 habituation (GO:0046959) 6 0 .59 - < 0.01 1.00E00 1.00E00 nonassociative learning (GO:0046958) 7 0 .69 - < 0.01 1.00E00 1.00E00 R-loop disassembly (GO:0062176) 5 0 .49 - < 0.01 1.00E00 1.00E00 purine nucleobase biosynthetic process (GO:0009113) 7 0 .69 - < 0.01 1.00E00 1.00E00 brexanolone metabolic process (GO:0062173) 1 0 .10 - < 0.01 1.00E00 1.00E00 vitamin catabolic process (GO:0009111) 6 0 .59 - < 0.01 1.00E00 1.00E00 ketone body catabolic process (GO:0046952) 3 0 .30 - < 0.01 1.00E00 1.00E00 ketone body biosynthetic process (GO:0046951) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular ketone body metabolic process (GO:0046950) 6 0 .59 - < 0.01 1.00E00 1.00E00 behavioral response to starvation (GO:0042595) 1 0 .10 - < 0.01 1.00E00 1.00E00 endothelin receptor signaling pathway (GO:0086100) 6 0 .59 - < 0.01 1.00E00 1.00E00 fatty-acyl-CoA biosynthetic process (GO:0046949) 5 0 .49 - < 0.01 1.00E00 1.00E00 lipoate biosynthetic process (GO:0009107) 1 0 .10 - < 0.01 1.00E00 1.00E00 lipoate metabolic process (GO:0009106) 2 0 .20 - < 0.01 1.00E00 1.00E00 hydroxylysine biosynthetic process (GO:0046947) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of substance P secretion, neurotransmission (GO:1904496) 1 0 .10 - < 0.01 1.00E00 1.00E00 hydroxylysine metabolic process (GO:0046946) 2 0 .20 - < 0.01 1.00E00 1.00E00 lipopolysaccharide catabolic process (GO:0009104) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of substance P secretion, neurotransmission (GO:1904494) 1 0 .10 - < 0.01 1.00E00 1.00E00 vascular endothelial cell response to fluid shear stress (GO:0097699) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to ciliary transition zone (GO:1904491) 6 0 .59 - < 0.01 1.00E00 1.00E00 telomere maintenance via base-excision repair (GO:0097698) 1 0 .10 - < 0.01 1.00E00 1.00E00 nucleoside monophosphate phosphorylation (GO:0046940) 2 0 .20 - < 0.01 1.00E00 1.00E00 establishment of RNA localization to telomere (GO:0097694) 2 0 .20 - < 0.01 1.00E00 1.00E00 histone H3-K4 monomethylation (GO:0097692) 8 0 .79 - < 0.01 1.00E00 1.00E00 protein folding in endoplasmic reticulum (GO:0034975) 5 0 .49 - < 0.01 1.00E00 1.00E00 histone H3-R17 methylation (GO:0034971) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone H3-R2 methylation (GO:0034970) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to tetrahydrofolate (GO:1904482) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to tetrahydrofolate (GO:1904481) 1 0 .10 - < 0.01 1.00E00 1.00E00 glutamate receptor clustering (GO:0097688) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of intestinal absorption (GO:1904480) 2 0 .20 - < 0.01 1.00E00 1.00E00 histone arginine methylation (GO:0034969) 5 0 .49 - < 0.01 1.00E00 1.00E00 double-strand break repair via alternative nonhomologous end joining (GO:0097681) 3 0 .30 - < 0.01 1.00E00 1.00E00 box H/ACA RNA processing (GO:0034964) 2 0 .20 - < 0.01 1.00E00 1.00E00 double-strand break repair via classical nonhomologous end joining (GO:0097680) 6 0 .59 - < 0.01 1.00E00 1.00E00 box C/D RNA processing (GO:0034963) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of transport across blood-brain barrier (GO:0150202) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of transport across blood-brain barrier (GO:0150201) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of transport across blood-brain barrier (GO:0150200) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of intestinal absorption (GO:1904479) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of endothelin production (GO:1904471) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone H3-K36 dimethylation (GO:0097676) 3 0 .30 - < 0.01 1.00E00 1.00E00 endothelin maturation (GO:0034959) 1 0 .10 - < 0.01 1.00E00 1.00E00 pteridine-containing compound catabolic process (GO:0042560) 1 0 .10 - < 0.01 1.00E00 1.00E00 DNA ADP-ribosylation (GO:0030592) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of substance P secretion (GO:1904460) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of substance P secretion (GO:1904458) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of neuronal action potential (GO:1904457) 3 0 .30 - < 0.01 1.00E00 1.00E00 fatty acid primary amide metabolic process (GO:0062126) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of neuronal action potential (GO:1904456) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of potassium:proton exchanging ATPase activity (GO:1904453) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of potassium:proton exchanging ATPase activity (GO:1904451) 1 0 .10 - < 0.01 1.00E00 1.00E00 tetrahydrofolylpolyglutamate biosynthetic process (GO:0046901) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of aspartate secretion (GO:1904450) 2 0 .20 - < 0.01 1.00E00 1.00E00 tetrahydrofolylpolyglutamate metabolic process (GO:0046900) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of dosage compensation by inactivation of X chromosome (GO:1900095) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell wall biogenesis (GO:0042546) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry (GO:1900094) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein N-linked glycosylation via arginine (GO:0042543) 1 0 .10 - < 0.01 1.00E00 1.00E00 ubiquitin-dependent SMAD protein catabolic process (GO:0030579) 5 0 .49 - < 0.01 1.00E00 1.00E00 Cajal body organization (GO:0030576) 4 0 .40 - < 0.01 1.00E00 1.00E00 bile acid catabolic process (GO:0030573) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of aspartate secretion (GO:1904448) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of translational initiation by eIF2 alpha phosphorylation (GO:0010998) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of establishment of Sertoli cell barrier (GO:1904445) 1 0 .10 - < 0.01 1.00E00 1.00E00 free ubiquitin chain polymerization (GO:0010994) 5 0 .49 - < 0.01 1.00E00 1.00E00 fatty acid primary amide biosynthetic process (GO:0062112) 1 0 .10 - < 0.01 1.00E00 1.00E00 zinc ion import into organelle (GO:0062111) 1 0 .10 - < 0.01 1.00E00 1.00E00 ubiquitin recycling (GO:0010992) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of thyroid gland epithelial cell proliferation (GO:1904442) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of thyroid gland epithelial cell proliferation (GO:1904441) 1 0 .10 - < 0.01 1.00E00 1.00E00 amylin receptor signaling pathway (GO:0097647) 5 0 .49 - < 0.01 1.00E00 1.00E00 hypotonic salinity response (GO:0042539) 2 0 .20 - < 0.01 1.00E00 1.00E00 hyperosmotic salinity response (GO:0042538) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of peptidyl-tyrosine autophosphorylation (GO:1900086) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of peptidyl-tyrosine autophosphorylation (GO:1900085) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of peptidyl-tyrosine autophosphorylation (GO:1900084) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of arginine catabolic process (GO:1900082) 1 0 .10 - < 0.01 1.00E00 1.00E00 L-ornithine import across plasma membrane (GO:0097640) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of arginine catabolic process (GO:1900081) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of low-density lipoprotein particle clearance (GO:0010989) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of iron ion import across plasma membrane (GO:1904439) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of low-density lipoprotein particle clearance (GO:0010988) 9 0 .89 - < 0.01 1.00E00 1.00E00 positive regulation of transferrin receptor binding (GO:1904437) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of lipoprotein particle clearance (GO:0010986) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of transferrin receptor binding (GO:1904435) 2 0 .20 - < 0.01 1.00E00 1.00E00 double-stranded RNA biosynthetic process (GO:0062103) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of ferrous iron binding (GO:1904434) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of high-density lipoprotein particle clearance (GO:0010983) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of high-density lipoprotein particle clearance (GO:0010982) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of ferrous iron binding (GO:1904432) 2 0 .20 - < 0.01 1.00E00 1.00E00 L-lysine import across plasma membrane (GO:0097639) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of t-circle formation (GO:1904431) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of programmed necrotic cell death (GO:0062100) 4 0 .40 - < 0.01 1.00E00 1.00E00 L-arginine import across plasma membrane (GO:0097638) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of t-circle formation (GO:1904430) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of arginine biosynthetic process (GO:1900079) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of vitamin D 24-hydroxylase activity (GO:0010980) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of neuromuscular synaptic transmission (GO:1900075) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of neuromuscular synaptic transmission (GO:1900073) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of t-circle formation (GO:1904429) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of vitamin D 24-hydroxylase activity (GO:0010979) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of tubulin deacetylation (GO:1904428) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of GTP binding (GO:1904426) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of GTP binding (GO:1904425) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of cellular hyperosmotic salinity response (GO:1900069) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of peroxisome organization (GO:1900063) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of microtubule nucleation (GO:0010968) 9 0 .89 - < 0.01 1.00E00 1.00E00 regulation of polyamine biosynthetic process (GO:0010967) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac ventricle development (GO:1904414) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of L-arginine import (GO:0010963) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of cardiac ventricle development (GO:1904412) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of secretory granule organization (GO:1904411) 3 0 .30 - < 0.01 1.00E00 1.00E00 O-glycan processing, core 1 (GO:0016267) 2 0 .20 - < 0.01 1.00E00 1.00E00 gap junction assembly (GO:0016264) 5 0 .49 - < 0.01 1.00E00 1.00E00 lipopolysaccharide metabolic process (GO:0008653) 1 0 .10 - < 0.01 1.00E00 1.00E00 selenocysteine catabolic process (GO:0016261) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular amino acid biosynthetic process (GO:0008652) 46 0 4.55 - < 0.01 3.27E-02 4.75E-01 positive regulation of retinoic acid biosynthetic process (GO:1900054) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of retinoic acid biosynthetic process (GO:1900053) 1 0 .10 - < 0.01 1.00E00 1.00E00 selenocysteine biosynthetic process (GO:0016260) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of retinoic acid biosynthetic process (GO:1900052) 2 0 .20 - < 0.01 1.00E00 1.00E00 serine phosphorylation of STAT protein (GO:0042501) 3 0 .30 - < 0.01 1.00E00 1.00E00 embryonic genitalia morphogenesis (GO:0030538) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of secretory granule organization (GO:1904409) 3 0 .30 - < 0.01 1.00E00 1.00E00 selenocysteine metabolic process (GO:0016259) 4 0 .40 - < 0.01 1.00E00 1.00E00 N-glycan processing to lysosome (GO:0016256) 1 0 .10 - < 0.01 1.00E00 1.00E00 attachment of GPI anchor to protein (GO:0016255) 5 0 .49 - < 0.01 1.00E00 1.00E00 androgen receptor signaling pathway (GO:0030521) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 intracellular estrogen receptor signaling pathway (GO:0030520) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 negative regulation of transcription by competitive promoter binding (GO:0010944) 8 0 .79 - < 0.01 1.00E00 1.00E00 protein deglutarylation (GO:0061698) 2 0 .20 - < 0.01 1.00E00 1.00E00 RNA interference (GO:0016246) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 positive regulation of necrotic cell death (GO:0010940) 10 0 .99 - < 0.01 1.00E00 1.00E00 positive regulation of cellular response to hypoxia (GO:1900039) 1 0 .10 - < 0.01 1.00E00 1.00E00 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO:0008635) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of autophagosome size (GO:0016243) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of cellular response to heat (GO:1900036) 1 0 .10 - < 0.01 1.00E00 1.00E00 cytoplasmic microtubule depolymerization (GO:0010938) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage tolerance induction (GO:0010933) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of macrophage tolerance induction (GO:0010932) 1 0 .10 - < 0.01 1.00E00 1.00E00 hormone-mediated apoptotic signaling pathway (GO:0008628) 2 0 .20 - < 0.01 1.00E00 1.00E00 intrinsic apoptotic signaling pathway in response to osmotic stress (GO:0008627) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of ruffle assembly (GO:1900028) 6 0 .59 - < 0.01 1.00E00 1.00E00 granzyme-mediated apoptotic signaling pathway (GO:0008626) 1 0 .10 - < 0.01 1.00E00 1.00E00 telomere capping (GO:0016233) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 seminal vesicle morphogenesis (GO:0061682) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of D-erythro-sphingosine kinase activity (GO:1900022) 1 0 .10 - < 0.01 1.00E00 1.00E00 inorganic diphosphate transport (GO:0030505) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of inositol-polyphosphate 5-phosphatase activity (GO:0010925) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of inositol-polyphosphate 5-phosphatase activity (GO:0010924) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of inositol phosphate biosynthetic process (GO:0010920) 2 0 .20 - < 0.01 1.00E00 1.00E00 guanosine metabolic process (GO:0008617) 1 0 .10 - < 0.01 1.00E00 1.00E00 evoked neurotransmitter secretion (GO:0061670) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial membrane potential (GO:0010918) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 spontaneous neurotransmitter secretion (GO:0061669) 7 0 .69 - < 0.01 1.00E00 1.00E00 mitochondrial ribosome assembly (GO:0061668) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of non-membrane spanning protein tyrosine kinase activity (GO:1903997) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of very-low-density lipoprotein particle remodeling (GO:0010903) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of very-low-density lipoprotein particle remodeling (GO:0010901) 2 0 .20 - < 0.01 1.00E00 1.00E00 muscle attachment (GO:0016203) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of TRAIL-activated apoptotic signaling pathway (GO:1903984) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization (GO:0061646) 2 0 .20 - < 0.01 1.00E00 1.00E00 chemorepulsion of axon (GO:0061643) 5 0 .49 - < 0.01 1.00E00 1.00E00 CENP-A containing chromatin organization (GO:0061641) 6 0 .59 - < 0.01 1.00E00 1.00E00 chemokine (C-X-C motif) ligand 9 production (GO:0035393) 1 0 .10 - < 0.01 1.00E00 1.00E00 Roundabout signaling pathway (GO:0035385) 5 0 .49 - < 0.01 1.00E00 1.00E00 thioester biosynthetic process (GO:0035384) 20 0 1.98 - < 0.01 2.51E-01 1.00E00 glycolytic process through fructose-1-phosphate (GO:0061625) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of protein targeting to mitochondrion (GO:1903955) 7 0 .69 - < 0.01 1.00E00 1.00E00 fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate (GO:0061624) 2 0 .20 - < 0.01 1.00E00 1.00E00 glycolytic process from galactose (GO:0061623) 3 0 .30 - < 0.01 1.00E00 1.00E00 glycolytic process through glucose-1-phosphate (GO:0061622) 4 0 .40 - < 0.01 1.00E00 1.00E00 canonical glycolysis (GO:0061621) 6 0 .59 - < 0.01 1.00E00 1.00E00 glycolytic process through glucose-6-phosphate (GO:0061620) 9 0 .89 - < 0.01 1.00E00 1.00E00 glycolytic process from mannose through fructose-6-phosphate (GO:0061619) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of atrial cardiac muscle cell action potential (GO:1903949) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to microtubule (GO:0035372) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 glycolytic process through fructose-6-phosphate (GO:0061615) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 pri-miRNA transcription by RNA polymerase II (GO:0061614) 2 0 .20 - < 0.01 1.00E00 1.00E00 myo-inositol transport (GO:0015798) 2 0 .20 - < 0.01 1.00E00 1.00E00 mannose to fructose-6-phosphate metabolic process (GO:0061611) 1 0 .10 - < 0.01 1.00E00 1.00E00 mannitol transport (GO:0015797) 1 0 .10 - < 0.01 1.00E00 1.00E00 glycerol-3-phosphate transmembrane transport (GO:0015794) 1 0 .10 - < 0.01 1.00E00 1.00E00 UDP-xylose transmembrane transport (GO:0015790) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of TORC2 signaling (GO:1903939) 3 0 .30 - < 0.01 1.00E00 1.00E00 thymine transport (GO:0035364) 1 0 .10 - < 0.01 1.00E00 1.00E00 UDP-glucose transmembrane transport (GO:0015786) 1 0 .10 - < 0.01 1.00E00 1.00E00 GDP-fucose transmembrane transport (GO:0015783) 1 0 .10 - < 0.01 1.00E00 1.00E00 CMP-N-acetylneuraminate transmembrane transport (GO:0015782) 1 0 .10 - < 0.01 1.00E00 1.00E00 nucleotide-sugar transmembrane transport (GO:0015780) 10 0 .99 - < 0.01 1.00E00 1.00E00 negative regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035359) 3 0 .30 - < 0.01 1.00E00 1.00E00 primary palate development (GO:1903929) 3 0 .30 - < 0.01 1.00E00 1.00E00 FAD transmembrane transport (GO:0035350) 1 0 .10 - < 0.01 1.00E00 1.00E00 polysaccharide transport (GO:0015774) 1 0 .10 - < 0.01 1.00E00 1.00E00 oligosaccharide transport (GO:0015772) 2 0 .20 - < 0.01 1.00E00 1.00E00 sucrose transport (GO:0015770) 2 0 .20 - < 0.01 1.00E00 1.00E00 viral budding via host ESCRT complex (GO:0039702) 8 0 .79 - < 0.01 1.00E00 1.00E00 hypoxanthine transport (GO:0035344) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation (GO:1903917) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation (GO:1903916) 1 0 .10 - < 0.01 1.00E00 1.00E00 angiotensin-activated signaling pathway involved in heart process (GO:0086098) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation (GO:1903912) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of the force of heart contraction by cardiac conduction (GO:0086092) 2 0 .20 - < 0.01 1.00E00 1.00E00 disaccharide transport (GO:0015766) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of receptor clustering (GO:1903910) 1 0 .10 - < 0.01 1.00E00 1.00E00 glucose-6-phosphate transport (GO:0015760) 5 0 .49 - < 0.01 1.00E00 1.00E00 valine biosynthetic process (GO:0009099) 3 0 .30 - < 0.01 1.00E00 1.00E00 leucine biosynthetic process (GO:0009098) 2 0 .20 - < 0.01 1.00E00 1.00E00 isoleucine biosynthetic process (GO:0009097) 2 0 .20 - < 0.01 1.00E00 1.00E00 long-chain fatty-acyl-CoA biosynthetic process (GO:0035338) 4 0 .40 - < 0.01 1.00E00 1.00E00 cysteine catabolic process (GO:0009093) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of hippo signaling (GO:0035332) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of hippo signaling (GO:0035331) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 regulation of hippo signaling (GO:0035330) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 positive regulation of establishment of T cell polarity (GO:1903905) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of establishment of T cell polarity (GO:1903904) 1 0 .10 - < 0.01 1.00E00 1.00E00 galactose transmembrane transport (GO:0015757) 1 0 .10 - < 0.01 1.00E00 1.00E00 fructose transmembrane transport (GO:0015755) 2 0 .20 - < 0.01 1.00E00 1.00E00 methionine catabolic process (GO:0009087) 1 0 .10 - < 0.01 1.00E00 1.00E00 methionine biosynthetic process (GO:0009086) 10 0 .99 - < 0.01 1.00E00 1.00E00 lysine biosynthetic process (GO:0009085) 1 0 .10 - < 0.01 1.00E00 1.00E00 glutamine family amino acid biosynthetic process (GO:0009084) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 branched-chain amino acid biosynthetic process (GO:0009082) 4 0 .40 - < 0.01 1.00E00 1.00E00 pyruvate family amino acid catabolic process (GO:0009080) 1 0 .10 - < 0.01 1.00E00 1.00E00 bundle of His cell-Purkinje myocyte adhesion involved in cell communication (GO:0086073) 6 0 .59 - < 0.01 1.00E00 1.00E00 urate transport (GO:0015747) 3 0 .30 - < 0.01 1.00E00 1.00E00 citrate transport (GO:0015746) 4 0 .40 - < 0.01 1.00E00 1.00E00 AV node cell-bundle of His cell adhesion involved in cell communication (GO:0086072) 1 0 .10 - < 0.01 1.00E00 1.00E00 succinate transport (GO:0015744) 7 0 .69 - < 0.01 1.00E00 1.00E00 malate transport (GO:0015743) 4 0 .40 - < 0.01 1.00E00 1.00E00 fumarate transport (GO:0015741) 1 0 .10 - < 0.01 1.00E00 1.00E00 pyruvate family amino acid metabolic process (GO:0009078) 2 0 .20 - < 0.01 1.00E00 1.00E00 serine family amino acid catabolic process (GO:0009071) 10 0 .99 - < 0.01 1.00E00 1.00E00 