Supplementary Material 1. Concatenated ribosomal gene sequences alignment used for the phylogenomic tree. >GCA_016875485 ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????MRKLRIVARNSDKDKDKIEISHYILEKVPREAEVTRIEYEGPMLAVYTKKPEILV DQ----SSIV-----------AEIVGVIRKRIVV---RPDPSVRLPETEAEKMARELIAP EAEITDINFD--------PSLGEIIIETKKPGLVIGRNGTVLQEIIKKT-----KWRPHV LRS-----PPIKSKIVTHMRHYLHSESKERERILRTVGERIFRPKAYE--VGDIMLTVLG GAQEVGRSAFLIKTR-------ESSV--LLDCGINPGSQRPFEAFPRFDSPEFQIDQLDA VVITHAHLDHCGLTP----------FLYKYGYDGPVYCSAPTSNLMTMLQLDYLDVANKQ GVTPHYDQKDVRECVLHTIPLRFGVVTDI--APDIRL-TLHNSGHILGAAM--------- ----------AHLHIG-EGLH---N-IVYTSDYKFARTMLLEAAATEF-PRIETVITES- -----------------------TYGGHDDF----------------------------- ------MPSRVEAEESLTHVI----NETLERKGKVLIPVPA------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------IRAGKGKRRGRKMKQAIGPLIV-V-A-ENKG-------------- -----IFDAASNIPGVDVAMVYNLNAEMLAPGTNPGRLTLWTNGA---IEQLDK--LYGG GKGA-------------------------------------------------------- ---------------------------------------------MARGSS---YRVPLR RRREGKTDYKARRALV-LSGKPRLVARCSLKNVTAQIVVAKPYGDEVLASAHSRELKKKY GW----KAPTGNIPAAYLTGLLCGLKAKTK-GVEEAILDIGLIAPTRGAKVFATLSGVLD AGVDVPH--TEEKIVE------E-RTEGAHIAEYGKSLGP-GSEIYSAKFSKYLE--QKV SPEKLPEHFAKVKADI------------IGSF---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----KKGEKKA---????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????---------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------MPKEFMYRGHTLS--------------------SLQGMSMDEFIKLL PSRQRRSLQRGL------TPEQRILLEKMREAQEAV-KKGEDA--T-IKTH-VRDLI--- ------ILPEM----------------------------VGVKILVHNG--------KEF F-----------PVEIKPEMIGHY----------------------------LGE----- ----------FAVTN-KPVRHGT------------------------------------- -------------PGIGA-SR-------------------------------SSMYVPLK ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------KMNGPVPLPTKRLRVP VLKAPSGEGT-------ATWDRWEMRIHKRLIEI-DSEERVMRRIMRIRVPEEVHVTIEL I------MEKKE---------------------------------------EEPFSTKIF VVKT--TTGQERNVARLVSAKVEMTHIPIKAILVPDTLKGYVFIEADGPHFVEEAIVGVR HVRSRIPGLVSFSEIERYIIKKPV-LEDLDEDDVVEITGG--PFK--GMRAKITRIDKSK DEVTLELLEA-------TFTLP--------ITVHSDYVKLVEKAKT-------------- ---------KSG-EA--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------???????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????????????????????????-- ---------------------MGKRIRVQR-------------RGRGGSTFRASTHKRV- APAQYPLKITPKEAFEASISGV----IEALVHDPGRGAPLAFVHFENGET-CYTVTPEGI FKGQQINLGG-------------KAP---AEVGNILPLGKVPEGTLVCNLELRPGDGGKM AKSSGAYATVVGH-TP--Q-GTMIRLPSGRTRYINDYCMATIGVVSGGGRTEKPFLKAGE KFHLMKAKGHKYPRTRGRAMVAAVHPYG-SSK-RSA---R-K----GTTVSHGAPPGQKV GLIAARGPG-------QKKKRRVR------------------------------------ ----------MLKKW---------------EEQ----------------------PMLKP RIEKVVVNLNVGKSGEPLEKASKVLKEL-TNQ-APVKKKAK--K--TIRDFGIRKGESTA CVVTLRKQ-AA-IDFLKKVLPVVDNKISRAAFDRQGNFAFGIKEHIEIAGVKYDPDVGIF GMDVCVSVNRP-GHRVKTRRKEKTHIGHKHLLTPEESIAFVKQTLGVEI-V--------- --- >GCA_007126015 ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????----------------------------------------------------MVI E--------------------RKFVKDKLRESSI----------------KEYLSGFL-D RVGFSSVDIK------KTPVGFSVIIHASKPGLVVGRGGSNIKEIQKTLESKFGLESPVV DVR-EVERPELDSKIM----------AERIGSQLKRFGASKFKAIGHKELDNILKAGAIG AEIVVSGR-V------------PS-------------KRARTWRFY-------------- ----GGYLPKCGEVAKEEVIEGFYEVKLKPGIVG-------------------------- ----------IFVRIL---------------PPGV----------KMPDVV--------- ------------------------Y-L------------L-EE-DKIF-VE--E-IEEV- ---------------------------KEEK----------------------------- --------PEKEVK-----------EEKSEKEVK-------------------------- ---------------------------EEKPE---------------KEIKEEKPEKEI- KEEKTEKEIK------------------------------------KEK----------- -------KKKEKKKKEKSKEEVKEEKP--------------------------------- -----KEEVKEEKPEK-------------------------------------------- ------------------------------------------EEKEK------------- IEGE-------------------------------------------MSKVISVQGKAKE ELKLPFQFKE-LYRPDLIRRAALAIMSHQIKPEGVSEEAGKRQSSYFSKRRD-R---YRT TYGYGQSRTPRKVMSVKGSRFVTKGASVPQAVGGRKAHPAK-----VEKVSYEKINKKEK RKAIRSAISATAIKDVVESRGHKVE--NI-KDFPIIIEENIESIKKSKDVMELL---KKL GLEKELERTKE--KKVRAGKGKSRGRKYKRKTGPLFV-V-S-KKCD-------------- -----LINSAKNLPGVDVCKVKDLNLNLLAPGTNAGRLTIWSENS---IKLLEEKKLFE- ------------------------------------------------------------ -----------------------------------------??????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MLVEKLTFKGRTID--------------------EIKKMSLNEFMELL PSRKRRSLKRGF------TEQQKILLEKIRKAKKAL-EADKKV--GTIKTH-CRDMV--- ------ILPEM----------------------------LGLTIGVHNG--------KEF K-----------NVEITPEKMGHY----------------------------LGE----- ----------FTYNR-NRVQHSS------------------------------------- -------------PGVGA-TR-------------------------------GSTFVPVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MSKARIKLSSTDPEKINDIISQIEEIAKKTKVKYAGPIPFPTRGLKIP TRTSPDGEGR-------ELFETWEMRIHKRLIDL-DVDERALRLIMRIPVPREINVEIEI IE-----????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????????----------------MAKLRRASCYTKV--------------- -K-RPYTRKSRKR---EKSYVRGA-PYSKIVKFDLGNK----QADFPY-RVKLISKEDV- -QVRHNALEASRVSVNRIL-VRKAGKN-NYYFKIKTYPHHVLRENPIAA-GAGADRFQTG MSHSFGKPIGLAAQISK-GQEVMIVDV---D-KKYIDVAKTALKQAIYKC--PFKGRI-- ---------------------V-----ADKK----------------------------- -------------------------------------------????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????------------------------------------------------ ------------------MG----H-KINKPKYPKRGSRAFVPRVRAKRIYPKIKNW-P- K-TK-----ETKLLGFAAYKAGMTEITFVDNSANSLTK--GEMICVPVTILDAPKIKVAA IRFYKKD--ERR-FKK--VSTEIWTDKFDKE-----L-----KRKI-------------- ----SVP---KKK-----LNFEEE-----------------------IKKIN-------- ---IE--NSEDITVLVYTLP------KGRANRKKPEIFEIAIGGENIN---EKFEYAKSI LGN-EISVSDVLKEGEQVDVIAVTKGKGFQSPVKRNKIKLESK--KTDRTRRG--VAAI- GPDV-PRKVS-WTVPMPGQMGFHNRYDYNKWILKVGNE-------GLNFKKGLLNYGNVK EDYIILKGSIPGSSKRLIRFRFAVN---P-N-KGIP-EKTPEKINIDGVKK--------- ------------------------------------------------------------ ----MGKTKLDSIQEK-----------------------------------KKEKLEKKA K----EK--KEEELPLEE-EKKEKE--------------KPKKKVEVKK------P---- -KVNEAK----GRGEYLP-ISPKTSVEVCRAI--TGKPVEKAKKILNESINMERPIRFYR YKK-DTPHRK-----G---KGFGA-GRFPVKVSKYVLDVLENAIANAKYLEL-DPDELYV KLAIPNRAVSKESQ---------R--GRY----------TNLEIVV-------AKKVKKV ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------KK---------------------------------------- ---------------------MPKRLRQQR-------------AGKGTTTFRAPSFRYR- YKARY--KPLNEKEIHGKIDGK----IIDIFNDTARSAPLMLVEYQTGEQ-AILQAPYGI KVGDNVEAGV-------------DAE---IKKGNVVPVGSIPSGTLIYNIELVPGDGGKL VRAAGDSARVVAH-EK--D-KVVVMLPSKEMKRLNSKCRATIGSVAGFGRKEKPIIKAGR NYHIKKARGKYWPIVAGVAMNRVSHPHG-GKRRSTQ---HTK----KKPVGRRAPPGKKV GSIAAKRTG-------RKKR-----------------------------??????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??? >Bin497_genes ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????-----------------------------------------------------MI E--------------------RKFVAEKMKDFLV----------------RTYMSKSL-G SGKYSSISIK------KTPLGEKVVVYTAKPGLIVGKKGETIKGLTRALKSKFKMENPQI EVC-ELENPDLDAQTM----------AETIVNVLERFGPKRFKSTGYRTLQRIMDAGAMG AEINISGRGL------------PG-------------SRAKSWRFY-------------- ----AGYLKKSGDVSVSQVLYGMGVANLNSGSVG-------------------------- ----------IKVRIL---------------PPDA----------QLPDKI--------- ------------------------T-L------------K-DLSKAT--IQVEEIK---- ------------------------------------------------------------ --------E-EKVE-----------EKKPEV----------------------------- -------------------------------------------------------NKKVK KK---------------------------------------------------------- ------------VAKKKVKK---------------------------------------- -----KTVKKVT------------------------------------------------ ----------------------------------KD------EDKK-------------- ----------------------------------------------MKAEVKGMDGKKSK DVSLPRQFNE-EFRPDLIKKAVLSVQSHKRQPYGAFTRAGLGYSSYVSKRRK-E---YKS SYGHGNSRTPRKVMTRRGLHFFYVGATVPFTTGGRRAHPPK-----AEKDWNEKINITER RKAIRSAISATMDSKLVKKRGHTTE--S------IVIDSKIEDLKKSKEIYDLL---IKI -MPTEMKRVEY--KKVREGKGKHRGRKYKLKTGPLLV-V-S-KKCP-------------- -----LVQASMNLQGVDVCIVSDLNAELLAPGCDAGRLTVWTDGA---LERLEKENLFYK Q--------------------------------IKKKEIKK------------------- ---------------------------------------------MRRK-----KFVTYR RKREGKTNYAKRLRML-KGNQLRLVVRRSLKYITAQIVKYEKDGDKTLVSVSTKEL-KKR GW----KGYGNNIPAGYLVGLLIGKEAKKA-KIESAIFDIGLNN-TNSNVLFAILKGAVD SGLNVPH--SEDLYPK------QERIEGKHIS---------------------------- --DDVNKMFLTVKQNI-------------IEKVD-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAL-TCKVVKGLPVGAEIPTCDNSGA KVVKLIGVKG--HKTVRKRLAAAGIGDLISVSVIKGKQDMRKK---VVLAVVVRQRKEYR RPDGSRIKFEDNAVVVLKDDK-GNPKGTIFKGAIAKEATE-RWPGIAKVASIVV---MKE -------------------------KKNIG---IE-VDF-PKEK-----------C---- -E----DKHCPF------------------HGEIKVRGRMFNGIIIKKNPHKTVTVEWPR SFFIKKFERFAKRRSRIKAHNPKCMD--ANIGDKVMIAETRPISKTKNFVVVKI------ ----------EK------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFTFRGKNIG--------------------ELKSMDLKEFANLL PARQKRSLTRGF------SEPQKRLLARIQKAKDG-----KTK--KPVKTH-CRNMI--- ------VIPEM----------------------------VDTTVYIHSG--------KTF Q-----------QVLILPEMVGHY----------------------------LGE----- ----------LALTR-HRLKHSA------------------------------------- -------------PGIGA-TK-------------------------------SSAAASVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLSSTSIDKLNEITSSIQDIVGKTKVTLSGPIPLPTKKLKLT TRKSPDGEGK-------ASFDNFEMRIHKRLIDL-GVDERALRLVMRVPIPDNVNISIEL LD---------------------------------------------------------- -MKE---WSKD-----WISSKNPAKQRKYRYK-APLHIQQKF-MGVHLSPELRKKY---- ---------------------GRR-NITVRTGDSVIVLTG--QFK--KKTGKISEVKLKR GKVFVEGIEHVKKDGS-KALYA----------LNPTNLMITELILD-------------- ---------DKM-RK-----------------------------------KKLVKV---- ------------------------------------------------------------ --------EEKKNG---------------------------------------------- --------------------------------MVGLRPFSCYRTV--------------- -K-RAYTRKSKYR---SKGFIKAV-PVSKIVKFNFGNL----KKDFPK-TVNLLSKQRI- -QIRHNAIESARVTVVRHL-NKTIG-R-NYHFQIRIYPHHVLRENKMIT-GAGADRMQTG MQHAFGKAMGLAAQVKI-KQALFTVHV---D-KDDVEHARKALQSCAYKL--PCKCGI-- ---------------------E-----VI------------------------------- -------------------------------------------????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????------------------------------------------------ ---------------------------MPNKHHPRRGSMQFWPRARSRKHSATVYAW-A- D-SN-----ETKVLGFIGYKVGMTHLQLKEANPKSQRV--GMNVFTPATVIECPPVKVYS IRLFKGD--EDG-YK---IVSEIFSKKLDKE-----L-----NRKT-------------- ----RIA---K-----------KS-----------------------GEEVE-------- -------NFDRIRLTVYTQP-----KLTGIGKKKPDLIEVGIGGKDNK---EKLEYAKSL LDK-EVKLSDVFDEGEWVDVHGVTKGKGFAGCVKRYGVKRLQH--KSEKKIRG--IGTL- GAWT-TKKVQ-YTVPQPGKMGYHLRTEYNKLLMKLGV---KSE--EINPKGGFLQYGNVK NDYVLIKGSVPGARKRPITLVKAIR---P----KVK-APKV-EIVYTSLESKQ------- ------------------------------------------------------------ -----------------------------------------------------MVEEHKA S----------------------------------------------------------- -----------VFGSNLD-ISKKHSVVIGDFI--RGKDLDKAKNLMEEVIVKKTAVPFRR FNR-DMGHKK-----G----NIAA-GRYPVKAATRILGLLKSAESNAEDKGL-DVDA--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRLITQR-------------RGRGTTTYKSPSHRFK- GAIKYR-R-MDDMEKEGVTYGV----VKDLIDCPGHRAPLALVKYD-KEE-ILLSAALGI KVKDVVASGA-------------TAP---VQTGNTVPLHNIPEGTFVYNLEVRPGDGGKL VRSSGNFAKVMSK-TE--K-EVIVILPSRKQKKLDGRCRATIGIIAGGGAKEKPYLKAGT KMHAMRAKNNLYPKTSGVAMNAVDHPFG-SGRGRHA---G-K----PKTAPRWAPAGRNV GLIKAKRTG-------KRK----------------------------------------- -------------------------------MN----------------------KMKEI GVEKITLNIGTGKPGPELEKAKILLKAI-SGK-NPAETKTT--K--RIPGWSLRPGLTIG CKVTLRKN-DA-VKLIQRLLVAIDNQLSKRAFDKTGNFAFGVPEYLEVPEMEYIPEVGII GLEAAVTLERP-GYNIKKRSQKTKKIPQRHKISKEEAMAYAKEKLNVKI-KEEVEDEE-- --- >Bin407_genes ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????------------------------------------------------------- ------------------------------------------------------------ ------------------------------PGIVIGRKGADVEKLRLELRA-LTSKEIQL NVL-EVKVPELEASLV----------AENLAQQLKG--RVSFRRAMKRALQSTIRMGAEG IKITCKGR-L------------GGA------------EMARSETYK-------------- ----NGRIPL--HTLRADIDYALKVAYTTYGTIG-------------------------- ----------IKVWICKGEVLGKNEGVNNNTPPDK----------KQPRKR--------- ------------------------R----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????----MSDLKT----ALQKK RKRHQRRRLRGRKRLLGSSEKPRLIVYRSNNHIYAQLRDDMNEQTITGCSTLTPELLEKI ------KNATGNIEKAKIIGEYIAKLANDR-KIERVSFDRNGRR--YHGRIKALADGARS AGLKF------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------MIQEETKLIVADNTGA RRVKCFRILG----GTRRRY--ASLGDIIVVSVRSATPTSRVKKGSVSKAVVVRVKKEVR RKDGSYIRFDENACVLLDEK--MEMIGNRIFGPVARELREKKYMKIVSLAPEVL------ ---------------------------------MD------------------------- -N---------------------------QSGNRKVQ----HGVVTSAKSDKTISVKIER RLPHPRYKKYVTLSKKYLVHDPENT---CNVGDKVKIVECRPISRHKRWRLIEV------ ----------VE--------------------------------RTI------------- --------------------------------------?????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????????????????????????????????????????????------MA ------------GQTIRIKLKAYDHNLIDKSTEKIIRTARATGAAISGPIPLPTRRRVYT VLRSPHVDKK--------SREQFETRVHKRLIDILNSSSRTIDALMRLELPAGVDIEIKT ------------------------------------------------------------ -----------------------------------------------MIKRIKKIK---- ---------------------GNR--LFVRKGDQVLILTG--NDR--GRRGKVLKVYPEL NRIVVEGIAFMKRHTKPNQKAPQGGIVERERTINASNVMVIDPKIDQPTR--IGHKVLLV ---------DGR-KQRV---------------------------------RYSKKSGETL A----------------------------------------------------------- ------------------------------------------------------------ -------------G------------------ML-------------------SP----- -KRVPHRKVHRGRMR-GKAYRGST--------IAFG-------------KYGLKALEPG- -WITSRQIEASRIAITRHI--KRGGKV-----WIRIFPDKPITKKPAET------RMGKG K----GNPEFWVAVVKP-GRILFELEG--VD----EALARSAMSLATAKL--PILTRF-- ---------------------------VSRPD---------------------------- ------------------------------------------------------------ -----------------------------M-SMT-DPIADFITRIRNASRAGHVSVDI-P ESHIKRDIAKVLVRERFIEKYIRIRDDK-QGIIRIYLKYTPDG-------------KSVI DKINRISRPGLRLYYGVDKIPRV--------------------------LNGLGVLIITT PKGVMSDKQAREERVGGEPLCEVW------------------------------------ --MSRV----G-------REPIPIPDGVKLDIKNN-----LVEAS--GKLGEMQHELP-H G------ISAVV-NDGK-VEVS---RS-DES---RQQRSLHGLSRTLVANMLTGVSQG-F KRELEIVGVGYRCELK-----GKA--LQLTVGF----SHKVIFVPP-DGITFKVTSP--- ---TRFNVNGIDKQVVGDIAAKVRAVRPPEP--YKGKGI---------KYIDE-YIRRKA GKSTAS------------------------------------------------------ ------------------------------------------------------------ ------------MIGLLGRKKGMASVFVHD----------GKQIA--VTVLEVGPCPVVQ VKTTERD--KYNSIQ---------------------L----------------------- ------------------------------------------------------------ -------AFDPIRPKLVNRPASGHFESAGV-----------IPHRLLR---EFRDFEGEY KAG-DVLKADIFKDGDIVHVTGVSKGRGFAGVIKRHGFTRPNQSHGTHEAFRG--PGSI- GQASYPARVW-PGKRMPGRMGGARVTIKNLPVVKVD----------------------VE KSLIMVKGAVPGPPGSYISLRKAG------------------------------------ ---------------------------------------------------????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????????????????????????MP VIKRKPVTPSQRFMSVLDFSELTKKAPEKKLVKGLNRGGGRNNKGRVTVRFRGGGHKRR- ----Y--RIIDFKRNKPGIPAK----VAAIEYDPNRSANIALLHYVDGEK-RYIIAPNGL KVGAVIESGT-------------GLE---ISPGNMLPLMEIPPGTTVHNVEMKPGKGGQI ARGAGAGVQVMAK-DG--G-FVLLRLPSSEIRLFHENCMATIGQVGNIDHEKISIGKAGR KRWMGRR-----PHNRGVSMNPVDHPMG-GGEGKAS--GG-RH---PCTPWGKPTKGYKT ---RSRKKASDRLIVQRRRK-----------------------------??????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??? >GCA_003564925 ------M-RFKK--KKVVK-YRGSK--THGGGAMKKRR-GAGNRGGRGM-AGTGKRGDAK N---------PAINK--------------------------------------------- -----------------Y-NYFLISY----LNELNEL-YSIA-ED---------QIISIF NE--IEKKG--FENIIF--YGAGETARVL-L---------------KIYKNND--IIN-- ------------------------------------------------------------ ----------------------------------------------------------ME KK--------------NITVVNIVVSTSLEHDIP----------------LEKMAATL-S NTEYNPEQFPGLVIRIKEPKTSALIFSS---GNVVCTGARSIEKVRESIE---------- ----------------------------KIIKSLEKI-GIKIKIKPKINIQNIVASGSVG MDLNLNTLAMKLGNTEYEPEQFPGLVYKLDE------AKATFLLFS-------------- ----NGKVVCTGTKSEEQVHEAL------------------------------------- ------------------------------------------------DKL--------- --------------------------I--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --VNLKKVK--------------------------------------------------- ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????----MARKNK---RTITYR RRREGKTNYKRRLGLL-KSRKLRLIIRKFNKNIVIQLIEYHPEGDKTIASSHSREL-IKY GW----KYNKANIPASYLVGLLIGRKSKGK----EAIVDLGLQTPIKGGRLYAALKGAID GGLVINI--DKGIFPS------QDRIEGKHIIEYQK---------------------GKE NMKNFEKDFKQIKEKI------------TKV----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- ----------------------PRKQRKYIAK-APLHLKGKF-MNSNLSKDLRKKY---- ---------------------KIR-SVRVRKGDKVKIMRG--NFR--KKEGSVEKVDTKK CIVYISKIEIEKKEGS-KAPKP----------IKPSNIMIMELNLD-------------- ---------DKK-RR-----------------------------------EKIEAK---- ------------------------------------------------------------ -------IERKKNG---------------------------------------------- --------------------------------MAKLRRAVAYRRI--------------- -E-RPYTRKSKYR---KKTFIRAT-PTNKVIRYDLGDP----KKKYDY-TLNLMSKEAI- -QIRHNALESARLTSNRTL-EKQLGKT-GYHLKIKVYPHHVLRENPIAA-GAGADRFSTG MQKSFGKPIGLAAQIKE-NQTIFSLSV---N-KGSLKLAKEALRKAKNKF--PCSCIL-- ---------------------E------INKNN--------------------------- ------------------------------------------------------------ -----------------------------M-SLN-DPLGNVMSKINNYENIGKKKVQINN NSKLITEVLKVMKDNKYIGSYNEIQDDK-VNKIILNL----------------------L GNINKCGVIKPRYKVKKDEFEKFEK--------------------RFLPAKDFGILIVST SAGIITHKDAKEKSTGGKLIAFVY------------------------------------ -MKIDI------------DDILEIPEGVDVKLNDD-----IFEVS--GQKGTLKRMIK-N P-K----ITFDI-KENQ-IILS---AK-KST---KMGKKAINTYKAHLKNLFTGAKEG-Y IYKLKICASHFPMNVSVE---NNT--LI-IKNFIGEKTPRRLKLK--EGVSVKVDGS--- ----EILVEGVDKELVGQTAADIENLTKRPG---FDKRV----------FQDGIYIIEKA GKIIK------------------------------------------------------- ---------------------------MPNKRSPRKGSMQFWPRKRAKRPYARINSF-A- E-GK-----EPKLLGFAGYKAGMTHILVENNRKTSVTK--GEEIFCPVTVIECPPLKIYS VRFYKNK--Q--------LKTEVVNPNLNKE-----L-----TRKV-------------- ----IFS---K--------K-KSS-----------------------LDKIK-------- ---VE--DYDDIKISVYTQP-----KIIKM-KKKPEIFELGIGGSY-E---EKLKFVKEN IGK-DIPVESVFQEGQEVDIH--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????????????----------- --------------------------------------------------------MKEI KIEKVTLNFGAGKDSNQLKKGIKLLKNV-TSV-KPIETITN--K--RIPTWGIRPGLPIG CKVTLRKE-KA-VEILEKLLLAKEKKMNEKQFDENGNMAFGIAEYIDIPGIKYDPEIGII GFEVCVTLERA-GFRIKRRKIGKKKINKNHKITKEDAIDFMKNKFGVKI-GG-------- --- >GCA_016187335 -----MT-VRFE--KKVRK-MRGKR--WHGFGAKKKNR-GGGSRGGRGF-SGFHKHKFSY VTS-----KDPD--------------------------R-Y--G-------YK-GFAVPN KKKI------SA-----I-NLGDLER----IA------------------------AKNE ID--LNELG--YQKLL----SKGSVSRPL-KVIV---EKYTKKAGEKIRQAGG--SVE-- GEEVSK----------------------EKAKKKSEKRGQSGKK---------NQAKE-- ----------------------------------------------------------MK E--------------------RIFIQKAKENVGL----------------EEFIRGQF-K QAKCGKIEVQ------HTPIVTRIIIYTTTPGLVIGAGGERIRETTEQLRQKFSIENPQI DVQ-KIDNPDADPHIV----------AQNIANALET--GVNYKRLGNFYVEKIMEAGAVG CEIVFSGK-M------------SG-------------QRSRKERFT-------------- ----AGYLKKAGDPALKDVIKGFAVANPRLGNIG-------------------------- ----------VTVKIMI-------------RHADI----M-----QRAKKI--------- --------------------------I--------------------------------- ------------------------------------------------------------ --------ESKEAA-----------EEKAKEK---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------PEVAAAESPVAE------------------------------------ ---AARQ----------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------MPKLYDLSGKAVG EIELPQVFAT-AYRPDVIKRVVLSLQSKKRQRYGTDPLAGKRTSAHYHGRRK-Y-R--FA MMNKEMSRLPR-IHGKGAGYMAFRGRFSPQAVKGRRAHPPK-----AEKNWAQDVNKKEK LLALHSALSAAAMKDLVAARGHE----YA-GDVPLVIVDDFENVSKAKEARKIL---ASL GLEKELERCAE--KKVRAGRGKMRGRKYKRKKGPLLI-A-A-KKCA-------------- -----LLKAAANIPGVDAVSADELNAEHLAPGANAGRLVVMTKSA---LDNFSKKVLSK- ------------------------------------------------------------ --GKER---------------------------------------M--------FQMKFR RRAEQKTNYRKRLLML-LGRKNRIVVRRSSNGFSIQLVKYAEKGDQTFVEITSKHL-REH GW----KGHTGSMPAAYLTGMLFGKTAAKE-GFDSGIADLGLQS-KKSQSLFAAALGVRD AGIDIPV--DAEI----P----GERLKGKHIADYAQHLKSTDQEKYRKQFSACLK--SGL QPENITQHFEEVKKRI----------GEL------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKGL-TAKMTKPIQLKSRLNCADNTGA KELELISVKG--YKGRLRRLPKAGIGDVVICSVKKGKEKVRGT---VVYAVIVRQKKEYR RADGTRVKFMDNAAILVNPKT-FEPQGTEVRTVVAKEAVE-RFSPIGKISSIVL---MAR --------------------KKKTAVKNIG---IA-AEA-PKEA-----------C---- -G----SEKCPW------------------HGHLKVRGRVFSGKVVSSKALNTAIVEWNY YTYVPKYERYQRKNTRIAAHNPQCIA--AKEGDTVTIAECRPLSKAKRFVVVEK------ ----------VT-------------------------------------------A---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MAKKFTYHGLELE--------------------QLENMPLEEFAKLL PARHRRSLKRGL------SRKQKMLLEKIRRFR------GKDK--L-IRTH-ARDMV--- ------ILPEM----------------------------VGAKLGVHKG--------NEF V-----------TVSITEQMVGHY----------------------------LGE----- ----------FALTR-KRVQHSA------------------------------------- -------------PGLGA-TR-------------------------------SSKFVPLK ------------------------------------------------------------ ------------------------------------------------------------ ------------MNTARIKLTGKDPKQLDDLSKEIKDIAEKLGTAVSGPIPLPTKKLRVP VMRTPCGDGM-HRGGGGGNWETWEMRIHKRVLDV-GANDRVLRQITRIRIPRDVNIEIEL TD---------------------------------------------------------- ------MFSKQ-----WVSSSQPRKQRKYRYN-APLHLRHRM-LAAHLSRELRKEY---- ---------------------GKR-SLPVRKDDEVVVITG--SHK--GSKGKVSRVDMKE MKVYMENAKRKKVSGQ-EVQAP----------IDPSNVVITKLNLD-------------- ---------DSE-RK-----------------------------------KILERKKQ-- -----KGLTTKT----------------TEEMKP-------------------------E QSKEQKTKEEKK------------------------------------------------ --------------------------------MG-LRPGRCYRNL--------------- -Q-RPYTRQSIRVP--KKGYVKGV-PKPKIAEFQMG-T----VGDYDA-KLFLVSERDV- -QIRHNALESARIMVVQTL-DKKLGKGSTYFVRVRVYPHQVLRENAMAT-GAGADRFQSG MRDNFGKPVGTAARVMS-GQKIMEIQV---N-KNGIDTAKIALKKAGYKL--PTPTKI-- ---------------------L-----VEKKTGD-------------------------- ------------------------------------------------------------ -------------------------------MRH-DILVDVLYSVDNAEKSGKKSCVV-P ASDTVKNVLLVMQKAGYIGGFEFIDDGK-SGTFSVSL----------------------A GKINKSRAVRPRFAVKKNEYEKWET--------------------RFLPAKDFGMLIVST PRGVMSQKEAQKKGLGGRIVGYIY------------------------------------ -----MI-----------EKKIEVPEHVDVSVEGK-----KVVVK--GSKGSLERSFS-D P-RFVRTLVIEK-QGRE-IAVR---SS-KDT---KKHRAMVGTIEAHLKNMFLGVSSG-Y AYRMKIFYTHFPINITVK---DGE--VQ-IRNFLGEKGARTAKIV--GKAEVKLDKD--- ----EIVINGTDKEELGQTAANIEHACKISK---RDRRI----------FQDGVYLASRG VSE--------------------------------------------------------- ---------------------------MPTRRRPRRGSLQYWPRKRARRIYTRISHW-P- H-AK-----DVKPLGFAGYKAGMTHVQLIDNNNRSPTY--GKTISVPATILDAPSLFVLG YRLYKKS--SSG-LI---TASQKITDKIPKE-----L-------NI-------------- ----EKK---S----------RQS-----------------------SSD--E------- ---LK--EGDDVRLLVATQP-----GKSGMRKKKPEIFEIAV-GGDFS---KKKEYCESL LGK-ELSAADVMKSGEFVDVSAVTKGHGYMGPVKRFGIRIQTR--KDKQMHRH--VGSI- GSTV-PRHVD-WRVPAAGQYGLFTRTELNKRVLMIDG---DAG--KANATGGLLGYGVVP GTFILIEGSVPGSRKRLVRLRKAVR--------EQR-FIPA-EIKYISTESKQGK----- ------------------------------------------------------------ -------MPYTFL-------------------------------P----------KQPHA K----------------------------------------------------------- -----------AHGRNMR-ISRKSAVVLCAAI--RNKPLTRARRLLTDI----------- ----KSGRRS-LK------------GKYYSKTVDGILELLNSCEKNAGNLGL-DSERLFV -QAAAHQGTAMRRR------------RRKSGFGSHLKA-THLEIFLVERGKVNEEKTKEK ---MKKAVTEAVKKEVQKMKEKE-----------------KEISAAAAHEEKSAEES--- -----------EAEKKIKKD-----------FAAAERKGID------------------- -----------------------------EEIKEMKDKEREIEGR---ADEAK------- ------------------AKKRTN------------------------------------ ---------------------MGKNLIQQR-------------RGKGSPRYRSPGHRFI- GKVSY------QYLPKEARFGV----VKDIIDAPGKTTPVAVIDFSGQKF--LQIAHEGM FVGQPVSF----------------EE---AREGNILPLKKIPEGSKVYNIELIPGDGGRI CRSSGTFAMMISR-EE--N-KAIILLPSKEKKTLSADCRATMGSAASSGRIEKPFMKAGT KFYAMRTLNRLWPRTRGVAKNAVNHPFG-GQTR-----PG-K----VKSVSRHMPPGKKV GSISPRRMG-------KKKRKA-------------------------------------- --------------------------------------------------------MRRI RLEKVTLNIGCGT-KTSTETAKTILERV-TGT-TAVITKTH--K--R-STFGVAKNRPIG CKVTIR-K-GR-EEFLRRMLEAKENRLMKGSFDQTGNVSFGVKEYIDVPQMDYDPKIGVL GFDVCVTLERP-GYRVKKRKI-ASRIGKNHVIKKEEAVEFMKENFGVTI-EE-------- --- >Bin77_genes ----MKN---KR--KKSTR-HHGSH--THGRGAKKKAR-GSGHRGGFGM-AGTGKRADHK KSLILT-----------------------FKEK-----Y-F--G-------GS-SLNAK- -PRN---Y--EV-----I-N----VSD----LDKYSE-K--------------------E IE--LK-----GYKLL----GDGEVKKAF-TIKV---DFATKSAIKKVEGAGG--KVI-- LPEKKK--------------------EVEKVKKTEGKEEVEKNQ-------EGKEKTE-- ----------------------------------------------------------ME E--------------------RNFVKFKKEEFEM----------------KEFVKKYL-G MGKISRINVE------YTPVGEKIIITTSRPGLIIGRGGEKIEKLTQVLKRKYKFENVHL EIK-EIPEKNLDAQSV----------ADEIAVNIENLGSLRFKTIAYRLLKKIVDSGARG VELKLSGK-L------------PS-------------ARAKTWRFK-------------- ----KGYLKKVGDSS-KVVDKANAVAQTKSGTVG-------------------------- ----------IEVSIL---------------RPGV----------RIHDEI--------- ------------------------I-L------------H-PIVKVE--VKGES------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------ENGS------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MKSQLLSIDGKKVK EIELPKLFST-KIREDIMKKVFEA--EKQVQPYSPNPKAGRQHSASG-ISRKLR-HVWKS GYGHGRSRVPRKIMWRRGTQFYWIGAEISSTRGGRRAHPPKI--AHMLEK--KKINKKEL EIAMKSAIAGTAINDKVKGKYLRLADMEVKE-LPIVVESKLLGL-KTKELIKSL---ENI -LGKLFVVALPE-KRIRAGKGKLRNRKYKKSAGALLV-I-G-NKEDI------------- -----------KTKVIETQHVGNLMVSDLYP---TGRLVVYTEEA---INELGEAK---- ------------------------------------------------------------ --------------------------------------------------M---KKTAYK RKKQGKTDYKNRLGLL-KSGLARIVIRKTNKYIIVQYIKSKEARDKIIVGVSSKDL-LKN GWAKELEGSLKSVPASYLTGYLAGKKILEKSKDASAILDLGLQRNITGSRIYSALKGVID AGVKINC--DKKVFPS------EDRIAGKHLKE--------------------------- ---NVQKVIESVKEKIK------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAI-SARATRGLNIGSIVVAADNSGA RIVKIVSVKH--GKSSRKRQQYAKMADWVKVSVRKGKPEMKGE---VFDAVVVRLRRPYR RKTGERIAFSDNAVALLKDEK-GNPKGTQIKGAIAREVQE-RWGSVAKIARVVV------ ------------------------MEKKTEK---------REVE---------VATG--- ------KKL--VGA----------------RGKVAVRGRKFEGYVIR-KFDKRVTIRFER VNFIRKYERYSKSQTKIHAYLPEEFKDDIQIGDYIQVQECRPLSKIVHHVVVRK------ ----------IR-------------------------------------------SGEEK SI---------------------------------------------------------- ------------------MAIEQT------------------------------------ ------------------------------------------------------------ ----------VVKTRKEFTYRGKTIE--------------------ELKQLDIREFAKHL PSRERRTLLRNT-------DVIENFMSRCNKKLAKK---------KLIRTH-DRNII--- ------IIPKM----------------------------IDMIIFVYNG--------QNF E-----------KVIILPEMIGHR----------------------------LGE----- ----------FSLTR-KTVKHGA------------------------------------- -------------AGIGA-TR-------------------------------SSASRSVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MALVRIKLSSIDIKQLNEITDIIKDIANKSGTLASGPIPLPTKRLKIT TRKSPCGDGA-------ATFDNFEMRIHKRVIDL-PSNNRVLHSVMKLPIPKSVNIKIEM KD---------------------------------------------------------- -MKK--KFSTS-----WKSSKQTRKQRKYLAN-APLHLRRKI-MGANLSKELRKKY---- ---------------------GKR-SFPVRKEDEVKIMRG--KSK--GKTGKISVVESAK YRVAIEGIQRKKKDGT-KINMF----------FHCSNLQITKLNLD-------------- ---------DRK-RLKSLERGVNKKKIEVKTDVKPK--------------KTEEKVEE-- -----KK----------------------------------------------------- ------------------------------------------------------------ --------------------------------MASLRKAGAYSKK--------------- -YARPYTRVSKKR---TKNFIKTT-PMKKTVKFHMGNIKDYGKGKFDI-LVKVISKEQI- -QIRDNAIESTRQTITRHL-EKAIPGQ--FYFEIKIFPHHILRENKMLT-GAGSDRMQTG MQKSFGKAIGRAALVKP-GQMIFFVAT--SG-QKQLKAVKEALSSVKPKL--PCKIGV-- ---------------------V-----IEQVGK--------------------------- ------------------------------------------------------------ --------------------------------MSQDVIADTLNNVMNAKKAGKKVVVVKR FSKLLLNVLEIAKKLDYIEDYKTDGT-----DLEIEI----------------------G EGLNKCGAIKPRYTVAKEKLDRYLR--------------------RYLPAFNLGVVIVST NKGLMTHQEVLEKNIGGCLVAYFY------------------------------------ -MKLDI------------TEKVEIPEGIEVEISGA-----NVIVK--SGDKENKKKFN-F E-I----ISAKK-EGNE-IVLS---VK-KGT---KRERKMINTIRAHLNNMIKGVQEN-F VYELEIAFVHFPMTVEIDE-GKKE--IA-IKNFLGEKKPRICNII--DGAEVKIDGK--- ----IITVESYNKEIAGQMAANLEKETKVKK---KDVRK----------FQDGIYITSKC GKAI-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------MVDIRGVTKGKGFQGPVKRFGIALRQR--KSEKGIRK--VGSI- GPWH-PARVI-FRVPMAGQMGLFTRAVYNSKIIDIGS--ISEK--DINISGGFKKYGNVK TDYVVVYGSLQGPSKRALVLTHPLR---L-T-KKQS-KKSY-EVLELK------------ ----------------------------------------------------------MA D-EQLRQQQIPKQQKVVKPVEVAKAPV--KQEI--------------KTDVKAEDAEKKV E----EQ--KLEDIAEEHGSKPFEKVSKPGDEKKPGDEADEKK-VEKPKKKQ---PAKAV VRKYEAV----VHGKSLP-ISTKYAVAIAYFI--KNIRIDEAMENLEKVMKKQMAVPMKG ----ELAHRKGLRLDG---KKMMS-GKYPLKASKYFIKLLKTLNANATINGM-ELENTKI TEVIANKAPKQLHR---G--------GS-----MEHKR-THVMIKV-------KE---VK ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------K---------- ------------------------------------------------------------ ---------------------MGKRIISQA-------------RGHGSLTYRVRKKAFK- HRIKYP-Q---------KLEGQ--GEVIKLIHSAGHSAPLAKIKDEKQV--FFNLAHEKM YEGQK--VGA-------------DK----SIVGSILELKNIPAKTQIYNIESRPGDGGKF IRSAGSSAIVTKK-EK--G-KVKILMPSKKEKIFHENCRASIGVIAGKGRGDKPVVKAGK KYYIKKAKSKLWPRTSAVCMNAIDHPFG-SGRGKNL-----AHGKLGKIPRRNAPPGAKV GTIRPRKTG-------RGRGRK-------------------------------------- ----MVENEIKQEV-------------KEQSEN----------------------KMKVV EIEKVILS--CGGTKESLEKSVKLLKKI-SGK-KPSEKITK--R--RIPSFQIRPQMPVG CMVTLRGK-EA-LKLLARLLAAIDNQLKAKQIVDN-HFSFGIEEYINIPDEKYDREIGME GFKVTIVFSRK-GKRIARKKIKSGKIPKRQDVTKQEIIKFMEDNFKTEI-I--------- --- >GCA_003695265 ------M-RNKR--KKNTR-QRGSK--THGWGAMKKHR-GAGNRGGRGM-AGTGKKGDAK K---------PNIWK----------------SK-----Y-F--G-------KY-GF-K-- -KAK--KI--KA-----I-NLGDVEK----KLAAWEK-KGLA-AK---------EKDAYI ID--LGKLG--YEKLL----SKGSIKTKM-SISV---EKASKKAVEKVQKSGG--QVN-- V---------------------------LNASKDSGEE---------------------- ----------------------------------------------------------MI E--------------------RQFVAEKLKEFRI----------------QEFIRKNL-K GAGHSHTRLQ------RTPLGEKIIIYASRPGLVVGRRGENIKNLTEEIKNRFNLENPQI EIN-EVENINLDAQIV----------AERIANTLERFGAVRFKGIGHKTMVDVMNAGALG VEIIISGK-I------------PS-------------ARAKSWRFY-------------- ----SGYLKKCGDIALTGVRSAEAIAKLKTGVVG-------------------------- ----------IKVRIM---------------PPET----------TLPDRI--------- ------------------------K-T---------------KGKDE--VE--------- ---------------------------TEKK----------------------------- --------EEKEDK-----------EEGTEKK---------------------------- ---------------------------AEDKK---------------------TEEKSAE KKREKK------------------------------------------------------ -----------------TKKSSAK------------------------------------ -----KTTKKSS------EK---------------------------------------- --------------------------------------------KAD------------- KK--------------------------------------------MRIKVKTLEGAPEK EIELPKQFEE-EPRPDLVKKAVQVLQANKRQKYGASPEAGKRHSAELSRRRR-K---YRG SYGYGISRVPRKIMSRRGTRMNWEGAFAPGTRGGRRAHPPK-----AEKNWEQKINKKEN RKAIRSAISASVITEIVEKRGHKVP--K---DYPFVISSKIEDAEKTKEVKKVL---EKL GLKEELERVSK--TVRKEGKAKIRGRKTKVKIGPLIV-V-S-KECK-------------- -----LSKAAKNVKGVDVVPVNAINAEVLAPGAVMGRLTLWSESA---IEKMGKEKLYL- ------------------------------------------------------------ -------------------------------------------MQRRKSKR---YTVQYR RKREGKTNYKKRLKIV-MSGKDRLVIRKSSKHIWAQIIKYLPQGDKVLGSAHSREL-LKL GW----KASCSNVPAAYLTGLLLAQKIKHP---EELVVDIGIYTPVKKSRIYACLKGARD GGLKFKA--EEEIFPG------EDRIRGEHISKFASMKKQ------ESQFSK-VS--KLI DLTKIQTHFEEIKNKV----------KALKK----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAL-QSKMTNALPIGSIVPTCDNSGA KMIKIFAVLN--KKTVKGRKPSAGIGDLCMASVKKGKPEMRKQ---VVYAVIVRQKKEFR RSDGTRVKFEDNAAVVLKDDK-GNPKGTAFKGPIAKEACE-RWPGIAKLAGIIV----MK ----------------------------------------SKTK----------AK---- ------------------------------ERKIKTRGRTFVGTVISAKSAKTVTVEWSR VKKIAKYERLAKARTRVKAHNPPEIN--AKETDVVMIKECRPLSKTKKFIVVKV------ ----------LG-TDRDYLLEKAEEEIEQEKMKGKTTDKKEKMNAQLEKNTGVKKEAEKG EKTQST-----KQRNQKKSVKKAKLKGEN------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFRFYGKTLE--------------------ELKKMSITEFAQIL PARQKRSLLRGL------PDEHKKLLKKIEKKN-------------NVKTH-CRDMI--- ------VVPMM----------------------------LNKTIRIHNG--------KEF V-----------AVQIMPEMLGHY----------------------------LGE----- ----------FAMTR-KKVGHSA------------------------------------- -------------PGVGA-TR-------------------------------SSAAISVR ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARLKLASTEIDKINEVCKYIKDIVEKTGVEMRGPIPLPTKRLKIT TRKGPCGDGK-------ASWDRYEMRVHKRLIDL-GVDERTLRLVMRVPIPKGLNIEIEM IDV--------------------------------------------------------- -MKK--KWSKS-----WNKSKQPRKQRKYRYN-APLHVRDKF-MHATLSKELRKKY---- ---------------------GVR-SIRVRKGDKVIVMRG--QLK--GHSGKVERVDTKK HRIYVSKAEISKKDGS-KAQIP----------INCSNVMIQEL-VE-------------- ---------ERK-RFK----------------------------------RTQAKSQQ-- -----PKK---------------------------------------------------- --------EEKKEEKSEKQGQKSDASGKEDVK-----------AAKKDKKKANVVKND-- KKTP----------------------------MARLRKFSAYRNI--------------- -E-RPYTRKSKFK---NKSFVRAS-PNCRVVRFDMGNE----KAEFDT-TLELVSKDDI- -QIRHNAIESARQTSNRLL-DQKVGKT-NYKMKIMIYPHHILRENPLAS-GAGADRMSTG MKKSFGKPIGIAARVKK-GQTLIRLKV---N-KNNLDAARLALKRASHKM--PCSCNI-- ---------------------------------LTVSN---------------------- ------------------------------------------------------------ -----------------------------M-TLN-DPLANMFSSVLNCERIGKKECIVKP VSNMIKKVLDVMKEGMYIGDYKEIKNQR-GGELHINL----------------------L GNINKCGVIKPHYSVKKDGYEKYEK--------------------RFLPAKNFGILIVST TKGMMDHESAKKKSLGGKLIGYCY------------------------------------ -MREDQ------------KVVVEMPEGVSVELNNG-----LFKFK--GQKGEVEKKLA-N P-N----IISKV-EQNK-VVFE---VK-KGT---KREKKLLGTFKAHVRNAVKGVTEG-H VYKLKICSGHFPMNVSVS---GDE--FV-VKNFLGEKIPRKVKIS--NGVSVKVNGQ--- ----EVIVEGIDKQVVSQQAASIEQLCRITN---RDRRI----------FQDGIFIIEKD GKQVR------------------------------------------------------- ---------------------------MPKAHKPRSGSMQFWPRKRAKRSYPRLRNN-P- N-S------NPGLVGFAGYKAGMTHVIITDNRKTSTTK--GSDIICPITVIECPPIKIFS ARFYKNT--PSG-AA---LSSEIFSKNIDKN-----L-----AKKV-------------- ----KLP---K--------A-STK-----------------------KLDDVK------- -------EYDFIKAVVYTQP-----SLTGIGKKKPELFEIRIGGTK-E---EQLAFIKEY FDK-EVPIEKVFQEGEQVDVHSITKGKGTKGPVERFGIGLKEH--KSEKGVRN--PGSL- GPWRGQGHIL-YRVAHAGQHGYHQRTEYNKWLLKIGS---NPE--EINPKGGFINYGLVK NNYVLLKGSVSGPKKRLIILTKSSR---P-S-KKIP-KEAP-AIQHISLESKQGN----- ------------------------------------------------------------ ------MVDYSYK---------------------------------------EYN-ENMA R----------------------------------------------------------- -----------AIGRELA-ISTKASVEICNYI--RKRNLQEAKELLKLAKELKKPIPVRR FTE-GAGHKK-----G-----IGS-GKYYVKASSLILKLLESVEANALSKGL-NVNNLII KHICAHKASTPLRY------------GR--LRRRQMKR-THIEVVV-------EEKADKK ----SKASIKKEEKAEQKKEIK-------------------KEATQGKKESEKAE----- -----------EKKQESKAGAAEKEA-------IADEKD-----------AKS------- ----KKEAKDVK-REK---------------VPEPKNEEKK--------TDPK-PKKEEA ------------------EKEDPKK----------------------------------- ---------------------MGKRLIQQA-------------RGKGSPTYRAPSHRYV- GQVKY----PLLKDKK-VIKGE----IKDIIKCPGHESPLLVLKYDNGDY-GLNIAPEGV KTGDVIEIGA-------------TDK---ISAGNTMYLKDIPEGTSIFNIENLPGDGGKF VRSAGGFAKIISK-MK--N-EVLVQLPSKKRKKFKGDCKATIGIIAAGGRKEKPMLKAGK KYHAMKAKNKLYPRVSGASMNAVDHPFG-GSRSSRK---G-R----ATVAPKNAPPGRKV GMLRPKRVG-------RRKK---------------------------------------- -------------------------------MN----------------------PMKQI KIEKVTLNVGAGKDQNKLKKGMTLLKNI-TGI-SPVKTFTN--K--RIAAWGLRPGLPIG CKLTIRGK-KA-EELAKRLLEAKENSLKEEQFDDNGNVAFGIHEYIDIPQLEYDPNIGVM GLEVCITLQRP-GFRIKRRKIMKRKIPRNHRITKKEAIEFMKQKFNLKV--GEEE----- --- >GCA_004195435 -----MNDGKKR--KKVSR-HRGTH--THGRGAKKKAR-GSGHRGGVGK-AGTGKRADQK KLLQKN-------------------------KK-----Y-F--G-------K--RISGKP IKKN---I--EV-----I-NLNRFLED----FEKYEK-NGFV-KK---------NKDIYE VD--LK-----NFKII----GSADIKFKM-KISA---ISFTRGSKKSIEDAGG--EII-- --EKK------------------------------------------------------- ----------------------------------------------------------ME E--------------------RKFVKFKEEELGI----------------KEYIKENL-G KGKISEIKIE------YTPVGEKLIVSTNKPGIVIGRKGSKINELTEVLKKRFKLDNPHI EIN-EIIDIYLDAQLV----------ADTIAINLERRGSMKFKLIAYRMLKDIMNAGALG TELVLSGK-L------------PS-------------DRARTWRFT-------------- ----QGYLKKTGHPS-KQVKKAMSQEKTISGVVG-------------------------- ----------IKVSIL---------------TPDA----------ILEDRI--------- ------------------------D-I------------N-DKFKQK--IKENL------ ------------------------------------------------------------ ----------LEIE-----------K---------------------------------- --------------------------------------------------QTSNLTKKV- ------------------------------------------------------------ ----------------NKKK---------------------------------------- -----KGVEK-------------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MKSILYDIKGKKKS EIKLPGVFSS-KIREDIVRKYLET--ERIIQPYSNSPMAGKKHSASGTISHK-R-HDWKG HYGKGISRIPRKTMWRRGTQFMWIGAEISSTRGGRRAHPPK----GIGKE--KKINKKEI LIAMNSSFASTADKNHILNRYSSLEKINLPV--PFIIESKLEKM-KVKDILTSL---KNI -LGDLYPLVLKK-KSVRAGKGKLRGRKYKSNAGFLIV-T-G-KDEKL------------- -----------KISGLDIRSFDEISISDLYP---LGRFAIYTEKA---ILEMGGEKNAS- ------------------------------------------------------------ -----------------------------------------------MKKI---SRTVRR RRREAKTDYKSRLNLL-KSGLPRLVIRKTNKFVTGQIIESEIAQDKVIVSSSSRDL-LKK GWPEKNKGSLKSIPAAYLTGLMLGKKYGGGNK---LILDIGLHRNIKKSKIYAFLKGAF- ------L--LKRIY---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAI-GARATRSLNIGSKIIASDNSGA RIVKIVGVKR--GKASKGTQQYAKIGDHVKVSVRLGKPEMKGE---VFDAIVIRQKKPYR RKTGERVMFEDNAVALLKDDK-GNPKGTQIKGAVAREVSE-RWKAVGKIAQYIL---MSE -----------------------KMKMKEKK---------KEKK---------VM----- ------------------------------KSLVSTRGRIFQGEVIK-KFENRVVIEFTR TIYIPKYERFSKKKTKLHARIPEDLKVEV--GDYVKIRECRPLSKIVNFMVIET------ ----------IG-------------------------------------------GIEK- ------------------------------------------------------------ ------------------MVEE-------------------------------------- ------------------------------------------------------------ ----------IRKKIK--TFRGKELE--------------------FLKGLEIREVSEYL PSRSRRTLLRNF-------EEIDKFVKSCEAKSKKN---------SKIRTH-LRDMI--- ------IVPRL----------------------------VGMTIEVHNG--------RAF Q-----------HVQIIMEMIGHR----------------------------LGE----- ----------FAMTR-VRAKHTS------------------------------------- -------------AGFGA-TK-------------------------------GSRAKKK- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKVRIKLSSINIKELNNVIGMIKEITSRTGLLVRGPIPLPTKRLKIT TRKSPCGDGT-------ATFDRFEMRVHKRVLDL-PAEDRILHPIMMLKIPRSVQIKIEM KD---------------------------------------------------------- -MKQ--KFSTS-----WISSIQVRKQRKYRYN-APLHLRHKF-LSANLSKELRAKY---- ---------------------SKR-NVPLRKDDEVLVMRG--KFS--KKKGKILLVNLKT SKVKIVGLTRKKVDGT-EINVP----------FDPSNLQIIDLNLD-------------- ---------DKK-RL-----------------------------------KDIKREEK-- -----KIEERK------------------EEVRK-------------------------E LEKKNVSVKSESK----------------------------------------------- ---------------------------------MALRKAAAYTKK--------------- -KARPYTRKSKNR---SKSYIKVI-PQNKIVKYNLGNIQAYNDGKFKY-LVSFVADEKA- -QIRDNALESGRLVLNKNL-EKKVPKQ--FYIEIKVYPHHILRNNKTAA-GAGADRLSSG MKHSFGVVEGRAAMVNP-GKEIFFVAC--ET-EQVARIARDVMRILKSKM--PCKSKI-- ---------------------V-----M-NLNKK-------------------------- ------------------------------------------------------------ ---------------------MKN-----IVKMSQDIVADALNQIMNAKKAGKDSVKLKR HSKFLLSLLALGKLKGYISDYSLKEK-----NLKIKF----------------------S N-LNFCKAVKPRYVVKILNMDKYVK--------------------RYLPARDIGALIITT NQGLMTHQTALDKNLGGSLIAYFY------------------------------------ -MRKKI------------SFEIEIPEGVSCEYLDD-----VLECS--KGEAKVNRKIF-I P-K----TELKI-EESK-IILF---CE-KAN---RKNIAIMKTNLSHIKNIFKGLEEK-F IYELEICNVHFPMNCKLE---GKN--LI-IDNFLGEKIPRKAKIL--EDIDVSIQGN--- ----KITVSGNNIEKAGQTATNIEKATKFNN---RDRRI----------FQDGIFITSKP GGPI-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------KGNLLDVRGLTKGKGLSGPVKRFGITLKSH--KSEKGRRN--PGSI- GPWH-PAHVN-FRVPMSGQLGMFTRVHYNLKVLDSGN--ISEK--SFK-DFNFRKYGKLT GNYIILEGSVQGPSRRQILVTAPIR---P-S-KKQI-KKDH-EFLEMLK----------- -----------------------------------------------------MEEKKM- --EEKKMEE--KKEKH---KDNSKEKLIPKNELKENKGNEKDLKSDKKNEVKNKE-EAKQ T-------------------KNLDK----------------NK-LDSKKIK------KII TKKEEAI----AKSNNLP-ISKKHATYICNFI--KGKKIDESIFQLNEVLKFKRAIPFKG ----EIPHRK-----G---KGIMS-GRYPIKAVQNMINILKALKGNVIVNGM-DLEKIRI YIATSSWSSRPLRR------------GN-----RKSKR-TNVILKA-------KEFPEVK ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------K---------- ------------------------------------------------------------ ---------------------MGKRIIQQA-------------RGKGSFTYRVRRKAFN- KKVGYP-S---------G-SGE--AELLKLIHSAAHSAPIAKFKLEKEI--FFNVAFEGA FEGQRIAIGE-------------GN----SDTGNIILLKDISPSTKIFNIERNPGDGGKM IRSAGSKAVLHKKLEH--N-KIEILMPNKKIVKLNGNCRASIGIIAGDGRKKKPMLKAGR MFHKMKSRGKLWPRTSAVCMNAIDHPFG-SGRGKRI-----K----SKTAKRNSPPGRKV GHLSPRRTG-------KKK----------------------------------------- -------------------------------MN----------------------LMREP KVKKLILS--AGATGTNLDKSVKLFKIL-TGM-NPQIIKAGPKQ--RIPSFGVRPGLPLG TRVTIRGK-KS-IALLKKLLGAVDNSLNKKKVSEN-HLSFGIKEYVDIPGIEYDREIGIR GFNVTVNFERA-GKRVKIRKVKSGKLPKKQHISKEEIITKMEENFKTEF-R--------- --- >GCA_015121965 --------------MKSRK-LRGSS--TAGRGLGKRSRSGAGRRGGRGR-AGGGKR---- -------------------------------------------G-------QQ-NFASIK FYLK--ET--KTEKNMPL-NLSYLQS----HLDKLKR-KGII-QE---------KDGKLV VD--ITRGG-EYTKICGKFKGQGLKLSVY--------GKTSKQAKENILQNGG--EVN-- ----------------------------E------------------------------- ------------------------------------------------------------ -----------------------MINALMKEQVT----------------RDYLFKLF-S KFGISDIKLE------KTPLGERVVIRTPKPRAIINRASNELRIASKKLGEIFEQSPPRI EVE-ESEDPMLDPNVV----------ADALAFRVARFGPLKYKVIAHKMLDSIMSAGAIG AEIEMGGV-IK--------------------------ERAAHFKFRP------------- ---NGGILPKSGQIEDYGVRKGQKQLLLKRGVIG-------------------------- ----------IKVTIV-----------------------------TKSSKLGGI------ ------------------------N-I--------------------------------- ------------------------------------------------------------ -------------------------SDGRENR---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------GP GDGASKDEHKEDTGSAAS------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MKKAIVLSLSGQKAS EIELPDVFEY-RVDKELIKKAFLAEQSAKFQLKYTDPLAGKRKSSTLSKTRR-T---YKT VYGHGLTRTPKKVTWHVGTQFVYIGATAPNAVGGREAHPPQ-----QNKTLEKKINKKEK IAAIKSAISASANADIVKSF-HQIK--NF--ELPLIVEDKINDITKTKELYKVL---SSL GLDAETERAKR--KNIRAGKGKMRGRKYKRKLGMTII-T-T-EPTK-------------- -----LRKSAANL-NINVVDIKNLNIEDVSHAGKPGRLIVWSQGA---VSSLKL------ ------------------------------------------------------------ ---------------------------------------------MVKVNR--------- -----RTNYRARLGML-KSKLPRLVVRKTNSMIIGQIVEYEKSGDKTLSAVYSKEL-RAY GW----NFGLKNSPAAYLAGFLLGKKSSAK----EAILDKGSSTLKKDSFIYYFMKGASD AGIDVHT-KEFDI--------TEDRLFGKHIMEYASKGTTGN------QFSSVGK----- AINNMKDEFDTVLKKL----------NEYGK----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------M-KAAISKPINVGSYISVADNSGA KIAKVINVRG--YHGVKGRQPRCGVGDTIFIVVKKGNQDVIHK---TFPAVVIRQKKVFR RLNGLRLSFEDNACVLVKEIDKYEPLGTAIKGPIPREISI-RFPNVSKVAFKVV------ ----------------------------MQ---YDDLVK-PEVE-----------C---- -N----DKNCPY------------------HGTLKVHGSRFEGMVVSAKSKRTAVVQWIN FERLKKYDVYREKKTRVLAHNPDCIS--AKVNDRVVIYETRPLSRWKKFVIVRK------ ----------I------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------MEEFKFKSKSVE--------------------DLSKIPVDQLASVV NSSLRRRMKRGF------TDQQKKLIEKVEKAKKNG---------KPIKTH-LREMF--- ------ILPSF----------------------------VGITINVHNG--------KEF V-----------PVAIKPDMVFHR----------------------------LGE----- ----------FAITV-KQVRHGT------------------------------------- -------------PGLSA-TR-------------------------------SSSFVPIK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLTSTDTKQLKAVCDQIADISRKLGTSIKGPIPIPTKRIKVT TRRAPNGSGR-------ESYETWELRLHKRVIDM-QADPKALHLIMKTPIPKEVNIEMEI MGP--------------------------------------------------------- -MKD---FSKH-----WNGSKSPRKQRKYRAN-APLNLKHRM-VSAHLSKELRQQY---- ---------------------HTR-SFPIRKGDTVLVMRG--KFK--GSEGKVEKVYTKQ LRVTVDSAKITSKKGT-KIPIK----------IRPSALLIKELNLS-------------- ---------DKL-RE-----------------------------------KSLVKYGK-- -----AR----------------------------------------------------- ------------------------------------------------------------ --------------------------------MAKLRPGRAYRSM--------------- -K-QPYTRKSKFK---EKNYTKFA-LHTKITQFHSGNA----HNTFNK-RVEVISKSTL- -QVRDNALEAARIVANKYL-TDSIGEE-NFHIQLVSIPHHILREHKLAT-GAGADRFSAG MQKSFGKPIGLASQISA-GDKVFEIFV---N-EDHVNEAKEAADKIKKKLGFKTLALV-- ---------------------------I-------------------------------- ------------------------------------------------------------ --------------------------------MT-DQVSNALNVIFTSKISAKKECIITP MSNFILKILDIMSKGGYIDKYEVINDAR-GGFIKVTM----------------------N ENLNKCKSIRPRLPVKINEIQKYEE--------------------RFLPAIGFGMLIIST SKGLMTNAEVRQNGIGGNLIAYVY------------------------------------ -MSTKF------------STQL---DGADVKIENG-----EISVS--GPKGELKVKVV-Y S-----FLSVRK-EENT-LYIE---CK-KDT---DYQKAIAGTLAAQVRNMVKGVKEG-Y TAELELVYIHFPASMKLV---GDK--LV-VENFVGERKAREIFIP--KDVKTKVQGT--- ----KIILEGIDKYKVGQVAGTIEKNVQIKN---KDRRV----------FKDGIFIVKKP E----------------------------------------------------------- ------------------MG----H-QITKKSTPRRGSLQYYPIRKSKRPFHTLRAH-A- D-LE-----KDELSTFAGYKVGMRQAVYIDNDKNSPTF--KTELLSPVTILEVPPLLVVA ARLYKDN----------MSIGEVWAEA-DKN-----V-----GRRV-------------- ----------K-------FKPNNA----------------------NLEELLK------- -------KASDVKLLVSTTP-----WKINL-KKTPEIFEIELGGTL-E---QKAERAKSL LGK-EINASDSIKEGTFVDIGGVTKGKGFTGSVKRFGVKIYPV--HASKSRRK--AGNL- GAES-MAKVQ-FTVPQHGRLGFNSRTEFNKLVLKILN---DPA--EANIPQGYYRYGNLS APAIVLKGSVPGSTNRLLILRKAIR---P-N-KKLG----PTKVTLI------------- ------------------------------------------------------------ ----------------------------------------------------------MI K----QVS---------------------------------------------------- -----------AKSERVQ-VSLKHVHEIMESV--TGKNLDKAIKHLDGVLEEKRFIPFNK YG--GKGHKS-----GVP-------RGYPKRATKFVISLLKELKSNAKNINL-DEASIII KKYSLGRGKYPRFPSG-----AVYRHGKF----------TNLIVFG------EAEAKAPK ------------------------------------------------------------ ----------------------------------EEKKASV------------------- P----------------------------APAVEATNEKKE--------ENNNDATKEND ------------------KRTDEGAG---------------------NKGLPVQALQ--- ----------------------MKVPRSRR-------------RGK-SRIFRANTFKAI- ADTRI-------ISSNNAMNFK----VEDIIHDSYRTAPLMEIRFEDGTV-SYLPAFNGA YVGQILTFLK-------------GGD----RTGSIDSLKNIPTGANVYNVELRPNDGGKL VRSGGLSAKVIKK-EK--G-IVSIQLPSSRIIDINENCRAVVGVISNSGRMNKPLYKAGN NYHLKRARGRYWPLTAAVAMNAYEHKFG-GKRRSSQH----K----SKSVSRNAPPGAKV GTIAPRRTG------VK------------------------------------------- -------------------------------MNK-------------------DNKMRDI RIEKVTLNVGVGKAGAELDKIENLLKSI-AGA-QPFKTTSK--R--RIPEWGVRPGLEIG TAVTLRGK-AA-EEILGRLLEGIDKKLSKSKFDEGGNFSFGIPEYVHIPGVKYDYTVGIV GLSVAVTLSRP-GFSISRKRVR-RTVGKSHRIKKEEAINFISNKYNLQV-SD-------- --- >GCA_003649055 -----MT-VKRR--KKSRS-MRGVR--QHGFG--KTHR-GAGHRGGRGK-AGTGKKADQK K---------PNVW-----------------KT-----EYF--G-------KS-GFVRF- RTKK--SV--RV-----I-NLSTLED----KLDVFFD-KGFA-KK---------EGDFIA VD--LAKAG--YSRLL----GFGKIKHKF-KISV---ASASKAVVNKLEKAGC--TVV-- LNE--------------------------------------------------------- ----------------------------------------------------------MI E--------------------RKFIKENLKEFQI----------------KEYITNTL-K NVGHSETKLQ------RTPLGEKIVVSASRPGLVVGRKGENIKKLTNTLKNKFGLENPQI EIE-EVGNPNLDAQII----------AERIASTIERFGIQKFKGVGHKTLHDVMSAGALG VEIIMSGK-I------------PS-------------QRARSWRFY-------------- ----KGYLKKSGDVS-NYVLRAMSSANLKTGAIG-------------------------- ----------IKVSIM---------------HPTL----------KLPDDV--------- ------------------------S-V------------K-AEEAEN--IE--------- ------------------------------------------------------------ ---------------------NDLPEKKVEEN---------------------------- ---------------------------VEVKE---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------KVKK-------------- --------------------------------------------M-NEVKVLDLNNAEVG KLKLPSQFKE-DVRPDLIKRAFEAVMSNSRQPYGADPRAGKKYSARLTKRRR-K---YRG SYGKGISRVPRKILTRRGMQFNWVGAFAPGTVGGRRAFPPV-----AEKVWKVKINDKER RKAIRSALSASLNKEFASFRNHQVP--S---DFPFVVSDDFDKLSKTKDVISIL---NTL GFGDELKRSSR--KKIRPGKGKLRGRPYKKAKG-LLV-V-T-GNDKS------------- ----LVLKSAKNIPGIDVVFVKNLNAALLAPGGVPGRIALFTKGA---VELIDKEALFV- ------------------------------------------------------------ ---------------------------------------------MAKHKQ---GTVHFR RKREGKTNYKKRLQML-ISRKPRLVIRKSLNNIVIQLIEFHPEGDKILVAASSREL-IKM GW----KHNRGNLPASYLTGLLFGQKARQK-KVEDAILDMGLQTNVKGSRIYAALKGILD SGFNVPH--SEDIFPA------EERIKGTHI----------------------------- -SEALVKDFERLAAQL------------MKK----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAL-GTRVPKALPHYARIVACDNSGA RILKIISVKQ--SKTVKSRKPAAGVGDLIMASVVEGKPEMRKQ---VVMAVVVRQKKAIR RLDGLRVKFEDNAAVVIKDKF-GNPKGTMIKGPIAKEAAD-RWPLIGKVANTII------ ------------------------MRKV-------------------------------- -------------------------------KNISTHGRSFKGVIISDKMHNSATVEWTR KRLVPKYERLEKARTRVKAHN--SIG--AKKGDLVRVKECRPLSKTKHFIITEI------ ----------LS---------------------------------------------SKE AVEESR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MAKVLTYKGKTED--------------------ELKGMSIAEFAELT TARSRRTLQRGL------TDSQKIFLKRLQKATK------------PLKTH-CRDMV--- ------IVPEM----------------------------LGKKVLVHNG--------KDW N-----------PVEITVEMLGKR----------------------------LGE----- ----------FSLSR-KRVSHSA------------------------------------- -------------PGIGA-TR-------------------------------SSKHLSVR ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLASIDIHKLNQTCDFIKSISEKTGVEMRGPIPLPTKKLKIT TRKSPCGDGA-------ETFERFEMRVHKRLIDL-GLDERALRLVMRVPIPEGLNIEIEM IDV--------------------------------------------------------- -MKNQKKWNRS-----WKRSVQPRKQRAFVRN-APVNVRGNL-MGAHLSKELREKF---- ---------------------KFR-SVRIRKGDKVRVMLG--QFK--NKIGKVERVDTKR KKVYITGVEQSKLDGS-KALYP----------VHHSNVMIVELDLS-------------- ---------DKR-RFG-------------------------------------------- ------------------------------------------------------------ --------EVKK------------------------------------------------ ----------------???????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????----------------- -------------------------------MLN-DPLASVLSHIKNYEKLGKSECICKP VSKLITKVLSIMQEHGYIGSFEEIDDGK-GKVLKVNL----------------------L GKINDCGVIKPRFSVRLDTYEKVEK--------------------RFLIAKDFGFIVVST SQGMMTHKEAKEKNIGGKAIAYCY------------------------------------ -MKADI------------NLEAEIPEGVTVDITGN----GKISVK--GPKGKVFRQIK-D A-K----IKFQA-KDNK-VLLF---VK-GAT---KREKSLINTYFKHIQNMMKGVVEG-F VYKLKICSGHFPMNVAVS---GNK--LT-VKNFIGEKFPRVLTIK--DAVDVKVDGD--- ----IITVESIDKEKAGQVAADIENMMRVTN---RDRRI----------FQDGIYIIEKA GKTI-------------------------------------------------------- ---------------------------MPKKHNPRRSSLQFRPRKRARSENVRVRTW-P- KKIS-----ESKLLGFAGYKVGMTHVIVSDTSHLKERK--GKPLFLPVTVVECPPMKVLG FRGYINT--HYG-LR---CKAQRWVDNLDKID--KNL-----SRSL-------------- ----SFP------------KKSKN-----------------------ASEIPGE------ -------NLDEVRLLVMTQP-----GKTGIGKKKPEIFEVGLGGEV-A---EQLKFAEDY LGK-EIRVGDVLKESQQIDTCSVTKG---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----MVAYKYST-----------------------------------------ELKENMA K----------------------------------------------------------- -----------AVGLALP-ISSKVSREVCAKI--RGMKLDKAKTLLEDVIALKAAIPYRR YTG-DVPHQA-----G-----VGP-GRYPVKASMHILKILKAAEANAQFKGL-SINNLFI KHVSAQKGSKTIRY------------GR--RHN-IAKR-TNIEVVL-------EEKK--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRIIQQA-------------RGKGGPRYRSPGFKFL- GDIKYR---SLDFMGV---KGV----VRDFAKCPGHLSPLAAVEFEDGFR-AFMIAPEGI RTGEVISFG--------------GDE---IKSGNVLFLKDIPEGTEVFNIESSPGDGGKF CRTSGMNAKIVSK-TD--K-NVVVLLPSKKKRVFSLKCRATIGIVSGGGRHEKPFLKAGN KFYARKARNKLYPLTHASAMNAVDHPFG-NKRTSRK---A-K----QKGASKLAPPGRKV GKLWPKRTG-------KRN----------------------------------------- -------------------------------MN----------------------PMQKT RLAKVTLNIGAGKDQAKLEKGIQLIKAI-TGI-EPVKTITQ--K--RIPSWGVRPGLPIG CKLTLRKE-KA-KEVLKRLFVAKDNVLKLNNVDSFGNVSFGIEEYIDIPGVPYDPKIGVL GLQVCITLEKP-GFRIKHRKVRAKKIPKKHSVKKVDAVNFLKDEFNVKI-EGERT----- --- >GCA_016432325 -----MV-VRRE--RAVRK-KRGSK--WHGWGGKKKHR-GAGSRGGHGF-AGSISHNLIW ASR-----VAPD--------------------------R-M--G-------KH-GFSRPQ KVLT--FS--RA-----A-NVGDIER----LA-----------------------KGSKD VD--LNALG--FGKLL----SKGFITKPV-KVTV---KACSPGAKEKIEKAGG--SV--- ---------------------------------------ITG------------------ --------------------------------------------------------MASI K--------------------KTFVNKGIRKLTI----------------EEYLRNSF-Q KAGYSHSDIR------RTPLGMQITVHADRVGLIIGRGGQTINAMTEKLEKDYGLENPRL NVE-EIGKPFLNAKIV----------AEEIKNAVEK--KVNHRKICNIMMQRILAAGAVG CQIRISGR-I------------GG-------------AKSRRDKFN-------------- ----IGYLKHSGQYAKDLVDTATVEAQTKLSSIG-------------------------- ----------IKVKIMR-------------SKPEADIASLRAIMEKRPEAA--------- ------------QAVQLRCPVCSKDYD-------------NERSL--K-IHIGQRH---- ------------------------------------------------------------ ----------PEAQ-----------APVASA----------------------------- ----------------------------------------------------QADASPP- -QEDT--------------------------------KVAQLLE---------------- --------GNVSDVRKKIEDARRPDVKLL------------------------------- ----LRSEKEGKNRKGV--------------------VEYLERR---------------- --------------------------------VAEK------EAKS-------------- -----------------------------------------------MADVHGLDGKKTG TIELPKVFQT-PYRPDLIARAVLAYQSARRQAYGTDPKAGMRSSAHYHGYRK-F-RPEVV MMNREMARLPR-IHGDAPAHLGMRARLVSGAVGGRTVHGPR-----SARIWTQKLNVRER IAAIRSAIAATTRADLVAARRHA----YT-GSVPLVVADDIQNVKKTKELVKTL---LAL GLEKEIERTSE--KRVRAGRGKMRGRRYKVRKGPLLV-V-S-KDGG-------------- -----IVKAAAGVLGMDVAHVRGLNAELLAPGTQSGRLTIWSKSA---VEEIGKKYA--- ------------------------------------------------------------ ---------------------------------------------MARSAI---HIVQHR RRREQKTDYQLRLSLL-RSGMPRVVVRKSNLYVRGQIINYETAGDRVVAQADSAEL-KAM GW----KHSCANVAASYLTGLLLG---KRA-GVKDAIFDIGLQRSTKGNVLYAFLKGVVD AGVAVPH--NPEIMPP------ADRLNGKHI-----KAEAE------------------- --------FETVKKKI------------LG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MRPV-SARIIKGINHSAWLDCADNSGA KILRVFTVKG--YKGTKRRMVKCGVGDVIMCSVKRGTPKMREE---TPLAVVIRQRKEYR RYDGRRIKFEDNAAVLVNDR--LEPRGSEIKGAVAKEVVV-RFPSVGKMASIVV------ -----------------------MSVRDIG---ID-VTK-PAGT-----------C---- -S----DAKCPF------------------HGTLPVRGRVFKGEVISSLAAKSATVRWEF AQFVTKYERYARRNTKVVAYSPSCIG--AKKGDIVRVAECRPLSKTKRFVVIEK------ ----------VT-------------------------------------------AGEKK ------------------------------------------------------------ ------------------MAK--------------------------------------- ------------------------------------------------------------ ----------------EYLYRGRTVE--------------------DLKKLSLEEFVTLL PSRARRSLKRGL------SDDQKTLLKDIRA-NAS------------VKTH-VRDLV--- ------ILPEM----------------------------VGKKISVYNG--------KEF V-----------SFDVIPQMIGFR----------------------------LGD----- ----------FAITI-KEVKHSS------------------------------------- -------------PGMGA-TR-------------------------------SSKFVPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------SSKARIKLTGRDVQKLDELCKQIKDIAEKFGVSVKGPVPMPTKRLRIP VLKTPNGSGTGH---GNATWDHWEMRIHKRLLDV-GADQRTLRYIMKIEIPEDVNIQIQL IE---------------------------------------------------------- -MRI--------------RSVQPRKQRAYVYN-APLHTRQKL-VHAALDKKLRKEY---- ---------------------GRR-SLALRKGDKVEVMRG--SFA--GVRGEIKEVDLKD LRVTVDGVKRKKADGT-EVQVR----------MHPSNLRIIEALVD-------------- ---------DKK-RA-----------------------------------RIIERSGGKV --TLTKKKTEKEAKAAHTEGVK--CPLCSETFEN-------------------------N AAANVHVTEKHKEYAQQQ------------------------------------------ --------------------------------MS-LRPAKCYTQP--------------- -K-RPYTRISRRVP--KKSYVVGV-PEPKIRQFQFGDS----KAAFDM-EVALVASRSV- -QIRHNALEAARTNANKYLADNAL----TYFFKIVPYPYHVMRENSMAT-GAGADRLQEG MRRSFGSPVGFAARVRA-GQTLIIARV---A-KDKEAVAREALWRAAAKL--PTPCTI-- ---------------------E-----VKVLK---------------------------- ------------------------------------------------------------ -------------------------------MRH-DTLADALSAIRNAEHVGKKSCVV-P ASALVKNVLALMQKRGYVGEYEFVDDGK-SGFFRIAL----------------------A GKINDCGVVRPRFSVERNKYVKWEK--------------------RFLPSDGFGCLLVST SKGVMDNDEAKKARTGGVLVGYIY------------------------------------ -----M------------EATIEVPEDVTAVMEGA-----NVRVK--GPKGELSRSFR-S P-L----VSVAL-HDGA-FRIT---SR-DER---RATRALVGTWRAHLRNMFTGVTAG-Y EKKMKIIHVHFPMSVKIE---GAR--VA-VQNLLGQKSPRYARIE--TGVEANIEGD--- ----EISVKGTSKDAVGQTVSNIETATKLANR--RDRRR----------FYDGVYLVKAK ------------------------------------------------------------ ---------------------------MPKVHRPRRGSLQYWPRKRAARIHPNVS-I-D- S-AKVTVE-GTRPLAFAAYKAGMTHLIAVDAVKGSPSF--NQPIAVPVSVLDAPPLLVLG FRCYAAS--GRS-SV---ASFDVYADGVPKE-----L-------RV-------------- ----SLK---S----------KHK-----------------------AADVEK------- ---NK--NVDNVRLIVSTQP-----TKSGIAKKTPEIFEVDI-GGKLG---EKIKYASEK LGK-EITVGEVFNEGQFIDVTAITKGKGFQGVVKRFGIRVRGR--KDEQGHRK--IGIH- GPER-MGRIL-YSVPMAGQLGFFRRTEHNKQIFRISS---DG----FSPKGGFVGYGAVP KTMIFLKGSIPGSKKRLVVLRAPLR-------ASSK-GYPI-AIQEVSVASQQGMKTR-- ------------------------------------------------------------ ---MVRIVGYPVQ------I-----------------------------------GEREA K----------------------------------------------------------- -----------AAIVYAP-VSTRNSRAVCRRI--NGMPLEAAKKYLGSLLDESANIN--- -------------------------GRHHTFAAEQILVLLESAQKNAEFRGL---GKTRI RTIIAEEARRMIRR------------KR--KGGRQFKL-THLKVVL-------QEVEKPK ---------EGAKKGPKAMETA------------------TEKKAGDAAADKKSEET--- ----------------------------------VEKQTG-------------------- ---------------------------------EEKTEKTEHA------KEKK------- -----------------HEKHEHAH----------------------------------- ---------------------MGKVIRAQK-------------KGK-SPKYWAPSHRHP- GLPKY-------------IEGTLV--VKDIIHGVARNTPLLRVQGANASA--LMIASEGV ATGDTVSVG--------------AGE---TKPGNVLPLAQIPEGVPIFNIEAQPGDNGAY ARSGGSFAFIVSK-SA----GVVVRLPSKKTRTFNPSCRATIGTPAGAGRKDKPFVSAGA RFHYMKARGKAYPVVSGDKMNAVDHPFG-GRTKK-----G-I----PKTVSRNAPPGAKV GSIAASRTG-------RRKK---------------------------------------- ----MRDIR---------------TRSVRSASN-------P--------------MFEGV RVEKVTLNIGVGEGGDKLQKGATLLNAL-AGQ---TVYMAK--A-LKRTTFGTPRGRPIG AKVTLRGA-KA-EEFIKLALRSKDNKIPEKAFDSTGNLSFGVAEHIDLPGVRYDPKIGVF GMDVCITLGRP-GYRVK-KKARPTRVGKTHLLTREDAMEFMRKKFGAEL-V--------- --- >GCA_003695435 -----MT-THKR--KKVVR-YRASK--THGGGSMKKRR-GAGHRGGRGN-AGSGKRADTK K---------PSFV-----------------GR-----R-F--G-------KY-GFNP-- R-KN--EI--SA-----M-NLRHLED----SVETLVA-KGVF-TK---------SGDTYE CD--LSKIG--VNKLL----GTGKVTKKL-NIVV---ERASSSATEKIEAAGG--KVI-- STTTAH--------------------SQEAVQDQAEQAVSAE------------------ ----------------------------------------------------------MI E--------------------RQIVGANVKEFRI----------------REFIESSL-R NLGLSDAKLQ------KTPLGEKIIIYASRPGLIVGRGGENIKRLTKELKENFDLENPQI EIA-EVENPDLDAAVV----------AEKIANSLEKFGSQRFKGIGYRVMTDSMNAGAMG IEILISGK-I------------PS-------------SRAKTWRFY-------------- ----MGYLKKSGDIALTGVDTHYSEAHLKTGTVG-------------------------- ----------IQVRIM---------------PPSV----------VLPDKI--------- ------------------------E-I------------F-DEPQII--IE--DVSEKE- ---------------------------STKK----------------------------- -------ASKKTVK----KAKKKTAEKKAKTK---------------------------- ---------------------------EESKK-----------------KETAKNKKSDE IEAKNTQD---------------------------------------------------- ----------SVESKETVEKEPSSSEESQK------------------------------ ---ESQETKKSEESSEQPEGSKS------------------------------------- --------------------------------SESS---ESSDSKES------------- NDSQEQQEANAEQ---------------------------------MKVKILGLDGKEKG EKQLPNHFSE-AVRQDLIKRAVEAIQANRRQPYGAHPEAGKRQKGKLSRRRH-N---YKT SYGIGISRVPRKIMSHRGSRFNWVGAVAPGTVGGRRAHPPK-----AQKIWSKKINLKEK RKAIRSALAASLNKKLVEQRGHKVP--E---NFPFIVDSALEEVQKTKELQEVF---KAL GLDKDLQRTKK--TKNRAGVAALRGRKTRRAKGPLVV-V-S-KECA-------------- -----ALKTARNIPGVDVVTIDKVNCELLAPGADVGRLTLYTEGA---VDAL--ENLFVE ---------------------------------VKK------------------------ -------------------------------------------MKNVYSKR---RTVPLR RKREGKTDYKLRLGLL-KSGVPRLVIRKSNAHTSAQIIAYEPQGDKVLVSAHSREL-KKL GY----TQSTSNTPAAYLVGALIAKRAQEK-GVTEAVADFGLQVLPKGGKLYAVLKGAID AGLQVPV--DEEVLPA------QERISGEHIA--HE------------------------ KAQDTRSEFEKVKGTL------------L------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAH-KGKVTKAILLGAKLPCCDNSGA KIIKVVSVKG--AKTSKGRPASAGVGSLILASVKKGKPDIRKQ---VVPAVIVRQRKEFR RPDGTRIKFEDNAAVVLKDDK-GNPKGTIFKGPVAKEAAE-RFPGIAKVASIIV---MN- ------------------------------------------------------------ ---------------------------------TATRGKTFEGTVVSAKMQKTVIVEWEG RRYIPKYERYEKTRTRVSAHNPENIN--AQEGDRVQIKETRPLSKTKHFIITKV------ ----------LG---------------------------------------------KED DYILEKELGEEGKHKKTKKQQKNLEKTEEEQ----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFTYRGMTLE--------------------QLKELPLTELAKHL DAAARRKIKRGF------TEQEVTLLKNLESSSKK------------VKTH-QRQMI--- ------ILPSM----------------------------VGKVIGVYTG--------KEF K-----------DVEIQPEMIGKR----------------------------LGE----- ----------FALTR-KKPTHVK------------------------------------- -------------TGV-Q-TK-------------------------------PKK----- ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLTSSNIDRINEVCASIREISEKTGVQLRGPIPLPTKKLKLT TRKSPCGDGK-------ATWERYEMRVHKRLLDL-GLDERALRLVMRVPIPEGLKIEIEM VD---------------------------------------------------------- -MKK--LFSTK-----WKSSKQPRKQRKFRAR-APLHIKQKF-MGAHLSKELREKH---- ---------------------NTR-SLPVRSGDKVKVMIG--QFK--GKEGKVDRVSRIK GKIYVTGCELVKRDGS-TVPYP----------IHPSNVMITEL-AE-------------- ---------DKK-RI-----------------------------------KGE------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MARLRKFCAYRRL--------------- -E-RPYTRVSKYR---SKSYVRAR-PNCKIVRFVTGDS----KGEYPC-TLELRSEKDI- -QIRDNAIESARQTSNRYL-TKTAGKN-AFRIICRKYPHHILRENPLAS-GAGADRMSTG MKMSFGKVIGIAAQVRK-GEPIFQVDC---N-KKDVPAAKEALRKASMKL--PVSCRI-- ---------------------IE----VAS------------------------------ ------------------------------------------------------------ -----------------------------M-ALN-DTLAAALSKINNAAKSQKTQVEIRP CSKIIKQVLAIMQDNHYVGAHTIREDAK-GDTLVLNL----------------------I DQLNKCGAIKPRHAVAIDEYEKWEK--------------------RFLPAKGFGILLVST NKGIMTHTQAKEQRLGGRLLAYCY------------------------------------ -MANIK------------EQKITLPEGVSASFEND-----ILTVK--GPEGEVSRLFK-V P-L----LVLNI-EGNT-ISLT---TK-RDG---KRSKTLLNTWNAHIKNMVRGVTQG-H EYELKICSGHFPMSVSLK---GNQ--LE-VKNFLGEKVPRVLTLK--EGAQVKVDGD--- ----KIYVKSVDIERAGQVAADIEKLTRITN---RDIRI----------FQDGIYIIKKS GREPFV------------------------------------------------------ ---------------------------MPKAHKPRSGSMQFWPRVRAKRPYARVRTF-V- K-AS-----EAKLLGFPGYKAGMTHCIITENRKHSPNK--GSDVAVPATIIECPPVRIAG VRTYKRA--YLG-LR---AKDTVMAKQ-SKE-----I-----TRKL-------------- ----PVQ---K--------KEHA------------------------LDKIN-------- ---LE--EIEEIRAIVETQP-----KLTGIGKKKPEVFEMAVGGSK-E---DQFNFLKEH FGK-EVSVADVLGEGQQVDVFAITKGKGYQGPVKRFGIGLRAK--KSEKTKRG--PGSL- GGWKGHAHFM-YRIAHAGQMGYHQRVDYNKQILKISS---DPQ--EVNPKGGLVNFGLVK NTYVLVRGSVPGPKKRLLRLEPARR---P-N-PKIE-DQTP-TIQSISTRSQQRR----- ------------------------------------------------------------ ------MAGYSFS---------------------------------------GYEKEKHA R----------------------------------------------------------- -----------ASARDVS-ISTKDAIEIAAFL--RKKPLAKAKTTLERVLAFEQAIPYKR FTN-GIGHRK-----G----QIGA-GRYPQKAAKAFLEVLKSVESNAQDKGL-DTQKLNI IHINAHQASRPVHY------------GR--HSGREMKR-THIEVVV-------GEAQ--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKNLIQQA-------------RGKGSPRYRAPSFKYR- GEAKH-----PLRSKE-LVEGT----IIDLVHCRGHSAVLAACEYDNGEY-RYAIAPEGV RVGDTVQVGS-------------GAE---LKEGNVLPLGELPEGSLVCNIEGVPGDGGKF VRASGTFARVGSQ-LK--D-KVVVILPSKKRKIFHKNCRAMLGIVSGGGRTEKPLLKAGK AHFKAKAKNQLYPVVSGNAQNAVDHPFG-NKRSSRK---S-K----ATPTSRNAPPGRKV GMIAARITG-------QKTGRSSGRRPPKGSRGKKKPENKKGKSALGKK----------- -------------------------------MN----------------------PMQNI RIEKVTLNVGAGKSTDVLDKGVKLLTNI-TGR-TPVRTITQ--K--RIAQWGIRPGLSVG AKVTLRGD-QA-TQILKRLLQAKDNQLSPKQCDDHGNVSFGIPEYIDIPDTKYDPEIGIM GFEVAVTLSRP-GFRVKKRRLKRSKIGKNHQIRQEETIAFLKEQFQVSF-DEDES----- --- >GCA_003650575 -----MV-VHRR--KKKVK-QRGHK--THGWGSKKKHR-GAGNRGGRGM-AGTGKRGDQK K---------PSIWA----------------KR-----Y-F--G-------KR-GFKPKG IIRK--AT--NP-----V-NLLVIEA----RIDEWLK-DGIA-KK---------VDDVYE VD--VRKLG--YDKVL----GYGKLTRKY-RIIA---PAFSEKAGKKLKSAGG--EAV-- V---------------------------EK------------------------------ ----------------------------------------------------------MI E--------------------KKLLSERSKDFQI----------------EEFVMNSF-R NVGVSSVKVQ------RTPLGEKIVITALRPGLVVGREGQNIRRLTAELKKKFGLENPQV EIQ-TVDNPFLDPHIV----------AERIANTLERFGITRFKAVGHRAVQDVMNAGAIG VEITISGK-V------------PS-------------SRAKTWRFY-------------- ----AGYLKKCGDVAIEGVKKAYAIARLKPGVVG-------------------------- ----------IQVRIM---------------PPDV----------RLSDKI--------- ------------------------K-I--------------------------------- ------------------------------------------------------------ ---------G---------------EVKAEEK---------------------------- ---------------------------DENKG---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------TE----------------------------------------- --------------------------------------------SSE------------- Q---------------------------------------------MKVDVVDLGGKVVG KVDLPKQFSE-EYHPNLIKRAVETIQANKRQPYGAKPDAGKRASVRLSKRRR-D---YRA SYGRGISRVPRKILLRRGGQFYFVGAFAPGTVGGRRAHPPK-----AEKDWSKKINKKER KKAIRSALSAAFNRSLVEDRGHKAP--E---NYPFVLIDDFANLGKTKEVKQAL---EAL GLKDEIERSSK--KKVRAGKGKLRGRRYRRKVGPLFV-V-H-EKCN-------------- -----LMKAAANIPGVDVVLVKNLNAEMLAPGGKAGRLTLFTKSA---LDVMEKENLFM- ------------------------------------------------------------ ---------------------------------------------MKRKNKI--FTVQFR RKREGKTNYRKRIELL-KSGKPRLVVRPFLKNIIAQIIEFDKVGDRTIASATGYEL-EKF GW----HFSKGNIPAAYLTGLLAGRKGLKK-GIKEAVLDIGGKTPIKGTRVFACLKGAID AGLDVPH--SEDVFPS------EDRLRGEHIKRYFELGGWNS--KSQFAEMK--K--KGV DVGKITNIFEEVKKKI------------MEM----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKPV-KARVTKGINFGSYIPVCDNSGA KVIRMFAVFG--RKTSKGRYPSAGVGDMIMATVKEGKPEMKKQ---VVLAVIVRQKKEYR RPDGMRVAFEDNAAVVVKDKA-GNPKGTLIKGPVAKEAAS-RWPGISKLASIIV------ -----------------------------------------MAE-----------C---- -K----DKKCPF------------------HGNVKIRGRKLKGIVIAKDLHRSATVLIER MRYLPKYERYEKRLRKIRVHNPSCID--ADIGDEVTIAETRPLSKTKHFVII-------- --------------------------------------------------------AKK- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFTFRGKTLE--------------------ELKQMTLDQFAELL KARPRRKLKRGL------TEAEKKLLKRIREKPD-----------KKIRTH-CRDMV--- ------IIPEM----------------------------VGLTIYVHNG--------KSF V-----------PVSITPEMLGHR----------------------------LGE----- ----------FALTR-KPVKHSA------------------------------------- -------------PGVGA-TR-------------------------------SSAAISAK ------------------------------------------------------------ ----------------------------------------------------------M- ------------PQKARIKIVSTDINKINQVCQYIKDIAEKTGVVMRGPIPLPTKRLRVT TRRSPDGEGT-------ETWDRFEIRVHKRLIDL-GIDERALRLVMRVPIPEGLHIEIEM VD---------------------------------------------------------- -MKK--KFSKS-----WIRSKQPRKQRKYRYN-APLHIRGKF-LHCHLSKELRKKY---- ---------------------GKR-ALRLRKGDKVKIVRG--EFK--GTVAKVSRVDLKR MKVYLENVMRERRDGR-KVAVP----------FDASNLMITELNLE-------------- ---------DKM-RM-----------------------------------KQIERS---- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MARLRKGVAYRNL--------------- -E-RPYTRVSKFR---EKSFIRAT-PRVNIIKFTMGDP----NGKFEY-RLDLVSKDSI- -QIRHNALEASRLTVNRYL-EKKLGKK-GYHFKLRVYPFHILRENPIAA-GAGADRVSKG MKQSFGKPIGSAAQINA-GQSIMFVDV---N-KADIPVAKTALERAIKKL--PCKCTI-- ---------------------K-----IYEIKA--------------------------- ------------------------------------------------------------ -------------------------------MLN-DPLANALSKVLNAELAGKKECIIKP YSKLIKAVFKIMQREGYVGDQKEVDDGR-GGYLIVNL----------------------I GAINKCGAIKPRYDVGVDEFEKFEK--------------------RYLPAKDFGFLIVST SKGLMTHIEAKKAGIGGKLIAFVY------------------------------------ MK-ETI------------EVKLDIPEGVSVSYEDG-----VVCVK--GPLGELKRSLF-Y P-G----VDIKV-DD-K-ITIR---SS-KAT---KREKKMIGTFRAHIKNMFKGVTEG-H VYKLKVCSGHFPMSVSVE---GDE--FV-VKNFFGEKAPRKLKIP--EGVKVKVDGN--- ----DVIVESVDKELAGRTASDIEQLTRRVG---FDKRI----------FQDGIYIYYKD GKYV-------------------------------------------------------- ---------------------------MPRKRSPRKGSLQYWPRARAKKIRPRIKKI-S- --LD-----KAGLSGFAGYKVGMVHVCLLDERKNSMTK--GERITVPATIIECPPLKVFG VRFYKIK---NSTFV---SGETILNQKLDKE-----L-----KRIV-------------- ----QLP---K--------KKTKS-----------------------IDEVK-------- ---LD--EYDDLAVIVYTMP-----KLAGIRKKKPELFELSIGGKDIK---EKVEFVKGL LDK-EIKVSDVFSEGALVDVHAVTKGKGFQGAVKRFGVAIRQH--KSEKTKRG--PGTL- GPWT-PKRVS-WTVPQAGKMGFHQRTEYNKLILKIG----KAD--EINKDGGYLNYGILK SDFVLLKGSIPGSRKRLIVFTAAKR---P-N--DKL-LMVP-KIEKIIK----------- ------------------------------------------------------------ -----MGFNYSI----------------------------------------KYDAEKEA R----------------------------------------------------------- -----------AVGLGMR-ISTKHSVEVCRML--RGMELQKAKDLLQKVLEKKIAVPYRR YRR-DLGHKK-----G-----IEA-GRYPEKVCKEILKLLKDVEANAQVKGL-NTANLVI KHIAAHNGGKPLRY------------GR--RRGRTAKR-THVEIVV-------KEK---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKSLIVQR-------------RGKGTHTFKALSHRYK- GAAKF-----LSLAEG-KLEGV----VVDIVDCPGHSAPLMVVRYANGNE-ALMIAPEGI KVGDVVEIGS-------------GAS---VKTGNVLPLGEIPEGTSVYNIESVPGDGGKF CRASGSFAKVVGK-LP--G-GVLVKLPSKKERLFNANCRACIGVVAGGGR---------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------ME---------------------NPMREI RIEKVTLNIGTGKNIDTLERAMKLLQKI-TGA-KPVKRVAK--K--RIPAWDIRPGVPIA CMVTLRGE-KA-KQVLSLLLDAKDRMLDAKNFDN-GTFSFGIPEYIEIPGMKYDPEIGTM GLEVAVTLERR-GFRVKRRKLRKRRIGKKHRITKEETIAFAEKELGVRI-K--------- --- >GCA_003694805 ------M-MRKR--KKVVK-YRGSK--THGGGSMKKRR-GAGNRGGRGL-GGSGKRGDAK K---------PSLWKV---------------RP-----K-Q--G-------KR-GFTSKR PRRK------------GI-NVGSLSR----LVQRRDV-SGAL-QK---------EGGRIV VD--LSKLG--FEKLL----GGGECTVKL-LVRA---KECSKRAKEKVDHAGG--IVE-- V------------------------FTAPSQKPVAEEGRAGSVK--------GEQS---- ----------------------------------------------------------MI E--------------------RKFVKQNIREFQV----------------KEFIEETL-S RAGLSQVKLQ------RTPLGEKIIVSASRPGLVVGRAGANIANLTAQLKKRFDFENPQI EIE-EVENISLDANII----------AEMIVNSLERFGTKRFKGIGHRAMTEVMNAGALG VEILISGK-I------------PG-------------ARAKTWRFF-------------- ----TGHLKKCGEVARQGVRHAYK------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------MAQGRAG EIPLPRQFAE-QVRPDLIRRAVLAAQANARQKYGAYDQAGKRHTTDLSKRRR-H---YRG SYGFGISRTPRKILSRSGTRFGWVGALAPNTVGGRRAHPPK-----PEKEWGQKVNVAER RKAIRSALAATVEKDVVEARGHRVP--K---GFPFGVEDRFEQVKTTKEAIAVL---KNL GFGGDLERCVR--KT-RAGKGKLRGRRYAVAKSVLIV-V-S-GPCP-------------- -----LVKAARNIPGVDVCAVHELNAQVLAPGAHPGRLTLFTKKA---LERLEKEGLFQG TASSLKARLLKALTGG--------ATTRAGDDPGQQESRSRDAKPKRS-------VKKQG GTAKKLTREQGEVAGA-----------------------------MAKSIA---RTVPQR RKREGRTNYRKRLALL-KSRKPRLVVRKSNKHVVVQLVQYAPDGDVVIEALNSKLL-EKK GW----KHSTKSIPACYLTGLAFGSKALAK-GVKEAVLDLGLHPPVKGSRIYAVLKGVVD AGLNVPC--QENVFPA------KDRLAGKHI----------------------------- -SETVAADWEKMRAEL------------AAQKKKT------------------------- ------------------------------------------------------------ ------------------------------------------------------------ AKETAEGGEDS----------------------MKAV-KAKVAGGLQVGSVVQTCDNSGA KVLKIFAVMK--KKSRKGRLASAGVGDMVHASVKSGRPDMRKQ---VVYAIIVRQKKEFR RPDGTRVKFEDNAAVVLKDDK-GNPKGTIFKGPIAKEACM-RWPGIAKVASIIV---MTK --------------------KEKSNEKK----------E-KVKA-----------P---- -A----SV-TVA------------------GRPVRLRGRTFVGVVVSDKMTKTVTVEWER RLYVPKYERYFIRKSRVKAHNPEEVG--AKLGDKVRIQESRPLSKTKKFVVTEI------ ----------IA------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MARKEFTYRGLTLQ--------------------ELQKLSFDEFVKLV PSRQRRSLQRGL------SEQEKKLREKIRKRDN-------------VRTH-LRAMI--- ------ILPEM----------------------------VGKTVHVYNG--------KEF I-----------PVRIQEEMIGHR----------------------------LGE----- ----------FALTR-KTIKHSA------------------------------------- -------------PGVGA-TR-------------------------------SSAAISVR ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLASTDIDKINQTCEYIKNIAEKTGVVMRGPIPLPRKKLKVT TRRSPCGDGT-------ATWERYEMRIHKRLIDL-ALDERALRLVMRVPIPEGLNIEIEM IDS--------------------------------------------------------- -MKN--VFSKF-----WRSSRQPRKQRKFAAN-APLHLRSAL-LNCHLSKELRKKY---- ---------------------GVR-ALRVRAGDKVRILRG--SRK--GVEAKVERVDVKN LRVFLTKVERQKKEGG-VVPIP----------FHPSNLLITSLDVS-------------- ---------DKK-RS-----------------------------------AKLAKIAE-- -----KKKS--------------------------------------------------- --------EEGR------------------------------------------------ --------------------------------MAKLRKAVAYRRI--------------- -E-RPYTRKSKFR---KLSYVRAT-PHNLIVKYVMGEP----REAYDY-KVLVRSSGSV- -QVRHNALEAARKSANKFL-ETKCGKK-NFCLKIRVYPHHILRENPLAS-GAGADRMSTG MKKSFGKPIGLAAQVRE-GQDLFEILV---K-EPHLSFGKGAAERIKHKL--PVGCKI-- ---------------------V-----VEPCSS--------------------------- ------------------------------------------------------------ -----------------------------M-SLN-DPLANVLSHMKNYEQTKKKEVVTRF NSKLIRGVLEILQKEGYVGSVETVEDAR-GGVLKINL----------------------L GRINDVNVIKPNFQIGKSEFEKYEK--------------------RFLPAKGFGILVVST SKGLMTHEEAKKQGVGGKLLAYCY-----------MSSQERKQEAPLGAAE--GSQNVQA RSKIQI------------KGVVEVPEGVTVSLERG-----VFTVQ--GPKGSLQRKLH-A P-S----VVATV-KEGK-VEFN---AKRKPT---LREKKLINTFKAHLRNMFKGVVEG-H SYELKVCSGHFPMTVSLK---GDV--LE-VKNFIGESVPRTLRIG--ADVKVSVNGA--- ----QILVEGIDKEKVGRVAAAIEQLCRRPG---FDQRV----------FQDGIYIVKKD GKDVA------------------------------------------------------- --------------------------------------MQVWPRKRAKRATARVRSW-P- V-EKFA-S-DARPLGFPVYKAGMTHVMVTEQKKTSHLK--GETLQVPVTVLECPPLKIFG VRGYVRE--GYG-LR---VAKEVLFRT-DKL-----L-----DRRV-------------- ----EVK---KG----------AS-----------------------VKDVEALD----- ---PA--SFAFFTILVHTQP-----KLTGFGKKTPDVAELRLGGGP-A---EQLAYIKEH LTT-PLSVGEVFKEGDVVDAHAVTKGKGFQGPVKRFGIGLKHH--KSEKGRRV--PGSL- GPWSGQGHIM-YRVAQAGQTGFHTRTQFNNIIYKIAD---NPA--DVNPKGGFVGYGFVQ GPYLLVRGSVQGPKKRLITLTHAQR--TM-Q-KKPE-H----VVVAVSVESQQGV----- ------------------------------------------------------------ -----MKNKYAFH---------------------------------------G-DLSSCA R----------------------------------------------------------- -----------ALGRDLP-VSTKQAVELCRFL--RGKPLSKAKAALERVRVREEAVPFTR FSE-GAGHKP-----G-----VGM-GKFPVKAAGALLKLLRQVESNAQQKGL-SS-ELVV VHVCAHKAARPLRY------------GR--HRGREMKR-THVEVVV-------KEAP--- -----------GKKEKPRRQKS-------------------TSQAEKKPEGLK------- ---------------EKKTGAVQKK----------DDK------------KEG------- ----KGAGKEAK-----------------------KESEKS--------QE-------ES ------------------VKQ--------------------------------------- ---------------------MGKSLIQQK-------------RGKGSPTYRRPSFRFK- GAVGY-----FQGG-----KGV----VTHLLKCQAHSAPLAAVQYEDKSY-VLVVASEGV KVGDEVYIHEGDGSAPLADAAEQEAI---FKAGNVLPLSLIPEGVPVHSIELRPGDGGKF CRSSGSSARIVTK-SE--G-KIIIALPSKKRKVLDARCRAVLGVAAGGGRKDKPLLKAGA AFHKARAKNMKYPIIGGSSQNAVNHPFG-NKRTSRK---S-H----AKPAPANAPPGRKV GMIRPRRSG-------RKRGKQ-------------------------------------- --------M-------------------SDNEN----------------------VMRKV KVEKLTLNFGAGKDQVLLKKGERLIKQI-TNI-DPVRTVTQ--K--RIPGWGLRPGLPIG CKLTLRGK-AA-EDVLNRLLQAKGMRLAPSCFDNEGSVSFGIHEYIDIPGTKYDPEIGII GIQASVTLARP-GFRVKQRKIRPRRIHKTHRISREDAVAFMKEAFGVVV--GEEE----- --- >GCA_003650545 ---------MKRK-HTNVY-LKKLV-------------------------EELREKARSE N---------VKLWAR------------------------V----------AN-DLEKST RKRR------------VV-NLTRIEKN----------------VK---------SGEIIL VP----------GKVL----AGGELDKKV-DIAA---FNFSESAQKKIKKVNG--KCL-T IAELMKN------------------------NPKGSKVRIIG------------------ ----------------------------------------------------------MA ET-------------KKITVVNIVVSTSLEHDIP----------------LEKMAATL-S NTEYNPEQFPGLVIRIKDPKTSALIFSS---GKVVCTGARNIQAVHDSIK---------- ----------------------------KIIKSLEKI-GIKITIKPKITIQNIVAAGMIG MDLNLNVLAMKLKNTEYEPEQFPGLVYKLNIAGKKENYKATFLLFS-------------- ----NGKIVCTGTKSEEQVKEAV------------------------------------- ------------------------------------------------DKL--------- --------------------------I--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --INLKKVKQK------------------------------------------------- ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????????????????????????????????????????????-------- ------------MQKARIKIASADIDKVNQVCDQIRGIVEQVGVDMRGPIPLPTKKLKVT TRRSPCGDGK-------ATWERYEMRIHKRLIDV-SVDERVLRLIMRVAIPEGLNIEIEM VGG----MTE----------------------------------------------PQIY AVRT--TANREDQVMDFMSSNIVKKKLKVYAIVRPHGMRGYIFVEAETRSDAEQAAFNIP YARGLLPNVVDFEEISHMLEEVKI-AMTIKKNDIVEIISG--PFK--REKAKITRIDKTK EEVVVELLEA-------AVPIP--------ITLKMDAVRVIRREGE-------------- ---------K---------------------------------------------PTD-- ------------------------------------------------------------ --------ED-------------------------------------------------- ----------------MHSN--LYKCFEILRGMAKKRKFIAYRRI--------------- -E-RPYTRKSKYR---EKSFVRTT-PANRIVRYEMGNP----TGKFQY-KLHLISDTDL- -QIRDLALESMRLTSNRLL-EKTLGRV-NYFLKIMVYPHHVLRENPLAA-GAGADRMSTG MKHSFGKSIGIAARIKK-GQKIMTVAV---N-KSGLATAKKALIRAKQKL--PNSYHI-- ---------------------I-----AEKIA---------------------------- -------------------------------------------????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??? >GCA_002688315 -----MV-VNKR--KKNSR-QQGSH--THGWGAMKKHR-GAGNRGGAGQ-SGSGKRADSK K---------PSIWKN---------------KK-----Y-F--G-------KH-GFTS-- -RKI--KI--KT-----I-NVGYLEK----HLAAFVS-KKLA-KE---------EGDGFL IN--LNDLG--VGKLL----SSGKVTKKL-TVTC---KAASASAIKSIEAAKG--KII-- L---------------------------PKKRDSNGDKKHTS------------------ ----------------------------------------------------------MI E--------------------RDFVKQKKKEHQL----------------RQFISANL-K NVGHSYTELQ------RTPLGEKVIIHTSRPGLIVGRKGQNIGKLTKLLMTEFKLENPQV EIS-EVENPDLVATIV----------GERIASALERFGSNRFKGIMHKTMADVIAAGARG VEIRLSGK-L------------PG-------------ARAKSWRIY-------------- ----GGYLKKCGDAATMHVSKACVVAKLKSGIIG-------------------------- ----------IQISIM---------------PPGV----------IMPDHI--------- ------------------------K-I------------I-------------------- ------------------------------------------------------------ --------EPEEAKT----------EKEETEK---------------------------- ---------------------------KDTEKV--------------------KKEKVEE KKAEE------------------------------------------------------- ------------PDKKTEKKTKTK------------------------------------ -----KKVAEPKTKES-------------------------------------------- ------------------------------------------DAKKT------------- DEK-------------------------------------------MNLEQYNLEKNSEG KIELPSQFNE-PISLNLIARSVITLQLNKRQPYGASPEAGTRVSAQVSRRRR-A---YRG SYGRGISRVPRKVLSRSGRQFFWQGALAPGTVKGRRAHPPK-----ASTQLFKKINKKEN NKAIRSALSAAIAKDFVKKRGHILP--E---GYPFVVNDSLASIEKTKIAKQAL---EKL GFAPELKRTTK--KTVRAGRGKTRGRKYNRKIGPLIV-V-A-EHCA-------------- -----LQKSAANMPGVEIVLVNKLNAELLAPGTVPGRMILFTSSA---INKIKNEKLFM- ------------------------------------------------------------ -----------------------------------------------MKKI---TSIQFK RKRKSVTNYRNRLKLI-LSGKDRLVIRKTSKHIIVQLAKFDEKGDVIITSASSNNL-KKY GW----QSGLKNIPAAYLTGLLAGKQAIEK-NVKEAVLDAGLSKPVSNGRIYTALKGVID AGVKIPA--ATDIFPP------EDRISGKHIS---------------------------- --EKIPGLFKSTKEKI------------MSAKND-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MQAV-PARFFRTLNQGSLIETCDNSGA KLLKITSIKG--SKTVKGRKPAAVISDLVTASVKKGTPEMRKQ---VVFAVIVRQKKEFR RLSGEHIKFEDNAAVVVKDEA-GNPKGTLIKGPVAKEVCL-RWPPIAKISSVIV---MV- -------------------------------------------------------C---- -K----DENCPF------------------HGSLKLTKRSLTGVVDSAKMRRTVNVKREL RVLLKKYERFAKRYSSIKAHNPDCIG--AKEGEIVTITACRPLSKSKHFVVVSK------ ---------------------------------------------------------KQD KTEEA------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------MKKEFIFRGKKLE--------------------ELTKLNLGEFASLL NARQRRSLKRGL------TDQQKILLEKFKKDDK------------NIKTH-CRDMI--- ------ILPDM----------------------------VNKTVSIHNG--------KEF V-----------RLDIMPDMLGHY----------------------------LGE----- ----------FMMTR-RKVSHHA------------------------------------- -------------PGIGA-TR-------------------------------SSASLSVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLVSTDIEKINQVSTSIQEIAEKTGVDLRGPIPLPSKKLKIT TRKCPCGDGK-------ASWDRFEMRVHKRLIDL-ATDERALRLVMRVPLPKGLNIEIEM VES--------------------------------------------------------- -MKT--QFSKT-----WNRSLQPRKQRKYRYN-LPIHLKNKL-LSTHLSAELRTQY---- ---------------------GMR-NIPVKKNDMVKVLKG--SFR--GKTGKVNSVSTKK LAAYIDGVESSRRDGT-KVFVP----------IKVSNLMIIELNTE-------------- ---------DKR-RIK-------------------------------------------- ------------------------------------------------------------ --------NE-------------------------------------------------- --------------------------------MPKMRRSRAYIRI--------------- -E-RPYTRISKFR---KKSFIRIT-PARKIVRFNMGEE----RKR-KY-SLDLVSKASV- -QIRQEAIESARMTSLRWL-EKNV-PG-KFFFRIRKYPYHILRENPLAA-GAGADRVSTG MKQSFGKPIGVALQLKK-GEKLFTVTV---N-EANLEIARKALQRATKKM--PCGFTI-- ---------------------K-----INKEKPVSKKT---------------------- ---ESN------------------------------------------------------ -------------------------------MMN-DPLANALSLIVNAELRGKTNCTITP VSNLIKKILTIMNKDNYIGKFTETETSA-GIVLKVEL----------------------L GAINKCGAVKPRFTVKNNEFEKFEK--------------------KFLPAKDFGFIVVST SQGIMTHIEAKQKSLGGKLIAYFY------------------------------------ --MQKL------------EEIIEIPENITVSIADD-----MLSVK--GPKGEVNKSFF-A E-N----INIST-DSGK-IYLK---SN-RNT---KNERKIANSFKAHILNIFKGVSEG-H HFEMKILSGHFPMTVTVN---DGE--FI-VKNFFGEKTPRKFTLP--KDVTVKVKGD--- ----KVDIESCDKELVGMVMSSIEKLTRRTN---FDRRI----------FQDGIIVV--- ------------------------------------------------------------ ---------------------------MPTIRKPRKGSLAYWPRKHAKRMYPKIRHY-A- P-VS-----ETKLAGFAGYKAGMTHIFIADNRPHSITK--GKSIMFPVTVLECPPLKIAS IRFYKSS--SSG-LR---VANEIFSST-DKL-----L-----AKKV-------------- ----KIP---K--------K-PKE-----------------------LSEIEKK------ ---LG--EYVDVRVNVYTQP-----QLAGINKKRPEIFEVALGGKNVT---EKFNYAKSV LGK-EIPVQDVFKEGQQIDIFAVSKAKGTQGPVKRFGIGLRQA--KSEKGVRG--PANL- GPW--KGNRS-WRVAHAGRMGFHNRLDKNKLLIKIGE---KPE--EVNVKGGFIKYGLLK SNYLLLKGSIPGATKRLIRLVNSYN---P-N-RKLP-TQAP-SIELISLNSPQK------ ------------------------------------------------------------ -------MMYATK---------------------------------------NFDKNTMA K----------------------------------------------------------- -----------AQSISLP-VSLKQSVEVCKFI--QNKKYSRAVKILEDVKLMKIAVPYTR FNRGGTGHRK-----G-----MGP-GRYPVKVCGYMLKLLRSVHANAGQKGL-DTNNLIV KSVIAKQGPKTSRY------------GR--KRGRTAKR-THLEIVL-------VE----- -----------NKKKTVPKKEA----------------DKTTMKNDAAKKE-KPA----- ---------------EIK------------------------------------------ --------------------------------------ATD--------SSKK-----NE ------------------TKTV-------------------------------------- ---------------------MGKNLITQK-------------RGKGASVYKSHSFRYV- GKVKH--HASSKEEESDKVTGK----VKDIVHSSGHYAPIAKVTYQGKES--LEIASFGL RVGDEVSSGK-------------NAK---IKDGNVLPLESISEGSLIFNIESLPGDGGKF VRTSGGFARVLSK-TS--D-QVKVMLPSKKEHSFNPRCRATLGVVAGGGRPEKPILKAGL MSKKRAARGKLYPRTSALSMNAVSHPFG-GSSSAHK---G-K----PLIARKNAPAGAKA GMLRPKRTG-------RGKGRKK------------------------------------- --------------------------------------------------------MKLI KIEKITLNIGTGTDATKLEKGIKLINHI-SGK-KPVKTFTT--K--RIPTWGVRPGLPLG CKLTLRKK-GA-KEMLVRLLQAKENQLASKQFDNVGNLAFGIHEYIDIPGAKYDPDVGII GLEVCVTLERA-GFRVKKRRVKKNPISKKHLITRDEAIDYMQKEFNVEI-K--------- --- >GCA_002730625 ---------MKRTGTTNPL-LRDLI-------------------------MELKKRSNEQ S---------VNLWKR------------------------I----------AL-DLERPT RNRR------------VV-NLSRISRY----------------TK---------ENEIII VP----------GKVL----GSGMLNHKL-TISA---YQFSDQAKDKIERSGA--EIV-P LLDLSKE------------------------KPNGKKIRVIG------------------ ----------------------------------------------------------MI E--------------------RKFIAQKIKEYQI----------------QEYIDKNL-K NVGHSHTKMV------KTPLGEKIVLYASRPGLIVGRKGQNIKELTNTLKKRFRLENPQI EIS-EVGDINLDANIV----------AERITDSLERFGAQRFKAIGHKVMENVMSAGALG VEIIVSGK-I------------PS-------------SRAKSWRFY-------------- ----SGYLKKCGNISIVGVDKAHVQAKLKTGVVG-------------------------- ----------IKVSIM---------------PPGT----------DLPDKI--------- ------------------------E-L------------I-EEKEEK--I---------- ------------------------------------------------------------ ----------EEIK-----------EDDKKSE---------------------------- ---------------------------DDKKD---------------------GGEKETK QDIKKKPK---------------------------------------------------- ------------IKKNVEEKTSSK------------------------------------ -----KITKKAD------------------------------------------------ --------------------------------------------KNE------------- S---------------------------------------------MKLDILDISKKKVG EVALPIQFNE-SIRVDLIKRAVLVLRSNKKQPYGAMLEAGKRASANLSKRRR-K---YRG MYGFGISRTPRKILSRRGTRMYWVGAVSPNTVGGRRAHPPK-----SEKILSKKINKKER KKAIRIGISATIIGELVKSRGHVIP--E---IYPFVLDKNFEDLKKTKEVRDVL---KNF GLGKELERIDK--KKIRAGRGKTRGRRYRMKKGPLIV-I-S-KQSS-------------- -----VTKAIDNIPGVEIVDVKNLNAELLAPGEVPGRLTLWTLSA---IETLEKEKLFLK ------------------------------------------------------------ -----------------------------------------??????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????------------------MQAL-KSRITKAIPIGSQIETCDNSGA KVIKIFTVIG--RKTTKGRVPAAGVADLVMASVRRGRPDMRKQ---VFYAVIVRQKKEYR RADGTRIKFEDNSAVVLKDDK-GNPKGTIFKGAIAKEVCE-RWAGIAKIASIVV------ -----------------------MEANNIG---IK-VAK-PKEK-----------C---- -K----DNNCPF------------------HGSLRCRGRIFTGTVISVKMQKTASVWWER RNFLRKYERYEKRKSGVKAHNPSCIN--AQEGNIVKIMECRPLSKTKSFVIIEV------ ----------SG-KERGF---KERMEAEEESKVK-------------REAKKID---EQT DEA---------------------E--EEVAK---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFMYRGKGLE--------------------ELKKLSLNEMAALL PARQRRSLKRGL------NDQQKILLKNVKQNDG------------LIETH-CRDMI--- ------ILPEM----------------------------VGKTIKVHSG--------KEF I-----------PVIVIDEMIGHY----------------------------LGE----- ----------FVLTR-QRVAHSA------------------------------------- -------------PGIGA-TK-------------------------------SSGALSVK ------------------------------------------------------------ ----------------------------------------------------???????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- -MKT--KFSVS-----WIKSKQPRKQRKYRYN-APLHIKQRF-VRAHLSKELHKKY---- ---------------------NKR-NLGLKKGDGVKVIRG--QFK--NKVGKIEEVSLKK IKVYVTGIEIAKRDGT-KTRYP----------IHPSNLIITEVNMD-------------- ---------DKM-RN-----------------------------------RILGK----- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MARIRKFVSYRRI--------------- -E-RPYTRTSKYK---GKSFVRIT-PNIKVIGFELGSP----KKSFRY-TLNLVSKDDL- -QIRDNALESAKQTSNKIL-EANLGLA-AYHLKVKPYPHHVLRENPLAS-GAGADRFSTG MQKAFGKPLCNAAQIRK-GNTIFQISV---D-KNNIELAKQALTRASKKL--PGSCTI-- ---------------------Q-----MVENK---------------------------- ------------------------------------------------------------ ------MCADNVLGKQQQIWDLKNTLEVKM-SLN-DPLANALSAILIDEKAGKNESTVRP SSKIVKKVLSVMKTNNYVGDFEEKKDGR-GDMIKLNL----------------------L GNINKCGVTKPRYIVKKDEFEKFEE--------------------QYLLARGMGILIVST PSGIVTHNEAKKKNIGGKLLAYCY-------------------------------MENKK SKNKGL------------IIEIELPDKVSAQLDLK-----VLTLK--GLKGEVKRDFS-D K-N----IMIEY-KEGV-VILK---AL-KFN---KVNKKLIKS----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGGFKQHTKMPQIRKPRSGSLQYWPRKRSKRVFARVRAW-T- K-TK-----EAKPLGFAGYKVGMTHLIINDNRKTSTTK--GTEIFCPVTIIETPPLKTLS IKFYKNT--TWG-LK---LISEILAGNLDKE-----I-----KRTI-------------- ----VLS---K--------K-QKK-----------------------ES---------SD KIFPS--DFDFIRLLVHTLP-----GLTGIGKKKPEIFEIAIGGNK-E---EQLNYAKSK LGK-EINVSEVFKEGQQLDIHAVSKGKGVQGPVKRFGISLKRH--KSEKGVRS--VGSL- GGWIAQGHIM-WRVPKAGKMGYHVRMEHNKWILKIG----SAN--EINKKSGFENYGVVK NTCILVKGSVIGAKKRLIRLNEAIS---P-N-KIVP-NEAP-TIQYMNLIQKSV------ ------------------------------------------------------------ ----------------------------------------------------------MA R----------------------------------------------------------- -----------AIGKSLP-ISFKQSIEICDFI--RNKNVNYAKDVLTKVINHELAIPFKR FNM-NVGHKK-----N-----MAA-GRYPKRASMEILNLITHVEANAQFKGI-NTSNLVI THINANKSSKVMHF------------GR--KRSREAKR-TNVEVVV-------QEKADK- ---------NPEKRKINAGKSL-------------------KEQKEAGKQDKK------- ----------------------------------TQEKD--------------------- -------------------------------------------------TQTKAKGKNEV ------------------TK---------------------------------------- ---------------------MGKNLIQQA-------------RGKGSPRYRAPSFRYK- GQSKY-----AKSQKE-TLTGK----IIDFIHCQGHSAPLAQIEYSNGSM-VLIQAPEGV RVGDEVKMGN-------------KID---IKKGNVLPLKNIPEGVAIYNLESSPGDGGKF VRSSGGFAKIITK-MQ--N-LIVVALPSAKRRDFLPECRATIGVIAGSGRKEKPFLKAGK KYYAMKAKNKLWPIVSGVSMNAVDHPFG-GSSSSVK---G-G----PTQASRNSPPGRKV GKIAPKQTG-------KKR----------------------------------------- -------------------------------MN----------------------SMKQI SIEKVTLNIGAGKDQTKLEKGIKLINHI-TGY-NPIKTFTK--K--RIQEWGLRPGLPIG CKLTLRKG-KV-FDLLKRLLEAKENELQASNLDDEGNISFGIREYIDIPGVKYDPDIGIM GLQVCITLKRN-GFRIRHRALKRRTIPKKHRINKEESIDFMKKSFNLKV--GE------- --- >Bin103_genes ------M-ATRL--RKTRR-LRGGR--HMGWGQVGQHR-ASGHKGGLGV-TGMKKHHRST MIK-----EDPD--------------------------H-Y--G-------HD-IPKTPQ PNII------KNW----A-SLRDLDD----LFVKF-G------KE---------EGGKKI VD--LVNAG--IKKLL----GGGKITNAY-SVKV---EQFTASAEVKLKAVGG--EVL-- PKNG-------------------------------------------------------- ---------------------------------------------------------MSA V--------------------KNVIKDNYNMMLL----------------KDYLRDAI-K DAGFSHAEIS------KTPVGTRVALHVTRPGIVIGRKGTGIRALTDKLALDFGLKNPQI SVV-EIEKPELSPSVM----------CNRMQSHLER--GTAFRRATMWTLKQIMEGGAMG VQITISGK-L------------RG-------------DRSAFEKHT-------------- ----QGILPRAGHHAEIIVDEDIAHVKTAMGLIG-------------------------- ----------VRIRIAK--------------------------KEKLVPEF--------- ------------------------E-M------------KDDKTKKGK-SDNK------- ------------------------------------------------------------ --------PVIKVE-----------EILIGDN---------------------------- ----------------------------------------------------KVEVIKV- -EGKK------------------------------------------DN----------- --------AESESAVIEIESKKIETIET-------------------------------- ----LEEEEAKLK----------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MKTATYTTTGTKDV EIELPIIFST-PFRRELIHKACTNLTSHKFQRQGRKPNAGMDVVADSNNP---------- PTGQGVSRVAR-MTG-GGGGRQGQGAEVASTRGGRQAHPPI-----VDKVIYKKLNKKEN KLALCSAIAATASKDLVEFRGHKVQ--GI-ESFPIIVSDDIESIAKTSEITKVL---DAL KLTQDIERLNA--RKPRSGQSRLRGRSKKVGKSVLFV-T-V-NSSN-------------- -----LLQATGAIPGVEVRNVKDLSVLDLAPGSDAIRLTVYSKSA---IEEIGKIKSTHL EVMVKTQ----------------------------------------------------- ----------------------------------------------------MAYSKILR RLREEKTNYKKRGTML-MGKRDFITVNITNENTQVQILKPGMTGDKVIASAHSRYL-LDK GW----KGSRKSVPAAYLTGYLAGKKALGN-GAKDAIMYTGTR--RYTQRMAAALKGVID AGLTVPA--DPETFPP------DARINGEHLTV------KNDV----SKVKS-------- ----------SIDGEVK------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------MAK--QAGKG---VQEF-RPRVTKVLPMGANIVCADNSGA KILEIINVPR--HHTRHRMYASASVGDFCNVVVKKGPAELRKQ---VYGAVIIRQKYAIR RLNGVRVCFEDNAAVLITPE--GETKGTDIKGPVAAEATE-KWPRVANLASMVV------ ------------------------MTHNIG---LK-VKE-PTRE-----------C---- -E----DRHCPF------------------HGGLSIRGKLFDGKVTGSKARKTITLQKDA PIYFSKFKRYARGTSTIHAHVPGCID--VATGDHVLTAECRPISKSVSYVVVEV------ ----------KA------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MVKEFLYRGIPKE--------------------ELDSLSLEKLFLLF NSRQRRSLTRGI------TDGKRKLIEEIKSAKA-----GKLK--TPIKTH-VRDLI--- ------VLPYM----------------------------VGVTVNTFSG--------KEF R-----------PVAITTEMIGHY----------------------------LGE----- ----------YVITN-KKVSHGA------------------------------------- -------------PGVGA-SR-------------------------------SSLYVPLK ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LPKLDDVCGEIMGIGKKTGVKVKGPTPLPVKRLHVA TRKSPCGSGT-------ETYEKWEMKMHRRIINI-NADDKAIRQLMRLKIPDDVYIELSL T----------------------------------------------------------- ----------------------------MIYQ-ATYQTKSKQ-LGSALSKELHKKY---- ---------------------GKR-SVRVSEGDSVKIVRG--EFK--GVDGKVSKISIPK SSVAIEGVKKEKTKGD-KFDVY----------IHTSNLVVTSLNTE-------------- ---------DKW-RI-----------------------------------AKLEGKDPR- ------KQPKVEKVKTET---------KSEPVKE-------------------------- ------VIKETKGAEKVKKDGNEK------------------------------------ ----------------MKDILLTVKIWAFW--LENIMHGANYRDG--------------- -KGQVFTR---------KEYIKGK-PQIKIAKFQGG-K----RGTYQY-CVQLLLNEKI- -QIRHMAIEATRLSANKTL-EKTTGES-GYYSRLRIYPHNLLRENKQIA-TAGADRVSEG MRRSWGKATSLGARVKQ-GQCIMELYV---NGDAHLTAAKKALHGSCVKL--PGTPLI-- ---------------------K-----VIDWNKLSP------------------------ ------------------------------------------------------------ -----------------------------M-PAT-NILANLFVTLYNNETRRKSDCLILP TSKLGVEVLKTLQKDGYIGEFEHIDDKR-GGKFKIKL----------------------L AKITKCGAISPRFKVKTDEYNSWEQ--------------------QYLPAYNRGMLVVTT NQGVMSHHEAVQKGIGGFLIGYVY------------------------------------ MSTKQI---------EKFKDEVVIPEGVTVSLVKH-----MLHFV--GPLGKTHKSFK-- ----SIPVNIEI-TEGK-ILLT---SI-ETK---KRDYAILHTARSIIRNICEGLIIG-Y TIKMKIVFSHFPITVKVE---GKQ--II-IENFQGERAPRITNIV--GNTKVTPKGE--- ----DVIVTGEVWTDVTQTAANIEQKSKVKN---KDHRV----------FLDGIYGFEKT KGIEK--------------------------MV----------------NDVSYGLIEGI ------------RGCILVMG-------ARKFHQPRRGSMGYSRRVRAKSMEARIRAW-PT R-LATD---EPKILAHCGFKAGCVQIVSIDDRDKVPNA--GKQLVTLGTVLVTPPVLILG IRGYSKD--HDG-KH---AEFDVYAEDIPKN-----I-----SKEI-------------S I---------KNI--------AGS-----------------------MENAESR------ ---LK--KIREIFAIVAVSP-----RAAGLEMKKPYIFEAMVSGGDIK---KQFAHVKEL LGK-EIKIDQIFETGATVDVAAITKGHGWQGVMRRWGVKTKQH--KSRKTVRE--VGSL- GPIS-PQSVM-YTVPRAGQTGFHQRVEYDKRIMVMGN--TESDKIKINPDGGYKHFGLVK GDFIILKGSVPGTYKRLIKLRSQIR-----N-APDK-VIKP-NILEVVI----------- ------------------------------------------------------------ ----MGRFNYAFQ---------------------------------------NYDPTRHV R----------------------------------------------------------- -----------ASLREKD-ISHKHAREVAVSI--KGLSIEKARDYLIAVIAKKRAVPFRR YKN-QVAHRS-----D---PGVMS-GRYPQKTAKEFIKVLDNLESNAEYKGM-DLDRLRI VNATVHKGVIVKRFTP-------RAMGR--ATPKNNVL-THVELVA-------KEI---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------?? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????????????----------- -------------------------------MSQT-----------------TESPMKKI SLEKIVLNMGLGKSGEVVNIAKTALEQI-SGK-KPSTRNAK--E--AHRDWGVRKGEAIG VAVTIRGE-DA-IALFKRLLESKGNIVKGKSFDNFGNFSFGINEHIDIPGVKYDPQVGIL GLGISITLTRP-GYGVRARSKHKAKVGKAHIIKSKEAQDYIAKEFGATV-A--------- --- >GCA_009691355 ---------MK----TNLQ-TRTLI-------------------------SELQKAG--K T---------VPLWKR------------------------V----------AE-ELESST RRMV------------AV-NISKLDTV----------------VQ---------EGEIAL VP----------GKVL----SLGEASKKM-TVAA---FSFSEAARAKISV-KG--EAI-S ITELLKK------------------------NPQGKKVRLIK------------------ ----------------------------------------------------------MI E--------------------RKFVGEKMREFLV----------------NEYLHKEL-G AGKYSSFEIK------RTPLGERIVIYTARPGLIVGKGGENIKELTKVLKSKFKMENPQI EVA-EIENANLDAQTM----------AEQIVTTLERFGPKRFKSVGYKTLQRIIDAGAMG AEIAIGGRGL------------PG-------------ARAKTWRFY-------------- ----AGYLKKSGDVSMSFVMYGESTANLKSGSIG-------------------------- ----------VKVRIL---------------PPNT----------ILPDKL--------- ------------------------T-L------------I-DQTAMT--VQVEEVKLED- ------------------------------------------------------------ --------KKETTK-----------DETPVA----------------------------- ------------------------------------------------------EDKKIK ------------------------------------------------------------ -------------KKAAVKK---------------------------------------- -----KVAKKKEEV---------------------------------------------- ---------------------------------KEN------EDQE-------------- ----------------------------------------------MKSAVIGMDGKKGK DVSLPIQFSE-DFRPDLIKKAVLAQQSHSIQPTGTSPLAGLRQSSFITKRRK-H---YKT TYGRGQSRTPRKILSRKGMNFHYVGAVAPNTVGGRVSHPPK-----ASKIWDLKMNVQER RKAIRSAIAATMNPELVKRRGHTAE--S------FVVEQKIEDLKKAKDVYEFL---AKA GLEKELKRIAE--KKIRAGIGKTRGRPYRKKKGPLFV-V-S-KKCA-------------- -----LLTAARNLQGIEVCIVKNLNAELLAPGTNAGRLTVWSDKA---LDVMDKEKLFFA S--------------------------------VKKESKK-------------------- -----------------------------------------??????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????------------------MKAL-TGHKVRALPVGAEIPTCDNSGA KVVKIISVKG--HKTVRRRIASGGVGDLIKASVIKGKPEMRKQ---VVSAIIVRQKKEYK RANGTRIKFEDNAVIVLKDEK-GTPKGTIFKGAIAKEAAE-RWPGISKVSSIVV-MKTKA -------------------------KKNVG---MG-LIV-PSKN-----------C---- -T----DKHCPF------------------HGDLKLHGRVFEGKVINKNLHKTVNVEWER ISYLSKFERYSKSRSRVKAHNPDCIG--AEVGDHAMIVETRPISKTKKFVVVKV------ ----------NK------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MARKEFTYRGKTVD--------------------EIKALDVKEFAKLV PARQRRTLEHGF------NEMQKRLLLKIKKAKEG-----KYK--KPIKTH-CRDMI--- ------VIPEM----------------------------LGLHIHVHMG--------KSY V-----------QIEIFPDMLGHY----------------------------LGE----- ----------FTLTR-NRVAHSA------------------------------------- -------------PGIGA-TK-------------------------------SSSAASVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQRARIKLSSNNIDKMNEIIGSIKDIVEKTKVKISGPIPLPTKKLKIT TRKSPDGEGK-------ASWDNFEMRVHKRLIDL-GVDERSLRLIMRVHIPENVNISIEL LD---------------------------------------------------------- -MKI--EWSKN-----WNASKRPNKQRKFRFN-APLHVQHSF-LGAHLSPELRKKY---- ---------------------TLR-SLPLRKGDKVKILRG--QYK--KKTGKVTRILMKT QKVYIEGIETLKKDGS-KAFVP----------LQPSNVMIIEMELT-------------- ---------DKY-RK-----------------------------------GIVERKSP-- ------------------------------------------------------------ --------KEKK------------------------------------------------ ---------------------------------MGERKFKCYRKV--------------- -K-RAYTRKSRFK---VKGYIKAV-PTNKLVKFNFGDN----KRTFPH-KVYLVSKEKI- -QVRHNALESARTSVVRRL-TKALG-R-DYHMQVRSYPHHVLRENKMIT-GAGADRMQTG MQRSFGRAMGLAAQLKV-GTPIFCVYC---N-KEGIPSARKALLSANPKL--PGRSAV-- ---------------------E-----VD---TK-------------------------- ------------------------------------------------------------ -----------------------------M-AMN-DTLAMALSTILNAEKVGKPTCIVHP ISKTAKAVLEIMKAHHFIGEFTAVEDGK-GGFIEITL----------------------I GGVNKCGAIKPRFAAKVNEYGKFEK--------------------RFLPSKDFGFLIVST PKGIMIQNEAKEKNLGGKLIAFVY-----------------------------------M IEARRL------------RKEITIPTGVNVEV-AE-----FITVT--NKNFHVKKKLT-Y P-T----LIITK-NENK-IIIE---PK-VYT---KREKKIINTFKSHLLNMIKGVQEP-Y EYRVKICASHFPMTVTME---GKK--LI-VKNFLGEKVPRKADIL--ENADVKIEGD--- ----LITITSPDKETAGQIAANFEQSTRITN---RDRRV----------FQDGLWITKKS -RD--------------------------------------------------------- ---------------------------MGHKHHPRRGSLQFWPHARSSKHAPRIRSK-V- E-SR-----DKKILGFLGYKVGMTHLLIKETNTNSHRK--NMDIFTPVTVIECPPLKVYS IRYYAQQ--EDGELR---LVSEVFSKKVDKE-----L-----TRKI-------------- ----RPS---K-----------KE-----------------------NVAPA-------- -------HFDALKVTVYTQP-----KLTGIGKKKPDMVEFSVGGKDLQ---EKSAFAQSL LDK-EIKISDVFKETQFVDAHAVTKGKGFSGVVKKFGVKPLQH--KAEKARRK--VGTL- GSWH-PNKVL-YSVAQCGKWGYHLRTEYNKMTLKIGS---NPK--DINPKGGFVRYGFVK NDYLLVKGSIAGPNKRPIAFSDAIR---I----KKK-AVSG-PIGYVSVESKQR------ ------------------------------------------------------------ ------MENKQ----------------------------------------------HIA T----------------------------------------------------------- -----------AKGENLG-LSRKFSIEVATFI--RGKSLADAKKKMQDVMTLKVAVPFRK YHM-DLGHKP-----G----PMGP-GRFPTKVAKEMLRLLNSAEMNALNKGL-DIENLYV ARVVANKGNTQMKP------------GR--YRGRRAKR-THIEI---------------- ---------TLAEKEKK--------------------------KTEKK------------ ---------------------ETAKTS-----P--------------------------- -------------------------------------------------KEKK------- ------------------TK---------------------------------------- ---------------------MGKNLITQR-------------RGRGTSTYRAPSHRYY- GEIKYR-A-YDDVERNAVVYGT----VKDLIDCPGHMAPLAEIQYDTKEV-ILISAPLNI KVGDIVASGA-------------SAP---VQNGNVLPLKNIPEGTAIYNLECRPGDGGKL VRTAGVCARVVGR-VG--E-GIIVKLPSKKQKTFLGECRATIGTIAGDGRTEKPFLKAGK RMHAMRARNKLYPQTSGVAMNAVDHPFG-SGRGRHA---G-K----PKAPPRWAPAGRNV GLIRAKRTG-------RKR----------------------------------------- -------------------------------MN----------------------VMKQI SIEKVTLNIGTGKPGQELEKGKILLQKI-SGL-KPSETRTQ--K--RIPTWGLRPNLVIG CKTTLRGA-KA-REILLTLLQAKDNKLPIRTFDTHGNFSFGIKEYLDIPTLNYIPEVGII GLEVAVSLQRK-GFRIKRRGLEKRKIPQRHAISKAEAIEFARKDLKLTV-FDSREEAE-- --- >GCA_007131205 -----MA-YNKR--KKNSR-QRGSW--THGWGSKKKHR-GAGHRGGRGA-AGSGKKGDAK K---------PRYWKE---------------KY-----F----G-------KT-GFT--- -SLK--KI--NSKE-KPI-SLSMIRD----QLDKWVA-QGLA-VK---------DNDSFK ID--LSGMG--YTKLL----GTGKINSKL-SITV---PHASGKAKEKVEAAKG--TI--- -----------------------------SIS---------------------------- ----------------------------------------------------------MI E--------------------RKFVAQNIRELEI----------------KEYLYKEL-G KVGLSNVKLQ------KTPLGEKILVSASRPGLVVGKGGANIARLTKELKEKFSLENPQI EIE-EVTDPRGNAAIT----------AEVIANSLERYGPVRFKGIGHKALSTIMDSGAHG VEILISGK-I------------PS-------------SRAKTWRFY-------------- ----QGYLKKCGDISIVGVDKSKQIAKLKSGVVG-------------------------- ----------IQVNVM---------------PGET----------KLPDKI--------- ------------------------T-F------------K-------------------- ----------------------------TE------------------------------ ----------EQLK-----------QEET-AK---------------------------- ---------------------------EEAKE---------------------KEEKKPA ------------------------------------------------------------ --------------KKAVKKKAV------------------------------------- -----KKAAKK------KAVKKK------------------------------------- --------------------------------AVKK------AAKSG------------- DKK-----------------------------------------MNMKLKLMNKEAKESG NIDLPLQFKE-PVRKDIIKRAVITLQLNNRQPYGASPEAGKRASAFLSKRRR-K---YRG TYGIGQSRTPRKVLSRRGTQIYYMGAFAPQTVGGRRAHPPK-----ASKSWEKKVNEKEN RKAIRSALAATVNAELVKKRGHKAP--K---EYPFIITDEFEKITKTKDLVKAL---EAI GFKEELERGNT--TKIRAGKGKARGRKHVTKKTMLFV-V-S-QECD-------------- -----LEKAARNLPGADIAVINNVNAELLAPGAEPGRLTLYTESA---IKKLGEENLFTS TKKKAVKKKE--KPA--------------EEKPAKK--KTTKKKAAKK------------ KTVKKTVKKETEKAKAE----------------------------MKQKTT---YTVRHR RRREGRTNYKKRLELL-KGRQDRLVIRKTNKHIIMQLVRYSPDGDQVLLTANSKEL-EKK GW----KHSLKSIPAAYLTGLIAGKKAKEK-KAASAILDIGLYSPLKGSRIYAALKGAID SGLKIPA--GKEIFPG------EKRLKGEHIASYLE------------------------ KHKSITQDYEKIKSEL------------LK------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKSI-SAKIPKSLPHGALVDTCDNSGA KVLKIFGVKG--HKTVKGQMPSARIGDMVKASVVKGRPDMRKT---VVLAVIVRQKKEYM RPDGTRVKFEDNSAVVVKDDK-GNPKGTILKGPVAKEACE-RWPGIAKISSMIV------ -----------------------MAETQ-------------------------------- ---------------------------------LRTRGRKFTGIVTSDKMSKTVTVAWER RKYIPKYERYEKRRSKVKAHNPESIN--AETGDLVEIEETRPISKTKNFVVTKI------ ----------IK---------------------------------------------KKT E----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKVFTYKGKTLE--------------------ELQKLSMKELAALM PSRQRRKITRGF------SDEEKAFVEKLKKKNN-------------VKTQ-LRDML--- ------VLPGM----------------------------VGKTIRVHTG--------KTY E-----------AITIPQEAIGYY----------------------------LGE----- ----------LVLTR-KRVAHTS------------------------------------- -------------PGVGA-TK-------------------------------SSSNVSVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQRARVKLASTDINKINATCDYIRDIAEKTGVVLRGPIPLPTKKLRIT TRKSPCGDGT-------ATWDRFEMRVHKRLIDV-GLDERALRLIMRVPIPEGLNIEIEM IDA--------------------------------------------------------- -MKS--EFSKT-----WKSSTQPRKQRKYLKN-APLHTKSKF-LNTNLSKTLREKH---- ---------------------GKR-SVRLRTGDKVRILRG--SSK--GKEGKVESINLKE TKVYVTGIEKPKKDGS-KIKVA----------LKPSNLQIVELKLD-------------- ---------DQK-RKQ----------------------------------KLLVKD-K-- ------------------------------------------------------------ --------EDKKNG---------------------------------------------- --------------------------------MAKLMRAVAWRRL--------------- -E-RPYTRRSKYR---EKSYVRTV-PNNRIVRYIMGNQ----KKEYAY-RVLLNSKADI- -QIRHNALESARLTANKLL-EGK-APS-DYLFKLRVYPHHILRNNPLAA-GAGADRMSTG MAHSFGKPVGIAAQVRK-GQPVLEVNV---N-KERLSIAKQALDRARKKM--PCGFSI-- ---------------------K-----IEEIKAKAQAAN--------------------- ------------------------------------------------------------ -----------------------------M-SLN-DPLANVLSHIYNYEKLGKKELITNN NSKVIKEVLRIMQEEGFIGSYEEIDQGKGGKALKVHL----------------------I GSLNKCGAVKPRFRVKLRDYEKYEK--------------------RYLPAMDFGVLIVST NKGIKTNTQAKKESLGGSLISYAY------------------------------------ -----M------------EDNITAPENCTVTQEKD-----FVVVK--GPKGELKRKLT-D K-K----VEIKQ-EGQD-VLLV---YP-EDT---KRAKRLMNTNKAHIKNMLIGVTEG-F TYKLKICSGHFPMTVNLK---NDV--LE-VKNFIGEKVPRTLKIS--SEAKVSIAGD--- ----DITVEATSKEAAGQVAASIEKLTFRPG---FDKRI----------FQDGIYITEKA GKKIVH------------------------------------------------------ ---------------------------MPKKGRPRFGSMGVWPRKKAKRPYARIRSA-P- S-SK-----EAKPLAFPAYKAGMTHIIVRSKDNTPKKA--DINVSMPVTILECPPIRIAG VRLYKKK--GTG-IV---VDKQLNFKA-EKH-----L-----ARKT-------------- ----LQP---KDK-----EK-YAK-----------------------PEDLDKLN----- ---PD--DYEDITIQIYTNP-----KLIGL-KKTPELFEVKLGGNN-K---EKIEYIKNH YDK-NILVTDLFKEGQVIDTHAITKGYGTQGPVRRFGIGLKNH--KSEKGRRK--PGTL- GGWIAQAHYM-YRVAYAGQTGYHQRVQYNNPLIKISD---KPE--EINPKGGFVRYGEIK TSYVLVKGSIPGPKKRMITLSQPVRPPEK-Q-KKV--FTSG-SIRHISLESKQGR----- ------------------------------------------------------------ -----MAK-YAFQ---------------------------------------GF-KENMA K----------------------------------------------------------- -----------ASGLDLG-ISTKASIEIANHL--RGKTTEEAKKLLNKTLKMEQPIPFKR FTD-GVGHKK-----L----ISGP-GRYPQKASKEFLKLIEQAEANAQVKGL-AS-DLKI IHLAAHKASSQFKA------------GR--QRRRMFKR-THLEIVV-------EELE--- -----EKARKKAKKAPAKKEA---------------------PKAEAEEAKPKQETP--- --------KAEPKKQEAPKKEEAPK---------AEAK------PKKADGKKE------- ----EKAEAKPKPKKKAA-PKKQDTPPA--KPEAKKEEAKP--------KKAD-GKKEES ------------------SNKKPEE------------------------------TK--- ---------------------MGKNLIQQR-------------RGKGGQRFRAPDFRYK- GDIKM-----LRKE-----SYT----VKNLVRCPGHTAPLIEAEYNDKTK-SLLVAPEGV AVGDTYNIG--------------GNE---VRAGNILSLKDIPEGTSIFCIEAKPGDGGKF VRSSGGSAKLVSK-TE--K-AVKVLLPSKKQKEFHPECKAMIGIIAGSGRTEKPLLKAGK KHYLMKSRNKFYPIVSGTAMNAVAHPFG-NKRTLRK---S-K----NKPVSRNAPPGRKV GSIAARRTG-------RKK----------------------------------------- ----------------------------MIKM-----------------------KMKEI KVDKVTLNIGAGKDQRLLDKGVKLIKNL-TGK-DPVKTVTQ--K--RIQGWGLRPGLPIG AKLTLRGK-EA-DEMIKRVLYAKENNLEESHFDNHGNISFGLPEYVDIKDAKYDTEIGMM GLQVSITLTRP-GFRIKHRKIRNTHIPSRHQIKKEEAMSFMKEKYSAVI--GEE------ --- >GCA_019429385 -----MK-KNV---SK----FRGSR--TCGGGTSKNRR-GGGSRGGRGN-AGGCKHHFVR NYL-----NGL---------------------------A-Y--G-------KH-GFKRPQ KMLI--YT--PI-----V-NVGELDE----LAEQLVL-DGQA-QK---------EGDMYH IN--LAELD--IDKVL----GGGMVTKSI-VLTV---SQCSERARSKLEEAGG--SVV-- EYISSK----------------------MEQLPEPKE---PLEL---------ADE---- ---------------------------------------------------------MGV E--------------------RKFVQDGLTKAMI----------------NEYFTKQL-E RAGYGGMIMN------RTPMGTQITLLAEKPGMVIGKGGKTIQRLTRDMSYLFNVDNPQI EVQ-EVKVPELNAQMM----------ANRLANALER--GWYFRKAGHNMLSRIMESGALG CQIIISGK-L------------TG-------------PRSRISKMV-------------- ----DGYIKHAGKPAEELVDTGYAMAVKKLGAIG-------------------------- ----------CCVRIV---------------PPGT----------VLPGKFHMLKETAPV APEIAGPE------AK-KSI---KE-V-------------VEKAPDKK-KAEMTNL---- ------------------------------------------------------------ ----------RQVG-----------SIWEHRHDDMDW----------------------- --------------------HPMSRPHDAPAT---------------------------- --AKPEKVGEAKSSKGTSVGDE--IPAKP----------LAGT----------------- ------------VAQPESEKLVSEQTRMNND----------------------------- ----VEEHKHEGY-------------------------DYWHPS---------------- --------------------------------KRVH------KADGD------------- --------DE-----------------------------------MSKAKIMDLTGAQKG EIELPEVFDE-IYRPDLIKRAVLAAQANRLQAYGPTPYAGMQTSADNAGPGR-------- ----GSARVPR-IQN------GNRVARISQARGGRKAHPPK-----VEKDYSEKINKKER LKAINSAIAATGNVELTKQRGHRFD--A---ELPIVAVDEFQDVQTTKDVVGFM---ETI NVFQDVMRAKNG-KHIRAGGGKRRGRKYKRPKSLLIV-V-G-QDNG-------------- -----IVRAARNLPGVDVVMVNKLNAELLAPGTHAGRLAIWTESA---IRALGGVA---- ------------------------------------------------------------ ---------------------------------------------MATGPR---YKVAFR RRREGRTDYHQRLKLL-VSKQARVVARRSLKHMKLQLVVPKPEGDRTLVHADSTEL-GSY GY----TGPTGNTPSAYLTGLLFGYKAQKA-GYENAVLDMGLQVSSKGSRIYAALKGIVD SGLDVPH--NPEIFPG------EPRIRGEEIKEYT------------------------- -GIDIPAMFDETLAKI------------KNEFGED------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MRGM-KANIPRALNAGARLDCVDNTGA RQVEIISVKR--YRGVKNRHPKGGIGDMLVVSVKKGTPEMRKQ---IMKAVVVRQKKEFR RPDGLRVSFEDNAVVITDDE--GIPKGTEIKGPVAREAAE-RFTKIASVASIIV------ ------------------------MTRNIG---LD-VDA-PSEE-----------C---- -I----DINCPF------------------HGTLSVRGQVFTGSVVASKMDKTVVVKRVF EKLIPKYERLEKRQSKIHAHNPPCID--AKEGDEVKIAECRPLSKTKTFVVIEV------ ----------TK------------------------------------------------ ------------------------------------------------------------ ------------------MAKKTST----------------------------------- ------------------------------------------------------------ ---------KLPKRKGEYTYRGKTVD--------------------ELKTLSTEEFSQLI PARQRRTIKRGL------SDEHKKIMQKIKEGETD------------IRTH-RRDMI--- ------ILPEM----------------------------VGRNLEIYNG--------KSF E-----------KIEVIPEMMGHY----------------------------FGE----- ----------YSMTR-KRVSHGS------------------------------------- -------------AGVGA-TK-------------------------------SSKFVPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------AQKARIRLTGTIPSTLDNVCEQVKSIAIKTGVNISGPIPMPTKKLMVP TLKSPDGEGT-------STWDHWEMRVHKRLIDL-DADERALRQLMRIQVPKDISIEIVL TN---------------------------------------------------------- -----------------MKSTQPRKQRKARYN-ATLHQRQKL-LSASLSHELRAKY---- ---------------------NRR-NLPVREGDTVMVMRG--DHT--GTEGKVELVNLKH TTIVVEGVSVPKADGT-EVPRP----------VHPSNVMITKLNLS-------------- ---------DEM-RE-----------------------------------LTLSRGGE-- -----EQ----------------------------------------------------- ------------------------------------------------------------ -------------------------------MAG-KRPAKTFRNYN-------------- SR-RSYTQ---------RKYMGGV-PGNKIVHYDMGNL----KAEFPV-KLSLVADESC- -QLRDGALEAGRITANRLL-VKMVGVQ-NFHMKLRVHPFQVIRENKQAT-GAGADRVSQG MRQAFGKAVGLSAKVGK-GQKIFTIST---T-KEGFLTAKDALRRCGMKL--STPVKI-- ---------------------V-----VDEGQKLVD------------------------ ------------------------------------------------------------ -----------------------------M-VLL-DPLADALSTMKNAESTGKSHCIIHP ASKLIGNVLKVMQDMGYVGQYEFIDDGM-AGMIKVEL----------------------I GKINKCGVIKPRSAVGYRDFEKWEK--------------------RYLPASNFGALILTT PNGVQSQHDARAQTVGGQLLAYVY------------------------------------ -MAKEI------------KRAVEIPGEVKVVMEGS-----MCTVT--GPKGTISRSLW-Y P-G----IIIEL-VDNQ-ITVD---SP-NPR---KKQQAMIGTISSHINNMVRGVTVG-F SYTMKMVYSHFPIQLKVE---GGA--LN-IGNFLGEKKPRKARIM--GETKVDVKGD--- ----EVVVTGINIEDVGQTAANIQQATKIKR---FDPRV----------FQDGIYVVEKA RA---------------------------------------------------------- ---------------------------MANVHRPRRGSLSFSPRKRAKSQVPTIRSW-S- I-SDD----EPKMGGFAGYKVGMSHVIMMDDKPKSLTE--GMEISVPVTVLEVPAMRIAA IRAYGKKG-PYG-VK---ILGEALSNDLDPT-----L-----DRKM-------------- ----VRP---KKA------KPDKA-----------------------LASMEKL------ ---VEEGAVENIHVITYTLPS----QISGVPKKKPDVMENRIVGGNVA---ARLEYAKSI LGK-SITVSDVFNSGDIVDTSAITTGKGTQGPVKRWHINLMKS--KHSRQGSLRQVGTL- GPWN-PSRVS-WRVPQLGQTGYHQRTEYNKRILKIGG---NGE--EVTPAGGFLNYGEVN GEYLLIKGSVPGPKKRLIRLRPAIR---S-E-IKN--VGAP-QISHISVESKQG------ ------------------------------------------------------------ ----MSRIQYSVQ----------------------------------------ADPETTS T----------------------------------------------------------- -----------AMGHELH-ISPRHSREICRAI--KGMKSERAKQYLKEVAALKTAVPFKR HND-SMGHRR-----G----PMAA-GRYPQKAAKEFIKILVNAEANAEYKGL-DPQHMKI SHISTKQGRVIHGYMA-------RARGS--SSPKNTET-VNIEVVL-------QEVQ--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRIISQN-------------RGRGSPTYRAPSHKFK- AELKH-----IKVDKDQTVTGD----VIEILHDTARSAPIARVKLDNGEE-RLILVPEGI SVGQQISCGI-------------SAE---VKPGNTLPLGEIPEGVLVCNIENRPGDGGQF ARSSGVYAVLVAH-DV--G-KSVVQLPSGVMKWLSPLCKATIGVVAGGGRTDKPFVKAGK KYHKLKTRATKYPRVRGVAMNAINHPFG-GGGWQHP---G-R----PTTVSRRTPPGRKV GSIAARRTG-------KR-------------------------------MC--------S LLELINQNSIWEVL-------------SVSESN----------------------VMRTP RVDKLTVHIGVGESGDNLNKAEDILNTI-AHQ-QGVRTMAK--R--TFLAFHIKKHEPIG CKVTLRGE-LA-ESFLRTSLGIIENQLKESQFDKTGNFSFGIEEHTDFPEMKYDPNIGIY GMDVTVSLVRP-GYRVSRRRIQKQKVPNRHKLTKQDAIAYVKDAYGVEV-LA-------- --- >GCA_003352285 ------M-ATRL--RKTRK-FRGSR--NHGWGQVGQHR-ASGHKGGLGV-SGQLKHHYSG MLK-----TDPD--------------------------H-F--G-------HD-STVPPH PTIT------RKW----A-SVRDLDD----LFTRY-G------KQ---------EGEKKV ID--LQGNG--FDKLL----GGGKITSAY-TVKI---NRFTASAEEKVKQAGG--EVL-- ADNG-------------------------------------------------------- ---------------------------------------------------------MSA V--------------------KNVIKDNYNMMLL----------------KDYLREQI-K EAGFSHAEIS------KTPTGTRVSLHVTRPGIVIGRKGVGIRELTEKLASDFELKNPQI SVV-EIDKPELSPSVM----------CNRMAAHLER--GTAFRRATMWTLQQIMNNGAMG VQITISGK-L------------RG-------------DRSAFEKHT-------------- ----AGILPRAGHHADVIVAEDIAHVKTAMGLIG-------------------------- ----------IRIRIAR--------------------------KEKFVPEF--------- ------------------------E-L------------KTSKAKK-------------- ------------------------------------------------------------ ----------HQVK-----------DELTGKM---------------------------- ----------------------------------------------------RDET---- -AAEK-------------------------------------------K----------- --------ARTESEQIAMEEEKIKEMEL-------------------------------- ----LDDEEENLK----------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MKVKALSITGSADG DVELPQVFET-PIRKDLIHKAYVNLDTHHYQPKGTHPTAGMDVVARSNDP---------- PTGHGSARIAR-MRG-GGGGRQGEAGGVASVRGGRQAHPPN-----VERVIYKKVNRKEN KLALCSAIAATASKELIQKRGHKIE--GI-ESFPMVVSNEIENISKTKDLLKVL---DSL KLTQDVERLSK--RKSRTGKSALRGRGKKIGKSILFV-T-K-SADK-------------- -----IAQACGSIPGVEVRTANQLSVLDLAPGSDPIRLTVYSKNA---IEEISKIKSTHM EIMVKVK----------------------------------------------------- ----------------------------------------------------MAYSQILR RLREEKTNYRKRKTML-MGKRPFITVQITNENTQVQIHTPEMTGDKVIASAHSHYL-LKK GW----KGSRKNIPAAYLTGYLAGKKAVGK-GSKSAILYTGTR--RYTQRMAAVLKGVVD AGLEIPA--DPESFPP------EERITGQHLTV------KNDV----NQFKS-------- ----------QIDSEVK------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------MSQGRSR--GKAKG---VAEF-RPYVTRALPVGAQIICADNSGA KILEIVMVQK--TKTRVSRLPAAAVGDFVNVVVKKGPAELRKQ---IYGAVIIRQKYPIR RLNGVRVAFEDNAAALMTPE--GEMKGTDIKGPVAAEASE-KWPRLANLASMVV------ ------------------------MTRNIG---LP-VKT-PEKE-----------P---- -EA--WDKKNPF------------------NGTLAIRGKLFEGTVVKANAKNTVVIEKES PIYFSKFKRYARGKSSIHAHVPSNLD--VKQGDRVLAAECRPLSKSVAFVVVEV------ ----------KE------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MVKKFEYRGMPLT--------------------ELEGLSLENLFKLF NSRQRRSLTRGI------TDGKRKLIEEIKAAKA-----GKSK--NAIKTH-VRDLI--- ------VLPYM----------------------------VGVTVNVFSG--------KEF R-----------PVTIIPEMIGHY----------------------------LGE----- ----------YVITN-KRVTHGA------------------------------------- -------------PGVGA-SR-------------------------------SSLYVPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------TQSARIKLTSTSLPKLDGVCGEIMGIGKKTGVRVKGPTPLPVKRLHVA TRKSPCGNGT-------ETYEKWEMRMHRRIIDI-NADDKAIRQLMRLKIPDDVYIELSL T----------------------------------------------------------- -------------------MKPTKMRNNQIYR-ASLTTRSNQ-LGSTLSKELRKKY---- ---------------------GKR-SVRIIEGDAVKVIRG--EYK--DVDGKVASVSVEQ NSVAIEGIKKEKGQGD-KFDVL----------IHTSNLMITSLNTS-------------- ---------DSW-RM-----------------------------------SKLEGKKPQN VKKEMPKEVKEEAKKPEP---------KKEAPKE-----------------------KKT DIEKKPTKKESKPAKKKEKSE--------------------------------------- ------------------------------------MHGANYRKS--------------- -NGQPYAR---------KKYIKGK-PQIKIAKFQTG-K----MGDYDF-CVQLLVNEKI- -QIRHMAIESTRLAANKTI-EQVTGET-GYYSRLRVYPHVLLRENKMIA-TAGADRLQEG MRRAFGKAVSLAARVKQ-GQVIYEAHV---K-KEHLEHTKKALKSACVKL--PGTPTI-- ---------------------K-----VIPLK---------------------------- ------------------------------------------------------------ -----------------------------M-PAT-NILANLFVTIYNTEARRKNECLVYP TSKLGINVLKVLQKDGYIGEFEHIDDKR-GGKFKISL----------------------L AKITKCGAISPRFKVKKDEYAAWEQ--------------------QYLPSYDRGMLLVTT NQGVMSHHEAASKDLGGFLIGYVY------------------------------------ MSTKQL---------EKFATSVKVPEGVKVSLDKH-----MLLVQ--GPLGKTYKNFK-- ----KIPVDIKV-EGNN-VSLK---AL-DTR---KKDYAILNTSRSIIKRLCEGVVSG-Y TIKMKVVFAHFPITVKTK---DDK--VL-IENFQGERSARVCQII--GKTKVNPKGE--- ----DVIITGHVLTEVTQTAANIEQATKVKG---KDHRV----------FLDGIYIFEKT SGIEK------------------------------------------------------- ------------------MG-------HRKNSQPRRGSLAYLPRGRAKSFEARIRTW-P- D-VNSE---EPKLLAHVGFKAGCIQVVSIDDREKTPNH--GKQLVSLGTVLVTPPITVLG IRGYSNS--TTG-LH---AEFDVYSEDIPKD-----I-----AKHI-------------S L---------KNK--------EGA-----------------------LEKAEKM------ ---LG--RIKEIFALVAVSP-----NVIGIEQKKPYIFEAAIKGGDIQ---KQFNYVKEL LGK-EVKIDQVFELGGSVDVAAITKGKGWQGVIQRYGAKKKQH--KSRKTVRE--LGSL- GPIS-PQNVM-YTVPRAGQMGLHQRVEYDKRILIMNN--TDDKKLEINPEGGYKHFGLVK GDYIVLKGSVPGTYKRMVKLRSQVR-----N-VPPK-ITKP-NILEIVV----------- ------------------------------------------------------------ ----MGRFDYAFQ---------------------------------------NYDTTKHV R----------------------------------------------------------- -----------ASLREKQ-ISHKHAREVSKQI--KGMTIEKARDYLTSVINKERAVPFRR YKT-NVGHRS-----D---PGVMA-GRYPQKTALEFIKMLDNLESNAEYKGM-DLDRLKI VNATSHKGILIKRFTP-------RAMGR--ATPKNNVL-THVELVA-------QEV---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRPLVRR-------------RGRGGMQFRATVTGKV- ARSKY-----PSFTLSEQHEGK----VIDLVHERGRDAPLAKIRFEDGSV-SFVPAVLGT KVGDTLEFGL-------------KSK---IQDGNVISIQNIPDGTIVCNLEKQFGDGGSI VKSAGTNATIFSH-NE--E-GVTVKLPSGKFATFNPKNRAMIGTLSGGGTSERPFMSAGR KWRNFRSRGRKYPIVRGVAQAAYVHPHG-GGRHQHV---G-Q----SSTVSRDAPPGAKV GSIAARKTG---------RARIKERK---------------------------------- -------------------------------MSQT------------------ENIMKKI SLDKVVLNMGVGKSGDAIDVAKKALDQI-SGK-KSCARDAK--E--TQRDFGVRKGEPIG VAVTVRGK-DA-EELLKRLLQAKGNQIKGRSFDDFGNFSFGILEHIDIPGIKYDPNIGIL GLDVAVNLTRP-GYNIRKRSKHKASVGKTHRISEDEAKEFMENQFGAVI-V--------- --- >GCA_003694525 ---------MKRTGPTNPE-TKALI-------------------------GALRKESASS A-----------LWKR------------------------I----------AD-DLEKPS RARR------------AV-NISRIARN----------------SK---------EKDTII VP----------GKVL----GSGAIKHSI-TVAA---LSFSAGAKERIEAAKG--KAL-T ISELLKQ------------------------KPKPQNVRIIG------------------ -----------------------------------------------HIGMVTQETYLFH D---------------------------TIRMNLLYAKPDAT------QAEKEIKKIIPE EAGISQVLFD--------PQRSRVIIEAEKPGLAIGKQGSLLKEIREKV-----LWVPIV RRT-----PALRSQIIENIRTVIYENSDYRRKLLDKIGHRIYDGWLREKKNEWVRVTHLG AARQVGRSCILLQTP-------ESRI--LLDCGINVAG-EGSDMYPILDAPEFNIQQLDA IVLSHAHLDHSGFIP----------YLYKMGYRGPVYCTEPTRDVAALLMLDTVKIAKSE NKEPLYDIEDVRQFVLHCITLNWEEVSDI--TPDVRL-TLYNAGHILGSSM--------- ----------AHLHIG-NGLH---N-LLYTGDLKYGRTPLFDPAHTVF-PRLETVIMEG- -----------------------TYGGRQDI----------------------------- ------GLPAREADELLCNYI----KETIKRGGKVLMPVLGSGKAQDIMVMIEQMVRRGE LEEIPVYIDGMVWDITAIHTAYPEFLNTHLRKAIFHKDQNPFLHPMFKRVGSAKERKQVI ENTGPAVI----------MATSGMLVGGPSV------EYLQNLADNPKN----SVI---- ----FTCYLPEGTLGRRVFGGEPE---------------L-------------------- ---IYKKDGRTQVTPIKLEVVKVA-V-----------SDHSDRKQLM------------- ---------------NFIFKCQP---------RPKKVIVQHGEASKVIDLASALHKQGRL ETLAPRNLESIRIK-????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????????????????????????????????????????????-------- ------------MQKARIKLASIDIDKLNTTCNYIKDIAEKTGVEIRGPIPLPTKRLRLT TRKSPVGRGT-------ETWERYEMRVHKRLIDL-GLDERALRLVMRIPVPEGLNIEIEM IDV----MTENEHEKDQKAPEGVPTIAGARKVEEE----TPKAEEKEKKEEKPEVSTHIF ALRT--TANREDQVMDFLVSNIKKKSLPVYSVIRPHGMRGYIFVEALDRQTAEQAAFNVP YARGILPKEIQYSEIEHMLEQVKR-EMNIKKNDIVEIISG--PFK--REQAKVTRIDKSK EEVVVELLGA-------AVPIP--------ITVKMDAVKVIRRESE-------------- -------------------------------------------------------DSP-- ------------------------------------------------------------ --------NP-------------------------------------------------- --------------------------------MARLRKFCAYRRV--------------- -E-RPYTRFSKFK---KYSFIRAR-PGNRITRYTSGA-----QLDYPF-NVHLVAKSCV- -QIRSQALESARLAANRAM-EKVLGKQ-GFFLQIRLYPHHVLRENPLAS-GAGADRLSTG MKHSFGKPIGVAAQVRD-GQEMITIRT---G-KENVRLAKNALRAAAHKL--PLKCSV-- ---------------------V-----VKEL------------------------ARA-- -------------------------------------------????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??? >Bin391_genes ------M-RHTR--KKNSR-QKGSK--THGWGSMKKHR-GAGNRGGRGK-AGTGKRADTK K---------PTIINLF-------------GNS-----Y-F--G-------KT-GFTSR- -SMK--RV--VP-----I-NVSQLQV----MFE-----QGQV-KN---------D----- VD--LKKIG--FNKLL----GAGQITAKL-TIKV---DVASPRAIEKVKKAGG--SVE-- V---------------------------LKTNTE-------------------------- ----------------------------------------------------------MI E--------------------RKFVAEKMRDFMV----------------RTYLSNFL-G TGKYSSITIK------KTPLGEKVVVYTAKPGLIVGKKGETIKLLTKVLKSKFKMENPQI EVS-EITNPGLDAQTM----------AEVIVTVLERFGPKRFKSTGYRTLQRIMDGGAVG AEILISGRGL------------PG-------------SRAKSWRFY-------------- ----AGYLKKSGDVAVSQVKYGKSIANLKSGTVG-------------------------- ----------VKVRIS---------------PPDI----------QLPDKI--------- ------------------------T-L------------K-EQKEMT--IDVEEIT---- ------------------------------------------------------------ --------EKEEVK-----------EEKPK------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------AKKKVKK---------------------------------------- -----KTVKKK------------------------------------------------- ------------------------------------------------------------ -------------------------------------KIYKSGVSTMKVDVKGMDGKKVK DANLPRQFTE-AFRPDLIKRAVLSIQSHKIQPYGAFTRAGLGYSSMVSKRRK-A---YKT TYGSGNSRTPKKVLTKRGLHFYYQGATVPFTVGGRRAHPPK-----AEKIWDEKININER RKAIRSAIAATMVPTLVKKRGHTTE--S------IVIDSKVEELKKTKEVFDVL---TKM -MPEEMKRVEY--RKVRAGKGKGRGRKHRIKKGPLFV-V-S-NKCS-------------- -----LIKSAMNLQGVDICIVNELNAELLAPGCNAGRLTIWTEGA---LEKMEKEKMFYR K--------------------------------VKKVEK--------------------- ---------------------------------------------MRRT-----TFVKYR RKKEGKTNYSKRLRML-KGERARLVVRKSLKYITAQLIKYENDGDKTLISVSSKEL-AKY GW----KNYSRNIPAAYLVGLLIG---KRA-KVKDAVFDIGLNN-TNSTILFAVLSGAVD AGMNIPH--SEDLYPK------KERIEGKHIS---------------------------- --EEFVKNFKVVKEKI------------ENEK---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MVKKEFSYRGKSLK--------------------ELQEMDLKELAVLL PARQRRTVLRGF------TDGQKRLLARIQKTKEG-----KTK--KPIKTH-CREMI--- ------VLPSM----------------------------VDMTIHIHKG--------KNF E-----------QVLIQPEMIGHY----------------------------LGE----- ----------LALSR-QRIAHSA------------------------------------- -------------PGIGA-TK-------------------------------SSAAASVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MPKVRIKLKSIKIEGLNKICDQIKEIASKAGIPISGPIPLPTKKMKIT TRKSPCGDGT-------ATFDNYEMRMHSRVIDL-PADDRVLHAIMRLYVPRNITIKIEM ID-----MEEETN--------------------------------------KEEMCNKIF ALRT--TANREDQVVDFLSSNIEKKKLDVYAIVRPHGMRGYIFVEAKDRQIAEEAYYGIP YAKGLLSKPVEYKEIEPMLEQVKV-QMNIQRNDIVEIISG--PFK--REKAKITRIDQQK EEIIVELLET-------AVPIP--------ITLKMDAVKVIRRESE-------------- ---------E---------------------------------------------GVE-- ------------------------------------------------------------ --------ED-------------------------------------------------- --------------------------------MVGLRPFRCYRRI--------------- -K-RAYTRKSKYK---AKGFIKAV-PTSKIVKYNYGNT----KKEFPI-KMNLLSKQRM- -QIRHNAIESARVMVVRKL-NKVLG-R-NYHLQIRIYPHHILRENKMIT-GAGADRMQTG MQHAFGKAMGLAAQVKI-KQPIFTVHA---E-KEAIPHIKAALKACTFKL--PCRCSI-- ---------------------V-----LL------------------------------- ------------------------------------------------------------ --------------------------------MN-DPLATTLSNIQNAEIVGKDICLAKP MSKVIKKVLEIFKDNHYLGEVKEINDGK-GGIFEINL----------------------I GQINKCGVIKPRFSVKLEGYEKFEK--------------------RFLPAKDCGLILVST SQGIMTHIQAKEKRLGGKLLAFIY-----------------------------------M IEVHRL------------RKEIAIPQGVEVNLDVD-----TLTVK--LDKNENKKKLF-Y P-N----VRIEI-KEGK-IILE---PK-KFS---KREKKIINTFKSHILNMIQGVQEI-F EYRVEICSSHFPMTVNID---NGM--IV-VKNFLGEKVPRKAKIV--EGVDAKIEGN--- ----IIVLKASDKEMVGQTAANCEKATRITN---RDRRR----------FQDGLWITHKA GKDM--------???????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????--------- ----------------------------------------------------MTKKEHTS S----------------------------------------------------------- -----------VNASNLD-VSKKHAIEIGNFI--RGRNLDKAKRLMEEVIVKKTAVPFKI FNM-DVGHKK-----G----KIAA-GRYPVKAATRILGLLNSAESNAEDKGL-DVDTLYV AEFITNKGTGAMHQ------------GR--HRGRAMKR-THLKV---------------- ------------------------------------------------------------ ----------VLEEREVKKK---------------EENP--------------------- ------------------------------------------------------------ -------------------KEAKKK----------------------------------- ---------------------MGKRLITQR-------------RGRGTSTYKSPSHRFK- GEIKYK-R-LDDTEKDGVVYGS----IKDLINCRGHSAPLALVKYD-KEE-VLISASLGM KVNDVVASGA-------------TAP---VQTGNTLPLNNIPEGTLIYNIEIRPGDGGKL VRTQGSFAKIVGK-VG--D-IITVVLPSKKQKKVNGRCRATIGVIAGGGAKEKPILKAGK RMHAMRAKNNLYPKTSGVAMNAVDHPFG-SGRGRHA---G-K----PKTAPRWAPAGRNV GLIRAKRTG-------KKK----------------------------------------- --------------------------------------------------------MKTI QVEKITLNIGAGKPGPELEKGIILLKAI-SGG-NPCETKTK--K--RIPGWSLRPGLTIG CKVTLRKE-DA-KKVLSRLLAAIDHKLSIRAFDKQGNFAFGVPEYLEIPEMEYIPEVGII GLEVAVTLQRP-GFRIKRRSQKTKSIPTRHRITKEEAIGYAKKEFKIKL-KEEEEEE--- --- >GCA_003599145 -----MT-VNKR--KKNSR-MRGSH--THGGGAKKKRR-GAGHRGGRGN-AGSGKRGDAK K---------PSYW-----------------KN-----P-L--P-------AP-KFKS-- R-QK--PD--KV-----L-NISDIEI----RFENLLK-SGVM-EK---------QGDIYA VD--LTKMK--VDKLL----ATGTPTRKY-KITV---GKASKKAVEKIKAKQG--EVL-- ADGMV------------------------------------------------------- ----------------------------------------------------------MI E--------------------RKFIKQNMKEHAI----------------KEYISQHV-S NAGHSYTKLQ------RTPLGEKIIICASRPGLVVGKSGANIARLTRELKEKFHLENPQI ELV-EVEQPDLDPSVV----------SESIAGSLERYGSARFKAIGHAAMTKVMKAGALG VEIVISGK-I------------PS-------------TRAKSWRFY-------------- ----QGYLKKCGDIALVGVHKAYASAKLKTGIIG-------------------------- ----------IKVSIL---------------PSTT----------VLPDHI--------- ------------------------E-F------------V-EQKQEL--VE--EVT---- ---------------------------ETDS----------------------------- --------AVQEIK-----------EQVAEET---------------------------- ---------------------------QPAKK---------------------------- ------------------------------------------------------------ ------------PAKKATKKTKAK------------------------------------ -----KKDES-------------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MKLPIINNENKKVG EKTLPKQFNE-LYRADLIKRAVLALQSN-RNVYGSDPRAGKKASARISKRRR-D---YRG SYGKGISRTPRKVMTKKGTQFNWTGAFAPNTVGGRRAHPPK-----SWKIVEQKINDKER KMALRSAIAASLNNQLISKRNHVIP--T---QFPFIISSEFENITKAKDFFKAL---TSL GFEKELARVKE--KKIRAGKGKIRGRKYDTKKGPLIV-V-S-KECP-------------- -----LLKAGKNIHGLEIVAVKQLNCELLAPGCTAGRLTLYTDAS---VDLMQKENLFMV AK---------------------------------------------------------- ---------------------------------------------MASKKK---KVIPYK RKRNGRTNYKVRLKLL-LSRKPRLVVRKSNTKLVAQIVEYVPSGDKIISAAVSTEL-KKY GW----SFSLKNIPSAYLLGVLIAKKALDK-KVNHAIFDIGSQRSNKGSKLYAVLNGAID AGMSIPA--DNSIFPS------KDRVSGKHIAGYFSSAAGNQ-------FSNYKK--EKL SVQSMEKQIEEIKHKI------------LAK----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAV-KASIGKPLPVGAYIETCDNSGA KIIKITAVIG--HKTVKGRYPAAGVSDLISAAVKKGKPDMRKQ---VVFGVIVRQRKEYR RPDGTRIKFEDNSVVIVKDKK-GNPKGTLLKGPIAKEVVE-RWPAIAKIASVVV------ ------------------------MKKK-------------------------------- ---------------------------------LPTRGRTFVGTVVSNKMQRTVTVQWVR KRYMNKYERYELRRTKVKAHNPDTID--AKMGDRVKIMETRPISKTKHFIVIEV------ ----------LK------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFTFRGKELE--------------------ELKKLSIEEFATLL PARQRRSIQRGF------TDEKKKFLKKVAKK-D------------NVKTH-LRTMI--- ------VFPSM----------------------------VGKIIKIYNG--------KEF T-----------PVIIQEEMIGCF----------------------------FGE----- ----------LSLTR-RKVGHNA------------------------------------- -------------PGIGA-TK-------------------------------SSSNVSVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLASTDIDKINEVSEYIKNIAEKTGVVMKGPIPLPTKKLRIT TRKSPCGNGK-------ASWERYEMRVHKRLIDL-GIDERALRLVMRVQIPEGLNIEIEM IDE--------------------------------------------------------- -MKT--KFSPS-----WKSSVQPRKQRKYRKH-APLHLRSAF-LNVHLSKELRTKY---- ---------------------GKR-SMGIRQGDKVRIMKG--RFV--KTEGTVESVNLKK IKVYISKAEIQKKDGS-KTKYP----------LDPSNLLLLEAVMD-------------- ---------DKK-RS-----------------------------------KKLNKV---- ------------------------------------------------------------ --------KP-------------------------------------------------- --------------------------------MAKLKKAVCWRKL--------------- -E-RPYTRKSKFR---KKNFIRSV-PNSKIVKYDMGEL----NKTFEM-TYELRTKVPI- -QIRHNALESARQACNRWL-EKKIGKV-GFYFRVRVYPHHVLRENPLAA-GAGADRMSTG MAKSFGKTVGIAAQLRE-GQPIFEVMV---N-KQHELVAKEALHRAVHKI--PCSCTV-- ---------------------VK----VS------------------------------- ------------------------------------------------------------ -----------------------------M-TQN-DTLATTLSQIMNYERLGKRETMVKA NSALIRTVLTLLQNERYIGAFEIVPDGK-TGILKINL----------------------L GNINKIGVIKPRFSVSMAEYEKFEK--------------------RYLPAKDFGVLIVST SKGMMTHLEAKKMHLGGKLISYCY------------------------------------ MKLDKL------------EEKIKIPEHCTVAYADY-----QLTVK--GIKSEVVRKIH-S P-K----VQIHV-ENGF-VVFR---VN-KPS---KREKTLLFTYVAHVHNMFKGVTQG-H IYKLKVCSGHFPMSVSIK---NNV--FE-IKNFFGAKVPKHLTIS--KGVAVAVNGN--- ----DVTVESSDKELAGQTAASIERLTRRPG---FDKRI----------FQDGIYIVEKD GKAI-------------------------------------------------------- --------------------------------------MQFWPRKRAKRAYARVRSW-K- T-QK-----EVNLTGFAGYKAGMTHIMVQDTDKNSLTK--GMEVFVPVTVVECPPLRIVA VRFYKNG--I--------PAKDIVVSV-SKE-----L-----QKKT-------------- ----NLP---Q--------K-AHE-----------------------FSEVP-------- --------HDDVAVLVYTQP-----KMIGF-KKKPDVFEVKLSGTV-Q---EKLDFVKNN INK-DIKADSFFKEGAFFDTHVITKGKGFQGPVKRFGIDLRHH--KSEKTKRG--PGSL- GGWSEQGHVM-YRVAHAGQMGYHQRTTYNKQILKVSH---NPE--EVNPAGGFIHYGILR NPYVLVKGSVDGPKKRMILFTLPRR---I-T-VKKQARELP-TITHISTSSKQGR----- ------------------------------------------------------------ -----------------------------------------------------MNDQITA K----------------------------------------------------------- -----------VSGRDLS-ISRKTGIEICNHL--RNRTTKQAKSILEDAIALKRPIPHKR FTN-GLGHKR-----G----NLTS-GRYSIKACTELLNMIKSAESNAQDKGL-NINALKI VHFATQKASTPFHH------------GR--QTRRKTKR-SHVDLVV-------AEMSKDD -KKIEAKHEKSGEAESDKKPVI-------------------EKKVTVTPIEKTVPEK--- -----------TVSKEIKKTDAQKKNY-------EEERARL------------------- -----------------------------KKIVEEKRKQKE--------QEKK------- ----------LM------A----------------------------------------- ---------------------MGKNLIQQA-------------RGKGTPRYRAPSFNYF- GAAKI----NFKQE-----SAK----VVDLVFCRGHSAPLAKLQFPNKEE-GLIIASDGM KVGNIIYFGQ-------------HAQ---PLTGNTLLLKDIPEGSLVYNIEGIPGDGGRY VRASGGFAKVSIK-TE--N-QVMIIFPSKKQKTFHPLCKATMGIAAGGGRKEKPIMKAGN MYHRMRARNKRYPEISGSAQNAVDHPMG-NKRTSRK---S-K----AKPVSRNAPPGRKV GYIAARRTG-------QKK----------------------------------------- -------------------------------MN----------------------PMKAI RIEKMTLNVGAGKDQAKLNKGVILIKHL-TGI-EPVKTATQ--K--RIPSWGLRPGLPIG CKLTLRKD--V-DPLLKQLLGAKDNILKEDNFDECGNVSFGIHEYIDIPGVKYVPEIGVM GLQICITLQRP-GYRVKKRVLKKGAISKTHRINKQDAIQFMKERFALKL-EEEQ------ --- >GCA_008080745 -----MR-KRKS--KKINK-MRGRR--AAGYGFSAGHR-ASGQRGGKGM-AGSKKHHYIK VMQ-----EDPR--------------------------Y-F--G-------KH-GFKRPQ QLVE--ET--KI-----V-NVRDLDE----TIDELVE-KGLA-EK---------KGKTYT VD--MTRLD--FDKIL----GSGQITKKINLIGV---KSISRGAEEKITEAGG--SVE-- LLE--------------------------------------------------------- ---------------------------------------------------------MSA I--------------------KYFIEQNTRTLKI----------------DEFLTREL-N SAGYGGCEIR------KMPMRTEIVIHASRPGVVIGRRGSKIRELTYILETEFGIENVQV EVN-EIDNPWLSAQVM----------ASRLARQLER--GVRFRRMAYWVLRRVMRAGAIG CEIIVKGK-L------------SS-------------RRARYQKFK-------------- ----QGTIAKTGQPATTFVDESDDIAVLKPGVIG-------------------------- ----------IKVRIM---------------RPET----------KLPGVI--------- ------------------------T-V---------------KKPKPR-KEPQPTL---- ------------------------------------------------------------ ----------VKPP-----------EE--------------------------------- ----------------------EEEEAEAA------------------------EEDEV- -EETL--EGI--TD-----IDE-LRELEE----------LDGLEL-IEE----------- ---------EEEVAEESTEESNED----------------------------EE------ ----SAESAESVESDGG------------------------------------------- -----------------------------------E------E----------------- ---------------------------------------------MASVKTYSLKGKAGK AITLPTQFDT-PYRPDVIKRAVLSVQSYRRQPHGVDPLAGKKNTAQSWQTGH-------- ----GRSRMPR-IKG-SGTSAANKAAFAPGTVGGRTAHPPE-----ARKVIVERINKKER RLAIRSAIAATGDKDRVTERGHKVD--SV-PSLPLVVSDELETLSTTKAVREVV---TAL GLELDLMRAIKG-RRVRSGKGKMRGRKLKKPKSFLIV-V-G-SDQG-------------- -----IGLAARNLPGVDVTEVHGLNAELLAPGTHPGRLVIWTESA---IERLESENLFM- ------------------------------------------------------------ ---------------------------------------------MAQGPT---YRVKFR RRREGKTNYYRRRRLL-VSRRPRLVVRKTNRRVIVQIVNAKIIGDFTKSAADSREL-AAY GW----KGGTCNLPSAYLTGLLAGLRAKAN-GVDNAILDIGLHPPVKGSKIYAALKGAVD AGLDIPH--GDGVFPD------EDRLVGEHIVSSFKHLQDE---KESTMFSEIGK--KKT NITTLPKQFESVKKELEGLT-----KSQL-KKPKK------------------------- ---VEVTVP--------------------------------------------------- ---------------------------------EKT--KKKREKLEEKPPRAKPRKPK-- PKKLIAKGKGKRRKK-----MSR--KVGRG---IRKF-VPRIARGLPVGAKITCADNSGA KELQIIGVMG--YQGRLRRLAKAGIGDTVSVAVTKGKQELRKQ---VFIAIIVRQRKIFR RPDGTWMQFEDNAAVLVKPG--GEPQGSELRGPMAREVTL-KYPRVAAIASKIV---MAK DK---------------------QKVRNIG---IAGVNP-PEKI-----------C---- -D----DPNCPF------------------HGNLPVRGRLMEGIVTSTKMHKAITYQTDY IALVKKFMRYERRRTKKHAYLPSCID--VKAGDYVRVAECRPISKTISSVVIHV------ ----------TP----------------------------------------AEIKEE-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------MSRKGEPMYRGHKLE--------------------DLAKMNMDALIELL PSRRRRTLKRGL------PPRQKKLLMKLRAARKSQ-RKGKDA--V-VRTH-CRDMV--- ------ILPEM----------------------------VDLTVAVHNG--------REF I-----------RIKILPQMIGHV----------------------------LGE----- ----------FAITT-KTVKHGN------------------------------------- -------------PGIGA-TK-------------------------------SSQYVPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------TQRARIRLSSTSTEHLDGVCNQIKRITRKTGVRMSGPIPLPTRRMVIP TRKTPCGDGT-------ESWDKWEMRVHKRLIDI-DADERAIRQIMRVRIPDSVYIEIEL TG---------------------------------------------------------- --------MAK-----KPSSKSPRKQRRFLRK-SSIHEHKKL-LRCRLDEFLREEY---- ---------------------GLR-SLVARKGDLVRVMRG--QFR--DTEGKIVRIDYTK ALVYLDNASTTKADGK-EVQIP----------IHPSNLMLVKLELD-------------- ---------DD--RR-----------------------------------AIIEKKILEI ------------------------------------------------------------ --------AESE------------------------------------------------ --------------------------------MG-KRPGQCYRPA--------------- DR-PPYVR---------KKYIHRQ-PASRIVSFDMGNT----SGDFEV-VMSLIGLERC- -QIRHQALEAARVTCNRHL-TRRAGRR-NYHLRIRVKPYHYLRENKMIS-GAGADRVQDG MRKAFGKVIGVAARVNP-RQPLVTVRV---D-RQHIEVARTALKKAAAKL--PTPCKV-- ---------------------D-----FDEIDPELRRKLGYGYA---------------- ------------------------------------------------------------ -----------------------------M-TLL-DPLADAMSSIYNSELVGKPEVIIAP ASSLIERVLQVMQLKGYIGEFEQIDDGK-SGRFRIQL----------------------M GRTNKCGVIKPRYPVKRDGFERFEK--------------------RYLPAYNYGILIVTT PQGVMTHNDAKSRGIGGRLLAYVY------------------------------------ MSNKAVY-----------EKRIEIPEDCKVVLEGS-----KLTVS--GPLGTLERSFP-E P-Q----TRIEI-ENNE-VVAT---TF-ISR---KKTRALVGTIIAHLRNMFVGVTHG-Y TYEMKIVYSHFPITVEQR---GQE--VL-IKNFIGERGVRTARLI--GDVKLEITED--- ----DVIISGIDIEHVSQSAANIQLACKIRD---KDRRV----------FMDGIYVIRKR KGESVKSIV--------------------------------------------------- ------------------MA-------RRKKHAPRRGSLAYLPRGRASKFVPRIKNW-P- D-YEGD---PT-LLGFCGYKAGMTHAVITQTHESSPYK--GQEQVIPVTVIDTPPIRPFA IRGYETS--PYG-NR---VAVEVLAENLSED-----L-----RRAM-------------- ----PLP---KGY------DFDSK-----------------------MQEFEDR------ ---LD--TLVDIRVLVHTQP-----RLAGIAKKKPDIMEYKVGASTIQ---DAFEYAKNI LGS-DLRVADILEEGNLIDTIAVTKGHGFQGPVRRWGVRILQH--KSRKTKRG--VGCI- GPWS-PTNIR-YTVPRPGQTGYHTRTNFNNEVVKLGE---RGE--EITPAGGFVNYGVIR GDYVMLQGSVPGPVKRPVRLRFAIR---P-K-KGHT-GKAT-PVSYISTTSKQ------- ------------------------------------------------------------ ----MPSYRYSII---------------------------------------GIDPDRTA I----------------------------------------------------------- -----------ASGRNMR-CSPKFSREVCKAI--KGMMLDKAIDYLEAVIEEKAWVPYRR HKK-KRGHHS-----GMK--KWPS-GGHPVKPAQMILKIVRNAEANADNKGL-DIDRLRV MHAAAHRGRTYKAFIE-------RAFGR--SSPYFENT-THVEIVL-------EEVA--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGRRILVQR-------------KGRGSSQWRSPSHKKI- APARHP-K----WQPDKTYVGT----VANLYHESGRGAPLAEVRFEGEKRPHYMIAPEGI MIGQVVECGD-------------DAA---LANGNTLMLEYIPEGTPIYNVEGKPGDGGRF IRSSGLAGTIVTI-DE--K-VAIVRLPSGTLKRFSPRCRATIGIVAGGGRPDKPFLKAGD VWHHTRPKARKWPVVRGAAMAAVSHPHG-GGSHQSP---G-R----PTTVSRNAPPGRKV GNIAARRTG-------RKK----------------------------------------M SEIELPNADLYVQEW---------------EYS----------------------PMRKP KIEKVVVDMCTG-GGGVLERATTILEDL-TGQ-TPVVSRAK--Q--TVRDFGIRRREPIA VRVTLRDD-LA-EEFLKKALEAKDNILLFKNWDDDGNFAFGISEHIDIPDVKYDPQLGIQ GMNITVCVERP-GFRVKRRRRRRQKVPWRHRMTPEESMVFIKEKFGIEI-LEKERERTYL F-- >GCA_016932735 ---------MAS--KRVNR-FRGSR--THGCGSHKKRR-GAGSRGGRGM-TGAKAHRFVK FLK-----EKPG--------------------------H-I--G-------KY-GFTS-- HVSQ--NL--KT-----I-NLCELER----LADRL----GIK-----------------E VK--LKEMG--YDKLL----GKGKLSRPF-TVHV---DFISSKAREKVETAGG--KAI-- VPEPEP----------------------EKTKPAEEEAQTDE------------------ ----------------------------------------------------------MI DI----------------LLNRHFVNQSINGLKM----------------QEFIEEYL-K GEIFSDIELE------RTPLGLRIIISTSRPGRIIGAGGRKINGLADEIKRRFNVENPQV DVK-TIKNPDMDARLV----------AKQIAFALET--GNKHKKVGNLFMKRVMDAGALG VQIVIGGK-L------------GG-------------SKGRTDKFA-------------- ----RGYIKYCGDTAKTLVDHGFAEALTRPGKIG-------------------------- ----------VQVKIMK----------------------------YFMDTF--------- -----------------------GN-I-----------MTKKDIMDAKAAAIQEVIE--- ------------------------------------------------------------ --------AKKETD----------YEEEAEDI---------------------------- ---------------------------DNLDD---------------------------- ------------------------------------------------------------ ------------EIDDDEEKPKKRKVVV-------------------------------- ---PKKEKKKQTEK---------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MQVSVFDLKGAEKG KIEVPKKLLA-PKRKDIVKKAFLAEKSETRQPYGTDPEAGQRSSAYYHGRRS-K-R--NS MMNREMARMPR-VIN--MGFLNFRARNVPQAVKGRKAHPPK-----AEKVWTLKINKKEW TSALYSAMSFTFDKNAVSLRGHDVS--SL-KSYPLVLDDSFQEMKKTKEVVDVL---NVL GFEKELERCSE--KKIRATKGKMRGRKYKEKKGPLII-V-N-EDKG-------------- -----IGNASKNIPGVDFRMAGKLDVMSLAPGAHPGRLVIWTKSA---LESFNKTKEDKK EKAVKVK---------------------------KAVSPKA-DAPKKK------------ TSAKEKAK--------------------------------------MPRGR---KIVPHR RVREGKTDYRQRLKLV-KSGKPRLVVRRANRNMSCQIVSFDKKSDKTLVSASSIEL-ANF GW----NANTGNIPGAYLTGLLCAVRAKSA-GIKEAVPDIGFFEAHHGSRVLSALKGALD GGLEIPH--SKEAFPP------EDRMNGAHIANYAAELKKGDNAKYEKYFSAYIK--AKV DPETIAKLFETVKSKVISEGASEKKPKPVTQKKEK------------------------- ------------------------------------------------------------ ------------------------------------------------------------ KATPKKEPEKE----------------------MKAI-PSSVTQSLTTRSVIRCADNSGA KWLEVIAVKG--FRGRRRMKPSCGVGSFVFCKVRSGNEKVRHQ---VLKAVIIRQTKEYR RSEGLRISFEDNAAVIISDK--GEATGSIIKGPVAREAVQ-RFPTIGKIASIVV------ ------------------------MKENLG---LG-LN-PPKEK-----------C---- -E----DHKCPW------------------HGSLSVRGKILEGVVKSTKTHKTATVEWKY IKFVRKYERYERRKSSVAAYNPDCMN--AKEGDSVVIVECRALSKTKHFVIVHV------ ----------DK---------------------------------------------AKA DK---------------------------------------------------------- ------------------M----------------------------------------- ------------------------------------------------------------ ------------VMVKKFMFRGKEWE--------------------DISKMGIEEYSKIV TSRERRTLKRGL------TIVQKKLLEKIKEKPKKF-----------HKTH-SRDMV--- ------ILPQM----------------------------VGVKIGLFDG--------KKY E-----------TIEIKPEMINHR----------------------------LGE----- ----------FALTR-KQIKHSS------------------------------------- -------------PGFGA-TK-------------------------------SSKFVPLK ------------------------------------------------------------ ------------------------------------------------------------ ------------MEYARIKLAGRDHKKLEEICKEIQEIAKKYGTTIKGPIPLPTKKLKVT TLKTPCGDGTGH---GNATFDKWEMRIHRRVVDI-GANERALRQVVRIQIPADVKIDIEM KERYEHK----------------------------------------------------- -MKK--SWSNE-----WVSSVQPRKQRKYVHN-APLHVKHRL-LSVHLAPVLRERY---- ---------------------GTR-SVTVRKGDKVKVMRG--SSK--GFSGPVERISLKK MEVFIEGLKAKKVDGT-EVLKS----------LKPSNIMITELNTD-------------- ---------DKT-RQS----------------------------------KLLGKEKT-- ----PAKPKGGAVKKAGSE------AKKAESSKE---------EKP-----------KES KAPVKKEAAEKKVASPKKSVASKKPAETKVKK---------------------------- --------------------------------MATLRPARCYRTI--------------- -K-RANTRQSQRKP--KKGYVKGV-PYPKIHRYTFGDK----KTDYRL-SMYLRVDNAV- -SIRHNALEAARVALNKAM-TKNVGDG-FYMMKVLVFPHHVMRENPLAT-GAGADRFSTG MRKSFGKPIGLAAMVKK-DQRILQIKL---N-PDKEAAGKKALKVASSKI--PSTCRI-- ---------------------E-----SVLTK---------------------------- ------------------------------------------------------------ -------------------------------MKH-DSLSDMFTILMNTETVGKISCIV-P SSKVIKEILKTMQKKGYIGNFELIDDGK-GGKFRVEM----------------------V GKINKCGVIKPRHAVGLRSFINWEK--------------------RYLPAIGMGELFVST PGGVMSHRDATEQKSGGVLLGYIY------------------------------------ -----ML-----------KTGYEFPEGVTATLEDT-----EIVVK--GPRGELKEKMS-H P-K----IDLKV-DKNV-MIVT---SE-DEN---KRTKAVMWTWKALAKSMTIGVTEG-W QCDLKLVYSHFPVKLKQE---GSK--LI-IENFLGEREKKEVTIP--SEVKLEINGN--- ----DLKVTGNDKEKVGQAAALIEQRVTVKK---FDRRV----------FQDGIYKIGKT HTLET------------------------------------------------------- ---------------------------MAHGHKPKAGSRAFWPRKRAKRIYPRVTSA-S- V-PKLKG--DVKPLNFAAYKAGMTTVIHEGNRKDAPTF--GKDMARPVTVLDCPPLFVCG AKLYGRN--ESD-AV---SLGMVFAEKLDKS-----L-----SRRI-------------- ----SLP---NKY------DFKKK-----------------------LADAEKL------ ---LT--EADDVKLVVSTQP-----AKGGIGKKTPEIFELTL-SGEKD---AKWAYAKEN LGK-EIKVESVFEEGEFIDTTSVTTGYGMEGPVRRFGVKVRNR--KAHNKRRH--VGNI- GAVT-PSRVLPGKIAMAGQHGFQTRTEYNKRIFKIAS---DG----FEPSGGILNYGSVP GQYVLLHGSVGGPKKRLIMLRKAMR-------RTGE-KIPV-EIKHVSKESQQ------- ------------------------------------------------------------ ------MLKYALN----------------------------------------LNPKKSA R----------------------------------------------------------- -----------AYGRGLS-ISPKHSKILCGKL--SGMNLQKGIKLLNGLSTETVSID--- -------------------------GKHYTTAASNILDLVRSAEKNAEFKGL-DTEKLVI M-ASAHEAFSFFRP------------RRTKMRRQQRKS-TNVQVVL--R---VS------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRIIPQR-------------RGKGSLTYRVPNKSSN- VRVEY-----------RPSSGR----VVDILSDPLKTSPVAKVRYDDNST-GFILAPQGI RVGEEIGK-------------------------YVVPLSMVPEGATIFAIETVPKSGPKI CRSAGSFAMLVSK-AG--D-DCIIQLPSRKKKKLKGACMVTIGVPAGEGRIAKPWLKAGK RWIVQHKKGKLYPRTSGIAMNAVDHPYGCGYGG-----LG-K----QKTVSRHTPPGRKV GSIAARRTG-------RTKK---------------------------------------- --------------------------------------------------------MREI RIEKVTINVGTKEDADVLNRAVFMIKKI-TGK-DGVITTTH--K--R-TTFGGAKNRKIG CKITLRGD-EA-KEFLLNALKAVDNRIKPTQFDRTGNFAFGVKEYINMPGMKYDPDIGIL GFDVIVTLKRP-GFRVKKRKLKAAKVGKKHLIPPEESIEWAKKELNINV-TEEVEEKW-- --- >Bin210_genes -----MP-VNKS--KKFGK-YRGHT--THGGGHRKKRR-GAGSRGGRGN-AGTGKRAGQK K---------AG-------------------MA-----PKL--GV-----LTS-GFTPR- -GREFKSK--QS-----I-NLSELSSI---KLDLWVA-EKKA-TK---------QGDAYV VD--LTKLG--YQKLL----GTGSINLKL-QVTV---NKVSKLALEKLEKAGG--KVV-- I-------------------------VEAEVSSEAAPKVTEEKP---------AKPSEKA EA--------------------------------------------------------MI E--------------------RDFITQKTKEYYI----------------KSYIESKL-R GAEISEIKLK------KIPLGEKIIIRTSRPSLIVGSKGANIRKLTTYLKSHFKLENPQI EIK-EVKNIFLDANVM----------ANRIVSSLERFGSARFKGIGHKTMANILSAGALG VEIKISGK-I------------PG-------------ARAKNWRFY-------------- ----QGYLKKCGDVSVSGVKTAYASALLKTGIIG-------------------------- ----------IQVRIM---------------PPDL----------ILPDSV--------- ------------------------E-I------------L-DEIVQV--AESTDVEEEK- ---------------------------TEDKK---------------------------- ------KATKKKVAKKKTTTKKTPAKKKETKK---------------------------- ---------------------------KTVKKEET------------VKEEAPAEEKPVK KEETVKEE---------------------------------------------------- ----------APAEEKLVKKEEPKAEVEPKTEEVE------------------------- ---KVKEESKVEEKLA-EETQEN------------------------------------- --------------------------------PDQEV----TEKKSV------------- EETKEE----------------------------------------MELKVYDLEKKSTG AVKLPSQFEE-EYHPDLITRAVHALQSKARQTYGASPDAGMRHSSKLSKRRR-K---YRG CYGFGISRVNRKILSRRGTRFFWVGAFSPQTTGGRRSHPPK-----AEKNWIKKINKKEN QKAIRSAMAATLNKSLVEERGHKVP--V---EYPLILKSDFENLQKTKDVKKVL---ESL GFNAEIERASV--VKVRAGIGKRRGRKYRKRKGVLLV-V-S-GDCP-------------- -----VMKSARNFAGFDIVPINQLNAELLAPGAMAGRATLWTEGA---IAILESKKYFA- ------------------------------------------------------------ ---------------------------------------------MASKKA---RPVLYR RKREGKTNYKKRLRLL-LSDKPRLVLRISNTKIDAQIIKFDVKGDLALLGVGSTSL-KNN GW----LYSTKNLPAAYLTGLKVAQMAKGKFDSEGLVLDTGLRTPLQKGKVYAFLKGALD GGLNVAHGSEEKIFPT------NEKISGKDIQDYANNLKQENAELYQKKFSANLK--NGG DPTQMVANFEKVKAEL------------MKH----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAV-KARVHRALPSQAVVNTCDNSGA KIIKIVSVKG--HKTVKGRYPAAGVGDLVMASVKKGKLDMRKT---VVPAVIVRQRKEYR RPNGTRIKFEDNAAVVLKDLK-GNPKGTLIKGAIAKEVVE-RWPAIAKIAKIVV------ -----------------------MKTELLG------VKI-PEKK-----------A---- -DEN--DQNCPF------------------HGSLNVKKETFTGVVVKKDAHGTATIEWFR QILVPKYERSEVRKSRMRAHNPPCIN--AEVGQKVLVARTRPISKSKHHVIIQVLGTEKI IESE-DIT--LKKKAKKS---NKVEEVKAEPVKQEEVQEEI---QETPEQEEVQEVAEEQ SEESTE------------------ENKEE------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------MAKELKWRGLSEE--------------------EAKNLEMSKFLEMI PARRRRTLKRGY------TDDQKALLKKLEKNES------------NIKTH-SRDMV--- ------ILPSM----------------------------VGKTIGVYTG--------KEY V-----------PVIITIEMLSHC----------------------------LGE----- ----------YAHTR-KSVSHSS------------------------------------- -------------AGVGA-TR-------------------------------SSKAVTAR ------------------------------------------------------------ ----------------------------------------------------------M- ------------GQKARIKLASTEIDKINRVCSSIREITEKTGVKMRGPIPLPTKKLKVT SRRSPDGEGR-------ASWERYEMRIHKRLIDI-GTDERTLRLVMRVPIPEGLNIEIEM VDA--------------------------------------------------------- -MKN--------------KSVQARKQRKARYG-AVLHQQQKF-MHVHLSPELRTKY---- ---------------------GKR-NIQLRKDDKVKILRG--NFK--KKEATVERVDLKR EKVYLGGIETIKKDGS-KVAYP----------LKASNLMIITLNLS-------------- ---------DKK-RK-----------------------------------AKLEGKKE-- ----VKSKVESAAKP--------------------------------------------- --------AEKSA----------------------------------------------- --------------------------------MARIRKFVAYQGL--------------- -E-RPYTRISKYN---KKNFVRGGFPHMKVIKFDLGNK----NGVFDS-MVRLVSTRAM- -NIRHNALESARLTSNRYL-EGRL-PK-NYHLKIKVYPYHILRENPLAS-GAGADRMSTG MKKSFGKIIGSAARVKI-GQTLMEVRI---D-KANIKIAKEALSRAGKKM--PCSCRV-- ---------------------N-----VIETSTK-------------------------- ------------------------------------------------------------ -------------------------------MLN-DPLAMALTKISNAERVGKKEVVLKP VSKIIKKILTIMNEHNYVGVFEEEVHDS-GITVKVNL----------------------L GNINKCNVIKPRFSTKLSNFTKWEK--------------------RYLPARDFGIILVST PQGIMTHEEAKKKNIGGKLLAYCY------------------------------------ -MKENL------------KKEIELPEGVTASLTGK-----TLAVK--GPKGENQRDFA-H P-S----IEVVV-EGNK-ILLN---AV-NAT---KREKKMLGTYTAHIKNLVKGVQEK-F EYKLKICSGHFPMNVSVS---GNK--FI-IKNFLGEKHPREIMFP--QEVEVKVNGE--- ----IIEVKSCSRELSGQIVGRIEQMCRITD---KDIRI----------FQDGVYIIKKP RYSD-------------------------------------------------------- ---------------------------MGKARSPRRGSMQFWPRKRSKHSFVRVRSW-A- Q-QN-----KAKLLGFIAYKAGMTQAIVLDNRANSMTN--GEKIAVPVTVFDCPPIHVLG VSFYKTS--GRG-AQ---KVAFAFSPEISKD-----VKK-IASKRI-------------- ----SLP---K--------KEAAS-----------------------LDEVK-------- -------DYDYLKLLVMSNP-----SLTTTGTKKPKFLEMGVGGN-KE---DQLNYAKET IGK-ELKIEDVFNAGGLVDAHAVTKGKGFQGTVKRYGVAIMQH--KAEKCIRG--IANM- GAWT-PKRVD-YRVAQPGKMGCHLRTEYNKVVVKLGD---NPE--DVNPKSGWKNYGLVR NNYIMLRGSIAGPRNGAVLLSEAIR---P-N-KKLQ-KEMG-EV--LTILK--------- ----------------------------------------------------------MA KPKVEKKENKTVK---------------------------------------KDVSGHMA K----------------------------------------------------------- -----------ASAMSLH-ISTKQAIEICDSI--RYKTTKQARELLENVVSFKKALPFKK FNR-DMGHKP-----G----RVAA-GRYPQKAATEFLKLLKSIEANAQVIGL-DTANLKI QKVLANKAATPMTG------------GR--QR-RGTKR-THIEMEV-------IEGKGPK --RKEAKKAKLVKKETKVKEPV------------------KEIKAEKKVEEQQVTE---- --------TKVEEKEVVKKEEETPKPE-----PVKEDKPV-------------------- -----------------------------------KNEQKPQ-------EEKK------- ------------------VEQKND------------------------------------ ---------------------MGKRIIQQR-------------RGRGTGPYRSPGHRFK- GPAKH-----LPYEA----EGV----VVDIINCPGHDAPLMAVSYDSGEV-ALTQAPNGI KVGDLIKVNA-------------DT----LEKGNVVALKDIPEGTLVYNVEARPGDGGKF VRSSGAFAKVVAK-TE--K-GIRIKLPSKKEKNFLPECRAAIGVISGAGRTEKPLLKAGT QFHKMKARNKLYPKVCGISMNAVDHPFG-GGCSHVK---G-R----PTQSRRGAPPGRKV GKIAPRRTG-------RRKGK----------------------------MSEENQTTPKT EVKEKAPVS-------------------TSKDN----------------------PMKEI KITKITLNIGSGKDQDLLKKGLKLLKKL-SPL-TPVKTTAK--K--RIPTWGLRVGLPIA CKVTVR-K-DA-EKLLKRLLVARDNTLPNKSFADNGNFSFGVPEYIDIEGLEYDPDLKIM GLEVAVTLERP-GFRIKNRKVTPRKVGKNHLIGKEESIKFMENKFGITV-E--------- --- >GCA_002690055 -----MT-VNKR--KKVSR-YRGSM--THGGGSKKKRR-GAGNRGGKGM-AGSGKRGDSK K---------PSLW-K---------------QK-----Y-F--G-------KY-GFTSK- NTGN---I--NA-----T-NIDYLEE----NLLKL-P-QDVV-SK---------ENEFFS VD--LKKLG--FNKLL----SKGKVINKY-KIRV---TYASKKAIEKIKNNGG--EVI-- L---------------------------------LK------------------------ ----------------------------------------------------------MI E--------------------RKFIAQKTKEYQI----------------QEYINENL-K NVGHSHTKMV------KTPLGEKIVLYASRPGLIVGRKGQNIKELTKTLKKRFGLENPQI EIS-EVTDINLDANIV----------AERIANSLERFGTQKFKAIGHRVMEDVISAGALG IEITVSGK-I------------PS-------------SRAKSWRFY-------------- ----SGYLKKCGNIAIVDVDKAYVQAKLKTGVVG-------------------------- ----------IKVSLM---------------PPGI----------KLPDKV--------- ------------------------E-L------------I-EEKEEK--I---------- ------------------------------------------------------------ ----------EEVS-----------EENKEGK---------------------------- ---------------------------NEIKP---------------------KAKKTAK TNARTKSN---------------------------------------------------- -----------AVEKEAEDKNPDE------------------------------------ -----EKAEKESVVKPHKEPAPN------------------------------------- --------------------------------VHD-------GVKNE------------- D---------------------------------------------MKLDILDISKKKTG EINLPIQFNE-DVRTDLVSRAFLALRSNNRKPYGAKTEAGKRSSSIISKRRH-Q---YRG SYGFGISRTPRKILSRRGTRMNWVGAFAPNTVGGRRAHPPK-----AEKILVKXLNKKER KKAIRAAISATIIANRVKSRGHIIP--E---NYPFVLNKKFEELVKTKEVLSSL---KSL GFEKELERVGE--KNVRSGKGKTRGRKYKTKIGPLIV-T-S-KESS-------------- -----ITKAASNIPGIDIVNVKNLNIELLAPGEFSGRLTLWTMGA---IETLEKEKMFR- ------------------------------------------------------------ ---------------------------------------------MEKTNI---YTMQFR RKRKGLTNYRKRLKVL-AAKRPRLVVRRSLKNIQAAIVGYDKKGDIVKASSHSSNL-KKF GW----VYGTGNLPSAYLVGFLLGKRI-NP-KFDEVILDIGLHKSVSGSRIYAVLAGILD AGLKVPH--SKEVLPS------KERVMGKHIMDYAELIKKDTG-LFKKQFNSYSKKGHTF DL---VKKFEQVKDNI------------NKQQDK-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MQAV-KSRVTKAIPVGSQIETCDNSGA KVIKIFTVVG--RKTTKGKVPAAGIADLVTASVRRGRPDMRKQ---VIYAIIVRQKKEYR RADGTXIRFEDNSAVVLKDDK-GNPKGTIFKGAIAKEVCE-RWPGIAKIASIVV---MVK ---------------------TKMEVKNMG---IK-VER-PKGK-----------C---- -N----DSNCPF------------------HGSLKCRGRIFTGTIILTNMQKTATVEWEH RYFLRKYERYEKRRSRVKAHNPGCLN--AQDGDIVKITECRPLSKTKNFVIVGI------ ----------LG-KEKGF---KEKMEAQEESKVK-------------KEVKKAE---EQT DGA---------------------E--EEVTA---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFSYRGKTLE--------------------ELKGLSLNEVAALL PARQRRVLKRGL------TDQQKILLKKIKKNEG------------NIETQ-CRDMI--- ------ILPEM----------------------------VGKTIRVHRG--------KEF L-----------PVIIIEEMIGHY----------------------------LGE----- ----------FVLTR-XRVEHSA------------------------------------- -------------XGIGA-TK-------------------------------SSAALSVK ------------------------------------------------------------ ----------------------------------------------------???????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- -MKT--KFSSS-----WKKSIQPRKQRKYRHK-APLHIRQKF-VSVHLSKELRKKY---- ---------------------NKR-SMNLRKGDGVNVMRG--QFR--KKTGKINGIDIKK TKVYVDGIEVVKKDGT-KARYP----------IHPSNLVITELNMD-------------- ---------DKM-RN-----------------------------------KIVKRV---- ------------------------------------------------------------ --------EGN------------------------------------------------- --------------------------------MARIRKFVSYRRI--------------- -E-RPYTRTSKYK---GKSYIKIS-PNIKVIGFELGSP----KKSFQY-TLKLVSKDNL- -QIRDNAMESAKQTSNKIL-ETSLGLS-GYHLKVKPYPYHVLRENPLAS-GAGADRFSTG MQKSFGKPLGNAAQIRT-GDSIFHISV---D-KANLELAKTALTRASKKL--PCSCMI-- ---------------------Q-----VTENR---------------------------- ------------------------------------------------------------ -----------------------------M-SLN-DPLANALSLILTDEGAGKKESKIMP SSKIVEKVLDVMKNNNYVGDFEEIKGRG-GNSIKLNL----------------------L GNINKCGVIKPRYSVKKGDFERFEE--------------------RYLLARGMGILIIST PLGIITHKESKKKNMGGKLLAYCY-----------MANK--------------------K SK-TNL------------SIEIKLPPEVNAQLDKD-----ILTLK--GPKGDAKRNLS-D K-K----VSIEL-KEGS-VILK---AL-KSN---KVNKKLIKSYAAHIKNMIKGSFDG-H KYTLKICSGHFPMNVSIN---KDQ--LI-VKNFLGEKVPRTLKLK--PSVEVKVEGE--- ----LIIVESSSKEIAGQVSSDIEQLTRRTR---YDTRI----------FQDGIWVTSKD DK---------------------------------------------------------- ---------------------------MPQKRTPRKGSLQYWPRKRSKRSFVRVRTW-A- K-TK-----EVKLLGFAGYKVGMTHLIINDNKKTSTTK--GMDIFCPVTIIXCPPLKTAS IKFYKNT--ISG-SK---LVSEVLAENFDKQ-----L-----KRSI-------------- ----ILP---K--------K-GSK-----------------------GARTKDAANSVGN KSFPS--DFDYITLLVHTMP-----SLTGLGKKKPEIFEMGIGGNK-E---DQLNYAKNK LGN-EINISEVFKEGQQLEIHAVSKGKGVQGPVRRFGISLKHH--KTEKSRRN--PGSL- GGWIAQGHIM-WRQAKAGKMGYHARMEYNKWLLKIG----NPN--EINKKGGFENYGVVK NAYILIKGSVIGPKKRLIRFNDSLR---R-D-TTLP-NESP-PMQYINLEQKSR------ ------------------------------------------------------------ -----MANIYSTK---------------------------------------DYNKENMA R----------------------------------------------------------- -----------ALGISLP-ISFKQSIEICNFI--RNKDVIYAKRVLSEVIDHKSAIPFKR FNK-GVGHKK-----R-----ISA-GRYPKKASMGILNLINHVEANAQFKGL-NTANLVI IHINANKASKVMHF------------GR--KRSREAKR-TNIEITV-------QEK---- ------------------------------------------------RVDKK------- ----------------------------------SEDKE--------------------- -------------------------------------------------KAVKGIKK--- ------------------------------------------------------------ ---------------------MGKNLIQQA-------------RGKGGPRYRAPSFRYK- GKSKY-----GNYERE-TLNGK----IINLIHCQGHSAPLAQXEYTNGNV-XLMQAPEGV RIGDKVETGV-------------NVD---IKKCNMLPLKSIPEGIDIYNIESFPGDGGKF VKSSGGSAKIITK-MQ--N-RVVVELPSAKRRDFLPDCRATIGIVAGSGRKEKPFLKAGK RYYAMKAKNKLWPQVSGSSMNSVDHPFG-GSSSASK---S-G----PTQASRXAPPGRKV GKIAPKKTG-------KKR----------------------------------------- ------------------------------------------------------------ --------------------------------------------------------MPIG CKLTLRKK-EA-LELLKRLFEAKDNTLQVSNLDNEGNISFGINEYIDIPGVKYDPDIGIM GLQVCITLKRS-GFRVKSRALKRHAIPRKHRVKREEAIDFMKNMFNLKV--GE------- --- >GCA_011605725 --------------------MRGSR--THGWGQVGQHR-KSGSRGGVGR-AGSMGHKFLM FYK-----EEKE--------------------------KGF--V-------RK-VPR--- --VE------GGK----I-NVGKLDE----LYRRMHG------RA---------PEGGEI LD--LAALG--YSKLL----GSGSVSTAY-VVKI---ASFSEKARMKIEAKGG--RIV-- KPGEA------------------------------------------------------- -------------------------MKPLLTWRP-------------------WLWRRLV EM----SAR------RKTIFYKRVLEFGKLHQKI----------------DDFLKEYL-K EAGYNGVRLL------NVPMGLVVTIYTSKPGAVIGPDGRNIRELQNMLQKNFGLENPQV NVA-EVENPDLEPQLV----------AQMICRALER--GVKYRRAARVALRRIVAAGAVG CEIRIAGK-L------------AT-------------DRSRFEKFT-------------- ----YGYLPAAGDPAMKYVKTGKASVLLPQGLIG-------------------------- ----------VKVKIL--------------------------CKASFPDEV--------- ------------------------QII--------------------------------- ------------------------------------------------------------ -------GVQKEAA---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---EVGEAKGE------------------------------------------------- ------------------------------------------------------------ ---------------------------------------MMSMQEEVKIRVLKADGEEDG EASLPSFITMFEVEDFLIRRAFLAQQSRRLQPQGRDPMAGKRTTAESWG----------- -VGYGIARVPRTERG--------VARFAPMTVKGRVTHPPR-----VEKKIRKEINRKEY RKAFVSALSAVFKKEVVEKRGHRPG--SA--SIPIVFTKEFENISKTRELLKLL---EKI GLEQELERIYGR-PRVRCGKSKWRGRRLRRRIGPLII-V-SNNKAS-------------- -----VVKAASGIPGVDVRTPEKLSVMDLAPGGAPGRLTIWTLPA---LENIVEK----- ---------------------------------VRKYVSK-------------------- ---------------------------------------------MARSAS---YRVKFK RRRKGLTDYYLRTKLL-RSGLPRVVVRVSNKHVRVAVVSSRLGGDVVIAHAFSQEL-KKF GW----PFSFNNTPAAYLTAYLAGLRCLKK-NVSEGILDAGLHKPTKGGRVYAACSGLLD AGFKLRV--DPSMLPD------KSRITGEHISRFFKE-------SGGKGFSRYVE--AGL KVEEMPKIFEEVKGRLREAA--------VNG----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------MAVKKSR-AVSAKG---ILEY-RLRGSRGLPVGASLVCADNSGA KLLRIVQVAK--SGGRLRRLPSAKVGDLVTVSVKKGTPDLKNK---LMKAIIVRQRFPIR RRDGLRVVFEDNAAVLMTPE--GDLKGTEVKGPVAKEAVD-LWPKLSALASSVV------ ------------------------MSFLKG---LN-ISP-PETE-----------C---- -S----DRKCPF------------------HGEVRIRGSVFEGVVVSDRMKNTVIVMREY LQYVPKYKRYMRKRSRIPSHNPPCIA--ARTGDKVIIGESRPLSKTVHFVVLGK------ ----------VK------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MSIVQTYRGKTLE--------------------ELNSLSMNELMRLL PARIRRSLKRGL------HPETRKLLEKIRKVKAEMARTGVQP--RRIRTH-RRDMP--- ------ILPEM----------------------------VGLTIEVHNG--------KDF I-----------PVEITLDKVGHY----------------------------LGE----- ----------FAITN-KRVVHGK------------------------------------- -------------PGVGA-SK-------------------------------ASTYVPLK ------------------------------------------------------------ ------------------------------------------------------------ -----------------MKIVSNELSDLQTVVDQILKIAKENNVKVSGPIPLPRKVLKVT TQKNPSGQGT-------ITWDKFEMRFYRRLIYL-GLNDKALRALTTIRIPQSVIITLDL IS---------------------------------------------------------- -MNER-------------------------------HLAYKA-SSVHLSRELRSKY---- ---------------------GFR-SLPIRAGDRVLIIRG--DYK--GVEGDVSRVDRAR GRVYVSGVYRENARGE-QRLIP----------IPLSSVILVKIEDK-------------- ---------DEW-RR-----------------------------------RLIERKLK-- ------------------------------------------------------------ -----PVKEASENGS--------------------------------------------- --------------------------------MK-------------------------- -Q-MPYTR---------KEYISRI-PQVRVSKFKLGR-----AEDFEA-VFRLRVKKPS- -LIKQEALEAARVAANKIL-EAELGET-GYVLRLIPYPHIVLREHKMLT-MAGADRLSKG MKKAYGKPTTLAAKIEA-GEPVMEVFT---S-LQHENTVKKSLKTASSKL--PVETFIE- ------------------KEVVKKGGEVDEGES--------------------------- ------------------------------------------------------------ -----------------------------M-TLN-DPLANALTALQNADLRRKKECIISP ASNLIGHVLKILQQSGYIGEFEFIDDGK-AGFFRVQL----------------------V GRINKCRAIKPRFPASYRDIEKFEK--------------------MFLPAYNVGLLIVST PQGLMTHTEAKSRKIGGRLIAYVY------------------------------------ -MESAVH-----------VATVKVPENVKISLQYS-----TVTVE--GPLGRLSRDFS-H T-G----LKLTL-EGDV-LKVF---SV-NKG---RRFKARVGTVAKLIKNMFEGVLHG-Y IVRLKIVYSHFPVTVKYDKPTGTVS----IHNFMGEKSPRLFKIPF-PNVDIHVSGQ--- ----DITVTGLDKNEVTQVAAMFELATKIKD---KDPRV----------YIDGIYVVEKG LWRK-------------------------------------------------------- ------------------MG-------HRKQSAPRHGSLAFRPRARFKRLTPRIRFW-P- E-VDG----ETRLLGFAGYRVGMTHGFTIDTSESSPFK--GKEVFTPITIIETPPLSIVG VRLYGNS--PQG-LR---VIWEGWAKNLPEN-----L-----KRRI-------------- ---NTLG---K--------SEEAA----------------------EPRAPEGI------ ---AE--KTREVRVIVATQP-----HLAGLGKKTPEVFEIGVGGGSMS---ERISYAMSL LGR-EVYAKNVLEEGAYVDVFAVTKGKGFQGVVKRFRVKILDR--KSNKTRRG--IATL- GPWK-PAGVM-YTVPRPGQTGYMQRMVRNLQVLKIVE---NPG--EINPAGGFHKYGVIK SQAVILNGSVPGTPKRLVKIRVSAR-----K-HDVKPKQPP-VLTYVNIRRPVAV----- ------------------------------------------------------------ ----MPSFKYSLV---------------------------------------EVDRARSA K----------------------------------------------------------- -----------ASLREVR-VSPKHSVELARFI--KGLRIPEARERLEAVVEKKLPVPFKR YRK-KVPHRR-----GVL--KADS-GRYPVKAARFLLRLLAQLEANAEFKGL-SPERMRI TGVVVHRGRKLKRYTP-------RAFGR--ATPRFETL-THVEALA-------VEEAG-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRPIVRR-------------RG-ASPNFMAPTHRRV- APAKY-----PTLAKGERLEGT----LVALHHDPGRGAPLAEIRLDNGKT-FYTVAVESM YVGQRISIGP-------------GSP---LAVGNIIPLSEAPEGIMLSNIERKPSDGGAL FRASGNYAVLIGK-TN--G-TAILQDPKARTFIVDANSLGTIGVIAGGGRTEKPFLKAGT KRKLMKSKGRHYPIVRGVAMISVYHKFG-GGRHQHV---G-G----PSSVSRNAPPGAKV GLIAPRKTG-------RKKARRVSG----------------------------------- ----MVETVLEEKKA---------------QAN----------------------PMRRI MIEKVVVNICPGKPGEPLEKAKQVLTLL-TGM-KPAERRAR--K--TIKEFGVRRREAIA AIVTLRGS-RA-EEFLEKAFTAIGRKVKASSFQN-GVFSFGVREHIQFPGVKYDPKIGVL GMDICVKLCRP-GFRVMYRRRRRSTVGKSHRITREEAINFMKERFSLEV-V--------- --- >Bin185_genes ------------MAGKNVQ-KAKLI-------------------------EDLRRLGTKE K---------VAFWKR------------------------L----------AN-DLSKPT RNEI------------KV-NLHKINKF----------------FK---------KDEIIV VP----------GKVL----ATGDLNQKV-TVAA---YNCSEVAKEKIQK-SG--KFM-N LRELMKT------------------------NPKAKKVRILA------------------ ---------------------------------------------------------KMI E--------------------RKFVAENVRLFQV----------------KTFVIQKL-G LGKIGDFEIK------KTPLGEKIIIYTARPGLVVGRKGENIRELTKVLKSKFRMENPQI EVS-EIERPDLDAQTV----------AEQIVNVLERFGPKRFKATGYRTLQRIIDAGALG AEIVISGRGL------------PS-------------TRAKTWRFY-------------- ----AGYLKKSGDIAMNHVRKGLAVANLKSGSVG-------------------------- ----------IKVSIL---------------TKDV----------ILPDTV--------- ------------------------D-I------------H-EIAEKTE-IKVEEVKEEE- ------------------------------------------------------------ --------KKEEVK-----------EEKKEE----------------------------- ------------------------------------------------------KKKPVK ------------------------------------------------------------ ----------------KTKK---------------------------------------- -----KAPKKMED----------------------------------------------- ----------------------------------KK------EDKK-------------- ----------------------------------------------MKANLVDLTGKKVK EIELPSQFDS-DYRPDLIKRAVLAIQSHLRQAYGSKEGAGMRHSAELSRRRR-K---YRG SYGHGISRVPRKIMTRRGTQFNWTGALAPGTVGGRRAHPPK-----AEKKYAQKINITER RYAIRSAIAATVDKKLVAKRGHAVP--D---IYPFVIDAKFEAVKKTAEAKKVL---SAL GLDKELERASI--KKVRAGKGKNRSRRYKKRTGPLII-V-S-KKCD-------------- -----LNKSLLNVPGIDIITVDSINTELLAPGTTPGRLTLWTQNA---IEKLDKEKLFTN VK----------------------------VPHAKIEDKK-------------------- ---------------------------------------------MIRRKH-----VAFR RKREQKTDYKKRLGLV-KSGLPRLVIRKSLNNLSLQIVKYDPKGDKVLVSAHTRDL-IKL GY----KGNRGNLPAAYLLGLLLAKKAKTA-KVKKAIFDIGLYAKVKGNLLFAALKGVVE NGLDVAH--NEEIFPS------EDRLTGEHIANYAKHLES-DKVKYDKQFSVYLK--QGL KPQDLKKHVEEIKAKI------------IKE----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAI-KAYPSRALPIGTIMETCDNSGA KVVKLVSVRK--LNTTRRRLQEGAVGDLVAVSVVKGKQDMRKK---VALAVIVRQKKSYR RPDGSRLSFSDNSVVIVKDVK-GNPKGTIFKGAIAKEAAE-RWPGIAKVASIVV---MVK -------------------------AKNIG---LE-VVP-PKQE-----------C---- -E----DVHCPF------------------HGTNVVRGRVFVGEVTKTDTHRSASVAWPR QNYLPKYERYEKRTSKIRVHNPPCIN--AQAGEKVKIAECKAISKTKNFVIIEK------ ----------VK------------------------------------------------ --------------------------------------?????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????????????????????????????????????????????-------- ------------MQKARIKLASPDIGKINEISNSINEIIKKTKVKVNGPIPLPTRRLKLT TRKSPDGEGK-------ASFDNFEMRIHKRLIDL-AVDERALRLVMRVPIPEGVNIQIEL LE---------------------------------------------------------- -MKQ--EWSKT-----WKSSIQPRKQRKYVHN-AQLHTRQNL-MHAHLSKELRTKY---- ---------------------GRR-NFGLKIGDKVKILRG--QFR--KKEGKITKVMLKQ GKVYIEGIETLKTDGS-KTFYP----------LNPSNLMITDLNLD-------------- ---------DKK-RK---------SKLEVKEAPKEKPKKAPKEEKKVEEKKIVEKK---- ------------------------------------------------------------ --------K--------------------------------------------------- --------------------------------MVGLRSFSCYRNV--------------- -E-RAYTRKSKYR---NKAFIRAV-PTSKIVKFVFGDK----QKDFPY-RVDLSSKQPM- -QVRHNAIEAARLMIVRRL-NVSVG-K-NYRLQIRQYPHHVLRENKMLT-GAGADRMQTG MQKAFGRAVGLAARVKP-GTIIFSVYV---D-KDGVDHATKAIKDCFIKL--PCACAF-- ---------------------A-----VEEVPKK-------------------------- ------------------------------------------------------------ -------------------------------MLN-DTLATALSNIQNATDASKKVCIVRP ASKMIMQVLQIMKDNHYIGDFKLIEDGC-GNIIEINL----------------------I GSVNKCKAIKPRLSFTNIDYEKYEK--------------------RFLIAHGMGLILVTT SQGVMTLEQAQEKQIGGKLLAFVY-----------------------------------M LPKERL------------RKEIEIPEGVQVMVDGK-----TIKVT--GPAGEVQRILA-Y P-T----LEIKV-EGNK-VMFE---PK-VFS---KKEKMIINTFVAHVNNMIKGTQEP-F IYKLKIASSHFPMNVAIQ---GKE--VI-VKNFFGEKIPRKAKIV--EGVKVDISGD--- ----IITVTANDREAAGQTAANLEQSTRITN---RDRRV----------FQDGIWITEKA GRQM-------------------------------------------------------- ---------------------------MANPHHPRRGSLQFWPRKRAKRSYARVNAW-P- S-TN-----DPKLLGFIGYKVGMSHLATSSIFPNSTKE--QDGINYAVTVIECPPIKPYS LRFYKKT--YDG-IE---LISEFFTKKTDKE-----L-----KRKI-------------- ----KPS---K-----------KE-----------------------GSIPE-------- -------DFDFLRLVVYTQP-----KLAGVGKKKPELIEIEVGGKDNA---AKLEFAKGL FGT-EIKISDVFKEGQQLDIHGVTKGKGFQGTVKRYGVKIRQH--KSEKTKRG--IGNL- GAWT-PKRVS-YTVAQPGKMGYHLRTDFNKVCLKLGN---DPK--EVNQDGGFLHYGLVK SDYIILKGSVMGSAKRAITMVDATR---P-S--TRK-MQDP-KISYISTSSKQGN----- ---------------------------------------------------????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????????????????????????-- ---------------------MGKRIITQR-------------RGRGTLTYRAPSHRYK- GALKHR-K-LDDNEKNNVVYGK----VADLVHCPGHSAPLAKIKFENKEE-ILIAAPETM KVNDVVASGN-------------KAP---IQVGNTTMLRNIPEGTYIYNIEARSGDGGRF VRCSGAFARVLVN-NG--E-KITIKLPSKKQK---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------MA----------------------DMKQI KVEKVTLNMGVGGPGPNLDKAIKLLETI-TGK-KPVTTKTK--K--RIPTWGLRPGLPIA TKVTLRGK-DA-EVLLKRLFEAVEKRLHPKRFDDQGNFSFGIKEYLDIPGMTYIIEIGMM GLEVAVTLQRP-GFRVKKRRICCKKIPIRHKINKEEAMNFITEKYGVKV-QKTE------ --- >GCA_018396705 ------M-PHKL--RKIRK-KRGSR--TCGYGRVGQHR-KSGSKGYR-K-AGRHKHGWTY VMR-----YEPE--------------------------Y-F--G-------KK-GFTSPQ SIKR--IV--KA-----I-NVGELEE----NIEKFQP-K-----E---------EEGKIF VD--LEKFG--ITKLL----GTGKVTKPL-VVKV---TSCSRSAAEKIKEAGG--QVL-- V--ESM----------------------E----ESEE----------------------- ---------------------------------------------------------MAV V--------------------KHFISKSKKRAEI----------------DEFLQRKL-E RAGYGGVNIA------ETPLGTHIVIYAMRPGLVIGRSGETIRELAKTLEEKFGVSNPQI SVS-EIEVPELNPHIV----------ATRIASALER--GVHFRRAGFWALNQVMEAGALG VEIIISGK-L------------RT-------------ERARYEKFK-------------- ----AGYLPKCGDPAIKYMRKAEVHVQLKPGIFG-------------------------- ----------VKVRIM---------------PPDA----------KFPDKI--------- ------------------------E-I---------------AETL-P-AEVESEV---- ------------------------------------------------------------ ----------TEDS---------------------------------------------- ------------------------------------------------------------ ---KP------------------------------------------------------- ----------ADTAPREVEK-EKE------------------------------------ ----VEETSGEEEAAK-------------------------------------------- ------------------------------------------------------------ --------------------------------------------MAKTVKVFDLEGKPVE KIKLPPIFET-PIRPDVIKRGVLAIQSTMFQPQGRDPMAGKRTTAESRGVGL-------- ----GIARIPR-IKG-----PTGRGAFAPGTVGGRLAHPPT-----PEKKIVKKIPKKEK RLALFSAIAATASKEIIVSRGHAVE--GV-PQIPLVVVDELESLKKTKDVEETL---IKL GLLADLYRVKES-TKVRAGKGKLRGRRIKQAVGPLIV-V-S-EDKG-------------- -----IGEAARNIPGVEVVPVKELNAEILAPGTHPGRLTIWTKGA---IETLDK--IYCR SEVA-------------------------------------------------------- ---------------------------------------------MARNAR---YCVPYR RRREGKTNYRKRKALI-LSGKPRLVVRGSLKNILVQIVTAKPRGDEVLVSAHSRELLKKF GW----RAPRGNVPAAYLTGLLCGLKAKAK-GVDEAVLDIGLHSPTKGARVFAALKGVLD AGLSVPH--GEEKLPD------EDRIKGLHIAQYARSLSV-NAEKYMIVFSKYLE--NKI SPEQLPEHFEEVKKAV------------VAAFKGG------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---GRGRGE------MAAKAKTRGL-VAKG---VIGQ-RPKISRGLPTGAILKCTDNTGA RELRLIQVLG--YKGRLGRLPSAAVGDRVTVSVKRGTPDMRRK---IFQAVIVRQKKPFR RADGVWIQFEDNAAVIITPE--GEMKGSEIRGPVAKEAAE-RWPRIASAASIII------ --------------------------MVMA---LT-FKV-PKKT-----------C---- -N----DRNCPF------------------HGNLPVRGRILEGVVVSAKMNNTVIVRHDY LKYVSKFMRYERRYSRIPAHNPPCID--AKEGDYVTIAECRPISKTVSFVVVEK------ ----------RE---------------------------------------------EEK ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MPREFTYRGFTLE--------------------QLQGMSMDEFILLL PARQRRSLQRGL------STEQRILLEKVRKAREAM-CKGGSI--T-IKTH-ARDMV--- ------ILPEM----------------------------VGLTIHVHNG--------KEF V-----------PVEIKPDMIGHY----------------------------LGE----- ----------FAVTN-KPVKHGT------------------------------------- -------------PGIGA-SR-------------------------------SSMYVPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------VRKARIRLTSTDYKKLEEVCQELKSIAEKTGVKMVGPVPLPTKRLKVP VLKSPCGEGT-------STWDKWELRIHKRLIDI-DAEERAMRRIMRIRVPEEVHITIEL V----------------------------------------------------------- MQAA--------------KTSKPSKQRKALFQ-AADHVRYKQ-FAAPLSPELRKTY---- ---------------------GTR-SLPVRSGDTVRVMRG--DRK--GFEGKVSRVDRKK YRIYVEGLTREKVDGT-TVFVP----------VHPSKVMITKLNLD-------------- ---------DKW-RR-----------------------------------KILERRKK-- -----TKEKVEAATEKAVE-----VTEKPPEAVK--VEEKPSEEKAVAEFPLALE----A EKPGKKKKATKKAVKGAEAAKPEAKTGTRKRK------------SSEEL----------- -----------KVG----------------------MRARNYREV--------------- -RGQPYTR---------KEFVKGF-PQPKITKFTMGDP----NAKFEY-EARLIALERA- -QIRHNALEAARVATNRLL--MDKLSN-NYFLQVHPYPHVILRENKMIF-GAHADRLQDG MRRAFGKPIGTAARVEP-NQTIITVRV---N-ANGVEVAKEALKRGAAKL--PIPCRV-- ---------------------V-----VEKAEVKEAKAS--------------------- ------------------------------------------------------------ ---------------------------------M-DVLANGLTTILNNELRNKRECVISP ASKLLGKVLRVMQLHGYIGEFEFIDDGR-AGKFKVQL----------------------L GRINKCGAIKPRFAVSVDKIEDWEK--------------------KFLPSRDVGLLIIST SKGVLSHRDAKEKKIGGRLLAFVY------------------------------------ MRAVEV------------SKVLQIPDDVEVTLEGK-----KVTVK--GALGSLTRDFS-Y A-P----ISMEL-QGKT-LRIW---AN-WPR---KKESALVGTVYAHINNMITGVRKG-F TYKLKIVFSHFPISVKVQ---GNT--VL-IENFTGERNPRKAKIV--GNAKVKVSGD--- ----DVIVQGINIEDVSQTAANIEQATKVKR---KDPRV----------FLDGVYLYERG EGMN-------------------------------------------------------- ------------------MG-------HRKHHAPKHGSLAYLPRKRAKSILARIRYW-P- E-IQAD---TPKLLGFIGYKAGMTYAVVVEDRKRSPNF--GKEVVRPVTVVETPPLLICG VRAYTKT--PYG-LR---TFAEAWMEDPPDD-----L-----ERVL-------------- ----TIP---EKF------NTAEN-----------------------LKKIEEN------ ---LD--KISKIRVIAITQP-----RQTGLPKKKPDISEIEIGGGSIQ---QRFEYAKSI LGK-TVSPAEVFREGQHVDVIAVTTGKGFQGPVKRWGVKILQH--KGRKTKRG--VATL- GPWN-PHHVL-YTVPRAGQMGFHQRTEYNKRILKIGK---DGK--EITPKGGFIRYGIVR GPYILIEGSIPGPEKRPIKLRYPAR---P-P-KEIP-EGPP-QIMYISLESPQGK----- ------------------------------------------------------------ ----MPEWGYSIPE-------------------------------------EALDPEKTV K----------------------------------------------------------- -----------ASGREVR-VSPKSAREICKTI--KGMTLNEAKRFLLDVIAKRRAVPFTR FKK-KAGHRH-----GLE--KAYA-GRYPVKAAKQILKILGGAEANAENKGL-DTERLKI IHASAYPGMKIKHYMP-------RAFGR--ATPKFETL-THIELVL-------EEQPETV ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------TEES------- ------------------------------------------------------------ ---------------------MGKRIRVQR-------------RGRGGPTFRAATHKRV- APACYPPPL--KDMYGSVMKGI----VEEILHDPGRGAPLALIRFENGEE-CYIVAPEGM YVGQQMEMGG-------------EAH---IDIGNILPVGKIPEGTLVCNIELKPGDGGKI AKSSGAYATVVAH-TP--Q-GTMIKLPSGKTKYISDHCRATIGVVSGGGRTEKPFLKAGA KFHLMRARGRKYPRTRGRAMVAAVHPYG-SSK-RSA---R-K----VTTVSRNAPPGQKV GLIAARGTG-------RRKKRVKEGE---------------------------------- -----MSEDEIRKKW---------------EEN----------------------PMLKP KIDKVVVNISVGKSGEPLEKASKVLKEL-TGQ-NPCKRKAK--K--TIRDFGIRRGEPMA CIVTLRKQ-KA-LDFLKKVLHVIDYKLPRSCFDKHGNFAFGIKEHIEIPGVKYDPEIGIF GMDVCVSLNRP-GWRVKNRQRARSKVGAGHILTPEEAMVFVKDTLGVEI-V--------- --- >GCA_015122065 --------------MKSRK-LRGSS--TAGRGLGKRSRSGAGRRGGRGR-AGGGKR---- -------------------------------------------G-------QQ-NFASIK FYLK--ET--KAEKKMPL-NLSYLQS----HLDKLKR-KGII-QE---------KDGKLV VD--ITSGG-EYTKICGKFKGQGLKLSVY--------GKTSKQAKENILQNGG--EVN-- ----------------------------E------------------------------- -----------------------------------------------------------M QP-------------------KKMINALMKEQVT----------------RDYLFKLF-S KFGISDIKLE------KTPLGERVVIRTPKPRAIINRASNELRIASKKLGEIFEQSPPRI EVE-ESEDPMLDPNVV----------ADALAFRVARFGPLKYKVIAHKMLDSIMSAGAIG AEIEMGGV-IK--------------------------ERAAHFKFRP------------- ---NGGILPKSGQIEDYGVRKGQKQLLLKRGVIG-------------------------- ----------IKVTIV-----------------------------TKSSKLGGI------ ------------------------N-I--------------------------------- ------------------------------------------------------------ -------------------------SDGRENR---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------GP GDGASKDEHKEDTGSAAS------------------------------------------ ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????----MVKVNR--------- -----RTNYRARLGML-KSKLPRLVVRKTNSMIIGQIVEYEKSGDKTLSAVYSKEL-RAY GW----NFGLKNSPAAYLAGFLLGKKSSAK----EAILDKGSSTLKKDSFIYYFMKGASD AGIDVHT-KEFDI--------TEDRLFGKHIIEYASKGTTGN------QFSSVGK----- AINNMKDEFDTVLKKL----------NEYGK----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------M-KAAISKPINVGSYISVADNSGA KIAKVINVRG--YHGVKGRQPRCGVGDTVFIVVKKGNQDVIHK---TFPAVVIRQKKVFR RLNGLRLSFEDNACVLVKEIDKYEPLGTAIKGPIPREISI-RFPNVSKVAFKVV------ ----------------------------MQ---YDDLVK-PEVE-----------C---- -N----DKNCPY------------------HGTLKVHGSRFEGVVVSAKSKRTAVVQWIN FERLKKYDVYREKKTRVLAHNPDCIS--AKVNDRVVIYETRPLSRWKKFVIVRK------ ----------I------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------MEEFKFKSKSVE--------------------DLSKIPVDQLASVV NSSLRRRMKRGF------TDQQKKLIEKVEKAKKNG---------KPIRTH-LREMF--- ------ILPSF----------------------------VGITINVHNG--------KEF V-----------PVAIKPDMVFHR----------------------------LGE----- ----------FAITV-KQVRHGT------------------------------------- -------------PGLSA-TR-------------------------------SSSFVPIK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLTSTDTKQLKVVCDQIADISRKLGTSIKGPIPIPTKRIKVT TRRAPNGSGR-------ESYETWELRLHKRVIDM-QADPKALHLIMKTPIPKEVNIEMEI MGP--------------------------------------------------------- -MKD---FSKH-----WNGSKSPRKQRKYRAN-APLNLKHRM-VSAHLSKELRQQY---- ---------------------HTR-SFPIRKGDTVLVMRG--KFK--GSEGKVEKVYTKQ LRVTVDSAKITSKKGT-KIPIK----------IRPSALLIKELNLS-------------- ---------DKL-RE-----------------------------------KSLVKYGK-- -----AR----------------------------------------------------- ------------------------------------------------------------ --------------------------------MAKLRPGRAYRSM--------------- -K-QPYTRKSKFK---EKNYTKFA-LHTKITQFHSGNM----HNTFKK-RVEVISKSTL- -QVRDNALEAARIVANKYL-TDSIGEE-NFHIQLVSIPHHILREHKLAT-GAGADRFSAG MQKSFGKPIGLASQISA-GDKVFEIFV---N-EDHVNEAKEAADKIKKKLGFKTLALV-- ---------------------------I-------------------------------- ------------------------------------------------------------ --------------------------------MT-DQVSNALNVIFTSKISAKKECIITP MSNFILKILDIMNKGGYIDKYEVINDAR-GGFIKVTM----------------------N ENLNKCKSIRPRLPVKINEIQKYEE--------------------RFLPAIGFGMLIIST SKGLMTNAEARQNGIGGNLIAYVY------------------------------------ -MSTKF------------STQL---DGADVKIENG-----EISVS--GPKGELKVKVV-Y S-----FLSVRK-EENT-LYIE---CK-KDT---DYQKAIAGTLAAQVRNMVKGVKEG-Y TAELELVYIHFPASMKLV---GDK--LV-VENFVGERKAREIFIP--KDVKTKVQGT--- ----KIILEGIDKYKVGQVAGTIEKNVQIKN---KDRRV----------FKDGIFIVKKP E-----------???????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????--------- ----------------------------------------------------------MI K----QVS---------------------------------------------------- -----------AKSERVQ-VSLKHVHEIMESV--TGKNLDKAIKHLDGVLEEKRFIPFNK YG--GKGHKS-----GVP-------RGYPKRATKFVISLLKELKSNAKNINL-DEASIII KKYSLGRGKYPRFPSG-----AVYRHGKF----------TNLVVFG------EAEAKAPK ------------------------------------------------------------ ----------------------------------EEKKTSA------------------- P----------------------------ASAVEATNEKNE--------ENNNDATKEND ------------------KRTDEGAG---------------------DKGLPVQALQ--- ----------------------MKVPRSRR-------------RGK-SRIFRANTFKAI- ADTRI-------ISSNNAMNFK----VEDIIHDSYRTAPLMEIRFEDGTV-SYLPAFNGA YVGQILTFLK-------------GGD----KTGSIDSLKNIPTGANVYNVELRPNDGGKL VRSGGLSAKVIKK-EK--G-IVSIQLPSSRIIDINENCRAVVGVISNSGRMNKPLYKAGN NYHLKRARGRYWPLSAAVAMNAYEHKFG-GKRRSSQH----K----SKSVSRNAPPGAKV GTIAPRRTG------VK------------------------------------------- -------------------------------MNK-------------------DNKMRDI RIEKVTLNVGVGKAGAELDKIENLLKSI-AGA-QPFKTTSK--R--RIPEWGVRPGLEIG TAVTLRGK-AA-EEILGRLLEGIDKKLSKSKFDEGGNFSFGIPEYVHIPGVKYDYTVGIV GLSVAVTLFRP-GFSISRKRVR-RTVGNSHRIKKEEAINFISNKYNLQV-SD-------- --- >GCA_002688775 ---------MKRTGPTNPI-LFGII-------------------------AELKKRSNSQ N---------VNIWKR------------------------V----------AK-DLERST RQRR------------VV-NLSSINRY----------------TK---------EDEVIV VP----------GKVL----GAGDLKHKL-TISA---FQFSSGAKEKIEKNGS--KIV-P LLELSKD------------------------KPNGKKIKIIG------------------ ----------------------------------------------------------MN K--------------------IKFDSELIKLITLF---------------ESMTGAKV-K DC-IANDRLI-------------FIVQENEMGKAIGKNGANIRRIENSLKKKIKLVEFSN DVL-QFVKNMIYPT--E---------------------ALDIK--NEDGVI-TIQGKDTS TRAILIGR-----------------------------ERQNLNHLS-------------- ------------------------------------------------------------ ---------SIVKRFF-------------------------------------------- ------------------------D-I--------------------------------- ------------------------------------------------------------ ----------KEIKVV-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????????????????????????????????????????????-------- ------------MQKARIKLASIDINKINDVCSYIKDIADKTGVDMRGPIPLPTKRLKVT TRKSPDGEGT-------ATWERYEMXVHKRLIDL-GLDERALRLVMRVPIPEGLNIEIEM LE-----MTRE--------------------------------------------DETIF ALRT--TANREDQVMDFVTSNATKKKLEVYSVIRTHGMRGYIFIEAATKTDAEQAAFNIP YARGILPHPVKYKEIEHMLEQVKH-EMNIQKNDIVEIISG--PFK--RENAKVTRIDKAK EDVVVELLEA-------AVPIP--------ITVKMDAVKVIRRETE-------------- ---------TEI-KKD---------------------------------------DTE-- ------------------------------------------------------------ --------EDSL------------------------------------------------ --------------------------------MARIRKFVAYRRQ--------------- -K-RPYTRTSKFK---SKAFIRMA-PNVKVVRFNTGDP----RKEFNC-TLKLLSKSKL- -QIRDNALESARQTSNKLL-ESNLGLN-GFHMKVTVYPYQVIREHALAA-GAGADRFSSG MAHAFGKPAGVAARVKK-GQTIFQIKV---D-KQNIELAKKALERASKKI--PCSCLI-- ---------------------T-----VSEKK---------------------------- -------------------------------------------????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????------------------------------------------------ ----------------------------MVLKIARRGASGYVPENTMAXFEKSL------ E-------IDCDVVEFDIHKTKDNQIIIMHDENVGKTTD-GLGNIRDLTLKE-------- -------------LK---MFHEPNGESVPTLQGVFDL--IKNKKKM-------------- ----MLD--IKDQ------NMERE------------------V----LQSVNDN------ -------DLEENVIIDSDIPE----VVKKIKKMNPKI-HVFLGGVTKDNYRETIQDAKKI GAE-MIKVQNILVNGDLV---------------------------NEAHSHRI------- GVYV-------W-----GQKKY-----------------------QIS------------ --------------KRC------------------------------------------- ---------------------------------------------------????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??? >Bin129_genes -----MK-IHKK--KKSVR-LRGTNSGGHGS--RKKWK-GSGHRGGKGM-AGTGKRADQK KSLVIKK----------------------YGNK-----Y-F--G-------KQ-GITSKG TAVS--KL--KV-----I-NLGQIQKNHVNLMKKFGK-N---------------GV---- II--LE-----KYKVL----GNGDLKEKL-KIKA---KEFSESAKAGIEKAGG--EVVEE KKEIKKV-------------EAKEKVEVKKVSKSVKKESVAVEK-------KAE------ ----------------------------------------------------------ME E--------------------RKFIRLKKEEFGI----------------KEYIKRNL-G KGKISNLDIE------YTPVGEKIIVSTSRPGLVIGRKGEKIQELTRVLRDKFKLENPHI EID-EIKNPLFDSQLV----------ADEIALALERMGNLKFKVIAYRKLQEIMKAGALG CEMRLTGK-L------------PS-------------ERAKSWRFA-------------- ----EGYLKKAGEPS-KEIDRAQATALTKTGIIG-------------------------- ----------VKVAIM---------------SPDA----------KIYDRI--------- ------------------------D-I------------D-AEIKRQ--INNIE------ ------------------------------------------------------------ ----------EEVV-----------EEEEEKPK--------------------------- ---------------------------K--KT---------------AKKKISKEIKKVI NKKE-------------------------------------------------------- ------------QTEASEKKSAKILKKGAGVEVIEESPDLKPEEDGTAMMINEELEEGVP QDQIDKDIKKKVDEGK------D------------------------------------- --------------------------------IKDK------ETKEN------------- KE--------------------------------------------MKIQVLNKEGKKVS EKE-TQVFSE-PIREDVIRVIVEA--ERIKHPNSPKYRAGMDISASGTPSKR-R-HVWKT NTGKGMARLPRKIFSRRGTQFNWEAAVVPSTRGGRRAHPPH----GNVNL--NKINKKEL KKALMSSLSYVSSVAELKKKYSTLSDVDVKTKLPLVVSGEVLNL-NNRDFFVML---EKV -LGELNNVAVQK-KTIRAGIGKMRGRKNKRNAGLLLV-I-G-NEEKF------------- -----------KIKGVEVLKVKELTVSDLASN--GARLCMFSEMA---VDNLEEIKKGK- ------------------------------VGEGKKK----------------------- --------------------------------------------------M---KRLDKR RRQECKTDYRKRLVLL-KSNLPRLVVRKSNRYLILQIVESKHAQDKVLYYVNSKEL-LAK GWPEDKSGSLKNLSAAYLSGMLLGKKVLDGGLKGKVILDSGLIPNTKGSKVYAVVKGFSD AGVEIPF--DEKVMFS------EEEIAKKIGKD--------------------------- -------VFEKVKGGLK------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKGV-AANLTRGLNLGSNVLASDNSGA RIVRIVSVKH--GKTRKGRQQYAKLGDWVKVSVRKGDPTMKGE---VFDAIVIRQKKPFR RNSGERIAFTDNAVALLKDEK-GNPKGTQVKGPVAREVNE-RWPFVGKIAKFVV-----M -----------------------KAKQKLQT---------GT------------------ ------------------------------------RGRIFKGAVIK-KFPKRVVIEFER TIYIKKYERYAKRKTKLHARLPEEMTKEVNIGDYIEIRECRPLSKIIHFIVIGK------ ----------VS-------------------------------------------K-EEG K----------------------------------------------------------- ------------------MAEENKP----------------------------------- ---------TESK----------------------------------------------- ---------KLLMKKKEFSYRGQALE--------------------ELKKLDIREFAKLL KSNEKRTVLRQH-------DELQRFVIRCKNKIKND---------KQIKTH-YRHLV--- ------IVPHM----------------------------VGFKISIYNG--------KTF F-----------PVEIIGEMLGHR----------------------------LGE----- ----------FSVTR-NKIKHGA------------------------------------- -------------AGVGA-TR-------------------------------SSASRSVK ------------------------------------------------------------ ----------------------------------------------------???????