PFAM_key,PFAM,PFAM_desc,Total Number,Smina Failures,Machine Learning Failures ,Machine Learning Failures (RMSD+CS)
PF09160,FimH_man-bind,"FimH, mannose binding",23,0,0,0
PF00665,rve,Integrase core domain,50,20,16,5
PF04253,TFR_dimer,Transferrin receptor-like dimerisation domain,49,13,17,1
PF00104,Hormone_recep,Ligand-binding domain of nuclear hormone receptor,364,49,49,14
PF00135,COesterase,Carboxylesterase family,81,34,34,18
PF00232,Glyco_hydro_1,Glycosyl hydrolase family 1,47,11,2,1
PF00069,Pkinase,Protein kinase domain,1243,388,191,36
PF02785,Biotin_carb_C,Biotin carboxylase C-terminal domain,17,4,1,1
PF00067,p450,Cytochrome P450,1,0,0,0
PF01323,DSBA,DSBA-like thioredoxin domain,6,2,0,0
PF02263,GBP,"Guanylate-binding protein, N-terminal domain",2,0,0,0
PF03414,Glyco_transf_6,Glycosyltransferase family 6,15,2,1,0
PF00433,Pkinase_C,Protein kinase C terminal domain,33,6,2,0
PF01006,HCV_NS4a,Hepatitis C virus non-structural protein NS4a,17,5,6,0
PF13688,Reprolysin_5,Metallo-peptidase family M12,17,4,4,0
PF00026,Asp,Eukaryotic aspartyl protease,461,89,65,5
PF00775,Dioxygenase_C,Dioxygenase,17,4,6,0
PF09273,Rubis-subs-bind,Rubisco LSMT substrate-binding,6,0,1,0
PF00343,Phosphorylase,Carbohydrate phosphorylase,104,27,26,8
PF02984,Cyclin_C,"Cyclin, C-terminal domain",68,33,12,2
PF00233,PDEase_I,3'5'-cyclic nucleotide phosphodiesterase,204,83,51,20
PF00864,P2X_receptor,ATP P2X receptor,3,1,0,0
PF17432,DUF3458_C,Domain of unknown function (DUF3458_C) ARM repeats,34,6,4,1
PF00650,CRAL_TRIO,CRAL/TRIO domain,5,2,1,0
PF05409,Peptidase_C30,Coronavirus  endopeptidase C30,36,8,10,0
PF00089,Trypsin,Trypsin,528,91,66,13
PF00561,Abhydrolase_1,alpha/beta hydrolase fold,102,42,36,12
PF00102,Y_phosphatase,Protein-tyrosine phosphatase,115,19,13,3
PF00303,Thymidylat_synt,Thymidylate synthase,39,14,8,4
PF07654,C1-set,Immunoglobulin C1-set domain,208,50,43,8
PF00074,RnaseA,Pancreatic ribonuclease,52,27,13,1
PF00653,BIR,Inhibitor of Apoptosis domain,65,6,3,0
PF13499,EF-hand_7,EF-hand domain pair,35,7,4,1
PF00953,Glycos_transf_4,Glycosyl transferase family 4,1,0,0,0
PF00194,Carb_anhydrase,Eukaryotic-type carbonic anhydrase,397,176,58,8
PF11602,NTPase_P4,ATPase P4 of dsRNA bacteriophage phi-12,2,1,0,0
PF00595,PDZ,PDZ domain (Also known as DHR or GLGF),44,15,3,0
PF00656,Peptidase_C14,Caspase domain,57,18,11,2
PF00204,DNA_gyraseB,DNA gyrase B,6,3,2,0
PF13649,Methyltransf_25,Methyltransferase domain,11,4,3,1
PF00496,SBP_bac_5,"Bacterial extracellular solute-binding proteins, family 5 Middle",50,5,3,1
PF00168,C2,C2 domain,4,2,1,1
PF13640,2OG-FeII_Oxy_3,2OG-Fe(II) oxygenase superfamily,14,4,5,0
PF00439,Bromodomain,Bromodomain,313,153,81,22
PF00413,Peptidase_M10,Matrixin,146,48,31,5
PF00497,SBP_bac_3,"Bacterial extracellular solute-binding proteins, family 3",41,5,7,0
PF00183,HSP90,Hsp90 protein,170,34,42,19
PF14497,GST_C_3,"Glutathione S-transferase, C-terminal domain",36,19,14,2
PF15009,TMEM173,Transmembrane protein 173,13,6,5,3
PF00271,Helicase_C,Helicase conserved C-terminal domain,5,2,1,0
PF02743,dCache_1,Cache domain,3,0,0,0
PF00509,Hemagglutinin,Haemagglutinin,19,13,0,0
PF06325,PrmA,Ribosomal protein L11 methyltransferase (PrmA),3,1,0,0
PF07714,Pkinase_Tyr,Protein tyrosine kinase,728,155,54,7
PF13561,adh_short_C2,Enoyl-(Acyl carrier protein) reductase,37,23,19,6
PF06815,RVT_connect,Reverse transcriptase connection domain,72,9,12,7
PF01288,HPPK,"7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)",31,15,6,2
PF00856,SET,SET domain,37,9,4,0
PF00077,RVP,Retroviral aspartyl protease,407,47,29,3
PF00063,Myosin_head,Myosin head (motor domain),6,1,2,0
PF01401,Peptidase_M2,Angiotensin-converting enzyme,30,8,0,0
PF00842,Ala_racemase_C,"Alanine racemase, C-terminal domain",1,0,0,0
PF01742,Peptidase_M27,Clostridial neurotoxin zinc protease,21,6,3,1
PF00144,Beta-lactamase,Beta-lactamase,88,38,22,4
PF04095,NAPRTase,Nicotinate phosphoribosyltransferase (NAPRTase) family,29,4,9,2
PF00407,Bet_v_1,Pathogenesis-related protein Bet v I family,6,2,1,1
PF03480,DctP,"Bacterial extracellular solute-binding protein, family 7",9,1,1,0
PF03795,YCII,YCII-related domain,1,1,0,0
PF00998,RdRP_3,Viral RNA dependent RNA polymerase,106,23,12,5
PF01712,dNK,Deoxynucleoside kinase,19,7,4,0
PF00644,PARP,Poly(ADP-ribose) polymerase catalytic domain,153,27,11,1
PF00628,PHD,PHD-finger,17,5,3,0
PF05351,GMP_PDE_delta,"GMP-PDE, delta subunit",17,1,5,1
PF01327,Pep_deformylase,Polypeptide deformylase,41,7,9,0
PF03246,Pneumo_ncap,Pneumovirus nucleocapsid protein,3,1,0,0
PF01234,NNMT_PNMT_TEMT,NNMT/PNMT/TEMT family,28,7,5,4
PF00275,EPSP_synthase,EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase),19,5,3,1
PF01728,FtsJ,FtsJ-like methyltransferase,8,0,1,0
PF07555,NAGidase,beta-N-acetylglucosaminidase,29,1,1,0
PF01048,PNP_UDP_1,Phosphorylase superfamily,68,15,5,0
PF13416,SBP_bac_8,Bacterial extracellular solute-binding protein,31,3,2,0
PF09334,tRNA-synt_1g,tRNA synthetases class I (M),32,10,6,1
PF00139,Lectin_legB,Legume lectin domain,13,8,1,0
PF01729,QRPTase_C,"Quinolinate phosphoribosyl transferase, C-terminal domain",5,3,1,0
PF01382,Avidin,Avidin family,57,9,5,1
PF04069,OpuAC,Substrate binding domain of ABC-type glycine betaine transport system,15,1,1,0
PF00440,TetR_N,"Bacterial regulatory proteins, tetR family",35,9,11,5
PF00120,Gln-synt_C,"Glutamine synthetase, catalytic domain",5,3,2,1
PF04335,VirB8,VirB8 protein,4,2,1,1
PF02774,Semialdhyde_dhC,"Semialdehyde dehydrogenase, dimerisation domain",3,1,0,0
PF00959,Phage_lysozyme,Phage lysozyme,40,5,6,2
PF02590,SPOUT_MTase,Predicted SPOUT methyltransferase,1,0,0,0
PF13354,Beta-lactamase2,Beta-lactamase enzyme family,50,24,12,5
PF00316,FBPase,"Fructose-1-6-bisphosphatase, N-terminal domain",19,5,8,2
PF00576,Transthyretin,HIUase/Transthyretin family,62,33,28,15
PF02569,Pantoate_ligase,Pantoate-beta-alanine ligase,32,11,9,2
PF08123,DOT1,Histone methylation protein DOT1,16,2,1,0
PF00075,RNase_H,RNase H,8,3,4,0
PF10613,Lig_chan-Glu_bd,Ligated ion channel L-glutamate- and glycine-binding site,136,16,8,0
PF03129,HGTP_anticodon,Anticodon binding domain,13,3,1,0
PF04699,P16-Arc,ARP2/3 complex 16 kDa subunit (p16-Arc),4,0,0,0
PF00432,Prenyltrans,Prenyltransferase and squalene oxidase repeat,43,10,9,1
PF00491,Arginase,Arginase family,45,14,13,2
PF07091,FmrO,Ribosomal RNA methyltransferase (FmrO),2,0,0,0
PF00348,polyprenyl_synt,Polyprenyl synthetase,73,26,17,3
PF02780,Transketolase_C,"Transketolase, C-terminal domain",11,0,0,0
PF07468,Agglutinin,Agglutinin domain,1,0,0,0
PF01596,Methyltransf_3,O-methyltransferase,33,6,2,0
PF00735,Septin,Septin,4,2,2,0
PF00454,PI3_PI4_kinase,Phosphatidylinositol 3- and 4-kinase,94,34,8,1
PF01223,Endonuclease_NS,DNA/RNA non-specific endonuclease,16,6,4,1
PF00161,RIP,Ribosome inactivating protein,28,9,4,1
PF02982,Scytalone_dh,Scytalone dehydratase,7,0,4,0
PF00201,UDPGT,UDP-glucoronosyl and UDP-glucosyl transferase,1,0,0,0
PF00112,Peptidase_C1,Papain family cysteine protease,97,33,12,2
PF01094,ANF_receptor,Receptor family ligand binding region,10,0,0,0
PF00215,OMPdecase,Orotidine 5'-phosphate decarboxylase / HUMPS family,40,11,2,0
PF02223,Thymidylate_kin,Thymidylate kinase,27,4,3,1
PF00400,WD40,"WD domain, G-beta repeat",65,14,7,0
PF00716,Peptidase_S21,Assemblin (Peptidase family S21),6,1,1,0
PF01510,Amidase_2,N-acetylmuramoyl-L-alanine amidase,11,0,0,0
PF00274,Glycolytic,Fructose-bisphosphate aldolase class-I,4,3,3,1
PF00443,UCH,Ubiquitin carboxyl-terminal hydrolase,10,0,1,0
PF00171,Aldedh,Aldehyde dehydrogenase family,13,3,1,0
PF00386,C1q,C1q domain,1,0,0,0
