"Table S7. Top over-represented GO groups in the list of genes adjacent to hypermethylated CpGs. Columns are: GO ID, name of the GO gene set, number of genes annotated to that gene set and associated to a hypermethylated CpG, Benjamini-Hochberg corrected enrichment p value (which the data is sorted by), Multifunctionality (MF) score and the names of genes annotated to that gene set and associated to a hypermethylated CpG.",,,,,
ID,Name,NumGenes,CorrectedPvalue,Multifunctionality,GeneMemberDiff
GO:0051056,regulation of small GTPase mediated signal transduction,321,1E-07,0.707,"ABL1, ABL2, ABR, AKAP13, ARAP1, ARAP3, ARFGAP1, ARHGAP10, ARHGAP12, ARHGAP18, ARHGAP20, ARHGAP25, ARHGAP26, ARHGAP29, ARHGAP32, ARHGAP39, ARHGAP44, ARHGAP8, ARHGDIA, ARHGEF10L, ARHGEF16, ARHGEF26, ARHGEF28, ARHGEF3, ARHGEF39, ARHGEF4, ARHGEF40, ARHGEF7, AUTS2, BCR, CGNL1, CUL3, CYTH1, DAB2IP, DENND1A, DLC1, DNMBP, EPHB2, EPS8L2, F2R, F2RL1, FARP1, FARP2, FGD3, FGD6, FLCN, GPR35, IQSEC1, ITGA3, KANK1, KANK2, KITLG, KRAS, LPAR1, MAPKAP1, MAPRE2, MCF2L2, MFN2, NET1, NGEF, NOTCH1, NRG1, PIK3R2, PLCE1, PLEKHG1, PLEKHG5, PREX1, PSD, PSD4, RAF1, RALBP1, RALGAPA1, RALGAPA2, RALGPS2, RAP1GAP, RAP1GAP2, RAPGEF1, RASA2, RASA3, RASGRP1, RHOBTB1, RHOBTB2, RHOF, RHOH, RHOT2, SH3BP1, SIPA1, SIPA1L1, SIPA1L2, SIPA1L3, SQSTM1, SRC, SRGAP1, SRGAP3, SSX2IP, SYNGAP1, TIAM1, TIMP2, TRIO, VAV1, VAV2"
GO:0043547,positive regulation of GTPase activity,369,4E-07,0.59,"ABR, ACAP2, ACAP3, ADAP1, AGAP1, AGRN, AKT2, ALDH1A1, ANKRD27, ARAP1, ARAP3, ARFGAP1, ARFGAP3, ARHGAP10, ARHGAP12, ARHGAP18, ARHGAP20, ARHGAP25, ARHGAP26, ARHGAP27, ARHGAP29, ARHGAP32, ARHGAP39, ARHGAP44, ARHGAP8, ARHGDIA, ARHGEF10L, ARHGEF16, ARHGEF7, ASAP2, BCAS3, BCR, CAV2, CCL19, CCL24, CORO1C, DAB2IP, DENND1A, DLC1, DOCK1, DOCK4, DOCK9, DVL2, EZH2, F2R, F2RL1, FLCN, GIT2, GNAQ, GNB5, GSK3B, ICAM1, IQSEC1, LLGL1, LLGL2, MAPRE2, MTSS1L, NEDD9, NET1, NPRL3, ODAM, PICALM, PREX1, RABEP2, RABGAP1, RABGAP1L, RALBP1, RALGAPA1, RALGAPA2, RANGAP1, RAP1A, RAP1GAP, RAP1GAP2, RAPGEF1, RAPGEF2, RASA1, RASA2, RASA3, RASGRP1, RCC2, RGS12, RGS3, RGS8, RGS9, RIC8B, RIN2, RIN3, RINL, SH3BP1, SIPA1, SIPA1L1, SIPA1L2, SIPA1L3, SRGAP1, SRGAP3, SYNGAP1, TBC1D1, TBC1D10B, TBC1D14, TBC1D16, TBC1D2, TBC1D22A, TBC1D24, TBC1D2B, TBC1D4, TBC1D5, TBC1D8, TBC1D9, TIAM1, TSC1, VAV1"
GO:0034330,cell junction organization,204,3E-07,0.913,"ACTG1, ACTN1, ACTN4, ANG, ARHGEF7, ARVCF, BCL2, BCR, CADM1, CCM2, CDH1, CDH13, CDH23, CDH3, CLDN9, CNTNAP1, COL17A1, CSK, CTNNA1, CXADR, DLC1, DLG5, F2R, F2RL1, FBLIM1, FLCN, FRMPD2, FSCN1, GJB2, GNPAT, GRHL2, HDAC7, ITGA2, ITGB4, JUP, KIFC3, LAMA3, LAMA5, LAMB3, MARVELD3, MYADM, NF2, NFASC, NLGN2, NUMB, PARD3, PARD6G, PDPK1, PEAK1, PLEC, PLEKHA7, PRKCA, PRKCI, PTPRK, PTPRO, PVR, RCC2, SDK2, SH3BP1, SMAD3, SMAD7, SORBS1, SRC, TGFB1, TLN1, UGT8, VMP1, WDR1"
GO:0072001,renal system development,264,7E-06,0.993,"ACAT1, ACE, ACTA2, AGT, ALDH1A2, ANGPT2, AQP11, AQP2, ARG2, ARID5B, ARL3, BCL2, BMP2, BMP6, BMP7, CDKN1C, COL4A1, DACT2, DLG5, DLL1, EFNB2, ENPEP, EPCAM, EPHA4, FGF1, FGF2, FGFR1, FGFR2, FRAS1, GLI2, GLIS2, HNF1A, HOXD11, HPGD, ID3, IRX1, ITGA3, ITGB4, JAG1, KANK2, KLHL3, LAMA5, LGR4, LGR5, LRP4, MTSS1, MYO1E, NFIA, NIPBL, NOTCH1, NUP93, OSR2, OVOL1, PBX1, PCSK9, PDGFB, PGF, PKD1, PLCE1, PROM1, PROX1, PTCH1, PTPRO, RARA, RBP4, REN, SDC1, SMAD2, SMAD3, SMAD4, SMAD6, SMAD7, SOX8, STRA6, SULF2, TFAP2B, TP73, TRAF3IP1, TSC1, VEGFA, WNK4, WWTR1"
GO:0032869,cellular response to insulin stimulus,159,6E-06,0.969,"AKT2, ATP6V0D1, ATP6V0E1, ATP6V1A, ATP6V1C2, BAIAP2, BCAR1, CAV2, CDK4, CEACAM1, CFLAR, CSRP3, EEF2K, EIF4EBP1, FER, FOXO1, FOXO3, FOXO6, GHRHR, GRB14, GRB7, GSK3B, HDAC9, IGF1R, IGFBP1, INSR, LPIN1, LPIN2, LPIN3, MYO5A, PAK1, PARP1, PCSK9, PDK2, PDK4, PDPK1, PIK3CA, PIK3R1, PIK3R2, PIK3R3, PKLR, PPARG, PRKCI, PRKCZ, PTPN1, PTPRA, RAB10, SLC25A33, SOGA1, SORBS1, SRC, SREBF1, SRSF5, STAR, TBC1D4, TCIRG1, VAMP2, ZNF106"
GO:0001655,urogenital system development,298,1E-05,0.993,"ACAT1, ACE, ACTA2, AGT, ALDH1A2, ANGPT2, AQP11, AQP2, ARG2, ARID5B, ARL3, BCL2, BMP2, BMP6, BMP7, CDKN1C, COL4A1, DACT2, DLG5, DLL1, EFNB2, ENPEP, EPCAM, EPHA4, EPHB2, EPHB3, FGF1, FGF2, FGFR1, FGFR2, FRAS1, FRS2, GLI2, GLIS2, HNF1A, HOXD11, HPGD, ID3, IRX1, ITGA3, ITGB4, JAG1, KANK2, KLHL3, LAMA5, LGR4, LGR5, LRP4, MTSS1, MYO1E, NFIA, NIPBL, NOTCH1, NUP93, OSR2, OVOL1, PBX1, PCSK9, PDGFB, PGF, PKD1, PLCE1, PROM1, PROX1, PSAP, PTCH1, PTPRO, RARA, RBP4, REN, RXRA, SDC1, SMAD2, SMAD3, SMAD4, SMAD6, SMAD7, SOX8, STRA6, SULF2, TFAP2B, TP63, TP73, TRAF3IP1, TSC1, VEGFA, WDR77, WNK4, WWTR1"
GO:0071375,cellular response to peptide hormone stimulus,256,2E-05,0.979,"ADCY3, ADCY9, AGT, AKT2, ARID1B, ATP6V0D1, ATP6V0E1, ATP6V1A, ATP6V1C2, BAIAP2, BCAR1, BRIP1, CAV2, CDC6, CDK4, CEACAM1, CFLAR, CPS1, CSK, CSRP3, EEF2K, EIF4EBP1, FER, FOXO1, FOXO3, FOXO6, FYN, GHRHR, GJB2, GRB14, GRB7, GSK3B, HDAC9, HSF1, IGF1R, IGFBP1, INSR, LPIN1, LPIN2, LPIN3, MAX, MYO5A, NFE2L2, PAK1, PARP1, PCSK9, PDK2, PDK4, PDPK1, PIK3CA, PIK3R1, PIK3R2, PIK3R3, PKLR, POR, PPARG, PRKAR1B, PRKCD, PRKCI, PRKCZ, PRLR, PTK2, PTPN1, PTPRA, PXN, RAB10, RANGAP1, SLC25A33, SOGA1, SORBS1, SRC, SREBF1, SRSF5, STAR, STAT5A, STAT5B, TBC1D4, TCIRG1, VAMP2, ZNF106"
GO:0007156,homophilic cell adhesion via plasma membrane adhesion molecules,158,2E-05,0.00103,"CADM1, CDH1, CDH13, CDH22, CDH23, CDH3, CDHR1, CDHR2, CDHR5, CEACAM1, IGSF21, MPZL2, PCDH7, PCDHA1, PCDHA10, PCDHA11, PCDHA12, PCDHA13, PCDHA2, PCDHA3, PCDHA4, PCDHA5, PCDHA6, PCDHA7, PCDHA8, PCDHA9, PCDHAC1, PCDHAC2, PCDHGA1, PCDHGA10, PCDHGA11, PCDHGA12, PCDHGA2, PCDHGA3, PCDHGA4, PCDHGA5, PCDHGA6, PCDHGA7, PCDHGA8, PCDHGA9, PCDHGB1, PCDHGB2, PCDHGB3, PCDHGB4, PCDHGB6, PCDHGB7, PCDHGC3, PCDHGC4, PCDHGC5, PIK3CB, PKD1, PLXNB2, PVR, SDK2"
GO:0032868,response to insulin,221,3E-05,0.971,"AKT2, ATP6V0D1, ATP6V0E1, ATP6V1A, ATP6V1C2, BAIAP2, BCAR1, CAV2, CDK4, CEACAM1, CFLAR, CSRP3, EEF2K, EIF4EBP1, FABP3, FER, FOXO1, FOXO3, FOXO6, GHRHR, GRB14, GRB7, GSK3B, HDAC9, HSD11B2, ICAM1, IGF1R, IGFBP1, INPPL1, INSR, KBTBD2, LPIN1, LPIN2, LPIN3, MAX, MTOR, MYO5A, PAK1, PARP1, PCSK9, PDK2, PDK4, PDPK1, PIK3CA, PIK3R1, PIK3R2, PIK3R3, PKLR, PPARG, PRKCI, PRKCZ, PTPN1, PTPRA, RAB10, SCAP, SLC25A33, SOGA1, SORBS1, SORT1, SRC, SREBF1, SRSF5, STAR, TBC1D4, TCIRG1, TSC1, VAMP2, VGF, ZBTB7B, ZNF106"
GO:0001822,kidney development,251,3E-05,0.995,"ACAT1, ACE, ACTA2, AGT, ALDH1A2, ANGPT2, AQP11, AQP2, ARG2, ARID5B, ARL3, BCL2, BMP2, BMP6, BMP7, CDKN1C, DACT2, DLG5, DLL1, EFNB2, ENPEP, EPCAM, EPHA4, FGF1, FGF2, FGFR1, FGFR2, FRAS1, GLI2, GLIS2, HNF1A, HOXD11, HPGD, ID3, IRX1, ITGA3, JAG1, KANK2, KLHL3, LAMA5, LGR4, LRP4, MTSS1, MYO1E, NIPBL, NOTCH1, OSR2, OVOL1, PBX1, PCSK9, PDGFB, PGF, PKD1, PLCE1, PROM1, PROX1, PTCH1, PTPRO, RARA, REN, SDC1, SMAD2, SMAD3, SMAD4, SMAD6, SMAD7, SOX8, STRA6, SULF2, TFAP2B, TP73, TRAF3IP1, TSC1, VEGFA, WNK4, WWTR1"
GO:0098742,cell-cell adhesion via plasma-membrane adhesion molecules,248,4E-05,0.00775,"AMIGO3, ARVCF, ATP2C1, CADM1, CD6, CDH1, CDH13, CDH22, CDH23, CDH3, CDHR1, CDHR2, CDHR5, CEACAM1, CLDN10, CLDN11, CLDN7, CLDN9, CXADR, EPCAM, FGFRL1, GATA5, ICAM1, IGSF21, ITGAL, LRRC4, MAG, MPZL2, PCDH7, PCDHA1, PCDHA10, PCDHA11, PCDHA12, PCDHA13, PCDHA2, PCDHA3, PCDHA4, PCDHA5, PCDHA6, PCDHA7, PCDHA8, PCDHA9, PCDHAC1, PCDHAC2, PCDHGA1, PCDHGA10, PCDHGA11, PCDHGA12, PCDHGA2, PCDHGA3, PCDHGA4, PCDHGA5, PCDHGA6, PCDHGA7, PCDHGA8, PCDHGA9, PCDHGB1, PCDHGB2, PCDHGB3, PCDHGB4, PCDHGB6, PCDHGB7, PCDHGC3, PCDHGC4, PCDHGC5, PIK3CB, PKD1, PLXNB2, PTPRD, PTPRF, PVR, SDK2, TENM2, UNC5D"
GO:0046578,regulation of Ras protein signal transduction,225,6E-05,0.79,"ABL1, ABL2, ABR, AKAP13, ARFGAP1, ARHGAP44, ARHGDIA, ARHGEF10L, ARHGEF16, ARHGEF26, ARHGEF28, ARHGEF3, ARHGEF39, ARHGEF4, ARHGEF40, ARHGEF7, AUTS2, BCR, CUL3, CYTH1, DAB2IP, DENND1A, DLC1, DNMBP, EPHB2, EPS8L2, F2R, F2RL1, FARP1, FARP2, FGD3, FGD6, FLCN, GPR35, IQSEC1, ITGA3, KANK1, KANK2, KITLG, KRAS, LPAR1, MAPKAP1, MAPRE2, MCF2L2, MFN2, NET1, NGEF, NOTCH1, NRG1, PLCE1, PLEKHG1, PLEKHG5, PREX1, PSD, PSD4, RAF1, RALGPS2, RAPGEF1, RASA2, RASA3, RASGRP1, SQSTM1, SSX2IP, SYNGAP1, TIAM1, TIMP2, TRIO, VAV1, VAV2"
GO:0043405,regulation of MAP kinase activity,326,0.0002,0.964,"ADAM8, ADORA2B, AKAP13, BMP2, BMP7, CCL19, CSK, DAB2IP, DNAJA1, DTNBP1, DUSP10, DUSP16, DUSP2, DUSP8, DVL2, EDN3, EGFR, EPHA4, EPHB2, ERN2, ERP29, EZH2, F2R, FGF1, FGF2, FGFR1, FRS2, FZD5, GNG3, HIPK3, IGF1R, INSR, ITGA1, KITLG, KRAS, KSR1, LIME1, LPAR1, MAP2K1, MAP2K3, MAP2K5, MAP2K6, MAP3K14, MAP3K5, MAP3K7, MAP3K9, MAP4K2, MAP4K3, MAP4K5, MAPK1, MAPK14, MAPK3, MAPK8IP3, MAPKAPK3, MUC20, NOD1, NRG1, PAK1, PAQR3, PDCD4, PDE6G, PDGFA, PDGFB, PEA15, PIK3CB, PLCE1, PRDX2, PRKCD, PTPN1, PTPN6, RAF1, RAPGEF1, RASGRP1, RGS3, ROR2, S1PR2, SH2B3, SORL1, SPRED2, SRC, STK38, TAB2, TAOK3, TDGF1, TGFB1, THBS1, TIAM1, TP73, TRAF2, VEGFA"
GO:0030111,regulation of Wnt signaling pathway,349,0.0002,0.919,"ABL1, AES, ALPK2, ATP6V1C2, AXIN1, AXIN2, BICC1, BMP2, BTRC, CDH3, CMAHP, CSNK1D, CSNK1E, CSNK2A1, CUL3, CYLD, DAB2IP, DACT2, DVL2, EGFR, FAM53B, FGF9, FGFR2, FOLR1, FOXL1, FOXO1, GNAQ, GSK3B, HDAC1, HIC1, HMGXB4, IGFBP1, ITGA3, JADE1, JUP, KANK1, KREMEN1, LEF1, LGR4, LGR5, LGR6, LRP4, LYPD6, MAD2L2, MAPK14, MBD2, MDFI, MESP1, MLLT3, NFATC1, NKD1, NKD2, NLK, NOTCH1, NOTUM, NRARP, NXN, PPP1CA, PSMB10, PSMD11, PSMD3, PTK7, PTPRO, RAPGEF1, RECK, RNF220, ROR2, RUVBL1, SIAH2, SLC9A3R1, SMAD3, SRC, STK11, STK3, SULF2, TCF7L2, TIAM1, TLE3, TMEM88, TNFAIP3, TNKS, TRABD2B, TRPM4, TSKU, UBAC2, UBR5, USP34, WNK2, WNT10B, WNT5B, WWOX, WWTR1, YAP1, ZNRF3"
GO:0048732,gland development,396,0.0003,0.995,"AACS, ABL1, ACAT1, AK4, AKT2, ALDH1A2, ALDH1A3, ARID5B, ASXL1, BCL11B, BCL2, BMP2, BMP7, BMPR1A, BTRC, CCDC40, CDH1, CDKN1C, COBL, CPS1, CUL3, DDX39B, DNAAF1, E2F8, EDAR, EGFR, EPHB3, ESRP2, ETS1, EZH2, FGFR1, FGFR2, FPGS, FRS2, GHRHR, GLI2, HLX, HMOX1, HNF1A, HNF4A, HOXA3, HOXA5, IGF2R, INSR, ITGA2, JARID2, KRAS, LAMA5, LEF1, LRP5, LRP5L, MAN2A1, MAP2K1, MAPK1, MAPK3, MSX2, NCOA1, NEURL1, NOTCH1, NRG1, PAM, PAX6, PBX1, PCSK9, PDX1, PHF2, PIK3CA, PKD1, PLXNA1, POLB, PRDX2, PRLR, PROX1, PSAP, PTCH1, RAF1, RAP1A, RARA, RXRA, SEMA3A, SEMA3C, SLC29A1, SLC9A3R1, SMAD2, SMAD3, SMAD4, SP3, SRC, SRSF5, STAT5A, STAT5B, STRA6, SULF2, TDGF1, TFCP2L1, TGFB1, THRA, THRB, TP63, UPF2, USF2, VDR, VEGFA, WDR77, WNT2, ZBTB7B, ZDHHC21"
GO:0060541,respiratory system development,191,0.0005,0.994,"AGR2, ALDH1A2, ALDH1A3, ASXL1, BMPR1A, CCDC40, CHD7, CHI3L1, CRISPLD2, DLG5, DNAAF1, EGFR, EIF4EBP1, EP300, ESRP2, FBXW7, FGF1, FGF9, FGFR1, FGFR2, FGFRL1, FOXP2, GLI2, GRHL2, HOXA5, ITGA3, KCNAB1, KRAS, LAMA5, LEF1, LIPA, LTBP3, MAN2A1, MAP2K1, MAPK1, MAPK3, NOTCH1, PDGFA, PKD1, PLOD3, PPP1CA, PROX1, PTK7, RARA, RBP4, SLC23A1, SMAD2, SP3, SPDEF, SREBF1, STRA6, TBX4, THRA, THRB, TMEM38B, TNS3, TULP3, VEGFA, WNT2, YAP1"
GO:0051017,actin filament bundle assembly,62,0.0005,0.718,"ACTN1, ACTN4, ADD1, ADD2, ADD3, AIF1L, BAIAP2, BAIAP2L2, CUL3, DMTN, FAM107A, FAM171A1, FMN2, FSCN1, HSP90B1, ITGB5, LIMA1, MYO1B, NEDD9, RHOBTB1, RHOBTB2, RHOF, RND2, SORBS1, SPIRE1, SPIRE2, SRC"
GO:0002067,glandular epithelial cell differentiation,39,0.0005,0.873,"AGR2, BMP2, BMP6, CDK6, DLL1, FGFR2, HNF4A, HOXA5, NKX2-2, NOTCH1, PAX6, PDPK1, PDX1, PROX1, RARA, RFX3, RXRA, SPDEF, TP63, WDR77"
GO:0061564,axon development,393,0.0005,0.939,"ABL1, AFG3L2, AGRN, ANK3, APBB1, APBB2, ATL1, AUTS2, BAIAP2, BCL11B, BCL2, BMP7, BRSK1, CASP3, CCK, COBL, CTNNA1, DRGX, EFNA3, EFNA4, EFNB2, ENAH, EPHA10, EPHA4, EPHA8, EPHB2, EPHB3, EVL, EXT1, FAM129B, FEZ2, FGFR2, FOLR1, FRS2, FYN, GAB2, GLI2, GPC1, GRB7, HOXA2, KIF5B, KLF7, LGR6, LLGL1, LYPLA2, MAG, MAP1A, MAPK1, MAPK3, MAPK8IP3, MARK2, MATN2, MTR, NFASC, NIN, NOTCH1, NRCAM, NREP, NRXN3, NUMB, PARD3, PAX6, PDLIM7, PICALM, PIK3CA, PIK3CB, PIK3R1, PITPNA, PLXNA1, PLXNA2, PLXNB2, PLXNC1, PRKCA, PTCH1, PTK2, PTPRA, PTPRO, RAB10, RAP1GAP, RNF165, RTN4, RTN4RL1, SEMA3A, SEMA3B, SEMA3C, SEMA3F, SEMA6A, SHC3, SIAH1, SLIT1, SMAD4, SPTAN1, SPTBN1, SPTBN2, SPTBN5, SRC, STK11, STXBP1, SZT2, TRIM32, TRIO, TSKU, UNC5D, VEGFA"
GO:0031346,positive regulation of cell projection organization,375,0.0005,0.944,"ABL2, AGRN, AGT, ANAPC2, ANKRD27, APBB1, ARAP1, ARHGDIA, ARHGEF7, AUTS2, AVIL, BAIAP2, BCAS3, BMP7, CAMK1D, CAMK2B, CBFA2T2, CCDC88A, CCL19, CDC42EP4, CDC42EP5, CFLAR, COBL, CORO1C, CPEB3, CPNE5, CRABP2, CROCC, CUX1, DAB2IP, DDX56, DLG5, DVL2, EEF2K, EP300, EPHA4, EPS8L2, EZH2, F2RL1, FBXO31, FBXO38, FES, FGFR1, FOXO6, FSCN1, FYN, HDAC4, HTT, ITGA2, ITGA3, KCTD17, LPAR1, LRP8, LTK, MAP2K1, MAP6, MAPK6, MARK2, MARK4, METRN, MTOR, NEDD4L, NEURL1, NFE2L2, NIN, OBSL1, OPA1, PAK1, PALM, PARP6, PLXNA1, PLXNA2, PLXNB2, PLXNC1, PPP1R9A, PRKCI, PROM2, PTK7, PTPRD, RAB21, RAP1A, RAPGEF1, RAPGEF2, RND2, RNF157, ROR2, RREB1, SEPT9, SF3A2, SHANK2, SMURF1, SRC, STK11, TENM2, TIAM1, TRAK1, VEGFA, WASL, WRAP73"