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- -MKA--KFSTS-----WIGSKLPRKQRKFRAN-APIHIRHKM-ISVHLSESLRKKY---- ---------------------GKR-NFPVRKDDDVKIMKG--EFK--GKTGKIETVDLKK LRVTIGGIYRTKKDGT-KVSVY----------FNPSNLLIKELNLE-------------- ---------DKK-RVAALNRGATA---EVKKVVKAKPLP-----------KSEEKETE-- -----KAEG--------------------------------------------------- ---------EKK------------------------------------------------ --------------------------------MVAVRKALAYSKR--------------- -KPIKNTRRSKKQ---QLSYIKTV-PPQKIVKFNMGDYQGFEEGKYKI-KVTLSTQENI- -QIRDLALEAIRQSIHKDM-TKLLTQK-HYFLRCNVYPHNILRNNRIFSGGSKGERVQTG MKKSFGSPEGRAATIKR-GRPIFTLYF---NGEEHLPRVRKFFKKVTPKL--ACKAKV-- ---------------------------VVELSK--------------------------- ------------------------------------------------------------ --------------------------------MSQDIVADTLNQIMNAKKARKTEVIVKR NSKLLRKILDIAKESGYL-DYEVDGR-----NVKIQI----------------------K Q-LNEFKAIKPRYTVSVKRINHYVR--------------------RFLPARNFGLVIVST NQGLMNHEEAEEKKLGGCLIAYAY------------------------------------ ------------------------SEGINVEMVEG-----ELIMK--KDNNEIKRKIH-- P-V----IDLKV-EGNK-IMVS---CA-RVR---KTEKKIFGSMKAHIRNMIKGLEEP-F KYKLQISNVHFPMTVTHNK-EKNE--LV-VKNFVGEKTDRIVKLV--EGVDVKTDKE--- ----FIELECHDREKAGQCAANIEKATKVRN---KDRRI----------FQDGIFIIEKP GRKFL------------------------------------------------------- ---------------------------MPKHGHMRHGSLQFYPRVRAKKILPRV-SW-K- V-LKRE---DVNLLGFIGYKVGMKSAYVKDSTPNSLTK--NQRITIPVTIIECPTMKIFS VRFYKN-------NK---VIGEVLNNNIDKE-----M-----KKKV-------------- ----KVP---K--------EVKKK-----------------------IEDYKEG------ -------DYDNIRLIIYSQV-----KKTGI-KKKPDMTEIGVSGSL-S---EKLEFVKNN MAK-EISIKDV-FNDGVVDVRGITIGKGNQGPTKRFGLSLRSH--KSEKGVRG--PGSG- GPWH-PARVE-YTQPMSGQMGFFTRTSYNHKIVLIGD--TEEN--DINIKSGFKKFGRIK GDYILVYGSIQGPSKRQVLITSALR---P-T-KIPI-KRKY-EFMELR------------ ---------------------------------------------------MAEQEQII- --ENKKQEEATKKEKEM--VDESKAKLEKPEI---------------KADVKDGE-EKKV E----E--------------KPVEK----------------KKVVEAPKV---------- -KKTEAV----VNGMSLH-VSTKHSIAICNFI--RGKNIEKAIAELEDAGKMKFAIPMRG ----EIPHK----------KGIMS-GRYPVKAIAEFIKLLKSLKSNAIANEL-ELEKVRI F-CVANIAARPYRR---F--------GS-----KRFKR-THVEI---------KLVPIVK ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------KIKK------- ------------------EKKK-------------------------------------- ------------------------------------------------------PKAYR- YKVTYP-K--------LGAEGK--AKIVKLFNSSAHSCPLVKVVVDKEE--FIVPAASGI YEGQEIWVGN-------------REENKVPEVGDIIKINDVPQGTKIFNVELVPGEGGKI LRSSGISGIVMNK-DE--K-KVEIVI-KRRRVKVNKHCRVTIGLAAGEGRLIKPLVKAGK KHHIMKAVGRKWHRTSAVKVNAIDHPFG-GGRGKRI-----K----SKIAKRNSPPGRKV GHIRPRKTG-------RKK----------------------------------------- ----------------------------MTNEN----------------------KMRDI EIEKMVLH--CGGTDEKHDKSMKLLEMI-TKR-KIQVVQST--R--RIPTFGISPGKKSG CKVTLRNK-EKIIDLLQRFFASFDNEISTKKITEN-QLCFGIPEYIEVPGLEYDRDIGIL GLEVMIVFKRK-GKSVKMRKAKRGSLPKKQQVTKEEIAEYLTKELGVEI-I--------- --- >Bin104_genes -----MT-ERKR--RKKNR-VRGER--THSKGDTKNNR-GAGCRGGRGR-AGATKGKFAS IGRL------------------------------------D--PR------KY-RLKPN- --TH-----GQA-----I-TLGDFDT----KLDKLVE-KDKV-VM---------EGKKYV VT--SNS-G--YEKIL----SQGETTKAI-ILK----INASKKAIVKIEAAGG--TFD-- FPK-------------------------KGMKKETKEESIEVTK--------SEEKIKE- ----------------------------------------------------------MI E--------------------RTFIKKNFNKMEL----------------EDYLDTKL-E RAGFCGIDII------KTPLVTRIVLHVAKPGLAIGKSGSTINELTRKIAEDYDIDNPQI EIQ-EIKSPNLNARIL----------AKKMASMIER--GYSWRSVSYRMIKDIMDSGAQG VELVVKGK-LS----------GKG-------------GRKRKQRVA-------------- ----IGYLKKRGHQS-KYVDKFKAAAYPKAGAIG-------------------------- ----------ITLSIV---------------HPDV----------VFPDKI--------- -------------DVN--------EVIAKTR----------------------ALA---- ----------------------------KEI----------------------------- --------VEQTKT-----------DEKAEEQ---------------------------- ------------------------------KEAVA------------DEKE------VPT IEKKD------------------------------------------------------- -----------VTADKK--------IED-------------------------------- ----KKEAPK-------------------------------------------------- -----------------------------------A------EKK--------------- --------------------------------------------MIMKAKIFGIDGTDKG SVDLPKVFET-TQHPIVIKRAVLALQTARLQPKGTDPRAGLKSSAQYKGMRG-K-STPLR TINVGKARLPR-LKN-RRHLLSGNVARVPQSVGGRRAHPPK-----AQKIIVEKLNKKEK RLALASAIAATAIKELVEKR-FIVE--G---ELPIIIEDKFEEVAKTKGVILAL---TKV GAGKDLDNAKSK-TRKRAGKGKTRGRTKKQKKSVLIV-T-G-ENSK-------------- -----VLKACRNLPGVESVTIGSLNVELLAPGAEAGRLVIWTKGA---IEKLTNGTKTQK VVKKEKKI-------------------------VKKVEKKVVKTTKKK------------ VIKKE------------------------------------??????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????------------------MKAM-SIPNNNALTLKSHVTCTDNSGA KEVYIISVFK--YKGIKRSLPKAGVGSIVNVVIKKGKPEMRGK---IERAVVVRTKQEYR RANGTRVSFEDNAVVLVDHD--GLPKASEIKGCVAKEVGE-RFPKIAGMASVVVMMIMSE ----------------------------------------TEKK----------AIEKVV KK----EETVAVKKAPKKELVKAVSKIITVEKTYPVRGNIFEGKVISAKANKTVTVQRIL TQYVSKYERYKKVKSKLKAHNPESIN--AKEGDTVRIGETRRISKTKNFIVMEI------ ----------L-------------------------------------------NEAKK- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MTKKEYTFRGKNLE--------------------ELQAMSVEDFANLC GSRARRSLKSGY---------DKKILQSVEKKKGDV-KA------KPIRTH-NRDLI--- ------VIPAM----------------------------VGTQFAVYRG--------NSF E-----------RLDIVEKMLGHY----------------------------IGE----- ----------FVFTR-KRLSHGK------------------------------------- -------------AGIGA-TK-------------------------------SSTAITAR ------------------------------------------------------------ ----------------------------------------------------???????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- ----------------MTKSSKPRVSRRTFLQ-MDMHTRSKT-ITGHLNKKLRKEM---- ---------------------EQR-AISLRKGDVVEIVRG--SFK--GKEGKITKIERGI GKIFIEKVIRKKSDGT-EYEVA----------IDPSNIIVVGIEKG-------------- ---------DKK-RF-----------------------------------KKSKKRDL-- ------------------------------------------------------------ --------E--------------------------------------------------- --------------------------------MG-LRPGRCYNNKKDKTRYGAKSHMSVH KKKRAYTRVAIRVP--RKNYIGAA-PALRIRQFNMGNP----EGKYNL-VADLRVKEYF- -DLRDNAIESSRMAINRKL-VKELGKD-GFFMKVRVYPSNLNRENKQAQ-GAGADRVSQG MSRSFGVPNSRSARMRK-DQIVFSVLC---N-KGEEAIVRDALMRAKSRF--AVDVYVK- FHDDTKSVGTIPAKKIRE-VVIE----LTEEQKKAEEE--KKAAEETKDGEKTE------ --GEAKDDEKTDEKA---GDDKKEDSKEDKKEEKSDDKKSKK------------------ -----------------------------M-PRN-PANSSRGHDVFSGKRRTDRGTKARP GEQLINRVVTRTIQSARAVEFSAAQKKK----VFVRL----DKHQKVVAEQLLRIVKR-S KKIDDWNLIDSTLAMLSTKGAKYSEKIGGQVVEISLTREHVWRVLRMLKSEG---LIKET NRLVKKQRD---------------???????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????------------------------------------------------ ---------------------------MASYNWPRRGSMAYYPRKRARKETP---SI-K- G--RGE---EAKALNFLIYKVGMTQILGKNAHKGSPSL--GQDVVIPATIVECPALKVFG IRAYSKA--EIG-ME---VLGEAISENIDKE-----L-----LRRI-------------- ---FNYQ---KA-------SEKKTTKK------DSKKEEKKA--KTTVEDLEKR------ ---IA--DIEYFTLLAHTQP-----KKIGF-KKKPDVTEITIGGKK-E---EQLSYAKEK IGK-ELELDEIFAEGDFLDVKGVTKGKGFQGVIKRFGVKIQRP--KA-KTRRI--VGSI- SPWN-PSTVM-FTVPRPGQMGYHNRTESNKKLIRIS---TDVL--GINPKSGYPNYGMVK NKYGIIVGSIPGPAKRCLAVRKGIR-PVAKSKIQLE------SIEKVLVK---------- ------------------------------------------------------------ ----MAKKNYQAT--------------------------------------VGK-ESKTA K----------------------------------------------------------- -----------AMTTNAN-ISLKYSTEICNQL--KGKNVDKVIAWLIRIVNHEEYLPLKR YHK-KVAHRK-----GDSKEGVKS-GRYPQKAIKAFLTLLNSVKSNADFKGL-DEDKLTI IHAFASMGVARTTYQS-------K--GKIGGKARRKSS-THIEIVV-------SEVKA-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTLIKDTGRNAIMTTIVFDNGQS-ENVVAAEGI YVGQPIEQGI-------------GAN---IAIGNISYLREVPEGCPIFNVEKTSGDGGTL AKTAGSYALLVTR-DQ--K-KATIKMPSGKLITLPLDVKATIGNASCGGKGDKPMVKAGT KFFAMKSKKKFWPSVRGVAMNAVDHPFG-GAQH-HA---G-K----SKSTSRNAPPGRKV GAIASKRTG-------RRKK---------------------------------------- --------------------------------------------------------MKEV LLEKVVVNMGVGSDPEQMKKSEQIIKLI-TGK-KPLKRSSK--K--RVPDWGLRPGVDIG LKVTLRKE-DA-IKFLKEAFVAKDNKILAKNFDKEGNFGFGIREHIDLPGIKYDPKLGII GLDVLVTLKKR-GYRVKHRKIEQTKVGEKQRVKKEEAIEFVKS-LGVEV-A--------- --- >GCA_003649035 -----MV-VRKR--KKITR-KRGSR--SYGWG--ARHR-GAGKHGGAGH-AGSGKRADQK K---------PSYW-----------------KT-----VVS--G-------KY-GFAPK- GVVK--PV--YA-----V-NFVDVEN----HLGSWLE-SGVA-KK---------DGDFFV VN--LKKLG--FTKLL----SKGKLSKKF-KFIV---DSCSKLALDKLKASGC--EII-- KE---------------------------------------------------------- ------------M----------EIIKEILKFLP-EEKISDVAFEAANIVLYTKDRKFFL DD----KGAI-----------RNVVNEFKKRIEL---RPDPSITIDEKKAEKIIKKLLPE EAGAGDILFD--------SKRSMVIIEAEKPGLVIGKQGSLLREIREQT-----FWVPHI RRT-----PALRSQIIENIRSVLYKHSAERRKFLDKVGHRIYDGWIREKKNEWIRITHLG GARQVGRSCIFLQTP-------ESRV--LLDCGVNVVG-EGSDAYPLLDAPEFDINQLDA VVLTHSHLDHSGFIP----------YLFKYGYRGPVYCTEPTRDVAALLTLDYVKILKSE NKEPPYDFDDVKEMVKHMVTLNFEEVTDI--TPDVRL-TLYNAGHILGSAM--------- ----------AHLHTG-NGLH---N-LLYTGDLKFGRSILLDPAAHVF-PRLETVIIES- -----------------------TYGGKTNI----------------------------- ------LPPEKEQDELFRNMI----SETIKRGGKVLMPVLGSGRAQDILVILDGMFKTGA LPDIPVYIDGMVWDITAIHTAYPEFLNKTIRKQIFHKDENPFLNPNFKRVGSQKERTKLV EDTGPCVI----------IATSGMLVGGPSV------FYLRQLADNPKN----SLI---- ----FSCFLPQGSLGHRILHGERE---------------L-------------------- ---VFKTGIKQEIVPVKMEIMRFE-L-----------TDHSDRKQLM------------- ---------------SFLFKCQP---------RPKKVIVQHGENSRILDLASSVHKIGRV ETVCPRNLESVRLK-????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????-----MSNKV---FTVPKR RKREGKTDYRFRMRII-RIGQLRLVIRRSLKNIWGQIVEFHPDGDRVLFSAHSREL-LKF GW----KLNKSNTCAAYLTGLLLAKKIKKE---LKCAVDIGFNVSVKGSCIYAFVQGVVD GGLLVNC--DKKVVPS------VERLRGEHIVAFAKLLKSDKS-EFERQFGGYLK--NGL DPEKVPVYFEEVKKKI----------SGL------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------KGKIPAAGVGDLVVASVISGRPDMRKQ---VVSAVIVRQKRPYR RLDGTRIKFEDNAAVVIKDEL-GNPKGTMIKGPVAKEAAE-RWPLIAKIAKIIV?????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????????????????????????????????????????????-------- ------------MQKARIKLASIDIEKLNQTCHHIKDIAEKTGVDMRGPIPLPTKRLKIT TRKSPCGDGT-------ATWERYEMRVHKRLIDL-GTDERALRLVMRVPIPEGLNIEIEM IDV--------------------------------------------------------- -MKN---WSKS-----WNKSIKPRKQRLFVRN-APLHVKSKL-MGSHLSKELRVKY---- ---------------------KSR-ALRVRKGDKVKILRG--QFK--GKTGSVERIDTKK QSVFVTGIEILKKDGS-KTLYP----------LHYSNLLIIELNVS-------------- ---------DKF-RLG-------------------------------------------- ------------------------------------------------------------ --------EKK------------------------------------------------- --------------------------------MARLRSFICYRGL--------------- -K-RPYTRFSKYK---RKSFVKSR-PHNRISRYTGGE-----YQDYDH-KVHLISKEAM- -QIRDQALESARQTMVRNI-EKNMGKA-GFFYQMRVYPHHILRENPLAA-GAGADRLSTG MAHSFGKPIGRAAQVYN-GQELLTVMT---N-KDKIALVKTALLKASHKL--PCKCKV-- ---------------------V-----IQ------------------------------- ------------------------------------------------------------ -------------------------------MMN-DPLANVLSSIVSYESRGKRVLLVNP VNGVIKDVLGIMKREGFVGDFESVSESK-GGFGNLHL----------------------L GRINQCGVIKPRFSVKVDEFVKFEK--------------------RFLPARDVGILIVST SKGVMTHYEAKEKNIGGKLIAFCY------------------------------------ -MKVPV------------SEFVELPEGVSASFIDD-----VLLVK--GAEGEVKRKFL-F P-G----VNVSV-EENK-VVVS---CS-LAT---KKEKKIVFSWLAHIRNMIFGSQKK-F QYQLKVCSGHFPMNVSVS---NGS--LV-VKNFLGEKSPRVLNLK--PGVSVKVNGD--- ----VIIVESCDKELAGCVASDIELLTVKRG---RDLRI----------FQDGIYIVKKP GRLVEK------???????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????????????----------- -------------------------------MN----------------------VMTIP RIEKVTLNIGAGKDQAKLEKGISLIKTI-TGV-EPTKTITK--K--RIPSWGLRPGLPVG CMLTLRKK-NA-VNVLKRLLAAKNNRLAESNFDKNGNVSFGIHEYIDIPGVAYDPKIGVL GLQVCISLEKP-GFRIKRRRYKKKKIPKKHIVSKEEAIEFMKKNFGIKV--GESA----- --- >GCA_012961245 ------M-AHKD--RKINK-KRGSR--TCGFGNTQKHR-GAGSRGGRGM-AGSKKHKWSY VSK-----YLPD--------------------------Y-F--G-------RR-GFKRPR AVIR--NT--RT-----I-NIKDIEE----NIDRFIK-EGIV-KK---------KTNNYY IN--LKEMG--YDKLL----GSGKPGHKF-IINV---DYCSESAMKKIKEAGG--RVN-- ITKLKE----------------------S----ETE------------------------ -----??????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????--------------------------------MANVYSLDGKKKG SLKLPDVFNT-EYRPDVIQRAVVSIQTNRRQPYAPFVLAGQQTSAAYFGRRR---GGFRQ TINRGMSRLPR-EKP-GGG-GLGRVRIVPQAVGGRRAHPPK------GKEWSKKINNKEY SLAFRSAIGATINKELVSKRGHIID--KI-RELPLIVDDKFEKLKKTKEIIDVL---NAL GLEDDIERA-RN-RVIRSGKGKMRGRKYKNKKSVLIV-V-N-DDKG-------------- -----VISGTRNIPGVDVVKLDDLNVELLAPGTHAGRLTMWTESA---IKNIDKTIK--- ------------------------------------------------------------ ---------------------------------------------MAKKAT---YVVQFR RKREKKTNYKKRLNLL-KSEKTRLVVRRSNRYINVQLVEYNEDGDLVIASANSRDL-KKF GW----KFHTRNTPAAYLTGLICGHRGISK-GIRGAILDIGLNPSVKSSRIYAALKGAID SGLKIPH--NEEMLPS------DDRISGIHISEY-------------------------- RNIEIDKEFKKVKNKI------------IKSFEGK------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---KYKNGAKKD--------MAKPLGVTKNLPLGKAI-TARVTRALPVGARLNCADNTGA KELEIIAVRS--YKGVRRRLPRAGIGDLVVASVKKGRVDIRGQ---VVLAVIVRQKKEYT RHNGIKISFEDNAAVIVDDN--GMPKGTEIKTAIAREVTD-KWNKIGSIATIVV---MAV KS---------------------EKTKTKSK-----VNKKAEKS--------KAECG--- ------DINCPI------------------HGTLPTRGIVLDGTVVSDKMDKTVIVERNY RIKEKKFERYRSARSRIPAHNPPC------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MARREFKFRGYALD--------------------KLKKMSMDELVEIM PSRVKRKLRRGF------TDQEKKLMVKIKNAQSDL-SEGKRV--KPIRTH-CRDMP--- ------ILPAM----------------------------IGLEFEIYNG--------KEF K-----------RVEIKPEMIGHL----------------------------LGE----- ----------FSMTR-QVVKHSA------------------------------------- -------------PGVGA-TR-------------------------------SSLFVPIR ------------------------------------------------------------ ----------------------------------------------------???????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- ---------MK-----KPSSKKPRKQRKWRLN-APMHRRRKM-ICSPLTKELREKY---- ---------------------NRR-NIPVRKGDRVKILRG--EFR--GTTGEVTRVSLRD YKIYIDGITAKKADGT-GIERS----------VDPSNVMITEIFME-------------- ---------DKG-RR-----------------------------------AMLERNVK-- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGLRPGRCYKWD--------------- -S-PAYTRVAKNP---QDSFITGI-PGSKVTKYNMGNL----TEKFDT-EVSLVTENRM- -QIRHNALEASRIATNNIL-EEKIGRN-TYRFKIRIYPHHVMRENVMAT-GAGADRVQSG MRGAFGKPVGRAARLNK-NQIVMSVYVN--HGEKRIKNAKTALRAAMSKL--PKKMRI-- ---------------------L-----IKPVNER-------------------------- ------------------------------------------------------------ -------------------------------MMH-DLINDAIVNIKNHERIGKSECIIRP KSKLLIEILKIFQKNGYIGEFEVSDDKG-GGNIRVKL----------------------I KQINDCGVIKPRFSVKHDEFTKWEQ--------------------RFLPARDFGILVVST NQGVMSHKEAKEKGIGGRLLAYIY???????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????------------------------------------------------ ---------------------------MAKTHRPRSGSLAYHPRKRAKRETPRIHNW-Q- E--SE----EVKLLGFAGYKAGMTHVIAFDNNTNNPTS--GLEVFIPVTVIETPPMVVAC IRAYRDG--YFG-KE---VYTEIWAKDLADD-----L-----LKKV-------------- ----SLP---KNR------SPEKK-----------------------LKELEKN------ ---LD--NVSDIRHIMHTQP-----RLTSMPKKKPDIMEIAI-GGTIQ---EKFEFAKNN LGK-EINVEDVFSENKFVDVVAVT------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------MELH-----------------------------------YSYMPEDESKIA R----------------------------------------------------------- -----------AIGRDMD-ISFKHAILICDKL--RGMMLRDAINLLDAVIKLDKSIPFRK FNK-GVGHRK-----GLGR---DAIGKYPAKAAQHI---------------------LRI ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRIITQR-------------RGRGGPRYRVPSHKFK- SNVKYP----SLEEYKEGIGGQ----VIDIIHDPARTAPVARILLENFKN-IDIIAPEGL QIGEWVEIGE-------------DAQ---PRIGSILPLCKIPEGILVYNIETVPGGGGKL VRSAGSFASIVSH-EKNTG-LTYVRLPSKRIVALNSNARATVGKIAGGGRKDKPMAHAGQ AYYAHKAKNKLYPRVCGRAMNAVDHPHG-GGRHPHV---G-K----PTTLSRNAPPGRKV GHIAARRTG-------LKKR---------------------------------------- ----------------------------MEYKN----------------------VMQKP RIDKVVVNIGCGQSGEKLVKAEQLLEKL-TSR-RPVRTISK--Y--RIPSWGIRKREPIG CKVTLRRK-EA-EEFLKRAFIAKDNQIKKSNFDEYGNLSFGIHEYIDFPGIKYDPDIGIF GMNISVSIERP-GYRIKKRRIKKSKVPTRILINREESVEFIKKRFKIDI-N--------- --- >GCA_015063285 ------M-PSRT--KK----FRGYR--THGRGK-KSGR-GAGIIGGHGM-AGYGKTGKIG MLK-----EDRN--------------------------Y-F--G-------RH-GFKRPQ CTVE--AN--RT-----I-NVGELSE----KIETFVS-MGFA-SK---------EGDAYK LD--LTEAG--IDKLL----GNGNIDFAV-NVTV---DSVSEKAREKIEAAGG--SIA-- E----------------------------------------------------------- ---------------------------------------------------------MAA E--------------------RKIVAEHVRRVLL----------------KEYLMKEV-S RAGFGGLDVQ------RTPMGTRVILTTERPGLVIGRRGQTIKNLTQVIEEQFGFDNPQI EVQ-EVENASLNAQIM----------AEKLAFSLER--GWHFRRAGHSTVRRIMDAGARG CYIIVAGK-L------------SG-------------QRHRTEKFK-------------- ----EGNIKFCGDTKAQFIEHGYAVAKLKMGVIG-------------------------- ----------VTVEIM---------------VKDA----------KMPADI--------- ------------------------T-V-------------LNK----------------- ------------------------------------------------------------ ----------TEAA-----------AVLPDL----------------------------- --------------------------FAAPK-V--------------------------- ------------------------------------------------------------ ------------EAPVEAE--TTEEVQ--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MATTNVYGVNGGVAG TVEVPEAFAT-PYRPDIIKKAVLAAAANGRQPYGPGARSGMRHAVSFRGK---------- --GTGSARNQR-IHG------LGKAGESPNNVSGRRAHPPL-----PERIWAQKVNKKEA KIARASALAATGCADCVKARGHQFD--DN-VSFPIVIEDSLNDVKETSAVIDLF---EKI GIGYDLDRAKEG-RKIRAGRGTMRNRKYRTPVSVLVV-V-A-DDERNA------------ ----PIFKSAANIPGVTVEEVKTLNTSILAPGGDAGRLTVYTKAA---IDAIGGWTQ--- ------------------------------------------------------------ ---------------------------------------------MATGPR---YKVAFR RRRELRTDYYTRKKLL-TARETRAVVRRSNKNITIQFADFAMEGDKIIASASTKELK-AM GW----EYSCSSIPAAYLVGYLAGKRAVKE-GIEYAVLDIGMQHVQHGGVLFATVAGMTD AGLEVPH--SDDVLPE------EDRLKG-------KHIDDGIE----------------- ------AAIDSIKQKM------------EAD----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKGI-AGNQTRGLQNGSQLDVIDNTGA KVIEIITVPG--YHGTARRVPSAGVGDLVIASVKKGTPAMRRQ---IVFAVIVRQRRPIR RPDGTMVFFEDNAAVITTDT--GEVKGTDIKGPVAREAAE-RWPRVSATASTII---MT- -----------------------AKIKDIG---ID-VVP-PTSE-----------C---- -N----DPNCPF------------------HGTLSVRGQTIDGVVATVRMNKTVVVERNY MRYMHKYERYEKKSSRYVAHAAPCLG--LKVGDRVTIAECRPLAKTVSFAVIEK------ ----------KE------------------------------------------------ ------------------------------------------------------------ ------------------MGKKIIAG-SAKA----------------------------- ---------SRRKS---------------------------------------------- ---RKKASAIQARRKKEFLFRGFTME--------------------ELLAMPFDEVLGLL PARARRTYLRGL------NYEQQLLFDNLKDATA------------PVRTH-RRDLP--- ------IIPQF----------------------------VGKTVSVYNG--------REF K-----------DVEIKPEMIGCF----------------------------IGE----- ----------FVQTR-KLPVHSG------------------------------------- -------------PGVGA-TR-------------------------------SSKFMPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------SQRARISLSGTDPAKVDSVCAQIKGISQRTGVDIRGPVPLPTKKLKVP CRKSPDGEGS-------ETWDRWEMRIHKRLIDL-DADERALRQLMRIQVPDGVNIEIVL RSA--------------------------------------------------------- -----------------MVSSKARTQRKAQAN-ATAHVKRKM-LSAHLSDDLREKY---- ---------------------GRR-AARVCKGDTVVVVRGNEDIR--NIEGKVVNVYTKT GRVAIEGVTIKQADGT-ETERP----------IHASNLVITKLNTE-------------- ---------DAW-RM-----------------------------------DSLSKKEA-- ------KE---------------------------------------------------- ------------------------------------------------------------ --------------------------------MV-RKPASMYRQI--------------- KG-QAYTR---------REYMGGV-PASRVSQYEMGNT----RQEFPV-TLTLKVKNRV- -QVRHTSIEAGRIAANKVL-TSQAGVA-NYHMTVRAYPHIVLRENKLAT-GAGADRVSSG MRQGFGKAVGTAARLER-NQAILTVRV---N-PDKVDVAKDALWRASMKF--PSPCYV-- ---------------------D-----VEQGKEFVN------------------------ ------------------------------------------------------------ -------------------------------MQS-DPLNDAMCVIKNASVNGKSDCTIEP SSKLIGRVLKVMQDAGYISQFEYVEDGK-AGKFHVML----------------------D GAINDCGVIKPRYSVKVTDVEKVEA--------------------RFLPAQDFGLLIMTT TAGVITQERAKELGIGGKLLAYVY------------------------------------ ---MTI-------AGKI-ESTIAIPGGVSVTYDAG-----TMKVK--GPKGELSRNFA-Y P-N----ISIAV-GEGE-VSVS---CE-YPR---VKDKAMVGTFVAHIKNMIVGVTEG-F KYDLKIVFSHFPMKVAVK---GDR--VE-INNYMGGHAPRYANIV--KGCTVKISGQ--- ----DVTVEGIDIEACGQTAANMEKATQRRG---FDKRV----------FEDGIYIVGKS HKVRQ------------------------------------------------------- ---------------------------MPQRRRPQKGSRAFGPRKRAQSQTPRLDSW-P- E-ISG----APKIQGFAGYKAGMTHAFVVDKRGKSTTS--GMEIQVPVTVVEIPPMKIAA VRFYESS--IVG-LK---TAGEVWAKDLDPL-----L-----DRRL-------------- ----NVP---KNH------E-EAT-----------------------FARYDGL------ -------DIEDVRVLAYTQPK----IVSGVPKKVPDLMELRIGGGTID---ERVAYAKQI LGT-EVNFTDFAPEGALVDVIAVTKGKGFQGVTKRWGVKLLSH--RNSK--HRRGIGNL- GPKR-PGYVR-STVPGSGQMGYHQRTEFNKKVVKVGT---DGA--EVTPKGGFLNYGEVR NNYILVHGSVPGPTKRLIRFRDATR---L-P-KKAE-TEAL-DVTYVSVESKQGA----- ------------------------------------------------------------ ----MVNSGYTAV----------------------------------------ADPDTTA K----------------------------------------------------------- -----------ALGREMP-VSPKFAREVAGMI--RGMKVETAQQALEEVIEKKRPVPLKR YNK-RVSHKA-----G-----VGP-GRYPVKAAKAILGVLDSAAANAEYKGL-DVSNMAI ATISVSRGRVIPGHMP-------RAHGR--ATEWNQDT-INVEVII-------QEVE--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRLIPMR-------------RGRGTSLYRSPSHRHV- DDVRLP-A---------FSEGT--AVIKDLIQAPGRTCPLAVLDVNGKTD--YQLAVEGT KVGQTIVIG--------------GTQ---VAAGNITALANIPEGTPVHNVEARPGDGGKF VKTAGSSGTVVSR----GD-KVMVLMPSGAIKEFSPNCRAAIGIVAGGGRGDKPLAKAGK NVLTLRSRSKAPFKTKGVAMNPVDHPHG-GGSHAHV--GG------PNCQKRTASPGQKV GFLPPKKKI-------RM------------------------------------------ -------------------------------MS----------------------TMRDL HVEKVVVNIGVGEAGERLAKAEKVLEMV-TKQ-KPVETLSK--T--VNRDLGIREGMPLG CKVTLRGD-AA-VDFVKQALSIREMRVPEYSFDKEGNMSFGISDYTDFEGMKYDPEIGIF GMDISVVLRRP-GNRITQRALLKRRIPKSHRVGRDEAIQYMKDNFQIEV-VQ-------- --- >GCA_003695045 -----MV-KFKR--KKVVK-MRGSK--THGGGSMKKRR-GAGNRGGRGN-AGSGKRGDSK K---------QTFQ----------------IKG-----IKP--G-------KR-GFKKK- GIQK--PV--IG-----I-NVGELER----ILPLWIE-SGKV-KG---------ND---- VN--LSQLG--FGKLL----GSGSITKAL-TITV---GAATERAIAKVEKAGG--KVV-- L---------------------------PDQEESNEESPAADAQ---------EE----- ----------------------------------------------------------MI E--------------------RQFVNQKKKEFQI----------------QEFIANEL-K RVGHSMTRIQ------RTPLGEKVIIHASRPGLVVGRKGANIKQLTKVLKKKFKLENPQI EIA-EVENVNLDPQIV----------AERISTSLERYGLNRFKGIGHRVMEDVMNAGAIG VEILISGK-V------------PS-------------SRAKRWRFY-------------- ----QGYLKKSGDIAINGVKTAYSIAKLKTGVVG-------------------------- ----------IQVRIM---------------PPDL----------KLPDDI--------- ------------------------K-L------------V-ETKSEE--ID--------- ---------------------------TQEP----------------------------- --------ITEEKQ-----------EESETSE---------------------------- ---------------------------DEAQE---------------------QPEEETD KE---------------------------------------------------------- -----------------EDAEKQE------------------------------------ -----ENGEKSD-----GE----------------------------------------- --------------------------------------------GSE------------- K---------------------------------------------MKIKVLTLENKEKG ERELPKQFRE-VVRPDLIRRAVLAIQSHKRQPYGADPEAGMKVSAELSRRRR-N---YRG SYGIGISRVPRKILSRQGRRMNWVGALAPGTVGGRRAHPPK-----SEKVWDQKINNKER RKAILSALAATVNVDYVRARGHKVP--D---SYPFAVDDSIIDVKKTADVSKVL---GAL GLGEELERTKE--RKVRAGIGKMRGRRYKKKTGPLIV-V-P-KECD-------------- -----LMKSARNIPGLEVARVDKLNAELLAPGAQPGRLVIFTEGA---LDRMEKENLFAQ ------------------------------------------------------------ ---------------------------------------------MKTGKR---YTVPFR RVREGKTNYKRRLNLL-KGGKTRIVVRKSLKHIIIQAVDYHPAGDKVLATVKSDEL-KKL GW----KHSTGNTPAAYLTGLLAAKKISGL-GREEFILDIGIHTPVKGSRIFAALKGLVE GGLNIPH--DESVLPD------DERTSGNHIASFRK------------------------ EAQSIANDVEELKKKIST----------I------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAV-PAKVTRALPVGSLVPTCDNSGA KMLKIFTVLG--KQTTKRRLPAAGVGDLVMASVKKGRPDMRKQ---VVFAVIVRQKKEYK RADGTRISFEDNAAVVLKDDK-GNPKGTIFKGPIAKEACE-KWPGVAKVASIIV---MM- -----------------------TNAKNIG---LD-VKA-PEKT-----------C---- -D----DENCPF------------------HGSLKVRGRQFVGTVVSDKTHKTVVVEWER RKPIQKYERYEKRRSRVQAHNPPCID--ASHGDKVLIAECRPLSKTKHFVVIQV------ ----------LGLDEAKL---IKEFESDDLPKTK-------------KKKEAEDAPSEDK KSK---------------------EGDEE------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MARKEFTYRGKTLE--------------------ELQGMSIAEFAELL PSRQRRTLKRGF------DEAQKALLKKLRAGKK------------EVKTH-SRDMI--- ------VLPEM----------------------------VGKTIKVYNG--------KEF V-----------AVMIQPEMIGHF----------------------------LGE----- ----------FSLTR-KRGQHGS------------------------------------- -------------PGVGA-TR-------------------------------SSASISVR ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKIASTDIDKVNQVCDYIKDIAEKTGVTIRGPIPLPTKKLKVT TRRSPDGEGK-------ATWERYEMRVHKRLIDL-SLDERALRLVMRVPVPEGLNIEIEM VD---------------------------------------------------------- -MKS--AFSPS-----WKSSKQPRKQRKYLYN-MPHHIASKT-MASHLAPALREKY---- ---------------------GIR-SIRVRVGDKVKVMRG--SFK--GEESKVERVDSQR RRVFLTKVERIKKDGT-KTLVP----------FDPSNLMITELNLD-------------- ---------DKK-RM-----------------------------------KNLSKPAK-- -----GSKG--------------------------------------------------- --------EDVKDG---------------------------------------------- --------------------------------MARLRKGVAYRRL--------------- -E-RPYTRKSKFK---AKNFVRAT-PSNKIVRYDMGDP----KKDYEL-TLNLVSKDDI- -QVRHNAIEAARQTSNRAL-EKNLGKN-AYHLKIRVYPFHVLRENPLAT-GAGADRMSTG MKMSFGKPIGLAAQVRK-GQVLMTLRC---N-RSALKTAKLALTRAARKL--PCSCRI-- ---------------------EE----VVEKKAASSSLP--------------------- ---EAQPEQSQEAEA--------------------------------------------- -----------------------------M-SLN-DPLANALSHILNSEKVAKKKIVIRP TNKIIENVLKLLQENNYVGSYEIIEDSK-GNSLVLNL----------------------L GRINKCGAVKPRFPVKVTEFEKFEK--------------------RYLPAKNFGILVVST PQGLMTHEDAKKKGIGGKLLAYCY------------------------------------ -MKQDM------------NEKITLPEGIQAAYENN-----ELVVK--GPKGEVRKKLL-A P-R----ISIAV-DGNS-VVLS---SK-NAT---KREKTLMGTFKAHIRNLIKGAQEG-Y TYKLKICAGHFPMNVSVS---GNE--FV-VKNFLGEKVPRKVKIR--EGAAVKVEGD--- ----IVVVESNNKEIAGQMAADIEQLTVVKN---RDRRI----------FQDGIFIIEKD SKKIA------------------------------------------------------- --------------------------------------MQFWPRKRAKKPYARVRSW-A- G-IA-----EAAPLGFAGYKVGMTHILINKAKTGGKSQ--VQRVFVPVSILECPPLKVYG VRAYRES--ENG-LK---VATEVVVKA-DKE-----L-----SRKT-------------- ----PGA---K--------KETKK-----------------------IDSLK-------- ---PE--DYSEFRLLVYTQP-----KLTGIGKKKPEIFEIAIGGKP-Q---EQFEYAKNV LGK-EISIGDVFKEGEYVDVHGITKGKGVQGPLKRFGIKRTSH--KSEKSVRT--PGSL- GGWVGQGVWM-WRVAKAGHMGYNVRTEYNKWLLKIGK---NPE--EINVKGGFLHYGIVK NDYIIVKGSVQGTPKRLLKLTKAIR---P-D-PKAP-REVP-PIHYVSTESPQGK----- ------------------------------------------------------------ -----MVYHYTAK----------------------------------------ADPETMA K----------------------------------------------------------- -----------AVGRDLP-ISTKQSIEICAQI--RGKSLQFAKRYLQEVVEFKRAVPFRR FNR-DVGHKK-----T-----GGP-GRYPVKACTYLLKLLNSVEANAQNKGL-SSEDLVI ETLVAHKGSGNWHY------------GR--HRRRKMKN-TTVEVIV-------RQKGG-- -------------KAEEKKNEK-------------------PVKSEARKEEKKE------ -----------KPKEEAKTRKEEGA---------SKQK---------------------- -------------------------------VSEDKTETKD--------QSSE-ESKNQS ------------------EKQDGND------------------------------KK--- ---------------------MGKNIVQQA-------------RGHGGPTYRAPSHRYK- GAAKH-----LAKKDE-TVTGR----IVDIIKCPGHTSPLAQVEYSTGET-ALLIAPEGV KVGAEVQTGP-------------EAV---PAPGNTLPLSKIPEGTLVYNIEAVPGDGGKF VRASGVFAKVVMN-LK--D-RIIVQLPSKKQKEFHPQCRASIGVIAGGGRTEKPFYKAGN KYKAMKARNKYYPVVSGNAMNAVDHPFG-NKRSQRK---S-K----ARPTSRNAPPGRKV GMVGARRTG-------RKKGKQA------------------------------------- --------------------------------------------------------MRQI RIEKLTFNIGAGKDQKQLEKGMKLIEKI-AGR-PPVKTKTN--K--RVPSWGLRPGLPIG CKLTLR-R-DV-EPLIKRLLEAKNNVLKPSCFDNEGNVSFGIHEYIDIPGVEYDPEIGII GLQVSITLERP-GFRIKKRKIAPRHIHRNHKISKEEAIEFMKEKFGIKV--GDDDLQ--- --- >GCA_003562145 -----MA-HNKR--KKNSR-QRGSW--THGWGAKKKHR-GAGHRGGRGA-AGSGKKGDAK K---------PRYWKE---------------KY-----F----G-------KT-GFT--- -SLK--KI--HSKE-KSI-SLSMIND----KLDKWSA-EGLA-VK---------EDDALK ID--LGKAG--YAKLL----GTGNVKAKL-DVTV---SQASAKAKQKIEAAKG--KI--- -----------------------------TVLSETKKD---------------------- ----------------------------------------------------------MI E--------------------RKFVAQNIRELEI----------------KEYLYKEL-G KVGLSNVKLQ------KTPLGEKILVSASRPGLVVGKGGANIARLTSELKEKFKLDNPQI EIE-EVTDPRGNAAIT----------AEVIANSLERYGPVRFKGIGHKALSTIMDSGAHG VEILISGK-I------------PS-------------ARAKTWRFY-------------- ----QGYLKKCGDISIAGVDKSKQVAKLKSGVVG-------------------------- ----------IQVNVM---------------PVTT----------SLPDKV--------- ------------------------T-F------------K-------------------- ----------------------------SE------------------------------ ----------EQVK-----------QEE---E---------------------------- ---------------------------EAAKR---------------------EQEKKTA ------------------------------------------------------------ ------------EEKRPAKKKTA------------------------------------- -----RKAAKK------KTAKKK------------------------------------- --------------------------------AAKK------QAKKE------------- ------------------------------------------------------------ -----------------MKNVSLIIMEPGIQ----------------------G------ ----NIGAIARSMKN---FGFSKLILVNPKCEVGEEARKRAKNAQDILRGVKIKKNLSEA TKGFKLVIGTTSR----TGKDYNMP------RSPLTLDVAAKKIVGSNAKTAILLGSEDQ GLSTETLKNCDY-TITIPSAPKYRALNLSHATAIILYEL-S-KAKNSMIIMEAHKHASPR EKEEILKQLKRLIDKTRFRTEHEKKTQEVAWKKIIGKAHPTKREAYALIGFLKKQK---- ------------------------------------------------------------ ---------------------------------------------MKQKTT---YTVRHR RRREGRTDYKKRLELL-KGRQDRLIIRKTNKHIIIQLVKYAHDGDIVLLTASSKEL-EKK GW----KHSLKNLPASHLTGLLAGKKAKEK-KVATAILDIGLYSPLKGSRIYAALKGVID SGLKVPA--GKEIFPG------EERLKGGHIAKYLE------------------------ KHKSITQDYEKIKSEL------------LK------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKSI-SASIPKCLPHGALVETCDNSGA KVIRIFGVKG--HKTVKGQMPSARIGDMVKASVIKGRPDMRKT---VVLAVIVRQKKEYT RPDGTRVKFEDNSAVVVKDDK-GNPKGTILKGPVAKEACE-RWPGIAKISSMIV------ -----------------------MSTKQ-------------------------------- --------------------------------PLTVRGRKFTGIVVSDRMSKTVTVSWER KKYIPKYERYEKRRSKAKAHNPESIN--AETGDLVEIEETRPISKTKHFIITKI------ ----------VK---------------------------------------------KKS ------------------------------------------------------------ ------------------MVQGKLVHFDEIRNNNWKSLFLFLVFMLLIGGMGLLIGLI-- ----------------------------WGNLYFGLILALVFGFAYALIAYYS-GGNM-- ---LMALAGAKPVTKQEYPYLYHTVE-----------------GL-ALAAGVPTPKAYVI NDPAPNAFATGRDPNHSAVAVTTGLLEKLNREELEG-VVAHEM--AHIRNYDIRSMM--- ------IAAVM----------------------------VGIVILLSDF--LL----RSF LWGGMRGGNRDGRAQIIFILIGLA-----LAILAPL----------------IGE----- ---------LIKLSISRRREYAA--------------------D---------------- -------------AGAAVLTRNPRGLANALRKISQDPNELRNTNKATAHLFISSPFKKKK -----------------------------SWLRNLFSTHPD------------------- ----------------------------MNDRVKR----------LEAM---???????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- -MKS--EFSRT-----WKSSTQPRKQRKYAHK-APLHIKSKF-LNTNLSKALRQKH---- ---------------------GKR-SIRLRTGDKVRILRG--TNK--GKEGKIDEVNVKQ AKVYVSGIEKTKKDGS-KIRLP----------LKPSNLQIVELKID-------------- ---------DKK-RKQ----------------------------------KLLTKD-K-- ------------------------------------------------------------ --------EEKKNG---------------------------------------------- ----------------???????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????----------------- -----------------------------M-SLN-DPLANVLSHIYNYEKLGKKELVTAN NSKVIKEVLRIMQEEGFIGSYEELDHGKGGKSLKVHL----------------------I GSLNKCGAVKPRFKVKISDYEKYEK--------------------RYLPAMDFGVLIVST SKGIKTNTQAKKENLGGSLISYAY------------------------------------ -----M------------EDNITAPENCTITQEKI-----FVLAK--GPRGELKRKLT-D K-K----VIVKQ-EGQE-VKLA---YP-GET---KKAKRLLNTNKAHIKNMLKGVNEG-F TYKLKICSGHFPMNVTLK---NNV--LE-VKNFIGEKVPRALKIN--SEAKVNVSGD--- ----EITVEATSKEVAGQVAASIEKLTFRPG---FDKRI----------FQDGIYITEKA GKKIIH------???????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????????????----------- ----------------------------MIKMS---------------------DKMKEI RVEKITLNVGAGKDQKLLEKGIKLIKNL-TGV-EPVKTVTQ--K--RIQGWGLRPGLPIG VKLTLRGK-QA-DEMIKRVLYAKENRLNESCFDDHGNISFGLPEYVDIKDAKYDTEIGMM GLQVSITLARP-GFRVKHRKVRNAHIPARHQIKQEQAIKYMKEKYSVAV--GEE------ --- >GCA_018819225 -----MA-RRIK--SHKRK-HYGNR--TFGHGNKKNWR-GKGSRGGTGR-GGYHKQNWMR TLK-------------------------------------TE-GP---RQTAS-GFVNPT TRRI------IA-----V-PLTHVST----RIE-----KGAFKQ----------EGNAYN ID--LTRKG-KLVKVL----GNGAFSYKA-HVKA---NAFTGSAKVKIEKAGG--SVL-- VAQ--------------------------------------------------------- ---------------------------------------------------------MAI E--------------------KKFLQKSVDQELV----------------KEYLEEAL-S HAGISSITIQ------KTPLATRIALRVRRPSVVIGKKGANIKSVSEELKRRFHIDNPQL DVM-EVNNPTLDAKLI----------AERIGRQIEI--EGKIKQIIRFNIRDIMNAGAYG TEIIVAGK-IV----------GKG-------------GKARTIRMR-------------- ----KGYLKKSGDVM-KLVETAKFTAYGKAGAIG-------------------------- ----------IVVKIL---------------PPGV----------VFPDSV--------- ------------------------K-IDY------------EKLKTIGLTETVEPTVDA- ------------------------------------------------------------ --------EQEKME-----------EEKQAAV---------------------------- ---------------------------AKLKKKM-------------------EQAKKAA RPKKMLRA----------------KSRKP--------KAAMGVH-LPEG-----HVPQI- ----LTARDEPPKDAKKVEKTVETEK---------------------------------- ---DSKTETSDTDAA--------------------------------------------- ------------------------------------------------------------ ---------------------------------------------MTKVPIISLNGSSAG EAELPEQFNE-ACRPDLVRRAVHAEQSRRFQPKGNYVYAGMENTAEYYGRRH-G---WRQ TINTGRSRLPREKLP--GGRLGRV-LRVPQAAKGRRAHPPK-----PWKRIIERINLKER NFAIRSAISATTNLQEVKKRGHEFEG-----SLPLVVENGLEQISKSKDALIAF---EKL GLKKDLQRARDR-RRMRSGRSRLRKGGYRSPKSVLVV-I-G-EDKG-------------- -----IWKAARNFPGVDVVKVNELSAETLAPGGHLGRLTVWTSNA---VSQLEKYSLFM- ------------------------------------------------------------ ---------------------------------------------MTEATGAI-FDVHFR RRREGKTDYVKRLHHL-KSRKTRLIVRRTNRFIIVAFAQYDPKGDHIIVSRTSKEL-KKM GF----DGKC-NVPSAYLTAYWCAKEAQKK-NVKDAILDMGLHAATKGNVIFAALKGAVD GGIAIPM--GNDIAPS------DDRIKGKHLNE--------------------------- ---TLQNQFDESKKKI------------DAS----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MLGM-PARITKALTTKSRLICDDNSGA KIVEIINVKG--AKARARRYPKAGIGDIVMVAVKKGKPEMVKR---KELAVIVRQKKEFR RGKG-RVKFEDNACVLIDDQ--NLPKGTEIKGAIAREIAD-RFPKVVAIAASVV------ ------------------------MAKEIT----------PSPE--KK--ASKTEC---- -A----DRRCPK------------------HGGLKTHGRIFEGVVSSTKAPSTASIVISF HRKVPKYERLEKRRSKLHVHIPACRT--VKEGDRIKIMETRKLSKTKNFVIID------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MARKFSYKGHSIE--------------------ELQNMPFEQFMLLV NSKARRSLRRM-------GYKIKKLLLKI---KNAKPN-------KIIKTQ-VREMV--- ------VVPQM----------------------------VGRRFQVYNG--------KEY M-----------EVLIRPEMLGKR----------------------------LGD----- ----------FSHTI-KLVKHSG------------------------------------- -------------PGIGA-TR-------------------------------GSKAVELK ------------------------------------------------------------ ------------------------------------------------------------ ------------MNRARIKLESKEYTDLDAVCVQIKDIARKAGVELKGPIPLPTKKLRIS TRKTPCGDGS-------DTYEKWEMRVHKRLIEI-KADDRVLRDIMRIRIPDSVHVEMLL N----------------------------------------------------------- -MKL-----------NATITKQPRKKRKAFYQ-GGLHLKQKS-IHVHLSKDLKKKF---- ---------------------NKR-SMLAKKGDTVRVMRG--TFR--KREGKISSVDTKH VQVFVEGVIRKRQAGQ-EVLAA----------FHPSNLVMSEYQEP-------------- ---------KHK-IKKSKK-------------------------------KAVKQETA-- ------------------------------------------------------------ -----SKLEMKR------------------------------------------------ --------------------------------MG-LRPARTVREY--------------- -KGQPWARISVKRP--RKSFVKGA-PRPKVRQYNMGT-----DQFYEI-QVDMISDEDI- -QLRDNAIESARQVTGKYL-EKNLPNN--YFFGILKYPHIVIREHSALG-VAGADRISKG MKMAFGRPKGRLARIGK-GEPVFRVRVA----ASALPVVKEAIKRAKIKMSGAYHEEVKD IQNEAFNRAKIGKVIV---MKK-----VEEIK-PKAPAV-ETA------PAEGE--EKKD EKAEGK------------EEKKAEVKEEKKK----------------------------- -----------------------------M-DMT-DTLANVLNTMKVAEIRGKQDTLVRP ASKMIRSVLEILKEEGYIDEFELLNNGL-DGEFSVKL----------------------S GKINACGAVKPRFPVKTSDWEKYES--------------------RFLPAKGMGILLVST SKGIVTHQKAKEQNAGGRLIAYVY------------------------------------ -------------------MILELPSNVSVEVQGM-----RIAIK--TPKGEATVKFN-- -----TRFT-SV-KKNE-KGLEILPAR-KEN---RASKAAMNSFKKHIQNAIQGLETP-F QKKMRIIFAHFPISIEVK---GNE--IL-VKNFLGEKVPRVAYIQ--GNTKVEIRGQ--- ----EVIVSGNSKDDVGQTAANIRKSGRIRR---KDERV----------FQDGIYYDE-- ------------------------------------------------------------ ---------------------------MGKRTGPKHGSRSYWHRKRAAKLVPRMRSW-S- Q-------KGKGLTGFLGYKAGMGQVLMTEDR-NSPQK--NQEITRPVTFIETPPIFIYS AIGYVET--LDG-LK---TKSEVAVSNPPKQ-----L-----QRSM-------------- ----TVA---K--------KPKQT-----------------------PEDFEKH------ ---VA--DFQEVRVLACSQP-----WKAGL-KQTPDVFELAVVGKDSK---EQWDFAKTI LGK-EVPVSQVFADGEFVDVIAVTKGKGWQGVVKRFGVSLNIR--KATKKRRH--GGSL- GPER-QGKVM-YTIPRAGQMGFHRRTERNKRILKIAQP-AEAE--KMTPKGGFTHYGTLA NEFLVVDGSIPGPVKRAVRLRRALI---EQH------ILKP-DLKKFVV----------- ------------------------------------------------------------ ----MGLYKYSFK---------------------------------------A-DDRETA R----------------------------------------------------------- -----------AQAFDLD-ASYKDMSQVLRAM--KGLSIKEARKVLDDIVSKKQPIAYKK FNK-HMSHRS-----Q----LGGKKGRFPRKEAIIVLRLLKNAEANANYRGL-NVDEMIV RQGAAYKQNVLRRYRRVFVNPTVLGYGK--QALWANYVTCRAEITL-------------- ------------------------------------------SKGISRKAKRKQ------ ------------------------------------------------------------ ---------------------------------------KY--------QKKK---KV-- ------------------------------------------------------------ ---------------------MGSKITVQK-------------RGHGSPAYRTPKHRFL- SKAKY-------PPIHKNLRAQ----VLTFEQDPSKDVLLAKLLLDDGRV-VHVLAAEGL KTNDEVFMGP-------------DAK---LDIGSVVPLERIPDSSSVFNLEIAPKDGGRI ARTSGSFATIVSH-DEELG-LVTVRLSSKQVLKLDPNCMATIGVASGGGRTEKPLKKAGT GRAKWKARNKRWPVVRGSAMNAVDHPHG-GRSM------G-K----PSTVSRNAPPGQKV GHIAASRTG-------RRKGKMKVGDNKAR------------------------------ -------------------------------MN----------------------PMEAV RLEKVTLNIGIGGAGERLDQAKALLERI-ANR-KSIYTRAK--A--RNSTFKVRKGQPIG VKTTLRGT-NA-KEVLTRCLETLDNLLRTTNFDRFGNVSFGIKEYIDVPGLKYDPKIGMM GFDVSVTLAKP-GKRVSRRRIAKRRLSMKQRVTPQEAKAYVETTYGVKV-EEPEEEE--- --- >GCA_003599055 -----MV-VKKR--RKSSR-MLGTN--TYGWG-KNKHR-NSGSRGGFGN-AGTGKKSHNK K---------TKVWA----------------ED-----Y-F--G-------KF-GFVRH- -----GQS--NA-D-VAI-NVRDVEG----RLSGWVA-QKQA-SR---------EGDVFV VD--LTKLG--FTKLL----GAGRVSTKM-RIVI---QNAVKSAKEKVQQAGG--EVV-- V--------------------------ETK------------------------------ ----------------------------------------------------------MI E--------------------RKFVAEKLKEYQI----------------QEFIAESL-K NVGHSHTKLQ------RTPVGDKVVIFASRPGLVVGRKGENIKKLTQTLKKRFNLENPQI EIS-EVQNPNLDAQIV----------AERIASTLERFGIQKFKAIGHKTMTDVINSGAMG IEILISGK-V------------PS-------------QRAKTWRFN-------------- ----QGYLKKCGEIAIEGVKHAKAVAVLKTGEIG-------------------------- ----------IQVSIM---------------GPDV----------QLPDDI--------- ------------------------------------------------------------ ------------------------------------------------------------ -----------EVR-----------RKEEAPE---------------------------- ---------------------------GEAQ----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------M-MTVKVLDKESKEVG MQKLPSQFQE-PIRVDLIKRAVDSVQSRKRQIYGADPRAGKKQAAKLSRRRR-D---YKG AYGKGVSRMPRKTMTRRGMQMMWVGAFAPGTVGGRRAFPPS-----SERVFAQAMNTKER RKAIRSALAAVMNKELVSGRGHAVP--Q---NYPFILASDVESLAKTSEFEAML---LKL GLEGDLERGGK--RAVRAGKGKARGRKLKKSKGPLIV-V-S-GACK-------------- -----MLSAARNIPGVDVVEVRKVNAELLAPGAHPGRLTLMTQAA---VQKLEKEGLFL- ------------------------------------------------------------ ---------------------------------------------MATNNT---YSVPYR RKREGKTDYRKRLKML-TGSAPRLVVRKSLRYVVLQVIEFSPSGDKVIVTAHSKEL-AKF GW----KADGANTSAAYLTGLLIAKKLKKK---MRVLVDLGQNVSVKGSVLYAAVKGAQD GGLDVPC--AKEVLPS------DDRVRGEHVAKFAKALKAQKD-RYQVQFAKYIK--SGV EPEQLPALVDQVKSKI----------GGAV------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAV-KARVTKGLPHTANVVACDNSGA RILRIISVKT--AKTVKGRKPSAGVGDYVMCSVVEGRPDMRKQ---VVPAVIVRQRMPYR RKDGTRIRFEDNAAVVLKDEM-GNPKGTMIKGPIAKEASE-RWPMVSKIASIVI------ -------------------------------------MK--------------------- --------------------------------SVRTRGREFTGVVTETKMQLTATVEWPR RKYVSKYERYATAKTRVKAHNPPEIN--AAAGDVVKLVECRPISKTKHFMIVEK------ ----------VG-HERLF---VAKQELMEESK---------------KKQKKAE-ETEDE SS---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------MAKEFYFHGKTAD--------------------ELKKMSLEDFAQLV PSRERRKIKRGF------TDAEKKLLEDIRSGGK------------AVKTH-CRDMI--- ------ILPEM----------------------------IGKSIKVYTG--------KEW V-----------EVLVEAELLGHR----------------------------LGE----- ----------FAQTR-KQVRHSA------------------------------------- -------------PGIGA-TR-------------------------------SSASLSVR ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLASVDIDKLNTTCAFIKDISDKTGVQMRGPIPLPTKRLKLA TRRAPGGRGS-------ATWERYEMRVHKRMIDL-GLDERALRLVMRIPVPDGLNIEIEM IDA--------------------------------------------------------- -M----TWSSS-----WKGSRKPRRQRAFVRF-APAHVKSGL-LGSHVAKALRAKV---- ---------------------KAR-SLRVRKGDTVKVMRG--QYA--GKSGKVSRVDVKN MHVFIEGVEFTKRDGS-KGFYP----------VHPSKLLITDIEGK-------------- ---------DKR-RLGGS--------------------------------Q--------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MARLRNWTCYRDL--------------- -K-RAYTRFSKYK---KLCYVRAR-PANRISRYTGGT-----QERYQF-DVHLVAGETL- -QIRDNALESARQVSNRAL-EKVLAKA-GYFIQMRVYPHHILRENPLAA-GAGADRLSTG MAHNYGKPIGLAAQIKK-GQPIFTVKT---N-KENVPLARRALKRAMYKL--PCHCSV-- ---------------------V-----VKTIEQPPQMKAIK----------ASAKAKAVA A----------------------------------------------------------- -------------------------------MLN-DPLANVMSAILTYEKTGKRELIVHP VSKLMRKVLAIMQAHQYVGALDDVSEGR-GGFAKLHL----------------------L GNVNKCGVIKPRFSVQNQGFIKFEK--------------------RYLPASGVGILILST SQGLMTHVEAREKGIGGRLIAYCY------------------------------------ -MKLDI------------HDETEMPSGVTVGYKDG-----ILTIT--GPKGEVSRPLR-D P-R----LAISA-SGDT-LLIA---CE-NAS---RREKRMANTFNAHVENMIAGVQEP-Y RYKLKICSGHFPMNVAVQ---GDQ--FV-VKNFLGEKFPRVLKLK--KGAVVKVEGE--- ----FITVESCDKDLAGRIASDIELLTAKRN---RDLRV----------FQDGIYMIEKA NQKLEAS----------------------------------------------------- ---------------------------MPRIRTPRQGSMQFWPRSRASDIVARVRNW-P- A-QK-----DVKLVGFAGYKVGMTHVLLKDNKPTSMTK--GEEISVPVTVIECPPIKVAS VLLYKKD--AYG-LH---CVGQINAEKVDGE-----L-----GRVL-------------- ----AVP---K--------K-PAK-----------------------QVEAK-------- -------GLDDVRVLVYTQP-----KLSGLGKKTPEVFELGIGGAKAE---EKLAFAQSI LGK-EVKLSDVFAQGQLVDASAVTKGKGLQGPVKRFRIALRSH--KSEKTKRG--PGSL- GPW--HGFRG-FRVPHAGQMGFHQRLEHNKHILMIGD---DPK--KVNVKGGFLRYGNVK SQFMLVKGSVAGASKRLVTFSSARR---A-HLVKLP-KDAP-EITYVSVSAKQ------- ------------------------------------------------------------ -----MAYQYAV-----------------------------------------KETGNAA R----------------------------------------------------------- -----------AVGLALP-ISRKQSVMICQSI--RGLAVPKARKLLEDVIAMKKPIRFTR FNG-DMGHKA-----G-----MAA-GSFPVTACKQILMLLKSAEANAQFKGL-STAGLMV RSATAHKGPTAYHF------------GR--QRT-KAKR-THVELVL-------EEGKK-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKSLIQQA-------------RGKGGPVYRARSFAYA- GDVKMR-NDPAELVS-----GT----VTDLIKCPGHTAPLMEVKYEDNVT-ALLPAPEFI RVGDRVQCGK-------------GAN---AENGCATQLRYLPEGTQVYNIEAQPGDGGRF CRTGGSAARLIAK-TD--T-YALILLPSKKEKMFNLDCRALVGIVSGGGRLEKPMLKAGN MHHNRRIKNKRWPNPSGAAQNAVDHPFG-NKRTSRK---A-K----QKAASHFAPPGRKV GKLWPRKTG-------RGK----------------------------------------- -------------------------------MN----------------------VMQLP RIEKVTLNVGAGKDQNRLEKGVTVLKMI-TGI-EPMKTVTQ--Q--RIPTWGLRPGLPIG CKLTLRKA-KA-VEVLKRLLVAKENKLRLTQFDNAGNVSFGIHEYIDIPGVTYDPKIGVL GLQVCVTLEKP-GYRVKRRRLKTRPVPKKHMVSREEAMAFMQKAFGVTI--GEKA----- --- >GCA_007116315 ----MRT-ARTR--KKNTR-QHGGT--THGYGSMKKHR-GAGSRGGRGN-AGSGKRGDAR K---------PYFRVKL--------------KK-----E-L--G-------KF-GFSNN- KYRT--TY--SP-----V-NVYYLEN----SFLSLKA-KGYF-KE---------KDGLFH ID--LSKLG--FNKLL----ATGKPTRKY-SILV---DYASESAVEKISKAGGIVEVK-- Y---------------S-----------SKEEQESAEE---------------------- ----------------------------------------------------------MI E--------------------RKILHTKLRDYQI----------------DELLAESL-S KVGFSSSKVK------KTPLGEKITIMASKPGLVVGRKGSNIKNLTKILKNKFKLENPQI EIE-EVSNQNLDPQII----------AEKIQSALERFGTKKFKGIGHKSIEDVMAAGALG VEILISGK-I------------PS-------------QRAKRWRFY-------------- ----KGYLKKSGDIAVSQVATAYTAANLKSGTVG-------------------------- ----------IQVRIM---------------LPDT----------WLPDRV--------- ------------------------D-V------------LPKEEAEI--VK--EI----- ---------------------------VEES----------------------------- ----E---LVDEAD-----------ESGDSDQ---------------------------- ---------------------------EEVEE---------------------KDSEEKE PEEKE------------------------------------------------------- -----------VVEKEPTKEHSSK------------------------------------ -----EKDSKEESESKESES---------------------------------------- ------------------------------------------AEKK-------------- ----------------------------------------------MKLKVKDVKNGEKG SVSLPRQFSE-EIRLDLISRAVHTIASHKRQPYGADPEAGKKSSAELSRRRR-K---YRG SYGHGISRVPRKILSRSGTRFNWVGAFAPGTVGGRRAHPPK-----AEKIWALKINNKER QKAIRSALAATIDKDLVVSRGHRIP--T---DYPFAVSEDFEKLAKTKDVLASL---KNI GFDDEVERCKD--KTIRAGKGKLRGRKYRRKTGVLLV-V-S-EQCP-------------- -----LELSAANLPGIDVVKVNELNASLLAPGTDVGRATIFTENA---LKVLEEQDLFYP KTRMLKEVVKITKKA-----------SKAALSSVKKKEAKKVNGAGRS------------ KATKE--TKETKETKE-----------------------------MVNGKN---KALQYR RKRLGLTNYSSRLGLL-KSGKPRMVIRKSSRYLMIQLVEYLPDGDKVLVSVSSKSL-SEL GW----KFSCKNLPAAYLAGFMFGKKAIEKSKV--AIVDIGSLTSKKEGVLYAAVKGAVD AGMEIPV--SDEVLPS------EDRISGKHIAEFGKKLEKEK---YNKLFSGYNK--DKL SVDKLPEEFEKIKVKI------------K------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKSL-KANVTRGLSHGSVLDTCDNSGA KTIKIISVRN--LQTVRRRKPQCGVGDLIMASVVKGRPEMRKQ---VVFAIVVRQKKEYQ RPDGTRVSFEDNSAVVLKDEK-GNPKGTIFKGPIAKEVAV-RWPAVAKVASIIV------ ------------------------MEKET---------R-KS------------------ ---------SLG------------------LENVNVHGRSYVGTVTSAKMASTVVVSWKR RVYVPKYERYAVKTSKVKAHNPDSID--AKEGDIVKIVQCRPLSKTKNFMVVEKLDSL-- TESSVDAKVEVK---------------------------------------------KEE KKPSKK--AETGSDKK-----KSAEKKND------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFAYRGKTLE--------------------ELKSMSINDLALLF KSRIRRLIKRGF------TEEEKTFLSSLENSKG-----------KPVKTH-CRDMV--- ------ILPTM----------------------------VGKNIMIHSG--------KSF V-----------SVIIQPEMIGHR----------------------------LGE----- ----------FSLTR-KRVTHSS------------------------------------- -------------AGVGA-TR-------------------------------SSTATKR- ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLACTDIDKVNDVCKAITDIAEKTGVSLRGPIPLPTKKLRIT TRKSPDGEGS-------ATWERYEMRIHKRLIDL-GVDERALRLVMRVHIPEGLNIEIEL LDVD-------------------------------------------------------- -MNS--KFSKS-----WKSSVQPRKQRKYVAN-APLHTRKNQ-LSVHLSEELRKKY---- ---------------------GKR-SCLVRKGDKVKILRG--NYK--GKEGVVERVSYKD YHVNVAGATYPKPDGN-TSFYP----------IDPSNLVIVELDIA-------------- ---------DSK-RK-----------------------------------IALERK---- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MAKLRKFSAYRRR--------------- -ESRPYTRKSKYR---EKSFIRAS-PTCKVIRFDMGNL----RDSFEY-AVHLSVNSSL- -QIRHNALESARLTSNRTL-EKSLGKS-GFYLKLRKYPHHFLRENPLAS-GAGADRMSTG MKCAFGKIVGMAAQFKP-GDRIFSAYV---N-SSALSVAKSAMNKASKKL--PCSCKI-- ---------------------V-----VEKIVTSEKPTVVEEVVDDVKESVEDKSAEETP --IEAKPEPVEEAQDEVVAEKGAEESDEPKKTEEDVMA---------------------- -----------------------------M-SLN-DTLANSLSYILNLERIGAKECVIKP SSKVVKKVLEVLHESGYIGEIVESETTK-GKQLNVSL----------------------I GRINNCNVVKPRFSVSLDSFTKFEK--------------------RFLPAKDFGVIIVTT NQGIMTHNQAKEKHIGGKLLAYCY-----------------------------------M KMKANI------------DYKLGLPNDVKVDVIGD-----VVKVT--GPKGTVEKKLS-S H-N----VKLGS-SGNE-VSIK---SL-RST---QREKKLANTFRAHVKHMVVGVVDG-H SYKLKICSGHFPMTVTQK---GDI--LE-VKNFLGEAKPRLLKLK--QGVELNIQGS--- ----DITVSSPNKELAGQVAADIEQLTRITN---RDRRI----------FQDGIYIVEKS KSRPIVLEEVSE------------------------------------------------ --------------------------------------MQFWPRKRAKSETVRVRSW-A- K-VK-----DAKPLGFAGYKAGMTHIILTDNNKNSSTK--GMKVRVPVTIIECPNLKVVG ARFYKKT--FFG-PK---VYGEVEFKSDNKR-----L-----SERK-------------- ----NVS---K--------QFKKN-----------------------IDSFS-------D K--LS--DIYDIKLLVHTSP-----EKTSIGKKIPEFFEMGLGGSI-E---EKFAYAKEN ASK-ELSISDVFAPGEQMDVKAVTKGKGFQGPVKRFGISIRAR--KSEKTKRG--PGSIS GGWTSQGHMM-YRVAHAGQMGYHTRTEYNKLIVKVIE---NPE--EINPKGGFVNYGLTK NPCILVKGSVAGPKKRLVRFNKAIR---P-S-KYYA-GFNP-IVDYISLDSKQG------ ------------------------------------------------------------ ----MTSTNYAFQ---------------------------------------EYDEGTMS R----------------------------------------------------------- -----------AYGRALP-ISTKKSVEVCSWI--KGKSLSSAMKMLDDVIAMRKAVPYAR FNQ-ELAHQR-----A----T-GP-GGFPINVAKNVMAILKSAEANASAKGL-NTSSLKI VHICAHLGSRPFRH------------GR--KRRVKAKR-THVEVVL-------QEIASKS ----------------------------------------KSSKSDSKNADSKS------ -----------KVPEKVVEKVANVPV------AKPVEKPA------KEQVSKE------- ----ELKVKESKPEEAKT-----------ESVVADKKETKE--------TTDKTPSEESS -----KD-----------EKEDVKS----------------------EANEPKVDAK--- ---------------------MGKNLIQQA-------------RGKGSMRYRALGFRYK- GSSKH-----KSLGEE-TISGR----IVDFVDCPGHSAPLAQIEFFDGEL-SLMIAPEGM KVGDVINVGA-------------SAI---AEKGNTLPLSKIPEGAFIHNIEGSPGDGGKF VRASGVFAKVSSQ-MS--D-GVVVTLPSKKTKKFGLQCRATIGVVAGGGRTEKPFGKAGT KYHAMKSRNKLYPIVSGNAQNAVDHPLG-NSRSSRK---S-K----NKPAPKNAPPGRNV GMLRPRHTG-------RNK----------------------------------------- ----MIKME-------------------KQIEN----------------------PMREI KISKLTLNVGAGKDQRVLDRSMKLLKVL-TGI-EPVKTITY--K--RIQAWGLRSGLPIG CMITLRDQAKI-RELLPRLLEAKENVMVRKMFDDLGNISFGIPECIDIADYKYDPEIGIL GLQATITLTRP-GYRIMRRKHKSSRINKNHQIKREESIKFMKDNFGISI-KEEIEEE--- --- >Bin50_genes MKTKSQI-EKQIKRKRNIE-LVKTI-------------------------IAAKKDAE-- -------------WFK------------------------I----------AK-ILSSPR RKRI------------NL-NIEEINKK----------------AK---------EGESVV IP----------GKVL----SQGEIDKKI-KVIA---LNFSEKAKEKLLKSKS--EIS-- ------------------------------------------------------------ ----------------------------------------------------------ME E--------------------RNVVKAKKEEFAI----------------RERIKKSL-G KGKISRVRIE------YTPVGEKIIISTNKPGLVIGRSGERIKELTKMLKTNFKLENPNI EID-EIMQPEFDSQII----------ADEIALGLERFGPLKFKVLAYRTLQKIMNAGALG VE---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????-------------MKLQKR RRREAKTDYLKRIKLL-KSGSPRVIFRKTNKYIIAQYVKSKEAQDKIEMGVNSKHL-TKY GWPKQ--GNLKSMPASYLTGFLMGKKII-KDKKETPIVDFGMIRALHKTKVYAFLKGLID AGVKIKH--DESIFPD------ENRIKGEHMKN--------------------------- ---KIP--FNEIKSKIENE----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------MEIQKKQFTYRGKTVE--------------------ELKSLDVREFAKYL KSRQRRTILRQF-------QEIEKFVNRAQEKIKNN---------KKIRTH-KRDLI--- ------IVPKM----------------------------IGMKLQIYNG--------NKF V-----------SVEVIDEMLGHK----------------------------FGE----- ----------FAPTR-GKIKHSK------------------------------------- -------------AGVGA-TK-------------------------------GTRAKAKK ------------------------------------------------------------ ------------------------------------------------------------ ------------MPKVRIKLNSVDIETLNNICNSIRDIAKKSGVTIIGPVPLPTKKLKIT TRKSPCGDGT-------ATFDRFEMRIHKRLIDL-PANEKILHHIMRMQIPKSVNIKIEM KD-------------------------------------------------------MIF IIKV--TTNKEERAVDMIADRVEKKSLNVFSVSRPHGLRGYILLEAEDRESAEEAVFNLP YIKGIIGKTINYEEIKNMIEPSVT-SISIKDGDIVEIIAE--PFK--KEKAKVLRIDKQK EEVVVSLLGA-------VVPLP--------VTVKLDNIKVIRREEG-------------- ---------EGD-EDEY------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MAGLRKATAYSKR--------------- -KVVPYTRVSKKR---QKSYIKTV-PPQKIVKFTMGKEALYNKGKLPY-QLTMVSDEKV- -QIRHNALEACRQYINKKL-EKEFVEQ--YLFKVIPSPHHIQRENKMLT-AAGADRMQTG MQLSFGKAIGKAAILKP-GNRIFLVAV--PN-QKAVQFVRKVFKQIKSKL--PCKTKV-- ---------------------L-----YEKIR---------------------------- ------------------------------------------------------------ ---------------------------------------DGLNVIKNAKKAGKETVKIKI ISNLLIEILKIMKQKNAIKKYKIDSK---RSSVEITI----------------------G K-LLECKAIKPRFKVNKSQIEKYRR--------------------RYLPARNMGTVIISS NKGLITHEEAQEEQIGGCLIAFFY------------------------------------ -MKKDL------------LQEIEIPEGVEANIEGN-----IIIIK--GKEGENKRSFN-M K-N----LTFER-KDNK-IIIS---SK-KAT---KKEKKNMNSIASHIKNMIKGIQEK-F EYRLKVCFSHFPISVDVK---GNE--AT-VKNFLGEKIPRKLQIP--QGVDVQVNKE--- ----IITINSSNKELAGQAAANFERATRIRK---KDRRI----------FQDGIFITNKA GREM-------------------------------------------------------- ---------------------------MPTRRSPRKGSLQFWPRKRASKFLPRV-NW-S- A-INS----GKNLKGFICYKAGMGSAYVKDNTINSMTK--GKKIIIPITILECPPLKIFS VRFYKD-------GK---VSEEVLVENLDKE-----L-----KKKL-------------- ----KLP---K--------VKKGE-----------------------IKNSK-------- -------EYDDIKVICYSVV-----KKTNI-KKKPDLSEIGLVGNV-E---EKMNFIKEN LKK-EISILDVFEKGQLVDLRGLTKGQGLSGPVKRFG----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MTNTEKPTT KAEQKKQGRVSTPKKN---VELAKTPIQPKTE---------------EKQINQKD-EQLT E----E-------------KKPVQK----------------K-----PKV---------- -KRTEAV----VNARGLH-ISTKYSVAICKFI--KNKRIENAITDLEQVLVFKKAVPMKG ----EIAHRK-----G---KGMMS-GKFPKKATENFIKLLKNLSSNANVNEL-D-NPVIV E-AVANLASRPYGR---F--------GR-----IRKKR-SHVKIIA-------REKKMIN ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------KKKK------- ------------------EKKK-------------------------------------- ---------------------MGKRIITQR-------------RGRGTHTYKVRRKAFR- YKLQYP-P---------RIDGE--GKVVKLFNSSAHSSPLAKISCKTGS--FYIPAFKGM VEGQKINLNS-------------NK----IEKGNIVRLKDVPLKTRFNNIESRPGDGGVF IKTAGSSAAINRI-VD--K-DIFVLMPSKKEKKLNPNCRVIIGEIAGAGRLDKPIIKAGK QYHIKKSKSKLWPRTSAVKMNAIDHPFG-SGRAKNV-----K----SKIAKRNAPPGRKV GLLRPRRTG-------KKK------------------------------??????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??? >GCA_007128245 -----MT-ITKR--KKVRK-YRGSK--THGGGSMKKRR-GAGSRGGRGR-AGSGKRGDSK K---------PSYW-----------------KD-----WEM--G-------TH-GFTS-- HSRS--VT--VA-----M-NVSDLHR----ELPRLVE-QGVA-TK---------KGDIYT VD--LSVLG--VDKLL----GAGHIGVSV-SVSV---AAATPKAKEKVSAAGG------- -----------------------------SVVEEASED---------------------- ---------------------------------------------------------MAI E--------------------RKFVDQNMREFRI----------------KRFVEENV-Q RVGLSDVKLK------KTPLGDKIVIHASRPGLVVGRGGASIQLLTRQLKEEFNLDNPQI EIE-EIANPDLDADIV----------AERVLNTLERFGSGRTKSIGHRAMADTIRAGALG VEIIISGK-I------------PS-------------MRAKSWRFY-------------- ----QGYLKKAGDIAVEGVDKSIKSVTLKSGAVG-------------------------- ----------IRVSIM---------------PPGL----------VLPDNI--------- ------------------------T-L------------T-EQLVTE--VE--EVT---- --------------------------GTPEA----------------------------- --------LETE--EI---------AQ-EPAK---------------------------- ---------------------------ETTTE---------------------AETAEVT TQAEP------------------------------------------------------- ------------SAEDTEPKA-EQ------------------------------------ ---SVSEEQSSDAE---------------------------------------------- ------------------------------------------E-KQ-------------- ----------------------------------------------MKLKILNTKNTQNG DITFP--INE-PLRTDLIKRAIQSLRSRARQPYGADPRAGLKHSTNIRKRRR-V---YRG SYGSGIARSPRKILSRNGRRLNWVGAEAPNTVGGRRAHPAK-----ASKIWERKINKKEN RKAISSAITATLDKEVVALRGHKLP--S---TYPFALDADFDALTKTKDVIAAL---ETL GFADDLTRGAQ--GAKS-----------------LLI-V-T-ESET-------------- -----LTKAAKNISGVDVASARQLNAYMLAPGAHPGRATLYTTQS---IKILSGEEPADS TQKSADSKPKAVKKAANT----KPKAAVSKPKAVKKEAKK-------------------- ---------------------------------------------MAKTNR---FNLPFR RRRQLKTDYKKRLALL-KSRTPRLVVRKSNANTVVQIIEYRPDGDVILAQGSTAQL-AGF GW----KASQGSIPAAYLAGYLAGTRALKA-GVSDVIADLGMQEPYHGGRLFAAVKGALD AGLSVPA--SDSAFPS------EERLSGTHID---------------------------- --ESMPKLVEAVKKK-------------VGA----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKPI-TSSVTEAFQPGSQVATCDNSGA KIVEIISVLN--KKTSKGRRSGAGVGDMCIVTVKKGRPDVRKQ---VMHAVIVRQKKEFR RVDGVHVKFEDNAVVVCKDAK-GNPKGTIFKGPIAKEAAD-RWPGVANVASIIV------ -----------------------MAAKKT---------A-KQVA-----------P---- -E----GQDKGS------------------VSTISLRGQEFVGTVVSAKAHRTVSVAWER RRYVPKYERYEKRRSKVAAHNPDEID--AKEGDVVRIKESRPLSKTKHFVVTEI------ ----------LT---------------------------------------------RKQ E----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKVFTYKGKTLD--------------------ELSTLSRDELAALF DSRARRTMMRGY------PEEWKKAEAKILAKDR-------------VKTH-ARELI--- ------ILPRM----------------------------VGKTVLVHNG--------KEF K-----------EVRIQEEMIGQR----------------------------LGE----- ----------FALTR-NNVRHSN------------------------------------- -------------PGVGA-TR-------------------------------SSSAASVR ------------------------------------------------------------ ----------------------------------------------------???????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- -MKQ--TFKRT-----WNKSVQARKQRKYRYN-APLHTQSKF-LHASLSKPLREKH---- ---------------------GRR-SLRVRTGDEVEILRG--SFS--GESGVVEEIDTKR ARLIIRGVAALKLDGS-RKPYP----------VAISNVRITKL-VE-------------- ---------DKR-RI--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MARDRKFVAYRRL--------------- -E-RPYTRKSKYR---RYQYVRGT-PHSKIVRFVMGSR----TKSFPI-SVKLVSKTDL- -QIRHSSLEAARMSANRRL-EKAAGKQ-GYFFRIHKFPHHILRENPLAS-GAGADRLSTG MKKSFGKAVGVAAQVRR-GDVVIEIGC---E-EKHLEVAKRALNIVSSKL--PNGYYV-- ---------------------M-----VDRVPAGSNEVT--------------QTHKRLP KVYE-------------------------------------------------------- -----------------------------M-ALN-NPLANVLSAINNNERVSHKEVTLKN NSKVIRKVLDILQEQGYVSSFEVIENGR-GGELKVLL----------------------A GTINKIGVISPNFPVGKSDYQKYEQ--------------------RYLPARDFGILVVST SKGMMTHMQAKELGIGGRLIAYCY------------------------------------ -MKATI------------QEQVPIPEGVTASYQNN-----VLVVE--GKAGKVERTLI-Q P-G----IAISV-KDNV-VHLD---AP-NAT---QREKRHLYTMRSHIRNMLQGAQEG-H TYKLKVCSGHFPMNVSVS---GDK--LT-VKNFLGEAVPRVLSLK--QGAVVKLDGD--- ----IITVSAPSKEIAGQQAADIEQLTRITN---RDRRI----------FQDGLYIVEKD GRPIL-------PHETTLARIYFHTRTFLKEVVFASCYTHAICVCNTPENRAASLLVHTA SIIGDTTHALSFQIDLSKMG--------KKINHSRHGSLQYWPRKRAARQHARVRSF--- --ASDK---E-GFAAFAGFKAGMTHIQVVDNQKNSPTK--GREINVPVTIIECPPLKIIG VRAYKHN-----------------TKGYGET-----A-----ATEV-------------- ----RLKSNSKHLERTTTWKPTGS-----------------------LDKLH-------- ---PE--DFTRATLIAHTQP-----DLAGFGQKKPQIFEVGFNGS-VA---DTIAFAKE- -HQ-EVTVDKILEPGAFVDAHAVTTGKGFAGVVKRFGVSLRSH--KSEKSNRK---AVI- GPEG-YGKVQ-YTAPQAGKMGYHLRTEYNKQIMAIVEP------DQVQISGGLVNYGQVK NTTLLVKGSIPGPKKRMVTLVKSTR-----QDPKAS-TQPM-EVSHIATRSQQGNN---- ------------------------------------------------------------ -----MGYKYAYQ----------------------------------------GDTQSTA R----------------------------------------------------------- -----------AAQTNVA-VSTKSAIMVANFV--RGKSVERAQRDLGLVLAKKIAVPFTR FTD-GAGHKP-----G-----IGP-GKYPIKASEYMLSAINSAAANARDKGL-G-DELTI VSVTVHQAARQMRY------------GR--LRGRQRKG-THIEVVV-------AEAEEKK ----TRKPATK-------------------------------AKPKAADSTPKAADS--- -----------TPKADTEPKAADSEP-------SAEQEPA----------KKAA------ ----KKS--TPKADTEP--------------KAVKKAADST--------PKAE--KKSEE ------------------KKE--------------------------------------- ---------------------MGKPIIPQK-------------RGKGSPSYTVTSHRFK- GQAKH-----FADG-----EGQ----IVDIIHCAGHTAPLALVEHEQGLL-YLTIAGEGA SVGEIVQIGQ-------------DAE---LKVGNTLMLQDVPEGTPVFNIEGQPGDGGKF VRSSGSAARVVTK-TA--T-HVTVALPSKKQRTFSAKCRATIGVPAGGGRVDKPLLKAGV AFHKYGARNKYWPKVSGNSMNAADHPFG-NTRSMRK---S-K----SKPAPRDAPPGRKV GMIRPRQTG-------RK------------------------------------------ -------------------------------MN----------------------VMKTL QIDKVTINFGAGKDQQRLEKGMQLIQMI-TGK-TPVKTITQ--A--RIPGWGLRPGLPVG LKLTLRGE-EA-KSVLSRLLEARENRLKESCVDNYGNISFGLSEYIDIPGVKYDPKIGVI GIQASITLTRP-GYRVSRRKLRSTSIGKHHVVSRQEAKEFMEKHFSVEF-VQ-------- --- >GCA_018701795 ------M-PHKL--RKVRK-QRGSR--YMGWGQVGQHR-KSGGRGGKGG-AGGRKHFWIR TVK-----YEPE-------------------------RY------------LKKGFLPPS SKVP--KV--KT-----I-NVGELTE---LAMNALTD-YG---IK---------GGN--E LD--LTSMG--IGKVL----GRGKIAVPL-NLKV---AQITSSAQEKIEEAGG--SII-- --------------------------EP-------------------------------- ---------------------------------------------------------MSI V--------------------KRIIKNNIERVKV----------------DELLAKEY-E QAGYGGITLT------KTPMGAQINLYAMRPGRVIGKRGRAIKAASERLENELGLPNPQI TVI-EVEVPELNPAIM----------AARIANALER--GVHFRRSIFWSLRRIMDSGALG CEIILKGP-L------------RS-------------ARSRFEKVV-------------- ----EGYVPKSGEPALRNVRISTLHVKMKRGTLG-------------------------- ----------VTVKIV---------------PPDA----------KFPDKI--------- ------------------------S-LEGLPDI----------EYQLP-MEEPAPV---- ------------------------------------------------------------ ----------TEVP-----------AEAVVD-DTIE------------------------ ---------------------VVESEADAAKPVIT------------DEVA-SEEAPAQ- -EETPVVEAIVDSAVEEAVVEE-SAPVEPVVEEPAVEEVAEAVEVAVEEPVVDESIAEGA TSEKMTETAEPVVEEAAVEPAVEEPVVEA----PEEP-------------VAEE------ -PA-VEKTIDAAEPAVAEEVVVETVVEPVVEESAPVETAVEEPEAVEESQSEPVITESAP EVSEPEAPEEPAAEPELVSEPEPAAEPEVKVVDPEP------EVKPKPE-ADKV-----E EATEDQPEEEKQ----------------------------------MKVPVINLQNEKTG EVEIPQVFNT-PVRHDVIRRAVIALQSTRFQPQGRDPMAGKHTTAESRGTGH-------- ----GIARVPR-LKG------SSRAAFGVSIVGGHAAFPPR-----SEKVIVKRINKKER RFAIRSGIAATAVKELVEKRGHKFE--S--EHLPIVVSNEIQSLKKTKDVESLF---IAI GVQDDVERA-DR-RKVRAGRGKMRGRKHKKGKGPLVV-V-A-EDDG-------------- -----IGYAARNLPGVEICSVAGLNAELLAPGAHPGRLVIWTESA---FGQVDE--VWER ------------------------------------------------------------ ---------------------------------------------MAKGPR---YRTPYR RRRQKKTDYAARRTLA-TSEHPRFVVRISNKTIQVQVTKSEMVGDFVLVKASSHELKEKH GW----IASGKNMPAAYLIGYLVGKKAKAA-GYEYANLDVGLKRVTSGNKIFAVVQGAND AGFEVPF--DSDIAPS------PEAISGKVIADYAKNIEDPFE--YERRFSVYLR--RGL RPEALPSHFEKVKKHI------------EENNDE-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------MSKRIKRR-----------ILP-RRKTSGGLTIGSVVNCADNTGA RKLKIIQMVG--YKGRRRRLPSPGIGDLVIVSCREGTPEMRRQ---LFSAVIVRQRRPYQ RQDGSRIQFEDNAVVILTAE--GTLRGSDIKGPVAQEAVQ-RWSRIGNLARMVV------ -----------------------------M---IS-LKK-PELE-----------C---- -N----DKDCPF------------------HGELAVRGRIMEATVVSTRMQKSCIVQLNY LRYDQKYERYARMRSRIPAHSTTCIP--IKVGDVVRIAECRPLSKTKSFVVVEM------ ----------IK---------------------------------------------EA- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MPKDFNYRGKTVE--------------------ELKAMSMDEFIRLL PSRMRRSLRRGL------SAEQRIVLEKLR--RDKG---------KPVRTH-ARDLI--- ------ILPDM----------------------------LGKTIHCYTG--------KEF R-----------EVVINQKMLGHY----------------------------LGE----- ----------YASPM-AIVRHGR------------------------------------- -------------PGIGA-SR-------------------------------SSMYIPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------ARRARIKLTSTDAVKLQDVCDEIKDIAKRIGVKLVGPIPLPTKKLVVP TRKTPCGDGS-------NTWDRFEMRVHKRLIEI-DARDRVMRSIMRIRVPNEVYIEMEI R----------------------------------------------------------- -MKN--------------KVTKPSTSRRNRYN-APNHIKRKF-ISAPLSPSLRAEY---- ---------------------GTR-SMPVVVDDTVSITKG--DRK--LAEGKVLRVNSGD CKIYIEGVTRARQDGS-TVQIP----------VRAENVMITRLNLD-------------- ---------DQW-RK-----------------------------------DILERKGF-- -----SAEA--------------------------------------------------- ------------------------------------------------------------ ------------------------------------MKAADYKYK--------------- -KNHAYTR---------KKYMGGI-PGSKIVKFTMGNT----SREFTH-RVELINIKYV- -QIRHNALESARIAANRVL-EKNQGRE-NFMLKIIPYPHQVIREHKRVN-VAQADRFQEG MKRAWGKPTYVAARIAK-LQPVIIAEV---D-KDGIADAKEALKRASAKF--PTKCRI-- ---------------------V-----VKEL----------------------------- ------------------------------------------------------------ -----------------------------M-IMM-DPLVNALNTILAHEGRRKGECIITP ASGIVGRVLRLIQSKGYVGEIEYIDDGR-QGKFRVQL----------------------F GRINSCEAVRPRYKTRVSELEKWEK--------------------RFLPSRNMGFVILST PKGVMDHVQAKEENVGGVVLAYVY------------------------------------ -MTVQIV-----------EQTVTVPEGVNLTLNGH-----KVAVT--GTNGAIEYDFG-H A-G----MNLNY-QESS-LRVW---VE-NPR---RKQAALVKTIASHVSNMIKGVTEG-F TYRLKIVFIHFPMTINVQ---KEK--VI-INNFIGEQAPRVAKIR--GQVEIRQDGD--- ----DLIVTGADINHVAQTAANIQESTKIKN---KDLRK----------FLDGIYVYQKE ------------------------------------------------------------ ---------------------------MPRVRSPKRGSRGYSPRKRARNPKGRVSYW-P- K-LDG----EPQLAGFAGYKAGMTHLFYIEDRQRVPEY--GQEVKAAATVIDTPPMLVVA IRAYKKT--QDG-LQ---AITEAWMQNQPRD-----L-----HRRI-------------- ----TFA---TDP------QPESK-----------------------INEITEK------ ---IS--KVAEIRVIAATQP-----RLSSLSQKAPDLFEIPVSGGSME---SQLEYAKGL LGK-TVTIKDVFGPSEGIDIIGVTKGKGFQGPVKRWGIRILAR--KARKSRRA--VASI- GPWV-PRRVM-PQVPRAGQMGFHNRTEFNKRIMLMNG---DTD--RINPKAGFKNYGFVK GDYLLLKGSIIGSAKRLIKLRKTVR-----D-TDYP-EEAP-QITYLHTEWTKGGIQQ-- ------------------------------------------------------------ ----MPSWKYSVQ---------------------------------------GLDPDKTA I----------------------------------------------------------- -----------ASGRDLR-IKPKTSREICNTL--KGMKLDEAKTFLNDVIDKKRAVPYYR YRG-KTPHRK-----GLN--GHDA-GRYPEKAAGEILKILDSVEANAEFKGL-YADRLRI VHMAAHKARVIRKFIP-------RAFGR--ASPYYKHL-THIEVAV-------EEY---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKKLRVQR-------------RGRGGHTYKAAKMNKK- APSKYP-VIT-----EEVLQGF----VKSMEHEPGRGAPLAYIEFAPGHG-YHVAATEGL SLNMPIMVGI-------------GAI---PKVGNVLHLKDIPEGTMVSNIELRPGDGGKI ARSSGSFATVIAH-ID--D-YTTVRLPSRRIIRVKSNSRATIGIVSGGGRLERPFMKAGE KHHKKKAKGHKYPTAHGVKMPAAMHPHG-GGRHRRP---G-K----STTVSRHAPPGAKV GLIAARNSG-------RRKRTRRN------------------------------------ -----------------------------MSQN----------------------VMKQI KIGKVVVNISVGQSGQPLANAMKILTDI-TGQ-NPSQRLAK--M--TIRPWGVRKGEPIA CAVTLRGD-NA-DAFLQKAFIAVRHKINPRSFDKEGNFAFGIREHIDIPGVRYDPATGII GMDVMATVERS-GYRVKRKKRGQSKVGSSHRVTPDESREFVSEKYGVTM-GLE------- --- >GCA_011363855 ------M-PHDL--RKIRK-KRGSR--TCGYGRVGQHR-KSGSKGER-R-AGRHKHLWSW VLR-----YEPD--------------------------Y-F--G-------YK-GFTSPK QLRR--KN-IKC-----I-NVKELEE----IALKMAT-Q----VG---------EKEKII ID--LEAMG--YLKLL----GEGKITMPV-IVKV---PSYTEEALRKVREAGG--EII-- S--AK------------------------------------------------------- ---------------------------------------------------------MAY V--------------------KHFVKESIRKAEI----------------DEFLWKEF-E RAGYGGVEIT------KTPLGTNVVIHAVRPGLIIGRGGETIKNLAKILEEKFNLPNPQI SVV-EIEVPELNPRVM----------ASRIAAALRR--GIHFRRVGFWALNQIMRAGALG AEIIISGK-L------------RT-------------ERARSEKFR-------------- ----SGYIPKSGDPAMKYVRKAVTHVQLKPGIFG-------------------------- ----------IQVFIV---------------QPDV----------KFPDEV--------- ------------------------E-F---------------LE---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------EKSGET------------------------------------ ----VAESGEDKS----------------------------------------------- ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????----MAKGPA---YAVPYR RRREGKTDYRLRKKLI-ISKIPRLIVRKTNRNFIVQIAIATVIGDVIITSAHSRELRKTF GW----LGSLNNLPAAYLVGLLCGLRASEK-GVKKAVLDIGLHTPSKGAAVFAAMKGFID AGVEVPH--DESILPD------ESRIRGEHIAKYAELLASTDKEKYERYFSEYLS--RNL PPEKLPEHFEEVKERI------------LESFKSK------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------MAAKAKTRGL-QAKG---AGRP-RIRISRGVNVGSIIKCTDNSGA KELRVIQVVG--YKGRRRRVPAAAVGDLIVVSVRKGAPDMRKK---IFHAVLVRQRKPYR RAEGIWVQFEDNAAVIITPE--GEMRGSEIHGPVAREAAE-RWPRIASAASIII------ ----------------------------MS---YK-INP-PDKT-----------C---- -D----DEYCPF------------------HGSLKIRGRILEGVVVSAKMQKTVIVRRDY AHYEPKFKRYERRHSRIPAHNPPCIN--ATKGDVVRIAECRPVSKTVAFVVVEK------ ----------IG---------------------------------------------RKE EY------------------------------------?????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- MVKS--------------TSAKPSKQRERLYN-APYHLRGKI-MSAHLSDDLRKTY---- ---------------------KVR-SLPIRTGDVVRVMRG--DYK--GVEGKVTRVDRKK YRIYIEGITRQKVDGT-TVPVP----------IHPSNVEIIKLNLD-------------- ---------DKI-RR-----------------------------------EILERKLS-- -----GRSKAIEAALKA------------------------------------------S STPGGG------------------------------------------------------ ----------------???????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????----------------- -----------------------------M-N-M-DTLANGLTTLYNNEVRRKKECYIMP ASKLLGNVLRVMQMHGYIGEFEFIDDGR-TGKFRVQL----------------------L GRINKCGAIRPRYSFKAKDIEKWEK--------------------IYLPARDIGILIVTT SRGVMSHIETKKMGIGGKLLAYVY------------------------------------ -MLEELYE-----VAKIEKREIKVPEGVKVNVNGR-----IVEVI--GPLGKITRDFT-S N-P----VSIEV-LGDK-VVVY---TI-WPR---RREKSHVGTVAAHIKNMIRGVTKG-F TYKLKIVYAHFPISVKVD---GSR--IL-IENFMGERTPRIAKII--GGAKVIVKGD--- ----DVIVQGINLEEVSQTAANIEQATRIKE---RDPRR----------FLDGIYVYEKM EGLVS-------???????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????--------- ----MSEWGYSIV---------------------------------------TYDRATMA R----------------------------------------------------------- -----------ASGRELR-VSPKAAIEICAAI--RGMMLEEAKKYLRDVIAKRVAVPYRR YKK-KLPHRR-----GLG--G--A-GRYPVKAASKILEVLESAEANAEYKGL-DTEKLKI IHASAYPGAKIRRYMP-------RAFGR--ATPKFETL-CHVEIVL-------QEVK--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------?? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????????????----------- --------------------------------------------------------MLKP RIEKVVVNCCVGRSGEPLEKAMKIIEEL-TGQ-KPCYRRAK--K--TIKDFGIRRKEPIA CLVTLRGE-KA-IEFLKRALDAVGNKIPISSFDKFGNFSFGIEEHISIPGTKYSPELGII GMDVCVSLMRP-GYRVKYRRRARSKLGKAHRLTAEEAMAFMVSEFNVTL-TEEKREKKRR KRK >Bin482_genes --------MTKRTGPTNIH-LKELI-------------------------IELKKNSISH S---------SNFWKR------------------------I----------AE-ELSKPT RERR------------IV-NLSRINRY----------------TK---------ENENII VP----------GKVL----ASGDLDHKL-TIAA---WQFSEQALDKIKKANS--KAV-L ITELVKE------------------------NPKGKGIRIIG------------------ ----------------------------------------------------------MI E--------------------RQIVAQKKKEYQI----------------QEMISQNV-K GSGYSHTKLQ------RTPLGEKIIIHAARPGLIVGRKGQNIIKLTNDLKKSFELENPQI EIN-EIDNTNTDATVV----------AGKIAESLERFGTARFKGIMHKTMEEVMNAGALG IEIVISGK-I------------PG-------------SRAKSWRVY-------------- ----SGYLKKCGDIAINWVNKAKVKAVIKTGVVG-------------------------- ----------VKVSIM---------------PPGI----------KLPDNI--------- ------------------------Q-L------------L-EEKQEI--IE--EI----- ---------------------------KEEK----------------------------- --------PVKEDV-----------EEKPKAG---------------------------- ---------------------------EELKK---------------------KQEKED- ----KKTK---------------------------------------------------- ------------PKKEEVKKETKK------------------------------------ ---TVKKPAKKD---------QK------------------------------------- --------------------------------ALKK------EPKKK------------- E---------------------------------------------MKLSILNITKEEIG KQELPSQFEE-EVRPDLIKRAVISIQGNKRQAYGADPMAGKKSSAELSRRRH-V---YKT SYGYGISRVPRKIMSSRGTRMNWVGAFAPGTVGGRKAHPPK-----AGKDWTKKINKKER RKAIRSAIAATLSKELV-GKNHIIP--D---NYPFIIENKFESLKKTKEVRDVL---KKI GFEKELERVSE--KTIRSGKGKKRGRKYKSKTGPLII-V-S-KDCD-------------- -----LLKAAKNIAGINVIMVKSLNAKSLAPSASPGRLTIWTQDA---VKELGDKKLFM- ------------------------------------------------------------ -----------------------------------------??????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????------------------MKAL-KARVTKGLTQGSEVPTCDNSGA KILRIFGVKG--SKTVKGRMPGAGVGDLVMASVKKGNPDMAKQ---VVMAVIVRQRKEYR RMDGTRIKFEDNAAVVLKDDK-GNPKGTIFKGAIAKEACE-RWPGIAKLARIIV---MKN KT-----------------EKKQTMPKKPD-------VS-KSKE-----------C---- -S----DKNCPI------------------HGSLKLRGRTFTEKVVSAKAYRTATIEMER KNYIQKYERYEKRKTRLQVHNPECIN--AKEGDVVKVQECRPISKTKHFVIIKK------ ----------VK------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFTYMGKTLE--------------------ELSRMSINDFAELV PARQRRSLKRES------TDSQKTFMSKVMKGN-------------NIKTK-CREVI--- ------IIPQM----------------------------VGKNLRIHNG--------KEF V-----------ALLIQQEMIGHR----------------------------IGE----- ----------FVLTR-KRVSHHA------------------------------------- -------------PGVGA-TR-------------------------------SSASLSVR ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLASIDINKINDVCKYIKDIAEKTGVEMRGPIPLPTKKLKVT TRKSPDGEGK-------ASWERYEMRIHKRLIDL-AVDERALRLVMRVPIPEDLNIEIEM IDS----MARHSKAGKNYC---------------------------------------VI IMKK--DFSSE-----WIRSKQPRKQRKYRYN-APLHIKGKF-MAAHLSKELNKKY---- ---------------------NRR-SIKVRKGDKVTILRG--QFR--KKTGRIEKIDLKK TKTYIAGIEMIKKDGT-KVLYP----------IHPSNLVVTELNLD-------------- ---------DKK-RMAI------VNKLK-------------------KTDKIIKKQ---- ------------------------------------------------------------ --------EGKK------------------------------------------------ --------------------------------MARLRKFAAYRKI--------------- -E-RPYTRISKFR---KKSFIRSN-PNLKIVRFEMGDP----KKEFNY-TLELVSKTDL- -QIRHDSIESARQTSNRVL-EKELGKT-GYFMKIMIYPFHILRENPLAS-GAGADRMSTG MKKSFGKAIGAAAQVRK-GQKVCIVKV---N-KNGLETAKNALKRVSKKI--PNSYSI-- ---------------------V-----VKENKPVTISK---------------------- ------------------------------------------------------------ -------------------------------MLN-DPLANALSNILNKENARTKECLIKP SSKIIKEILNIMKDNYYIGKFKEIEDSK-GNILSVEL----------------------L NKINKCGVIKPRFSIKKDGYEKFEK--------------------RFLPAKGFGILIVST PQGIMTNEEAKKKSIGGKLLAYCY???????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????------------------------------------------------ ---------------------------MGKARNPRHGSMQFWHRKRAKRAYPKVKSY-A- N-SN-----EKNILGFAGYKAGMTHLLIKSARPNSMTQ--GESIFRPVTIIECPPLKVAA IKFYKRT--AYG-LK---TVNQILSKNFDKN-----L-----KKKM-------------- ----LIP---K--------K-ETN-----------------------QKEPE-------- -------SYDELRLLVYTQP-----SLTGIGKKKPELFETAIGGTK-E---EQIAYAKEN LGK-EIIATEILKPGQLIDTHAVTKGKGLQGVIKRFGVSLKSH--KSEKKKRA--TGNL- GPW--NQSSM-WRVAQPGQMGYHTRTDYNKLIIKVSD---KPD--DINPKSGIKHYGIVK NSYVLIKGSIQGSSKRLIRLNYAIR---P-H-KRKH-SETF-EIEHINIQK--------- ------------------------------------------------------------ ------MSKYKYS---------------------------------------ATVNEHRA R----------------------------------------------------------- -----------AVGLLMP-ISIKQSIEICNLI--RGKNLQKAKKILNEAKDMKKPIPFTR FTE-GAGHKH-----G-----IGP-GKYPVKACSEILKLISLVESNAQHKGL-DTSSLEI IHICANQGPKSWHY------------GR--QSRIKMKR-NHIEVVV-------EEKEIKK ---------KVVKKEPAKKEES-----------------KPVKKQEEKTGRKKEEKPKAI KQI-----EKVEKKQDIKTKPAEEKP--------SEAKT--------------------- ---------KNKVEEKK--------------DKPKKEQPKENVPAAELAEKAK-PKKVPA I-------------NKPIKKKESEV-----------------------------DKK--- ---------------------MGKRLIQQA-------------RGRGGPTYRAPSFRYK- GKASY-----FISSKG-KLNAK----IIDIIRCAGHSAPLVVLESNDNIR-NLMIAPEGI KVGDVVEYGE-------------KIA---AENGNMLLLKDVPEGTLVYNIEGQPGDGGKF VRASGAFARVISK-MK--S-KVVVQLPSKKEKEFHPNCRATIGIIAGGGRKEKPFLKAGK KFYAMKAKNKLWPSISGTSQNSVDHPFG-GSSSNHK---G-K----PTIAPKNAPPGRNV GALHPRRTG-------RKKK---------------------------------------- --------M-------------------VLTMN----------------------PSRNI KINKVTLNIGAGKDQVKLDKGIKLLKSI-TNV-SPVKTVTS--K--RIPGWGLRPGLPIG CKVTLRRK-SA-VDVLKRLIQAKDNNLRESQFDNNGNIAFGIEEYIDIPEVKYDPEIGII GLEVCVTLERN-GFRIKRRRIAKKKIPKSHIITKQEAIDFMKKKFNIEL-EGD------- --- >GCA_016871995 ------M-ATRN--RKVRR-LRGSR--TMGWGQIGQHR-KSGGKGGVGK-AGLLKHKWTW TVV-----YDPN--------------------------H-F--T-------RE-KPKPPQ RIIV------SKW----V-NVGQLDS----IAHSV--------QS---------DGGKKV ID--LSGMG--YQKLL----GQGSISGQY-KILV---DSASETAKEKIEKAGG--ELV-- LGTGSE------------------------------------------------------ ---------------------------------------------------------MSA V--------------------KNILKNYSRNIEL----------------DEYLAKQL-A ESGFGGVDIV------RSQVGTRINVYVMKPGLVIGRRGTGIKQLTEDLEKKFGLPNPQV SVA-EVSVPELNPYIM----------ASRIAQSVGR--GTAFRRAALFTLNSIMGAGAMG CEIGIAGK-L------------RS-------------ERAHFEKYK-------------- ----AGVVPKSGNTAKAIVRDATTDILMKMGLYG-------------------------- ----------IKVRIA---------------VKDA-----------IPKEF--------- ------------------------E-L-------------IEKRETRP-A---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------IEEKGK------------------------------------- ----VDDS-NESE----------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MKVAVYDLDGKEAE KAELPEIFSY-DYRPDIIRKAFYALRSHSMQRQGRDPMAGMRTSALSWN----------- -TGRGVARMAR-VKG-EGNSRAGQAAGVASVVYGRQAHHPV-----SERVVYQNLNRKER RLALVSAIAATSKSEVVLARGHKVS--KK-VTLPLIVSDDIQSVSKARNLKIAL---VKL NLEEELARIAN--RKALSGTARLRGRTKKQPVGPLIV-V-A-DDKG-------------- -----ISNAAEGLPGIKAVLARNLSTLDLAPGASAGRLTIWSRSA---LSALPKTIYQRV RVVAT------------------------------------------------------- ---------------------------------------------------------MLK RKRQGKTDYNTRKKII-RSKRNFAAIRITNKNTNVQILEAKIGGDVIAAAAHSREL-MKL GW----KGSGKSIPAAYLTGLLAGQKAKKA-GIESAIVYSGIKPFRAASRVAAAVKGIVD SGITVPV--NEEVLPS------EERIKGEHITAYASAGKGSES----PQFSTWKK--AQL STEKFGDHFGQIESKIKGGK---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------MSA-KSR-AVSAKG---VTEY-KPYITRSIPVYSVITCADNTGA KTLRVVQVQK--FKGRLKRIPAACVGDLITVVVKKGPPELQKQ---TFSAVVIRQKYPVR RLSGTRVVFEDNAAVLMTPE--GELKGTDIKGPVASEAAE-RWARVANVATMIV?????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MG--------------------QLQAMSMESLLALL PSRQRRSFNRGI------SEEKRELLEEIRRARD----SKKEA--I-IKTH-VRDMV--- ------ILPSM----------------------------LGMKIHVYTG--------KEF A-----------AVDIKPEMVGHF----------------------------LGE----- ----------FAITN-KKVVHGT------------------------------------- -------------PGIGA-SR-------------------------------SSLYVPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------AQFARIKLTSSNLENLEQVCKEIKGITEKTGVKVKGPQPLPTKKLKIT TRKAPSGQGT-------HTYDHWEMRVHKRLIDL-DADDRTMRQLMKIRVPEDVFIEVNL RAR--------------------------------------------------------- -----------------MATKRTKAR-KKYFS-APLHVYSKR-VSAVLSDDLKEKY---- ---------------------GKR-SARVRKDDNVRIVRG--EFK--GIEGKVTKVYSAE GRISIVGVNRDKLKGG-QIPIK----------IHASKVIMTGLNLS-------------- ---------DKF-RK-----------------------------------SSIEGDKL-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MKGKNYRIP--------------- -SGMPLTK---------KKYAPGA-PNPKIARFSTGAA----NPNYDL-ILQLASTEKA- -QIRHNALEAARVAANKKL-TP-IGET-AYYLLVKVYPHVILRENRMIA-TAGADRLQEG MRKAFGKPSGLAARVNH-GSVILELKI---M-SANKNAALDAMRSAATKL--PVPTKL-- ---------------------VE---FQTPIAKTQ------------------------- ------------------------------------------------------------ -----------------------------M-VAN-DILANLFSTMYNNEMRNKKECLIVP SSNLAVKVLKTMQSSKYIGEFETIDDGV-SGKIRIQL----------------------L GRINRCGVISPRFAVRGKEFGRWER--------------------QYLPAVGMGVLIVST SQGIMSHKEAQEKQVGGRLIGYVY---------------------------------MST KQSKEL------------SMEIEIPSNVTASLKQG-----IFEIK--GPLGTAKKDFN-L V-R----ATITV-EGKR-VKVK---PF-GRK---KKDKAVLGTASSIIKNLIRGVTKG-F TYKVKIVFAHFPITVKVK---GKE--IH-VENFYGERSPRVAQIV--GDCKASVQGD--- ----DVIIQGINIEDVGHTVANIEQATKVRR---KDQRI----------FLDGLYLYEKV KN---------------------------------------------------------- ------------------MG-------HRKHSSPRRGSLAFIPRARRQKLIPRVRTW-P- T-ISSD---KPTILGIPTFKAGSIHVMTSDDREKTPNF--GKPLFNASTVLATVPITIIG FRAYLKG--YDG-LQ---PFTDVFAENLPKE-----L-----ERKF-------------K M---------NTK------GSEEK-----------------------IKPITDN------ ---LS--NIKQVSALVSVTP-----EDALLSQKKPFIFEVIIGGGDIK---SQVEYAKSM LGK-SIKASDVFKAGMMVDVIGVTKGKGFEGPVTRMGIKRKQH--KSRKSVRA--VGVL- NPWH-PSTIM-YTVPRAGQMGFHQRMDRNKRILAIAN--AKDQ--PITPAGGFLHYGNVQ NDYLIVKGSVPGPIKRLVTLKLPSR-----H-VKVK-AEPP-KILQISTVPKR------- ------------------------------------------------------------ ----MPQFKYSFA---------------------------------------GYDPLVHV R----------------------------------------------------------- -----------SSGREVD-CSPKAAREVCEAI--KGKTLPRARSFLEDVASMKIPVAFRR YKL-KVGHKS-----QLQ--GFPS-GRFPQKTAKEILAVLDNLEANAEFKGF-DTEKIKI IHAVAHRGRKTLGYTP-------RAHGR--SSPSLNTL-THVELVA-------GEA---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRILVRR-------------RGKGGTQWRAPSKGKI- APAKY-----PLFNPEELVTGK----IVDIVHERGRSAPLSKILFKG-SI-NYVPAVAGL TVDSDIYMGA-------------SAP---LQQGSVLPLASIPEGSEICNIERRFGDGGKL VRVSGTSAILFSK-TG--D-NSIIRFPSGKSFIISSKCRASLGKIAGGGKTEKPFLRAGP RYYAKIAKNQQYPRVRGIAMAVVYHPFG-GGRHQHP---G-K----STSTSRNAPPGRKV GLIAPKKTG---------RKRITRGPIEVSS----------------------------- --------MKTVQIQ---------------SET----------------------PMKAI RVEKVVLNIGVGKAGEPHEKARKVLQEL-TEQ-KPAARAAR--D--SIRDFGIHKGEPIG AIVTLRKS-KA-IDVLKRILAARDNKVSTKSFDDNGNFSFGVKEHIEVPGIRYNPDIGIF GFDVSVVLSRP-GKRVSSRKRGRSKIGLSHRITKEEAVAFAREQLGMEV-VE-------- --- >GCA_002725495 -----MV-FKSR--SKVQK-QRGKR--THGWGHGKKHR-GAGNRGGRGK-AGLGKRGAQR KTLPLSQGKKPVGRIAN-------------------------------------NNSGMK KIRNS-RN--NT----II-NLENIVK----NLPNWIK-NKKV-KK---------DGSKYT LD--LGELG--YNKLL----SKGEISEKM-EIKV---SKYSASAKNKVEKAGG--KIL-- E----------------------------------------------------------- ----------------------------------------------------------MK E--------------------KEFIKQNLLHMKI----------------KESLEQKXGK AAEIGSISLE------KTPLGEKIIISTTRPGMIIGRGGEMIKELTRELKQKFKLDNPHI ETA-EISNPHTSAQVV----------ATKFAKELERFGPSRFKGIGYRELTRIMAAGALG VEIVVDGP-I------------PG-------------ARSKKWRFY-------------- ----DGYMKKCGFISDNLLDRAHCDAVLKKGTVG-------------------------- ----------ITVTIM---------------HPDT----------PLPDKI--------- ------------------------D-I------------V-EATKSE--PE--------- ------------------------------------------------------------ --------MVEEVS-----------EEKPK------------------------------ ---------------------------EEKKE---------------------------- ------------------------------------------------------------ ------------SKPKEEKKESKP------------------------------------ -----KEEKKESKPXE-------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MKTNIMXVXXGKSX EITLXXQFMX-PXRSDLVXRAVSSLQMXRRQPYGXDXMAGKRQGYTTVKXRX-K---FKT TYGKGVSRIRRKHLWXRGXQFXWIGAFVAXAXGXRKAFPPK-----SDXNLIERINXKER RXXIRSAISGSKY---------------------MILXDSFEKLKKSKDIINSL---IKX DLKSELDRLXN--KKIRSGKGKTRGRXYIXKKGXXVI-V-G-XMCX-------------- -----AVLATENLQGFDVXVVXNLNAELXAXXGNXXRRTIWTKXA---VEKLEKERXFL- ------------------------------------------------------------ ---------------------------------------------MAKGKR---YSVKFR RRREGKTNYKKRLAFV-KSDLPRLVVRRSNKYFNLQIIDNKPNGDVTLAHFNSKNL-SKL GW----KHSSKNTPAAYLSGYKLAEIALKN-KVKEAIFDMGSYTPTKGCTIYGALSGAIA GGLKISH--SKEVFPS------KDRIEGKHIS---------------------------- --DKLSVDLNKL----------------IGGKSNE------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAI-KINPVRSIPLGAEIIVADNSGA RSLKVISVKG--YKSRTRKLAAAXVGDLVTGSVIKGDVDNRHK---VVQAVVIRQKKEYA RPDGIRVSFEXNAXVILKDVKLGTPKGTVVKGPVAKEVAL-RWSQVGKLASILL------ ----------------------------MG---ESKIIM--------------------- --------------------------------EYSKRGRSFVGKVISXKMSKTVKVEWPR RKFLYKYERYQKKKSAVMAHVPEGMN--INLGDTVRISECRPISKTKNFVVVGK------ --------------------------------------------------------XKNE SN---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MKDKVFKFRGKTME--------------------ELTKMTNEEFALLL NSRKRRSLLRLN------RHDSKKILEKVDSGKSK------------LRTH-SRTTV--- ------ITPKL----------------------------VGKTIEVYNG--------QKF I-----------XVKITEEMLGYY----------------------------LGE----- ----------FSQTR-RIASHKG------------------------------------- -------------IGVGA-TK-------------------------------SSKNQGKK ------------------------------------------------------------ ------------------------------------------------------------ ------------MPTARIKLYGTNLEKLNTVIDQIKNISKTTKTKLAGPISLPTKNLVVP VRKSPQGEGK-------ASWERYEMRIHKRLIDL-NADERALHLLLRVPIPHDINLEIQL IE---------------------------------------------------------- -MKT--KFANV-----WKRSVQPRKQRKYRAN-LPNHLKQKL-MRAPLSKELRKKY---- ---------------------NKR-SLTLRVGDTIKVVTG--QFK--GVMGKIDIIDYNK NKIKLTGAELVKSNGQ-LVKYP----------IDPSNVTIITPDLS-------------- ---------DKK-RK-----------------------------------EILERK---- ------------------------------------------------------------ ------------------------------------------------------------ ----------------???????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????----------------- -----------------------------M-ANN-DLMANALSKLKNASERGKKEVDIYP SSKTITKILDLLQKDGYIESYENNETNK-GVFTKVKL----------------------S GKINNIGVIKPRFSVKLDTYEKFEK--------------------RYLPAKDFGRIFVST TAGIINHLEAKQQNKGGVLLAYVY-----------MSTTRRTRVRGTGFRKMGKFRPVLR YRAKKFIKPMPIPEKXIPIKNLELPEGFSMKVEKN-----NFTIS--HSSGSLSREYP-S S-S----LELNL-NXNN-LEIK---GK-SHN---KRVKALVGTFMAHIKNMIKGIEKP-F VYKLSIKSVHFPMTANYS---GSK--FE-LKNFLGGKFNRSTEIP--SNVELKLNGS--- ----DIELISSDIESVGMTATRLEQLTRVNK---RDRRV----------FQDGIFITHKG DKKL-------------------------------------------------------- ------------------MGS-----TAGFRRRPRRGSLQFWHRKKANRMVPRXRSW--- XXLN-----ENXLXGFXGYXAGMTQISFIDNRESSPTX--GEEIMMPXTVIEXPQIIPFS LRLXSKT--PYX-XK---VRXELYAXNLDLS-----L-----SKRX-------------- ----TLP---K--------KXSSKT----------------------XEDMKXD------ ---LE--NVXXIRMLVXTKP-----SMTGSXKKKPDXLEIPVXGSXXE---XXFXXASXX XGK-EVNISDXFSDGDXMDVVGVTXGXGXQGXVXRXXVSILHR--KSHGXGRRK-VASL- GXWQAKT----WRVPHXGQMGFXXRXVMNIQLMKILD---SXE-XXVTXKGDFVGXGKVS GKYILVAGSVPGPKRRLIRLNFXKR-----R-KASAXKEVX-EVT-ISMESQQ------- ------------------------------------------------------------ -------MAISMQ---------------------------------------NYDSKNMS K----------------------------------------------------------- -----------AVGLNLP-FSFKVAYEVAKFL--RGKKVKRAIREMEEVSLLKTAIPYTR YNK-DTPHRR-----X----KMAA-GRYPVKAAKYVLPLLKSLESNAKDKGL--TGELKI IHSAAQKPSIRRRY------------GR--VRGTKR-V-THFELV--------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------AQP--------EDKK------- ------------------------------------------------------------ ---------------------MGKRLIQQR-------------RGRGGPTYRAXTXRXI- GKTYYP---FFXGEXQ---TGQ----IAXLVNSTFNSAPLMXXEYXDXQL-XLLPAXEGX RVXQSIEXX--------------XNN---XXXGNILQLDNIPSGTLIYNLEKTPGDGGKF VKTSGTYAQVIGK-EG--K-GVAVKLPSKKKVILNSNCFATIGIAAGAGRTNKPFVKAGN KFHAMKARGIRYPIVRGKAMNARDHPHG-GTHNRNSRGGGKY----STTRPRNLPAGKKV GSIAAKRTG-------KRK----------------------------------------- ------------------------------MVN----------------------KMKQI QVEKITLNIGSGPDPREVERGMKLLEKI-SGM-KPVEAKVR--AGLRIAAWKIRPXLAIG SKVTIR-K-NT-EELLLRLLKAVDMKIPESKFTENG-FSFGIHEYIEIXXVKYDPKLGIF GLNISVTLKRP-GFRVKNRKLVNRKIGKTHRLNKEDAIEFVKNKFGVIT-E--------- --- >GCA_007117755 ------M-TIAR--KKNSR-MRGSK--THGGGSMKKRR-GAGHRGGRGK-AGSGKRGDAK K---------PVYWKD---------------TK-----Y-F--R-------KK-KFTVP- -NKK--ET--LS-----I-TLKSLDT----NLNDWVK-NKKA-SL---------KEGSYE VN--LQNLG--YNKLI----GTGEVKNKI-VVHV---NKATLKAKEGVESLGG--KIV-- L--------------------------LLDKKDADKKES--------------------- ----------------------------------------------------------MA NK--------EFNPHDNISVVNIVVSTSLEHDIP----------------LEKMTANL-S NTEYNPEQFPGLVIRIKEPKTSALIFSS---GNIVCTGAKSLDKVQESID---------- ----------------------------KIIESLEKI-GIKIKIKPKINVQNIVASGSIG MDLNLNTLAMQLDNTEYEPEQFPGLVYKLME------AKATFLLFS-------------- ----NGKIVCTGTKSEEMVHKAV------------------------------------- ------------------------------------------------DML--------- --------------------------M--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --ETLKRYKK-------------------------------------------------- ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????------MKAN---YTIPYK RKKQGRTNYKKRLALL-KSRETRLVIRKTNTQIIIQFTNYKPDGDEVIVSYNSSKL-KED GW----KDSYKNLPSAYLAGYKAGLLAQKK-GVKKAVLDTGLQIHKKGNRIYSAVKGIVD SGLKIPV--DEKVYPK------EERVKGEHI----------------------------- -SKEYPVLFEKTMKKI------------SKG----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????MGEDILKRNK------PTEKELEKIKEQDKHIDSELEKKEDAKGEEGISTHIF AIRV--TANREDQVMSFLISNIQRKKMNVYSVIRPHGLRGYIFAEADVRQDVEEAAFGVP YSRGLLPGEVPYKEIEHMLEQAKK-DVNIKKNDIAEIISG--PFK--RQQCKIARVDKAK EEVVVELLEA-------AIPIP--------ITLKMDAVKVVRREE--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MAKLMRAVAWRRL--------------- -E-RPYTRKSKYR---SKDFIRGV-PNSKVVKYVMGNK----DKKFEY-KLLLVSERDI- -QLRHNSLEAARKTTLKHL-DRK-APL-NYFFQLRVYPHHVLRNNPLAA-GAGADRMSTG MSHSFGKPVGIAARVKK-GQEVFEVRV---N-KERLEAAKISLKRARMKF--PCDFKI-- ---------------------V-----VQKA----------------------------- -------------------------------------------????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????????????????------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -YKLKICSGHFPMNVSLK---GDV--LE-IKNFIGESVPRKLKIK--EGAEVKINGD--- ----EITVTSSNKELAGSTTGLIEKLTRRRG---FDKRI----------FQDGIYITHKP KREL--------???????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??? >GCA_002686215 -----------MYGTSNVN-LRILI-------------------------ASLKKKS--- -----------NFWKK------------------------V----------SE-LLSVPA RKRI------------TV-NLGKLNDY-----------------K---------DGDIVV IP----------GKLV----AGGQLDKKL-TISC---WRFSEAVLTKIKNSGS--KVV-S LHDLAMK------------------------DSNGNTLRLVA------------------ ----------------------------------------------------------MK E--------------------KEFIKQNLLHMKI----------------KESLEQKTGK AAEIGSISLE------KTPLGEKIIISTTRPGMIIGRGGEMIKXLTXELKQKFKXXNXHI ETA-EISNPHTSAQVV----------ATKFAKELERFGPSRFKGIGYRELTRIMAAGALG VEIVVDGP-I------------XG-------------ARSKKWRFX-------------- ----DGYMKKCGFISDNLLDRAHCDAVLKKGTVG-------------------------- ----------ITVTIM---------------HPDT----------PLPDKI--------- ------------------------D-I------------V-EATKSE--PE--------- ------------------------------------------------------------ --------MVEEVS-----------EEKPK------------------------------ ---------------------------EEKKE---------------------------- ------------------------------------------------------------ ------------SKPKEEKKESKP------------------------------------ -----KEEKKE------------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MKTNIMRVSGGKSA EITLPQQFME-PVRSDLVKRAVSSLQMSRRQPYGADPMAGKRQGYTTVKRRK-K---FKT TYGKGVSRIRRKHLWSRGSQFYWIGAFVANAVGGRKAFPPK-----SDKNLIERINKKER RKAIRSAISGSKY---------------------MILDDSFEKLKKSKDIINSL---IKN DLKSELDRLEN--KKIRSGKGKTRGRKYITKKGPLVI-V-G-DMCP-------------- -----AVLATENLQGFDVSVVNNLNAELLAPGGNIGRRTIWTKSA---VEKLEKERLFL- ------------------------------------------------------------ -----------------------------------------??????