serine family amino acid biosynthetic process (GO:0009070) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 bundle of His cell to Purkinje myocyte communication (GO:0086069) 9 0 .89 - < 0.01 1.00E00 1.00E00 Purkinje myocyte to ventricular cardiac muscle cell communication (GO:0086068) 2 0 .20 - < 0.01 1.00E00 1.00E00 atrial cardiac muscle cell to AV node cell communication (GO:0086066) 6 0 .59 - < 0.01 1.00E00 1.00E00 sialic acid transport (GO:0015739) 2 0 .20 - < 0.01 1.00E00 1.00E00 cell communication by electrical coupling involved in cardiac conduction (GO:0086064) 4 0 .40 - < 0.01 1.00E00 1.00E00 taurine transport (GO:0015734) 6 0 .59 - < 0.01 1.00E00 1.00E00 aspartate family amino acid catabolic process (GO:0009068) 8 0 .79 - < 0.01 1.00E00 1.00E00 aspartate family amino acid biosynthetic process (GO:0009067) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 oxaloacetate transport (GO:0015729) 5 0 .49 - < 0.01 1.00E00 1.00E00 bundle of His cell to Purkinje myocyte communication by electrical coupling (GO:0086054) 1 0 .10 - < 0.01 1.00E00 1.00E00 AV node cell to bundle of His cell communication by electrical coupling (GO:0086053) 2 0 .20 - < 0.01 1.00E00 1.00E00 formate transport (GO:0015724) 1 0 .10 - < 0.01 1.00E00 1.00E00 bilirubin transport (GO:0015723) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of phosphatidylserine metabolic process (GO:0150178) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of phosphatidylethanolamine metabolic process (GO:0150175) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of phosphatidylcholine metabolic process (GO:0150173) 3 0 .30 - < 0.01 1.00E00 1.00E00 pentose-phosphate shunt, non-oxidative branch (GO:0009052) 5 0 .49 - < 0.01 1.00E00 1.00E00 pentose-phosphate shunt, oxidative branch (GO:0009051) 4 0 .40 - < 0.01 1.00E00 1.00E00 membrane depolarization during bundle of His cell action potential (GO:0086048) 2 0 .20 - < 0.01 1.00E00 1.00E00 membrane depolarization during Purkinje myocyte cell action potential (GO:0086047) 2 0 .20 - < 0.01 1.00E00 1.00E00 bundle of His cell action potential (GO:0086043) 2 0 .20 - < 0.01 1.00E00 1.00E00 cardiac muscle cell-cardiac muscle cell adhesion (GO:0086042) 7 0 .69 - < 0.01 1.00E00 1.00E00 hexose phosphate transport (GO:0015712) 5 0 .49 - < 0.01 1.00E00 1.00E00 dosage compensation by inactivation of X chromosome (GO:0009048) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 negative regulation of follicle-stimulating hormone secretion (GO:0046882) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of follicle-stimulating hormone secretion (GO:0046881) 2 0 .20 - < 0.01 1.00E00 1.00E00 thiosulfate transport (GO:0015709) 4 0 .40 - < 0.01 1.00E00 1.00E00 iodide transport (GO:0015705) 5 0 .49 - < 0.01 1.00E00 1.00E00 adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation (GO:0086030) 1 0 .10 - < 0.01 1.00E00 1.00E00 stomach development (GO:0062094) 2 0 .20 - < 0.01 1.00E00 1.00E00 Purkinje myocyte to ventricular cardiac muscle cell signaling (GO:0086029) 2 0 .20 - < 0.01 1.00E00 1.00E00 bundle of His cell to Purkinje myocyte signaling (GO:0086028) 2 0 .20 - < 0.01 1.00E00 1.00E00 atrial cardiac muscle cell to AV node cell signaling (GO:0086026) 6 0 .59 - < 0.01 1.00E00 1.00E00 cell-cell junction disassembly (GO:0150147) 1 0 .10 - < 0.01 1.00E00 1.00E00 Purkinje myocyte action potential (GO:0086017) 2 0 .20 - < 0.01 1.00E00 1.00E00 atrial cardiac muscle cell action potential (GO:0086014) 6 0 .59 - < 0.01 1.00E00 1.00E00 phosphatidylinositol dephosphorylation (GO:0046856) 28 0 2.77 - < 0.01 1.73E-01 9.70E-01 positive regulation of interleukin-33 production (GO:0150129) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of interleukin-33 production (GO:0150127) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of neuromuscular junction development (GO:1904397) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of skeletal muscle acetylcholine-gated channel clustering (GO:1904395) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of skeletal muscle acetylcholine-gated channel clustering (GO:1904394) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of odontogenesis of dentin-containing tooth (GO:0042489) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of odontogenesis of dentin-containing tooth (GO:0042488) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of odontogenesis (GO:0042483) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of transepithelial transport (GO:0150111) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of cholesterol esterification (GO:0150110) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to L-phenylalanine derivative (GO:1904386) 1 0 .10 - < 0.01 1.00E00 1.00E00 glycolipid transport (GO:0046836) 4 0 .40 - < 0.01 1.00E00 1.00E00 response to sodium phosphate (GO:1904383) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of RNA export from nucleus (GO:0046833) 4 0 .40 - < 0.01 1.00E00 1.00E00 mannose trimming involved in glycoprotein ERAD pathway (GO:1904382) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of RNA export from nucleus (GO:0046832) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of RNA export from nucleus (GO:0046831) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 endoplasmic reticulum mannose trimming (GO:1904380) 3 0 .30 - < 0.01 1.00E00 1.00E00 reactive gliosis (GO:0150103) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of microtubule anchoring at centrosome (GO:0150101) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to cytosolic proteasome complex involved in ERAD pathway (GO:1904379) 1 0 .10 - < 0.01 1.00E00 1.00E00 maintenance of unfolded protein involved in ERAD pathway (GO:1904378) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac epithelial to mesenchymal transition (GO:0062044) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of protein export from nucleus (GO:0046826) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to actin cortical patch (GO:1904372) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein localization to actin cortical patch (GO:1904370) 1 0 .10 - < 0.01 1.00E00 1.00E00 vacuole fusion (GO:0097576) 1 0 .10 - < 0.01 1.00E00 1.00E00 chemokinesis (GO:0042466) 1 0 .10 - < 0.01 1.00E00 1.00E00 kinesis (GO:0042465) 1 0 .10 - < 0.01 1.00E00 1.00E00 eye photoreceptor cell development (GO:0042462) 27 0 2.67 - < 0.01 1.68E-01 1.00E00 photoreceptor cell development (GO:0042461) 44 0 4.35 - < 0.01 3.06E-02 4.53E-01 maturation of SSU-rRNA (GO:0030490) 48 0 4.75 - < 0.01 2.00E-02 3.46E-01 positive regulation of chemokinesis (GO:1904367) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of chemokinesis (GO:1904365) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of calcitonin secretion (GO:1904364) 1 0 .10 - < 0.01 1.00E00 1.00E00 coreceptor-mediated virion attachment to host cell (GO:0046814) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of calcitonin secretion (GO:1904362) 1 0 .10 - < 0.01 1.00E00 1.00E00 ribonucleoside biosynthetic process (GO:0042455) 9 0 .89 - < 0.01 1.00E00 1.00E00 purine nucleoside biosynthetic process (GO:0042451) 9 0 .89 - < 0.01 1.00E00 1.00E00 arginine biosynthetic process via ornithine (GO:0042450) 1 0 .10 - < 0.01 1.00E00 1.00E00 tRNA methylation (GO:0030488) 33 0 3.26 - < 0.01 6.95E-02 7.22E-01 positive regulation of stress granule assembly (GO:0062029) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of stress granule assembly (GO:0062028) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of telomere maintenance via telomere lengthening (GO:1904358) 34 0 3.36 - < 0.01 6.96E-02 7.21E-01 negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process (GO:0062026) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0062025) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of telomere capping (GO:1904355) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 negative regulation of telomere capping (GO:1904354) 9 0 .89 - < 0.01 1.00E00 1.00E00 regulation of telomere capping (GO:1904353) 25 0 2.47 - < 0.01 1.63E-01 1.00E00 negative regulation of protein catabolic process in the vacuole (GO:1904351) 2 0 .20 - < 0.01 1.00E00 1.00E00 progesterone metabolic process (GO:0042448) 8 0 .79 - < 0.01 1.00E00 1.00E00 photoreceptor cell morphogenesis (GO:0008594) 6 0 .59 - < 0.01 1.00E00 1.00E00 hormone biosynthetic process (GO:0042446) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 regulation of Toll signaling pathway (GO:0008592) 4 0 .40 - < 0.01 1.00E00 1.00E00 mitochondrial double-strand break repair via homologous recombination (GO:0097552) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial double-strand break repair (GO:0097551) 1 0 .10 - < 0.01 1.00E00 1.00E00 phenylethylamine metabolic process (GO:0042443) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of phosphatidylcholine catabolic process (GO:0010899) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of small intestine smooth muscle contraction (GO:1904349) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of small intestine smooth muscle contraction (GO:1904348) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of small intestine smooth muscle contraction (GO:1904347) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of gastric mucosal blood circulation (GO:1904346) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of gastric mucosal blood circulation (GO:1904344) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of colon smooth muscle contraction (GO:1904343) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of colon smooth muscle contraction (GO:1904341) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of dopaminergic neuron differentiation (GO:1904340) 2 0 .20 - < 0.01 1.00E00 1.00E00 ethanolamine-containing compound metabolic process (GO:0042439) 7 0 .69 - < 0.01 1.00E00 1.00E00 indole-containing compound biosynthetic process (GO:0042435) 3 0 .30 - < 0.01 1.00E00 1.00E00 synaptic vesicle uncoating (GO:0016191) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of dopaminergic neuron differentiation (GO:1904339) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of dopaminergic neuron differentiation (GO:1904338) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of ductus arteriosus closure (GO:1904336) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of ductus arteriosus closure (GO:1904335) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity (GO:0062003) 1 0 .10 - < 0.01 1.00E00 1.00E00 synaptic vesicle to endosome fusion (GO:0016189) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity (GO:0062002) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of myofibroblast contraction (GO:1904330) 1 0 .10 - < 0.01 1.00E00 1.00E00 synaptic vesicle budding from presynaptic endocytic zone membrane (GO:0016185) 6 0 .59 - < 0.01 1.00E00 1.00E00 serotonin metabolic process (GO:0042428) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 thymus epithelium morphogenesis (GO:0097536) 1 0 .10 - < 0.01 1.00E00 1.00E00 serotonin biosynthetic process (GO:0042427) 3 0 .30 - < 0.01 1.00E00 1.00E00 lymphoid lineage cell migration into thymus (GO:0097535) 1 0 .10 - < 0.01 1.00E00 1.00E00 synaptic vesicle budding from endosome (GO:0016182) 3 0 .30 - < 0.01 1.00E00 1.00E00 lymphoid lineage cell migration (GO:0097534) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular stress response to acid chemical (GO:0097533) 2 0 .20 - < 0.01 1.00E00 1.00E00 catecholamine catabolic process (GO:0042424) 4 0 .40 - < 0.01 1.00E00 1.00E00 snRNA processing (GO:0016180) 24 0 2.37 - < 0.01 1.63E-01 1.00E00 stress response to acid chemical (GO:0097532) 2 0 .20 - < 0.01 1.00E00 1.00E00 dopamine catabolic process (GO:0042420) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of complement activation, alternative pathway (GO:0030451) 2 0 .20 - < 0.01 1.00E00 1.00E00 cholesterol transport involved in cholesterol storage (GO:0010879) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of myofibroblast contraction (GO:1904328) 2 0 .20 - < 0.01 1.00E00 1.00E00 lipid transport involved in lipid storage (GO:0010877) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein localization to cytosolic proteasome complex (GO:1904327) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of circadian sleep/wake cycle, wakefulness (GO:1904326) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of inhibitory G protein-coupled receptor phosphorylation (GO:1904325) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of inhibitory G protein-coupled receptor phosphorylation (GO:1904323) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to forskolin (GO:1904322) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 response to forskolin (GO:1904321) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 positive regulation of smooth muscle contraction involved in micturition (GO:1904320) 1 0 .10 - < 0.01 1.00E00 1.00E00 execution phase of necroptosis (GO:0097528) 2 0 .20 - < 0.01 1.00E00 1.00E00 epinephrine metabolic process (GO:0042414) 1 0 .10 - < 0.01 1.00E00 1.00E00 carnitine catabolic process (GO:0042413) 1 0 .10 - < 0.01 1.00E00 1.00E00 taurine biosynthetic process (GO:0042412) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of smooth muscle contraction involved in micturition (GO:1904318) 1 0 .10 - < 0.01 1.00E00 1.00E00 cristae formation (GO:0042407) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 thyroid hormone catabolic process (GO:0042404) 1 0 .10 - < 0.01 1.00E00 1.00E00 base-excision repair, AP site formation via deaminated base removal (GO:0097510) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of gastro-intestinal system smooth muscle contraction (GO:1904305) 1 0 .10 - < 0.01 1.00E00 1.00E00 sialylation (GO:0097503) 5 0 .49 - < 0.01 1.00E00 1.00E00 mannosylation (GO:0097502) 21 0 2.08 - < 0.01 2.52E-01 1.00E00 receptor localization to non-motile cilium (GO:0097500) 5 0 .49 - < 0.01 1.00E00 1.00E00 targeting of mRNA for destruction involved in RNA interference (GO:0030423) 4 0 .40 - < 0.01 1.00E00 1.00E00 production of siRNA involved in RNA interference (GO:0030422) 7 0 .69 - < 0.01 1.00E00 1.00E00 defecation (GO:0030421) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of proton-transporting ATPase activity, rotational mechanism (GO:0010849) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of chromatin disassembly (GO:0010848) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of chromatin assembly (GO:0010847) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 positive regulation of reciprocal meiotic recombination (GO:0010845) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of circadian sleep/wake cycle, wakefulness (GO:0010840) 2 0 .20 - < 0.01 1.00E00 1.00E00 calcium activated galactosylceramide scrambling (GO:0061591) 3 0 .30 - < 0.01 1.00E00 1.00E00 calcium activated phosphatidylcholine scrambling (GO:0061590) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of protein ADP-ribosylation (GO:0010836) 3 0 .30 - < 0.01 1.00E00 1.00E00 telomere maintenance via telomere lengthening (GO:0010833) 21 0 2.08 - < 0.01 2.52E-01 1.00E00 glycoside catabolic process (GO:0016139) 8 0 .79 - < 0.01 1.00E00 1.00E00 calcium activated phosphatidylserine scrambling (GO:0061589) 3 0 .30 - < 0.01 1.00E00 1.00E00 glycoside metabolic process (GO:0016137) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 calcium activated phospholipid scrambling (GO:0061588) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of transcription by transcription factor localization (GO:0061586) 1 0 .10 - < 0.01 1.00E00 1.00E00 brassinosteroid biosynthetic process (GO:0016132) 1 0 .10 - < 0.01 1.00E00 1.00E00 intestinal epithelial cell migration (GO:0061582) 2 0 .20 - < 0.01 1.00E00 1.00E00 brassinosteroid metabolic process (GO:0016131) 1 0 .10 - < 0.01 1.00E00 1.00E00 colon epithelial cell migration (GO:0061580) 1 0 .10 - < 0.01 1.00E00 1.00E00 DNA-templated viral transcription (GO:0039695) 1 0 .10 - < 0.01 1.00E00 1.00E00 viral RNA genome replication (GO:0039694) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 single stranded viral RNA replication via double stranded DNA intermediate (GO:0039692) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of centrosome duplication (GO:0010825) 6 0 .59 - < 0.01 1.00E00 1.00E00 phytosteroid biosynthetic process (GO:0016129) 1 0 .10 - < 0.01 1.00E00 1.00E00 phytosteroid metabolic process (GO:0016128) 1 0 .10 - < 0.01 1.00E00 1.00E00 sterol catabolic process (GO:0016127) 6 0 .59 - < 0.01 1.00E00 1.00E00 sterol biosynthetic process (GO:0016126) 35 0 3.46 - < 0.01 7.06E-02 7.29E-01 calcium ion transmembrane transport via high voltage-gated calcium channel (GO:0061577) 3 0 .30 - < 0.01 1.00E00 1.00E00 actin filament bundle retrograde transport (GO:0061573) 1 0 .10 - < 0.01 1.00E00 1.00E00 xanthophyll metabolic process (GO:0016122) 1 0 .10 - < 0.01 1.00E00 1.00E00 carotene catabolic process (GO:0016121) 2 0 .20 - < 0.01 1.00E00 1.00E00 TDP phosphorylation (GO:0061571) 1 0 .10 - < 0.01 1.00E00 1.00E00 dCDP phosphorylation (GO:0061570) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative stranded viral RNA replication (GO:0039689) 4 0 .40 - < 0.01 1.00E00 1.00E00 calcitonin catabolic process (GO:0010816) 1 0 .10 - < 0.01 1.00E00 1.00E00 substance P catabolic process (GO:0010814) 1 0 .10 - < 0.01 1.00E00 1.00E00 carotene metabolic process (GO:0016119) 2 0 .20 - < 0.01 1.00E00 1.00E00 UDP phosphorylation (GO:0061569) 1 0 .10 - < 0.01 1.00E00 1.00E00 GDP phosphorylation (GO:0061568) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of PERK-mediated unfolded protein response (GO:1903899) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of PERK-mediated unfolded protein response (GO:1903898) 4 0 .40 - < 0.01 1.00E00 1.00E00 carotenoid metabolic process (GO:0016116) 2 0 .20 - < 0.01 1.00E00 1.00E00 dCMP phosphorylation (GO:0061567) 1 0 .10 - < 0.01 1.00E00 1.00E00 terpenoid catabolic process (GO:0016115) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of PERK-mediated unfolded protein response (GO:1903897) 7 0 .69 - < 0.01 1.00E00 1.00E00 CMP phosphorylation (GO:0061566) 1 0 .10 - < 0.01 1.00E00 1.00E00 dAMP phosphorylation (GO:0061565) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of IRE1-mediated unfolded protein response (GO:1903896) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of IRE1-mediated unfolded protein response (GO:1903895) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of IRE1-mediated unfolded protein response (GO:1903894) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of ATF6-mediated unfolded protein response (GO:1903893) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of ATF6-mediated unfolded protein response (GO:1903892) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of ATF6-mediated unfolded protein response (GO:1903891) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic vesicle priming (GO:0010808) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of synaptic vesicle priming (GO:0010807) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 tetraterpenoid metabolic process (GO:0016108) 2 0 .20 - < 0.01 1.00E00 1.00E00 sesquiterpenoid catabolic process (GO:0016107) 1 0 .10 - < 0.01 1.00E00 1.00E00 triterpenoid biosynthetic process (GO:0016104) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of chemokine (C-C motif) ligand 20 production (GO:1903886) 1 0 .10 - < 0.01 1.00E00 1.00E00 diterpenoid catabolic process (GO:0016103) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of chemokine (C-C motif) ligand 20 production (GO:1903884) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-17-mediated signaling pathway (GO:1903883) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of interleukin-17-mediated signaling pathway (GO:1903881) 1 0 .10 - < 0.01 1.00E00 1.00E00 glutamate secretion, neurotransmission (GO:0061535) 2 0 .20 - < 0.01 1.00E00 1.00E00 gamma-aminobutyric acid secretion, neurotransmission (GO:0061534) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of dendrite extension (GO:1903861) 23 0 2.27 - < 0.01 2.61E-01 1.00E00 negative regulation of dendrite extension (GO:1903860) 4 0 .40 - < 0.01 1.00E00 1.00E00 brain segmentation (GO:0035284) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of dendrite extension (GO:1903859) 26 0 2.57 - < 0.01 1.65E-01 1.00E00 central nervous system segmentation (GO:0035283) 3 0 .30 - < 0.01 1.00E00 1.00E00 acetylcholine secretion (GO:0061526) 1 0 .10 - < 0.01 1.00E00 1.00E00 hindgut development (GO:0061525) 5 0 .49 - < 0.01 1.00E00 1.00E00 pre-miRNA export from nucleus (GO:0035281) 1 0 .10 - < 0.01 1.00E00 1.00E00 miRNA loading onto RISC involved in gene silencing by miRNA (GO:0035280) 7 0 .69 - < 0.01 1.00E00 1.00E00 cilium disassembly (GO:0061523) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cristae formation (GO:1903852) 3 0 .30 - < 0.01 1.00E00 1.00E00 Langerhans cell differentiation (GO:0061520) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of cristae formation (GO:1903850) 4 0 .40 - < 0.01 1.00E00 1.00E00 mRNA cleavage involved in gene