GO:0030323,respiratory tube development,168,0.0006,0.993,"AGR2, ALDH1A2, ASXL1, BMPR1A, CCDC40, CHI3L1, CRISPLD2, DLG5, DNAAF1, EGFR, EIF4EBP1, EP300, ESRP2, FBXW7, FGF1, FGF9, FGFR1, FGFR2, FOXP2, GLI2, GRHL2, HOXA5, ITGA3, KRAS, LAMA5, LIPA, LTBP3, MAN2A1, MAP2K1, MAPK1, MAPK3, NOTCH1, PDGFA, PKD1, PLOD3, PPP1CA, PROX1, PTK7, RBP4, SLC23A1, SMAD2, SP3, SPDEF, SREBF1, STRA6, TBX4, THRA, THRB, TMEM38B, TNS3, TULP3, VEGFA, WNT2, YAP1"
GO:0008593,regulation of Notch signaling pathway,100,0.0006,0.929,"AAK1, ADAM10, BMP2K, BMP7, CBFA2T2, CREBBP, DLL1, DTX1, EGFR, EP300, EPN2, FAM129B, FBXW7, GALNT11, GATA5, GDPD5, HEY1, JAG1, JAG2, LLGL1, LLGL2, MAML2, MAML3, MESP1, NEURL1, NOTCH1, NRARP, POFUT1, PRKCI, SLC35C1, TP63, TSPEAR, WWP2, ZBTB7A, ZMIZ1"
GO:0008286,insulin receptor signaling pathway,85,0.0006,0.937,"AKT2, ATP6V0D1, ATP6V0E1, ATP6V1A, ATP6V1C2, BAIAP2, BCAR1, CAV2, CSRP3, EIF4EBP1, FER, FOXO1, FOXO3, FOXO6, GRB14, GRB7, GSK3B, IGF1R, IGFBP1, INSR, PDK2, PDK4, PIK3CA, PIK3R1, PIK3R2, PIK3R3, PTPN1, PTPRA, SOGA1, SORBS1, SREBF1, TCIRG1, ZNF106"
GO:0030324,lung development,165,0.0006,0.994,"AGR2, ALDH1A2, ASXL1, BMPR1A, CCDC40, CHI3L1, CRISPLD2, DLG5, DNAAF1, EGFR, EIF4EBP1, EP300, ESRP2, FBXW7, FGF1, FGF9, FGFR1, FGFR2, FOXP2, GLI2, GRHL2, HOXA5, ITGA3, KRAS, LAMA5, LIPA, LTBP3, MAN2A1, MAP2K1, MAPK1, MAPK3, NOTCH1, PDGFA, PKD1, PLOD3, PPP1CA, PROX1, PTK7, RBP4, SLC23A1, SMAD2, SP3, SPDEF, SREBF1, STRA6, TBX4, THRA, THRB, TMEM38B, TNS3, VEGFA, WNT2, YAP1"
GO:0001701,in utero embryonic development,360,0.0006,0.925,"ACVR1B, ACVRL1, ADAM10, ADCY9, ADD1, ANKRD11, APBA2, ARNT, ATP11A, BIRC6, BMP2, BMP7, BMPR1A, C2CD3, CAPN2, CASP8, CCM2, CDKN1C, CELF4, CHD7, CHTOP, CMIP, CTR9, CUL3, CUL4A, E2F8, EGFL8, EGFR, ELL, EMG1, EPN1, FGFR1, FGFR2, FLCN, FUT8, FZD5, GCM1, GINS4, GLI2, GNA12, GRHL2, HEY1, HSD17B2, HSF1, JAG2, KEAP1, LEF1, MAN2A1, MAP2K1, MAPK1, MBD3, MBNL1, MDFI, MFN2, MYO1E, NCOA1, NMT1, NOTCH1, NXN, OVOL2, PDGFB, PEMT, PKD1, PLOD3, POLB, POLG2, PTCH1, PTH1R, RTF1, RTN4, RXRA, SETD2, SH3PXD2A, SIN3A, SLC25A20, SLC25A34, SLC35E2B, SMAD2, SMAD3, SMAD4, SMG9, SOX6, SOX8, SP3, SSR2, ST14, STK3, SUPT6H, TFEB, TIE1, UBR3, VASH2, VEGFA, WDR74, WNT2, ZMIZ1"
GO:0032147,activation of protein kinase activity,310,0.0006,0.95,"ABL1, ADCY3, ADCY9, ADORA2B, ANG, ATG13, AXIN1, BMP2, CAB39, CARD10, CCDC88A, CCL19, CHI3L1, DAB2IP, DGKQ, EGFR, ERN2, ERP29, F2R, FGF1, FGF2, FRS2, GNG3, GPRC5C, INSR, ITGA1, KSR1, LPAR1, MAP2K1, MAP2K3, MAP2K5, MAP2K6, MAP3K14, MAP3K5, MAP3K7, MAP3K9, MAP4K2, MAP4K3, MAP4K5, MAPK1, MAPK14, MAPK3, MAPK8IP3, MAPKAP1, MAPKAPK3, MARK2, MLST8, MTOR, MUC20, NOD1, NRG1, PAK1, PAK6, PDE6G, PDGFB, PDPK1, PEA15, PIK3CA, PIK3CB, PLCE1, PRDX2, PRKAR1B, PRKCD, PRKCZ, PRLR, PRR5, PTPN1, RAF1, RAPGEF1, RICTOR, RPLP1, RPTOR, S1PR2, SRC, STK10, STK11, STK3, TAB2, TAOK3, TDGF1, THBS1, TP73, TRAF2, VEGFA"
GO:0034332,adherens junction organization,82,0.0006,0.78,"ACTN1, ANG, ARHGEF7, BCL2, BCR, CADM1, CDH1, CDH13, CDH23, CDH3, CSK, CTNNA1, DLC1, DLG5, ITGA2, JUP, KIFC3, LAMA5, NUMB, PDPK1, PEAK1, PLEKHA7, PTPRK, PVR, RCC2, SMAD7, SORBS1, SRC"
GO:0031099,regeneration,149,0.0006,0.986,"ADAM15, ANGPT2, ATIC, BCL2, CDK4, CFLAR, CTNNA1, DYSF, EGFR, EYS, EZH2, F7, FOLR1, FPGS, GATA4, GSN, HMOX1, IGF2R, IGFBP1, LGR6, LPIN1, MAG, MAPK8IP3, MATN2, MTR, MUSTN1, NINJ1, NINJ2, NOTCH1, NREP, PAX7, PDX1, PGF, PPARG, PPP3CA, PTCH1, PTPRF, RAP1A, RTN4RL1, SGCA, SOX15, SRSF5, SULF2, TEC, UPF2, WNT10B, YAP1"
GO:0061572,actin filament bundle organization,64,0.0006,0.732,"ACTN1, ACTN4, ADD1, ADD2, ADD3, AIF1L, BAIAP2, BAIAP2L2, CUL3, DMTN, FAM107A, FAM171A1, FMN2, FSCN1, HSP90B1, ITGB5, LIMA1, MYO1B, NEDD9, RHOBTB1, RHOBTB2, RHOF, RND2, SORBS1, SPIRE1, SPIRE2, SRC"
GO:0043406,positive regulation of MAP kinase activity,249,0.0007,0.966,"ADAM8, ADORA2B, AKAP13, BMP2, CCL19, CSK, DAB2IP, DVL2, EDN3, EGFR, EPHA4, ERN2, ERP29, EZH2, F2R, FGF1, FGF2, FGFR1, FRS2, FZD5, GNG3, INSR, ITGA1, KITLG, KRAS, KSR1, LPAR1, MAP2K1, MAP2K3, MAP2K5, MAP2K6, MAP3K14, MAP3K5, MAP3K7, MAP3K9, MAP4K2, MAP4K3, MAP4K5, MAPK1, MAPK14, MAPK3, MAPK8IP3, MAPKAPK3, MUC20, NOD1, NRG1, PAK1, PDE6G, PDGFA, PDGFB, PEA15, PIK3CB, PLCE1, PRDX2, PTPN1, RAF1, RAPGEF1, RASGRP1, ROR2, S1PR2, SRC, TAB2, TAOK3, TDGF1, TGFB1, THBS1, TIAM1, TP73, TRAF2, VEGFA"
GO:0010769,regulation of cell morphogenesis involved in differentiation,291,0.0009,0.945,"ABL1, ACTN4, ADAM10, ANAPC2, ANKRD27, ARHGAP44, ARHGDIA, ARHGEF7, BAIAP2, BARHL2, BRSK1, CAMK2B, CFL1, CORO1C, CRABP2, CUX1, DMTN, DOCK1, EEF2K, EPHA4, EPHB2, EPHB3, FBXO31, GSK3B, HECW2, KANK1, KIF13B, LRP4, LRP8, LZTS3, MAG, MAP2K1, MAP6, MARK2, METRN, MYADM, NEDD4L, NEDD9, NGEF, NIN, NRCAM, NSMF, OBSL1, OLFM4, OPA1, PAK1, PARP6, PLXNA1, PLXNA2, PLXNB2, PLXNC1, PPP1R9A, PPP3CA, PREX1, PTK2, PTPRD, PTPRO, RAB21, RAPGEF2, RCC2, RND2, RREB1, RTN4, SEMA3A, SEMA3B, SEMA3C, SEMA3F, SEMA4B, SEMA4C, SEMA6A, SIN3A, SIPA1L1, STK11, SYNGAP1, TIAM1, TRAK1, TRIOBP, VEGFA, ZSWIM5, ZSWIM6"
GO:0033500,carbohydrate homeostasis,181,0.0009,0.981,"AACS, ADRA1B, APPL2, BACE2, BAD, CSMD1, CSRP3, FFAR1, FGFR4, FOXK1, FOXK2, FOXO1, FOXO3, FOXO6, GATA4, GHRHR, HECTD4, HNF1A, HNF4A, ICAM1, IGF1R, INSR, KLF7, LEPR, MCU, MLXIPL, OPA1, PAX6, PDK2, PDK4, PDX1, PIK3CA, PIK3R1, PIK3R2, POLG, PPARG, PPP3CA, PRCP, PTCH1, PTPRN2, RAF1, RAP1A, RBP4, RPH3AL, SIN3A, SLC29A1, STAR, STK11, SUCNR1, TCF7L2, TFAP2B, VGF, ZBTB20, ZNF236"
GO:0034329,cell junction assembly,160,0.0009,0.912,"ACTG1, ACTN1, ACTN4, ARHGEF7, ARVCF, BCL2, BCR, CDH1, CDH13, CDH23, CDH3, CNTNAP1, COL17A1, CTNNA1, DLC1, DLG5, FBLIM1, FLCN, FRMPD2, FSCN1, GJB2, GNPAT, GRHL2, HDAC7, ITGA2, ITGB4, JUP, LAMA3, LAMA5, LAMB3, MARVELD3, NFASC, PARD3, PARD6G, PDPK1, PEAK1, PLEC, PRKCA, PRKCI, PTPRK, PTPRO, RCC2, SH3BP1, SMAD7, SORBS1, TLN1, UGT8, VMP1, WDR1"
GO:0001101,response to acid chemical,333,0.0009,0.989,"AACS, ABCC2, ABL2, ACER2, AKR1C3, ALAD, ALDH1A2, AQP1, AQP2, ASXL1, BAD, BAIAP2, BCL11A, BMP6, CAPN2, CASP3, CCL19, CDK4, CFL1, COL16A1, COL18A1, COL4A1, CPEB3, CPEB4, CPS1, CPT1A, DNMT1, DNMT3A, EGFR, F7, FABP3, FFAR1, FGFR2, FGFR4, FOLR1, FOXO1, FYN, GJB2, GNB1, GNPAT, GSN, HLCS, HOXA2, HSD17B2, HSF1, ICAM1, ID3, IGF2R, ITGA2, KCNK4, LTK, MTHFR, MTOR, MYB, NCOA1, NEURL1, NSMF, OGG1, OPA1, PDGFB, PDK4, PDX1, PEMT, PPARG, PPP1R9B, PPP5C, PRKCE, PTAFR, PTCH1, PTK7, RARA, RBP4, RPTOR, RXRA, SESN1, SIPA1, SLC1A2, SRC, SREBF1, TESC, TIE1, UBR1, VEGFA, WNT10B, WNT2, WNT5B, XRCC5, YAP1, YES1"
GO:1901653,cellular response to peptide,324,0.0009,0.982,"ABCC1, ADCY3, ADCY9, AGT, AKT2, ARID1B, ATP6V0D1, ATP6V0E1, ATP6V1A, ATP6V1C2, BAIAP2, BCAR1, BRIP1, CAV2, CDC6, CDK4, CEACAM1, CFLAR, CPS1, CSK, CSRP3, EEF2K, EIF4EBP1, EPHA4, FER, FOXO1, FOXO3, FOXO6, FYN, GHRHR, GJB2, GRB14, GRB7, GSK3B, HDAC9, HSF1, ICAM1, IGF1R, IGFBP1, INSR, KLF11, LPIN1, LPIN2, LPIN3, MAX, MIR106B, MIR200A, MYO5A, NFE2L2, NOD1, PAK1, PARP1, PCSK9, PDK2, PDK4, PDPK1, PIK3CA, PIK3R1, PIK3R2, PIK3R3, PKLR, POR, PPARG, PPP1R9B, PRKAR1B, PRKCD, PRKCI, PRKCZ, PRLR, PTK2, PTPN1, PTPRA, PXN, RAB10, RANGAP1, SLC25A33, SOGA1, SORBS1, SRC, SREBF1, SRSF5, STAR, STAT5A, STAT5B, TBC1D4, TCIRG1, VAMP2, ZNF106"
GO:0072073,kidney epithelium development,117,0.001,1,"ACAT1, AQP11, ARG2, BCL2, BMP2, BMP7, DLL1, EFNB2, EPCAM, EPHA4, FGF1, FGF2, FGFR1, FGFR2, HOXD11, IRX1, JAG1, KANK2, KLHL3, LAMA5, LGR4, MTSS1, MYO1E, NOTCH1, PBX1, PGF, PKD1, PROM1, PTCH1, PTPRO, RARA, SDC1, SMAD2, SMAD3, SMAD4, SMAD6, SMAD7, SOX8, TFAP2B, WNK4"
GO:0071902,positive regulation of protein serine/threonine kinase activity,323,0.001,0.964,"ADAM8, ADORA2B, AKAP13, BMP2, CAB39, CALM1, CCL19, CCND2, CCND3, CCNYL1, CDC6, CSK, DAB2IP, DVL2, EDN3, EGFR, EPHA4, ERN2, ERP29, EZH2, F2R, FAM20A, FGF1, FGF2, FGFR1, FRS2, FZD5, GNG3, INSR, ITGA1, KITLG, KRAS, KSR1, LPAR1, MAP2K1, MAP2K3, MAP2K5, MAP2K6, MAP3K14, MAP3K5, MAP3K7, MAP3K9, MAP4K2, MAP4K3, MAP4K5, MAPK1, MAPK14, MAPK3, MAPK8IP3, MAPKAPK3, MIR26B, MLST8, MUC20, NOD1, NRG1, PAK1, PARP6, PDE6G, PDGFA, PDGFB, PEA15, PIK3CB, PKD1, PLCE1, PRDX2, PROX1, PTPN1, RAF1, RAPGEF1, RAPGEF2, RASGRP1, ROR2, RPTOR, S1PR2, SRC, STK3, TAB2, TAOK3, TDGF1, TGFB1, THBS1, TIAM1, TP73, TRAF2, VEGFA"
GO:0042593,glucose homeostasis,180,0.001,0.981,"AACS, ADRA1B, APPL2, BACE2, BAD, CSMD1, CSRP3, FFAR1, FGFR4, FOXK1, FOXK2, FOXO1, FOXO3, FOXO6, GATA4, GHRHR, HECTD4, HNF1A, HNF4A, ICAM1, IGF1R, INSR, KLF7, LEPR, MCU, MLXIPL, OPA1, PAX6, PDK2, PDK4, PDX1, PIK3CA, PIK3R1, PIK3R2, POLG, PPARG, PPP3CA, PRCP, PTCH1, PTPRN2, RAF1, RAP1A, RBP4, RPH3AL, SIN3A, SLC29A1, STAR, STK11, SUCNR1, TCF7L2, TFAP2B, VGF, ZBTB20, ZNF236"
GO:0060562,epithelial tube morphogenesis,287,0.001,0.998,"ABL1, ACVRL1, ARID1A, ARL13B, BCL2, BMP2, BMP7, BTRC, C2CD3, CASP3, CCDC40, CCM2, CFL1, COBL, COL4A1, DLC1, DLG5, DLL1, DNAAF1, DVL2, EFNB2, EPHA4, ESRP2, FGF1, FGF2, FGFR2, FOLR1, GATA4, GLI2, GRHL2, HOXA5, HOXD11, IRX1, KDM2B, KLHL3, KRAS, LAMA5, LEF1, LGR4, LGR5, LRP5, LRP5L, MESP1, MSX2, MTHFD1, MTHFR, MTSS1, NOTCH1, NRARP, OVOL2, PAK1, PBX1, PGF, PKD1, PLXNB2, PPP1CA, PRKD2, PROX1, PTCH1, PTK7, RARA, SEMA4C, SETD2, SMAD3, SMAD4, SOX8, SRC, ST14, STK3, TBX20, TCAP, TGFB1, TRIM71, TSC1, TULP3, VDR, VEGFA, WNK4, YAP1"
GO:0045216,cell-cell junction organization,130,0.001,0.826,"ACTN4, ARVCF, CCM2, CDH1, CDH13, CDH23, CDH3, CLDN9, CNTNAP1, CTNNA1, CXADR, DLG5, F2R, F2RL1, FLCN, FRMPD2, FSCN1, GJB2, GNPAT, GRHL2, HDAC7, JUP, KIFC3, MARVELD3, MYADM, NF2, NFASC, NLGN2, PARD3, PARD6G, PLEKHA7, PRKCA, PRKCI, PTPRO, SDK2, SMAD3, TGFB1, TLN1, UGT8, WDR1"
GO:0007223,"Wnt signaling pathway, calcium modulating pathway",37,0.002,0.795,"AGO2, CALM1, FZD5, GNB1, LEF1, MAP3K7, NFATC1, NLK, PDE6A, PDE6B, PDE6G, PLCB2, PLCB3, PPP3CA, ROR2, TCF7L2, TNRC6B, TNRC6C"
GO:0007409,axonogenesis,360,0.002,0.937,"ABL1, AFG3L2, AGRN, ANK3, APBB1, APBB2, ATL1, AUTS2, BAIAP2, BCL11B, BCL2, BMP7, BRSK1, CCK, COBL, DRGX, EFNA3, EFNA4, EFNB2, ENAH, EPHA10, EPHA4, EPHA8, EPHB2, EPHB3, EVL, EXT1, FAM129B, FEZ2, FGFR2, FRS2, FYN, GAB2, GLI2, GPC1, GRB7, HOXA2, KIF5B, KLF7, LGR6, LLGL1, LYPLA2, MAP1A, MAPK1, MAPK3, MATN2, NFASC, NIN, NOTCH1, NRCAM, NRXN3, NUMB, PARD3, PAX6, PDLIM7, PICALM, PIK3CA, PIK3CB, PIK3R1, PITPNA, PLXNA1, PLXNA2, PLXNB2, PLXNC1, PRKCA, PTCH1, PTK2, PTPRA, PTPRO, RAB10, RAP1GAP, RNF165, SEMA3A, SEMA3B, SEMA3C, SEMA3F, SEMA6A, SHC3, SIAH1, SLIT1, SMAD4, SPTAN1, SPTBN1, SPTBN2, SPTBN5, SRC, STK11, STXBP1, SZT2, TRIO, TSKU, UNC5D, VEGFA"
GO:0031333,negative regulation of protein complex assembly,132,0.002,0.955,"ADD1, ADD2, ADD3, ANKRD27, AVIL, CAPG, CAPZB, CLDN7, CLU, DMTN, EIF4EBP1, EP300, GSK3B, GSN, INPP5J, KANK1, LCMT1, LDLRAD4, MYADM, PATL2, PEX14, PMEPA1, PRKCD, PRKCZ, RAF1, SIRT2, SMAD6, SORL1, SPTAN1, SPTBN1, SPTBN2, SPTBN5, SRC, STXBP1, TBX20, TFIP11, THRA, TMC8, TRAF3IP1, TRIM9, TRIOBP, VILL"
GO:0002064,epithelial cell development,183,0.002,0.96,"ACTA2, ARHGEF26, ARID4B, BCL11B, BFSP1, BMP6, CCM2, CDK6, COL18A1, DACT2, DLL1, DNASE1L2, E2F4, F2RL1, FGFR1, FLNB, FRS2, GRHL2, HNF4A, HOXA5, ICAM1, JAG1, LRTOMT, MYADM, MYO1E, MYO7A, NKX2-2, NOTCH1, PAX6, PDE4D, PDGFB, PDPK1, PLOD3, PPP1R16B, PROX1, PSAP, RAB1B, RAP1A, RAPGEF1, RAPGEF2, RARA, RFX3, SDC1, SIPA1L3, SLC9A3R1, SOX8, SPDEF, ST14, TFCP2L1, TP63, TRIOBP, VEZF1, WNT5B"
GO:0001763,morphogenesis of a branching structure,162,0.002,0.999,"BCL2, BMP2, BMP7, BTRC, COL13A1, COL16A1, COL4A1, DLG5, ESRP2, FGF1, FGF2, FGFR1, FGFR2, FRS2, FZD5, GCM1, GLI2, GRHL2, HOXA5, HOXD11, KRAS, LAMA5, LEF1, LRP5, LRP5L, MSX2, NOTCH1, NRARP, PAK1, PBX1, PGF, PKD1, PLXNA1, PPP1CA, PROX1, PTCH1, RERE, SEMA3A, SEMA3C, SETD2, SMAD4, SOX8, SRC, ST14, TBX20, TDGF1, TP63, VDR, VEGFA, YAP1"
GO:0051098,regulation of binding,366,0.002,0.986,"ABL1, ACE, ADAM15, ADD1, ADD2, ADRB3, AES, ANXA2, ARHGEF7, BCL2, BCL3, BMP2, C6orf106, CARD16, CSNK1E, CTBP2, CYLD, DAB2IP, DOT1L, DTNBP1, EBF2, EIF3E, EIF4A3, EP300, EPHA4, FAM129B, FBXW7, FKBP1A, GSK3B, HDAC4, HEY1, HIPK2, HMBOX1, HMOX1, HOXA3, HSF1, ID3, ITGA2, LEF1, MAD2L2, MAP2K1, MAPK3, MARK2, MBD2, MDFI, MED25, MSX2, NIPBL, NMD3, NRG1, NSD1, P2RY1, PARP1, PAX6, PAX7, PCBD1, PCSK9, PDGFB, PDX1, PER2, PEX14, PKD1, PLCL1, PLCL2, PPARG, PPP1CA, PPP3CA, PRKCD, PRMT8, PTPRF, RAPGEF2, RARA, SIN3A, SIRT2, SMAD2, SMAD3, SMAD4, SORL1, SPPL3, SRC, STK3, SUMO3, TCF7L2, TFAP4, TFIP11, TGFB1, TIAM1, TMC8, TNKS, TRAF2, UBASH3B, WFIKKN1, ZBTB7A, ZFPM1"
GO:1900006,positive regulation of dendrite development,73,0.002,0.84,"ANAPC2, ANKRD27, BAIAP2, BMP7, CAMK2B, COBL, CPEB3, CUX1, DAB2IP, DLG5, EEF2K, EPHA4, EZH2, FBXO31, FOXO6, LPAR1, LRP8, MAPK6, MTOR, NEURL1, OBSL1, OPA1, PARP6, PPP1R9A, PTPRD, RAB21, SHANK2, TIAM1"