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MKDKVFKFRGKTME--------------------ELTKMTNEEFALLL XSRKRRSLLRLN------RHDSKKILEKVDSGKSK------------LRTH-SRTTV--- ------ITPKL----------------------------VGKTIEVYNG--------QKF I-----------PVKITEEMLGYY----------------------------LGE----- ----------FSQTR-RIASHKG------------------------------------- -------------IGVGA-TK-------------------------------SSKNQGKK ------------------------------------------------------------ ------------------------------------------------------------ ------------MPTARIKLYGTNLEKLNTVIDQIKNISKTTKTKLAGPISLPTKNLVVP VRKSPQGEGK-------ASWERYEMRIHKRLIDL-NADERALHLLLRVPIPHDINLEIQL IE------------------------------------------------------MGIY TVRT--AIGREQQVMDALSTNAKRAD-GVHALLSPYGVVGYIFIEADSLTDVQQISYRVP YVRGVLTREXELXSIEHLIEFKXE-NVDIQLGDIVEIIGG--PFK--GERGKVTRLNTQK SEVIVELLEA-------AVPIP--------ITLNLDSVRVVGIEGR-------------- ---------EE------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------???????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????------------------------------------------------ ------------------MGS-----TAGFRRRPRRGSLQFWHRKKANRMVPRVRSW--- KILN-----ENKLSGFAGXKAGMTQISFIDNRESSPTK--GEEIMMPVTVIETPQIIPFS LRLYSKT--PYG-SK---VRSELYADNLDLS-----L-----SKRL-------------- ----TLP---K--------KRSSKT----------------------LEDMKKD------ ---LE--NVSEIRMLVHTKP-----SMTGSEKKKPDVLEIPVSGSSVE---EIFNYASTI LGK-EVNISDVFSDGDLMDVVGVTTGKGFQGSVKRFGVSILHR--KSHGDGRRK-VASL- GNWQAKT----WRVPHPGQMGFHNRTVMNIQLMKILD---SAE-VPVTPKGDFVGYGKVS GKYILVAGSVPGPKRRLIRLNFAKR-----R-RASAFKEVP-EVT-ISMESQQ------- ------------------------------------------------------------ -------MAISMQ---------------------------------------XYDSKNMS K----------------------------------------------------------- -----------AVGLNLP-FSFKVAYEVAKFL--RGKKVKRAIREMEEVSILKTAIPYTR XNK-DTPHRR-----X----KMAA-GRYPVXAAKYVLPLLKSLESNAXDKGL--TGELKI IXSAAQKPSIRRRY------------GR--VRGTKR-V-THFELV--------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------AQP--------EDKK------- ------------------------------------------------------------ ---------------------MGKRLIQQR-------------RGRGGPTYRAPTHRXX- GKTYYP---FFXGEXQ---TXQ----IADXVNSTFNSAPLMVIEYXXGQL-XLLPAPXGX RVGQSIEYX--------------XNN---VTKXNILQLDNIXSGTLIYNLEKTPGDGGKF VKTSGTYAQVIGK-EG--K-GXAVKLPSKKKVILNSNCFATIGIAAGAXRTNKXFVKXGN KFHAMKARGIRYPIVRGKAMNARDHPHG-GTHNRNSRGGGKY----STTRPRNLXAGKKV GSIAAKRXG-------KRK------------------------------??????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??? >GCA_011056255 ---MMSI-PRRR--KKSRK-MRGSR--FHGYGLQRQHR-RSGRRGGFGM-AGTKKHLWTW VTA-----YEPD--------------------------Y-FGRG-------RR-GFKRPR AVRK--EI--RS-----I-NLADLDK----MIPELLR-SGIAEER---------EDGRIE LD--LGKIG--YNKLL----GRGEISKPL-LIKV---ESASRNAVSKLESIGG--SVI-- LTEG-----------------------------DSDEPG--------------------- -------------------------MSS--------------------------AKSMPI Y--------------------KKFVQEGIVKYKL----------------HEFMEKIS-D KAGFHGVEIS------STPIRDIITVYVESPGVMIGRGGRTSKRISDILREELGIQNPYI QAK-KVDKPFLSTRIV----------ASYIARRIAK--GERYKKVAYSALGRVMAEGAKG VEIRLSGK-F------------GS-------------QRAREERFR-------------- ----EGVIYRCGQDYIENVEYAVKHVLMPQGMIG-------------------------- ----------VRVRIV---------------KPGV----------RGPDAV--------- -------------VIK-ED-----E-I----------ERIRERIKSE--IE--------- ------------------------------------------------------------ ------SLSESEVVEI--------PEELEGEL---------------------------- ---------------------------EVASE---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----VKEDESEQA----------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MEVPVYNLNGEIIG RIELPTLFEL-DVRQDIIRRVYLSQLTARIQPQGRDPLAGLRTSAESLGVGH-------- ----GIARVPR-VKG-RGYPAAGRAARAVMAVGGAKTKAPR-----SWKVVWERVNKKER RLAIGSAIAATSHPELVRMR-HRIP--EG-IALPIVISDDIESIAKTSDLHKLL---KKL GLEEELERCKRRFRKIRAGRGKMRGRVRQRARGPLII-Y-SREDSP-------------- -----LKLASRNIPGVDAVSVRNLSVIHLAPGGKPGRLTIWSESS---IKALEEVRIIA- ------------------------------------------------------------ ---------------------------------------------MARSGR---YKVKFR RRREGKTDYMKRLALL-KSRKPRVVVRRTNRYIIVQFVEFKGEGDEVIAYAFSKEL-EKY GW----PYGGKNLPAAYLTGYLAAMRAKKA-GVMEAILDIGRFPSTRGSRLYAALKGVLD AGIDVPH--SPEILPD------EDRIRGEHIVSFAEKLEEEG--SLERQFSDYLR--KGA DPKIIPETFESVLEKI------------SAISND-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------MSKVARRR---------KVEGV-KPKITRGLPVRARLKCADNTGA KLLMIIGVHG--YKGRKDRVPTASVGDMVTVVVKRGKYDLMHK---PFKAIVVRQRMPYR RKSGQWVVFEDNAAVLVNDD--GTPRGSEFRGPIAKEAIE-RWPSLSVISAQVV------ -------------------------MRKISEDLLEDIAP-PERS-----------C---- -D----DDKCPW------------------HGNISLRRSSLDGRVISTKMTGTVTVLVEY LHYDKKYKRYERRRSKIHAHLPPCIE--VNEGDLVRIVETRRLAKTVSHVVLGK------ ----------LK------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSSREFRYRGYTLE--------------------QLQNMTLDELANVM PSRIRRTLRRGL------SIENKKLLDKVRKYKA----MGIDK--V-IRTH-RRDMP--- ------ILPEM----------------------------VGSKIAVHNG--------KEF V-----------EITIVPEMIGHY----------------------------LGE----- ----------FAMTN-KIVRHGK------------------------------------- -------------PGKGA-TR-------------------------------SSKFVPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------TEILRIELVSVNPESLERVSKMFKEIADKMGVRVKGPIPLPTKRLRVT ALRNPSGEGT-------NRYDKYELRIHKRIIDIPNPDERYIRSIMGVTLPDDVKISIVL M----------------------------------------------------------- -MRT--------------KSHKPSKQRKYLYN-APIHHRGKI-MSAPLSEELKSKY---- ---------------------GIN-SIPIRKGDRVKVVRG--DYR--GTEGEVVSVDRKR YRIAVKGIVRRKADGT-EVPVP----------IHPSKVVITKLYLK-------------- ---------DEA-RK-----------------------------------RLLERKGV-- -----KAEEIVEESE--------------------------------------------- ------------------------------------------------------------ --------------------------------MS-LRPARNYRAL--------------- -Q-RPYTR---------KEYIKSI-PYSKITKFDHGNV----HGKFEY-EVRMVAEASF- -QVRSNALEAARMTVISQI-RKAVPSDEAYFFKIVHYPHHILRKHAMAG-VHKAERLQKG MRLAFGKPDARAAQIRR-GDVIMLLRV---N-GQHLEAAKYCMKLAKLKI--PYMTRID- ---------------------------VVRLNGTEGEDE-EGA----------------- ------------------------------------------------------------ -----------------------------M-TRL-DPLADAMSTLTNGSMLGKREVVINI ASKLIGKVLKVLKEHGYIDEFEYVDDGR-FGKYVVRL----------------------N GRINKAGVIKPRFPVKVSEFSRWEK--------------------IYLPAENVGLIIVST NQGVMTHREAKERGIGGVLIAYCY-------------------------------MRYPK VITLAL------------ESEVPIPEGVKVEVDGS-----KIRVS--GPKGTLEREFH-- ----NELIELSI-ENGK-VKVR---TY-GDR---KFNKAYLGTVTAHIRNMMKGVTEG-F KKEMVIVYAHFPIKVEVD--KGRK--IVKISNFLGEKLPRYASIV--GDTEVRVEGD--- ----RIYIEGISKEEVGQTAANIRLATKIKK---KDPRV----------FMDGIYVVS-- ------------------------------------------------------------ ---------------------------MPR----RHGSLQYYPRKRAATQKALFRSY-P- E-LSVD---KPTLVAFPGYKVGMVHVLLKEDRPGKLNL--GQQVTLASTVIETPPIEVVG FRAYKEG--YYG-LKP--LATALRIERKDPI-----------SRTL-------------- ----TIG---DGVD-----NFNEA-----------------------LSKLEGA------ -------EVSEIRILSYTRP-----DLAGIHKKKPEFMEIPVKGGEME---ERIEFAKSL VGS-QLKVDSVFKVGQLVDVTAVTKGHGWQGVVRRFGIELLRH--KAGKGRWR--VGSL- GSRH-PPYVT-WRVPRAGQTGYHKRTEYNKRILMMGDL-TKGD-LDLSPKGGFKNYGILR SQYILLSGSVPGPAKRFVFIRHPIR---P-NYAELP---AP-EIYYVSS----------- ---------------------------------------IGWLRG--------------- ----MPTWGYSYA----------------------------------------AQGEKEA M----------------------------------------------------------- -----------ASGRDLR-VSFKEMVELLREI--RGKKLSEAYNILDDVIALRRAIPFRR YNG-GVPHRK-----GIS----GA-GRYPVKAAKLLKKILKSAEHNAMNKDL-DPDNLYV KHAAAQMGMKLRRFFP-------RAYGR--ATPKIEQM-VHVEIVL-------EEREESE ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------E---------- ------------------------------------------------------------ ---------------------MGKRILVQR-------------RGRGGIQFRSKDHLKI- APARYP-----QDGMDNLLRGV----IKEILHEPGRHTPISLVELENGQE-FYYIPPEGV YEGQEIQIGK-------------GAE---IKTGNILPLSEIPDGSLVCNVEIRPGDGGKI ARRSGTYAIVFSH-EG--D-KVILRLPSRKEKLVDARCRATIGVVAGSGRIEKPFMKAGI KYYHERTHPKRWPVVRGVAMNPVSHPHG-GGSHKRP---G-K----PTTVARTAPPGQKV GHIAARKTG-------RAKRRAATKR---------------------------------- ----MEDLREEILR--------------RWESN----------------------PMLVP RVMAVTLNIAVGRSGEVLTRAGKVLEEL-TGQ-KPVERRAK--R--TIREFGIRKKEPIA VSVTVRGK-KA-VELLDRVAEAVGRRVKASSFDELGNFAFGIKEHIDIPGVKYKAEIGIF GMDVIVSIGRA-GYRIARRRIERRRVPLRHRVSKAESMLFAEKYLNLKV-VHEEE----- --- >GCA_002867475 -----MT-VNKR--KKNSR-QSGSK--THGWGSMKKHR-GAGNRGGRGR-AGSGAKGDAK K---------PSYRKEP-----------------------V--G-------KI-GFRSP- LINQ--KV--ST-----I-NLSLISQ----RLENMIE-KKQA-VK---------GKSGIE LD--LTKLK--IDKLL----GSGNVSEKL-IITV---GEASAKAIEKVEAAGG--KVT-- VLYGGD--------------------EFEDSNDDAEEEAEEKEE---------------- ----------------------------------------------------------MI E--------------------RKFISDKLKEFQV----------------QEYLTENL-K NVGHSNTKIQ------KSPLGDKVIITASRPGLIIGRQGANIKTLTKTLKNKFKLENPQI EIN-EVEKPNLDAQIV----------AEGIAGNLERYGSQRFKGIGHKVMTDVLRDGAIG VEILISGK-I------------PS-------------SRAKTWRFY-------------- ----AGYLKKCGNIALTDVKTSYASAQLKTGTVG-------------------------- ----------IIVKIM---------------PANI----------RLPYDI--------- ------------------------R-L------------IGEEAAEE--LE--ETSEVT- ---------------------------VEEP----------------------------- ------IVVEEETTT----------EEFEAEK---------------------------- ---------------------------EAVEK-----------------KAVTEEPKTEA TEEKAAP----------------------------------------------------- ------------KKKAVKKKAPAK------------------------------------ ---KAKTEEKAEE----------------------------------------------- ------------------------------------------VAEK-------------- ----------------------------------------------MKAKVFSITGQAGK DIEFPTQFNE-EFRPDLIKRAVLAIQAAKRQPYGADPEAGKKHVTKISRRRH-K---FKG SYGAGISRVPRKIMSARGTRFNWVGALAPGTTGGRRAHPPK-----AEKIWTQKINVKER RKAIRSALAASINANLVEDRGHKVP--K---TYPLVVETKAEEIAKTKDAIQML---IAL GLKDELTRCQV--KKVRAGKGTMRGRRYQRKKGPLVI-V-S-KDSN-------------- -----LHKALRNVTGVDIVVADNLNTELLAPGTAAGRISVYTEDA---VAKIGG--LFK- ------------------------------------------------------------ ---------------------------------------------MVHDKI---QKIPFR RKREQKTNYKKRLALL-KSGKERLVVRVFNKHILAQLIKY-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAS-KSNVTRALPVGAYMETCDNSGA KVVKITAVKR--HKTVKGRLPAAGVGDMVQVAVKKGKPDIRKT---VQFAVIVRQKKEYK RSDGTRIKFEDNSIVILKDEK-GNPKGTIFKGPIAKEATE-RWPAVAKVASIIV------ ------------------------MKKNIG---IE-VKQ-PENT-----------C---- -D----DINCPF------------------HSNISLRGKVFEGTIVSNVFHKTVSVEWER RLKIPKYERYEKRRTKIRVHSTPCIE--VKPGDKVKIMECRPISKTKNFIIVEK------ ----------I------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFIFNGKSIE--------------------ELKELSDKEFAELI PSRERRTILRGY------TEEQKRFIEKIDAGKN------------HIKTH-CRDIV--- ------ILPKM----------------------------VGKTIKIHTG--------REF I-----------DLLVQDEMIGHR----------------------------LGE----- ----------YALTR-KRVGHSA------------------------------------- -------------PGVGA-TK-------------------------------SSAHVSVR ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLASIDIHKINETCDFIKDIADKTGVEMRGPIPLPTKKMKLT TRKSPCGDGT-------ATWERYEMRVHKRLIDL-GIDDRALRMVMRVPIPEGLNIEIEM IEA--------------------------------------------------------- -MKQ--EFSKS-----WNNSKKPSKQRKFRAN-APLHTKSKF-LSTHLIKELREKH---- ---------------------GKR-SVRVKKGDKVKVLRG--THR--GKTGKVEKVSVKL TKVYVTGIDTIKKDGA-KALYP----------LNPTNLMITELDLS-------------- ---------DNK-RKE----------------------------------KMTKK----- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MARLRKAVAYRKL--------------- -E-RPYTRKSKYR---NRSYVRAV-PNNKIVKYVMGDT----KKEFPS-EIILTSGADI- -QVRHNSLESARLAANRYL-ERNLGKK-GFQLKLRVYPHHILRENPLAS-GAGADRMSTG MKKSFGKSIGLAAQVRK-GQTLLSVTV---E-KGQEKIAREALRRSLSKF--PMSGQI-- ---------------------L-------------------------------------- ------------------------------------------------------------ -----------------------------M-AMN-DPMANILSHIQNYEKIGRKEVLLNH SSNVIKEVLRVLNENSYIGDFEEIDNGK-GGLVKLNL----------------------L NNVNKCGVIKPNFQIKKVEFDKFEK--------------------RFLPAKGFGILIVST SQGIMTNEQAKEKGIGGKLLAYCY------------------------------------ MKVEKL------------EDKTSIPEGVNLSYEGG-----IVKVT--GPKGEVTKKMF-Y P-G----MKIEV-TDGE-VVIS---YE-KAT---KREKKMIFTYTAHIKNMFKGVTEG-H KYELKICSGHFPMNVAVS---GDT--LT-VKNFIGEKVPRTLKLK--NGVDVKVNGD--- ----IIIVENINKELAAQTAADIETITKRKG---FDTRI----------FQDGIYIISKD GKSMGN------------------------------------------------------ ---------------------------MAKVGRPRHGSMQFWPRKRAAKETPKLRSF-P- K-VD-----SALPVGLAGYKVGMTHLTFTDNRKNSKTK--GDLVTWPVTIVEVPNLKVIG ARFYKNH--YGG-MQ---PLTDVRADKLDKT-----F-----ERKL-------------- ----TAP---K--------KVNNK------------------------------------ --YPD--SFDEARVLLGTQP-----SLTGFGKKRPEVFEMAIGGSN-E---EKIAYIKEN LGK-DLSPSDILKEGELLDSHSVTKGKGYQGPVKRFGIGLKAS--KSEKGRRR--PGSL- GGWKGHAHFM-YRNPNAGKMGYHLRTEYNKLLLKIGD---NPE--EINAKGGFIRYGLVK NNYLLIKGSLGGPHKRLVILNKAIR---P-N-KKLAIGEVP-SIEHVSTSSKQGR----- ------------------------------------------------------------ -------MGYSKN---------------------------------------EYDEKSMA R----------------------------------------------------------- -----------ALGKDLS-ISTKVSIEMCKYL--RNKSTKRAKQILSRVLEKKEAIPFTR FNW-DMGHKP-----G----DMGP-GRYPQKASEELLALIKSVEANASSKGL-SVDNLVI SHLVAQKASRPWHY------------GR--QRRRQMKR-THIEIMV-------KEA---- -----------ETKAKPAKESV-------------------KSAPEPKKETPKP------ -------------KAESK------------------------------------------ --------------------------------PATKEET------------PK-AEKQAE ------------------VKEK-------------------------------------- ---------------------MGKNLIQQA-------------RGKGGPTYRSPSFRYK- GEAKF-----PSTEV----SGV----ITDIISCQGHSAPLFEVKYDDNTC-GYMIASEGK RVGDK------------------------ITGESVTALKNIPEGSFVYNIEARPKDGGKF VRAGGAFAKVVTK-TK--D-RIIVLLPSKKQKEFHPECRAAIGVVAGGGRTEKPFLKAGN KFFAMKAKNKLWPIVSGSAQNAVDHPFG-NKRSSRK---S-K----ARPAPNNAPPGRNV GMIRPKRTG-------RKK----------------------------------------- -------------------------------MN----------------------QMKEI RIDKVTLNFGAGKDHNLLNKGIKLLEIV-SGV-PPVQTTTD--K--RIPGWGLRPGLPIG CKVTLRGK-KA-EELLSRLIKAKDNIIPKSSFDNSGNISFGIHEYIDIPDAKYDPDIGII GLQVSVTLKRP-GFRIKNRSVKKSKIGKPHMITQDDAMNFLNEKFDVKQ--GE------- --- >GCA_002687795 -----MT-IIKR--KKNTR-QRGSK--THGWGSMKKHR-GAGSSGGRGK-AGSGKRGDAT K---------PRIWKD---------------KK-----Y-L--G-------RY-GFKTP- GSKT--KT--RT-----I-NLLDIEL----RFDNLLSMKKIA-EK---------EGI-FN IN--LKEMG--YDKLL----GKGKVTKKY-NINV---NSASAKAVDKVGKAGG--KVI-- I---------------------------PEQKKAVPEPKPEPKP---------EPKPEPK QSA-------------------------------------------------------MI E--------------------RKFVAQKTKEFLV----------------QEYIEENL-K RVGHSHTKIV------KTPLGVKVIIYASRPGLIVGKKGQNIKKLTNAIKKKFDLENPQI EIN-EVENIGLDAQII----------AEMIANSLERYGTSKFKGIGHKTMANVLEAGALG VEILISGK-I------------PS-------------SRAKRWRFY-------------- ----QGYLKKSGDISQEGIKKATTSAQLKSGTVG-------------------------- ----------IQVKIM---------------PPDI----------QLPDEV--------- ------------------------K-L------------K-EEITEE------------- ------------------------------------------------------------ ----------EEGS-----------EEEKEKK---------------------------- ---------------------------EDAKE-----------------SGEEKPEKETK KE---------------------------------------------------------- ------------TKEKTEKKAKSKET---------------------------------- -----KKETKQDKKNG-------------------------------------------- ------------------------------------------NAKK-------------- ----------------------------------------------MELSILSSTKTEIG KIKLPTQFEE-EIRPDLIKRAVLSIQSHKRQPYGADKLAGKRASATISKRRR-N---YRG CYGIGISRTPRKIMSRRGTRMNWVGAFVSGTVGGMKAHPPK-----AEKKWEQKLNKKER RKAIRSAIAATLNKQYVKNRGHILP--D---DYPFILESKIESTNKTNQAKELL---EKL GFKEELERTGK--KKIRAGKGKLRGRKYKTKRGPLLV-V-S-EDCR-------------- -----LSKAAANIPSVEVCNVKNLNAETLAPGAVPGRLTIFTDKS---IQILEKERLFSQ ------------------------------------------------------------ ---------------------------------------------MKKT-----YNVKYR RKRQGKTDYNNRLRLL-SSHKLRLVVRASLKNISLQVVKYNSEGDMVLLSVSSKQLQKQF GW----NKSKGNRAAAYLTGSLLGKKAKEK-SLTDMILDMGNYPNVKNSRVYAALKGVVD AGISIPH--SKEIFPS------EELIKGN------------------------CK--DEF D--NTKKRIIEVKQNG------------KE------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKSL-SFRITKALPMGTVIKTCDNSGA RLIRIFSVVG--AKTVKGRIPAAGVSDLVFASVKRGSPEMKKQ---KVYAVIVRQRKEYK RPDGTRLKFEDNSAVVLKDEKSGSPKGTIIKGPVAKEVCD-RWPGIAKIANIVV---MTK --------------------------KKTT---LK-IKA-PDKD-----------C---- -K----DSKCPF------------------HGSLKTRGRVFVGVVTSKDTHRTATVVFER KVYVPKYERYLKKRSKIHVHNPSCID--AKPGDFVKIVECRPLSKTKKFVAIEM------ ----------LG-KDILF---KQKEEALESAKIKEKKEED-----TQKEKETESKEGKKL SNEGEKGLEKAKTFQK----EKPEEKKEQETQKENKE----------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------MKKEFTYRGKTLS--------------------EINQLGTKELASLL PARQRRSLLRGF------TEPQKRLLAKIKKQKEG-----KYQ--KTIKTH-CREMI--- ------ILPDM----------------------------IGMNILVYSG--------KVF N-----------PVNIQENMIGHL----------------------------LGE----- ----------FVLTR-KKGEHSA------------------------------------- -------------PGVGA-TR-------------------------------SSASVSVK ------------------------------------------------------------ ----------------------------------------------------???????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- -MKN--KWSAN-----WKSSKQPRKQRKYRIN-APLHIKQKF-VNAHLSKELKKKH---- ---------------------SRR-ALALRKGDKIKIARG--QFK--GKTGKVDKINLSN YRVYVTDIMVAKKDGT-KAFFP----------LHPSNLIITELILE-------------- ---------DKK-RQ-----------------------------------KILDRK---- ------------------------------------------------------------ --------NK-------------------------------------------------- --------------------------------MARLKRFCSYKIL--------------- -E-RPYTRISKYK---KKSFIKAN-PNKVIVRYDMGTV----KKSFSC-TLNLVSKEDL- -QIRHNAIESARQTSNRLL-ENELGRK-GYHFKVKIYPFHILRENPLAS-GAGADRFSTG MKHSFGKPISSAARVKK-GQTMFTIST---N-KQSLGTARKAMDKARHKL--PCSCTI-- ---------------------Q-----VIEKKAT-------------------------- ------------------------------------------------------------ -----------------------------M-SMN-DPLANVLSKIMNAENRERSECIIKP VSKLIKKVLEILSDEGYIGEVKEIEDNK-GNMLQVAL----------------------L GKINKLNVIKPRFFVKKDGYEKFEK--------------------RYLPSNDFGVLIVST PSGLKTNKEAEKKETGGRLIAYVY------------------------------------ MRPENI------------EEKIEIPKGINAALDRN-----TLILK--ADKGELKRKLL-S K-T----VNFSI-ESNA-VKLA---AN-KPS---KREKKIIGTFKVHIKNMIKGLTEG-H VYKLKVCSSHFPMTVSVS---NNE--FI-IKNFFGETSPRKLKIT--EGVEVKVEGE--- ----IITVNSINKEHAAQTAGSIENLTRRVN---FDRRV----------YMDGIYITEKD GKEIKL------------------------------------------------------ ---------------------------MPTTRSPRKGSLQFWPRKKAKRQYARVRCW-A- K-LD-----EKSVLGFAGYKAGMTHIGFIDNRPNSLTK--GEEVSCPVTIVECPPQKTAS IRFYKQT--PYG-SK---LCSEIFAEKLDKE-----L-----KKKL-------------- ----IMP---K--------K-K-G-----------------------SEEVK-------- -------DYDDIRLLVYTQP-----KLTGIGKKKPEVFEMGLSGSK-E---DKLALAKEL LGK-EIDIASVFKESQLVDIHAVTKGKGFQGPVRRCGVSIRGR--KSEKTKRG--PANL- GPW--TGART-WRVAQAGQTGYHTRTEYNKLLLKIST---KPE--EINPKGGFPHYGLVK NTYILLKGSLPGPAKRLIRFNHPIR---A-N-KKLV-SEKL-DIKHISMESKQ------- ------------------------------------------------------------ ------MQKYSFN----------------------------------------YNKESMA K----------------------------------------------------------- -----------ALGSSLP-ISTKHSAEICKLI--RGMSLTKAKELLVKAISKQKAIPFNR FNM-DLGHRA-----G-----MGP-GRYPVKASKEILNILESVESNALSNDM-NKEKLII AHINAQKASSPWHF------------GR--QRRRKMKR-THIEVIV-------KEK---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRLIQQR-------------RGRGTPTYKSLKHRSK- GKAGN-----ARLTNE-TAKAE----IIDIVDCPNHSAPLLKLKHENGEK-RLNIAPEGV KVGDYIESGE-------------NIA---IKPGNLLSLRQIPEGTLIYNIEKLPGDGGRF VRSSGAFAKVASK-LK--N-KAIVLMPSKKQKEFGLNCRANIGTVAGGGRTEKPFLKAGS KYYAMKAKNKLYPHVSGVSMNAVDHPFG-GTSSSHK---G-I----PTQSGRNDPPGRKV GMLSPKRSG-------RKKR---------------------------------------- --MTEQQTK-------------------ENKAN----------------------PMRKL KIDKVTLNIGAGKDQAVLDKGLKLIEHI-TGT-KAVQTVTQ--K--RIPDWGIRPGLPIG CKLTLRGK-KA-IELLNILLGGIEHRMNEKQFDDKGNVSFGIKEYIDIPDVKYSPDIPLM GLSVCISLKRA-GFRIKERRITKRKIGKKHMITKEEAISFIKSKFNVKM--GEDE----- --- >GCA_007116795 -----MT-ITKR--KKVRK-YRGSK--THGGGSMKKRR-GAGSRGGRGR-AGSGKRGDSK K---------PSYW-----------------KD-----WEM--G-------TH-GFTS-- HSRS--VT--VA-----M-NVSDLHR----ELPRLVE-QGVA-TK---------KGDIYT VD--LSVLG--VDKLL----GAGHIGVSV-SVSV---AAATPKAKEKVSAAGG------- -----------------------------SVVEEASED---------------------- ---------------------------------------------------------MAI E--------------------RKFVDQNMREFRI----------------KRFVEENV-Q RVGLSDVKLK------KTPLGDKIIIHASRPGLVVGRGGASIQLLTRQLKEEFNLDNPQI EIE-EIANPDLDADIV----------AERVLNTLERFGSGRTKSIGHRAMADTIRAGALG VEIIISGK-I------------PS-------------MRAKSWRFY-------------- ----QGYLKKAGDIAVEGVDKSIKSVTLKSGAVG-------------------------- ----------IRVSIM---------------PPGL----------VLPDNI--------- ------------------------T-L------------T-EQLVTE--VE--EVT---- --------------------------GTPEA----------------------------- --------LETE--EI---------AQ-EPAK---------------------------- ---------------------------ETTTE---------------------AETAEVT TQAEP------------------------------------------------------- ------------SAEDTEPKA-EQ------------------------------------ ---SVSEEQSSDAE---------------------------------------------- ------------------------------------------E-KQ-------------- ----------------------------------------------MKLKILNTKNTQNG DITFP--INE-PLRTDLIKRAIQSLRSRARQPYGADPRAGLKHSTNIRKRRR-V---YRG SYGSGIARSPRKILSRNGRRLNWVGAEAPNTVGGRRAHPAK-----ASKIWERKINKKEN RKAISSAITATLDKEVVALRGHKLP--S---TYPFALDADFDALTKTKDVIAAL---ETL GFADDLTRGAQ--GAKS-----------------LLI-V-T-ESET-------------- -----LTKAAKNISGVDVASARQLNAYMLAPGAHPGRATLYTTQS---IKILSGEEPADS TQKSADSKPKAVKKAANT----KPKAAVSKPKAVKKEAKK-------------------- ---------------------------------------------MAKTNR---FNLPFR RRRQLKTDYKKRLALL-KSRTPRLVVRKSNANTVVQIIEYRPDGDVILAQGSTAQL-AGF GW----KASQGSIPAAYLAGYLAGTRALKA-GVSDVIADLGMQEPYHGGRLFAAVKGALD AGLSVPA--SDSAFPS------EERLSGTHID---------------------------- --ESMPKLVEAVKKK-------------VGA----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKPI-TSSVTEAFQPGSQVATCDNSGA KIVEIISVLN--KKTSKGRRSGAGVGDMCIVTVKKGRPDVRKQ---VMHAVIVRQKKEFR RVDGVHVKFEDNAVVVCKDAK-GNPKGTIFKGPIAKEAAD-RWPGVANVASIIV------ -----------------------MAAKKT---------A-KQVA-----------P---- -E----GQDKGS------------------VSTISLRGQEFVGTVVSAKAHRTVSVAWER RRYVPKYERYEKRRSKVAAHNPDEID--AKEGDVVRIKESRPLSKTKHFVVTEI------ ----------LT---------------------------------------------RKQ E----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKVFTYKGKTLD--------------------ELSTLSRDELAALF DSRARRTMMRGY------PEEWKKAEAKILAKDR-------------VKTH-ARELI--- ------ILPRM----------------------------VGKTVLVHNG--------KEF K-----------EVRIQEEMIGQR----------------------------LGE----- ----------FALTR-NNVRHSN------------------------------------- -------------PGVGA-TR-------------------------------SSSAASVR ------------------------------------------------------------ ------------------------------------------------------------ ------------MPKARIKIASADIDKVNQVCEYIKDISEKTGVDIRGPIPLPTKKLQLT TRKSPDGEGT-------ATWERYEMRIHKRLIDL-GVDERALRLVMRVQIPEGLNIEIEM ME---------------------------------------------------------- -MKQ--TFKRT-----WNKSVQARKQRKYRYN-APLHTQSKF-LHASLSKPLREKH---- ---------------------GRR-SLRVRTGDEVEILRG--SFS--GESGVVEEIDTKR ARLIIRGVAALKLDGS-RKPYP----------VAISNVRITKL-VE-------------- ---------DKR-RI--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MARDRKFVAYRRL--------------- -E-RPYTRKSKYR---RYQYVRGT-PHSKIVRFVMGSR----TKSFPI-SVKLVSKTDL- -QIRHSSLEAARMSANRRL-EKAAGKQ-GYFFRIHKFPHHILRENPLAS-GAGADRLSTG MKKSFGKAVGVAAQVRR-GDVVIEIGC---E-EKHLEVAKRALNIVSSKL--PNGYYV-- ---------------------M-----VDRVPAGSNEVT--------------QTHKRLP KVYE-------------------------------------------------------- -----------------------------M-ALN-NPLANVLSAINNNERVSHKEVTLKN NSKVIRKVLDILQEQGYVSSFEVIENGR-GGELKVLL----------------------A GTINKIGVISPNFPVGKSDYQKYEQ--------------------RYLPARDFGILVVST SKGMMTHMQAKELGIGGRLIAYCY------------------------------------ -MKATI------------QEQVPIPEGVTASYQNN-----VLVVE--GKAGKVERTLI-Q P-G----IAISV-KDNV-VHLD---AP-NAT---QREKRHLYTMRSHIRNMLQGAQEG-H TYKLKVCSGHFPMNVSVS---GDK--LT-VKNFLGEAVPRVLSLK--QGAVVKLDGD--- ----IITVSAPSKEIAGQQAADIEQLTRITN---RDRRI----------FQDGLYIVEKD GRPIL-------???????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????--------- -----MGYKYAYQ----------------------------------------GDTQSTA R----------------------------------------------------------- -----------AAQTNVA-VSTKSAIMVANFV--RGKSVERAQRDLGLVLAKKIAVPFTR FTD-GAGHKP-----G-----IGP-GKYPIKASEYMLSAINSAAANARDKGL-G-DELTI VSVTVHQAARQMRY------------GR--LRGRQRKG-THIEVVV-------AEAEEKK ----TRKPATK-------------------------------AKPKAADS---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKPIIPQK-------------RGKGSPSYTVTSHRFK- GQAKH-----FADG-----EGQ----IVDIIHCAGHTAPLALVEHEQGLL-YLTIAGEGA SVGEIVQIGQ-------------DAE---LKVGNTLMLQDVPEGTPVFNIEGQPGDGGKF VRSSGSAARVVTK-TA--T-HVTVALPSKKQRTFSAKCRATIGVPAGGGRVDKPLLKAGV AFHKYGARNKYWPKVSGNSMNAADHPFG-NTRSMRK---S-K----SKPAPRDAPPGRKV GMIRPRQTG-------RK------------------------------------------ -------------------------------MN----------------------VMKTL QIDKVTINFGAGKDQQRLEKGMQLIQMI-TGK-TPVKTITQ--A--RIPGWGLRPGLPVG LKLTLRGE-EA-KSVLSRLLEARENRLKESCVDNYGNISFGLSEYIDIPGVKYDPKIGVI GIQASITLTRP-GYRVSRRKLRSTSIGKHHVVSRQEAKEFMEKHFSVEF-VQ-------- --- >GCA_003648985 -----MV-VHRR--KKKVK-QRGHK--THGWGSKKKHR-GAGNRGGRGM-AGTGKRGDQK K---------PSIWA----------------KR-----Y-F--G-------KR-GFKPKG IIRK--AT--NP-----V-NLLVIEA----RIDEWLK-DGIA-KK---------VDDVYE VD--VRKLG--YDKVL----GYGKLTRKY-RIIA---PAFSEKAGKKLKSAGG--EAV-- V---------------------------EK------------------------------ ----------------------------------------------------------MI E--------------------RKLISERGKDFQI----------------EEFIMNSF-Q NVGISNVKVQ------RTPLGEKIVITALRPGLVVGREGQNIRRLTAELKKKFGLENPQV EIQ-TVDSPFLDPHIV----------AEKIANTLERFGITRFKAVGHRAVQDVMNAGAIG VEIIISGK-V------------PS-------------RRAKRWRFY-------------- ----AGYLKKCGDIAIEGVKKAYAIARLKPGVVG-------------------------- ----------IQVRIM---------------PPDV----------RLSDKI--------- ------------------------K-I--------------------------------- ------------------------------------------------------------ ---------GEEVE-----------EVKVEEK---------------------------- ---------------------------DENKG---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------TE----------------------------------------- --------------------------------------------SSE------------- Q---------------------------------------------MKVDVVDLGGKVVG KVDLPKQFSE-EYHPNLIKRAVEVIQANKRQPYGAKPEAGKRAIVKLSKRRR-D---YRA SYGRGISRVPRKVLLKRGSQFYFVGAFAPGTVGGRRAHPPK-----AEKDWSKRINKKER KKAIRSALSAALNKSLVEERGHKLP--E---KYPFVLVDDFVKLGKTKDVKQAL---EAL GLKDEIERSAK--KKIRAGKGKLRGRRYRRKVGPLLV-V-H-EKCD-------------- -----LMKSAANIPGVDIVLVNNLNAEMLAPGGKAGRLTLFTKSA---LDVMAKENLFM- ------------------------------------------------------------ ---------------------------------------------MKRKDKI--FTVQFR RKREDKTNYRKRIELL-KSGKPRLVVRPFLKNIIAQIIEFDKVGDRTLVSATGYEL-EKF GW----HFSKGNIPAAYLTGLLVGKKGLKK-GIKEAVLDIDGKTPLKGTRVFACLKGAVD AGLVVPH--SEDVFPS------EERLRGEHIKGYFELGKWNS--ESQFAEMK--K--KGV DLGKITDVFEEVRKKI------------MEM----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKPV-KARVTKGINFGSYIPVCDNSGA KVIRMFAVFR--RKTTKGRYPSAGVGDMIMATVKEGKPEMKKQ---VVLAVIVRQKKEYR RPDGMRIAFEDNAAVVVKDKA-GNPKGTLIKGPVAKEAAS-RWPGISKLANIIV------ -----------------------------------------MAE-----------C---- -K----DKKCPF------------------HGNVKIRGRKLKGVVIAKDLHRSATVLIER MKYLPKYERYEKRLRKIRVHNPSCID--ADVGDEVMIAETRPLSKTKHFVII-------- --------------------------------------------------------AKK- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFTFRGKTLE--------------------ELKQMTLDQFAELL KARQRRKLKKGL------TEAEKKLLKRIREKPD-----------KKIRTH-CRDMV--- ------ITPEM----------------------------VGLTIYVHNG--------KAF V-----------PVNVTLEMLGHR----------------------------LGE----- ----------FALTR-KPVKHSA------------------------------------- -------------PGVGA-TR-------------------------------SSAAVSAK ------------------------------------------------------------ ----------------------------------------------------------M- ------------PQKARIKIVSTDINKINQVCQYIKDIAEKTGVVMRGPIPLPTKRLRVT TRRSPDGEGT-------ETWDRFEIRVHKRLIDL-GIDERALRLVMRVPIPEGLHIEIEM VE---------------------------------------------------------- -MKK--RFSRE-----WIKSKQPRKQRKYRYN-APLHIRGKL-VHCHLSKELKKKH---- ---------------------GKR-ALRLRKGDKVKIVRG--EFK--GTVAKVARVDLKR MKVYLENVMRERRDGR-KVAVP----------FDASNLMITELNLE-------------- ---------DKM-RM-----------------------------------RR-------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MARLRKGIAYRNL--------------- -E-RPYTRVSKFR---EKSFIRAT-PRVNIIKFTMGDP----NGKFEY-RLDLVSKDSI- -QVRHNALEASRLTVNRHL-EKKLGKK-GYHFKLRVYPFHILRENPIAA-GAGADRVSKG MKQSFGKPIGSAAQISA-GQSIMFVDV---N-KADIPVAKTALERAIKKL--PCKCTI-- ---------------------K-----ISEIKA--------------------------- ------------------------------------------------------------ -------------------------------MLN-DPLADALSKVLNAEFAGKKECIIKP YSKLIKAVFKIMQREGYVGDQKEVDDGR-GGYLIVNL----------------------I GAINKCGAIKPRYDVGIDEFEKFEK--------------------RYLPAKDFGFLIVST SKGLMTHIEAKKAGIGGKLIAFVY------------------------------------ MK-ETI------------EVKLDIPEGVSVSYENG-----VVCVK--GPLGELRRSLF-Y P-G----VDVKV-GD-K-VVIM---SE-KAT---KREKKMIGTFRAHIRNMFKGVTEG-H VYKLKVCSGHFPMTVSVE---GNE--LV-VKNFFGEKVPRKLKIP--NGVKVKVEGN--- ----DIVVESTDKELAGRTASDIEQLTRRVG---FDRRI----------FQDGLYIYYKD GKYV-------------------------------------------------------- ---------------------------MPKKRSPRKGSLQYWPRARAKKIRPRVRKI-S- --LD-----KAGLSGFAGYKVGMVHVCLLDERKNSMTK--GERITVPATIIECPPLRIFG IRFYKIK---DGVLF---SGETVLNPKLDKI-----L-----SRIV-------------- ----QLP---K--------KKIKA-----------------------IDEVK-------- ---IE--DYDDLAIIVYTMP-----KLTGVRKKKPELFEMSIGGKDIK---EKVEFVKGL FDK-EIKVSDVFGEGALVDVHAVTKGKGFQGAVKRFGVAIRQH--KSEKTKRG--PGTL- GPWT-PKRVS-WTVPQTGKMGFHQRTEYNKLILKIG----KAE--EINKPGGYLNYGVLK CDFVLLKGSIPGSRKRLIIFTAAKR---P-N--DKL-LMVP-KIEKIIK----------- ------------------------------------------------------------ -----MRFNYST----------------------------------------KYDAEKEA R----------------------------------------------------------- -----------AIGLGMR-ISTKHSVEVCRML--RGMELQKAKDLLQKVLEKKVAVPYRR YRR-DLGHKK-----G-----IEA-GRYPEKVCKEILKLLKDVEANAQVKGL-NTANLVI RHIAAHSGGKPLKH------------GR--KRGRTAKR-THVEIIV-------KEK---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKSLIVQR-------------RGKGTRTFKALSHRYK- GDAKF-----LSLAEG-KLEGV----VVDIVDCPGHSAPLMIVRYANGNE-ALMIAPEGI KVGDMVEIGS-------------GAS---VKIGNVLPLDEIPEGTSVYNIESIPGDGGKF CRASGSFARVVGK-LP--S-GVLVKLPSKKERLFNANCRACIGVVAGSGRLEKPFLKAGN KAKAMWARNKIYPRTSACKMNAVAHPFG-NTRSARK---S-K----KRPVSRNAPPGRKV GSIAARRTG-------RKKR---------------------------------------- -------------------------------ME---------------------NPMREI RIEKVTLNIGSGKNVDALEKAIKLLQKI-TGA-KPVKRVAK--K--RIPAWDIRPGVPIA CIVTLRGK-KA-RQVLGLLLDAKDRMLDAKNFDN-GTFSFGIPEYIEIPGMKYDPELGII GLEVAVTLERR-GFRVKRRKLRKRRIGKRHRITKEETIAFAEKELGVRI-K--------- --- >GCA_015122025 --------------MKSRK-LRGSS--TAGRGLGKRSRSGAGRRGGRGR-AGGGKR---- -------------------------------------------G-------QQ-NFASIK FYLK--ET--KAEKKMPL-NLSYLQS----HLDKLKR-KGII-QE---------KDGKLV VD--ITSGG-EYTKICGKFKGQGLKLSVY--------GKTSKQAKENILQNGG--EVN-- ----------------------------E------------------------------- ------------------------------------------------------------ -----------------------MINALMKEQVT----------------RDYLFKLF-S KFGISDIKLE------KTPLGERVVIRTPKPRAIINRASNELRIASKKLGEIFEQSPPRI EVE-ESEDPMLDPNVV----------ADALAFRVARFGPLKYKVIAHKMLDSIMSAGAIG AEIEMGGV-IK--------------------------ERAAHFKFRP------------- ---NGGILPKSGQIEDYGVRKGQKQLLLKRGVIG-------------------------- ----------IKVTIV-----------------------------TKSSKLGGI------ ------------------------N-I--------------------------------- ------------------------------------------------------------ -------------------------SDGRENR---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------GP GDGASKDEHKEDTGSAAS------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MKKAIVLSLSGQKAS EIELPDVFEY-RVDKDLIKKAFLAEQSAKFQLKYTDPLAGKRKSSTLSKTRR-T---YKT VYGHGLTRTPKKVTWHVGTQFVYIGATAPNAVGGREAHPPQ-----QNKTLEKKINKKEK IAAIKSAISSSANADIVKSF-HQIK--NF--ELPLIVEDKINDITKTKELYKVL---SSL GLDAETERAKR--KNIRAGKGKMRGRKYKKKLGMTII-T-T-EPTK-------------- -----LRKSAANL-NINVVDIKNLNIEDVSHAGKPGRLIVWSQGA---VSSLKL------ ------------------------------------------------------------ ---------------------------------------------MVKVNR--------- -----RTNYRARLGML-KSKLPRLVVRKTNSMIIGQIVEYEKSGDKTLSAVYSKEL-RAY GW----NFGLKNSPAAYLAGFLLGKKSSAK----EAILDKGSSTLKKDSFIYYFMKGASD AGIDVHT-KEFDI--------TEDRLFGKHIIEYASKGTTGN------QFSSVGK----- AINNMKDEFDTVLKKL----------NEYGK----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKPM-KAAISKPINVGSYISVADNSGA KIAKVINVRG--YHGVKGRQPRCGVGDTIFIVVKKGNQDVIHK---TFPAVIIRQKKVFR RLNGLRLSFEDNACVLVKEIDKYEPLGTAIKGPIPREISI-RFPNVSKVAFKVV------ ----------------------------MQ---YDDLVK-PEVE-----------C---- -N----DKNCPY------------------HGTLKVHGSRFEGVVVSAKSKRTAVVQWIN FERLKKYDVYREKKTRVLAHNPDCIS--AKVNDRVVIYETRPLSRWKKFVIVRK------ ----------I------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------MEEFKFKSKSVE--------------------DLSKMPVNQLASVV NSSLRRRMKRGF------TDQQKKLIEKVEKAKKNG---------KPIKTH-LREMF--- ------ILPSF----------------------------VGITINVHNG--------KEF V-----------PVAIKPDMVFHR----------------------------LGE----- ----------FAITV-KQVRHGT------------------------------------- -------------PGLSA-TR-------------------------------SSSFVPIK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLTSTDTKQLKVVCDQIADISRKLGTSIKGPIPIPTKRIRVT TRRAPNGSGR-------ESYETWELRLHKRVIDM-QADPKALHLIMKTPIPKEVNIEMEI MGP--------------------------------------------------------- -MKD---FSKH-----WNGSKSPRKQRKYRAN-APLNLKHRM-VSAHLSKELRQQY---- ---------------------HTR-SFPIRKGDTVLVMRG--KFK--GSEGKVEKVYTKQ LRVTVDSAKITSKKGT-KIPIK----------IRPSALLIKELNLS-------------- ---------DKL-RE-----------------------------------KSLAKYGK-- -----AR----------------------------------------------------- ------------------------------------------------------------ --------------------------------MAKLRPGRAYRSM--------------- -K-QPYTRKSKFK---EKNYTKFA-LHTKITQFHSGNM----HNTFKK-RVEVISKSTL- -QVRDNALEAARIVANKYL-TDSIGEE-NFHIQLVSIPHHILREHKLAT-GAGADRFSAG MQKSFGKPIGLASQISA-GDKVFEIFV---N-EDHVNEAKEAADKIKKKLGFKTLALV-- ---------------------------I-------------------------------- ------------------------------------------------------------ --------------------------------MT-DQVSNALNVIFTSKISAKKECIITP MSNFILKILDIMNKGGYIDKYEVINDAR-GGFIKVTM----------------------N ENLNKCKSIRPRLPVKINEIQKYEE--------------------RFLPAIGFGMLIIST SKGLMTNAEARQNGIGGNLIAYVY------------------------------------ -MSTKF------------STQL---DGADVKIENG-----EISVS--GPKGELKVKVV-Y S-----FLSVRK-EENT-LYIE---CK-KDT---DYQKAIAGTLAAQVRNMVKGVKEG-Y TAELELVYIHFPASMKLV---GDK--LV-VENFVGERKAREIFIP--KDVKTKVQGT--- ----KIILEGIDKYKVGQVAGTIEKNVQIKN---KDRRV----------FKDGIFIVKKP E----------------------------------------------------------- ------------------MG----H-QITKKSTPRRGSLQYYPIRKSKRPFHTLRAH-A- D-LE-----KDELSTFAGYKVGMRQAVYIDNDKNSPTF--KTELLSPVTILEVPPLLVVA ARFYKDN----------MSIGEVWAEA-DKN-----V-----GRRV-------------- ----------K-------FKPNNA----------------------NLEELLK------- -------KASDVKLLVSTTP-----WKINL-KKTPEIFEIESGGTL-E---QKAERAKSL LGK-EINASDSIKEGTFVDIGGVTKGKGFTGSVKRFGVKIYPV--HASKSRRK--AGNL- GAES-MAKVQ-FTVPQHGRLGFNSRTEFNKLVLKILN---DPT--EANIPQGYYRYGNLS APAIVLKGSVPGSTNRLLILRKAIR---P-N-KKLG----PTKVTLI------------- ------------------------------------------------------------ ----------------------------------------------------------MI K----QVS---------------------------------------------------- -----------AKSERVQ-VSLKHVHEIMESV--TGKNLDKAIKHLDGVLEEKRFIPFNK YG--GKGHKS-----GVP-------RGYPKRATKFVISLLKELKSNAKNINL-DEASIII KKYSLGRGKYPRFPSG-----AVYRHGKF----------TNLVVFG------EAEAKAPK ------------------------------------------------------------ ----------------------------------EEKKASA------------------- P----------------------------APAVEATNEKKE--------ENNNDATKEND ------------------KRTDEGAG---------------------DKGLPVQALQ--- ----------------------MKVPRSRR-------------RGK-SRIFRANTFKAI- ADTRI-------ISSNNAMNFK----VEDIIHDSYRTAPLMEIRFEDGTV-SYLPAFNGA YVGQILTFLK-------------GGD----KTGSIDSLKNIPTGANVYNVELRPNDGGKL VRSGGLSAKVIKK-EK--G-IVSIQLPSSRIIDINENCRAVVGVISNSGRMNKPLYKAGN NYHLKRARGRYWPLSAAVAMNAYEHKFG-GKRRSSQH----K----SKSVSRNAPPGAKV GTIAPRRTG------VK------------------------------------------- -------------------------------MNK-------------------DNKMRDI RIEKVTLNVGVGKAGAELDKIENLLKSI-AGA-QPFKTTSK--R--RIPEWGVRPGLEIG TAVTLRGK-AA-EEILGRLLEGIDKKLSKSKFDEGGNFSFGIPEYVHIPGVKYDYTVGIV GLSVAVTLFRP-GFSISRKRVR-RTVGKSHRIKKEEAINFISNKYNLQV-SD-------- --- >GCF_018433835 -----MP-VNKR--SK----YRGSR--TCGGGTHKNRR-GAGNRGGRGR-AGQRDHRFSH FYL-----KGEI--------------------------S-N--G-------KH-GF--IN KTSV--PV--SA-----L-DVGEIDQ----MADALLR-EGLA-SQ---------EGDLIT LD--ATEIG--IEKVL----GGGRVTHKL-SISA---RGFSERARAKIEEMGG--QAT-- TV---------------------------------------------------------- ---------------------------------------------------------MAI E--------------------KKFIAEGVRNVRV----------------EKFLTKEL-K RAGYGGMDIT------RTPLGTQVTIFAEKPGIVIGKGGKQVRQLTQDLATVYEIESPQV EVQ-QVTNPNFNAQIM----------AERLANALER--GWYFRKAGQSTIRRIMESGALG CEVVVAGK-L------------TG-------------ARSRTQKFT-------------- ----EGYVKHCGEPSETIVEKGYAIAIKKLGTIG-------------------------- ----------VQVKIV---------------PPDA----------RLPDAF--------- ------------------------D-V-------------LEPAPKKA-PAEPIEA---- ------------------------------------------------------------ ----------EEVG-----------EDVFE------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------EEFEETSGEEY---------------------------------- ----VEEER--------------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MKAQVRTLTGEIAH EIDLPEIFTE-EYRPDLIKRAVLALQSTRFQPHGTNPYAGMRTSAESWGSGR-------- ----GVAQVPR-LKN------GSRVARVPQATGGRAAHPPK-----VEKILVKEINRKEK QKALRSAVAASTYLDLVRERGHLFE--G---DLPLVFEDRFEEITRTGDVISAL---SAL GVYADVERAKSS-KKVRAGRGTMRGRRYKQRKSVLIV-T-G-SEP--------------- ------LRAARNLAGVDAVTVSQLNTELLAPGTQAGRLTIWTESA---IRRLEEFS---- ------------------------------------------------------------ ---------------------------------------------MATGPR---YFVPFR RRHEGKTDYYKRMSLL-SSGTPRMVVRRTNRQIIVQLVVPEIEGDRTLVAAYSAEL-AGY GY----EGTTASTPAAYLTGMLFAVKALNA-GYEDAILDIGLARAKPGARVFAALKGAVD AGLDVPY--GESILPD------EERLKGAHIAGYAPE----------------------- RAGDLVANVEAVALAI------------KKELV--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAM-QSTIPRALATGSRMVCSDNTGA RLVEVISVDG--YHGVRRRQPCMGVGDVATVSVKKGTPDMRRK---LEKAVVIRQKKEIR RPNGIRLSFEDNAMVLINER--GEPKGTEIKGAVPREIAE-RFPKIASMATIIV------ ------------------------MARNIG---LD-VPI-PEAE-----------C---- -E----DANCPF------------------HGTLPVRGQVITGKVVSDRMNGTVVVEREF LHYVKKYKRYEKRRSRYHAHSTPCIN--AGVGDVVRIAECRPLSKTKNFVVVEV------ ----------MK---------------------------------------------E-- ------------------------------------------------------------ ------------------MAKKTQK----------------------------------- ------------------------------------------------------------ ---------RMPRRREEFTYRGYSVE--------------------DLKQMALSELLPLM PARARRKFDRGL------SREHEKFLADLRSGDAK------------IRTH-LRDMI--- ------VMPEM----------------------------VGRTIEIHNG--------KEF Q-----------AVEIQPEAVFHY----------------------------LGE----- ----------FALTR-RRVSHGS------------------------------------- -------------AGIGA-TR-------------------------------SSKYVPLK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIRLSGTDFEKLEMVCDRIKEIAERTGVNLAGPIPLPTKKLVVP TRKSPDGEGT-------ATWDRWQMRVHKRLIDI-DADERALRQLMRIQVPKDIGIEIVL ES---------------------------------------------------------- ---------MV-----RIVSKQPRKQRKARYN-APNHTRGRF-LSASLSPELRGKY---- ---------------------DAR-RARVVKGDTVKVLRG--DFA--GDEGVVDAVDMKM CRLIVHGVMVTKADGT-EVPRP----------VDPSNVQITKLNLK-------------- ---------DKL-RE-----------------------------------ERLGGGA--- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MV-RKPAKMYRNL--------------- AK-KAYTR---------REYMGGV-PGSKIVQFDMGNL----TENYPV-ELSIVADETC- -QIRHTALEAARIGINRQL-VKEVGRA-NFHLKIRTYPHHVLRENKQAT-GAGADRVSEG MRLAFGKAVGTAARVEK-GQKVFSVWT---S-PQHVEKAKASLKRGIYKL--PTPARI-- ---------------------V-----EERAPTA-------------------------- ------------------------------------------------------------ -----------------------------M-ARL-NPIADAMSTIKNAGDAGKNEVIVEP ASKLLGAMLRVMQENGFIGGFEFIDDGR-GGQFRVQL----------------------S GTINKCGAITPRFPVAMADMEYWES--------------------QYLPAKNFGILIVST SKGVVSHAEARSEGIGGQLLGYVY------------------------------------ ---MGI------------TRQVEIPPGVDVTLEGS-----VLTVS--GPKGTLIRDMR-F P-Q----INLKV-EDSE-VVVS---TA-SDK---KRILAMTGTIEAHVKNMIRGVADG-Y EYRMKVVYSHFPIQLRLQ---GNR--LE-INNFLGEKQSRIAKII--EGVTVKIGND--- ----EVTLTGIDKEKVGNTAANIEHATRITK---RDPRV----------FQDGIYITERA ------------------------------------------------------------ ---------------------------MPKINRPRRGSLAYSPRKRAKSPVPRYGSW-P- E-YTG----APAVQGFAGYKVGMTHVIMVDDHKSSPTE--GKDVMVPVTVVEVPPMRVAG VRAYSED--TYG-KH---ALTEAWTTGLDEE-----L-----SRRI-------------- ----NVP---KNH------DTAAA-----------------------LDAIRNA------ ---VGEGRVAELYALAYTRPM----ELTGVPKKVPDLMEMRIAGGSLD---DQIAYAADI LGK-EITISGNLEVGEYVDVTAVTTGKGTEGPVKRWGVQVRKR--KHSRGGKKRHIGNL- GPWH-PHHVR-WQVPQMGQMGYQQRTEFNKRILKIGT---DGD--DITPAGGFLHYGLVR GPYVLIKGSVPGPNKRLVRIRSAIR---Q-G-EHT--VRTP-TISFVSVQSQQG------ ------------------------------------------------------------ ----MARTDYSAK----------------------------------------IGGENVA R----------------------------------------------------------- -----------AKANELP-VSPKHSIEIARFI--RKMTTTEAKAYLADVVELKKAIPFKR FNR-NVAHKR-----GLS--KWPA-GRYPVKAAEAYIRLLESVEKNAEYIGL-DVENLRI DHVAANTGRGLRAFFP-------RAMGR--ATPKRRET-VNIEIVV-------TEVA--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MAHRIIAQS-------------RGKGGPSYRAPSHRYK- AELRH-----V-GKNDALVSGS----VVDIEHDPARHAPIALARLESGEK-VYVLATEGL GVGDAVSWGT-------------GGA---VKNGNTLPLREIPVGAYVCNIEARPNDGGKF VRSSGVQALVIGK-AED-G-RVGVRMPSGKNKWFNGACMATVGIVAGGGRGEKPFVKAGK KHFHVRSSSERWPRVKGVCMNVIDHPFG-GGGHQHC---G-R----PKTVSRGTSPGRKV GHIAARRTG-------KWKK---------------------------------------- -------------------------------MS----------------------AMKDV YIDKVVVHMGVGESGERLVKAEDLVKQI-TGQ-KPVRTIAK--R--TQPAFGIRKGAPIG CKVTLRRE-NA-EKFITTALGIVERQLAPSQFDRTGNVSFGIEEHTDFPGMSYDPTIGIY GMDINVVLEHK-GVRIARRSVERRKLPEAQRVSKEEAIVFMRERYQVEV----------- --- >Bin595_genes -----MT-THKK--PKDCR-LRGST--SHGYGSMKKHR-GAGSRGGRGR-AGSGKRGDQN K---------PATWKN---------------KN-----Y-F--G-------KY-GFTS-- RSRT--PS--SF----TI-NIKSIED----RAETFIK-KGLA-KL---------KNDFLE IN--LADIG--YNKLL----STGKPKRKL-LITT---MHATEKAIEKIKAAGG--EV--- -----------------------------KLTSQKPDKKKDEEA---------APVAE-- ----------------------------------------------------------MI E--------------------RQIVASNVKELAI----------------QEFISKQL-K NLGHSHIKLL------KTPLGEKIIIHASRPGLIVGRKGQNIKKLTEDLKANFTLDNPQI EIS-EVEQPDLDAQIV----------AERIASSLEKFGTQRFKGVGHKVLGDVMNAGALG VEILITGK-I------------PS-------------SRSKRWRFY-------------- ----QGYLKKCGDVAIVGVRRAYAAALLKTGTVG-------------------------- ----------IQVRIM---------------PPDV----------VLPDRV--------- ------------------------K-I------------Y-MEEA--------------- ---------------------------EAEK----------------------------- --------LKEELKAKSAKKTEN--NEENVDK---------------------------- ---------------------------KEEKE---------------------EDKKSVN VEAK-------------------------------------------------------- ------------VNKEEVKEEPKKEEP--------------------------------- -----KEEPKEEPKEEPKE----------------------------------------- ------------------------------------------EPKEE------------- PK--------------------------------------------MKIKIFDLNNAEKG SKELPQVFDE-QVRPDLIKRAVETLQANHRQPYGSDPHAGKKCSAELSRRRR-K---YRG SYGHGISRVPRKILSRNGTRFNWVGAFAPGTVGGRRSHPPK-----ASKIWARKLNIKER RKAIRSAIAATIGKEFVIQRGHALP--D---SYPFIIVNDFESIDKTKSIVDAM---KKL GLEAELSRASE--KTYRAGKARLRGRKYRKRKGPLFV-V-S-KDCP-------------- -----LLKSASNVPGVDVVPVNELNAELLAPGSVPGRLTFFTEAA---VERLGTENLFYS RP--------------------------------KEKKE--------------------- ---------------------------------------------MARTKYGKTRTVKYR RKRESKTNYKKRLALI-KSGKDRLVIRKSLNIITVQIVRYNPDGDKVLLTSTSKDL-HKL GW----KLHKANLPSAYLTGLLLGTKAKAK-GIEEAVIDLGLQIPIRGGRLFAALRGAID SGLKITH--SVEALPS------DERISGKHIEEFAKILKE-DKARYEIQFSSYIK--DGV DPQSISKLFEDTKKKV------------SSQ----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MQAN-KATVTRGLQTGSTLSTCDNSGA KVIRIVSIKR--KKTTKKRVPYCGVGDLVLASVKKGKPEMRKQ---VVFAVIVRQKKEYR RPDGMRIKFEDNAAVVLKDDK-GNPKGTIFKGPIAKEAAA-RWPGVSKVASMIL---M-- -----------------------TRTRNIG---LG-TKL-PSTA-----------C---- -S----DKNCPY------------------HGNIKIRGKQFTGKVVSDKMTRSVLVEWLG WQKVPKYERYRKTKTKVSAHNPACID--AKEGDMVRIGECRPISKTKTFIVVSV------ ----------LG--------------SDDTHQL------------------------KKE SLEEGK-------HQDKPK-TEINTKTENASE---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MVKKEFLYRGKNME--------------------ELQEMGIKELADLL PADARRKIKRGF------TDQEKILLRNLRKSTK------------PVKTH-CRTMI--- ------ILPEM----------------------------VEKTIKVYNG--------KSF E-----------EVIVQPEMIGHY----------------------------LGE----- ----------YSHTR-KRVAHSS------------------------------------- -------------PGVGA-TR-------------------------------SSSNVSVK ------------------------------------------------------------ ----------------------------------------------------------MD G--------TRKMQKARIKLTSNDIGKINDVSSHITEIAEKTGVTMRGPIPLPTKKLKIT TRKSPCGDGK-------ATWERYEMRVHKRLIDL-GLDERALRLVMRVQIPEGLKIEIEM ID---------------------------------------------------------- -MKQ--AFSTN-----WNSSKRPAKQRKYVYN-LPLHTQSRI-LSVHLSSDLRKKH---- ---------------------NTR-STPVAKGDKVKVLRG--QHK--GRENKVERVDHKK TKVYIMGIETTKKDGS-KSAYP----------IKPSNIMITELNLE-------------- ---------DKK-RLA----------------------------------SIERKGAK-- -----TNKTESAPV---------------------------------------------- -------TEEKRNEDHEE------------------------------------------ --------------------------------MARLRKFSAYRRL--------------- -E-RPYTRISKFR---TKSYVRAR-PNCKIVRFDMGDL----SKSYQY-TIKLRSKNAL- -QIRDNAIEAARQTSNRIL-QKRIGKT-GWVMRIRMFPHHILRENPLAS-GAGADRMSTG MKCSFGKAIGIAARIRE-GQTLFQIET---N-KSNTAAAKQALRRASSKL--PCST-M-- ---------------------IE----VIEKPAE-------------------------- ------------------------------------------------------------ -----------------------------M-SLN-DPLSNVMSKVNNYEKVGKKDCVIKP VSIIIKKLLDLLNQEGYMGKYKEFEDGK-GNHLKLDL----------------------L GNINKCGSIKPRFSVALDDYEKWEK--------------------RYLPSRGFGILIVST SQGIMTHNKAKEKKIGGRLLAYCY----MED--SWHTVT--------------------K MVLENI------------EKEIEVPENVEITIDGI-----VVKAK--GVKGDIERKII-M P-K----IAISV-VDGK-VKVG---AN-KAT---KREKAKIGTAVAHITNMIKGVDEG-H HYELKICSGHFPMNVSIS---GNK--LV-IKNFLGEKVPREIKIK--EGAKVKVDGD--- ----KVFVEGLDIEIVGQVAADIEQLTRVTN---RDIRI----------FQDGIYIIKKP KKRML------------------------------------------------------- ---------------------------MPKAHRPRHGSMQFWPRVRAKREYKRVQTF-S- D-SK-----DANLMGFAGYKVGMTHIIITDGRKTSITK--GEDVTIPVTIVECPPLRIAG VRFYTKK--YKT-IQ---PSGDVMAKV-DKA-----L-----ARKI-------------- ----TTP---N--------KAPAD-----------------------LDSI--------- ----K--EFDDLRILVQTQP-----KMVGVGKKKPELFEVTIGGSK-E---EKLSFAKEH LGK-ELSVKDVLNEGQFVDIHAVTVGKGTQGPVKRFGVKIRHH--KSEKTKRG--PGSL- GGWKGQAHFM-YRVAHAGQMGYHNRIDYNKQIMMIGD---DYA--KVNAEGGFIRYGTVK NPYVLIKGSIPGPSKRIVRMETALR---P-D-KK-A-DTTPQTVQYISTKSKQGN----- ------------------------------------------------------------ ------MTEYAFQ---------------------------------------GFDKERMS R----------------------------------------------------------- -----------ALGRDLA-ISTKQAIEICNYL--RHRKTGQAKMFLDGAIEKTHAIPFKR FTN-GLGHKP-----G----KMAA-GRYPVKSSRAFLKLIESVEANAQTKGF-NTGDLEI IHLCAHKAARPVHH------------GR--HQGREFKR-THVELVV-------TEVVESE ----S----KKGKKAAKVKAK--------------------TNVEEKSSEELKS------ -----------DIADESSNESIDEKP--------TDEK------------IEE------- ----KLADVDSKVEEH---------------DFENKEPNKE--------EKPTGPEDTQA ------------------VEQEASP--------------------------DKEAEK--- ---------------------MGKRLIQQA-------------RGKGGPTYRAPSFRYV- GKAKH-----VRTADE-SLKGQ----VLDIVHCQGHSAPLAQVTFNNGDK-CLMIASEGL KVGQSIFSGP-------------DTE---SNSGNTSPLMDIPEGTMVYNIEGMPGDGGKF VRSSGTFAKIVGR-FK--D-NVIVQLPSKKRKSFHPKCRATIGVVAGGGRLDKPILKAGV NFYKMKAKNKLWPKVSGSAMNAVDHPFG-NARSSRK---S-K----AKPVSRNAPPGRKV GMIAPKQTG-------RKKRS--------------------------------------- -------------------------------MN----------------------KTREI KVEKVTLNIGAGKSTDRLDKGINLLEML-TDV-KPVKTITT--K--RIAGWGLRPGLPIG CKVTVRGK-KA-SELLKQLLGALDNKLNQKQFDDEGNFSFGVKEYIDIPDVEYNPDIGVI GFQVCVTLSRQ-GFRIKRRRLQKKKTGSKHKITKQDSIDYLKSNFNMIL--AEE------ --- >GCA_003557205 -----MA-YNKR--KKNSR-QRGSW--THGWGSKKKHR-GAGHRGGRGA-AGSGKKGDAK K---------PRYWKE---------------KY-----F----G-------KT-GFT--- -SLK--KI--NSKE-KPI-SLSMIRD----QLDKWVA-QGLA-VK---------DNDSFK ID--LSGMG--YTKLL----GTGKINSKL-SITV---PHASGKAKEKVEAAKG--TI--- -----------------------------SIS---------------------------- ----------------------------------------------------------MA QKEAIKTKKDEFDPHKNISVVNIVVSTSLEHDIP----------------LEKMAATL-S NTEYNPEQFPGLVIRIKDPKTSSLIFSS---GNIVCTGARSLDKVDESIQ---------- ----------------------------RIIESVEKI-GIKIKIKPKINVQNIVASGNIG MDLNLNTLAMKLDNTEYEPEQFPGLVYKLME------AKAKFLLFS-------------- ----NGKIVCTGTKSKEMVHKAV------------------------------------- ------------------------------------------------DML--------- --------------------------I--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --ANLKKLKK-------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------STRKYI NITLISI---------AMKSVSLILVEPSTQ----------------------G------ ----NIGAVARSMKN---FGFSKLVLVSPKCELGEEARKRAKNAQEILKSIKIKRSLSES IKGFGLVIGTTSR----TGKDYNMP------RSPLLIEAAAKKIVESNARTAVLLGSENQ GLSTEVLKKCDY-TITIPSASKYRALNLSHAATIILYEL-S-KAKNSALIMEQHKHASPR EKEEVLKQLRRLINNTSFMTSHEKKTQEIVWKKIIGKAQPTKREAYALIGFLKKQK---- ------------------------------------------------------------ ---------------------------------------------MKQKTT---YTVRHR RRREGRTNYKKRLELL-KGRQDRLVIRKTNKHIIMQLVRYSPDGDQVLLTANSKEL-EKK GW----KHSLKSIPAAYLTGLIAGKKAKEK-KAASAILDIGLYSPLKGSRIYAALKGAID SGLKIPA--GKEIFPG------EKRLKGEHIASYLE------------------------ KHKSITQDYEKIKSEL------------LK------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------VKMKSI-RAKIPKSLPHGALVDTCDNSGA KVLKIFGVKG--HKTVKGQMPSARIGDMVKASVVKGRPDMRKT---VVLAVIVRQKKEYM RPDGTRVKFEDNSAVVVKDDK-GNPKGTILKGPVAKEACE-RWPGIAKISSMIV?????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????????????????????????????????????????????-------- ------------MQRARVKLASTDINKINATCDYIRDIAEKTGVVLRGPIPLPTKKLRVT TRKSPCGDGT-------ATWDRFEMRVHKRLID--------------------------- ------------------------------------------------------------ -MKS--EFSKT-----WKSSTQPRKQRKYLKN-APLHTKSKF-LNTNLSKTLREKH---- ---------------------GKR-SVRLRTGDKVRILRG--SSK--GKEGKVESINLKE TKVYVTGIEKPKKDGS-KIKVA----------LKPSNLQIVELKLD-------------- ---------DQK-RKQ----------------------------------KLLVKD-K-- ------------------------------------------------------------ --------EDKKNG---------------------------------------------- --------------------------------MAKLMRAVAWRRL--------------- -E-RPYTRRSKYR---EKSYVRTV-PNNRIVRYIMGNQ----KKEYAY-RVLLNSKADI- -QIRHNALESARLTANKLL-EGK-APS-DYLFKLRVYPHHILRNNPLAA-GAGADRMSTG MAHSFGKPVGIAAQVRK-GQPVLEVNV---N-KERLSIAKQALDRARKKM--PCGFSI-- ---------------------K-----IEEIKAKAQAAN--------------------- ------------------------------------------------------------ -----------------------------M-SLN-DPLANVLSHIYNYEKLGKKELITNN NSKVIKEVLRIMQEEGFIGSYEEIDQGKGGKALKVHL----------------------I GSLNKCGAVKPRFRVKLRDYEKYEK--------------------RYLPAMDFGVLIVST NKGIKTNTQAKKESLGGSLISYAY------------------------------------ -----M------------EDNITAPENCTVTQEKD-----FVVVK--GPKGELKRKLT-D K-K----VEIKQ-EGQD-VLLV---YP-EDT---KRAKRLMNTNKAHIKNMLIGVTEG-F TYKLKICSGHFPMTVNLK---NDV--LE-VKNFIGEKVPRTLKIS--SEAKVSIAGD--- ----DITVEATSKEAAGQVAASIEKLTFRPG---FDKRI----------FQDGIYITEKA GKKIVH------???????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????????????----------- ----------------------------MIKM-----------------------KMKEI KVDKVTLNIGAGKDQRLLDKGVKLIKNL-TGK-DPVKTVTQ--K--RIQGWGLRPGLPIG AKLTLRGK-EA-DEMIKRVLYAKENNLEESHFDNHGNISFGLPEYVDIKDAKYDTEIGMM GLQVSITLTRP-GFRIKHRKIRNTHIPSRHQIKKEEAMSFMKEKYSAVI--GEE------ --- >GCA_002687275 -----MV-VRKR--KKITR-QRGHR--KTGWG--KEHR-GAGQKGGAGN-SASGKRAQAK K---------PSHRGRK-----------------------F--G-------GH-GFTSVK KQLPG------------I-NLGELDS----QLESLTK-KGKV-KH---------AASTYE VN--LATLK--KSKVL----GKGNTTQKI-KL-T---GKASARAKEKIEKAGG--TIA-- ------------------------------------------------------------ ----------------------------------------------------------MI E--------------------RKFVKEKVKEFEI----------------QEYIDETL-T NVGHAYTRLF------RTPLGEKIVIYTSRPGLVVGKKGENIKKLTTTLKKRFGLENPQL EIA-EIENPNTNPTIV----------AERISSSLERFGIQRFKAIAHRTMADVNDAGAQG VEITISGK-V------------PS-------------SRARTWRFH-------------- ----TGHIEKCGNMATEKMGAAYSTAYLKSGAVG-------------------------- ----------ITVRIT---------------PPDL----------KLPDAL--------- ------------------------T-I------------I-EE----------------- ------------------------------------------------------------ ----------QEVK-----------DEKEGAK---------------------------- ---------------------------EPAAK---------------------RAEKDAE ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -MKFPAQFEE-PLRKDLIIRAVLALRS-KRQPYGAMTRAGIEASAKLSRRRR-A---YRG AYNKGISRIPRKTMTARGSSMNWVGALAPHARGGIRAHPPK-----AAKQWEQKINDKER KKAIRSALGATINKDLVQERGHKAP--D---KYPFVLEETFEKLAKSKEVMKKF---QEL GLKEELARCTP--R-IQSGKTRMRGRKTKTARGPLLV-V-S-QACP-------------- -----LSKAARTIPGVDVRTVTRLNAEVLAPGTHPGRLTIYTKPA---LEIMEKKGLFL- ------------------------------------------------------------ ---------------------------------------------M--------KTIRYR RKREGKTDYKNRRRLL-TSAKARLVVRKTNKHLTLQIVHYDPKGDKIQTSASTREL-EKY GW----KGATSNIAAAYLTGILLAKKA----GPVDVIADIGLQTSIKGGRLYAALHGSKQ AGIKISL--GEKTVPA------KERMAGQHAKVDAAV----------------------- --------VEGVKKKI------E-----ESQWKK-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKGV-AARVVKGLNHGSVVLACDNSGA RKLRIISFKG--AKTRKDRKPRGGVGDYIMASVREGKPDMRKQ---VVAAVIVRQRKSYR RADGTRVMFEDNAAAVLKDEL-GNPKGTVIKGPIAKEAAD-RWPMLAKIARMVI------ ------------------------------------------------------------ ---------------------------------MKTHGRTFTGTVLSAKMANTVTVEWTR VRFVTKYERYEKRRTRVKAHNPKEID--AKKGDIVRIMETKPISKTKHFIVIEK------ ----------LG---------------------------------------------QAK LFETKQELMEEGRHRDQPKEEKEEPKEERA------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MATKEFMFRGKSLE--------------------ELKQLDIDSFIKLL TSRERRSLTRGT------RHEQKKLLEAIQKQKK------------TLKTQ-ARDMV--- ------IVPQM----------------------------VGKTISVHSG--------KTW Q-----------PILIEADMLGHR----------------------------LGE----- ----------FALTR-NKVAHSA------------------------------------- -------------PGVGA-TR-------------------------------SSAALSVR ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLASIDIDKINQTCTYIQDIADKTGVHMRGPVPLPTKKIKVT TRKCPCGDGK-------ATWERYEMRIHKRLIDL-GLDERALRLVMKVPVPDGLNIEIEM IE---------------------------------------------------------- -MNA--------------------------------HTKGKA------------------ -----------------------R-STRVKEGMTVKVVRG--QHK--GKQAKVSEVNTKK STVYLEGIEATRRDGQ-KAPIP----------IHTSNLFVEAQK---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MAKLRKFSAYQTV--------------- -E-RPYTRHSKYK---TKNFVRSR-PNNRIVRFVMGDR----KKQFKQ-KLQLICDQRM- -QMRDNAIEAARQTCNRLL-ELELLPP-NYRFMIHVFPHHILRENPLSA-GAGADRMSTG MAHSFGKNIGIAAQVKK-GKVILSVQF---S-EKE-DIVKTALKRAAAKL--PCKCLI-- ---------------------R-------------------------------------- ------------------------------------------------------------ -------------------------------MLN-DTLASGLSIVQQNDRQGKRACRVQP ASKTIKCVLDVLNKEGYVGQAEEAAAAR-GGQLKVHL----------------------L GTINKIGVIKPRFAVKISDFEKFEK--------------------RYLPAHGMGVLIVST SQGIMTHVAAKEKKIGGRLLAYCY------------------------------------ --------------------------GVTGNYELP-----DLSIK--GEKGEVKRSF--- P-Q----VQIKL-EGNT-LKLA---IK-GDK---RKQKKLLNTCVSHAQNMVQGVQEP-F VYKLKICASHFPMQVALQ---GST--LQ-VKNFVGEKHPREMNVP--EGVKIEIKDT--- ----DITVESPDKELAGRVAGRIELLTRLTG---KDRRI----------FQDGIYITEKA ------------------------------------------------------------ --------------------------------------MQYWPRKRSSKSHARLRTNAP- K--------EAKPSFMAGFKVGMTHVAFIPAKGNS--K--GQQVVWPVTVVEFPPLRVAG ISLYKKD--AYGKHKAGHVVDG------DK-----------FYQRI-------------- ----QHT---K--------K-KGS-----------------------LEGIK-------- ---LE--GIDSLRLIVQTQP-----NLTGIGRKKPDVFEMALGGTP-E---EQFAFAKEK FGK-DITLQDVLQEGMLVDAHAVTKGKGFQGSVKRFGVAIRHH--KSEKSRRS--PGAI- GPW--RGGKM-TKVPMAGQMGYHTRTERNKLLVQIGS---EPE--KINPKGGFQGYGMVK NPFALFRGSLPGADKRLIKFTLTKGK-----------EEAP-TLSHVSQ----------- ------------------------------------------------------------ ----MAEEKKAEPEK------------------------------------KVEQPKAEA KK------------AETK-EKQVDA--------------NEE------------------ -----------AHAVSTPNVSFKQSTEIASNI--RGKKVEEAQKILQAAIDEKAPLAFTK YCK-GLGHKP-----G-----MGP-GRYAPKASKAMLVVLNSAAANAENKGM---SNLVV STITTSK-----------VGG-----NRATRHGYDGKR-ARIEVRV-------KQQ---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRLITQA-------------RGKGGPTYRARSFRNV- GKTKM----PSQFQGV----GK----VMNLVNCPGHSAPLMEVEYDNGIS-CLVQAPKGI RIGDKVEAG--------------GTE---TNKGSILTLQDIPEGTSIYNIESQPGDGGKF CRTSGLSARITGK-TG--E-YALVLLPSKKERKFPLNCRACIGVIAGGGRTEKPILKAGS AHHARRARNKKYPHIRAAAQNAVDHPLG-NKRTARH---A-K----QKPVNRFAPPGAKV GKISPKRTG-------KRK----------------------------------------- --------------------------------------------------------MKNV RLEKVTLNFGAGKEQAKLEKGEAIIKAI-TGK-APLRCITE--K--RIPSWGVRPGLPIG AKLTLRKQ-EA-LALLKRLLTAKENKLKPSYFDQNGNISFGIPEYIDIPDTKYDPKIGVL GLQVCVTLERP-GYRIKRRRLRQTKVGKKHTVTKEEAQKFMTESFKVQV-EEEA------ --- >GCA_011332615 ------M-PHKL--RKIRK-FRGSR--TQGYGRIGQHR-DSGSKGNR-K-VGRHKHLWSK IVT-----TDPG--------------------------Y-F--G-------KN-GFTSPQ SIHR--VE--NT-----I-NLHKLDQ----LATGAS------------------------ IN--LTELG--YTKLL----GTGKITKAL-TVEV---PAASKSAAQKIQEAGG--KII-- LPEAEV----------------------E----ASEE----------------------- ---------------------------------------------------------MSI V--------------------KRFITESIKRTEI----------------DEFLQKKL-E RAGYGGVNLS------KTPLGTHVVIYAMRPGLVIGRGGETIKELAASLEQNFKVSNPQI SVS-EIEVPEFNAHVV----------ANRVASALER--GVHFRRAGFWALNQVMEAGALG CEIVISGK-L------------TT-------------ERARFEKFK-------------- ----AGHYPIVGEPALRAMKTAEVHVQLKPGMIG-------------------------- ----------VRVKIM---------------PPDA----------YFPDKV--------- ------------------------T-I---------------MEPKPE-EETPIVV---- ------------------------------------------------------------ ----------TQEP---------------------------------------------- ----------------------TPAPASAS--VTP------------EQAP-TVEANKV- -TEEP------------------------------------------------------- ---------KPAEAPKTEEKPAEE------------------------------------ ----KQ------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------M-AQKTAEIFDLQGKSTG KITLPEVFQT-PLRPDVIKRAVLAIQSSRLQPQGRDPMAGKKTTAESRGTGS-------- ----ATARVPR-QKG------GGKAAFAPSTVKGRQPHPPR-----AEKIIVKNIPKKEA KLALSSAIAATAEKDVVAARGHKVD--AV-VGLPLVVDNALEGLTKAKDVEAAF---SSL GFTAELTRVKES-RNIRAGKGKHRGRKMKQAVGPLIV-V-A-DAKS-------------- -----LINAASNLPGVEVTTVANLNTEMLAPGTHPGRLTVWTNGA---IEKLSA--LYGE KA---------------------------------------------------------- ---------------------------------------------MAKSSN---YRVQLR RRRAGKTDYQARKAMV-ISGRPRLVARPSIKNVTAQIIIAKPQGDQVLAAANSRELIKKY GW----KAATGNVPAAYLTGLLCGLKAKAA-GVNEAILDIGMVIPTKGSKVFAVLNGVLD AGVEVPH--GEEKMVF------E-RNRGEHIANYAQELGV-DSDEYKAKFSKFIA--AQV APEKLTEHYSKTKAAI------------VGSFKGAVVAPEPETKPKKAPTKEKAAPPKEK AAPAKEKAPAPPKAPETAPAPVKEKAPVAPAAKEAPKAKAPEAKAVEAKAAPAKEEAPVE KAPEAPKAEKAVKAKVPAKEAKAKAAPKEKAPKEKTPAKEKAAKEE----KAAPAKEKAP AKKATKKGEKKA---------------------MLTH-GQKISRGLLAGSEMRCTDNTGA RVLRLIQAMG--YKGRLRRYPSATVGDKVTVSVRQGSPDMRKK---IFQAVIVRQRKAFR RIDGVWVQFEDNAAVIITPE--GEMKGSEIRGPVAREAAE-RWPRIASASSIIV------ ----------------------------MS---MT-FKQ-PKKT-----------C---- -D----DPNCPF------------------HGTLAVRGRVLEGIVHTAKMDKTVIVDREF TQFSSKFVRYERRHGHIPSHNPPCID--VKEGDRVKIAECRPLSKTVSFVVVEK------ ----------VG---------------------------------------------EER ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MPKEFSYRGHSLE--------------------SLSGMSMDEFINLL PSRQRRSLQRGL------TAEQRILLEKLRTAKE-----NNQG--A-IKTH-VRDLI--- ------ILPEM----------------------------VGAKISVHNG--------KEF V-----------AIDIKPEMIGHY----------------------------LGE----- ----------FAITN-KPVRHGT------------------------------------- -------------PGIGA-SR-------------------------------SSMYVPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------VRKARIRLTSTDYAKLEEVCGELRSIAQKTGVKMNGPVPLPTKRLRVP VLKGPSGEGT-------ATWDRWEMRIHKRLIDI-DSEERVMRRIMRIRVPEEVHVTIEL I----------------------------------------------------------- -MQN--------------VVKNPGKQRKMLFN-APAHKRHKM-MAAPLSDELAAQR---- ---------------------GAK-TLPVRKGDTVRIMRG--DSK--GFEGKVSRVDLKE YRIYMEGLTREKVDGT-NIFLA----------IHPSKVQIRNLNLD-------------- ---------DKY-RK-----------------------------------DLLGRKTAP- ----EKKQKPKATVKKAVK------AEKAPAKSKAAIEEEKEIEKAFEEAPKVEETQKVA AKPAVKKAPAKKAVAKETAAK------ETEEK------------ASEE------------ -------------GGE--------------------MHAKNYRHV--------------- -KNRAYTR---------KEYAHGF-PPPKIVKFTMGDT----KAQFDV-EGQLIATERA- -QIRHCALEAARVATNRVL--MDKLIN-DYYMNVHPYPHIILRENKMIF-GAHADRLQQG MRRSFGAAIGTAAKVEV-GQPIMTVRV---K-AGQDAVAKESLKRGSAKL--PIACKI-- ---------------------V-----ISKIQLPPSQPET-----------AEQEMEKLE Q----------------------------------------------------------- ---------------------------------M-DTLTNGLVTIINNETRNKRECVISP ASKLLGRVLRIMQLNGYIGEFEFIDDGR-QGKFKVQL----------------------L GRINKCGPVKPRFAVKSTEYEDWEK--------------------KFLPSRDVGIMVVST SKGVIAHKDAEEKNIGGRLLAFVY------------------------------------ MRLPEV------------SRTIQVPDDVTVNVVGK-----TINVK--GAKGTLTRDFS-Y A-T----VAIEG-QGKN-VRIS---AK-WPR---KKEAALVGTIYSHINNMITGVTKG-Y SYKMKIVFSHFPITVKLQ---GKS--VL-IENFTGERRPRKVDIL--GDVKVKIEAE--- ----DIIIQGANLEEVSQTAANIEQSTKVRR---KDPRV----------FLDGIYTYERN EGMA-------------------------------------------------------- ------------------MG-------HRKTHAPKHGSLAYLPRHRAKKPSARIRYW-P- K-IKSD---SPRLLGFTSYKAGMTYVFTIEDRKRSPNF--GKEVMRAATILETPPILVCG IRTYRKT--PYG-LE---NITEAWMKEPPAA-----L-----NRLL-------------- ----VLP---ENF------NTEAM-----------------------LQKIQDN------ ---SQ--TTDVVRVITATQP-----TQTSLSKKKPDTCEIQIGGGTIQ---QQLDYAKQL LGK-TVTPEEVFKEGQYIDIAGVTVGKGFQGPVKRWHVTKLQH--KGRKTKRG--IATL- GPWN-PHHLM-YSIPRAGQTGYHQRIEFNKRILKIGK---DGK--EVTVKGGFIRYGEVN GPYILISGSIPGTEKRQIRLRVPAR---P-P-TETP-EAAP-QVTYISVESPQGK----- ------------------------------------------------------------ ----MPKWGYSIVQ-------------------------------------ESLNSEKTA I----------------------------------------------------------- -----------ASGRELK-VSHKAAREVTKAI--RGMDLAKAKDFLRDVIAKKKPVPYTR FTK-KLGHKG-----GMQ--KRFV-GRYPIKTADAVLKVLQAAQANAENKGL-DVDRLRI VHSAANQGMKLKRYTP-------RAHGR--ASPKYDIT-THVEIVL-------EEKATSG ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------EQ--------- ------------------------------------------------------------ ---------------------MGKRIRVQR-------------RGRGGQNFRASTHKRV- APAKYP-AIAPKESFEAELVGV----IVDLVHDPGRGSPLSLIEFEDGSS-IYSITPEGV FTGQEIKYGG-------------KAP---AEIGNIIPLGKMPEGTLVCDLELRPGDGGKM ARSSGAYATVVGH-TP--Q-GTMIRLPSGRTRYVDDYCLATVGVISAAGRIEKPFLKAGE KFHLMKAKGHKYPRTSGRKMVPAVHPYG-SSK-RSA---R-R----TTTTSHGAPPGQKV GLIAARGPG-------QKKKRAIRG----------------------------------- -----MSEEAMIKNW---------------QEH----------------------PMLQP RIEKVVVNLNVGKSGEPLEKANKVLQEI-TGR-TPVKKKAK--S--TIRDFGIREGESIA VVVTLRKQ-EA-IDFLKKVFPVVDNKLARRAFDVRGNFSFGLKEHIEIPGVKYDPEIGIF GMDICVTVNRP-GQRIKIRKRQSKPIGPKHVLTPEESIAFIKQTLGVEI-V--------- --- >Bin683_genes -----MV-TFKR--KKVTK-YRGSK--THGGGSMKKRR-GAGNRGGRGM-AGTGKRADQK K---------QTILKKY-------------GNA-----Y-F--G-------KK-GFKLK- --KK--KV--NS-----I-NLYELDK----LIEN-----KQI-KK---------EKDTYI IN--LTKLK--YTKLL----GSGKISNKY-EITI---NSYSKKAKEKIEKLGG--KIN-- V---------------------------SI------------------------------ ----------------------------------------------------------MI E--------------------RKTINKKIKELLI----------------QEYMDKEL-P KACYSRIDLK------KTPLGEKVIVHTAKPGLVVGRKGANIDKMTKALKFKFKMENPQV EIA-ELENPNLDPRSI----------AETIVSSFERFGPKRFKSIGYRELQKIMDSGATG AEIVISGRGV------------PS-------------KRSKTWHFS-------------- ----EGHLKKSGDISENHMKRAIVVASLKSGAIG-------------------------- ----------IKVNIL---------------TPDI----------RLPDEI--------- ------------------------I-F------------K-TKKVDE--IKVEKKKVPK- ------------------------------------------------------------ --------EEPKVE-----------ETKKEE----------------------------- -------------------------------------------------------KKKIK ------------------------------------------------------------ ----------------KVKK---------------------------------------- -----DGNKK-------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------MIIQDLEGKKVK ERKLPEQFSE-EYHPNLIKRAVLTLQSNKRQPYGAKPKAGLRASARISKRRH-D---YRG CYGHGISRVPRKVTWRRGTQFGWVGAIVSSAVGGRKAHPPK-----AEKNWNKKINIKEK RKAIRSAISATLNLDLIKERNHIIP--K---NYPFIIESKIEDLQKTKEVKLTL---EKL GLKDELKRIEV--KKVRAGKGKSRGRKYKKKTGPLIV-V-S-SNCK-------------- -----LTKAGTNIPGIQIIKVENLNAELLAPGTQAGRLTLFTDKA---IERLEKEKLFIN N-------------------------------PIKKEVKKKVKK---------------- ---------------------------------------------MRKN-----YTVKFK RKRKLKTNYKKRLEQI-KSKKTRLVIRKYSKTILAQLINYETKGDKTLLLIKSQEL-KKL GW----KYNIKNIPAAYLTGLLLGTKAKKL-KINEAITDLGLQRLTKNSVIYATLNGAID SGLKIPH--DKSILLP------KEKINGSDLAKNAKNIKNKN------QFLSYNK--NNI KIEDIKKNFDEVKSKI------------LKNG---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAL-EAKIVKSLPVGSRISVCDNSGA KIIKIFSVKR--CKTVKGRYPAAGVGDLVNASIIKGKPGMKSQ---VVQAVIVRQKKEYK RTDGTRIKFEGNAAVVLKDDK-GNPKGTIFKGPIAKEAAQ-RWPGISKVAKIIV---MVK -----------------------------------------KQE-----------C---- -D----DKKCFI------------------HGNVKLRGRILKGTIIKKDISRTATIEFPR FYYLAKYERYEKRRTRLKVHNPKCIN--AKIGDIVEIKETRPLSKTKNFTITKI------ ----------LK------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVLK-YKFKGKTIE--------------------ELKKMDLNEFAELL PSKQRRSIKRGF------TEPQKIFLKKIDKAIEG-----SQK--KPVKTH-CRNMI--- ------ILPKM----------------------------VGLTIYIHQG--------KEF V-----------PVKIEPEALGLR----------------------------LGG----- ----------LTLTR-KRIQHSA------------------------------------- -------------PGVGA-TK-------------------------------SSTAVSAR ------------------------------------------------------------ ----------------------------------------------------???????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- -MKI---FSKA-----WIRSKKPKKQRKYRYN-APSHIKHKF-LGAHLSKELIKKY---- ---------------------NKR-SIPVRKDDKVKIMRG--KYK--GKEGKVARVLVKK SKIYIENIQITKLDGT-KIFVP----------ITPSNVRVTELNLT-------------- ---------DKK-RK-----------------------------------KILERKNG-- ------------------------------------------------------------ ------------------------------------------------------------ ----------------???????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????----------------- -----------------------------M-SLN-DPLSNVLSQINNCEKIGRNECVVKP ISKTILNILKIMKDEKYIGDYKAEDDKK-GGFIKINL----------------------L GKINKCNVIKPRLAFKKEYMDKFEK--------------------RFLPAKDFGIIIVST NKGLLTHYKAKEIKTGGRLIAYIY------------------------------------ MVLKDI------------QEKISIPEGIKINIEDG-----ILKIK--GPTGENERKLL-N P-K----VKISK-KENF-IILE---SK-KPT---KKEKKIVNTFKAHINNLMKGVTKK-F IYKLKICSGHFPINVSLD---KNI--IT-IKNFFGEKKPRKAKIL--KGVETKIKGD--- ----EITLEGTNKEEVGQTAGNIEQSTRRCG---FDRRI----------YQDGCWITEKS GKKVR------------------------------------------------------- --------------------------MSSNKSKPRSGSLQFWPRKRAKKAYARVKSW-N- HNLK-----DNKLLGFIGYKVGMTHILFTQQNSN-KKN--NESTFSPITIIECPPIKPLC LRFYKQT--PYG-LN---SISQLFSKKLNKE-----L-----SKKI-------------- ----KLP---K--------KSKDK-----------------------I------------ ---PE--EFDEIRLLVYTQP-----KLTSLPKKKPEIVEMAISKKD-------LEYAKSL LEKDSITIKDVFNENQHVDIRAITKGKGNQGPVKRFGISLKGH--KSEKGRRS--PGSL- GNWV---ART-WRVAHAGQMGYHQRTEHNKLILKISE---KPE--EINPKAGFKQYGLVK NSYLLIKGSIPGPRKRTIVLTNPMR---D-K------KTHSTEINFIKK----------- ------------------------------------------------------------ -------MEYKIN----------------------------------------------- ------------------------------------------------------------ -------------AKDLG-ISTKVSVEICNLL--RNKQVKNAQKILERVIKKKEAVPYKR YKK-EIPHRP-----G----KMAT-GRYPIKASQTILKLLKGGLASAQNQGL-TG-DLII SHMSAHKAGNQWHF------------GR--ARRRRMKK-THLKIIL-------KEEKKND ------------------------------------------------------------ --------------------------------RKKDDK---------------------- ------------------------------------------------------------ ------------------QKN--------------------------------------- ---------------------MGKRIITQR-------------RGRGTSTYKAPSHRYK- HIITY--------PKSEVKTGQ----IIDLVNDTARSAPLAIIRLDDNSK-ITIPAPLNV RQGDQI---N-------------FTE---IKPGHILKLKDIPEGTQIYNIEKLPNSNGTF CRAAGTTAKVLAK-TA--S-HISIQLPSKKKKKFHPECRATIGIIAATGRLEKPILKAGK RHHMMKAKGKLYPKTSGVAMNAVDHPFG-SGRGRHI---G-K----PKTAPKNAPPGRNV GLIRAKRTG-------KKK----------------------------------------- ------MKN---------------------PNN----------------------PMKEI SIEKITLNLGVGEAGDKLEKAVRLLQKI-TGQ-KPVKTKTF--K--RIPTWSIRPKLEIA TKVTVRKN-TE--ELLKRLFSALNNNLSENKFDTNGNFSFGVEEYINIPDVEYDQEIGII GLDVAVTLQRP-GFRIKRRRLQKSKINKSHKIKKEEAIKFIKDKFKITI---EE------ --- >Bin458_genes ---------MKKT---NIH-LVELI-------------------------EGLKEKAKKE N---------TNAWLK------------------------I----------AD-ALSKPT RKRK------------VV-NISKINHY----------------SK---------ENDVVL VP----------GKVL----SAGNLNHKV-TVVA---YQFSQQAKEKINK-NG--ATM-T ITEFIEK------------------------SPKGQ-MRVLG------------------ ----------------------------------------------------------MG KK--------------SIQVVNIVVSTSLEHAIP----------------LEKMAATL-S NTEYNPEQFPGLVIRIKDPKTSALIFSS---GKVVCTGARSMDKVEESIK---------- ----------------------------KIIKSLEKI-NIKIKIKPEIKIQNIVASGTVG MALNLNTLAMKLENTEYEPEQFPGLVYKLPQ------AKATFLLFS-------------- ----NGKVVCTGTKSEKEVHEAL------------------------------------- ------------------------------------------------DKL--------- --------------------------I--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --ENLKKVVK-------------------------------------------------- ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????MERFADEIKKYLKKGLKVKDIF LSKPPSPEMGDYSFPCFSVAKQLKKDPNAIAQELCKKM-----------NIGSWIKKIEI RGPYLNFFVNEKKLASYVLDKIQKEKNEYGSKNIG-------KGKKALVEHTSINPNASP HVGRARNAMIGDFIARLLKFQGYKPETHYLVNDVGKQIAILVLGSKDRKKISFDDLLKLY MKASKKAENKGF------EQNSLELLKKLEQGDKK------------VRKM-FRNIVETC IEGQKKIFGEMGIKYDYFDFESEYLWKKETAKVLKKLRKTGDVFTDEDGRNVLNQ--KDF K-----------LAMKTPVLVLTRADGTSLYVLRDLAYHIEKAKKAKTNIVVLGEDHKLY FQQLKAALSLLKIEA-PRVVHYSFILLTEGKMSTRKGNLVLLEDFMKEAVAKAKKEIVKR HGKVKNIERLAKIIGYGA-TKF------SVLKVSPEKNVVFNWDSALNFEGESSPYVQYA HARICSILKKYRKRLEKKVDFSLLKKEEETALIKKLAEFPDIINKSTAELRPHHLAGYLV ELSQRFNEFYHNCNILKEEEQLKKARLLLADSVRQVLKNGLNILGIEAPDEM-------- ------------MQKARIKLVSVDIEKVNEVCDFIREIAEKTGVEMRGPIPLPTKKLKLT TRKSPCGNGK-------ATWERYEMRVHKKLIDL-GIDERALRLIMRVPIPEGLHIEIEM IDV-----------------------------------------------------MDIF ALRT--TANREDQVMDFVTSNAKKKKLEVYSVIRPHGMRGYIFLEADSRTDAEQAAFNVP YARGILPNKINYSEIEHMLEQVKR-EVNIKKNDIAEIISG--PFK--REKCKITRIDKTK EEVVVELLEA-------AVPIP--------ITVKIDAVKVIRRESE-------------- ---------EED-KEETGEE----------------------------------TETP-- ------------------------------------------------------------ --------EETL------------------------------------------------ --------------------------------MAKLKKFVAYRRI--------------- -E-RAYTRISKFR---KKSFIRAT-PQSKVVRFEMGDA----RKKFDY-RLNLISKQSI- -QIRHNAIESARQSSNRVL-EKNLGKT-GYHLKIRIYPHHILRENPLAV-GAGADRMSTG MKKSFGKPIGSAAQVRK-DQIIVTLSL---N-KQHTKTGIEALKRISHKL--PCSYII-- ---------------------Q-----AVEKKEKH------------------------- -------------------------------------------????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??? >GCA_016933055 -----MT-MKFK--KHVNK-YRGKR--THGFGRQQGRR-KTGRKHGHGLTTGWQKGQKSY MVK-----QKSLGFPTQKYGKKI-----KRSPW-----K-F--G-------KH-GFSRPQ TQVR--IYRKNF-----I-NIGSLNA----KLDGWVK-EDLA-QK---------SGDTYS VD--LDNLN--IQKIL----AKGSITKKV-QVRV---RSISEYAKEEIEKAGG--KVF-- LIES-------------------------------------------------------- ---------------------------------------------------------MPL K--------------------RAFVQRGIQLMQI----------------DEYLAELL-D NSGYAGVELQ-----KRYPLGYQITIKTARPGLVIGRKGVRIREIGEKLTELFGLENPQI DVE-AVENPELNSQIM----------AEAIAFGIRK--GQNYRRTAYNIMRRIIRAGARG VEVKISGK-S------------TS-------------QRARTQIFR-------------- ----AGIISKCGAPAIEGVDKGVAQVVLKSGTIG-------------------------- ----------IVVKIM---------------PLDY----------QLPDEI-IL------ -----------------KDP----E-LKAR----------LEKYRKKQ-ALEEE------ ------------------------------------------------------------ ----------VEGG-----------DPLIDK----------------------------- ---------------------------DSKKVV-------------------LDAGDEE- -DEED---------------------------------FFDDVEEDIED------I---- ---------EVEEAIEEEEETIEE------------------------------------ --IQPKEEPPQKDKKKRTRR---------------------------------------- --------------------------------NRTT------KKKNE------------- --------DKEE---------------------------------MANINVYGLDGEVKQ SIRSPTFFSM-NPRKDIISRVVSAIETSEKQPQGRDPLAGTRNTAKSWGSGY-------- ----AAARIPR-KKG-SGYPGARNAAFIPRTVGGRLAWPPT-----SEKKIPKSINRKEK KLGLLNAIVASSMKDVVVQRGHKIE--KV-PSIPLVVDDKIQTIKTTSEILKVF---NKL GLSDDIERVKSS-VKIRSGKGKRRGRKYKKRKSLLVV-V-K-DNFG-------------- -----IFQATRNIPGVDIVEVSKLNCRDLAPGALPGRLTLWSHSA---FKQLNNF----- ------------------------------------------------------------ ---------------------------------------------MMAGPR---YRVSMR RRREGKTNYQSRLKLV-LSGKPRLVVRASIHSIIVQVVEARLKGDKVLVSAHSSQL-VKY GW----KYNSGNIPSAYLVGYLCGLRAKDK-KIKECVLDLGILV--HKHRVYAAFKGFLD GGIEVPH--GDSVFKKLN---LESRINGTHIKDYAILIQKKDKKKYEREFSAYLK--NGL DPSKITEDFDKIKNS-------------ITKKL--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGKKR--KIGK----KGSIFRKKITRGLPVGAQVRIADNSGA KIVEIISVLH--LKTRLNRLPSAAVGDAVVVSVKKGTPEMRKK---IMRAVIVRQKQLIH RVDGTRIMFEDNAAVIISPD--GEPKGSDIRGPIAREAAE-LYPRVASVASQII---MS- ------------------------NTSKIG---IPGVTE-PSKK-----------C---- -D----DPHCPF------------------HGNLKTHGRIFTGTVIKNRMTKAITVQIDY NKFNDKYQRYERRNTKTSVHLPPCID--VVPGDVVRFMQCRKISKTISSVVIQK------ ----------LQ------------------------------------------------ ------------------------------------------------------------ ------------------MSTD-------------------------------------- ------------------------------------------------------------ -----------EFERKKFTYRGKTLK--------------------ELQKMSMDEFIQLV PARMRRSLKRGL------PKRHKKVIEKLRKAHRAA-RAGKEL--I-VRTH-CRDLP--- ------IFPEF----------------------------IGLTIGVYNG--------KDF I-----------PVKVTPEHIGHY----------------------------LGQ----- ----------FAPTTPKPVTHGS------------------------------------- -------------PGIGA-TK-------------------------------SSQYVPLK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARVRLMSANLSDLQKVSDEIAQVVEKTQDKMYGPIRLPTKRLRLT TRKSPCGEGT-------NTWEHYEMRIHKRIIDV-LAQDRSMLLIMKIKIPESVIVEIEL ME---------------------------------------------------------- -MKV--------------KSKKPKKQRLALHT-IKQHQTSKL-FMVRLDEPLQEEW---- ---------------------GIK-RMPLRKDDEVRVIKN--EMV--DVEGKVLSLNRRT RTIQIEECTLEKKSGA-TYYIP----------ISPSNVILTKFGGKK------------- --------MDSW-RQ-----------------------------------KIIDRKQK-- ---------------------------------------------------------LEI EVDAKKKISEKKGGK--------------------------------------------- --------------------------------MA-RRPWSCYKQI--------------- -KRPAYQKKRSRSH--RKEYVRGG-PDSVLRMYDTGNRKKP-LEEWDL-SLGIKILKDV- -QLSHRTLEAMRTSLNRNL-QKQLGRT-GFLIRVRPHPWQMIRENKMMA-FAGADRLQSG MRNSFGRVIGRAARVHA-DQTIVEVYC---N-FANKNIVIKSLKTAAYKI--GAKNRL-- ---------------------V-----VLRMKDPALETK--------------------- --IGLP----------------------------IALEE--------------------- -------------------------------MLH-DPLADCFSNIKNAEHAGKRYVIVRP ASKTIGICLRILQANGYIGEFEFIDDGR-TGKFRLEL----------------------L GRINKCGVIKPRQPVKVTRFEFMEK--------------------RFLPSVNFGLLIIST SKGVMTHTEAKRRNLGGRLLAYAY------------------------------------ -MVKSFKS----------EIVVEIPEDITFLIEGK-----KITIE--GKKGKIVKDFS-H M-K---RVDIKY-TDKK-VILS---SF-FPR---KSTEAKMGTLRSVITNAIEGVSKG-Y TYKMKIAYSHFPITVDTD---GKK--IL-VKNFIGERSPRITYKAGSHPIEVKSTKE--- ----DVVITGIDKEEVGQTAANIQKICRIRQ---KDKRI----------FQDGIYLYEKH LGDEIFWKLKV------------------------------------------------- ------------------MG-------HRKQNAPRHGSLRYMPRKRANHIKGRVRNW-L- E-VEDK---NPLFLGFAGFKSGMTHIAYIEDQKTNPFF--GKELMKPVTIIETPPLVLFG VKVYEKS--EYG-LK---CKGELLNTKLNKE-----L-----ARKI-------------- ----SLPN-PESY------DFDQK-----------------------KQELEKI------ ---ID--SNSIIRGLFHTQP-----YKASVPRIKPDIIEIMVSGGSTPD--KQFKFALEH LGK-DIRVRDVFSEGELIDAIGVSKGKGFQGPVKKFGIKLLPR--KTRGTKRG--VGCI- GPWH-PSRVM-YTVPRAGQMGFHQRTEYNKRIVKISE---TGD--EINPKGGFLHYGLVK GDFIAVLGSVPGPKKRLIRIRKSMR---P-K-KNFE-VVAP-TITYISRQTQQGK----- ------------------------------------------------------------ ----MPNFGYSIT---------------------------------------GLDKDKTA I----------------------------------------------------------- -----------ASGRDIK-VSPKNTREVTNTI--KGMYLEQAKRFLEEVIFMRQPVPFKR HNK-KVGHRK-----GLKQYKWAS-GRYPEKSARIVYEVLSNAEANAEYKGL-DTERCRI IHAAVMKGRSIKRYIE-------RAHGR--STPYFDTL-VHIEIVL-------LEE---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRILVQR-------------RGRGTPNFQSPTHKRR- GQVKYRYFPPTDTDEK---TAT----VKDLLHDPGRGAPVALIQYEDGKK-ELYLPPEGI KVGDTIVIGN-------------NSE---IKVGNVLILKNIPEGTYIYNIEGQKDDGGKF VRGSGTYAVMLTK-TP--T-HANIRLPSGKIKRVPLTSRCTIGVVAGGGRTIKPFVKAGN KFMYQSTRHGVWPRTSGVAMNASSHPFG-GGGHKSP---H-K----PTTISRNAPPGRKV GLIAARRTG-------NKK----------------------------------------- ----MAKKKQVAEYEQ------------DWKSN----------------------PFRQP KIEKIVVNICVGQGGEELNKAKRILELL-TKS-KSVTVQAK--K--NVKEWGIRKGQSIA VKSTLRGD-KA-HQFLKRVLFIYDNRILRTAFDNFGNFSIGVDEHIKLPDTKYIPELGIT GFDVSVRLTRP-GYRVKIRRKQRSKIPRHHYVNRYEAMEFMKQLFKVEV-VDVMEERFY- --- >Bin502_genes -----MV-VRKT--KKVNK-YRAHT--THGGGHRKKRR-GAGSRGGRGN-AGSGKRAGHK K------------------------------RQ-----PLA--G-------RH-GFRPR- --RTIETI--KS-----I-NVSFFTAV---KVEKLVV-EGNA-TK---------EGNTYV ID--LAKLG--VQKLL----GTGKTSVAL-KLTV---AQASEAAIEKVKAAGG------- -----------------------------NVSTSGKTEV-----------------AEKA ESA--------MA----------NILKEITKVLP-EGTVAEATFEGANIIIYTKDKDYFL DN----KGTI-----------RAAVKEFKKRIEL---RPDPSLCMTMEKAEKEIKKLVPK EAGVQEFFFD--------PQRSVVIIHADKPGLVIGKQGEALKEIAEKT-----CWVAKV KRM-----PPIQSKLIESVRSVLYEDAVARKKFLSKTGHRIYDGWLRGKKHEWVRLSCLG ASRQVGRTCFLLQTP-------ESRI--VIDCGIDPGE-EGTETYPYLDAPEFNISEIDA VVVTHSHLDHSGLIP----------YLFKFGYEGPVYCTYPTRDVMALLQLDMIKIQRSK GQEPIYKSEEVRKMVLHTICLDYDEVTDI--TPDVRL-TMYNAGHILGSSI--------- ----------VHFNIG-NGLH---N-FAYTGDLKYGRTNVLEPGNTQF-PRIETLMIEA- -----------------------TYGGKDNF----------------------------- ------A-NEKEADEYMVNVI----KKTFERGGKVLMPVLGSGRAQEVMVIVERLIREKK VPMANVFIDGMLWDITAIHTAYPEYLNRTLREEIFHKGNNPFLSPIFKRVGSHKERQEII HDGTPALI----------LATSGMMSGGASV------EYFKQLAGNKNN----SII---- ----FSCYQPPGSLGHRIRAGASE---------------V-------------------- ---MFGDGGQKDIVSINMEVHKIE-I-----------TAHSDRRQLM------------- ---------------NYVKRCNP---------QPRKVIVVHGEASRCLDLASSIHKAYRI ETVAPKNLEVIRLK--------------------------------MKVAILNKDNQNKG EVDFPSQFSE-SYRPDLIKRAVLALQSAARQAYGTNPEAGQRHSSTVSKRRR-N---YRG CYGFGISRVNRKILSRKGTRMFWVGATSPQTRGGRRSHAPK-----AEKIFEQKINKKEN QKAIRSAMAASIDKVIVAARGHQLP--E---TYPFVLSSDFETLTKTKEVESAL---EKL GLKAELERSSV--KKVRAGVGKLRGRKYRRKKGPLVV-V-S-GKCD-------------- -----LEKAAKNLPGVDVVYVNALNAEVLAPGAQPGRITLYTEKA---LEIIGKENLFQ- ------------------------------------------------------------ -----------------------------------------??????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????????????????????????????????????????????MKPKLKM- ------------AQKARIKLASTEINKINKVSSDIKEITDKTGVTFRGPIPLPTKKLKVT TRKSPDGEGK-------ASWERYEMRIHKRLIDV-SADERTLRLIMRVPIPEGLNIEIEM VDN----METE---------------------------------------------THLF GVRT--AANREDQVVDYLISKLERKPGGILAVIRPHGMRGYIFIEAISKGDAESGLMGVP YARGVLAHEIPYPEIEHMLEQVKV-EMNIHKNDIVEIISG--PFK--RENAKVMRINKQK EEIVVELLES-------AVPIP--------ITVKMDAVKVVRREDD-------------- ---------SDD-E---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MGKLRKFAAYQNL--------------- -E-RPYTRVSKYT---NKNYVRGGFPQMKVIKFDMGDP----SREFDT-VIQLKSTRAM- -NIRSNALESSRMTSNRLL-EKTIGKK-EYHLRIKVYPHHVLRENALAS-GAGADRLSTG MKKSYGKSIGCAARVKE-GQVLVEVQV---N-KANTKIGKEAMSRAAKKF--PCSCKI-- ---------------------N-----VVGLN---------------------------- -------------------------------------------????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????------------------------------------------------ ---------------------------MPKPHNPRRGSMQFWPRKRSRHSLVRVRSW-A- P-EN-----QAKPLGFIGYKAGMTHLMVTDNRPKSLSK--GDKISMPVSIVECPPMTVVG VAFYNKS-------K---KVSSILAEKFDKS-----V-----SRTL-------------- ----TLP---K--------KPGKK-----------------------IDDIQ-------- -------DFDNIRIMVHSNP-----SKTGIGTKRPKLLEMALGGS-KE---EQVAYAKEH LGK-DISVADVFAAGNQVDVHGVTKGKGFQGTVKRYGVPIKQH--KGEKNKRG--IGNL- GAWT-PKRVD-YRVAQPGKMGYHLRTEYNKHIIKIGE---DGK--EVTRIGGLQKYGIVK NTFVLVKGSVAGSKKRALVLTKAIR---S-N-YKIT-KDAP-EVAFISI----------- ---------------------------------------------------????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????????????????????????-- ---------------------MGKRLIQQR-------------RGRGTHTYKAPSFRYK- GAVKY-----PSYDT----AGT----IVDLIHCQGHSTPLMEVSYLTGEK-GLAFAPQGI KVGDMISVGP-------------DNE---IKPGNVLPLRDIPEGTLVHNVELRPGDGGKL VRTSGTSAKVVAK-SE--K-GIRIVLPSKKEKLFLPNCRAAIGVLSGSGRTDKPFLKAGT KFHKMKAKNKLWPIVCGISMNAVDHPFG-GKCSHIK---G-------------------- -------------------------------------------------??????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??? >Bin300_genes --------MVKRTGPQTLE-LKELI-------------------------HDLKVLGGKN D---------IKLWKR------------------------V----------AK-DLEKST RSRR------------KV-NLYRIDKH----------------TR---------DNEIAL VP----------GKVL----SVGELTKKI-TVSA---YDFSESAREKINK-IG--KAI-S IRKLMED----------------------NPNPKGKRIRIIG------------------ -----??????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????---------------------------------MKLVDLQGKKVK EVTLPKQFSE-PYHPNLIKKAVWTIQSNKRQPYGAKPEAGLRASSDLSKRRR-K---YRG AYGRGKSRTPRKVMWRRGTQFGYVGATAPGTRGGRKAHPPK-----AEKSFKKKMNIKER RKAIRSALAATFNLDLIKKRNHQIP--K---EFPFIIENKIESLEKTKEVKNTL---KKL GFEKELKRCEE--KKVRAGKGKSRGRKYKRKTGVLLV-V-S-KKCK-------------- -----LEISAINLPGIEIVDIKNINTELLAPGTHAGRLTLYTEAS---INKLEKDKLFQK ------------------------------------------------------------ -----------------------------------------??????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????????????????????????????????????????????-------- ------------MQKARIKLASNNIDQLNEIITSIQDIAKKTKVKLQGPIPLPSKNLKIT TRKTPCGRGK-------ATWDRFEMRIHKRLIDL-KVDERTLRLIMKVPIPESINISIEL LE-----M------------------------------------------------SEIY TLKT--TANREEQVLDFVVNNIKKKELKVYSVFHPHGMRGYIFIEAETKDDAQRSYQGVP YAKGLLRVPVNYQEVEHMLEQAKA-HVNIQNKDIVEIISG--PFK--GEKARVTRIDEQK EEIVLELLES-------AVPIP--------ITVKLDSVKVIRRDNE-------------- ---------DD------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------???????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????------------------------------------------------ ---------------------------MPQRSKPRAGTLQFWPRKKSKKIYPNIKSW-K- KT-K-----ENKLLGFIGYKVGMTHLHYLQQNPN-IKK--NIETVSAVTIIECPPLKPFS LRFYKKI--PYG-SQ---VITEVLSKNFNKE-----L-----SRKI-------------- ----IMP---K--------KQKEE-----------------------I------------ ---PK--EFDYLKLLVYTQP-----KLTGIGKKKPEIIEIGIS-GD-------LEFAKSL LNQKEIKIQDVLKENQYVDIHAITKGKGTQGPVKRFGVSLKQH--KSEKGTRR--VGSL- GNWT---AKT-WRVAHAGQTGFFKRTEYNKLIFKISN-----D--KINPKRGFHKYGNTK NDYVILKGSIAGPRKRVIVMTEPLR---K-R------RTFPLNITSIKK----------- ---------------------------------------------------????