silencing by miRNA (GO:0035279) 2 0 .20 - < 0.01 1.00E00 1.00E00 macrophage homeostasis (GO:0061519) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cellular response to transforming growth factor beta stimulus (GO:1903845) 3 0 .30 - < 0.01 1.00E00 1.00E00 interleukin-34-mediated signaling pathway (GO:0061514) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to cilium (GO:0061512) 53 0 5.24 - < 0.01 1.34E-02 2.61E-01 cellular response to arsenite ion (GO:1903843) 4 0 .40 - < 0.01 1.00E00 1.00E00 response to arsenite ion (GO:1903842) 4 0 .40 - < 0.01 1.00E00 1.00E00 centriole elongation (GO:0061511) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to arsenite(3-) (GO:1903841) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to arsenite(3-) (GO:1903840) 1 0 .10 - < 0.01 1.00E00 1.00E00 mercury ion transport (GO:0015694) 1 0 .10 - < 0.01 1.00E00 1.00E00 lead ion transport (GO:0015692) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein O-linked mannosylation (GO:0035269) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 protein mannosylation (GO:0035268) 20 0 1.98 - < 0.01 2.51E-01 1.00E00 CDP phosphorylation (GO:0061508) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of mRNA 3'-UTR binding (GO:1903839) 1 0 .10 - < 0.01 1.00E00 1.00E00 gonad morphogenesis (GO:0035262) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of mRNA 3'-UTR binding (GO:1903837) 1 0 .10 - < 0.01 1.00E00 1.00E00 external genitalia morphogenesis (GO:0035261) 2 0 .20 - < 0.01 1.00E00 1.00E00 internal genitalia morphogenesis (GO:0035260) 1 0 .10 - < 0.01 1.00E00 1.00E00 molybdate ion transport (GO:0015689) 1 0 .10 - < 0.01 1.00E00 1.00E00 magnesium ion transmembrane transport (GO:1903830) 2 0 .20 - < 0.01 1.00E00 1.00E00 arginine transmembrane transport (GO:1903826) 5 0 .49 - < 0.01 1.00E00 1.00E00 plasma membrane copper ion transport (GO:0015679) 2 0 .20 - < 0.01 1.00E00 1.00E00 vanadium ion transport (GO:0015676) 1 0 .10 - < 0.01 1.00E00 1.00E00 nickel cation transport (GO:0015675) 2 0 .20 - < 0.01 1.00E00 1.00E00 oxygen transport (GO:0015671) 2 0 .20 - < 0.01 1.00E00 1.00E00 peptidyl-arginine omega-N-methylation (GO:0035247) 3 0 .30 - < 0.01 1.00E00 1.00E00 peptidyl-arginine N-methylation (GO:0035246) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of voltage-gated potassium channel activity (GO:1903817) 9 0 .89 - < 0.01 1.00E00 1.00E00 L-serine import across plasma membrane (GO:1903812) 1 0 .10 - < 0.01 1.00E00 1.00E00 L-histidine import across plasma membrane (GO:1903810) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of glutamate-cysteine ligase activity (GO:0035229) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of glutamate-cysteine ligase activity (GO:0035227) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell competition in a multicellular organism (GO:0035212) 1 0 .10 - < 0.01 1.00E00 1.00E00 neuroinflammatory response (GO:0150076) 6 0 .59 - < 0.01 1.00E00 1.00E00 transport of virus (GO:0046794) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of deacetylase activity (GO:0150066) 2 0 .20 - < 0.01 1.00E00 1.00E00 viral replication complex formation and maintenance (GO:0046786) 1 0 .10 - < 0.01 1.00E00 1.00E00 microtubule polymerization (GO:0046785) 31 0 3.07 - < 0.01 1.09E-01 9.05E-01 viral mRNA export from host cell nucleus (GO:0046784) 7 0 .69 - < 0.01 1.00E00 1.00E00 viral budding from plasma membrane (GO:0046761) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to lysosome (GO:0150033) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to lysosome (GO:0150032) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein localization to lysosome (GO:0150031) 2 0 .20 - < 0.01 1.00E00 1.00E00 viral budding (GO:0046755) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 viral exocytosis (GO:0046754) 1 0 .10 - < 0.01 1.00E00 1.00E00 non-lytic viral release (GO:0046753) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of ERAD pathway (GO:1904294) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 viral capsid secondary envelopment (GO:0046745) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of ERAD pathway (GO:1904293) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of ERAD pathway (GO:1904292) 19 0 1.88 - < 0.01 4.08E-01 1.00E00 protein localization to non-motile cilium (GO:0097499) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 positive regulation of mitotic DNA damage checkpoint (GO:1904291) 1 0 .10 - < 0.01 1.00E00 1.00E00 endothelial tube lumen extension (GO:0097498) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of mitotic DNA damage checkpoint (GO:1904290) 1 0 .10 - < 0.01 1.00E00 1.00E00 blood vessel endothelial cell delamination (GO:0097497) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to histamine (GO:0034776) 6 0 .59 - < 0.01 1.00E00 1.00E00 glutathione transmembrane transport (GO:0034775) 4 0 .40 - < 0.01 1.00E00 1.00E00 histone H4-K20 trimethylation (GO:0034773) 7 0 .69 - < 0.01 1.00E00 1.00E00 histone H4-K20 methylation (GO:0034770) 9 0 .89 - < 0.01 1.00E00 1.00E00 positive regulation of neuron projection arborization (GO:0150012) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of neuron projection arborization (GO:0150011) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 regulation of mitotic DNA damage checkpoint (GO:1904289) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:1904283) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:1904282) 1 0 .10 - < 0.01 1.00E00 1.00E00 dendrite extension (GO:0097484) 10 0 .99 - < 0.01 1.00E00 1.00E00 phylloquinone catabolic process (GO:0042376) 1 0 .10 - < 0.01 1.00E00 1.00E00 phylloquinone metabolic process (GO:0042374) 1 0 .10 - < 0.01 1.00E00 1.00E00 vitamin K metabolic process (GO:0042373) 4 0 .40 - < 0.01 1.00E00 1.00E00 vitamin K biosynthetic process (GO:0042371) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of iron ion transmembrane transport (GO:0034760) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation by virus of viral protein levels in host cell (GO:0046726) 4 0 .40 - < 0.01 1.00E00 1.00E00 tricellular tight junction assembly (GO:1904274) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation by virus of viral protein levels in host cell (GO:0046725) 2 0 .20 - < 0.01 1.00E00 1.00E00 oxalic acid secretion (GO:0046724) 2 0 .20 - < 0.01 1.00E00 1.00E00 lactic acid secretion (GO:0046722) 1 0 .10 - < 0.01 1.00E00 1.00E00 vitamin D catabolic process (GO:0042369) 3 0 .30 - < 0.01 1.00E00 1.00E00 vitamin D biosynthetic process (GO:0042368) 3 0 .30 - < 0.01 1.00E00 1.00E00 cobalamin catabolic process (GO:0042366) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of iron ion transport (GO:0034757) 3 0 .30 - < 0.01 1.00E00 1.00E00 retinal cone cell apoptotic process (GO:0097474) 1 0 .10 - < 0.01 1.00E00 1.00E00 water-soluble vitamin catabolic process (GO:0042365) 1 0 .10 - < 0.01 1.00E00 1.00E00 retinal rod cell apoptotic process (GO:0097473) 1 0 .10 - < 0.01 1.00E00 1.00E00 fat-soluble vitamin catabolic process (GO:0042363) 5 0 .49 - < 0.01 1.00E00 1.00E00 fat-soluble vitamin biosynthetic process (GO:0042362) 6 0 .59 - < 0.01 1.00E00 1.00E00 vitamin E metabolic process (GO:0042360) 2 0 .20 - < 0.01 1.00E00 1.00E00 membrane disassembly (GO:0030397) 5 0 .49 - < 0.01 1.00E00 1.00E00 fructosamine catabolic process (GO:0030392) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation by virus of viral protein levels in host cell (GO:0046719) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of Schwann cell chemotaxis (GO:1904268) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of Schwann cell chemotaxis (GO:1904266) 1 0 .10 - < 0.01 1.00E00 1.00E00 borate transport (GO:0046713) 1 0 .10 - < 0.01 1.00E00 1.00E00 GDP catabolic process (GO:0046712) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of basement membrane assembly involved in embryonic body morphogenesis (GO:1904261) 5 0 .49 - < 0.01 1.00E00 1.00E00 programmed cell death in response to reactive oxygen species (GO:0097468) 2 0 .20 - < 0.01 1.00E00 1.00E00 GDP biosynthetic process (GO:0046711) 1 0 .10 - < 0.01 1.00E00 1.00E00 GDP metabolic process (GO:0046710) 2 0 .20 - < 0.01 1.00E00 1.00E00 vitamin D metabolic process (GO:0042359) 9 0 .89 - < 0.01 1.00E00 1.00E00 ubiquitin-dependent glycoprotein ERAD pathway (GO:0097466) 6 0 .59 - < 0.01 1.00E00 1.00E00 thiamine diphosphate metabolic process (GO:0042357) 2 0 .20 - < 0.01 1.00E00 1.00E00 'de novo' GDP-L-fucose biosynthetic process (GO:0042351) 2 0 .20 - < 0.01 1.00E00 1.00E00 GDP-L-fucose biosynthetic process (GO:0042350) 2 0 .20 - < 0.01 1.00E00 1.00E00 sperm mitochondrion organization (GO:0030382) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of basement membrane assembly involved in embryonic body morphogenesis (GO:1904259) 5 0 .49 - < 0.01 1.00E00 1.00E00 IDP catabolic process (GO:0046709) 2 0 .20 - < 0.01 1.00E00 1.00E00 IDP metabolic process (GO:0046707) 2 0 .20 - < 0.01 1.00E00 1.00E00 CDP biosynthetic process (GO:0046705) 1 0 .10 - < 0.01 1.00E00 1.00E00 CDP metabolic process (GO:0046704) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of bile acid metabolic process (GO:1904252) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of polynucleotide adenylyltransferase activity (GO:1904247) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of multivesicular body size (GO:0010796) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of ubiquinone biosynthetic process (GO:0010795) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of pancreatic trypsinogen secretion (GO:1904244) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mRNA export from nucleus (GO:0010793) 7 0 .69 - < 0.01 1.00E00 1.00E00 DNA double-strand break processing involved in repair via single-strand annealing (GO:0010792) 5 0 .49 - < 0.01 1.00E00 1.00E00 monoterpenoid metabolic process (GO:0016098) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of pancreatic trypsinogen secretion (GO:1904242) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly (GO:1904240) 1 0 .10 - < 0.01 1.00E00 1.00E00 polyprenol catabolic process (GO:0016095) 2 0 .20 - < 0.01 1.00E00 1.00E00 keratan sulfate metabolic process (GO:0042339) 1 0 .10 - < 0.01 1.00E00 1.00E00 polyprenol biosynthetic process (GO:0016094) 3 0 .30 - < 0.01 1.00E00 1.00E00 histone H3-K79 methylation (GO:0034729) 1 0 .10 - < 0.01 1.00E00 1.00E00 polyprenol metabolic process (GO:0016093) 7 0 .69 - < 0.01 1.00E00 1.00E00 cuticle development (GO:0042335) 2 0 .20 - < 0.01 1.00E00 1.00E00 DNA replication-independent nucleosome organization (GO:0034724) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 DNA replication-dependent nucleosome organization (GO:0034723) 9 0 .89 - < 0.01 1.00E00 1.00E00 histone H3-K4 demethylation (GO:0034720) 8 0 .79 - < 0.01 1.00E00 1.00E00 meiotic sister chromatid cohesion involved in meiosis I (GO:0010789) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly (GO:1904239) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of aconitate hydratase activity (GO:1904234) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of aconitate hydratase activity (GO:1904232) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of succinate dehydrogenase activity (GO:1904231) 2 0 .20 - < 0.01 1.00E00 1.00E00 synaptic vesicle docking (GO:0016081) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 synaptic vesicle targeting (GO:0016080) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of circadian sleep/wake cycle, non-REM sleep (GO:0042323) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of circadian sleep/wake cycle, REM sleep (GO:0042322) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of circadian sleep/wake cycle, sleep (GO:0042321) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of circadian sleep/wake cycle, REM sleep (GO:0042320) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of succinate dehydrogenase activity (GO:1904229) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of glycogen synthase activity, transferring glucose-1-phosphate (GO:1904227) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of glycogen synthase activity, transferring glucose-1-phosphate (GO:1904226) 1 0 .10 - < 0.01 1.00E00 1.00E00 tRNA catabolic process (GO:0016078) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of serine C-palmitoyltransferase activity (GO:1904222) 3 0 .30 - < 0.01 1.00E00 1.00E00 sno(s)RNA catabolic process (GO:0016077) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of serine C-palmitoyltransferase activity (GO:1904221) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein maturation by iron-sulfur cluster transfer (GO:0097428) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 snRNA catabolic process (GO:0016076) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of serine C-palmitoyltransferase activity (GO:1904220) 4 0 .40 - < 0.01 1.00E00 1.00E00 sno(s)RNA metabolic process (GO:0016074) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 snRNA metabolic process (GO:0016073) 33 0 3.26 - < 0.01 6.95E-02 7.21E-01 penicillin metabolic process (GO:0042316) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein kinase C deactivation (GO:0042313) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity (GO:1904219) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage (GO:0010767) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity (GO:1904217) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of fibroblast migration (GO:0010764) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of iodide transmembrane transport (GO:1904213) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of iodide transmembrane transport (GO:1904212) 1 0 .10 - < 0.01 1.00E00 1.00E00 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol (GO:1904211) 1 0 .10 - < 0.01 1.00E00 1.00E00 homoiothermy (GO:0042309) 1 0 .10 - < 0.01 1.00E00 1.00E00 adaptation of rhodopsin mediated signaling (GO:0016062) 1 0 .10 - < 0.01 1.00E00 1.00E00 DNA damage response, signal transduction by p53 class mediator (GO:0030330) 31 0 3.07 - < 0.01 1.09E-01 9.05E-01 positive regulation of skeletal muscle hypertrophy (GO:1904206) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of skeletal muscle hypertrophy (GO:1904205) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle hypertrophy (GO:1904204) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of cGMP-mediated signaling (GO:0010753) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of iodide transport (GO:1904202) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of iodide transport (GO:1904201) 1 0 .10 - < 0.01 1.00E00 1.00E00 rhodopsin mediated signaling pathway (GO:0016056) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of nitric oxide mediated signal transduction (GO:0010750) 3 0 .30 - < 0.01 1.00E00 1.00E00 iodide transmembrane transport (GO:1904200) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to raffinose (GO:0097403) 1 0 .10 - < 0.01 1.00E00 1.00E00 neuroblast migration (GO:0097402) 2 0 .20 - < 0.01 1.00E00 1.00E00 interleukin-17-mediated signaling pathway (GO:0097400) 9 0 .89 - < 0.01 1.00E00 1.00E00 prenylcysteine metabolic process (GO:0030329) 2 0 .20 - < 0.01 1.00E00 1.00E00 prenylcysteine catabolic process (GO:0030328) 2 0 .20 - < 0.01 1.00E00 1.00E00 prenylated protein catabolic process (GO:0030327) 3 0 .30 - < 0.01 1.00E00 1.00E00 adrenal gland development (GO:0030325) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 stabilization of membrane potential (GO:0030322) 10 0 .99 - < 0.01 1.00E00 1.00E00 transepithelial chloride transport (GO:0030321) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of long-chain fatty acid import across plasma membrane (GO:0010747) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of transcription via serum response element binding (GO:0010735) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of protein glutathionylation (GO:0010734) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein glutathionylation (GO:0010732) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to phosphate starvation (GO:0016036) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of hydrogen peroxide biosynthetic process (GO:0010730) 4 0 .40 - < 0.01 1.00E00 1.00E00 memory T cell proliferation (GO:0061485) 1 0 .10 - < 0.01 1.00E00 1.00E00 tRNA import into mitochondrion (GO:0016031) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to TNF agonist (GO:0061481) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of intestinal cholesterol absorption (GO:0030300) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of hydrogen peroxide biosynthetic process (GO:0010729) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of hydrogen peroxide biosynthetic process (GO:0010728) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of ferrochelatase activity (GO:0010722) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to anticoagulant (GO:0061476) 1 0 .10 - < 0.01 1.00E00 1.00E00 CDP-diacylglycerol biosynthetic process (GO:0016024) 3 0 .30 - < 0.01 1.00E00 1.00E00 T follicular helper cell differentiation (GO:0061470) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of inorganic anion transmembrane transport (GO:1903796) 1 0 .10 - < 0.01 1.00E00 1.00E00 guanine nucleotide transmembrane transport (GO:1903790) 4 0 .40 - < 0.01 1.00E00 1.00E00 glycolysis from storage polysaccharide through glucose-1-phosphate (GO:0093001) 1 0 .10 - < 0.01 1.00E00 1.00E00 globoside biosynthetic process via lactosylceramide (GO:0010707) 1 0 .10 - < 0.01 1.00E00 1.00E00 meiotic DNA double-strand break processing involved in reciprocal meiotic recombination (GO:0010705) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of norepinephrine secretion (GO:0010701) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of glutathione biosynthetic process (GO:1903788) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of glutathione biosynthetic process (GO:1903786) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac conduction (GO:1903781) 1 0 .10 - < 0.01 1.00E00 1.00E00 trophoblast cell migration (GO:0061450) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac conduction (GO:1903780) 1 0 .10 - < 0.01 1.00E00 1.00E00 charged-tRNA amino acid modification (GO:0019988) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cardiac conduction (GO:1903779) 8 0 .79 - < 0.01 1.00E00 1.00E00 translesion synthesis (GO:0019985) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 protein localization to vacuolar membrane (GO:1903778) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of DNA double-strand break processing (GO:1903775) 2 0 .20 - < 0.01 1.00E00 1.00E00 endocardial cushion cell development (GO:0061444) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of viral budding via host ESCRT complex (GO:1903774) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of viral budding via host ESCRT complex (GO:1903772) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of beta-galactosidase activity (GO:1903771) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of beta-galactosidase activity (GO:1903770) 1 0 .10 - < 0.01 1.00E00 1.00E00 establishment of skin barrier (GO:0061436) 19 0 1.88 - < 0.01 4.08E-01 1.00E00 positive regulation of potassium ion export across plasma membrane (GO:1903766) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to caloric restriction (GO:0061433) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization (GO:1903762) 1 0 .10 - < 0.01 1.00E00 1.00E00 bone trabecula morphogenesis (GO:0061430) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization (GO:1903760) 2 0 .20 - < 0.01 1.00E00 1.00E00 hatching (GO:0035188) 31 0 3.07 - < 0.01 1.09E-01 9.04E-01 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia (GO:0061428) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of SUMO transferase activity (GO:1903755) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of p38MAPK cascade (GO:1903753) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide (GO:1903751) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide (GO:1903750) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of RIG-I signaling pathway (GO:0039536) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of RIG-I signaling pathway (GO:0039535) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 negative regulation of MDA-5 signaling pathway (GO:0039534) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of MDA-5 signaling pathway (GO:0039533) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039532) 10 0 .99 - < 0.01 1.00E00 1.00E00 regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) 20 0 1.98 - < 0.01 2.51E-01 1.00E00 positive regulation of establishment of protein localization to mitochondrion (GO:1903749) 10 0 .99 - < 0.01 1.00E00 1.00E00 positive regulation of anterograde synaptic vesicle transport (GO:1903744) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of anterograde synaptic vesicle transport (GO:1903743) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of anterograde synaptic vesicle transport (GO:1903742) 3 0 .30 - < 0.01 1.00E00 1.00E00 suppression by virus of host autophagy (GO:0039521) 1 0 .10 - < 0.01 1.00E00 1.00E00 induction by virus of host autophagy (GO:0039520) 2 0 .20 - < 0.01 1.00E00 1.00E00 post-embryonic hemopoiesis (GO:0035166) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of transcription from RNA polymerase II promoter in response to heat stress (GO:0061408) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH (GO:0061402) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion (GO:0061400) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of phosphatidate phosphatase activity (GO:1903730) 1 0 .10 - < 0.01 1.00E00 1.00E00 modulation by virus of host autophagy (GO:0039519) 3 0 .30 - < 0.01 1.00E00 1.00E00 cAMP-mediated signaling (GO:0019933) 22 0 2.18 - < 0.01 2.56E-01 1.00E00 positive regulation of centriole elongation (GO:1903724) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of centriole elongation (GO:1903723) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of centriole elongation (GO:1903722) 6 0 .59 - < 0.01 1.00E00 1.00E00 cysteine transmembrane transport (GO:1903712) 2 0 .20 - < 0.01 1.00E00 1.00E00 spermine transmembrane transport (GO:1903710) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine (GO:0019919) 2 0 .20 - < 0.01 1.00E00 1.00E00 peptidyl-arginine methylation, to symmetrical-dimethyl arginine (GO:0019918) 1 0 .10 - < 0.01 1.00E00 1.00E00 uterine gland development (GO:1903709) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of production of siRNA involved in RNA interference (GO:1903704) 1 0 .10 - < 0.01 1.00E00 1.00E00 substantia propria of cornea development (GO:1903701) 1 0 .10 - < 0.01 1.00E00 1.00E00 post-embryonic forelimb morphogenesis (GO:0035128) 1 0 .10 - < 0.01 1.00E00 1.00E00 post-embryonic limb morphogenesis (GO:0035127) 1 0 .10 - < 0.01 1.00E00 1.00E00 post-embryonic appendage morphogenesis (GO:0035120) 1 0 .10 - < 0.01 1.00E00 1.00E00 dendritic spine morphogenesis (GO:0060997) 20 0 1.98 - < 0.01 2.51E-01 1.00E00 cell-cell signaling involved in kidney development (GO:0060995) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of transcription from RNA polymerase II promoter involved in kidney development (GO:0060994) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to fungicide (GO:0060992) 1 0 .10 - < 0.01 1.00E00 1.00E00 lipid tube assembly involved in organelle fusion (GO:0060989) 1 0 .10 - < 0.01 1.00E00 1.00E00 epicardium-derived cardiac vascular smooth muscle cell differentiation (GO:0060983) 2 0 .20 - < 0.01 1.00E00 1.00E00 cell migration involved in coronary angiogenesis (GO:0060981) 1 0 .10 - < 0.01 1.00E00 1.00E00 operant conditioning (GO:0035106) 4 0 .40 - < 0.01 1.00E00 1.00E00 cardioblast migration to the midline involved in heart field formation (GO:0060975) 1 0 .10 - < 0.01 1.00E00 1.00E00 embryonic heart tube left/right pattern formation (GO:0060971) 5 0 .49 - < 0.01 1.00E00 1.00E00 response to pyrethroid (GO:0046684) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of insulin secretion (GO:0046676) 39 0 3.86 - < 0.01 4.60E-02 5.73E-01 positive regulation of retinal cell programmed cell death (GO:0046670) 1 0 .10 - < 0.01 1.00E00 1.00E00 epithelial to mesenchymal transition involved in cardiac fibroblast development (GO:0060940) 1 0 .10 - < 0.01 1.00E00 1.00E00 retinal cell programmed cell death (GO:0046666) 3 0 .30 - < 0.01 1.00E00 1.00E00 response to luteinizing hormone (GO:0034699) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to prostaglandin E (GO:0034695) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 epicardium-derived cardiac fibroblast cell development (GO:0060939) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to prostaglandin (GO:0034694) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 epicardium-derived cardiac fibroblast cell differentiation (GO:0060938) 2 0 .20 - < 0.01 1.00E00 1.00E00 cardiac fibroblast cell development (GO:0060936) 2 0 .20 - < 0.01 1.00E00 1.00E00 cardiac fibroblast cell differentiation (GO:0060935) 2 0 .20 - < 0.01 1.00E00 1.00E00 His-Purkinje system cell differentiation (GO:0060932) 1 0 .10 - < 0.01 1.00E00 1.00E00 sinoatrial node cell fate commitment (GO:0060930) 1 0 .10 - < 0.01 1.00E00 1.00E00 atrioventricular node cell fate commitment (GO:0060929) 1 0 .10 - < 0.01 1.00E00 1.00E00 atrioventricular node cell development (GO:0060928) 3 0 .30 - < 0.01 1.00E00 1.00E00 cardiac pacemaker cell fate commitment (GO:0060927) 2 0 .20 - < 0.01 1.00E00 1.00E00 atrioventricular node cell differentiation (GO:0060922) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization (GO:1904199) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of granulosa cell proliferation (GO:1904197) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of granulosa cell proliferation (GO:1904195) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-17 (GO:0097398) 10 0 .99 - < 0.01 1.00E00 1.00E00 response to interleukin-17 (GO:0097396) 10 0 .99 - < 0.01 1.00E00 1.00E00 chemotaxis to arachidonic acid (GO:0034670) 1 0 .10 - < 0.01 1.00E00 1.00E00 cardiac cell fate determination (GO:0060913) 3 0 .30 - < 0.01 1.00E00 1.00E00 cardiac cell fate specification (GO:0060912) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of transformation of host cell by virus (GO:1904188) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of transformation of host cell by virus (GO:1904187) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of pyruvate dehydrogenase activity (GO:1904184) 2 0 .20 - < 0.01 1.00E00 1.00E00 alpha-beta T cell proliferation (GO:0046633) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of pyruvate dehydrogenase activity (GO:1904182) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of membrane depolarization (GO:1904181) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 negative regulation of membrane depolarization (GO:1904180) 4 0 .40 - < 0.01 1.00E00 1.00E00 error-prone translesion synthesis (GO:0042276) 6 0 .59 - < 0.01 1.00E00 1.00E00 error-free postreplication DNA repair (GO:0042275) 2 0 .20 - < 0.01 1.00E00 1.00E00 ribosomal small subunit biogenesis (GO:0042274) 70 0 6.92 - < 0.01 2.54E-03 7.53E-02 ribosomal large subunit biogenesis (GO:0042273) 68 0 6.72 - < 0.01 2.50E-03 7.47E-02 susceptibility to natural killer cell mediated cytotoxicity (GO:0042271) 3 0 .30 - < 0.01 1.00E00 1.00E00 protection from natural killer cell mediated cytotoxicity (GO:0042270) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of meiosis I (GO:0060903) 4 0 .40 - < 0.01 1.00E00 1.00E00 embryonic camera-type eye formation (GO:0060900) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of bleb assembly (GO:1904172) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of bleb assembly (GO:1904171) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of bleb assembly (GO:1904170) 3 0 .30 - < 0.01 1.00E00 1.00E00 interneuron axon guidance (GO:0097376) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-asparagine hydroxylation (GO:0042265) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-aspartic acid hydroxylation (GO:0042264) 2 0 .20 - < 0.01 1.00E00 1.00E00 retinoic acid catabolic process (GO:0034653) 2 0 .20 - < 0.01 1.00E00 1.00E00 DNA protection (GO:0042262) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein O-GlcNAcylation via threonine (GO:0097370) 1 0 .10 - < 0.01 1.00E00 1.00E00 cortisol biosynthetic process (GO:0034651) 1 0 .10 - < 0.01 1.00E00 1.00E00 cortisol metabolic process (GO:0034650) 2 0 .20 - < 0.01 1.00E00 1.00E00 optic placode formation involved in camera-type eye formation (GO:0046619) 2 0 .20 - < 0.01 1.00E00 1.00E00 drug export (GO:0046618) 2 0 .20 - < 0.01 1.00E00 1.00E00 DNA synthesis involved in UV-damage excision repair (GO:1904161) 2 0 .20 - < 0.01 1.00E00 1.00E00 mature ribosome assembly (GO:0042256) 6 0 .59 - < 0.01 1.00E00 1.00E00 ribosome assembly (GO:0042255) 60 0 5.93 - < 0.01 5.70E-03 1.39E-01 mitochondrion migration along actin filament (GO:0034642) 1 0 .10 - < 0.01 1.00E00 1.00E00 establishment of mitochondrion localization by microtubule attachment (GO:0034640) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of retrograde protein transport, ER to cytosol (GO:1904154) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic centrosome separation (GO:0046604) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of mitotic centrosome separation (GO:0046602) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of centriole replication (GO:0046601) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of centriole replication (GO:0046600) 6 0 .59 - < 0.01 1.00E00 1.00E00 establishment of planar polarity of embryonic epithelium (GO:0042249) 4 0 .40 - < 0.01 1.00E00 1.00E00 protein localization to heterochromatin (GO:0097355) 2 0 .20 - < 0.01 1.00E00 1.00E00 establishment of planar polarity of follicular epithelium (GO:0042247) 1 0 .10 - < 0.01 1.00E00 1.00E00 prenylation (GO:0097354) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 RNA repair (GO:0042245) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of meiotic cell cycle process involved in oocyte maturation (GO:1904145) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of alkaline phosphatase activity (GO:0010694) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of microglial cell migration (GO:1904140) 1 0 .10 - < 0.01 1.00E00 1.00E00 'de novo' NAD biosynthetic process (GO:0034627) 3 0 .30 - < 0.01 1.00E00 1.00E00 fatty acid elongation, polyunsaturated fatty acid (GO:0034626) 7 0 .69 - < 0.01 1.00E00 1.00E00 ripoptosome assembly (GO:0097343) 2 0 .20 - < 0.01 1.00E00 1.00E00 fatty acid elongation, monounsaturated fatty acid (GO:0034625) 7 0 .69 - < 0.01 1.00E00 1.00E00 nuclear fragmentation involved in apoptotic nuclear change (GO:0030264) 1 0 .10 - < 0.01 1.00E00 1.00E00 apoptotic chromosome condensation (GO:0030263) 4 0 .40 - < 0.01 1.00E00 1.00E00 apoptotic nuclear changes (GO:0030262) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 chromosome condensation (GO:0030261) 28 0 2.77 - < 0.01 1.73E-01 9.69E-01 growth hormone secretion (GO:0030252) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of otic vesicle morphogenesis (GO:1904120) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to antineoplastic agent (GO:0097327) 1 0 .10 - < 0.01 1.00E00 1.00E00 melanocyte adhesion (GO:0097326) 1 0 .10 - < 0.01 1.00E00 1.00E00 melanocyte migration (GO:0097324) 2 0 .20 - < 0.01 1.00E00 1.00E00 B cell adhesion (GO:0097323) 1 0 .10 - < 0.01 1.00E00 1.00E00 terpene metabolic process (GO:0042214) 2 0 .20 - < 0.01 1.00E00 1.00E00 plasma membrane tubulation (GO:0097320) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 autophagy of peroxisome (GO:0030242) 5 0 .49 - < 0.01 1.00E00 1.00E00 skeletal muscle myosin thick filament assembly (GO:0030241) 2 0 .20 - < 0.01 1.00E00 1.00E00 skeletal muscle thin filament assembly (GO:0030240) 4 0 .40 - < 0.01 1.00E00 1.00E00 ectodermal cell differentiation (GO:0010668) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of otic vesicle morphogenesis (GO:1904118) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to vasopressin (GO:1904117) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to vasopressin (GO:1904116) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of muscle filament sliding (GO:1904113) 1 0 .10 - < 0.01 1.00E00 1.00E00 maternal determination of anterior/posterior axis, embryo (GO:0008358) 3 0 .30 - < 0.01 1.00E00 1.00E00 asymmetric cell division (GO:0008356) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 L-histidine transmembrane export from vacuole (GO:0089708) 1 0 .10 - < 0.01 1.00E00 1.00E00 olfactory learning (GO:0008355) 2 0 .20 - < 0.01 1.00E00 1.00E00 cap2 mRNA methylation (GO:0097310) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein kinase D signaling (GO:0089700) 2 0 .20 - < 0.01 1.00E00 1.00E00 female sex determination (GO:0030237) 1 0 .10 - < 0.01 1.00E00 1.00E00 cardiac muscle cell apoptotic process (GO:0010659) 5 0 .49 - < 0.01 1.00E00 1.00E00 striated muscle cell apoptotic process (GO:0010658) 5 0 .49 - < 0.01 1.00E00 1.00E00 protein localization to ciliary inversin compartment (GO:1904108) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cell communication by chemical coupling (GO:0010652) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cell communication by electrical coupling (GO:0010651) 1 0 .10 - < 0.01 1.00E00 1.00E00 cap1 mRNA methylation (GO:0097309) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of protein O-linked glycosylation (GO:1904100) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of cell communication by electrical coupling (GO:0010650) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein to membrane docking (GO:0022615) 4 0 .40 - < 0.01 1.00E00 1.00E00 membrane to membrane docking (GO:0022614) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cell communication by chemical coupling (GO:0010645) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell communication by electrical coupling (GO:0010644) 7 0 .69 - < 0.01 1.00E00 1.00E00 cell communication by chemical coupling (GO:0010643) 2 0 .20 - < 0.01 1.00E00 1.00E00 histone mRNA metabolic process (GO:0008334) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 mammalian oogenesis stage (GO:0022605) 4 0 .40 - < 0.01 1.00E00 1.00E00 heparin catabolic process (GO:0030211) 1 0 .10 - < 0.01 1.00E00 1.00E00 menstrual cycle phase (GO:0022601) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial fusion (GO:0010636) 4 0 .40 - < 0.01 1.00E00 1.00E00 closure of optic fissure (GO:0061386) 2 0 .20 - < 0.01 1.00E00 1.00E00 dermatan sulfate catabolic process (GO:0030209) 1 0 .10 - < 0.01 1.00E00 1.00E00 dermatan sulfate biosynthetic process (GO:0030208) 3 0 .30 - < 0.01 1.00E00 1.00E00 dermatan sulfate metabolic process (GO:0030205) 5 0 .49 - < 0.01 1.00E00 1.00E00 G2/MI transition of meiotic cell cycle (GO:0008315) 2 0 .20 - < 0.01 1.00E00 1.00E00 mammillary axonal complex development (GO:0061373) 1 0 .10 - < 0.01 1.00E00 1.00E00 testosterone biosynthetic process (GO:0061370) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac muscle adaptation (GO:0010616) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle adaptation (GO:0010615) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of testicular blood vessel morphogenesis (GO:0061369) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle adaptation (GO:0010612) 8 0 .79 - < 0.01 1.00E00 1.00E00 behavioral response to formalin induced pain (GO:0061368) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of mRNA stability involved in response to stress (GO:0010610) 2 0 .20 - < 0.01 1.00E00 1.00E00 behavioral response to chemical pain (GO:0061366) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of microvillus assembly (GO:1903697) 1 0 .10 - < 0.01 1.00E00 1.00E00 isoprenoid catabolic process (GO:0008300) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of wound healing, spreading of epidermal cells (GO:1903691) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of wound healing, spreading of epidermal cells (GO:1903690) 4 0 .40 - < 0.01 1.00E00 1.00E00 mRNA localization resulting in posttranscriptional regulation of gene expression (GO:0010609) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of cytoplasmic mRNA processing body assembly (GO:0010607) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cytoplasmic mRNA processing body assembly (GO:0010606) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of cytoplasmic mRNA processing body assembly (GO:0010603) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of wound healing, spreading of epidermal cells (GO:1903689) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of Wnt protein secretion (GO:0061357) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of Wnt protein secretion (GO:0061356) 3 0 .30 - < 0.01 1.00E00 1.00E00 Wnt protein secretion (GO:0061355) 2 0 .20 - < 0.01 1.00E00 1.00E00 pteridine metabolic process (GO:0019889) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cap-independent translational initiation (GO:1903679) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of cap-independent translational initiation (GO:1903677) 3 0 .30 - < 0.01 1.00E00 1.00E00 planar cell polarity pathway involved in heart morphogenesis (GO:0061346) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cap-dependent translational initiation (GO:1903676) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cap-dependent translational initiation (GO:1903674) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitotic cleavage furrow formation (GO:1903673) 1 0 .10 - < 0.01 1.00E00 1.00E00 non-canonical Wnt signaling pathway involved in heart development (GO:0061341) 1 0 .10 - < 0.01 1.00E00 1.00E00 lysine biosynthetic process via aminoadipic acid (GO:0019878) 1 0 .10 - < 0.01 1.00E00 1.00E00 establishment or maintenance of monopolar cell polarity (GO:0061339) 23 0 2.27 - < 0.01 2.61E-01 1.00E00 behavioral response to nicotine (GO:0035095) 4 0 .40 - < 0.01 1.00E00 1.00E00 spermatogenesis, exchange of chromosomal proteins (GO:0035093) 4 0 .40 - < 0.01 1.00E00 1.00E00 sperm chromatin condensation (GO:0035092) 6 0 .59 - < 0.01 1.00E00 1.00E00 maintenance of apical/basal cell polarity (GO:0035090) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of complement-dependent cytotoxicity (GO:1903660) 4 0 .40 - < 0.01 1.00E00 1.00E00 establishment of apical/basal cell polarity (GO:0035089) 20 0 1.98 - < 0.01 2.51E-01 1.00E00 siRNA loading onto RISC involved in RNA interference (GO:0035087) 4 0 .40 - < 0.01 1.00E00 1.00E00 cell proliferation involved in outflow tract morphogenesis (GO:0061325) 2 0 .20 - < 0.01 1.00E00 1.00E00 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation (GO:0061324) 2 0 .20 - < 0.01 1.00E00 1.00E00 cell proliferation involved in heart morphogenesis (GO:0061323) 2 0 .20 - < 0.01 1.00E00 1.00E00 uracil metabolic process (GO:0019860) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cytoplasmic transport (GO:1903650) 3 0 .30 - < 0.01 1.00E00 1.00E00 thymine metabolic process (GO:0019859) 2 0 .20 - < 0.01 1.00E00 1.00E00 cytosine metabolic process (GO:0019858) 2 0 .20 - < 0.01 1.00E00 1.00E00 5-methylcytosine metabolic process (GO:0019857) 3 0 .30 - < 0.01 1.00E00 1.00E00 pyrimidine nucleobase biosynthetic process (GO:0019856) 6 0 .59 - < 0.01 1.00E00 1.00E00 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment (GO:0061317) 1 0 .10 - < 0.01 1.00E00 1.00E00 canonical Wnt signaling pathway involved in heart development (GO:0061316) 3 0 .30 - < 0.01 1.00E00 1.00E00 L-ascorbic acid biosynthetic process (GO:0019853) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of chaperone-mediated protein folding (GO:1903646) 2 0 .20 - < 0.01 1.00E00 1.00E00 L-ascorbic acid metabolic process (GO:0019852) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of chaperone-mediated protein folding (GO:1903645) 2 0 .20 - < 0.01 1.00E00 1.00E00 canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development (GO:0061310) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of gastrin-induced gastric acid secretion (GO:1903640) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of gastrin-induced gastric acid secretion (GO:1903639) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of protein insertion into mitochondrial outer membrane (GO:1903638) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein insertion into mitochondrial outer membrane (GO:1903636) 1 0 .10 - < 0.01 1.00E00 1.00E00 retinal blood vessel morphogenesis (GO:0061304) 4 0 .40 - < 0.01 1.00E00 1.00E00 cornea development in camera-type eye (GO:0061303) 5 0 .49 - < 0.01 1.00E00 1.00E00 smooth muscle cell-matrix adhesion (GO:0061302) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of aminoacyl-tRNA ligase activity (GO:1903632) 2 0 .20 - < 0.01 1.00E00 1.00E00 cerebellum vasculature morphogenesis (GO:0061301) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of aminoacyl-tRNA ligase activity (GO:1903630) 2 0 .20 - < 0.01 1.00E00 1.00E00 embryonic heart tube anterior/posterior pattern specification (GO:0035054) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of DNA catabolic process (GO:1903626) 6 0 .59 - < 0.01 1.00E00 1.00E00 protein localization to photoreceptor connecting cilium (GO:1903621) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of transdifferentiation (GO:1903620) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of transdifferentiation (GO:1903618) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of protein tyrosine phosphatase activity (GO:1903615) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of calcium-dependent ATPase activity (GO:1903612) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of calcium-dependent ATPase activity (GO:1903610) 1 0 .10 - < 0.01 1.00E00 1.00E00 sperm entry (GO:0035037) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of inward rectifier potassium channel activity (GO:1903609) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein localization to cytoplasmic stress granule (GO:1903608) 7 0 .69 - < 0.01 1.00E00 1.00E00 leading edge cell differentiation (GO:0035026) 2 0 .20 - < 0.01 1.00E00 1.00E00 quinolinate biosynthetic process (GO:0019805) 4 0 .40 - < 0.01 1.00E00 1.00E00 neural plate regionalization (GO:0060897) 4 0 .40 - < 0.01 1.00E00 1.00E00 neural plate pattern specification (GO:0060896) 6 0 .59 - < 0.01 1.00E00 1.00E00 neuronal signal transduction (GO:0023041) 3 0 .30 - < 0.01 1.00E00 1.00E00 semicircular canal fusion (GO:0060879) 1 0 .10 - < 0.01 1.00E00 1.00E00 semicircular canal formation (GO:0060876) 2 0 .20 - < 0.01 1.00E00 1.00E00 lateral semicircular canal development (GO:0060875) 1 0 .10 - < 0.01 1.00E00 1.00E00 anterior semicircular canal development (GO:0060873) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of centriole replication (GO:0046599) 20 0 1.98 - < 0.01 2.51E-01 1.00E00 termination of signal transduction (GO:0023021) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of calcium-dependent cell-cell adhesion (GO:0046587) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of calcium-dependent cell-cell adhesion (GO:0046586) 1 0 .10 - < 0.01 1.00E00 1.00E00 establishment of glial blood-brain barrier (GO:0060857) 2 0 .20 - < 0.01 1.00E00 1.00E00 branching involved in lymph vessel morphogenesis (GO:0060854) 3 0 .30 - < 0.01 1.00E00 1.00E00 Notch signaling pathway involved in arterial endothelial cell fate commitment (GO:0060853) 2 0 .20 - < 0.01 1.00E00 1.00E00 chondrocyte development involved in endochondral bone morphogenesis (GO:0003433) 7 0 .69 - < 0.01 1.00E00 1.00E00 growth plate cartilage chondrocyte development (GO:0003431) 5 0 .49 - < 0.01 1.00E00 1.00E00 growth plate cartilage chondrocyte growth (GO:0003430) 3 0 .30 - < 0.01 1.00E00 1.00E00 endothelial cell fate specification (GO:0060847) 2 0 .20 - < 0.01 1.00E00 1.00E00 blood vessel endothelial cell fate commitment (GO:0060846) 2 0 .20 - < 0.01 1.00E00 1.00E00 arterial endothelial cell fate commitment (GO:0060844) 2 0 .20 - < 0.01 1.00E00 1.00E00 growth plate cartilage morphogenesis (GO:0003422) 1 0 .10 - < 0.01 1.00E00 1.00E00 growth plate cartilage axis specification (GO:0003421) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of growth plate cartilage chondrocyte proliferation (GO:0003420) 3 0 .30 - < 0.01 1.00E00 1.00E00 lymphatic endothelial cell fate commitment (GO:0060838) 2 0 .20 - < 0.01 1.00E00 1.00E00 lymphatic endothelial cell differentiation (GO:0060836) 7 0 .69 - < 0.01 1.00E00 1.00E00 smoothened signaling pathway involved in dorsal/ventral neural tube patterning (GO:0060831) 6 0 .59 - < 0.01 1.00E00 1.00E00 ciliary receptor clustering involved in smoothened signaling pathway (GO:0060830) 4 0 .40 - < 0.01 1.00E00 1.00E00 growth plate cartilage chondrocyte proliferation (GO:0003419) 1 0 .10 - < 0.01 1.00E00 1.00E00 growth plate cartilage chondrocyte differentiation (GO:0003418) 8 0 .79 - < 0.01 1.00E00 1.00E00 chondrocyte hypertrophy (GO:0003415) 5 0 .49 - < 0.01 1.00E00 1.00E00 chondrocyte differentiation involved in endochondral bone morphogenesis (GO:0003413) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis (GO:0003412) 1 0 .10 - < 0.01 1.00E00 1.00E00 photoreceptor cell fate commitment (GO:0046552) 2 0 .20 - < 0.01 1.00E00 1.00E00 hydroxyproline transport (GO:0034589) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation (GO:0060829) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation (GO:0060827) 1 0 .10 - < 0.01 1.00E00 1.00E00 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation (GO:0060825) 1 0 .10 - < 0.01 1.00E00 1.00E00 inactivation of X chromosome by DNA methylation (GO:0060821) 2 0 .20 - < 0.01 1.00E00 1.00E00 inactivation of X chromosome by heterochromatin assembly (GO:0060820) 1 0 .10 - < 0.01 1.00E00 1.00E00 optic cup structural organization (GO:0003409) 1 0 .10 - < 0.01 1.00E00 1.00E00 optic cup formation involved in camera-type eye development (GO:0003408) 1 0 .10 - < 0.01 1.00E00 1.00E00 retinal pigment epithelium development (GO:0003406) 7 0 .69 - < 0.01 1.00E00 1.00E00 optic vesicle morphogenesis (GO:0003404) 1 0 .10 - < 0.01 1.00E00 1.00E00 planar cell polarity pathway involved in axis elongation (GO:0003402) 1 0 .10 - < 0.01 1.00E00 1.00E00 retinal cone cell development (GO:0046549) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of protein O-linked glycosylation (GO:1904098) 3 0 .30 - < 0.01 1.00E00 1.00E00 retinal rod cell development (GO:0046548) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 regulation of COPII vesicle coating (GO:0003400) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of autophagic cell death (GO:1904093) 4 0 .40 - < 0.01 1.00E00 1.00E00 development of secondary male sexual characteristics (GO:0046544) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of autophagic cell death (GO:1904092) 7 0 .69 - < 0.01 1.00E00 1.00E00 saliva secretion (GO:0046541) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of nucleus size (GO:0097298) 1 0 .10 - < 0.01 1.00E00 1.00E00 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (GO:0097296) 3 0 .30 - < 0.01 1.00E00 1.00E00 inactivation of X chromosome by genetic imprinting (GO:0060819) 2 0 .20 - < 0.01 1.00E00 1.00E00 renal phosphate ion absorption (GO:0097291) 1 0 .10 - < 0.01 1.00E00 1.00E00 ketone catabolic process (GO:0042182) 8 0 .79 - < 0.01 1.00E00 1.00E00 random inactivation of X chromosome (GO:0060816) 2 0 .20 - < 0.01 1.00E00 1.00E00 mesodermal to mesenchymal transition involved in gastrulation (GO:0060809) 1 0 .10 - < 0.01 1.00E00 1.00E00 immune complex formation (GO:0097281) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cell differentiation involved in embryonic placenta development (GO:0060806) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of Wnt signaling pathway by BMP signaling pathway (GO:0060804) 1 0 .10 - < 0.01 1.00E00 1.00E00 presynaptic active zone assembly (GO:1904071) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular urea homeostasis (GO:0097277) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular creatinine homeostasis (GO:0097276) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular ammonium homeostasis (GO:0097275) 1 0 .10 - < 0.01 1.00E00 1.00E00 urea homeostasis (GO:0097274) 2 0 .20 - < 0.01 1.00E00 1.00E00 creatinine homeostasis (GO:0097273) 3 0 .30 - < 0.01 1.00E00 1.00E00 ammonium homeostasis (GO:0097272) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial respiratory chain complex II assembly (GO:0034553) 4 0 .40 - < 0.01 1.00E00 1.00E00 respiratory chain complex II assembly (GO:0034552) 4 0 .40 - < 0.01 1.00E00 1.00E00 mitochondrial respiratory chain complex III assembly (GO:0034551) 8 0 .79 - < 0.01 1.00E00 1.00E00 sphinganine biosynthetic process (GO:0046511) 2 0 .20 - < 0.01 1.00E00 1.00E00 lipoprotein catabolic process (GO:0042159) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 omega-hydroxylase P450 pathway (GO:0097267) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cholangiocyte proliferation (GO:1904056) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of cholangiocyte proliferation (GO:1904054) 3 0 .30 - < 0.01 1.00E00 1.00E00 intracellular mRNA localization (GO:0008298) 10 0 .99 - < 0.01 1.00E00 1.00E00 positive regulation of spontaneous neurotransmitter secretion (GO:1904050) 1 0 .10 - < 0.01 1.00E00 1.00E00 S-adenosylmethionine metabolic process (GO:0046500) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 strand invasion (GO:0042148) 4 0 .40 - < 0.01 1.00E00 1.00E00 acetylcholine biosynthetic process (GO:0008292) 1 0 .10 - < 0.01 1.00E00 1.00E00 oligodendrocyte apoptotic process (GO:0097252) 2 0 .20 - < 0.01 1.00E00 1.00E00 vacuole fusion, non-autophagic (GO:0042144) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitochondrial respirasome assembly (GO:0097250) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of DNA-dependent DNA replication initiation (GO:0030174) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of spontaneous neurotransmitter secretion (GO:1904049) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of spontaneous neurotransmitter secretion (GO:1904048) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of vascular endothelial growth factor production (GO:1904046) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of lamellipodium assembly (GO:0010593) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of cystathionine beta-synthase activity (GO:1904042) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cystathionine beta-synthase activity (GO:1904041) 1 0 .10 - < 0.01 1.00E00 1.00E00 meiotic DNA double-strand break formation (GO:0042138) 3 0 .30 - < 0.01 1.00E00 1.00E00 sequestering of neurotransmitter (GO:0042137) 1 0 .10 - < 0.01 1.00E00 1.00E00 neurotransmitter biosynthetic process (GO:0042136) 5 0 .49 - < 0.01 1.00E00 1.00E00 chromosome attachment to the nuclear envelope (GO:0097240) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of t-SNARE clustering (GO:1904034) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of t-SNARE clustering (GO:1904032) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cyclin-dependent protein kinase activity (GO:1904031) 26 0 2.57 - < 0.01 1.65E-01 1.00E00 cellular response to methylglyoxal (GO:0097238) 2 0 .20 - < 0.01 1.00E00 1.00E00 nitrate metabolic process (GO:0042126) 4 0 .40 - < 0.01 1.00E00 1.00E00 sulfate transport (GO:0008272) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 response to vitamin B6 (GO:0034516) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell motility in response to calcium ion (GO:0097231) 1 0 .10 - < 0.01 1.00E00 1.00E00 pancreatic juice secretion (GO:0030157) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of glucose catabolic process to lactate via pyruvate (GO:1904025) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of glucose catabolic process to lactate via pyruvate (GO:1904024) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of glucose catabolic process to lactate via pyruvate (GO:1904023) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of nuclear cell cycle DNA replication (GO:0010571) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of G protein-coupled receptor internalization (GO:1904021) 1 0 .10 - < 0.01 1.00E00 1.00E00 monocyte activation (GO:0042117) 4 0 .40 - < 0.01 1.00E00 1.00E00 mitochondrial mRNA polyadenylation (GO:0097222) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to kinetochore (GO:0034501) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 cellular response to Thyroglobulin triiodothyronine (GO:1904017) 3 0 .30 - < 0.01 1.00E00 1.00E00 response to Thyroglobulin triiodothyronine (GO:1904016) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of glycoprotein biosynthetic process (GO:0010561) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 positive regulation of lysosomal membrane permeability (GO:0097214) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of lysosomal membrane permeability (GO:0097213) 3 0 .30 - < 0.01 1.00E00 1.00E00 lysosomal membrane organization (GO:0097212) 6 0 .59 - < 0.01 1.00E00 1.00E00 cellular response to gonadotropin-releasing hormone (GO:0097211) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of T cell homeostatic proliferation (GO:0042103) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to gonadotropin-releasing hormone (GO:0097210) 2 0 .20 - < 0.01 1.00E00 1.00E00 cellular response to monosodium glutamate (GO:1904009) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to monosodium glutamate (GO:1904008) 2 0 .20 - < 0.01 1.00E00 1.00E00 tRNA threonylcarbamoyladenosine modification (GO:0002949) 3 0 .30 - < 0.01 1.00E00 1.00E00 tRNA C5-cytosine methylation (GO:0002946) 2 0 .20 - < 0.01 1.00E00 1.00E00 tRNA dihydrouridine synthesis (GO:0002943) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of eating behavior (GO:1904000) 3 0 .30 - < 0.01 1.00E00 1.00E00 tRNA N2-guanine methylation (GO:0002940) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of transcription from RNA polymerase II promoter in response to stress (GO:0097201) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 satellite cell activation involved in skeletal muscle regeneration (GO:0014901) 2 0 .20 - < 0.01 1.00E00 1.00E00 muscle hyperplasia (GO:0014900) 1 0 .10 - < 0.01 1.00E00 1.00E00 tRNA N1-guanine methylation (GO:0002939) 2 0 .20 - < 0.01 1.00E00 1.00E00 desmosome organization (GO:0002934) 10 0 .99 - < 0.01 1.00E00 1.00E00 lipid hydroxylation (GO:0002933) 3 0 .30 - < 0.01 1.00E00 1.00E00 tendon sheath development (GO:0002932) 1 0 .10 - < 0.01 1.00E00 1.00E00 trabecular meshwork development (GO:0002930) 1 0 .10 - < 0.01 1.00E00 1.00E00 canonical Wnt signaling pathway involved in metanephric kidney development (GO:0061290) 2 0 .20 - < 0.01 1.00E00 1.00E00 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation (GO:0002926) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002925) 6 0 .59 - < 0.01 1.00E00 1.00E00 Wnt signaling pathway involved in kidney development (GO:0061289) 2 0 .20 - < 0.01 1.00E00 1.00E00 vasopressin secretion (GO:0030103) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of transposition, RNA-mediated (GO:0010526) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of transposition, RNA-mediated (GO:0010525) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of lymphocyte anergy (GO:0002913) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of reciprocal meiotic recombination (GO:0010520) 3 0 .30 - < 0.01 1.00E00 1.00E00 mineralocorticoid metabolic process (GO:0008212) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of phosphatidylinositol biosynthetic process (GO:0010513) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of phosphatidylinositol biosynthetic process (GO:0010512) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of phosphatidylinositol biosynthetic process (GO:0010511) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of autophagy of mitochondrion (GO:1903599) 8 0 .79 - < 0.01 1.00E00 1.00E00 C21-steroid hormone metabolic process (GO:0008207) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 positive regulation of gap junction assembly (GO:1903598) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) 4 0 .40 - < 0.01 1.00E00 1.00E00 bile acid metabolic process (GO:0008206) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 positive regulation of histamine secretion by mast cell (GO:1903595) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of histamine secretion by mast cell (GO:1903593) 3 0 .30 - < 0.01 1.00E00 1.00E00 RNA secondary structure unwinding (GO:0010501) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of histone deubiquitination (GO:1903586) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of histone deubiquitination (GO:1903584) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of protein kinase D signaling (GO:1903572) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein kinase D signaling (GO:1903570) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to ciliary membrane (GO:1903569) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to ciliary membrane (GO:1903568) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of protein localization to ciliary membrane (GO:1903567) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to cilium (GO:1903566) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to cilium (GO:1903565) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of protein localization to cilium (GO:1903564) 8 0 .79 - < 0.01 1.00E00 1.00E00 pattern specification involved in mesonephros development (GO:0061227) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mesonephros development (GO:0061217) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of growth hormone activity (GO:1903547) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to photoreceptor outer segment (GO:1903546) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of exosomal secretion (GO:1903542) 3 0 .30 - < 0.01 1.00E00 1.00E00 establishment of protein localization to postsynaptic membrane (GO:1903540) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 regulation of isoprenoid metabolic process (GO:0019747) 3 0 .30 - < 0.01 1.00E00 1.00E00 cell proliferation involved in mesonephros development (GO:0061209) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein localization to postsynaptic membrane (GO:1903539) 30 0 2.97 - < 0.01 1.07E-01 8.98E-01 regulation of meiotic cell cycle process involved in oocyte maturation (GO:1903538) 3 0 .30 - < 0.01 1.00E00 1.00E00 paramesonephric duct development (GO:0061205) 2 0 .20 - < 0.01 1.00E00 1.00E00 nitrogen utilization (GO:0019740) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of membrane tubulation (GO:1903526) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of single strand break repair (GO:1903518) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of single strand break repair (GO:1903516) 2 0 .20 - < 0.01 1.00E00 1.00E00 calcium ion transport from cytosol to endoplasmic reticulum (GO:1903515) 2 0 .20 - < 0.01 1.00E00 1.00E00 release of sequestered calcium ion into cytosol by endoplasmic reticulum (GO:1903514) 6 0 .59 - < 0.01 1.00E00 1.00E00 Mo-molybdopterin cofactor metabolic process (GO:0019720) 6 0 .59 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum to cytosol transport (GO:1903513) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 phytanic acid metabolic process (GO:1903512) 1 0 .10 - < 0.01 1.00E00 1.00E00 apical constriction (GO:0003383) 5 0 .49 - < 0.01 1.00E00 1.00E00 sweat gland development (GO:0060792) 1 0 .10 - < 0.01 1.00E00 1.00E00 dynamin family protein polymerization involved in mitochondrial fission (GO:0003374) 8 0 .79 - < 0.01 1.00E00 1.00E00 dynamin family protein polymerization involved in membrane fission (GO:0003373) 8 0 .79 - < 0.01 1.00E00 1.00E00 cellular response to camptothecin (GO:0072757) 5 0 .49 - < 0.01 1.00E00 1.00E00 cellular response to benomyl (GO:0072755) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to rapamycin (GO:0072752) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular response to leptomycin B (GO:0072750) 2 0 .20 - < 0.01 1.00E00 1.00E00 hair follicle placode formation (GO:0060789) 5 0 .49 - < 0.01 1.00E00 1.00E00 ectodermal placode formation (GO:0060788) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 regulation of apoptosis involved in tissue homeostasis (GO:0060785) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cell proliferation involved in tissue homeostasis (GO:0060784) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell-matrix adhesion involved in ameboidal cell migration (GO:0003366) 2 0 .20 - < 0.01 1.00E00 1.00E00 lamellipodium assembly involved in ameboidal cell migration (GO:0003363) 1 0 .10 - < 0.01 1.00E00 1.00E00 brainstem development (GO:0003360) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to cytochalasin B (GO:0072749) 1 0 .10 - < 0.01 1.00E00 1.00E00 noradrenergic neuron development (GO:0003358) 1 0 .10 - < 0.01 1.00E00 1.00E00 noradrenergic neuron differentiation (GO:0003357) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of cilium beat frequency (GO:0003356) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 epithelial cilium movement involved in extracellular fluid movement (GO:0003351) 28 0 2.77 - < 0.01 1.73E-01 9.69E-01 S-adenosylmethioninamine metabolic process (GO:0046499) 1 0 .10 - < 0.01 1.00E00 1.00E00 pulmonary myocardium development (GO:0003350) 1 0 .10 - < 0.01 1.00E00 1.00E00 S-adenosylhomocysteine metabolic process (GO:0046498) 5 0 .49 - < 0.01 1.00E00 1.00E00 cellular response to diamide (GO:0072738) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to diamide (GO:0072737) 2 0 .20 - < 0.01 1.00E00 1.00E00 L-methylmalonyl-CoA metabolic process (GO:0046491) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to staurosporine (GO:0072734) 3 0 .30 - < 0.01 1.00E00 1.00E00 isopentenyl diphosphate metabolic process (GO:0046490) 5 0 .49 - < 0.01 1.00E00 1.00E00 response to staurosporine (GO:0072733) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of epithelial cell proliferation involved in prostate gland development (GO:0060769) 2 0 .20 - < 0.01 1.00E00 1.00E00 epithelial cell proliferation involved in prostate gland development (GO:0060767) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell-cell signaling involved in mammary gland development (GO:0060764) 2 0 .20 - < 0.01 1.00E00 1.00E00 epicardium-derived cardiac endothelial cell differentiation (GO:0003349) 2 0 .20 - < 0.01 1.00E00 1.00E00 epicardial cell to mesenchymal cell transition (GO:0003347) 3 0 .30 - < 0.01 1.00E00 1.00E00 proepicardium cell migration involved in pericardium morphogenesis (GO:0003345) 1 0 .10 - < 0.01 1.00E00 1.00E00 septum transversum development (GO:0003343) 1 0 .10 - < 0.01 1.00E00 1.00E00 proepicardium development (GO:0003342) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003340) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to dithiothreitol (GO:0072721) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to