GO:0048736,appendage development,167,0.002,0.939,"AFF3, ALDH1A2, BMP7, BMPR1A, C2CD3, CHD7, CRABP2, CREBBP, ECE1, FGF9, FGFR1, FGFR2, FRAS1, GLI2, GNA12, GRHL2, HDAC1, HOXD10, ITGB4, KREMEN1, LEF1, LRP4, MBNL1, MSX2, NIPBL, NOTCH1, OSR2, PAM, PBX1, PBX2, PLXNA2, PRRX1, PTCH1, RARA, RECK, RNF165, ROR2, RUNX2, SEMA3C, SMAD4, SMOC1, TBX4, TFAP2B, TP63, TRAF3IP1, TULP3, ZNF219, ZNRF3"
GO:0060173,limb development,167,0.002,0.939,"AFF3, ALDH1A2, BMP7, BMPR1A, C2CD3, CHD7, CRABP2, CREBBP, ECE1, FGF9, FGFR1, FGFR2, FRAS1, GLI2, GNA12, GRHL2, HDAC1, HOXD10, ITGB4, KREMEN1, LEF1, LRP4, MBNL1, MSX2, NIPBL, NOTCH1, OSR2, PAM, PBX1, PBX2, PLXNA2, PRRX1, PTCH1, RARA, RECK, RNF165, ROR2, RUNX2, SEMA3C, SMAD4, SMOC1, TBX4, TFAP2B, TP63, TRAF3IP1, TULP3, ZNF219, ZNRF3"
GO:0043434,response to peptide hormone,377,0.003,0.979,"ABCC2, ADCY3, ADCY9, AGT, AKT2, ARID1B, ATP6V0D1, ATP6V0E1, ATP6V1A, ATP6V1C2, BAIAP2, BCAR1, BMP7, BRIP1, CAV2, CDC6, CDK4, CEACAM1, CFLAR, CPS1, CSK, CSRP3, EDNRB, EEF2K, EIF2B5, EIF4EBP1, F7, FABP3, FER, FOXO1, FOXO3, FOXO6, FYN, GHRHR, GJB2, GRB14, GRB7, GSK3B, HDAC9, HSD11B2, HSF1, ICAM1, IGF1R, IGFBP1, INPPL1, INSR, KBTBD2, LPIN1, LPIN2, LPIN3, MAX, MTOR, MYO5A, NFE2L2, PAK1, PARP1, PCSK9, PDK2, PDK4, PDPK1, PIK3CA, PIK3R1, PIK3R2, PIK3R3, PKLR, POR, PPARG, PRKAR1B, PRKCD, PRKCI, PRKCZ, PRLR, PTK2, PTPN1, PTPRA, PXN, RAB10, RANGAP1, SCAP, SLC25A33, SOGA1, SORBS1, SORT1, SRC, SREBF1, SRSF5, STAR, STAT5A, STAT5B, TBC1D4, TCIRG1, TSC1, VAMP2, VGF, ZBTB7B, ZNF106"
GO:0007015,actin filament organization,216,0.003,0.907,"ABL1, ACTN1, ACTN4, ADD1, ADD2, ADD3, AIF1L, ANG, ARAP1, ARHGAP12, ARHGAP25, ARPC1B, BAIAP2, BAIAP2L2, BCAR1, BCL2, CFL1, CGNL1, COBL, CORO1C, CORO7, CUL3, DMTN, ENAH, EVL, FAM107A, FAM171A1, FMN2, FSCN1, GSN, HSP90B1, INPPL1, ITGB5, LIMA1, MAD2L2, MICAL3, MYO1B, MYOM3, NEB, NEDD9, PDLIM3, PPP1R9A, PPP1R9B, PREX1, PRKCI, PROX1, RHOBTB1, RHOBTB2, RHOF, RND2, SH3BP1, SORBS1, SORBS2, SORBS3, SPIRE1, SPIRE2, SRC, TCAP, TPM2, WASL, WDR1"
GO:0007411,axon guidance,248,0.003,0.925,"AGRN, APBB2, BCL11B, BMP7, DRGX, EFNA3, EFNA4, EFNB2, ENAH, EPHA10, EPHA4, EPHA8, EPHB2, EPHB3, EVL, EXT1, FAM129B, FEZ2, FRS2, FYN, GAB2, GLI2, GPC1, GRB7, HOXA2, KIF5B, KLF7, LGR6, LYPLA2, MAPK1, MAPK3, MATN2, NFASC, NRCAM, NRXN3, PAX6, PDLIM7, PIK3CA, PIK3CB, PIK3R1, PLXNA1, PLXNA2, PLXNB2, PLXNC1, PRKCA, PTCH1, PTK2, PTPRA, PTPRO, RAP1GAP, RNF165, SEMA3A, SEMA3B, SEMA3C, SEMA3F, SEMA6A, SHC3, SIAH1, SLIT1, SMAD4, SPTAN1, SPTBN1, SPTBN2, SPTBN5, SRC, TRIO, UNC5D, VEGFA"
GO:0061008,hepaticobiliary system development,122,0.003,0.995,"AACS, ACAT1, AK4, ALDH1A2, ARID5B, CCDC40, COBL, CPS1, CUL3, DDX39B, DNAAF1, E2F8, EGFR, EZH2, FPGS, HLX, HMOX1, HNF1A, HNF4A, IGF2R, ITGA2, JARID2, KRAS, MAN2A1, NIPBL, NOTCH1, PCSK9, PDX1, PHF2, PIK3CA, PKD1, PROX1, PTCH1, RAP1A, RARA, SMAD3, SP3, SRSF5, SULF2, UPF2"
GO:0032970,regulation of actin filament-based process,365,0.003,0.945,"ABL1, ABL2, ADD1, ADD2, ADD3, AKAP13, ALOX15, ARAP1, ARHGAP18, ARHGAP44, ARHGDIA, ARHGEF10L, ARPC1B, ATP1A1, ATP2A2, AVIL, BAIAP2, BAIAP2L2, BCAS3, BIN1, CAMK2D, CAPG, CAPZB, CCDC88A, CCL24, CDC42EP4, CDC42EP5, CDK10, CFL1, CLASP1, CNN2, DLC1, DMTN, EVL, F2RL1, FAM107A, FER, FES, FSCN1, GATA4, GSN, ICAM1, JUP, KANK1, KCNE3, KCNJ2, LIMA1, LIMCH1, LPAR1, MLST8, MTOR, MYADM, MYO1C, NEB, NF2, ODAM, PAK1, PAM, PDE4D, PDGFA, PHLDB2, PHPT1, PIK3R1, PPP1R9A, PREX1, PRKCD, PRKCE, PROX1, PXN, RASA1, RHOBTB1, RHOBTB2, RHOF, RICTOR, RND2, SH3BP1, SH3PXD2B, SMAD3, SMAD4, SORBS3, SPIRE1, SPIRE2, SPTAN1, SPTBN1, SPTBN2, SPTBN5, SYNPO, TRIOBP, TRPM4, TSC1, VILL, WASL, WDR1"
GO:1903829,positive regulation of cellular protein localization,318,0.003,0.976,"ABCA7, AGR2, AKT2, ANK3, ANP32B, ARHGEF16, ATG13, BAD, BAP1, BBC3, BCAS3, BCL2, BICD1, CACNB3, CARD10, CASP8, CCDC88A, CDH1, CNST, CROCC, CYLD, DMAP1, EGFR, EPHB2, FBXW7, FYN, FZD5, GLIS2, GSK3B, ITGA3, JUP, KAT7, KIF5B, LRP4, MAP1A, MAPK1, MAPK14, MARK4, MYO1C, NIPBL, NKD2, NMD3, NMT1, NPEPPS, NUMA1, PAK1, PARP1, PCNT, PDPK1, PDZK1, PIK3R1, PIK3R2, PPP1R13B, PPP1R9B, PPP3CC, PRKCD, PRKCE, PRKCH, PRKCI, RER1, RTN4, SAE1, SLC51B, SMAD3, SNX33, SORBS1, SORL1, SPTBN1, SQSTM1, SRC, STK11, TCF7L2, TFDP2, TGFB1, TP63, TP73, UBE2D3, UBR5, USP36, VAMP2, YWHAE, ZIC1"
GO:0048514,blood vessel morphogenesis,389,0.003,0.966,"AAMP, ACVRL1, ADAM15, ADAM8, ADTRP, AMOTL2, ANG, ANGPT2, ANPEP, ANXA2, APOLD1, ARID2, BCAS3, BMPR1A, CCM2, CDH13, CEACAM1, CHD7, COL18A1, COL4A1, DAB2IP, DLL1, DYSF, E2F8, EFNB2, ENPEP, EPHB2, EPHB3, ETS1, FBXW7, FGF1, FGF2, FGF9, FGFR1, FGFR2, FOLR1, FZD5, HDAC7, HEY1, HIF3A, HMOX1, HOXA3, HOXA7, HPGD, HSPG2, ITGAV, JAG1, LAMA5, LEF1, LEPR, LRP5, LRP5L, MAPK14, MMRN2, MYLK, MYO1E, NCL, NOTCH1, NPRL3, NRARP, NRCAM, OVOL2, PDCD6, PDGFA, PGF, PIK3CA, PIK3CB, PIK3R3, POFUT1, PRCP, PRKCA, PRKD2, PROX1, PRRX1, PTK2, RASA1, RECK, SETD2, SHB, SMAD7, SRPK2, STRA6, TBX20, TBX4, TDGF1, TFAP2B, TGFB1, THBS1, TIE1, TNFSF12, UBP1, VAV2, VEGFA, VEZF1, YAP1, ZMIZ1"
GO:0060828,regulation of canonical Wnt signaling pathway,272,0.003,0.921,"AES, AXIN1, AXIN2, BICC1, BMP2, BTRC, CDH3, CSNK1D, CUL3, CYLD, DAB2IP, DVL2, EGFR, FAM53B, FGF9, FGFR2, FOLR1, FOXO1, GNAQ, GSK3B, HDAC1, IGFBP1, JADE1, JUP, KANK1, KREMEN1, LGR4, LGR5, LGR6, LRP4, LYPD6, MAD2L2, MAPK14, MESP1, MLLT3, NKD1, NKD2, NOTCH1, NOTUM, NRARP, PPP1CA, PSMB10, PSMD11, PSMD3, PTK7, PTPRO, RAPGEF1, RECK, RNF220, ROR2, RUVBL1, SIAH2, SLC9A3R1, SMAD3, SRC, STK11, STK3, SULF2, TCF7L2, TLE3, TMEM88, TNKS, TRPM4, UBAC2, UBR5, USP34, WNK2, WNT10B, WNT5B, WWTR1, YAP1, ZNRF3"
GO:0035023,regulation of Rho protein signal transduction,135,0.003,0.522,"ABL1, ABL2, ABR, AKAP13, ARHGDIA, ARHGEF10L, ARHGEF16, ARHGEF26, ARHGEF28, ARHGEF3, ARHGEF39, ARHGEF4, ARHGEF40, ARHGEF7, BCR, CUL3, DLC1, DNMBP, EPS8L2, F2R, F2RL1, FARP1, FARP2, FGD3, FGD6, FLCN, GPR35, ITGA3, KANK1, KANK2, LPAR1, MCF2L2, NET1, NGEF, PLEKHG1, PLEKHG5, PREX1, RAF1, TIAM1, TRIO, VAV1, VAV2"
GO:0032535,regulation of cellular component size,352,0.003,0.939,"ABL1, ADD1, ADD2, ADD3, ALOX15, ANAPC2, AQP1, ARHGAP18, ARPC1B, AVIL, BAIAP2, BAIAP2L2, BARHL2, BIN1, CAPG, CAPZB, CCL24, CDC42EP4, CDC42EP5, CDHR2, CDHR5, CDK4, CFL1, CLNS1A, CRABP2, DMTN, E2F4, EVL, F2RL1, FER, GNB3, GSK3B, GSN, ICAM1, KANK1, KCNMA1, LIMA1, MAG, MLST8, MTOR, MYADM, MYO1C, NEB, NRCAM, PAK1, PICALM, PPP1CA, PPP1R9A, PREX1, PRKCD, PRKCE, RAB21, RAP1GAP2, RASA1, RICTOR, RILP, RND2, RPTOR, RTN4, SCT, SCTR, SEMA3A, SEMA3B, SEMA3C, SEMA3F, SEMA4B, SEMA4C, SEMA6A, SH3BP1, SIN3A, SLC12A2, SLC12A4, SLC12A5, SLC12A7, SLC12A8, SLC9A3R1, SPIRE1, SPIRE2, SPTAN1, SPTBN1, SPTBN2, SPTBN5, TRIOBP, TSC1, VAV1, VAV2, VEGFA, VILL, WASL, WDR1"
GO:0001889,liver development,119,0.003,0.995,"AACS, ACAT1, AK4, ALDH1A2, ARID5B, CCDC40, COBL, CPS1, CUL3, DDX39B, DNAAF1, E2F8, EGFR, EZH2, FPGS, HLX, HMOX1, HNF1A, HNF4A, IGF2R, ITGA2, JARID2, KRAS, MAN2A1, NOTCH1, PCSK9, PDX1, PHF2, PIK3CA, PKD1, PROX1, PTCH1, RAP1A, RARA, SMAD3, SP3, SRSF5, SULF2, UPF2"
GO:0097485,neuron projection guidance,251,0.004,0.925,"AGRN, APBB2, BCL11B, BMP7, DRGX, EFNA3, EFNA4, EFNB2, ENAH, EPHA10, EPHA4, EPHA8, EPHB2, EPHB3, EVL, EXT1, FAM129B, FEZ2, FRS2, FYN, GAB2, GLI2, GPC1, GRB7, HOXA2, KIF5B, KLF7, LGR6, LYPLA2, MAPK1, MAPK3, MATN2, NFASC, NRCAM, NRXN3, PAX6, PDLIM7, PIK3CA, PIK3CB, PIK3R1, PLXNA1, PLXNA2, PLXNB2, PLXNC1, PRKCA, PTCH1, PTK2, PTPRA, PTPRO, RAP1GAP, RNF165, SEMA3A, SEMA3B, SEMA3C, SEMA3F, SEMA6A, SHC3, SIAH1, SLIT1, SMAD4, SPTAN1, SPTBN1, SPTBN2, SPTBN5, SRC, TRIO, UNC5D, VEGFA"
GO:0060491,regulation of cell projection assembly,197,0.004,0.909,"AGRN, ARAP1, ARHGAP44, ATP8B1, AUTS2, BCAS3, CAPZB, CCDC88A, CCL19, CDC42EP4, CDC42EP5, CDK10, CDKL1, COBL, CORO1C, CROCC, CYLD, DMTN, EPS8L2, EVL, F2RL1, FER, FSCN1, HDAC4, HTT, ICAM1, KANK1, KCTD17, MARK4, MTOR, NEURL1, PALM, PPP1R16B, PPP1R9A, PRKCD, RABEP2, RABGAP1, RAP1GAP, RCC2, SEPT9, SH3YL1, SRC, SYNE2, TBC1D1, TBC1D10B, TBC1D14, TBC1D16, TBC1D2, TBC1D22A, TBC1D24, TBC1D2B, TBC1D5, TBC1D8, TCHP, TENM2, WASL, WRAP73"
GO:0035107,appendage morphogenesis,141,0.004,0.947,"AFF3, ALDH1A2, BMP7, BMPR1A, C2CD3, CHD7, CRABP2, CREBBP, ECE1, FGF9, FGFR1, FGFR2, FRAS1, GLI2, GNA12, GRHL2, HDAC1, HOXD10, LEF1, LRP4, MBNL1, MSX2, NIPBL, NOTCH1, OSR2, PBX1, PBX2, PLXNA2, PRRX1, PTCH1, RECK, RNF165, ROR2, RUNX2, SEMA3C, SMAD4, TBX4, TFAP2B, TP63, TRAF3IP1, TULP3, ZNF219"
GO:0035108,limb morphogenesis,141,0.004,0.947,"AFF3, ALDH1A2, BMP7, BMPR1A, C2CD3, CHD7, CRABP2, CREBBP, ECE1, FGF9, FGFR1, FGFR2, FRAS1, GLI2, GNA12, GRHL2, HDAC1, HOXD10, LEF1, LRP4, MBNL1, MSX2, NIPBL, NOTCH1, OSR2, PBX1, PBX2, PLXNA2, PRRX1, PTCH1, RECK, RNF165, ROR2, RUNX2, SEMA3C, SMAD4, TBX4, TFAP2B, TP63, TRAF3IP1, TULP3, ZNF219"
GO:0007229,integrin-mediated signaling pathway,88,0.004,0.932,"ABL1, ADAM10, ADAM15, BCAR1, CCM2, CEACAM1, COL16A1, CUL3, DOCK1, FERMT3, FUT8, ITGA1, ITGA2, ITGA3, ITGA9, ITGAE, ITGAL, ITGAV, ITGB4, ITGB5, ITGB6, LAMA3, NEDD9, PTK2, RCC2, SRC, TEC, TLN1, VAV1"
GO:0002065,columnar/cuboidal epithelial cell differentiation,96,0.004,0.986,"ABL1, AGR2, BMP2, BMP6, CBFA2T2, CDK6, DLL1, FAM20C, FGFR1, FGFR2, GATA4, GATA5, HNF4A, HOXA5, JAG1, JAG2, LEF1, LRTOMT, MYO7A, NKX2-2, NOTCH1, PAX6, PDPK1, PDX1, PROX1, RARA, RFX3, RXRA, SLC9A3R1, SPDEF, TP63, TRIOBP, WDR77"
GO:0032956,regulation of actin cytoskeleton organization,323,0.005,0.935,"ABL1, ABL2, ADD1, ADD2, ADD3, AKAP13, ALOX15, ARAP1, ARHGAP18, ARHGAP44, ARHGDIA, ARHGEF10L, ARPC1B, AVIL, BAIAP2, BAIAP2L2, BCAS3, BIN1, CAPG, CAPZB, CCDC88A, CCL24, CDC42EP4, CDC42EP5, CDK10, CFL1, CLASP1, DLC1, DMTN, EVL, F2RL1, FAM107A, FER, FES, FSCN1, GSN, ICAM1, KANK1, LIMA1, LIMCH1, LPAR1, MLST8, MTOR, MYADM, MYO1C, NEB, NF2, ODAM, PAK1, PAM, PDGFA, PHLDB2, PHPT1, PIK3R1, PPP1R9A, PREX1, PRKCD, PRKCE, PROX1, PXN, RASA1, RHOBTB1, RHOBTB2, RHOF, RICTOR, RND2, SH3BP1, SH3PXD2B, SMAD3, SMAD4, SORBS3, SPIRE1, SPIRE2, SPTAN1, SPTBN1, SPTBN2, SPTBN5, SYNPO, TRIOBP, TSC1, VILL, WASL, WDR1"
GO:0060390,regulation of SMAD protein signal transduction,21,0.005,0.677,"BMP6, BMPR1A, CILP, NUP93, OVOL2, PARP1, RBPMS, SMAD4, SPTBN1, TGFB1, WWTR1"
GO:1903392,negative regulation of adherens junction organization,21,0.005,0.789,"ACVRL1, BCAS3, BMP6, CORO1C, DLC1, DMTN, FAM107A, PHLDB2, RCC2, SRC, THBS1, VEGFA"
GO:0120032,regulation of plasma membrane bounded cell projection assembly,195,0.005,0.91,"AGRN, ARAP1, ARHGAP44, ATP8B1, AUTS2, BCAS3, CAPZB, CCDC88A, CCL19, CDC42EP4, CDC42EP5, CDK10, CDKL1, COBL, CORO1C, CROCC, CYLD, DMTN, EPS8L2, EVL, F2RL1, FER, FSCN1, HDAC4, HTT, ICAM1, KANK1, KCTD17, MARK4, MTOR, NEURL1, PALM, PPP1R16B, PPP1R9A, PRKCD, RABEP2, RABGAP1, RAP1GAP, RCC2, SEPT9, SH3YL1, SYNE2, TBC1D1, TBC1D10B, TBC1D14, TBC1D16, TBC1D2, TBC1D22A, TBC1D24, TBC1D2B, TBC1D5, TBC1D8, TCHP, TENM2, WASL, WRAP73"
GO:0042476,odontogenesis,118,0.006,0.961,"ANKRD11, AQP1, AXIN2, BCL11B, BMP2, BMP7, BMPR1A, CNNM4, CTNNA1, EDAR, FAM20A, FAM20C, FGFR2, FOXO1, GLI2, HDAC1, ID3, ITGB4, JAG2, KLK5, LEF1, LRP4, MSX2, MYO5A, NF2, NFIC, ODAM, OSR2, PAM, RELT, RUNX2, SDC1, SRC, STIM1, TCIRG1, TP63, TSPEAR"
GO:0090630,activation of GTPase activity,86,0.006,0.0672,"ABR, AKT2, ARHGEF16, BCAS3, BCR, CORO1C, MTSS1L, NEDD9, RABGAP1, RABGAP1L, RALGAPA1, RALGAPA2, RANGAP1, RAPGEF1, RASGRP1, RCC2, SIPA1L1, TBC1D1, TBC1D10B, TBC1D14, TBC1D16, TBC1D2, TBC1D22A, TBC1D2B, TBC1D4, TBC1D5, TBC1D8, TBC1D9, TIAM1, TSC1"
GO:0007044,cell-substrate junction assembly,41,0.006,0.669,"ACTN1, ARHGEF7, BCL2, BCR, COL17A1, DLC1, ITGA2, ITGB4, LAMA3, LAMA5, LAMB3, PDPK1, PEAK1, PLEC, PTPRK, RCC2, SORBS1, TLN1"
GO:0006656,phosphatidylcholine biosynthetic process,31,0.007,0.535,"ABHD3, CEPT1, CHKB, CHPT1, CSNK2A1, LCAT, LPIN1, LPIN2, LPIN3, PEMT, SLC44A1, SLC44A3, SLC44A4, STARD10, STARD7"
GO:0048762,mesenchymal cell differentiation,145,0.007,0.992,"ACVRL1, ADAM15, AKNA, ALDH1A2, BCL2, BMP2, BMP7, BMPR1A, CFL1, CORO1C, DLG5, EDN3, EDNRB, FBXL17, FGFR1, FGFR2, FOLR1, GSK3B, HEY1, JAG1, KITLG, LAMA5, LEF1, MAPK1, MAPK3, MSX2, NOTCH1, NRG1, OVOL2, PDCD4, PDCD6, RTN4, SEMA3A, SEMA3B, SEMA3C, SEMA3F, SEMA4B, SEMA4C, SEMA6A, SMAD4, SOX8, TGFB1, WNT2, WWTR1"
GO:0010976,positive regulation of neuron projection development,276,0.007,0.946,"ABL2, AGT, ANAPC2, ANKRD27, APBB1, ARHGDIA, AVIL, BAIAP2, BMP7, CAMK1D, CAMK2B, CBFA2T2, CFLAR, COBL, CPEB3, CPNE5, CRABP2, CUX1, DAB2IP, DDX56, DLG5, DVL2, EEF2K, EP300, EPHA4, EZH2, FBXO31, FBXO38, FES, FGFR1, FOXO6, FYN, ITGA3, LPAR1, LRP8, LTK, MAP2K1, MAP6, MAPK6, MARK2, METRN, MTOR, NEDD4L, NEURL1, NFE2L2, NIN, OBSL1, OPA1, PAK1, PARP6, PLXNA1, PLXNA2, PLXNB2, PLXNC1, PPP1R9A, PRKCI, PTK7, PTPRD, RAB21, RAP1A, RAPGEF1, RAPGEF2, RND2, RNF157, ROR2, SF3A2, SHANK2, SMURF1, STK11, TIAM1, TRAK1, VEGFA"