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??? >GCA_002686855 -----MT-VNKR--KKVVK-YRGSK--THGCGSMKKRR-GAGNRGGKGA-AGSGKRADTK K---------PSIW-K---------------RK-----Y-F--G-------KH-GFKSK- SAKS---I--NT-----V-NIEYLEE----NIHKLIS-KEQA-SK---------ENNFFS VD--LGQLR--FNKLL----GSGRVLNKY-KIKV---SYASKKAIEKIKSNGG--EVI-- L---------------------------T-----IKKENNR------------------- ----------------------------------------------------------MI E--------------------RKFVAQKIKEHQI----------------EEFIVNSL-K NVGHSRTKMI------KTPLGEKIIIYASRPGLIVGRKGQNIKELTENLKRKFKLENPQI EIS-EVENISLDANIV----------AERIMGALERFGAEKFKAVGHKTMQNVMDAGALG VEIIVSGK-I------------PS-------------SRAKSWRFY-------------- ----QGYLKKCGDIALTGVNKAQTQAKLKTGTVG-------------------------- ----------IKVSIM---------------PPDT----------KLPDKV--------- ------------------------E-L------------I-DTKQEE--I---------- ------------------------------------------------------------ ----------EEVK-----------ESKEEDK---------------------------- ---------------------------TEKKD-----------------------EKQAE KD---------------------------------------------------------- -----------------EKKSKTK------------------------------------ -----KPAKKED------E----------------------------------------- --------------------------------------------KNE------------- S---------------------------------------------MKLSIFETSKSKTG EISLPRQFNE-EVRPDLIKRAVLALQSNRKQPYGASPQAGKRSSAMLSKRRR-A---YRG CYGFGISRTPRKVLSRRGRRLFWVGAFAPNTVGGRRAHPPK-----AEKILSKKINKKER RKAIRSAISATVISDLVKSRGHILP--E---NYPLVLGKNFEDFSKTKEVLATL---KNF GFEKELERTNK--KSIRAGKGKARGRKYKTKKGPLIV-V-S-KENN-------------- -----LTKAASNIPGIEVVNVKDLNAELLAPGAIPGRLTLWTKAA---IELLEKEKLFLK ------------------------------------------------------------ ---------------------------------------------MKRSNI---YNIQFR RKRKGLTDYRRRLRIL-SSKKPRLVVRKSLKNIQASIVVYDKKGDIVKVSFHSKNL-KKF DW----TYNTGNIPAAYLVGFLLGKKAKDT-NLGEVVLDIGSQKSVKGSRVYAVLAGALD AGLKIPY--SKDILPS------KERITGMHINHYAQALKKDES-LFKKQFSGYLK--NSI DLGNISKKFEDVKNNI------------SKNQGK-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAI-KANVTKAIPVGSEVETCDNSGA KVLKIFTVVG--SKTTKGKMSAAGVSDLVMASVRRGRPDMRKQ---VVYAIIVRQKKEYR RADGTRIKFEDNAAVVLKDEK-GNPKGTTFKGAVAKEVTD-RWSAIAKIASVVV------ -----------------------MEMKNIG---LD-VKK-PKGK-----------C---- -E----DSNCPF------------------HGSLKCRGRTFTGTIVSGKMQKTVTMEWEW KNYIRKYERYEKRRGRIKAHNPACIN--AKEGDIVKIMECRPLSKSKNFVVVEI------ ----------LG-KEKGF---AQRMEAEEESKVK-------------KEGKVEQ---EQA EKE---------------------EKVEKVTA---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFTYKGKKLD--------------------ELKNLSLTELAELL PARQRRSLKRGL------TEQQKILLRKLRKDKQ------------NIETH-CRDMV--- ------TLPEM----------------------------VGKIIKVHNG--------KEF V-----------QVAIIEEMIGHY----------------------------LGE----- ----------FAMTR-NRVQHSA------------------------------------- -------------PGIGA-TR-------------------------------SSAALSVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLASIDINKINEVCSYINDIAEKTGVEMRGPIPMPTKKLRVT TRKSPDGEGS-------ATWERYEMRIHKRLIDL-GLDERALRLVMRVPIPEGLNIEIEM IE---------------------------------------------------------- -MRT--KFSTS-----WKNSIQPRKQRKYRYN-APLHIKQKF-VNVHLSTELRKKH---- ---------------------NKR-NIGLRKGDKVKVMRG--QFK--NKEGKVDQVNLKK TQVYVEGIEITKKDGT-KTRYP----------LHPSNLMIAELNMD-------------- ---------DKM-RQ-----------------------------------KSLERK---- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MARIRKFVSYRRI--------------- -E-RPYTRISKYK---EKSFVRAN-PNIKVVAFETGTP----QKKFKY-TLKLISKDDL- -QIRDNALESAKQTSNRLL-EKSIGTS-AYHLKIKPYPHHILRENPIAA-GAGADRFSTG MQKSFGKPIGAAAQVRR-GQTVFQVSV---N-KANLELAKTALTRASKKL--PCSYTI-- ---------------------Q-----MTENK---------------------------- ------------------------------------------------------------ -----------------------------M-SMN-DPLANALSLILNDEKIGKNGSSIKP SSKIIKNVLEIMKDNRYIGDFEEIENGR-GNIIKVNL----------------------L GNINKCGVVKPRYSVKKDQYEKFEK--------------------RYLLARGMGILIVST PLGIISHDEAKKKNIGGRLLAYCY-----------MEKK--------------------E SKRKEL------------SEEIKLLDKVNAQLNGG-----ILTLK--GEKGEVKRDFS-D K-K----TTIEQ-KDNT-IIIK---AH-KFS---KVRKKLIKAYAVHVRNMIKGVQEA-H KYVLKICSGHFPMNVAVG---NNE--LV-VKNFLGEKVPRTLKLK--EGATVKVEGD--- ----QIIVESASKEIAGQVSADIEQLTRRTG---YDSRI----------FQDGIWIINKD GKEIK------------------------------------------------------- ---------------------------MPQKRTPRKGSLQFWPRKRSKRAFARVRFW-P- V-SK-----EPKPLGFAGYKVGMTHLIINDNRKTSTTK--NMDIFCPATIIECPPLKTAS IRFYKNT--ING-SK---LISETFAEKLDKE-----L-----ARRI-------------- ----ILP---K--------K-SKK-----------------------ESKEI-------- -------NFDFLHLLVYTQP-----KLTKIGKKKPELFEIALGGNK-E---EQLKYAQEK LGK-EINIDEIFKEGQQIDIHAVTKAKGVQGPVKRFGISLKSH--KGEKSRRN--PGSL- GGWIAQGHIM-WRQAKAGKMGYHTRTEHNKWLLKIN----KTN--ELQKKGGFEHYGIIK NPCIILKGSIIGTKKRLIRLNQATR---P-D-KKIP-QDPP-TIQYTNLKSG-------- ------------------------------------------------------------ ----------------------------------------------------------MA R----------------------------------------------------------- -----------ASGKSIP-VSFKHSIEICNFI--RGKNVNYAKNVLNDVIKEKRAIPFKR FSD-DVGHKK-----K-----MAA-GRYPKKASKEILDIINLVEANAQFKGL-NTSNLII TSISPNKASSVTRF------------GR--KRGRKAKR-TNIEVFV-------QEKV--- ----------TEKKSSVKKESK-------------------EEKKEVEAQDKKGKKM--- -----------EKTENIKDKPKGSKE--------TEEKQ--------------------- --------------------------------------------------EVKTVKKEEN ------------------KAQK-------------------------------------- ---------------------MGKNLIQQA-------------RGKGSPRYRAPSFRYK- GQSKY-----ARQEKE-ILTGK----IIDLVHCPGHSSPLAQIEYDNGSV-ILMQAPEGI RIGDPVQMGD-------------KIE---VKKGNIMPLKSMPEGTAIYNIEASPGDGGKF VRTSGGFAKIVAK-MQ--N-GVVVQLPSSKTKRFLPDCRATIGIIAGSGRKEKPFLKAGT RHYAMKAKNKLYPSVSGTSMNSVDHPFG-GSSSAHK---G-R----PTQAARNAPPGRKV GKIAPKRTG-------RKKR---------------------------------------- -------------------------------MN----------------------PMKLI SIEKVTLNIGAGKDQTKLEKGIKLINNI-AGH-PPVKTFTR--K--RIQEWGLRPGLPIG CKLTLRKK-EA-LELLKRLFESKDNTLQPGNFDNEGNISFGIPEYIDIPGVKYEPEIGIM GLQVCVTLKRS-GFRIKHRAWKKKVIPRKHRISQNEAMDFIKKTFNLMV--GE------- --- >GCA_014727915 ------M-AHGS--RKTNR-LRGSR--THGYGNAQKHR-GAGSRGGRGM-SGSKKQKWAR ISK-----NMKG--------------------------Y-F--G-------KK-GFKRHK TTVE--DV--KT-----M-NVGYLSD----HIGRLVS-EGAA-TE---------SKGAYT ID--LAASG--IGKLL----GAGKVESKL-NITV---NSCSPRAREKIEAAGG--TVE-- VQKAED----------------------EF--LEAQSGEEAEDS---------ESGE--- ---------------------------------------------------------MAI E--------------------RHFIQEGVIRSEI----------------ESFLRNEL-N RAGYSGITIQ------KTPLTTRVVLYVEKPPIVIGKKGSRINSLTNMLKEKFGVDNPSI DVQ-KIEKPTLDPNII----------ARRIAVALER--GMNRRRIAYKAVRAVMSSKARG VEIILSGK-IV----------GKG-------------GRSRNEKYS-------------- ----EGYMKKAGD-SLKLVRIGSTQAYLKAGVIG-------------------------- ----------VTVKIV---------------PPDT----------KFPDHI--------- ---------NVLKGVK-EE-----E-IEGE--D-------TKKKAKKK-TKKKAKK---- ------------------------------------------------------------ ---------AKKTA-----------EKKDDP----------------------------- -------------------------------------------------------GEDK- -EETG------------------------------------------------------- --------A------SKADDGSEK------------------------------------ ----AEKE--ESNA---------------------------------------------- ------------------------------------------------------------ -----------------------------------------------MVNVYLLDGKVKG KVDLPKVFQA-PHRPDLIQKAVVAEQANVRQPYGVSSLAGLKTSADYFGSRR---RTYRQ TINRGMTRLPR-VKS-GGG-GLGQVRRVPQSTGGRRAHPPR------GRDYTRKLNRKEY MIALHSAIASTASRKLVEGRGHTAD---V-KEVPIVVEDKIEGLKHTKDVLKMF---KSL GLDGELAS--------------------KKKRKMLIV-V-G-EDKG-------------- -----IFNAASNIEGVDVATVNDLDVELLAPGTQAGRLTVWSEAA---VKRIGEDGTA-- ------------------------------------------------------------ ---------------------------------------------MATGAT---YSVRYR RKRQQKTDYKRRLNLL-KSETTRFVVRPTNKNTIAQLIEYSEDGDKVVAQANSGEL-KKM GW----AHSTSNTPAAYLSGLLCGVRGREK-GVEKAVLDTGLYPMIRGSRIYAALKGLID SGVESGA--DEVIFPA------EDRIRGKVIAAYVE------------------------ RSKNIEADFDKVKASI------------LKSSK--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------MPKNLPLGKAV-SASVTRALPAGARLHCADNTGA KEIEIITVRG--YKGVRSRMPKGGVGDMVVATVKKGRPDIRKQ---VVHAVIVRQKQPYK RVNGSRICFEDNAAIIVSEE--GMPKGTEIKGPVAREAAE-RWGKIGSIASIVV------ ------------------------------------------ME-----------C---- -S----DRNCPV------------------HGNLATRGMILEGEVVSDKMQDTVVVKRER LVKVKKYDRYMKSTSRIPAHNPPCIN--AKQGDKVTIMECRKLSKTVSFVVVGK------ ----------AG-----------------------------------SEPAAES-PEKKT KKKTKR------------------KKAKKASKKGVNDG---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFKYRGYKIE--------------------ELQKMSHDEVLELL PSRARRSLKRGL------TEQQQKLLKKVRKARETG-QKGA------VRTH-CRDMV--- ------ILPEM----------------------------VGVKFAVYTG--------KEF S-----------EFEAKTEMIGHY----------------------------LSE----- ----------FTLSR-RPVKHSA------------------------------------- -------------PGVGA-TR-------------------------------SSLFVPIK ------------------------------------------------------------ ------------------------------------------------------------ ------------MEKARIILIGKEVDQLEDVCTQIVDVTKKTGTKYSGPVPLPTKKMRVT CRKSPDGEGT-------GTWERWSMHIHKRIIDV-SANERSLRQIMRIQVPDGVHIEIEL TK---------------------------------------------------------- -------MKMK-----RPSSKQARKQRKWVGE-APLHMRHRL-VSAALSKDLKDKY---- ---------------------KKN-SMPLRKGDTVKVMRG--SVK--GHVGEVMKVDLKT YKVYVQGVTAKKSDGT-DVERA----------LEPSNLMITELHEE-------------- ---------DKE-RR-----------------------------------DALSRNME-- -----AE----------------------------------------------------- ------------------------------------------------------------ --------------------------------MASLRPAKCYRWD--------------- -S-PAYTRVSNNP---SDSYITGI-PGSKIIHYDMGNP----TGDFNT-KVEIVYNDKC- -QVRHNALEATRILVQKRL-EKLVGVT-NYHFKVNVFPHHVMRENVQAS-GAGADRVSEG MRRSYGKPIGRAARLKP-GQALFTVRFN--KTDTRLKTIKKALRLASNKL--PGDKSV-- ---------------------I-----VSELKK--------------------------- ------------------------------------------------------------ -------------------------------MRH-DPLNDAISTIKNAERTGKSECMLKP ATKLLVSVLHIFQENGYIGEYEVEGNRR-GGSVRVKL----------------------I RHINDCGVIKPRFPVKNQDFIQWEK--------------------RYLPSRGFGLLVVTT PQGVMSHEEAKDKGIGGRLIAYAY------------------------------MSNTDK KHHGEL------------E--VGLVEGVEVDAKGR-----TITVK--GPKGELTRKFR-- ----EDFISFKP-HDGR-IRIQ---AK-SKRLPLRKQMAIMGTIAGHIRNMMEGVTDG-F TYKLRVVYSHFPMKAMVQ---GSE--FV-IDNFLGEKHPRRTKIL--DGVSVDVKGN--- ----EVVVSGIDKESVGQTAANIEQLTRIKN---LDVRI----------FQDGIYIIEKA GKPVL------------------------------------------------------- ---------------------------MAKIHKPRAGSRAYRPLKRAKSEKPRIHSW-P- A-GKG----DSKVLGFTGYKAGMTHCIAVDESKDSPTS--GSEVFVPVTILETPPMKVVG VRVYRKA--YGG-EQ---TFTDIWCETPDES-----V-----KRRA-------------- ----STP---KKK-----GNPDKK-----------------------IAEAEKK------ ---SG--EISDVRLVAHTQP-----ILTHSPKKTPDIMELAL-SGDVP---EKLAYAKEV LGR-EITINDAFSESEFVDVTSVTKGKGFQGVVKRYGVKRQPR--KASGKRRH--LGTG- GSWT-PTKKL-WVEPQPGQMGYHTRTEHNKLILKIGE---DGG--EVSPAGGFLRYGPVK SSYVMVYGSVPGPSKRVVRLTQPRR---S-H-KEV----SL-TLKSVDLSSKQGA----- ------------------------------------------------------------ -----MDLKYSVK---------------------------------------P--EEGAV K----------------------------------------------------------- -----------AMGRDMN-VSFKDLVVVADAI--RGKKVSKAIEYMESVVELKNPVPYRK HNK-GVGHRK-----GKE---VKV-GKYPQKAARHVLAVLRNLAANAEYKGY-DTEKLKL THVQAQKGLARLRRKP-------K--GR--WALWETQY-SHIQMIA-------KEA---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRHITQR-------------RGRGNPRYRSPSHRYK- GSVKYP----RI-DYKGRISGQ----VIEFDHDPGRTAPVAKVLLEDFTT-VQLIAPETV TVGQTIEFGS-------------GAS---VSNGNVLPLKNISPGTGVFNLEVKPGDGGKI VRSSGSFALIVSH-DKSTG-LTQVKLPSKKTKFINSDSLATVGRVGGGGRKDKPMLHAGQ MYYRKKAKGKLWPVVCGRAMNAVDHKHG-GGRHPHV---G-R----PTTVSRNAPPGRKV GHIAAKRTG-------KKKRG--------------------------------------- -----------------------------MMAN----------------------VMEQP RIEKVVINIGVGESGERLGKAEKLLEKL-TSR-KPTRTISK--H--KNPTWNVRKGEPIG CKVTLRGG-DA-VEAIKRTLYAKDNMLRPGNFDVSGNVSYGIQEYIDIQGLKYDPEIGIF GMNVNINLERP-GYRIGRRKQRQVKVPDHARVTRDEAIKYMEKEFGVKI-EEEE------ --- >GCA_016212525 -----MS-KRKE--GQKKG-YLGHR--SHGRGNVKNRR-GSGNRGGRGM-AGIDKHKWSW ---------AMKY-----------------DKN-----H-F--D-------KH-GFVRPQ GTSV--DV--DT-----I-NLYYINQ----RA----M-LNQL-EK---------KNGKLY FE--F------DGKIL----AVGNLSVPV-VIRA---SAWSKGVEAKVKTAGG--ELV-- KL--------------------------GKAAAKPAA----------------------- --------------------------------------------------------MLYQ E---------------------KLIEEPFSKFQV----------------MKFLEKEL-D RAGLASVDIQ------RTPLVTRITLEVTNPARIIGKKGRLINELTETIKREFKIENPQI SVV-EVRNPFLEPRMV----------AKKAAKYIEM--GKKVRAVLHFMLREIIRSGALG AEIVASGK-IG----------AKG-------------AKAKTLRVG-------------- ----AGHIPKSGEPS-RLVKVAHLHANTQSGVIG-------------------------- ----------VLVRLT---------------PPGT----------VFPDK---------- ------------------------K-TDKV---------VLPKVI--------------- ------------------------------------------------------------ -------------------------ETAQDVE---------------------------- ---------------------------RRPETGGF-----------------DHRRRRA- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MKATVYSLEGKVMK QIDLPEVFHS-SDRSDLVKRAVLSEESELYQPKGSYRFAGLETSARYRGRKE-D---YGT VKNKGIPHLPHEVLP-GGQ--IGKVKRVPHAVKGRRAHPPK-----ITKKIVELINKKEH LKALSCALSMSCNSKLVSKR---MKT-ELTIALPLVLENGFEKLSKTRDVLKVL---TAL KLDHFVEMAK------KTG-----------KKAPLIV-V---SDGL-------------- -----VTKAAANLAGVNVVRAADLKVKDLAPGTHAGRLTIFSENA---LPEIARRFVA-- ------------------------------------------------------------ ---------------------------------------------MTRAKG-PAFTVAFR RRRDGKTNFAKRLALV-KSGLPRMVVRRSNKNLLVQFVTFDPKGDKTLLSFDGFHLAKNH KWI-----SKRNVWTAYLVGLAAGKMAQKK-GVKDFVFDMGLYTPSKGSVVFAALKGAVD SGLT-------------STSMSEEKVPTEKLSN--------------------------- PPEALKASFEDVKKKL------------SSG----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKGL-TSKISKTLTTGTMMTCSDNSGA KVVYVIGAMR--YKGTRSKYPKVGIGDIVIASVKKGKPDMVKK---VVKALIIRQKKEFR RANGMRVCFEDNAAILINDD--YLPVGTEIKGVVAREIAE-RFPKVAAISAGVV---MAE K------------------------------------------------------C---- -D----DSKCFM------------------HGDVKVRGERLFGKVVSAKSKKTVVVERSA VKFFPKYAKWARGRSRIAAHNPSCLS--AKVGDMVHLAECRKLSKTKAWTVVEI------ -----D-------------------------------------------------SSEGA SI---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------MKKDVWKGIDEE--------------------GITSLSMDDFMKKL TSRNRRTMLRL-----NVNPRLKQFVEEVRATKKANPK-------KAIKTH-IRDAV--- ------ILPEW----------------------------FGLTFMVHNG--------KEF K-----------RVDITLDKIGRR----------------------------LGE----- ----------YAHTV-GRVLHSG------------------------------------- -------------PGVGA-TR-------------------------------GSKFVPLK ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKVRITLIGEDAAALDNVVNQIKDLAKMLSMKFAGPVRLPRKKLEIF CRRTPCGDGT-------DTYEHWEKRVSKRLVDV-EGD--DIKQILRIKVPTSVLVKIAL NN---------------------------------------------------------- -MKSD-------------------TERKHFYS-EKLHKRKDR-LNVHLSKDLRSKLK--- --------------------TKKR-ALLVHKNDRVKILRG--PET--GKEVKVVRVNINA RKVYLEGVVVKNSKGK-EVLIP----------IEPSNLLLVGLESTPERKEIFREDAFIV AKKEVKKEDDKKDEKKTV----------------------------VSEPKTSEKTQP-- ---VSQKSAHQDTT---------------------------------------------A QEARAHAAQDKQHKNY-------------------------------------------- --------------------------------MA-LRPGRAVRSP--------------- TK-RPWTRFSRSKP--RKSFIKAM-PHKDLHQFKMGAQ----KADFDM-VVNLTSEEPV- -ILRDNAIESARQTANKYL-EENVAGA--YSFVVRVYPHHIIRENKMIA-GAGADRLQKG MRQAFGRPTDCAARLHK-GTELFTIHSY----KSNLPHVMVALERARRKL--SGTYEI-- ---------------------Q-----TQ------------------------------- ------------------------------------------------------------ --------------------------------MS-DHLADALNILKTHELAGLSTCNLK- ASKVVGEILRVLAENKYLKSYEMVEDGR-GGYYQVVL----------------------D GRINDCGVIKPRAPVKRAHWAKKEQ--------------------QYIPGFGVGLLIVTT PNGIMTNSEADKQHVGGRLLAYVY------------------------------------ --------------------MISVPDGVQVKVDGR-----TVWAK--GPMGEVQKILP-- -----KEVAIKL-DGKN-ISVS------------SLDKSLVGTSEAIVTNVLFGVSSG-Y KKSFKLLHAHFPISVEVK---GKD--IV-IKNFLGEKQPRKTVVV--GNTKVDAKGQ--- ----NVTLSGPDKEALGQTLANLRTAMRIKD---KDGRV----------FQDGIYEVASE ------------------------------------------------------------ ---------------------------MTDIRRPRRGSMAHRPRKRAYSQNAHV-FW-P- N-SS-----EKRVLGFAGYKVGMTHVSYVDD-TDSPTK--GQEVVSSATVIEVPPMAVYG VRCYHGGN----------SLGDILVT--DEK----TLKEVGIHKKHAP------------ ----------K--------PVDES------------------------------------ -------KVTDVRLLVFTVP-----AKTGIGKKHIEKMELGCGGKDAK---EKLAHGKSL LGK-ELKFSEVFKLGEFVDVVSISRGKGWQGAVKRFGIAIQRR--KATGKRRH--VGTL- GQWH-PAYVL-YTVPQAGQTGYHQRTELNKRILKLGQ---KP--EDINPKGGFRGYGIVR NDYVLVKGSVPGPAKRLVKLRTAVR-------AGSP-IKEP-NVGYVAK----------- ------------------------------------------------------------ ------MKGYSL------------------------------------------DLENGA K----------------------------------------------------------- -----------ARVEGVN-ASYKDLAAVCGVI--RNKRATWAMTFLERASLGEIPVLFRK HNK-NLGHRR-----E----LGGRMGRYPEKAAGIVLKVLKSALANATVKGMDVNSNLTV AHASANKKMTYPR----------MAPKG--RTARSNLETARVEIIL-------LSEAPVP ----------------------------------------K-SAATSKKESPAS------ -------------------KSAPVNSV-----PSAHKKSEP------------------- -------------------------------VKVPQKSAEK--------KEAK---K--- ------------------------------------------------------------ ---------------------MGKRLKQQK-------------RGSGSPRYLAPSHRYK- TDLTY--RRYDDVEKTGVLSGT----VVSIVDDPARTGPLIEVKYENNER-GFLLAPEGI AVGAKIQVGA-------------QAT---LSLGSVLPLYRIPDGAYIYNLERNPGDGGKM VKASGSYANVVAK-DG--N-IVYIKLPSKKTIELSNECRVQLGVIAGGGRLEKPMLKAGN QYYKKTAQNRLWPVPRGVHQSPYNHPHG-GKQH-HV---G-K----PTTVARSTPPGGKV GHIAARSTG-------RRKGKKAIEAARSK------------------------------ ----MTDN-----------------------------------------------PMRKI LIDKVTVNIGVGSPGDRLENAKTLLSKL-SGAGTPVETKAR--K--RDPVFKLRKGLPIG AKITLRGA-PA-KTFLEKALAAKRRTLKESNFDRRGNFAFGVHEYIDFPGAKYDPTIGMF GFDICVTLRRP-GNSVALRRLSPSKIGAKHLITPHEAREFIKNSFNVKF-E--------- --- >GCA_011776705 ------------------------M-------------------------STREKRG--- -------------------------------------------------------FTPPK RREY------------TIMNIGRINLF----------------LKEGSLTPPKEEGKWVI HPKELD-----VDKVL----GAGRVDEEI-KLVVSPKTKVSKKAEEKIKDAGG--SIS-R IE----------------------------GKSASSQ----------------------- -----------------------------------------------------------M Q------KK------GIIPYSQRILQDKTLEMQI----------------ERFVKSEIPQ PAGIADVKVRP----GKGGLGKSIWVFCENPAIAIGKDGWRVKKLEKNLRERFDLDKAKV SVK-EMGNPDLNAEIV----------ANRTAAAIER--GVHVRRAGWSTVNRVMRAGALG VSVRISGK-V------------YS-------------TYSQSYRFA-------------- ----DGKLIHSGHIAKKYVEEGKASALVKTGKIG-------------------------- ----------VKVKIAK--------------PPHL------LSSSGQEERL--------- -------------SIK--------E-L-----------GIKNKASVRG------------ ------------------------------------------------------------ --------ELERIK---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------TQSKKLAEKTIKE------------------------------------ ----TRRGKK-------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----SFFTN-RVRLDLIKRAVLSLQSKRRQPYGQSPWGNKKWVVEPRGK---------- --GYDTSRVSRTRGG------MGQARVIPQAVGGRSVRSPS-----SDKKIVEGINKKEK LKALKSALAATADPNLVLLXXXQVP------EVPLILENKFEEIERTSAVLKVL---EQV GMGPDLKRAREG-QTIRSGKGKRRGRKYEKKKSLLLV-V-SSKESK-------------- -----VIRAARNLQGVDVVPYEYLSVENLAPGAHPGRLTLFTEKA---LKLLQEK----- ---------------------------------IENQLKKW------------------- -----------------------------------------??????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????----MPKR---------TSQAWSRRKGTPGVQTESVLDCADNSGA RKLKMIAAIG--YHGRKRRQPYASLGDQIVVTVKKGKPELRHQ---IVRAIIVRQKMPYK RANGEWIQFEDNAAVMIDSE--GEPKGTEIRGAVAKEAAK-KWPAVGKIARIIV------ ------------------------MSKLSG---L--FPK-PEKV-----------C---- -N----DKKCPF------------------HGNVNVRGKKIKAKVVSNRMQNTVVVEREY IRKDAKYGRFKVESSTISAHNPPCID--AKPGDDVIIMETRPLSKTVRFTVVQK------ ----------NP------------------------------------------------ ------------------------------------------------------------ ------------------MNDEEEW----------------------------------- ------------------------------------------------------------ -----------PPEWKKFTYKGYSLK--------------------ELQEMTLEELSEVV PARLRRSLRRGL------TPEQRRFLERLNKEEG------------PVRTH-VRDMP--- ------ILPNM----------------------------VGRKIMVHNG--------NDF H-----------PVEVIPGMIGHM----------------------------LGE----- ----------FAYTN-KEVDHSR------------------------------------- -------------PGMGA-TR-------------------------------SSKFLSTK K----------------------------------------------------------- ----------------------------------------------------------MS RFKRKRGRRKRREMKITFKITGLESGEIEQFGSRIVSSLEKRGVNVSGIIRLPNKRLTIP TRRSPSGEGT-------ESWDFYEMVIHRRLLRM-ELSPNQIPLLTAFRIPSDTYTEIKF L----------------------------------------------------------- -MLR------------RSVSSKPKKVRKSHYN-KPLHKRNKK-MTAPLTEEAKVEY---- ---------------------GVK-RAPIRRGDKVIVEKG--EFR--DHIGEVTRVDLKN YRIFLKGATIEKASGQ-EIHIP----------IRPWNVSIMELKMD-------------- ---------EV--RK-----------------------------------QTLTRKKE-- -----PEEIEEALFEEEPR----------------------------------------D EXGNINRKRRRKAF---------------------------------------------- --------------------------------MPTKRPARSYREA---------P----- -N-KPYTR---------HEYVKSV-PESQLRILTYGKG----DRVYEY-RISLISGQKG- -MILSRCLEACRTAVNRYL-ERNLKES-PYFWRFRTFPHHIVRERRFLG-VAGADRIQSG MRLSFGNPVDRGAIIHL-NQPILELWV---N-SENLVQAKEAVRRGRAKI--GLETRVE- ---------------------------IEEVNAKPQES---------------------- ------------------------------------------------------------ -------------------------------MLL-DPLANALSTIKDCDTVGKDMAYIKP VNRLIKETLKILKEKGYIKEAMYIENNK-GGIYRVKL----------------------T GNIHDLKAIKPRFPVKNDEIEKWEQ--------------------RYLPSYALGTLILTT SQGVMTHERVKEKGIGGKLIAYVY-----------MKFQ---------------FLTGKD ALLQAIKK----DSPTVGYEEIDIPKGVEVNLNGK-----IVKIT--GKEGEFIKDFR-H V-RL---IEILR-ENDK-LFVAR-----RIRR--RKDKAPIRTVASKIRTAIEGVQRR-Y VAHHKVVFSHFPVRVYTQ---GNQ--II-LENFYGRRQETRVPIVG-ENTEVEVEMEAGS NVPSDVFIKGPDLDAVTQTSSRLVEICKLRGKRRKDVRV----------FQDGIWLWRME REKK-------------------------------------------------------- ---------------------------MPKKHSPRRGSLGYR-RKRAKSESPTVSNW-P- D-AE-----NPQLLGFPVYKCGMVTLYVEKRIRDRYREVFGKEATYAATVTEAPPIRILA VRVYRET--PYG-KK---TFKEVWTPHFSTFER-KYL-----ERRV-------------- ----NLP---KNY---TEENTQKE-----------------------INDLSGE------ ---VD--GSDEVRVIARTMP-----ELIGIGRKKPKLLEIGVGGTG-K---AAFEYGTTI LGE-KVSVTDVFEKDELVDCIGVTKGEGFQGVVKRFGVRLLPP--KTKKGIRK--VAAM- GAWR-PARTS-WRVPQAGQTGFHKRTDHNKQILEILG--GDEV-GNFNPNGGWKHYGLLR QPSVILKGSVQGTQKRVLSLRKAIR---P-T-----------ETEEVQLKSAWYSR---- -----------------------------ELLKAF------------------------- ----MGRKGYSFQ-----------------------------------VDAVP-DKTRLA L----------------------------------------------------------- -----------AKGKDLP-VSMKDAREICNAIMEQGMMLKEAIQYLNAVLEEEAAVPFKR FHK-HAGHRK-----GLDLWKWDA-GRFPKKAAKAVKGVLNNALNNARFKGL-DEEKLRI LLIAAHPGEKIRQRPD-------RR-GRGGYRGTMTKRGTNIECSV-------IEIEEEV ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --MKW-----------------------------------------------HILAAEGV HSGKKIEMGK-------------GAD---LSLGNAKILREIPEGIYVYNIERDPMDGGQI ARSSGTYAIVGEH-DEERG-VTKLELPGKRRIEVNSDSMAQIGVAAGTNRQELPMLKAGN VAHKYKARPLKWPRTRAAAMNPVDHPFG-GGRG-----VG-R----GKTSSRNAPPGAKV GSIAAKRSG-------KKKK---------------------------------------- ----MQEYP-------------------EKYPN----------------------PHLVP TIEKVVVHCCVGEAGGELENAEKILKDL-TGR-QPALLRAK--K--TVQGFNIHKGQPIG WKITLRGN-EA-FSFLKRVLEVYDKTVWKGNIDERGNLSFGIEEHQEIPGAEYDPELGII GFDVNIALARP-GYRVKKRKERAQSIPKRHKVEKEDAVLFFKILGTVREGRRQKTFV--- --- >GCA_007117475 -----MV-SNKR--SKNTR-LRGSH--THGYGGKKKHR-GAGSRGGRGM-AGTGKRADTN K---------PSISAN---------------TK-----Y-F--G-------VH-GFTPV- -NRK--LV--QT-----I-NLNTLQS----RIEGLVA-QKVA-EK---------KGDTYV VD--LTKTA--YGKLL----GSGSITIPV-TVTV---NTASARAIEKVQAAKG--SVV-- V---------------------------VDTVSDSTESEA-------------------- ----------------------------------------------------------MI E--------------------RKIVNEKMTEFLV----------------EEFLDEQF-N KVGHSHTEIQ------KTPVGEKIIIHAARPGLIVGARGANIKKLTRLLKSKFKLENPQV DII-EVKNVAINADLV----------AENIAYQFERFGSQRFKAIGYRAMDDAMRGGAMG IEILISGK-I------------PS-------------TRARTWRFY-------------- ----TGYLKKSGDLAVSGVLTAYSQAKLKTGVIG-------------------------- ----------IQVRIM---------------PGDL----------ILPDKL--------- ------------------------E-L------------I-R-EMAD--VTA-QVSPDNI IDAASNKPRGRDNRKGGNTSRPNTGKAATQS----------------------------- -------TDSQKAK-----------DEPAPAAPLN------------------------- ----------------------LKDALKAKKE----------------GATKAAAKKVAE PKAKTA------------------------------------------------------ ------------PVEAKA-ETTPE------------------------------------ ---VT--ATETVEATPKTE----------------------------------------- ------------------------------------------EKKPA------------- AE---------------------------------------------------------- ------------------------------------------------------------ ----------------------------------------------------------ER RKAIRSALSATIDKSLVAARGHKVP--D---SYPFVVADDFAALAKTKDAFTAL---IAA GFEMELERSSA--KTARAGKGKMRGRRYKSRTGPLFV-V-A-DKCE-------------- -----LTKAARNIPGVDVVLVSELNAELLAPGAVAGRATLFTKAA---IEKLTTDKLFM- ------------------------------------------------------------ ---------------------------------------------MADTRK---YNVPFR RKRTGKTDFKQRLSLL-KSRKPRLVVRKSLQGVVTQLVEYTPDGDKVITTVRTSDL-KKY GL----TVLNGNVPTAYLTGLLLGKKALAK-GVSEAIVDAGLQKLTDQSRIFAVVKGAVD AGLDVHS--SDSHFPS------EERLTGVHIEKFAQAVAD-NADVYNRQFSGYIA--AKI DPKAISKTFATVKAKI------------VG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKGI-KANVTRALPVGAQIPTIDNSGA KVIKIVSVKN--VKTIKGRTASAGVGDLVTASVVKGRPDMRNK---VVHAIIVRQKKEYR RADGLHVKFEDNGAVVLKDEK-GNPKGTIFKGPVAKEAVE-RWPAVGKVANIVL---MVK ----------------------QTKKQTIG---MG-IEV-PKDI---------------- -DTTTASVNCPF------------------TGELPVRGNIFTGEVISAAAPLTATVRIER KVFVSKYKRYKTMFSKTRVHNPAVIG--AQVGDVVEFVGCRPISKTKSNVIVRV------ ----------VR----------------------------------------------KH EGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKIFLFRGKTVE--------------------ELQAMSTDELLPLL SSQLRRKFARGL------THSEQVFYDKIKVKNN-------------VKTH-CREVY--- ------VLPFM----------------------------VNKTVKVYKG--------NSF E-----------DVIIQPEMIGHR----------------------------LGE----- ----------LVLTR-KRVMHGG------------------------------------- -------------MGVGA-SK-------------------------------GSANQSRK ------------------------------------------------------------ ----------------------------------------------------???????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- -MKT---FSTS-----WKSSTRVAKQRKYAYN-APLHLRGKK-LNASVSKDLQTKH---- ---------------------KVK-TLRVRTGDKVKVLRG--QFK--GLIGGVESVDLGD ARVFVLKAEIVKKDGS-KVKYP----------IHASNVEILELGKS-------------- ---------DKK-R----------------------------------------LGN--- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MAKKRKFIAYRRL--------------- -E-RPYTRKSKYR---EKSFIRAS-PANRIIRFNMGNV----NKAYDY-RLTLNSEADL- -QIRDIALESCRLLINRHS-EKKLGKG-EFYCTLRVYPHHHLRENALAS-GAGADRLS-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------M-ALN-DTLANLLSKMQNASKAGKDEVVVKP ISKVMIQVLDILKDHGYVTSYEIIEDGR-GNHIIVRG----------------------F ASINKCGVIKPRFNYKVSEIVKTEQ--------------------QYLPAKGFGVVIVTT SQGMMTLTAAKDKKLGGKLISYCY------------------------------------ MKVDKM------------ELEVPVLEGVTVTYANG-----VMSAT--GKAGTVEKVLR-N P-K----ITISV-ADGV-VVLT---AL-NAT---KKEKMFMNTYRAHLRNIMQGAAEG-F KYKLRICSGHFPMSAKIA---GDV--FE-LKNFLGEAFPRKLKLK--SGAKVSIEGE--- ----YITVESPNKEIAGQISADLEKLTRITN---RDRRI----------FQDGIYIVMKG DKDLLAQ-----???????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????--------- ------MYKYATQ----------------------------------------NITEKMA K----------------------------------------------------------- -----------ACMKSQA-ISTKQSVEIAKWL--KGKRVAEAVTLLEGVIEKKVAVPFTR FNW-DVGHKP-----G-----IGP-GRYPQKAAKQFIALLKLAKANAIDQSL-DGDNLVV FNIVAQKAAKQFKP------------SR--VRGQKAKS-THIEAVV-------MEVEAKA ----PTKAKRVAKVATQEKPEG-------------------------------------- ----------TAKPAQAATA-------------DAAEKPK-------------------- -------------------------------AAPKKTASVS--------KEPK-AKVAAE ------------------VSQ--------------------------------------- ---------------------MGKRIIAQR-------------RGTGSQRYRANSFQFK- GKAAH-----PSLSAD-TKSGV----ILDFIKCAAHTAPLAVVDYGD-ET-CLVLACEGM RVGDEVNAGS-------------DAD---PLPGNILTLAQIPEGTLVYNIEAKPGDGGKF VRASGVFGRVVSR-TP--A-GVVIRLPSKRQKVFHEKCRAAIGVLAGGGRTDKPLLKAGI AHYKAKARNHLYPKVSASAMNAVDHPYG-NKRTSRK---S-K----AMPVSRHAPPGRKV GMVAARRTG-------RNKK---------------------------------------- -------------------------------MSDT------------------NS-MRKL KIDKVVVNCGCGTDHIKLDKSLKLLESM-TGT-KPVKTKTE--L--RNATWGLRKGLPVG AKVTLRGD-AA-RAMIVRLVDAKEKVLELRNFDASGTISFGISECIDIPGVEYDPQIGII GLATTITLERP-GYRVKRRRYQKRSIPKAHSISKDEAIAFMHENFGVNLPVADEDEE--- --- >GCA_018304425 -----MT-VRRR--RRVNK-LRGKR--FHGHGNTKNAR-GKGARGGMGR-AGSHKHKFTS YWMT------------------------------------F--GV------KV-TLKPK- --PK-----PKA-----L-NLADFVR----LLPKWIA-EKRA-ER---------RGGQVL VD--GKKVG--IGKIL----GRGAVAEKL-VLSN---IAVSEGAKEKIV----------- --------------------EAGGSVGGEAASSEEDEE-FE--A--------EEEGAEEA EGAK------------------------------------------------------MI E--------------------RIFVEQGIKRMEL----------------EQYLKKEL-D KAGFTKAEVL------KTPLVTRIVVNVTRPGLAIGKSGANIRTLTETLGKRFGIENPQL EIK-EITQPALDAQAM----------ADKIKSLIER--GYSWRSVAYRTLRDIMEASAQG VEIIVSGK-IT----------GKG-------------GRKKQQRIA-------------- ----EGYMKKVGDQV-KLVDYAKAAAYPKVGAIG-------------------------- ----------IKVRIV---------------HPDT----------VFPDKV--------- -------------SIS--------EILKKK------------AAGEAG-KSEPAAP---- ----------------------------VAP----------------------------- --------VAVSPA-----------APAEAVA-EVP------------------------ --------------------K---------AEAKA------------EAKAGTVEGKKAA AEAKPV------------------------------------------------------ ---------EPVSGEAK-KEPKAV------------------------------------ ------EAAA-----P-------------------------------------------- --------------------------------TAAT------E----------------- ------GGETVAGQ-MGHVRASQGGVTAVV-----------DAKAETKAEVLSLEGKKLR EIGLPRVFES-EVDLGLIKRAVIAVQTGRIQPKGPSTRAGRDMTAQYIGSRQ-K-PAMYR TINVEHARLPR-LRN-RRYLLQGRVAGVPHAVGGPRVHRLN-----KDRVIVERINDKER RKAVAAAIAATADVALVRARGHRFE--AK-R-LPLVVEARFEELVKAREVAAVL---TAL NVYGDVEKAKAR-KKVRPGRGKTRGRKYKRAKSLLIV-T-E-KPAK-------------- -----VYKAARNLEGVDVVEVRNLNAELLAPGTLPGRLTLWTEGA---LNALAKYLVN-- ------------------------------------------------------------ ---------------------------------------------MTEINT---YAMPFR RRREERTNYKKRLALL-KSGKLRLGVRKTNNNSQV--------GDECLVMAQSSEL-RKL GW----TRHTGNLPAAYLTGYLCGKKAKKQ-SLLEAVLDIGLLTPVHGSTIFAVLRGVVD SGVGVAC--DKEVFPS------DERATGKHLG---------------------------- --GDATQLFELVKKEIDAK---------YGG----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAI-NATPTKGLTKKSWCTCADNSGA KICEIISVFG--FKGKKRQQPQAGIADLVNVVVKKGKPEIRKK---VERAVIVRVRKEYR RVDGVRVKFEDNAVVLVDDK--GLPKGSEIKGVVAKEVGE-RWPKVAGLAPAIV---MAR ----------------------------------------EVGV-----------C---- -N----DGKCAV------------------HGGVKVRGNIFTGRVVSAKADKTAIVERTL THYVHKYERYKNVRSRLVAHNPRCIG--AKEQDVVRIGETRKLSKTKAFTILSV------ ----------EG-HAK---------AVSHEDVGKAFKEKKG------PKGKAPVKEEGKE ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MAKDFNFRGIALD--------------------QLQEMDETQLGRLM TSRGRRNLRRGQ---------DKALLKTVDRALEAK-KHGKEP--KPIRTH-KRDAM--- ------ILPKM----------------------------VGLRFLVYKG--------KDW G-----------QVDIVEKMIGHY----------------------------LGE----- ----------FALTR-KRLSHGK------------------------------------- -------------AGIGA-TK-------------------------------SSTAITAR G----------------------------------------------------------- ------------------------------------------------------------ ------------MQKARIKLSSADYAKLTDICVRILDVAERTGVKHSGSIPLPTKKLVIP TRKSPCGGGT-------ESYEHWQMRIHKRLIDI-ESDERTLRRIMRVEIPENVHMEIEL KE---------------------------------------------------------- -----MGVA-------LTESSKPGKQRKAWYN-LPLHKRKVL-VSAHLSGELRKSL---- ---------------------GKR-AVPVRKGDKVKLVRG--GRA--GFSGKISRVDRTK GFVFIEGLKRRKADGK-EILVP----------VRPSNLVIEEIESA-------------- ---------DAL-RLG-----------------------------GKAAKKGKERKG--- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MG-LRPGHCYRN-------------TGH KQDRAYTRVAITVP--RKNFIGAT-PGLRTRQFNMGNP----TKKYSH-LVDLVLEETC- -QVRDNAIESARLIINRFM-IKRIGKD-DYFMRIRLYPHHILRENKQAQ-GAHADRIQKG MSHPFGRPIGRAIRVKS-GEVLMSVLV---N-KDHIALAKEGLLRAKARM--PCTVHVE- VGTDVESIGTLPRRAIEEKVVQE----VKETAESVAAAGAEGAAAGAAG---TEAGK-GG A-AAAPTA---AGPT---AGGKEAGKGSEKKGKK-------------------------- -----------------------------M-TRT-DPLADALINIKNHEGVSKRLCMVRP ASRLLGEILRVMQEKRYISTYELVDDGR-EGLYKITL----------------------L GKINECKAIKPRYAVAKDEFEKFEK--------------------RYLPSVDIGTIIVST PQGVFTHADAKKRGIGGRLLAYVY------------------------------------ -MASGT------------EIIVALPQDVQAELTGN-----TLKVR--AGGKEVVRVFK-G P-G----LSLEK-RENS-VMVK---MD-QDK---KKKRAILRSVASHIENMVAGLKQG-Y EYRLEIVYSHFPISVKVT---GNA--VE-IVNVGGAKHPVKSPIVG-KDTRVEIKGK--- ----DILVRGVDREAVGQTAANMERATRIKG---KDIRV----------FQDGIYIAYKG VKK--------------------------------------------------------- ---------------------------MVRIHKPHSGSKAFYPRVRARKETPSFSSF-P- APADVK---GASPLNFLAYKAGMVHGMGRNEAPKTTSF--GLEVSVPLTVVEAPPLRVYG VRAYKHS--VNG-LK---TVGEATVEKPDKF-----F-----RERV-------------- ---GDWF---K--------RRKSKKKKDRPAHKT-------------LADLEKL------ ---KS--QVDELRLLVHSQP-----SLTQSGKKVADVSEVKLSGSL-D---EQFAYAGQK LGN-ELTVQEVFKERQFVDVKAVTVGHGFTGVVKRFGVKSHRP--KA-KTQNV--VGSI- GPWH-PATVM-WTVARAGQMGYHNRTEFNKRIVRIS---DDLG--EVNPPAGFPNYGVVK NDYLLLGGSIPGPEKRAVALRFASR-PTPDNRYFLS------NVKVISPKRRKVHA--DD KVAVVELEEKAAHKVRVEEEKKEAKKSAADLIKE----------GLEGKKK--------- ----MVKENYQVD--------------------------------------LGENQAKIA K----------------------------------------------------------- -----------AVHANAN-ASVKFATEIAREV--KGQRLDSSIQWLNRVLAHEDFIPLRV YHK-KVPHRK-----GRAKSFGKA-GRYADKTVKVFLKLLHAVKANADVKGL-DSENLVI WHSFASIGFRRVSHQA-------K--GKISGKMRQAKS-AHIEVVV-------REAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRTRTQR-------------AGKGSPTYRA-SGRGV- ADVKY--VDYNEPQKEGVFRAE----VMDLVTDAGRTGIVAELLFEDNRR-GFQVAPEGI SVGQNLQYGK-------------KAA---LDVGNVLPLGEIVEGCPVFNIELNPGDGGRL VKSSGLYGLIVTK-DK--K-YVYVKLPSGKTTQLNPLCRATIGLSAGGGRVEKPLLKAGS MFHKMHASHHKYPLVRGVAMNPLDHPFG-GSQH-HA---G-K----SKSTSRHAPPGRKV GAIASSRTG-------RKKK---------------------------------------- ----MVEQRQAPIA-----------------GN----------------------PMREI RIAKVTVNMGVGQTGEELKKAETIMQRL-TNM-KPLLTVCK--V--KNPTWEIRPGLTIG CKVTLRDE-RA-IEFLKRALQARENKLAAKNFDLHGNFGFGIKEYIDLPGTKYDPKLGIR GFDVLIALERP-GYRVKRRKLAKKRIPRHHAVSKAEAVEFVSTRFGVEV-K--------- --- >GCA_016187385 -----MV-VNKR--KKHTR-FRGNR---HYHGSHKKHK-GAGGRGGRGD-AGLHKHNWTW TVK-----YDPH--------------------------H-Y--G-------KR-GFKRHP SVVR--HL--KT-----I-NLKDIDS----MVDKLVE-KKLA-GE---------ENGKIK IN--LEKIG--YDKLL----GAGRITKPI-IVEC---KYFSKNVEKKLEQAGG--KLV-- KL---------------------------------------------------------- ---------------------------------------------------------MAV E--------------------KVFVKELIKEAEI----------------EEFLKKRF-E RAGYSHTEIQ------RTPLGTRIIVHVNTPGLVIGRSGRRINEITEEIKHKFGFENPLL DVR-EVDDPLLDPNIV----------ARKIARSIEK--SVNYKKVANYYLDKVTEAGAAG ILLEISGK-I------------GGV------------ERSRRQKFK-------------- ----KGFVAHSGDYAERMVDTGYTQAIIKAGIIG-------------------------- ----------IKVKIMK-------------NMPV-------------------------- ------------------------DIV-------------LEK----K-VEAG------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MKVDVLDLNGKPAE KIELPKVFEE-PVREDLILRAVLATQSRKRQPYGSDVMAGKRTAAHYHGRRR-Q-R--YS MMSKETARLPR-LHAKTVPFLTMAARFVPQAVKGRRAHPPK-----VEKVWEQKINRKER RKAIRSAVAATAIKEFVLKRGHKVD--AI-KEFPIVVDDRLQELKKTKEVIEFM---KKI GLEKELERISE--RKIRAGKGKMRGRKYKTKIGPLFV-V-T-SN-G-------------- -----MSKAVNNLMGCNVCNVKNLSAEYLAPGSAVGRLTIFTKSA---INELK------- ------------------------------------------------------------ ---------------------------------------------MKLSPK---YKMPFK RRREGKTDYMNRLRLL-KSGMPRLVIRKSLRYITAQISDFDKKGDKTLIAVTSNEL-KKL GW----NYACDNLPAGYLTGLLVGKKALDK-KITEVVLDSGLYSSVKGSRIYSVVKGALD AGLKIPI--DQEIMSG------EERIKGEHIAT-NE------------------------ KFKSLPSEFEKIKQKI------------LGG----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKGI-KASVTKGLNVGSYLTCADNSGA KLLQIISVSG--YKGRRKRMPKAGIGSLIKVSVKEGDPKVRKQ---MFNGVIVRQRQEFR RPDGMRISFEDNAAVLTDEK--GAPKGTEVKGPIAKEVVE-RFSTIGKIATIVV------ -----------------------MKARNIG---VD-AKP-PSKE-----------C---- -S----DPKCCW------------------HGILPVRGNIIKGKVVSAKATKTAIISRSY LNFVPKYERYERRHSKITAYNPTCID--AKEGDIVTLAECRPISKTKHFIVIEK------ ----------VG-------------------------------------------G---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MAREFSFRGKTFE--------------------DLKKMSIDEIARLL PSRERRTLKRGM------TEEQKKFLEKTRKNPDKF-----------HKTH-LRAMI--- ------ILPEM----------------------------VGKKLGVYRGGAAQGDKSNKW F-----------TLEVKPEMVGFR----------------------------LGD----- ----------FAIPV-KRVQHSS------------------------------------- -------------PGIGA-SK-------------------------------STKHSSMR TT---------------------------------------------------------- ------------------------------------------------------------ ------------MQTARIKLSGRNIQELDSICNEIREIARKFGIDYHGPIPLPTKKMKLT VLKTPSGDGTGH---GNATWSKFEMRIHKRVLDV-QADDRALRQIMRVNIPQDVRIEIKL LN---------------------------------------------------------- -MKR-----PK--------SKKPGKQRKFLHT-APLHLKRKI-LSSHLSKELREKY---- ---------------------KRR-AMPVRKGDEVQVMSG--KLK--GKTGKIARVNFKK YRVYLEGVTRKRTVGT-EAQIS----------LSPSKLKIISLNLD-------------- ---------DKK-RQ-----------------------------------KIIERKGV-- -----KI----------------------------------------------------- VTEQPSTVQSK------------------------------------------------- --------------------------------MAGLRPGRSVRRI--------------- -E-RPWTRYSTKK---SKSYIPTL-PGVKIHTFNMGEP----NPNFDA-TLNLVAKNGV- -QLRDNALEAGRIVAQNFL-EKKLAK--NYSMKVLVYPHQVIREKPLAQ-GAGADRYSRG MKLAFGKPTRRAVQTRA-GQSLIKLKTFKAN-IPT---AKLALKRASAKL--PTPTRI-- ---------------------V-----VE------------------------------- ------------------------------------------------------------ -------------------------------MLQ-DTLADALTVIKNAEKIGRRECTI-K SSKLLEDILKIMKDNGYIGNYENVKDGK-GNLLRVEL----------------------K GKIIDARVIKPRFAVKTDEYEKWEK--------------------RFLPAKNIGILILST PKGIMTHYKAKESNTGGRLVSYVY------------------------------------ ----MY------------SREMKLPEGISLEINAN-----KVKVS--GEKGELKREVKLY Y-G----MKIQK-EDDK-LKVI---SE-SDD---RKAKALVGTVAAHIRNMAKGVTKG-Y TYHMKIVYSHFPVTVKVE---GSK--FI-VQNFLGARTLRTAKIV--GDTKVEINGQ--- ----DVTVAGIDPEDTGQTAGNIELATRIVG---FDRRR----------FNDGIYIGKKE ------------------------------------------------------------ ---------------------------MPEVKKPREGSKGYWPRKRSIRIYPSVTSY-P- E-TD-----KAMIMGFAGYKAGNLHAMMLDNKKGSITF--GQEVAVPVTILDCPPLKVIG IRAYENS--PYG-LK---VFSEAITKDLPKD-----M-----GRKM-------------K V---------GNF------KTDEK-----------------------LMGMEKN------ ---LG--KISKIRAIVSTQP-----RMSGVRKKTPEVFELEIGGKDAK---EKFDYAKSM LSK-EMTAKDFTKEGELVDVIAVTKGKGMQGPVKRFGVKVQNR--HAKKKRRH--VGSL- GQER-PGKVR-PTVAQAGQMGFHKRTEFNKRILKIGD-----G--DITPKNGFVRYGTVK -NYVMIEGSVPGSKKRLIMLRPPIR-----A-GKVK-FLLP-EIREVVK----------- ------------------------------------------------------------ --------------------------------------------------------MKTA I----------------------------------------------------------- -----------AKETSAP-VSFKHSKLLLKIL--KGKKVDRAKKLLENLLEEKRNLD--- -------------------------GKHYTKTAKKLLGILESAEANAKNKTM-DTEKLFI KNARVDKAEKLIRAK-----------SRVNLRGRAAKR-SNIEIIV-------EER---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRLIVQA-------------RGKGGPRYKVPSHRFL- GKVEY-------F-----PYGTFTAKVVDIMNDPGHFAPVMLVKAEGKEI--LHIAPEGI QAGSEISYG--------------GDK---PYLGNVLQLSNVPVGTRIFGIETWPGSGPKL CRSTGSYATVTNT-TG--N-KVIVIFSSGKEKIMDGKCRAMMGIPAGGGRLEKPFVKAGQ KLKAMMARGRLYPRSSGVAMTATDHPYG-GRKK-----HA-K----FKTVSRHAPPGQKI GSIAARRTG-------WKRK---------------------------------------- -----------------------------MQEN----------------------PMRQI RIEKITLNIGCGDDKQKIEKAQKLLEML-TNR-KPVITKSK--K--R-STFGIPKGKPLG VKVTLRKK-PA-EEFFERTLKAFDNNVKNSNVDSSGNINLGVREYIDLPNVRYSPQIGMF GLDVAVTLERP-GFHIKKRRIKKSIIGKSHKIYKEDAINWLKR-RGVNV-E--------- --- >Bin498_genes -----MN---KR--TKNSR-HRGSH--THSRGAKKKAR-GSGHRGGVGM-AGTGKRGDQK KTKITKL----------------------YANK-----Y-F--G-------KVIALRRKQ APK----L--KT-----V-N----LRD----IK--SD-K--------------------- -D--YT-----GYKIL----AEGEAQKGL-KIKA---TAASKQAIEKIKAAGG--AIE-- LPQPKP--------------------QPEKPKKKDKSEEQ-------------------- ----------------------------------------------------------ME E--------------------KKFVNFKKEELGV----------------KEYIKKSL-G KGRISNVSIE------YTPVGEKIIIATSKPGLVIGRGGEKIEELTRVLKKRFHLDNPHI DIQ-EITEPYLDAQLV----------ADEIAVILERRGHLQYKLVAYKMLEEIMKAGAQG VEIVLSGR-L------------PS-------------ERSRRWRFA-------------- ----KGYLKKTGEPA-KLVKRAQAQAKTIPGVVG-------------------------- ----------IQISIL---------------TPDT----------ILSDRI--------- ------------------------T-V------------D-DKLRKK--IQENA------ ------------------------------------------------------------ ----------QPVE-----------EEPEEKPV--------------------------- ---------------------------RSPKR---------------GASQRKSKSEKAR SK---------------------------------------------------------- -------------SESNSKK---------------------------------------- -----KETKK-------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------MAKATLYDTKGKNKS EITLPEIFNS-TIRADIVQKYFEA--DKFPQPHATNPEAGKRQSASGTISHK-R-HDWKG HYGRGISRIPRKTMWRRGTQFYWVGANIPGTKGGRRAHPPK----GIGKE--KSINKKEI QIAMNSALAATINKQQILNRYETLE--TAPE--PAVIEKLPE---KTKDFLQTL---NTI -FKNI-PQILKQ-KTIRPGKGKSRGRKYKSNAGLLIL-T-G-EKEKP------------- -----------TTKQIQTIPINEVTIADLYP---LGRLTLFTKQA---IEEVSSPKSQEP TVLDDRQSSKFSGTLRRESPQRSEELRSKSESDSKKETKR-------------------- ------------------------------------------------------------ -----------------------------------------------------------K GWPKEKAGSLKSIPAAYLTGLLLGNKIKDT---KEAILDIGLQRNMHKSRIYACLKGLVD AGINIPH--NEDALPN------DEELK--------------------------------- KNEELAKILDKVKGEIK------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAV-TAKPTRAFNIGSQMIASDNSGA RIVKIVSVKH--GKSTKKRQQYAKLADWVKVSVRAGKPDMTGQ---VFDAVVIRQKREYK RKTGERVMFEDNAVALLKDDK-GNPKGTIIKGPVAREVQE-RWPQVAKIAQFVL------ -----------------------MTEQKLKS---------GAK----------------- -----------V------------------ENTVATRGRTFQGIVTK-VFPTRISIEIER TVYMQKYERYYKKKSKLHARIQEGM--EIQIGDIVKIQETRPLSKIIHFMVIEI------ ----------VK-------------------------------------------KAEVK EETQ-------------------------------------------------------- -------------------MEQ-------------------------------------- ------------------------------------------------------------ ----------TSVKIKEQKYRGQDLA--------------------TLKTMDVREVAKFL PARSRRSLMRHF-------EVVENFIKACEKKQANK---------KKIKTH-QRDIV--- ------IVPQM----------------------------VGLTIGIYTG--------KNF E-----------DVQITHQMIGHR----------------------------LGE----- ----------FALTR-KQVKHGA------------------------------------- -------------AGIGA-TK-------------------------------SSRSDKK- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKVRIKLSSINVDELNPVMVSIGEIAERAGVAMRGPIPLPTRKMKVT TRKSPCGDGT-------ATFDRFEMRVHRRVIDL-PAEDRVLHPIMKLQIPRSVQIKIEM KE---------------------------------------------------------- -MKS--TFNTK-----WTASKQPRKQRKYTAN-APLHIRHKF-LSAQLSKELRKKH---- ---------------------NKK-NIPLRKGDEVLIMRG--SHK--KKKAKVISINLTK SKVVLEGIQQTKRDGS-KVAIP----------FHPSNLQIQTLTLD-------------- ---------DKK-RIKAL----TGKEVSSPKSQEPTVLD---DHQGSKSSGTLRREAS-- -----QSSDEKARSKSESDLKKDSQPNKKDSLNN-------------------------K SSSQTKTREKKQNGPPKKTNNN-------------------------------------- --------------------------------MVSLRKAGAYSKK--------------- -IVRPYTRTSRNR---KKAFIKAV-PQNKIVKFDLGNKAAFLKGQHKF-RIRYVTTEKI- -QIRDNALEACRTLINKIL-EKEIPGQ--FYFMVKVFPHHILRENKTAA-GAGADRLSSG MKHSFGITIGRAAIVNK-GKEVFVITT--AT-EKAARTARAALSKVKPKV--PCRGKI-- ---------------------L-----FEKLD---------------------------- ------------------------------------------------------------ --------------------------------MSQDTVADALNQIMNAKKAGKEVVEITM HSKLLHTILALAKLKGYVKNYEIKNN-----ILTIEL----------------------G N-ITKCQAIKPRYTIMVSDIEKYEE--------------------RYLPAKDLGILIVST NQGIMTHQTAIEKNIGGCLIAYMY------------------------------------ -MRTKI------------QESIQIPEGVTCNLEDS-----NITCA--KEGKSTTKEFK-T P-K----INAEL-KDNT-ITFT---CE-KGN---KIQYKKIKTYIAHLINIFNGLEES-Y TYKLEICNVHFPMQVKLE---GQE--LS-ITNFLGETTTRKAKIL--PNVEVNIKLP--- ----EITLTSHDREAAGQTAANIEQACKIKG---KDVRV----------FQDGIFITEKP SKRLEEKQE--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------TILETPNMKVFA IRFYKD-------CQ---AIKD-LIVSNDKE-----L-----KRKL-------------- ----KVP---K--------TV-KD-----------------------IE--KDAPK---- ---PE--EYDNINLIVYSLP-----KQAKI-KKTPDLIEVAVHAS------DKLAFAKSL IGK-EITQNEF-THNKLLDIRGLTKGKGTQGPVRRFGIGLKSH--KSEKGRRN--PGSL- APWH-PCYIT-FRTPMPGQLGMFSRTHYNFNVIDSNT--ISEK--NINPKKGFKKYGNIN TTYIIVKGSVQGPPKRQLVLTPAQR---P-S-KKQA-KQTY-DFLEVITE---------- ---------------------------------------------------????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????????????????????????-- ---------------------MGKRIISQA-------------RGKGSSTYRVRRKGFS- HKIQYP-S---------K-PGK--AKILKLIHSAGHTAPLMKIQVENQI--TFIPAFNNA VVGEEIEIGG-------------NE----IKDGNITQIRNIPVGIQVHNIERNPGDGGKL MRSAGSSAPVFKVYPH--N-KISVMMPSKKEVILSGDCRVTIGEVAGEGRKLKPIVTAGR KYYRMKARGKLWPRTSAVKMNAVDHPFG-SGRGKRI-----K----SKIAKRNAPPGRRV GHIRPRRTG-------RR-------------------------------MTT-------Q QLTPATETPLKEPVAPSNTGQDLQDNKSSKGEN----------------------PMRKI FVEKVILS--CGGVDKELEKAKLLLKFL-SEM-EPQVIVSA--K--RIPNFNVRPDLEVG TRVTLRGE-KA-TQLLKRLLGAIDNTLKKKQIAEN-HFSFGIKEYIEIPETTYQREIGIR GLSVTVDFARA-GLRTKRKKIKQGKIPKKQKVSKEEIIEFMQQNYNTEV-VGK------- --- >GCA_003649025 -----MV-VHRR--KKKVK-QRGHK--THGWGSKKKHR-GAGNRGGRGM-AGTGKRGDQK K---------PSIWA----------------KR-----Y-F--G-------KR-GFKPKG IIRK--AT--NP-----V-NLLVIEA----KIDEWLR-EGAA-KK---------VDDFYE VD--VRKLG--YDKVL----GYGKLTRKY-RIIA---PAFSKEAEEKLKSAGG--EAV-- V---------------------------EK------------------------------ ----------------------------------------------------------MI E--------------------KKLLSERSKDFQI----------------EEFVMNSF-R NVGVSSVKVQ------RTPLGEKIVITALRPGLVVGREGQNIRRLTAELKKKFGLENPQV EIQ-TVDNPFLDPHIV----------AERIANTLERFGITRFKAVGHRAVQDVMNAGAIG VEITISGK-V------------PS-------------SRAKTWRFY-------------- ----AGYLKKCGDVAIEGVKKAYAIARLKPGV---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MKVDVVDLGGKVVG KVDLPKQFSE-EYHPNLIKRAVETIQANKRQPYGAKPDAGKRASVRLSKRRR-D---YRA SYGRGISRVPRKILLRRGGQFYFVGAFAPGTVGGRRAHPPK-----AEKDWSKKINKKER KKAIRSALSAAFNRSLVEDRGHKAP--E---NYPFVLIDDFANLGKTKEVKQAL---EAL GLKDEIERSSK--KKVRAGKGKLRGRRYRRKVGPLFV-V-H-EKCN-------------- -----LMKAAANIPGVDVVLVKNLNAEMLAPGGKAGRLTLFTKSA---LDVMEKENLFM- ------------------------------------------------------------ ---------------------------------------------MKRKNKI--FTVQFR RKREGKTNYRKRIELL-KSGKPRLVVRPFLKNIIAQIIEFDKVGDRTIASATGYEL-EKF GW----HFSKGNIPAAYLTGLLAGRKGLKK-GIKEAVLDIGGKTPIKGTRVFACLKGAID AGLDVPH--SEDVFPS------EDRLRGEHIKRYFELGGWNS--KSQFAEMK--K--KGV DVEKITNIFEEVKKKI------------MEM----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFTFRGKTLE--------------------ELKQMTLDQFAELL KARPRRKLKRGL------TEAEKKLLKRIREKPD-----------KKIRTH-CRDMV--- ------IIPEM----------------------------VGLTIYVHNG--------KSF V-----------PVSITPEMLGHR----------------------------LGE----- ----------FALTR-KPVKHSA------------------------------------- -------------PGVGA-TR-------------------------------SSAAISAK ------------------------------------------------------------ ----------------------------------------------------------M- ------------PQKARIKIVSTDINKINQVCQYIKDIAEKTGVVMRGPIPLPTKRLRVT TRRSPDGEGT-------ETWDRFEIRVHKRLIDL-GIDERALR----------------- --------------------------------------------------------MPIF ALRT--TANREDQVMDFIISHVEKKGLNVWSIVRAHGMKGYIFVEAESKADVERAAAGVP YARGVLPGELAYKEIEHMVEPVKR-EIDIRKNDIVEIISG--PFK--REQAKVTRVDKLK EEVVVELLEA-------AVPIP--------ITVKIDAVKVIRREGE-------------- -------------------------------------------------------ESE-- ------------------------------------------------------------ --------EE-------------------------------------------------- ----------------MNQTTIFIKHLSFEKSMARLRKGVAYRNL--------------- -E-RPYTRVSKFR---EKSFIRAT-PRVNIIKFTMGDP----NGKFEY-RLDLVSKDSI- -QIRHNALEASRLTVNRYL-EKKLGKK-GYHFKLRVYPFHILRENPIAA-GAGADRVSKG MKQSFGKPIGSAAQINA-GQSIMFVDV---N-KADIPVAKTALERAIKKL--PCKCTI-- ---------------------K-----ISEIKA--------------------------- -------------------------------------------????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????------------------------------------------------ ---------------------------MPRKRSPRKGSLQYWPRARAKKIRPRIKKI-S- --LD-----KAGLSGFAGYKVGMVHVCLLDERKNSMTK--GERITVPATIIECPPLRVFG VRFYKIK---NGTFV---SGETILNQKLDKE-----L-----KRIV-------------- ----QLP---K--------KKTKS-----------------------IDEVK-------- ---LD--EYDDLAVIVYTMP-----KLAGIRKKKPELFELSIGGKDIK---EKVEFVKGL LDK-EIKVSDVFSEGALVDVHAVTKGKGFQGAVKRFGVAIRQH--KSEKTKRG--PGTL- GPWT-PKRVS-WTVPQAGKMGFHQRTEYNKLILKIG----KAD--EINKDGGYLNYGILK SDFVLLKGSIPGSRKRLIVFTAAKR---P-N--DKL-LMVP-KIEQIIK----------- ------------------------------------------------------------ -----MGFNYSI----------------------------------------KYDAEKEA R----------------------------------------------------------- -----------AVGLGMR-ISTKHSVEVCRML--RGMELQKAKDLLQKVLEKKIAVPYRR YRR-DLGHKK-----G-----IEA-GRYPEKVCKEILKLLKDVEANAQVKGL-NTANLVI KHIAAHNGGKPLRY------------GR--RRGRTAKR-THVEIVV-------KEK---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKSLIVQR-------------RGKGTHTFKALSHRYK- GAAKF-----LSLAEG-KLEGV----VVDIVDCPGHSAPLMVVRYANGNE-ALMIAPEGI KVGDVVEIGS-------------GAS---VKTGNVLPLGEIPEGTSVYNIESVPGDGGKF CRASGSFAKVVGK-LP--G-GVLVKLPSKKERLFNANCRACIGVVAGGGRLEKPFLKAGN KAKAMWARNKLYPRTSACKMNAVAHPFG-NTRSARK---S-K----RKPVSRNAPPGRKV GSIAARRTG-------RKKR-----------------------------??????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??? >GCA_018920365 -----MV-VRKQ--RKTTK-KRGHR--TAGYGGQKKHR-GGGSKGGKGN-AGLHKHKIMK MLK-----YDPD--------------------------H-F--G-------KK-GFKR-- VFAK--KP--NA-----I-NIDELNK----IIENMIK-EG---KM---------KKDNIK IN--LDELG--YEKLL----GNGQVKYKM-EIQA---KSISKNATKKLEENGC--KII-- TVD--------------------------------------------------------- ---------------------------------------------------------MSV Q--------------------KFFIKEGIKESQI----------------EEFLRKKF-D KAGYSHSEIQ------RTPLGTRIIVYCEKPGLVVGKSGKKINDITLEIKSKFELENPML DVK-EVEEPYLDAQIV----------ANKIAKGIEK--GGFYKKLANYYMERVMQAGAIG VEIRTAGK-L------------GG-------------ERGRFQTFK-------------- ----QGYIKHSGYYADTLVAKGYATAILKLGMVG-------------------------- ----------VKVKILT-------------QMPE-------------------------- ------------------------D-L-------------NEK----S-IEGI------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----LNEEKGSKENE--------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MRANVYDLNGKTKE QIELPSVFSA-SVRDDIIRRAILALQSQKRQQYGSDPEAGLRSSAEYHGKRR-M-R--YQ MINRDMARLPR-LHR-TTPHLNFRVRLVPQAVKGRRVHSSK-----AEKIFAQKINNKEL KLALKSAIAATADVKLVKARGHQVE------KLPLIVEDSIQKIKKAKEFEKIA---EKM ELTREIDRCKD--KRQRPGRGKMRGRRYKTKKGILVV-V-A-KDEG-------------- -----IIKAVSNIPGMDAVTVDKLSVEDLAPGAMSGRLTIWSKSA---IEKLREM----- ------------------------------------------------------------ ---------------------------------------------MKIKQT---YELPFK RRYKGKTDYRARLALV-KSGLPRVVLRFTSNRAIAELIKYEAKGDKVLAYATTNDI-VKL GW----KHSKKNTPACYLLGYMIGKLSAKV-KVKEAVLDLGLHK--SSSRVGAFIKGMTD AGLQVPH--SEDIIPD------EKRIKGEHIINAAKSIKNKNQ-------------FSKA KPDNIAKDFEEIKKKI----------SGV------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAL-KAKVTRGIPVNSLIECVDNTGA KILNVIAVMG--YKGVKRRMPACGVGDMIVCSVKTGTVKWRKQ---VVKAVVIRQKKEYR RSNGIRVSFEDNAAILVNER--GEPVGSQIKGPVAREAVD-RFSVIGKVASFVI---M-- ------------------------KAKDIG---YD-VKP-PEKS-----------C---- -D----DPKCPF------------------HGKLPIRGKILKGIVVSDRMDRSVVVRIDY IHYVTKYERYEKRKSRISAHNPECID--AKKGDRVTIAECRPLSKTKAFVVIEK------ ----------N------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MAKQFTFKGKTIE--------------------ELKQLSLENFAKLV TSRERRTLLRGL------NDRQKKLLENLRKYPDKF-----------HRTH-ERDMI--- ------VLPEM----------------------------VGRKIGVHNG--------KEF V-----------SLTIADYMVGHR----------------------------LGE----- ----------FALTR-GRVKHSS------------------------------------- -------------PGVGA-TR-------------------------------ASKHVPLK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQMARIRLSGRDPKKLDSICNEIIDIAKKFGVDWKGPVPLPTKKMKVV TLKTPCGDGTGH---GNATFDRWEMRIHKRLVDL-QADDRVLRQVLRVQIPQDIHIQINF RD---------------------------------------------------------- -MKK--W-SPK-----WKASKNPKKQRKYRYN-APLHIKRKF-LSVHLSKELREKY---- ---------------------KKR-SLPVRKGDEVIVLRG--KYK--KRTGKVSRVDLIH EKVYIEGITRKKVAGT-EIPVT----------FNPSNLMITSLQ-E-------------- ---------DKK-RF-----------------------------------K--------- ------------------------------------------------------------ --------KSK------------------------------------------------- --------------------------------MA-LRPGRTVRRI--------------- -K-RPWTRVSQRKP--KKSYVVGV-PYPRIHVFEMGNK----TKQFEV-TLELKVENSV- -QIRENALEAARIVANKYI-EKVLGKE-GFFMKVLKYPHQILREHSLAT-GAGADRFSMG MRKAFGRPKGRAVIIHS-GETLMILKVDKAN-LDN---AKEALRRASTKL--PTPCKI-- ---------------------I-----VS------------------------------- ------------------------------------------------------------ -----------------------------MGMRH-DTISDVLSIIKNAEMVGKKECVT-P ASNLAKQVLLIMQKEGYIGKVEFIDDGR-SGKFKIEL----------------------K NRINNCNAIKPRYSTKYTEFEKWEK--------------------RFLPARDFGIIILST NQGLMTHNEAKAKKIGGKLISYVY------------------------------------ -----M------------EKELKIPEGFKVEIDGK-----KVTVSYNGKSLEKELKMS-- S-E----IKMSI-EGDT-FKVY---TD-SER---KKSKAMLGTVISHVKNMIKGLKDG-Y TYRMKIIYTHFPMNVKVE---GNK--VI-ITNFLGERTTRTARII--GDTKVQIAGQ--- ----DITLTGINKEHVSQSAANIENATRISK---KDRRI----------FQDGIYIVQSR E----------------------------------------------------------- ---------------------------MAAPKRPRRGSLAFYPRKRAKRIYPKIRGR-A- K-SD-----KVKPLEFCGYKVGMTTLSMIDTRKTTPTK--GEEITTPATIIECPPLKIIG ARFYTNT--NSG-LK---AVKDLIAIDSKKEK---YI-----GRKM-------------K L---------GEF------RPNEK-----------------------LEFAEKN------ ---ID--KIDEISLLVRTNP-----HVSKLKKK-PEIFEIDIGGNDVK---EKLKYVKEN LGK-EINASDIFREGEFVDVIAITKGKGTQGVVKRFGVRLQFR--KDMKHHRQ--IGTL- GSQS-PGRIR-WTVPRAGQLGFFQRTEFNKRILKIGND---PK--EINPKSGFTNYGIIR SSYLILQGSVPGPKKRLIALRLAAR-----S--KIG-FLPV-ELK--------------- ------------------------------------------------------------ -------------------------------------------------------MDKTA K----------------------------------------------------------- -----------AKRTNAR-VSMKDANVIFKKL--RRKKLEKAKAFLQRLIDKKEDID--- -------------------------GKYYTGACKVILELLEDVQANAEAKNL-DTEKLFI KKLAANKSFTFVLPK-----------SRITHRGRRAKM-CHLEVEV-------EER---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRIKARA-------------RGKGGPRYRAPSHNWA- GKVEY-------YLSDKISYGV----VKDIIHDSGRNAPLSVVEFPDKTV-KLHIAVSGI KVGDKINY---------------WNG---LSTGSVLPLHKIPEGMKICCIETYPGSGPKM CRTSGSFATVLGK-IK--D-KVRLMFPSGKIREINQNCLAMIGIPAGEGRKEKPFVKAGQ NHYKSLARGKFWPVVRGVAMGPVDHPFG-GKTK-----PG-I----PKSVSRHAPPGRKV GSISPRRMG-------KRKK---------------------------------------- --------------------------------------------------------MRKV RLEKVTLNIGTSTDKEKIEKGLKLFEML-TGK-KPVVTKTI--K--R-NTFGIAKGRPIG VKVTLRGK-EA-MDMLVKVFKAVDNSIKLKQIN-DGNFSIGVKEYIDLPGVNYDSNIGIL GFDCTVTLERP-GYSVKRRKLRKAKIGKKHLITKQETVEWIKS-LGVKI-IE-------- --- >GCA_003561825 -----MI-TNRT--KKCRK-LRGSK--THGWGAMKKHR-GAGSRGGRGM-AGTGKRGDAK K---------PSIWKD---------------RK-----Y-F--G-------RH-GFKMH- GVKI--KA--LP-----V-NIGIIDQ----NIDKYIS-QKLI-EK---------SGESYS ID--LAKLG--FNKLL----GSGKTEKKL-NIKC---RLASKKAVEKIEKAGG--SVL-- F---------------------------EDKNLIEQQKTKQS------------------ ----------------------------------------------------------MI E--------------------RKFVAEKKKEFQI----------------QETIAGNV-K GSGYSHTKLQ------RTPLGEKIIIFAAKPGLIVGRKGQNISSLTREVKGKFTLENPQI EIS-EIENINLDAQVV----------ADNIAQSLERFGSSRFKGIMHKTMDDVMSAGALG IEIVISGK-I------------PG-------------SRAKSWRVY-------------- ----SGYLKKCGDIAITSVSRAKVKAVLKTGVVG-------------------------- ----------VKVSIM---------------PPDI----------KLPDNI--------- ------------------------E-L------------A-EEPEVI--SE--ET----- ---------------------------AEEK----------------------------- --------P--EDK-----------EGSEK------------------------------ ---------------------------QEKKQ---------------------EQEKEDT KKPEEKPA---------------------------------------------------- ------------PKKKAAKKKTAK------------------------------------ ---KAKS----------------------------------------------------- ----------------------------------KN------EAKK-------------- ----------------------------------------------MKVPILDKSKKEIG QESLPQQFSE-EIRPDLIKRAVLSINSAEKQPYGSDPRAGKKSSAELSRRRH-S---YKT SYGYGISRVPRKIMSRRGLRMNWVGAFAPGTVGGRKAHPPK-----AEKNIEKKINKKER RKAIRSAISATMIKDLV-SKNHSIP--D---IFPFIIDDKIESLNKTKDVRNTL---VAL GLEKELQRIEH--KSIRGGKGKKRGRRYVRKTGPLIV-V-S-KDCS-------------- -----LIKSARNIPGVSARTVKSLNAKALSSGISPGRLTIWTKSA---VKELSEKKLFM- ------------------------------------------------------------ ---------------------------------------------MPKNKI---HKVGMK RKRERKTNYRSRIALL-LSEKPRIVIRKSLSNITVQAVEYSPKGDKVIASAKSREL-AAM GY----TMNRGNIPSAYLTGLLLGKRAMEK-GVKEAVADIGLNTHMKGSRVYAALKGAVD AGLKVPC--SEEIFPP------EERITGKHISDYAQKLKSESNEKYEKAFSR-CL--KHA APEDIPKQFEAVKSKI------------MKVK---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAH-KAKITRALPFGATIQTCDNSGA KVIRIFGVKR--AKTVKGRMPAAGVGDLVMASVKKGNPDMAKQ---VVLAVIVRQRKEYR RSDGTRIKFEDNAAVVMKDEK-GNPKGTIFKGPIAKEACE-RWPGIAKVARIIV---MKS NT-----------------GKKEKPRKK----------A-KSAE-----------C---- -N----DRHCPF------------------HGSISLRGRSFVQKVISTSPQRTATVEMER RAYIPKYERYEKKRTRLHAHNPDCIS--ASVGDKVRIMECRPISKTKHFVITEK------ ----------IS------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFTYRGKTLE--------------------ELKGISAKEFADLV PSRQRRTMLREQ------SDEKRTFMKNISTGN-------------NIKTH-CRDIV--- ------ILPSM----------------------------VGKTIRVYNG--------KEF V-----------AVIVQPEMIGHF----------------------------IGE----- ----------FALTR-KRITHSA------------------------------------- -------------PGVGA-TR-------------------------------STSSISVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLASIDIAKINEVCQYIKDIAEKTGVEMRGPIPLPTKKLKVT TRKAPDGEGK-------ATWERYEMRIHKRLIDL-AIDERALRLVMRVPIPEGLNIEIEM IDV--------------------------------------------------------- -MDK--DFSKN-----WISSKQPRKQRKYRHN-APLNVRSSF-MNVHLSKELIKKH---- ---------------------GRR-SMRLRKGDKVTVLRG--QFR--KSSGKVEKIDLKS SKAYVAGVETIKKDGT-KAPYP----------ISPSNLIITELKLD-------------- ---------DKK-RA-----------------------------------EAMQRK---- ------------------------------------------------------------ --------PGKPKED--------------------------------------------- --------------------------------MARLRKFVAYRRL--------------- -E-RPYTRVSKFR---EKSFIRAS-PHIKIVRYEMGDP----KKEFSC-ELELVSKAEL- -QIRHDALESARQTSNRVL-EKQIGKG-GYFLKIMVYPFHILRENPLAS-GAGADRMSTG MKKSFGKPIGSAAQIRK-GQRIMLLRV---N-KGALETGKKALERASKKL--PCSYSI-- ---------------------K-----VKEMKPVTIAK---------------------- ------------------------------------------------------------ -------------------------------MLN-DPLSNVLSKILSKNNAKNKECVVKP SSKTIKEVLRIMKDHMYIGEFKETEDNK-GKMISVEL----------------------I NNINKCGVIKPRFSVKSDGYEKFEK--------------------RFLPAQGFGILIVST SKGMMTNEQAKKAGIGGRLIAYCY-----------MHTA--------------------T KMKAKI------------IEEIELPEGIQAAMDGF-----FFSVK--GPKGELKKKFV-G E-G----ISISA-DGKK-IIVL---SE-NAS---KVQKKMINTFAAHMRNMVKGVQEP-F VYKLKVCAGHFPMNVSVS---GDV--FT-IKNFLGEKVPRTLKIR--QGANVKVDGK--- ----DVYVESIDKEIAAQAAAEIEKLTIVKG---RDRRI----------FQDGIYIVSKA GKEIK------------------------------------------------------- ---------------------------MAKSRNPRHGSMQFWPRKRAKSEHPRIRSV-A- L-LK-----ETSPCFFAGYKAGMTHILFRDERPNSMTK--GSSVFMPVTVIECPPLKVAA IRFYKKS--GYG-IN---PVGEILAKTNDKN-----L-----ARKI-------------- ----TLP---K--------K-EIQ-----------------------GKDIS-------- -------DYDDIRIIAYTQP-----SLTGIGKKKPEIFEISLGGEK-E---QKLAYAKEK LGK-EITLKDVFKDGQLIDTHAVTKGKGFQGPVKRFGISLKSH--KSEKKRRS--AGNL- GPW--QQSAI-WRVAQAGQMGYHTRTEYNKEIIMISA---KPE--DINLKGGFPHYGNVK NDYIIVKGSVQGHQKRLILLNHAVR---P-D-RKQR-AEKL-SIEHIRK----------- ------------------------------------------------------------ -----MKKNTSYS---------------------------------------KKIGENAA R----------------------------------------------------------- -----------AAGMSLP-VSAKQAVEICNSL--RGRELEQAKRMLKEASLKKTPLPFRR FTE-GAGHKP-----G-----IGP-GKFPVKACRQILSVLESAESNAHQKNL-DSSALFI AHICANRGPKTWRY------------GR--QSRVAMKR-AHIEIVL-------EENPEKK DASGQKQKHKKQEKAAEKKQKPL-----------------AQSQDQKSKETKKPEAKPA- --------EKEEKKQEPSAQSQDQKNKE---TKKPEAKPAE---------KEEK------ ----KHKPLAQSQDQKSKETKKPEAKPAEKEKAEKKHEPSSQAKK----KEPEIQEKKEA ------------------DKKPAEDS----KPKKSP-----------KGQGPEESKQK-- ---------------------MGKNLIQQA-------------RGKGGPTYRAPSFRYF- GKASH------LSHKG-LLGAE----VVDLLKCPGHSAPLAVLRYDNSIM-KLIIAPEGI RVGDKIQSGE-------------GAS---MEKGSSLKLKEIPEGALIYNIENQPGDGGKF VRASGNFAKIVTK-AP--G-SIMVLLPSKKKKAFNPECRASIGVVAGSGRKEKPFLKAGR KFFAMKAKNKLWPSVSGTSQNAVDHPFG-GTSSAHK---G-K----PTIAPKNAPPGRKV GAIHPRRTG-------RKKK---------------------------------------- -------------------------------MN----------------------PSQQI KVSKVTLNIGSGKDQSKLDKGIALLKSI-TGM-NPVQTVTS--K--RIPGWGLRPGLVIG CKVTLRKD-LA-EKTLLRLVQARDNVLKENQFDDNGNVSFGIPEYIDIPDAKYDPKIGII GLEVCVTLERN-GFRIKRRKIGKKKVPMKHRISKQEAISFMKEKYNIKL-EGE------- --- >GCA_007117065 ------M-SSNL--RKVKK-YRGHK--THGGGAMKKRR-GAGSRGGRGL-SGRGKRADVK K---------PSVWKI---------------KD-----Y-Y--G-------SP-SFTS-- H-RP--RP--VA-----V-NVSDLVQ----QLSLFEE-NGFA-KK---------TSQGYE IN--LSSAG--IDKLL----GSGAVSQTF-IVTV---ASASPRAVEKIVSAGG--SV--- -----------------------------HTEDDQEESEQ-------------------- ---------------------------------------------------------MAI E--------------------RKFIEQNIKEYRI----------------KRFIEENL-D RVGLSQVTLK------KTPLGDKIVIHASRPGLIVGRGGSNIQSLTRSLKEEFSLENPQI EIE-EIKKPDMDADIV----------AERICNSLERFGSARTKGIGHKTMMDTMRAGALG VEILITGK-I------------PS-------------MRARRWRFY-------------- ----AGYLKKAGDLAIEGVYVSKKMVTLKSGAIG-------------------------- ----------VQVRIM---------------PPTV----------DLPDHI--------- ------------------------T-L------------T-EDITQE--ISV-ENA---- --------------------------NSVQS----------------------------- --------AEQEIAAV---------SQEEVVG---------------------------- ---------------------------E-TKE---------------------ASVEQTE EEIVS------------------------------------------------------- ------------TQENTVSESSED------------------------------------ ---VSSDESADDTK---------------------------------------------- ------------------------------------------EGKQ-------------- ----------------------------------------------MKLAILSTTNTKKG DITFP--INE-AYRPDLIKRSVLSLQSRRRQPYGADPRAGLKHATNVAKRRR-K---YRG SYGKGISRVPRKVLSRSGLQFYWKGAEAPGTVGGRRAHPPK-----AEKIWVKQINKKEN RKAINSALCATLDVSIVQQRGHHVP--K---TYPFVLADEFETIEKTKQVRELL---ETL GFAKELERGEN--NAVS-----------------LLI-I-T-ESKT-------------- -----LAKAAKNIPGVDAVMFTAVNAELLAPGTHAGRATLFTESS---IKKM--EEFL-- ------------------------------------------------------------ ---------------------------------------------MTKNNR---YALPYR RRRSQKTNYLKRLNML-KSRKIRLVVRKSNMHTLVQCVQYFPDGDKVLLSASTKDL-SSY EW----NYSTSSIPAAYVAGLLLGKKALDA-GLADLIVDLGMQVPHKQGRLFAAVFGVQE AGVSVSV--SDEALPP------SERVNGSHIN---------------------------- --EAIAKSIAIIKKK-------------AGI----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKPI-SSSVTGGLQVGSRVATCDNSGA KIVEIISVLK--KKTTKGRRQTAGVGDMVILSVKKGRPDVRKQ---VMHGVVVRQKKEFR RADGMHVKFEDNAIVVCKDEK-GNPKGTIFKGPIAKEATD-RWPAVANVASIIV------ -------------------------MKEA---------E-KVAV-----------S---- -E----ST------------------------QYSTRGKTFVGVVVSAKANKTASVQWER RIFVKKYERYEKRRSKVAAHIPDHLE--IKEGDTVRIAETRPISKTKHFVITEK------ ----------ME---------------------------------------------EIQ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MARKEFRYRGKTLE--------------------ELNTLSRKDMTELF TSRIRRTLQRGY------PEEVKKAEAKILSKDN-------------VKTH-CREIV--- ------IFPQM----------------------------VGKIIKVHNG--------KEF V-----------DVRVQAEMIGHV----------------------------LGE----- ----------FSQTR-ATARHNS------------------------------------- -------------PGVGA-TK-------------------------------SSGAKSVR ------------------------------------------------------------ ------------------------------------------------------------ ------------MSKARIKLASADISKVNEVCEYIKDISTKTGVDMRGPIPLPTKRLQLT TRKSPDGEGT-------ATWERYEMRIHKRLIDL-GVDERALRLVMRVQIPEGLNIEIEI ID---------------------------------------------------------- -MKS--EYSSS-----WKKSVQPRKQRKYRVN-APLHIRGKF-LSAPLSKVLREKH---- ---------------------GMR-SLRVRVGDEVEILRG--SFK--GEKGAVERLDTGR SKIFVRGVDRVEPKGG-RKQIA----------ITPSNVRLIKL-VD-------------- ---------DAR-RFA----------------------------------KQ-------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MGKDRKFVAYRKL--------------- -E-RPYTRKSKYR---RYMYVRGN-PHRKIQRFVMGNK----ARTFTH-SVKLVSRTDL- -QIRHSALEAARMAANRRV-ETLAGRP-NYYMRFHVFPHHVLRENALAS-GAGADRLSTG MKKSFGKPVGVAAQVRK-GKVIVEIGV---D-KKHIAVAKGALELVKNKF--PNSYYI-- ---------------------M-----VDEVPTSTDLPA--------------ETFKKIA -------------------------------------------MVSQLGDVELLEVTEHT SASMVFICVDTRLESTQRSSVSKNIGD-HM-SLN-NPLANVLSAINNAERVSHKKVVLQN TGRVIEKVLAILQQEKYVESFEFIGGVR-GGTITVTL----------------------C QGINKIGVITPNFSVKFADFQKWEQ--------------------RYLPAKDFGILIVST SQGMMTHYQAQELGIGGRLLAYCY------------------------------------ -MKQAI------------TETITLPQGVQAEYVDG-----ILTVK--A-KNELKRNLF-R P-K----IAVSV-DAEN-ITLH---VD-SST---QREKKQLYTMKAHILNMIRGSQEA-H TYKVKVCSGHFPMNVSIS---NGV--LT-VKNFLGEAVPRKLVLK--KDVSVVLNGD--- ----IIEISSPYIERAGTQASDIEQLTKITN---RDRRI----------FQDGLYIIEKD GNAI-------------------------------------------------------- ------------------MG--------KKINAPRKGSLQYWPRKRAKRQHARVRTW--- ---KLS---E-GLLGFAGFKAGMTHVLVTDNRKNSITK--GQDISVPVTMVECPPLDIIG VRFYRKS-----------------QTRYGEE-----A-----ATEV-------------- ----RM-SAPKHLSRTTVWNATGS-----------------------LDEIN-------- ---PE--EYVRATLIVSTQP-----KETGIGQKKPQIFELGYGKT-VS---DVISFAKE- -NK-LLSVESALKAGEFYDVHSVTTGRGTQGVIKRFGAGIRSH--KSEKSNRK---AVL- GPEG-YGKVS-FRSLQGGKMGYHLRTEYNKQIVGIVPA------DQVQISGGLVNYGQVK NTVLLVKGSIGGTKKRLITFSAPQR-----KSAKVS-TEPM-AITYISTRSQQGGQ---- ------------------------------------------------------------ -----MSYTFAYQ----------------------------------------GPTENVA R----------------------------------------------------------- -----------AVSTNVQ-ISTKAAIMVAQFV--KHKSVSRALRDLQEVVDKQTAVPYTR FTN-GAGHKT-----K-----IGP-GKYPLKTAKAFIALIKSAQANAQDKGL-G-EELVI VSCLAQRAAKSMRY------------GR--MRGRQSKS-THIEIIV-------GEQQNGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKPIIAQK-------------RGKGSPTYTVTSHRFK- GEAKH-----FKDG-----EGL----VVDIVKCAAHTAPLALVEHEEGLL-YLTIAGEGC TVGSIIEIGA-------------SAE---LKVGNTLTLADIPEGTPIFNIESQPGDGGRF VRTSGATARLVSK-QN--N-KVIIQLPSKKQRVFHPNCRATIGVAAGGGRVDKPILKAGN AYHKARARNKLYPRVSPNSMAAHDHPFG-NTRSLRK---S-K----SRPAPKNAPPGRKV GHIRPRRTG-------RR------------------------------------------ -------------------------------MN----------------------VMKKI SVEKITINFSAGKDQNRLDKGITLIKMI-TGI-DPVKTITQ--E--RIPGWGLRPGLPIG AKLTLRGQ-PA-LDVLKRFLEARDNKLPTSCVDDFGNISFGIAEYIDIPGVKYDPKIPVM GIQISVTLKRP-GFRVLRRKLQKTSPGKNHQIRKNESMAFLTEHFGTEF-EK-------- --- >GCA_013178175 ------M-IRKR--KKITK-MRGSR--TVGGGSSKKRR-GAGHRGGRGQ-AGGHKHHWTW IVK-----YDPE--------------------------H-F--G-------KR-GFKRPR KLLK--DP--KT-----I-NLGEIQE----KLPELIK-EGIA-KK---------EKNIII LD--VTSIG--YEKVL----GRGKITEPL-HLKA---HEFSTKAEKKIEEAGG--KTE-- TI---------------------------------------------------------- ----------------------------------------------------------MI E--------------------KDFVTEGLRRTKI----------------DEYLEKEL-E RAGYGGMDIQ------VTPLGTMVVVYAERPGMVIGRGGKTVRAITQKLKNKFKLENPQV EVK-EVEVPELNPKIM----------AHKIAAMLQR--GMHFRRVAYTAMRRIMAAGAQG VEITISGK-I------------RG-------------ARAAMAKFT-------------- ----DGYIKKCGEPAIEFVKEGFATVQLKPGVLG-------------------------- ----------VYVRIM---------------PPDA----------KLPDDV--------- ------------------------E-I--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------KTPKI- -EEKA-----------------------------------------TEE----------- ---------EPEEVEEELEELEEE------------------------------------ ----VEEELEELEEEV-------------------------------------------- -----------------------------------E------EAKKE------------- ----------------------------------------------MKIKVYSLDGEPVD EIKLPKIFSE-EYRPDLIKRAVISAQTARIQPWGSDPMAGKRTSAESYGAGR-------- ----GIAMVPR-IKG------GQRAAFVPQAVGGRKAHPPK-----PYKNYHERINTKER RLAIRSAIAATANRELVKKRGHIID--KI-PEIPLVVDDELSKIKKTKETRKIF---KKL GIIDDIIRAKEG-RKIRAGKGKMRGRKYRTPKGPLIV-V-H-DDKG-------------- -----IRLGARNHPGIDIVRVENLNAELLAPGTHPGRLTVYTKSA---IEKLDK--LFKI GV---------------------------------------------------------- ---------------------------------------------MAYGPR---YRLPFR RRREGKTDYKARYKLV-DAGKLRFIVRVTNYHVITQIAKVGKIGDETLISAHSKQL-QKL GW----LANTNNISAAYLTGYLCGKKALKE-GITEAVLDIGLRPPVKGSRIFAALKGAVD AGLKVPH--SESILPD------ESRIRGEHIAEYAKSLD---ETEAKKKFSKYFE--RGL SPTRLPEHFEEIKKKI------------DEVIS--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAI-AANVTRALPVGATLHCADNTGA RELEIIAVKG--YKGVRRRLPAAGVGDMIVVSVKKGTADMRRE---VLNAVIIRQKKEYK RPDGLRVKFEDNAAVIVNPD--GSLKGSEIRGPVAKEAAT-RWPSIGSAASIIV------ ---------------------------MIG---ID-VPE-PKSK-----------C---- -N----DPNCPF------------------HGNLKVRGRILEGIVTSDKAERTVTVERSY YQFLPKYERYEKRRSKIKAHKPDCID--VKIGDTVKIAECRPLSKTKSFVVVEV------ ----------KG---------------------------------------------EK- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MARREFSYRGYRLD--------------------ELQKMPLDDVIKLF PSRQRRSLKRGF------LPRQKKLLEKVRKVKKEA-EKGGKQ--PIIRTH-CRDMI--- ------ILPEM----------------------------VGLTFGIHNG--------KDF V-----------EVKIQPEMIGHY----------------------------LGE----- ----------FAPTR-KKVEHGD------------------------------------- -------------PGMGA-TR-------------------------------SSMFVPLK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLTGTDPKKLEYVCEQIKKIAERTGVDISGPIPLPTKRLIVP TRKSPDGEGT-------ATWEKWEMRIHKRLVGI-EADERAMRQVMKVNVPDNVSIEIEL KG---------------------------------------------------------- -------MARR-----RPRSKQPRKQRKFLHN-APLHIRHKI-MSATLSKELREEY---- ---------------------NRR-SLPVRKGDKVEVMRG--DFK--GHQGKIEKVDLKN YKVYVEGATIQKVDGT-TAYFP----------IHPSNLRIIELNLE-------------- ---------DEK-RV-----------------------------------KALERKG--- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MV-R------------------------ ----AYTR---------REYIKKI-PGVKIVQYDMGNL----SGSFPL-SLSLAVKAPA- -QITHNALEAARIASNRYM-QRKAGRM-GYHLKIRVYPHHIIRENPMAT-GAGADRVQDG MRKAFGKPVSSVALVKK-NQRIITIET---N-KRNFKNAKEALRRAAMKF--PVPCKI-- ---------------------I-----IDRGEELIK------------------------ ------------------------------------------------------------ -----------------------------M-TLM-DPLANALTNIRNNELRGNTKCIISP ASKLIGQVLRTMQKEGYIGEFEYVDDGR-AGKFIVEL----------------------E GNINHCGVIKPRHAVKKDEFEKFEK--------------------RYLPARDFGIIIVTT PQGIMTHKEAKEKGIGGRLLAYVY------------------------------------ MAVAAII-----------REEIPIPDNVEVTINDK------ITVK--GPKGEVSREFD-Q H-N----IKIGK-EDDK-IILE---VK-FPR---KRDKAMLGTIKAHINNMITGVTRG-F TYKMKIVYAHFPMTVKVQ---GDK--VI-IENFLGERHPRKAKIL--GDTKVQVKGD--- ----EVHITGIDKEHVGQTMANIEQATKIKR---RDPRV----------FQDGIYLVSKG ------------------------------------------------------------ ---------------------------MARHHQPRKGSLAYSPRKRAAKETPRIKSW-P- K-VQEL---KP--LAFAGYKAGMTHITMVDNRKNSPTE--GMEITTPVTVIETPPITVMG VRAYEKT--SRG-LR---TLADVLADNLKED-----L-----ERKI-------------- ----STPG--DNY------NKDAA-----------------------IQKIEDN------ ---MD--YIQEIRILVHTNP-----RLAALPKKKPEIFECAIGGENIQ---EKLEYALEL LGE-DIKVSDVFSEGEYIDSIAVTKGKGFQGPVKRWGIRIQYG--KAARSSKGRHIGSL- GPWT-PSRTM-WTVPQAGQMGYHRRTEYNKKILKIGEA-SEAD--QINPKGGFIRYGLIK NDHILLKGSVPGPAKRLIILRKAIR-----A-PEKG-VEAP-QVTYISTASKQGT----- ------------------------------------------------------------ ----MAKIKYAYK---------------------------------------VEDEAKIA K----------------------------------------------------------- -----------ATGFRLQ-ISPKHAVEICREL--KGMKLEEAKEYLKEVIQMKRPVPFKR YNR-KVGHRR-----GLK--GWDS-GRYPVKAAKHILKVLENAEANAEYKGL-DAENLKI IHISSHRGQPIRGWIP-------RAFGR--ATPFNRPT-THIQVVL-------GEA---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRVRSQR-------------LGRGTPTYRSASHRFK- AKIRY-------KSQEETLKGK----VVDIIHDPGRTAPIAKIEYENGEE-DYILAPESI RVGEEVYHGT-------------SAP---IKPGNVLELGEIPEGTPIYNIENQPGDGGKL VRSSGTYASLITH-DI--D-KVVIELPSGELKALNPKCKATIGVVAGGGRREKPFLKAGK KYHALKAKGKKSVVVRGVAMNAVDHPHG-GGNRQHP---G-K----PTTVSKHAPPGRKV GSIAAKRTG-------KRR----------------------------------------- -------------------------------MN----------------------PMEQV RIAKATLNIGVGEGGERLARAEKLLETM-TGQ-KPVKTISK--V--TNPEFGIRKKQPIG CKVTLRGE-KA-EEIIRKFLDGIGNKLKASQFDDQGNVSMGIEEHIDMPGMKYDPDIGIF GMDLSITFEKP-GYRISRRRIQKRKVPRKHRVTREEAIKFMKEKFNVKI-IG-------- --- >GCA_007130955 ------M-IRKR--KKSRR-KRGSS--T-GRGNSKRAR-GAGNRGGRGR-AGYGKRAGHK KTMLRNK---PSLKDDK-------------------------------------GFRSTK QIKGF-HP--KS-----I-NVGELDK-----LSFKIG-NE-------------------- IN--LAKLG--YDKLL----GKGQVRNKL-IIVS---ENFSESAKVKIEKAGG--KII-- SEK-------------------------ASTEKASTEKLSE------------------- ---------------------------------------------------------MVI E--------------------RKFVKDKLRESSI----------------KEYLSGFL-D RVGFSSVDIK------KTPVGFSVIIHASKPGLVVGRGGSNIKEIQKTLESKFGLESPVV DVR-EVERPELDSKIM----------AERIGSQLKRFGASKFKAIGHKELDNILKAGAIG AEIVVSGR-V------------PS-------------KRARTWRFY-------------- ----GGYLPKCGEVAKEEVIEGFYEVKLKPGIVG-------------------------- ----------IFVRIL---------------PPGV----------KMPDVV--------- ------------------------Y-L------------L-EE-DKIF-VE--E-IEEV- ---------------------------KEEK----------------------------- --------PEKEVK-----------EEKSEKEVK-------------------------- ---------------------------EEKPE---------------KEIKEEKPEKEI- KEEKPE------------------------------------------------------ ---------KETKKKEKSKEEVKEEKP--------------------------------- -----KEEVKEEKPEK-------------------------------------------- ------------------------------------------EEKEK------------- IEGE-------------------------------------------MSKVISVQGKAKE ELKLPFQFKE-LYRPDLIRRAALAIMSHQIKPEGVSEEAGKRQSSYFSKRRD-R---YRT TYGYGQSRTPRKVMSVKGSRFVTKGASVPQAVGGRKAHPAK-----VEKVSYEKINKKEK RKAIRSAISATAIKDVVESRGHKVE--NI-KDFPIIIEENIESIKKSKDVMELL---KKL GLEKELERTKE--KKVRAGKGKSRGRKYKRKTGPLFV-V-S-KKCD-------------- -----LINSAKNLPGVDVCKVKDLNLNLLAPGTNAGRLTIWSENS---IKLLEEKKLFE- ------------------------------------------------------------ ---------------------------------------------MAEGPT---YVMKYR RRRKGLTNYNKRLKLL-KSGKPRFVVRVSNNSTICQVVEYKPDGDNTLISFDSLKL-KNY DY----KGHTGNVTAAYFAGFACGLISIKK-GIKEVILDTGLHRLTKGCRIYAALKGAVD AGLKIPH--NEKVFPQ------ERRIQGYHI----------------------------- --ED-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKGL-KAKVTRALQVGSRVKVTDNSGA KIIEIVSVKK--YKGVKGRLPKCGVGDVIMGAVKKGNPDVKHA---LLPCVIIRQKKEYR RKSGTRIKFEDNAAIVIKDLEKGEPKGTIIKGPVAREVVE-RFPLVTRISKMVV---MAQ EKT---------------KKEKTENKKSIG---IP-GVDFPKNK-----------C---- -E----DINCPF------------------HGNLKIRGRIFEGVVQSIKPSRTAIVRWER RRFFPKYERFEGRFTKISAHKPDCLN--INENDTVLIGESRPISKSKKFVVLKK------ ----------VE---------------------------------------------K-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLVEKLTFKGRTID--------------------EIKKMSLNEFMELL PSRKRRSLKRGF------TEQQKILLEKIRKAKKAL-EADKKV--GTIKTH-CRDMV--- ------ILPEM----------------------------LGLTIGVHNG--------KEF K-----------NVEITPEKMGHY----------------------------LGE----- ----------FTYNR-NRVQHSS------------------------------------- -------------PGVGA-TR-------------------------------GSTFVPVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MSKARIKLSSTDPEKINDIISQIEEIAKKTKVKYAGPIPFPTRGLKIP TRTSPDGEGR-------ELFETWEMRIHKRLIDL-DVDERALRLIMRIPVPREINVEIEI IE---------------------------------------------------------- -M--------------MIKTKKPKKQRQRIVK----RIAMKG-IGSHLSKSLIEKY---- ---------------------KIR-TAKLRVGDEVKIIRG--IFK--GKQGRVEKVIPKK EKVFIEGIEIEKQDGT-KAKVP----------VHNSNLIITSLKLD-------------- ---------DKM-RK-----------------------------------EKIERKIK-- ------------------------------------------------------------ -----KVKANEKA----------------------------------------------- --------------------------------MAKLRRASCYTKV--------------- -K-RPYTRKSRKR---EKSYVRGA-PYSKIVKFDLGNK----QADFPY-RVKLISKEDV- -QVRHNALEASRVSVNRIL-VRKAGKN-NYYFKIKTYPHHVLRENPIAA-GAGADRFQTG MSHSFGKPIGLAAQISK-GQEVMIVDV---D-KKYIDVAKTALKQAIYKC--PFKGRI-- ---------------------V-----ADKK----------------------------- ------------------------------------------------------------ --------------------------------MV-DIIAQALSQIKNAEKKGVSSCVVKP TSKTLRSILDLIKKEGYIGEFEVVDNGR-GGLIKVNL----------------------L GTINDCGAIKPRFSTSLSNYQNFEK--------------------RYLPAKNYGLLIVST TKGIMTQEEAKEKKLGGRLLAYIY------------------------------------ -----M------------EDEIKMPEGVKVRKERN-----LIFVS--GKLGEVSKKLS-H P-K----VKIDI-ENDT-VKIS---SD-TES---RKAKRLINTFLAHIRNMIKGVQEG-Y TYKLKIVYTHFPTNVKVE---GNK--II-IENFIGERSPRISKKL--PGVEVKVDKK--- ----DIIVTGIDLEAVSQTAANIERTSRIVG---KDRRI----------FQDGIYITEKG K----------------------------------------------------------- ------------------MG----H-KINKPKYPKRGSRAFVPRVRAKRIYPKIKNW-P- K-TK-----ETKLLGFAAYKAGMTEITFVDNSANSLTK--GEMICVPVTILDAPKIKVAA IRFYKKD--ERR-FKK--VSTEIWTDKFDKE-----L-----KRKI-------------- ----SVP---KKK-----LNFEEE-----------------------IKKIN-------- ---IE--NSEDITVLVYTLP------KGRANRKKPEIFEIAIGGENIN---EKFEYAKSI LGN-EISVSDVLKEGEQVDVIAVTKGKGFQSPVKRNKIKLESK--KTDRTRRG--VAAI- GPDV-PRKVS-WTVPMPGQMGFHNRYDYNKWILKVGNE-------GLNFKKGLLNYGNVK EDYIILKGSIPGSSKRLIRFRFAVN---P-N-KGIP-EKTPEKINIDGVKK--------- ------------------------------------------------------------ ----MGKTKLDSIQEK-----------------------------------KKEKLEKKA K----EK--KEEELPLEE-EKKEKE--------------KPKKKVEVKK------P---- -KVNEAK----GRGEYLP-ISPKTSVEVCRAI--TGKPVEKAKKILNESINMERPIRFYR YKK-DTPHRK-----G---KGFGA-GRFPVKVSKYVLDVLENAIANAKYLEL-DPDELYV KLAIPNRAVSKESQ---------R--GRY----------TNLEIVV-------AKKVKKV ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------KK---------------------------------------- ---------------------MPKRLRQQR-------------AGKGTTTFRAPSFRYR- YKARY--KPLNEKEIHGKIDGK----IIDIFNDTARSAPLMLVEYQTGEQ-AILQAPYGI KVGDNVEAGM-------------DAE---IKKGNVVPVGSIPSGTLIYNIELVPGDGGKL VRAAGDSARVVAH-EK--D-KVVVMLPSKEMKRLNSKCRATIGSVAGFGRKEKPIIKAGR NYHIKKARGKYWPIVAGVAMNRVSHPHG-GKRRSTQ---HTK----KKPVGRRAPPGKKV GSIAAKRTG-------RKKR---------------------------------------- -----MENN-------------------QSTKN----------------------IMQEI LIEKITLNVGVGEAGDKLEKAKVLLNRI-ADS-KVIQTYAK--K--RIPSWNLRLGLPIG VKTTLRGK-KA-EELLKRLFESVENHINPKKFDKEGNLSFGIKEYIHIPGVRYDPSLGII GLDVCVTLKRKGGFRVRRKKYKQSKVGKEHRISKEESMDFFKNKFNITI--GEKKRKVW- --- >Bin179_genes -----MK-LKKK--KKSVR-MRSRNMGTHGSGARKNKR-KSGHKGGVGM-SGSGKRADHK KTKIQKI----------------------YGHN-----Y-F--G-------KK-GFTSMG TKRD--TR--KR-----I-NIGEINLN----IEKYGK-K---------------TKEGYE VN--LP-----KYKIL----AKGDVDKKL-KIIC---FEASKSSINKIKKAGG--EII-- VKEKKKI-------------ETPKVINPKHAQKK-KKE---------------------- -----------MA----------DILKNITNRL--DNKIKEANFEGANIVLYTENENFFI EG----EGKI-----------KEIVNDIKKRIEL---RADSKILEDQETASRIIKELVPQ DAEIESILFE--------PHRSIVIIEAKRPGMVIGKQGSILGEIRKKT-----LWTPQV QRS-----PALKSKITENIRSVLYANNSYRRKFLNQIGKKIYQEWNPEKMDGWVRLTFLG GARQVGRSSMLLQTE-------NSKI--LLDCGVDVAS-SGKNKFPVFTIPEFDISQLDA VVISHAHLDHVGLLP----------YLYKMGYKGPVYMTTPTRDIASLLSLDFIGVAYKQ AEAPIFSSTDIKEMVKHSVCLNYNEVTDI--APDVRL-TFYNAGHVLGSAL--------- ----------VHLNIG-NGLH---N-LLYTGDYKYAKTRLLDPAVSTF-PRVESVITES- -----------------------TYGAKTDI----------------------------- ------LPPRKETEEKFIALV----KEALEKEGKVLLPELGLGHAQETLLRMEESMRNGE LPKVPIYIDGMVWDINAIHTAYPDFLSAKVRAQIF-QDSNPFTSEIFSRVGSPHERKNVV E-GGPCIV----------IATSGMLVGGASV------EYFREFAENENN----LMI---- ----LSCYQGPGSLGRQLQEGAKK---------------V-------------------- ---IVEEDGIKKSLNVNMKVVLFNGL-----------SPHAGRNEIL------------- ---------------SFFNNINP---------RPKRIIINHGEVSKSLDLASALYKLN-- ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????------------------MKAV-SARTTAGLNLGAKVISSDNSGA KIVRIVSVKR--GKGRKGRQGRAKVADWVKVAVKKGVPDMKGK---VFDAIVIRQKKSWR RLNGERVAFEDNAVAILKDEK-GNPKGTQIKGPVAKEVLE-RWPSVAKIASTIY------ ------------------------------------------------------------ ---------------------------------------------------KRIAIEFER MIYVRKYERYAKKKTKIHARLPKCMEKEIHKGDFIKITECRPLSKIIHFVVVEK------ ----------LK-------------------------------------------NVEEA KK------------------------------------?????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????????????????????????????????????????????-------- ------------MPKVRIKLNSTDIEKLNSVCNIIKELAKKAGIVISGPVPLPTKKLKVT TRKSPCGDGT-------ATFDRYEMRIHKRLIDL-PANEKVLHHIMRMRIPKSVNIKIEM KD---------------------------------------------------------- -MRK--IFSKH-----WKSSKQPRKQRKYRAR-APLHIKRKF-LNINLSKDLREKY---- ---------------------KMR-SICPRKKDKVKIIKG--KYK--GKTGKIIEIKIKL GKIYIEGMQVKKQEGS-KVNVP----------FRAANLQIIELDTE-------------- ---------DKK-RIK--------TTI-----------------------KSVKKETK-- -----SG----------------------------------------------------- --------ENKK------------------------------------------------ ----------------???????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????------------------------------------------------ ---------------------------MPTKRSPRKGSLQFWPRKRANKLLPSV-NW-N- A-INS----GKNLKGFICYKAGMASAYVKDNTEYSLTK--GKNIVVPITILECPPMKIFS IRFYKN-------GK---VANEILVESLDKE-----L-----KRKI-------------- ----KVP---K------------------------------------------------- ------------------------------------------------------------ ------------EKSKL------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????????????----------- -----------------------------MKEN----------------------IMREV KIEKVVLS--VGGIGDSLEKGFKLLQFI-TGK-KP--LKTKSRK--RIPTLGVKPNLEIG AVVTLR-R-DH-EELLKRLFSSIENTLSKKQISEN-NFSFGIKEYLEIPGLEYQREIGIR GFDVTVVFKRT-GRRVKLRKIKKGKIPKRQIIQKDEIIKFMEEKFQINF-K--------- --- >GCA_007117405 --------------------MRGTN--SHGWGHKKKHR-GSGHRGGFGL-AGTGARGDSQ KAGLMS--GSAKFLRKVAASKGIKVSDVKYGKS-----Y-F--G-------KD-GFKSLN NKKK--EV---------L-SISYIEH----NFDKLVE-MGVI-VK---------EKSDFI LD--TTILN--YDKIL----GKGKFSKKI-TIVC---HEISQSAKQAIEAAGG--KVV-- LTSGN-----------------------EEIQSSSEQ----------------------- -----??????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????----MKNPNK--NRVFRFN RRIRGQTDYNQRLRFL-KSNMPRLVVRKSNKNMLVQIVQYASEGDKIITSSKSRDL-SSF GF----KINSGNISAAYLTGYLVGKKALKKGFKEECIVDLGLAKVFSGSRLFAAVKGVVD AGIKVRV--SDSVFPA------EDRINGSHL----------------------------- KAKDSEKVIQSTKKAI----------EGMK------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAI-KRGNSRGLPIGAYVDVVDNSGA RVVKIISVKG--YKSVKRMLECAGVGDLVTANVVKGKPDMKHT---VVKCVIVRQKQQYK RPDGTTISFESNGAVVIKDEKTYSPKGTLIKGAIGKEVAE-RFPVVARIASIIV------ ------------------------MKTSVG---YN-LEYKPKEE-----------C---- -F----DEKCPY------------------HGKTSVRGKIFEGTVTSDAMSRTVKVEWET LVKDKKFSRYYKVKSKVSAHNPDCIK--AKKGDKVLIGETRPLSKTKHFVVLRV------ ----------IE---------------------------------------------Q-- --------------------------------------?????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????????????????????????????????????????????-------- ------------MSKARIKLVGDDIDKINSFIGEVQSITEKLGVGLIGPIPMPTKKLKIT TRRSPDGEGK-------ASFERYQMRIHKRLLDI-EINERVLRMIMKIQIPSGLNIEIKL I----------------------------------------------------------- -MKK--LWSKF-----WKSSIQSRKQRKYTFN-APLHIRHKL-MGAPLSKELRSEY---- ---------------------KIR-TVPVRTGDTVRVKAG--QFK--GKIGKITSVSLFH LKVHIEGVLIKRNDGT-EAMYP----------VNPSNLEILKLDLS-------------- ---------DKR-RHDKL--------------------------------EAIKKNGK-- ------------------------------------------------------------ --------Q--------------------------------------------------- --------------------------------MAKLRKWCAYRTI--------------- -E-RPYTRWSKVR---GKAFVKSR-PGKKVIKYDMGDLK-GGKDKFPM-CMKLVAKELG- -NVRTNGIEAGRIALLKRL-EAKMGRE-GFYFKVAVVPHHVIRENPLAA-GAGADRLSTG MKHSFGKTIATAAIIEK-GKSIYEIYC---P-TEQEAFVREALRVASKKI--SIKCSV-- ---------------------TT----TFKKKEE-------------------------- ------------------------------------------------------------ -----------------------------M-VLN-DPISDAMSKINNAVNAMYKNVTVK- KTKLILPILDVLKENNYVGSYEIIDDGR-QGLVKINL----------------------L GNINKCAAIKPRYPVAVEHLESFEK--------------------RFLPAKDFGVIILST NKGLLTQKQAKEMNIGGMLVAYCY-----------------------------------M AQINKLVK----KKWDTFEKHVDLPQEVSAVYEDS-----ILTVK--GPKGEISKKMR-Y P-F----VYIKV-DGSK-IIIG---TN-HFS---QKEKKIISTYEAHANNLVKGVTEG-F EYKLAIVYAKFPMTVGLS---GSK--FE-VKNLLGEKVPRTFEIP--SDVKVEIKGK--- ----EIVVSGIDKEKTGQVAARIEQLTKITH---LDRRV----------VQDGIFITKKP HKSYV-------???????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????????????----------- --------------------------------------------------------MREV FLEKVTVNICVGNDKQGMVKAEKLLSKL-TGK-TPVKNSAK--R--RLATWQIRPGLPIG YKVTLRDE-DA-AKFLKWVLDSKGKTLNSSSLDQTGNFSLGFQEYLELNGMKYDADIGIM GFEVMATFARS-GFRIKKRNMRPAKIPHRHKVTKEEVIKLLEKDFGVKV-K--------- --- >Bin219_genes -----MT-VNKR--KKNSR-QRGSH--THGWGAMKKHR-GSGNRGGAGK-SGSGKRSDSK K---------PSIWKN---------------KK-----Y-F--G-------KH-GFTS-- -RKH--KL--AA-----V-NVSYLEE----NLENLVS-KKLA-KQ---------GQEDFS IN--LKDIG--FKKLL----GSGKITKKL-IITC---QAASARAVKSIESKGG--KVI-- L---------------------------PTPK---------------------------- ----------------------------------------------------------MK SE---------------IRVVNIVVSTSLQHDIP----------------LEKMAATL-S NTEYNPEQFPGLVIRIKEPKTSALIFSS---GKVVCTGARSMDKVNESIK---------- ----------------------------KIIKSLEKI-GIKIKIKPEVKIQNIVASGTVG MDLNLNTLAMKLRNTEYEPEQFPGLVYKLVDG----NAKATFLLFS-------------- ----NGKVVCTGTKSEKEVRSAL------------------------------------- ------------------------------------------------QKL--------- --------------------------I--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --ANLKTVKKK------------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MNIELFNLEKNSEG KVELPAQFDE-AISTSLIARAAITIQLNKRQPYGTDPKAGARSSAQVSRRRR-K---YRG SYGKGISRVPRKILSRSGMQFNWQGAVAPGTVKGRRAHPPK-----AYGIWLKKINKKEN SKAIRSALAAAMAKDFVKNRGHIMP--E---GYPFVVNDSLTSIDKTKLVKQTL---EKL GFKPELSRTTK--KTIKAGRGKTRGRKYSRKVGPLIV-V-A-DKCP-------------- -----LQKSAANIPGVDVVLANELNADILAPGTIPGRLTLFTASS---INKIKSEKLFM- ------------------------------------------------------------ ----------------------------------------------------------FT RKRKHVTNYRSRLKLI-LSGKERLVIRKTSRAIIVQLTKFDGKGDLVVTSASSSQL-KKH GW----QFGTKNIPAAYLTGLLAGKLALAK-KVKQAVLDVGMSKPSANGRVYAALKGVVD AGIEVPL--SEDILPS------EERIFGSHISSYMNSTK-SAN-----QFSSYKK--ANL SAEKIKELFNTVKANI------------SGEKK--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????????????????????????????????????????????-------- ------------MQKARIKLVSTDIEKINQVSTSIIDIAEKTGVELSGPIPLPSKKLKIT TRKCPCGDGK-------ASWDRYEMRVHKRLIDL-ATDERALRLVMRVPLPKGLNIEIEM VDN----MEQQT--------------------------------------------TQIF AVRT--TANREEQVMDFIGSNAKKKKLEVYSLVHPHGMRGYIFLEAKARLDAEQAAFKVP YARGVLPNQIDYAEIEHMLEPAKKVEMNIQKNDIVEIIAG--PFK--REQAKISRIDKTK EEVVVELLEA-------AVPIP--------ITIRMDSVKVIRRVGD-------------- ---------E------------------------------------------VKEEKD-- ------------------------------------------------------------ --------E--------------------------------------------------- --------------------------------MAKMRRSRAYRRI--------------- -E-RPYTRISKFK---KKSFIRVT-PSRKITRFNMGDE----KTR-KY-SLDLVSKKSI- -QIRQEAIESARMTSLRLL-EKSI-AS-DFFFRIRKYPHHILRENPLAA-GAGADRVSTG MKQSFGKPIGVALQLKE-GERLFSVSV---N-EAGIDIARKALQRAIKKL--PSPFFI-- ---------------------V-----ITRNKTK-------------------------- -------------------------------------------????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????------------------------------------------MIIETA ------------QIAVAILG------KMPTVRRPRHGSLQYWPRKHAKRMYPRIRHY-A- P-LS-----EPKLAGFAGYKAGMTHVFIADNRAHSMTK--GKSIVFPVTVLECPPLKVAS VRFYKSS--PYG-LS---VAAEIFSSS-DKN-----L-----AKKL-------------- ----NLP---K--------K-PKD-----------------------LAEVEKK------ ---LG--EYVDVRVNVYTQP-----RLAGINKKRPEIFEVALGGKDVN---EKFNHAKSI LGK-EISVKDVFKEGQQLDIFAVSKSKGTQGPVKRFGIGLRSH--KSEKGRRG--PANV- GPW--KGNRS-WTVAHAGRMGFHNRLEKNKWLLKIGD---KPE--EVNVKGGFIKYGVVK SSYLLLKGSVPGATKRLIRLVNSYH---P-N-HKLP-EQAP-SIEIVSLKSPQG------ ---------------------------------------------------????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????????????????????????-- ---------------------MGKNLTSQK-------------RGKGSSVYKSGSFRYV- GTVKH--HPYSEKEKKDKVTGI----VTDIVHSSGHYSPVAKVNYEGKET--LAIAPFGI RVGDEISSGT-------------NAE---VKDGNVLPLSS-------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------??????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??? >GCA_013375405 ---------MNPIRTTDPR-RRRLI-------------------------RALDRTKR-- -----------RIWKN------------------------V----------SG-FLQKSR TNRI------------IV-NLGKINVF----------------SE---------GKDIIL IP----------GKVL----SSGELTHHV-TVAA---FAFSKKARKKILKAGG--ESI-I IEDLLKR------------------------NPTGSKVKLLT------------------ -----MLIESVLS----------DLKNLIIQNLPENVNITAIEFEGPEIALYSKNPKILL ES----RDIV-----------KEIAKKMRKRLVI---RSDPSVRLPQEETKKIIMELCPE EAGITAISFD--------PNVGEVIIEAKKPGLVIGRGGLTLKQITQSV-----LWRPSV IRT-----PPLTSDMVLKLRHAIKQDSEQRKKILKKIGMRIHRPIFLK--DEYIRLTALG GFREVGRSCILIQTP-------KSNV--ILDCGINVGTSSTSNVYPYLNINDFNIEDLDA VIISHAHLDHQGLVP----------FLFKYGYGGPIYCTKPTRNLMTLLQLDYLDVSERE GRLLPYSQKDVKKAVLHNVPLSYGEVTDI--APDIRL-TLHNAGHILGSSI--------- ----------VHLHIG-DGLY---N-LAFTGDFKYAKTRLLEPATTSF-PRLETLILES- -----------------------TYGAAKDT----------------------------- ------MPARRESEKILVNVI----NRTLRENGKVLIPVLAVGRAQELLIVIEEYMRRGL IDEVPVYIDGLISEATAIHTTHPEYLSRDLREMIFHQGMNPFLSEYFVQVDNVSVRSDII E-GDPCII----------MATSGMLNGGPSV------EYFRRLARGVEN----SLI---- ----FVSYQVEGTLGRRIQKGWRE---------------I-------------------- --PMRVNHNRTEAVHVKMNIITNEGF-----------SGHSSRQQII------------- ---------------NYIRKVEP---------KPERIITCHGENSKCTGLASSIHKLLRI ETRAPQNLESIRLK------------------------------MAQKVNIFSLDGKAKK TITLPEVFQT-PFRPDIINRAVVAMQTHRYQPKGVNKKAGQRNTAESLGTGR-------- ----GISRVPR-IKG-GGTPAAHQGGFAPGIRGGRQAHPPK-----AEKNIRKEINKKER ILAIRSAIAATANKTKVSERGHVID--EL-VEIPTVLEDDIEKLQKTSEVREVF---ESI GAMGDIMRA-SV-KKIRAGKGKMRGRKYKRKKSVLIV-V-G-KDNG-------------- -----IFQAARNFTGVDICEVRNLNAELLAPGGHCGRLTIWSESA---ITQVSS--LFS- ------------------------------------------------------------ -----------------------------------------??????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????-MGKRRVR-----KK---GAHL-LPKISRGLPTNAKILCSDNSGG KILKVIAVIG--YKGRLNRIPSAGVGSMVVTSVVKGTPEMRRQ---IVRAIIIRQRKPYR RADGRWIQFEDNAAVITSPL--GDPKGSEIRGAVAKEAAE-RWPRLASVASMVV------ ------------------------MVRDIG---FE-VEA-PRKE-----------C---- -E----DPHCPF------------------HGSLPLRGRIFNGIVIKKKMSDACVVRRDF LRYIQKYNRYERRHSNINCHIPPCIE--INIGDAVKMAECRPISKTISFTIVEL------ ----------IE--------------------------------------------SE-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MVKKFTFRGYTLE--------------------ELQNLPMDEFIKLL PSRQRRSMLRGL------PPRQKKLLENLRRARRAL-KKGKKV--I-IRTH-ARDMV--- ------ITPEM----------------------------VGLTIATHNG--------RIF I-----------EVAITPEHIGHY----------------------------LGE----- ----------FAPTH-KRVTHGN------------------------------------- -------------PGIGA-TR-------------------------------SSQYIPLK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIRLASTDSKKLKEICDQVKRIVERTGIHISGPIPLPTKKLRVP VRKSPCGEGT-------ATWDRWEMRIHKRLIDI-DADERTMRQVMRIRVPDDVYIEIEL K------MAEISKCSKYGCLI-----------------------------------LCNL GLKM--Q-TNK-----KNKTKSPRKQRKRFYN-QPNHKRNRL-FTAKLHDDIQSEY---- ---------------------FIK-SLTICKGDTVLVVRG--EFR--DMEGKVAKIDRQK AQIFIEGASIEKSSGT-TFDIP----------IHPSNVVLTKIEVK-------------- ---------KDKWRK-----------------------------------KIIDRKSKIM ------------------------------------------------------------ --------EED------------------------------------------------- --------------------------------MP-RRPWSSYHNI--------------- -KGKPYVKRWKKTKKGRREYVHGV-PDPKIRMFSMGT-----NKDYEY-RVILLSDANA- -QISHLALEAARIAANRQL-RNKVGRE-DYFLRILVYPHHVVREHRMMA-FAGADRLQDG MRKAFGKPFATAARVKR-DQKLISVKV---N-KKHLPIAQHALSGARMKF--PQHCHI-- ---------------------E-----VVKLKQKEKPPL-------------SEEASSVS -------------------------------------------????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????