PF01564,Spermine_synth,Spermine/spermidine synthase domain,12,3,6,5
PF00850,Hist_deacetyl,Histone deacetylase domain,54,16,10,1
PF00300,His_Phos_1,Histidine phosphatase superfamily (branch 1),8,2,2,1
PF02518,HATPase_c,"Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase",53,17,6,2
PF00337,Gal-bind_lectin,Galactoside-binding lectin,39,17,7,0
PF01532,Glyco_hydro_47,Glycosyl hydrolase family 47,9,6,3,0
PF08832,SRC-1,Steroid receptor coactivator,10,1,1,1
PF00180,Iso_dh,Isocitrate/isopropylmalate dehydrogenase,2,1,0,0
PF12680,SnoaL_2,SnoaL-like domain,7,1,2,1
PF03143,GTP_EFTU_D3,Elongation factor Tu C-terminal domain,3,1,0,0
PF00680,RdRP_1,RNA dependent RNA polymerase,8,1,0,0
PF00061,Lipocalin,Lipocalin / cytosolic fatty-acid binding protein family,105,40,45,14
PF17450,Melibiase_2_C,Alpha galactosidase A C-terminal beta sandwich domain,6,0,0,0
PF01227,GTP_cyclohydroI,GTP cyclohydrolase I,1,0,0,0
PF00209,SNF,Sodium:neurotransmitter symporter family,29,3,4,2
PF16454,PI3K_P85_iSH2,Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain,15,2,0,0
PF13545,HTH_Crp_2,Crp-like helix-turn-helix domain,2,0,1,0
PF02201,SWIB,SWIB/MDM2 domain,69,10,7,0
PF02801,Ketoacyl-synt_C,"Beta-ketoacyl synthase, C-terminal domain",17,14,8,1
PF00857,Isochorismatase,Isochorismatase family,1,0,0,0
PF01255,Prenyltransf,Putative undecaprenyl diphosphate synthase,21,4,3,1
PF02868,Peptidase_M4_C,"Thermolysin metallopeptidase, alpha-helical domain",34,8,6,0
PF14670,FXa_inhibition,Coagulation Factor Xa inhibitory site,114,12,4,0
PF08211,dCMP_cyt_deam_2,Cytidine and deoxycytidylate deaminase zinc-binding region,3,0,1,0
PF02768,DNA_pol3_beta_3,"DNA polymerase III beta subunit, C-terminal domain",27,5,3,1
PF02237,BPL_C,Biotin protein ligase C terminal domain,12,1,1,0
PF03328,HpcH_HpaI,HpcH/HpaI aldolase/citrate lyase family,3,1,1,1
PF02991,Atg8,Autophagy protein Atg8 ubiquitin like,4,0,0,0
PF07971,Glyco_hydro_92,Glycosyl hydrolase family 92,4,2,1,0
PF08411,Exonuc_X-T_C,Exonuclease C-terminal,3,1,1,1
PF00246,Peptidase_M14,Zinc carboxypeptidase,43,3,8,2
PF00156,Pribosyltran,Phosphoribosyl transferase domain,39,13,7,0
PF03571,Peptidase_M49,Peptidase family M49,4,1,0,0
PF00625,Guanylate_kin,Guanylate kinase,3,1,1,0
PF00557,Peptidase_M24,Metallopeptidase family M24,74,26,14,1
PF01547,SBP_bac_1,Bacterial extracellular solute-binding protein,9,2,0,0
PF01179,Cu_amine_oxid,"Copper amine oxidase, enzyme domain",6,2,1,1
PF00186,DHFR_1,Dihydrofolate reductase,28,14,6,0
PF00254,FKBP_C,FKBP-type peptidyl-prolyl cis-trans isomerase,41,7,3,1
PF01204,Trehalase,Trehalase,4,0,1,0
PF00326,Peptidase_S9,Prolyl oligopeptidase family,93,16,5,0
PF00273,Serum_albumin,Serum albumin family,14,5,1,0
PF01661,Macro,Macro domain,11,2,2,1
PF03352,Adenine_glyco,Methyladenine glycosylase,3,1,1,0
PF16899,Cyclin_C_2,Cyclin C-terminal domain,21,3,0,0
PF03284,PHZA_PHZB,Phenazine biosynthesis protein A/B,4,1,0,0
PF03720,UDPG_MGDP_dh_C,"UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain",1,0,0,0
PF00064,Neur,Neuraminidase,56,13,5,2
PF00503,G-alpha,G-protein alpha subunit,9,2,2,1
PF00179,UQ_con,Ubiquitin-conjugating enzyme,6,5,4,1
PF07479,NAD_Gly3P_dh_C,NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus,2,0,0,0
PF00185,OTCace,"Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain",4,0,0,0
PF00659,POLO_box,POLO box duplicated region,23,5,6,0
PF00676,E1_dh,Dehydrogenase E1 component,1,0,0,0
PF14681,UPRTase,Uracil phosphoribosyltransferase,2,0,0,0
PF02089,Palm_thioest,Palmitoyl protein thioesterase,1,0,0,0
PF00905,Transpeptidase,Penicillin binding protein transpeptidase domain,29,12,10,2
PF00728,Glyco_hydro_20,"Glycosyl hydrolase family 20, catalytic domain",27,9,1,0
PF02179,BAG,BAG domain,15,9,1,0
PF01702,TGT,Queuine tRNA-ribosyltransferase,36,3,3,0
PF02211,NHase_beta,Nitrile hydratase beta subunit,4,1,0,0
PF02098,His_binding,Tick histamine binding protein,3,1,0,0
PF05350,GSK-3_bind,Glycogen synthase kinase-3 binding,4,2,0,0
PF00244,14/03/2003,14-3-3 protein,42,8,1,0
PF00753,Lactamase_B,Metallo-beta-lactamase superfamily,51,22,25,13
PF00423,HN,Haemagglutinin-neuraminidase,5,2,0,0
PF01039,Carboxyl_trans,Carboxyl transferase domain,16,3,2,0
PF07686,V-set,Immunoglobulin V-set domain,36,8,6,1
PF00385,Chromo,Chromo (CHRromatin Organisation MOdifier) domain,24,6,3,2
PF00840,Glyco_hydro_7,Glycosyl hydrolase family 7,5,2,2,0
PF09095,DUF1926,Domain of unknown function (DUF1926),1,1,0,0
PF05063,MT-A70,MT-A70,1,0,0,0
PF00607,Gag_p24,gag gene protein p24 (core nucleocapsid protein),9,0,1,0
PF01979,Amidohydro_1,Amidohydrolase family,8,1,2,1
PF09127,Leuk-A4-hydro_C,"Leukotriene A4 hydrolase, C-terminal",38,16,11,6
PF15901,Sortilin_C,"Sortilin, neurotensin receptor 3, C-terminal",5,0,0,0
PF00121,TIM,Triosephosphate isomerase,22,10,5,0
PF07737,ATLF,"Anthrax toxin lethal factor, N- and C-terminal domain",15,2,2,0
PF00132,Hexapep,Bacterial transferase hexapeptide (six repeats),12,3,1,0
PF07687,M20_dimer,Peptidase dimerisation domain,1,0,0,0
PF00494,SQS_PSY,Squalene/phytoene synthase,25,8,6,1
PF00603,Flu_PA,Influenza RNA-dependent RNA polymerase subunit PA,33,11,9,5
PF00017,SH2,SH2 domain,61,21,19,6
PF02038,ATP1G1_PLM_MAT8,ATP1G1/PLM/MAT8 family,4,2,1,1
PF02097,Filo_VP35,Filoviridae VP35,9,1,1,0
PF13621,Cupin_8,Cupin-like domain,11,1,3,0
PF01451,LMWPc,Low molecular weight phosphotyrosine protein phosphatase,4,0,0,0
PF02373,JmjC,"JmjC domain, hydroxylase",26,17,3,0
PF01476,LysM,LysM domain,1,0,0,0
PF01306,LacY_symp,LacY proton/sugar symporter,1,0,0,0
PF17211,VHL_C,VHL box domain,25,0,0,0
PF08423,Rad51,Rad51,15,12,4,0
PF00591,Glycos_transf_3,"Glycosyl transferase family, a/b domain",15,9,4,1
PF09009,Exotox-A_cataly,Exotoxin A catalytic,6,2,0,0
PF00754,F5_F8_type_C,F5/8 type C domain,5,1,1,0
PF13377,Peripla_BP_3,Periplasmic binding protein-like domain,2,1,1,0
PF03144,GTP_EFTU_D2,Elongation factor Tu domain 2,1,1,0,0
PF00464,SHMT,Serine hydroxymethyltransferase,7,0,4,1
PF07361,Cytochrom_B562,Cytochrome b562,8,3,1,1
PF00870,P53,P53 DNA-binding domain,18,5,2,0
PF00533,BRCT,BRCA1 C Terminus (BRCT) domain,8,0,0,0
PF01753,zf-MYND,MYND finger,13,5,2,0
PF00249,Myb_DNA-binding,Myb-like DNA-binding domain,26,0,1,1
PF02608,Bmp,ABC transporter substrate-binding protein PnrA-like,3,0,0,0
PF14651,Lipocalin_7,Lipocalin / cytosolic fatty-acid binding protein family,2,0,0,0
PF02931,Neur_chan_LBD,Neurotransmitter-gated ion-channel ligand binding domain,65,19,14,3
PF00113,Enolase_C,"Enolase, C-terminal TIM barrel domain",8,1,0,0
PF01187,MIF,Macrophage migration inhibitory factor (MIF),13,1,3,1
PF07748,Glyco_hydro_38C,Glycosyl hydrolases family 38 C-terminal domain,32,0,0,0
PF00134,Cyclin_N,"Cyclin, N-terminal domain",10,7,2,0
PF00793,DAHP_synth_1,DAHP synthetase I family,11,3,2,0
PF02866,Ldh_1_C,"lactate/malate dehydrogenase, alpha/beta C-terminal domain",16,13,7,0
PF00704,Glyco_hydro_18,Glycosyl hydrolases family 18,67,29,6,1
PF09041,Aurora-A_bind,Aurora-A binding,2,0,0,0
PF07938,Fungal_lectin,Fungal fucose-specific lectin,7,4,1,0
PF04057,Rep-A_N,"Replication factor-A protein 1, N-terminal domain",14,7,4,2
PF05761,5_nucleotid,5' nucleotidase family,2,0,0,0
PF01156,IU_nuc_hydro,Inosine-uridine preferring nucleoside hydrolase,10,0,0,0
PF01694,Rhomboid,Rhomboid family,6,3,3,0
PF03308,ArgK,ArgK protein,3,0,0,0
PF07652,Flavi_DEAD,Flavivirus DEAD domain,6,2,1,0
PF05014,Nuc_deoxyrib_tr,Nucleoside 2-deoxyribosyltransferase,6,0,0,0
PF02875,Mur_ligase_C,"Mur ligase family, glutamate ligase domain",14,2,1,0
PF02861,Clp_N,"Clp amino terminal domain, pathogenicity island component",4,1,0,0
PF00903,Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily,14,6,2,0