dithiothreitol (GO:0072720) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339) 3 0 .30 - < 0.01 1.00E00 1.00E00 epithelial cell proliferation involved in mammary gland duct elongation (GO:0060750) 3 0 .30 - < 0.01 1.00E00 1.00E00 mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337) 3 0 .30 - < 0.01 1.00E00 1.00E00 corneocyte development (GO:0003335) 2 0 .20 - < 0.01 1.00E00 1.00E00 keratinocyte development (GO:0003334) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 positive regulation of extracellular matrix constituent secretion (GO:0003331) 4 0 .40 - < 0.01 1.00E00 1.00E00 glycosylceramide catabolic process (GO:0046477) 6 0 .59 - < 0.01 1.00E00 1.00E00 glycosylceramide biosynthetic process (GO:0046476) 7 0 .69 - < 0.01 1.00E00 1.00E00 cellular response to actinomycin D (GO:0072717) 3 0 .30 - < 0.01 1.00E00 1.00E00 response to actinomycin D (GO:0072716) 4 0 .40 - < 0.01 1.00E00 1.00E00 cellular response to hydroxyurea (GO:0072711) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 response to hydroxyurea (GO:0072710) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 tertiary branching involved in mammary gland duct morphogenesis (GO:0060748) 3 0 .30 - < 0.01 1.00E00 1.00E00 parental behavior (GO:0060746) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 mammary gland branching involved in pregnancy (GO:0060745) 7 0 .69 - < 0.01 1.00E00 1.00E00 epithelial cell maturation involved in prostate gland development (GO:0060743) 2 0 .20 - < 0.01 1.00E00 1.00E00 type B pancreatic cell development (GO:0003323) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 pancreatic A cell development (GO:0003322) 1 0 .10 - < 0.01 1.00E00 1.00E00 dolichyl diphosphate metabolic process (GO:0046465) 3 0 .30 - < 0.01 1.00E00 1.00E00 cellular response to mercaptoethanol (GO:0072705) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to mercaptoethanol (GO:0072704) 1 0 .10 - < 0.01 1.00E00 1.00E00 early endosome to Golgi transport (GO:0034498) 8 0 .79 - < 0.01 1.00E00 1.00E00 mesenchymal-epithelial cell signaling involved in prostate gland development (GO:0060739) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of eIF2 alpha phosphorylation by dsRNA (GO:0060735) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation (GO:0060734) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of intestinal epithelial structure maintenance (GO:0060731) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of intestinal epithelial structure maintenance (GO:0060730) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell migration to the midline involved in heart development (GO:0003318) 1 0 .10 - < 0.01 1.00E00 1.00E00 short-chain fatty acid metabolic process (GO:0046459) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 pancreatic D cell differentiation (GO:0003311) 1 0 .10 - < 0.01 1.00E00 1.00E00 hexadecanal metabolic process (GO:0046458) 1 0 .10 - < 0.01 1.00E00 1.00E00 pancreatic A cell differentiation (GO:0003310) 4 0 .40 - < 0.01 1.00E00 1.00E00 dihydrofolate metabolic process (GO:0046452) 2 0 .20 - < 0.01 1.00E00 1.00E00 type 2 immune response (GO:0042092) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 regulation of cell proliferation involved in embryonic placenta development (GO:0060723) 2 0 .20 - < 0.01 1.00E00 1.00E00 cell proliferation involved in embryonic placenta development (GO:0060722) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of spongiotrophoblast cell proliferation (GO:0060721) 2 0 .20 - < 0.01 1.00E00 1.00E00 type B pancreatic cell differentiation (GO:0003309) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 spongiotrophoblast cell proliferation (GO:0060720) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of Wnt signaling pathway involved in heart development (GO:0003308) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of Wnt signaling pathway involved in heart development (GO:0003307) 7 0 .69 - < 0.01 1.00E00 1.00E00 Wnt signaling pathway involved in heart development (GO:0003306) 4 0 .40 - < 0.01 1.00E00 1.00E00 creatinine metabolic process (GO:0046449) 1 0 .10 - < 0.01 1.00E00 1.00E00 FMN metabolic process (GO:0046444) 1 0 .10 - < 0.01 1.00E00 1.00E00 FAD metabolic process (GO:0046443) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone H3-K36 trimethylation (GO:0097198) 3 0 .30 - < 0.01 1.00E00 1.00E00 L-lysine metabolic process (GO:0046440) 1 0 .10 - < 0.01 1.00E00 1.00E00 phosphatidylglycerol catabolic process (GO:0034478) 2 0 .20 - < 0.01 1.00E00 1.00E00 U6 snRNA 3'-end processing (GO:0034477) 2 0 .20 - < 0.01 1.00E00 1.00E00 U5 snRNA 3'-end processing (GO:0034476) 3 0 .30 - < 0.01 1.00E00 1.00E00 U4 snRNA 3'-end processing (GO:0034475) 7 0 .69 - < 0.01 1.00E00 1.00E00 U2 snRNA 3'-end processing (GO:0034474) 1 0 .10 - < 0.01 1.00E00 1.00E00 U1 snRNA 3'-end processing (GO:0034473) 3 0 .30 - < 0.01 1.00E00 1.00E00 snRNA 3'-end processing (GO:0034472) 19 0 1.88 - < 0.01 4.08E-01 1.00E00 cardiac muscle hypertrophy in response to stress (GO:0014898) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 smooth muscle hypertrophy (GO:0014895) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to denervation involved in regulation of muscle adaptation (GO:0014894) 3 0 .30 - < 0.01 1.00E00 1.00E00 L-cysteine metabolic process (GO:0046439) 3 0 .30 - < 0.01 1.00E00 1.00E00 D-amino acid biosynthetic process (GO:0046437) 1 0 .10 - < 0.01 1.00E00 1.00E00 dentin mineralization (GO:0097188) 1 0 .10 - < 0.01 1.00E00 1.00E00 dentinogenesis (GO:0097187) 5 0 .49 - < 0.01 1.00E00 1.00E00 germ-line stem cell division (GO:0042078) 4 0 .40 - < 0.01 1.00E00 1.00E00 cellular response to azide (GO:0097185) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to azide (GO:0097184) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell migration involved in gastrulation (GO:0042074) 9 0 .89 - < 0.01 1.00E00 1.00E00 glycogen cell differentiation involved in embryonic placenta development (GO:0060709) 1 0 .10 - < 0.01 1.00E00 1.00E00 90S preribosome assembly (GO:0034463) 1 0 .10 - < 0.01 1.00E00 1.00E00 small-subunit processome assembly (GO:0034462) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of endoribonuclease activity (GO:0060702) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of ribonuclease activity (GO:0060701) 2 0 .20 - < 0.01 1.00E00 1.00E00 cardiac muscle adaptation (GO:0014887) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 transition between slow and fast fiber (GO:0014886) 2 0 .20 - < 0.01 1.00E00 1.00E00 transition between fast and slow fiber (GO:0014883) 8 0 .79 - < 0.01 1.00E00 1.00E00 epoxide metabolic process (GO:0097176) 4 0 .40 - < 0.01 1.00E00 1.00E00 response to electrical stimulus involved in regulation of muscle adaptation (GO:0014878) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to muscle inactivity involved in regulation of muscle adaptation (GO:0014877) 3 0 .30 - < 0.01 1.00E00 1.00E00 response to injury involved in regulation of muscle adaptation (GO:0014876) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to stimulus involved in regulation of muscle adaptation (GO:0014874) 9 0 .89 - < 0.01 1.00E00 1.00E00 response to muscle activity involved in regulation of muscle adaptation (GO:0014873) 4 0 .40 - < 0.01 1.00E00 1.00E00 response to muscle inactivity (GO:0014870) 3 0 .30 - < 0.01 1.00E00 1.00E00 D-amino acid metabolic process (GO:0046416) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of epidermal growth factor receptor signaling pathway (GO:0042059) 24 0 2.37 - < 0.01 1.63E-01 1.00E00 circadian regulation of translation (GO:0097167) 4 0 .40 - < 0.01 1.00E00 1.00E00 negative regulation of plasma lipoprotein oxidation (GO:0034445) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of plasma lipoprotein oxidation (GO:0034444) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of lipoprotein oxidation (GO:0034443) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of lipoprotein oxidation (GO:0034442) 1 0 .10 - < 0.01 1.00E00 1.00E00 skeletal myofibril assembly (GO:0014866) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle contraction by chemo-mechanical energy conversion (GO:0014862) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of central B cell tolerance induction (GO:0002897) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of central B cell tolerance induction (GO:0002895) 1 0 .10 - < 0.01 1.00E00 1.00E00 olfactory behavior (GO:0042048) 7 0 .69 - < 0.01 1.00E00 1.00E00 fasciculation of motor neuron axon (GO:0097156) 1 0 .10 - < 0.01 1.00E00 1.00E00 fasciculation of sensory neuron axon (GO:0097155) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of inhibitory postsynaptic potential (GO:0097151) 7 0 .69 - < 0.01 1.00E00 1.00E00 metal incorporation into metallo-molybdopterin complex (GO:0042040) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of skeletal muscle cell proliferation (GO:0014859) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of skeletal muscle cell proliferation (GO:0014858) 4 0 .40 - < 0.01 1.00E00 1.00E00 skeletal muscle cell proliferation (GO:0014856) 2 0 .20 - < 0.01 1.00E00 1.00E00 response to inactivity (GO:0014854) 3 0 .30 - < 0.01 1.00E00 1.00E00 insulin processing (GO:0030070) 2 0 .20 - < 0.01 1.00E00 1.00E00 proteasomal ubiquitin-independent protein catabolic process (GO:0010499) 22 0 2.18 - < 0.01 2.56E-01 1.00E00 positive regulation of chronic inflammatory response to non-antigenic stimulus (GO:0002882) 1 0 .10 - < 0.01 1.00E00 1.00E00 peptidyl-histidine methylation, to form tele-methylhistidine (GO:0042038) 1 0 .10 - < 0.01 1.00E00 1.00E00 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' (GO:0034427) 10 0 .99 - < 0.01 1.00E00 1.00E00 post-translational protein acetylation (GO:0034421) 3 0 .30 - < 0.01 1.00E00 1.00E00 ureter smooth muscle contraction (GO:0014849) 2 0 .20 - < 0.01 1.00E00 1.00E00 urinary tract smooth muscle contraction (GO:0014848) 10 0 .99 - < 0.01 1.00E00 1.00E00 growth factor dependent regulation of skeletal muscle satellite cell proliferation (GO:0014843) 1 0 .10 - < 0.01 1.00E00 1.00E00 skeletal muscle satellite cell proliferation (GO:0014841) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of acute inflammatory response to non-antigenic stimulus (GO:0002879) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of acute inflammatory response to non-antigenic stimulus (GO:0002877) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of chronic inflammatory response to antigenic stimulus (GO:0002876) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of epidermal cell division (GO:0010482) 1 0 .10 - < 0.01 1.00E00 1.00E00 DNA endoreduplication (GO:0042023) 1 0 .10 - < 0.01 1.00E00 1.00E00 tRNA 3'-trailer cleavage, endonucleolytic (GO:0034414) 1 0 .10 - < 0.01 1.00E00 1.00E00 myoblast differentiation involved in skeletal muscle regeneration (GO:0014835) 3 0 .30 - < 0.01 1.00E00 1.00E00 urinary bladder smooth muscle contraction (GO:0014832) 8 0 .79 - < 0.01 1.00E00 1.00E00 regulation of gastrulation (GO:0010470) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex (GO:0034402) 2 0 .20 - < 0.01 1.00E00 1.00E00 muscle filament sliding (GO:0030049) 4 0 .40 - < 0.01 1.00E00 1.00E00 actin modification (GO:0030047) 2 0 .20 - < 0.01 1.00E00 1.00E00 intestine smooth muscle contraction (GO:0014827) 2 0 .20 - < 0.01 1.00E00 1.00E00 vein smooth muscle contraction (GO:0014826) 3 0 .30 - < 0.01 1.00E00 1.00E00 actin filament fragmentation (GO:0030043) 4 0 .40 - < 0.01 1.00E00 1.00E00 detection of wounding (GO:0014822) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of T cell mediated cytotoxicity directed against tumor cell target (GO:0002854) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of T cell mediated cytotoxicity directed against tumor cell target (GO:0002853) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of T cell mediated cytotoxicity directed against tumor cell target (GO:0002852) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of peripheral T cell tolerance induction (GO:0002851) 1 0 .10 - < 0.01 1.00E00 1.00E00 AMPA glutamate receptor clustering (GO:0097113) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of translational initiation by iron (GO:0045994) 2 0 .20 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum-Golgi intermediate compartment organization (GO:0097111) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of embryonic development (GO:0045992) 2 0 .20 - < 0.01 1.00E00 1.00E00 carbon catabolite activation of transcription (GO:0045991) 4 0 .40 - < 0.01 1.00E00 1.00E00 carbon catabolite regulation of transcription (GO:0045990) 4 0 .40 - < 0.01 1.00E00 1.00E00 translocation of peptides or proteins into host (GO:0042000) 1 0 .10 - < 0.01 1.00E00 1.00E00 skeletal muscle satellite cell differentiation (GO:0014816) 5 0 .49 - < 0.01 1.00E00 1.00E00 microvillar actin bundle assembly (GO:0030034) 1 0 .10 - < 0.01 1.00E00 1.00E00 skeletal muscle satellite cell commitment (GO:0014813) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of peripheral T cell tolerance induction (GO:0002849) 1 0 .10 - < 0.01 1.00E00 1.00E00 centriole-centriole cohesion (GO:0010457) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 positive regulation of tolerance induction to tumor cell (GO:0002845) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone H3-K36 methylation (GO:0010452) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of tolerance induction to tumor cell (GO:0002843) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of T cell mediated immune response to tumor cell (GO:0002842) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of T cell mediated immune response to tumor cell (GO:0002841) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of T cell mediated immune response to tumor cell (GO:0002840) 7 0 .69 - < 0.01 1.00E00 1.00E00 endothelial tip cell fate specification (GO:0097102) 1 0 .10 - < 0.01 1.00E00 1.00E00 blood vessel endothelial cell fate specification (GO:0097101) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion (GO:0014809) 2 0 .20 - < 0.01 1.00E00 1.00E00 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0014808) 5 0 .49 - < 0.01 1.00E00 1.00E00 protein maturation by protein folding (GO:0022417) 5 0 .49 - < 0.01 1.00E00 1.00E00 cellular manganese ion homeostasis (GO:0030026) 2 0 .20 - < 0.01 1.00E00 1.00E00 smooth muscle hyperplasia (GO:0014806) 1 0 .10 - < 0.01 1.00E00 1.00E00 smooth muscle adaptation (GO:0014805) 2 0 .20 - < 0.01 1.00E00 1.00E00 circadian sleep/wake cycle process (GO:0022410) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to alkaline pH (GO:0010446) 1 0 .10 - < 0.01 1.00E00 1.00E00 fungiform papilla formation (GO:0061198) 3 0 .30 - < 0.01 1.00E00 1.00E00 fungiform papilla morphogenesis (GO:0061197) 5 0 .49 - < 0.01 1.00E00 1.00E00 fungiform papilla development (GO:0061196) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of mitotic cell cycle, embryonic (GO:0045976) 2 0 .20 - < 0.01 1.00E00 1.00E00 taste bud development (GO:0061193) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of translation, ncRNA-mediated (GO:0045975) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell cycle phase (GO:0022403) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 maintenance of cell polarity (GO:0030011) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 regulation of rhodopsin mediated signaling pathway (GO:0022400) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of ribosomal DNA heterochromatin assembly (GO:0061188) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of ribosomal DNA heterochromatin assembly (GO:0061187) 2 0 .20 - < 0.01 1.00E00 1.00E00 fatty acid omega-oxidation (GO:0010430) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of dermatome development (GO:0061185) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of dermatome development (GO:0061184) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of dermatome development (GO:0061183) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of complement activation, classical pathway (GO:0045960) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria (GO:0002816) 1 0 .10 - < 0.01 1.00E00 1.00E00 DNA methylation on cytosine within a CG sequence (GO:0010424) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of insulin secretion involved in cellular response to glucose stimulus (GO:0061179) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 hydrogen peroxide-mediated programmed cell death (GO:0010421) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of complement activation, alternative pathway (GO:0045957) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic recombination (GO:0045951) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of mitotic recombination (GO:0045950) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of antibacterial peptide biosynthetic process (GO:0002808) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of antimicrobial peptide biosynthetic process (GO:0002807) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of antimicrobial peptide biosynthetic process (GO:0002805) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of antibacterial peptide production (GO:0002803) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of translational initiation (GO:0045948) 19 0 1.88 - < 0.01 4.08E-01 1.00E00 endoplasmic reticulum polarization (GO:0061163) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of transcription by RNA polymerase III (GO:0045945) 10 0 .99 - < 0.01 1.00E00 1.00E00 establishment of monopolar cell polarity (GO:0061162) 22 0 2.18 - < 0.01 2.56E-01 1.00E00 positive regulation of transcription by RNA polymerase I (GO:0045943) 23 0 2.27 - < 0.01 2.61E-01 1.00E00 positive regulation of mitotic cytokinesis (GO:1903490) 1 0 .10 - < 0.01 1.00E00 1.00E00 box H/ACA RNA metabolic process (GO:0033979) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of lactation (GO:1903489) 2 0 .20 - < 0.01 1.00E00 1.00E00 pulmonary artery morphogenesis (GO:0061156) 5 0 .49 - < 0.01 1.00E00 1.00E00 alkanesulfonate metabolic process (GO:0019694) 7 0 .69 - < 0.01 1.00E00 1.00E00 pulmonary artery endothelial tube morphogenesis (GO:0061155) 1 0 .10 - < 0.01 1.00E00 1.00E00 endothelial tube morphogenesis (GO:0061154) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 BMP signaling pathway involved in renal system segmentation (GO:0061151) 1 0 .10 - < 0.01 1.00E00 1.00E00 renal system segmentation (GO:0061150) 1 0 .10 - < 0.01 1.00E00 1.00E00 box C/D RNA metabolic process (GO:0033967) 3 0 .30 - < 0.01 1.00E00 1.00E00 neural plate anterior/posterior regionalization (GO:0021999) 3 0 .30 - < 0.01 1.00E00 1.00E00 neural plate mediolateral regionalization (GO:0021998) 1 0 .10 - < 0.01 1.00E00 1.00E00 neural plate axis specification (GO:0021997) 2 0 .20 - < 0.01 1.00E00 1.00E00 neuropore closure (GO:0021995) 2 0 .20 - < 0.01 1.00E00 1.00E00 initiation of neural tube closure (GO:0021993) 1 0 .10 - < 0.01 1.00E00 1.00E00 neural plate formation (GO:0021990) 1 0 .10 - < 0.01 1.00E00 1.00E00 BMP signaling pathway involved in ureter morphogenesis (GO:0061149) 1 0 .10 - < 0.01 1.00E00 1.00E00 lung smooth muscle development (GO:0061145) 2 0 .20 - < 0.01 1.00E00 1.00E00 glyceraldehyde-3-phosphate metabolic process (GO:0019682) 5 0 .49 - < 0.01 1.00E00 1.00E00 alveolar secondary septum development (GO:0061144) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of female receptivity (GO:0045925) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of female receptivity (GO:0045924) 7 0 .69 - < 0.01 1.00E00 1.00E00 lung ciliated cell differentiation (GO:0061141) 1 0 .10 - < 0.01 1.00E00 1.00E00 habenula development (GO:0021986) 3 0 .30 - < 0.01 1.00E00 1.00E00 NAD catabolic process (GO:0019677) 4 0 .40 - < 0.01 1.00E00 1.00E00 ammonia assimilation cycle (GO:0019676) 2 0 .20 - < 0.01 1.00E00 1.00E00 GDP-mannose metabolic process (GO:0019673) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic cell cycle DNA replication (GO:1903465) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mitotic cell cycle DNA replication (GO:1903463) 2 0 .20 - < 0.01 1.00E00 1.00E00 Okazaki fragment processing involved in mitotic DNA replication (GO:1903461) 1 0 .10 - < 0.01 1.00E00 1.00E00 corticospinal neuron axon guidance through spinal cord (GO:0021972) 1 0 .10 - < 0.01 1.00E00 1.00E00 lactate catabolic process (GO:1903457) 1 0 .10 - < 0.01 1.00E00 1.00E00 glucose catabolic process to lactate via pyruvate (GO:0019661) 1 0 .10 - < 0.01 1.00E00 1.00E00 glycolytic fermentation (GO:0019660) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of translational fidelity (GO:0045903) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of G1 to G0 transition (GO:1903452) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of G1 to G0 transition (GO:1903450) 1 0 .10 - < 0.01 1.00E00 1.00E00 corticospinal neuron axon guidance (GO:0021966) 2 0 .20 - < 0.01 1.00E00 1.00E00 spinal cord ventral commissure morphogenesis (GO:0021965) 1 0 .10 - < 0.01 1.00E00 1.00E00 glucose catabolic process to lactate (GO:0019659) 1 0 .10 - < 0.01 1.00E00 1.00E00 anterior commissure morphogenesis (GO:0021960) 5 0 .49 - < 0.01 1.00E00 1.00E00 lung proximal/distal axis specification (GO:0061115) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein transport from ciliary membrane to plasma membrane (GO:1903445) 3 0 .30 - < 0.01 1.00E00 1.00E00 branching involved in pancreas morphogenesis (GO:0061114) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of brown fat cell differentiation (GO:1903444) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein localization to ciliary membrane (GO:1903441) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 corticospinal tract morphogenesis (GO:0021957) 8 0 .79 - < 0.01 1.00E00 1.00E00 central nervous system interneuron axonogenesis (GO:0021956) 1 0 .10 - < 0.01 1.00E00 1.00E00 aerobic electron transport chain (GO:0019646) 47 0 4.65 - < 0.01 1.98E-02 3.42E-01 positive regulation of mitotic cytokinetic process (GO:1903438) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mitotic cytokinetic process (GO:1903436) 1 0 .10 - < 0.01 1.00E00 1.00E00 adrenal chromaffin cell differentiation (GO:0061104) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of constitutive secretory pathway (GO:1903434) 1 0 .10 - < 0.01 1.00E00 1.00E00 neuroendocrine cell differentiation (GO:0061101) 5 0 .49 - < 0.01 1.00E00 1.00E00 radial glia guided migration of Purkinje cell (GO:0021942) 5 0 .49 - < 0.01 1.00E00 1.00E00 protein localization to microtubule cytoskeleton (GO:0072698) 39 0 3.86 - < 0.01 4.60E-02 5.72E-01 negative regulation of cerebellar granule cell precursor proliferation (GO:0021941) 1 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to cell cortex (GO:0072697) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of DNA recombination at telomere (GO:0072695) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of synaptic vesicle recycling (GO:1903422) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein localization to endoplasmic reticulum tubular network (GO:1903420) 1 0 .10 - < 0.01 1.00E00 1.00E00 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation (GO:0021938) 2 0 .20 - < 0.01 1.00E00 1.00E00 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation (GO:0021937) 2 0 .20 - < 0.01 1.00E00 1.00E00 cerebellar granule cell precursor tangential migration (GO:0021935) 2 0 .20 - < 0.01 1.00E00 1.00E00 hindbrain tangential cell migration (GO:0021934) 2 0 .20 - < 0.01 1.00E00 1.00E00 urate catabolic process (GO:0019628) 1 0 .10 - < 0.01 1.00E00 1.00E00 cerebellar granule cell precursor proliferation (GO:0021930) 6 0 .59 - < 0.01 1.00E00 1.00E00 urea metabolic process (GO:0019627) 7 0 .69 - < 0.01 1.00E00 1.00E00 short-chain fatty acid catabolic process (GO:0019626) 5 0 .49 - < 0.01 1.00E00 1.00E00 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic (GO:0072684) 1 0 .10 - < 0.01 1.00E00 1.00E00 response to glycoside (GO:1903416) 1 0 .10 - < 0.01 1.00E00 1.00E00 muscle hypertrophy in response to stress (GO:0003299) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 atrial ventricular junction remodeling (GO:0003294) 1 0 .10 - < 0.01 1.00E00 1.00E00 cardiac septum cell differentiation (GO:0003292) 3 0 .30 - < 0.01 1.00E00 1.00E00 atrial septum secundum morphogenesis (GO:0003290) 1 0 .10 - < 0.01 1.00E00 1.00E00 cell proliferation in external granule layer (GO:0021924) 6 0 .59 - < 0.01 1.00E00 1.00E00 catechol-containing compound catabolic process (GO:0019614) 4 0 .40 - < 0.01 1.00E00 1.00E00 lamellipodium morphogenesis (GO:0072673) 7 0 .69 - < 0.01 1.00E00 1.00E00 protein localization to nuclear body (GO:1903405) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of renal phosphate excretion (GO:1903403) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of renal phosphate excretion (GO:1903402) 1 0 .10 - < 0.01 1.00E00 1.00E00 L-lysine transmembrane transport (GO:1903401) 3 0 .30 - < 0.01 1.00E00 1.00E00 L-arginine transmembrane transport (GO:1903400) 5 0 .49 - < 0.01 1.00E00 1.00E00 septum secundum development (GO:0003285) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning (GO:0021914) 2 0 .20 - < 0.01 1.00E00 1.00E00 2-oxobutyrate catabolic process (GO:0019606) 1 0 .10 - < 0.01 1.00E00 1.00E00 butyrate metabolic process (GO:0019605) 1 0 .10 - < 0.01 1.00E00 1.00E00 establishment of protein localization to peroxisome (GO:0072663) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 protein localization to peroxisome (GO:0072662) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 maintenance of protein location in plasma membrane (GO:0072660) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of endoribonuclease activity (GO:0060699) 3 0 .30 - < 0.01 1.00E00 1.00E00 chemosensory behavior (GO:0007635) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 negative regulation of cholesterol transporter activity (GO:0060695) 1 0 .10 - < 0.01 1.00E00 1.00E00 optokinetic behavior (GO:0007634) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cholesterol transporter activity (GO:0060694) 1 0 .10 - < 0.01 1.00E00 1.00E00 epithelial cell maturation involved in salivary gland development (GO:0060691) 1 0 .10 - < 0.01 1.00E00 1.00E00 jump response (GO:0007630) 1 0 .10 - < 0.01 1.00E00 1.00E00 epithelial cell differentiation involved in salivary gland development (GO:0060690) 2 0 .20 - < 0.01 1.00E00 1.00E00 apoptotic process involved in heart morphogenesis (GO:0003278) 1 0 .10 - < 0.01 1.00E00 1.00E00 smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation (GO:0003271) 1 0 .10 - < 0.01 1.00E00 1.00E00 forebrain-midbrain boundary formation (GO:0021905) 1 0 .10 - < 0.01 1.00E00 1.00E00 dorsal/ventral neural tube patterning (GO:0021904) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 commitment of neuronal cell to specific neuron type in forebrain (GO:0021902) 5 0 .49 - < 0.01 1.00E00 1.00E00 maintenance of protein location in membrane (GO:0072658) 3 0 .30 - < 0.01 1.00E00 1.00E00 maintenance of protein location in mitochondrion (GO:0072656) 5 0 .49 - < 0.01 1.00E00 1.00E00 cell differentiation involved in salivary gland development (GO:0060689) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of branching involved in prostate gland morphogenesis (GO:0060687) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of prostatic bud formation (GO:0060686) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of prostatic bud formation (GO:0060685) 4 0 .40 - < 0.01 1.00E00 1.00E00 grooming behavior (GO:0007625) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 epithelial-mesenchymal cell signaling (GO:0060684) 3 0 .30 - < 0.01 1.00E00 1.00E00 ultradian rhythm (GO:0007624) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling (GO:0060683) 1 0 .10 - < 0.01 1.00E00 1.00E00 primary ureteric bud growth (GO:0060682) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of female receptivity (GO:0007621) 3 0 .30 - < 0.01 1.00E00 1.00E00 branch elongation involved in ureteric bud branching (GO:0060681) 1 0 .10 - < 0.01 1.00E00 1.00E00 cardioblast migration (GO:0003260) 1 0 .10 - < 0.01 1.00E00 1.00E00 courtship behavior (GO:0007619) 5 0 .49 - < 0.01 1.00E00 1.00E00 dichotomous subdivision of terminal units involved in ureteric bud branching (GO:0060678) 1 0 .10 - < 0.01 1.00E00 1.00E00 ureteric bud elongation (GO:0060677) 4 0 .40 - < 0.01 1.00E00 1.00E00 ureteric bud formation (GO:0060676) 4 0 .40 - < 0.01 1.00E00 1.00E00 epithelial cell morphogenesis involved in placental branching (GO:0060672) 2 0 .20 - < 0.01 1.00E00 1.00E00 epithelial cell differentiation involved in embryonic placenta development (GO:0060671) 2 0 .20 - < 0.01 1.00E00 1.00E00 cardioblast anterior-lateral migration (GO:0003259) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation (GO:0003257) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of cell proliferation involved in heart valve morphogenesis (GO:0003251) 1 0 .10 - < 0.01 1.00E00 1.00E00 5-phosphoribose 1-diphosphate metabolic process (GO:0046391) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of phospholipid efflux (GO:1902999) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of phospholipid efflux (GO:1902995) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of phospholipid efflux (GO:1902994) 4 0 .40 - < 0.01 1.00E00 1.00E00 phototransduction, visible light (GO:0007603) 6 0 .59 - < 0.01 1.00E00 1.00E00 phototransduction (GO:0007602) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 submandibular salivary gland formation (GO:0060661) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitotic telomere maintenance via semi-conservative replication (GO:1902990) 3 0 .30 - < 0.01 1.00E00 1.00E00 post-embryonic cardiac muscle cell growth involved in heart morphogenesis (GO:0003247) 1 0 .10 - < 0.01 1.00E00 1.00E00 cardiac muscle tissue growth involved in heart morphogenesis (GO:0003245) 2 0 .20 - < 0.01 1.00E00 1.00E00 circumferential growth involved in left ventricle morphogenesis (GO:0003243) 1 0 .10 - < 0.01 1.00E00 1.00E00 deoxyribose phosphate biosynthetic process (GO:0046385) 10 0 .99 - < 0.01 1.00E00 1.00E00 CMP-N-acetylneuraminate metabolic process (GO:0046381) 2 0 .20 - < 0.01 1.00E00 1.00E00 N-acetylneuraminate biosynthetic process (GO:0046380) 1 0 .10 - < 0.01 1.00E00 1.00E00 nipple morphogenesis (GO:0060658) 1 0 .10 - < 0.01 1.00E00 1.00E00 DNA strand elongation involved in mitotic DNA replication (GO:1902983) 1 0 .10 - < 0.01 1.00E00 1.00E00 sinus venosus morphogenesis (GO:0003236) 1 0 .10 - < 0.01 1.00E00 1.00E00 sinus venosus development (GO:0003235) 1 0 .10 - < 0.01 1.00E00 1.00E00 extracellular polysaccharide metabolic process (GO:0046379) 2 0 .20 - < 0.01 1.00E00 1.00E00 L-arabinose metabolic process (GO:0046373) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitotic DNA replication termination (GO:1902979) 1 0 .10 - < 0.01 1.00E00 1.00E00 mitotic DNA replication preinitiation complex assembly (GO:1902977) 1 0 .10 - < 0.01 1.00E00 1.00E00 atrial cardiac muscle tissue development (GO:0003228) 5 0 .49 - < 0.01 1.00E00 1.00E00 right ventricular compact myocardium morphogenesis (GO:0003226) 1 0 .10 - < 0.01 1.00E00 1.00E00 ventricular compact myocardium morphogenesis (GO:0003223) 8 0 .79 - < 0.01 1.00E00 1.00E00 right ventricular cardiac muscle tissue morphogenesis (GO:0003221) 2 0 .20 - < 0.01 1.00E00 1.00E00 left ventricular cardiac muscle tissue morphogenesis (GO:0003220) 1 0 .10 - < 0.01 1.00E00 1.00E00 GDP-L-fucose metabolic process (GO:0046368) 3 0 .30 - < 0.01 1.00E00 1.00E00 monosaccharide catabolic process (GO:0046365) 21 0 2.08 - < 0.01 2.52E-01 1.00E00 2-oxobutyrate metabolic process (GO:0046361) 2 0 .20 - < 0.01 1.00E00 1.00E00 2-oxobutyrate biosynthetic process (GO:0046360) 1 0 .10 - < 0.01 1.00E00 1.00E00 telomere tethering at nuclear periphery (GO:0034398) 2 0 .20 - < 0.01 1.00E00 1.00E00 telomere localization (GO:0034397) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of transcription initiation from RNA polymerase II promoter (GO:0060633) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of meiosis I (GO:0060631) 5 0 .49 - < 0.01 1.00E00 1.00E00 cardiac left ventricle formation (GO:0003218) 1 0 .10 - < 0.01 1.00E00 1.00E00 butyrate catabolic process (GO:0046359) 1 0 .10 - < 0.01 1.00E00 1.00E00 cardiac atrium formation (GO:0003210) 2 0 .20 - < 0.01 1.00E00 1.00E00 acetyl-CoA catabolic process (GO:0046356) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial electron transport, NADH to ubiquinone (GO:1902958) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial electron transport, NADH to ubiquinone (GO:1902957) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial electron transport, NADH to ubiquinone (GO:1902956) 4 0 .40 - < 0.01 1.00E00 1.00E00 high-density lipoprotein particle assembly (GO:0034380) 6 0 .59 - < 0.01 1.00E00 1.00E00 regulation of chromosome condensation (GO:0060623) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of dendritic spine maintenance (GO:1902952) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of cholesterol import (GO:0060621) 1 0 .10 - < 0.01 1.00E00 1.00E00 amino sugar biosynthetic process (GO:0046349) 8 0 .79 - < 0.01 1.00E00 1.00E00 CDP-diacylglycerol metabolic process (GO:0046341) 4 0 .40 - < 0.01 1.00E00 1.00E00 diacylglycerol catabolic process (GO:0046340) 4 0 .40 - < 0.01 1.00E00 1.00E00 chylomicron assembly (GO:0034378) 2 0 .20 - < 0.01 1.00E00 1.00E00 high-density lipoprotein particle remodeling (GO:0034375) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 nipple development (GO:0060618) 1 0 .10 - < 0.01 1.00E00 1.00E00 mammary gland fat development (GO:0060611) 1 0 .10 - < 0.01 1.00E00 1.00E00 methyl-branched fatty acid metabolic process (GO:0097089) 3 0 .30 - < 0.01 1.00E00 1.00E00 plasma membrane selenite transport (GO:0097080) 1 0 .10 - < 0.01 1.00E00 1.00E00 glycerol biosynthetic process from pyruvate (GO:0046327) 2 0 .20 - < 0.01 1.00E00 1.00E00 'de novo' NAD biosynthetic process from tryptophan (GO:0034354) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of glial cell apoptotic process (GO:0034352) 3 0 .30 - < 0.01 1.00E00 1.00E00 response to thyroxine (GO:0097068) 1 0 .10 - < 0.01 1.00E00 1.00E00 anterior head development (GO:0097065) 5 0 .49 - < 0.01 1.00E00 1.00E00 ncRNA export from nucleus (GO:0097064) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of type III interferon production (GO:0034346) 1 0 .10 - < 0.01 1.00E00 1.00E00 dendritic spine maintenance (GO:0097062) 11 0 1.09 - < 0.01 6.14E-01 1.00E00 regulation of type III interferon production (GO:0034344) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of protein polyubiquitination (GO:1902916) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 positive regulation of neuroepithelial cell differentiation (GO:1902913) 1 0 .10 - < 0.01 1.00E00 1.00E00 alkanesulfonate biosynthetic process (GO:0046305) 1 0 .10 - < 0.01 1.00E00 1.00E00 selenocysteinyl-tRNA(Sec) biosynthetic process (GO:0097056) 1 0 .10 - < 0.01 1.00E00 1.00E00 RNA folding (GO:0034337) 1 0 .10 - < 0.01 1.00E00 1.00E00 L-kynurenine metabolic process (GO:0097052) 2 0 .20 - < 0.01 1.00E00 1.00E00 establishment of protein localization to endoplasmic reticulum membrane (GO:0097051) 3 0 .30 - < 0.01 1.00E00 1.00E00 type B pancreatic cell apoptotic process (GO:0097050) 3 0 .30 - < 0.01 1.00E00 1.00E00 adherens junction assembly (GO:0034333) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 regulation of antibacterial peptide production (GO:0002786) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of antimicrobial peptide production (GO:0002784) 4 0 .40 - < 0.01 1.00E00 1.00E00 phosphatidylserine exposure on blood platelet (GO:0097045) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of muscle adaptation (GO:0014745) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 negative regulation of muscle hyperplasia (GO:0014740) 2 0 .20 - < 0.01 1.00E00 1.00E00 Fc receptor mediated inhibitory signaling pathway (GO:0002774) 1 0 .10 - < 0.01 1.00E00 1.00E00 mesodermal cell migration (GO:0008078) 4 0 .40 - < 0.01 1.00E00 1.00E00 protein linear polyubiquitination (GO:0097039) 3 0 .30 - < 0.01 1.00E00 1.00E00 heme export (GO:0097037) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of plasma membrane sterol distribution (GO:0097036) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of Arp2/3 complex-mediated actin nucleation (GO:0034316) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315) 19 0 1.88 - < 0.01 4.08E-01 1.00E00 Arp2/3 complex-mediated actin nucleation (GO:0034314) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 primary alcohol catabolic process (GO:0034310) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of muscle atrophy (GO:0014737) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of muscle atrophy (GO:0014736) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of muscle atrophy (GO:0014735) 4 0 .40 - < 0.01 1.00E00 1.00E00 skeletal muscle hypertrophy (GO:0014734) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle adaptation (GO:0014733) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 skeletal muscle atrophy (GO:0014732) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of antimicrobial humoral response (GO:0002760) 5 0 .49 - < 0.01 1.00E00 1.00E00 primary alcohol biosynthetic process (GO:0034309) 2 0 .20 - < 0.01 1.00E00 1.00E00 establishment of blood-nerve barrier (GO:0008065) 3 0 .30 - < 0.01 1.00E00 1.00E00 dendritic cell dendrite assembly (GO:0097026) 1 0 .10 - < 0.01 1.00E00 1.00E00 Toll signaling pathway (GO:0008063) 6 0 .59 - < 0.01 1.00E00 1.00E00 lymphocyte migration into lymph node (GO:0097022) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of the force of skeletal muscle contraction (GO:0014728) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of twitch skeletal muscle contraction (GO:0014724) 2 0 .20 - < 0.01 1.00E00 1.00E00 twitch skeletal muscle contraction (GO:0014721) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of antimicrobial humoral response (GO:0002759) 6 0 .59 - < 0.01 1.00E00 1.00E00 positive regulation of RNA polymerase II transcription preinitiation complex assembly (GO:0045899) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 negative regulation of anion channel activity (GO:0010360) 5 0 .49 - < 0.01 1.00E00 1.00E00 renal albumin absorption (GO:0097018) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of RNA polymerase II transcription preinitiation complex assembly (GO:0045898) 14 0 1.38 - < 0.01 6.30E-01 1.00E00 mitochondrial fusion (GO:0008053) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 sensory organ boundary specification (GO:0008052) 1 0 .10 - < 0.01 1.00E00 1.00E00 female courtship behavior (GO:0008050) 3 0 .30 - < 0.01 1.00E00 1.00E00 eukaryotic translation initiation factor 4F complex assembly (GO:0097010) 2 0 .20 - < 0.01 1.00E00 1.00E00 skeletal muscle satellite cell activation (GO:0014719) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of satellite cell activation involved in skeletal muscle regeneration (GO:0014718) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of satellite cell activation involved in skeletal muscle regeneration (GO:0014717) 2 0 .20 - < 0.01 1.00E00 1.00E00 antigen processing and presentation following phagocytosis (GO:0002747) 1 0 .10 - < 0.01 1.00E00 1.00E00 male courtship behavior (GO:0008049) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of synaptic assembly at neuromuscular junction (GO:0045886) 1 0 .10 - < 0.01 1.00E00 1.00E00 modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade (GO:0085032) 1 0 .10 - < 0.01 1.00E00 1.00E00 synaptic target recognition (GO:0008039) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of dendritic cell cytokine production (GO:0002731) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of sister chromatid cohesion (GO:0045876) 8 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of sister chromatid cohesion (GO:0045875) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of sequestering of zinc ion (GO:0061090) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045870) 2 0 .20 - < 0.01 1.00E00 1.00E00 protein K6-linked ubiquitination (GO:0085020) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of natural killer cell cytokine production (GO:0002729) 5 0 .49 - < 0.01 1.00E00 1.00E00 response to non-ionic osmotic stress (GO:0010335) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of sequestering of zinc ion (GO:0061088) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045869) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of protein refolding (GO:0061084) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of protein refolding (GO:0061083) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of prostaglandin secretion involved in immune response (GO:0061078) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of neural retina development (GO:0061074) 1 0 .10 - < 0.01 1.00E00 1.00E00 ciliary body morphogenesis (GO:0061073) 4 0 .40 - < 0.01 1.00E00 1.00E00 iris morphogenesis (GO:0061072) 6 0 .59 - < 0.01 1.00E00 1.00E00 protein localization to kinetochore involved in kinetochore assembly (GO:1903394) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of adherens junction organization (GO:1903393) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of adherens junction organization (GO:1903392) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of adherens junction organization (GO:1903391) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of membrane potential (GO:0045838) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 sclerotome development (GO:0061056) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of homophilic cell adhesion (GO:1903387) 1 0 .10 - < 0.01 1.00E00 1.00E00 myotome development (GO:0061055) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of homophilic cell adhesion (GO:1903385) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of meiotic nuclear division (GO:0045835) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway (GO:1903384) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway (GO:1903383) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway (GO:1903382) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway (GO:1903381) 1 0 .10 - < 0.01 1.00E00 1.00E00 nucleoside bisphosphate catabolic process (GO:0033869) 6 0 .59 - < 0.01 1.00E00 1.00E00 nucleoside bisphosphate biosynthetic process (GO:0033866) 30 0 2.97 - < 0.01 1.07E-01 8.97E-01 positive regulation of NAD(P)H oxidase activity (GO:0033864) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of NAD(P)H oxidase activity (GO:0033861) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of NAD(P)H oxidase activity (GO:0033860) 7 0 .69 - < 0.01 1.00E00 1.00E00 forebrain astrocyte development (GO:0021897) 2 0 .20 - < 0.01 1.00E00 1.00E00 forebrain astrocyte differentiation (GO:0021896) 2 0 .20 - < 0.01 1.00E00 1.00E00 cerebral cortex neuron differentiation (GO:0021895) 21 0 2.08 - < 0.01 2.52E-01 1.00E00 cerebral cortex GABAergic interneuron development (GO:0021894) 4 0 .40 - < 0.01 1.00E00 1.00E00 cerebral cortex GABAergic interneuron fate commitment (GO:0021893) 2 0 .20 - < 0.01 1.00E00 1.00E00 cerebral cortex GABAergic interneuron differentiation (GO:0021892) 7 0 .69 - < 0.01 1.00E00 1.00E00 olfactory bulb interneuron development (GO:0021891) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of branching involved in lung morphogenesis (GO:0061048) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of branching involved in lung morphogenesis (GO:0061047) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of isotype switching (GO:0045829) 5 0 .49 - < 0.01 1.00E00 1.00E00 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway (GO:1903378) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of branching involved in lung morphogenesis (GO:0061046) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway (GO:1903377) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of isoprenoid metabolic process (GO:0045828) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of isoprenoid metabolic process (GO:0045827) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway (GO:1903376) 9 0 .89 - < 0.01 1.00E00 1.00E00 negative regulation of vascular wound healing (GO:0061044) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of vascular wound healing (GO:0061043) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of endoplasmic reticulum tubular network organization (GO:1903373) 4 0 .40 - < 0.01 1.00E00 1.00E00 regulation of endoplasmic reticulum tubular network organization (GO:1903371) 6 0 .59 - < 0.01 1.00E00 1.00E00 female gonad morphogenesis (GO:0061040) 1 0 .10 - < 0.01 1.00E00 1.00E00 olfactory bulb interneuron differentiation (GO:0021889) 9 0 .89 - < 0.01 1.00E00 1.00E00 uterus morphogenesis (GO:0061038) 3 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of glycogen catabolic process (GO:0045819) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of glycogen catabolic process (GO:0045818) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of fear response (GO:1903367) 4 0 .40 - < 0.01 1.00E00 1.00E00 olfactory bulb mitral cell layer development (GO:0061034) 2 0 .20 - < 0.01 1.00E00 1.00E00 secretion by lung epithelial cell involved in lung growth (GO:0061033) 3 0 .30 - < 0.01 1.00E00 1.00E00 protein localization to basolateral plasma membrane (GO:1903361) 3 0 .30 - < 0.01 1.00E00 1.00E00 forebrain neuron fate commitment (GO:0021877) 6 0 .59 - < 0.01 1.00E00 1.00E00 Wnt signaling pathway involved in forebrain neuroblast division (GO:0021874) 2 0 .20 - < 0.01 1.00E00 1.00E00 Cajal-Retzius cell differentiation (GO:0021870) 1 0 .10 - < 0.01 1.00E00 1.00E00 arabinose metabolic process (GO:0019566) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of Golgi organization (GO:1903358) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 umbilical cord development (GO:0061027) 2 0 .20 - < 0.01 1.00E00 1.00E00 cardiac muscle tissue regeneration (GO:0061026) 1 0 .10 - < 0.01 1.00E00 1.00E00 glycerol catabolic process (GO:0019563) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of nucleus organization (GO:1903353) 2 0 .20 - < 0.01 1.00E00 1.00E00 L-ornithine transmembrane transport (GO:1903352) 7 0 .69 - < 0.01 1.00E00 1.00E00 histidine catabolic process to glutamate and formamide (GO:0019556) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of bicellular tight junction assembly (GO:1903348) 5 0 .49 - < 0.01 1.00E00 1.00E00 hepatoblast differentiation (GO:0061017) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of bicellular tight junction assembly (GO:1903347) 4 0 .40 - < 0.01 1.00E00 1.00E00 snRNA import into nucleus (GO:0061015) 2 0 .20 - < 0.01 1.00E00 1.00E00 glutamate catabolic process to 2-oxoglutarate (GO:0019551) 2 0 .20 - < 0.01 1.00E00 1.00E00 glutamate catabolic process to aspartate (GO:0019550) 2 0 .20 - < 0.01 1.00E00 1.00E00 hepatic duct development (GO:0061011) 1 0 .10 - < 0.01 1.00E00 1.00E00 excretion (GO:0007588) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 gall bladder development (GO:0061010) 2 0 .20 - < 0.01 1.00E00 1.00E00 cerebral cortex GABAergic interneuron migration (GO:0021853) 2 0 .20 - < 0.01 1.00E00 1.00E00 pyramidal neuron migration (GO:0021852) 2 0 .20 - < 0.01 1.00E00 1.00E00 arginine catabolic process to ornithine (GO:0019547) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of vacuolar transport (GO:1903337) 1 0 .10 - < 0.01 1.00E00 1.00E00 arginine catabolic process to glutamate (GO:0019544) 1 0 .10 - < 0.01 1.00E00 1.00E00 propionate catabolic process (GO:0019543) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of vacuolar transport (GO:1903336) 1 0 .10 - < 0.01 1.00E00 1.00E00 pattern specification involved in kidney development (GO:0061004) 4 0 .40 - < 0.01 1.00E00 1.00E00 propionate biosynthetic process (GO:0019542) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of vacuolar transport (GO:1903335) 2 0 .20 - < 0.01 1.00E00 1.00E00 propionate metabolic process (GO:0019541) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of protein folding (GO:1903334) 7 0 .69 - < 0.01 1.00E00 1.00E00 negative regulation of protein folding (GO:1903333) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of dendritic spine morphogenesis (GO:0061002) 6 0 .59 - < 0.01 1.00E00 1.00E00 negative regulation of dendritic spine development (GO:0061000) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 positive regulation of iron-sulfur cluster assembly (GO:1903331) 1 0 .10 - < 0.01 1.00E00 1.00E00 nucleolar fragmentation (GO:0007576) 1 0 .10 - < 0.01 1.00E00 1.00E00 neuroblast division in subventricular zone (GO:0021849) 3 0 .30 - < 0.01 1.00E00 1.00E00 substrate-independent telencephalic tangential interneuron migration (GO:0021843) 5 0 .49 - < 0.01 1.00E00 1.00E00 chemorepulsion involved in interneuron migration from the subpallium to the cortex (GO:0021842) 1 0 .10 - < 0.01 1.00E00 1.00E00 directional guidance of interneurons involved in migration from the subpallium to the cortex (GO:0021840) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of iron-sulfur cluster assembly (GO:1903329) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of tRNA metabolic process (GO:1903327) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of tRNA metabolic process (GO:1903326) 2 0 .20 - < 0.01 1.00E00 1.00E00 oxalate transport (GO:0019532) 5 0 .49 - < 0.01 1.00E00 1.00E00 oxygen metabolic process (GO:0072592) 2 0 .20 - < 0.01 1.00E00 1.00E00 taurine metabolic process (GO:0019530) 7 0 .69 - < 0.01 1.00E00 1.00E00 motogenic signaling involved in postnatal olfactory bulb interneuron migration (GO:0021837) 1 0 .10 - < 0.01 1.00E00 1.00E00 chemorepulsion involved in postnatal olfactory bulb interneuron migration (GO:0021836) 2 0 .20 - < 0.01 1.00E00 1.00E00 embryonic olfactory bulb interneuron precursor migration (GO:0021831) 2 0 .20 - < 0.01 1.00E00 1.00E00 interneuron migration from the subpallium to the cortex (GO:0021830) 4 0 .40 - < 0.01 1.00E00 1.00E00 caveolin-mediated endocytosis (GO:0072584) 4 0 .40 - < 0.01 1.00E00 1.00E00 D-gluconate metabolic process (GO:0019521) 2 0 .20 - < 0.01 1.00E00 1.00E00 aldonic acid metabolic process (GO:0019520) 2 0 .20 - < 0.01 1.00E00 1.00E00 tricuspid valve formation (GO:0003195) 3 0 .30 - < 0.01 1.00E00 1.00E00 postnatal olfactory bulb interneuron migration (GO:0021827) 3 0 .30 - < 0.01 1.00E00 1.00E00 substrate-independent telencephalic tangential migration (GO:0021826) 5 0 .49 - < 0.01 1.00E00 1.00E00 substrate-dependent cerebral cortex tangential migration (GO:0021825) 3 0 .30 - < 0.01 1.00E00 1.00E00 cerebral cortex tangential migration using cell-cell interactions (GO:0021823) 3 0 .30 - < 0.01 1.00E00 1.00E00 glycine receptor clustering (GO:0072579) 1 0 .10 - < 0.01 1.00E00 1.00E00 endothelial cell apoptotic process (GO:0072577) 3 0 .30 - < 0.01 1.00E00 1.00E00 lactate oxidation (GO:0019516) 1 0 .10 - < 0.01 1.00E00 1.00E00 histone H3-K4 trimethylation (GO:0080182) 17 0 1.68 - < 0.01 3.94E-01 1.00E00 tolerance induction to lipopolysaccharide (GO:0072573) 2 0 .20 - < 0.01 1.00E00 1.00E00 S-adenosylhomocysteine catabolic process (GO:0019510) 1 0 .10 - < 0.01 1.00E00 1.00E00 dosage compensation (GO:0007549) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 regulation of pyruvate kinase activity (GO:1903302) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of hexokinase activity (GO:1903300) 2 0 .20 - < 0.01 1.00E00 1.00E00 primary sex determination, germ-line (GO:0007542) 2 0 .20 - < 0.01 1.00E00 1.00E00 tricuspid valve morphogenesis (GO:0003186) 6 0 .59 - < 0.01 1.00E00 1.00E00 sinoatrial valve morphogenesis (GO:0003185) 1 0 .10 - < 0.01 1.00E00 1.00E00 extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration (GO:0021816) 1 0 .10 - < 0.01 1.00E00 1.00E00 L-methionine salvage from methylthioadenosine (GO:0019509) 5 0 .49 - < 0.01 1.00E00 1.00E00 neuronal-glial interaction involved in cerebral cortex radial glia guided migration (GO:0021812) 1 0 .10 - < 0.01 1.00E00 1.00E00 hydrogen peroxide transmembrane transport (GO:0080170) 1 0 .10 - < 0.01 1.00E00 1.00E00 type B pancreatic cell maturation (GO:0072560) 1 0 .10 - < 0.01 1.00E00 1.00E00 lateral sprouting involved in mammary gland duct morphogenesis (GO:0060599) 1 0 .10 - < 0.01 1.00E00 1.00E00 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis (GO:0060598) 1 0 .10 - < 0.01 1.00E00 1.00E00 primary sex determination (GO:0007538) 2 0 .20 - < 0.01 1.00E00 1.00E00 mammary placode formation (GO:0060596) 2 0 .20 - < 0.01 1.00E00 1.00E00 chondroblast differentiation (GO:0060591) 2 0 .20 - < 0.01 1.00E00 1.00E00 tricuspid valve development (GO:0003175) 6 0 .59 - < 0.01 1.00E00 1.00E00 cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration (GO:0021808) 1 0 .10 - < 0.01 1.00E00 1.00E00 sinoatrial valve development (GO:0003172) 1 0 .10 - < 0.01 1.00E00 1.00E00 initiation of movement involved in cerebral cortex radial glia guided migration (GO:0021806) 1 0 .10 - < 0.01 1.00E00 1.00E00 blood vessel lumenization (GO:0072554) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of protein serine/threonine phosphatase activity (GO:0080163) 2 0 .20 - < 0.01 1.00E00 1.00E00 terminal button organization (GO:0072553) 3 0 .30 - < 0.01 1.00E00 1.00E00 establishment of synaptic specificity at neuromuscular junction (GO:0007529) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of lipoprotein lipid oxidation (GO:0060588) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of lipoprotein lipid oxidation (GO:0060587) 1 0 .10 - < 0.01 1.00E00 1.00E00 adult somatic muscle development (GO:0007527) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of prostaglandin-endoperoxide synthase activity (GO:0060585) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of prostaglandin-endoperoxide synthase activity (GO:0060584) 3 0 .30 - < 0.01 1.00E00 1.00E00 muscle cell fate determination (GO:0007521) 2 0 .20 - < 0.01 1.00E00 1.00E00 atrioventricular bundle cell differentiation (GO:0003167) 1 0 .10 - < 0.01 1.00E00 1.00E00 Purkinje myocyte development (GO:0003165) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of fertilization (GO:0080154) 9 0 .89 - < 0.01 1.00E00 1.00E00 superior vena cava morphogenesis (GO:0060578) 1 0 .10 - < 0.01 1.00E00 1.00E00 pulmonary vein morphogenesis (GO:0060577) 1 0 .10 - < 0.01 1.00E00 1.00E00 intestinal epithelial cell maturation (GO:0060574) 2 0 .20 - < 0.01 1.00E00 1.00E00 morphogenesis of an endothelium (GO:0003159) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 regulation of animal organ formation (GO:0003156) 20 0 1.98 - < 0.01 2.51E-01 1.00E00 muscular septum morphogenesis (GO:0003150) 5 0 .49 - < 0.01 1.00E00 1.00E00 glycolate biosynthetic process (GO:0046295) 1 0 .10 - < 0.01 1.00E00 1.00E00 formaldehyde catabolic process (GO:0046294) 2 0 .20 - < 0.01 1.00E00 1.00E00 fibroblast activation (GO:0072537) 4 0 .40 - < 0.01 1.00E00 1.00E00 formaldehyde biosynthetic process (GO:0046293) 1 0 .10 - < 0.01 1.00E00 1.00E00 formaldehyde metabolic process (GO:0046292) 4 0 .40 - < 0.01 1.00E00 1.00E00 amino acid homeostasis (GO:0080144) 5 0 .49 - < 0.01 1.00E00 1.00E00 mesoderm migration involved in gastrulation (GO:0007509) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of DNA-templated transcription, termination (GO:0060567) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of postsynaptic density protein 95 clustering (GO:1902897) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of DNA-templated transcription, termination (GO:0060566) 1 0 .10 - < 0.01 1.00E00 1.00E00 terminal web assembly (GO:1902896) 3 0 .30 - < 0.01 1.00E00 1.00E00 mesodermal cell fate determination (GO:0007500) 1 0 .10 - < 0.01 1.00E00 1.00E00 determination of left/right asymmetry in lateral mesoderm (GO:0003140) 4 0 .40 - < 0.01 1.00E00 1.00E00 pyrimidine-containing compound catabolic process (GO:0072529) 18 0 1.78 - < 0.01 4.00E-01 1.00E00 pyrimidine-containing compound biosynthetic process (GO:0072528) 22 0 2.18 - < 0.01 2.56E-01 1.00E00 protein localization to spindle microtubule (GO:1902889) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of vitamin D biosynthetic process (GO:0060557) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of response to oxidative stress (GO:1902884) 7 0 .69 - < 0.01 1.00E00 1.00E00 positive regulation of fructose 1,6-bisphosphate metabolic process (GO:0060552) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of fructose 1,6-bisphosphate metabolic process (GO:0060551) 1 0 .10 - < 0.01 1.00E00 1.00E00 secondary heart field specification (GO:0003139) 8 0 .79 - < 0.01 1.00E00 1.00E00 positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity (GO:0060550) 1 0 .10 - < 0.01 1.00E00 1.00E00 primary heart field specification (GO:0003138) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of heart induction by canonical Wnt signaling pathway (GO:0003136) 1 0 .10 - < 0.01 1.00E00 1.00E00 endodermal-mesodermal cell signaling involved in heart induction (GO:0003134) 3 0 .30 - < 0.01 1.00E00 1.00E00 endodermal-mesodermal cell signaling (GO:0003133) 3 0 .30 - < 0.01 1.00E00 1.00E00 BMP signaling pathway involved in heart induction (GO:0003130) 3 0 .30 - < 0.01 1.00E00 1.00E00 proteasome core complex assembly (GO:0080129) 1 0 .10 - < 0.01 1.00E00 1.00E00 stilbene catabolic process (GO:0046272) 1 0 .10 - < 0.01 1.00E00 1.00E00 CAAX-box protein maturation (GO:0080120) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of fructose 1,6-bisphosphate 1-phosphatase activity (GO:0060549) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of necroptotic process (GO:0060546) 15 0 1.48 - < 0.01 3.90E-01 1.00E00 positive regulation of necroptotic process (GO:0060545) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of necroptotic process (GO:0060544) 19 0 1.88 - < 0.01 4.08E-01 1.00E00 regulation of strand invasion (GO:0060542) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of amacrine cell differentiation (GO:1902871) 2 0 .20 - < 0.01 1.00E00 1.00E00 heart induction (GO:0003129) 3 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of amacrine cell differentiation (GO:1902870) 1 0 .10 - < 0.01 1.00E00 1.00E00 heart field specification (GO:0003128) 9 0 .89 - < 0.01 1.00E00 1.00E00 DNA demethylation (GO:0080111) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 regulation of amacrine cell differentiation (GO:1902869) 3 0 .30 - < 0.01 1.00E00 1.00E00 cartilage morphogenesis (GO:0060536) 7 0 .69 - < 0.01 1.00E00 1.00E00 regulation of retina development in camera-type eye (GO:1902866) 1 0 .10 - < 0.01 1.00E00 1.00E00 trachea cartilage morphogenesis (GO:0060535) 2 0 .20 - < 0.01 1.00E00 1.00E00 trachea cartilage development (GO:0060534) 6 0 .59 - < 0.01 1.00E00 1.00E00 bronchus cartilage development (GO:0060532) 2 0 .20 - < 0.01 1.00E00 1.00E00 propionyl-CoA biosynthetic process (GO:1902860) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of vasoconstriction by circulating norepinephrine (GO:0003117) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of vasoconstriction by norepinephrine (GO:0003116) 1 0 .10 - < 0.01 1.00E00 1.00E00 propionyl-CoA catabolic process (GO:1902859) 1 0 .10 - < 0.01 1.00E00 1.00E00 propionyl-CoA metabolic process (GO:1902858) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of non-motile cilium assembly (GO:1902857) 13 0 1.29 - < 0.01 6.23E-01 1.00E00 negative regulation of non-motile cilium assembly (GO:1902856) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of non-motile cilium assembly (GO:1902855) 16 0 1.58 - < 0.01 3.90E-01 1.00E00 activation of prostate induction by androgen receptor signaling pathway (GO:0060520) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of the force of heart contraction by chemical signal (GO:0003108) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of glomerular filtration by angiotensin (GO:0003106) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of glomerular filtration (GO:0003105) 3 0 .30 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by endothelin (GO:0003100) 5 0 .49 - < 0.01 1.00E00 1.00E00 terpene catabolic process (GO:0046247) 2 0 .20 - < 0.01 1.00E00 1.00E00 kynurenic acid biosynthetic process (GO:0034276) 1 0 .10 - < 0.01 1.00E00 1.00E00 kynurenic acid metabolic process (GO:0034275) 1 0 .10 - < 0.01 1.00E00 1.00E00 epithelial cell proliferation involved in prostatic bud elongation (GO:0060517) 1 0 .10 - < 0.01 1.00E00 1.00E00 primary prostatic bud elongation (GO:0060516) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic spindle elongation (GO:1902846) 1 0 .10 - < 0.01 1.00E00 1.00E00 prostatic bud formation (GO:0060513) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of autophagy in response to ER overload (GO:0034263) 3 0 .30 - < 0.01 1.00E00 1.00E00 smoothened signaling pathway involved in lung development (GO:0060506) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of proline import across plasma membrane (GO:1902836) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of proline import across plasma membrane (GO:1902834) 1 0 .10 - < 0.01 1.00E00 1.00E00 bud dilation involved in lung branching (GO:0060503) 1 0 .10 - < 0.01 1.00E00 1.00E00 epithelial cell proliferation involved in lung morphogenesis (GO:0060502) 3 0 .30 - < 0.01 1.00E00 1.00E00 aflatoxin catabolic process (GO:0046223) 2 0 .20 - < 0.01 1.00E00 1.00E00 aflatoxin metabolic process (GO:0046222) 2 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of late endosome to lysosome transport (GO:1902824) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of late endosome to lysosome transport (GO:1902823) 1 0 .10 - < 0.01 1.00E00 1.00E00 regulation of late endosome to lysosome transport (GO:1902822) 2 0 .20 - < 0.01 1.00E00 1.00E00 nitric oxide catabolic process (GO:0046210) 1 0 .10 - < 0.01 1.00E00 1.00E00 snoRNA splicing (GO:0034247) 2 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) 12 0 1.19 - < 0.01 6.17E-01 1.00E00 regulation of transcription elongation from RNA polymerase II promoter (GO:0034243) 33 0 3.26 - < 0.01 6.95E-02 7.21E-01 negative regulation of protein localization to microtubule (GO:1902817) 5 0 .49 - < 0.01 1.00E00 1.00E00 regulation of protein localization to microtubule (GO:1902816) 5 0 .49 - < 0.01 1.00E00 1.00E00 negative regulation of macrophage fusion (GO:0034240) 1 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of skeletal muscle fiber differentiation (GO:1902811) 3 0 .30 - < 0.01 1.00E00 1.00E00 nor-spermidine metabolic process (GO:0046204) 1 0 .10 - < 0.01 1.00E00 1.00E00 spermidine catabolic process (GO:0046203) 2 0 .20 - < 0.01 1.00E00 1.00E00 macrophage fusion (GO:0034238) 2 0 .20 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle fiber differentiation (GO:1902809) 4 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic vesicle transport (GO:1902805) 2 0 .20 - < 0.01 1.00E00 1.00E00 enkephalin processing (GO:0034230) 1 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of synaptic vesicle transport (GO:1902804) 1 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to zinc ion starvation (GO:0034224) 1 0 .10 - < 0.01 1.00E00 1.00E00