------------------------------------------------ ------------------MG-------HRKHSAPRHGSLAYHPRKRASNFTGRWRSW-G- N-ISYA---EPTILGFAAYKAGMTHVILVEDKKTSPYY--GHEVSRAATVLDTPPTIVCA IRAYRFT--NSA-LK---VLGEVWAGELSED-----L-----RRKF-------------- ----PTP---KEY------SMDKA-----------------------LLELEKQ------ ---IK--NATELRLILHTQP-----RLTSLSKKKPDIFESKIEGGSIT---DQWKFAKEL LGN-ELKVSSTLKEGDFIDVSAVTKGKGFQGPMKKFGIKKLPR--KSRKTVRG--VGSI- GPWT-PGRTM-WTIARSGQMGFHQRVEYNKRILKIGI---DPK--EIIPAGGFLNYGLIR GDYLLVLGSIPGTRKRMIRLRKAIR---P-P-KNVP-DTPP-DLVYIS------------ ------------------------------------------------------------ ---MCPNFGYSIT---------------------------------------GLDPDRTA V----------------------------------------------------------- -----------ASGRDLR-CSPKHAREVCNTI--KGMMIEDAKLLLDTVILHKQAIPFKR HNK-KQAHRK-----GLDKFRWPA-GRYPVKAAHSVLVVLENAENNAEFKGL-DLDRVRI IHAATSRGRKIKKYIP-------RAFGR--STPYFKTL-THVEIAL-------EEE---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRIKVQR-------------RGRGSPTFRATKKRKR- GTVKHP-T-LS-THKDKPLEGE----IIDLEHERGRSAPLARIQYENGKK-SYMIAPEGI SIGEEIRIG--------------SPE---IKIGNTLPLKDIPEGTSIFNIESQPGDGGKF VRAGGTYATVVTR-DP--S-KVIVKLPSGKSKQCNPECRASIGVVAGGGRTEKPFVKAGN KFHHCRAKNQKWPVNRGVAMIAASHPHG-GGQKQHI---GKK----SSCVSRNAPPGRKV GLIAARRTG-------RKKK---------------------------------------- -------------------------------MDEEVISYFSSEDKTQILEMWKRHTMRQL KIAKVVVHMGVGASGERLEKGIKVLESL-TNQ-KPIKLLAR--K--TIRDFGIRKGEPIT AKVTLRGE-KA-IEFLQRALTVVENKIKYSSIDNNGNISFGITEHIELPETTYEPSLGIF GLDVCINVKHP-GYRISERRKYKRKVPKKHRVSKLETMIFLNTQLGVEI-VKEYVISYY- --- >Bin69_genes --------MIKR--KKNTR-QRGSH--THGWGSKKKHR-GAGNRGGRGN-AGSGKRGDAK K---------PSFWKD---------------KS-----Y-Y--K-------SK-GFKS-- -LRK--AL--KT-----L-NISDLNK----FED-------------------------TK ID--LNKEG--FNKLL----SQGTPNQKY-EIIV---SYASKTAIEKITKAGG--KVS-- GLVKPKPKKEKKEVSETQGSKAPGA-PKENLSSEPAKVVEEEVELEVSEEETVKEEKEDS ETKEE-----------------------------------------------------MI E--------------------RKFVADNIKEFQI----------------KEFVKKNL-G RVGLSDVKLQ------KTPLGEKIIIAASRPGLVVGRAGANITKITNQLKSAFKLENPQI EIE-EVKEIGLDANII----------GELIAGSLERYGSARFKGIGHKAMSDVVGAGALG VEIIISGK-I------------PS-------------SRAKSWRFY-------------- ----KGYLKKCGDVSVEGVLKAYAIAKLKTGVVG-------------------------- ----------IRVSIM---------------PSTL----------KLPDKI--------- ------------------------T-L------------I-SEVQEV--IE--EVTGE-- ---------------------------EAEE----------------------------- --------IQEEIK-----------EEVEEKE---------------------------- ---------------------------SKSKE-----------------------KKEIK TEKKEKP----------------------------------------------------- ------------VKKKIAKKTPTK------------------------------------ -----RAEKKEEVKKKTRKTKKT------------------------------------- --------------------------------AT--------RKKK-------------- ----------------------------------------------MKLKILNLTKTESG SVNLPKQFYE-PVRTDLIKRSFLSIQSNKRQPYGADPRAGKRASAELSRRRR-K---YRG SYGLGISRVPRKILSRRGTRMNWVGAVAPGTVGGRRAHPPK-----AEKKWPKRINKKER RKAIRSAMAATLDVELVKNKGHLPP--Q---NYPFIIDDKIDEITQTKKLIDTL---EKL GFKEEIKRAKE--K---------------ESRGVLL--V-S-SNEN-------------- -----LKKTSSNLPGFEAEKVSNLNTELLAPGGVPGRITLFTKSA---IKELDKKQFFTD DFK-AEKEVK-------------------EEKPVKKEESKQLVKTKPT---------KSI KTVKKITTNKTKKK--------------------------------MNRTK---SRIQFH RKKSGKTNYKKRLELL-KSRKDRLVIRKTNKYLIIQMVKYEAKGDRVVVSTNSKEL-VKL GW----KNSCKNIPACYLTGLLLGKKAKEK-GLKEAILDIGLQTPIKGSKLFAALKGLID LGLNVPS--SEQIFPV------NERIQGKHI----------------------------- -SDKIVKDFELTKNKI------------MK------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKPV-KARITKGLNVGSHVETCDNSGA KMLKIISVKG--SKTVKGRLPAAGISHLVQASVKKGKPEMRKQ---VVFAVIVRQKKEYR RPSGERIKFEDNAAVVLKDDK-GNPKGTIFKGPIAKEACD-RWPGIAKIASIIV---MNK E------------------QKSKKSSKG-------------------------------- --------------------------------NVRLRGRVFEGKVISDKMHKTVTVEWNR KKFVPKYERYEKRRSRVKAHNPEEIN--AKEGDIVKIMETRPLSKTKHFIVIEV------ ----------KK---------------------------------------------TEE S------------------------KENETS----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKE-FFYRGRTLN--------------------ELKELSLNELSELL PARQRRKIKRGL------TEEEKKLVIKLEKKDN-------------VKTH-LRDMV--- ------VLPTM----------------------------VGKTIRVHNG--------KDF Q-----------PVIIQEEMIGHI----------------------------IGE----- ----------FILTR-KRTEHSA------------------------------------- -------------PGVGA-TR-------------------------------SSASVSVR ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLASTDIHKINETCQYIKNVADKTGVVMRGPIPLPTKKLRVT TRKSPCGDGT-------ATWDRYEMRVHKRLIDM-GLDERALRLVMRVPIPPGLNIEIEM IDA--------------------------------------------------------- -MKS--TFSKT-----WVRSKQPRKQRKYVAK-APLHIKGKL-LGVHLSKELKKKH---- ---------------------GKR-SIRLRVGDKVKLLRG--SHK--GEEQKVERINIKN QKVYLEKIEFTKKDGS-KSTRP----------FHPSNMVITSLNTD-------------- ---------DKK-RM-----------------------------------QKLKGET--- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MVKLRRAVAYRRI--------------- -E-RPYTRKSKYR---SQQFVRAV-PHNKVVKFEMGDL----KKKFDY-VVSLKSGADI- -QIRHNALESGRLTSNRLL-EATCGKT-GYKLKVLVYPHHVLRENPLAA-GAGADRMSTG MKKSFGKPVGLAAQISK-GQIMYQAFV---D-EEFLETGKKAIDRIKHKL--PCSCSV-- ---------------------V-----VEKNA---------------------------- ------------------------------------------------------------ -----------------------------M-SLN-NPLANVLSFIQNYEKLGKNEVITKD NSKLIKKVLEIMQREGYVGSYEEIRDSK-GNSLKINL----------------------L GNINKTNVIRPQFQIKMSEFEKFEK--------------------RYLPAKDFGIIILST NEGLLTHKEAKEKNIGGKLIAYCY------------------------------------ MTNKGF------------QDEIELPEGCQVSFENK-----TIKIH--GEKGEADRKLF-D P-A----VAFKS-EGNK-IIIT---TR-NNN---KRNKKMLNTYKAHIKNLIKGATES-H IYKLKICSGHFPMTVGVK---DNL--FE-IKNFIGEKVPRQLEIL--EGTEVKVDGA--- ----EVIVKSVNKEKAGQMAASIEQLTRRPG---FDKRI----------FQDGIYLTEKD GKPIE------------------------------------------------------- ---------------------------MPTIKKPRKGSMQFWPRKRAKKHYARVRSW-P- E-VK-----DVKPLAFIGYKVGMTHKIAINENKNSHLK--NEEVSVPVTIVECAPIRVFS ARFYKTN--EGE-LQ---VEKEIFFKT-EKN-----V-----KRKT-------------- ----KVS---K--------ENSKD-----------------------LEKIN-------- ---PE--EYDKITINIYSQP-----EKTGVGKNKPEIVEIGLGGSN-Q---DKFEFIKQN SDK-EITVDTVFSENQFVDIHAITKGQGYQGPVKRFGIGLKSH--KSEKGRRA--PGSL- GPWNRQQHIM-WRIAHAGQTGFFQRVDYNKQILEISN---EPE--KEGK--NFHKYGNIK STYLLIHGSIPGPKKRTIIMTQPIR--EK-N-KKHQL-----SIQ--------------- ------------------------------------------------------------ -----MTENVNQE----------------------------------------KGSENTA R----------------------------------------------------------- -----------ASLKEIP-ISAKHSIEICSRL--KNKTVEEAKKYLEAVKNMEQPVKFTR FTE-GAGHKR-----K-----IGS-GKFPVKAAENILKAVKSAESNAQIKGF-SR-DLKI ISISANRASRPWHY------------GR--QRRIKMKR-THIEVIV-------KEFEQK- ------------------------------------------------------------ ------------KKQPVKTESKPE----------VEEK---------------------- -------------------------------QVQKESQEKSL-------KEVK------- ------------------EKKEEK------------------------------------ ---------------------MGKRLTQQK-------------RGKGSPTYKAPSFKFV- GNASQ-----IQQE-----KGR----VVDIINSTGHTAPLLKVEYQDKQT-NLVIAADGI RVGDLLERGD-------------KAD---LKRGNALPLGKIPEGVSVFNIELIPGDGGRA VRTSGTSARIVSK-SR--N-KATVKLPSGKQKAFDLKCVASIGVVAGSGRTDKPYLKAGI KKKVMAARGKYWPIVSGASMNAVDHPLG-GARSSRK---G-R----PTIAPKNAPPGRKV GMIRPRQTG-------RNK----------------------------------------- --------------------------------------------------------MKEI KIEKVTLNIGAGKDQIKLKKSVELLKHL-TGI-NPVKTITQ--K--RIAGWGLRPGLPIG CKLTLRKE-KA-KTMLVRLLQAKENKLLPSSLDDSGNISFGIPEYIDIPEAKYDPEIGIM GLQVSVTLERP-GFRIKRRKVMKRRIPISHKISKEDAAEYLKKEFKIKI--GEEE----- --- >GCA_012729535 -----MP-VNKR--SK----YRGSR--TCGGGTHKNRR-GAGNRGGRGR-GGSRDHKFVR GVV-----HANW--------------------------V-Y--G-------CC-GFKHHH QSAL--TG--DV-----L-DIGQIDQ----IIPSLLE-QGMA-TR---------DGESVV LN--AADIG--IAKVL----GGGQVTCKM-NITA---EAFSQSAIEKIEAKGG--HAL-- LS---------------------------------------------------------- ---------------------------------------------------------MAV E--------------------RKFVADGVRKVRV----------------ERHLGHEL-K RAGYGGMDLI------RTPLGTQVTIFAEKPGIVIGKGGKVVRGLTQDLATTYGVESPQI EVQ-QVDNPNLNAQIM----------AERLASALER--GWYFRKAGSSTLRRIMDSGALG CEVVISGK-L------------TG-------------ARGRVQKFV-------------- ----EGYIKHSGDPVNTLVDKGYAVAIKKLGVIG-------------------------- ----------VQVRLI---------------PPGA----------LLPDHF--------- ------------------------E-V-------------TAEVTKKQ--RNMAHI---- ------------------------------------------------------------ ----------TRIP-----------EEYDEENLDLD------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AIINESDDFMEEE----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MKAQVLTLTGTVAH EIDLPSIFSS-EYRPDLIKKAVIAQQSRRYQPHGAYVYAGITASAVGWGSGR-------- ----GASHVPR-LKN------SSRAAKVPQAKGGREAHPPK-----VEKVLVREINQKEK RKALQSAIAATISSDLVRSRGHVFN--G---SLPYVLSGEFETLKKTKEVISAL---RAI GVYGDIERAERS-RKVRAGRGKLRGRRYKQRKSLLIV-T-C-NEN--------------- ------LLAARNLAGVDVCRVDNLNVELLAPGTHAARLTLWTEDA---VKKLGGEQ---- ------------------------------------------------------------ ---------------------------------------------MATGPR---YFVSFR RRREGKTNYHARMRLV-VATRPRMVVRKTNRHIICQIVTAHMEGDKTHVAVNSSEL-RKF GY----EGSLNNTPAAYLTGILLGVRAINA-GQEGAVLDIGLNRATRGARVFAALKGAVE AGFDIPH--NEEILPA------DERCKGEHIAAYAPD----------------------- RAGSLPANVAATVDAI------------MGELN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKGL-GIKVPRAVSTGTKMICADNTGA RVVQVVSVFG--YHGVRRRQPKLGLADIATVSVKKGTPDMRRK---LVRAVVIRQKKEIR RPSGLRLSFEDNAVVVVDDK--NEPRGTEIKGPVAREVAI-RYPRIGSMATIIV------ ------------------------MARDIG---LN-VPV-PDKD-----------C---- -S----DVNCPF------------------HGTLPVRGQVITGKVVSDKMTGSIVVQRDY LHFVRKYQRYEKRSSKIHAHNPPCLG--ARVGDMVSIAECRPISKTKTYVVVEV------ ----------NR---------------------------------------------S-- ------------------------------------------------------------ ------------------MAKKVQK----------------------------------- ------------------------------------------------------------ ---------KLPRRKEEFTYHGYKID--------------------ELREMSLQDLLPVM PSYARRKVNRGW------TIGEEKLLSDIRSDNTR------------IRTH-QRDMI--- ------VLPEM----------------------------IGKELEIYNG--------KEF I-----------RVELQPESVFHY----------------------------LGE----- ----------FALTR-RRVTHGS------------------------------------- -------------AGIGA-TR-------------------------------SSKFVPLK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIRLTGTDYQKVEEVCQKIKEIAERTGVNLAGPIPLPTRKLVVP IRKSPDGEGT-------ATWDRWQMRVHKRLIDL-DADERALRQLMRTQVPKDIGIEIVL ES---------------------------------------------------------- ---------MV-----RVISSQPRKQRKARYN-APHHMRGSL-LHAALSKELQGKY---- ---------------------KRR-SIRVIKGDTVKVIRG--DHA--GSTGLVDFVITKS ARIVVDGVSVKKADGT-EVPRP----------VDPSNVVITELNLD-------------- ---------DKL-RE-----------------------------------QKLSGE---- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MV-RKPNSMYRNL--------------- AK-KAYTR---------KEYMGGI-PAVKVVHFDMGNL----TSEFPM-EVSLVVDESC- -QIRHSALEAARMSINRKL-NKELGRM-NYHLKLRTYPHHVLRENKQAT-GAGADRVSQG MRLAFGKAVGTAARVQQ-NQKIYSVFS---N-PAGIEKIKDALRHGGHKL--PSPTHLE- IQ-------------------M-----KQES----------------------------- ------------------------------------------------------------ -----------------------------M-ARL-NIVADAMSTLKNASDTGRSVCIVQP AGRLIGELLRIMKEAGYIREYTRIEDGR-GGQYKVVM----------------------S GLINKCGCISPRYSVSLSEMEYWEQ--------------------LYLPSKSIGLLMIST SKGVMGHHDARRNGVGGELLGYVY------------------------------------ ---MIV------------ERTVSIPAGVTVALDGT-----VLKVK--GPKGDLMRDMW-Y P-G----IGITV-EAED-VRFT---TE-SQK---KAVTSMVGTLASHCTNMCAGVSRG-Y VYTMKIVYSHFPIQIKVQ---GDR--LE-IVNFLGEKHPRYARIL--PGTTVKVGND--- ----EVTVTGIDKEIVGSTAANIERATRIRD---RDPRV----------FQDGIYIISRS EQ---------------------------------------------------------- ---------------------------MSNIHRPRMGSLAYSPRKRAKSPVPKYHAW-P- A-YQG----EPALQGFAGYKVGMTHVVMVDDHANSPNE--GKDIMVPVTVIEVPDMRVAA IRVYYHD--TYG-NH---VLTEIWADSFDKE-----L-----NRRL-------------- ----NLP---KNY------KREEA-----------------------EKKIREA------ ---LEAGKIVDVFALTYTRPS----VLTGVPKKVPDLMETRIDGGSMT---ERFEYGLTI LGK-DFSIQSLFKVGQYTDVTAITKGKGTQGPVKRWGVHLRKR--KHSRGKKERHVGTL- GPWT-PHHVR-WQVPMMGQMGYHQRTEFNKRLIKIGE---DGT--EITPEGGFINYGLVR ARYVLIKGSVPGPSKRLVRIRHAMR---L-G-EHK--IREP-TIGFVSLESKQG------ ------------------------------------------------------------ ----MTRFDYSNQ----------------------------------------VTGKDIA R----------------------------------------------------------- -----------GRVNEAP-VSPKHAIEIARFI--NGMKLDDASAYLQSVVALEKPIPFKR FNR-NVPHRK-----GLV--GWDA-GRYPQKASRVYLRLLNNVRKNAEYNGL-EGEHLRI VHVCANRGIRRRSFMP-------RAMGR--ATPKDRQT-VNIELVV-------REQEA-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGHRITTQS-------------RGHGSPTYRAPSHRYK- AALRH-----L-GRSGETVSYK----IMDIEHDPARHTPIALVDVPDGEN-AYVLVTEGM GIGDVLTWGA-------------EAE---IKNGNTLPLQAIPTGSSVCNIEANPNDGGRF VRAGGVQATVTDK-ME--G-RVAVKMPSGSTKWFNGQCRATIGIVAGGGRNEKPFVKAGK KYHKMKNTASNWPRVRGMAMNVIDHPFG-GGGHQHP---G-R----PKTVSRGTSPGRKV GHIAARRTG-------RR------------------------------------------ -------------------------------MN----------------------PNRAV AVDKVVVHMGVGEAGDKLVNAERIISEI-TGN-SPVRSVAK--Q--TLPAFGIRKGSPMS CRVTLRGS-TA-TKFLETSIRIIENKINSRSFDKQGNFSFGIEEHTDYPGQSYDPKVGIF GLDVTVVLRRN-GVRIARRHIQQKKLPLKQLVTVDDAKLFLKDRYNVEV-Q--------- --- >GCF_018432605 -----MP-VNKR--SK----YRGSR--TCGGGTHKNRR-GAGNRGGRGR-AGQRDHRFSH FYL-----KGEI--------------------------S-N--G-------KH-GF--IN KTSV--PV--SA-----L-DVGEIDQ----MADALLR-EGLA-SQ---------EGDLIT LD--ATEIG--IEKVL----GGGRVTHKL-SISA---RGFSERARAKIEEMGG--QAT-- TV---------------------------------------------------------- ---------------------------------------------------------MAI E--------------------KKFIAEGVRNVRV----------------EKFLTKEL-K RAGYGGMDIT------RTPLGTQVTIFAEKPGIVIGKGGKQVRQLTQDLATVYEIESPQV EVQ-QVTNPNFNAQIM----------AERLANALER--GWYFRKAGQSTIRRIMESGALG CEVVVAGK-L------------TG-------------ARSRTQKFT-------------- ----EGYVKHCGEPSETIVEKGYAIAIKKLGTIG-------------------------- ----------VQVKIV---------------PPDA----------RLPDAF--------- ------------------------D-V-------------LEPAPKKA-PAEPIEA---- ------------------------------------------------------------ ----------EEVG-----------EDVFE------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------EEFEETSGEEY---------------------------------- ----VEEER--------------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MKAQVRTLTGEIAH EIDLPEIFTE-EYRPDLIKRAVLALQSTRFQPHGTNPYAGMRTSAESWGSGR-------- ----GVAQVPR-LKN------GSRVARVPQATGGRAAHPPK-----VEKILVKEINRKEK QKALRSAVAASTYLDLVRERGHLFE--G---DLPLVFEDRFEEITRTGDVISAL---SAL GVYADVERAKSS-KKVRAGRGTMRGRRYKQRKSVLIV-T-G-SEP--------------- ------LRAARNLAGVDAVTVSQLNTELLAPGTQAGRLTIWTESA---IRRLEEFS---- ------------------------------------------------------------ ---------------------------------------------MATGPR---YFVPFR RRHEGKTDYYKRMSLL-SSGTPRMVVRRTNRQIIVQLVVPEIEGDRTLVAAYSAEL-AGY GY----EGTTASTPAAYLTGMLFAVKALNA-GYEDAILDIGLARAKPGARVFAALKGAVD AGLDVPY--GESILPD------EERLKGAHIAGYAPE----------------------- RAGDLVANVEAVALAI------------KKELV--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAM-QSTIPRALATGSRMVCSDNTGA RLVEVISVDG--YHGVRRRQPCMGVGDVATVSVKKGTPDMRRK---LEKAVVIRQKKEIR RPNGIRLSFEDNAMVLINER--GEPKGTEIKGAVPREIAE-RFPKIASMATIIV------ ------------------------MARNIG---LD-VPI-PEAE-----------C---- -E----DANCPF------------------HGTLPVRGQVITGKVVSDRMNGTVVVEREF LHYVKKYKRYEKRRSRYHAHSTPCIN--AGVGDVVRIAECRPLSKTKNFVVVEV------ ----------MK---------------------------------------------E-- ------------------------------------------------------------ ------------------MAKKTQK----------------------------------- ------------------------------------------------------------ ---------RMPRRREEFTYRGYSVE--------------------DLKQMALSELLPLM PARARRKFDRGL------SREHEKFLADLRSGDAK------------IRTH-LRDMI--- ------VMPEM----------------------------VGRTIEIHNG--------KEF Q-----------AVEIQPEAVFHY----------------------------LGE----- ----------FALTR-RRVSHGS------------------------------------- -------------AGIGA-TR-------------------------------SSKYVPLK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIRLSGTDFEKIEMVCDRIKEIAERTGVNLAGPIPLPTKKLVVP TRKSPDGEGT-------ATWDRWQMRVHKRLIDI-DADERALRQLMRIQVPKDIGIEIVL ES---------------------------------------------------------- ---------MV-----RIVSKQPRKQRKARYN-APNHTRGRF-LSASLSPELRGKY---- ---------------------DAR-RARVVKGDTVKVLRG--DFA--GDEGVVDAVDMKM CRLIVHGVMVTKADGT-EVPRP----------VDPSNVQITKLNLK-------------- ---------DKL-RE-----------------------------------ERLGGGA--- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MV-RKPAKMYRNL--------------- AK-KAYTR---------REYMGGV-PGSKIVQFDMGNL----TENYPV-ELSIVADETC- -QIRHTALEAARIGINRQL-VKEVGRA-NFHLKIRTYPHHVLRENKQAT-GAGADRVSEG MRLAFGKAVGTAARVEK-GQKVFSVWT---S-PQHVEKAKASLKRGIYKL--PTPARI-- ---------------------V-----EERAPTA-------------------------- ------------------------------------------------------------ -----------------------------M-ARL-NPIADAMSTIKNAGDAGKNEVIVEP ASKLLGAMLRVMQENGFIGGFEFIDDGR-GGQFRVQL----------------------S GTINKCGAITPRFPVAMADMEYWES--------------------QYLPAKNFGILIVST SKGVLSHAQARSEGIGGQLLGYVY------------------------------------ ---MGI------------TRQVEIPPGVDVTLEGS-----VLTVS--GPKGTLVRDMR-F P-Q----IDLTV-GDGE-VVVS---TA-SDK---KRILAMTGTLEAHVKNMTRGVVDG-Y EYRMKVVYSHFPIQLKLQ---GNR--LE-INNFLGEKQSRTAKII--EGVTVKIGND--- ----EVTLTGIDKEKVGNTAANIEHATRITK---RDPRV----------FQDGIYITERA ------------------------------------------------------------ ---------------------------MPKINRPRRGSLAYSPRKRAKSPVPRYGSW-P- E-YTG----APAVQGFAGYKVGMTHVIMVDDHKSSPTE--GKDVMVPVTVVEVPPMRVAG VRAYSED--TYG-KH---ALTEAWTTGLDEE-----L-----SRRI-------------- ----NVP---KNH------DTAAA-----------------------LDAIRNA------ ---VGEGRVAELYALAYTRPM----ELTGVPKKVPDLMEMRIAGGSLD---DQIAYAADI LGK-EITISGNLEVGEYVDVTAVTTGKGTEGPVKRWGVQVRKR--KHSRGGKKRHIGNL- GPWH-PHHVR-WQVPQMGQMGYQQRTEFNKRILKIGT---DGD--DITPAGGFLHYGLVR GPYVLIKGSVPGPNKRLVRIRSAIR---Q-G-EHT--VRTP-TISFVSVQSQQG------ ------------------------------------------------------------ ----MARTDYSAK----------------------------------------IGGENVA R----------------------------------------------------------- -----------AKANELP-VSPKHSIEIARFI--RKMTTTEAKAYLADVVELKKAIPFKR FNR-NVAHKR-----GLS--KWPA-GRYPVKAAEAYIRLLESVEKNAEYIGL-DVENLRI DHVAANTGRGLRAFFP-------RAMGR--ATPKRRET-VNIEIVV-------TEVA--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MAHRIIAQS-------------RGKGGPSYRAPSHRYK- AELRH-----V-GKNDALVSGS----VVDIEHDPARHAPIALARLESGEK-VYVLATEGL GVGDAVSWGT-------------GGA---VKNGNTLPLREIPVGAYVCNIEARPNDGGKF VRSSGVQALVIGK-AED-G-RVGVRMPSGKNKWFNGACMATVGIVAGGGRGEKPFVKAGK KHFHVRSSSERWPRVKGVCMNVIDHPFG-GGGHQHC---G-R----PKTVSRGTSPGRKV GHIAARRTG-------KWKK---------------------------------------- -------------------------------MS----------------------AMKDV YIDKVVVHMGVGESGERLVKAEDLVKQI-TGQ-KPVRTIAK--R--TQPAFGIRKGAPIG CKVTLRRE-NA-EKFITTALGIVERQLAPSQFDRTGNVSFGIEEHTDFPGMSYDPTIGIY GMDINVVLEHK-GVRIARRSVERRKLPEAQRVSKEEAIVFMRERYQVEV----------- --- >GCA_011362975 -----MP-MRYK--KKKLK-YRGKR--THGGGNVKNRR-GAGNRGGKGR-AGIWKHRFSM VTA-----AGIK----------------------------L--G-------KH-GFSREK IKKE--EI--QT-----I-NVGEIER----YA----I-SGEL-KK---------ENGMYV FD--F------GGKVL----GAGTVTLPI-LVRA---KAFSKKAEKKLMDAGG--KAE-- KI--------------------------K------------------------------- --------------------------------------------------------MMVM ES-----------------IEKKFIEEPILKYRV----------------MRFLEENL-D KAWIANVDIQ------KSPVATRINLEVLDPSKVIGKKGKKINELSEVLQKEFKLENPQI NVV-EVKNQWLEPRIV----------AKKAAKGIEM--GKKVRGVLHSLLKNVMESGAIG VEIVAKGK-LG----------AKG-------------AKARSLKVR-------------- ----AGFIPKAGEPS-KAVKRAHYNAMTKSGIIG-------------------------- ----------INVSIA---------------TPDI----------YLPDK---------- ------------------------K-IEK------------------------------- ------------------------------------------------------------ ----------------------------KEEA---------------------------- ---------------------------GKKEGGG---------------------ERRAE GEEQ-------------------------------------------------------- -------KEQPS-----SAQPVKEE----------------------------------- ----GKHEGKGTEKS--------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MKANVYGVDGKVKK EIKLPAIFSE-ECREEIIRRAVLSEESKLRQPKGAYKLAGKETSARYKGEKD-T---FGS LKNRGQAKLPREFFG-KGR--WGRVRRVPHSVKGRRAHPPK-----VEKIIVEKINHREW VKALRSAIAATGDIELVQKRGHKVKE-S-----PIILSDDFEKIGKTKDFYSAL---SKI -IGEDLERSKNG-KKVRTGVRRRKGGVIYPKSALLVA-V---EDAA-------------- -----I-RAARNIPGVDAIKPEELTVRLLAPGAKPGRLAVYTESA---LKKIEEIWWKNE ------------------------------------------------------------ ---------------------------------------------MAKGPT---YVVPFK RRRMGKTRYKKRLALL-KSNKPRLVIRKKNREVIAQVVDFGYDGDRVLLTVTGKVISKQF GWP-----SRKNMPTAYLIGLYIAKLAKQK-GINDVVPDIGLHSPTKQSIVFGVMKGAID GGLNMKM--NMEI----S----DERISGKHIAAYAKALKEKSPEEYKKRFSSYLN--QKV DPEQIPDLFEQTVKKI------------KG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MRGV-PAKIVKTLIPGSRLVCNDNSGA KELMIIGVVG--WKGRRGRYPRAGIGDMVICSVKKGDPKMVGT---IVRAVITRQKKEIR RANGMRVVFEDNAAVLVTED--GLPTATEIKGVVAREVGE-RFPKVIAIAPGVA?????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????---------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------MITVKKDVWKGYTEE--------------------QLKEMPLDQFLKLV NARERRAIKRALE---ETNMEYRMLIDKVRKMKKSGKV-------KPIKTH-CREAV--- ------IIPEW----------------------------LGLRFLVHNG--------KEW K-----------PVDITLQRLGRR----------------------------LGE----- ----------FSFPV-KFIKHSG------------------------------------- -------------PGVGA-TR-------------------------------GSKFVPLK ------------------------------------------------------------ ----------------------------------------------------------MT ------------RAKARIRLEAEKPESINYVIEQIKQIAKTLDMKINGPIPMPRKKLLIA TRRTPCGDGS-------DTYERWEKRISRRIIEI-EGDEKNLRQILRIKVPDDVFVKIIL G----------------------------------------------------------- -------------------MGKKRTSRKKQYS-LPMHRRKAL-LSAHLSKELREKI---- ---------------------KKR-SATVKKGDKVKVMRG--DFK--GKTGLVASVDYKR ATVKVEGISRRNSRGV-DVLVP----------LKASNLMI-------------------- ---------IEK-KF-----------------------------------EEEKKKG--- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MG-LRPARTIRDP--------------- DK-VPWTRHSKVK---KKNFIKAI-PHQDIHTFVMGKR----QSDFNV-QVDLVAEDSY- -YHRDNALEAARKSSNGYL-EKKIPEK--YFFRVRPFPHHIIRENKMVA-GAGADRIQQG MRNSFGRPVDKAALVKK-GQAVITVYSY----KENVPLIKEALKRASRKL--SGRFKI-- ---------------------V-----VKEGGNFAI------------------------ ------------------------------------------------------------ --------------------------------MSVNLLAEAMNIIKTNSRVGKRMCTVK- YSKLIVKVLELMKSNGYIEDFEVVEDGK-GNKIKVML----------------------S GRINNCGVITPRASVKRQEWYKTEE--------------------QYLPGVGIGIIIVST PKGVITNRQAQEMKLGGRLIGFVY------------------------------------ -----MR-----------DIVVEVPNGVEVKSDGS-----AVYAK--GPKGEVSKIIK-- -----AKFTLSV-KDGK-VEVE------------AASPALKNTIKAHVRNLVKGVTEG-F TKKMVIRYAHFPVTIEAK---GNT--VL-IKNFLGEKKPRKAKIC--GNTKIEVKGQ--- ----EIILSGPSLEDVNETAANLRRATRIKE---KDGRV----------FQDGIYPAGEV E----------------------------------------------------------- ---------------------------MTDIRKPRAGSLAFRPRKRAEKELPRINFW-P- E-VS-----DKAVLGFAGYKVGMTTIGFIDQ-TNSPTK--GQEVLTGATILETPPMKVYG IRAYKNGG----------VV-DEYSE--DKE----ILKMLN-AKKINN------------ ----------K--------QIKEK------------------------------------ -------EWDNIFLLAFAQP-----NLTKIGKKHIERMEIGIGG--GE---QKLEYARSL LGK-DLCITDVFKPGQFVDVIAVTKGKGWEGPVKRFGVSMQRP--KATGRRRH--VGNI- GPFH-PGYTM-YTARMAGQLGYHKRTELNKWIAKIGK---KEEVELINPDGGFPHYGFVL NDFVILKGSVPGPVKRPVRMRLSIR-------KTTD-VLEP-KITYISREIR-------- ------------------------------------------------------------ --------MYSWK---------------------------------------PDDDQFAA K----------------------------------------------------------- -----------ARVEGVD-ASYKDLVEVCGNI--RRKKALDALSFLEKAAEGKVPVLFRS NNK-HLAHRK-----E----LCGKKGRYPKKAARVVLKVLKNALNNAAQKGL-MEENLFV AHVCANKKFTYPR----------LQPKG--RRTRHDYATARVEIIL-------VE----- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------RMAEKTTEK--------EGEK---K--- ------------------------------------------------------------ ---------------------MGKRIKTRI-------------RGKGTPRYRAPSHRYV- VDLKY--RNYDDIEKAGLLRGK----IVDFVDDPGRGALLAKIQYENGES-GFLLASEGM IVGNYVEVGA-------------QAK---LNPGNVLPLYSIPEGTTVFNLEKLPGDGGRF VRSPGSYALVVSK-EG--K-NVLVKMPSKKLVYFNPECRAQIGVVAGGGVKEKPLLKAGN AYYKWKARNKVWPITRGVAMSVYDHPYG-GKQH-HK---G-R----PSTVSRNAPPGQKV GHIAARQTG-------RKKVRQQAEGENK------------------------------- --------------------------------------------------------MREI LIDKVTVNIGVGTGGEALENAEKLLSEL-TGV-KPVRTLAK--K--RNPVFKLRPGMEIG VKATLRKG-KA-EEFLKKAFASKKNTIPASAFDNMGNFSIGVKEYIDFPGAKYNPKIGMF GFDVCVTLRRR-GYRVSRRKIAKSKIGKKHRITKEEAMEFVKNKFGVTI-EGG------- --- >Bin598_genes -----MV-IRKK--KKMLK-FRGHR--TYGYGSHKSHR-GSGSRGGKGK-AGGHKHKWSH TVK-----YDPD--------------------------R-Y--G-------KH-GFTS-- KTRK--NV--NA-----I-NVSMLEK----LAAG--------------------KKN--- ID--LAKLG--YNKVL----GNGALNVAF-EVTA---EMFSKKAIEKIEAAGG--KVI-- VLEKVK----------------------AG-KSETETPGVEEKI---------EEIGE-- ---------------------------------------------------------MAI E--------------------KTFVKEGIRGSQI----------------ENFLREKF-K RAGYSRSEIH------RTPVGMRIIVYANKPGLVIGRSGRRIQSITDEIKEKFGFENPLI DVR-QVDNPFLDANIV----------ASRVADSLER--GINYKRVCNYYIEKIMGAGAIG VQIRASGK-I------------AGV------------QRSRFQKFR-------------- ----KGFIAHSGDFADKFVDKGYAQAILRPGVGG-------------------------- ----------IQVKIMR-------------EMPA-------------------------- ------------------------EFI-------------AEKELDRK-IERDKEL---- ------------------------------------------------------------ ----------EKME-----------KELDEA----------------------------- ----------------------------------------------------KDEGNDA- -SAET--------------------------------EV--------------------- ---------EVIEVIEVVEEAETEDVKAEET----------------------------- ----TNEEKKTEEKID-------------------------------------------- ----------------------------------SK------EA---------------- ----------------------------------------------MKVNVYDMSGKATE KMDLPKVFST-RIRKDLIIRAFLSTMSKRRQAHGTDPMAGQRSSAHYHGRRR-KVR--WT MMGREMARMSR-LHGKIPGFLMYRARKVPQSVKGRVAHPPK-----AEKIWEQRINKKER QLAIKSALAATSNKIMVESRGHKIEDLKV-KEFPIVIVNDLQGISKTIELRKLF---EAI GLKKELERVQK--KKVRAGKGKMRGRRYKKKTGPLIV-V-T-KDEG-------------- -----ISKATKNIPGVHV------------------------------------------ ------------------------------------------------------------ -----------------------------------------MARKGKQKPT---RRMEFR RRHEGKTNYGKRLRLL-KSGKPRMVVRRSLRYIRVQIVEYDEGGDKTVAAITSQTL-KKF GW----EFAFDSTPAAYLTGIMIGKVAQEK-KISEAILDIGLYPSTKGSRLYAVIKGAVD AGLNVPH--DAEMLPD------ESRIRGEHIASHNE------------------------ KFKRLPEHFDVIKEKI------------VNEKIIN------------------------- ------------------------------------------------------------ ------------------------------------------------------------ EKNVKEKTEKKK---------------------MKPV-KARMTSPLSQGSRLTCADNTGA KILEIISFKG--YKGVKRRKPRGGVGGAIKATVKKGDVKIRKQ---VVDAVIIRQKASYR RKNGLRVKFEDNAAVLINEK--GEARGTQVKGPVAREAVE-RYSTIGKISKIVV-MKMAK K-------------------KSDGEARNIG---IE-VVA-PKES-----------C---- -E----DVNCPF------------------HGRLSVRGRVVEGDVVSAKAQKTVVIKRKY LHFIPKYERYERRHSRMLAHNPDCVD--AKTGDRVKIAECRPLSKTKHFVVVEV------ ----------IK---------------------------------------------KDL K-------------------------------------?????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????????????????????????????????????????????-------- ------------METARIKLSGKNPEELNEICVEIKDIAKKFGVNYKGPVPLPTKILKVT TMKTPCGDGTGH---GNTSYDKWEMRIHKRILDV-QADQRALRQIMRVNVPQGIHMSIHL KN---------------------------------------------------------- ---------MA-----RPKSKKPKKQRKYEKT-APLHARRKM-LAAHLSAELKKQY---- ---------------------GRR-GFPVRKGDEVVIMRG--KFN--KRSGKILRVSYKK YKVYIEGIMVKKTDGT-ERQAP----------IHPSNLKITKLNLD-------------- ---------DKR-RI-----------------------------------IALKKERK-- -----QKDVKKTVN---------------------------------------------- -----KLVKRK------------------------------------------------- --------------------------------MA-LRPGRTLKEL--------------- -K-RPYTRVSKRKP--RKSYVVGV-PQARIHIFEMGNK----RGKFEV-DVFLVSKDAV- -QIRSNALESARIVTNKHL-ETKLGLE-NYKFKILTYPHHVLREHSIAT-GAGADRFSQG MRKAFGRPSGKAALVKK-GQRVFVAQINN-N-PDHIKIAREALKRGSSKIRCKTAVEV-- ---------------------V-----VKSAKKK-------------------------- ------------------------------------------------------------ -------------------------------MLH-DPLADMMSIIKNAEKVGKRNCIT-K SSKLIKAILEIMQKHEYIGAFDFIDDGR-GSKFEIEL----------------------K GKIIDCNVIKPRYSVAAKEFEKWEK--------------------RYLPAREFGIIILST PKGVMEHTEAKKKKIGGKLIAYIY------------------------------------ -MYEKQ---------------FEIPEGVQIDIEKM-----KIVVS--GSKGTISREFI-G VFG----VKIEKDSENKIIKVS---TE-SDR---RKQKASIGSIIAHIKNMSNGVTEG-Y TAKLKSIYSHFPVTIKVD---DAKHNIL-IQNFIGEKTPRIAKIAG-QETKVEVKGA--- ----DITITGINIEEVGQTAANMEQATRIRN---KDRKV----------FQDGIYITEKP KGKIQ------------------------------------------------------- ---------------------------MPSKRKPRAGSLQFWPRKRAKRIYPRVSSY-P- S-IDTSALEKPKILGFATYKAGMLHVIMKDALKGSATF--GEDISVPVTVLDCPPMVAVG VRAYKMT--PNG-MA---VITEAWADKLPKDL---IL-----KKKLLKKTKAKIKAKSKK K---------GED------KKMKKAST-----------KKKTTASTHFAKMKKE------ ---ME--NIVAVRMIVATQP-----KLVGFGKKKSDVFEVEIAGKTTE---DILEFAKEA LGK-EIKSTDVVREGEIVDTIGITTGRGTVGPVKRFGVAIQGP--SAAGKRRH--VGSL- GQES-PGKVR-WTVPMAGQKGFHQRTEHNKRVLKMNDAEDAGK--EVNPKEGFPHYGVIK GPYIILKGSVPGPRKRLIFIRTAIR-----P-VRKT-FTVP-EIKEIVR----------- ------------------------------------------------------------ ------------ED-------------------------------------KEDKEDKEE KKLVEEKAIEEKEIVEEK-QKEVKA--------------EEKKPIEVVAPKEFVLP---- -KRKKSKVFGNAKFTDAR-ISLKSSKIICKEL--RGKRLSKSKMLLNGLLDEKKSLN--- -------------------------GKYYTKTVKKILEILTNAEANAVAKGL-DDERLFI YSINADKGRTFIRPR-----------SKMSRRGERAKM-THIEIIV-------GEK---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------?? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????????????----------- --------------------------MVDKDTN----------------------KMREI SVEKVTVNIGCGGDAKEIERAQKLLGALASGK-KSVVTLSR--R--R-STFGVAKGRPVG VKVTLRGK-DA-IDFAKQALSGIENQLKISQFDDDGNFSFGVKEYIEMTGIKYDHDIGML GFDVSVTLRRA-GFSVSRRKIQTRKIPKRHKITKEESVEWAKRVLDVKI-V--------- --- >GCA_011365055 ----MKT-KRTP--KRRLK-FRGSR--EHGYGKIGQHR-KAGQRGGKGKYTGGQKHLWSY IVK-----YEPD--------------------------Y-Y--G-------KK-GFQRPP FYMH--KM--KI-----V-NVEDLET----IA------------I---------KNNSND LN--LIEFG--FEKVL----GKGTITKAL-KITA---KAFSKSAIQKIENAGG--QCI-- PSNTLK------------------------------------------------------ ---------------------------------------------------------MPV K--------------------EQFIGRKITKTQI----------------DEYFENEL-Q KAGYSELDIQ------KTPLGTRIIIHAARPGLVIGKRGKNIRLLTTYLEENFKIENPQL EVA-EIEVPELNAKVM----------AQRLASRLEK--GTHYRRAAYSVLRRVKSSGAKG VEITISGK-L------------TS-------------HRAKYKKFR-------------- ----EGFVAKCGEPANLHVDEAVAYAIMKKGVIG-------------------------- ----------VKVKIMH-------------LPENA----------ILPNEI--------- --------------------------I--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------L---- ------------KEEKEIEENNE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MPEAEILNLEGKLIE KLDLPEIFST-DYKPWIIRRAQIAVQANRKQPKGRDPLAGKRNTAESRGPGH-------- ----GIARVPR-VKG-SGTRRASAGAFVNMTVGGRVAFPPV-----PEKVISEKINKKER RLAIRSAIAATANKDLVILRGHQFD--DN-VKFPVILSNELEGIKTTKEIIEIL---IIL GLYPDVERA-SV-KKIRAGKGKMRGRRYKKKKGILIV-G-K-VTEN-------------- -----LHKAARNIPGIDVSEVRNLNADLLAPGGHAGRLTIWTKAA---IEELNN--LFK- ------------------------------------------------------------ ---------------------------------------------MADGPR---YRVKFR RRRQGKTNYYYRKRLL-TSELPRLVVRKSLKHIKAQIINAEMTGDKIIIQAHTSELSKNY DW----KYNTSNTPAAYLTGYLIGKKALKN-KIESAILDIGIYRPIANTKLFAVLKGALD AGLDIPH--GEEIFPS------EDRIIGKHIVDYAAKLEEEDKSLYKKQFSKLLK--NKF DPKQISSKFKEIKQKI------------DKNIK--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------MGKRRVR-----KT---SSLI-LPKTSRAIPTNAQIKSSDNSGA RILKILSVMK--HKTRLNRFPSAHVGDMVVCSVVKGTPEMRKQ---KVTAIIIRQRKPFR RKDGTWMQFNDNAAVVTSNL--GDPKGSEIRGVVAKEAAE-RWPRLSSVSSSVV------ ------------------------MTRDIG---ID-VKI-PKKI-----------C---- -D----DPNCPF------------------HGKLSIRGRILEGIVSSTKMQKTIVVRRNY LRYIKKYNRYEKRHGTIHAHCPDCQI--PIEGSRVKIAECRPISKTKSFVVIEC------ ----------ED-------------------------------------------TGED- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MVRKFTYRGYSLE--------------------ELVAMPMDEFIKLI PARQRRSLLRGL------PRRQKKLLENLRRAKRAL-KKGKTV--V-VRTH-NRDMI--- ------IIPEM----------------------------VGLTVGIHNG--------KEF I-----------EILITPEHIGHY----------------------------LGE----- ----------YAPTH-KRVSHGN------------------------------------- -------------PGIGA-TR-------------------------------GSQYVPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------VQKARIRLSSTNQDKLLDICNQVGRIVQRTGVRISGPIPLPTKKLVVP VRKSPCGEGT-------NTWEKWQLRIFKRLIDI-DADERTMRQIMRIRVPEDVFIEIEL K----------------------------------------------------------- ---------MR-----KIKTKSPGKQRKRLYT-APNHKTSRL-FNVKLMSDLVEQH---- ---------------------GVK-RLPLRKDDHVMVING--EFK--DIEGKVTKIDRKK IQVFIDGAKIEKKGGG-EFDLP----------VHPSKLMITKL--K-------------- ---------DDKYRE-----------------------------------GIIERRKREI ------------------------------------------------------------ --------KEVIIK---------------------------------------------- --------------------------------MA-KIKWKSWRDI--------------- -KGKAWVLRWKKTGKGRRYYIKHA-PDAKIRMFTIGK-----EKPTHYWKATLVSKEAA- -QVSHLTLEATRISCNRYL-RAKLGRD-NYLMRILPYPHHIVRQHKLMA-FAGADRLQSG MRHAFGKPFGRAARIKT-DQQLLYVKV---S-KNDLDIAKQALRRAKMKW--PMPSKI-- ---------------------V-----IEKINADE------------------KEIK--- ------------------------------------------------------------ -----------------------------M-VLL-DPLANALVNLKNCEVIGKREVIIHP ASKIIAAVLRIMQKAGYIGEFEFIDDGR-SGKFMVQL----------------------L GRINKAGVIKPRYPIQKNQIEKWES--------------------QFLPARNFGLLIVST SQGIVSHNELRELGIGGRLIAYVY------------------------------------ MVKQDYI-----------EQSYEFPKNIDFTLKEK-----ILTVK--GSLGELIKDFS-H A-R---KIDIQI-KDRA-ILFS---CA-FPK---RKERALVNTLAAHVKNMVDGVLNGPY IIKMKIVYSHFPITVKTE---GNQ--VL-IENFLGERAPRRALIFG-KNTKVKVDGD--- ----DVVVESINIEEAGQTSANIRKTCKIKN---KDPRT----------FQDGIFQYQKL LNETVIWNLKF------------------------------------------------- ------------------MG-------HRKYNAPRHGSLSFIPRKRSRHKNGRIKTW-P- N-YE-G---EPKLLGFAGYKAGMTHVIYVENMKTSPFV--GLERSRPVTIIEVPPMVACA IKAYKKS--YTG-LI---TLGEAWASELTDD-----L-----KRLF-------------- ----PQS---KEY------DSDKA-----------------------VVELEEK------ ---VK--DADELRLSLHTQP-----RLTAVPKKKPDLMEVKIDGGKIE---NQFKFAKDL LGK-EIKISDVFREADLIDTIAVSKGKGFQGVVRRMGIKILPR--KSRKTVRG--VGSI- GPWK-PARVS-YTVPRSGQMGFHHRTEYNKRILKIGI---DPN--EIAIKGGIVNYGVIK GDYILLEGTVPGSNKRLIKIRHSIR---P-K-KTIP-KEVP-ELVHISLQSKQGK----- ------------------------------------------------------------ ---MSPNYGYSIT---------------------------------------GLDPEKTA K----------------------------------------------------------- -----------ASGRDIR-CSPKACREVCNFI--KGKKLEDAKEYLFQVIELKKAIPFKR HNK-HVAHRK-----GLD--KWSA-GKFPRKVANEIMTVLEAAEANAEYKGL-DIDKTII KHAAVSRGPIIKKNIP-------RAFSR--SSPYYKLL-THIEIVL-------EEK---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRLRVQR---------------KSSKVFRAPTHRRI- KPIKY-----I-LQEEKKRDAE----LLEFHHEIGRGAPLGKYILDNKEL-TFFLVPEGV QIGHKIEIGH-------------DAS---VNIGNVLPLYKIPEGIPIFNIEANPGDGGKF IRSSGSYATIQTR-SK--E-KIVVKLKSGKFKNFHPLCRATIGIVAGGGRTEKPIVKAGN KFYQTRAKGIYWPVVRGVAMNACNHPHG-GGNHQHI---GKK----GSCVSRNAPPGRKV GLIAARRSG-------RKKR---------------------------------------- ----MDEEKDNI----------------VEISN---------EIRKKFHENWSKHPMRKP RIEKITVNVGVGASGLQLEKAMNVLESL-TGQ-KPVKRNSR--K--TIRGWGIRKYEPIS TIVTLRGE-QA-VEFLKKTLEIHENQILVGAFDDLGNFAFGVKEHIEIPGTQYDPKLGIF GMDICVNINRR-GHRISKRSYRRKKIPKRHKMEKDEAMTFLQDEFGVSY-IRQHIISYY- --- >GCA_011364925 ---------MKSYYLKQKE-------------------------------LG-------- -------FPDPD--------------------------WDL--G-------KR-GFKRPQ DIRRIYHI--NT-----L-NIKDLDS----KIDDLTV-KNVA-TK---------SGNTYS IN--LKDIN--IQKIL----GRGEINKKV-NLTV---NKASKRAIEKIESAGG--KVT-L LTEAD------------------------------------------------------- ---------------------------------------------------------MPL A--------------------KHFIEQGIKLMQI----------------NEYLRSEL-V RAGFAGVDIQ------KTPLGVRITLKTSRPGLVIGKAGKRIQEITDVLHDRFGLEMPQI EVE-EVPNPDLNAQIM----------AERLAYSLDR--GRHYRRAGYYILRKIMDSGARG TEIIVSGK-V------------TS-------------QRARTTVFR-------------- ----AGTMSKSGQPAQEGVDRGVAQCIQKSGTLG-------------------------- ----------IIVKIM---------------HADT----------RMGDTV-KIDDASLA KIQTKKLSELTKTKAE-KDY----E-V-------------IEE---------ERDL---- ------------------------------------------------------------ ----------TAVE-----------KELFDEVEEDD------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------TSELYLDSEKETDEKT---------------------------------- -----EE----------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------MEKVNIYDLDGKKKN LVDIPQLFYS-KSRKDLIQIASEVASSKNKQAQGRNKSAGLRNTAESWGTGH-------- ----EMSRAPR-IKG-SGFSTARNVGRVPFAKGGRRAHPIK-----TEKNIEKKINKKIH KLSIISAISASGDSEWVKNRGHKID--KV-PEIPLVVDDKIQTVRKTKLIYSIL---TEL GLKDDLIRVKKS-KKIRAGKGKRRGRKYKIRKSLLIV-I-K-DDFG-------------- -----IVKAARNIPGIDVVKLENLSIAHLAPGGLPGRLILWAQSA---FNELKKYEELI- ------------------------------------------------------------ ---------------------------------------------MAKGPR---YRKPFR RRAEGKTNYHRRLKLL-KSKKLRAVIRASNNHMIVQIIRSKTAGDEVVISAFSKELVSKF GW----NANTGNIPAAYLTGYLAGLRAKKQ-NIEEAILDLGIF--YHKNRVLAAFKGLLE SGLEIPF--SEDFFPN-N---IEETIKGSHIEQYANFLKNENSEEYEKVFSGYLKK-NNV NPQKISQLVANTFKKI------------RSST---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGTRR--KLGR----KKQI-KPRTSYGVQNGSKIFITDNSGA KIAQIINVDH--SKTRLRRLPKASVGSVCSVTIKKGRPDLRGN---IVKAVIVRQKMIYR RLDGTRLCFEDNAGVIITKE--GDPKATEIRGPIAREAAE-LFPRLASISSLII------ -----------------------MSVRNIG---IPGVNP-PTAR----------EC---- -S----DKDCPF------------------HGTSRIRGKITKGVVVNKKSKNTVVIRQDY VQFVKKYQRYERRNSRLVCHLPECLNHVIEIGDLVRVGESRKLSKTKAFIVLDK------ ----------IR-------------------------------------------TGAD- ------------------------------------------------------------ ------------------MPPNEEQD-NEEQEE--------------------------- --------IEEEDLEEEFPEELEEE----------------------------------- -AERGELDLEKERDRLKFHYRGYTLE--------------------ELKKMSMDEFIQLL PARARRSLKRGL------PPRQKKLLERLRRAYRAK-KRGKDI--L-TRTH-VRDML--- ------IFPEM----------------------------VGLKIGIYNG--------KSY E-----------TVDVKPEMIAHY----------------------------LGE----- ----------FSLTR-RHVQHGS------------------------------------- -------------PGIGA-TR-------------------------------SSKYVPLK ------------------------------------------------------------ ----------------------------------------------------???????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- -MKV--------------KSKHPRRQRKALYQ-SKNHQHSKL-LTARVADFVTEEY---- ---------------------GIK-TLPIKVGDEVRITQG--EFK--DFEGEVIEL-TRN QRVKIKEATFDKADGT-QFHPA----------IHVSKLIITKFSKEK------------- -------KMDPW-RA-----------------------------------SIIDRKAVFG F------------------------------------------------------TGDEL KAPKKQKEEEEK------------------------------------------------ --------------------------------MAHKRPWHCYSTW--------------- -NRRPYQHKRSANH--RREYARGG-SQSKIVRYWGGNKDIP-WESWEL-VIGLKVEKQI- -QVSSNSLEAIRITVNSAL-QTYLGRT-GYRFRVRSIPFQKYRENRMLA-FAGADRVQSG MRNSFGRSTGVCARVRA-GAIICEVGT---S-LKNLPIVRDRLRVASMKV--ASHCSI-- ---------------------V-----ILKYKTPEIFKQ--------------------- --AGLPLY-------------------DDKKRKEVPLFEFAVV----------------- ----------------------------------------MCNDLKNAEKARKKEVIVSP ASKLNQRVLRIFQQYAYIGEFERYDDGR-QGKFKIAL----------------------L GKINHCAGLM-RLNYNESQFESLER--------------------RLLPAPGLGIIVLTT NQGIMTLKEAEEKHIGGMTLCYIF------------------------------------ MVKVAYF-----------KEEMEIPEGIKVTLDEN----HHITIN--GPNGKITKDFS-H VRG----ISVTI-EGNK-MIFT---TH-FPK---SGTLALINTVINLIRNLIIGVQTN-Y KYVCKVCYSHFPCTVEVI--PDKK-EIH-VVNFLGERAPRVTNYL--DNVKVKVEGD--- ----DVFLIGPDKETLGQTAANLRKACRIRK---KDPRV----------FQDGVFLYRIQ NGEEIAWEVK-------------------------------------------------- ------------------MG-------HRKKHAPRHGSLAFLPRKRAAITKGRVRRW-L- N-TSD----SLIFLGYAGFKAGMTHITYIEDQKNSPYF--GKELMKPVTVIEVPPLILIG IRVYNED--EYG-KY---IVGDIFSTELNDY-----L-----RRKI-------------- ----SIPN-FENY------DFEST-----------------------KEKLIKA------ ---LN--NTSQIRGIFQTQP-----HLTSLPRKKPDIIEIQVNSVGDSV--EEFNFALNL LGN-EIRVRDILIEGELVDILAVTKGKGFQGPVKRFGVRLLTR--KNNKVQRA--VACI- GPWH-PARVL-YTVPRPGQLGFHQRTEYHKRIMVIGE---NEE--EINPKGGFVKYGKVK GDYLLVLGSIPGPKNRLVRIRKTIR---P-I-KTFT-VKSP-EITFICRESQQRK----- ------------------------------------------------------------ ----MPNWGYSFTE-------------------------------------QKYDADRLA K----------------------------------------------------------- -----------ASGRDLR-IKPKPAREVCAVI--KGMKLDQAKSYLEKVIQLKQSVPFRR YKK-KLAHRK-----DLKQFNWYT-GRYPQKAAARIYEVLTSVESNAEFKGL-DTEQCRI IHAATHRGRIIKRYIE-------RAHGR--STAKFRHL-SHIEIVI-------YEFPS-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRILARR-------------KGYGNLWARSPSHRHV- GEVKYR----PFKKNEKTLKFK----VIELVHAPGRGTPIAKIKYEDGQK-DLWLPPEGI YEGQEFIQSK-TGY---------GQE---VKVGNILPLRKVPIGTLVFNIEGTPLDGGKF ARASGVAAIVRNR-SG--K-NIELLFRSKKTKWFDQNCLCTVGVVAGGGRTDKPFLKAGN AYHAYSSKAKKWPVVRGVTMNATSHPYG-GGAKQSP---H-K----PTTTSRNAPPGRKV GQIAARRTG-------HQN------------------------------MSAK----AVR EMMKKSSKEQEKIFEE------------MWK-N----------------------PMKKP YLEKVVLNIGVGAGGEELERAATVLQTI-SGK-PAIKTLSK--K--NVKEFNLRIGRPIG TMVTIRNK-EA-ENLLKRLFVVNNDRILRKSFDNYGNFGFGITEHITIPGIEYDNIIGIW GLDVVGRIVRP-GMRVKYRRKGRAKVPKHHYVSRLEAQYFLKKNFGIKI-VDKLDLDFA- --- >GCA_003555225 ------M-DSKI--KKSRK-QRGGR--THGWGAGKKHR-GAGSRGGKGM-AGTGKRGKSR K---------QAV-TGI--------------KN-----Y-F--G-------KY-GFT-T- KRRN--FV--TS-----A-NIAYLEK----NGESLLN-SKKA-EL---------KDGFFV ID--LENIG--IDKLI----SKGKPTRKY-KITC---FTATKRAIEAVQESGG--EVH-- F---------------T-----------N---QEGLEE---------------------- ----------------------------------------------------------MI H--------------------KKLVQEKIKDYQI----------------QNFVKESL-K GVGLSSTKLQ------VTPLGEKIVVRAARPGLVVGRKGQSIKKLTNMLKKKFGLENPQI EID-EVKDTKQDPAIM----------AETIASYLERFGSARFKSIGHRCLEDAMKDGAYG AEILITGK-V------------PS-------------SRSKSWRFY-------------- ----KGYLKKCGDLSITGVKKAYATANLKTGSIG-------------------------- ----------IQVRVM---------------PSDI----------RLPDKV--------- ------------------------E-I------------L-DQPVTE--VE--DVT---- --------------------------ASQET----------------------------- --------VEEETKS----------EKEESGK---------------------------- ---------------------------KETKT-----------------TKKTESKESGK ASENKKST---------------------------------------------------- ------------GKKTTTKKTTKKKTDG-------------------------------- -----KATTKKTTTTK-KSTAKK------------------------------------- --------------------------------STKK-----STGKSE------------- K---------------------------------------------MKVPVLNKSNDEVG KIDLPEQFNE-EVRKDLVKRAVLAINANSRQKYGVFHRAGKRHSAKLSKRRN-V---YRS GYGHGISRVPRKILSRRGKQMYWVGAVAANTVKGRRAHPPK-----VEKNWERKINKKER RVAIRAALSASANKDYVVERGHKVP--E---NYPFIANNDFEKMSKTKEVIDAL---NNL GFSDELNRVSI--KKIRAGKGKIRGRKYKRKVGPLIV-V-S-DKCE-------------- -----LEKAARNIPGVSVEVVQRLNAKTLAPNATVGRCCIFTQKA---IEKIANEKLFMN KVGEK------------------------------------------------------- ---------------------------------------------MARKSV---KTVPHR RRREGKTNYKNRLTHL-LSKKPRLVIRPTTKNMVVQFSVYNPDGDITKVKVNSGVL-EKY GW----KFSKNNLPACYLAGFLAGKKALSS-DVKEAIADLGMQNKSHGGKIYAALKGVID AGVNIPH--SEDCFPT------EERITGEHIKNYVSNVKEDST-----QFSSYKK--NKL ETEKISEVFENTKKKI------------LES----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKPI-KARVTKSLPVGAYVDVCDNSGA KLLKLTNVRK--QKTAKGRVPSAGVGDLVMGSVKKGKPDMRKK---VVLAVIVRQKKEFR RPDGTRVKFEDNAAVIVKDPK-GNPQGTTIKGAVSKEVTT-RYPGIAKVANIIA---MIL LT---------------------QETKNIG---FG-IKA-PKEA-----------C---- -EG---DKNCPF------------------HGERNVRGRTLVGKVIRAKLPKCVTIECTT NKYIPKYQRYKKLRTRIKAHSPECIS--ASEGERVKVMETRKISKTKNFVVVEK------ ----------VEA----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFTFRGKSLE--------------------ELKKMGREEFAQLL TSRKRRTLLRGP------REEHKRFMEKLNKKQD------------NVKTH-CRDMI--- ------ITPEL----------------------------VGKTVKLHRG--------KEF D-----------PITIQPEMIGHY----------------------------ISE----- ----------FSFSK-KRVAHSN------------------------------------- -------------PGVGA-TK-------------------------------SSSNVSVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLASTEIDKINQVCNYIKDIAEKTGVVMRGPIPLPTKKMKIT TRKSPDGEGK-------ATWDRFEMRVHKRLIDL-GIDERALRLVMRVPIPEGLNIEIEM IEG--------------------------------------------------------- -MAK--DFSRS-----WRSSRQPDKQRKFIYN-APYHLRGSL-MTSLLSKELRKKY---- ---------------------NKR-SLRLRKGDKVKVMRG--QFK--GKQGVVENVDLKN YKVNIENVQMNKKDGT-TTYYP----------LHPSNLMIIDVYKE-------------- ---------DKK-RF-----------------------------------SRIQPKKE-- -----ASQQEGEV----------------------------------------------- ------------------------------------------------------------ --------------------------------MARLRKFCAYRRL--------------- -D-RPYTRKSKYR---NLSYIKTS-PNIKIVRFEGGNL----KREFPA-RVDLVSREPL- -QIRHNAIESARLTANRYL-EKKVGKH-EFRLSIRMYPHHVLRENPLAA-GAGADRMSTG MKRSFGKAIGKAAQVWV-GKPVLSVYV---E-KKHADSAKKALLRASKKF--PGTYTV-- ---------------------Q-----IHS------------------------------ ------------------------------------------------------------ -----------------------------M-AMN-NPLAAVLSHIQNCERVGRTETIVRP GSKIVKNVLDILNNERMIGETELLEDKR-GNSLKVYL----------------------I GKINKCGVISPRFSVKKDSFERFEK--------------------QYLPAEDFGVIIVLT SQGMMTHKQAKEKGIGGRLLAYCY------------------------------------ MSSKNY------------VEEIELLEGVSASREGK-----MIQVK--GPKGEVTKTLY-N P-L----ITMEV-KDNK-IELR---AD-RYG---RREKTLIGTYRSHVRNMLKGVTEG-H YYTLKICSGHFPMNVSFS---NNV--LT-VKNFIGEKVPRTLNVS--NKVNLKVEGD--- ----QITIESPDKDVAGQTAGSIEKLTKRVN---FDKRI----------FQDGIYIIEKD GKKLA------------------------------------------------------- --------------------------------------MQFWPRKRAYRSVARVRYW-A- K-SD-----KANLLGFAGYKVGMTHVMAEDTRQKSTTA--GENISIPVTVIECPSIKIAS ARFYKKK--D-G-LK---LVTEVFAKP-AKE-----L-----GRKI-------------- ----PLP---K--------KSEKK-----------------------IEDIN-------- ---PD--DFDEVRVNVYTQP-----RFTGMGKKKPDFFEVAIGGNK-E---DAFAYVKEN LGK-EISVKDIFSEGQIVDTHAVTKGMGYQGPVKRFGVSIRSS--KSEKVKRG--PGSIA GGWKAHGHMM-YRVPDAGQMGYHMRTEYNKQIVSIID---EPE--KVNPEVGFVRYGNVK NTFLLIKGSVGGSRKRLVRLCMPIR---P-K-KQAP--EAP-KVLEINKNSKQGK----- ------------------------------------------------------------ ----MAEHKYSFK---------------------------------------NYDPETMA R----------------------------------------------------------- -----------AVGRSLP-VSTKHCIEICNYI--RGRKVSVAKGLLRDAVALKKPIPFKR FNA-DVGHKK-----G----GFSA-ARYAVKAAGEVLKLLDSCEANAQNKAL-NTGDMVI THINAHRGSQQFRM------------GR--QRRRRMKR-THVEVVL-------EEVSKKR ----ESKESKTQAKEEDKKPD--------------------AETKTPSKEDKKTNDD--- --------KVQKKEAEVSETKKDEEV-------KSEEKS-----------VSS------- ----KETKTKEKQKEKATTKKKAAQKTT--SEKDNKQDTKD--------EKSKSEKNSKS ------------------NKAETNEA---------------------------DGKK--- ---------------------MGKRIISQR-------------RGKGSARYRAPSHNYF- AKASH-----LSSHDG-SIKGK----IIDLIHSSLHSSPLMKVEYENKKV-VFSPAPAGI RVGEEIVSG--------------SKE---SKKGNTLFLKDIEEGTFVHNIESQPGDGGKF VRSSGGAARVVAK-YE--N-KVFVVMPSKRKKTFSPLCRAAVGVVAGAGRKEKPFVKAGN KYYKMKARNKLYPRTEGVKMNAVDHPYG-NSRSSNK---G-H----PTIARRFAPPGAKV GKIRPRRTG-------KKIGRASKRN---------------------------------- --------------------------------------------------------MREI YIEKLTMNIGAGRDQDKLEKGVKLIEYL-TGI-PPVKTKTS--K--RIPNWGVRPGLPIG CKLTLRDS-KK-KELLKKFVEAKDNVLKSSQFDENGNISFGIHEYINIPGAKYHPEIGIM GFQISITLTRP-GRRVSSRKLKSKSLPQKQRVSKKDAMDFMKKEYNVEI-VD-------- --- >Bin101_genes -----MT-VNKR--KKITR-QRGQW--THGYGSKKKHR-GAGSRGGKGM-AGSGKRGDAK K---------PSVWNI---------------KN-----Y-M--G-------KH-GFTSK- SRRI--ED--KT-----V-NIGYLEE----NLSSLEK-QGVA-EK---------KGDAYN ID--ISKLN--CTKLL----GSGKITKKY-EITA---LVASAKAVEKIKALGG--KVN-- T---------------------------LQPASSSPEAEQPE-----------EPKKDAS DTAEA-----------------------------------------------------MI E--------------------RKFVAENIKIFQI----------------QEYIEQSL-K GVGHSHTKLQ------KTPLGEKITIYTSRPGLIVGRKGQNIKNLTSTLKKKFNFENPQI EIS-EVTELFLDATIV----------ADMIASSLERFGTSKFKGVGHKMLANVMNSGALG VEILISGK-V------------PS-------------SRAKRWRFY-------------- ----SGYMKKCGDISIEGVKHAIAAAHLKTGAVG-------------------------- ----------INVRIM---------------PPDI----------KLPDNI--------- ------------------------N-L------------R-EP----------------- ------------------------------------------------------------ ----------DAVV-----------EEKNSEE---------------------------- ---------------------------QEEKE---------------------AGKKTKK KEKKGEKD---------------------------------------------------- ----------SDKKTKVVKKNSTQSRDLS------------------------------- -----TKSKAEDAAETKEE--KE------------------------------------- --------------------------------VTE-------KAINE------------- AE--------------------------------------------MELKILSTDNSEKG SQKLPGQFQE-AMRPDVISRAVFALQANARQPYGASPGAGKRHSVELSRRRH-N---YRG AYGFGISRVPRKIHTRRGTRMYWVAAEAPGTVGGRRAHPPK-----PSKDYSLKINKMEN RLAIRSSISATIIKSLVTEHGYNVP--K---NYPFIIDNSFEALSKTKDVKQAL---IKL GFEQELKRADK--KTVRAGRGKLRGRKYKKKTSLLFV-V-S-KDCE-------------- -----LLKGAKNIAGIDVAIVNALNAELLAPGAKSGRAALFTKSA---VDRLEKEKLYTE AYKG---------------------------KIVKKEEKKTER----------------- ---------------------------------------------MAKNKI---YTVAYR RKREGKTNYKKRIALL-KSQKSRLVVRLSLKHVTIQIIQFNPEGDRVLVSAHTSEL-GKL GW----GASTGNIPGAYLVGFILGKKALAK-NINEAILDIGLRTSVKGSRVYAALKGASD AGLKVPF--SEEIVPS------DNRIMGKHVADYALTLSK-NQDAYKKQYSQYMK--RLL KPEQLPEHFGEIKKKI------------EVSIK--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MQAV-TSSITKALPVGTVLETCDNSGA KEIKIIAVIG--AKTVKGRIPSAGVGNLIMAAVQKGKPEMRKQ---VVHALIVRQKKEYR RADGTRIKFEDNAAIVLKDNK-GNPKGTIFKGAIAKEVVD-RWAPISKIASIIV---MAK QP----------------------KPKNIG---IK-VAI-PQKF-----------A---- -D----DPRCPF------------------YGNLKVRGRKFTGTVVSDKMNKTATVQWTR YKLLTKYDRYEQKITKVHAHNPDSIG--AKKGDKVVIMETRPLSKTKSFVIVEKLGR--- -----DIDYEIK---------EQSIEVDSEN---------------ISEK-------EKR KQEADKTEPSEVPDEQGKELKENKEKQEGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVKKEFAYKGKTLQ--------------------ELQQMSVTEFSEIL PALQRRKIKRGF------TDAEKAFIKKLEKKGN------------NVKTH-CRDML--- ------VLPSM----------------------------VGKIIRIYNG--------KVF E-----------PITIQPEMIGNR----------------------------FGE----- ----------YVLTR-NRVAHSA------------------------------------- -------------PGVGA-TR-------------------------------SSSAISAR ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKIASTDIEKINSVCDYIKQIVEKTGVIMRGPIPLPTKKLKVT TRKSPDGEGT-------ATWERYEMRVHKRLIDL-GIDERALRLVMRVPIPEGLNIEIEM IES--------------------------------------------------------M LMKQ--DFSPK-----WKSSKQPRKQRKYRYN-APLHKRQKF-LAATLSKELRKKY---- ---------------------GTR-AVPLRIGDEVTVMRG--QFK--GKKVKVERVDMKR LKVYLTKIESTKKDGT-KTSYP----------VDPSNLMITNLDTD-------------- ---------DKK-RLKQ------IKHVPL---------------------QTVAKQSS-- -----VQTEKTAVVTSAP---------AATPKQA-------------------------L SSPSPSQSQSTKEVTTTKTLVAKTAESP----------------AKKNKGVE-------- --------------------------------MAKLRKGCSYREL--------------- -Q-RPFTRKSKYK---KKAFIKAV-PNSRVVRYNMGNP----KKQFTT-KLELVSKTDL- -HLRHNCLESARLSSNRLL-EKILGKT-AFYLVINVYPHHILRENPLAS-GAGADRMSTG MKKAFGKSVGVAARVRK-GQTVFTVSV---D-KENFNTAHLALQRATHKL--PNSYSI-- ---------------------RA----VSD------------------------------ ------------------------------------------------------------ -----------------------------M-SLN-DNLANAMSRILNSERVGKHECVIKP VSKTIKKLLDLLKTHKYIKGYKLVEDSK-GNILIVSL----------------------T GRINKCGAIKPRYAVKQDNYEKFEK--------------------RYLIAKDFGILIVST SNEMMTHIEAKSKRLGGRLVAYCY-----------MSDARN-----------------TT GKRKTL------------VYTIAVAEGVQVGITDG-----LFVTK--GAKGEVKRKLM-H H-G----ITAAA-ADGK-IVLT---AE-NPT---KREKRMLGTFKAHIQNMMKGCSEG-H TYKMKICSGHFPMSVSVS---NNQ--LI-IKNFTGEKMPRVLDIK--QEVTVKVEGQ--- ----DVLIESTEKELAGQAAAGIEQLTKRPA---FDKRI----------FQDGIYIVEKD GKPVKK------------------------------------------------------ ---------------------------MGKAHKPRSGSMQFWPRKRAKRLVARVRAW-P- K-AS-----ESKPLGFAGYKAGMTHAILVDNGPHSKTK--GKDIFSPITIIECPPLKILS IRFYKIN--KNP-EKH-LLATEVISEKPDKS-----L-----AKKL-------------- ----TMP---K--------K-AKK-----------------------LESIK-------- ---PE--DYDYIRLLVYTQP-----RLTGIGKKKPEILELGLGGKK-E---EQLAFAKSK LNT-ELAVGEVFSEGQQVDMHGITKGKGFQGPMKRFGISRTQS--KSEKAKRN--PGSL- GGWKAQGKVM-YRVPHAGQTGMHQRVHLNGFLLKIGS---KPE--EINIAGGLLNYGLIK NTYLLFKGSIPGARKRLITFTLSAW---P-N-RHYP-KDAP-AIAYLSTLSKQ------- ------------------------------------------------------------ ------------M---------------------------------------KDVNEHMA M----------------------------------------------------------- -----------AMGIGLP-ISTKMSIEICNAL--RSKSLQDSKTFLQNVICKKQPVPLKR FNM-DVGHKK-----G----HIAA-GRYPIKACSHILKLLESVEANAQLKGL-NTGSLRI CRFVPNKGVQTMHG------------GR--QRSRQTKS-TNIELIV-------EETAAK- ---------KKEEKSTDSQNSSLTSGLTSSVSAKADTSSQARMKPEVKPVEQKPVQAPAP TPVSKPIPKAIPKPVQLKQETPPPAPVK----PLPESKPEPIPAPVKPKPVHSKPAPVQI PEPAAPKPITPQSQSQSQ-PQAVESQPS--IKPEPKEEPK---------EEPKEEPKESS LFDDVKNVQNLLDKSKKVAKSAKSK----------------------------EDRK--- ---------------------MGKNLIQQA-------------RGKGGPTYRAPSFRYR- GKVTH-----KTFNQKQTENGT----IIDLLDCPGHSAPLAVIQYKDGEK-ALGIAPEGV CVGQPVQIGE-------------QAE---VKTGNVCMLKNIPIGTLIHNIESQPGDGGKF VRGSGVFAKIVTQ-KK--D-RIVVMLPSKRQRDFLPNCRAGIGIVAGAGRVEKPFVKAGT RFHAMKAKNKLYPITSGSAMNAVDHPFG-NKRTSRK---S-K----AVSVSRNAPPGRKV GMIAARRSG-------RKKK---------------------------------------- -----------------------------MTQN----------------------SMRQV VIEKITLNVGAGKDQKKLEKGLKLLKNI-TGL-NPIKTITA--L--RLATWGIRPGLPIG CKLTVRKQ-KA-QEILKRLLAAKDYRLNPKQFDNNGNISFGINEYIDIPDVRYEPDIGIM GLEVCVTFQRP-GFRIKRRRLLKRKIPGRHRVTKNEAMDFMTKHFGVSM--GSED----- --- >GCA_016198125 -----MV-VRRS--RKVHK-LRGHR--VHGHGDTKNRR-GSGSHGGMGR-SGSHKHKYSS YYAT------------------------------------F--GV------KK-TLNPKQ GEKQ-----KKT-----L-DLDDVSR----LVQEWTD-SKTA-EK---------VEGRTL VD--GVKLG--VHKIL----GSGSIQVPV-HVRN---MQVSSKAKKKIILAKG--AIE-- GLKESEA--------EELAFEAGAEEDNETVNSEADEN-PEMHA--------REEGSGE- ----------------------------------------------------------MI E--------------------RHFVKQGLKKVQL----------------EQFLRKEL-D KAGFTELDIV------KTPMVTRIVVNVAKPGLAIGKGGQNIRSLTDEIGRRFQIDNPQL EIK-DIPQPELDAKAV----------IDKMKGLIAR--GFSWRSIAYRTVNDIERAGALG VELVLMGN-LA----------GKG-------------ERKRKVRIA-------------- ----KGYMKKVGEQA-KLVEFAIGTAYFKLGSIG-------------------------- ----------LRLRIV---------------RPGT----------VFPDHL--------- -------------DLK--------AFL---------------EARKAG-VE--AAT---- ----------------------------EGP----------------------------- --------VEVKAA-----------APGAGESVETP------------------------ -------------------------------SKTM------------EEKQGAEE--KPK KESKP------------------------------------------------------- ------------RGRKKAKQPSTLKDED-------------------------------- ----VKEAPASPEKTP-------------------------------------------- --------------------------------APVQ------EKNVE------------- IVKNVQGGNAV-----------------------------------MKVSVYSLDGKKGH EVELPRVFQT-AIDENLIKRAVLAVETTALQPHAPYYRSGMQNTAEYEGARH-L-PTSER SINIGRARRPR-MKN-RRGLIAGRVTSIPGSVGGPEAHPPK-----RDKKLVERINKKER RKAIESAIAATMNASLVKKRGHAFD--EK-I-FPLVVEAKLEELKKTKEVVKVL---GAL NVLNDVVRAKKA-KQVRAGKGKRRGRKFKRRKSVLIV-V-S-GKTP-------------- -----IFKAARNLEGVDIVQAKQLNAALLAPGTHAGRLTLWSEKA---LRALEGSA---- ------------------------------------------------------------ ---------------------------------------------MAHSPT---YKVPFR RRREQKTNYAKRLALL-KSRELRMVVRKTNNQVIVQFVEAREAGDHVHAAAQSAEL-KKY GW----KLHGGNIAAAYLTGFLAGGKAKKT-GVSKAVLDLGLVTPVRGSRVFAALKGAID AGIHIPA--SEAAFPK------PERLKGKHVEAW----LSKNP-GLGNAFSRYKK--EGV DYSKYSSYVEAAKAAIEQE---------LK------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAI-NASVVRSLTQFSTCTCADNSGA KEVYIISVLN--RRTRKRMNPKAGIGDLVQVVVSKGKPEMRKK---VELAVVVRVKKEYR RLDGVRIKFEDNAVVLVDEK--GLPKASEVKGVVAKEVGE-RWPKIVGIASGVV---MTS ----------------------------------------PQNV----------AC---- -T----DSKCAV------------------HGHLKVRGNVFVGRIVSAKAARTAVIERTQ TIYIPKYERYKKVRVRQAVHNPECMN--AKENDIVRVGETRKISKTKAFAVLEV------ ----------LG-SAK---------EIEREDEVRHRRE----------RAKESMRQSQKD AEMQKA-----GDHT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAAKDFSFRGKTLE--------------------ELQALEVNELLPLL TSRARRSLKRGF---------NKKLLQKVDRALGMK-KAGKDP--KPIRTH-LRQFI--- ------ILPKM----------------------------VGLRFAIHKG--------NTF E-----------ITEISPEMIGGY----------------------------LGE----- ----------YQLTR-KRVTHGK------------------------------------- -------------AGIGA-TK-------------------------------SSSAITAK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLTSPNFTVLTSICGKILDVAQRTGVKHSGSIPLPTKKLVVP TRKSPCGGGT-------ETYEHWQMRIHKRMIDL-EADERTLRRILRVEIPEDVHMEIEL KENK-------------------------------------------------------- ----------------------------MSFNEMPIHEKRVF-MSCHLSKALRKEL---- ---------------------GRR-ALPVHKNDTTKVMTG--AHK--GFSGKVSRVDRES GTVFIEKLVRRKADGT-EIPLS----------VRTHKIMLVELDSK-------------- ---------DER-RL-----------------------------------KRKKRASR-- ------------------------------------------------------------ -----GTAEEKGSGKKEEGIRHGK------------------------------------ --------------------------------MG-LRPGHCYR----------------L QKKPAYTRLAVTVP--DRNYIGAS-PGIKTHQFNVGNP----LKDFTH-LVNLVADESV- -QIRDNSIEATRLIITKFL-SRKLGKE-GFFLKIRVYPHMILRENKQAQ-GAHADRIQKG MSHPFGKPVGRAARVRP-GQVLMSILV---D-KENIEIAKTAILRARPRM--TTKLHAE- ISTDVQSIGTKPRKMTEEKVEEK----AEETKEGEAAGTGEGAEAGKEGGAKTETGKENP T-GKAPAG---KAP----AGKEAAPKKEDKKEKKK------------------------- -----------------------------M-SLV-DPLADALVNIKNHESAAKKMCVIYP ASRLLGEILRVMHEKGFIEGFERIDDGR-QGLYRITL----------------------A GKINECKAIKPRYAVKKDGFKKFEK--------------------RFLPSRDLGVLIVST PKGVMAHDQTKEQNIGGRLLAYVY------------------------------------ MKMSEV------------IHNVEIPEGIQVDVQEH----AVIILS--KDGKSLRKRFV-E R-G----LHLEK-KGNG-VQVKLH----KDT---RRLRALKNTIEAKVNNMIVGLEKG-F TYKLAVVHAHFPITLNKK---GNS--VE-INNYLGEKNPRHARIL--EGVDVQVKGK--- ----EILVKGMDVDAVGQTAANLEQATRQTK---KDPRV----------FQDGIYLVERS EGM--------------------------------------------------------- ---------------------------MARLHKPRSGSLAFYPKKRASRQLQSFRTF-S- L-EAQK---EARPLAFLGYKAGMVHVIAKDEHKKSPSF--GQEIVVPSTVIECPPLNVFG VRFYAIE--NNA-LT---CKGEVRAEKLEKH-----F-----MKNL-------------- ---P---------------KGQSKGKKGE----EKKREERK---RKTFADFEPM------ ---KN--ALAHVRLLVHSNP-----SQTSFGRKRPDVTEIHLTGTL-E---QQFEYARQK LGQ-EIRVSEVFKDHSWVDVKSVTIGKGTQGPVKRFGVKTARP--KS-DRQRH--VGSL- GPIN-PSTVA-WTVARAGQLGYQTRTEYNKKIIKIGSP-SDAP--LFTPKAGFTNYGTLS GDFVLLSGSVPGPVKRAVSLREALR-KPHHDRLALG------EATFVSTQVGK------- ------------------------------------------------------------ ----MVKKEFQLS--------------------------------------GTGTASHLA R----------------------------------------------------------- -----------AFASNQP-VSFKYSVEICREI--KGKKLDKAVSFLENVQEQKAFLPLRR YNK-KVGHRK-----GNSYSFVKS-GRYPKNACRAWLKLLESVKANADYKGL-NADQLLV VHAFASIGFRRYSHQN-------Q--GRISGKRRRRKS-THIEVIV-------REGR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRLILQR-------------RGKGSPTFTA-PITGT- AALKF--IPLDEKQKTGVLKGE----VIDLFDDPTKNAVVSEIVFENNLH-EYVVAAEGL SVGQKVEYGK-------------NAA---LNIGNVLPLQYILEGVPVFNIEKNPGDGGKF VRTSGLYGLVVSK-EP--A-RIFVKMPSGKLMEFKPNARACIGCISGGGKREKPLVKAGK AFYARKAKKKWFPTVRGVAMNAIDHPFG-GSQH-HA---G-K----SKSTSRHAAAGRKV GAIASSRTG-------RRKKN--------------------------------------- ----MTTPN----------------------------------------------PMQRV FIAKVTLNMGVGQTGEELKRAEQILQRV-SNH-KTVQTICK--V--KQPEWGIREGIPIG VKTTLRGG-HA-SAFLKQALQANGNELNARSFDRLGNFGFGVKEYIDLPGAKYDPKLGIR GLDVLVTLEKP-GYRVKKRKVRTRPIGKRQLVGREEAIEFVKKEFGVKV-V--------- --- >Bin312_genes -----MV-LNKR--KKNTR-MRAKT--THGYGSMKKNR-GAGNRGGRGM-AGTGKRADQK K---------PSILKEY-------------GSS-----Y-F--G-------KR-GFNNP- -RKI--KS--KF-----L-NLEYINK----KLE----------KK---------EGDFFI FD--ASK----YDKIL----SKGDLTKKV-KIKC---KSFSKSAINKIKNAGG--EAI-- I---------------------------CS------------------------------ ----------------------------------------------------------MI E--------------------RKIIEKKLKEYAI----------------KKHVESKVGG GGGYSHTDIR------KTPLGENIIIHTSRPGMVVGSKGKNIRALTEELKRKFKLENPQI KVN-EIEKPYLNPETI----------AREIVSSFERFGPRRFTFMGYKMLNNIMNAGARG TEIILSGRGI------------PS-------------VRSKTWRFS-------------- ----AGHLKKSGYISEEKVLKACKVAHLKSGSIG-------------------------- ----------VKVNIL---------------TPDV----------ELPDEV--------- ------------------------K-I------------K-E-------IKEDP------ ------------------------------------------------------------ ---------KEEVK-----------EEVKEEVK--------------------------- ---------------------------K----------------------ETKTPKKEIG KVPT-------------------------------------------------------- ------------AKELAEKKET-------------------------------------- -----KSDKKGKE----------------------------------------------- ----------------------------------DG------NNKKK------------- ----------------------------------------------MKADIYNLEGKKVK EIELPSIFSE-EIRADIIKRAVLTLQASRRQRYGTNPTAGMDYSAKLSRRRK-A---YRG GYGKGTSRIPRKVMLRRGSQFIYVGAVVSGTRGGRKAHPPK-----AEKIFEKKINKKEN RKSIRSAIAATVNKEYLIKKGFTSL--E---SVPLIIEG-LEKLSKTKEIIELF---KKL GLEKEITRASK--KTIRSGKGTMRGRKYKRVKGPLVV-V-S-KKEQ-------------- -----LSKACSNLSGFDISTVKSLNAELLAPGAEPGRMVVWSLDS---INKLEKEKLFTN ------------------------------------------------------------ ---------------------------------------------MLKSKI---YTVAFR RKRERKTNYKKRIKYI-SSNKVRIAIRLSNKNIKIQGIKFNENGDFVLATITSLEL-KKL GW----KGSINNIPSAYLTGFLFGKKVKDK--FNEGIIDIGLKSITNGAKLTAAIKGIVD SGINVPH--SKEIFPK------EDKICGKTISEFFKKLKESNQ-EANNQFSKYLK--GGL NPEDLLKNFEEVKKGI------------LGEK---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAI-KAKIPRCIVRGSKLQVCDNSGA KIAYLVSIKG--SKTSKGRMPAAGVSDLVKVSIIKGDKSIRKQ---LVPGIVVRQTKEYK RYDGTRIKFKDNAMIICKDEK-GNPKGTLFKGPIAKEATE-RWPAVGKLAKIIV---MKK -------------------------AKNIG---IE-VKL-PSKE-----------C---- -N----DKNCPF------------------HSNLKIRGRVFVGKIVSKDTHKTAKIEWVR IYPLKKYERIEHRTSKIKVHNPPCLD--CQVGDTVKVVETRPISKTKKFVIVEK------ ----------IK------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAK--ITFKGKTEE--------------------EIANIALQDFVKLV PSRQRRSITRGF------TDSQKILLKKIDASKKG-----TYK--KNIKTH-CRDMI--- ------IIPQM----------------------------LGSTIFIHNG--------KTF S-----------PIEINIERLGHY----------------------------LGE----- ----------FVDTR-NKVKHSA------------------------------------- -------------PGIGA-TR-------------------------------SSAYQSVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MRKARVNLACTEIEKLNTICDAIVDIAKKTKIPVKGPIPLPTKKLKLT TRKSPDGEGK-------ASWERYELRIHKRLIDL-GVDERALRLVMRVHIPEGLNIEIDL LE---------------------------------------------------------- -MKS--IFSTS-----WKSSKQPRKQRKYVKN-APKHIKSKF-MSAMLSKELRTKH---- ---------------------QKR-NIPIKKGDKVKVLRG--QFK--GKIGKVTKVDLRN LKINLVGVDLMKKDGT-KVPYP----------IHPSNVMITELNLD-------------- ---------DKK-RK-----------------------------------KILERK---- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MASLRKGKCYREV--------------- -K-RAYTRKSKYK---KKGYIKAP-TPIKIVKYHMGNL----KREFSK-TLKLVSTDKY- -QIRHNAIESVRVVINRNL-SRKFGIE-NYHFHINIYPHHILRENKMIT-GAGADRMQSG MKHSFGKAMGSAAQVKK-GTTLFTVMV---D--ENVEFVRGVLDSTRSRL--PG--AV-- ---------------------R-----VV-GPA--------------------------- ------------------------------------------------------------ -----------------------------M-SLN-DPVSNAMSQIWNSEKVHKKNCIIKN SSKLIKAILEILKENKYISSFKEVSTTR-GEHLEVEL----------------------S GTINQCGVIKPRFSLKKGEYEKFEK--------------------RYLPAKDFGIIIVST PKGLMVHSKAIEKGTGGKLIAYCY-----------------------------------M LRLD-I------------KDRVDIPEGVEVNLDTL-----KIKIK--GPKGEIERRIF-Y P-G----LKVKK-EGSS-IILE---SN-KVS---KKEKMFLKTTEAHIKNMIYGVTEG-F TYALKICSGHFPMTVIHE---GKH--II-IKNFLGERVPRTAEVL--EGVNIEIKKD--- ----IIELSGCNKELVGQSAANIERSTRITN---RDRRR----------FQDGIYITEKA GITL-------------------------------------------------------- ---------------------------MAKRHKPRAGSLQVWPRVRSKRIYSSIGAV-L- K-DD-----SQKITGFAGYKAGMTHLIEKDTKSTSITK--NLEVFVPITIIECPSLKPFS LRFYKNT--PYG-LK---IVSEIPSEKLDKE-----L-----NKKI-------------- ----TVP---K--------K-QKD-----------------------KEFPK-------- -------EYDEIRLTVYTQP-----KLTGIGKKKPEIFEIPLNGD--------LEFAKSL LEK-EVKVSEIFKAGQYIDIHSISKGKGFQGPVKRYGISLKSH--KSEKKRRA--PGNL- GPFT-PRKVD-WRVPQHGQHGYHKRTEYNKLIYYVGS---DPK--KINQIGGIKRYGDVK NDFVLVKGSIIGPTKRLIIFTKSIR---D----KKD-TGAQ-EIVEISTSSKQ------- ----------------------------------------------------------MV ---EKKEEKKKTI---------------------------------------EDKKEHFA S----------------------------------------------------------- -----------VNVKNLP-ISTKQTIEIAGFI--RGKNLKKAKSLLSQVLEKKIAVPFKR YNR-DVGHKP-----G----KIAA-GRYPKKATEHILILLNSLEANAENKGL-NVDNLKI SEIMVNKGSNQWHY------------GR--MRRRKMKR-TNVKI---------------- ------------------------------------------------------------ ------------KTIEIEK----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRLIQQR-------------RGRGTPRYRSPSHNFI- GAILHR-P-YDDFEKSGIIKGK----IVDIIKCPGHSAPLAVIEYENNDI-STMFASEGI YTGKEITSGY-------------LSK---PEVGNIIPLKNGKIGTTFFNIESDAGDGGKY IRAAGTFATIVSK-TR--G-KIMLRMRSKKIKEFDPNCRAVVGIVAGTGVRDKPFLKAGK KHFMMKARNKLFPRTSGVSMNAVDHPFG-SGRGRHI---G-K----PKTVSRNAPPGRKV GSVSSRRTG-------KKK----------------------------------------- -------------------------------MN----------------------KMKEI RIEKITLNMGLGEAGEKVKKATKLLSTI-SGS-KPICTKSN--K--RIPTWGVRPGLELG VKVTLRKK-KA-VELLKRLFAAIENNLNPKSFDKEGNFSFGIPEYIDIPDVKYDVAIGIV GLEVAVTLERP-GYRIKKRKFKRSKIGKKHIITKNEAIEYIKNQFNIEI-GGEEK----- --- >GCA_003694385 --------MMRR--KKNTR-QRGTQ--THGWGSMKKHR-GAGHRGGRGA-AGSGKRGDAK K---------PRYWKD---------------AE-----R-Y--G-------KH-GFAS-- GTKR--PL--VT-----M-NIGHLAS----ILGRLEE-EGLA-QK---------EGATLT VD--LSRLG--VERLL----AAGSIHTPL-VLKV---ASATKRAVQKVEAAGG--TV--- -----------------------------QNT---------------------------- ---------------------------------------------------------MAV E--------------------RKFVQQKLKEFRI----------------RQFVSGQL-S RVGLSDIKLQ------RTPLGDKILVKASRPGLVVGRAGSNIQKLTEALKTEFRLENPQI EIE-EVQKIGLDANII----------AEMIVNSLERFGSQRFKGVGHKSINEVMSAGALG VEILISGK-I------------PS-------------QRARTWRFY-------------- ----QGYLKKSGDVAISGVNVAYKTAVLKTGAVG-------------------------- ----------VKVSIM---------------PPTT----------KLPDQI--------- ------------------------L-L------------T-EPAAPT--ME--EVTEP-- ---------------------------ETKA----------------------------- --------EMEAVV-----------QEAEAAQ---------------------------- ---------------------------SESKD--------------------------AK SENAAKP----------------------------------------------------- ------------AKAK----QPVK------------------------------------ ---TKQPAKKQPKQQAKKSKPKK------------------------------------- --------------------------------AA--------TTKT-------------- ----------------------------------------------MKLAILNAKKEHKG DQELPKQFGE-SVRPDLIARAVRALQAQRRQPYGADPRAGKRASAELSRRRR-K---YRG SYGSGISRVPRKILTRRGIRMYWVGAFAPGTVGGRRAHPPK-----AAKRWVQKLNVRER RKAIRSALAAVMNRDLVVARGHRPP--Q---SYPFILDSSIELIAKTKDAEAAL---STL GFDDELARCER--TKVRAGKATMRGRRKKRPTGILLV-VGE-KNVP-------------- -----LIKAAGNIAGLEVVHVRALNTELLAPGTHPGRVTLFTTSA---LKIMQDEGLFLD VGKRRLSAQRKEPEAP---------PAKASGGVTRSQEPKAQQKAPQKVPPTPKQAMPKQ ATTKQAARQATAPEAEETAPPASKPPRKPSTQPPTQQGEAA----MVNAR----HILGYR RKREGRTNYKKRLALL-KSAKPRLVVRTSNRYVQVQLVTYEPDGDKVIVGLSSKFL-QQH GW----KGNGKSLPAVYITSQLLAKKAVEK-GFTEAIADLGLQRHRAQGRLAAAIKGAID GGLSLPA--DPSVFPP------ADRLAGKHLAD------------------------NGV -------MASTVAKKLGVE---------LKGDAA-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAV-KAKMTQGIPVGALIATCDNSGA KLLKIFSVVG--QKTRKGRVPAAGVGDLVMASVKKGRPDMRKQ---VVHAVIVRQKRPYR RPDGTHVSFEDNAAIVLKDDK-GNPKGTIFKGPIAKEACT-RWPAVAKVASMIL------ ------------------------MEKK-------------------------------- ---------------------------------IRTHGRTFTGVVTSDRMTRTVTVTWER RHYVPKYQRYERRFSSVKAHNPDTID--AKKGDTVTIMETRPLSKTKHFI---I------ ----------IK---------------------------------------------KH- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MARKEFTYRGRTVQ--------------------ELQEMSMDEFAHLL PSSERRKVSRGF------THDEKSLLKKLAKRDK-------------VKTK-SRAMI--- ------VLPSM----------------------------VGKTIMVHNG--------KEY V-----------AVTIQAEMIGRR----------------------------LGA----- ----------YALTR-KPTKHSS------------------------------------- -------------AGVMA-TK-------------------------------KEKK---- ------------------------------------------------------------ ----------------------------------------------------------M- ------------QQKARIKLASTDIDKINEVCKYIQDIADKTGVVMRGPIPLPRKVLKIT TRRSPDGEGK-------ATWERYEMRIHKRLIDL-GLDERALRLIMRVPIPEGLQIEIEM I----------------------------------------------------------- -MKQ--AHSTK-----WKASVQPRKQRKYLHN-LPYHRQGSQ-LSVHLSPALREKH---- ---------------------KTR-ALRVRKGDKVRVLRG--THR--GKEGIVDHVDVRN ARIHVSKVEHAKREGG-TAPYP----------LRPSNCMLIQL-VE-------------- ---------DKR-RFA----------------------------------KKEEKK---- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MAKLRKGVAYRRL--------------- -E-RPYTRKSKFR---AKSFVRAT-PNNLIVKYDMGDT----KRDWPV-KVRLLSKAPV- -QLRHNALESARKTCNRLL-ETKLGKN-GYHFKIKVYPHHVLRENPLAS-GAGADRMSTG MKMSFGKSIGLAAQVRK-GQTILEIGC---E-EKNLGVARLAAERANHKL--SVGTRI-- ---------------------E-----VIGA----------------------------- ------------------------------------------------------------ -----------------------------M-SLN-DPLANVLSAIKNAEQRGQREVLTKN NSTLIRRVLDIMKANDYIADYEVIPDSR-GGSLRIIL----------------------K GSINDVGVIKPRYQIRHKSFERFEK--------------------RFLPARGFGLLIVST NKGLMTHMQAREQNIGGTLISYVY------------------------------------ MKLEEI------------QETITLPEGVTASYEQEH---HTLTLK--GEKGELSRVFF-H P-R----LLLRV-DGQT-ITLT---SR-KAT---LREKKTLFTFASHIRNMVTGVSEG-Y TCKLKVCSGHFPMSVAVK---GDR--FE-VKNFIGEKVPRTLTLK--PGADVAVNGT--- ----EITVTGCDKELVGQIAADIEQLTRRPG---FDSRI----------FQDGIFIVEKA GKHT-------------------------------------------------------- --------------------------------------MQVWPRKRARRPYARVRSW-N- R-A------EKGLLGFAGYKAGMTHVMAVDTGKNSPTK--GETIAVPVTVLECPPLRIYS VRAYTED--AYG-KH---VKTEIVVGT-DKF-----L-----ARKL-------------- ----QTK---K-----------TR-----------------------AEQLKELK----- ---PE--EYADITIIVATQP-----SKTGIGKKKPELFEIALGGSN-E---EKLAWITEH VGK-DIPVTEVFKEGDYLDTHAVTKGKGFQGPVKRFGIGFKSH--KSEKGRRN--PGSL- GGWSGQQHFM-YRIAHAGQTGYHLRTQYNNQILKVGE---DPK--EVNPAGGFLRYGEVK NPFVLVRGSVQGPKKRLVTLVKAVR-PKE-Q-RSLP------TVELISTRSQQ------- ------------------------------------------------------------ -------MAYAFA---------------------------------------TFKKETMA R----------------------------------------------------------- -----------AQMRDAP-ISFKQAIELARNL--RGMMSDKAERYLENVIALRQPVPYTR FTE-GAGHKR-----G-----IGA-AKYPVKTAKAFKELLKAAVANAENQGL-GT-PLKI IHLLAQEGSRPLRP------------GR--KRGTLMKR-TSIEIVL-------AETDASR ---KQAKKPKPRSKAASPPPKAR--------------PSPGPAKAAQPRSPAKQPST--- --------EKPVTVEQPQAQAQPEKPAPPRSAPGAEQKIS-------------------- -----------------------------GEEKTSKPKSKP--------ETAASEEKTDE ------------------VKKDGR------------------------------------ ---------------------MGKNLIQQK-------------RGKGSSTYRRHSFRAV- GKARV-----QDRG-----SAI----ITDIVHSKLHTAPIAKVCYEDGEE-GVIIAPEGV CVGQRIVIGS-------------EAP---LELGNTLPLKNLPEGSLVYNIEAQPGDGGKF VRASGGVARIVGK-SL--A-GVIIQLPSKKRKTFNPACKASLGVAAGGGRREKPFMKAGR KHHYCKAKNKYWPKVSGAAMNAVDHPLG-GKRSGRK---G-R----PTIVPKNAPPGRKV GMLRPRHTG-------RNK----------------------------------------- -----MEQK-------------------TITMN----------------------RMRAI RVEKLTLNVGAGKDQSLMQKAERLIEQL-TGI-KPVKTRTQ--K--RIPGWGLRPGLPIG LKLTLRGK-QA-QELIPRLLAAKGLTLKPSNVDAAGNISFGIPEYIDIEGAKYDPEIGII GLQVCITLERR-GYRVKRRRIKAAAVGKHHRIKPEEAMQFMQEQFKVRF-ER-------- --- >GCA_009649835 -----MK-KNV---TK----FRGSR--TCGGGTHKNRR-GGGSRGGRGN-AGGCKHHFVR NYM-----KGM---------------------------A-Y--G-------KH-GFKRPQ KVLS--NK--PI-----V-NVGELDE----LAEQLVQ-YGEA-HK---------QGDIYH IN--LAELEYPIVKVL----GNGRITKPM-AITV---SECSARAMSKIEEAGG--SIE-- EYVPPL----------------------KEVDIEPEETRGP-DV---------EDI---- ---------------------------------------------------------MGI E--------------------RKFVQDGLTKARI----------------NEYFTKQL-E RAGYGGMVIN------RTPMGTQITLFAEKPGMVIGKGGKTIHRLTSDMSYVYNVDNPQI DVQ-EIKVPELNAQMM----------ANRLANALER--GWYFRKAGHNMLRRIMDSGALG CEIVLSGK-F------------TG-------------PRSKVSKMV-------------- ----EGYIKHAGKPAEELVDTGFATAVKKLGTIG-------------------------- ----------CRVRIV---------------QPGT----------ELPGKFYMLKDEKPA APETPEPE----KKAK-EGI---KE-V-------------LEKAPE---EPGMKNI---- ------------------------------------------------------------ ----------RQVG-----------SVWEHKHDELDW----------------------- --------------------HTMSVPHPAPAAVPA------------TEVAEEEPVTAV- -EAKPTVEAESTVEVESSVGVESTIETEP----------TVGAEPTVET------V---- ---------ETPVVSPDIELPEGEQTRINDG----------------------------- ----VEEHKHEGY-------------------------DYWHPS---------------- --------------------------------SRTH------KNKGD------------- --------EE-----------------------------------MSKAKIMDITGAPKG DIELPAVFDE-IYRPDLIKKAVLAAQANRLQVYGPTPYSGMQTSAANWGPGR-------- ----GVARVPR-IKT------GNRVARITQARGGRKAHPPK-----VEKDYSEKINKKER YRAINSAIAATANPELVRKRGHRFD--A---ELPIVADDAFQDIKTTKEVVGFM---EAI NVYDDVIRAKNG-KHIRAGGGKRRGRKYKKPKSLLIV-I-G-GDNG-------------- -----IRRAARNLSGVDVINVNRLNTELLAPGTHAGRLVIWAESA---IKVLGEE----- ------------------------------------------------------------ ---------------------------------------------MATGPR---YRVPFR RRREGKTDYRQRLHLL-ISKQPRIVARSSLRHMKLQLATPKPEGDNTWVHADSSEL-KKY GY----TGSTGNTPAAYLTGLLFGYKAQAA-GYENAILDMGLQVSSKGCRVYAALKGVVD SGFEVPH--DPAIFPG------ESRIKGEEIMEYT------------------------- -GTDIPAQFEEALTKI------------KNEFGED------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MIGM-KAKIPRALNAGARLDCVDNTGA RQVEIISVKK--YRGVKNRHPKAGIGDMLVVSVKKGTPEMRKQ---VLNAVVIRQKKEYR RPDGLRVSFEDNAAVITDLD--GIPKGTEIKGPVAREVAE-RFSKIATAASIIV------ ------------------------MTRDIG---LD-INASPDEE-----------C---- -N----DINCPF------------------HGTLPVRGQVFTGSVVSSKMDKTVVVKRTF EKLVTKYERYEKRQSKMHAHNPPCIN--AKEGDVVKIAECRPLSKTKKFVVIEV------ ----------AK------------------------------------------------ ------------------------------------------------------------ ------------------MAKKSTT----------------------------------- ------------------------------------------------------------ ---------KLPKRKGEFTYRGKTLR--------------------DLKKLSLEEFAQLL PARQRRTINRGL------GDEHKKILNKINEGDTT------------IKTH-LRDMI--- ------ILPEM----------------------------VGLNLEIHNG--------KSF E-----------KVEVIPEMLGHY----------------------------FGE----- ----------YSFTR-RRVSHGS------------------------------------- -------------AGVGA-TK-------------------------------SSKFVPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------PQKARIRLSGTSPSTLDTLCNQVKSIAEKTGVNISGPIPMPTKKLVVP SLKSPDGEGT-------ATWDHWEMRVHKRLIDL-DADERALRQLMRLQVPKDISIEIVL TT---------------------------------------------------------- ----------M-----KIESKQPRKQRKARYN-ASLHQRQKL-MSAPLSAELKAKY---- ---------------------NKR-NLPVKLDDTVMVMRG--DHT--GTEGKVELVDLKR GTIIVEGVSVAKADGT-EVPRP----------VQPSNVMITKLELD-------------- ---------DDI-RK-----------------------------------LTLNRGGE-- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MG-NRPAKTFRNYN-------------- SR-RAYTR---------RKYMGGV-PGSKVVHYDMGNV----KGDFPI-KVSLVAKEAC- -KIRDSALEAGRITANRLL-VKNLGTQ-NFHVKLRVHPYQVIRENKQAT-GAGADRVSQG MRQAFGKATGIAARVRA-GQKVFTISV---D-KEGFPIAKDALRRCGHKL--STPVSI-- ---------------------V-----VDEGQKLIN------------------------ ------------------------------------------------------------ -----------------------------M-VLL-DPLADALSTIINAESTGKPDCIIHP ASKVIGNVLKVMQDIGYIGNYEFIDDGK-SGMIKVEL----------------------I GKINKCGVIKPRSSVGYHDFEKWEK--------------------RYLPARNFGTLILTT PKGVLSHSEARSRVVGGQLLAYVY------------------------------------ -MPKDL------------KRTLDIPEGVTVVLEGN-----TISVT--GPRGSSVRELW-Y P-G----IVIAL-EEKQ-VTVD---SP-NPR---KKQSAMMGTITSHINNMIKGVTNG-Y TYRMKIVYSHFPIQLKVV---GDH--LS-IGNFLGEKKPRKAKIQ--GDSKVETKGD--- ----EVIVSGIAIEDVGQTAANIQQATKIKR---FDPRV----------FQDGIYVVEKT TA---------------------------------------------------------- ---------------------------MANLHRPRRGSLAFSPRKRAKSQVPTMRSW-S- E-GNK----EPKLGGFAGYKVGMTHVIMMDDKPKSLTE--GTEISVPVTVLEVPAMKIAA IRVYGKTG-PYG-TR---TLGEAWSGDLDPT-----L-----DKKL-------------- ----FIP---KKN------NPEKA-----------------------LERIGKL------ ---VEEGKVANIHLISYTLPS----LIAGIPKKTPDVMEHRIVGGDMA---TRLEYATSL IGK-SVDVSDVFNTGDMIDVSAITIGKGTQGPVKRWGINLMKH--KHSRQGSLRQIGTL- GPWN-PSRVS-WRVPQLGQTGYHQRTEYNKRIIKIGE---NSE--EVTPNGGFLNYGEVS GNYMLLKGSVPGPKKRLIRLRPAIR---G-D-KQQ--IGAP-QVSYISIESKQG------ ------------------------------------------------------------ ----MARIAYSAQ----------------------------------------ADPDTTS R----------------------------------------------------------- -----------AMGHELH-ISPRHSREICRAI--KGMQTGQARKYLEDVTVLKQAVPFKR HND-SMGHRR-----G----PMAA-GRYPQKAAKEFIKLLVNAEANAEYKGL-DSDHMKI THIATKQGRVIRGYRP-------RARGR--SSPKNTET-VNIEMII-------QEVQ--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRIISQN-------------RGKGTPTYRAPSHKFK- AKLKH-----IKVDRDETVKGE----VIEILHDTARSAPIARVSLENEEE-RLILIPEGI AVGQEIACGI-------------SAE---IQPGNTLPLREIPEGILLCNIENKPGDGGQL ARSSGVYAVLIAH-DV--G-KTVVQMPSGAMKWLNPGCKATIGVVAGGGRVDKPFVKAGK KYHKLKTRAAKYPRVSGVAMNAIDHPFG-GGGWQHP---G-R----PKTVSRRAPPGRKV GSIAARRTG-------KR------------------------------------------ ----------------------------MSENN----------------------VMTIP RVDKVTVHIGVGESGERLNKAEDILSEI-TQQ-GVVRTKAK--R--TLQTFAIKKNEPIG CKVTLRGK-LA-ENFLKTSLDIIENSLRESQFDDTGNFSFGIEEHTDYEGMKYDPNIGIF GMDVAVALIKP-GYRIGRRKIGKRKMPNSHRMTKQSAVAFMNEHYGVEV-VA-------- --- >Bin305_genes ------M-DYKR--KKKVK-QRGTK--THGWGAMKKHR-GAGSRGGRGM-AGTGKRGDAN K---------PRIWKD---------------KK-----Y-F--G-------KH-GFTS-- -KGY--GV--PS-----I-NVSDIEK----DIDEFIK-KGLA-KD---------EKGVFV VN--LADLG--YEKLL----GKNKVTKKF-KITA---LKATKKAIEKVKNSNG--EVI-- I---------------------------LSEKVEKEQTEG-------------------- ----------------------------------------------------------MI E--------------------RQIISQKIKEYQI----------------QEYIANSL-K RVGHSHTKLQ------R------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MKTTVFNISRVELK KKDLPSQFNE-EIRPDIIKRAVVSVLNSRRQKYGASPGAGKRASAELSRRRH-K---YRG SYGFGISRVPRKILSRRGTRMSWVGAFAPGTVGGRRAHPPK-----AGKIWKKDVNKKER RMAIRSAMSACVIKDIIKARGHIIP--D---DFPFLVEEKFENIEKTAEVKKIL---EKL GFKEELERVSN--KKVRAGRGKSRGRKYKKIRGVLIV-V-S-KDCG-------------- -----LLKGARNIEGAEIVVVDKLNAETLAPGTNVGRLVIFTEPA---VDRIEKEQLFTN SPIIKKQEEKIEKK-----------------KEVKEKKETKVEVKKEP------------ KPVK----KSVKKSK------------------------------MKKTK----HTVRFR RKE--KTNYKKRLKIL-MARKTRLVVRKSLKNITIQMIKYEPEGDKVLISVNSKKL-GDF GW----KFSKKNISSAYLAGLFAGIKSMEK-GINEAVLDMGLHSPVKKSKIYAALKGVID AGVKVAS--SEEVFPS------EDRIKGKHISDYHK------------------------ -IKDFEKIFETTKNKILNGSGKPKVSGTLKNEAVL------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------EGAK-------------------------------------------------- ------------------------------------------------------------ ----------------------------IFKGAIAKEASE-RWPGISKTARIVV?????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFRYHGKSLE--------------------EIKSMGLKEFAMLM PSKQRRRIIRGF------TEKQKNLLKKIRENKS------------NIKTQ-CRDMM--- ------ILPEM----------------------------VGKMIKVHKG--------NKY V-----------PVMIEEEMIGHL----------------------------LGE----- ----------FVLTR-SNVSHNA------------------------------------- -------------PGVGA-TR-------------------------------SSASVSVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLASVDIDKINEICGSIKEIADKTGVEMRGPIPLPTKKLKLT TRKSPCGDGK-------ATWERYEMRVHKRLIDL-GIDERALRLVMRVHIPEGLNIEIEL LDV----MARNIKNSQDSG---------------------------------------VI IMKT--KFSTA-----WKSSKQPRKQRKYTHN-APSHIKSGF-LGSHLSKELKKKY---- ---------------------NKR-SIRVKKGDKIKIMRG--KFK--GKTGKVENVDVKR SLIYVEGIQISKKDGT-KTKQG----------FHSSNMLITELNLD-------------- ---------DKK-RV-----------------------------------NKLGKQEK-- ------------------------------------------------------------ --------KEKKNPEKSKISGVPKTGGF-------------------------------- --------------------------------MAKLKKFSAYRNL--------------- -E-RPYTRISKFR---KKSFIRST-PPSKIARFESGDV----NKKFEY-KVNLMSKEAL- -QIRHNAIEAGRQTCNRLL-EKMLGKN-GYFFKIRIYPHHILRENPLAA-GAGADRMSTG MKKSFGKAIGSAAQVKI-GQVLATVSL---D-KQGIKVGKEALKKMGHKM--PCSCRI-- ---------------------E-----AVEA----------------------------- ------------------------------------------------------------ -----------------------------M-SLN-DPISNTLSKIMNAERVGKKECEVKS -GRLMKQILDLLKDHLYIGAYEEVEDGK-GGILKLNL----------------------L GNINKCGTIKPRFSVKKTDFEKYEK--------------------RYLTAKDFGVIIVST PQGIMTHTEAKKKGIGGKLIAYCY------------------------------------ MKEKII------------EEFIEIPEGVEINTDNS-----NITVK--GPNGEVKRTLH-D P-K----IKIKI-EDKK-VKIY---SN-ETT---KREKRKIGTFKAHIKNMIKGTTES-H KYVLKICSGHFPMNVALN---NNE--FV-VKNFIGEKVPRVLKIK--ENVVVNIEDE--- ----IITVTGIDKELVAQTSADIETLTKRVG---FDRRI----------FQDGIFITEKD GKIIS------------------------------------------------------- ---------------------------MPSTRSPRKGSLQYWPRKRARRSYARIRTWFS- K-TT-----DPKPLGFAGYKVGMTHLMIKDNNERSLTK--GQNINFPITIIECPPIKVAS LRFYKNS--VSG-LH---AVFDVFAENLDKE-----L-----ERKI-------------- -----LN---K--------K-GNK-----------------------ITDVK-------- -------DYDDVRLVVYTQP-----KLTGIGKKKPEVFEVHLSGEK-E---AKLEYAKSV LGK-EIKINDVLEEGQQVDIHSVTRGKGLQGPVRRFGIGLKSH--KSEKHRRT--PGNL- GAW--TGGKM-WTVAQSGKTGYYQRRDYNKWLIKIG----EDK--EINPKSGFPHYGVIK NQYIFVKGSVGGSQKRIIIMTNALR---E-N-KKIP-KAAP-EIVYTNIN---------- ------------------------------------------------------------ -----MVYKYAA----------------------------------------KLGEENSA V----------------------------------------------------------- -----------AAGRSLS-ISTKQSVEICRFL--RKKKLQRAKNMLNDVIAHKIAVPYIR YYG-DVGHKK-----G----KIAA-GRYPEKASKEILKILESVEANAQLKGL-STGDLFI EHICAHLASRPWHY------------GR--QRRRKTKR-THIEVIV-------TEKKNKK ----QEKKIEEK-KPEVKEET--------------------TEKQNIVSKKPEI------ -----------SKAIEEKKQVVEEK----------EEV---------------------- -------------KEQ---------------PTEKKEEKKE--------TKVK------- -------------------KND-------------------------------------- ---------------------MGKRLIQQR-------------RGKGSPTYKSPSHRFK- GEIKN-----IRFGKE-NINGK----ITDLLKCPGHTGPLIEITLEKGER-KLIIAPEGV RVGESLEAGE-------------DVS---LKIGNTLLLKNIPEGTSIFNIENAPGDGGKF VRASGTFAKVITQ-LG--K-KVIIQLPSKKKKHFNSECRATIGTVAGSGRTEKPFLKAGN KYKAMRAKNKLYPSISGTSMNSVDHPFG-GTSSNHK---G-R----PTIAPKNAPPGRKV GMLKPSKTG-------RGGKK--------------------------------------- --------M-------------------SKELN----------------------PMRNI KIEKITLNIGAGKDSVKLEKGMKLLKNL-TNI-NPIKTFTN--K--RIPGWGLRPGLPIG CKLTLRKK-IA-KDMLTRLLDAKDFKLNNKQFDNLGNISFGVPEYIDIKDAKYEPDIGIM GLEVCITLERP-GYRIKKRRRMRKKISKNHQITKQDSMEFMKKEFNVEV-IEDDNE---- --- >GCA_003650585 -----MG-FHKR--KKSSR-MRGSG--SHGYGAKKKHR-GSGHRGGVGR-AGTGKRADSK K---------PSIWK----------------ER-----Y-F--G-------KQ-GFKRK- -NAI--QI--RA-----I-NIDDINK----KLERF---TEGV-KQ---------TKDGWE ID--LGQLG--YQKLL----GRGKPVGVY-FIKV---DYASRKAIEKIEAKGG--KVN-- VSTNFDR----------------GAVEEPKQKTEETEEQQEPKE---------KKEPKKS EGKG------------------------------------------------------MI E--------------------REIISRQIKEYQI----------------KEFIEDFL-N GAGYSHTEVK------RTPLGEKIIIHTSRPGLVVGRSGKNIKELTEQLKVKFDLDNPQI EIA-EVDDPNLNASIV----------AERIATSLERYGPVRFKSIIHKAVEASMAAGAMG IEVLLSGK-V------------PS-------------ARARTWRVS-------------- ----AGYLKKCGEPALENVDISYKIAKLKSGVVG-------------------------- ----------VVVKIM---------------P---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????----MPRKIK----VLGMK RKREHKTNYYKRLKLL-KGRRTRLVVRVFSRSILGQFVDYAPKGDKVIVGVNSISL-RDL GW----QYNCCNLPSAYLAGLMLGKKGLEK-GVKDAILDMGFHRSVPGSRVFAFVKGVID AGVSVPI--SEEMLPK------DSRLRGEHIAGYLKS-------APKAQFTRYKK----L KKMDIVKDFETVKGKI------------LDGK---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MVVKEFRYRGKTLE--------------------ELKQMSIKEFAQLL PARQRRSLLRGL------TEAQQKLLKALEKKE-------------APKTH-CRDMI--- ------ILPQM----------------------------VGRRIQVHNG--------RAF I-----------SVVIQPEMIGHY----------------------------LGE----- ----------FAMTR-KPVEHHA------------------------------------- -------------PGIGA-TR-------------------------------SSAALSVR ------------------------------------------------------------ ------------------------------------------------------------ ------------MPKARIKLSSIDIDKINQVCNEIRAIVEKTGVEMRGPIPLPTKKLRIT TRKSPDGEGT-------ATWDKFEMRVHKRLIDL-GMDERALRLVMRIPIPDGLNIEIEM IED----MTEDAE-------------------------------------------PKIY ALRT--TANREDQVADFIASNIVKKGLEVYSVIRAHGMRGYIFLEAKDRREAEEASFRVP YARGILPKEIDFKEIEHMLEHTQQSKMTIRKNDIVEIISG--PFK--REKAKITRFDKEK EEVVIELLEA-------AVPIP--------ITLSLDSVKVIRRDKE-------------- ---------EEG-EEESEQEET----------------------------ESSKKESR-- ------------------------------------------------------------ --------EDYGGPLAKTK----------------------------------------- --------------------------------MAKLRKFVAYRRL--------------- -E-RPYTRKSKYK---AKQFVRSF-PHVKIVRFEHGDR----TKSYDK-HLMLVAKESL- -QIRQEALESLRQTVNRYL-EKNIGKN-QYFFRLRVYPFHVLRENPLAA-GAGADRMSTG MKKSFGKPIGIAAQVKT-GKIICEAFV---T-KQNEEKAKIALERGSKKV--PGSYSV-- ---------------------K-----VEPHSGEIH------------------------ ------------------------------------------------------------ ---------------------------------N-NPIANMMSKILNAEKIGKRECLFAP ISKKSQKVLELLKREGYILDFKSISNQQ-GGYFVIKL----------------------G GKINKCGAISPNFNVKKDGYQVYEK--------------------RFLPAKGFGVLLVTT TQGIMTHIEAQEKGLGGRLLAYCY-----------------------------------M RITKDN------------TVEIEIPEGVEFSLDGH-----TIIAK--GPKGETKRNIY-D P-D----ISVEL-AQGK-VVLK---PK-RLK---KPQKKRMGTIAAHIKNMIKGVTQG-I LYKLKICSGHFPMSVQVR---GQE--FV-VSNFIGEKFPRVLKLKY-DDVKVEVNGD--- ----IVEVSGVDKERVAQTAADIEMLLKRTE---YDKRI----------YQDGIYIIEKD GKPVK-------???????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????--------- -----MPYKYATQ---------------------------------------QIEHSKSA V----------------------------------------------------------- -----------AVGLNLP-ISTKHAVEVCRML--RGLPVEKAKTMLKEVIAKKRPVPFKR YNR-DVGHKK-----G-----MAA-GRYPVKASRYILTTIESAESNAADKGL-LTEGLFI KSIIPHKAARPLRY------------GR--HRSRRTKR-THIEVVL-------EERVTKE ----EIKPVEKKEKPKEPKQE--------------------EEKQEGKLEEPK------- -----------GKVLESSKKEEPEK----------EKQ---------------------- -------------SEQ---------------PKRVKKQNKN--------KKKK------- ------------------------------------------------------------ ---------------------MGKNLIQQR-------------RGKGSHTYRSLSFRFK- GAAKY--P-PLTVGG----IAL----VADIINCPGHSAPLVELKLENRQK-CLVIGAEGV YVGQKVSLGV-------------TEE---LKPGDIAELGSMPVGTLVYNIEARPGDGGKF VRASGTSARITSK-LE--D-GVLVKLPSKKLKKFNPKCRATVGRVAGSGRVEKPFVKAGK MYHKIKAVGGVYPRTSGVAMNAVDHPFG-GSSSSTK---G-R----PTIAPKNAPPGRKV GKIRPKRTG-------KRK------------------------------??????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??? >GCA_013153895 ------M-VRRF--KKKSRYLRGWR--THSWGRVGQHR-KSGSSGGRGR-SGRHKHKWTW VLV-----YDPD--------------------------Y-F--G-------KH-GFIQPP PLVK--EW--RE-----I-NVGELDK----IVEDLAR-KGLV-EY---------RDGKYY VD--LLKLG--YNKLL----GEGKVTHPM-VIRT---PAATRNAEEKVRAAGG--EII-- LVREVL----------------------H------------------------------- ----------------------------------------------------------MA TG----GKR--------IPVYKKIIQENIKKWMV----------------KEFLEYKL-A KIGYIDCDIL------RSPLGTRIIIYAERPSRIIGRKGQNVRELQQLLATKFGIENPMI DVAPPKERPEYYAKVI----------ANRIAWAMAK--GVKFRRAAIIAIRQLVEAGVRG VEITISGK-L------------TS-------------ERARFEKFI-------------- ----YGTIYKCGHDAKTKVDKYIAHVLLKPGMYG-------------------------- ----------IEVRLL---------------PPR-----------RLSDEFY-------- --------------------------I--------------------------------- ------------------------------------------------------------ -------KTPEQVK----------PEEKPLEA---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---EAKPEQQ-------------------------------------------------- ------------------------------------------------------------ --------------------------MAIVPELNLEPWIKPRWVVPTRVKVFDLDGNPVG EIELPEHFRT-PVRIDLIRRAFLSAFTMRLQPKGTDPMAGKRTTAESFGVGL-------- ----GLARVPR-IKG-H---LWPRAAFAPMCVGGRRAHPPK-----VEKRIHERINKKEK RLAIRSAIAATAIPDLIRARGHIID--PV-VQIPPVVVKDFEKLQFLSDVKRVL---KRL GLWDDIERAHEK-TRIRAGKGKRRGRRYKTPKSILVV-V-S-EKCP-------------- -----VITALRNLPGVDVVKVDMLNMLVLAPGGQPGRLTLWTDEA---LRKLNN--LFKI ------------------------------------------------------------ ---------------------------------------------MARTSR---YKVKHR RRREGKTNYYKRRELI-KSGKPRLVIRKTNYRIIAQIVTATPIGDITHVWASSDQLR-AF GW----KGGLKNTPAAYLTGILVGLKAWMK-GIREAVVDIGLHSPVKGARVFAVLKGAVD VGLEIPH--SEEVFPS------EDRIKGEHIAKYAKMLKESNEELFKLRFSQYLK--NGL DPEELPKHFEEVYNRL------------LRRFEGMF------------------------ ---KKYNIPLPPIL---------------------------------------------- -----------------------------------TGEKEEA------------------ ---VEAEAE------MAKKGAAR--QVGVPW-------KFHIPPAIFINSLVPVADNSGA KLVRIIGVCGCKAKTVHRRIPGAAVGDMVVVSVREGKPEMRKQ---IMRAIVIRQRKPYR RQDGTWIMFEDNAVVITDEM--GNPKGTEIHGPVAMEAAL-RWPSIANLATMIV---MSY VPVYELPSRPRPGEEIVLPTGQKVRIRHVG---IPWIAP-PKKV-----------C---- -L----DDECPW------------------HGHLKVRGIVLEVKVVKVHPKFVVT-LHEW LKYDHKYKRYEWRRKKIHARLPPCID--VKPGDIVYIGETRPLAKTISFVVLGT------ ----------KN--------------------------------DVVPVKPIVKRLGETE DLRI-------------------------------------------------------- ------------------MSSKGGG----------------------------------- ---------SEGKTGWPTPPVIPQ------------------------------------ ------------EEWKNFRYRGYTFE--------------------ELLKLPMEEFIKLL PARQRRSLMRGL------KPEHRKLLEKIRKAKKLM-AEGKKV--V-IKTH-CRDMI--- ------ILPEM----------------------------VGLTIHVYNG--------ITY I-----------PVFISPWHIGHY----------------------------LGE----- ----------FALTC-KIVQHGE------------------------------------- -------------PGLKA-TR-------------------------------STLHVAAK ------------------------------------------------------------ ----------------------------------------------------------M- ------------PRKARIRIWGTDHKKVEELAREIVDIAKKCGVNVSGPIPLPTRRLIVT VRRAPSGQGY-------HTFDHWELRIHKRLIDM-DADERALKQLMRIRVPEDVKIEIEL I----------------------------------------------------------- --------MIN-----WVKSHHPRKQRKAYFN-APLHKRQKF-VTAPLSKELQKQY---- ---------------------GIK-RLPVRKGDTVLIVRG--DFK--GIKGKVVKVDLER VRIFVEGATIKKPNGE-VVYYP----------IHPSKVVIVELDLS-------------- ---------DPK-RKEL---------IERKRKMREEFL------------KKLQEAKQ-- -----KAREVIVIGG--------------------------------------------- --------EEKKQS---------------------------------------------- --------------------------------MP-LRPGRCYRYF--------------- -SGPPYTR---------LEYIHGA-PYVQIPKFDMGATSAAARARFDT-VVKLVAEEIG- -QIRMNALEAARQMAFKYL-NKVLGQE-NFYLRINVYPFHVLRENKMLA-MAGADRLQEG MRLAFGSPVGRAVRVERVGQVIMFVEV---E-ERNVEHAKEALRRAKSKI--SIPCRI-- ---------------------V-----VEKKQTNGKQ----------------------- ------------------------------------------------------------ -----------------------------M-VLL-DVLANAMVMIKNAEARGHKQVTIWP ISKLVGNVLRVMQRYGYIGEIEYIDDGR-GGKFIVHL----------------------L GKINDCGVIKPRFPVKYRDITKWEE--------------------KYLPSRDIGILIIST SKGVMSHIEAKQNKIGGVLLAYVY------------------------------------ MKVPYV------------REEVEIPEGVDVQVESDGRL--VVKVK--GPLGEIVKDFGSV P------ILVRK-EDNK-LVLETYFAR-------KFERALIGTIAARIRNMIKGVTKG-W RYKLKIVYSHFPIMVKVQ---GDK--LI-IENLLGRKDKIILQIP--KGVKVQVTKD--- ----DIIVEGIDRDVVSQFAANIEEATTLRG----DERPCPHGREGGPGVLDGIYVYAVE HVKA-------------------------------------------------------- ------------------M--------GLKINRPRRGSMAFYPRKRASDIVARFRTW-V- D-PKIG---KPILLGFAAYKAGMAHVVMIDDRQTSPFY--GKEIVRPVTILDAPPLRILG VRFYTFDPVKVA-EL---SIGEVWA-DLPDD-----V-----MKKV-------------K RKIPTLP---DKI------DVDKM-----------------------WKKVEDK------ ---LD--IVTEVRAICCTQP-----WLSGIGKKTPEIFEIPIGGVDDLN--QIIDYARNI LGK-EINVWDVFQPGQYIDVTAVTKGKGFQGPVKRFGIVIRPRWHKHRKGCRK--GGSV- GPQA-PGP-M-FTIPRAGQCGFHKRTEFNKRILKIGQ---KGE--EVTPKGGFKHYGIIP GPYIIVDGTVPGPVKRLVMMRFPVR---PRP-PTWP-TTPP-EIVWVSTQPLPTV----- ------------------------------------------------------------ ----MPRWHWSVTDEDI--IEMA-----------------------FRKFGVRVNPEQVV K----------------------------------------------------------- -----------AAGREYR-ISWKKAIETARFI--KYMTIKQAEWYLEQVIKLKMPIPIRT FKK-KQAHHT-----TPWE-GWPV-AKWPVKVAKAFLEVLKNLENNAIYKGL-NVDRVVI VHAATHKGRKIWNYMP-------RAFGR--STPWVQDT-VHIELAG-------VELPAEN ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------VPKR------- --------IRLVP-----IK--------------------------------------?? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????????????