PF00452,Bcl-2,"Apoptosis regulator proteins, Bcl-2 family",38,4,8,3
PF00293,NUDIX,NUDIX domain,30,7,6,1
PF01636,APH,Phosphotransferase enzyme family,10,5,1,0
PF07562,NCD3G,Nine Cysteines Domain of family 3 GPCR,1,0,0,0
PF00079,Serpin,Serpin (serine protease inhibitor),12,1,1,0
PF01274,Malate_synthase,Malate synthase,5,0,0,0
PF00211,Guanylate_cyc,Adenylate and Guanylate cyclase catalytic domain,16,4,2,1
PF00334,NDK,Nucleoside diphosphate kinase,10,6,6,3
PF07977,FabA,FabA-like domain,21,7,6,5
PF00193,Xlink,Extracellular link domain,7,3,2,1
PF13855,LRR_8,Leucine rich repeat,6,1,0,0
PF02207,zf-UBR,Putative zinc finger in N-recognin (UBR box),8,1,1,0
PF00383,dCMP_cyt_deam_1,Cytidine and deoxycytidylate deaminase zinc-binding region,2,0,0,0
PF00068,Phospholip_A2_1,Phospholipase A2,31,9,10,5
PF00012,HSP70,Hsp70 protein,31,8,4,1
PF00027,cNMP_binding,Cyclic nucleotide-binding domain,11,1,0,0
PF13193,AMP-binding_C,AMP-binding enzyme C-terminal domain,3,0,1,0
PF01150,GDA1_CD39,GDA1/CD39 (nucleoside phosphatase) family,2,1,0,0
PF18781,Phage_spike_2,Phage spike trimer,4,1,0,0
PF00150,Cellulase,Cellulase (glycosyl hydrolase family 5),12,2,0,0
PF16770,RTT107_BRCT_5,Regulator of Ty1 transposition protein 107 BRCT domain,2,2,1,0
PF09180,ProRS-C_1,"Prolyl-tRNA synthetase, C-terminal",5,1,0,0
PF01053,Cys_Met_Meta_PP,Cys/Met metabolism PLP-dependent enzyme,6,2,2,1
PF12950,TaqI_C,TaqI-like C-terminal specificity domain,3,2,2,0
PF00225,Kinesin,Kinesin motor domain,29,0,5,0
PF03306,AAL_decarboxy,Alpha-acetolactate decarboxylase,3,2,0,0
PF12330,Haspin_kinase,Haspin like kinase domain,3,1,0,0
PF00490,ALAD,Delta-aminolevulinic acid dehydratase,7,3,2,0
PF00639,Rotamase,PPIC-type PPIASE domain,28,5,3,0
PF02834,LigT_PEase,LigT like Phosphoesterase,1,0,0,0
PF11616,EZH2_WD-Binding,WD repeat binding protein EZH2,8,2,1,0
PF07702,UTRA,UTRA domain,1,0,0,0
PF14538,Raptor_N,Raptor N-terminal CASPase like domain,2,0,0,0
PF07840,FadR_C,FadR C-terminal domain,1,1,0,0
PF01804,Penicil_amidase,Penicillin amidase,9,2,1,0
PF08360,TetR_C_5,"QacR-like protein, C-terminal region",8,3,4,2
PF00051,Kringle,Kringle domain,10,2,3,0
PF02274,Amidinotransf,Amidinotransferase,4,0,2,0
PF01425,Amidase,Amidase,17,6,7,2
PF00004,AAA,ATPase family associated with various cellular activities (AAA),6,0,2,0
PF00523,Fusion_gly,Fusion glycoprotein F0,5,1,1,1
PF03551,PadR,Transcriptional regulator PadR-like family,3,2,0,0
PF01395,PBP_GOBP,PBP/GOBP family,15,9,6,2
PF00397,WW,WW domain,11,3,2,1
PF13341,RAG2_PHD,RAG2 PHD domain,3,2,2,0
PF00604,Flu_PB2,Influenza RNA-dependent RNA polymerase subunit PB2,12,4,1,0
PF10291,muHD,Muniscin C-terminal mu homology domain,1,1,0,0
PF00821,PEPCK_C,Phosphoenolpyruvate carboxykinase C-terminal P-loop domain,12,5,5,1
PF13088,BNR_2,BNR repeat-like domain,15,4,4,1
PF14598,PAS_11,PAS domain,5,1,0,0
PF01070,FMN_dh,FMN-dependent dehydrogenase,2,1,1,0
PF00076,RRM_1,"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)",3,0,0,0
PF00651,BTB,BTB/POZ domain,16,3,0,0
PF00701,DHDPS,Dihydrodipicolinate synthetase family,8,5,2,1
PF12327,FtsZ_C,"FtsZ family, C-terminal domain",2,0,1,0
PF00809,Pterin_bind,Pterin binding enzyme,30,6,5,1
PF00342,PGI,Phosphoglucose isomerase,4,2,1,0
PF02907,Peptidase_S29,Hepatitis C virus NS3 protease,28,4,2,0
PF09156,Anthrax-tox_M,"Anthrax toxin lethal factor, middle domain",4,2,2,0
PF09396,Thrombin_light,Thrombin light chain,19,4,3,0
PF00578,AhpC-TSA,AhpC/TSA family,1,0,0,0
PF00885,DMRL_synthase,"6,7-dimethyl-8-ribityllumazine synthase",9,2,4,0
PF02827,PKI,cAMP-dependent protein kinase inhibitor,64,18,6,0
PF14509,GH97_C,"Glycosyl-hydrolase 97 C-terminal, oligomerisation",3,0,0,0
PF04545,Sigma70_r4,"Sigma-70, region 4",7,3,2,0
PF00692,dUTPase,dUTPase,17,2,3,0
PF01653,DNA_ligase_aden,NAD-dependent DNA ligase adenylation domain,13,3,1,0
PF00515,TPR_1,Tetratricopeptide repeat,2,0,0,0
PF00265,TK,Thymidine kinase,2,0,1,0
PF02775,TPP_enzyme_C,"Thiamine pyrophosphate enzyme, C-terminal TPP binding domain",11,1,2,1
PF00355,Rieske,Rieske [2Fe-2S] domain,1,0,0,0
PF13385,Laminin_G_3,Concanavalin A-like lectin/glucanases superfamily,3,1,0,0
PF02876,Stap_Strp_tox_C,"Staphylococcal/Streptococcal toxin, beta-grasp domain",2,1,1,0
PF13243,SQHop_cyclase_C,Squalene-hopene cyclase C-terminal domain,14,9,5,3
PF00258,Flavodoxin_1,Flavodoxin,16,0,0,0
PF11598,COMP,Cartilage oligomeric matrix protein,4,3,1,1
PF00291,PALP,Pyridoxal-phosphate dependent enzyme,22,2,1,0
PF00160,Pro_isomerase,Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD,33,5,4,0
PF16317,Glyco_hydro_99,Glycosyl hydrolase family 99,6,4,1,0
PF02557,VanY,D-alanyl-D-alanine carboxypeptidase,1,0,1,0
PF01116,F_bP_aldolase,Fructose-bisphosphate aldolase class-II,11,3,0,0
PF02668,TauD,"Taurine catabolism dioxygenase TauD, TfdA family",7,0,1,0
PF01746,tRNA_m1G_MT,tRNA (Guanine-1)-methyltransferase,4,1,0,0
PF06441,EHN,Epoxide hydrolase N terminus,1,0,0,0
PF00590,TP_methylase,Tetrapyrrole (Corrin/Porphyrin) Methylases,2,0,0,0
PF00962,A_deaminase,Adenosine/AMP deaminase,18,6,3,0
PF16186,Arm_3,Atypical Arm repeat,16,6,4,1
PF13410,GST_C_2,"Glutathione S-transferase, C-terminal domain",2,1,1,0
PF04354,ZipA_C,"ZipA, C-terminal FtsZ-binding domain",2,1,0,0
PF07951,Toxin_R_bind_C,"Clostridium neurotoxin, C-terminal receptor binding",7,1,1,0
PF01376,Enterotoxin_b,Heat-labile enterotoxin beta chain,12,6,3,0
PF13378,MR_MLE_C,Enolase C-terminal domain-like,10,2,3,1
PF08915,tRNA-Thr_ED,Archaea-specific editing domain of threonyl-tRNA synthetase,9,0,1,0
PF01120,Alpha_L_fucos,Alpha-L-fucosidase,22,3,2,0
PF02928,zf-C5HC2,C5HC2 zinc finger,6,4,3,0
PF13288,DXPR_C,DXP reductoisomerase C-terminal domain,20,6,2,0
PF05891,Methyltransf_PK,AdoMet dependent proline di-methyltransferase,5,1,1,0
PF00036,EF-hand_1,EF hand,16,5,4,3
PF06172,Cupin_5,Cupin superfamily (DUF985),1,1,1,0
PF01419,Jacalin,Jacalin-like lectin domain,9,3,0,0
PF00128,Alpha-amylase,"Alpha amylase, catalytic domain",3,0,0,0
PF02142,MGS,MGS-like domain,3,0,1,0
PF04389,Peptidase_M28,Peptidase family M28,24,7,2,1
PF13458,Peripla_BP_6,Periplasmic binding protein,6,0,0,0
PF01365,RYDR_ITPR,RIH domain,2,1,1,1
PF00155,Aminotran_1_2,Aminotransferase class I and II,15,5,1,0
PF10604,Polyketide_cyc2,Polyketide cyclase / dehydrase and lipid transport,10,2,4,3
PF16187,Peptidase_M16_M,Middle or third domain of peptidase_M16,10,1,0,0
PF00551,Formyl_trans_N,Formyl transferase,18,14,0,0
PF00043,GST_C,"Glutathione S-transferase, C-terminal domain",12,2,1,0
PF00245,Alk_phosphatase,Alkaline phosphatase,3,0,0,0
PF13532,2OG-FeII_Oxy_2,2OG-Fe(II) oxygenase superfamily,12,5,4,0
PF00059,Lectin_C,Lectin C-type domain,13,8,2,2
PF03281,Mab-21,Mab-21 protein,17,7,6,3
PF02041,Auxin_BP,Auxin binding protein,1,0,0,0
PF09268,Clathrin-link,"Clathrin, heavy-chain linker",2,1,0,0
PF15711,ILEI,Interleukin-like EMT inducer,6,1,0,0
PF01220,DHquinase_II,Dehydroquinase class II,31,0,2,0
PF00723,Glyco_hydro_15,Glycosyl hydrolases family 15,4,0,0,0
PF03447,NAD_binding_3,"Homoserine dehydrogenase, NAD binding domain",1,0,0,0
PF05053,Menin,Menin,21,3,2,0
PF07662,Nucleos_tra2_C,Na+ dependent nucleoside transporter C-terminus,9,0,1,0
PF00084,Sushi,Sushi repeat (SCR repeat),2,1,0,0
PF02233,PNTB,NAD(P) transhydrogenase beta subunit,3,3,2,1
PF01633,Choline_kinase,Choline/ethanolamine kinase,14,3,1,0
PF00567,TUDOR,Tudor domain,2,0,0,0
PF01467,CTP_transf_like,Cytidylyltransferase-like,13,6,3,0
PF03068,PAD,Protein-arginine deiminase (PAD),4,1,0,0
PF16355,DUF4982,Domain of unknown function (DUF4982),2,2,0,0
PF08934,Rb_C,Rb C-terminal domain,2,0,0,0