GO:0032148,activation of protein kinase B activity,28,0.007,0.81,"ANG, CCDC88A, FGF1, INSR, MAPKAP1, MLST8, MTOR, NRG1, PDGFB, PDPK1, PRKCZ, PRR5, RICTOR, SRC"
GO:1905477,positive regulation of protein localization to membrane,120,0.008,0.98,"AGR2, AKT2, ANK3, ARHGEF16, BAD, BBC3, BCL2, CACNB3, CASP8, CNST, EGFR, EPHB2, FYN, ITGA3, KIF5B, LRP4, MYO1C, NKD2, NMT1, PAK1, PDPK1, PDZK1, PIK3R1, PPP1R13B, PPP1R9B, PPP3CC, PRKCE, PRKCH, PRKCI, RER1, SLC51B, SORBS1, SPTBN1, SQSTM1, TFDP2, TP63, TP73, YWHAE"
GO:0001952,regulation of cell-matrix adhesion,112,0.008,0.982,"ABL1, ACER2, ACVRL1, ADAM15, BCAS3, BCL2, CDH13, CDK6, CLASP1, COL16A1, CORO1C, DLC1, DMTN, FAM107A, GSK3B, HOXA7, JAG1, JUP, LIMCH1, NF2, NINJ1, PEAK1, PHLDB2, PIK3CB, PIK3R1, PRKCZ, PTK2, RASA1, RCC2, SKAP1, SMAD3, SRC, THBS1, TSC1, UTRN, VEGFA"
GO:0051153,regulation of striated muscle cell differentiation,112,0.008,0.992,"AKAP13, AKAP6, BCL2, BHLHE41, BMP2, CAPN2, CFLAR, DDX39B, DLL1, DMPK, EFNB2, EHD1, EHD2, EZH2, FAM129B, FBXO22, FRS2, HDAC1, HDAC4, HDAC9, MAPK14, MESP1, MTOR, NFATC2, NOTCH1, NRG1, PAK1, PI16, PROX1, RBM24, RBM38, SMAD4, SOX6, TGFB1, TRIM32"
GO:0061138,morphogenesis of a branching epithelium,151,0.009,0.999,"BCL2, BMP2, BMP7, BTRC, COL4A1, DLG5, ESRP2, FGF1, FGF2, FGFR1, FGFR2, FRS2, FZD5, GCM1, GLI2, GRHL2, HOXA5, HOXD11, KRAS, LAMA5, LEF1, LRP5, LRP5L, MSX2, NOTCH1, NRARP, PAK1, PBX1, PGF, PKD1, PLXNA1, PPP1CA, PROX1, PTCH1, SEMA3A, SEMA3C, SMAD4, SOX8, SRC, ST14, TBX20, TP63, VDR, VEGFA, YAP1"
GO:0010810,regulation of cell-substrate adhesion,200,0.009,0.964,"ABL1, ACER2, ACTN4, ACVRL1, ADAM15, AGR2, ALOX15, ANGPT2, ARHGEF7, BCAS3, BCL2, CDH13, CDK6, CLASP1, COL16A1, CORO1C, DLC1, DMTN, DOCK1, FAM107A, GSK3B, HOXA7, ITGA3, JAG1, JUP, KANK1, LIMCH1, MYADM, NEDD9, NF2, NINJ1, NOTCH1, OLFM4, PEAK1, PHLDB2, PIK3CB, PIK3R1, PREX1, PRKCE, PRKCZ, PTK2, PTPRO, RASA1, RCC2, RREB1, SKAP1, SMAD3, SMOC2, SPOCK2, SRC, THBS1, TRIOBP, TSC1, UTRN, VEGFA"
GO:0007178,transmembrane receptor protein serine/threonine kinase signaling pathway,191,0.009,0.941,"ACVR1B, ACVR2A, ACVRL1, APPL2, BMP2, BMP6, BMP7, BMPR1A, FAM83G, FKBP1A, FSTL1, FURIN, FUT8, HIPK2, HNF4A, HPGD, INHA, ITGB5, LEF1, LEFTY1, LNPEP, LTBP1, LTBP3, MAP3K7, MAPK14, MAPK3, MSX2, NLK, NUP93, PARD3, PARP1, PDCD4, PRKCZ, PTK2, PTPRK, PXN, RGMB, RNF111, ROR2, RUNX2, SLC39A5, SMAD1, SMAD2, SMAD3, SMAD4, SMAD6, SMAD7, SMURF1, SPTBN1, SRC, TDGF1, TGFB1, UBE2D3, ZFYVE9"
GO:0050773,regulation of dendrite development,147,0.009,0.941,"ADAM10, ANAPC2, ANKRD27, ARHGAP44, BAIAP2, BCL11A, BMP7, CAMK1D, CAMK2B, CFL1, COBL, CPEB3, CUX1, DAB2IP, DLG5, EEF2K, EPHA4, EZH2, FBXO31, FOXO6, GSK3B, HECW2, LPAR1, LRP8, LZTS3, MAPK6, MTOR, NEDD4L, NEURL1, NGEF, NSMF, OBSL1, OPA1, PARP6, PPP1R9A, PPP3CA, PREX1, PTPRD, RAB21, RAPGEF2, SHANK2, SIPA1L1, STK11, TIAM1"
GO:0070482,response to oxygen levels,360,0.009,0.988,"ABAT, ACTN4, ACVRL1, ADAM15, ADAM8, AK4, ALAD, ANG, ANGPT2, APOLD1, AQP1, ARNT, ATP6V0D1, ATP6V1A, B3GAT1, BAD, BCL2, BMP2, BMP7, BNIP3, BRIP1, CA9, CACNB3, CAPN2, CARD16, CASP3, CBFA2T3, CDK4, CFLAR, CPEB4, CREBBP, DNMT3A, DPP4, EEF2K, EIF4EBP1, EP300, ETS1, F7, FMN2, FOXO1, GNB1, HIF3A, HIPK2, HMOX1, HSD11B2, HSF1, HSP90B1, ICAM1, ITGA2, ITPR2, KCNK3, KCNMA1, LMNA, LONP1, LPAR1, MIR106B, MTHFR, MTOR, MYB, NDRG1, NFE2L2, NOTCH1, NPEPPS, OPA1, P4HB, PAK1, PAM, PDK1, PGF, PKLR, PLAT, POLB, POLG, PPARG, PRKCE, PSMB10, PSMD11, PSMD3, RAF1, SCAP, SIRT2, SLC29A1, SMAD3, SMAD4, SRC, THBS1, TSC1, VEGFA, WTIP"
GO:0042063,gliogenesis,210,0.01,0.987,"ABCA2, ABL1, ADAM22, AKT2, BACE2, BNIP3, CDK6, CLU, CNTNAP1, CSK, DAB2IP, DLL1, DTX1, DUSP10, EGFR, EIF2B5, EPHA4, GCM1, GPC1, GSN, HDAC11, IL33, IL34, KRAS, LEF1, LEPR, LGI4, LPAR1, MAG, MAP2K1, MAPK1, MAPK3, MATN2, MBOAT7, METRN, MXRA8, MYRF, NDRG1, NF2, NKX2-2, NOTCH1, NRG1, P2RY1, PARD3, PAX6, PHGDH, PRDM8, ROR2, RTN4, SH3TC2, SIRT2, SOX6, SOX8, SUN1, SUN2, SYNE2"
GO:0001953,negative regulation of cell-matrix adhesion,39,0.01,0.806,"ACER2, ACVRL1, ADAM15, BCAS3, CORO1C, DLC1, DMTN, FAM107A, HOXA7, JAG1, NF2, PHLDB2, PIK3R1, RASA1, RCC2, SRC, THBS1"
GO:0071496,cellular response to external stimulus,308,0.01,0.98,"ADORA2B, AES, AGT, AKR1C3, AMBRA1, AOC1, AQP1, AQP2, ATP1A1, ATP2B1, BAD, BAIAP2, BCL11A, BCL2, BMP6, BNIP3, BRIP1, CACNB3, CASP1, CASP8, CBS, CLEC16A, CNN2, COMT, CPEB4, CYP24A1, DAP, EGFR, EHMT2, FAM107A, FBXO22, FES, FOLR1, FOXO1, FYN, GAS2L1, HDAC4, HMOX1, HSF1, HSP90B1, ICAM1, ITGA2, KCNJ2, KCNK4, KIAA1324, LTBR, MAG, MAP1LC3B2, MAP3K14, MAP3K5, MAPK1, MAPK3, MAX, MTOR, NCOA1, NFE2L2, NPRL3, NUAK2, OPA1, P2RY1, PCSK9, PDK2, PDK4, PIEZO1, PPARG, PPP1R9B, RPTOR, SESN1, SIPA1, SLC1A2, SLC38A3, SLC39A5, SREBF1, SZT2, TNKS, TRPM4, TSC1, UPP1, USF2, VDR"
GO:0030326,embryonic limb morphogenesis,122,0.01,0.955,"AFF3, ALDH1A2, BMP7, BMPR1A, C2CD3, CHD7, CRABP2, CREBBP, ECE1, FGF9, FGFR1, FRAS1, GLI2, GNA12, GRHL2, HDAC1, HOXD10, LEF1, LRP4, MBNL1, MSX2, NIPBL, NOTCH1, OSR2, PBX1, PBX2, PRRX1, PTCH1, RECK, ROR2, RUNX2, SMAD4, TBX4, TP63, TRAF3IP1, TULP3"
GO:0035113,embryonic appendage morphogenesis,122,0.01,0.955,"AFF3, ALDH1A2, BMP7, BMPR1A, C2CD3, CHD7, CRABP2, CREBBP, ECE1, FGF9, FGFR1, FRAS1, GLI2, GNA12, GRHL2, HDAC1, HOXD10, LEF1, LRP4, MBNL1, MSX2, NIPBL, NOTCH1, OSR2, PBX1, PBX2, PRRX1, PTCH1, RECK, ROR2, RUNX2, SMAD4, TBX4, TP63, TRAF3IP1, TULP3"
GO:0018212,peptidyl-tyrosine modification,148,0.01,0.924,"ABL1, ABL2, CSK, DYRK2, DYRK3, DYRK4, EGFR, EPHA10, EPHA4, EPHA8, EPHB2, EPHB3, FER, FES, FGFR1, FGFR2, FGFR3, FGFR4, FYN, HIPK2, HIPK3, IGF1R, INSR, LTK, MAP2K1, MAP2K3, MAP2K5, MAP2K6, MAPK3, PDGFB, PEAK1, PRKCD, PRLR, PTK2, PTPN6, ROR2, SRC, STYK1, TEC, TIE1, TNK2, TPST1, TPST2, YES1"
GO:1903391,regulation of adherens junction organization,65,0.01,0.875,"ABL1, ACVRL1, ADD1, BCAS3, BMP6, CLASP1, COL16A1, CORO1C, DLC1, DMTN, FAM107A, IQSEC1, LIMCH1, MAPRE2, PEAK1, PHLDB2, PTK2, PTPN23, RCC2, SMAD3, SRC, THBS1, TSC1, VEGFA"
GO:0034505,tooth mineralization,14,0.01,0.477,"CNNM4, FAM20A, FAM20C, FOXO1, MSX2, STIM1, TCIRG1, TSPEAR"
GO:0030834,regulation of actin filament depolymerization,50,0.01,0.742,"ADD1, ADD2, ADD3, AVIL, CAPG, CAPZB, CFL1, DMTN, F2RL1, GSN, LIMA1, SH3BP1, SPTAN1, SPTBN1, SPTBN2, SPTBN5, TRIOBP, VILL, WDR1"
GO:0042475,odontogenesis of dentin-containing tooth,81,0.01,0.869,"ANKRD11, BCL11B, BMP2, BMP7, BMPR1A, CNNM4, CTNNA1, EDAR, FAM20A, FAM20C, FOXO1, GLI2, HDAC1, ITGB4, JAG2, KLK5, LEF1, LRP4, MSX2, NF2, NFIC, ODAM, RELT, RUNX2, STIM1, TCIRG1, TP63"
GO:0045666,positive regulation of neuron differentiation,357,0.01,0.944,"ABL2, AGT, ANAPC2, ANKRD27, APBB1, ARHGDIA, AVIL, BAIAP2, BCL2, BMP2, BMP6, BMP7, CAMK1D, CAMK2B, CBFA2T2, CFLAR, COBL, CPEB3, CPNE5, CRABP2, CSNK1D, CSNK1E, CUX1, DAB2IP, DDX56, DLG5, DVL2, EEF2K, EP300, EPHA4, EZH2, FBXO31, FBXO38, FES, FGFR1, FOXO6, FYN, GDPD5, GLI2, HMG20B, ITGA3, LPAR1, LRP8, LTK, MAP2K1, MAP6, MAPK6, MARK2, METRN, MTOR, NCOA1, NEDD4L, NEURL1, NFE2L2, NIN, NKX2-2, NRCAM, OBSL1, OPA1, PAK1, PARP6, PLXNA1, PLXNA2, PLXNB2, PLXNC1, PPP1R9A, PRKCI, PROX1, PTK7, PTPRD, RAB21, RAP1A, RAPGEF1, RAPGEF2, RARA, RND2, RNF157, ROR2, SF3A2, SHANK2, SIN3A, SMURF1, STK11, TIAM1, TIMP2, TRAK1, TRIM32, VEGFA"
GO:0031076,embryonic camera-type eye development,36,0.01,0.845,"ALDH1A2, ALDH1A3, ARID1A, BMP7, FRS2, FZD5, HIPK2, KDM2B, PAX6, PPP1R13L, PROX1, RARA, SP3, STRA6, TRAF3IP1, TULP3"
GO:0060485,mesenchyme development,207,0.01,0.991,"ACTA2, ACVRL1, ADAM15, AKNA, ALDH1A2, BCL2, BMP2, BMP7, BMPR1A, CFL1, CORO1C, DLG5, EDN3, EDNRB, EXOC4, FBXL17, FGF9, FGFR1, FGFR2, FOLR1, GATA4, GATA5, GSK3B, HEY1, HOXA5, JAG1, KITLG, LAMA5, LEF1, MAPK1, MAPK3, MESP1, MSX2, NOTCH1, NRG1, OVOL2, PDCD4, PDCD6, PTK7, RBM24, RTN4, SEMA3A, SEMA3B, SEMA3C, SEMA3F, SEMA4B, SEMA4C, SEMA6A, SMAD2, SMAD3, SMAD4, SOX8, TBX20, TGFB1, WNT2, WWTR1, YAP1"
GO:0046486,glycerolipid metabolic process,353,0.01,0.911,"ABHD12, ABHD3, ABHD6, AGMO, ALOX15, ANG, APOBR, CEPT1, CHKB, CHPT1, CISH, CPS1, CPT1A, CSNK2A1, DAGLA, DAGLB, DGAT1, DGKE, DGKQ, EFR3B, FAAH, FABP3, FAM126A, FAR1, FGF2, GNPAT, GPD1, HRASLS2, IMPA2, INPP4A, INPP4B, INPP5F, INPP5J, INPPL1, LCAT, LIPC, LIPE, LMF1, LPCAT3, LPIN1, LPIN2, LPIN3, MBOAT1, MBOAT7, MGLL, MOGAT2, MPPE1, MTMR9, NAPEPLD, OSBPL10, OSBPL5, PCSK9, PEMT, PGAP2, PGAP3, PGS1, PI4KA, PIGQ, PIGU, PIK3CA, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PIP5KL1, PISD, PITPNM2, PLA2G2A, PLA2G4D, PLB1, PLCE1, PLCH2, PLEKHA1, PLEKHA3, PLEKHA8, PNPLA3, RUFY1, SBF1, SERINC5, SH3YL1, SLC22A4, SLC44A1, SLC44A3, SLC44A4, STARD10, STARD7, SYNJ1, TTC7B"
GO:1901889,negative regulation of cell junction assembly,23,0.01,0.81,"ACE, ACVRL1, BCAS3, CORO1C, DLC1, DMTN, FAM107A, IKBKB, PHLDB2, RCC2, SRC, THBS1"
GO:0035303,regulation of dephosphorylation,203,0.01,0.818,"BMP2, CALM1, CD2BP2, CHRM5, CNST, CSRNP3, DLC1, DMPK, ELFN2, ELL, ENSA, FARP1, FKBP1A, GNAI2, GPATCH2, GSK3B, HSP90B1, HTT, IKBKB, ITGA1, ITGA2, MFHAS1, MTMR9, MTOR, MYO1D, NSMF, NUAK1, PCIF1, PHACTR3, PPP1R12A, PPP1R14B, PPP1R16A, PPP1R16B, PPP1R1B, PPP1R36, PPP1R37, PPP1R9B, PPP2R1B, PPP2R5C, PPP2R5E, PPP4R2, PRKCD, RCAN1, SFI1, SH2D4A, SLC39A10, SLC7A14, SMAD3, SMG6, SPPL3, SRC, TGFB1, TSC1, URI1, YWHAE"
GO:0001525,angiogenesis,301,0.01,0.95,"AAMP, ACVRL1, ADAM15, ADAM8, ADTRP, AMOTL2, ANG, ANGPT2, ANPEP, ANXA2, APOLD1, BCAS3, CDH13, CEACAM1, COL18A1, COL4A1, DAB2IP, DLL1, DYSF, E2F8, EFNB2, ENPEP, EPHB2, EPHB3, ETS1, FGF1, FGF2, FGF9, FGFR1, FGFR2, FZD5, HEY1, HIF3A, HMOX1, HOXA3, HOXA7, HSPG2, ITGAV, JAG1, LAMA5, LEF1, LEPR, MAPK14, MMRN2, NCL, NOTCH1, NRARP, NRCAM, OVOL2, PDCD6, PDGFA, PGF, PIK3CA, PIK3CB, PIK3R3, POFUT1, PRCP, PRKCA, PRKD2, PTK2, RECK, SETD2, SHB, SRPK2, TBX20, TBX4, TDGF1, THBS1, TIE1, TNFSF12, UBP1, VAV2, VEGFA, VEZF1"
GO:1905475,regulation of protein localization to membrane,181,0.01,0.982,"ADAM10, AGR2, AKT2, ANK3, ARHGAP44, ARHGEF16, BAD, BBC3, BCL2, CACNB3, CASP8, CNST, CSK, CSRP3, DMTN, EGFR, EPHB2, FYN, GOPC, GPC1, GSN, ITGA3, KIF5B, LRP4, MYO1C, NKD2, NMT1, NUMB, PAK1, PDPK1, PDZK1, PICALM, PIK3R1, PPP1R13B, PPP1R9B, PPP3CC, PRKCE, PRKCH, PRKCI, PRKCZ, RAP1A, RER1, SLC51B, SORBS1, SPTBN1, SQSTM1, TFDP2, TGFB1, TP63, TP73, YWHAE"
GO:0007183,SMAD protein complex assembly,7,0.01,0.527,"FKBP1A, SMAD1, SMAD2, SMAD3, SMAD4, TGFB1"
GO:0034351,negative regulation of glial cell apoptotic process,7,0.01,0.582,"DLL1, PRKCA, PRKCD, PRKCH, PRKCI, TRAF2"
GO:0038202,TORC1 signaling,7,0.01,0.381,"CARD11, CLEC16A, MLST8, MTOR, NPRL3, RPTOR"
GO:0099515,actin filament-based transport,7,0.01,0.494,"ACTN4, MYO1C, MYO5A, SUN2, SYNE2, WASL"
GO:0051147,regulation of muscle cell differentiation,168,0.01,0.986,"ABL1, AKAP13, AKAP6, BCL2, BHLHE41, BMP2, CAPN2, CFLAR, CTNNA1, DDX39B, DLL1, DMPK, DNMT1, EFNB2, EHD1, EHD2, EZH2, FAM129B, FBXO22, FGF9, FGFR2, FRS2, HDAC1, HDAC4, HDAC9, MAPK14, MEF2A, MESP1, MTOR, NFATC1, NFATC2, NFATC3, NOTCH1, NRG1, PAK1, PDCD4, PDGFB, PI16, PIAS1, PROX1, RBM24, RBM38, SMAD4, SOX6, SUPT6H, TGFB1, TRIM32"
GO:0000187,activation of MAPK activity,146,0.01,0.962,"ADORA2B, BMP2, CCL19, DAB2IP, ERN2, ERP29, FGF1, FGF2, FRS2, GNG3, INSR, ITGA1, LPAR1, MAP2K1, MAP2K3, MAP2K5, MAP2K6, MAP3K5, MAP3K7, MAP3K9, MAP4K2, MAP4K5, MAPK1, MAPK14, MAPK3, MAPK8IP3, MAPKAPK3, MUC20, NOD1, NRG1, PDE6G, PEA15, PIK3CB, PLCE1, PRDX2, PTPN1, S1PR2, TAB2, TDGF1, THBS1, TP73"
GO:0048863,stem cell differentiation,142,0.01,0.982,"ACE, ALDH1A2, BATF, BMPR1A, CDK6, CFL1, CORO1C, EDN3, EDNRB, EPCAM, FBXL17, FGFR2, FOLR1, HOXA7, JAG1, JARID2, KITLG, LAMA5, MAPK1, MAPK3, MSI2, MSX2, NOTCH1, NRG1, OVOL2, PDCD6, PDX1, PSMD11, PUM1, RUNX2, SEMA3A, SEMA3B, SEMA3C, SEMA3F, SEMA4B, SEMA4C, SEMA6A, SETD2, SMAD4, SOX8, TP63, XRCC5"
GO:1901888,regulation of cell junction assembly,87,0.01,0.885,"ABL1, ACE, ACVRL1, AGT, BCAS3, CLASP1, COL16A1, CORO1C, DLC1, DMTN, FAM107A, FZD5, GPBAR1, IKBKB, LIMCH1, MYO1C, PEAK1, PHLDB2, PRKCH, PTK2, RAP1A, RAPGEF1, RAPGEF2, RCC2, SMAD3, SRC, THBS1, TSC1, VEGFA"
GO:0008654,phospholipid biosynthetic process,233,0.01,0.908,"ABHD3, ALOX15, CEPT1, CHKB, CHPT1, CSNK2A1, DGKE, DGKQ, DHDDS, DOLPP1, FAR1, FDPS, FGF2, GNPAT, GPD1, HMGCS2, INPP4A, INPP4B, INPP5F, INPP5J, INPPL1, LCAT, LPCAT3, LPIN1, LPIN2, LPIN3, MBOAT1, MBOAT7, MPPE1, MTMR9, PEMT, PGAP2, PGAP3, PGS1, PI4KA, PIGQ, PIGU, PIK3CA, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PISD, PITPNM2, PLA2G2A, PLA2G4D, PLEKHA1, PLEKHA3, PLEKHA8, PNPLA3, RUFY1, SBF1, SERINC5, SH3YL1, SLC44A1, SLC44A3, SLC44A4, SPTLC2, STARD10, STARD7, SYNJ1, TMEM38B"
GO:1900076,regulation of cellular response to insulin stimulus,67,0.01,0.858,"AGT, APPL2, ATP2B1, CCND3, CDK4, ESRRA, GNAI2, GRB14, GRB7, KANK1, MYO1C, MZB1, OPA1, PAK1, PIK3R1, PRKCD, PRKCZ, PTPN1, SORBS1, SORL1, SRC, TSC1, ZBTB7B"