----------M PVIDLSSIDLKTLHWNDID----WRKFIWVKDH----------------------PMRAI YIEKVVVNIGVGTSGEKLEKAAKVLEEL-TGQ-TPSLRKAR--K--SIKEWGVRRGEPIG VMVTLRRN-KA-IWFLLKTLAVLDFTLRESQFDNMGNVSYGIREHILIPGVKYDPNLGIW GMDIAVRLARP-GYRVMYRKRCRSKVGKNHRVTKQEAIEYFKEILGVKV-V--------- --- >GCA_016699555 -----MV-VRKR--GMRKK-QRGER--THGHGDTKNWR-GSGNRGGVGK-AGSHKHKFSK YYPT------------------------------------F--GV------KV-RLNPK- --AK-----GKA-----L-NLEQIMQ----ELPKWKA-QGKV-VQ---------EEGQWV ID--GTRLK--IAKVL----GSGSIASNL-LFKN---IAVTEKAREKI------------ ----------------------------EAADGEVESE-FERVT--------GEEGNAEP QAE-------------------------------------------------------MI E--------------------KGFTKQAVNKVRL----------------YQYMKKEL-D RAGFTELDIV------KTPLVTRIVIHVSKPGLAIGKGGQNIRTLTETINREYGIENPQI EIK-EITTPELDSKSV----------IDRMKSAIER--GFAWRSVAFKTLEDVYRAGAQG VEIILSGK-LA----------GKG-------------GRKKQVRFS-------------- ----KGYMKKVGDQT-KLVDQAKVTSYPKVGAIG-------------------------- ----------LTVRII---------------RPGV----------FFPDKM--------- -------------NVK--------EYIAKK------------KARDAG-V---------- ------------------------------------------------------------ --------VE---A-----------QPVATET---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------KEP--------------------------------------- ------EAAA-------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------MVHVFSAQGQKVK DMALPSVFQT-PYHPALIKRAVLAVQSTRLQPHGKKPGSGRNNTAEYVGVRG-K-PTMYR TINVGHARLPR-MRN-RRGVLQGKVASVPQAVGGPSAHPSR-----VEKKLVENINVKER KLAIASAIAASVDAKIVKARGHHFD--AA-H-FPLVVDSSFEKIAKTKDVMKAF---ESL KVSADAEHAKER-KRIRAGKHKNRGNPYKQKKSLLIV-T-N-HASP-------------- -----IMKAARNIPGIDVIPVQRLNAEHLAPGTHAGRLTIWTEEA---IKVLATRGEQ-- ------------------------------------------------------------ ---------------------------------------------MSKTST---FTTKFR RRQEGKTNYVKRAAQL-KSGKIRAIVRKSTNHMRVQFVEHRAGMDYVLAEGSSIEL-KKY KY----TGHTGNLPAAYLAGYLAGKRLHAL-GKNDVIADIGVQKPPLQTRVFAAIKGIQD AGIQIAA--DAEAFPK------EERLHGKHIEAN----------------------PNKK DGAAFTKMVADTKQHI---------NAGVNK----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKSI-SANVTKGLTKKSRCVCADNSGA KEVEIISVFR--HTSRKRMQPRAGIADMVNVVVKTGKPEIRKK---VERAVIVRVRKEFK RPDGTRIKFEDNAVVLVDEK--GLPKASEVKGIIAKEVGE-RFPKIAGIAPGLV---MPK ----------------------------------------GKTT----------TT---- -K----EH----------------------PSEFPVRGNEFVGKVVSAKAPKTITVEREI TVYVPKFERYKKIRSKVHAHNPDYMH--AKEGDIVRIGETRKISKTKAFIVTEI------ ----------VG-HSKI--------EAKREEMKEGMRV----------KAHKAEAKAEEE AQ---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------MAKDFTFRGKTLP--------------------ELQQMPLQDFAKLC KARIRRSLERSAV-----NEDFKKFHARVQKGHELL-KAGKLPVNKPIKTT-LREFP--- ------ILPQM----------------------------VGLKIAVHKG--------NAF E-----------SFDVQPEMLGHR----------------------------VGE----- ----------YILTR-KTVKHGK------------------------------------- -------------AGIGA-SK-------------------------------SSTAITAR ------------------------------------------------------------ ------------------------------------------------------------ ------------MEKARITLTSPNYVSLNEISGKIIDLVDKAGIKHTGAIPLPTKKLLVS TRKGPCGGGT-------ETYERWQMRVHKRVIDF-EDDGRTLRRVMRVEVPENVQMAIGL KGKK-------------------------------------------------------- ----------------MTQTKNPGTQRLRVYE-ADQQARYSM-MSAHLSKELRTAH---- ---------------------KTR-NLAVRVGDTVKVMRG--DWK--GKSGEVTQVNYVR NRIFVKGITHKRATGK-EAFIG----------FRPSNVMITALEGK-------------- ---------EKR-RTVKG--------------------------------KAATKKAT-- -----------------------------------------------------------T KTAAPAKAAGKKE----------------------------------------------- --------------------------------MG-LRPAHCYR----------------G IDKPAYTRLAVTKH--DKNFIGTS-PHLKIRQFNMGNP----APEYTH-IIDLVNSSNMH HQLRDNAIEATRQNINRYL-GHKLGKE-GYFMRIRVYPYHILRENKQAQ-GAGADRVSQG MSHPFGRPIGRAARVRP-NQIIMSLLV---N-ESNLKVAKHALLRAAPKF--GFDIALN- VHNDTASLGTRPSKQIEEKVEVK----AVAAAEGAAAT----AEAGKEGAPAAAAGK--- D-AKAPAGKDAKGAA---AAKPAAGKADAKKK---------------------------- -----------------------------M-TQT-DPIADALVHIKNSQTASKTSITLRP GSKLLGQILRVMKEKGYIAKFTEKNDMR-GAFYEVEL----------------------N GKINQVAAIKPRYAVGKNEFEKFEK--------------------RFLPARDIGMMIVST SQGVMTHQESKEKSIGGRLLAYIY----------------------------------MA AKKPEK------------KHIVAIPAGVNVTYQ-H----GTMTAT--KGNKTSHKHLA-T P-E----VHIKI-EGSE-VHFAPI----NTK---RKTIAILNALMAHTQNLITGAEKG-Y FYKLTVVHSHFPMNIAKK---ENR--VE-ISNFLGEKAPRIAMILG-KDTQVEIKGK--- ----EITVKGFNKEDVAQTAGNMEIVTREKK---KDQRV----------FQDGIYIVEHG VNA--------------------------------------------------------- ---------------------------MTRRHAPRRGSISHRPRVRARRETPSFSSF-P- Q--VKG---PAKPLNFFGYKVAMVHLVAKSMHEKGRMQ--KLEMQIPTTVIECPPMHVYG VRAYAKD--PYG-LH---AMGEVTIDKLDKH-----A-----LERN-------------- ---QNFK---KK-------SDHKKNTKNTRTVST----------PTTLEDFVTK------ ---KA--ELHSIRLLVHTQP-----EKTNFGKKKAEMTELALSGTL-D---EQLNYAKEK FGK-MITIHDVFKDGSLIDVKGVTRGFGFGGVVARAGVKTFRP--KA-KYIRT--VGSI- SPLR-PGTVQ-FTVARPGQLGYHNRTEFNKKILKVLNA-QDAA--KINPKSGFEHYGVVQ NDYILVAGSVPGPIKRLIGLREPVR-AEESGHYKIG------PVTYVSTTGGAL------ ------------------------------------------------------------ ----MSKTTFNYQ--------------------------------------GTYDDTRMA R----------------------------------------------------------- -----------AITTNRP-ASVKYSLEIARCI--KGKTIQDAQTFLQNIVEEKAFLPLRT YHK-KIPHRK-----GASVFGTKS-GRYPWKTCEAWQALLNSVKANADVKGL-DTKKLRV VHANATHGFSRIRYQN-------Q--GRISNKAKKSKS-AHLEVIV-------REVKA-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRLMIQR-------------RGKGGTPWTA-SFHGK- ADVAY--MEYSATQRDGLMTGQ----VLELVDDPTKTSVLAEIVLDNNYH-IFNVAAEGL SVGQRIEIGK-------------QAA---LQIGNIMPVKDIPEGAPIFNVEIQPGDGGKL VRSSGGYALVMSK-EA--K-RVLIKLPSTKMISVHPDSRATIGNVSCGTRVDKPMMKAGN RSHERSAKKKLYPIVRGVAMNPNSHPFG-GSQH-HP---G-K----SKSTARSAPAGRKV GAIASKRTG-------RKKKN--------------------------------------- ----MNQNAE----------------------S----------------------PMKHI RIEKVTVNMGVGKTGEEHKRAMEIMQKI-TGT-KPVQTMCK--V--KIPAWGIREGLAIG CKVTLRKT-KA-EAFLKNALQAKEKTLNKKSFDKSGNVGFGIKEYIDLPGSKYDPKLGIR GFDVLVTLERP-GYRIKKRRTNPSPVGKAHQITQDEAVQFMQEKFGVKV-I--------- --- >GCA_018396815 ---------MGK--KKSRK-MRGSR--TCGWGVSGQHR-KSGMRGGFGK-AGRLNHKWTY MIK-----YARE--------------------------E-I--G-------KK-GFKSLR REKR------KYT----I-NVNELEE----LLKTKFS------DL---------NS---- IN--LAQMG--FKKLL----GEGVITKPV-KVIV---EKCSKSAKKKIEEAGG--EVV-- LLSEVKGV--------------------EALHG--------------------------- ---------------------------------------------------------MSI N--------------------KYFVKENLKKAEV----------------NEFLAREL-G KAGYVGTELT------KTPLGTRVVIYVARPGVVIGRRGQSIRDLTKILEERFGIENPQI SVA-TVENPELNPHVI----------ASQIVAALQK--GIHFRRAVYWALQRIMDAGALG AEIIIGGK-L------------TT-------------ERARHEKYS-------------- ----AGYLPKCGDPILKQLKTAVTYVQLKPGLYG-------------------------- ----------VKVRIL---------------PPDA----------KFPDK---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------PVIKPKQQEES--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------M-----------LTTQILKTKVYDLEGKEKG EIDLPQVFLT-PVRLDLIKKAVIAIQSHRFQPKGRDLMAGKRTTAESLGVGY-------- ----GLSRLPR-VKG-ENYPKARVAAFAPNTVGGRLAFPPT-----PEKKIKKKINKKEK LLALKSAIAATAIKELVAKRGHKFD--LT-KTLPLVVSDEIQNVTKTSDIVQIL---KKL GVWNDVEKVALT-VKIRAGKGKKRGRRKKMRIGPLIV-I-M-NDNG-------------- -----VKKAARNIPGVTVVELKNLNPEHLAPGTHPGRLTIWVESA---IKALSE------ GKFK-------------------------------------------------------- ---------------------------------------------MAKGPT---YRLSFR RRREGKTNYKKRRALI-LSKLPRFIVRLSNKYVLIQIAEAKPSGDYILVSAHSMEL-KKL GW----KGSCENTSAAYLTGLLAGFKALQK-NIKEAILDIGLRKATKGARVFAAMKGALD AGLKIPH--SEEILPD------ESRIKGEHVAVYAKSLS---QEEYNKRFSGYLK--NGL PPENLPNHFEEIKNKI------------IESIKTL------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---TAQQA--------MPGPKTRAV-SAKG---IVEY-RPRISRGLVAGARLVCADNTGA KILKLISVGG--YKSRLRRLPAACVGDMVRVTVVKGTPELKGQ---VFPAIIIRQRKPYR RRDGTWLQFEDNAAVLMTAE--GEFKGSEIKGPVAKEAAE-RWPRIANVANIII---M-- ------------------------VTKNIG---IN-VSL-PQKT-----------C---- -N----DPKCPF------------------HGNLKVRGKIIVGVVASDKMRNSIVVKRDY LHYVKKYMRYEKRRSKILAHKPPCIE--VKQGDIVKIAECRPISKNISFVVIEK------ ----------IE---------------------------------------------KR- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MPREFTYRGYTLA--------------------QLQQMSMDEFIKLL PARQRRSLLRGL------TEQQKILLTKIRKAKNSQ-SKENSK--P-IKTH-CRDMI--- ------ILPEM----------------------------VGLTILVHNG--------KEF V-----------PVEIKPEMIGHY----------------------------LGE----- ----------FAITN-KRVVHGA------------------------------------- -------------PGIGA-SR-------------------------------SSMYVPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------VSKARIKLSSTDPQGLNAICAEIKEIAEKTGVKFKGPIPLPTKRLIVP TRKSPCGEGS-------HTWDKWEMRLHKRLMDV-DPNERFLKRLMRIKTPENVFIEIEL M----------------------------------------------------------- -MKT--------------ISSKPSVQRKILYN-APMHVRRKL-LSARLSKELREKY---- ---------------------GAK-TLPVRKGDVVKIMRG--DYA--GVEGKVSEVDTKK IRIYVENVTREKTSGS-TVKVP----------IHPSKVMIIGLNLD-------------- ---------DKW-RV-----------------------------------ESLEKKKS-- -----LKGES-------------------------------------------------- ------------------------------------------------------------ ------------------------------------MRGKNYRRP--------------- -VGQPYAR---------AEYIHGA-PPPKISKFVMGDT----KGNFEY-KVSLKVKNDV- -QIRHNALEAARVAVNKSL-IKDLGES-GYMIKVKVYPHIVLRENKMIA-TAGADRLQEG MRRAFGKPIGRAARVKA-DEAVIEVYV---N-ESAIQYAKKALKAASSKI--PVPCKI-- ---------------------E-----VEKIEVVKSV----------------------- ------------------------------------------------------------ -----------------------------M-TLN-DPLANALATIYNNEERRKRECVIWP ASKLIGRTLRVMQKNGYIGEFEYIDDGR-AGKFKVQL----------------------L GRINKCGAIKPRFSVKKDEIEEWEK--------------------RYLPAENIGILILST PKGVISNKEAKELKTGGKLLAYVY------------------------------------ --MEEI---------EVEERVISIPENVSIAVKDN-----LVEVS--GPLGKLSEDFS-H T-P----VKIEL-RNNKEIAVY---AY-WPK---TKEIAIVGTVASLIKNLIKGVTKG-F TYKLKVVYSHFPVTIKVNE-KEKK--VV-IENFIGEKSPRIARIV--GNVKVEVKGD--- ----DIIVQGLNLKEVSQTASNIQQATKIKK---KDPRV----------FLDGIYIYEKK EGLEYGKP---------------------------------------------------- ------------------MG-------RRKWSAPRRGSLAFTPRARASSWIGKVGYW-P- K-IEG----TPTPLAFAGYKAGMTHVIAIDNVKGSLTY--GKEVTIPVTIIETPPMLVAG IRVYEKT--SKG-LK---TLSEAWMEKPPKD-----F-----ERLF-------------- ----PLP---EKF------NTEKQ-----------------------LEKIFSC------ ---ID--KIAEVRILLATQP-----RLVKKGRKKPELLEVKLDGGSIK---DQLEWAKKN LGR-EIKASEIFKEGQWVDVIAVTKGKGFQGPVKRFGVALLHH--KSRKTVRG--VGSI- GPWH-PHYVM-RTVPRAGQMGFHQRTEYNKQILKIGK---DGK--EVTPKGGFLRYGLIN TEYIMLKGSIPGSSKRLIVLRYGVR-----A-KNLP-IEPP-KIEYIDLESKQGD----- ------------------------------------------------------------ ----MPKWSYSIQ---------------------------------------NLDPDKTV K----------------------------------------------------------- -----------CSGRELR-ISPKTATEVCRAI--KGMKLNEAKAFLEEVKELKRAVPFRR YKK-EVPHRR-----MNE--KWYA-GRYPVKVADKLLKLLNELEANAEYKGL-NTENLII IHAASQRGRKLKRYIP-------RAFGR--ATPKFETL-THIELVG-------YEASS-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRILVQR-------------RGRGGSVFRAQTHKRV- SEATFP-SLK-EEETKSFVKGI----VVDLVHDPGRGAPLAYLRFEDGEE-CYIPAPEGL SVNQEISRGV-------------EAE---VKIGNILPLGRIPEGTLVCNVELLPGDGGKL VRASGAYATVVSH-TP--L-GTELKLPSGKTIYLNDACRAMIGVVAGAGRMEKPFLKAGA KAALMASRGRKYPRVRGQAMIAASHPFG-GGRHRHP---G-K----PTTVSRHAPPGRKV GLIAARRTG-------RGKKAGREAAESKQQ----------------------------- ----MSSANEV--SI---------------QEN----------------------PMRKI RIEKVSVNVCVGKSGEPLENAIKILSNL-TGQ-KPCVRKAK--R--TIKDFGIRKGEPIA CMVTLRKD-AA-ASFLKKALEAVGNKLKKSSFDNYGNFSFGIKEHIDIPGTKYDPKLGMI GMDVCVSLERP-GFRVKRRTIKESNIGKKHLISREEAIKFVKSTFGVEI-IED------- --- >GCA_012962495 -----MP-------KKRVKKIRGSG--SCGGGSRKNRR-GRGNRGGSGN-AGHLKHNYIR TIK--------------------------MGQE-------I--G-------KH-GFSRP- ----------KV-------------------------------VK---------EEYRYT FK--LKR----TLRSL---REDGKIDREL-------------------------YRFL-- VTKKELNIG-----------------DTP------------------------------- ---------------------------------------------------------MAV E--------------------RKFVEERIKKLRV----------------KEWMIQEV-R NAGFGGVDIT------RTPLGTQVTLFVERPGLVIGKGGRRIRMLTEKLKE-FGIENPQV SVD-EIEKPEFNAQLM----------ASLLARALER--GWYFRKAGYRFLYRIMEAGAKG CEIEISGK-L------------TS-------------ERARTEKFV-------------- ----DGTMVHTGDPAFNLVNKGFDVAVKKLGVLG-------------------------- ----------VAVRII---------------PSDV----------LLPDEF--------- -------------KVK-ED-----E-K-------------VEE----------------- ------------------------------------------------------------ -----------ESG-----------ELVDTQ----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------EVTEGQTSEET----G----------------------------- ----GEGNENEG------------------------------------------------ --------------------------------DKGN------EQRGN------------- --------D--------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------QKNWYEKINKKEM KKALRSAIAATAIKDVVNGRNHIFN--G---DLPKIVVDDIQSLSRTKEVIDFM---KSI GVYSDVERAKMR-KRTRAGKGKMRGRRYKKKKSVLLV-V-G-EDNG-------------- -----IVKASKNLPGVDAVNVRNLNVELLAPGAHPGRLTVWTKSA---ISYLEKWL---- ------------------------------------------------------------ ---------------------------------------------MATGPR---YRVRLR RRREGKTNYRKRLKLL-LSRKPRLVIRITNRRVITQIIEYDDGGDRVIITADSKML-EKY GW----KGDMNNTPAAYLTGLIAGKKAAEK-GIKEAVLDIGLISPVKGSRVFAVLKGAVD GGLDVPH--NPEVFPD------DSRIRGEHIAGYYSLSPD--------KFSDYER--RGL KPSKLPEHFDEIKASI-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------SG-------------------------MKAV-KAKISRSLPKGARLFCTDNTGA RELEIIAVKG--YRGVKRRYPEARVGDIVIVSVKKGTPDMRKQ---IQYAVVVRQRKEIR RHDGTRVKFEDNAAVITDEK--GNPKGSEIRGVVAKEAAE-RFGKIGSIASSII------ -------------------------MRDIG---ID-VKP-PEKE-----------C---- -N----DEECPF------------------HGTLPVRGQLFKGKVVKT-YKKSAVVEREI LRKVPKYERYLKKKSKIHAHNPRCID--ARVGDTVTIAECRPLSKTKSYVVVER------ ----------IDY--------------------------------------------EGS KG---------------------------------------------------------- ------------------MALKSKV----------------------------------- ------------------------------------------------------------ ------------VRPRDFKLRGYPLE--------------------EIQKMSLEEFARLL PSRERRKIRRGF------TEQEEKVLKKLRKNKI-------------VKTH-CRDMV--- ------ILPEM----------------------------VGKVIQIYNG--------REF V-----------RVEVKPEMIGHR----------------------------FGE----- ----------FAMTR-TFIKHSG------------------------------------- -------------PGVGA-TR-------------------------------SSKYVPLK ------------------------------------------------------------ -----------------------------------------------------MP--VK- ------------GYKARIRLSGLSPKDLDRICTQIKEIANKTGVEIRGPVPLPTRRFVVP VRKSPDGEGT-------ETWDHWEMRVHKRLIDI-AADERALRQIMRIQVPKDVNIEIVL ES---------------------------------------------------------- -MIP--------------KSVSPKKQRRWLYKTSKLHERHRL-LRATLSGDLRKKY---- ---------------------EKR-NIRIRKGDKVKIMRG--DFA--GHEGKVTEVDMKK LVIKVDGANVKKTDGT-EVSVP----------IHPSNVMIVDLGKV-------------- ---------DDV-RK-----------------------------------KILER----- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MA-KKPAKMFRRL--------------- -S-RPFTR---------KDYVDGV-PGIRIRQFEMGNK----KGVFPV-KLTLVAKEGV- -QVRDTALEAARIAANKFI-SRRVGSS-NFFLKVRVYPHQILREHKMAV-GAGADRISQG MRKAFGRPSGNAARVYP-GTKIISLWV---R-PEAFEFAMDALRRAGQKL--PTPVKI-- ---------------------E-----IEEGVELLKGKV--------------------- ------------------------------------------------------------ -------------------------------MLT-DNLSNAMSAIKNAERSGYHTCEVK- ASKLIGNVLRVFKDYGYIKGFEYIDDRR-GATYRIEL----------------------S GRINDCGAIRPRFSVKKAEFEKFEK--------------------RYLPARDFGIIVVST VVGVMSQKEALERGLSGVLLAYVY------------------------------------ ----ML------------EWVTDVPEDVEIQIQGDTVLGYTVSAK--GPKGENSKKLK-- ----FRGMHIEM-KDNK-VRVY---AE-EN----RKLKAMVRTFASHINNLIKGVSEG-F EYRLKIVYSHFPIKVRVE---GKE--VV-IENFLGEKHPRRAKIA--GRANVQIKGN--- ----EIIVSGIDKEECGQTAANLELITKVKN---LDPRV----------FQDGIYLIKR- ------------------------------------------------------------ ----------------------------MKEHRPRRGSMGFSPRKRAASIVPIFRSW-P- E-YNG----NPKLLDFSGYKAGMTHVVMIDDRKNSISY--GEEVVVPVTVIEAPPIKVAA VRVYRKT--PYG-FS---IAGEVWNNNLDDK-----L-----GKRV-------------- ----RIP---KKS------GDVDK-----------------------LKRIED------- --------IAEVRVIVYTQPY----RITGVPKKVPDLMEVKV-GGEVN---SALEYAISK LGK-EVNVAEVFKEGAIVDVASITKGKGFQGVVKRWGVISLNE--KYARSSKGRRVGCL- GPWN-PHHIR-PTVPQAGQMGFHHRTEFNKRIIKIGE---NGE--EITPSGGFVNYGVVR NDYILISGSVPGHIKRLVRIRDAIR---S-T-KVS--YDGI-NLLYVSTPSKQGR----- ------------------------------------------------------------ ----MARVDYAYK---------------------------------------AEDETRIA K----------------------------------------------------------- -----------AMGYEMP-ISFKHAVEICNTI--RGKKIEEAIEYLRDVVEMKKVVPFRN HKK-KVAHKR------ID--GWYA-GRYPQKAAKHILKVLQNLDANAEYKGL-DRDELVI VHAQAKKGRVLKRYMP-------RAYGR--ATPRFRVL-TTVEFI--------AEAVR-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------YILATEGM GVGDIIESGG-------------NAS---IKPGNTNFLRNIPEGTPVCNIESQPGDGGKF ARSSGTFGLVIAH-EE--K-RTLVQMPSGEMKWFNPMCRATIGVVAGGGRTDKPFVKAGK KFYKMRSKATKYPRVRGVAMCAVYHPFG-GGKHQHT---G-K----PKTVSRNAPPGRKV GSISARRTG-------GR------------------------------------------ ----MAA-----------------------ENN----------------------PMREI VIDKVVVNLCVGESGERHKKAMTVIEQL-TGQ-KPAITCAE--K--TIKNFGIRRGEAIG GKVTLRGS-KA-MEFLKKAFVVKENKLKRRQVGS-GEFSFGIAEHIDLPGVTYDPDIGMF GMDVCASLRRR-GYRVKRRKNARSKIGKNHRITKNETVEFLR-TLGVEV-E--------- --- >GCA_016207165 -----MA-RRIR--SRKFR-HRGNR--THGGGNTKNRR-GKGNKGGVGR-AGYHKHRRLY FIK-------------------------------------FE-GSTKRDKGLH-GFTNPA KKVY------AT-----I-SLDQLQD----AI-------GKFPQN---------DQGVYQ VV--IPQ-----TKVL----SGGQLSAKA-HVKA---YGFSAKAKEKIEKAGG--TTA-- TS---------------------------------------------------------- ---------------------------------------------------------MAI E--------------------KKFIQQALADLQI----------------KTLLNKEL-D KAGVSEILIQ------KTPIATRITVRVRRPGLVVGKKGKAIKELCELLERRFAIENPQF EVI-EVAQPSLDARLM----------AEKIGRRLEM--RPNAKPIMRMALREIMDAGALG AELQAAGK-IV----------GKG-------------GKAKTLRMR-------------- ----AGYLKKSGEPT-KWVRKGHFVAYLKAGAVG-------------------------- ----------ISVKIV---------------PPDA----------VFPDSI--------- ------------------------K-IPAT---------IPEKVP----VQPVEETVAA- ------------------------------------------------------------ --------EANAVDAL---------EAKPDAE---------------------------- ---------------------------EKPKK-----------------------TRKAP KPKK---Q----------------KALEP-----------------AEA-----AVPV-- ----------PP--ASDSQSPVSEEK---------------------------------- ---IGE------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MKAQLRTLKGDVSG EVALPEQFLE-PYRPDLIRRAYHAYRTQFLQPKGTYPLAGLQTTAEYFGRRH-A---WRQ TINTGRSRLPREKLS--GGRLGNV-RIVPHSNKGRRAHPPK-----PWKVIQERINRKEN NKAIRSALHASLEKTLVAQR-HRFDG-----TLPIVVSQDFAQVKRVSDAVDVL---TAL GLSSDLDRAKDG-RKMRSGRARLRKGGYRTPKSVLIV-Y-A-KDQG-------------- -----IHKAARNLPGVDVVSVKELNAELLAPGGQAGRLIVWTQDA---LDELQQAKLFE- ------------------------------------------------------------ ---------------------------------------------MTKATGPL-FQVHFR RRREGRTDYQKRLALL-KSGKPRLVVRKTNRYVIVQLVTFSPQGDRVIASATSKDL-NAF NF----TGKC-NTPSAYLTGLLVGTRAKAK-GVKDFVLDIGLHAPTQGSLVFAGLKGAVD AGLTAPH--SNERFPD------EARMNGEHIQ---------------------------- ----LKEAVLSAKQKI------------LGGAT--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MLGL-SAKITKGIITGTRLWCDDNSGA KIVQVIGVKG--FRARLRRYPRAGVGDIVFVSVKKGKPDIIKK---KEKAVIIRQRREFR RGTQ-RVKFEDNACILIDDA--GLPKGTEIKGCVAREIAD-RFPKVVGIASSVV------ -----------------------MSEKQKQ----------P------------------- ---------------------------------LRIRGAIVEGVVVSTRPKKTAIIQIAY TKSVPKYERLEKRKSRIAVHVPDGMN--VQVGQRVQAGETRKISKTKSFLLIKV------ ----------LP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MVRVTTYHGKNLE--------------------QLQALSLEEFVELL PSKPKRTMKRM-------GMQAKRFLKSFR--KKSKKK-------APIKTH-FRDMV--- ------VLPEM----------------------------VGHRFQVYNG--------KQY V-----------DVSVELAMLGHR----------------------------LGE----- ----------FSNPV-QMVKHSG------------------------------------- -------------PGIGA-TR-------------------------------GSKAVELK ------------------------------------------------------------ ------------------------------------------------------------ ------------MTKARIKLESKDVKELDEVCVSIKDISSKAGLPMKGPVPLPTKRLRIS TRKTPCGDGT-------DTYEKWELRVHKRLIEV-DANDRVLREIMRIKIPSSVNVEMTL G----------------------------------------------------------- ------------------MSSQPRKQRKALYT-ASLHQRQAM-VHAHLSRDLRAQK---- ---------------------KKR-ALPVRKGDTVKVVRG--KFR--GRSGKVTHVNLKK TFISVEGMVLKKQSGK-EVLAK----------IHPSNLVITAL----------------- ----------------------------------------------------SERKGE-- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MG-LRPARTCREV--------------- -KGQPWARISKKKP--RKSYVKGA-PNVKVRQFNMGS-----DQYFDL-EIDLVPDKPI- -QLRDNSLEAARQAINKVM-EKALIDQ--FFLQVLKYPHLVLREHTNLG-VAGADRISKG MKLAFGRPKGRMARIGA-GEAVFRARVL----KAALPVAKTAFKRGQLKLSGAFTLIIKD ISNEQWNIDKKARGVVSFRKKV-----VEEAKVEAAPAA-EGAAGEAAKPLEGKEGEKAD AKPAAP------------AKGDAKPKAEKK------------------------------ ---------------------------------M-DLLANALNQIKIAERKGLRTVRIEP TNKLVRDVLNVLKSAGYIADAEFSDDAR-GGRFVVTL----------------------N GAINECGVIKPRFPVGKKTWEKFEQ--------------------RFLPSKDIGVLIVTT PQGVVTHNAAKEKLVGGRLLAYAF------------------------------------ ---------------------MKLPDGVNVSVDQG-----TISVK--GPKGQLSRVFD-- ----PQRIIVDV-QGTD-VTVS---PN-AKK-ATRELKSLAGTFQSHIANMAQGVVHG-F EVKLQLVYSHFPVSLEVK---GQT--VA-IKNFLGEKNPRHAKVV--GSTQVDVKSQ--- ----SITVSGIDKEAVGQTAANLISATGVGH---RDERV----------FQDGIYYA--- ------------------------------------------------------------ ---------------------------MGKK-GPNRGSRAYWHRKRAPGLVPRIRTW-S- Q-------HGKGLQGFAGYKAGMAHVVMTEYR-DSPSK--GQDVAKPVTLLVTPPLFIYA VVAYKMT--PYG-WK---VVGEVPAVNAPKQ-----V-----ARTR-------------- ----PVA---K--------KTQKK-----------------------LDDYK-------- -------DADAFRVIAVTLP-----HKVGL-KKTPEVMEIA-LGGSKD---EAFQYAASV LGK-EVPVKDVFNAGELLDAISVTKGHGWQGVVKRFGVALNPH--KATQARRH--GGAL- GGET-QAKVM-YTIPRAGQTGFHRRTDRNKRIVAVADT-AQSY--Q--PKGGFRHFGLAQ GACLVLEGSIPGPAKRLVRLRKTFR---AHN------PVEL-TVKQVVA----------- ------------------------------------------------------------ ----MGLYKYSLK---------------------------------------P--AAAVG K----------------------------------------------------------- -----------AQGHDWD-ASYKDLTQVCRAI--RGLPVKKAFHVMQDAINQTRAIQYVR FAK-GAGHRS-----N----LGGKQGRYPKKECRLMTKLLRNAVNNAVQNGL-DESSLVV KHASANKQNVFRRYRQFWVSGTVLGYGK--HATWANYVTARAEIVLRGK---TASEEKTE ----------------------------------------KPKKAKTKKATEKQSE---- ------------------PRASPEKNV-----QDAEEKTG-------------------- --------------------------------SKPEKSAKP--------QTQKPPSKIET PAFQ----ENVAE-----EKK--------------------------------------- ---------------------MGTRLIPQR-------------RGKGGPTFRTPKHRFF- GAAQY------LAPTPETLNGE----VIGLLSSPAHSAVMADVLLENGGR-MAYLAPEGL RKGALVSVGP-------------QAK---IQVGNVLPIGQIPEGVYVFNVELMPGDGGRM TRASGSSALVVGH-DEDTG-QTVVRLSSKRLKTLSPECRATIGVSSAGGRKEKPFQKAGN HFYAMKARNKYWPIVRGTAKSAYDHPHG-GRSF------G-K----SSSVARNTPPGRKV GHIASRRTG-------RRRGRIRVQQDE-------------------------------- --------------------------------------------------------MKHV HLEKVTVNIGVGQGGQALENARELLTRL-TQR-KPANTLSR--T--RNPTFGLRKGEAIG AKVTLRGK-PA-AEFIKKALTAREQTIKATSFDSTGNVSFGVPEYIDFPGMKYDPAIGII GFDVCVTLSKP-GLRVKHRKIASRKLPRKQRVTRDEAIAFMKDQFSVNF-A--------- --- >Bin78_genes -----MT-FNKR--KKKTR-QRGSS--GHGWGHKKKHR-GAGNRGGRGM-AGTGKKGDAK K---------PRIWAN---------------KK-----Y-F--G-------KY-GFKKK- NIKK--II--KT-----V-NVDYFEK----KIDKLLS-KNLI-EK---------QGDLYI ID--IEKLG--FNKVL----GSGKLTKKC-KISA---PFFSKKAIDKIKSAGG--EVI-- Q---------------------------TKVKDEIKKENKPETQ---------EKKKEVK QSK-------------------------------------------------------MI E--------------------REFIKQKKIEFQI----------------QEFISNSL-R NSGHSHTRLQ------KTPLGEKIIISASRPGLIVGREGKNIKKLTIDLKKRFKLENPQI EIE-EVKDINLNSRIV----------AERIASELERFGLSRFKGIGHKVLGEVMGDKALG IEIIMSGK-I------------PS-------------SRAKRWRFY-------------- ----QGYLKKCGDIAITGVDTAYTTAHLKTGAIG-------------------------- ----------IQVRIM---------------PPGT----------KLPDKV--------- ------------------------E-L------------L-EEKEEI--V---------- ------------------------------------------------------------ ---------VEEVK-----------EEPVEEK---------------------------- ---------------------------NNTKK---------------------EEKPKLS SK---------------------------------------------------------- ------------NKKDLEKPSVPQ------------------------------------ -----KEEKKTEK----------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MELTILSKTKTSIG KIKLPKQFEE-VLRPDIIKKAFLTLRSRKIQPYGADPRAGLRASADLSRRRK-K---YRG SYGHGISRVPRKILSRRGTRFNWVGAVAPGTVGGRKAHAPN-----AEKKWELKINKKEK KKAIRSALSATMIKELVEERGHIVP--E---NYPFIIEKSIQNFDKTKQVKDFL---IKI GLEKELERVNK--KTIRAGKGKTRGRKYKKTRGILLV-V-S-DDCK-------------- -----IERAARNIPGLEIAKIKEINVEILAPGANPGRLTLFTQDS---IEKLGKENLFI- ------------------------------------------------------------ ---------------------------------------------MKRKTS----NLQKR RKREGKTNYKKRIRLL-LSNKPRLVIRPSLNNISAQIVEYHQKGDKIIASANSKEL-DKI GW----KFSKGNLPAAYLTGVLAGINAKEK-GIKEAILDIGLSTPTKGSRIFACLKGVID SGVNVPA--SKEIFPS------EDRIKGEHIAKH-------------ASSIK-TK--ENI DLTQIPKTFEEIKNKI------------IKVK---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MRSI-KAKITRGLPVGAHVHTCDNSGA KIIKIFGVKG--HKTVKGRLPAAGVGDLVVASVTSGRPDMRKQ---VVFAVVVRQKKEYR RPDGIRIKFEDNSAVVLKDDK-GNPKGTIFKGPIAKEACE-RWPGIAKIASIIV------ ------------------------MDKN------E-NKA-SEDN-----------C---- -K----DKNCPF------------------HGNLTPRGKNFTGVIIAKDTHKTATIEWNY RLFIPKYERSETRRTRIRVHNPSCIN--AGIGDVVNVVQTRPLSKTKNFVITEN------ ----------LG-KEKRF---GKKIEAKEESKEIIGKKE--------RKKEEPENSKEKI IEE---------------------EPKEENK----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MVKKEFKYKGKTVE--------------------ELKKLSLAEFIDLI PARQKRSLKRGL------SDQQKILLNKIKSGKT------------NIKTH-CRNMI--- ------ILPEM----------------------------IGATVSIYDG--------KSF I-----------KIVILEDMISHC----------------------------LGE----- ----------FTYNR-KRVAHSA------------------------------------- -------------PGIGA-TK-------------------------------SSSALSVK ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------INQVCDYIKSISEKTGVDVRGPIPLPTKKLKIS TRKGPDGGGT-------STWDRYEMRVFKRVIDM-QIDERALRLVMKVPIPEGLNIEIEM IDN--------------------------------------------------------- MTKT--KFSET-----WKRSKQPRKQRKYRFN-APLHTKNKF-LSSHLSKELKEKY---- ---------------------NRR-NITTRKEDKVKVLRG--QFK--GKIGKIERVDLKK TKVYITGMELIKKDGT-KVLYP----------IHPSNILITELNLD-------------- ---------DKR-RI-----------------------------------KTLARK---- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MAKIRKFCAYRKI--------------- -E-RPYTRISKFR---KKSFIRVT-PNSVITKFDMGSK----TKQFGY-RLDLISKQPL- -QIRNNALESARMTCNRLV-ETELGKN-GYRFKIRPYPFHILRENPLAA-GAGADRMSTG MKMSFGKPIGTAVQLKK-SQILFSISV---N-KQNIDLAKRALKKASYKL--PGGYSI-- ---------------------V-----ANELPKQK------------------------- ------------------------------------------------------------ -------------------------------------LANALSKIMNSEKIGKESCLIKP ISKTIKSVLTIMNENDHIGEFKEIDDGK-GGLIKVNL----------------------L GKINKCGVIKPRYPIKRDGFEKFEK--------------------RYLPAKDFGIIFIST TKGIMKHEDAKKKNIGGILLAYCY------------------------------------ -MKYMI------------KEEIEIPKDIEIKIENG-----LVDIK--GPKGSIQRKLI-N P-K----LNLKI-EENK-VLLS---SE-KVS---KREKTRAGTIKAHLKNMIHGVSEG-F VYKLKICSSHFPMTVSSN---NNQ--LS-VKNFLGESIPRNINIK--EGVDIKIEED--- ----IIIIESPDKELAGQTAASVEQLCRLTN---KDKRI----------FQDGIYMIEKA GKAIK------------------------------------------------------- ---------------------------MPHMNKPRSGTLQFSPRKRAKRVFARVRSW-M- E-TK-----EAKLNCFAGYKVGMSHIIVTDNKSTSPTK--GEDISIPVTIVECPPIKTAS ILFYKKT--PYG-LK---VSAALMAEKLDKE-----L-----KRRI-------------- ----CIP---K--------KIKNK-----------------------IEDFK-------- ---PE--DYDDIRVLVYTQP-----KLTTIGKKKPELFELAIGGKT-E---EKFNWAKEN LGK-EINIKDVFVEGQQVDAHAITKGKGFQGPTKRFGTSLRSH--KSEKGVRG--PANL- GCW--VGNRS-WTVAHAGQMGYHQRTEYNKWLIKIGD---KPE--ELNRKSGFRSYGIIK NQAILLKGSIPGPSKRVIIMTPTRR---A-N-KLTP-KEAP-SIQYISQ----------- ------------------------------------------------------------ ----MSKRNNSTK---------------------------------------VANKEHTA T----------------------------------------------------------- -----------AVGRTLQ-ISTKQSIEVCNSI--RKMPLEKAKTLLKEVMALKKPIPFKR YT--SMGHRK-----G----KLAA-GRYPLKTSKEILSLLESAEANAQYKGL-STANLII KSIIANKAGNQWRY------------GR--QRRRRMKR-TNIDIIL-------EERA--- -----------------------------------------ITKSESKPKQKVD------ ----------------------------------TETKV--------------------- -----------------------------------NTQTKK--------PEPT-PIKPQE ------------------EKQK-------------------------------------- ---------------------MGKLLIQQR-------------RGKGSPTYRSPSFRFK- GKIKL-----NKLGKE-TINGK----IIDIIHCQGHTSPLIQIRYDNGEE-ILTSAPEGV RVGETVVAGS-------------NIP---IKSGNILPLKDIPEGTTIYNIENIPGDGGKL VRTSGSSAKIVSK-LS--N-KIIVKLPSNRQKEFKPECRACIGVIAGSGRTDKPILKAGK KYFMKKAKNKLWPKVSGVSMNAVDHPFG-GSSSHTK---G-R----PLQSGKNDPPGRKV GNIAPKK---------RKK----------------------------------------- -------------------------------MN----------------------PMRAI RIEKITLNIGAGKEQTKLEKGIKLLKNI-TGI-NPIKTTTS--K--RIPGWGLRPGLPIG CKLTLRKE-KA-KEILARLLEAKNNQLDPNQFDMNGNVSFGIPEYIDIPGVKYDPEIGVS GLEVCVTLERP-GFRIKRRKIKKRKISLRHSIKKEEAIEFMGKNFKIRV--GEAE----- --- >GCA_007116295 ------M-THKR--KKNSR-TRGSK--THGGGAMKKRR-GAGNRGGRGN-AGSGKRGDAK K---------PKFWKN---------------KK-----Y-F--G-------KF-GFSSI- -NKK--EV--NT-----I-NLTHLSD----VLDSLTK-KEKA-VK---------SKDMYK VD--LKDIK--VHKLL----GSGSLNKKV-EITA---QQASKKAIEKVEKAGG--KVI-- L---------------------------PNQD---------------------------- ----------------------------------------------------------MI E--------------------RKFVSQNIREYQI----------------KSFLFNEL-T RAGLADVKLQ------RTPLGDKVVVIASRPGLVVGKGGSNIKRLTKELEKKFGLETPQI EIE-EIKDYRTNAAIT----------AEMIANSLERFGTQRFKGVGHKTLQSVMDAGALG IEITISGR-V------------PS-------------SRAKTWRFY-------------- ----QGYLKKCGDISISGVDKAHQIAVLKTGVVG-------------------------- ----------ISVTIM---------------PGDT----------KLPDKI--------- ------------------------E-L------------L-DEPQTV--VE--EIEEKA- ----------------------------SEKKEVKKAPAKKKEEKATPKK---------- ---------EKEVA-----------EEKP--K---------------------------- ---------------------------AKKKE---------------------ETKKEEE ------P----------------------------------------------------- ------------KKKKVAKKTSTK------------------------------------ -----KKEEKASEK---KEVKKA------------------------------------- --------------------------------PTKK------KATKK------------- KKSEDK----------------------------------------MKLKILDQKAQEKG TLKLPSQFAE-AVRVDLIRRAVKAIFANNRQAYGAKPEAGKRHSAFLSKRRR-K---YRG TYGIGQSRTPRKVLNRSGTRFHYVGAVAPQTVGGRRAHPPK-----ASKIWTQKINKKEN RKAIRSALSSTINLELVKGRGHIPP--P---SYPFVLTDDFTQISKTADLIKAL---ETL GFNQELSRAQS--FKVRAGKGKNRGRKYKAKTSILFV-V-N-DYCD-------------- -----LVQAVNNIPGCDIISVKDLNAYILAPGAQPGRLTLFTQSA---VKELEEKGYFNS DYKG-------EKQ---------------------------------------------- -----------------------------------------------MRAK---YTVKHR RKREGRTNYKKRLGLL-KSKQTRLVIRKSNTKIIFQFIEYSPDGDKVLFTYNSSAL-KDQ GW----NHSYKSLPAAYLSGLVVGQKALDK-KIKTAILDIGLQSPKKGGRIYSALKGVID AGVKIPS--DESIFPD------EERLSGKHI----------------------------- QDESVNKDFEKLKQKI------------MK------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKPI-NAKMTRGLPVGSRVDTCDNSGA KVVKIFSVKG--HKTVKGQLPSAGIGDLVKVSVIKGRPDMRKT---VNWAVVVRQKKSFR RADGTRVKFEDNAVVVLKDEK-GNPKGTILKGPVAKEACQ-RWPGIAKIANIIV------ ------------------------MEKN-------------------------------- ---------------------------------ISRRGRTFTGKVIRAKMAKTVTVEWEK SKYIPKYERYEKRKSRVKAHNPESIN--AKEGDIVVIQETRPLSKTKHFIVTQI------ ----------VE---------------------------------------------EK- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKIFTYKGKTLE--------------------ELQAMSHEEVAQLL PSRQRRKMLRGF------SEEEVKLLQKLNKKGT-------------AKTH-LRDMI--- ------VLPEM----------------------------VSKTVKVHKG--------NSF E-----------SVIIQPEMIGCY----------------------------LGE----- ----------LALTR-KKLKHGG------------------------------------- -------------AGVGA-TR-------------------------------SSAHQSVR ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARVKIASTDIGKVNATCEYIQGIAEKTGVVIRGPIPLPTKKLKVT TRKSPCGDGT-------ATWDRYEMRVHKRLIDL-GIDERALRLIMRVPIPEGLNIEIEM MDN--------------------------------------------------------- -MKS--KFSKT-----WIASVQPRKQRKYRAN-APLHLKSKF-LSVNLNKELRQKY---- ---------------------GTR-NIRVRKGDTVRVIRG--DHK--TLEGKVADINLKK ALVYVDGIEHSKREGA-KKRIP----------LQPSNLQIVDLDMS-------------- ---------DSK-R-K--------QKL-----------------------DLNKK----- ------------------------------------------------------------ ------------------------------------------------------------ ----------------???????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????----------------- -----------------------------M-TLN-DPLSNVLSHIDHYERLGHKLVHAKN NSKLIREVLNIMQEEGYIGGYEQKE----DRTLNINL----------------------L GNLNKCGVIKPRFRISLKDFEKYEK--------------------RYLPAKDFGILIIST SKGLMTHIEAKQKRLGGTLISYAY------------------------------------ -MSSGL------------EVIIELGEGVKAQLENR-----ELTVT--GPKGEIKRKII-E P-A----INFNI-TSEH-IKIS---TK-KDS---KSQKKALNTLTAHLNNLVKGVKEE-Y VYKLKICSGHFPMNVSVK---GDV--FE-IKNFIGEKVPRTLKIM--SGAQVNIQGE--- ----IIEVKSINKEVAGQVAASIEKLTRRPN---FDKRI----------FQDGIYIIEKD GRVL-------------------------------------------------------- ---------------------------MAKKGKPRSGSMGVWPRKKAARKIARVRSY-P- E-VK-----EPKLMGFAGYKAGMTHLMVVEQNKNKPNA--GQETFTPATIIECPPLKIFA IRLYKDQ--N--------VSKQLNFKS-DKE-----L-----SRAL-------------- ----HVP---K--------K-FST-----------------------KEDLDKVD----- ---LE--KYDDLRVLVYTQP-----KLTSI-KKTPELFELPIGGNI-Q---DKLNFVKEN LQK-EINITDVFEEGQLIDTHAVTKGKGFQGPIRRFGISMTAS--KSEKARRN--PGSL- GGWKSQGHVM-YRVPHAGQTGYHLRTQNNNLILKIGK---DPK--EVNPKGGFLRFGNVK STYVIVKGSIQGPKKRLITLTPALR---P-K-KKIP-HSSD-SITHISTESKQ------- ------------------------------------------------------------ -----MKTRYSFQ---------------------------------------D--KENMA K----------------------------------------------------------- -----------AYGKSLP-ISTKVAVEVSNFL--RGKTTQKAKAILERVLQKKQAIPYKR AVD-GVGHKP----------NMAS-GRYPQKASEEYLSLIKQAEANAEAKGL-GE-ELVI VHLSAHKASRPPRQ------------GR--QTRRKFKR-THVEIVV-------EE----- ------------------------------------------------------------ --------------QEKTKK---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRLIQQR-------------RGKGTTRFRAPSFRYK- GEIKI-----LNKE-----YYV----VKDLIRSAGHSAPLIEAEYNDKST-SLLIAPEGV SVGDKYLIG--------------QGE---PSPGNILPLSKIPEGTNVFCIEATPGSGGQF VRGSGTSAKVVSR-SE--K-EVKLLLPSKKQKSFHPGCMAMIGIVAGGGRVEKPILKAGK MHHITKSRNQYYPVVSGSAMNAVAHPFG-NKRTSRK---S-N----AKPAPKNAPPGRKV GAIRPRRTG-------RKNK---------------------------------------- -----------------------------MKNT----------------------KMKEI RIEKVTLNVGAGKDQKVLEKGVKLLKNI-TGI-EPVKTITY--K--RIQGWGLRPGLPIG CKITLRGK-EA-HKMVERIVYAKDDVFKESFFDDNGNISIGISEYVDLKDAKYDVDIGMM GLQANITLMRP-GKRVSTRKSRPGKIGKSHKITKEEAINFMKENFKVKI--GDQQ----- --- >Bin350_genes -----MV-VRKR--KKKDK-QRGMR--THGKGNTKNVR-GAGSRGGRGR-AGSHKHKFTM YYDD------------------------------------F--GG------QK-AMKAR- --PK-----NRA-----L-NLCELEL----ELEKLVA-KKKV-EV---------QGDTYI LD--GRKAK--ISKIL----GRGNIEKKL-VLKH---ISVSKKALIKIEAAGG--KLE-- SVK-----------------AAPGEAKTENPGKEVEN----------------------- ----------------------------------------------------------MI E--------------------RYFIEQGMKKIRL----------------ETYFKKEL-N RAGFTGMKIN------KTPLVTRVTLRVAKPGLAIGKKGSTIKNLTADLESKFGIDNPQI EIQ-QIEKPELDATAM----------VDKIVALLSR--GYSWRSVAFRSIEDIMNAGAQG VELVFKGK-LA----------GKG-------------GRKRKERIA-------------- ----KGYMKKAGGQA-SMVDYCQGDAYPKAGAIG-------------------------- ----------VKLRII---------------KPDT----------VFPDKI--------- -------------KIE--------DIIEARKNA---------KKEDEE-TDE-KET---- ----------------------------KEE----------------------------- --------VKEDKS-----------EEKEEKK-EVK------------------------ --------------------DTKE----EKKEEKT------------EEKKEKPKAEKEV KKKTPVK---------------------------------------KEK----------- -------KEEKVKEEKK-EKPKEK-TEK-------------------------------- ----KEEKPKEKEEKV-------------------------------------------- --------------------------------EKKK------EEKSE------------- KGKE-EAGEKEEK--------------------------MPQRHSDVSVPVYSVEGKKLK DEKLPAVFST-EFEPELIKRAVLAMQTAAKQPQGTKKLAGRDNTAQYRGCRD-L-PTAER GINVGHARLPR-LNN-RSSRLSGRVASIPRAVGGPKAHPPK-----VEKKHIEKINKKER KKAFKSALACTTDFELVSAR-HRIE--KV--QLPFIVEDKFEGISKTQEIVKVL---GLL GLGTDLNNAKDK-TKRRSGKGRKRGRVKKVKKSLLIV-T-G-KKSA-------------- -----AYKAARNLPGVEISCVKDLNSELFAPGGQPGRLTVFTESA---IAELK------- ------------------------------------------------------------ ---------------------------------------------MKTT-----RTMQFR RRKENKTNYAKRLAML-KSGKNRVLFRKSNKRITMQLISYEETSDKTLASTYSDKL-KQF GF----EGKC-NLPSAYLTGYWLGKLALAA-GTTEAIFDAGIHMGVLGGRAAAALKGVID SGLKVPA--EAKAFPR------EDRLEGKHIET--------------------------- ------KGFQEAKSKIDSLN-----AGKVKE----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAI-SASQTKCITQKTRLFCTDNSGA KEVEMISAIG--HKSRRRMNPKAGIADMMNVVVKKGKPEIRKK---VERAVVVRVKKEYM RPDGTRIKFEDNAAVIVDEK--GVPKGSEIKGVVAKEAAE-RWPKIAGLAQQVI---MTE -------------------------------------------------------C---- -E----DKKCPI------------------HGGLKVRGQTFKGKVISSKPTHTVTVERTM IIFVPKYERSKKARSRVHAHNPPCIN--AKEGDIVLLGETRKISKTKSFAVLKV------ ----------LS-EEK-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKREFTYKGKTVS--------------------ELLPLSQEDFAQLL PTRAKRSLLRGV---------NKRLNQRMDEAD----KLGKKD--KEIRTH-NRSAV--- ------ITPRM----------------------------VGRLFGVYSG--------NQF Q-----------KVEIMPEMLGHK----------------------------LGE----- ----------LALTR-KRLRHGK------------------------------------- -------------AGIGA-TK-------------------------------SSTAITAR ------------------------------------------------------------ ----------------------------------------------------------M- ------------VQKARIKLTSSNYEDLNEISDRIVDVAKRTGVKFAGPIPMPTKKLVVP TRKSPNGGGT-------ETYERWQLRIHKRIIDI-EADERTLRRVMRVEIPQQVHVEIEL IEK--------------------------------------------------------- -MAKDCGFSATG---DIMDSKKPKKQRKAFHE-KPLHLKSKD-LSANLSKTLRKEI---- ---------------------GKR-SFTIRKGDDVKVMRG--DYK--GKTGKIASVNYSR QRILIEKLTRKKSDGT-EVMVP----------FKTSNLQIESLDKS-------------- ---------DEK-RF-----------------------------------KRQKKKTE-- ------------------------------------------------------------ --------KEAK------------------------------------------------ --------------------------------MG-LRPGHCYRELTD------------- ---RAFTRIAITNH--KKNFVGAA-PGLRIKQFNMGNS----AKEYSH-IVDLKSENAL- -QIRDNAIESARIAVNRYL-TKYIGKE-NYFMRIRIYPFHCLRENKQAQ-GAGADRVSQG MAHSFGKVIGRAARVKK-GQILISVLV---N-EEHVEIAKQALERAKIKL--PCKISIK- IHTDVKSIGTRPR-------TIK----MREGEKKEEAE--DKAEAETK-GEKAEEDK--- G-EEAEKGEKTEEDK---DGKKEEDGKEDKAEE--------------------------- -----------------------------M-SLM-DPISNALISMKNCEMVAKKECEFKP GSKLLGNILRVMKENKYISDYSFSDDGK-SGFYTIKL----------------------G GKINECRSVRPRYTVKKDEFEKFEK--------------------RFLPSKDIGILIVST AQGVLSHKQAIEKKIGGRLLAYVY------------------------------------ -----M------------KETIEFNEPLKVSVE-A----QTVTLT--AGDKTETKTFR-C K-D----VDFLV-EGNA-LILEGH----NDK---KKTSSIINTVKKHVLNLAFGLENG-Y EYHMKVVFSHFPMNIQLA---GKE--LV-INNFAGGKKPRKANVVG-ANTTVEVKGK--- ----DIIITGSNKEHVGQTAANFEKATVIKK---KDLRI----------FQDGIYLVTKG VKQESA------------------------------------------------------ ---------------------------MAKKHKPRSGSLAYYPKKRARSEKPRVKSF-K- R--KGD---EAKAMNFFGYKAGMTHVLGTDQHQKSATF--GQKVRFAVTLLECPPIKVVG YRAYTKS--SKA-LK---AISEEWTTELPKE-----I-----SRRL-------------- ---AGLG---KK-------KKDKKAKKEGEGKAEEKTEEKKSSKKKGAEAIAEK------ ---AE--KISEVRLIGCLQP-----WLTGIGKKKPEIVEISIDGPV-E---KQLGYAKGL LGK-ELSAADVFTAKDFLDVSSVTKGKGFQGVVKRAGVTIQGR--KA-KKRRI--VGSI- GPWH-PANVM-FTVARPGQLGYQHRTEQNKKLLKIG---SD----NVNPKAGFKKYGLIK NDYLMIEGSIPGPAKRCIALRSGLR-KQPLERHMIE------EVDFVASKTL-------- ------------------------------------------------------------ ----MVKKNYQEE--------------------------------------AD--TKITA K----------------------------------------------------------- -----------AMMKNKD-VSLKYSTEICREI--RGKPVFKAEKFLNAILEHRTFLPLKR YNK-KVAHRK-----GQAVSGVKS-GRFPKKACEAWLELLGYAKANAENKGL-DSEKLLV RHCFASCGFRRQKMQP-------K--GHVAGKTRHSKS-SHIEIIV-------QEVASL- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGTRLVTQR-------------RGKGSPTFRA-KKKGK- KSA------YCKPEKE-IIKGE----VVDFSKEVGRNGLLVKVLTGN-SA-FNVVAAEGM FIGQEIQIGT-------------NAE---IGIGNVLPLSNIPEGCPIFNVEMRPGDGGKL VRATGSYALLSTR-SV--K-TAMIKLPSGKMKKMQADCRATIGNAACGERTDKPFVKAGA KFHYMKAKSRTWPNTRGVAMNAVDHPFG-GEQH-HA---G-K----SKSVSRHAPPGRKV GAIASSRTG-------RKKRK--------------------------------------- --------------------------------------------------------MREI RIGKIVANMGIGESREDMEKGVKILEQV-TGA-KVVKTKAR--V--KQPKWNIRPGLEIG VKTTLRGE-KA-IEFLKNTLYAKENTLLKRNFDDKGNFGFGVKEHIEMPKVKYDPKLGIM GFDVLVSLERP-GYRVKTRKKQKAKVGKKHVITKEEAIAFVTEKFEVSV-E--------- --- >Bin525_genes -----MI----R--QGKKR-QRGSR--THGWGSGKKHR-GAGNRGGKGN-AGSGKRGQQK K---------TKYLAHG-------------GES-----P-L--G-------KH-GFQ--- ITRQRPSL--KA-----I-NLYELES----NLATWLK-EKQI-KK---------EKDTYI IK--LKELG--YDKIL----STGTIKSKL-KITA---KAFSKTAEEKLKSAGG--EAI-- K---------------------------EA------------------------------ ----------------------------------------------------------MI E--------------------REFIKEKIRNFKI----------------QERISSTVNR YAGIDEIIVE------KTPLGERVIIFASRPGLVIGSGGETIKALTHDLRTKFGLETPQV EVK-EIRDPDGRASVV----------AKKIASDFERFGPKRYKATGYRALTNVIRAGARG AEIRITGVGI------------PG-------------ARARSWRFF-------------- ----AGYLKKSGDTAETVVDKAFEVATLKRGTIG-------------------------- ----------IKVAIM---------------PMGV----------ILPDDV--------- ------------------------T-I------------K---------VVEEKVSEK-- ------------------------------------------------------------ --------EVEELKEV---------TKIVEKKA--------------------------- ---------------------------EPVKK----------------TAAAPIEKKSTE ------------------------------------------------------------ ------------KPKKTPNKPTKK------------------------------------ ---VAKKVKKDEKK---------------------------------------------- ------------------------------------------GTKKS------------- K---------------------------------------------MKVDTYSITGVKKA QIELPIQFQE-SIRGDLIRRAVISQQSHNYQPYGSDPLAGTKQGQATPKRRK-G---YKT TYGHGVSRVKRKFSWRRGLRFGFVGAFVSSAIGGRKAFAPQ-----VNKVISEKINIKER RKSIRSAIAATANKALIEKRNHQIK--DI-KSIPLVIEDKLETLKKAKDVKIAL---TKL GLSKELARTSK--RKVRAGRGTTRGRKYKTKVGPLLV-V-S-KACD-------------- -----AVKAARNLLGVDIVEVNCLNAELLAPGTQPGRLTVWTKSA---IERLGKERLFK- ------------------------------------------------------------ ---------------------------------------------MATGPR---YVVKFR RRREGKTDYKKRLNLL-KSELPRFTVRISNKYIVCQFIKHETEGDKTLLTVSSKKL-ASY GW----KNSGKNLAAAYLSGYLAGKLAKKK-KVTKAVLDIGLQSPTK-SKLFAVLKGVVD SGIDIPH--SEKAFPS------EERISGAHI---SEKIQKD------------------- --------FKTTKEKI------------NK------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKPI-KSRITKAFPVGAIIPVVDNSGA RQIQVISVKG--YKTRTCMLQAAGIADLISGAVKAGKPDMRHK---VVQAVIVRQKQEFT RPDGTKVRFEDNGAVILKDVRLGLPKGSTVKGPIAKEVAL-RWKQVAKIASQVL---MA- ------------------------EKKKAE---MKKVAS-PKAKPVKKVVVKAPTC---- -S----DANCPM------------------HGKVRMHGRVFEGTVVSDKMQLTVTVQWPR QRYIPKYERYFKTRSKIKAHNSPCVA--AKLGDKVRIAECRPISKTVNFVVMEV------ ----------LN---------------------------------------------ETN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MVKEFKYRGKTLD--------------------ELKAMGLQELADLL PARLRRSLRRGL------TDTQKKLVEKVETNKRK------------LRTH-CRDMV--- ------IIPQL----------------------------VGHTILVHNG--------KDW L-----------AVNVTLEMLGHY----------------------------LGE----- ----------FAQTR-RLTKHSG------------------------------------- -------------PGVGA-TR-------------------------------GSRSKSVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKARIKLFSTDIKKVDDICNQIIEIAKRVKVKHAGPIFLPTKHMEIP VRKSPDGEGQ-------ASWDRWEMRIHKRMVDI-DADERALHQVMKVSIPQDVNIEIQV IE---------------------------------------------------------- -MKT---FSKA-----WIKSKKPGKQRKYRAN-APIHKKRKM-MSGHLSKDLRKEH---- ---------------------KKH-AFPIRTDDKVKILRG--EFK--GTIGKVERIDVKN MKIFVAGAERVKGEGQPASKYP----------IDPSNVKIITLELK-------------- ---------DKQ-RK-----------------------------------EALKR----- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MARLRDASAYRKV--------------- -K-KAYVRTSKYR---KHNFIRGV-PGSKVVMYDVGNK----KRDFPC-SVLTRAKKMV- -NLRHNAIEAGRIAATKHI-EKVIGKE-NFHLKIRVVPHHIMRENPLAT-GAGADRFQEG MRHAFGKPIGYSARVKK-GMPMFQIFV---E-EESLAHAKEALRKANSKF--PIACTY-- ---------------------E-----IIR------------------------------ ------------------------------------------------------------ --------------------------------MA-KLLVETLSAIKNAEGRSKKEIVRRP VSKLLLDVLKIAKREGYLGEITVYKDAR-GGEVKINL----------------------I GAINNIGVISPNFSVSYHNLEKFEK--------------------RFLPAKDFGRLILTT PKGVMTHIDAREKKVGGKLLAFVY----------------------------------MK LKAE-----------------VQLPEGVQAKKEDG-----DLVIS--VGDKSLRRVLP-R R-K----LNVKI-VGNK-IELS---VK---D---KKDRALVGTFKSHINNMYTGLKEP-F VYKLKACSTHFPMSVKLE---NDM--LT-IQNFVGRKAPIIVKIP--AGVDAKVEKD--- ----IVTVSSNDIELAGQAASRIEQATRLNK---KDRRI----------FMDGVFMTKKA KREI-------------------------------------------------------- ------------------MG-------HTKRKRPKRGAKQVWPRKRASREYPRIRTR--- --ASHS---EIKPLAFAGYKAGMTHIFVVDNRPKAPTK--GEEIRLPVTIIECPDLLVAG FRLYPTTF-------------DVLSDKLDET-----L-----GRRI-------------- ----NLPKKAKN----KIADAEKK-----------------------LDKTK-------- ----------EIRLLVYTQP-----KKTLIGKKKPELFEVGIGGSDVK---AKFDYAKGM LGK-PISVDAVFKDGMFMDTHSVTTGKGFQGVVKRFGVKLRSH--KSEKGQRR--IGTL- GPWT-PKKTP-WWVPMCGQMGYHTRTDYNKQLLKISEE------D-VTPNGGLLRYGTVK NKYMLVRGSISGPKKRLITFTHAIR-----KHP--A-EEAP-SVVSVSRRSQQ------- ------------------------------------------------------------ --MRKISYAGSME--------------------------------------------DAV Q----------------------------------------------------------- -----------VAGRNLP-ISRKLGREIAIFI--KGKMADRAIGELNRVAKGELAIPYVR FNK-DTPHRK-----G----DMMS-GRFPKKSSLEIIKLIESLKANAENKAL-DSDSIKI IHASCQHSAKAWHY------------GR--HRGRKRKL-AHFELVG-------VEAEEKE ----KRYGKKKEEKKPVAKPAP----------------KKVEVKKEAPKKEVKPTP---- -------------KKEVKKIASTP----------IEKKSV-------------------- ------------------------------------EQAKP--------TPKKVAKPKQE ------------------VKK--------------------------------------- ---------------------MGTKLIQQR-------------RGKGSPTYRAASHRYF- GEISYP------TIRPKAVKGE----VIDIVNSRGHSSPLACVEFEDGQL-ALVPAVQGL NVGAEVFTGS-------------NAK---PTLGSIVELKDIPAGVSISALEKTPGGDAEF VRASGSSAKIVNK-DE--G-KVIIQLPSKKRVILDERCRALIGKLSGAGRKDKPFVKAGK KALSMRAKGRLYPRTSGVAMNSCDHPFG-GTHTRTK---G-K----SKSVSRDAPPGRKV GHIASRRSG-------RLKR---------------------------------------- ----MVYLQLELQNQN-----------LQQMES----------------------KMRKI EIEKVVLNMGTSPEPNDVKKAMGLLEAI-SGV-KPVNTYSK--K--RLATWKIRPGLPIG AKVTIRGK-PA-MVLLKRLLYAVDSVLKKKQFTQNG-FSFGVKEYIEIKDAKYDPKLGML GMDVCVSLKRP-GFRVRSRHMQKSKIGGKHIVTKEDAIQYAETQLGVKF-E--------- --- >GCA_013306035 -----MMEMXTRH-RKIXK-LRGSR--SHGWGQVKGHR-S--HPGGRGN-AGLMKYKWSW TVK-----YDPD--------------------------H-FT---------KP-SLNPPN RKIV------KKW----I-NVGDLDGFF---------------LH---------SKSNTP ID--LEKLG--YEKLL----GSGSVQGSY-ELLV---TSFTKQAQSKIEKAGG--KIS-- ----------------------------PRS----------------------------- -------------------------MEK---------------------------SQTTM I--------------------KKVLAKNSDLTAL----------------NDFLKDQL-M DSGYSGVDIV------KTPVGTTLNLFVNKPGLVIGRRGSGIRSLTEALETKFNITNPQI SVT-EVKIPELNAAIM----------ASRLASSVQR--GQPMRRAANWTMRMIMNNGARG VEIQVAGK-M------------RS-------------DRASFEKFK-------------- ----AGVVPKAGFTALQSVDXASCESLLKVGLVG-------------------------- ----------IKVFIA---------------LPEK-----------YRPEF--------- ------------------------KHL-------------THKSAEAP-AEAPAEA---- ------------------------------------------------------------ ---------PAEAP-----------AEAP------------------------------- ----------------------AEAPAEAPAEAPA------------EAPA-EAPAEAP- -DEAP----------------------------------AEAPAEAPAE----------- ---------APAEAPAEAPAEAP------------------------------------- ----ADDSHNLSDIKD-------------------------------------------- ------------------------------------------------------------ ----------------------------------------------------------ME KIQVPLVFTT-PYNPRLIKRAVLAIQSHSRIPKGTDPLAGERSSSESWN----------- -TGRGISRIGR-IKS-HSGPRGGSAAGVAGVKGGRNPHPPR-----SXKNIYQKLNKKEN TSALMSAISASMNREFVINRGHRID--NL-LNLPLIIIDDIESVNRTKDIRLTL---INL GFSNELERLSD--VRLRSGKSRLRGRSRKIKKGPLIV-C-S-NDLG-------------- -----IGDACENLLGVDLVXAKNLNVLDLAPGTEAGRLVIWTKNS---FSNLSSNILKSV KLNAS------------------------------------------------------- ---------------------------------------------MTR----NTHVPMFK RKRTGQTDYSKRKSMI-VSRSVILSIRISNKHSTFQFIEPKIEGDSIKSSCHSSQI-TKL GW----KGSGKSLYGLYLTGYLAGKKAKSA-GLDKAILYIGRREFGSGLKIIYALKGVID AGIDITA--NNDIFPD------SEKF-------------KTDT----TQ----KI--IE- ----------EINSKYG------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------MPA-KAKIQVSS----------RRYITRALPVGATIVCADNSGA RTLKIIMVQG--WKGRLSRLPAATVGDQVTVVVEKGPPELQKQ---TFPAVIIRQKYAVR RPNGSRITFEDNAAVIITPE--GEMKGTDIKGPVASEAAE-RWPRVSNAANTIV------ -------------------------MKNIG---LN-IEQ-PTTD-----------C---- -D----DHHCPF------------------HGQISIRGKLIQAKLIKNKARRTAVVRIEF FHYVKKYMRYEKRRRNIIAHISPCLN--VNDNDSVTIGECRPLSKNVSFVVLGR------ ----------TN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MPKEFKYRGYSMK--------------------ELQSMSLDEFLKLV PSRQRRSLTRGL------SENKKKILEQIDNLNK----DSSDK--S-IRTH-SRDLI--- ------LLPKM----------------------------LGLTIHVYTG--------KEF V-----------PVEVQPSMIGHY----------------------------LGE----- ----------YAITN-KKVQHGT------------------------------------- -------------PGIGA-SK-------------------------------SSLYVPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------GQSARIKLTSSNLPNLQXVCKEIKDITDRTGIKARGPQPLPTKKLRIT TXXAPSGNGT-------STFDRWXLRIHRRLIDL-XADDRTMRQLMRLKVPEDVFIEVNL SNK--------------------------------------------------------- ------------------MVKRSKIM-KEYYN-APQHIVSKR-ISASLSDSLQSQY---- ---------------------NTK-TVRLRKNDVVKILSG--EYK--NLDGKITHVYLAE GRISVDGITREKLAGG-TTPIK----------IHASNVMVTSLDLK-------------- ---------DSK-RK-----------------------------------TKLER----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MHGGNYRVA--------------- -NGMPLS----------KKYAPGT-PNVRIARFQTGAR----NSDYEV-KIQLVXKEKC- -QIRDNALEAARVGANKKM-NKVVPET-NYQLSVRLYPHTIISENKMIA-AAGADRLQEG MRNAYGKPMGHAARVNI-GSIIYEIRT---Y-EKHIPEAKRALKTASSKL--PGYTSI-- ---------------------T-----VSPIDQ--------------------------- ------------------------------------------------------------ -----------------------------M-PAL-NTLANLFSNLQNAELRNKNECLVIP SSKVIVDTLNTMKKNNYIGEFEVIDDKL-GGKIRIQL----------------------L GKINKCGVVSPRFAVAKSDYSLWER--------------------RFLPAVGIGILVVST SKGIMTHTDAEKLNEGGRLLGYVY------------------------------------ ---MSI-------DRSSLTREIILPEGVNAQFTED-----LLTIT--GPLGSTSKDFK-L I-R----AKLNI-DSNK-ITVE---SL-GSR---KKQRATFGTTVAHVNNLIIGVTEG-Y TYKLKTAFAHFPLTVKAE---PGK--IV-VENFYGERGNRIAKII--GKSNVSVKGD--- ----EVIISGINIEEVSQTAANLEQSTRIKN---KDLRV----------YLDGIYLFEKG RGKE-------------------------------------------------------- ------------------MG--------RKHSAPRRGSLAFRPRGRHGTLNARIRNW-P- D-VKSX---EPTLLGFMGFKVGSMNVLTVDNVDKSPTF--GKPIFNHATVLSCAPMTIVG LRAYKNS--LDG-LL---VFSEVYAKQLPKE-----I-----SRKQ-------------K L---------NSD-------YDSK-----------------------VSKIKDN------ ---LE--SLNKLCAIVSVPP-----KQAGLSQIKPYXFEIGLGGITLE---DQFEYIKNN LGK-KITVSDIIKPGMLVDALGVTKGKGWQGPVKRFGIKKKQH--KSRKTVRE--VGTI- GAWS-PANVM-YTVPRAGQMGFHQRTEFNKKVLFIAN--EKEQ--SVNPDGGFTHFGLVP EDYXIIKGSLPGPIKRPVILRYPIR-----S-KGQK-LDVP-KVLKLSTQKGELE----- ------------------------------------------------------------ ----MPKFGYSFE---------------------------------------QYDPVVHA R----------------------------------------------------------- -----------ASGREIN-MSPKAAREVCNTI--KGKKLSAALSLLDDVILLNKSIPFRR HKK-EVGHRR-----STD--KFHA-GRYPVKVAKHISLILNEVESNADFKGL-DVSNLRI IHAATHRGRTIPGYIP-------RAMGR--SSPMNHEL-VHIEIIA-------G------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRILVQR-------------RGDGGMRYRSHNKGKI- APASY-----PFLDSNNTVTGI----VKDLLHERGRSVPLAKIVFND-KI-SYLPAVNGL RVNQEISIGS-------------SSE---IQDGNILPLRDIPEGTSICNIERTFGDGGKM AKSAGTSALLYSK-TA--DGGSIIRLRSGKSIVVXTNCRATIGAMSAAGFKEKPFLKAGN KARFAQAFGHLHPKVRGVAMGSHYHPFG-GGRHQSP---H-Q----STSTSRNAPPGRKV GSIAASKTGPGR---ARRRSRIAEX----------------------------------- -------------------------------MS---------------------SQINQV KLCKIVINIGVGKSGEPIEQAKRIISEI-CDQ-TPVTTYAK--K--SYREFGIQKNSPIG VKTTLRKQ-IA-EDTLKKLLTACGNKVSKRSFDLTGNFSFGVKEHIEIPGTKYDPRLGIW GMDVAVSLEKT-GYGVKRRQIRPGTVGKRQQVSPEDAITFAKENLGVIV-EE-------- --- >GCA_015063125 ------M-PSRT--KK----FRGYR--THGRGK-KSGR-GAGIIGGHGM-AGYGKTGKIG MLK-----EDRN--------------------------Y-F--G-------RH-GFKRPQ CTVE--AN--RT-----I-NVGELNE----KIETFVT-MGFA-KK---------EGDAYQ LD--LTEAG--IDKLL----GNGNIDIAV-NVTV---ESVSGKAREKIEAAGG--SIA-- E----------------------------------------------------------- ---------------------------------------------------------MAA E--------------------RKIVAEHVRRVLL----------------KEYLMKEV-S RAGFGGLDVQ------RTPMGTRVILTTERPGLVIGRRGQTIKNLTQVIEEQFGFDNPQI EVQ-EVQNASLNAQIM----------AEKLAFSLER--GWHFRRAGHSTVRRIMDSGARG CYIIVAGK-L------------SG-------------QRHRTEKFK-------------- ----EGNIKFCGETKAQFIEHGYAVAKLKMGVIG-------------------------- ----------VTVEIM---------------VKDA----------KMPADI--------- ------------------------T-V-------------LNK----------------- ------------------------------------------------------------ ----------TEAA-----------AVLPDL----------------------------- --------------------------FNAPAPV--------------------------- ------------------------------------------------------------ ------------EAPAEAEAPVAEEVE--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------MAATTNVYGLNGAVEG SVKIPEAFET-PYRPDIIKKAVLAAAANGRQPYGPAPRSGMRHAVSFRGK---------- --GTGSARNQR-IHG------LGKAGESPNNVSGRRAHPPV-----PERIWAQKVNKKEA KIARASALAATGCADCVKARGHQFD--DN-VSFPIVVDDKFNEMKETSAVIELF---EKI GIGYDLDRAKEG-RKIRAGRGTMRNRKYRTPVSVLIV-V-A-DDERNA------------ ----PIFKSAANIPGVTIEEVKTLSTSILAPGGDAGRLTVYTKAA---IEAIGGWTQ--- ------------------------------------------------------------ ---------------------------------------------MATGPR---YKVAFR RRRELRTDYYTRKKLL-TARETRAVVRRSSRNISIQFADFTMGGDNIIATATTKDLK-KM GW----EYSCSSIPAAYLVGYLAGKRAMKE-GVEYAVLDIGMQHVQHGGVLFATVAGMTD AGLEVPH--SEDVLPD------EDRLKG-------KHIDDAIE----------------- ------AAIDSMKQKM------------EAE----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKGI-AGNQTRGLQNGSQLDVIDNTGA KVIEIITVPG--YHGTARRVPSAGVGDLVIASVKKGTPAMRRQ---IVFAVIVRQRRPMR RPDGTMVFFEDNAAVITTET--GEVKGTDIKGPVAREAAE-RWPRVSATASTII---MT- -----------------------AKIKDIG---ID-VVP-PTSE-----------C---- -N----DPNCPF------------------HGTLGVRGQTIDGVVATVRMNKTVVVERNY LRYMHKYERYEKKSSRYVAHAAPCLG--LKVGDRVTIAECRPLSKTVTFAVIEK------ ----------KE------------------------------------------------ ------------------------------------------------------------ ------------------MAKKIIAG-SAKA----------------------------- ---------SRRKS---------------------------------------------- ---RKKASAIQARRKKEFLYRGFTME--------------------ELLAMPFEEVLGLM PSRSRRTYLRGL------NYEQQLLFDKLKDATE------------PVRTH-RRDLP--- ------IIPQF----------------------------VGKTVSVYNG--------QNF K-----------DVEIKPEMIGCF----------------------------IGE----- ----------FVQTR-KPPVHSG------------------------------------- -------------PGVGA-TR-------------------------------SSKFMPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------SQRARISLSGTDPAKVDSVCAQIKGISQRTGVDIRGPVPLPTKKLKVP CRKSPDGEGS-------ETWDRWEMRIHKRLIDL-DADERALRQLMRIQVPDGVNIEIVL RSA--------------------------------------------------------- -----------------MVSSKARVQRKAQAN-ATAHVKRKM-LSAHLSDELREKY---- ---------------------GKR-AARVCKGDTVIVVRGNEDIR--NIEGKVINVYTKT GRVAIEGITIKQADGT-EAERP----------IHASNLVITKLNTE-------------- ---------DAW-RM-----------------------------------DSLSKKEA-- ------KE---------------------------------------------------- ------------------------------------------------------------ --------------------------------MV-RKPASMYRQI--------------- KG-QAYTR---------REYMGGV-PASRVSQYEMGNT----RQEFPV-TLTLKVKNRV- -QVRHTSIEAGRIAANKVL-TSQAGVA-NYHMTVRAFPHVVLRENKLAT-GAGADRVSSG MRQGFGKAVGTAARLER-NQAILTVRV---N-PDKIAVAKDALWRASMKF--PSPCYV-- ---------------------D-----VEKGKEFVN------------------------ ------------------------------------------------------------ -------------------------------MQS-DPLNDAMCVIKNASVNGKAECTIEP SSKLIGRVLKVMQDYGYISQFEYVEDGK-AGKFHVML----------------------E GAINDCGVIKPRYSVKVTEVEKVEA--------------------RFLPAQDFGLLIMTT TAGVITQERAKELGIGGKLLAYVY------------------------------------ ---MTI-------AGKI-ESTIAIPGGVSVTYDAG-----TMKVK--GPKGELSRNFA-Y P-N----ITIAV-GEGE-VSVS---CE-YPR---VKDKAMVGTFVAHINNMVKGVTEG-F KYDLKIVFSHFPMKVAVK---GDR--VE-INNYMGGHAPRYANIV--RGCTVKISGQ--- ----DVTVEGIDIEACGQTAANLEKATQRGG---FDKRV----------FEDGIYIVGKS HKVRQ------------------------------------------------------- ---------------------------MPQRRRPQKGSRAFGPRKRAQSQTPRLDSW-P- E-VSG----APKIQGFAGYKAGMTHAFIVDKRAKSTTS--GMELQVPVTVVEVPPMKIAA VRFYESS--IVG-LK---TAGEVWAKDLDPL-----L-----DRRL-------------- ----NVP---KNH------E-EAT-----------------------FARYDGL------ -------DIEDVRVLAYTQPK----VVSGVPKKVPDLMELRIGGGTID---ERVAYAKQI LGT-EVGFTDFSPEGSLVDVIAVTKGKGFQGVTKRWGVKLLSH--RNSK--HRRGIGNL- GPKR-PGYVR-STVPGSGQMGYHQRTEFNKKVVKVGA---DGT--EVTPKGGFLNYGEVR NTYVLIHGSVPGPTKRLIRFRDATR---M-P-KKAD-TEAV-DVTYVSVESKQGA----- ------------------------------------------------------------ ----MVNSGYTAV----------------------------------------ADPDTTA K----------------------------------------------------------- -----------ALGREMP-VSPKFAREVAGMV--RGMKLETAQRALEEVIEKKRPVPLKR YNK-RVSHKA-----G-----VGP-GRYPVKAAKAILSVIDSAAANAEFKGL-DTSNLAI ATISVSRGQVIPGHMP-------RAHGR--ATEWNQDT-INVEVIL-------QEVE--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRLIPMR-------------RGRGTSLYRSPSHRHV- DDVRLP-A---------FNEGK--AVIKDLIQAPGRTCPLAVLDIDGKTD--YQLAVEGT KVGQTIMIG--------------GTQ---VAAGNILMLANIPEGTLVHNVEARPGDGGKF VKTAGSSGTVVSR----GD-KVNVLMPSGAIKEFSPNCRAAIGVVAGGGRGDKPLAKAGK NVLTLRSRSKAPFKTKGVAMNPVDHPHG-GGSHAHV--GG------PNCQKRTASPGQKV GFLPPKKKV-------RK------------------------------------------ -------------------------------MS----------------------TMRDL HVEKVVVNIGVGEAGERLAKAEKVLEMV-TKQ-KPVETLSK--T--VNRDLGIREGMPLG CKVTLRGD-SA-VDFVKQALAIREMRVPEYSFDQEGNMSFGISDYTDFEGMKYDPEIGIF GMDISVVLRRP-GNRITQRALLKRRIPKSHRVGRDEAIQYMKDNFQIEV-VQ-------- --- >GCA_011051215 ------M-PHKL--RKVRK-MRGSR--THGYGRVGQHR-DAGSKGYR-K-VGRHKHLWSY VVT-----YEPD--------------------------Y-F--G-------KK-GFTSPQ SIRR--KE--NV-----I-NLKDLEE----LAQKLSV-E-----K---------EKGKLH ID--LSSLG--YTKLL----GTGKISKAL-IVNV---ASCSKSAAEKIKQAGG--EVL-- T--ASQ----------------------E----DGE------------------------ ---------------------------------------------------------MSI V--------------------KRFISESIKRTEI----------------DEFLQKKL-E RAGYGGVDIS------KTPLGTHVVIYAMRPGLVIGRGGETIKELATTLEQHFKVSNPQI SVS-EIEVPELNAFVV----------ASRIASALER--GVHFRRAGFWAINQVMAAGALG IEIVISGK-L------------RT-------------ERAHFEKFR-------------- ----AGYFPRCGDPALKYMRKAEVHVQLKPGIFG-------------------------- ----------VKVKIM---------------PPDA----------KFPDKI--------- ------------------------E-I---------------IDALPP-EEVEEKI---- ------------------------------------------------------------ ----------EEPS---------------------------------------------- ----------------------L--------------------------------KEQV- -SEEP------------------------------------------------------- ---------LKESADEQVESASKE------------------------------------ ----VEESKEAKE----------------------------------------------- ------------------------------------------------------------ ------------------------------------------MPAKKTVKIFDLQGKPVD KLVLPDVFET-PIRPDVIKRAVLAVQSSRLQPQGRDPMAGKRTSAESRGTGM-------- ----GIARVPR-VKG-----GGGRAAFAPSTVGGRQPHPPK-----AEKKIVKRIPKKEA RLALFSAIAATASKEAVAARGHRIE--DV-PEIPLIVTDQIEELNRTSELEVAI---TNL GILADIYRVKES-RKIRAGKGKRRGRKLKQAVGPLIV-V-A-ENKG-------------- -----IAEAASNLPGVDVATISNLNVELLAPGTHPGRLTLWTSGA---IKQLAK--LYSG GKAE-------------------------------------------------------- ---------------------------------------------MARSSV---YRVPLR RRREGKTDYRARKALI-LSEKPRLVTRCSLKNVTVQIVIAKPHGDEVLASAHSREL-MQY GW----KAPTGNVPAAYLTGLLCGLKAKAK-GVTEAILDMGLAAPTKGARVFTALKGVLD AGIEVPC--SEEKIVA------E-RIEGKHIAAYGKSLAS-NPEVYAAKFSKYLE--QKI SPEKLPDHFTKTKANI------------VNSF---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----KKGEKKA---------------------MLSH-GQKITRGLLAGSILRCADNTGA RVLRLVQSIG--YKGRLRRYPTATVGDRVTVSVRQGSPDMRKK---IFQAVIIRQKKAYR RIDGVWIQFEDNAAVIITPD--GEMKGSEIRGPVAKEAAE-RWPRIASAASIIV------ ----------------------------MS---LT-FKK-PKKS-----------C---- -N----DRNCPF------------------HGTLAIRGRVLEGVVVSAKMDKTVVVERGY LQFSPKYVRYERRSGHIPSHNPPCID--AKEGEKVRIAECRPISKTVSFVVVER------ ----------LE---------------------------------------------EK- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MPKEFMYRGHTLS--------------------SLQAMSMDEFINLL PSRQRRSLQRGL------TPEQRILLGKIREAREAA-KKGENI--T-IKTH-VRDLV--- ------ILPEM----------------------------IGVKILVHNG--------KEF F-----------PVEIKPEMIGHY----------------------------LGE----- ----------FAITN-KPVKHGT------------------------------------- -------------PGIGA-SR-------------------------------SSMYVPLK ------------------------------------------------------------ ------------------------------------------------------------ ------------MRKARIRLTSTDYSKLEEVCEELKNIAQKTGAKINGPVPLPTKRLRVP VLKAPSGEGT-------ATWDHWEMRIHKRLIDI-DSEERVMRRIMRIRVPEEVHVTIEL I----------------------------------------------------------M QVTR--------------PVKSPRKQRKQLYT-APAHLRHKF-MSAPLSQELASSK---- ---------------------GVK-SLPVRKGDTVQVIRG--DHK--GFEGKVNRVDLKR QRIFIEGLTREKVDGT-TIFVP----------VHPSKVILKNLKLD-------------- ---------DKR-RQ-----------------------------------EIVERKKLA- ---LPKKEKEPKKVEKL--------PEKAAEVEK---------EKAVAEPEIAVAT---E KKPSKKVTEAKPKVARKESAEKKAKSGSTAEEKAPAKRKKKEAAATEEKPVKKETKPEKV KKAPAKRESGVKKGGT--------------------MHARNYRAV--------------- -KGQAYTR---------KEFAKGF-PPPKITKFTMGDT----NGTFDI-EARLVALKRA- -QIRHSALEAARVATNRLL--MEKLVN-DYLMLVHPYPHVILRENKMIF-GAHADRLQQG MRKSFGKAIGTAARVEP-GQTIITVRV---K-ANALETAKESLKRGSAKL--PIPCRI-- ---------------------E-----VEKLASSSAVDSV-----------KTETGAA-- ------------------------------------------------------------ -----------------------------M-KAM-DTLANGLITIINNEIRNKRECVISP ASKLLGRVLRIMQLNGYIGEFEFIDDGR-SGKFKVQL----------------------L GRINKCGAIRPRFPVKVGEFEQWEK--------------------KFLPSRDVGILVVST SSGVISHREAEEKNIGGRLLAFVY------------------------------------ MRLPEI------------SKTIQVPDNVEVTVEGR-----KVTVK--GAKGTLTRDFS-S T-P----ISIES-NGKI-VRVW---AK-WPR---KKEAAMVGTAHSHIQNMITGVEKG-F SYKLKIVFSHFPITVKVQ---DKT--VV-IENFTGERRPRKAKII--GDVKVKVQSE--- ----DIVVEGINLEDVSQTAANIEQATKVKR---KDPRV----------FLDGIYVYERS EGIE-------------------------------------------------------- ------------------MG-------HRKTHAPKHGSLAYLPRKRAKRPVARIRYW-P- K-VSVD---VPRLLGFAGYKAGMTFVFTIEDRKRSPSF--GKEVMRAATVIETPPMLICG IRTYTKT--PYG-LR---NLTEAWMKDPPAE-----L-----DRAL-------------- ----VLP---ENF------DTEQM-----------------------LQKLEQN------ ---LP--KTAVVRVIAATQP-----KEASLSKKKPEIIEIEIGGGTIP---KQLEYAKSL LGK-TVTAEEVFKDGQYIDVVAVTTGKGFQGPVKRWGVTILQH--KGRKTKRG--IATL- GPWN-PHHIM-YSIPRAGQMGYHQRTEYNKRVLKIGK---DGK--EVTVKGGYIRYGVLK GPYILIDGSIPGPEKRLIRLRYPAR---P-P-KEAP-ETAP-QITYISLDSPQGK----- ------------------------------------------------------------ ----MPKWGYSIIE-------------------------------------EELDPEKTA K----------------------------------------------------------- -----------ASGRELR-VSHKASREVCRTI--KGMMLANAKAYLKAVVAKKKAVPFKR YKK-KLGHRA-----GLT--KAFA-GRYPVKAAEQILRVIESAEANAENKGL-DVDRLRI LHAVAYPGVKIKRYMP-------RAHGR--ASPKYETT-THIEIVL-------EEKPAQG ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------GAL-------- ------------------------------------------------------------ ---------------------MGKRIRVQR-------------RGRGGMPFRAATHKRV- APAKYPVSISSKDYFESSINGV----IESFVHDAGRGAPLAFVRFENGET-CYIAAPEGV SEGQQISLGG-------------KAP---SEVGNILPLGKVPEGTLVCNLELRPGDGGKL AKSSGAYATVVAH-TP--Q-GTMIRLPSGRTRYVDDYCMATVGVVSGGGRTEKPFLKAGE KFHLMRARGRKYPRTRGRAMVAAVHPYG-SSK-RSA---R-K----VTTTSHGAPPGQKV GLIAARGAG-------QKRKRKTT------------------------------------ -------------MW---------------EEQ----------------------PMLKP RIEKVVVNISVGKSGEPLEKASAVLKEL-TNQ-TPAKRKVK--K--TIRDFGIRKGESTA CIVTLRKQ-AA-VDFLKKVLPVVDNKLSRSSFDKQGNFAFGIKEHIEIAGVKYDPNIGIF GMDVCVSVNRP-GQRVKIRRKKKAQIGRQHLLTPAESIAFVKQTLGVEI-V--------- --- >GCA_002685855 -----MP-TQGRTPKKNIR-QRGSK--THGWGAMKKHR-GAGNRGGRGN-AGSGKRGDAK K---------PCFW-----------------KL-----K-V--K-------PK-GFSSK- -SRS--IS--IP-----I-NLTELDK----KAGNLLK-KGLA-KQ---------EGDALV ID--LKDIG--FSKLL----GTGNTAKKF-KIRA---SSASQKAVEKVKAAGG--EVL-- L---------------------------PQKKAEPAKEAKPA--------------PESV ETS-------------------------------------------------------MI E--------------------RQFVSENIKEFQI----------------KEFVRDNL-S RVGLSDVKLH------RTPLGEKIVVKAARPGLVVGRAGANITQLTRQLKEHFKLENPQI EIE-EVENIHLDAAVV----------AENIAGFLERFGPQRFKSIGHRTMAEVMNTGAYG VEILISGK-I------------PS-------------SRAKRWRFY-------------- ----TGYLKKCGDVALHGVDWCYSQANLKTGVVG-------------------------- ----------IQVSIM---------------PKTT----------VLPDHI--------- ------------------------E-L------------L-PEPETV--LE--ELTPET- ---------------------------EKEE----------------------------- --------PKEKKKAKESAKKKKAPKKTTKKS---------------------------- ---------------------------SKSKEDTP-------------PKEETSPKEEVK EETAPEP----------------------------------------------------- ------------SKDNVTE-EPSKEEPASEPKKEE------------------------- --ATPEPEKKEATPQPPKEEPKP------------------------------------- --------------------------------ATEPIP-EEPEQKKE------------- EQDK------------------------------------------MKLSILSLQKKETG SVQMPDQFFE-PVRFDLIKRAVLSIQNANRQPYGAFSEAGKRASAKLSRRRR-K---YRG SYGHGISRVPRKILSRRGTHFNWVGAFMPGTVGGRRAHPPK-----AEKIWTQKINTQER RKAIRSALTAAFTKELVSERGHKVP--E---HYPFIVEDSIQQITKTKELLSHL---ETL GFAEDLARCSE--RTIRPGRGKMRGRRYKTKKSLLLV-V-S-GNCP-------------- -----LEKSAHNVLGLDIIQVQNLNAELLAPGCHAGRMTLFTQES---LKKLDQTKLFMK T-----------------------------VKVAPKEEKK-------------------- ---------------------------------------------MAKSKH---YTVKFR RKRKGLTNYKKRLELL-KSRTTRLVVRRSERNIVAQFINYKENGDNVLFTFKSSGL-KKL GW----KISTGNIPAAYLTGLQLATLAKGN--VKNAILDLGLQRPVAGSRLYAVLKGIID GGIKVPL--DETVFPS------EERLTGTHIQTHIETNKNST------QFSQYKK--DGI --TTIKPLLEECKKKI------------LGN----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKPV-KAKVTKGMNVGSIVDTCDNSGA KTIKIISVFR--QKTVKGRSPAAGVGDLFMASVKKGRPDMRKQ---VVHGVLVRQRREYR RPNGTRIKFEDNAAVVLKDDK-GNPKGTIFKGPIAKEACQ-RWPGVAKLASIIV------ ------------------------MKKSIG---VN-VPV-PKQT-----------C---- -T----DNNCPF------------------HGTLGVHGRQFVGRVISDKMTKSVTVEWER RKFIPKYERYAKARSRVKAHNPLCLN--AKQGDTVRVMETRPLSKTKNFVVIKI------ ------------------------------------------------------------ -------------------------GKEE------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MVKKEFTYTGLTLD--------------------ELKNLSLNELSERL PARQRRSLKRGL------CPGKKKFLKKTENK--------------VAKTH-HREMI--- ------VTPSM----------------------------VGKVIRIHNG--------KEF G-----------TITVLEEMIGHR----------------------------VGE----- ----------FVFTR-KRTAHSS------------------------------------- -------------PGVGA-SK-------------------------------SSSKVSVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLASVDIDKVNKTCDYIKGISEKTGVMMRGPIPLPTKKLRIT SRKSPCGDGS-------ATWDRYEMRVYKRLIDL-GIDERALRLVMRVPIPEGLNIEIEM IDS--------------------------------------------------------- -MKK--DFIAT-----WKSSTQPRKQRKYRYN-VPLHTRGGF-LDCHLSKELRTKY---- ---------------------QTR-ALRVRKGDKVKVMRG--KFK--GREEKVERVSTKL TKVFLSKIEQTKKEGS-KSLIP----------FEPSNLLITNLETS-------------- ---------DKK-RM-----------------------------------GKLTKQQK-- -----TAK---------------------------------------------------- ---------DVKPTKEVKTTKEEKKE---------------------------------- --------------------------------MAKLIRAVAWRKI--------------- -E-RPYTRKSKFR---KKSFVRAV-PHNKVVKYETGNL----QKKFPH-TVQLRSKGDI- -QIRHNAIESGRLTSNRYL-EKKLGKI-GYKLKVCIFPHHILRNNPLAS-GAGADRMSTG MKMSFGKSVGLAAQVRK-GQILFQASV---D-KSNLEVAKTAMNRAKYKM--PCSCTL-- ---------------------S-----YKEEPIT-------------------------- ------------------------------------------------------------ -----------------------------M-SLN-DPLANVLSHIKNYEQLGKKEILTPH NSKIIKKVLEIMQQNNFIGSFEEVPSGS-HSWLKINL----------------------L GRINKTGVIKPQFQITKDDFVKYEQ--------------------RFLPARDFGIIIIST NLGLMTLKEANEKRIGGKLISFVYMKKELEENLSVLCTN--------------------T MKQPLL------------ETKISLTEGVEASMDAS-----VLVVK--GPKGEVKRDFF-S P-T----IKLLV-KDGE-IIVS---AI-NAT---KREKKLLNTFVAHVKNMQNGVLEG-V VYELKICAGHFPMTVTVK---DNT--LV-VKNFIGEAVNRVLKIR--DGVSVKVDGE--- ----QIIVEGVEKELVGQTAADIELLCRRPG---FDKRI----------FQDGIYIITKN GKDLRIG----------------------------------------------------- -------------------------------------------------MTPSVRSW--- -----NTS-KEGFLGFAGYKAGMTHLLIRDDRKNALNK--GQDISVPATVIECPPMRIAS LRLYIPY--GYG-EK---IAQEIFFKP-EKE-----L-----IKKT-------------- ----RSG---P-------PQDPSA-----------------------LDSIT-------- ---PS--DFSNITITIYTQP-----KHTTIGKKKPDLFELHLGGNT-E---AKLTFAKQH INK-DIHISDVFPENSTVDLHAVTKGKGFQGPVKRFGIALKSH--KSEKGQRN--PGSL- GSWCGQGHMM-YRVAHAGQMGFHLRTQYNNLLLKTGS---DPK--DVNPKGGFLHYGNVK NNYILVKGSVPGPKSRCILLTHPIR--NT-KLEPIG------EIEYISTRSKQGR----- ------------------------------------------------------------ ----MSEHKYGFR----------------------------------------EVKENMA R----------------------------------------------------------- -----------AVIRDSP-VSTKHCIEISKHL--KNKTTERAKTILQESIAQKKAIPFTR FTN-GAGHKT-----G-----IGP-GKFVIKACTHILGLVEGVEHNALNKGL-SS-DLEI IHIASQQGASQYHY------------GR--QTRRKNKR-THVEIIV-------KEKSIKK -------PQKKQETTKSTKPAET---------------PVKEVKKDPVQPEKKQPE---- --------QKQPEKKETDSSLAGEVKPK----KEIESEPFP------------------- -----------------------------EKAKSTDPEKKE--------TEPK-LEKEQV ------------------KKEETPQR------------------------GAQND----- ---------------------MGKRLVQQA-------------RGKGSPAYKAPSFTYK- GKATT-----PRKQ-----TAE----ILDIIHCRGHSAPLAQVQFEDNSK-GCIIASEGI YVGKKVRMGE-------------KTE---LEVGNTLALKNIPEGSLIYNIESKPGDGGKF VRSSGGAAKLVTR-TK--D-QVIITFPSKKRKAFHPDCRASLGVVAGGGRTDKPFVKAGK KYFEMKKRNKYWPKVSGASMNAIDHPLG-GTRSSRK---G-R----PTIVPKNAPPGRKV GMLRPRQTG-------RKK----------------------------------------- --------------------------------------------------------MQKI RIEKLTLNIGAGKDQNVLEKGMKLLNHI-TGI-QPIKTVTQ--K--RLAAWGLRPGLPIG CKLTLRGE-KA-EQLWKKLLAAKENNLKESNFDNYGNISFGIAEYIDIPDVKYDPEIGII GLQASLTLERP-GFRIKKRKIQKKKIHHNHQITKEDAITFLQTQFKVKV--GEIQ----- --- >GCA_002686295 --------MKKR--KKNVR-QRGNN--SHGWGSKKKHR-GAGNRGGRGR-AGSGKRGDAK K---------PSFWKE---------------K-----------E-------KK-GFVS-- -LKK--KL--TT-----I-NISNLEK----FND-------------------------IK LD--LKKQG--FDKLL----GKGEPKKKY-EIKV---SYASQKAIKKIQSIGG--KVS-- LLVKNK-----------------------QLTKEPEE----------------------- ----------------------------------------------------------MI E--------------------RKFVANNMNEFRI----------------KEFVKKTL-G RVGLSEVKLK------KTPLGEKIIISTSRPGLVVGRSGANISALTVKLKEEFSLENPQI EIE-EITEIGLDANII----------AELIGGSLERFGSSRFKGIGYRAISDVINSGAIG VEIIISGK-I------------PG-------------SRAKNWRFY-------------- ----KGYLKKCGEISISGVQKAYSIAKLKTGIVG-------------------------- ----------IKVSIM---------------PSTI----------KLPDNI--------- ------------------------S-L------------N-SELQEI--IE--EVENK-- ---------------------------ESEK----------------------------- --------INEEIV-----------EKLND-E---------------------------- ---------------------------NSSKEVI--------------------KKTEIK VN---------------------------------------------------------- -------------KDKIVK----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MKLKILNLNNTETK SVDLPNQFFE-PVRTDLIHRAFLITQSNKKQPYGSDPEAGKKYSSELSRRRK-K---YRG SYGQGISRVPRKILSSRGTRFSWVGATMPGTVGGRRAHPPK-----VEKKLSDKINIKER RKAIRSAMAATIDEKFVKARGHFIP--V---NYPFVLTDKIGEINKTKKLKQVL---IKL GFEKELIRSDE--K---------------GSVGLLLVCV-E-KEENT------------- -----LKKAINNLNGFEVVNVKKLGVEQLAPGGVPGRLTVFTEMA---FLKLKNEKLFTQ NYVFSEKQN--------------------------------------------------- ------------------------------------------------MKK---TRLSYS RKIKGKTNYKKRLELL-KSRKNRLVIRRTNKYIIIQIVSYESDGDKILASVNSKEL-KKL GW----KNSCKNISASYLTGLLLGKKAEDK-KLKEAILDLGLQTHIKGSSLYSALKGVVD SGFKVPV--SKKVFPP------TDRIEGKHI----------------------------- -SEKISKEFEGLKNKI------------LK------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKPL-NARVTKGLNVGAIVDACDNSGA KKLKLISVKA--SKTVKGRLPAAGVGDLVQAAVKKGKPEMRKQ---VVLAVIVRQKKEYR RPDGTRIKFQDNAAVVLKDDK-GNPKGTIFKGPIAKEACA-RWAGIAKVASIIV------ ------------------------MKKL-------------------------------- ---------------------------------FSKRGRIFEGKVVSDKMHKTVVVRWEG KKYVPKYERYERTFTKVKAHNPEDIN--AKQGDFVRIMETRPLSKTKNFIVVEV------ ----------LN---------------------------------------------KK- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVKE-FLYKGKNLE--------------------ELKNMSLKELSEIV PSKQRRKIKRGF------SDEEKKLVEKIKMKDR-------------VKTH-LRTML--- ------ILPEM----------------------------VGRTILIHNG--------KEF K-----------QIIIQPEMIGHY----------------------------FGE----- ----------FSLTR-KRSEHSA------------------------------------- -------------PGVGA-TR-------------------------------SSSALSVR ------------------------------------------------------------ ----------------------------------------------------???????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- -MKS--KFSKS-----WSKSKQARKQRKYRAN-APLHIKSKF-LGVHLSKELRNKY---- ---------------------NKR-SLRLRVGDKVKVLKG--GFK--GEEQKVDKINLKK AKVYLEKLEKSKKEGS-KSSIA----------FQPSNLMILNLNLD-------------- ---------DKK-RI-----------------------------------QKSQGEK--- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MAKLRKAVAYRRI--------------- -E-RPYTRKSKYR---SKQYVRAV-PHNKIVKFDMGNL----KKKFDY-KVSIKAGANL- -QIRHNALESARLTSNRML-EANCGKN-SYHLKLNIYPHHILRENPLAS-GAGADRMSTG MKKSFGKAIGLAAQVSK-GQIIFEASV---N-EQFLDIAKKAITRIKHKL--PCSCSV-- ---------------------E-----IKKV----------------------------- ------------------------------------------------------------ -----------------------------M-SLN-NPLANVLSFIQNYERLGKKEVLTKN NSNLIKKVLIIMNKEGYIGSFEEIEDNK-GDLLKINL----------------------I GKINNINVIRPSYQIKNVEFEKFEK--------------------RYLPAKDFGIIIVST NKGLMTHQEAKEKGYGGKLLAYCY------------------------------------ -----M------------KEELFIPENCNVSLENE-----LVVVS--GSKGEVKKRLF-N P-L----VKMFV-DKEK-IILE---SK-KDN---KQAKKLIKTFRAHIKNLFKGANEG-H VYKLKICSGHFPMTVVVK---ENI--FE-IKNFLGEKVPRTVGIL--KDTSVKIEGI--- ----EIIVESINKEQAGQMAALLEQLTKRPG---FDKRI----------FQDGIYLIEKD GKQIK------------------------------------------------------- ---------------------------MPTIRRPRKGSMQFWPRKKAKKMTARVRSW-I- K-QK-----EPKLSGFVAYKVGMTHVARLNDDKNSHLK--GEELSVPVTIVECPPMRLFS ARFYKKI--GVK-LQ---INKEVFFKA-EKN-----L-----TRKI-------------- ----KFS---K---------SKES-----------------------LENIA-------- ---VS--EFDKITVLVCTQP-----QKAGFGKKKPEIVELALGGSN-S---EKLDFIKQN HDK-EINLRSVFDENQMVDIHAVTKGKGFQGAVKRFGISLRSH--KSEKGIRT--PGSL- GPWVRQQHIS-WRVAHAGQTGFHQRTEYNKQILLISD---DLL--SFGK--GFHKYGSLK STFMILHGSVLGPKKRTLILTKAFR--EK-S-KKHKLI----TI---------------- ------------------------------------------------------------ -----MAYKYSYQ----------------------------------------GDEESIA K----------------------------------------------------------- -----------AVLLDAP-ISTKHSIEICSRI--RNKKIDFAKNYLESVIEKKAVVRFSR FTE-GAGHKT-----A-----MGP-GKYPLKAAGIILKVIKSAESNASDKGL-SK-DLII KHASAQRASTPWRH------------GR--LRRRKMKR-THIELVI-------KEITQK- ------------------------------------------------------------ ------------IKQENKTK---------------EDV---------------------- -------------------------------KKRNNSNKKNF-------KEGL------- ------------------N----------------------------------------- ---------------------MGKNLIQQK-------------RGKGSPTYKVNSFQYL- GKASQ-----LSQA-----KGK----VIDIQNSTGHSAPLLLVKYENREK-KLVIGVEGI RVGDILEKGE-------------KAK---LKTGNSIVLKEIPVGTPICNIEGIPGDGGKF ARTSGSVARIVGK-TK--N-GILVKFPSNKQKELNPKCYASIGIVAGGGRTEKPFLKAGN KMKSMKAKGKYWPIVSGASMNAVDHPLG-GARSSRK---G-R----PTIAPKNAPPGRKI GMIRPRQTG-------RNR----------------------------------------- -------------------------------MN----------------------KMKQI RIEKLTLNIGTGKDQDKLSKAIKLLEQL-TST-KPVKTITK--K--RIASWGLRPGLPIG CKTTLRKE-DA-KKLLSRLLKAKEGHLLSSCFDNSGNISFGIHEYIDIPDSKYDPDIGVI GLQVSITLERP-GFRIKRRKLMKRKIPIKHKISKNDALEYFKKEFQIIT--GEK------ --- >GCA_013415565 -----MP-VNKR--SK----FRGSR--TCGGGTHKNRR-GAGNRGGRGR-AGHRDHRFSH YLL-----YGEV--------------------------H-N--G-------KC-GF--YN QTSR--VP--TT-----I-SIGELDQ----MATALVA-DGKA-TR---------EGDVIL IN--ADQIG--IDKIL----GSGKVTLKM-NVTA---KSFSAQAKSKIEAMGG--QAL-- AI---------------------------------------------------------- ---------------------------------------------------------MAV E--------------------RKFVAEGARRARV----------------EKHLVKEL-K RAGYGGMDLQ------RTPLGTQVTIYAEKPGIVIGKGGKVVRQLTQDLATDFGVESPQI EVQ-QVANPSFNAQIM----------AERLANALER--GWYFRKAGSSIIRRVMESGALG CEVVIAGK-L------------TG-------------SRARVQKFT-------------- ----QGYIKHSGEPVNTIVEKGYAVAVKKLGVIG-------------------------- ----------VQVRII---------------PPDA----------KLPDHF--------- ------------------------E-M-------------IKPKGKPL-PAPDIEV---- ------------------------------------------------------------ ----------TDVG-----------EDIVDD----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------LEEIIEEFAEET---------------------------------- ----IVEER--------------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MKAQILTLDGTVAG DIDLPEAFSE-EYRPDLIKKAVLALQSTRRQPHGTYPYAGIESSAVGWGSGR-------- ----GVSHVPR-IRS------GSRAAKVPQAKGGREAHPPV-----VEKVLVQRINKKEK QKAFRSALAASASEERVRARGHLFS--G---AVPVVFEDRFEELGRTADVISAL---TAA GIFPDVERSKQS-KKVRAGRGKMRGRRYKQRKSLLIV-T-A-DKP--------------- ------LKAAQNLAGVDVVTFDQLNTELLAPGTLSGRLTVFTESA---LLKLGGQ----- ------------------------------------------------------------ ---------------------------------------------MATGAR---YFVPFR RRKEGKTDYYRRAKLV-ISDRPRMVVRKSNRQIIIQLVSASIEGDHTLITASSAEL-GRF GY----TGSASNTPAAYLTGMLFAVKALNA-DYERAVLDIGLHRATPGSRVFAALKGAVT AGLDVPY--GEAVLPD------DSRVKGEHIAGYAPD----------------------- RAANLVQNVEETIDAI------------MKELR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAK-QSSTPRALSTGTRLLCADNTGA REVQIVSVFG--YHGVRRRQPKMGLGDIATVSVKKGTPDMRRK---LVRAVVIRQRKEIR RPSGLRVAFDDNAVVIVDEK--NEPRGTEIKGAVAREVAE-RFPKIGSMATMIV------ ------------------------MARDIG---LG-VRQ-PEEA-----------C---- -S----DANCPF------------------HGSLPVRGQVITGKVVSDRMMGTVVVERDY LHYVGKYNRYEKRSSRIHAHNPPCIQ--AKNGDTVKIAECRPLSKTTTFVVVEV------ ----------QQ---------------------------------------------S-- ------------------------------------------------------------ ------------------MAKKTQK----------------------------------- ------------------------------------------------------------ ---------RLPRRREEFTYRGFRIE--------------------DLRKMGMSELLPVM PARARRKVTRGL------TRGEEHLLSRFRSGDAK------------IRTH-LRDMI--- ------IMPEM----------------------------IGKEVEIYNG--------KEF M-----------KIELQPESVFHY----------------------------LGE----- ----------FALTR-RRVTHGS------------------------------------- -------------AGIGA-TR-------------------------------SSKYVPLK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIRLTGTDFKKVEMVCDRIREIAERTGVNIAGPIPLPTKRLVVP IRKSPDGEGT-------ATWDRWQMRVHKRLIDI-DADERALRQLMRTQVPKDIGIEIVL ES---------------------------------------------------------- ---------MV-----RIESKQPRKQRKARYT-APLHLRSGL-LSAPLSSELRGEY---- ---------------------KRR-SARVIKGDTVKVLRG--ESA--GTEGVVEAVDTGR YRIVVEGVSIPKADGT-EMPRP----------IDPSNVQITKLNLK-------------- ---------DAK-RV-----------------------------------EKLAEGR--- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MV-RKPGKMYRNV--------------- SK-RAYTR---------REYMGGI-PGSKIVQFDMGNL----SQEFPV-EVNLIVEETC- -QIRHTALEAARISINRKL-LKEIGRM-NFHLKLRVFPHHVLRENKQAT-GAGADRVSEG MRLAFGKAVGTAARVGS-DQIIFTTYT---T-SQYVDKAKTAMKAGGHKL--PSPSYIT- IVEKAVA----PA-------PV-----TEPSPN--------------------------- ------------------------------------------------------------ -----------------------------M-ARL-NTIADGMSALKNAADGGKPSVIIEP AGKLLGAMFRIMQESGYISGFEYLDDGR-GGQFLVQL----------------------N GRINRCGAISPRYDVPLSDLEYWET--------------------QFLPGKNFGILILST SKGVMTHEQARKEGVGGQLLGYVY------------------------------------ ---MAS------------ERRVTIPGGVSIELDGP-----VLKVK--GPKGQLERNVR-F P-Q----VSVEI-EDGE-VVVS---TA-SDR---KRVMAMVGTYEAHIRNMCTGVTTG-F EYRMKVVYSHFPIQLKLQ---GNR--IE-ITNFLGEKKSRFATIE--NGVTAKVSND--- ----EIVLTGINKELLGNSSANIEHATKIRK---RDPRI----------FQDGIYLVTRG ------------------------------------------------------------ ---------------------------MPKINTPRKGSLAFSPRKRAKSQVPKYQSW-P- E-YEG----TPVLQGFAGYKVGMTHVVMVDDHKNSPTE--GKDIMVPVTVIEIPAMKVAA VRAYARD--TYG-RH---PLTEVWTEKPDPA-----L-----EKRI-------------- ----TLP---SSY------DGEAA-----------------------RKKVEEA------ ---MAEGKVADIFVLMHTTPD----RVSGIPKKVPDLMEVRVAGGPVE---GRFEFATGL LGK-EVSLKSVIAPGSYADITAVTTGKGTQGPVKRWGIKLRKR--KHSRGGKKRHIGNL- GPWN-PHHVR-WQVPQTGQMGYQQRTEFNKRILSIGD---NGA--EITPSGGFLHYGVIR NPYVLVKGSIPGPAKRLVRIRPATR---Q-G-EHV--ARQP-AIEFVSVQSKQG------ ------------------------------------------------------------ ----MARTGYSTP----------------------------------------VSGDTVA R----------------------------------------------------------- -----------GKANELP-ISPKHAMEIARFI--KNKKTGEAVAYLEEVVAAKKAIPFRK FNH-KVAHKR-----GLS--GWDA-GRYPRKASLAYIRLIHSVTKNAEYLGL-DTENLRI IHAAANRGRAFQGMFP-------RAMGR--ATPKRRET-VNIEIVV-------QEVQ--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGHRITTQS-------------RGKGGPTYRVPSHRYK- AALRH-----A-GTSETTVKGR----VADIEHDPARHTPIALVKLEDGSR-MYMLVTEGV GVGDEVVWGP-------------EAE---VRNGNTLPLGSIPTGAYVCNIEARPNDGGKF VRAGGVQAIVIDK-SE--G-RVGVQMPSGVTKWFNSRCRATVGIVAGGGRGEKPFVKAGN KFHKMRNTASNWPRVRGVAMNVIDHPFG-GGGHQHA---G-R----PKTVGRGTSPGRTV GHIAARKTG-------RGKK---------------------------------------- -------------------------------MN----------------------PMREL YVDKVVVHMGVGEGGDKLSKGIDLMRQI-TGN-APVRSNAK--K--TNPTFGIRKGAPIS CKVTLRGK-KA-GEFLETALKIIEKRVSPGQFDRQGNFSFGIEEHTDFPGMSYDPQIGIY GMDINVVLARR-GIRVTRRHIEQRKLPKKQQVTPDDSMMFLKSRYNVEV-R--------- --- >GCA_003352245 ------M-ATRL--RKTRK-FRGSR--NHGWGQVGQHR-ASGHKGGLGV-SGQLKHHYSG MLK-----TDPD--------------------------H-F--G-------HD-STVPPH PTIT------RKW----A-SVRDLDD----LFTRY-G------KQ---------EGEKKV ID--LQGNG--FDKLL----GGGKITSAY-TVKI---NRFTASAEEKVKQAGG--EVL-- ADNG-------------------------------------------------------- ---------------------------------------------------------MSA V--------------------KNVIKDNYNMMLL----------------KDYLREQI-K EAGFSHAEIS------KTPTGTRVSLHVTRPGIVIGRKGVGIRELTEKLASDFELKNPQI SVV-EIDKPELSPSVM----------CNRMAAHLER--GTAFRRATMWTLQQIMNNGAMG VQITISGK-L------------RG-------------DRSAFEKHT-------------- ----AGILPRAGHHADVIVAEDIAHVKTAMGLIG-------------------------- ----------IRIRIAR--------------------------KEKFVPEF--------- ------------------------E-L------------KTSKAKK-------------- ------------------------------------------------------------ ----------HQVK-----------DELTGKM---------------------------- ----------------------------------------------------RDET---- -AAEK-------------------------------------------K----------- --------ARTESEQIAMEEEKIKEMEL-------------------------------- ----LDDEEENLK----------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MKVKALSITGSADG DVELPQVFET-PIRKDLIHKAYVNLDTHHYQPKGTHPTAGMDVVARSNDP---------- PTGHGSARIAR-MRG-GGGGRQGEAGGVASVRGGRQAHPPN-----VERVIYKKVNRKEN KLALCSAIAATASKELIQKRGHKIE--GI-ESFPMVVSNEIENISKTKDLLKVL---DSL KLTQDVERLSK--RKSRTGKSALRGRGKKIGKSILFV-T-K-SADK-------------- -----IAQACGSIPGVEVRTANQLSVLDLAPGSDPIRLTVYSKNA---IEEISKIKSTHM EIMVKVK----------------------------------------------------- ----------------------------------------------------MAYSQILR RLREEKTNYRKRKTML-MGKRPFITVQITNENTQVQIHTPEMTGDKVIASAHSHYL-LKK GW----KGSRKNIPAAYLTGYLAGKKAVGK-GSKSAILYTGTR--RYTQRMAAVLKGVVD AGLEIPA--DPESFPP------EERITGQHLTV------KNDV----NQFKS-------- ----------QIDSEVK------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------MSQGRSR--GKAKG---VAEF-RPYVPRALPVGAQIICADNSGA KILEIVMVQK--TKTRVSRLPAAAVGDFVNVVVKKGPAELRKQ---IYGAVIIRQKYPIR RLNGVRVAFEDNAAALMTPE--GEMKGTDIKGPVAAEASE-KWPRLANLASMVV------ ------------------------MTRNIG---LP-VKT-PEKE-----------P---- -EA--WDKKNPF------------------NGTLAIRGKLFEGTVVKANAKNTVVIEKES PIYFSKFKRYARGKSSIHAHVPSNLD--VKQGDRVLAAECRPLSKSVAFVVVEV------ ----------KE------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MVKKFEYRGMPLT--------------------ELEGLSLENLFKLF NSRQRRSLTRGI------TDGKRKLIEEIKAAKA-----GKSK--NAIKTH-VRDLI--- ------VLPYM----------------------------VGVTVNVFSG--------KEF R-----------PVTIIPEMIGHY----------------------------LGE----- ----------YVITN-KRVTHGA------------------------------------- -------------PGVGA-SR-------------------------------SSLYVPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------TQSARIKLTSTSLPKLDGVCGEIMGIGKKTGVRVKGPTPLPVKRLHVA TRKSPCGNGT-------ETYEKWEMRMHRRIIDI-NADDKAIRQLMRLKIPDDVYIELSL T----------------------------------------------------------- -------------------MKPTKMRNNQIYR-ASLTTRSNQ-LGSTLSKELRKKY---- ---------------------GKR-SVRIIEGDAVKVIRG--EYK--DVDGKVASVSVEQ NSVAIEGIKKEKGQGD-KFDVL----------IHTSNLMITSLNTS-------------- ---------DSW-RM-----------------------------------SKLEGKKPQN VKKEMPKEVKEEAKKPEP---------KKEAPKE-----------------------KKT DIEKKPTKKESKPAKKKEKSE--------------------------------------- ------------------------------------MHGANYRKS--------------- -NGQPYAR---------KKYIKGK-PQIKIAKFQTG-K----MGDYDF-CVQLLVNEKI- -QIRHMAIESTRLAANKTI-EQVTGET-GYYSRLRVYPHVLLRENKMIA-TAGADRLQEG MRRAFGKAVSLAARVKQ-GQVIYEAHV---K-KEHLEHTKKALKSACVKL--PGTPTI-- ---------------------K-----VIPLK---------------------------- ------------------------------------------------------------ -----------------------------M-PAT-NILANLFVTIYNTEARRKNECLVYP TSKLGINVLKVLQKDGYIGEFEHIDDKR-GGKFKISL----------------------L AKITKCGAISPRFKVKKDEYAAWEQ--------------------QYLPSYDRGMLLVTT NQGVMSHHEAASKDLGGFLIGYVY------------------------------------ MSTKQL---------EKFATSVKVPEGVKVSLDKH-----MLLVQ--GPLGKTYKNFK-- ----KIPVDIKV-EGNN-VSLK---AL-DTR---KKDYAILNTSRSIIKRLCEGVVSG-Y TIKMKVVFAHFPITVKTK---DDK--VL-IENFQGERSARVCQII--GKTKVNPKGE--- ----DVIITGHVLTEVTQTAANIEQATKVKG---KDHRV----------FLDGIYIFEKT SGIEK------------------------------------------------------- ------------------MG-------HRKNSQPRRGSLAYLPRGRAKSFEARIRTW-P- D-VNSE---EPKLLAHVGFKAGCIQVVSIDDREKTPNH--GKQLVSLGTVLVTPPITVLG IRGYSNS--TTG-LH---AEFDVYSEDIPKD-----I-----AKHI-------------S L---------KNK--------EGA-----------------------LEKAEKM------ ---LG--RIKEIFALVAVSP-----NVIGIEQKKPYIFEAAIKGGDIQ---KQFNYVKEL LGK-EVKIDQVFELGGSVDVAAITKGKGWQGVIQRYGAKKKQH--KSRKTVRE--LGSL- GPIS-PQNVM-YTVPRAGQMGLHQRVEYDKRILIMNN--TDDKKLEINPEGGYKHFGLVK GDYIVLKGSVPGTYKRMVKLRSQVR-----N-VPPK-ITKP-NILEIVV----------- ------------------------------------------------------------ ----MGRFDYAFQ---------------------------------------NYDTTKHV R----------------------------------------------------------- -----------ASLREKQ-ISHKHAREVSKQI--KGMTIEKARDYLTSVINKERAVPFRR YKT-NVGHRS-----D---PGVMA-GRYPQKTALEFIKMLDNLESNAEYKGM-DLDRLKI VNATSHKGILIKRFTP-------RAMGR--ATPKNNVL-THVELVA-------QEV---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRPLVRR-------------RGRGGMQFRATVTGKV- ARSKY-----PSFTLSEQHEGK----VIDLVHERGRDAPLAKIRFEDGSV-SFVPAVLGT KVGDTLEFGL-------------KSK---IQDGNVISIQNIPDGTIVCNLEKQFGDGGSI VKSAGTNATIFSH-NE--E-GVTVKLPSGKFATFNPKNRAMIGTLSGGGTSERPFMSAGR KWRNFRSRGRKYPIVRGVAQAAYVHPHG-GGRHQHV---G-Q----SSTVSRDAPPGAKV GSIAARKTG---------RARIKERK---------------------------------- -------------------------------MSQT------------------ENIMKKI SLDKVVLNMGVGKSGDAIDVAKKALDQI-SGK-KSCARDAK--E--TQRDFGVRKGEPIG VAVTVRGK-DA-EELLKRLLQAKGNQIKGRSFDDFGNFSFGILEHIDIPGIKYDPNIGIL GLDVAVNLTRP-GYNIRKRSKHKASVGKTHRISEDEAKEFMENQFGAVI-V--------- --- >GCA_002687735 -----MV-VRRR--RKKNK-VRGQR--THGGGGTKNRR-GAGSRGGVGK-AGSHKHKFSK HYVD------------------------------------F--GV------KK-TLKPK- --KK-----ENT-----I-SLAYIND----NVEKWLA-DGKV-KK---------DGSIIV ID--GKAFR--FGKVL----GNGIINHKI-KIEN---ANASKMAREKIQKAGG--NVS-- IEE-------------------------YSKAEETEEE--EMEK--------DENKADEA EA--------------------------------------------------------MI E--------------------KYFIEQGLKKLEL----------------DDYLSKEL-D RAGFTKSEIV------KTPLVTRIVVNVTRPGLAIGKSGSNITQLTETIGSRFGIDNPQL EIR-EIESPELDAQAV----------ANKMKALIER--GFSWRSIVFKSVNETQKSGAQG LEIILSGK-IT----------GKA-------------GRKRKQRIA-------------- ----YGYLKKVGEQA-KLVDYGKADAYPKVGAIG-------------------------- ----------IKVKIV---------------HPDT----------VFPDKE--------- -------------KIT--------DYIKTKEEVV--EETTEEKETKSE-KEEVKET---- ----------------------------KEK----------------------------- --------TEKKPA-----------KEEKTE--ESP------------------------ --------------------KGKEKPVKEKKEVKE------------EKKEVKKE--KVA TEVSP------------------------------------------------------- ------------EGEKK-EEPKKEETKE-------------------------------- ----KKEAKE---ESK-------------------------------------------- --------------------------------AETK------EEKDE------------- ANKE------------------------------------------MKARVLGLDGKKGS EVTLPKQFSA-DVNKELIKRAVQAIQSAGVQNSFPKPEAGRANTAEYIGARH-K-PNIHR TINVGHARKPR-LKN-RRGVLSGHVASIPAVVGGPRAHPPK-----PNKEWEEKINKKEK RQATESAIAATGKKELVKERGHKFG--EK-LEFPIIVEAKLENLTKTKDIRDAL---KAI DIYQDVEKALSK-RQLRPGKGKKRGRKYKKRKSVLIV-V-E-NPEK-------------- -----VYKAARNLEGVDIISAVNINADLLAPGTLPGRLTLWSENA---IKELAGEKKETK TKEKA------------------------------KVEAKA------------------- ---------------------------------------------MSSGPT---YNVKFR RRRESKTNYKKRLGLL-KSNKDRLVVRKSNNSTVCEIVTYKTEGDKVRAHFTTSSL-KKL GW----KGHTGNIPAAYLTGYACAKKAMKD-KVGEAVLDLGLVTPVHGGRIFGALKGAID AGLTMPS--DEKVFPK------DGRISGKHIS---------------------------- --EDVEKNFEETKKNIDKE---------LGE----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAI-SASPVRALGFGSICTCADNSGA KEVRIIAVYK--YHGRKGTHPRGGVGEMCNVVVKKGKPEIRKK---VEKAVIIRQKKEYR RPDGTRVKFEDNAVVLVDEK--GLPKGSEVKGVVAKEVGE-RFPKIAGISAGVA---MSE ----------------------------------------KETK----------AI---- ------------------------------SDSHSVRGSIFVGKVISAKAPKTVTIERKT TQYIRKFERYKKSKSKISAHIPEGME--IKEGDVVKIGETRKISKTKSFVVLEI------ ----------V-------------------------------------------KKGEQ- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVKKEFTFRGKTIE--------------------ELKGLSIIQFAELC PTRAKRSLLKGI---------DEHFLKKVVKAQETL-AAGKYP--KPVKTH-NRDNI--- ------VVPSM----------------------------VGITVGVHNG--------KDF V-----------NVEVKEKMLGHY----------------------------LGE----- ----------MVLTR-KRLLHGK------------------------------------- -------------AGIGA-TR-------------------------------SSTAITAR ------------------------------------------------------------ ------------------------------------------------------------ ------------MQTARLKLSSGDFTELEDICGKIQEVAKRTGARHSGTIPLPTKKMLIP TRKSPCGGGT-------ETYEKWQMRIHKRIIDI-QADETTLRRVMRVEIPEKVHLEIEL KEKNK------------------------------------------------------- -MEV--------------TSSKPKKQRKWHYT-KPLHLQQKE-FAMHLSKDLKKSI---- ---------------------GKR-SLDGRKGDTVKVMRG--NEKFVGKQGVITAILRQK KQVLIEGITRKRLDGT-EIQVP----------FKASNLRIVNIEDK-------------- ---------DNR-RLKG---------------------------------KKVAKEAKKV ------------------------LP-------------------------------KVD AQPTAATVEEKVKEDGK------------------------------------------- ----------------???????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????----------------- -----------------------------M-SRN-DPVADALINLKNTENASKKECVIRP ASKLLKEILKILQEKGYIGTFEFIDDGR-EGLFKIEL----------------------I GKINECRAIKPRYAVKKAEYEKFEK--------------------RYLPSYDIGTLIVST PKGVTTHNKAKEMQTGGRLLAYVY------------------------------------ -MTEKL------------VETIEIPEGIQIELNGN-----DIKVS--TNGKENTRHFK-S T-E----VLLKK-ADSK-IEVW---AK-SER---KNVLAESKTIGSHIKNLMHGLHED-F VYKLEVVYSHFPMTVKVN---DGI--VE-INNLAGGKKPRKAKILG-K-TKVEVKGK--- ----EITVSGHNKENVGQTAANMEQATKIKG---KDIRV----------YTDGIYITEKA KTV--------------------------------------------------------- ---------------------------MVGGHKPRSGSLAYYPRVRAKRQLANFSTY-P- T-IKTE---SSKPINFFGFKAGMTTIFGKNAQEKSVNF--GTETAIPATIIECPPIKIIG ARVYKKT--TDG-LK---ALGEATIEKPGKH-----L-----RDKV-------------- ---KAFK---KQG------KKQTKTTKGSSAEGTSKSEGTKT--YSKFEDLEKF------ ---KE--KAVKVVLLSELQP-----SATGIGKKKADVAELTLNGTI-E---QQLAFAKEK FGK-EIRINDVFEVQEFIDVRAVNKGKGFQGPVKRFGIKIQRP--KA-KKHRA--VGSI- SPWH-PATVM-WTVPRPGQMGYHTRTEYNKRILFVE---NDPK--TISPPQGLVNYGILK NDFIVVSGSVPGPAKRTIALRHAIR-KVDKNLAKYT------DLQLPYGTEEKVEAVKEE KKSEPAKEKKTEEKVEKKEEAKPEKKEVKEKVKEAKAEAKEESKGAEKK----------- ----MVKKTMQVQ--------------------------------------KI-NSKKTA Q----------------------------------------------------------- -----------AMMKNKP-VSLKYSTEIISNI--KGKRVDKSLAWLQRIINEEEFLPLRK YNK-KIGHKK-----GASKGFTKI-GRYPKRCLTAFVELLESVQANADYKGL-DSENLLI THMFASQGFQRASYQS-------Q--GRISGKRRQNKS-THLEIVV-------MEAK--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MPKRLKSQR-------------RGKGSPVFVA-TNKGA- APAQY--VDYTE-MTEKTLKGE----VVGLIHDPARTAVLSKIEFDNGSQ-SYSVAAEGM FVGQKVEYGT-------------EAD---LQVGNVKPIGNCVEGCPIFNVEKTPGDGGSL VRSSGTYALIVTK-DK--K-TVYVKMPSGKTMELNPKNRATIGCVGSGGRREKPFVKAGK KHFAMRAKHKKYPTVRGIAMNAKDHPFG-GANH-HP---G-K----SKSTSRRAAPGRKV GDVASSRTG-------RKKK---------------------------------------- ----MDDNK-----------------------------------------------MKEI KVEKVTVNMGVGQKGEELKKATTILETV-TGA-KPTLTKCK--V--KQPDWGLRPGLTIG TKVTLRGE-KA-KKFLTEAFLAKDKKINKKSFDKQGNFGFGIKEYIDLPKAKYDPKLGIK GLDVLVTLERP-GYRIKRRKIDKSKILHSHLIHQNEAIDFIKENFGVEV-E--------- --- >GCA_014727985 ------M-AHGS--RKTNR-LRGSR--THGYGNAQKHR-GAGSRGGRGM-SGSKKQKWAR ISK-----NMKG--------------------------Y-F--G-------KK-GFKRHK TTVE--DV--KT-----M-NVGYLSD----HIGRLVS-EGAA-TE---------SKGAYT ID--LAASG--IGKLL----GAGKVESKL-NITV---NSCSPRAREKIEAAGG--TVE-- VQKAED----------------------EF--LEAQSGEEAEDS---------ESGE--- ---------------------------------------------------------MAI E--------------------RHFIQEGVIRSEI----------------ESFLRNEL-N RAGYSGITIQ------KTPLTTRVVLYVEKPPIVIGKKGSRINSLTNMLKEKFGVDNPSI DVQ-KIEKPTLDPNII----------ARRIAVALER--GMNRRRIAYKAVRAVMSSKARG VEIILSGK-IV----------GKG-------------GRSRNEKYS-------------- ----EGYMKKAGD-SLKLVRIGSTQAYLKAGVIG-------------------------- ----------VTVKIV---------------PPDT----------KFPDHI--------- ---------NVLKGVK-EE-----E-IEGE--D-------TKKKAKKK-TKKKAKK---- ------------------------------------------------------------ ---------AKKTA-----------EKKDDP----------------------------- -------------------------------------------------------GEDK- -EETG------------------------------------------------------- --------A------SKADDGSEK------------------------------------ ----AEKE--ESNA---------------------------------------------- ------------------------------------------------------------ -----------------------------------------------MVNVYLLDGKVKG KVDLPKVFQA-PHRPDLIQKAVVAEQANVRQPYGVSSLAGLKTSADYFGSRR---RTYRQ TINRGMTRLPR-VKS-GGG-GLGQVRRVPQSTGGRRAHPPR------GRDYTRKLNRKEY MIALHSAIASTASRKLVEGRGHTAD---V-KEVPIVVEDKIEGLKHTKDVLKMF---KSL GLDGELAS--------------------KKKRKMLIV-V-G-EDKG-------------- -----IFNAASNIEGVDVATVNDLDVELLAPGTQAGRLTVWSEAA---VKRIGEDGTA-- ------------------------------------------------------------ ---------------------------------------------MATGAT---YSVRYR RKRQQKTDYKRRLNLL-KSETTRFVVRPTNKNTIAQLIEYSEDGDKVVAQANSGEL-KKM GW----AHSTSNTPAAYLSGLLCGVRGREK-GVEKAVLDTGLYPMIRGSRIYAALKGLID SGVESGA--DEVIFPA------EDRIRGKVIAAYVE------------------------ RSKNIEADFDKVKASI------------LKSSK--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------MPKNLPLGKAV-SASVTRALPAGARLHCADNTGA KEIEIITVRG--YKGVRSRMPKGGVGDMVVATVKKGRPDIRKQ---VVHAVIVRQKQPYK RVNGSRICFEDNAAIIVSEE--GMPKGTEIKGPVAREAAE-RWGKIGSIASIVV------ ------------------------------------------ME-----------C---- -S----DRNCPV------------------HGNLATRGMILEGEVVSDKMQDTVVVKRER LVKVKKYDRYMKSTSRIPAHNPPCIN--AKQGDKVTIMECRKLSKTVSFVVVGK------ ----------AG-----------------------------------SEPAAES-PEKKT KKKTKR------------------KKAKKASKKGVNDG---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKEFKYRGYKIE--------------------ELQKMSHDEVLELL PSRARRSLKRGL------TEQQQKLLKKVRKARETG-QKGA------VRTH-CRDMV--- ------ILPEM----------------------------VGVKFAVYTG--------KEF S-----------EFEAKTEMIGHY----------------------------LSE----- ----------FTLSR-RPVKHSA------------------------------------- -------------PGVGA-TR-------------------------------SSLFVPIK ------------------------------------------------------------ ------------------------------------------------------------ ------------MEKARIILIGKEVDQLEDVCTQIVDVTKKTGTKYSGPVPLPTKKMRVT CRKSPDGEGT-------GTWERWSMHIHKRIIDV-SANERSLRQIMRIQVPDGVHIEIEL TK---------------------------------------------------------- -------MKMK-----RPSSKQARKQRKWVGE-APLHMRHRL-VSAALSKDLKDKY---- ---------------------KKN-SMPLRKGDTVKVMRG--SVK--GHVGEVMKVDLKT YKVYVQGVTAKKSDGT-DVERA----------LEPSNLMITELHEE-------------- ---------DKE-RR-----------------------------------DALSRNME-- -----AE----------------------------------------------------- ------------------------------------------------------------ --------------------------------MASLRPAKCYRWD--------------- -S-PAYTRVSNNP---SDSYITGI-PGSKIIHYDMGNP----TGDFNT-KVEIVYNDKC- -QVRHNALEATRILVQKRL-EKLVGVT-NYHFKVNVFPHHVMRENVQAS-GAGADRVSEG MRRSYGKPIGRAARLKP-GQALFTVRFN--KTDTRLKTIKKALRLASNKL--PGDKSV-- ---------------------I-----VSELKK--------------------------- ------------------------------------------------------------ -------------------------------MRH-DPLNDAISTIKNAERTGKSECMLKP ATKLLVSVLHIFQENGYIGEYEVEGNRR-GGSVRVKL----------------------I RHINDCGVIKPRFPVKNQDFIQWEK--------------------RYLPSRGFGLLVVTT PQGVMSHEEAKDKGIGGRLIAYAY------------------------------MSNTDK KHHGEL------------E--VGLVEGVEVDAKGR-----TITVK--GPKGELTRKFR-- ----EDFISFKP-HDGR-IRIQ---AK-SKRLPLRKQMAIMGTIAGHIRNMMEGVTDG-F TYKLRVVYSHFPMKAMVQ---GSE--FV-IDNFLGEKHPRRTKIL--DGVSVDVKGN--- ----EVVVSGIDKESVGQTAANIEQLTRIKN---LDVRI----------FQDGIYIIEKA GKPVL------------------------------------------------------- ---------------------------MAKIHKPRAGSRAYRPLKRAKSEKPRIHSW-P- A-GKG----DSKVLGFTGYKAGMTHCIAVDESKDSPTS--GSEVFVPVTILETPPMKVVG VRVYRKA--YGG-EQ---TFTDIWCETPDES-----V-----KRRA-------------- ----STP---KKK-----GNPDKK-----------------------IAEAEKK------ ---SG--EISDVRLVAHTQP-----ILTHSPKKTPDIMELAL-SGDVP---EKLAYAKEV LGR-EITINDAFSESEFVDVTSVTKGKGFQGVVKRYGVKRQPR--KASGKRRH--LGTG- GSWT-PTKKL-WVEPQPGQMGYHTRTEHNKLILKIGE---DGG--EVSPAGGFLRYGPVK SSYVMVYGSVPGPSKRVVRLTQPRR---S-H-KEV----SL-TLKSVDLSSKQGA----- ------------------------------------------------------------ -----MDLKYSVK---------------------------------------P--EEGAV K----------------------------------------------------------- -----------AMGRDMN-VSFKDLVVVADAI--RGKKVSKAIEYMESVVELKNPVPYRK HNK-GVGHRK-----GKE---VKV-GKYPQKAARHVLAVLRNLAANAEYKGY-DTEKLKL THVQAQKGLARLRRKP-------K--GR--WALWETQY-SHIQMIA-------KEA---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRHITQR-------------RGRGNPRYRSPSHRYK- GSVKYP----RI-DYKGRISGQ----VIEFDHDPGRTAPVAKVLLEDFTT-VQLIAPETV TVGQTIEFGS-------------GAS---VSNGNVLPLKNISPGTGVFNLEVKPGDGGKI VRSSGSFALIVSH-DKSTG-LTQVKLPSKKTKFINSDSLATVGRVGGGGRKDKPMLHAGQ MYYRKKAKGKLWPVVCGRAMNAVDHKHG-GGRHPHV---G-R----PTTVSRNAPPGRKV GHIAAKRTG-------KKKRG--------------------------------------- -----------------------------MMAN----------------------VMEQP RIEKVVINIGVGESGERLGKAEKLLEKL-TSR-KPTRTISK--H--KNPTWNVRKGEPIG CKVTLRGG-DA-VEAIKRTLYAKDNMLRPGNFDVSGNVSYGIQEYIDIQGLKYDPEIGIF GMNVNINLERP-GYRIGRRKQRQVKVPDHARVTRDEAIKYMEKEFGVKI-EEEE------ --- >GCA_007133845 ------M-RRKT--KKFRK-IRGIS--T-SRGNSKRAR-GAGNRGGRGK-AGYGKRAGHK KTKLRSQ---PSIKKDK-------------------------------------GFTSIK KVKDF-KP--KK-----I-NVGDLDK-----LSYKIG-NE-------------------- ID--LKKLG--YDKLL----AKGQVRTKL-IIKT---DNFTKSAKEKIEKAGG--KVI-- SE---------------------------------------------------------- ---------------------------------------------------------MVV E--------------------RKFVEDKLRESAI----------------TEYLQNSL-E GVGFSSINIK------KTPVGFSVIIHSSKPGLIVGRGGSNIKEIQKTLEKDFNLESPVV DVR-EVEKPELDPNIM----------AGRVGFQLKRYGASRFKAIGHKILEQILNSGALG AEIRISGR-V------------PS-------------KRARSWKFY-------------- ----GGYLPKCGEVAKEEVLQGFFKVKLKPGVVG-------------------------- ----------VYVKIL---------------PPNV----------RMPDVV--------- ------------------------Y-L------------K-EEKKKIF-VE--ETVEED- ---------------------------VEEN----------------------------- --------NKNE-----------------EKVIL-------------------------- ---------------------------KDNEK---------------IENENEKSEKEIL KEEPTE------------------------------------------------------ -------------------EEPAEEEP--------------------------------- -----TEESKEESQEG-------------------------------------------- ------------------------------------------E----------------- ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????