PF00631,G-gamma,GGL domain,15,0,1,0
PF08540,HMG_CoA_synt_C,Hydroxymethylglutaryl-coenzyme A synthase C terminal,1,0,0,0
PF00071,Ras,Ras family,15,2,3,0
PF17387,Glyco_hydro_59M,Glycosyl hydrolase family 59 central domain,7,0,0,0
PF00483,NTP_transferase,Nucleotidyl transferase,11,1,3,1
PF09294,Interfer-bind,"Interferon-alpha/beta receptor, fibronectin type III",15,1,0,0
PF02762,Cbl_N3,"CBL proto-oncogene N-terminus, SH2-like domain",2,1,1,0
PF00001,7tm_1,7 transmembrane receptor (rhodopsin family),17,4,3,1
PF00579,tRNA-synt_1b,tRNA synthetases class I (W and Y),13,5,4,4
PF09458,H_lectin,H-type lectin domain,2,1,0,0
PF02313,Fumarate_red_D,Fumarate reductase subunit D,4,2,2,0
PF06445,GyrI-like,GyrI-like small molecule binding domain,3,0,1,0
PF01915,Glyco_hydro_3_C,Glycosyl hydrolase family 3 C-terminal domain,4,0,0,0
PF00545,Ribonuclease,ribonuclease,6,3,0,0
PF00516,GP120,Envelope glycoprotein GP120,9,1,3,2
PF01503,PRA-PH,Phosphoribosyl-ATP pyrophosphohydrolase,2,0,1,1
PF03403,PAF-AH_p_II,"Platelet-activating factor acetylhydrolase, isoform II",19,3,5,1
PF00331,Glyco_hydro_10,Glycosyl hydrolase family 10,12,2,2,0
PF02784,Orn_Arg_deC_N,"Pyridoxal-dependent decarboxylase, pyridoxal binding domain",1,0,0,0
PF05456,eIF_4EBP,Eukaryotic translation initiation factor 4E binding protein (EIF4EBP),4,2,0,0
PF06479,Ribonuc_2-5A,Ribonuclease 2-5A,5,1,0,0
PF08541,ACP_syn_III_C,3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal,10,3,3,1
PF00836,Stathmin,Stathmin family,2,0,0,0
PF00062,Lys,C-type lysozyme/alpha-lactalbumin family,7,3,3,0
PF06438,HasA,Heme-binding protein A (HasA),2,1,0,0
PF07238,PilZ,PilZ domain,3,0,0,0
PF01431,Peptidase_M13,Peptidase family M13,8,0,0,0
PF12697,Abhydrolase_6,Alpha/beta hydrolase family,10,4,4,3
PF07859,Abhydrolase_3,alpha/beta hydrolase fold,2,1,1,0
PF02830,V4R,V4R domain,4,2,1,0
PF03426,CBM_15,Carbohydrate binding domain (family 15),1,1,0,0
PF00508,PPV_E2_N,"E2 (early) protein, N terminal",1,0,1,0
PF00617,RasGEF,RasGEF domain,9,3,1,0
PF01341,Glyco_hydro_6,Glycosyl hydrolases family 6,1,0,0,0
PF00202,Aminotran_3,Aminotransferase class-III,8,0,1,0
PF03024,Folate_rec,Folate receptor family,6,0,0,0
PF00328,His_Phos_2,Histidine phosphatase superfamily (branch 2),6,2,2,0
PF12934,FTO_CTD,FTO C-terminal domain,11,4,5,1
PF00781,DAGK_cat,Diacylglycerol kinase catalytic domain,4,1,1,0
PF02113,Peptidase_S13,D-Ala-D-Ala carboxypeptidase 3 (S13) family,9,3,3,1
PF00881,Nitroreductase,Nitroreductase family,3,0,0,0
PF00933,Glyco_hydro_3,Glycosyl hydrolase family 3 N terminal domain,5,3,1,0
PF00106,adh_short,short chain dehydrogenase,2,1,2,2
PF01808,AICARFT_IMPCHas,AICARFT/IMPCHase bienzyme,9,1,1,0
PF10220,Smg8_Smg9,Smg8_Smg9,1,0,0,0
PF00018,SH3_1,SH3 domain,18,5,2,1
PF12296,HsbA,Hydrophobic surface binding protein A,2,2,1,0
PF00294,PfkB,pfkB family carbohydrate kinase,23,11,4,1
PF00765,Autoind_synth,Autoinducer synthase,1,0,0,0
PF00005,ABC_tran,ABC transporter,8,3,0,0
PF08210,APOBEC_N,APOBEC-like N-terminal domain,1,0,0,0
PF08534,Redoxin,Redoxin,4,4,0,0
PF11969,DcpS_C,Scavenger mRNA decapping enzyme C-term binding,4,0,0,0
PF01421,Reprolysin,Reprolysin (M12B) family zinc metalloprotease,20,9,4,0
PF00188,CAP,Cysteine-rich secretory protein family,1,1,1,0
PF01055,Glyco_hydro_31,Glycosyl hydrolases family 31,14,1,2,0
PF08675,RNA_bind,RNA binding domain,3,1,0,0
PF08676,MutL_C,MutL C terminal dimerisation domain,2,0,0,0
PF00770,Peptidase_C5,Adenovirus endoprotease,6,0,1,0
PF00782,DSPc,"Dual specificity phosphatase, catalytic domain",1,1,0,0
PF02156,Glyco_hydro_26,Glycosyl hydrolase family 26,3,0,0,0
PF01400,Astacin,Astacin (Peptidase family M12A),1,0,0,0
PF09173,eIF2_C,"Initiation factor eIF2 gamma, C terminal",3,0,0,0
PF08778,HIF-1a_CTAD,HIF-1 alpha C terminal transactivation domain,1,0,0,0
PF00117,GATase,Glutamine amidotransferase class-I,1,0,0,0
PF00652,Ricin_B_lectin,Ricin-type beta-trefoil lectin domain,3,0,0,0
PF13202,EF-hand_5,EF hand,3,2,1,1
PF00543,P-II,Nitrogen regulatory protein P-II,12,2,1,0
PF02542,YgbB,YgbB family,7,1,3,2
PF03941,INCENP_ARK-bind,"Inner centromere protein, ARK binding region",7,3,0,0
PF00227,Proteasome,Proteasome subunit,2,0,0,0
PF00288,GHMP_kinases_N,GHMP kinases N terminal domain,9,4,0,0
PF08361,TetR_C_2,"MAATS-type transcriptional repressor, C-terminal region",3,2,2,1
PF18086,PPIP5K2_N,Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain,4,2,1,0
PF08264,Anticodon_1,Anticodon-binding domain of tRNA,7,3,1,0
PF03098,An_peroxidase,Animal haem peroxidase,5,0,0,0
PF05328,CybS,"CybS, succinate dehydrogenase cytochrome B small subunit",1,1,0,0
PF16963,PelD_GGDEF,PelD GGDEF domain,4,2,0,0
PF01487,DHquinase_I,Type I 3-dehydroquinase,3,0,0,0
PF01128,IspD,2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase,9,1,1,0
PF05726,Pirin_C,Pirin C-terminal cupin domain,1,0,0,0
PF14896,Arabino_trans_C,EmbC C-terminal domain,1,1,1,0
PF03147,FDX-ACB,Ferredoxin-fold anticodon binding domain,2,0,0,0
PF01817,CM_2,Chorismate mutase type II,1,0,0,0
PF03099,BPL_LplA_LipB,Biotin/lipoate A/B protein ligase family,1,0,0,0
PF02133,Transp_cyt_pur,"Permease for cytosine/purines, uracil, thiamine, allantoin",4,0,2,0
PF00972,Flavi_NS5,Flavivirus RNA-directed RNA polymerase,10,5,5,1
PF01023,S_100,S-100/ICaBP type calcium binding domain,2,2,1,1
PF00685,Sulfotransfer_1,Sulfotransferase domain,7,2,3,2
PF06431,Polyoma_lg_T_C,Polyomavirus large T antigen C-terminus,3,1,0,0
PF06330,TRI5,Trichodiene synthase (TRI5),4,2,0,0
PF01555,N6_N4_Mtase,DNA methylase,4,1,1,0
PF00883,Peptidase_M17,"Cytosol aminopeptidase family, catalytic domain",6,3,2,1
PF07804,HipA_C,HipA-like C-terminal domain,2,1,1,0
PF13500,AAA_26,AAA domain,4,2,0,0
PF00129,MHC_I,"Class I Histocompatibility antigen, domains alpha 1 and 2",2,0,0,0
PF00375,SDF,Sodium:dicarboxylate symporter family,4,2,1,1
PF03071,GNT-I,GNT-I family,1,0,0,0
PF00571,CBS,CBS domain,16,7,2,0
PF11032,ApoM,ApoM domain,1,0,0,0
PF07472,PA-IIL,Fucose-binding lectin II (PA-IIL),15,1,0,0
PF02513,Spin-Ssty,Spin/Ssty Family,4,2,1,0
PF04818,CTD_bind,RNA polymerase II-binding domain.,7,1,1,0
PF00632,HECT,HECT-domain (ubiquitin-transferase),1,1,0,0
PF00391,PEP-utilizers,"PEP-utilising enzyme, mobile domain",3,1,2,0
PF01243,Putative_PNPOx,Pyridoxamine 5'-phosphate oxidase,1,0,0,0
PF11413,HIF-1,Hypoxia-inducible factor-1,1,1,0,0
PF04960,Glutaminase,Glutaminase,13,6,6,3
PF01221,Dynein_light,Dynein light chain type 1,7,1,1,0
PF13407,Peripla_BP_4,Periplasmic binding protein domain,11,1,1,0
PF06153,CdAMP_rec,Cyclic-di-AMP receptor,3,0,0,0
PF01650,Peptidase_C13,Peptidase C13 family,1,0,0,0
PF01497,Peripla_BP_2,Periplasmic binding protein,14,4,1,0
PF00928,Adap_comp_sub,Adaptor complexes medium subunit family,7,1,1,0
PF02146,SIR2,Sir2 family,18,3,2,1
PF00790,VHS,VHS domain,11,0,0,0
PF01111,CKS,Cyclin-dependent kinase regulatory subunit,1,0,0,0
PF00187,Chitin_bind_1,Chitin recognition protein,3,2,1,1
PF01031,Dynamin_M,Dynamin central region,2,0,0,0
PF01513,NAD_kinase,ATP-NAD kinase,9,2,2,0
PF08435,Calici_coat_C,Calicivirus coat protein C-terminal,1,0,0,0
PF11896,DUF3416,Domain of unknown function (DUF3416),1,0,0,0
PF03331,LpxC,UDP-3-O-acyl N-acetylglycosamine deacetylase,18,1,1,0
PF02867,Ribonuc_red_lgC,"Ribonucleotide reductase, barrel domain",4,2,1,0
PF00240,ubiquitin,Ubiquitin family,5,0,0,0
PF01202,SKI,Shikimate kinase,5,1,2,0
PF00982,Glyco_transf_20,Glycosyltransferase family 20,1,1,0,0
PF00626,Gelsolin,Gelsolin repeat,1,1,0,0
PF09409,PUB,PUB domain,2,2,1,0
PF13336,AcetylCoA_hyd_C,Acetyl-CoA hydrolase/transferase C-terminal domain,2,1,1,0
PF00521,DNA_topoisoIV,"DNA gyrase/topoisomerase IV, subunit A",3,0,0,0
