MR_no,CLINICAL,SPECIMEN,MICROSCOPIC FINDINGS,IMPRESSION,GROSS FINDINGS
FN16000080,right breast lump carcinoma.,biopsy of right breast lump.,received multiple grey white to grey brown linear cores measures 0.8 to 1 cm. entire tissue is processed.,section shows cores of breast tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
FN1700017,mass in right breast carcinoma breast.,biopsy from right breast.,received 3 grey white to grey brown linear cores 1 to 1.2cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged as cords nests and tubules. the cells have round to oval hyperchromatic nucleus with moderate atypia and scanty cytoplasm. stroma shows fibrosis hyalinisation and focal desmoplasia,biopsy from right breast :invasive ductal carcinoma grade 2.modified bloom richardson score 7 9tubule formation :3nuclear pleomorphism :2mitotic figures :2 7 9
FN1703934,known case of carcinoma breast multiple liver space occupying lesion metastasis.,biopsy from liver lesion.,received multiple grey white to grey brown linear cores measures 1 to 1.5cm. entire tissue processed.,linear cores of fibrous tissue harboring a neoplasm arranged as clusters and tubules. the neoplastic cells have hyperchromatic nuclei and moderate cytoplasm. lymphovascular emboli seen.,biopsy from liver lesion:invasive carcinoma suggestive of metastasis in a known case of carcinoma breast.
FN1704890,left breast retroareolar mass.,biopsy from left breast mass.,received 4 grey white linear cores measuring 0.5 to 1cm. entire tissue processed.,section shows multiple fragments of breast parenchyma having a neoplastic lesion arranged in cords nests trabecular and in tubules. the cells round to oval hyperchromatic to vesicular nuclei with prominent nucleoli and abundant eosinophilic cytoplasm. areas of fibrosis noted.,left breast core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
FN1707208,right breast mass.carcinoma breast lobular carcinoma.,right breast mass core biopsy.,received five grey white to grey yellow linear cores measuring 1 to 1.5cm. entire tissue processed.,section shows tumor cells in cords and occasional nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast mass core biopsy :suggestive of invasive carcinoma with lobular features grade 2. modified bloom richardson score is 6(3+2+1).
FN1707532,right breast lesion.,biopsy from right breast.,received multiple grey white to grey brown linear cores measuring 0.5 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters and islands. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. areas of necrosis seen.,invasive ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
FN1713378,left breast lump.,biopsy from left breast lump.,received 6 greywhite linear cores measuring 0.7 to 1cm. entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged in tubules clusters floating in lakes of mucin. the neoplastic cells have hyperchromatic nuclei and moderate cytoplasm.,biopsy from left breast lump:invasive carcinoma with mucinous areas biopsy from left breast.modified br score 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
FN1715063,carcinoma left breast.,biopsy from left breast.,received multiple grey white to grey brown linear cores measures 0.8 to 0.8cm. entire tissue processed.,section shows linear tissue cores harboring an infiltrative lesion arranged as nests sheets and focal glands. the individual tumor cells show increased nucleo cytoplasm ratio nuclear hyperchromasia pleomorphism and scant amount of vacuolated cytoplasm. the surrounding shows is composed fibricollagenous and adipose tissue and shows infiltration by lymphocytes plasma cells few eosinophils and neutrophils.,biopsy from left breast:invasive dictal carcinoma grade 2modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
FN1717819,carcinoma right breast postlesion in left breast carcinoma breast.,biopsy from left breast,received 5 grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue processed.,section shows cores of breast tissue with an invasive neoplasm in nests and cords. the cells show moderate eosinophilic neoplasm pleomorphic hyperchromatic nuclei and occasional cells shows nucleoli. stroma is demoplastic and myxoid with lymphocyte infiltrate,biopsy from left breast:invasive carcinoma nst grade 3modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism: 2mitotic figures : 2 8 9
FN1719118,right breast lump carcinoma breast,biopsy from right breast lump.,received 5 grey white linear cores measures 1 1.2cm. entire tissue processed.,section show multiple linear cores with tumor cells arranged in sheets and nests.the tumor cells have increased nuclear cytoplasmic ratio round nuclei and scant to moderate amount of cytoplasm. perivascular arrangement of tumor cells is seen .frequent mitotic figures are discerned.extensive necrosis is noted.,biopsy from right breast lump:invasive carcinoma nos nuclear grade 2
FN1802496,right breast lung mass with cyst and cleft carcinoma breast malignant,right breast core biopsy,received 5grey white to grey brown linear cores measures 1 1.2cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets and nests. individual tumor cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
FN1802638,right breast lump possibility of carcinoma breast.,right breast core biopsy.,received 4 grey white linear cores measures 0.8 1cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests . individual cells have hyperchromatic nucleus and moderate amount of cytoplasm.,right breast core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6 (3+2+1).