GO:0070166,enamel mineralization,12,0.01,0.477,"CNNM4, FAM20A, FAM20C, FOXO1, MSX2, STIM1, TCIRG1"
GO:0035690,cellular response to drug,328,0.01,0.996,"ABCC2, ABL1, ACER2, ADAM15, ADCY3, ADIRF, ADSSL1, AGRN, AOC1, AQP1, BAD, BAIAP2, BCL11A, BNIP3, CBX8, CDH1, CDK4, CFLAR, CHRM3, CHRM5, CTNNA1, DCPS, DDI2, DNMT3A, DPEP1, EGFR, EIF4EBP1, ETS1, EZH2, FOLR1, FOXO1, FXN, FYN, GJB2, GNA11, GNAI2, GNAQ, GNB1, GSTM2, HMOX1, HSF1, HSP90B1, ICAM1, ITPR2, JUP, KCNH2, KCNQ1, KDM6B, KLF9, MAP3K5, MAPK1, MAPK3, MTR, MYB, NET1, NFE2L2, NOD1, OPA1, P2RY1, PDE4A, PDGFB, PLEKHA1, PPP1R12A, PPP1R9B, PPP3CA, PPP5C, PRKCD, PRKCE, PTAFR, RAP1A, REN, RGS8, SIN3A, SMYD3, SPIDR, SRC, STAR, TFAP4, TMEM38B, TNFAIP3, TRAF2, TRPM4"
GO:0031929,TOR signaling,27,0.01,0.635,"CARD11, CCDC88A, CLEC16A, EIF4EBP1, FLCN, MAPKAP1, MLST8, MTOR, NPRL3, PRR5, RICTOR, RPTOR"
GO:0003013,circulatory system process,387,0.01,0.989,"ABAT, ABR, ACE, ACTA2, ACVRL1, ADORA2B, ADRA1B, ADRB3, AGT, AKAP13, ATP1A1, ATP2B1, AVPR1B, BCR, BMP6, C9orf3, CACNA1D, CACNA1G, CACNB2, CAMK2D, CEACAM1, CHD7, CHGA, CHRM3, CORIN, CPS1, CSRP3, DDAH1, DLL1, DOCK4, E2F4, ECE1, EDN3, EDNRB, EGFR, ENPEP, EPHX2, F2R, F2RL1, FYN, GNB3, HMOX1, HSD11B2, ICAM1, ITGA1, KCND3, KCNE3, KCNH2, KCNJ2, KCNMA1, KCNQ1, KLK2, LRP5, MAP2K3, MAP2K6, MTOR, NAV2, NCALD, NEDD4L, NMU, NPR2, P2RX1, P2RY1, PDE3A, PDE4D, PDGFB, PER2, PIK3CA, PLCB3, PLOD3, PPARG, PPP1R13L, PRCP, PTAFR, PTPRO, RCAN1, REN, RNLS, SGK1, SLC2A5, SMAD3, SNX5, SRC, SUCNR1, TBC1D8, TBX20, TCAP, TGFB1, TNNI2, TRPM4, VEGFA, WWTR1, YAP1, YES1"
GO:0051058,negative regulation of small GTPase mediated signal transduction,52,0.01,0.631,"ABL2, ARHGAP12, ARHGAP25, ARHGAP44, CGNL1, CUL3, DAB2IP, DLC1, EPHB2, FLCN, ITGA3, KANK1, MAPKAP1, MFN2, RAPGEF1, RASA2, RASA3, SH3BP1, SYNGAP1, TIMP2"
GO:0090092,regulation of transmembrane receptor protein serine/threonine kinase signaling pathway,234,0.01,0.948,"ABL1, ACVR1B, ACVR2A, ACVRL1, BCL9L, BMP2, BMP6, BMP7, BMPR1A, CAV2, CDKN1C, CILP, CREBBP, DACT2, EP300, FGF9, FKBP1A, FLCN, FOLR1, FSTL1, GATA4, GLG1, HIPK2, INHA, ITGA3, LDLRAD4, LEFTY1, LTBP1, MSX2, NOTCH1, NREP, NUMA1, NUP93, OVOL2, PARP1, PDPK1, PEG10, PMEPA1, PRDM16, RASL11B, RBPMS, RNF111, RNF165, SKOR1, SMAD2, SMAD3, SMAD4, SMAD6, SMAD7, SMURF1, SORL1, SPTBN1, STK11, TBX20, TFAP2B, TGFB1, THBS1, WFIKKN1, WWTR1, ZBTB7A, ZC3H3"
GO:0016055,Wnt signaling pathway,329,0.01,0.915,"AES, AGO2, AMOTL2, AP2A2, AXIN1, AXIN2, BCL9L, BTRC, CALM1, CCDC88C, CDH3, CSNK1D, CSNK1E, CSNK2A1, CTR9, CUL3, CYLD, DAAM1, DVL2, FAM53B, FZD5, GNB1, GRK5, GSK3B, HBP1, HIC1, HMGXB4, KREMEN1, LEF1, LGR4, LGR6, LRP4, LRP5, LRP5L, LRRFIP2, MAP3K7, MARK2, NDRG2, NFATC1, NKD1, NKD2, NLK, NOTUM, NXN, PDE6A, PDE6B, PDE6G, PKD1, PLCB2, PLCB3, PPP1CA, PPP3CA, PSMB10, PSMD11, PSMD3, PTK7, RECK, RNF138, ROR2, RTF1, SDC1, SLC9A3R1, SMURF1, STK11, TCF7L2, TIAM1, TLE3, TMEM88, TNKS, TNRC6B, TNRC6C, TRABD2B, USP34, VANGL1, WNT10B, WNT2, WNT5B, WWOX, ZNRF3"
GO:0198738,cell-cell signaling by wnt,329,0.01,0.915,"AES, AGO2, AMOTL2, AP2A2, AXIN1, AXIN2, BCL9L, BTRC, CALM1, CCDC88C, CDH3, CSNK1D, CSNK1E, CSNK2A1, CTR9, CUL3, CYLD, DAAM1, DVL2, FAM53B, FZD5, GNB1, GRK5, GSK3B, HBP1, HIC1, HMGXB4, KREMEN1, LEF1, LGR4, LGR6, LRP4, LRP5, LRP5L, LRRFIP2, MAP3K7, MARK2, NDRG2, NFATC1, NKD1, NKD2, NLK, NOTUM, NXN, PDE6A, PDE6B, PDE6G, PKD1, PLCB2, PLCB3, PPP1CA, PPP3CA, PSMB10, PSMD11, PSMD3, PTK7, RECK, RNF138, ROR2, RTF1, SDC1, SLC9A3R1, SMURF1, STK11, TCF7L2, TIAM1, TLE3, TMEM88, TNKS, TNRC6B, TNRC6C, TRABD2B, USP34, VANGL1, WNT10B, WNT2, WNT5B, WWOX, ZNRF3"
GO:0018209,peptidyl-serine modification,184,0.02,0.918,"AKT2, BCL2, C8orf44-SGK3, CAB39, CAMK2D, CSNK1D, CSNK1E, CSNK2A1, DCLK2, DGKQ, DMPK, DYRK2, DYRK3, DYRK4, GALNT3, GSK3B, HIPK2, HIPK3, IKBKB, KDELC2, MAPK1, MAPK14, MAPK3, MAPKAPK3, MARK2, MAST2, MAST3, MAST4, MGAT5B, MTOR, NLK, PARP1, PDGFB, PDPK1, PKD1, PRKCA, PRKCD, PRKCE, PRKCH, PRKCI, PRKCZ, PRKD2, RICTOR, SGK1, SPOCK2, SRC, STK38, TDGF1, TLK2, TNKS, VRK2"
GO:0097186,amelogenesis,21,0.02,0.442,"CNNM4, FAM20A, FAM20C, FOXO1, ITGB4, KLK5, MSX2, RELT, STIM1, TCIRG1"
GO:0045446,endothelial cell differentiation,80,0.02,0.875,"ACVRL1, ANXA2, ARHGEF26, CCM2, COL18A1, DLL1, F2RL1, HEY1, ICAM1, JAG1, KDM6B, LAMA5, MESP1, MYADM, NOTCH1, NRG1, PDE4D, PLOD3, PPP1R16B, PROX1, RAB1B, RAP1A, RAPGEF1, RAPGEF2, SMAD4, VEZF1"
GO:0060537,muscle tissue development,287,0.02,0.967,"AGT, AKAP13, ALDH1A2, ALPK2, ARID1A, ARID2, ASB2, BCL9L, BMP2, BMP7, BMPR1A, CAV2, CFLAR, CHD7, CSRP1, CSRP3, CXADR, DLL1, EP300, FGFR2, FKBP1A, FLNB, FOXP2, GATA4, GATA5, HIVEP3, HLX, HMG20B, HOXD10, KCNAB1, KDM6B, LMNA, MAPK14, MEF2A, MEF2D, MESP1, MTOR, MYH15, MYL6, MYLK, MYOM3, NEB, NEURL1, NOTCH1, NPRL3, NRG1, NUPR1, OBSL1, PAX7, PGM5, PPP1R13L, PPP3CA, PROX1, RARA, RBP4, RXRA, SEMA3C, SMAD4, SMAD7, SORBS2, SOX6, SOX8, STRA6, SVIL, TBX20, TCAP, TGFB1, TSC1, VEGFA, WNT10B, WNT2, ZFPM1"
GO:0051895,negative regulation of focal adhesion assembly,18,0.02,0.746,"ACVRL1, BCAS3, CORO1C, DLC1, DMTN, FAM107A, PHLDB2, RCC2, SRC, THBS1"
GO:0045017,glycerolipid biosynthetic process,208,0.02,0.907,"ABHD3, AGMO, ALOX15, ANG, CEPT1, CHKB, CHPT1, CSNK2A1, DGAT1, DGKQ, FAR1, FGF2, GNPAT, GPD1, INPP4A, INPP4B, INPP5F, INPP5J, INPPL1, LCAT, LPIN1, LPIN2, LPIN3, MOGAT2, MPPE1, MTMR9, PEMT, PGAP2, PGAP3, PGS1, PI4KA, PIGQ, PIGU, PIK3CA, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PISD, PITPNM2, PLA2G2A, PLA2G4D, PLCE1, PLEKHA1, PLEKHA3, PLEKHA8, PNPLA3, RUFY1, SBF1, SH3YL1, SLC44A1, SLC44A3, SLC44A4, STARD10, STARD7, SYNJ1"
GO:0048814,regulation of dendrite morphogenesis,89,0.02,0.935,"ADAM10, ANAPC2, ANKRD27, ARHGAP44, BAIAP2, CAMK2B, CFL1, CUX1, EEF2K, EPHA4, FBXO31, GSK3B, HECW2, LRP8, LZTS3, NEDD4L, NGEF, NSMF, OBSL1, OPA1, PARP6, PPP1R9A, PPP3CA, PTPRD, RAB21, RAPGEF2, SIPA1L1, STK11, TIAM1"
GO:0018108,peptidyl-tyrosine phosphorylation,145,0.02,0.924,"ABL1, ABL2, CSK, DYRK2, DYRK3, DYRK4, EGFR, EPHA10, EPHA4, EPHA8, EPHB2, EPHB3, FER, FES, FGFR1, FGFR2, FGFR3, FGFR4, FYN, HIPK2, HIPK3, IGF1R, INSR, LTK, MAP2K1, MAP2K3, MAP2K5, MAP2K6, MAPK3, PDGFB, PEAK1, PRKCD, PRLR, PTK2, PTPN6, ROR2, SRC, STYK1, TEC, TIE1, TNK2, YES1"
GO:0018105,peptidyl-serine phosphorylation,163,0.02,0.922,"AKT2, BCL2, C8orf44-SGK3, CAB39, CAMK2D, CSNK1D, CSNK1E, CSNK2A1, DCLK2, DGKQ, DMPK, DYRK2, DYRK3, DYRK4, GSK3B, HIPK2, HIPK3, IKBKB, MAPK1, MAPK14, MAPK3, MAPKAPK3, MARK2, MAST2, MAST3, MAST4, MTOR, NLK, PDGFB, PDPK1, PKD1, PRKCA, PRKCD, PRKCE, PRKCH, PRKCI, PRKCZ, PRKD2, RICTOR, SGK1, SRC, STK38, TDGF1, TLK2, TNKS, VRK2"
GO:0061448,connective tissue development,218,0.02,0.968,"AACS, ACAT1, ACTA2, ANXA2, ANXA6, ARID5B, AXIN2, BMP2, BMP6, BMP7, BMPR1A, CDK4, CHI3L1, COL11A2, EBF2, EPYC, ESRRA, FGF2, FGF9, FGFR1, FGFR3, FTO, GLI2, HOXA3, HOXA5, HYAL1, LRP5, LRP5L, MAPK14, MAPK3, MATN2, MEF2D, MSX2, MUSTN1, NOTCH1, OSR2, PAX7, PDGFB, PIK3CA, PKD1, PRRX1, PTH1R, RARA, ROR2, RORC, RUNX2, SH3PXD2B, SLC25A25, SOX6, SOX8, SPTLC2, SULF2, TGFB1, THRA, WNT10B, WNT5B, ZNF516"
GO:0006884,cell volume homeostasis,28,0.02,0.669,"ADD1, AQP1, CLNS1A, E2F4, GNB3, KCNMA1, SCT, SCTR, SLC12A2, SLC12A4, SLC12A5, SLC12A7, SLC12A8"
GO:0014706,striated muscle tissue development,275,0.02,0.967,"AGT, AKAP13, ALDH1A2, ALPK2, ARID1A, ARID2, ASB2, BCL9L, BMP2, BMP7, BMPR1A, CAV2, CFLAR, CHD7, CSRP3, CXADR, DLL1, EP300, FGFR2, FKBP1A, FLNB, FOXP2, GATA4, GATA5, HIVEP3, HLX, HMG20B, HOXD10, KCNAB1, KDM6B, LMNA, MAPK14, MEF2A, MEF2D, MESP1, MTOR, MYH15, MYL6, MYOM3, NEB, NEURL1, NOTCH1, NPRL3, NRG1, NUPR1, OBSL1, PAX7, PGM5, PPP1R13L, PPP3CA, PROX1, RARA, RBP4, RXRA, SEMA3C, SMAD4, SMAD7, SORBS2, SOX6, SOX8, SVIL, TBX20, TCAP, TGFB1, TSC1, VEGFA, WNT10B, WNT2, ZFPM1"
GO:0030832,regulation of actin filament length,168,0.02,0.919,"ADD1, ADD2, ADD3, ALOX15, ARHGAP18, ARPC1B, AVIL, BAIAP2, BAIAP2L2, BIN1, CAPG, CAPZB, CCL24, CDC42EP4, CDC42EP5, CFL1, DMTN, EVL, F2RL1, FER, GSN, ICAM1, KANK1, LIMA1, MLST8, MTOR, MYADM, MYO1C, NEB, PPP1R9A, PREX1, PRKCD, PRKCE, RASA1, RICTOR, SH3BP1, SPIRE1, SPIRE2, SPTAN1, SPTBN1, SPTBN2, SPTBN5, TRIOBP, VILL, WASL, WDR1"
GO:0072006,nephron development,115,0.02,0.999,"ACAT1, ACTA2, ANGPT2, AQP11, BCL2, BMP2, BMP7, DLL1, ENPEP, FGF1, FGF2, HOXD11, IRX1, ITGA3, JAG1, KLHL3, LAMA5, LGR4, MTSS1, MYO1E, NOTCH1, PBX1, PDGFB, PGF, PKD1, PLCE1, PROM1, PTCH1, PTPRO, SMAD4, SOX8, SULF2, TFAP2B, WNK4, WWTR1"
GO:0030835,negative regulation of actin filament depolymerization,35,0.02,0.586,"ADD1, ADD2, ADD3, AVIL, CAPG, CAPZB, DMTN, GSN, LIMA1, SPTAN1, SPTBN1, SPTBN2, SPTBN5, TRIOBP, VILL"
GO:0060612,adipose tissue development,35,0.02,0.783,"AACS, ACAT1, ARID5B, CDK4, EBF2, FTO, LRP5, LRP5L, PIK3CA, RORC, SH3PXD2B, SLC25A25, SOX8, SPTLC2, ZNF516"
GO:2001233,regulation of apoptotic signaling pathway,392,0.02,0.966,"AGT, BAD, BBC3, BCL2, BIRC6, BMF, BNIP3, C8orf44-SGK3, CASP8, CFLAR, CIDEB, CLU, CREB3L1, CSNK2A1, CTNNA1, CYLD, DAB2IP, DAPK2, DNAJA1, ERP29, FAIM2, FBXW7, FGFR1, FLCN, FXN, FYN, G0S2, GATA4, GNAI2, GSK3B, GSN, HDAC1, HMOX1, HTT, ICAM1, ITGAV, ITM2C, LGALS9, LMNA, LTBR, MAP2K5, MIR26B, MNT, NACC2, NFE2L2, NMT1, NOL3, NUPR1, OPA1, P4HB, PAM16, PARP1, PDIA3, PDX1, PEA15, PLAGL2, PPP1CA, PPP1R13B, PPP2R1B, PPP3CC, PRDX2, PRKCD, PRR7, PTPN1, QARS, RAD9A, RAF1, RTKN2, SH3RF1, SIAH1, SIAH2, SLC9A3R1, SMAD3, SRC, ST18, STK3, TCF7L2, TFAP4, TFDP2, THBS1, TMC8, TNFAIP3, TNFSF12, TP63, TP73, TRAF2, TRAP1, TRIM32, URI1, VNN1, WWOX, YAP1, YWHAE"
GO:0007162,negative regulation of cell adhesion,281,0.02,0.984,"ABAT, ABL1, ACER2, ACTN4, ACVRL1, ADAM10, ADAM15, ADAM22, ADTRP, AKNA, ANGPT2, ARG2, ARHGDIA, BCAS3, BMP2, BMP6, CASP3, CDH1, CDH13, CEACAM1, CLDN7, CORO1C, DACT2, DLC1, DLG5, DMTN, DTX1, EPCAM, FAM107A, HLX, HOXA7, JAG1, KANK1, LAG3, LGALS9, MAD2L2, MAP2K5, MBP, MUC21, MYADM, NF2, NOTCH1, NRARP, PAG1, PHLDB2, PIK3R1, PLA2G2A, PLXNA1, PLXNA2, PLXNB2, PLXNC1, PRDX2, PRKCD, PTK2, PTPN6, PTPRO, RASA1, RC3H1, RCC2, SEMA6A, SH2B3, SIPA1, SMAD7, SRC, TGFB1, THBS1, UBASH3B, VEGFA, ZBTB7B"
GO:0021537,telencephalon development,243,0.02,0.985,"ALDH1A3, AQP1, ARL13B, ATAT1, ATIC, BAD, BCAN, BCL11B, BMP2, BNIP3, CASP3, CDK6, CHD7, DAB2IP, DCLK2, EGFR, EIF2B5, EPHB2, EPHB3, EXT1, EZH2, FOXP2, FUT10, GNG12, GSK3B, HDAC1, IGF2BP1, KDM2B, KDM6B, KIF5B, LEF1, LPAR1, LRP8, MBOAT7, MCPH1, NCOA1, NF2, NIN, NRG1, NUMB, PAX6, PHLPP2, PPP1R9B, PROX1, RARA, RTN4, RTN4RL1, SCT, SEMA3A, SLC1A2, SLIT1, SUN1, SUN2, SYNE2, SZT2, TACC2, TRAPPC9, TSC1, TSKU, YWHAE, ZSWIM6"
GO:1900078,positive regulation of cellular response to insulin stimulus,25,0.02,0.757,"AGT, ESRRA, GNAI2, MYO1C, OPA1, PAK1, PRKCZ, SORBS1, SORL1, SRC, ZBTB7B"
GO:0048880,sensory system development,344,0.02,0.928,"ACVRL1, ALDH1A2, ALDH1A3, ARID1A, ATF6, ATP2B1, BCL11B, BFSP1, BMP6, BMP7, CDK4, CDKN1C, CHD7, COL4A1, CRYBA1, DLL1, EGFR, EPHB2, FGF9, FOXP2, FRS2, FZD5, GNAT1, GNB1, GRHL2, HDAC1, HIPK2, HSF4, JAG1, KDM2B, LIMK2, LRP5, LRP5L, MAN2A1, MAX, MFN2, MFRP, MYH15, MYO7A, NF2, NINJ1, NIPBL, NKD1, NRL, OPA1, OSR2, PAX6, PDE6A, PDE6B, PDE6C, PPP1R13L, PRKCI, PROM1, PROX1, RAB11FIP4, RARA, RBP4, RING1, ROM1, RXRA, SDK2, SEMA3A, SH3PXD2B, SIPA1L3, SLC25A25, SLC39A5, SLC44A4, SMAD3, SMG9, SMOC1, SOX8, SP3, STRA6, TCIRG1, TFAP2B, THRB, TRAF3IP1, TSKU, TULP3, VEGFA, WNT2, WNT5B, ZNF513"
GO:0030168,platelet activation,129,0.02,0.94,"ACTG1, ACTN1, CLIC1, CSRP1, DGKE, DGKQ, F2R, FERMT3, FIBP, FYN, GNA11, GNA12, GNA14, GNAQ, GNB1, GP5, ITPR2, MAPK1, MAPK3, P2RX1, P2RY1, PDPK1, PIK3CA, PIK3CB, PIK3R1, PRKCA, PRKCD, PRKCE, PRKCH, PTPN6, RAF1, SRC, STXBP1, TLN1, UBASH3B, VAV1, VAV2"
GO:0071229,cellular response to acid chemical,197,0.02,0.992,"ABL2, AKR1C3, ALDH1A2, AQP1, AQP2, BAIAP2, BCL11A, CAPN2, CDK4, COL16A1, COL4A1, CPEB3, CPEB4, CPS1, CPT1A, DNMT1, DNMT3A, EGFR, FGFR2, FOLR1, FYN, GNB1, HOXA2, HSF1, ID3, KCNK4, LTK, MTOR, MYB, NEURL1, NSMF, OPA1, PDGFB, PDK4, PPARG, PRKCE, PTAFR, PTK7, RARA, RPTOR, SESN1, SIPA1, SRC, SREBF1, TESC, UBR1, VEGFA, WNT10B, WNT2, WNT5B, XRCC5, YAP1, YES1"
GO:0001654,eye development,335,0.02,0.925,"ACVRL1, ALDH1A2, ALDH1A3, ARID1A, ATF6, ATP2B1, BCL11B, BFSP1, BMP6, BMP7, CDK4, CDKN1C, CHD7, COL4A1, CRYBA1, DLL1, EGFR, EPHB2, FGF9, FOXP2, FRS2, FZD5, GNAT1, GNB1, GRHL2, HDAC1, HIPK2, HSF4, JAG1, KDM2B, LIMK2, LRP5, LRP5L, MAN2A1, MAX, MFN2, MFRP, MYH15, MYO7A, NF2, NINJ1, NIPBL, NKD1, NRL, OPA1, OSR2, PAX6, PDE6A, PDE6B, PDE6C, PPP1R13L, PRKCI, PROM1, PROX1, RAB11FIP4, RARA, RBP4, RING1, ROM1, RXRA, SDK2, SH3PXD2B, SIPA1L3, SLC25A25, SLC39A5, SMAD3, SMG9, SMOC1, SOX8, SP3, STRA6, TCIRG1, TFAP2B, THRB, TRAF3IP1, TSKU, TULP3, VEGFA, WNT2, WNT5B, ZNF513"
GO:0051693,actin filament capping,32,0.02,0.579,"ADD1, ADD2, ADD3, AVIL, CAPG, CAPZB, DMTN, GSN, SPTAN1, SPTBN1, SPTBN2, SPTBN5, TRIOBP, VILL"