PF00535,Glycos_transf_2,Glycosyl transferase family 2,1,0,0,0
PF01734,Patatin,Patatin-like phospholipase,1,0,0,0
PF00368,HMG-CoA_red,Hydroxymethylglutaryl-coenzyme A reductase,13,0,1,0
PF01177,Asp_Glu_race,Asp/Glu/Hydantoin racemase,5,1,3,1
PF12974,Phosphonate-bd,"ABC transporter, phosphonate, periplasmic substrate-binding protein",1,0,0,0
PF11838,ERAP1_C,ERAP1-like C-terminal domain,8,1,1,0
PF16591,HBM,Helical bimodular sensor domain,1,0,1,0
PF04198,Sugar-bind,Putative sugar-binding domain,8,2,2,1
PF14593,PH_3,PH domain,2,0,1,0
PF02799,NMT_C,"Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain",14,3,3,0
PF00169,PH,PH domain,6,1,3,0
PF00501,AMP-binding,AMP-binding enzyme,3,1,1,0
PF03727,Hexokinase_2,Hexokinase,4,0,0,0
PF07828,PA-IL,PA-IL-like protein,18,7,2,1
PF00054,Laminin_G_1,Laminin G domain,5,0,1,0
PF02932,Neur_chan_memb,Neurotransmitter-gated ion-channel transmembrane region,1,0,0,0
PF00354,Pentaxin,Pentaxin family,8,3,2,0
PF13417,GST_N_3,"Glutathione S-transferase, N-terminal domain",3,2,1,0
PF00425,Chorismate_bind,chorismate binding enzyme,7,4,2,0
PF05175,MTS,Methyltransferase small domain,2,0,1,0
PF12470,SUFU_C,Suppressor of Fused Gli/Ci N terminal binding domain,2,0,1,0
PF01373,Glyco_hydro_14,Glycosyl hydrolase family 14,3,3,0,0
PF06003,SMN,Survival motor neuron protein (SMN),4,0,0,0
PF02836,Glyco_hydro_2_C,"Glycosyl hydrolases family 2, TIM barrel domain",4,1,1,0
PF01483,P_proprotein,Proprotein convertase P-domain,3,2,0,0
PF07980,SusD_RagB,SusD family,3,1,0,0
PF05743,UEV,UEV domain,5,2,0,0
PF07081,DUF1349,Protein of unknown function (DUF1349),1,1,1,0
PF03372,Exo_endo_phos,Endonuclease/Exonuclease/phosphatase family,5,1,2,0
PF17189,Glyco_hydro_30C,Glycosyl hydrolase family 30 beta sandwich domain,7,0,0,0
PF13424,TPR_12,Tetratricopeptide repeat,4,0,1,0
PF08502,LeuA_dimer,LeuA allosteric (dimerisation) domain,2,1,1,0
PF02806,Alpha-amylase_C,"Alpha amylase, C-terminal all-beta domain",10,2,0,0
PF03167,UDG,Uracil DNA glycosylase superfamily,6,1,2,0
PF00718,Polyoma_coat,Polyomavirus coat protein,3,1,0,0
PF03931,Skp1_POZ,"Skp1 family, tetramerisation domain",2,0,0,0
PF02748,PyrI_C,"Aspartate carbamoyltransferase regulatory chain, metal binding domain",8,1,3,0
PF00351,Biopterin_H,Biopterin-dependent aromatic amino acid hydroxylase,11,3,3,0
PF03828,PAP_assoc,Cid1 family poly A polymerase,2,2,2,0
PF03261,CDK5_activator,Cyclin-dependent kinase 5 activator protein,4,2,0,0
PF00087,Toxin_TOLIP,Snake toxin and toxin-like protein,1,0,0,0
PF03201,HMD,"H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase",2,0,0,0
PF04386,SspB,Stringent starvation protein B,1,0,0,0
PF03949,Malic_M,"Malic enzyme, NAD binding domain",2,0,0,0
PF00696,AA_kinase,Amino acid kinase family,1,1,0,0
PF03556,Cullin_binding,Cullin binding,5,1,1,1
PF02820,MBT,mbt repeat,7,1,0,0
PF00679,EFG_C,Elongation factor G C-terminus,3,0,0,0
PF01361,Tautomerase,Tautomerase enzyme,2,1,0,0
PF03637,Mob1_phocein,Mob1/phocein family,3,0,0,0
PF00082,Peptidase_S8,Subtilase family,1,0,0,0
PF07744,SPOC,SPOC domain,1,0,0,0
PF03991,Prion_octapep,Copper binding octapeptide repeat,1,0,0,0
PF03466,LysR_substrate,LysR substrate binding domain,6,2,4,2
PF02406,MmoB_DmpM,MmoB/DmpM family,1,0,0,0
PF09223,ZinT,ZinT (YodA) periplasmic lipocalin-like zinc-recruitment,1,0,0,0
PF10565,NMDAR2_C,N-methyl D-aspartate receptor 2B3 C-terminus,1,1,0,0
PF00703,Glyco_hydro_2,Glycosyl hydrolases family 2,8,1,0,0
PF14602,Hexapep_2,Hexapeptide repeat of succinyl-transferase,2,1,0,0
PF09221,Bacteriocin_IId,Bacteriocin class IId cyclical uberolysin-like,1,0,0,0
PF00149,Metallophos,Calcineurin-like phosphoesterase,11,0,2,0
PF05028,PARG_cat,Poly (ADP-ribose) glycohydrolase (PARG),1,0,0,0
PF00162,PGK,Phosphoglycerate kinase,6,1,1,1
PF02267,Rib_hydrolayse,ADP-ribosyl cyclase,7,1,0,0
PF08715,Viral_protease,Papain like viral protease,3,0,0,0
PF03630,Fumble,Fumble,5,1,0,0
PF07311,Dodecin,Dodecin,5,4,2,0
PF12891,Glyco_hydro_44,Glycoside hydrolase family 44,2,1,0,0
PF00917,MATH,MATH domain,3,2,0,0
PF00684,DnaJ_CXXCXGXG,DnaJ central domain,1,0,0,0
PF17982,C5HCH,NSD Cys-His rich domain,1,0,0,0
PF13463,HTH_27,Winged helix DNA-binding domain,2,0,1,0
PF00648,Peptidase_C2,Calpain family cysteine protease,4,0,0,0
PF08029,HisG_C,"HisG, C-terminal domain",1,0,0,0
PF01408,GFO_IDH_MocA,"Oxidoreductase family, NAD-binding Rossmann fold",2,0,0,0
PF17390,Bac_rhamnosid_C,Bacterial alpha-L-rhamnosidase C-terminal domain,1,0,0,0
PF05147,LANC_like,Lanthionine synthetase C-like protein,1,0,0,0
PF08544,GHMP_kinases_C,GHMP kinases C terminal,1,0,1,0
PF14791,DNA_pol_B_thumb,DNA polymerase beta thumb,3,0,0,0
PF03061,4HBT,Thioesterase superfamily,1,0,0,0
PF13833,EF-hand_8,EF-hand domain pair,3,0,0,0
PF07653,SH3_2,Variant SH3 domain,2,1,0,0
PF11713,Peptidase_C80,Peptidase C80 family,3,0,2,2
PF00787,PX,PX domain,1,0,0,0
PF00548,Peptidase_C3,3C cysteine protease (picornain 3C),8,4,3,0
PF00689,Cation_ATPase_C,"Cation transporting ATPase, C-terminus",4,0,1,0
PF02421,FeoB_N,Ferrous iron transport protein B,7,6,0,0
PF00731,AIRC,AIR carboxylase,5,0,2,0
PF13343,SBP_bac_6,Bacterial extracellular solute-binding protein,4,0,1,0
PF00006,ATP-synt_ab,"ATP synthase alpha/beta family, nucleotide-binding domain",2,0,0,0
PF01652,IF4E,Eukaryotic initiation factor 4E,6,1,0,0
PF00158,Sigma54_activat,Sigma-54 interaction domain,1,0,0,0
PF00541,Adeno_knob,Adenoviral fibre protein (knob domain),3,0,0,0
PF07969,Amidohydro_3,Amidohydrolase family,1,0,0,0
PF02898,NO_synthase,"Nitric oxide synthase, oxygenase domain",2,0,0,0
PF00092,VWA,von Willebrand factor type A domain,11,2,2,0
PF08718,GLTP,Glycolipid transfer protein (GLTP),3,1,1,0
PF09066,B2-adapt-app_C,"Beta2-adaptin appendage, C-terminal sub-domain",1,1,0,0
PF02172,KIX,KIX domain,1,0,0,0
PF08761,dUTPase_2,dUTPase,4,1,1,0
PF16719,SAWADEE,SAWADEE domain,4,0,0,0
PF02664,LuxS,S-Ribosylhomocysteinase (LuxS),2,1,0,0
PF00478,IMPDH,IMP dehydrogenase / GMP reductase domain,6,2,0,0
PF01473,CW_binding_1,Putative cell wall binding repeat,1,1,1,0
PF00475,IGPD,Imidazoleglycerol-phosphate dehydratase,2,0,0,0
PF00565,SNase,Staphylococcal nuclease homologue,2,0,0,0
PF02617,ClpS,ATP-dependent Clp protease adaptor protein ClpS,2,0,0,0
PF13857,Ank_5,Ankyrin repeats (many copies),2,1,1,0
PF13927,Ig_3,Immunoglobulin domain,2,1,1,1
PF13374,TPR_10,Tetratricopeptide repeat,1,1,0,0
PF10400,Vir_act_alpha_C,Virulence activator alpha C-term,1,0,0,0
PF12605,CK1gamma_C,Casein kinase 1 gamma C terminal,4,2,0,0
PF00364,Biotin_lipoyl,Biotin-requiring enzyme,3,2,1,1
PF04267,SoxD,"Sarcosine oxidase, delta subunit family",2,0,0,0
PF02800,Gp_dh_C,"Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain",4,3,0,0
PF01536,SAM_decarbox,Adenosylmethionine decarboxylase,9,6,5,1
PF14604,SH3_9,Variant SH3 domain,3,0,0,0
PF05721,PhyH,Phytanoyl-CoA dioxygenase (PhyH),1,1,0,0
PF04548,AIG1,AIG1 family,4,1,0,0
PF01640,Peptidase_C10,Peptidase C10 family,4,1,0,0
PF09401,NSP10,RNA synthesis protein NSP10,2,1,0,0
PF02196,RBD,Raf-like Ras-binding domain,1,0,0,0
PF11941,DUF3459,Domain of unknown function (DUF3459),2,0,1,0
PF00759,Glyco_hydro_9,Glycosyl hydrolase family 9,3,2,0,0
PF00167,FGF,Fibroblast growth factor,7,5,2,0
PF08546,ApbA_C,Ketopantoate reductase PanE/ApbA C terminal,1,0,1,0
PF12146,Hydrolase_4,"Serine aminopeptidase, S33",2,2,2,1
PF00882,Zn_dep_PLPC,Zinc dependent phospholipase C,2,1,0,0
PF00715,IL2,Interleukin 2,3,0,0,0
PF07615,Ykof,YKOF-related Family,1,0,0,0
PF08666,SAF,SAF domain,3,1,1,1
PF15688,NRIP1_repr_2,Nuclear receptor-interacting protein 1 repression 2,2,0,0,0