----MAKGPT---YVVKYK RRRKGLTNYNKRLKLL-KSDKLRFVVRASKNSTNCQLIEYHPDGDKTLINFNSLEL-KKY GY----KGHTGNISAAYFAGFACGLKAIKE-NKKEAVLDTGLHRLTKGCRVYAALKGAVD AGLKINH--NEKIFPN------ERRIQGYHIAEYAKILASNNPEKYEMLFSNMLK--KGV KPEDFVEHFQEVKKRIEGE---------HG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAV-KANVTKALQVGSRIKIADNSGA KIVEVVSVKG--YKGVKGRLAKCGVGNIFIGAVKKGNPDTKHT---LLPCVVIRQKKEYR RKSGVRIKFEDNAAIVMKDLKEGSPKGTSIKGPVAREVVE-RFPLITRISKMVV---MAQ KEM---------------KKEKS---KGIG---IP-GIEIPKNN-----------C---- -D----DINCPF------------------HGNLKIRGRIFEGIVESIKPSKTAVVRWER RVFCPKYERFEGRFTKVSAHKTDCLN--IQKDDIVIIGECRPISKSKKFVVLGK------ ----------VE---------------------------------------------K-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------NE----- ---------------------------------------NKKI--KKIKTH-CRDLV--- ------ILPEM----------------------------LGLTISVYNG--------KEF V-----------DVEITPEKLGYF----------------------------LGE----- ----------FTYNR-TRVQHSS------------------------------------- -------------PGVGA-TR-------------------------------GSTFVPVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MSKARIKLSSTEPEKINEVIRQIEEIAEKTKVKYSGPIPFPTKGLKIP TRTSPDGEGR-------ELFETWEMRVHKRLIDL-DVDERALRLIMRI------------ ------------------------------------------------------------ ----------------MKKTKNRKKQRKRIIP----YVKTKG-LSSHLSKSLIDKY---- ---------------------KIK-TLGLRKGDEVKIVRG--KFK--DKQGTVDNIIPKK EKVFVSGVEIEKQDGT-KSKVS----------IHNSNLIITSLNLK-------------- ---------DKL-RK-----------------------------------EKLEKKSK-- ------------------------------------------------------------ -----KVLKNEKT----------------------------------------------- --------------------------------MAKLRKASCYRKI--------------- -E-RPYTRKSRKR---EKSYVRGA-PYSKIVKFDMGNT----KRDFSY-RVKLISKDDV- -QVRHNALESSRVAVNRIL-VRKAGKN-NYYLKIRTYPHHVLRENPIAA-GAGADRVQTG MAHSFGKPIGLAAQINK-GQEVLTVDV---D-EKHIKVAKEALKQAIYKC--PFKGKI-- ---------------------E-----VDKKAK--------------------------- ------------------------------------------------------------ --------------------------------MV-DIIAQALSQIKNAEKKGVQTCIVKP VSKTLRNILDLMQKEGYIGEFEIIDDGR-GGFIKINL----------------------L GAINGCGAIKPRFSTSLANYQNFEK--------------------RYLPAKKYGVLIVST TEGIMTQEEAKEKKQGGRLLAYIY------------------------------------ -----M------------EEEINIPENVEVRKEGG-----VLFVK--GKLGEISKRLS-H P-K----VKIEV-SDNV-VKVF---SD-LET---RKSKRLINTFVSHIKSLFKGIQEG-Y TYKLKIVYTHFPTNVKLE---GDK--II-IENFIGERSPRITKKL--PGVEIKIDKK--- ----DITVSGPDLQAVSQTAANLERVTRIVG---KDKRI----------FQDGIYITEKG K----------------------------------------------------------- ------------------MG----H-QINKPKYPKRGSRAFVPRVRAKRIYPKIKNW-P- V-TN-----ETKLLGFAAYKAGMAEIIFVDNSPTSITK--GEEICVPITILDAPKIKIMA IRFYKKD--DRR-FKK--VFTEVWTDKIDKD-----L-----KRKI-------------- ----SYP---KKK-----KNSEEE-----------------------LNNIN-------- ---I-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------EKI---------------- ------------------------------------------------------------ ----MGKKKLESIQQK-----------------------------------KKEKLDRKA K----EK--KEEEVVEEK-SKEEKE--------------KPKKKVEIKK------P---- -KVSEAK----GRGEYLP-ISSKISVEVCRAI--RGKNVEKAKNILKGAIEKKKPIRYFR YKK-DTPHRK-----G---KGFGA-GRFPVKVSKYILGVLENAIANAKYLEL-DPDELYV KRSISNRAVSKESQ---------R--GRY----------TNLEIVV-------AKKTKKV ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------KK--------------------------------------?? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????????????----------- ---MTTEKN-----------------------N----------------------PMKEI EIEKLTLNVCVGESGDKLENAKILLERI-SDS-NVIYTHAK--K--RVPTWNLRQGLAIG VKTTIRGE-KI-HDLLKRLFEAVENNINPKNFDKEGNLSFGIKEYIHIPDVKYDPSLGII GLDVCVTLKRKGGYRVKRRNYKKSVVGKKHRISKEESMNFFKENFNISI--GEKKRRLW- --- >Bin665_genes -----MK-TKKR--TKTSR-IRGAR--TCGYGFRQKHK-GHGNSGGQGM-AGSGKRADHK KQKALM-----------------------IANKAGVKEY-F--G-------KK-GFTSRR VGKK--KE--KK-----I-N----LRD---IKEKYGD-K----K---------------E ID--LK-----GYKIL----GNGEGFKAV--IKA---LSASKGAIEKMKERGG--EIV-- IKEKKL--------------------EKEKEKK--------------------------- ----------------------------------------------------------ME E--------------------RKFVEIRKEEHSI----------------KKFIRRNF-G MGKVSSVRIE------YTPVGEKIIIATHKPGLIIGKRGETIAKLTDVLKRRFKMENPHI DIE-EILNPEFDAQLV----------ADDIALSLERFGAMRFKAIAYKILSRIQGAGAMG VELRLGGK-L------------PS-------------DRAKSWRFA-------------- ----YGYLKKTGDTA-KVVDRAESTAMTKKGMVG-------------------------- ----------IKVAIL---------------APNT----------KLHDKF--------- ------------------------D-I------------D-EDLINE--IKKNAVF---- ------------------------------------------------------------ ---------EEEVV-----------EE--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------KTKKT--------------------------------------- -----KKVKK-------------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MKTKLIDKAGKAGK EIELPSNFSA-DVRKDILLKVFEA--TKRMQVMGSKIGAGAGYSASGILRHR-R-HVWKT TYGKGISRIPRKIFSRSGSSFNWEGATVSNTRGGRKAHPPK-----TEKKLFKKINKKEF LIAMNSALAGSVGEEYLKEKYGK----STKI-LPIIFEAGILDV-KTKEFLAVI---KGL -FGDAYENVLKK-KSVRAGKGKTRGRKYKSNAGLLFV-V-G-KDEKM------------- -----------NRKGIDIVRVGDLGVGDLAPNGVAGRFVVYTEKA---VKEIGEVFK--- ------------------------------------------------------------ -------------------------------------------------MT---LRTIKK RRKQGKTDYKLRLGLL-KSGKARVVIRMTNKYVVVQLVESVEAKDKVIAGVSSKNL-IGE GWDKKFSGSLKSVPACYLTGLLMAKRI----KDGDVILDIGMAINKKGGRIFAVVKGLVD GGVKLKV--DKKIFPS------DERVKGEHLKD--------------------------- ---EVKNIISKVLEKVK------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAI-SARATRGLNIGAKLEACDNSGA RIVRIVGVKK--AKAKKGMQTPARIADWVKVSVRAGDPKMKGE---VFDAVIVRQKRAWR RKTGERVAFSNNAVALLKDDK-GNPKGTQIKGPIAREVQE-RWKEVAKLASVVY---MAE -----------------------KKKEKIEK---------GVQK---------VSCA--- ------DKFCPVHG----------------SKPLKLRGRIFEGKVIK-KFVGRVVISFER MFYVRKYERYEKRRTKLHARLPDCLRDEINIGDVIQIAECRPVSKIIHAVVVKK------ ----------VR-------------------------------------------GGGE- ------------------------------------------------------------ ------------------MA---------------------------------------- ------------------------------------------------------------ ---------GIVVSGREKLYRGKSLE--------------------DLQKLDVREFAKFL KSRERRFIMRNF-------NVIEEFIKRCEKKILKK---------KVIRTH-DRSLI--- ------IVPSF----------------------------VGWTIGVHNG--------NGY V-----------QVKIVEEMLGHR----------------------------LGE----- ----------FAMTR-KAVKHGA------------------------------------- -------------AGVGA-TK-------------------------------SSAALSVK ------------------------------------------------------------ ----------------------------------------------------???????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- -MKN--KFSTK-----WKGSRQPRKQRKYLAN-APLHLKRKM-MAAMLDKVLRNKY---- ---------------------GMR-NIEVKKGDTVKVMRG--KMS--KKQGKVADVDLRR MKVSIEGLQAGKKDGS-KVNVW----------FHPSNLKIMILDLE-------------- ---------DGK-RM------------KRKKDVKVE-EK-----------KVEEKKEE-- -----KKESKVN------------------------------------------------ --------KEKKNVPEKTSNA--------------------------------------- ---------------------------------MALRKAGAYSKK--------------- -HARPYTRKSKVR---QKSYIKTI-PNSMVVKFRMGDLKGFRDGKYKI-ILSAVSKDKV- -QMRDNSIEAMRQFLNRFL-TEKLGKE--FYFEVKPYPHHILRENKMLT-GAGADRMQTG MSQSYGKSMGRAAFIKP-GQTVFKIGV--TN-DKHEIEARKLIKSVKARL--PCSVSV-- ---------------------E-----VVRS----------------------------- ------------------------------------------------------------ --------------------------------MSQDIVADGLNAIMNAKRVGKTQVEIKR VSKVLIGLFEMMKKYKYI-EFEMGGDEK-KPSVVVKF----------------------L K-LNECRAIKPRFYVTVDEIEKYLR--------------------RFLPSRNFGVLVIST SKGLMTDEEARENKVGGALIAYFY------------------------------------ -MKLDI------------QKIIEIPEGVQVEVKDN-----EVVVK--ADGKELKKVFG-L G-K----VKIEK--DKD-LKVG---CK-KST---KRESKMIGTIAAHLKNMVQGVKED-F VYKLEIANVHFPMNVKVE---GDK--VH-IKNFLGEKIDRVADIV--EGVKVDVKGN--- ----EITISSHDKENAGQTAGNIEKATKVSG---RDRRI----------FQDGIFITEKP GRGI-------------------------------------------------------- ---------------------------MPKRHRPRAGSLQFWPRKRARRILPSV-NW-K- G-VGK----DGGLMGFICYKVGMVSVYAKDMTEDSMTK--TKRVVFPGTIVECPEVKIYS VRFYKG-------GK---VLRD-LVVGFDDE-----L-----KRKV-------------- ----KGV---K--------DV-KK-----------------------VDDFKD------- -------DYDDVRVIVYSDV-----KKTGI-KKKPDMIELGLGGSK-E---DKLKWIKEK IGK-GIGVGEV-FSGGLVDIRGVTKGFGFQGPVKRFGISLKAS--KSEKGQRR--PGSL- APWN-PSRVT-FRTAMAGQTGYQTRIAYNNFILQVGK--ISEK--DINKKGGFHQYGNIK TDYVVLMGSVPGVKKRALLMTQPIR---E-S-KKQS-KKKF-EVLELR------------ -----------------------------------------------------MTEKEYS --PTMKEKKVSAKKVE-KPVESMKV----------------------KEEVKE---EKKT E----V--------------KKEEK----------------KKKVEKVEIK--------- -PKMSAV----VNGQSLH-LSLKHCKAICRMI--KGKSPERGAEMLIEVSKGKRAVPMRA L---EVPHQK-----G---KGMAG-GKFPKNAAEGIIDLLKQVRANAVVNQV-E-NPVIV I-AKADKASQPFRR------------NR-----RRAKR-CHVYIEV-------KDRTKLR ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------GKK-------- ------------------------------------------------------------ ---------------------MGKRIIQQA-------------RGKGSHTYRVRRKAFS- VKIGYP-A---------DLSGE--WECVKLIADGGHSCVIAKFKEVKGDKIFYNVAVNLL YEGQKIKLGG-------------H------EDGSISLIGDLKNGARIFNIENKPKDGGKF VRTGGNSAVVMVK-KG--N-DVVVRMPSKKEKKFDVHCRVTVGVAAGGGRLEKPILKAGK QYYIKKAKSKLWPRTSAVKMNAIDHPFG-GGRGKRI-----K----SKIAKRNAPPGRKV GLLRPRRTG-------KKK----------------------------------------- -----MKNKMEQKL------------EETKQGN----------------------RMREV KIEKVVLN--VGGTGDKLEKGVILLKTL-SGK-KPIKIKAV--K--RIPVWDVRPGLEVG TKVTLRGE-DA-EKFIKMVLPAINNTLKEKQIKDN-FVSFGIPEYIEIPDIEYIREVGIM GFEVTVVFSRA-GKRVEKKKVKKGKT-RRQVVTSKEIEDFMVTKFKIEI-LRRRRQVQ-- --- >GCA_016867655 ------M-SHGN--RKVRK-MRGSR--THGYGNTQKHR-GAGSRGGRGM-AGSKKHKWAY VSK-----YMPE--------------------------H-F--G-------RS-GFKRPQ CQVK--EK--KI-----A-NIGDLNL----NASKLLK-EGFL-KK---------EKDAYV VN--LTEKG--FDKLL----GAGKVSNKF-IITV---KECSGKAKEKIEAAGG--KLI-- LPEGKP----------------------A----EGQANETGETS---------EKV---- ---------------------------------------------------------MAM E--------------------KHFIQEGVIKSEI----------------ESFLKKEL-S RTGYSGINIQ------KTPTATRVVLYIEKPPLVIGKKGNRVNRLTKILTEKYGIENPTI DVQ-RVERPTLDPNIV----------ARRIAVALER--GVNRRRIAYKALRAIMLSGARG VEIVLSGK-IV----------GKG-------------GRSRVEKYS-------------- ----EGYMKKAGD-SLRLVDIGSTQANLKAGVIG-------------------------- ----------VTVKIV---------------QPGQ----------VFPDQI--------- ---------TVHEKTQMEG-----E-IQTEVKD-------NKPAKKRK-TKEESGA---- ------------------------------------------------------------ ---------KKKVP-----------HRGKTK----------------------------- -------------------------------------------------------AEKA- -EENA------------------------------------------------------- --------GTPTSEQSAPEQPSET------------------------------------ ----IENQSLEVQA---------------------------------------------- ------------------------------------------------------------ -----------------------------------------------MANVYSLDGKAEG KINLPTVFKT-EYRPDLIQRAVVSQQANRRQTYGTDPYAGLRTSADYYANRK---HTYRI TINRGMSRLPR-EKP-GGG-GLGKVRRVPHSVKGRSAHGPV------NKDFSKKINKKEY EKALKSAIAATAVKEIVEQRGHKLG--KI-AELPIVIDDKLESLKKTKDVYDAI---ANL GLEDELERG-AV-KAITAGKGKARGRKYKKRKSILIV-V-N-EDKG-------------- -----LKKAAENIPGVDAATVRELDVELLAPGTHAGRLTLWTKAA---VENVAK------ ------------------------------------------------------------ ---------------------------------------------MATGPT---YRVDYR RKRESKTNYKKRIETL-KSGLPRLVIRPSNKHVTVQLVRYHKDGDKVEVTSHSKDL-KKH GW----THNTGNVPASYLTGFICGLKGRQK-KIEEAIMDLGMNTSVKGSRIYAALKGALD GGIKVNH--DGAVLPS------EDRLKGTHIASYVK------------------------ KSKDIASDLAKIKEKVQNDY------GKQKS----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MARKELHYRGYTIE--------------------QLRAMPMDDLVKVY PSRSRRSLRRGF------TEMQKKLLASVKKNRSTV-DSGGRQ--ETIETH-CRDMP--- ------ILPEM----------------------------VGLVIGVYNG--------YDY I-----------PVEVKIEMLGEV----------------------------LGE----- ----------FSMTR-KPIKHGA------------------------------------- -------------PGVGA-TR-------------------------------SSLFVPIK ------------------------------------------------------------ ------------------------------------------------------------ ------------MEKARIILIGREIKKIHEVCSQIIDITKKIGSKFAGPISIPTRKMKIT TLKSPDGEGT-------STWERWEMRIHKRIIDL-EANERTLRQVMRIQVPDGVHIEIEL TK---------------------------------------------------------- -----------------------------LFN-APLHKKKAF-CRAMLSKELKKTY---- ---------------------GLN-SMQVRKGDTVKVMRG--ELK--GSTGNVIRVEVDK RKVYVDGLTMKKADGT-DIERP----------LEPSNLQITMLDLE-------------- ---------DKK-RK-----------------------------------KILERKAG-- -----V------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGIRPAKCYRWD--------------- -T-PAYTRVSSNP---GDSFITGI-PANKINLYDMGNL----TAEFDS-QLSIRPECDM- -QVRHNSMEAARIVVQKYL-EKDLGVS-NFHFKVNPYPHHVLRENVMAT-GAGADRVQQG MRQAFGKPVGRAARIKA-GQPLYTIYYN--ESPQATKLIKNVLRIPMKKL--PGPMKI-- ---------------------A-----FK------------------------------- ------------------------------------------------------------ -------------------------------MMQ-DLINDAITNIRNSVRVGKSECTVKP TSKLLVEILKVLQKEGYIDEFEHTDNGR-GGVIKIQL----------------------S KLINSCGVIKPHHPVKKDNYFKWEK--------------------RYLPAAGFGTLVVST PKGVMSHREAREKGHGGRLLAYIY-----------MAEKKS-------------KSGSKK KEGITL------------E--VQLPEGVQASIDNR-----KITVK--GPQGQLTKAMQ-- ----SRTVSAKM-EENK-IILT---AS-QNR---RKQRALINTEKGNVLNMIHGVKDK-V NYRLKICYSHFPMGVKLQ---GNI--LM-IDNFLGEKHPRKASIL--EGVKVDVKGQ--- ----DVVLSGLDKDKVAQTAANIEQTTRIKN---LDPRV----------FQDGIYIVEKD GKPVR------------------------------------------------------- ---------------------------MAKRHKPRAGSRAFAPRKRAKKQTPRIRHW-P- T--TG----ET-VCGFAGYKAGMTHVLAVDERKGRATS--GMEVFIPATVIEAPPVDVIA LRAYGKG--YKG-VE---TLIDIYCENPPAD-----L-----KKTL-------------- ----VLP---KKI------NTQEK-----------------------TKQLKEK------ ---IN--EISDIRLIVSTQP-----KLTSLPKKKPDIMEIGL-KGSVQ---EKLDYALSH IGK-KIPVKEVFKDNTFVDVTAVTKGKGFQGIIKRFGVRRQPR--KSTQKRRH--MGTG- GPIT-PSRKF-WFWPTPGQHGYHTRTEYNKAVLKVGA---DGK--EVTPPGDFLRYGPVK GDYLLLKGSVPGPAKRIIRLTVPRR---Q-K-EQS----SF-NVVHIDLSSKQGV----- ------------------------------------------------------------ -----MELKYAVK---------------------------------------PKDESKIA K----------------------------------------------------------- -----------AMVRDVD-MSPKHAMAIASKI--SGMKVDAAIKLLEKVRKLETPIPFKR HNT-GIGHRK-----GIQ---EKV-GRYPVKASGKIIELLKNLQANAEFKGL-DPEKLKL THIEAQKGVTRKGKKP-------K--GR--WKLWRTQF-VHVQAMA-------KET---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKTLLTQR-------------RGKGKPRFRSPSHRFK- GEIKYP----PL-AISRPVGGQ----VLEITHDPGRSSPIAKILLEDYSE-IQIIAPEGL QIGMWIQIGG-------------GKT---GDVGCIRAVGDLAEGTEVYNIEVSPGDGGKL ARSSGASASIVAH-DRKQG-LTQILMPSKKTILVNSRSRATIGRAAGGGRKEKPFVHAGQ MFYNRRIKGKLWPVVCGRAKNSLDHPHG-GGRHPHV---G-R----PTTVSRDTPPGRKV GHIAARRTG-------LRKK---------------------------------------- ----------------------------MEYSN----------------------VMQKP RIEKVTLNIGAGESGEKLVKAEKLLQKI-TNK-KTIRTFSK--H--KVPAWNLRKGEPIG CKVTLRGK-EA-EEILKRMLYAKDNKLTEDNFDKAGNMAFGIHEYIDIQGLKYDPDIGIL GLNVNTTLEKS-GYRTKRRRLNQRSPSKKHTITRQESIDFIKEKFGVEI-EAET------ --- >Bin307_genes ------M-PHKL--RKSRK-QRGSR--YCGWGQVGQHR-KGGMRGGKGK-AGGRKHFWIR TVK-----YEPE-------------------------RY------------KSVGFKPPS SLKP--RA--VT-----I-NIGDLEN---LARNKL-D-ME---VG---------GADALD LD--LEELG--YEKLL----GRGKIRVPL-AIKI---PEYSSRALEKIEAAGG--HIV-- --------------------------EIE------------------------------- ---------------------------------------------------------MSV V--------------------KRIIRDAIERVKV----------------DELLADEY-V QAGYGGITLT------KTPLGAQINLFAMRPGRVIGKRGRAIKEASERLERELGLTNPQI TVV-EVEFPELNPQIQ----------AASIANALQR--GIHYRRALFWSLNRTMEAGAIG CEILIKGP-L------------RS-------------NRGRYEKVV-------------- ----EGYVPKSGDPALRNVKKATMHVKMKKGAFG-------------------------- ----------INVSIV---------------PPDA----------KFPDKV--------- ------------------------N-LDGLPVIV-----YPEEEYELP-AGVEPDL---- ------------------------------------------------------------ ----------PETP---------------------------------------------- ----------------------VEPEASE---VVP------------EEKP-TEVTDAV- -DATS-------TDAPQSVADE-VQPVE-----------AEIVEIAPEE----------- ---------KPPLGSDVVEKAVEEEVVETATPDAPEP-------------VADE------ -PQLVEDEPDSVEAEI-------------------------KPE------------EEKP QAIEPEKTDE-----------APKAE------DLET------ESKTE------------- --TEGSPSDEEE----------------------------------MSVPVYNLESEQSD EVELPGVFST-PYRPDVIKKAVIFQQSNSFQPQGRDPMAGKRTTAESKGTGL-------- ----GIARVPR-LKG------SNRAAFGVSIVGGHQAFPPR-----SEKVIKKKINKKER RLAIRSGIAVTADRDIVAGRGHMIE--SV-GTLPLIVEDEVQGLTKTSDVKELF---IKL GIWPDVMRA-DR-KKIRAGRGKTRGRKRKVGKGPMLV-I-S-EDLG-------------- -----LVKAAGNLPGVDIVKVEDLNAELLAPGAHPGRLVVWSKTA---FTSIDK--FWGG NRT--------------------------------------------------------- -----------------------------------------??????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????MSKRMKRR-----------IGM-RRRQTTGLVTGSMIHCADNTGA RRLKLIQVVG--YKGRRRRLPNAGVGDLLIVSCREGTPEMRRQ---LFNAVIIRQRKPYP RRDGTWVQFDDNAAIILTPD--GEIRGSDIKGPVAKEAVE-RWPRLGSVARMVV------ ---------------------------------MS-FKQ-PAAE-----------C---- -D----DVDCPF------------------HGTLSVRGKTMDGVIVSDKMTKSVVVSIEY TRYFPKYERYARMNSRITAHNPPCID--AKTGDKVTIAECRPLSKTKSFVVVEK------ ----------EE---------------------------------------------E-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MPKDFVFRGLNEE--------------------QLKAVSMDEFIKML PSRMRRSLTRGL------PEEHRKLIEKIRSWQPGD---------KPMKTH-ARNMI--- ------ILPEM----------------------------IGKTVHVFSG--------RDF I-----------EVPIDLKKVGHY----------------------------LGE----- ----------YSITN-SPVRHGR------------------------------------- -------------PGIGA-SR-------------------------------SSMYIPLK ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------RERVMRSIMRIRVPNEVYIEMEI R----------------------------------------------------------- MVKR--------------GVTKPGKNRKRRFN-APNHVRRKF-LSAPLSPSLKIEY---- ---------------------GAR-SIPVRRDDTVTITKG--DRK--LTEGKVLRVDSER SKIYIEGVTRNRMDGS-MVQIP----------IRPENVMITRLELG-------------- ---------DDK-RR-----------------------------------AILARRGF-- -----GAKRRSA------------------------------------------------ ------------------------------------------------------------ ------------------------------------MKARNFREI--------------- -KGMAYTR---------RKYMRGI-PGSKIVKFTMGNP----NGEFSH-TVELVNLKEG- -QIRHNALESG------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????------------------------------------------------ ---------------------------MPRVRSPKRGSRSFSPRKRAKSIIGRIKYW-P- E-HEG----DPTLLGFAGYKAGMTHVFLIEDRDRAPDY--GKEMKNAVTIIDTPPMLVIG LRAYEKT--YDG-LM---ALTEAWMDIIPVD-----L-----YRRI-------------- ----KTH---GGA------SLASG-----------------------LKRIEKV------ ---KE--YIAELRVIVATQP-----RLASVEKKKPELMEIVIGGGSVD---DQIEYAKGL VGE-TLSVSDVFAAGESIDVIGVTKGKGFQGPVKRWGVRILQR--KSRKTVRG--VGSI- GPWK-PRRVM-PGVPRAGQMGFHNRTELNKRIVIMDS---DGD--KVNPKGGIHKYGLVR GDYIMLKGSVMGPQKRLIKLRKAAR-----K-SRYP-SEPP-QVTYINTEFLN-KVEAD- -------------------------------------------------------MFYLA YGAHMPSWKYSIQ---------------------------------------GLDPDRTA I----------------------------------------------------------- -----------ASGRDLR-VSHKAAREICHYV--KGMRLEKAKDVLQEVVALKRPVPYRR HNK-KVAHRK-----GVQ--GFDA-GRYPKKAAAAILKILDQVEANAEFKGL-YSDRLKI IHIASHKGRVIRNYIP-------RAFGR--SSPYFNYL-THVEVAV-------EEIQ--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKKLKVQR-------------RGRGGPTFRAKKTNKV- APIKYP-ALG-----SN-LNGV----VKDLYHEPGRGAPLVYIKLEDGGG-FYIAAPEGV YIDQEVSIGE-------------GAP---ARIGNVLPIGSIPESTMVCNVELRPGDGGRL ARSGGSFATVVSH-ID--G-KTTLRLPSKRSIEVKDACRATIGIVSAGGRREKPFMKAGE MFYRKKAKGQVYPEVKGIKMTAASHPHG-GGRHRRP---G-S----STTVSRHAPPGAKV GLIAARNSG-------RRLRRKRL-------------------------??????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??? >GCA_007116645 -----MT-VTKK--KKVRD-YRGSK--THGGGAMKKRR-GAGSRGGRGR-AGSGKRSDSQ K---------PSYW-----------------KD-----WEM--G-------KH-GFTS-- HSRN--VV--VA-----T-NVSDLHR----EIARLVE-QGKA-TQ---------KGSAFT ID--LSDIG--VDKLL----GSGKITSAV-HVTV---KSASARAIEKVEAAGG--SV--- -----------------------------SVSEEALED---------------------- ---------------------------------------------------------MAI E--------------------RKFVDQNMREFRI----------------KRFVEENV-Q RVGLSDVKLK------KTPLGDKIVIHASRPGLVVGRGGASIQLLTRQLKEEFNLDNPQI EIE-EIEKPDLDADIV----------AERVLNTLERFGSGRTKSIGHRAMADTIRAGALG VEIIISGK-I------------PS-------------MRAKSWRFY-------------- ----QGYLKKAGDIAVIGVDKSIKSVTLKSGAVG-------------------------- ----------IRVSIM---------------PPGL----------VLPDNI--------- ------------------------T-L------------T-EQLVTE--VE--EVT---- --------------------------GQPEA----------------------------- --------LETE--AI---------ADAKPAK---------------------------- ------------------------------------------------------------ --AEP------------------------------------------------------- ------------KADKAKPKANEK------------------------------------ ---NVSEEQSSETE---------------------------------------------- ------------------------------------------D-KQ-------------- ----------------------------------------------MKLAIYNTKNSQNG DIAFP--ISE-PLRTDLIRRAIQAIRSRARQAYGADPRAGLKHSTNLRKRRR-V---YRG SYGIGIARTPRKILSRNGRRLNWVGAEAPNTVGGRRAHPAK-----ASKIWERKINKKEN RKAINSAITAALDKEVVTTRGHIIP--K---NYPFALDADFDALNKTKDVIAAL---QTL GFSEDLVRGEN--GAKS-----------------LLI-V-T-ESES-------------- -----LTKAAKNIPGVDVASARQLNAYVLAPGAHPGRATLFTAQS---IKVLSGEE-APA TKVATKATPK--------------KAAVSKPKAVKAEAKK-------------------- ---------------------------------------------MAKNNR---FNLPFR RRRQLKTDYKKRLTLL-KSREPRLVVRKSNANTVVQIIEYRPDGDVILAQGSTAQL-ADL GW----KASAGNVPAAYLAGYLAGIRAKQA-GVTNVIADLGMQKPFHGGRLFAAIKGAID AGLTVPA--SESAFPA------EDRLTGAHID---------------------------- --DSLPKLVEAVKKK-------------VGA----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKPI-TSSVTEAFQPGSKVATCDNSGA KIVEIISVLN--KKTSKGRRSGAGVGDMCIVTVKKGRPDVRKQ---VMHAVIVRQKKEFR RVDGVHVKFEDNAVVVCKDEK-GNPKGTIFKGPIAKEAAD-RWPGVANVASIIV------ -----------------------MAAKKT---------A-KTVA-----------P---- -E----GADELS------------------ASPISLRGQEFVGTVVSAKAHRTVSVSWER RRHVPKYERYERRRSKVAAHNPDEIG--AKEGDVVRIKESRPLSKTKHFVVTEI------ ----------IT---------------------------------------------RKE A----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKVFTYRGKTLE--------------------ELQQLTRDELAALF DSRARRTMMRGY------PEEWKKAEAKILAKDK-------------VKTH-ARELI--- ------ILPRM----------------------------VGKTVLVHNG--------KEF R-----------EVRIQEEMIGQR----------------------------LGE----- ----------FALTR-NNVRHSN------------------------------------- -------------PGVGA-TR-------------------------------SSSAASVR ------------------------------------------------------------ ----------------------------------------------------???????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- -MKQ--TFKRT-----WNKSVQARKQRKYRHN-APLHTQSKF-LHAALSKDLRAKH---- ---------------------SRR-NLRVRKGDEVEVLRG--TFK--GEAGAVEEVDTTK QRVVIRGVASVKLDGS-RKSYP----------VAISNIRITKL-VD-------------- ---------DKR-RI--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MARDRKFVAYRRL--------------- -E-RPYTRKSKYR---RYQYVRGT-PHSKIVRFVMGSR----TKTFPL-SVKLVSKTDL- -QIRHSSLEASRMSANRRL-EKAAGKQ-GYYFRIHKYPHHILRENPLAS-GAGADRLSTG MKKSFGKAVGVAAQVRR-GDVVIEIGC---E-PKHLDVAKKALNIVCSKL--PNSYYI-- ---------------------V-----VDKVPTGSNEVS--------------KTHKRLP KVYE-------------------------------------------------------- -----------------------------M-ALN-NPLANVLSAINNNERVSHRELTLHN NSKVIRRVLDILKDQGYVSSFEIVEDGR-GGTLKISL----------------------A GTINKIGVISPNFPVGKDDFQRFEQ--------------------RYLPARDFGIIVVST SKGMMTHSQAKELGIGGRLIAYCY------------------------------------ -MKATI------------EEQVEVPQGVTASYENS-----ILSVQ--GKAGQAQRKLV-Q P-G----IEVSV-KDGA-IHLV---AA-VAT---QREKRHIYTMRSHVRNLLRGAEEG-H TYKLKVCSGHFPMNVSIS---GEK--LT-VKNFLGEAVPRVLQLK--KGATVKLDGD--- ----IITVTATSKELAGQQAADIEQLTRITN---RDRRI----------FQDGVYIIEKD GRPLL------------------------------------------------------- ------------------MG--------KKINHSRHGSLQYWPRKRAARQHARVRSY--- --TSDN---E-GLAAFAGFKAGMTHIQVVDNQKNSPTK--GREINVPVTIIECPPLRIIG VRLYKKN-----------------VKGYGET-----A-----ATEV-------------- ----RLKSSSKHLERTTSWQPTGS-----------------------LDKLN-------- ---AE--DYTRATLIVHTQP-----DLAGFGQKKPQIFEAGFNGS-VA---DTIAFAKE- -SE-EITVDKILQAGSFVDAHAVTTGKGFAGVVKRFGVSLRSH--KSEKSNRK---AVI- GPEG-YGKVQ-YTAPQAGRMGYHLRTEYNKQIMAIVAP------EEVQIKGGIVNFGQVK NTTLLVKGSIPGPKKRMITLVKATR-----QDPKAS-TQAM-EVTHIATRSQQGNN---- ------------------------------------------------------------ -----MGYKYAYQ----------------------------------------GDQKTTA R----------------------------------------------------------- -----------AAGTDIP-VSTKSTIMVANFI--RGKSVTRAQRDLGEVLKKKMAVPFTR FTD-GAGHKP-----G-----IGP-GKYPIKATTHVLSVINAAAANARDRGF-G-DDLTI VSVTVHQAARQMRY------------GR--LRGRQRKG-THIEVVV-------AESEEKT ----TRKTPQKVAK------KA-------------------EVKPAKAEAKSKAAE---- -------------KTEAKPK-----P-------KTEAKPK----------AEAA------ ----K-----PKA-------------------APKKAEASE--------PKA-----SKE ------------------KKE--------------------------------------- ---------------------MGKPIIAQK-------------RGKGSPTYTVTSHRFK- GQAKH-----FADG-----EGQ----VVDIVHCAGHSAPLALVEHEQGLL-YLTIAGEGA QVGEIVQIGE-------------NAE---LKVGNTLMLQDVPEGTPVFNIEGQPGDGGKF VRSSGSAARVVTK-TA--T-HVTVALPSKKQRTFSAKCRATIGVPAGGGRVDKPLLKAGA AFHKYGARNKYWPKVSGNSMSAYDHPFG-NTRSMRK---S-K----SKPAPRDAPPGRKV GMIRPRQTG-------RK------------------------------------------ -------------------------------MN----------------------VMKAL QIDKVTINFGAGKDQQRLEKGMQLIKMI-TGK-NPVKTITQ--A--RIPGWGLRPGLPVG LKLTLRGK-EA-QDVVKRLLEARENRLKPSCVDNNGNISFGLSEYIDIPGVRYDPKIGVI GLQASITLTRP-GYRVMRRKLKATSIGKGHRVNKEEATEFMKEHFGVEF-VQ-------- --- >GCA_003560545 ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MK---------DNDHFK VD--LEGMG--YTKLL----GTGIIKQKL-DITV---KHASGKAKEKIEAAKG--KV--- -----------------------------NLLSE-------------------------- ----------------------------------------------------------MI E--------------------RKFVAQNIRELEI----------------KEYLYKEL-G KVGLSNVKVQ------KTPLGEKILVSASRPGLVVGKGGANIARLTKELKEKFNLENPQI EID-EVTDPRGSAAIT----------AEVIANSLERYGPVRFKGIGHKALSTIMDSGAHG AEILISGK-I------------PS-------------ARAKTWRFY-------------- ----QGYLKKCGDISISGTDKSIQVARLKSGVVG-------------------------- ----------IQVNVM---------------PGST----------KLPDKV--------- ------------------------I-P------------K-------------------- ----------------------------TE------------------------------ ----------EQAK-----------EEA---E---------------------------- ---------------------------QKAKE---------------------EEKQE-- ------------------------------------------------------------ -------------EKKAAKKKTTK------------------------------------ -----KKAAKK------KSVKKK------------------------------------- --------------------------------AAKK------AAKKK------------- TAEEK-----------------------------------------MKLKLLGKDAKETG NIDLPLQFKE-PLRKDIIKRAVIALQLNNRQPYGASPEAGKRASTYLSKRRR-A---YRG TYGIGQSRTPRKILSRRGTQIYYVGAFAPHTTGGRRAHPPK-----ASKSWEKKVNEKEN RKAIRSALAATVNAELVKKRGHKAP--K---EYPFIITDEFEKITKTKDLVKAL---EAI GFKEELERGNT--TKIRAGKGKTRGRKHKTKKTMLFV-V-S-QECD-------------- -----LEKAARNLPGADIAVINNVNAELLAPGAELGRLTLYTESA---IKKLGEENLFTN TNKKKVVKKEKKKQA--------------EEKPAKK--KTTKKKAAKK------------ KTVKKTVKKETEKAKAE----------------------------MKQKTT---YTVRHR RRREGRTDYKKRLELL-KGRKDRLAIRKTNKHIIIQVIKYAPEGDKVLLTANSKEL-EKK GW----KHSLKNIPAAYLTGLLAGVKAKEK-KINGAVLDIGLYSPLKGSRIYAALKGVID SGLKIPA--GKEIFPG------EERLKGEHISKYLE------------------------ KHKTITQDYEKIKSEL------------LK------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKSI-SASIPKCLPHGALVDTCDNSGA KVLRIFGVKG--HKTVKGRMPSARIGDMVKASVVKGRPDMRKT---VVLAVIVRQKKEYT RPDGTRVKFEDNSAVVVKDDK-GNPKGTILKGPVAKEACE-RWSGIAKISSMIV------ -----------------------MAEKQ-------------------------------- ---------------------------------IGTRGRKLTGKVTSDKMSKTVTVSWER RKYNSKYERYEKARSKVKAHNPEDIG--AETGDLVEIAETRPISKTKNFIVTKI------ ----------VK---------------------------------------------KKT E----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKVFTYKGKTLE--------------------ELQKLSMKELSALM PSRQRRKIHRGL------KEEEKALVEKIKKKNS-------------VKTH-LRDMI--- ------VLPSM----------------------------VGKVVRIHNG--------KTY Q-----------AITIPQEAIGCY----------------------------LGE----- ----------LVLTR-NRVMHTS------------------------------------- -------------PGVGA-TK-------------------------------SKSNVSVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQRARVKLASTDINKINATCDYIRDIAEKTGVVLRGPIPLPTKKLRIT TRKSPCGDGT-------ATWDRFEMRVHKRLIDV-GLDERALRLIMRVPIPEGLNIEIEM IDA--------------------------------------------------------- -MKT--AFSKT-----WKSSTQPRKQRKYAYN-APMHTKSKF-LNANLSKTLRERH---- ---------------------GKR-SVRLRTGDKVRILRG--NNK--GKEGRVETIKVKD TKVYVTGIEKPKKDGS-KIKVA----------LKPSNLQIVELKLD-------------- ---------DKK-RKQ----------------------------------KLQVKETK-- ------------------------------------------------------------ --------EDKKNG---------------------------------------------- --------------------------------MAKLMRAVAWRRL--------------- -E-RPYTRRSKYR---EKSYVRTV-PNNRIVRYIMGNQ----KKEYAY-RVLLNSKADI- -QIRHNALESARLTANRLL-EAK-APS-DYQFKLRVYPHHILRNNPLAA-GAGADRMSTG MSHSFGKPVGIAAQVRK-GQPVLEVNV---N-KERLKLAKQALDRARKKM--PCGFSI-- ---------------------T-----IEEVKPKAQAAN--------------------- ------------------------------------------------------------ -----------------------------M-SLN-DPLANVLSHVYNYEKLGKKELVTDN NSKVIKEVLRIMQEEGFIGSYEEIDHGKGGKALKIHL----------------------I GSLNKCGAVKPRFRVKVSDYEKFEK--------------------RYLPAMDFGVLIVST SKGIKTNTQAKKENIGGTLISYAY------------------------------------ ---MGL------------TEKIEAPENCTVVQEKN-----FVVAK--GPKGELKRKLT-D K-K----VQVKQ-EGQE-VTLT---YP-EDT---KRAKRLMNTNRAHIKNILKGVNEG-F TYKLKICSGHFPMTVNVK---NDV--LE-VKNFIGEKVPRTLKIH--PDAKVNVSGE--- ----EIVVEATNKEVAGQVAASIEKLTFRPG---FDKRI----------FQDGIYIIEKA GKKLVH------------------------------------------------------ ---------------------------MPKKGRPRFGSMGVWPRKRAKRPYARIRSK-P- S-SK-----EAKPLAFPAYKAGMTHIIVRSKDNTPKKA--DINVSMPVTILECPPIRIAG VRLYKKK--GTG-IV---VDKQLNFKT-EKH-----L-----ARKT-------------- ----LQS---KDK-----EK-QAK-----------------------PEDLDKLN----- ---PD--DYEDITIQIYTNP-----KLIDL-KKTPELFEVSLGGSN-K---EKIEYIKNH HDK-NILVTDLFKEGQVVDTHAITKGYGTQGPVRRFGIGLKNH--KSEKGRRR--PGTL- GGWIAQAHYM-YRVAYAGQTGYHQRTQYNNPLIKISD---KPE--EVNPKGGFVRYGTVK TSYVMVKGSIQGPKKRLVTLTQPIRPPEK-Q-KKV--FTSD-SIRYISKESKQGK----- ------------------------------------------------------------ -----MAKQYAFQ---------------------------------------GF-KENMA R----------------------------------------------------------- -----------ATGLDLG-ISTKISIEIANHL--KGKTTEDAKKILNKVLRKEQPIPFKR FTD-GVGHRK-----I----ISGP-GRYPEKASKEFLKLIEQAEANAQVKGL-AS-QLKI IHLNANKGSDQIRP------------GR--QRRRMFKR-THLEIVV-------EEQE--- -----EPKKSRKKEATPSKE-----------------------KAEEKKEEPKTEKQ--- --------AVTETKKEAEKKEEGKK---------TEEK------PVK---KKE------- ---------TPKEEKKA----------------EEKEKAKPA------TEKPS-PKKQAQ ------------------EKKQAEE------------------------------QK--- ---------------------MGKNLIQQR-------------RGRGTQRFRAPDFRYK- GDIKM-----LRKE-----SYT----VKNLVRCPGHTAPLIEAEYNDKTK-SLLVAPEGV AVGETYNIG--------------GSE---VRAGNILSLKDIPEGTSIFCIEAKPGDGGKF VRSSGGSAKLVGK-TG--K-AVKVLLPSKKEKEFHPECKAMIGVIAGSGRTDKPLLKAGK KHHLMKARNKFYPIVSGTAMNAVAHPFG-NKRTLRK---S-K----NKPVSRHAPPGRKV GSIAARRTG-------RKKGK--------------------------------------- -------------------------------M-----------------------KMKEI KVAKVTLNIGAGKDQRLLEKGVKLLKNL-TGT-EPVKTVTQ--K--RIQGWGLRPGLPIG VKKTLRGK-QA-DEMIKRVLYAKDNLLEESYFDNHGNISFGLPEYVDIKDAKYDTEIGMM GLQVSITLTRP-GYRVKHRSVRKKNIPAKHQVKKEEAMNFMKEKYSAKI--GEE------ --- >GCA_007117735 -----MT-VNHR--KKNSR-HRGSW--THGWGEKKKHR-GAGHRGGRGN-AGSGKRGDAK K---------PSYWKI---------------KK-----F-S--G-------KH-GFTN-- PTPR--SV--HT-----M-SLEQLNV----AITRLVQ-SGHA-VQ---------EKDLFK VN--LSALG--VDKLL----GTGKPVHAY-EIVV---NAASDGARRKVEEANG--SV--- -----------------------------LLGQSEE------------------------ ----------------------------------------------------------MI E--------------------RKFVAQNFKEFRI----------------KEYIKESL-S RVGLSDVKLQ------RTSVGDRIVVVASRPGLVVGRGGSTIQKLTADLKAQFDLENPQI EIE-EIKDYNSDARVV----------AESIVNQLDRFGTQRFKGIGHKSIEGIMRSGALG VEILISGK-I------------PS-------------SRAKTWRFA-------------- ----DGYMKKCGDLAITGVDTAKDFVTLKTGVVG-------------------------- ----------IQVRIM---------------PAST----------KLPDQI--------- ------------------------S-F------------DKREREAA--AV--EVSEV-- ---------------------------KDES----------------------------- --------LEAEVKERE--------EKASKKK---------------------------- ---------------------------TSSKK---------------------------- ------------------------------------------------------------ -----------SSSKKTSKKTSTK------------------------------------ -----KSESKKSSEEKPSEK---------------------------------------- ------------------------------------------EEKSQ------------- KDGEEQ----------------------------------------MKLKVVDQKNSETK TITLPDQFSE-PVRKDLIKRAVLALQAARRQRYGASPEAGKQYSAYLSKRRR-A---YRG TYGIGQSRTPRKVLNRRGTRFYFVGAFAPQTVGGRRAHPPK-----AEKSWDQKINVKEK RKAIRSALAATMSADLVAQRGHKVP--K---GFPFILDTTFEDIAKTKDVVLAL---KTL GFEDELVRAST--TTIRAGVGKRRGRKTITKKSFLFV-V-S-KDCP-------------- -----LLKAAANIQGADVIPVTSLNAELLAPGTHEGRLTLFTDGA---LDVLSQRKLFTE GGAQ-------------------------------------------------------- ---------------------------------------------MARNAI---YTVQYR RKREGKTNYKKRLELL-KSGQNRLVIRRSNTSITIQFVQYVPDGDKVLMTFNSNQL-ESF GW----KYSKKSLPAAYLAGLAAGKQMIDA-GHTQAILDLGLQTPLKGSKLYSALKGVID AGVSIPS--SDHVFPS------EERLTGQHIAQYSDLASSAS--AYKKA---------GL NPADIPKAVQAVKEKI------------QN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAI-KGKVSDGLQVGSVISTCDNSGA KLIKITGVKR--KKTVKGRIPGAGVGDMVVAAVKKGRPDMRKK---VVYAVIVRQRKEYR RPDGTRVSFEDNAAVVLKDEK-GNPKGTIFKGPVAKEVAT-RWPAVIKVANMVV------ ------------------------------------------------------------ ------------------------------MENISIRGKTFTGKVVSAKMNKTVVVQWER RVLIPKFQRYAKRRSKVSAHNPESID--AKEGDIVKIQETRPLSKTKNFIVIEV------ ----------VN---------------------------------------------KEQ ENESN------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MALKEFKFNSKTLD--------------------ELKQLSLSELAEIF PARQRRTIKRGF------SDTHKKLIEKINKKNN-------------VKTH-LRDMI--- ------VLPSM----------------------------VGKTVQIHTG--------KGF Q-----------AILLKEEMIGHY----------------------------FGE----- ----------YALTR-RKATHTS------------------------------------- ---------------VGV-TN-------------------------------KPKR---- ------------------------------------------------------------ ----------------------------------------------------???????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- -MKS--IFSLH-----WLKSIQPRKQRKYRFN-APLHRKGSF-LNAPLSKDLQQKH---- ---------------------NVK-TLRVRSGDRVKIQRG--QFK--SLEGEVSRVDVAR EKVYVSGAELAKKDGG-KVSYP----------IHASNVLIVSLK-D-------------- ---------DKR-R--------------------------------------MKKVNK-- ------------------------------------------------------------ ------------------------------------------------------------ ----------------???????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????----------------- -----------------------------M-ANN-DNLAMVLSQMDNAIKVGKSSVTTSI SSNLIKEVLTLMKNEGYLAEWVEHEDSK-GNYLTITF----------------------N GKLNKCGVIKPRFAVGVDNFEQYEK--------------------RYLPALGFGLLFIST NKGLLSQVQAKEENVGGRLISYCY------------------------------------ MIQENI------------SQSVTLPEGVSAAVSDG-----VLTVT--GSKGSVSRNFL-H P-K----ITVHS-KDNE-VEFL---AK-KFT---RNEKKVMNTYVAHVKNMCKGVTEG-H EYTLKICSGHFPMNVSVK---GSS--FE-VKNFIGEAVPRVLELK--EGADVKVNGD--- ----TITVTGIDKERVAQTAASIEKLTRRNG---FDRRI----------FQDGIYITNKD GKAIQ------------------------------------------------------- ---------------------------MAKRKNPRHGSMQFWPRVRASRQYARVRNT-P- I-LK-----ESKLLGFAGYKAGMTHVVATDTSKTSPTK--GEKISIPVTVVECPPLKVSA VRFYASK--GYG-SV---VEQEVFLKT-GKE-----F-----ARKA-------------- -----VP---K--------AAVGS-----------------------VDDIEKVP----- ---LD--NITHITVQVYTQP-----HHAGVGKKTPEVFELPLSGSV-Q---EQAQLAKTL AQK-EISVQDIIQPGDMLDSRAVTKGKGNQGPVKRFGVNLRSH--KSEKTIRG--PGSL- GGWIAQGHSM-YRVAFSGQMGYHQRTQYNNQVLAIV----QPE--EVNPAGGFITYGEVK QPCLLVRGSLQGAKKRLITFTAPFR-AHA-K-KSLP------AVEFISKDSKQGN----- ------------------------------------------------------------ ----MTKTNYAFQ---------------------------------------KFGSDC-A K----------------------------------------------------------- -----------AYGRDLG-ISTKASINVCKAL--RGLSVEKAVAYLDNVIALKVPIAYTR FTD-GVGHRK-----G----NFAA-GRFPVKAAKAIKEIILSASANAAHQGL-G-DDLKI VHLCAHKASTPFHQ------------GR--QRRRAMKR-THIEVVV-------QE----- ------------------------------------------------------------ --------------QEVKKGVAQ------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKPITTQK-------------RGKGSQTFRSPSFKFK- GEAKI-----LPHKE----NAL----VMDLVHCRGHSAPLAQLYYDDGEI-GYSIASEGL MVGDQVFFGD-------------EAE---LKNGNVLPLKSIPEGVIVCNIELRPNDGGKL VRSSGASARVVSK-AK--D-GVVLQLPSKKQKKFHPNCKAMIGVVAGGGRVDKPFLKAGN KFYAAKARNKYWPVVSASAMNAVAHPFG-NKRTLRK---S-K----AKPAPKNAPPGRKV GAVRARKTG-------RGR----------------------------------------- -------------------------------MN----------------------VMKEI KIEKLTLNIGAGRDDRVLKKAIKLLEHI-TGV-PPVQTTTK--K--RLAAWGLRPGLPIG AKITLRGD-QV-YKLTERLLAAKEKKIKQSWFDNHGNISFGIHEYVDIPEVKYDTEIGIL GLQVSLTLARP-GFRVKKRKLHKASVGKSHMIDKKEAIDFMTERFGVAL--EE------- --- >GCA_018262275 -----MP-VNKR--SK----YRGSR--TCGGGTHKNRR-GGGSRGGRGH-AGGCKHHFVR YYM-----QGK---------------------------T-Y--G-------KN-GF--HN PTPT--DV--EA-----M-DLGTLDL----MVDSLLS-QGIA-KK---------EGKAIA LD--AGAIG--IDKIL----GQGRVTRAL-NIQA---RAFSEAAKRKIEEQGG--QAL-- VA---------------------------------------------------------- ---------------------------------------------------------MAV E--------------------RKFIAEGIRRARV----------------EKYLTKEL-R RAGFGGMDIA------RTPLGTQVTIFAEKPGIVIGKGGKVIRQLTQDLATGYGVESPQV DVQ-QVGNPNFNAQIM----------AERLANAIER--GWYFRKAGQSIITRVMESGALG CEVIIAGK-L------------TG-------------PRARVQKFI-------------- ----RGYIKHAGEPSRTIVERGYAVAIKKLGVIG-------------------------- ----------VQVRIV---------------PPDA----------KLPDDF--------- ------------------------R-L-------------VEEPPIKE-APPQLVV---- ------------------------------------------------------------ ----------TEIG-----------EDVDAE---LA------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AEVEPIPDIVEEET---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------RSLLIV-T-A-GEP--------------- ------LRAARNLAGVDAVSVRELNTEHLAPGTHAGRLTVWTEAA---VKALGELP---- ------------------------------------------------------------ ---------------------------------------------MAIGPR---YFLPFR RRREGRTDYYARMKLL-LSQEPRMVVRRTHRQIIVQMAVPEPQGDRTLVSASSFDL-APY GY----TGSTSSTPAAYLTGMLFAVRAKKA-GYGSAVLDIGLNRASPGARVFAALKGAVK AGLQVPH--GEKVLPA------DARVRGEHIAAYAPQ----------------------- RAGDLATQVDQVAAAI------------LKEMK--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAK-QSYIPRALNTGSRLACADNTGA RVVQIISADG--YHGVRRRQPKLGLGDLATVSVKKGTPEMRKK---MEKAVVIRQKKEFR RPDGLRVTFEDNAMVIVNET--NEPKGTEIKGPVAREVAE-RFPKIGSMATIIV------ ------------------------MAKNLG---LD-VTP-PQQE-----------C---- -G----DINCPF------------------HGSLPVRGQVITGKVVSDRMKGTVVVAREY LQYIRKYNRYEKRTSKIHAHNPPCLG--AREGDEVTIAECRPLSKTKAYVVVEV------ ----------TR---------------------------------------------P-- ------------------------------------------------------------ ------------------MVKKTQK----------------------------------- ------------------------------------------------------------ ---------RMPRRREEFTYHGHTIE--------------------ELKTMPSSELIPLM PARVRRKFRRGL------SRDEEDLLSRVRGGDPK------------IRTH-LRSMV--- ------VMPEM----------------------------VGKSLEIHNG--------KEF Q-----------KVDIQPEAVFHY----------------------------LGE----- ----------FALTR-RKVAHGA------------------------------------- -------------AGIGA-TR-------------------------------SSKYVPLK ------------------------------------------------------------ ----------------------------------------------------???????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- ---------MA-----VTKSIQPRKQRKARYT-APLHVQGHY-LSAPLSQELREQY---- ---------------------KRR-SLRVVKGDTVKVLRG--DAK--GEEGIVDEVDVGR CTLTVHGVTLTKADNT-EVPRP----------VHPSNVRITKLNLK-------------- ---------DPR-RA-----------------------------------ERLGEVE--- ------------------------------------------------------------ ------------------------------------------------------------ ----------------???????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????----------------- -----------------------------M-TRT-NPIADAMTAMKNAADTGKPDCIVEP ASKLLGAMLRVMQEYNYVAGFEFIDDRR-GGQFRVQL----------------------N GNINKCGAINPRFNVKVDEMEQWET--------------------RFLPAKNFGILLLST SRGVMSHDSARKAGIGGELLGYVY------------------------------------ ---MAI------------TRIVKIPEGVTLTLEGS-----TLSVK--GPKGNLSRNLH-F P-G----IRMTV-AGSE-LAIT---TE-SER---KKLLAMVGTYAAHVRNMCRGVTDG-Y QYRMKVVYSHFPIQLKMA---GST--LE-VHNFLGEKTTRYARVE--PGVKVALGSD--- ----EVTITGIDRETVGKTAANIEHATKIRD---RDPRV----------FQDGVYIVERA ------------???????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????--------- -----------MQ----------------------------------------VQGEEFA R----------------------------------------------------------- -----------AKAHEVD-ISPKHAIEIARFI--RRMNADDAIEYLERVVALEKAIPFRR FNK-KVAHKR-----GLV--KAAS-GRYPEKAARAYLKVLASVKKNAEYTGL-DAANLKI IHVSANRGRGFDSFMP-------RAMGR--ATPKRRER-VNIEIIV-------KEVE--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MEGT GVGETLSWGK-------------GAD---VKNGNTLPLREIPVGIMVCNLENRPSDGGKL VRAGGGQALVMGK-SEE-D-RVGVRMPSGKLKWFHGDCMATVGIVAGGGRGEKPFVKAGK KFHKMKSSASKWPIVRGVAMNVIDHPFG-GGAHQHA---G-R----PKTVSRGTSPGRKV GLIAARRTG-------RLKK---------------------------------------- --------------------------------------------------------MQKL HIGKVMVHMGVGESGEKLVKAEDVMKQI-TTQ-TPIRAIAR--T--TQPAFSVRKGAPIG CKVTLRGD-TA-ASFIETALSVIDRKLYRTQIDRQGNFSFGIEEHTDFPGMAYDPAIGIF GMDVNVVLEKP-GVRVARRKVMPRRLPRKQRVTPDEAIAFLQEAYKVEV-Q--------- --- >GCA_013375455 ------M-PHSK--RDIRK-YRGSR--THGYGRVGQHR-KGGQRGGKGK-AGLHKGGWTW TVK-----FDRY--------------------------H-F--G-------KY-GFKRPP RIIS--HA--RI-----I-NLGQLEI----VIDKLLA-QKIA-KQ---------DGNKIS VN--LLELG--ITKVL----GSGKISRPL-IITA---PSFSKIAIKKIEDAGG--SAL-- GPNT-------------------------------------------------------- ---------------------------------------------------------MPA I--------------------EHFITKKIKKTEV----------------DEFFAQEL-K RAGYGGVDIL------KTPLGTRVIIHAARPGIVIGRRGRNVQELTVTLEEKFNIENPQI EVS-EIEVPELNAMVM----------AERLASRLER--GTHYRRAAYSILRRIAAAGAKG VEITISGK-L------------TS-------------HRARYKKFR-------------- ----EGFVAKCGEPAFLYVDKAVAHAILKKGIIG-------------------------- ----------VSIYIMQ--------------PTDR-----------LPNEI--------- ------------------------D-I--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------I---- ------------ITPEELEAQSET------------------------------------ ----FKGE---------------------------------------------------- ------------------------------------------------------------ --------------------------------------------MVQQVNVFSLDGKAVK TIPLPEVFQT-PFRPDIINRAVLAIQTHRFQPKGTNKKAGQRNTAESVGPGR-------- ----GISRVPR-IKG-GGTPAAHQGGFAPGMRGGRQAHPPK-----PEKNIRKEINKKEN TFAIRSAIAATVNKGKVSERGHVID--EL-VEIPTVLVDDFEKLQKTSEVREAL---KNI GAWGDIERA-SV-KKIRPGKGKMRGRKYKKRKSVLIV-V-N-KNNG-------------- -----IYQAARNITGIDICEVKNLNAELLAPGGHCGRLTIWSESA---MNQLET--LFA- ------------------------------------------------------------ ---------------------------------------------MARGPR---YHVKFR RRRNGKTNFYYRKRLI-LSNELRFIIRPSLKHIKIQIAKAELLGDKIISSSSSMELVKNF NW----KGATGNLPAAYLTGLLAGKKALKN-DIKNGNLDLGIASPIRGNRHFAALKGLID AGIEIPH--NDKIYPP------VNRIRGDNIANYAKTLTETESPEPGQQFNLYKK--RGL NPQKLPAHFDEVKEAI------------IKQYK--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------MGKRRIR-----KK---GAHL-LPKISRGIPTNCKLICSDNSGG KILKVIAVIG--YKGRLNRIPNAGVGSMVVVSVVKGTPEMRRQ---IVRAIIIRQHKPYR RADGRWIQFEDNAAVITSPL--GDPKGSEIRGAVAKEAAE-RWPRLASVASMVV------ ------------------------MVRDIG---FE-VEA-PRKE-----------C---- -D----DPHCPF------------------HGTLPLRGRIFNGIVIRQRMSDACVVRRDF LRYIPKYNRYERQHSNINCHVSPCIE--ISAGDAVKIAECRPISKTISFAVVEL------ ----------IE--------------------------------------------SE-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MVKKFAFRGYSLE--------------------ELQNLPMDEFIKLL PSRQRRSMLRGL------PHRQKKLLENLRRARRAL-KKGKKV--V-VRTH-ARDMV--- ------ITPEM----------------------------VGLTIATHNG--------REF I-----------SVEITPEHIGHY----------------------------LGE----- ----------FAPTH-KRVSHGN------------------------------------- -------------PGIGA-TR-------------------------------SSQYIPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------VQKARIRLASTNSKKLKEICDQVKRIVERTGVHISGPIPLPTKKLRVP VRKSPCGEGT-------ATWDRWEMRIHKRLIDI-DADERTMRQVMRIRVPDDVYIEIEL K---------MKK---------------------------------------------NL GLKM--Q-ADK-----KSKTKSRRKQRKRFYN-QPHHKRNKL-FTAKLHDDLLEDH---- ---------------------DIK-RLPIRKDDTVLVVRG--EFR--DMEGKVSRIDRQK AQLFIDGASIEKSSGT-TFDIP----------IHPSNVVLTKIEVK-------------- ---------KDKWRK-----------------------------------KIIDRKVKIT ------------------------------------------------------------ --------EEF------------------------------------------------- --------------------------------MP-KRPWSSYHNI--------------- -KGKPYVKRWKKTKKGRREYVHGV-PDSKIRIFTMGT-----NKDYDY-HVFLISDSNA- -QISHLALEAARVAANRHL-RNEVGIE-NYFLRILVYPHHVVREHRMMA-FAGADRLQDG MRKAFGKPFATAARVRR-DQKLMSVKV---D-KKDLPFAKHAFQVAKMKF--PPHCHL-- ---------------------E-----TIKLRE--------------------EETTTPE ------------------------------------------------------------ -------------------------------MLM-DPLANCLSNIINHERIGKIEVIVEP ASKIIAETLRIMQKAGYIGEFELIDDGR-AGKFLIQL----------------------L GRINSTGVIKPRYPVNYTSFEKWEK--------------------QFLPARNFGLLIVST AKGMMSHKEAIDLSIGGRLIAYVY------------------------------------ MSDFGLV-----------ETTVEIPTNINIDVKDR-----VVTVS--GPNGTLMRDFK-F A-R---SITIER-QEDK-ISIF---TY-YPR---KKEKSLLNTISSHITNLVRGAKNN-F IYKMKVVYAHFPITVKVS---GKK--VN-IENFLGERSPRTAKILG-EKTKVTVDGD--- ----DVIIESPYIEDAGQTTANIQLATKIKN---KDPRV----------FQDGIYLYYKG LGEMDLWKLKY------------------------------------------------- ------------------MG-------HRKKSAPRHGSLAYHPRKRASNFTGRWRSW-G- D-LSYD---TPTILGFAAYKAGMTHVVLIEDKKTSPYY--GHEVIKATTVLDAPPAIVCA IRAYSSA--GNA-LK---ALGDVWAGELTED-----L-----RRRF-------------- ----TTP---KDY------SMDKE-----------------------LLELEKR------ ---IK--DATELRLILHTQP-----RLTSLPKKKPDIMESKISGGSLK---DQWKFAKEL LGN-EIKVSSIFKEGEYIDVSAVSKGKGLQGPMKKFGIKKLPR--KSRKTVRG--VGSI- GPWT-PARLM-WTIARSGQMGFHQRVEYNKRILKIGI---DPK--EIIPAGGFLNYGVIR GDYLLMLGSMPGPRKRMIRLRKAIR---P-P-KIIP-ETPA-DLVYISLASKQGK----- ------------------------------------------------------------ ---MSPTFGYSIT---------------------------------------GLDPDRTA I----------------------------------------------------------- -----------ASGRDIR-CSPKHAREICNAI--KGMMIEDAKVFLDEVVLHKQAIPFKR HNK-KQAHRK-----GLDRFKWPA-GRFPVKAAQAVINILANAENNAEFKGL-DLDRVRI IHAATHFGRKIKKYIP-------RAFGR--STPYFKTL-THIEIAL-------EEE---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRIKVQR-------------RGRGSPTFRATKKRKR- GTVKHP-N-PT-TYENQPLEGE----VIGFEHERGRSAPLARIRYSNGKK-LYMIAPEGV AIGETIKVG--------------TPE---IKIGNTLPLKDIPEGTSIFNIESQPGDGGKF VRAGGTYATVVTR-DP--N-KVIVKLPSGKTKQYNPACRASIGIVAGGGRTEKPFVKAGN KFHHCRAKNQKYPVNRGVAMIAASHPHG-GGQKQHI---GKK----SSTVSRNAPPGRKV GLIAARRTG-------RKKR---------------------------------------- -------------------------------MDEEQISYFSEEEKSEILDMWKNEPMRQL KISKVIVHMGVGASGERLEKAIRVLESL-TSQ-KPVKLLAR--K--TIRDFGIRKREPIT TKVTLRGE-KA-EEFLTRALTVVDNKIKYSSIDTYGNFSFGIKEHIELPETTYDPSLGIF GLDVSISMAHP-GYRISKRRKYKRKIPKNHRVSKLETMVFLDTKFKVEI-VKEYVVSYY- --- >GCA_003694495 -----MV-VNKR--KKLTR-YRGST--THGGGSMKKRR-GAGHRGGRGM-AGGGKRADQK K---------PSILKQY-------------GSS-----Y-F--G-------KH-GFKNK- -TTK--RI--KA-----L-SLSKLNS----LVE------KNI-SP---------KNGVYV VN--LKDLG--YDKVL----GSGTINKKL-KLTT---DYASSKAVSKIESLGG--TVE-- V---------------------------LNSSEEEWEDVEEEKR---------ED----- ----------------------------------------------------------MI E--------------------RKFVAQKMKELLV----------------QNFMGQQL-G KGKYSYFEIK------KTPLGEKIIIFTTRPGLIVGKKGENIKYLTQQLKTKFNMENPQI EVA-EVYNPDLDAQTV----------AEQIVNVFERYGPKRFKAIGYKSLQRIIDAGAMG AEIVISGRGV------------PS-------------SRAKTWRFY-------------- ----AGYLKKSGDISQNKVVRGESVANLKSGSIG-------------------------- ----------IKVAIM---------------HPDI----------VLPDRI--------- ------------------------E-V------------H-KPEDQT--VKIEAVTEEK- ------------------------------------------------------------ --------EEEEAK-----------EDKPKKA---------------------------- ------------------------------------------------------KKKKVK ------------------------------------------------------------ -------------ESDKSND---------------------------------------- -----SKSEKAEEVKE------N------------------------------------- --------------------------------LPES------ENKEE------------- SKVKENGKD-------------------------------------MKADVLSLDGKKLK TIDLPSQFEE-SYRPDLIKRAVLAVQSHKRQPYGADPEAGFRHSAKLSRRRR-K---YRG GYGRGMSRVPRKVLSRRGTQFSYVGAIVSSTVGGRRAHPPK-----SEKIWDLKINIKER RKAIRSAISATLNKLLALARGHKV---K---ELPLIVESKIEDLKKAKEVESVL---KAL GLNDELERCKE--KKVRAGKGKARGRKYKRKVGPLLV-V-S-NKSS-------------- -----LTKAALNLPGVDVAVVDSLNAELLAPGTHAGRVTVWSEKA---IERMKSENLFTE NI----------------------------VKPSKKEAKAQ------------------- ---------------------------------------------MSSSKT---KVVPFR RKREGKTDYKKRMKLL-ASKKPRLVVRKSLKNFSAQIIEYDPKGDKVVVSAHSREL-IKL GW----KGYRRNVPAAYLVGLLCGAKAKAK-GIKEAVLDIGLYPSVKGSVLYAALKGVLD AGIEVPH--DESVLPP------EERLIGAHTKN--------------------------- -PEQSKKNYEEVKEKI------------LKVKK--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAI-KAKVTRGLPLGTILETCDNSGA KVVRLIGVKG--HKTVKRRLSAAGVGALVNVAVIKGRADVRKQ---VLPAVIVRQKKAYR RPDGTRVKFEDNAVVIMKDDKAGTPKGTIFKGAIAKEAAE-RWPGIAKVASIVV---MAK K---------------------EQAARNIG---LD-VKP-PKES-----------C---- -N----DPHCAF------------------HGSVAVRGRVFVGNVIKQDINKTVTVEWPR QNYLYKYERFEKRRSRVKVHNPPCLN--VKVGDKVKIIETRPISKTKNFVVIEK------ ----------VE------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MARKEYTYRGKKIE--------------------ELKSLSLNDFAQLL PSRQRRTIVRGF------SEPQKRLLEQVKKFKEG-----KRK--KPVKTH-CRDMI--- ------ILPEF----------------------------VGLTIHVHNG--------KTF S-----------PILIKPEMLGHY----------------------------LGE----- ----------FAHTR-AKVAHSS------------------------------------- -------------PGVGA-TR-------------------------------SSSAVSVK ------------------------------------------------------------ ------------------------------------------------------------ ------------MQKARIKLASADITKLNEMINSIKDIVEKTKVTMRGPIPLPTKRLKIT TRKSPDGEGK-------ASFDNFEMRIHKRLIDL-GLDERALRFVMRVPIPEGVSISIEI LE---------------------------------------------------------- -MKS--VFSNL-----WKRSVQPRKQRKYLYN-ASLHLKRKIVLSSPLSKELRKKH---- ---------------------NKR-TMVVRKDDTVKIMRG--QFK--GKSGKVTKVNSKD GKVYVEGIELIKKDGT-KTMYP----------LRASNLMITSLFLD-------------- ---------DKK-RK-----------------------------------KILERK---- ------------------------------------------------------------ --------QEKKNG---------------------------------------------- ----------------???????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????----------------- -----------------------------M-AMN-DTLANALCVIMNAERIGRKECTIKP VSKVIKVVLDIMNKESFVGKYEEIDDGK-GGILKLNL----------------------L GSINKCGVVKPRFSVKKDGYEKFEK--------------------RYLPSKDFGVIIVST PKGIMTHIEAKEKGLGGRLLAYVY-----------MHTYI------------------KM IPEQRL------------TKTLEIPEGVTVELN-E-----SLKVK--GPNGEVNKNLN-H P-T----VEIVV-EENK-VIVK---PK-KLT---KKEKSLINTYVAHIKNMFKGVTEG-F TYKLKVCSGHFPMSVSVE---GDK--LV-VKNFLGEKVPRTAKLL--PNVKVEVNGD--- ----DVVVTGADKEAVGQTAANIEQSTRITN---RCKTR----------FQDGIWITEKA GKVM-------------------------------------------------------- ------------------------------MHKPHRGSMQFWPHKRAKRAYARLRSW-L- NRSK-----EVKLLAFPGYKVGMTHILMQEPNPNAPTK--GMQIQVPVTILECPPLKAYS VRYYKKT--LDG-MK---VVSELFSKKLDKS-----L-----SRKI-------------- ----KPT---K-----------KD-----------------------GKEPE-------- -------DFDDVRLVVYTTP-----VFTGLEKKKPELFEIGIGGNDAK---QKAEFAKSL LDK-DIRLADVLKEGHLVDVHAVTKGKGFQGTVKKFGVKILQH--KSEKKKRG--IGNL- GSWT-PKKVQ-FTVAQPGKFGYHLRTEYNKLLLKVGN---NPK--EINVKGGHLHYGNVK NDYVLIKGSVPGSVKRLVTMTEPIR---P-M-LKFK-PFQP-EIKYISLESKQGR----- ------------------------------------------------------------ -----------------------------------------------------MANEHTA R----------------------------------------------------------- -----------VTGRDLP-ISRKHCVEIGNLI--RKKPLSKAKNLLEGVMSKTVAVPMKK FNF-DTGHKR-----G----SVGP-GRYPYKASMFILKLLGSIEKNAEHKGL-NTESLVI KTFMANKGTSQWRY------------GR--QRRRRAKR-TNIIIEV-------EELYPK- ---------KEQPKAKD------------------------------------------- --------KNVSKPKEVKKE---------------ESKPE-----VKQDLSKSE------ ----------DKQKKASK-PNKEAKQDV--SKSEVKKEES---------SKPKEVEQEET ------------------AKEAKK------------------------------------ ---------------------MGKRIITQR-------------RGRGTSTYKSPSHRYK- GQIKHR-K-YDDLEKTGVLFGK----IVDLIHCPGHNAPLAAIEFENKEK-ILISAPEKV KVNDVVASGS-------------AAP---VQVGNTLPLKNIPEGTLVYNIENIPGDGGKL VRSSGSAARVLTK-VG--E-KITIMLPSKKVKVLNSNCRATIGMVAGGGRKEKPFLKAGK KMHAMRARNKLYPRTSGVAMNAVDHPFG-SGRGRHV---G-K----PKTAPRWAPPGRNV GLLKAKKTG-------RGK----------------------------------------- -------------------------------MA----------------------SMKEI QVEKVTLNIGTGKPGPELEKALKLLEQI-TGV-KPVETKTQ--K--RIPSWSLRPGLSIG AKVTLRGE-KA-VEVLKRLLDAVEYYIPSKKFDNEGNFSFGIKEYIDIPGMKYNMDIGIM GLEVAVTLKRP-GFRIKRRMIKTKKIPRRHRISKEEAIKFMQENFNVKT-EQEGEE---- --- >GCA_011364985 ----MKE-KRKS--RKINK-LRGQR--SAGYGYTKGHR-ASGQRGGKGN-AGSKKHHYIK VVQ-----EDPR--------------------------Y-F--G-------KW-GFKRPQ KLQD--NK--RA-----V-NIGDIDK----AADRLTE-AGKA-TK---------KGKKYT ID--VTSLD--IDKIL----GSGKVTKPLDLVGV---KECSSRAQEKIVAKGG--SID-- IAAE-------------------------------------------------------- -----------MSSNND---EYVDIREAVLKALPRSAAVTTVEYEGPEIAIYSKAPKILL DD----GDKI-----------KALARKMRKRLVV---RSAPEVRLPHEEAEKTVRQLVPE EAEITSIDFD--------ESRGEVVIEAQKPGLVIGRSGSTLREITRQT-----FWRPNV MRT-----PPIESKLIKQIRYIVQSEAANRNRMFRDIGQRIHRPALLN--NGWIRLTAFG GFKEVGRQCMFLQTS-------ESNV--LIECGVNVG--APSRAYPRLDMPEFNLNEVDA VIITHAHLDHCGMVP----------FLYKYGYRGPIYMTAPTLNLSTLLQLDYLDVAERE GKLRPYRDRDVKESILHTVTLNYGEVTDI--APDVRL-TLHNAGHILGSAI--------- ----------VHLHIG-DGQY---N-LAYTGDFKFGRTRLLEPATFTF-PRLETLIVES- -----------------------TYGHPTDK----------------------------- ------MPPRQEVERKFASII----KRTIERGGKVLIPVLAVGRAQEIMLVLEDLVTKKR IPKIPVYIEGMIAQATAIHTTHPDFLSKKIREMVFHQGVNPFLNEIFNAVDNPDQREEIV E-GEPCVI----------MATSGMLAGGPSV------EYFRLLAPDEKN----TLV---- ----FVSYQGEQTLGRRIQKGWKE---------------V-------------------- --QMRNREGQTTVVPVNMEVETVEGF-----------SGHSDRKQIL------------- ---------------NFVKRVNP---------VPERVLTCHGEASKCMNLASTIHKSLNI DTKALQVTETIKLR-------------------------------MASVSTYSLKGKAGS KVKLPQQFET-PYRPDIIKRAVLSLQSKKRQPHGVDELAGKRNTAQSWQTGH-------- ----GRSRVPR-VKG-SGTLAANKAAFAPGTVGGRVAHPSE-----ARKVIIERINKKEN RLAIRSAIAATADQRIIGYRGHKVG--SV-PEIPLVVDDKIETLQTTKEVRDVV---MSL GLEDDLFRAIQG-RGIRAGKGKMRGRRKKTPKSFLIV-V-G-KDQG-------------- -----IRKAARNLPGVDVAVVHGLNAELLAPGTHAGRLVVWSKSA---IEKLEQEALFM- ------------------------------------------------------------ ---------------------------------------------MAQGPT---YRVKFR RRREGKTNYYKRRRLL-LSRKPRLVVRKTNSRTIVQVITANVVGDMTIASAQSTEL-KKY GW----DAGRANLPAAYLTGFLAGLRAKAN-GIDTAVLDIGLIPPVRGSKVYGALKGAID AGMDVPH--DEEIIPD------GDRLSGKHIVDAFKYYTDNP--ADGHVFSKLGK--KKT AITTIPKQFDAVKKAMLETP-----KTDLKKKSKK------------------------- ---KPAAKPA-------------------------------------------------- --------------------------------AKKTTKKEKKPKLEETPPRAVPRKPK-- PKKLISRGRGKKGKK-----MSR--KVGRG---IRKF-IPRIARGLPVGAKVLCADNSGA RELQIITVFG--YKGNLRKVGKAGVGDRVNVAVTKGKQELRKQ---VLQAVVVRQRKPYR RPDGTWMQFEDNAAVLIKPG--GEPQGSELRGPMAREVTL-KWPRVAAIASKIVMVVMAK EA---------------------TKVRNIG---IPNVET-PERT-----------C---- -D----DENCPF------------------HGNLPVRGRILEGLVTSVKMHKAITFQTDY FSLVKKYSRYERRRSKKHAYLPPCID--VTVGDFVKVVECRPLSKTISFVVVSV------ ----------TK----------------------------------------ADTDVEE- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------MSSKSEPMYRGYKLS--------------------DLVQMNMDTLIELL PSRRRRTLRRGL------PQRQKKLLMKLRAARKAK-KKGKDI--I-VKTH-CRDMV--- ------ILPEM----------------------------VDLTIGVHNG--------KEF V-----------KVKILPQMIGEV----------------------------LGS----- ----------LSIPT-RQVKHGS------------------------------------- -------------PGIGA-TK-------------------------------SSAYVPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------TQKARIRLSSTSTEHLDSVCNQIKRITRKTGVRMAGPIPLPTRKMVVP TRKTPCGQGS-------ESWDKWEMRVHKRLIDI-DADERAIRQIMRVRIPDSVYIEIEL TG---------------------------------------------------------- -MRF--RKMTK-----KPSSKSPRKQRRRI-K-GPIHSHKKM-LKCRMDEFLHEEY---- ---------------------GIR-SLVPKKGDLVRIMRG--QFR--DTEGKIVGINYSK VKIYVENATTTKADGK-EAQVP----------VHPSNLMLVKLELD-------------- ---------DD--RK-----------------------------------RILEKKMIGM ------------------------------------------------------------ --------AESE------------------------------------------------ --------------------------------MG-KRPGHCYREA--------------- DR-QPFVR---------KRFIHRQ-PASRIVSFDMGET----GGDFPV-EVSLYGLERC- -QIRHQALEAARVASNRHM-TKYAGRR-NYHLRMRVKPYHYLRENKMIS-GAGADRVQDG MRKAFGKVVGVAARVRP-NQALITIRT---T-EQHLKTAMRALEKAAPKM--PTPCKI-- ---------------------Q-----FDKIDPDLKRRLGYGS----------------- ------------------------------------------------------------ -----------------------------M-TLL-DPLADAMSSIYNSEVVGKPEVIIEP ASNLIEKVLRVMQVQGYIGEFEHIDDGK-AGRFRIQL----------------------M GRTNKCGVIKPRYPVRRDGFESFEK--------------------RYLPAYNFGVLIVTT PQGVMTHNEAKKLGIGGRLLAYVY------------------------------------ MSKGAVY-----------EKRIEIPSDCQVTLEDR-----TFTVS--GPKGTLSRTFP-E P-Q----TTFTI-EGNE-IVAS---TE-ISR---KRSKALVGTALAHLRNLFVGVQFG-Y TYEMKIVYSHFPITVEVK---DNE--LL-IKNFIGERGIRKAKLI--GDVDVKVTED--- ----EVIIDGIDIEHVSQSAANIQLATKIRD---KDRRV----------FMDGIYVIKKR KGESVKSIV--------------------------------------------------- ------------------MA-------HRKKHAPRHGSLAYLPHGRASKFLPRIKNW-P- E-YDDS---AAKLLGFVGYKAGMTHAVVTVDNPNSPFK--GQETVIPVTVIDVPPIRPFS IRGYNVT--VYG-KQ---LVTEVLAENLTED-----L-----RRVF-------------- ----PMP---KSY------DFEAK-----------------------LQEFENQ------ ---LD--SLAEIRMLIHTQP-----RLAGVPKKKPDITEYKIGAPSVT---DAFEYAKEI LGA-DIRVADILEEGMLIDSIAVTKGHGFQGPVRRWGIRILQH--KSRKTKRG--VGCI- GPWS-PTNIR-YTVPRPGQTGFHTRTSFNNIIVKLGE---RGE--EITPSGGFVNYGVIR GDYVMLKGSVPGSVKRPVRLRFAVR---P-K-RKHE-VKPI-QVSYVSTTSKQ------- ------------------------------------------------------------ ----MPTYGYSII---------------------------------------GIDPDRTA V----------------------------------------------------------- -----------ASGRNMR-CSPKQSREICKAI--RGMMLDRAIELLEDVIQEKAWIPYRR HKK-KRGHHS-----GMK--KWAA-GGHPVKASENILKILKNAEANADSKGL-DIDRLRI IHAAASRGRTYKKYIE-------RAFGR--SSPYFKNT-THVEIVL-------EEVI--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGRRILVQR-------------KGRGTTQWRSPSHKKI- APARHP-K----WAPEKTYTGK----VTNLLHEAGRGAPLAEVRYENEARIHYMIAPEGI MIGQAVECGE-------------DAT---LQNGNTLMLQHIPEGTPVYNIEGSPGDGGKY VRASGLTATIVSI-DP--T-KAMVRLPSGHQKSFSPKCRATIGIVAGGGRTEKPFLKAGA VWHHTRGKARKWPVVRGAAMNACSHPHG-GGSHQSP---G-R----PTTVSRNAPPGRKV GNIAARRTG-------RKK----------------------------------------- -MIDLPNERLFKADW---------------EHN----------------------PMRKP FVAKVVVDICTG-GGEPLSRASTILEEL-TGQ-IPTQSRAR--Q--TVRDFGIRRKEPIA VRVTLRDE-KA-EDFLSRALQAKEKILLVRNWDDDGNFAFGISEHIDIPGVKYDPQLGIQ GMNITVCVERP-GYRVKRRRRRRTKIPYRHRLTPEESMAFIAERFDVEI-LEKERERTYL F-- >GCA_003558875 ---------MGKVNHKNDE-LSGLI-------------------------SDLKRLSIEK K---------VKIWKR------------------------L----------AE-DLEKPS RSKR------------II-NIYKLDRN----------------TK---------DKELVV VP----------GKVL----GTGSLGHAV-DVAA---FSFSEDAVKKIAE-KG--KVL-S IRDLMKS------------------------NPEGKNVRIMG------------------ ----------------------------------------------------------MI E--------------------RKFVSQNMKEFLV----------------KDYLFKEL-T RVGLSGVALQ------RTPLGEKVIISASRPGLVVGKGGANIARLTKELQARFDLENPQI EIE-EVKDPRGNAAIT----------AEMIANSLERFGSARFKGVGHKAISSVIDSGSLG VEILISGK-I------------PS-------------SRAKTWRFY-------------- ----EGYLKKCGDVAVSGVDESKQVAKLKTGIVG-------------------------- ----------IQVKIM---------------PSST----------VLPDKL--------- ------------------------A-I------------K-D-------IS--EVEVSD- -------------------------VASTES--VEEAADEGVEEK--------------- ---------AESVK-----------ESK---K---------------------------- ---------------------------DTVKE---------------------KDEKEVV AEDTDEV----------------------------------------------------- ------------SDKKAVKKTT-------------------------------------- -----KKATKKTTKKTTKKATKK------------------------------------- --------------------------------TTKK------AAKKA------------- EVVEDEAVGAE---------------------------------M-MELKILNKDAKEAG KIKLPVQFNE-SVRSDLVKRAVLVIQANKRQRYGASAEAGKRASAYVSKRRR-A---YKT TYGIGQSRTPRKVLSRSGTRFNWVGAFAPQTVGGRRAHPPK-----ASKSWSQKINFLEN QKAIRSALSATMIPDLVKKRGHVVP--S---NYPFVVSDEFGSFSKTAELKKVL---SSL GFDKELERVST--KKVRAGKGKVRGRKHRSKKGVLFV-V-A-NDKD-------------- -----LLRASNNLPGCEVVVVDSLNALVLAPGAVPGRLTLFTESA---IKRINDESLFLS SSEKKVKAKQ-EKASS--------NDSKKEAKPVKKTAKKVSKKVVKKP------VKKVS KVAKKVVKKEIKDE-------------------------------MKSTTT---YTVKYR RKRDGRTDYKSRLNLL-KGKTDRLVIRHSNTKLVLQIVRYNPDGDKVLLTVNSSEL-KKM GW----SHSCKNIPAAYLAGLLLAKRAKEK-KVAKAILDLGLKSPLKGSKVFSALKGVVD GGLVVPV--SEEVFPS------EERIKGEHVAKFLD------------------------ KHKSIVDDFEKLKNKI------------KE------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKAI-KAKIPKSLPTGARVETCDNSGA KLLKIFSVRG--HKTVKGKAPSARVGDLVHASVVKGKPDMRKT---VVLAVIVRQKKEYR RIDGTRIKFESNMAVVVKDDK-GNPKGTIFKGPIAKEACE-RWPGIAKVASIIV------ ------------------------MDKN-------------------------------- ---------------------------------LSTRGRRFTGIVISDKMTKTVTVEWER RKFVKKYERYEKRRTRIKAHNPEEVD--AEKGDVVVIEETRPISKTKNFVVTKI------ ----------VK---------------------------------------------KAN E------------------------KSDEQ------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKIFTYRGKTLE--------------------ELKALSVKDLADLF PSRQRRKLKRGL------SEGEKKLLEKLKRKDN-------------VKTH-LRSMI--- ------VFPEM----------------------------VGKTLRVHSG--------KEY L-----------PISISEDMIGYY----------------------------VGE----- ----------LVMTR-KRVGHTG------------------------------------- -------------PGVGA-TR-------------------------------SSSGATKR ------------------------------------------------------------ ------------------------------------------------------------ ------------MQRARVKLASTDISKINATCEYIQGIAEKTGVVIKGPIPLPTKKLRVT TRKSPCGDGT-------ATWDRYEMRVHKRLIDL-GVDERALRLIMRVPIPEGLNIEIEM LES--------------------------------------------------------- -MKS--QFSNS-----WKSSTQPRKQRKFRYN-APSNIRRKF-LAVNLAKDLRAKH---- ---------------------GAR-SAKIRSGDKVKILRG--NFR--SKTGTVDKVDLSN LKVFVVGIEVSKRDGS-KAKVP----------LNPSNLQIVELKLD-------------- ---------DKK-RKD----------------------------------KFSVKKKV-- ------------------------------------------------------------ --------EDK------------------------------------------------- --------------------------------MAKLMRAVAWRRL--------------- -E-RPYTRKSKYR---KKAFVRAV-PNNKIVKYVMGNQ----KKEYSH-IISLKSKADI- -QIRHNALEAARKTANKLL-ETK-APV-NYKLRIKVYPHHILRNNPLAA-GAGADRMSTG MSHSFGKAVGIAAQIRK-GQSIMDVEV---N-KDKLQVAKTALDRARKKM--PCDCSI-- ---------------------I-----IEEKTAS-------------------------- ------------------------------------------------------------ -----------------------------M-SLN-DPLANVLSFVNNYERLGKKEVLTKN NSKVIRKVLEVMQEEGLIGSYEELDDGK-GKVLRIHL----------------------I GSLNKCGVIKPRHKVKVEDFEKFEK--------------------SYLPAMDFGALVVST NKGIMSSKEAKKQNLGGTLLSFAY-----------------------------------M KHEELL------------E-IITLPEGCTFTCDNK-----VMIVK--GPKGELSRPLP-D K-K----IKVVV-KDSE-VSLS---YK-KAT---KREKRMLLTTKAHINNMLKGVTQG-F MYKLKICSGHFPMNVSLK---GEV--LE-IKNFIGEKVPRTLKIK--PGASVKINGD--- ----EIVVESTDKELAGQTAGSIEKLTRRPG---FDKRI----------FQDGIYIVEKD GKKLS------------------------------------------------------- ---------------------------MASKGRPRFGSMGVWPRKRAKRPYARIRSV-P- V-VK-----EAKPLFFPAYKAGMTRVSVLGTDKNKTNF--GIEESQGVTILECPPIKVAS VRFYKRE--GHE-EL---VAKQLNFKA-DKE-----L-----FRKI-------------- ----LRI---KD------EK-FSS-----------------------VKDLDAIN----- ---PE--EFSDLTIQVYTLP-----KQIDL-KKTPELFELDLGGSF-E---EKLEFVKNK ADK-VITINEVFKEGQLVDVHGVTKGRGFQGPVKRFGIGLKDH--KSEKGRRA--PGSI- GSWIGQAHIS-HRIARAGQTGYHLRTQHNNLIMKLGD---KPE--EVNPKGGFINYGLVK SSYIMIKGSVQGAKKRLLFLAEPVR---S-N-KKVS-FSPG-NIKHVSVDSPQGR----- ------------------------------------------------------------ -----MKTKYAFQ---------------------------------------GL-KENMA R----------------------------------------------------------- -----------AISKDLG-ISSKVSIEIANFL--RGRTSAEAKVILERVLKKKQPIPFKR FTD-GVGHRK-----GA---GLAA-GRFPQKASEAFLTIIKQCEANAQAKGL-SS-DLRI VHLVAQRGTNMFRH------------GR--QRRRMYKR-THLEIVL-------EEFES-- ----GDKASKSSKKAPVSKP-----------------------KAEPKKEEKKDE----- ------------PKKEAPKKDVPKK---------DEKKDV---APKKEE-KKEV------ PNKDEKKDVAPKKEEKKEVPNKDEKKDV--APKKEVKKEEP--------KKEA-PKKEAP ------------------KKEEKKEAPKKDEPKKAPVSDDDSKNIKNDESLPNKDQK--- ---------------------MGKNLIQQR-------------RGRGTTRFRAPDFRYK- GEIKM-----LNKA-----SYV----VKNLVRCPGHSAPLIEAEYNDRST-SLLIAPEGI SVGDKVDLT--------------SQE---VKPGNIIALKDIPEGTSVFCIEAKPGDGGKF VRGSGSFAKVVGK-SS--N-NVTLLLPSKKQKAFHPNCRAMIGVAAGGCRVEKPLLKAGK KHHIMKSKNKYYPVVSGSAMNAVAHPFG-NKRTSRK---S-K----ARPAPRNAPPGRKV GMIKPRRSG-------RRNK---------------------------------------- -------------------------------MN----------------------LMKNI RIEKVTLNIGAGKEQKELDKAVKLLENI-TGI-KPVKTTTN--K--RIQSWGLRPGLPIG CKITLRGD-EA-LKMVDRLLYAKDNVLDESCFDDEGNISFGIKEYVDIKDAKYDPAIGMM GLQVTITLSRP-GFSVKVRRLRPAKIPRSHRISKEEGIKFMKDKYSIKT--GEEL----- --- >GCA_007117145 -----MT-INKR--KKITR-MRGSH--THGGGAMKKRR-GAGNRGGRGL-AGTGKRGDAK K---------PSHWKN---------------TE-----Y-F--G-------KK-GFHSI- -TRK--KV--DS-----I-NIKDINQ----KIAGWLE-KGIA-EK---------TGSEII LD--LKKIG--YDKLL----GVGTPDYKL-EIHA---LQVSKKAKEKIEGAGG--KVV-- L---------------------------PKTE---------------------------- ----------------------------------------------------------MI E--------------------RKFVSQNVREYQV----------------KMFLFTEL-T RAGLADVNLQ------RTPLGDKILVHASRPGLVVGKGGANITKLTNDLKNKFGLENPQI EIE-EVKDFRGNAAIT----------AEMIANSLERFGTQRFKGVGHKTLETVMSSGALG VEILISGK-I------------PS-------------SRAKTWRFY-------------- ----QGYLKKCGDISISGVYEAKQIAKLKTGVVG-------------------------- ----------IQVKIM---------------PGTT----------ILPDKI--------- ------------------------E-L------------L-DEPVTI--IE--EVQDEK- ----------------------------TQL-ELEKGSKEPVEPKLKDEKQKVKEVNVVE VSEKEEKIIKETIK-----------EEKP-AK---------------------------- ---------------------------KEPEK---------------------KVEKPVE -EKKVKK----------------------------------------------------- ------------AEKKPAKKEPE------------------------------------- -----KKAEKTEKKPAAKKPAKK------------------------------------- --------------------------------ETKK------TEKKT------------- ETKTSQSKKSQDKKK????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????------MKTK---YTVQHR RKREGKTDYRKRLELL-KGRKDRLVIRKTNTQIIIQLVRYAEEGDKVLYTFKSSQL-KKQ GW----NHQPNNLPACYLAGLFAGKQIIEK-KVKTAVLDIGLRTPKKGGKIYSALKGLVD AGLKIPV--GDNIYPT------EERMSGKHI----------------------------- -NEKVEKDFEKIKAKI-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MKSI-SAVITKGLPVGSRVETCDNSGA KVVKIFSVKG--HKTVKGQLPAGGVGDLVKVSIIKGRPDMRKT---VQWAVIVRQKKEYK RINGTRIKFEDNSVVIVKDEK-GNPKGTIFKGPIAKEACE-RWPGISKVASIIV------ ------------------------MENK-------------------------------- ---------------------------------ISTRGRTFTGTVIADKMAKTVTVEWER QKYIPKYERYEKRRTRVKAHNPENIN--AKEGDIVVIKETRPLSKTKHFIITEI------ ----------VS---------------------------------------------QK- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVKKIFKYKGKTLE--------------------ELNAMSHVEVAKIL PARQRRKIKRGF------SDEEKHLLEKLKAKGT-------------AKTH-LRDMI--- ------VLPEM----------------------------IGKTIKIHNG--------QKY Q-----------EVLIQEESIGCY----------------------------LGE----- ----------LVLTR-KRLTHGS------------------------------------- -------------AGVGA-TR-------------------------------SSASVSVR ------------------------------------------------------------ ----------------------------------------------------???????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- -MKS--RFTKT-----WKESTQPRRQRKYRYN-APIHIKRKF-LSVNLTKDLRVEF---- ---------------------GTR-NVIPRKSDRVKVLRG--SHK--GVESKISDVDVKK GIIYLDGIENTRGEGN-KSRIP----------FKPSNLQIVDLDTS-------------- ---------DKR-R-K--------DKL-----------------------KSLKETRK-- ------------------------------------------------------------ --------ENDK------------------------------------------------ --------------------------------MAKLMRAVAWRRL--------------- -E-RPYTRKSKYR---KKDFIRGV-PTNKIVKYVMGNQ----KKEYEF-RLTLVSDHDI- -QLRHNGLEAARKTTNKHL-ERK-APL-NYLFKFRIYPHHVLRNNPLAA-GAGADRMSTG MSHSFGKAVGIAARVKK-GQPVIEVHV---P-KEKVQVAKEALHRARKKL--PCGMRV-- ---------------------L-----VEKN----------------------------- ------------------------------------------------------------ -----------------------------M-SLN-DSLANVLSHIDNYEKLGKKEVITQN NSKLIRGVLEIMNKQGLIGGFEEVKETN-GKKLTVNL----------------------L GTLNKCGVIKPRHRISVDDYKKFEK--------------------RYLPALDFGVIIIST NKGLMTHQEAKKQNLGGTLISYAY-----------------------------------M EPKKPV------------ETTIEIPEGVQVEKEGF-----LIKVT--GPKGELTRRIT-D K-S----TIVNI-TAEN-VEIK---FK-KPK---KTRKKNMNTLSAHIRNMIKGVNDG-Y TYKLKICSGHFPMTVSLK---GDV--FE-VKNFIGESVPRRLKLK--QGVEVKISGE--- ----IIEVTSTDKELAGQTSASIETMMKRPG---FDKRI----------FQDGIYITEKD GKAV--------???????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????--------- -------MNYSMQ---------------------------------------EM-KENMA K----------------------------------------------------------- -----------AYGKSLG-ISTKTSIEIANHL--RGRTTTKAKWILEQVLQKKQAIPFKR FTD-GVGHRP-----G----GIGA-GRYPQKASEEFLKLVKQAEANAQAKGL-SE-NLII VHLSANKASSQFRQ------------GR--QRRRKFKR-CHLEIVV-------QE----- ------------------------------------------------------------ --------------MDAPKKKAEKK---------TEEK---------------------- ----------PAKKE----------------PEKKVEQPVD--------KKPS-VKETKP ------------------AVKENKE----------------------EKQIPKEDKK--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------K-TD--K-TITILLPSKKQKEFHPNCLAIIGVAAGGGRVEKPLLKAGK KRYMARSKNQMYPIVSGSAMNAVAHPFG-NKRTSRK---S-N----AKPAPANAPPGRKV GMIRPRRSG-------RKNK---------------------------------------- -------------------------------MN----------------------KMKEI RIEKITLNVGAGKDQKVLEKGVKLLKNL-TGI-EPVKTITQ--K--RIQGWGLRPGLPIG TKLTLRGE-EA-KKMVERVVYSKDNVLNLSHFDDNGNISFGILEYVDIKDAKYDVDIGMM GLQTSITLSRP-GFRVKNKRIRPGKISKDHRISKQEAIDFMKKNYNVKI--GEEQ----- --- >GCA_012928605 ------M-ATRL--RKTRR-LRGGR--HMGWGQVAQHR-ASGHKGGLGV-SGMMKHHYSS MLK-----YDPD--------------------------H-F--G-------HD-STKPPH PNIT------KKW----T-SVRDLDD----LFTKF-G------KE---------EGGKKI VD--LKSAG--YEKLL----GGGKITNAY-SVKV---QQFTASAEEKLKAVGG--EVL-- SDNG-------------------------------------------------------- ---------------------------------------------------------MSA V--------------------KNVIKDNYNMMLL----------------KDYLREAI-K DAGFSHAEIS------KTPTGTRVALHVTRPGIVIGRKGTGIRALTEKLATDFNLKNPQI SVV-EIDKPELVPGVM----------CNRMAAHIER--GTAFRRATMWTLKQIMENGAMG VQITISGK-L------------RG-------------DRSAFEKHT-------------- ----AGILPRAGHHAEIIVEQDIAHVKTKMGLIG-------------------------- ----------IRIRIAR--------------------------KDKLIPEF--------- ------------------------E-M------------RDEKPKKVK-QEEKTEKVSDQ TEKVSDQ------------------TEKVSD----------------------------- --------QTEKVS-----------DQ-TEKV---------------------------- ----------------------------------------------------SDQTEKVS DQTEK-------------VSDQ------------------------TEK----------- --------VKTESEQIAIEEEKMKSLET-------------------------------- ----LEEEENRLK----------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MKTTVYTTSGAKDG EVELPIVFMT-PFRRELIHKAFTNLTSHKFQPQGRHPTAGQDVVADSNNP---------- PTGQGVSRVAR-ATG-GGGGRSGQGAEVASTRGGRQAHPPI-----VGKVIYKKLNKKEN KLALCSAIAATASKDLVESRGHKVE--GI-KLFPIIVSDDIESISKTSEISKVL---DSL NLSQDVKRLES--RKIRSGQSRLRGRSKKVGKSVLFV-T-T-NSSN-------------- -----LRKAIGALPGVEAKNVKDLSVLDLAPGSDPIRLTVYTKSA---IKEIGKIKSTHL ELMVKTQ----------------------------------------------------- ----------------------------------------------------MAYSKILR RLREEKTNYKKRGTML-MGKRDFITVNITNENTLVQILKPGMTGDTVVASAHSRYL-LQK GW----KGSRKSVPAAYLTGYLAGKKALGK-GANDAILYTGTR--RYTQRMAAALKGVID AGVKVPA--DEETFPP------EDRINGEHLTV------KNDI----PKIKS-------- ----------TIDSEIK------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------MAK--QAGKG---VEEF-RPYVTRVIPVGAQIVCADNSGA KILEIINVPR--HKTRVSRLPAAAVGDFCNVVVKKGPAVLRKQ---VHGAVIIRQKYAIR RLNGVRVCFEDNAAVLITPE--GETRGTDIKGPVAAEASE-KWPRVANLASMVV------ ------------------------MTLNIG---LK-VKE-PKRK-----------C---- -T----DRNCPF------------------HGNLSVRGKLFDGKVTGSKAKQTITIQKEI AIYFTKFKRYARGKSTIHAHVPNCID--VESGDFVLTAECRPISKSVSYVVVEV------ ----------RA------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MVKQFSYRGIPKE--------------------ELENTSLEKLFLLF NSRQRRSLTRGI------TDGKRKLIEEIKSAKA-----GKLK--NPIKTH-LRDLI--- ------ILPYM----------------------------VDVTVDVFSG--------KEF V-----------PVVIKTEMIGHY----------------------------LGE----- ----------YVITN-KKVSHGA------------------------------------- -------------PGVGA-SR-------------------------------SSLYVPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------TQTARVKLTSTSLKKLDGVCGEIMGIGKKTGVKIKGPTPLPVKRLHVA TRKSPCGSGT-------ETYEKWEMKMHRRIINI-SADDKAIRQLMRLKIPDDVYIELSL T----------------------------------------------------------- -------------------MKPTKMRNKMIYR-ATYTTKSKQ-LGSALSKDLHKKY---- ---------------------GRR-SVRVIEGDSIRIVRG--EYK--GVDGKISKISTQK NSVSIEGIKKEKTKGD-KFDVY----------IHTSNLVVTSLNTG-------------- ---------DKW-RM-----------------------------------ARLEGKDPR- ------KQPKDVPKEKPA---------GEEIVKK-------------------------- ------VSKETKEVKKTEKKEDEK------------------------------------ ------------------------------------MHGANYRRG--------------- -RGQAYTR---------KEYIKGK-PQIKIAKFQGG-K----RGTYQY-RVQLSLNEKM- -QIRHMAIESTRLAANKTL-EKTTGET-GYYSRLRIYPHILLRENKQIA-TAGADRISEG MRRSWGKATSLGARVKH-GQCIMELYV---NGNDHLEAAKKALKGACVKL--AGTPSI-- ---------------------T-----VLEWNKPSP------------------------ ------------------------------------------------------------ -----------------------------M-PAT-NVLANLFVTLYNNETRRKDKCIVLP TSKIGVEVLKTLQKGGYVGEFEHIDDKR-GGKFKINL----------------------L AKITKCGAISPRFKVKNDEFNSWEQ--------------------QYLPAYNRGMLLVTT NQGVMSHHEAVEKGIGGFLIGYVY------------------------------------ MSTKQL---------EKFQDEVIIPEGVKVTQNKH-----MLGFE--GPLGKTFKSFR-- ----KIPINIEI-TESK-IILK---TT-GFR---KRDYSILHTARSIIRNICEGLVEG-Y TIKMKIVFAHFPVTVKVD---GKK--IL-IENFQGERAPRITKIV--GNTKVIPKGE--- ----DVILTGEVWTDITQTAANIEQKTKVKN---KDHRV----------FLDGIYVYDTK KGIEK------------------------------------------------------- ------------------MG-------ARKHHQPRRGSLAYSPRGRAKSMEARIRAW-P- K-LDSD---EPRILAHCGFKAGCVQIVSIDDREKTPNA--GKQLVSLGTVLVTPPLLILG IRGYSKD--HYG-LH---AEFDVYAEDIPKY-----I-----TKEI-------------T L---------KNK--------EGA-----------------------LEHAEKR------ ---LG--KIKEIFAIVAVSP-----RAAGLEQKKPYVFEALVSGGNIQ---KQFTHVKEL LGK-EIKIDQIFELGSTVDVAAITKGKGWQGVIQRWGVKKKQH--KSRKTVRE--VGSL- GPIS-PQSVM-YTVPRAGQMGFHQRTEYDKRIMIIGN--TDNDQIKINPDGGYKHFGLVK GDFIVLKGSVPGTYRRLIKLRSQIR-----N-VPAK-VLKP-NILEVVV----------- ------------------------------------------------------------ ----MGRFGYAFQ---------------------------------------NYDATRHV R----------------------------------------------------------- -----------SSLREKD-ISHKHAREVAVAI--KGMSIEKARDYLQAVIHKDRAVAFRR FKN-QVGHKS-----D---PGMMS-GRYPQKTAKEFIKVLDNLESNAEYKGM-DLDRLKI INATVHKGVTIKRFIP-------RAMGR--ATPKNDVL-THVELIA-------QEI---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGKRPLVRR-------------RGRGGHQFRSTSTGKVG SKANY-----PRFPLSEQHEGE----IIDLIHERGREAPLSKIRFEDGSV-SFVPAVLGT KVGITLQFGL-------------KSK---IEKGNVISVQNIPDGTTVCNIERHFGDGGAI VKSAGTDATIFSH-GD--E-GVTIKLPSGKFTTLNPKNRAMIGTLAGGGAGERPLMSAGN TWRSFRSKGKKFPIVRGVAQAAYVHPHG-GGRHQHV---G-Q----SSTVSRNAPPGAKV GSIAARKTG---------RARIKERR---------------------------------- -------------------------------MSQT-----------------IESPMKKI SIDKIVLNMGVGKSGDEIEIAKRALDQI-TGK-KSCSRNAK--E--TQRDWGIRKGEPIG VSVTVRGE-DA-ITLLKRLLDAKGDIVKGKSFDNFGNYSFGINEHIDIPGVKYEPQIGIL GLGISIALTRP-GYGIRKRSKHKASVGKSHIITSQEAKDYLVKEFGVTI-E--------- --- >Bin115_genes ----------------------------MGWGQVGQHR-KSGGRGGKGR-AGGRKHFWIR TVK-----YEPE-------------------------RY------------LHKGFLPPS AKVP--KI--KT-----I-NVGELVE---LAAAVLTD-YG---IK---------GGN--E LD--LTSLG--IGKIL----GRGKIAVPL-NIKV---AKISASAQEKIEEAGG--SII-- --------------------------EP-------------------------------- ---------------------------------------------------------MSI V--------------------RKIIKNNIERLKV----------------DELLAKEY-E QAGYGGITLT------KTPMGAQINLYAMRPGRVIGKRGRAIKAASERLETELGLPNPQI TVI-EVEVPELNPAIM----------ASRIANALER--GVHFRRSIFWSLRRIMDSGALG CEIILKGP-L------------RS-------------ARSRFEKVV-------------- ----EGYVPKSGEPALRNVKIATIHVKMKRGTLG-------------------------- ----------VTVKIV---------------PPDA----------KFPDKI--------- ------------------------S-LDGLPDI----------EYQLP-MEEAAPV---- ------------------------------------------------------------ ----------AEAP-----------AEAVVD-ETIK------------------------ ---------------------AVEPEADAAEPVIT------------DEAA-TEEAPVV- -EETP------------------------------------------------------- ------------VEEAAVEPAVEEAVV-------EKS-------------VTEE------ -AA-VEEPIEAVEPEA-------------------------------------------- ------------------------------------------------------------ ----------------------------------------------MKVPVINLQNEKIG EIEVPKVFST-PVRHDVIKKAVIALQSTRFQPQGRDPMAGKHTTAESRGTGH-------- ----GIARVPR-LKG------GSRAAFGVSIVGGHAAFPPV-----SWKVIVKRINKKEK RFAIRSGIAATAVKELVEKRGHKFE--S--EHLPIVVSNEIQSLKKTKDVEALF---IAI GVQDDVERA-DR-RKVRAGRGKMRGRKHKKGKGPLIV-V-A-EDDG-------------- -----IGYAARNLPGVEICSVAGLNAELLAPGAHPGRLVIWTESA---FGQVDD--VWER ------------------------------------------------------------ ---------------------------------------------MAKGPR---YRTPYR RRRQKKTDYAARRVLA-TSEHPRLVVRISNKTIQIQLTRSEIVGDFVLVKASSHELKAEH GW----IASGKNMPAAYLIGYLAGKKAIAA-GYKYANLDVGLKRVTSGNKIFAVVQGVND AGFEVPF--DSDIAPS------PEAISGQVIADYAKNIEDPFE--YERRFSVYLR--RGL RPEALPSHFEEVKKRI------------EENNDE-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??????????????????????????????????????---------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------MPKDFNYRGKTVE--------------------ELKAMSMDEFIQLL PSRMRRSLRRGL------SAEQRIVLEKLR--RNKG---------KPVRTH-ARDLI--- ------ILPDM----------------------------LGKTVFCYTG--------RDF R-----------EILINQKMLGHY----------------------------LGE----- ----------YASPM-AIVRHGR------------------------------------- -------------PGIGA-SR-------------------------------SSMYIPLK ------------------------------------------------------------ ----------------------------------------------------------M- ------------ARRARIKLTSTDAVKLQDVCDEIKNIAKRIGVKLVGPIPLPTKKLVVP TRKTPCGDGS-------NTWDRFEMRVHKRLIEI-DARDRVMRSIMRIRVPNEVYIEMEI R-----------------------------------------------------MRTSLY AVKV--TNGQERTVALMLSDKAKVEDLSIQAILAPSELKGYVIIEAQTPHIVDELIRGMR HTRERVQGTISPDEVDHYIETKAV-VEGLDEGTLVEVIAG--PFK--GMQARIVRVDSSK EEVTIEILEA-------AFTLP--------ITVHADYVRELKGAQY-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------???????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ????????????------------------------------------------------ ---------------------------MPRVRSPKRGSRGYSPRKRARNPKGRVSYW-P- K-LEG----EPQLAGFAGYKAGMTHLFYIEDRQRVPEY--GQEVKAAATVIDTPPMLVVA IRAYRKD--YDG-LH---AITEAWMQNQPRD-----L-----HRRI-------------- ----TFA---TDP------QPESK-----------------------LNEIAEK------ ---IN--KVAEIRVIAATQP-----RLSSLSQKAPDLFEIPVSGGSME---SQLKYAKGL LGK-TVTVKDVFGPSEGIDIIGVTKGKGFQGPVKRWGIRILAR--KARKSRRA--VASI- GPWV-PRRVM-PQVPRAGQMGFHNRTEFNKRILLMNG---DTD--RINPKAGFKNYGFVK GDYLLLKGSIIGSAKRLIKLRKTVR-----D-TDYP-EEAP-QITYLHTEWTKGGIQQ-- ------------------------------------------------------------ ----MPSWKYSVQ---------------------------------------GLDPDKTA I----------------------------------------------------------- -----------ASGRDLR-IKPKTSREICNTL--KGMKLDEAKTFLNDVIDRKRAVPYYR YRG-KTPHRK-----GLN--GHDA-GRYPEKAAGEILKILDSVEANAEFKGL-YADRLRI VHMAAHKARVIRKYIP-------RAFGR--ASPYYKHL-THIEVAV-------EEY---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MNKK- APSKYP-VIT-----EEGQQGF----VKSMEHEPGRGAPLAYIEFGPGNG-YHVAATEGI SLNMPIMVGV-------------GAI---PKVGNVLHLKDIPEGTMVSNVELRPGDGGKI ARSSGAFATVIAH-ID--P-YSTIRLPSRRIIRVKSNSRATIGIVSGGGRLERPFMKAGE KHHKKKAKGHKYPTAHGVKMPAAMHPHG-GGRHRRP---G-K----STTVSRHAPPGAKV GLIAARNSG-------RRQRTRRN-------------------------??????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ??? >GCA_007116655 -------------MTKNTI-LQSII-------------------------RDLEVLSKKE K---------VAIWKR------------------------V----------AA-DLQKPT RAKR------------EV-NVAKLAQY----------------AK---------DSETML VP----------GKIL----GTGQIDIPI-SVVG---YAISDAAKAKIIAAKG--TCK-T IEEEMKK------------------------NPKGSKLRIIG------------------ ----------------------------------------------------------MI E--------------------RKIVDEKLQEYLI----------------EEFVRETL-N RVGHSKTELQ------KTPVGEKIIIHASRPGLIVGSKGSNIKKLTKVLKTKFKLENPVI EIA-EIQKPELDAHLV----------AENIAFLLERFGSQRFKGVGYSAMESAMKSGAKG IEILISGK-L------------PA-------------DRARTWRFY-------------- ----MGYLKKFGDLAINGVDTSYIQAKLKTGVIG-------------------------- ----------IQVRIM---------------PPDL----------VLPDAV--------- ------------------------T-L------------L-QTEVGD--VE--------- -------------------------EGPTQK----------------------------- --------DEKEAK-----------EQAEEVA---------------------------- ---------------------------KEVKD----------------VVDKDSSQEVAE -ESKSK------------------------------------------------------ ------------PVKKVAKKTTKK------------------------------------ ---VAKKATKSTSDSTKSE----------------------------------------- ------------------------------------------DAK--------------- ----------------------------------------------MKIKIIDVQNSEKG TVELPSQFLE-PVRLDLIKRAVLAIQSNSRQAYGASPEAGKRHSADVSRRRR-K---YRG SYGKGISRVPRKILSRNGSQIHWVGAVAPGTVGGRRAHPPK-----AEKQWDIKINDTER RKAIRSALSATIDPQLVSARGHVLP--K---SYPFILSNDFEDISKTKDFHVAL---QSV GFTEELERSQN--KNVRAGKGTMRGRRYKRSVGPLIV-V-S-DTCK-------------- -----ASKSARNIPGVEVVSVSNVNVEKLAPGTQAGRVTLYTQSA---IEKLKESKLFE- ------------------------------------------------------------ -----------------------------------------??????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????------------------MKGI-KASVTRALPIGAQMQTCDNSGA KVVEIIGVKG--AKTRKGRLAAAGVGDMVMVSVVSGRPDMRNK---VVPAVVVRQKKEYK RPDGMRVKFEDNSVVVLKDEK-GNPKGTIFKGPIAKEAVE-RWGAVGKVANIVL------ ----------------------MTTKKSIG---YD-VPT-PK-I---------------- -EGET-DKNCPF------------------TSSLRVRGTISKGTVVSDSAPLTATVQIER QIFIPKYKRYKKKYSKIRVHNPASIN--AKVGDIVEFIGCRPLSKTKSAVIVRI------ ----------VQ---------------------------------------------EKS E----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MAKKIFRFRGMTLE--------------------ELQKLSLNDLLPFL TADVRRKVKRGF------TEQEQKFMAKLEKKSG-------------VKTH-CRDMV--- ------ILPSM----------------------------VSKTVKLARG--------NSF D-----------DIVIQPEMIGHR----------------------------LGE----- ----------FVFTR-KRVTHGS------------------------------------- -------------AGVGA-SR-------------------------------SSANQSKK ------------------------------------------------------------ ------------------------------------------------------------ ------------MPKARIKLVSTDIDKINTVCDFIRGIAEKTGVDVRGPIPLPTKKLRVT TRKSPCGDGK-------ATWERYEMRIHKRLIDM-GIDERALRMVMRVEIPKGLNIEIEM VD---------------------------------------------------------- -MTTQ-LYNQN-----WKKSAQPRKQRKYAYN-APVHIRGSF-LHAPLSADLKKKY---- ---------------------AKN-AVRVRKGDKVKVMVG--QFK--GKIGVVDKIDITT AKVYVQKVEGIKKDGS-KYLYP----------IHASNVQILDLKLG-------------- ---------DKK-RE-----------------------------------ALLKRGQK-- -----ND----------------------------------------------------- ------------------------------------------------------------ ----------------???????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????----------------- -----------------------------M-VLN-DPLATMLSKIQNANRVNKTEVIIKP VSKFMIIVLELLQKHGYIKEFEVVEDGR-GNHIKIKG----------------------F EQINGCGAIKPRFSFTVSDAVLVEQ--------------------EYLPAKGFGIIIVTT SKGLMTIDKAQEEKVGGKLVAYCY------------------------------------ MKIDLY------------EEKIPILEGVTVTCDKG-----VVTAK--GPFGETSKKLL-N S-K----IHITT-DGSF-VVLT---AK-KAT---RKEKMFINTFRAHINNVMKGAKEG-F EYELRICSGHFPMSASVK---GSV--FE-LKNFLGENTPRKLELK--AGAKVSIEGE--- ----IIKVQASNKELAGQVAADLEQLTRITD---FDRRI----------FQDGIFIIKKA GKSMLA------------------------------------------------------ ---------------------------MGKARSPRHGSMQFWPRVRAQSETPRIRSW--- --GK---A-DSGVLGFAGYKAGMTRIQYVDPVKTSLTK--GQVVSEAVTIIECPPLSVIA FRCYTKT--SDNQLV---VSHQINASKVGLE-----V-----KRRL-------------- ----SQS---V-------KESQQN-----------------------ADSID-------- ---ES--AVHSVRVVVATQP-----KLTGFGKKTADIFELALGGDV-S---SQLAFAKEK LGQ-IITVADVFKPGELVDAHAVTKGKGYQGSVKRFGVSLRQH--KSEKAKRG--PGSL- GPWKGQGHVM-YRVAMAGKMGYHLRTDYNKRVELISD---DVS--KVNPVSGISQYGLVK GSYILVRGSVSGPKKRLVTLTKAIR---P-N-AKYDFGEL--TLDYISIDAQN------- ------------------------------------------------------------ -----MAYKYATQ-----------------------------------------TTEKMA K----------------------------------------------------------- -----------AVILSQA-VSTKQSIEVASFI--RGRSTKQALELLSQVAQTQRAVPYKR FTN-GAGHKP-----G-----IGP-GKFPLKTIGVFEKAVKLAIANATDKSM-DVDSLKI ASVVVNRGPNTPRY------------GR--IRGRTAKV-THIEIVV-------EEVEATQ ----KKRPKKQQKEVTQTKVKV-------------------ESKSQEPSSKSKEIQ---- -------------KTQSKSETV---V-------KADEKP--------------------- --------------------------------AEVKAESTS--------QKPE----VEE ------------------KKQ--------------------------------------- ---------------------MGKRIIAQR-------------RGAGTSRYRAHSFKFK- GKASH-----PAISDA-IKQGI----ITDLVSCAAHTAPLAQIQFDDGDV-SYMLACEGM IVGEQVQIGS-------------QAA---AQEGNVLPLQEIPEGTLVYNVEAQPGDGGKF VRASGVFARVVSK-TN--T-GVVLRLPSKTTKTFHYQCRAAIGVLAGGGRVDKPLLKAGV AHFKHKARNHLYPKVSASAMNAVDHPYG-NKRTSRK---S-K----AMPVSRHAPPGRKV GMIAARRTG-------RKKK---------------------------------------- -------------------------------MSET------------------KHIMQEL QIEKVTLNCGCGVDHALLDKSVKLLESI-TNK-TAVRTKSK--V--RLASWGLRKGLPIG AKVTIRGQ-DA-HALVKRLVEAKEFQLKPTSFDSRGNVSFGISECIDIPGVEYTPDIGII GLQVTITFTKP-GTRVKNRKYRPSHIPARHLVQRDEAIEYMAKNFGVSL-IQKEDEEDEE --- >Bin647_genes ----------MRTTKAKKN-TQQLI-------------------------VALEKQGKKS G---------KNVWKS------------------------V----------AK-RLAKPS RNRA------------RV-NVDKLNKL----------------AKK-------QKDKIFV VP----------GKVL----SMGEVEEKI-NVAC---LDCSKRARDKIEKQKG--KVI-L LKDLIEA------------------------KPKESTMVIVQ------------------ -----------------------------------------------------------M K--------------------LGFDE--IRLINAL---------------DSIARVSA-K DCFIEENTVV-------------YLVPNNTIRQVIGKNGSIIEKMKKKIGKHIELFEYST KPE-EFFSKAFYKASLE---------------------GIEIKKMKQKQVA-IVKTDSTN KKVILKNL-----------------------------RR--LNKIK-------------- ------------------------------------------------------------ ---------ELAKRNY-------------------------------------------- ------------------------G-I--------------------------------- ------------------------------------------------------------ ----------EEVRIR-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????-----------------MMKAI-SASMVRSLGFGSRCICADNSGA KEVRIIAVYK--YHGRKGTHPKGGVGDMVNVVVKKGKPEIRKK---VEKAVIIRAKKEYR RPDGTRVKFEDNAVVLVDDK--GLPKGSEVKGVVAKEVGE-RFPKIAGISAGVAMINTSE ----------------------------------------KKEK----------QE---- ------------------------------STGFSVRGSIFTGKVISTRAPKTVTVERKT IRHIPKYERYKKSKSKIKAHLPENIE--IKEGDIVKIGETRKISKTKSFVVLEV------ ----------I-------------------------------------------KKGEQ- --------------------------------------?????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????----------------------------------------------------- -MKV--------------TSSKPKKQRKWHYS-KPLHLIQKE-FSVHLSKDLRKSV---- ---------------------GKR-SLEVRKGDTVKVLRG--SEKYVGKQGKITSVLRQK RQVLIEGIIRKRTDGT-EIPIP----------FRSSNLMLVTMEEK-------------- ---------DDR-RVKG---------------------------------KKVKK----- ------------------------------------------------------------ --------EEKVTKDGK------------------------------------------- ----------------???????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????----------------- -----------------------------M-SRN-DPIADALINLKNNENASKKECSIRP ASKLLKEILKILQEKGYIGTFEFIDDGR-EGIFKVEL----------------------L GKINECRAIKPRYAVKKTDFEKFEK--------------------RYLPSYDIGTLIVST PKGVTTHNKAKEMQTGGRLLAYIY------------------------------------ -MVEKQ------------VEVIEIPEGVQVELSGN-----DIKVS--ANGKENSRHFK-S T-N----AILKK-VDSK-IEVW---ST-SER---KNVVAECKTVGSHIKNLMHGLQNE-F VYKLEIVYSHFPMNVTVK---DKV--VE-INNLGGAKHPRKAKITG-Q-TKVKVEGK--- ----NITVTGQNKEDAGQTAANMEQATKIKG---KDIRV----------YTDGIYITEKA KTA---------???????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ???????????????????????????????????????????????????????????? ?????????????????????????????????????????????????----------- ----MAENK-----------------------------------------------MKEI KIEKVTVNMGIGKTGDELKKATLILKQV-TGA-KPTETKCK--V--KQPDWGLRLGLTIG AKVTLRGE-KA-GEFLTDAFIAKDKTIKKKNFDKRGNFGFGIKEYIDLPKAKYDPKLGIR GMDVLVTLERP-GYRIKRRKVAKAKVFHSHLISQDEAIGFIKQKFGVEV-V--------- ---