GO:0023014,signal transduction by protein phosphorylation,365,0.02,0.927,"ADORA2B, AGT, BTRC, CAB39, CAB39L, CALM1, CCL19, CCM2, CDC42EP5, CUL3, DAB2IP, EGFR, ERN2, FGF1, FGF19, FGF2, FGF9, FGFR1, FGFR2, FGFR3, FGFR4, FRS2, FYN, GRIN2B, HSF1, IKBKB, ITGAV, KITLG, KRAS, KSR1, LGALS9, MAP2K1, MAP2K3, MAP2K5, MAP2K6, MAP3K14, MAP3K5, MAP3K7, MAP3K9, MAP4K2, MAP4K3, MAP4K5, MAPK1, MAPK14, MAPK3, MAPK6, MAPK8IP3, MAPKAPK3, MBP, MEF2A, NLK, NOD1, NRAS, NRG1, PAK1, PAK6, PAQR3, PDGFA, PDGFB, PEA15, PEBP1, PPP5C, PSMB10, PSMD11, PSMD3, PTK2, PTPN1, PTPRA, RAF1, RAPGEF2, RASA1, RASA2, RASA3, RASGRP1, ROR2, SHC3, SPTAN1, SPTBN1, SPTBN2, SPTBN5, STK10, STK3, SYNGAP1, TAB2, TAOK3, TGFB1, YWHAE"
GO:0035272,exocrine system development,43,0.02,0.856,"BMP7, EDAR, EGFR, ESRP2, FGFR1, FGFR2, INSR, LAMA5, PAX6, PDX1, PLXNA1, POLB, RAB26, SEMA3A, SEMA3C, TFCP2L1, TGFB1"
GO:0030856,regulation of epithelial cell differentiation,143,0.02,0.98,"ACVRL1, ADD1, APOLD1, BAD, BMP6, CDKN1C, CEACAM1, DLL1, EZH2, GRHL2, GSK3B, H2AFY, HOXA7, IKBKB, JAG1, KEAP1, KLF7, MESP1, MSX2, NOTCH1, NUMA1, OVOL2, PAX6, PPP1R12A, PRKCH, PROM1, PTCH1, PTCH2, RFX3, S1PR2, SGPP1, STAT5B, SULT2B1, TP63, VDR, VEGFA, VEZF1, WNT10B, WWTR1, YAP1"
GO:0009306,protein secretion,152,0.02,0.919,"AGT, ARFGAP3, C1QTNF5, CAMK2G, CARD11, CCL19, CHI3L1, CPLX1, CPLX3, DMTN, DYSF, ERP29, F2RL1, FFAR1, FOXP1, GNPTAB, GOLPH3, HNF1A, ILDR2, ITGAV, ITGB6, LMF1, MON1A, MYO5A, NECAB3, NOTCH1, PDX1, PTPRN2, RAB10, RAF1, S100A13, SMAD2, STEAP3, STX1A, SUCNR1, TANGO2, TANGO6, TCIRG1, TMEM106A, TRAF3IP2, UBE2Q1, VGF, ZBTB7B"
GO:0016569,covalent chromatin modification,346,0.02,0.92,"APBB1, ARID4B, ASXL1, ATXN7, BAP1, BAZ2A, BMI1, BRD1, CBX8, CREBBP, CTR9, DMAP1, DNMT3A, DOT1L, EHMT2, EP300, EP400, EZH2, GTF3C4, HDAC1, HDAC11, HDAC4, HDAC7, HDAC9, HLCS, HR, HSF4, JADE1, JADE2, JARID2, KANSL1, KAT6A, KAT7, KDM2B, KDM3A, KDM6B, KDM7A, KMT2C, LEF1, MAP3K7, MBD2, MBD3, MECOM, MIER1, MSL2, MTA1, MTA3, NACC2, NCOA1, NSD1, PADI3, PCGF3, PCGF5, PER2, PHF2, PPP5C, PRDM16, PRDM2, PRDM5, PRKCA, PRKCD, PRMT1, PRMT8, RBBP5, RING1, RTF1, RUVBL1, SATB1, SETD1A, SETD2, SIN3A, SIRT2, SMYD3, SUPT3H, TET2, TET3, USP22, USP3, USP36, USP7, WDR5"
GO:0032959,inositol trisphosphate biosynthetic process,16,0.02,0.354,"PLCB2, PLCB3, PLCB4, PLCE1, PLCH1, PLCH2, PLCL1, PLCL2, PTAFR"
GO:0010632,regulation of epithelial cell migration,264,0.02,0.968,"AAMP, ABL1, ACVRL1, AGT, ANGPT2, BCAR1, BCAS3, CAPN7, CARD10, CEACAM1, CLASP1, CORO1C, DAB2IP, DOCK1, DUSP10, ETS1, EVL, FBXW7, FGF1, FGF2, FGFR1, FOXP1, HDAC7, HDAC9, HMOX1, HYAL1, IQSEC1, ITGA2, ITGA3, JUP, MAP2K3, MAP2K5, MAPK14, MAPRE2, MARVELD3, MIR152, MIR200A, MMRN2, MTOR, NFE2L2, NOTCH1, PDCD6, PDGFB, PDPK1, PPARG, PRCP, PRKCA, PRKCE, PRKD2, PROX1, PTK2, PTPN23, PTPRG, RREB1, RTN4, SCARB1, SEMA3A, SH3BP1, SMOC2, SRC, STAT5A, TDGF1, TGFB1, THBS1, VEGFA"
GO:0001892,embryonic placenta development,87,0.02,0.976,"ARNT, BIRC6, BMP7, CASP8, CDKN1C, E2F8, EGFR, FGFR2, FZD5, GCM1, GRHL2, HEY1, HSF1, LEF1, MAP2K1, MAPK1, MDFI, NCOA1, OVOL2, PDGFB, PKD1, SETD2, SP3, ST14, STK3, TFEB, VASH2, WNT2"
GO:0110053,regulation of actin filament organization,245,0.02,0.934,"ABL1, ADD1, ADD2, ADD3, ALOX15, ARAP1, ARHGAP18, ARHGEF10L, ARPC1B, AVIL, BAIAP2, BAIAP2L2, BIN1, CAPG, CAPZB, CCL24, CDC42EP4, CDC42EP5, CFL1, CLASP1, DLC1, DMTN, EVL, F2RL1, FER, GSN, ICAM1, KANK1, LIMA1, LIMCH1, LPAR1, MLST8, MTOR, MYADM, MYO1C, NF2, PAK1, PHLDB2, PIK3R1, PPP1R9A, PREX1, PRKCD, PRKCE, PXN, RASA1, RICTOR, SH3BP1, SH3PXD2B, SMAD3, SORBS3, SPIRE1, SPIRE2, SPTAN1, SPTBN1, SPTBN2, SPTBN5, SYNPO, TRIOBP, TSC1, VILL, WASL, WDR1"
GO:0036293,response to decreased oxygen levels,337,0.03,0.987,"ABAT, ACTN4, ACVRL1, ADAM15, ADAM8, AK4, ALAD, ANG, ANGPT2, APOLD1, AQP1, ARNT, B3GAT1, BAD, BCL2, BMP2, BMP7, BNIP3, BRIP1, CA9, CACNB3, CAPN2, CARD16, CASP3, CBFA2T3, CFLAR, CPEB4, CREBBP, DNMT3A, DPP4, EEF2K, EIF4EBP1, EP300, ETS1, F7, FMN2, GNB1, HIF3A, HIPK2, HMOX1, HSD11B2, HSF1, HSP90B1, ICAM1, ITGA2, ITPR2, KCNK3, KCNMA1, LMNA, LONP1, MIR106B, MTHFR, MTOR, MYB, NDRG1, NFE2L2, NOTCH1, NPEPPS, OPA1, P4HB, PAK1, PAM, PDK1, PGF, PKLR, PLAT, PRKCE, PSMB10, PSMD11, PSMD3, RAF1, SCAP, SIRT2, SLC29A1, SMAD3, SMAD4, SRC, THBS1, TSC1, VEGFA, WTIP"
GO:0000165,MAPK cascade,342,0.03,0.932,"ADORA2B, AGT, BTRC, CALM1, CCL19, CCM2, CDC42EP5, CUL3, DAB2IP, EGFR, ERN2, FGF1, FGF19, FGF2, FGF9, FGFR1, FGFR2, FGFR3, FGFR4, FRS2, FYN, GRIN2B, HSF1, IKBKB, ITGAV, KITLG, KRAS, KSR1, LGALS9, MAP2K1, MAP2K3, MAP2K5, MAP2K6, MAP3K14, MAP3K5, MAP3K7, MAP3K9, MAP4K2, MAP4K3, MAP4K5, MAPK1, MAPK14, MAPK3, MAPK6, MAPK8IP3, MAPKAPK3, MBP, MEF2A, NLK, NOD1, NRAS, NRG1, PAK1, PAQR3, PDGFA, PDGFB, PEA15, PEBP1, PPP5C, PSMB10, PSMD11, PSMD3, PTK2, PTPN1, PTPRA, RAF1, RAPGEF2, RASA1, RASA2, RASA3, RASGRP1, ROR2, SHC3, SPTAN1, SPTBN1, SPTBN2, SPTBN5, SYNGAP1, TAB2, TAOK3, TGFB1, YWHAE"
GO:0006109,regulation of carbohydrate metabolic process,194,0.03,0.983,"AKT2, ARNT, BAD, CBFA2T3, DGKQ, DYRK2, ENTPD5, EP300, FOXK1, FOXK2, FOXO1, GNB3, GPD1, GSK3B, HDAC4, INSR, LCMT1, LEPR, MIDN, MLXIPL, MTOR, NCOA2, NUP188, NUP210, NUP93, NUP98, NUPL2, NUPR1, P2RY1, PASK, PDGFB, PDK1, PDK2, PDK4, PFKFB2, PFKFB4, PPP1CA, PRKCE, PTAFR, PTH1R, RAE1, RORC, SLC2A6, SLC45A3, SOGA1, SORBS1, SRC, TGFB1, WDR5, ZBTB20, ZBTB7A"
GO:0014031,mesenchymal cell development,75,0.03,0.879,"ALDH1A2, BCL2, BMPR1A, CFL1, CORO1C, EDN3, EDNRB, FOLR1, JAG1, KITLG, LAMA5, MAPK1, MAPK3, NOTCH1, NRG1, OVOL2, PDCD6, SEMA3A, SEMA3B, SEMA3C, SEMA3F, SEMA4B, SEMA4C, SEMA6A, SOX8"
GO:0048864,stem cell development,75,0.03,0.877,"ALDH1A2, BMPR1A, CFL1, CORO1C, EDN3, EDNRB, FOLR1, JAG1, KITLG, LAMA5, MAPK1, MAPK3, MSI2, NRG1, OVOL2, PDCD6, SEMA3A, SEMA3B, SEMA3C, SEMA3F, SEMA4B, SEMA4C, SEMA6A, SETD2, SOX8"
GO:0061326,renal tubule development,75,0.03,0.889,"ACAT1, AQP11, BCL2, BMP2, COL4A1, DLL1, FGF1, FGF2, HOXD11, IRX1, JAG1, KLHL3, LAMA5, LGR4, LGR5, MTSS1, NOTCH1, PBX1, PGF, PKD1, PTCH1, SMAD4, SOX8, TFAP2B, WNK4"
GO:0043502,regulation of muscle adaptation,96,0.03,0.994,"AGT, AKAP6, ATP2A2, CAMK2B, CAMK2D, CAMK2G, DDX39B, FOXO1, FOXO3, GATA5, GTF2IRD1, HDAC4, JARID2, LMNA, MEF2A, MIR25, MLIP, MTOR, NOTCH1, PAK1, PARP1, PDE9A, PI16, PPP3CA, PRKCA, PTK2, SGCA, SMAD3, SMAD4, UTRN"
GO:0042246,tissue regeneration,63,0.03,0.85,"ADAM15, CFLAR, DYSF, EYS, EZH2, GATA4, GSN, IGFBP1, LGR6, MUSTN1, NINJ1, NINJ2, NOTCH1, PAX7, PPP3CA, SGCA, SOX15, TEC, WNT10B, YAP1"
GO:0008015,blood circulation,377,0.03,0.989,"ABAT, ABR, ACE, ACTA2, ACVRL1, ADORA2B, ADRA1B, ADRB3, AGT, ATP1A1, ATP2B1, AVPR1B, BCR, BMP6, C9orf3, CACNA1D, CACNA1G, CACNB2, CAMK2D, CEACAM1, CHD7, CHGA, CHRM3, CORIN, CPS1, CSRP3, DDAH1, DLL1, DOCK4, E2F4, ECE1, EDN3, EDNRB, EGFR, ENPEP, EPHX2, F2R, F2RL1, GNB3, HMOX1, HSD11B2, ICAM1, ITGA1, KCND3, KCNE3, KCNH2, KCNJ2, KCNMA1, KCNQ1, KLK2, LRP5, MAP2K3, MAP2K6, MTOR, NAV2, NCALD, NEDD4L, NMU, NPR2, P2RX1, P2RY1, PDE3A, PDE4D, PDGFB, PER2, PIK3CA, PLCB3, PLOD3, PPARG, PPP1R13L, PRCP, PTAFR, PTPRO, RCAN1, REN, RNLS, SGK1, SLC2A5, SMAD3, SNX5, SRC, SUCNR1, TBC1D8, TBX20, TCAP, TGFB1, TNNI2, TRPM4, VEGFA, YES1"
GO:0008064,regulation of actin polymerization or depolymerization,167,0.03,0.919,"ADD1, ADD2, ADD3, ALOX15, ARHGAP18, ARPC1B, AVIL, BAIAP2, BAIAP2L2, BIN1, CAPG, CAPZB, CCL24, CDC42EP4, CDC42EP5, CFL1, DMTN, EVL, F2RL1, FER, GSN, ICAM1, KANK1, LIMA1, MLST8, MTOR, MYADM, MYO1C, PPP1R9A, PREX1, PRKCD, PRKCE, RASA1, RICTOR, SH3BP1, SPIRE1, SPIRE2, SPTAN1, SPTBN1, SPTBN2, SPTBN5, TRIOBP, VILL, WASL, WDR1"
GO:0016570,histone modification,338,0.03,0.922,"APBB1, ARID4B, ASXL1, ATXN7, BAP1, BAZ2A, BMI1, BRD1, CBX8, CREBBP, CTR9, DMAP1, DOT1L, EHMT2, EP300, EP400, EZH2, GTF3C4, HDAC1, HDAC11, HDAC4, HDAC7, HDAC9, HLCS, HR, HSF4, JADE1, JADE2, JARID2, KANSL1, KAT6A, KAT7, KDM2B, KDM3A, KDM6B, KDM7A, KMT2C, LEF1, MAP3K7, MBD3, MECOM, MIER1, MSL2, MTA1, MTA3, NACC2, NCOA1, NSD1, PADI3, PCGF3, PCGF5, PER2, PHF2, PPP5C, PRDM16, PRDM2, PRDM5, PRKCA, PRKCD, PRMT1, PRMT8, RBBP5, RING1, RTF1, RUVBL1, SATB1, SETD1A, SETD2, SIN3A, SIRT2, SMYD3, SUPT3H, TET2, TET3, USP22, USP3, USP36, USP7, WDR5"
GO:0003014,renal system process,105,0.03,0.994,"ADCY3, ADCY9, AGT, AKR1C3, AQP1, AQP2, BCL2, BCR, EDNRB, F2R, F2RL1, GNAI2, GSN, HNF1A, HSD11B2, ITGA3, KCNMA1, KCNQ1, KLHL3, MYO1E, MYO5B, PDGFB, PRKAR1B, PSAP, PTPRO, REN, SGK1, SLC9A3R1, SUCNR1, SULF2, TFAP2B, WNK4"
GO:0010634,positive regulation of epithelial cell migration,163,0.03,0.983,"AAMP, ABL1, AGT, BCAR1, BCAS3, CAPN7, CLASP1, DOCK1, ETS1, FGF1, FGF2, FGFR1, FOXP1, HDAC7, HDAC9, HMOX1, HYAL1, IQSEC1, ITGA2, ITGA3, MAP2K3, MAPK14, MAPRE2, MIR200A, MTOR, NFE2L2, PDCD6, PDGFB, PDPK1, PRKCA, PRKCE, PRKD2, PROX1, RREB1, RTN4, SCARB1, SMOC2, SRC, STAT5A, TDGF1, TGFB1, THBS1, VEGFA"
GO:0007431,salivary gland development,33,0.03,0.848,"BMP7, EDAR, EGFR, ESRP2, FGFR1, FGFR2, LAMA5, PAX6, PLXNA1, POLB, SEMA3A, SEMA3C, TFCP2L1, TGFB1"
GO:0150063,visual system development,339,0.03,0.927,"ACVRL1, ALDH1A2, ALDH1A3, ARID1A, ATF6, ATP2B1, BCL11B, BFSP1, BMP6, BMP7, CDK4, CDKN1C, CHD7, COL4A1, CRYBA1, DLL1, EGFR, EPHB2, FGF9, FOXP2, FRS2, FZD5, GNAT1, GNB1, GRHL2, HDAC1, HIPK2, HSF4, JAG1, KDM2B, LIMK2, LRP5, LRP5L, MAN2A1, MAX, MFN2, MFRP, MYH15, MYO7A, NF2, NINJ1, NIPBL, NKD1, NRL, OPA1, OSR2, PAX6, PDE6A, PDE6B, PDE6C, PPP1R13L, PRKCI, PROM1, PROX1, RAB11FIP4, RARA, RBP4, RING1, ROM1, RXRA, SDK2, SH3PXD2B, SIPA1L3, SLC25A25, SLC39A5, SMAD3, SMG9, SMOC1, SOX8, SP3, STRA6, TCIRG1, TFAP2B, THRB, TRAF3IP1, TSKU, TULP3, VEGFA, WNT2, WNT5B, ZNF513"
GO:2001235,positive regulation of apoptotic signaling pathway,177,0.03,0.963,"AGT, BAD, BBC3, BCL2, BMF, BNIP3, CASP8, CIDEB, CTNNA1, CYLD, DAB2IP, FBXW7, FLCN, G0S2, GSK3B, GSN, ITM2C, LGALS9, LTBR, MIR26B, NACC2, NMT1, NUPR1, PDIA3, PEA15, PLAGL2, PPP1CA, PPP1R13B, PPP2R1B, PPP3CC, PRKCD, PRR7, RAD9A, SIAH1, SLC9A3R1, SMAD3, ST18, STK3, TFAP4, TFDP2, THBS1, TNFSF12, TP63, TP73, TRAF2, WWOX, YWHAE"
GO:0097327,response to antineoplastic agent,93,0.03,0.991,"ABCC2, ADAM10, ADAM15, ADIRF, AQP1, CDH1, CDK4, CFLAR, CPS1, CTNNA1, DDI2, EGFR, EIF4EBP1, F7, FOXO1, GJB2, HMOX1, HSF1, ICAM1, JUP, KAT7, OPA1, PDGFB, PTAFR, RAP1A, SMYD3, SPIDR, STAR, TFAP4"
GO:0010611,regulation of cardiac muscle hypertrophy,64,0.03,0.886,"AGT, AKAP6, CAMK2D, DDX39B, FOXO1, GATA5, JARID2, LMNA, MEF2A, MIR25, MLIP, MTOR, NOTCH1, PAK1, PARP1, PDE9A, PI16, PPP3CA, PRKCA, PTK2, SMAD3, SMAD4"
GO:0010812,negative regulation of cell-substrate adhesion,64,0.03,0.861,"ACER2, ACTN4, ACVRL1, ADAM15, ANGPT2, BCAS3, CORO1C, DLC1, DMTN, FAM107A, HOXA7, JAG1, KANK1, NF2, NOTCH1, PHLDB2, PIK3R1, PTPRO, RASA1, RCC2, SRC, THBS1"
GO:0010506,regulation of autophagy,316,0.03,0.93,"ABL1, ABL2, ACER2, AMBRA1, ATG13, ATP6V0D1, ATP6V0E1, ATP6V1A, ATP6V1C2, BAD, BCL2, BMF, BNIP3, CALCOCO2, CASP3, CLEC16A, CTSA, DAP, DAPK1, DAPK2, EIF4G3, EP300, EXOC4, FBXL2, FBXW7, FEZ2, FLCN, FOXK1, FOXK2, FOXO1, FOXO3, FZD5, GATA4, GFAP, GSK3B, HMOX1, HTT, IL10RA, KEAP1, KIAA1324, LEPR, MAP3K7, MAPK3, MFN2, MLST8, MTMR9, MTOR, NOD1, NPRL3, NUPR1, PIK3CA, PIK3CB, PIK3R2, PSAP, PTK2, RAB1B, RPTOR, SESN1, SIRT2, SMURF1, SNX32, SNX5, SOGA1, SPTLC2, SREBF1, STK11, TAB2, TBC1D14, TFEB, TLK2, TPCN1, TRIM22, TSC1, USP10, USP30, USP36, VPS13D"
GO:0072659,protein localization to plasma membrane,178,0.03,0.913,"AKT2, AMN, ANK1, ANK3, ANXA2, ARHGAP44, ATP1B3, CACNB2, CACNB3, CDH1, DPP6, EFR3B, EHD2, FAM126A, GGA3, GOLPH3, GOLPH3L, GPR158, IKBKB, JUP, KCNIP3, LAMA5, MYADM, MYO5A, NFASC, NKD2, P2RY1, PACS2, PALM, PRKCZ, PTCH1, RAB10, RAB26, RAB40B, RAP1A, RAPGEF2, SKAP1, SLC9A3R1, SLMAP, SMURF1, SPTBN1, STXBP1, TESC, TMEM88, TTC7B, VAMP2"
GO:0001933,negative regulation of protein phosphorylation,395,0.03,0.949,"ABL1, AMBP, BMP7, CACTIN, CALM1, CASP3, CBLB, CDKN1C, CEACAM1, CHMP6, CHRNA10, CNKSR3, CORO1C, CRYBA1, CSK, CTDSP1, CTDSPL, CYLD, DAB2IP, DBNDD2, DGKQ, DMTN, DNAJA1, DTNBP1, DUSP10, DUSP16, DUSP2, DUSP8, EPHB2, F2RL1, FLCN, FOXO1, GNAQ, H2AFY, HIPK3, IGF1R, INPP5F, INPP5J, LDLRAD4, LRP5, MARVELD3, MECOM, MIR106B, MLLT1, MLXIPL, MTOR, MYADM, NDRG2, NF2, PAQR3, PARD3, PAX6, PDCD4, PDE4D, PDPK1, PEBP1, PIK3R2, PIP5KL1, PMEPA1, PPP1R1B, PPP5C, PRKAR1B, PRKCD, PRKCZ, PTPN1, PTPN6, QARS, RAPGEF1, RGS3, RPTOR, SEMA6A, SH2B3, SH3BP5, SIRT2, SLC9A3R1, SMAD4, SMAD6, SMAD7, SMYD3, SORL1, SPINK1, SPRED2, STK38, TAOK3, TESC, TFAP4, TGFB1, TNFAIP3, TRAF3IP1, UBASH3B, WNK2, WWTR1"