PF02502,LacAB_rpiB,Ribose/Galactose Isomerase,4,2,0,0
PF00949,Peptidase_S7,"Peptidase S7, Flavivirus NS3 serine protease",3,1,1,1
PF02401,LYTB,LytB protein,2,1,1,0
PF00270,DEAD,DEAD/DEAH box helicase,1,1,1,1
PF16849,Glyco_transf_88,Glycosyltransferase family 88,1,0,0,0
PF00235,Profilin,Profilin,1,1,1,0
PF01363,FYVE,FYVE zinc finger,1,1,0,0
PF10415,FumaraseC_C,Fumarase C C-terminus,1,0,0,0
PF00709,Adenylsucc_synt,Adenylosuccinate synthetase,4,0,2,0
PF01663,Phosphodiest,Type I phosphodiesterase / nucleotide pyrophosphatase,3,1,1,0
PF07831,PYNP_C,Pyrimidine nucleoside phosphorylase C-terminal domain,3,1,0,0
PF17137,DUF5110,Domain of unknown function (DUF5110),7,0,0,0
PF01063,Aminotran_4,Amino-transferase class IV,1,1,0,0
PF00378,ECH_1,Enoyl-CoA hydratase/isomerase,3,0,0,0
PF03105,SPX,SPX domain,2,1,0,0
PF01731,Arylesterase,Arylesterase,1,0,0,0
PF02171,Piwi,Piwi domain,6,5,1,0
PF00583,Acetyltransf_1,Acetyltransferase (GNAT) family,5,1,0,0
PF02254,TrkA_N,TrkA-N domain,3,0,0,0
PF00041,fn3,Fibronectin type III domain,3,0,0,0
PF03401,TctC,Tripartite tricarboxylate transporter family receptor,1,1,0,0
PF03264,Cytochrom_NNT,"NapC/NirT cytochrome c family, N-terminal region",1,1,1,0
PF13489,Methyltransf_23,Methyltransferase domain,6,4,3,2
PF02738,Ald_Xan_dh_C2,Molybdopterin-binding domain of aldehyde dehydrogenase,1,0,0,0
PF03663,Glyco_hydro_76,Glycosyl hydrolase family 76,3,2,1,0
PF00025,Arf,ADP-ribosylation factor family,1,0,0,0
PF08674,AChE_tetra,Acetylcholinesterase tetramerisation domain,1,0,0,0
PF08324,PUL,PUL domain,1,0,0,0
PF00398,RrnaAD,Ribosomal RNA adenine dimethylase,2,0,0,0
PF09291,DUF1968,Domain of unknown function (DUF1968),1,0,0,0
PF13844,Glyco_transf_41,Glycosyl transferase family 41,7,0,1,0
PF01237,Oxysterol_BP,Oxysterol-binding protein,1,0,0,0
PF18116,SNX17_FERM_C,Sorting Nexin 17 FERM C-terminal domain,1,0,0,0
PF13692,Glyco_trans_1_4,Glycosyl transferases group 1,2,0,0,0
PF01437,PSI,Plexin repeat,1,0,0,0
PF03481,SUA5,Putative GTP-binding controlling metal-binding,1,0,0,0
PF07478,Dala_Dala_lig_C,D-ala D-ala ligase C-terminus,1,0,0,0
PF00098,zf-CCHC,Zinc knuckle,1,1,0,0
PF00264,Tyrosinase,Common central domain of tyrosinase,2,2,1,0
PF00550,PP-binding,Phosphopantetheine attachment site,2,0,0,0
PF03253,UT,Urea transporter,1,1,0,0
PF17209,Hfq,Hfq protein,2,0,0,0
PF00248,Aldo_ket_red,Aldo/keto reductase family,2,1,0,0
PF01195,Pept_tRNA_hydro,Peptidyl-tRNA hydrolase,2,1,1,1
PF00990,GGDEF,"Diguanylate cyclase, GGDEF domain",3,0,0,0
PF02126,PTE,Phosphotriesterase family,3,1,1,1
PF02629,CoA_binding,CoA binding domain,2,1,0,0
PF00091,Tubulin,"Tubulin/FtsZ family, GTPase domain",1,0,0,0
PF16658,RF3_C,"Class II release factor RF3, C-terminal domain",1,0,0,0
PF12763,EF-hand_4,Cytoskeletal-regulatory complex EF hand,1,0,1,0
PF12972,NAGLU_C,Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain,2,0,0,0
PF10469,AKAP7_NLS,AKAP7 2'5' RNA ligase-like domain,1,1,0,0
PF06941,NT5C,"5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)",3,2,1,0
PF04551,GcpE,GcpE protein,2,0,2,0
PF00426,VP4_haemagglut,Outer Capsid protein VP4 (Hemagglutinin) Concanavalin-like domain,2,1,1,0
PF00960,Neocarzinostat,Neocarzinostatin family,2,0,0,0
PF00408,PGM_PMM_IV,"Phosphoglucomutase/phosphomannomutase, C-terminal domain",2,1,1,1
PF01244,Peptidase_M19,Membrane dipeptidase (Peptidase family M19),2,0,1,0
PF00867,XPG_I,XPG I-region,1,1,0,0
PF02036,SCP2,SCP-2 sterol transfer family,1,1,0,0
PF00243,NGF,Nerve growth factor family,1,0,0,0
PF00520,Ion_trans,Ion transport protein,4,0,0,0
PF00563,EAL,EAL domain,5,0,0,0
PF03496,ADPrib_exo_Tox,ADP-ribosyltransferase exoenzyme,3,1,0,0
PF00305,Lipoxygenase,Lipoxygenase,1,0,0,0
PF00072,Response_reg,Response regulator receiver domain,1,0,0,0
PF17725,YBD,YAP binding domain,2,2,1,0
PF01042,Ribonuc_L-PSP,Endoribonuclease L-PSP,1,0,0,0
PF03145,Sina,Seven in absentia protein family,1,1,0,0
PF01786,AOX,Alternative oxidase,2,0,1,0
PF00633,HHH,Helix-hairpin-helix motif,2,0,0,0
PF04952,AstE_AspA,Succinylglutamate desuccinylase / Aspartoacylase family,1,0,0,0
PF00481,PP2C,Protein phosphatase 2C,2,0,2,1
PF10609,ParA,NUBPL iron-transfer P-loop NTPase,1,1,0,0
PF17981,ADD_ATRX,Cysteine Rich ADD domain,1,0,0,0
PF08244,Glyco_hydro_32C,Glycosyl hydrolases family 32 C terminal,1,1,0,0
PF00779,BTK,BTK motif,2,0,2,2
PF06433,Me-amine-dh_H,Methylamine dehydrogenase heavy chain (MADH),3,0,0,0
PF01453,B_lectin,D-mannose binding lectin,1,1,0,0
PF05222,AlaDh_PNT_N,"Alanine dehydrogenase/PNT, N-terminal domain",2,1,0,0
PF10017,Methyltransf_33,"Histidine-specific methyltransferase, SAM-dependent",2,1,0,0
PF11717,Tudor-knot,RNA binding activity-knot of a chromodomain,2,1,0,0
PF00682,HMGL-like,HMGL-like,2,2,2,1
PF01019,G_glu_transpept,Gamma-glutamyltranspeptidase,2,0,0,0
PF01593,Amino_oxidase,Flavin containing amine oxidoreductase,3,0,0,0
PF04799,Fzo_mitofusin,fzo-like conserved region,2,1,1,0
PF08282,Hydrolase_3,haloacid dehalogenase-like hydrolase,1,0,0,0
PF03662,Glyco_hydro_79n,"Glycosyl hydrolase family 79, N-terminal domain",1,0,0,0
PF12104,Tcell_CD4_C,T cell CD4 receptor C terminal region,1,0,0,0
PF02747,PCNA_C,"Proliferating cell nuclear antigen, C-terminal domain",2,1,0,0
PF01261,AP_endonuc_2,Xylose isomerase-like TIM barrel,1,1,1,1
PF00581,Rhodanese,Rhodanese-like domain,2,1,1,0
PF00218,IGPS,Indole-3-glycerol phosphate synthase,4,2,1,0
PF04203,Sortase,Sortase family,1,0,0,0
PF09021,HutP,HutP,1,1,1,0
PF00022,Actin,Actin,4,1,1,1
PF13177,DNA_pol3_delta2,"DNA polymerase III, delta subunit",1,0,0,0
PF06436,Pneumovirus_M2,Pneumovirus matrix protein 2 (M2),1,0,0,0
PF03074,GCS,Glutamate-cysteine ligase,1,0,0,0
PF09515,Thia_YuaJ,Thiamine transporter protein (Thia_YuaJ),3,0,0,0
PF01358,PARP_regulatory,Poly A polymerase regulatory subunit,4,2,2,1
PF00702,Hydrolase,haloacid dehalogenase-like hydrolase,4,1,2,0
PF00014,Kunitz_BPTI,Kunitz/Bovine pancreatic trypsin inhibitor domain,1,0,0,0
PF03366,YEATS,YEATS family,1,0,0,0
PF02574,S-methyl_trans,Homocysteine S-methyltransferase,1,0,0,0
PF00023,Ank,Ankyrin repeat,2,0,0,0
PF09115,DNApol3-delta_C,"DNA polymerase III, delta subunit, C terminal",2,0,0,0
PF04008,Adenosine_kin,Adenosine specific kinase,1,0,0,0
PF16457,PH_12,Pleckstrin homology domain,1,0,0,0
PF09007,EBP50_C,"EBP50, C-terminal",1,1,0,0
PF06026,Rib_5-P_isom_A,Ribose 5-phosphate isomerase A (phosphoriboisomerase A),2,0,0,0
PF00085,Thioredoxin,Thioredoxin,1,0,0,0
PF00401,ATP-synt_DE,"ATP synthase, Delta/Epsilon chain, long alpha-helix domain",1,1,0,0
PF16874,Glyco_hydro_36C,Glycosyl hydrolase family 36 C-terminal domain,1,1,0,0
PF16518,GrlR,"T3SS negative regulator,GrlR",1,1,0,0
PF09222,Fim-adh_lectin,"Fimbrial adhesin F17-AG, lectin domain",1,0,0,0
PF08448,PAS_4,PAS fold,1,1,1,0
PF04901,RAMP,Receptor activity modifying family,2,0,0,0
PF00049,Insulin,Insulin/IGF/Relaxin family,1,0,0,0
PF14200,RicinB_lectin_2,Ricin-type beta-trefoil lectin domain-like,2,0,1,0
PF01557,FAA_hydrolase,Fumarylacetoacetate (FAA) hydrolase family,2,0,1,1
PF00147,Fibrinogen_C,"Fibrinogen beta and gamma chains, C-terminal globular domain",2,1,0,0
PF03133,TTL,Tubulin-tyrosine ligase family,5,0,0,0
PF02157,Man-6-P_recep,Mannose-6-phosphate receptor,2,0,0,0
PF00325,Crp,"Bacterial regulatory proteins, crp family",1,1,1,0
PF13507,GATase_5,CobB/CobQ-like glutamine amidotransferase domain,1,0,0,0
PF02887,PK_C,"Pyruvate kinase, alpha/beta domain",4,3,1,0
PF00152,tRNA-synt_2,"tRNA synthetases class II (D, K and N)",3,0,0,0
PF02803,Thiolase_C,"Thiolase, C-terminal domain",3,1,1,0
PF02883,Alpha_adaptinC2,Adaptin C-terminal domain,2,1,1,0