FN1804690,left breast lump possibility of carcinoma breast.,left breast lump.,received 3 grey white linear cores measures 0.7 to 1 cm entire tissue processed.,sections of linear cores of breast parenchyma is infiltrated by neoplastic cells arranged in tubules and cords. the lesional cells have round to irregular hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm. ductal carcinoma in situ component is seen.foci of calcification seen.,left breast lump biopsy :invasive ductal carcinoma grade 1.modified bloom richardson score : 5 9tubule formation : 1nuclear pleomorphism : 2mitotic activity : 2
FN1805388,known case of carcinoma right breast.,biopsy from right chest wall lesion.,received multiple grey white to grey brown linear cores measures 0.4 0.6cm. entire tissue processed.,section shows cores of fibroadipose tissue infiltrated by a lesion arranged in sheets nests. the cells have moderately pleomorphic hyperchromatic nuclei and moderate amount of cytoplasm. mitosis noted. stromal desmoplasia noted.,biopsy from right chest wall lesion:invasive carcinoma suggestive of recurrence in a known case of carcinoma breast.
FN1812840,lump left breast.,lumpectomy (wide local excision).,received single globular measures 4x4x3cm. skin measures 2x1cm. cutsurface grey white to grey brown areas of tumor measures 1x0.5cm.,section studied show breast parenchyma harboring an infiltrating lesion arranged in nests and sheets and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma is desmoplastic with ares of hemorrhage and necrosis.,left breast wide local excision. invasive ductal carcinoma grade 2.modified br score is 7 9tubule formation : 3 nuclear pleomorphism : 2mitotic figures : 2 ............ 7 9 .............tumor measures 1cm in greatest dimension.lymphovascular invasion and perineural invasion are not seen. ductal carcinoma in situ solid pattern noted. measures 0.3cm. all margins of resection (superior inferior medial lateral and deep) are free of tumor.
FN1813611,carcinoma left breast post nact.,left breast left modified radical mastectomy(post nact).,received in : formalinprocedure : left modified radical mastectomy post nact.laterality : left.total dimensions : medial to lateral 21 cm superficial to deep 4 cm. superior to inferior 12 cm.skin ellipse : 12 x 9 cm. nipple : normal scar surgical defect : absent.tumor : single.tumor size : 2 x 1.5 x 1 cm. location of tumor : retroareolar fibrotic lesion central quadrant. margins of tumor : illdefined. deep margin : 2cm.muscle : 2cm.adjacent breast : fibrofatty tissue. axillary tail : 11 x 6 x 2 cmsize of largest node : 2 x 1.5 x 1 cm.representative sections are submitted.,section from breast parenchyma showing residual tumor cells arranged in cords and nests. the cells have round nuclei prominent nucleoli and moderate eosinophilic cytoplasm. lymphovascular or perineural invasion is not identified. treatment related changes are seen.,left breast left modified radical mastectomy(post nact) :residual invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). tumor is located in the retroareolar region. tumor measures 2 cm in greatest dimensions. ductal carcinoma in situ is seen of cribriform and solid pattern with intermediate nuclear grade. lymphovascular invasion is not identified. perineural invasion is not identified. posterior resection margin is free of tumor. nipple and areola is unremarkable.lymph nodes:ten lymph nodes are identified negative for malignancy (0 10).pathological stage: ypt1cn0
FN1815927,left breast lump.,left breast lump biopsy.,received 4 grey white linear core measures 0.5 to 1cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in nests and tubules. the neoplastic cells show increased n:c ratio moderate eosinophilic cytoplasm pleomorphic hyperchromatic nuclei with few showing prominent nucleoli.,left breast lump biopsy :invasive carcinoma nst. grade ii.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
FN1816775,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in tubular pattern and in cords .the lining neoplastic cells show moderate cytoplasm moderately pleomorphic hyperchromatic nuclei.,biopsy from left breast lump. :invasive carcinoma nst. grade iimodified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