GO:1905114,cell surface receptor signaling pathway involved in cell-cell signaling,395,0.03,0.925,"AES, AGO2, AMOTL2, AP2A2, AXIN1, AXIN2, BCL9L, BMP2, BTRC, CALM1, CCDC88C, CDH3, CHRNA10, CHRNB1, CHRNE, CSNK1D, CSNK1E, CSNK2A1, CTR9, CUL3, CYLD, DAAM1, DVL2, FAM53B, FZD5, GLI2, GNB1, GRIN2B, GRIN2D, GRK5, GSK3B, HBP1, HIC1, HMGXB4, KREMEN1, LEF1, LGR4, LGR6, LRP4, LRP5, LRP5L, LRRFIP2, MAP3K7, MARK2, NDRG2, NFATC1, NKD1, NKD2, NLK, NOTUM, NXN, P2RX1, P2RX5, PDE6A, PDE6B, PDE6G, PKD1, PLCB2, PLCB3, PPP1CA, PPP1R9A, PPP3CA, PSMB10, PSMD11, PSMD3, PTK7, RECK, RNF138, ROR2, RTF1, SDC1, SLC29A1, SLC9A3R1, SMURF1, STK11, TCF7L2, TIAM1, TLE3, TMEM88, TNKS, TNRC6B, TNRC6C, TRABD2B, USP34, VANGL1, WNT10B, WNT2, WNT5B, WWOX, ZNRF3"
GO:0010921,regulation of phosphatase activity,169,0.03,0.734,"BMP2, CALM1, CD2BP2, CNST, CSRNP3, DMPK, ELFN2, ELL, ENSA, FARP1, FKBP1A, GNAI2, GPATCH2, GSK3B, HSP90B1, HTT, IKBKB, ITGA1, ITGA2, MTMR9, MTOR, MYO1D, NUAK1, PCIF1, PHACTR3, PPP1R12A, PPP1R14B, PPP1R16A, PPP1R16B, PPP1R1B, PPP1R36, PPP1R37, PPP1R9B, PPP2R1B, PPP2R5C, PPP2R5E, PPP4R2, RCAN1, SFI1, SH2D4A, SLC39A10, SLC7A14, SMAD3, TSC1, URI1"
GO:0007435,salivary gland morphogenesis,30,0.03,0.851,"BMP7, EDAR, EGFR, ESRP2, FGFR1, FGFR2, LAMA5, PAX6, PLXNA1, POLB, SEMA3A, SEMA3C, TGFB1"
GO:0040007,growth,376,0.03,0.972,"ABL1, ADAM15, ADD1, AGT, AKAP13, ANKRD11, ANXA2, ANXA6, APBA2, ARID2, ARID5B, AUTS2, BCL2, BMPR1A, CCM2, CDKN1C, CFLAR, COBL, CTR9, DLL1, DYSF, EP300, EYS, EZH2, FGF1, FGFR2, FGFR3, FLRT1, GATA4, GINS4, GLI2, GRHL2, GSN, HOXA5, IGFBP1, LEPR, LGR6, LRP4, MATN2, MESP1, MSX2, MTOR, MUSTN1, NIN, NINJ1, NINJ2, NIPBL, NOTCH1, PAX7, PDE4D, PLEKHA1, PLXNA1, PPP1R13L, PPP3CA, PRKCZ, PSAP, PTK7, RARA, RTF1, RXRA, SEMA3A, SEMA3F, SGCA, SHANK2, SLC12A5, SLC1A2, SLC25A25, SLIT1, SMAD2, SMAD3, SMAD4, SORBS2, SOX15, SPTBN2, SRC, STK11, STRA6, TEC, TIAM1, TMEM38B, WDR48, WNT10B, WWTR1, YAP1, ZMIZ1"
GO:0060391,positive regulation of SMAD protein signal transduction,11,0.03,0.698,"BMP6, BMPR1A, NUP93, PARP1, RBPMS, SMAD4, TGFB1"
GO:2001269,positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway,11,0.03,0.614,"CASP8, GSN, LGALS9, PRR7, SMAD3, ST18, TFAP4"
GO:0010990,regulation of SMAD protein complex assembly,6,0.03,0.343,"LDLRAD4, PARP1, PMEPA1, SMAD6, TBX20"
GO:0048589,developmental growth,372,0.04,0.971,"ABL1, ADAM15, ADD1, AGT, AKAP13, ANKRD11, ANXA2, ANXA6, APBA2, ARID2, ARID5B, AUTS2, BCL2, BMPR1A, CCM2, CDKN1C, CFLAR, COBL, CTR9, DLL1, DYSF, EP300, EYS, EZH2, FGF1, FGFR2, FGFR3, FLRT1, GATA4, GINS4, GLI2, GRHL2, GSN, HOXA5, IGFBP1, LEPR, LGR6, LRP4, MATN2, MESP1, MSX2, MTOR, MUSTN1, NIN, NINJ1, NINJ2, NIPBL, NOTCH1, PAX7, PDE4D, PLEKHA1, PLXNA1, PPP1R13L, PPP3CA, PRKCZ, PSAP, PTK7, RARA, RTF1, RXRA, SEMA3A, SEMA3F, SGCA, SHANK2, SLC12A5, SLC1A2, SLC25A25, SLIT1, SMAD2, SMAD3, SMAD4, SORBS2, SOX15, SPTBN2, STK11, STRA6, TEC, TIAM1, TMEM38B, WDR48, WNT10B, WWTR1, YAP1, ZMIZ1"
GO:0030952,establishment or maintenance of cytoskeleton polarity,17,0.04,0.309,"AQP1, CKAP5, LMNA, MAPKAP1, RHOBTB1, RHOBTB2, RHOF, RICTOR, RND2"
GO:0002433,immune response-regulating cell surface receptor signaling pathway involved in phagocytosis,69,0.04,0.838,"ABL1, ACTG1, ARPC1B, BAIAP2, DOCK1, FYN, MAPK1, MAPK3, MYO1C, PAK1, PIK3CA, PIK3CB, PIK3R1, PIK3R2, PRKCD, PRKCE, PTK2, SRC, VAV1, VAV2, WASL, YES1"
GO:0038096,Fc-gamma receptor signaling pathway involved in phagocytosis,69,0.04,0.838,"ABL1, ACTG1, ARPC1B, BAIAP2, DOCK1, FYN, MAPK1, MAPK3, MYO1C, PAK1, PIK3CA, PIK3CB, PIK3R1, PIK3R2, PRKCD, PRKCE, PTK2, SRC, VAV1, VAV2, WASL, YES1"
GO:0030010,establishment of cell polarity,116,0.04,0.965,"ALPK2, AMOTL2, BRSK1, CCL19, CFL1, CLASP1, CYTH1, FRMD4A, FRMD4B, FSCN1, GOLPH3, GSK3B, HTT, LLGL1, LLGL2, MARK2, MCPH1, NEK3, NUMA1, PAK1, PARD3, PAX6, PKD1, PRKCI, PRKCZ, PTK2, PTK7, RAB10, RICTOR, SH3BP1, SIPA1L3, SLC9A3R1, STK11, WWC1"
GO:0016540,protein autoprocessing,14,0.04,0.407,"AFG3L2, CASP1, FXN, MYRF, PARP1, PCSK9, PISD, TMPRSS2"
GO:0070293,renal absorption,14,0.04,0.644,"AKR1C3, GSN, HNF1A, KCNQ1, KLHL3, SGK1, SLC9A3R1, WNK4"
GO:0030858,positive regulation of epithelial cell differentiation,61,0.04,0.875,"ACVRL1, ADD1, BAD, BMP6, H2AFY, MESP1, NOTCH1, NUMA1, OVOL2, PAX6, PRKCH, PROM1, PTCH1, PTCH2, RFX3, S1PR2, SULT2B1, VDR, VEZF1, WNT10B"
GO:0007045,cell-substrate adherens junction assembly,27,0.04,0.659,"ACTN1, ARHGEF7, BCL2, BCR, DLC1, ITGA2, LAMA5, PDPK1, PEAK1, PTPRK, RCC2, SORBS1"
GO:0048041,focal adhesion assembly,27,0.04,0.659,"ACTN1, ARHGEF7, BCL2, BCR, DLC1, ITGA2, LAMA5, PDPK1, PEAK1, PTPRK, RCC2, SORBS1"
GO:0035051,cardiocyte differentiation,112,0.04,0.999,"AGT, AKAP13, ALPK2, ANXA2, ARID1A, BMP2, CSRP3, CXADR, FOLR1, GATA4, JAG1, KDM6B, LMNA, MAPK1, MAPK3, MEF2A, MESP1, MTOR, MYOM3, NEB, NOTCH1, NRG1, OBSL1, PDCD4, PROX1, RARA, RXRA, SMAD4, SORBS2, SOX6, TCAP, TSC1, VEGFA"
GO:0048562,embryonic organ morphogenesis,275,0.04,0.977,"ABR, ALDH1A3, ARID1A, ARL13B, BCR, BMP7, C2CD3, CCDC40, CHD7, CHRNA10, DLL1, DNAAF1, DVL2, EIF4A3, EPHB2, FGF9, FGFR1, FGFR2, FOLR1, FRS2, FZD5, GATA4, GLI2, GRHL2, HIPK2, HLX, HOXA2, HOXA3, HOXA4, HOXA5, HOXA6, HOXA7, HOXD10, HYAL1, KDM2B, LRIG3, MAPK1, MAPK3, MDFI, MESP1, MTHFD1, MYO15A, MYO7A, NDST1, NIPBL, NOTCH1, OSR2, OVOL2, PAX6, PROX1, PRRX1, PTK7, RBP4, ROR2, RUNX2, SETD2, SLC44A4, SLC9A3R1, SMAD2, SMAD3, SP3, STRA6, TBX20, TCAP, TRIOBP, TULP3, YAP1, ZIC1"
GO:0045444,fat cell differentiation,99,0.04,0.931,"AACS, AKT2, ARID5B, BNIP3, BSCL2, CTBP1, CTBP2, DYSF, EBF2, EP300, FAM120B, FFAR4, FOXO1, GRK5, LAMB3, METRNL, NIPBL, PER2, PIAS1, PPARG, PRDM16, SMAD6, SOX8, SREBF1, TCF7L2, TFAP2B, TRIM32, WNT5B, ZBTB7A, ZNF516"
GO:0007596,blood coagulation,280,0.04,0.924,"ACTG1, ACTN1, AKAP1, CAPZB, CD59, CLIC1, CSRP1, DGKE, DGKQ, DOCK1, DOCK9, DTNBP1, EHD1, EHD2, F2R, F2RL1, F7, FERMT3, FIBP, FYN, GATA4, GATA5, GNA11, GNA12, GNA14, GNAQ, GNB1, GP5, HDAC1, HMG20B, HNF4A, ITGA2, ITPR2, MAFK, MAPK1, MAPK3, MFN2, P2RX1, P2RX5, P2RY1, PAPSS2, PDPK1, PIK3CA, PIK3CB, PIK3R1, PLAT, PRCP, PRKAR1B, PRKCA, PRKCD, PRKCE, PRKCH, PROZ, PTPN6, RAB27A, RAD51B, RAF1, SERPIND1, SH2B1, SH2B3, SRC, STXBP1, TLN1, UBASH3B, VAV1, VAV2, ZFPM1"
GO:0018205,peptidyl-lysine modification,285,0.04,0.918,"APBB1, ARID4B, ATAT1, BCL11A, BRD1, CAMKMT, CREBBP, CTR9, DMAP1, DOT1L, EHMT2, EP300, EP400, ESCO1, EZH2, GTF3C4, HDAC4, HDAC9, JADE1, JADE2, KANSL1, KAT6A, KAT7, KDM3A, KMT2C, LEF1, LOXL4, MAP3K7, MBD3, MECOM, MSL2, NCOA1, NSD1, NSMCE2, NUP188, NUP210, NUP93, NUP98, NUPL2, PIAS1, PLOD3, POR, PRDM16, PRDM2, PRDM5, RAE1, RANGAP1, RBBP5, RTF1, RUVBL1, SAE1, SETD1A, SETD2, SETD4, SIRT2, SMYD3, STX1A, SUMO3, SUPT3H, TET2, TET3, TRPM4, USP22, WDR5, ZMIZ1, ZMIZ2"
GO:0003012,muscle system process,290,0.04,0.966,"ACTA2, ADORA2B, AGT, AKAP13, ARG2, ATP1A1, ATP2A2, CACNA1D, CACNA1G, CACNB2, CALM1, CAMK2D, CFLAR, CHGA, CHRM3, CHRNB1, CHRNE, CKMT2, CLCN1, CSRP3, DMPK, DYSF, EDN3, EDNRB, EZH2, GAMT, GATA4, GSN, GSTM2, HDAC4, HMOX1, INPP5F, ITGA1, ITGB5, KCND3, KCNE3, KCNH2, KCNJ12, KCNJ2, KCNMA1, KCNQ1, LTB4R, MAP2K3, MAP2K6, MTOR, MYL6, MYLK, MYOM3, NEB, NEDD4L, P2RY1, PDE4D, PIK3CA, PPP1R13L, PPP3CA, PXN, SGCA, SLMAP, SMTN, SORBS1, SORBS2, SORBS3, SSPN, SULF2, TBX20, TCAP, TIAM1, TLN1, TNNI2, TPM2, UTRN"
GO:1903053,regulation of extracellular matrix organization,38,0.04,0.842,"ABL1, ADTRP, AGT, CFLAR, CHADL, CLASP1, DPP4, ETS1, FGFR4, FSCN1, NOTCH1, PHLDB1, PHLDB2, SMAD3, TGFB1"
GO:0050808,synapse organization,266,0.04,0.935,"ACTG1, ACTN1, ADAM10, ADD2, AFG3L2, AGRN, ANK3, ARHGAP39, ARHGAP44, BAIAP2, BCAN, CACNB2, CACNB3, CAST, CDH1, CEL, CHRNB1, COL4A1, CTBP2, EFNB2, EPHA4, EPHB2, EPHB3, F2R, FARP1, FYN, FZD5, GNPAT, IGF1R, IGSF21, INSR, ITGA3, KLK8, LRP4, LRRC4, MYO5A, NDRG1, NFASC, NFIA, NLGN2, NRCAM, NRG1, PALM, PCDHGC3, PCDHGC4, PCDHGC5, PDZRN3, PLXNB2, PPP1R9A, PTPRD, PTPRF, RER1, SDK2, SHANK2, SPOCK2, SPTBN2, STAU1, SYBU, SYNGAP1, SYNPO, TANC1, TSC1, UTRN, WASL"
GO:0090596,sensory organ morphogenesis,242,0.04,0.964,"ABR, ALDH1A3, ARID1A, BCR, BMP7, CHD7, CHRNA10, DLL1, DVL2, EPHB2, FGF9, FGFR1, FGFR2, FRS2, FZD5, GLI2, GNAT1, HDAC1, HIPK2, HOXA2, JAG1, KDM2B, LRIG3, LRP5, MAN2A1, MAPK1, MAPK3, MFN2, MFRP, MYO15A, MYO7A, NIPBL, NKD1, NRL, OSR2, PAX6, PDE6C, PRKCI, PROM1, PROX1, PRRX1, PTK7, RBP4, RING1, ROM1, ROR2, SDK2, SLC44A4, SLC9A3R1, SOX8, SP3, STRA6, TCAP, TFAP2B, THRB, TRIOBP, TSKU, VEGFA, WNT2, ZIC1"
GO:0019216,regulation of lipid metabolic process,394,0.04,0.975,"ABCA2, ABHD6, AGT, AKR1C3, AKT2, AMBRA1, APPL2, ASAH1, ATP1A1, BCL11B, BMP2, BMP6, BSCL2, CAPN2, CCL19, CDK4, CEACAM1, CHD9, CHRM5, CISH, CPT1A, CREBBP, CREBL2, DAB2IP, DGKQ, ELOVL6, EPHA8, EPHX2, FABP3, FBXW7, FDPS, FGF1, FGF19, FGF2, FGFR3, FGFR4, G0S2, GNB3, GOLM1, H2AFY, HELZ2, HMGCS2, HNF4A, IDH1, KPNB1, LMF1, MBTPS1, MLXIPL, MTMR9, MTOR, NCOA1, NCOA2, NRBF2, OPA3, PDGFA, PDGFB, PDK1, PDK2, PDK4, PDPR, PIK3R1, PIK3R2, PIK3R3, POR, PPARG, PRKCD, PRKCE, PROX1, PSAP, PTK2, RGL1, RORC, RXRA, SCAP, SCARB1, SCT, SEC14L2, SIN3A, SLC45A3, SORBS1, SORL1, SRC, SREBF1, STAR, STAT5B, TGFB1, THRA, VAV2, VDR, ZBTB20, ZFP69"
GO:0045667,regulation of osteoblast differentiation,117,0.04,0.97,"ACVR2A, AXIN2, BMP2, BMP6, BMP7, BMPR1A, CDK6, CLIC1, ESRRA, FAM20C, FGFR2, HDAC4, HDAC7, HOXA2, ID3, IFITM1, IL6R, JAG1, LRP5, MSX2, NOTCH1, PDLIM7, PTCH1, PTK2, RUNX2, SMAD3, SMAD6, SMOC1, SUCO, TCIRG1, TP63, TRPM4, WNT10B, ZHX3"
GO:0046474,glycerophospholipid biosynthetic process,195,0.04,0.904,"ABHD3, ALOX15, CEPT1, CHKB, CHPT1, CSNK2A1, DGKQ, FAR1, FGF2, GNPAT, GPD1, INPP4A, INPP4B, INPP5F, INPP5J, INPPL1, LCAT, LPIN1, LPIN2, LPIN3, MPPE1, MTMR9, PEMT, PGAP2, PGAP3, PGS1, PI4KA, PIGQ, PIGU, PIK3CA, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PISD, PITPNM2, PLA2G2A, PLA2G4D, PLEKHA1, PLEKHA3, PLEKHA8, PNPLA3, RUFY1, SBF1, SH3YL1, SLC44A1, SLC44A3, SLC44A4, STARD10, STARD7, SYNJ1"
GO:0050679,positive regulation of epithelial cell proliferation,195,0.04,0.989,"ACVRL1, ANG, ARNT, BAD, BMP2, BMP6, BMPR1A, CAV2, CCL24, CDH13, CDH3, CFLAR, DYSF, EGFR, ESRP2, FGF1, FGF2, FGF9, FGFR1, FGFR2, FOXP2, HMOX1, HYAL1, MAP2K5, MTOR, NOTCH1, NRARP, NRAS, ODAM, OSR2, PDCD6, PDGFB, PDPK1, PGF, PPP1R16B, PRKCA, PRKD2, PROX1, RICTOR, RPTOR, RREB1, RTN4, STAT5A, TCF7L2, TNFAIP3, TNFSF12, TP63, VASH2, VEGFA, WDR48, WNT2"
GO:0038083,peptidyl-tyrosine autophosphorylation,31,0.04,0.679,"ABL1, EGFR, FER, FES, FYN, IGF1R, INSR, MAPK3, PTK2, SRC, TEC, TNK2, YES1"
GO:0003007,heart morphogenesis,238,0.04,0.999,"ACVRL1, ADAM15, ALDH1A2, ALPK2, ARID2, ARL13B, ASXL1, AXIN2, BMP2, BMP7, BMPR1A, C2CD3, CCDC40, CHD7, DLC1, DLL1, DNAAF1, DVL2, FGFR2, FGFRL1, FKBP1A, FOLR1, GATA4, GATA5, GRHL2, HEY1, INSR, JAG1, LEFTY1, MESP1, MSX2, MTOR, MYOM3, NIPBL, NOTCH1, NRG1, OVOL2, PDCD4, PPP1R13L, PROX1, PTCH1, PTK2, RARA, RBP4, RTN4, RXRA, SEMA3C, SMAD3, SMAD4, SMAD6, SMAD7, TBX20, TCAP, TGFB1, VEGFA, WNT2, YAP1, ZFPM1, ZMIZ1"
GO:1901861,regulation of muscle tissue development,149,0.04,0.998,"AKAP6, BCL2, BMP2, BMPR1A, DDX39B, DLL1, EFNB2, FAM129B, FBXO22, FGF2, FGF9, FGFR1, FGFR2, FLCN, FRS2, GPC1, HDAC4, HDAC9, JARID2, LEF1, MAPK1, MAPK14, MIR25, MTOR, NOTCH1, NRG1, PAK1, PI16, RBM24, RBP4, SIRT2, SMAD3, SMAD4, SOX15, SOX6, TBX20, TGFB1, TP73, WNT10B, WNT2, YAP1"
GO:0048010,vascular endothelial growth factor receptor signaling pathway,66,0.04,0.858,"BAIAP2, BCAR1, DAB2IP, DOCK1, FYN, ITGAV, MAPK14, MAPKAPK3, PDCD6, PGF, PIK3CA, PIK3CB, PIK3R1, PIK3R2, PRKD2, PTK2, PXN, SHB, SRC, VAV1, VAV2, VEGFA"
GO:0090257,regulation of muscle system process,243,0.04,0.995,"ABAT, ADORA2B, ADRA1B, AGT, AKAP6, ANXA6, ATP1A1, ATP2A2, ATP2B1, BIN1, CALM1, CAMK2B, CAMK2D, CAMK2G, CHGA, CHRM3, DDX39B, DMPK, DOCK4, F2R, FOXO1, FOXO3, GATA4, GATA5, GSTM2, GTF2IRD1, HDAC4, HSPB6, ITGA2, JARID2, JUP, KCNE3, KCNJ2, KCNMA1, KCNQ1, LMNA, MEF2A, MIR25, MLIP, MTOR, NMU, NOTCH1, P2RX1, PAK1, PARP1, PDE4D, PDE9A, PI16, PLCE1, PPP3CA, PRKCA, PTAFR, PTK2, SGCA, SMAD3, SMAD4, SMAD7, TMEM38B, TNNI2, TRPM4, UTRN"
GO:0090100,positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway,100,0.04,0.973,"ACVR1B, ACVR2A, ACVRL1, BMP2, BMP6, BMP7, BMPR1A, CDKN1C, CREBBP, EP300, FGF9, FLCN, GATA4, HIPK2, INHA, LEFTY1, MSX2, NOTCH1, NUMA1, NUP93, PARP1, RBPMS, RNF111, RNF165, SMAD2, SMAD4, STK11, TGFB1, THBS1, ZC3H3"
GO:0030178,negative regulation of Wnt signaling pathway,205,0.04,0.917,"AES, ALPK2, AXIN1, AXIN2, BICC1, BMP2, CUL3, CYLD, DAB2IP, DVL2, FGF9, FOXO1, GSK3B, HDAC1, HIC1, HMGXB4, IGFBP1, JADE1, KREMEN1, LRP4, MAD2L2, MAPK14, MDFI, MESP1, MLLT3, NFATC1, NKD1, NKD2, NLK, NOTCH1, NOTUM, NXN, PSMB10, PSMD11, PSMD3, PTPRO, RAPGEF1, ROR2, SIAH2, SLC9A3R1, STK11, STK3, TCF7L2, TLE3, TMEM88, TRABD2B, TSKU, UBAC2, WNT5B, WWOX, WWTR1, ZNRF3"
GO:0045747,positive regulation of Notch signaling pathway,50,0.04,0.81,"AAK1, BMP2K, CREBBP, DLL1, EP300, EPN2, GATA5, JAG1, JAG2, MAML2, MAML3, MESP1, NOTCH1, PRKCI, TP63, ZMIZ1"