PF14714,KH_dom-like,"KH-domain-like of EngA bacterial GTPase enzymes, C-terminal",2,1,0,0
PF02390,Methyltransf_4,Putative methyltransferase,3,0,1,0
PF03734,YkuD,"L,D-transpeptidase catalytic domain",1,0,0,0
PF05733,Tenui_N,Tenuivirus/Phlebovirus nucleocapsid protein,1,1,0,0
PF01614,IclR,Bacterial transcriptional regulator,1,0,0,0
PF02222,ATP-grasp,ATP-grasp domain,1,1,0,0
PF01470,Peptidase_C15,Pyroglutamyl peptidase,1,0,1,0
PF02753,PapD_C,"Pili assembly chaperone PapD, C-terminal domain",1,0,0,0
PF02492,cobW,"CobW/HypB/UreG, nucleotide-binding domain",2,1,1,0
PF00560,LRR_1,Leucine Rich Repeat,1,0,0,0
PF03422,CBM_6,Carbohydrate binding module (family 6),2,0,0,0
PF13720,Acetyltransf_11,Udp N-acetylglucosamine O-acyltransferase; Domain 2,1,0,0,0
PF11104,PilM_2,Type IV pilus assembly protein PilM;,1,0,0,0
PF09239,Topo-VIb_trans,"Topoisomerase VI B subunit, transducer",1,0,0,0
PF00724,Oxidored_FMN,NADH:flavin oxidoreductase / NADH oxidase family,1,1,1,1
PF04209,HgmA,"homogentisate 1,2-dioxygenase",1,0,1,0
PF07943,PBP5_C,"Penicillin-binding protein 5, C-terminal domain",2,1,1,0
PF17913,FHA_2,FHA domain,1,0,0,0
PF08543,Phos_pyr_kin,Phosphomethylpyrimidine kinase,2,1,0,0
PF05199,GMC_oxred_C,GMC oxidoreductase,1,0,0,0
PF00498,FHA,FHA domain,4,1,1,0
PF02565,RecO_C,Recombination protein O C terminal,1,0,0,0
PF01842,ACT,ACT domain,2,1,0,0
PF16411,SusF_SusE,Outer membrane protein SusF_SusE,2,0,0,0
PF00534,Glycos_transf_1,Glycosyl transferases group 1,5,2,1,0
PF01344,Kelch_1,Kelch motif,6,0,1,0
PF01704,UDPGP,UTP--glucose-1-phosphate uridylyltransferase,1,0,0,0
PF02884,Lyase_8_C,"Polysaccharide lyase family 8, C-terminal beta-sandwich domain",2,0,0,0
PF06001,DUF902,Domain of Unknown Function (DUF902),3,0,0,0
PF01239,PPTA,Protein prenyltransferase alpha subunit repeat,1,0,0,0
PF02311,AraC_binding,AraC-like ligand binding domain,1,0,0,0
PF18104,Tudor_2,Jumonji domain-containing protein 2A Tudor domain,1,0,0,0
PF10425,SdrG_C_C,C-terminus of bacterial fibrinogen-binding adhesin,2,0,0,0
PF02973,Sialidase,"Sialidase, N-terminal domain",1,0,0,0
PF00229,TNF,TNF(Tumour Necrosis Factor) family,2,1,1,0
PF02087,Nitrophorin,Nitrophorin,1,0,0,0
PF17645,Amdase,Arylmalonate decarboxylase,1,0,0,0
PF11852,DUF3372,Domain of unknown function (DUF3372),1,0,0,0
PF13859,BNR_3,BNR repeat-like domain,1,0,0,0
PF01575,MaoC_dehydratas,MaoC like domain,3,2,0,0
PF08447,PAS_3,PAS fold,1,0,0,0
PF05173,DapB_C,"Dihydrodipicolinate reductase, C-terminus",1,1,0,0
PF04146,YTH,YT521-B-like domain,1,0,0,0
PF00693,Herpes_TK,Thymidine kinase from herpesvirus,2,0,0,0
PF00480,ROK,ROK family,2,0,0,0
PF01432,Peptidase_M3,Peptidase family M3,1,0,0,0
PF03392,OS-D,"Insect pheromone-binding family, A10/OS-D",2,0,0,0
PF01163,RIO1,RIO1 family,2,1,1,1
PF00457,Glyco_hydro_11,Glycosyl hydrolases family 11,1,0,0,0
PF10431,ClpB_D2-small,"C-terminal, D2-small domain, of ClpB protein",2,1,0,0
PF00282,Pyridoxal_deC,Pyridoxal-dependent decarboxylase conserved domain,1,0,0,0
PF02081,TrpBP,Tryptophan RNA-binding attenuator protein,1,1,0,0
PF02733,Dak1,Dak1 domain,1,0,0,0
PF05157,T2SSE_N,"Type II secretion system (T2SS), protein E, N-terminal domain",1,0,0,0
PF12804,NTP_transf_3,MobA-like NTP transferase domain,1,0,0,0
PF03740,PdxJ,Pyridoxal phosphate biosynthesis protein PdxJ,1,1,1,1
PF00419,Fimbrial,Fimbrial protein,1,0,0,0
PF16420,ATG7_N,Ubiquitin-like modifier-activating enzyme ATG7 N-terminus,1,0,0,0
PF13432,TPR_16,Tetratricopeptide repeat,1,0,0,0
PF13242,Hydrolase_like,HAD-hyrolase-like,1,0,0,0
PF07516,SecA_SW,SecA Wing and Scaffold domain,1,1,0,0
PF02197,RIIa,Regulatory subunit of type II PKA R-subunit,1,1,1,0
PF14008,Metallophos_C,Iron/zinc purple acid phosphatase-like protein C,3,0,0,0
PF02230,Abhydrolase_2,Phospholipase/Carboxylesterase,2,0,0,0
PF00406,ADK,Adenylate kinase,1,0,1,0
PF05049,IIGP,Interferon-inducible GTPase (IIGP),2,0,0,0
PF07821,Alpha-amyl_C2,Alpha-amylase C-terminal beta-sheet domain,1,0,0,0
PF08881,CVNH,CVNH domain,1,1,1,0
PF00020,TNFR_c6,TNFR/NGFR cysteine-rich region,1,0,0,0
PF00285,Citrate_synt,"Citrate synthase, C-terminal domain",1,1,1,0
PF13620,CarboxypepD_reg,Carboxypeptidase regulatory-like domain,2,0,1,0
PF00992,Troponin,Troponin,2,2,1,1
PF01474,DAHP_synth_2,Class-II DAHP synthetase family,1,0,0,0
PF15519,RBM39linker,linker between RRM2 and RRM3 domains in RBM39 protein,1,0,0,0
PF02136,NTF2,Nuclear transport factor 2 (NTF2) domain,2,1,2,0
PF09425,CCT_2,Divergent CCT motif,1,0,0,0
PF02816,Alpha_kinase,Alpha-kinase family,2,2,0,0
PF13350,Y_phosphatase3,Tyrosine phosphatase family,1,0,0,0
PF05419,GUN4,GUN4-like,2,0,1,0
PF01124,MAPEG,MAPEG family,1,0,0,0
PF03309,Pan_kinase,Type III pantothenate kinase,2,1,0,0
PF00009,GTP_EFTU,Elongation factor Tu GTP binding domain,3,1,0,0
PF00878,CIMR,Cation-independent mannose-6-phosphate receptor repeat,2,1,0,0
PF08336,P4Ha_N,"Prolyl 4-Hydroxylase alpha-subunit, N-terminal region",2,0,0,0
PF10459,Peptidase_S46,Peptidase S46,1,0,0,0
PF14396,CFTR_R,"Cystic fibrosis TM conductance regulator (CFTR), regulator domain",1,0,0,0
PF13419,HAD_2,Haloacid dehalogenase-like hydrolase,4,1,1,0
PF00622,SPRY,SPRY domain,3,1,1,0
PF00393,6PGD,"6-phosphogluconate dehydrogenase, C-terminal domain",2,2,1,0
PF13180,PDZ_2,PDZ domain,2,0,0,0
PF14559,TPR_19,Tetratricopeptide repeat,2,1,0,0
PF02567,PhzC-PhzF,Phenazine biosynthesis-like protein,1,0,0,0
PF07212,Hyaluronidase_1,Hyaluronidase protein (HylP),1,0,0,0
PF01417,ENTH,ENTH domain,1,1,1,1
PF04909,Amidohydro_2,Amidohydrolase,1,1,1,1
PF02773,S-AdoMet_synt_C,"S-adenosylmethionine synthetase, C-terminal domain",1,0,0,0
PF01583,APS_kinase,Adenylylsulphate kinase,1,0,0,0
PF07968,Leukocidin,Leukocidin/Hemolysin toxin family,1,1,0,0
PF12796,Ank_2,Ankyrin repeats (3 copies),2,0,0,0
PF00568,WH1,WH1 domain,2,0,0,0
PF01857,RB_B,Retinoblastoma-associated protein B domain,1,0,0,0
PF03193,RsgA_GTPase,RsgA GTPase,1,0,0,0
PF10409,PTEN_C2,C2 domain of PTEN tumour-suppressor protein,1,0,1,1
PF01887,SAM_adeno_trans,S-adenosyl-l-methionine hydroxide adenosyltransferase,1,0,0,0
PF01501,Glyco_transf_8,Glycosyl transferase family 8,2,0,0,0
PF00302,CAT,Chloramphenicol acetyltransferase,1,1,0,0
PF00891,Methyltransf_2,O-methyltransferase,1,0,0,0
PF01302,CAP_GLY,CAP-Gly domain,1,0,0,0
PF12826,HHH_2,Helix-hairpin-helix motif,1,0,0,0
PF00456,Transketolase_N,"Transketolase, thiamine diphosphate binding domain",4,2,0,0
PF12919,TcdA_TcdB,TcdA/TcdB catalytic glycosyltransferase domain,2,1,0,0
PF16918,PknG_TPR,Protein kinase G tetratricopeptide repeat,1,0,0,0
PF13531,SBP_bac_11,Bacterial extracellular solute-binding protein,2,1,2,0
PF00221,Lyase_aromatic,Aromatic amino acid lyase,1,0,0,0
PF13522,GATase_6,Glutamine amidotransferase domain,1,0,0,0
PF07736,CM_1,Chorismate mutase type I,1,0,0,0
PF00278,Orn_DAP_Arg_deC,"Pyridoxal-dependent decarboxylase, C-terminal sheet domain",2,1,0,0
PF00301,Rubredoxin,Rubredoxin,2,1,0,0
PF00484,Pro_CA,Carbonic anhydrase,1,0,0,0
PF09359,VTC,VTC domain,1,1,0,0
PF05239,PRC,PRC-barrel domain,3,2,1,0
PF03936,Terpene_synth_C,"Terpene synthase family, metal binding domain",3,1,0,0
PF00267,Porin_1,Gram-negative porin,1,0,0,0
PF16497,MHC_I_3,MHC-I family domain,1,0,0,0
PF00977,His_biosynth,Histidine biosynthesis protein,1,1,1,0
PF00927,Transglut_C,"Transglutaminase family, C-terminal ig like domain",1,1,0,0
PF16589,BRCT_2,"BRCT domain, a BRCA1 C-terminus domain",4,2,1,0
PF03095,PTPA,Phosphotyrosyl phosphate activator (PTPA) protein,1,1,0,0
PF04616,Glyco_hydro_43,Glycosyl hydrolases family 43,1,1,1,0
PF00210,Ferritin,Ferritin-like domain,1,0,0,0
PF08450,SGL,SMP-30/Gluconolaconase/LRE-like region,1,0,0,0
PF02833,DHHA2,DHHA2 domain,1,0,0,0
PF04072,LCM,Leucine carboxyl methyltransferase,1,1,0,0
PF00566,RabGAP-TBC,Rab-GTPase-TBC domain,1,0,0,0
PF00691,OmpA,OmpA family,1,0,0,0
PF03415,Peptidase_C11,Clostripain family,1,1,0,0
PF00755,Carn_acyltransf,Choline/Carnitine o-acyltransferase,2,1,1,0
PF13181,TPR_8,Tetratricopeptide repeat,1,0,0,0
PF16657,Malt_amylase_C,"Maltogenic Amylase, C-terminal domain",1,0,0,0
PF02296,Alpha_adaptin_C,"Alpha adaptin AP2, C-terminal domain",1,0,0,0
PF03031,NIF,NLI interacting factor-like phosphatase,1,0,0,0
PF08569,Mo25,Mo25-like,1,1,0,0
PF02174,IRS,PTB domain (IRS-1 type),1,0,0,0
PF04868,PDE6_gamma,"Retinal cGMP phosphodiesterase, gamma subunit",1,1,1,1
PF03943,TAP_C,TAP C-terminal domain,2,0,0,0
PF00906,Hepatitis_core,Hepatitis core antigen,1,0,1,1
PF05336,rhaM,L-rhamnose mutarotase,1,0,0,0
PF16990,CBM_35,Carbohydrate binding module (family 35),1,0,0,0
PF00575,S1,S1 RNA binding domain,1,0,0,0
PF01380,SIS,SIS domain,1,0,1,1
PF09038,53-BP1_Tudor,Tumour suppressor p53-binding protein-1 Tudor,2,0,0,0
PF16629,Arm_APC_u3,Armadillo-associated region on APC,1,0,0,0
PF00124,Photo_RC,Photosynthetic reaction centre protein,1,0,0,0
PF02665,Nitrate_red_gam,Nitrate reductase gamma subunit,1,1,1,0
PF03126,Plus-3,Plus-3 domain,1,0,0,0
PF01869,BcrAD_BadFG,BadF/BadG/BcrA/BcrD ATPase family,1,0,0,0
PF16780,AIMP2_LysRS_bd,AIMP2 lysyl-tRNA synthetase binding domain,2,0,1,0
PF00307,CH,Calponin homology (CH) domain,1,0,0,0
PF03088,Str_synth,Strictosidine synthase,1,0,0,0
PF00388,PI-PLC-X,"Phosphatidylinositol-specific phospholipase C, X domain",1,1,0,0
PF02264,LamB,LamB porin,1,0,0,0
PF14026,DUF4242,Protein of unknown function (DUF4242),1,0,0,0
PF13520,AA_permease_2,Amino acid permease,1,1,1,0
PF00854,PTR2,POT family,1,1,1,1
PF11485,DUF3211,Protein of unknown function (DUF3211),1,1,1,0
PF00574,CLP_protease,Clp protease,1,0,0,0
PF03603,DNA_III_psi,DNA polymerase III psi subunit,1,0,0,0
PF01926,MMR_HSR1,50S ribosome-binding GTPase,1,0,0,0
PF00582,Usp,Universal stress protein family,1,0,0,0
PF13949,ALIX_LYPXL_bnd,ALIX V-shaped domain binding to HIV,2,0,0,0
PF03171,2OG-FeII_Oxy,2OG-Fe(II) oxygenase superfamily,1,0,0,0
PF00640,PID,Phosphotyrosine interaction domain (PTB/PID),1,0,0,0
PF00926,DHBP_synthase,"3,4-dihydroxy-2-butanone 4-phosphate synthase",1,1,0,0
PF02632,BioY,BioY family,1,0,0,0
PF12120,Arr-ms,Rifampin ADP-ribosyl transferase,1,0,0,0
PF00627,UBA,UBA/TS-N domain,2,0,0,0
PF03063,Prismane,Prismane/CO dehydrogenase family,1,1,0,0
PF10345,Cohesin_load,Cohesin loading factor,1,0,0,0
PF07109,Mg-por_mtran_C,Magnesium-protoporphyrin IX methyltransferase C-terminus,1,0,0,0
PF00588,SpoU_methylase,SpoU rRNA Methylase family,2,0,0,0
PF02909,TetR_C,"Tetracyclin repressor, C-terminal all-alpha domain",1,0,0,0
PF02782,FGGY_C,"FGGY family of carbohydrate kinases, C-terminal domain",1,0,0,0
PF02475,Met_10,Met-10+ like-protein,1,0,0,0
PF00296,Bac_luciferase,Luciferase-like monooxygenase,1,0,0,0
PF13714,PEP_mutase,Phosphoenolpyruvate phosphomutase,2,0,1,0
PF12925,APP_E2,E2 domain of amyloid precursor protein,1,1,1,0
PF03022,MRJP,Major royal jelly protein,1,0,1,1
PF02509,Rota_NS35,Rotavirus non-structural protein 35,1,1,1,0
PF00107,ADH_zinc_N,Zinc-binding dehydrogenase,1,1,0,0
PF09733,VEFS-Box,VEFS-Box of polycomb protein,1,0,0,0
PF02896,PEP-utilizers_C,"PEP-utilising enzyme, TIM barrel domain",1,0,0,0
PF00145,DNA_methylase,C-5 cytosine-specific DNA methylase,1,0,0,0
PF10502,Peptidase_S26,"Signal peptidase, peptidase S26",1,0,0,0
PF06090,Ins_P5_2-kin,Inositol-pentakisphosphate 2-kinase,1,0,1,0
PF02152,FolB,Dihydroneopterin aldolase,1,0,0,0
PF02203,TarH,Tar ligand binding domain homologue,1,0,0,0
PF02540,NAD_synthase,NAD synthase,1,1,1,0
PF05191,ADK_lid,"Adenylate kinase, active site lid",2,0,0,0
PF02634,FdhD-NarQ,FdhD/NarQ family,1,0,0,0
PF12706,Lactamase_B_2,Beta-lactamase superfamily domain,1,0,0,0
PF07517,SecA_DEAD,SecA DEAD-like domain,1,1,0,0
PF06840,DUF1241,Protein of unknown function (DUF1241),1,0,0,0
PF00308,Bac_DnaA,Bacterial dnaA  protein,1,0,1,0
PF07690,MFS_1,Major Facilitator Superfamily,1,0,0,0
PF04622,ERG2_Sigma1R,ERG2 and Sigma1 receptor like protein,2,0,0,0
PF14368,LTP_2,Probable lipid transfer,1,0,0,0
PF03738,GSP_synth,Glutathionylspermidine synthase preATP-grasp,1,1,1,0
PF03349,Toluene_X,Outer membrane protein transport protein (OMPP1/FadL/TodX),1,1,0,0
PF00450,Peptidase_S10,Serine carboxypeptidase,3,0,1,0
PF02018,CBM_4_9,Carbohydrate binding domain,2,0,0,0
PF00742,Homoserine_dh,Homoserine dehydrogenase,1,1,1,1
PF01928,CYTH,CYTH domain,1,0,1,0
PF07858,LEH,"Limonene-1,2-epoxide hydrolase catalytic domain",1,1,0,0
PF00532,Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of LacI family,1,1,0,0
PF06428,Sec2p,GDP/GTP exchange factor Sec2p,1,0,0,0
PF17167,Glyco_hydro_36,"Glycosyl hydrolase 36 superfamily, catalytic domain",2,2,0,0
PF03767,Acid_phosphat_B,"HAD superfamily, subfamily IIIB (Acid phosphatase)",1,1,0,0
PF01590,GAF,GAF domain,2,0,0,0
PF02752,Arrestin_C,"Arrestin (or S-antigen), C-terminal domain",1,0,0,0
PF15410,PH_9,Pleckstrin homology domain,1,0,0,0
PF13414,TPR_11,TPR repeat,1,0,0,0
PF13365,Trypsin_2,Trypsin-like peptidase domain,1,0,0,0
PF01965,DJ-1_PfpI,DJ-1/PfpI family,1,0,0,0
PF03702,AnmK,Anhydro-N-acetylmuramic acid kinase,1,1,0,0
PF03834,Rad10,Binding domain of DNA repair protein Ercc1 (rad10/Swi10),1,0,0,0
PF03644,Glyco_hydro_85,Glycosyl hydrolase family 85,1,0,0,0
PF18460,HetR_C,Heterocyst differentiation regulator C-terminal Hood domain,1,0,0,0
PF00957,Synaptobrevin,Synaptobrevin,1,0,0,0
PF00599,Flu_M2,Influenza Matrix protein (M2),1,0,0,0
PF06511,IpaD,Invasion plasmid antigen IpaD,1,1,0,0
PF02341,RcbX,RbcX protein,1,1,1,0
PF05096,Glu_cyclase_2,Glutamine cyclotransferase,1,1,0,0
PF00540,Gag_p17,gag gene protein p17 (matrix protein),1,0,0,0
PF02825,WWE,WWE domain,1,0,0,0
PF10480,ICAP-1_inte_bdg,Beta-1 integrin binding protein,1,0,0,0
PF10401,IRF-3,Interferon-regulatory factor 3,1,1,1,0
PF01075,Glyco_transf_9,Glycosyltransferase family 9 (heptosyltransferase),1,0,1,0
PF10250,O-FucT,GDP-fucose protein O-fucosyltransferase,2,1,0,0
PF03671,Ufm1,Ubiquitin fold modifier 1 protein,1,0,0,0
PF04252,RNA_Me_trans,Predicted SAM-dependent RNA methyltransferase,1,0,1,0
PF11477,PM0188,Sialyltransferase PMO188,1,0,0,0
PF04587,ADP_PFK_GK,ADP-specific Phosphofructokinase/Glucokinase conserved region,1,1,0,0
PF02028,BCCT,"BCCT, betaine/carnitine/choline family transporter",1,0,0,0
PF13513,HEAT_EZ,HEAT-like repeat,1,0,0,0
PF01896,DNA_primase_S,DNA primase small subunit,1,0,0,0
PF00593,TonB_dep_Rec,TonB dependent receptor,1,1,0,0
PF01099,Uteroglobin,Uteroglobin family,1,1,1,0
PF11308,Glyco_hydro_129,"Glycosyl hydrolases related to GH101 family, GH129",1,0,0,0
PF00630,Filamin,Filamin/ABP280 repeat,1,0,0,0
PF07717,OB_NTP_bind,Oligonucleotide/oligosaccharide-binding (OB)-fold,1,0,0,0
PF11495,Regulator_TrmB,Archaeal transcriptional regulator TrmB,1,0,0,0
PF00762,Ferrochelatase,Ferrochelatase,1,0,0,0
PF03492,Methyltransf_7,SAM dependent carboxyl methyltransferase,1,0,0,0
PF00377,Prion,Prion/Doppel alpha-helical domain,1,1,1,0
PF02170,PAZ,PAZ domain,1,0,0,0
PF13869,NUDIX_2,Nucleotide hydrolase,1,0,0,0
PF04675,DNA_ligase_A_N,DNA ligase N terminus,1,0,0,0
PF00362,Integrin_beta,Integrin beta chain VWA domain,1,1,1,1
PF11721,Malectin,Di-glucose binding within endoplasmic reticulum,1,0,0,0
PF02911,Formyl_trans_C,"Formyl transferase, C-terminal domain",1,0,0,0
PF05025,RbsD_FucU,RbsD / FucU transport protein family,1,0,0,0
PF02449,Glyco_hydro_42,Beta-galactosidase,1,0,0,0
PF00365,PFK,Phosphofructokinase,1,1,0,0