GO:0001666,response to hypoxia,326,0.04,0.986,"ABAT, ACTN4, ACVRL1, ADAM15, ADAM8, AK4, ALAD, ANG, ANGPT2, APOLD1, AQP1, ARNT, B3GAT1, BAD, BCL2, BMP2, BMP7, BNIP3, BRIP1, CA9, CAPN2, CARD16, CASP3, CBFA2T3, CFLAR, CREBBP, DNMT3A, DPP4, EIF4EBP1, EP300, ETS1, F7, FMN2, GNB1, HIF3A, HIPK2, HMOX1, HSD11B2, HSF1, HSP90B1, ICAM1, ITGA2, ITPR2, KCNK3, KCNMA1, LMNA, LONP1, MIR106B, MTHFR, MTOR, MYB, NDRG1, NFE2L2, NOTCH1, NPEPPS, OPA1, P4HB, PAK1, PAM, PDK1, PGF, PKLR, PLAT, PRKCE, PSMB10, PSMD11, PSMD3, RAF1, SCAP, SIRT2, SLC29A1, SMAD3, SMAD4, SRC, THBS1, VEGFA, WTIP"
GO:0050817,coagulation,282,0.04,0.924,"ACTG1, ACTN1, AKAP1, CAPZB, CD59, CLIC1, CSRP1, DGKE, DGKQ, DOCK1, DOCK9, DTNBP1, EHD1, EHD2, F2R, F2RL1, F7, FERMT3, FIBP, FYN, GATA4, GATA5, GNA11, GNA12, GNA14, GNAQ, GNB1, GP5, HDAC1, HMG20B, HNF4A, ITGA2, ITPR2, MAFK, MAPK1, MAPK3, MFN2, P2RX1, P2RX5, P2RY1, PAPSS2, PDPK1, PIK3CA, PIK3CB, PIK3R1, PLAT, PRCP, PRKAR1B, PRKCA, PRKCD, PRKCE, PRKCH, PROZ, PTPN6, RAB27A, RAD51B, RAF1, SERPIND1, SH2B1, SH2B3, SRC, STXBP1, TLN1, UBASH3B, VAV1, VAV2, ZFPM1"
GO:0006650,glycerophospholipid metabolic process,287,0.04,0.906,"ABHD12, ABHD3, ABHD6, ALOX15, CEPT1, CHKB, CHPT1, CISH, CSNK2A1, DGKQ, EFR3B, FAM126A, FAR1, FGF2, GNPAT, GPD1, HRASLS2, IMPA2, INPP4A, INPP4B, INPP5F, INPP5J, INPPL1, LCAT, LIPC, LPCAT3, LPIN1, LPIN2, LPIN3, MBOAT1, MBOAT7, MPPE1, MTMR9, NAPEPLD, OSBPL10, OSBPL5, PEMT, PGAP2, PGAP3, PGS1, PI4KA, PIGQ, PIGU, PIK3CA, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PIP5KL1, PISD, PITPNM2, PLA2G2A, PLA2G4D, PLB1, PLCH2, PLEKHA1, PLEKHA3, PLEKHA8, PNPLA3, RUFY1, SBF1, SERINC5, SH3YL1, SLC44A1, SLC44A3, SLC44A4, STARD10, STARD7, SYNJ1, TTC7B"
GO:0090276,regulation of peptide hormone secretion,196,0.04,0.976,"AACS, ABAT, ANO1, BAD, CACNA1D, CHD7, CPT1A, DPP4, EGFR, ENSA, FFAR1, GHRHR, HNF4A, ILDR1, ITPR2, KCNS3, KIF5B, KISS1, KLF7, LRP5, LRP5L, MCU, MIDN, MYRIP, NLGN2, NMU, PASK, PDX1, PER2, PFKFB2, PHPT1, PPP3CA, PRKCA, PRKCE, RAP1A, RBP4, RFX3, RPH3AL, SCT, SLC2A2, SREBF1, STX1A, SYBU, TCF7L2, TCIRG1, TFAP2B, TIAM1, TM7SF3, TRPM4"
GO:0035270,endocrine system development,118,0.04,0.997,"ALDH1A2, ARID5B, BMP2, BMP6, BMPR1A, CDH1, CDK6, CDKN1C, DLL1, ETS1, FOXO1, GHRHR, GLI2, HNF4A, HOXA3, HOXA5, IL6R, INSR, MAP2K1, MAPK1, MAPK3, MNX1, NKX2-2, PAX6, PBX1, PDPK1, PDX1, RAF1, RFX3, SMAD2, SMAD3, STRA6, THRA, THRB"
GO:0048008,platelet-derived growth factor receptor signaling pathway,35,0.04,0.794,"ABL1, ARID5B, BCAR1, BCR, FER, MYO1E, PDGFA, PDGFB, PDGFRL, PLAT, PLEKHA1, PTPN1, RAPGEF1, VEGFA"
GO:0071526,semaphorin-plexin signaling pathway,35,0.04,0.703,"ARHGDIA, FARP2, PLXNA1, PLXNA2, PLXNB2, PLXNC1, SEMA3A, SEMA3B, SEMA3C, SEMA3F, SEMA4B, SEMA4C, SEMA6A, SH3BP1"
GO:0008217,regulation of blood pressure,173,0.04,0.988,"ABAT, ACE, ACTA2, ACVRL1, ADRA1B, ADRB3, AGT, ATP1A1, ATP2B1, AVPR1B, C9orf3, CHGA, CORIN, DDAH1, DLL1, ECE1, EDN3, EDNRB, ENPEP, EPHX2, F2R, F2RL1, GNB3, HMOX1, HSD11B2, KLK2, LRP5, NAV2, NCALD, NMU, NPR2, P2RX1, PDE4D, PDGFB, PLCB3, PPARG, PRCP, PTAFR, PTPRO, REN, RNLS, SGK1, SLC2A5, SMAD3, SNX5, SUCNR1"
GO:0034766,negative regulation of ion transmembrane transport,105,0.04,0.996,"AKT2, ANK3, ARL6IP5, BIN1, CAB39, CACNB3, CALM1, CAMK2D, COMMD1, DYSF, EPHB2, FKBP1A, GNB5, GOPC, GPR35, GSTM2, HECW2, KCNAB1, KCNE3, KCNH2, MTOR, NEDD4L, PCSK9, PRKCE, REM1, SESTD1, SLC9A3R1, THADA, THBS1, YWHAE"
GO:0010770,positive regulation of cell morphogenesis involved in differentiation,150,0.04,0.95,"ABL1, ANAPC2, ANKRD27, ARHGDIA, ARHGEF7, BAIAP2, CAMK2B, CRABP2, CUX1, DMTN, DOCK1, EEF2K, EPHA4, FBXO31, LRP8, MAP2K1, MAP6, METRN, MYADM, NEDD9, NIN, OBSL1, OLFM4, OPA1, PAK1, PARP6, PLXNA1, PLXNA2, PLXNB2, PLXNC1, PREX1, PTPRD, RAB21, RND2, RREB1, STK11, TIAM1, TRAK1, TRIOBP, VEGFA"
GO:0030833,regulation of actin filament polymerization,150,0.04,0.917,"ADD1, ADD2, ADD3, ALOX15, ARHGAP18, ARPC1B, AVIL, BAIAP2, BAIAP2L2, BIN1, CAPG, CAPZB, CCL24, CDC42EP4, CDC42EP5, DMTN, EVL, FER, GSN, ICAM1, KANK1, MLST8, MTOR, MYADM, MYO1C, PPP1R9A, PREX1, PRKCD, PRKCE, RASA1, RICTOR, SPIRE1, SPIRE2, SPTAN1, SPTBN1, SPTBN2, SPTBN5, TRIOBP, VILL, WASL"
GO:0046339,diacylglycerol metabolic process,21,0.04,0.461,"ANG, DAGLA, DAGLB, DGAT1, DGKE, DGKQ, LIPE, MOGAT2, PGS1, PLCE1"
GO:0003158,endothelium development,92,0.04,0.982,"ACVRL1, ANXA2, ARHGEF26, CCM2, COL18A1, DLL1, F2RL1, HEY1, ICAM1, JAG1, KDM6B, LAMA5, MESP1, MYADM, NOTCH1, NRG1, PDE4D, PLOD3, PPP1R16B, PRKD2, PROX1, RAB1B, RAP1A, RAPGEF1, RAPGEF2, SMAD4, VEZF1"
GO:0006644,phospholipid metabolic process,352,0.04,0.908,"ABHD12, ABHD3, ABHD6, ALOX15, CEPT1, CHKB, CHPT1, CISH, CSNK2A1, DGKE, DGKQ, DHDDS, DOLPP1, EFR3B, FAM126A, FAR1, FDPS, FGF2, GNPAT, GPD1, HMGCS2, HRASLS2, IMPA2, INPP4A, INPP4B, INPP5F, INPP5J, INPPL1, LCAT, LIPC, LPCAT3, LPIN1, LPIN2, LPIN3, MBOAT1, MBOAT7, MPPE1, MTMR9, NAPEPLD, OSBPL10, OSBPL5, PCSK9, PEMT, PGAP2, PGAP3, PGS1, PI4KA, PIGQ, PIGU, PIK3CA, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PIP5KL1, PISD, PITPNM2, PLA2G2A, PLA2G4D, PLB1, PLCB2, PLCH2, PLEKHA1, PLEKHA3, PLEKHA8, PNPLA3, RUFY1, SBF1, SERINC5, SGPP1, SH3YL1, SLC44A1, SLC44A3, SLC44A4, SMPDL3A, SPTLC2, STARD10, STARD7, SYNJ1, TMEM38B, TTC7B"
GO:0032872,regulation of stress-activated MAPK cascade,230,0.04,0.959,"AMBP, ARL6IP5, AXIN1, BMP2, CCL19, CYLD, DAB2IP, DNAJA1, DTNBP1, DUSP10, DVL2, EDAR, EGFR, EPHA4, ERN2, F2RL1, FGF19, FOXO1, FZD5, HIPK2, HIPK3, IGF1R, LGALS9, LTBR, MAP2K1, MAP3K5, MAP3K7, MAP3K9, MAP4K2, MAP4K5, MAPK1, MAPK3, MAPK8IP3, MARVELD3, MECOM, MFHAS1, NOD1, PAK1, PDCD4, PHLPP1, PRDX1, PRMT1, PTPN1, QARS, RAPGEF1, RASGRP1, ROR2, SEMA3A, SEMA4C, SH3RF1, STK3, TAOK3, TIAM1, TRAF2, VEGFA"
GO:0010001,glial cell differentiation,164,0.04,0.982,"ABCA2, ABL1, ADAM22, AKT2, BACE2, BNIP3, CDK6, CLU, CNTNAP1, CSK, DLL1, DTX1, DUSP10, EGFR, EIF2B5, GCM1, GPC1, GSN, HDAC11, KRAS, LEF1, LGI4, LPAR1, MAG, MAP2K1, MAPK1, MAPK3, METRN, MXRA8, MYRF, NDRG1, NKX2-2, NOTCH1, NRG1, PARD3, PAX6, PHGDH, PRDM8, ROR2, SH3TC2, SIRT2, SOX6, SOX8"
GO:0050775,positive regulation of dendrite morphogenesis,39,0.04,0.666,"ANAPC2, ANKRD27, BAIAP2, CAMK2B, CUX1, EEF2K, EPHA4, FBXO31, LRP8, OBSL1, OPA1, PARP6, PTPRD, RAB21, TIAM1"
GO:0046596,regulation of viral entry into host cell,28,0.04,0.463,"GSN, IFITM1, IFITM2, LGALS9, P4HB, TMPRSS2, TRIM11, TRIM25, TRIM26, TRIM5, TRIM62"
GO:0055075,potassium ion homeostasis,28,0.04,0.755,"ATP1A1, ATP1B3, KCNH2, KCNJ2, KCNMA1, KCTD7, SLC12A2, SLC12A4, SLC12A5, SLC12A7, SLC12A8, TFAP2B"
GO:0002431,Fc receptor mediated stimulatory signaling pathway,71,0.04,0.843,"ABL1, ACTG1, ARPC1B, BAIAP2, DOCK1, FYN, MAPK1, MAPK3, MYO1C, PAK1, PIK3CA, PIK3CB, PIK3R1, PIK3R2, PRKCD, PRKCE, PTK2, SRC, VAV1, VAV2, WASL, YES1"
GO:0014032,neural crest cell development,71,0.04,0.876,"ALDH1A2, BMPR1A, CFL1, CORO1C, EDN3, EDNRB, FOLR1, JAG1, KITLG, LAMA5, MAPK1, MAPK3, NRG1, OVOL2, PDCD6, SEMA3A, SEMA3B, SEMA3C, SEMA3F, SEMA4B, SEMA4C, SEMA6A, SOX8"
GO:0016202,regulation of striated muscle tissue development,146,0.05,0.998,"AKAP6, BCL2, BMP2, BMPR1A, DDX39B, DLL1, EFNB2, FAM129B, FBXO22, FGF2, FGF9, FGFR1, FGFR2, FRS2, GPC1, HDAC4, HDAC9, JARID2, LEF1, MAPK1, MAPK14, MIR25, MTOR, NOTCH1, NRG1, PAK1, PI16, RBM24, RBP4, SIRT2, SMAD3, SMAD4, SOX15, SOX6, TBX20, TGFB1, TP73, WNT10B, WNT2, YAP1"
GO:0034350,regulation of glial cell apoptotic process,9,0.05,0.659,"DLL1, PRKCA, PRKCD, PRKCH, PRKCI, TRAF2"
GO:0048845,venous blood vessel morphogenesis,9,0.04,0.628,"CCM2, EFNB2, NOTCH1, PROX1, TBX20, VEGFA"
GO:0031668,cellular response to extracellular stimulus,245,0.04,0.977,"ADORA2B, AES, AKR1C3, AMBRA1, AOC1, AQP2, ATP2B1, BAIAP2, BCL11A, BCL2, BRIP1, CACNB3, CBS, CLEC16A, COMT, CPEB4, CYP24A1, DAP, EHMT2, FAM107A, FBXO22, FES, FOLR1, FOXO1, FYN, GAS2L1, HMOX1, HSF1, HSP90B1, ICAM1, KIAA1324, MAP1LC3B2, MAP3K5, MAPK1, MAPK3, MAX, MTOR, NCOA1, NFE2L2, NPRL3, NUAK2, OPA1, P2RY1, PCSK9, PDK2, PDK4, PPARG, PPP1R9B, RPTOR, SESN1, SIPA1, SLC1A2, SLC38A3, SLC39A5, SREBF1, SZT2, TNKS, TRPM4, TSC1, UPP1, USF2, VDR"
GO:0014743,regulation of muscle hypertrophy,67,0.04,0.886,"AGT, AKAP6, CAMK2D, DDX39B, FOXO1, GATA5, JARID2, LMNA, MEF2A, MIR25, MLIP, MTOR, NOTCH1, PAK1, PARP1, PDE9A, PI16, PPP3CA, PRKCA, PTK2, SMAD3, SMAD4"
GO:0048706,embryonic skeletal system development,119,0.05,0.935,"ACVR2A, BMP7, EIF4A3, EXT1, FGF9, FGFR2, GRHL2, HOXA2, HOXA3, HOXA4, HOXA5, HOXA6, HOXA7, HOXD10, HYAL1, KIAA1217, MBTD1, MDFI, MTHFD1, NDST1, NIPBL, OSR2, PAX7, PBX1, PRRX1, RBP4, RUNX2, SETD2, SMAD2, SMAD3, SP3, SULF2, TULP3, XYLT1"
GO:0048738,cardiac muscle tissue development,160,0.05,0.996,"AGT, AKAP13, ALDH1A2, ALPK2, ARID1A, ARID2, BMP2, BMP7, BMPR1A, CHD7, CSRP3, CXADR, FGFR2, FKBP1A, GATA4, GATA5, KDM6B, LMNA, MEF2A, MESP1, MTOR, MYOM3, NEB, NOTCH1, NPRL3, NRG1, OBSL1, PPP1R13L, PROX1, RARA, RBP4, RXRA, SMAD4, SMAD7, SORBS2, SOX6, TBX20, TCAP, TGFB1, TSC1, VEGFA, WNT2, ZFPM1"
GO:0060324,face development,47,0.05,0.819,"ALDH1A2, ALDH1A3, ANKRD11, ARID5B, CHD7, CRISPLD2, EP300, GRHL2, LEF1, MAP2K1, MAPK1, MAPK3, NIPBL, PLEKHA1, RAF1, RARA, STRA6"
GO:0010766,negative regulation of sodium ion transport,18,0.05,0.731,"CAMK2D, COMMD1, HECW2, NEDD4L, PCSK9, PRKCE, SLC9A3R1, WNK2, WNK4"
GO:0046626,regulation of insulin receptor signaling pathway,59,0.05,0.846,"AGT, CCND3, CDK4, GNAI2, GRB14, GRB7, KANK1, MZB1, OPA1, PAK1, PIK3R1, PRKCD, PRKCZ, PTPN1, SORBS1, SORL1, SRC, TSC1, ZBTB7B"
GO:0090287,regulation of cellular response to growth factor stimulus,270,0.05,0.951,"ABL1, ACVRL1, AGT, ARNT, BCL9L, CAV2, CDKN1C, CFLAR, CREB3L1, CREBBP, DAB2IP, DLL1, EP300, EPN2, FAM129B, FAM20C, FGF1, FGF2, FGF9, FGFR1, FLCN, FOLR1, FSTL1, GATA4, GLG1, GPC1, HIPK2, ITGA3, LDLRAD4, LTBP1, MMRN2, MSX2, MYO1C, NOTCH1, NREP, NUMA1, PDCD6, PDPK1, PEG10, PMEPA1, PRDM16, PRKD2, PTPN1, RASL11B, RNF111, RNF165, RUNX2, SEMA6A, SKOR1, SMAD2, SMAD3, SMAD4, SMAD6, SMAD7, SMOC2, SMURF1, SORL1, STK11, SULF2, TFAP2B, TGFB1, THBS1, VEGFA, WFIKKN1, ZBTB7A"
GO:0014033,neural crest cell differentiation,80,0.05,0.879,"ALDH1A2, BMPR1A, CFL1, CORO1C, EDN3, EDNRB, FBXL17, FOLR1, JAG1, KITLG, LAMA5, MAPK1, MAPK3, NRG1, OVOL2, PDCD6, SEMA3A, SEMA3B, SEMA3C, SEMA3F, SEMA4B, SEMA4C, SEMA6A, SMAD4, SOX8"
GO:0007599,hemostasis,285,0.05,0.924,"ACTG1, ACTN1, AKAP1, CAPZB, CD59, CLIC1, CSRP1, DGKE, DGKQ, DOCK1, DOCK9, DTNBP1, EHD1, EHD2, F2R, F2RL1, F7, FERMT3, FIBP, FYN, GATA4, GATA5, GNA11, GNA12, GNA14, GNAQ, GNB1, GP5, HDAC1, HMG20B, HNF4A, ITGA2, ITPR2, MAFK, MAPK1, MAPK3, MFN2, P2RX1, P2RX5, P2RY1, PAPSS2, PDPK1, PIK3CA, PIK3CB, PIK3R1, PLAT, PRCP, PRKAR1B, PRKCA, PRKCD, PRKCE, PRKCH, PROZ, PTPN6, RAB27A, RAD51B, RAF1, SERPIND1, SH2B1, SH2B3, SRC, STXBP1, TLN1, UBASH3B, VAV1, VAV2, ZFPM1"
GO:1902017,regulation of cilium assembly,76,0.05,0.186,"CCDC88A, CDK10, CDKL1, CROCC, CYLD, HTT, KCTD17, MARK4, RABEP2, RABGAP1, SEPT9, SYNE2, TBC1D1, TBC1D10B, TBC1D14, TBC1D16, TBC1D2, TBC1D22A, TBC1D24, TBC1D2B, TBC1D5, TBC1D8, TCHP, WRAP73"
GO:0060841,venous blood vessel development,15,0.05,0.774,"ACVRL1, CCM2, EFNB2, NOTCH1, PROX1, SEMA3C, TBX20, VEGFA"
GO:0006069,ethanol oxidation,12,0.05,0.375,"ACSS1, ACSS2, ADH1C, ADH6, ALDH1A1, ALDH1B1, ALDH2"
GO:0010960,magnesium ion homeostasis,12,0.05,0.465,"ANK3, CNNM2, CNNM4, EDN3, EGFR, SLC41A1, TFAP2B"
GO:0033173,calcineurin-NFAT signaling cascade,12,0.05,0.361,"NFAT5, NFATC1, NFATC2, NFATC3, PPP3CA, PPP3CC, RCAN1"
GO:0032388,positive regulation of intracellular transport,208,0.05,0.979,"ADORA2B, AKT2, ANK3, ANP32B, ANXA2, ATG13, BAP1, BCAS3, CACNA1D, CACNB2, CACNB3, CDH1, CDH3, DMAP1, DYNC1H1, EHD1, EHD2, FBXW7, FYN, FZD5, GAB2, GSK3B, JUP, KIF5B, MAPK1, MAPK14, MYO1C, NPEPPS, NUMA1, PAK1, PCNT, PDZK1, PIK3R1, PIK3R2, PRKCD, PTPN23, RAB21, SAE1, SLC51B, SMAD3, SORL1, STX18, STXBP1, TCF7L2, TGFB1, UBE2D3, UBR5, USP36, VAMP2, YWHAE, ZIC1"
GO:0048596,embryonic camera-type eye morphogenesis,25,0.05,0.832,"ALDH1A3, ARID1A, BMP7, FRS2, FZD5, HIPK2, KDM2B, PAX6, PROX1, SP3, STRA6"
GO:0055083,monovalent inorganic anion homeostasis,25,0.05,0.713,"ABCC2, CA12, FGFR4, SLC12A2, SLC12A4, SLC12A5, SLC12A7, SLC12A8, SLC34A3, SLC9A3R1, TFAP2B"
GO:0038094,Fc-gamma receptor signaling pathway,72,0.05,0.84,"ABL1, ACTG1, ARPC1B, BAIAP2, DOCK1, FYN, MAPK1, MAPK3, MYO1C, PAK1, PIK3CA, PIK3CB, PIK3R1, PIK3R2, PRKCD, PRKCE, PTK2, SRC, VAV1, VAV2, WASL, YES1"
GO:0072080,nephron tubule development,72,0.05,0.888,"ACAT1, AQP11, BCL2, BMP2, DLL1, FGF1, FGF2, HOXD11, IRX1, JAG1, KLHL3, LAMA5, LGR4, MTSS1, NOTCH1, PBX1, PGF, PKD1, PTCH1, SMAD4, SOX8, TFAP2B, WNK4"
GO:0021915,neural tube development,152,0.05,0.985,"ABL1, ALDH1A2, AMBRA1, ARID1A, ARL13B, BMP7, C2CD3, CASP3, CFL1, COBL, DLC1, DVL2, FOLR1, GLI2, GRHL2, KDM2B, MTHFD1, MTHFR, NOTCH1, OVOL2, PAX6, PAX7, PHGDH, PKD1, PLOD3, PLXNA2, PLXNB2, PROX1, PTCH1, PTK7, RARA, SEMA3C, SEMA4C, SETD2, ST14, STK3, TGFB1, TRAF3IP1, TRIM71, TSC1, TULP3"