FN1901311,history of lumpectomy.left axillary lymph node.,biopsy from left axillary lymph node.,received multiple fragment cores measures 1.3 to 1.4cm. entire tissue processed.,section studied shows linear cores of lymphoid tissue harboring an invasive neoplasm arranged in glandular pattern trabeculae and nests. the lesional cells are round to polygonal with moderate eosinophilic cytoplasm pleomorphic hyperchromatic nucleus. few showing prominent nucleoli and intranuclear inclusion. occasional mitotic figures seen. interspersed are sheets of lymphoid population.,biopsy from left axillary lymph node:metastatic deposits of invasive carcinoma in a known case of carcinoma breast.
MR160000120,left breast lump carcinoma.,biopsy from left breast.,received 4 greywhite to greybrown linear cores measuring 1 to 1.5cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as tubules and islands neoplasm arranged. the meoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclear conspicuous nucleoli and moderate cytoplasm lymphovascular emboli seen.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 6 9 grade 2.tubules formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160000127,case of lump in left breast.,biopsy from left breast.,received 4 greywhite linear cores measuring 0.7 to 1cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters and sheets. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is elastotic.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160000140,left breast lump carcinoma.,trucut biopsy of left breast lump.,received 3 greywhite linear cores measuring 4.5 to 1.8 cm.,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets and nests.individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.few large bizarre forms are seen.,left breast lump core biopsy :invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+3+2).
MR160000142,carcinoma left breast(post 3nact).,left breast and axilla.,received in : formalin time of receipt at lab : 12:50pm 21 04 16.time to formalin procedure :mastectomy laterality : left total dimensions : medial lateral:22cm superficial deep:4.5cm superior inferior:17cm.skin ellipse :17x10cm.nipple :normal scar surgical defect : not seen.tumor : : single.tumour bed shows : grey white areas measuring 3 x 2 x 1.5 cm.distance to nearest separate tumor foci (when multiple )location of tumor : lower inner quadrant. margins of tumor : illdefined. deep margin : 2cm.muscle : present. adjacent breast : fibrofatty. total number of nodes : 17 (specify if sentinel nodes sent )size of largest node : 2.5x2x1cm.cut surface is greywhite.axillary tail : 6x5x2.5cm.,section shows no residual tumour. treatment related changes are seen including extensive areas of sclerosis fibrosis with compressed benign ductal elements focal areas of chronic inflammatory infiltration consisting of lymphocytes and plasma cells. areas of calcification present.,left breast and axilla left modified radical mastectomy (post nact) :no residual tumor seen. treatment related changes are present. lymphovascular invasion is not identified. perineural invasion is not identified. posterior resected margin is free of tumor.lymph nodes :one out of fifteen lymph nodes shows metastatic tumour deposit(1 15). size of the tumour focus measures 0.3 cm in greatest dimension. no extranodal extension is seen.pathological stage : ypt0n1a
MR160000145,right breast lump carcinoma.,biopsy from right breast.,received 3 greywhite linear cores measuring 1 to 1.5cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as tubules and cords. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic to vesicular nuclei with conspicuous nucleoli and moderate cytoplasm .probable lymphovascular emboli seen.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 6 9 grade 2.tubules formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160000165,left breast lump carcinoma.,biopsy from left breast lesion.,received 5 greywhite linear cores measuring 0.5 to 1cm. entire tissue processed.,linear cores of breast parenchyma exhibiting a neoplastic lesion arranged in nests tubules and islands consisting of ovoid cells demonstrating moderate atypia and eosinophilic cytoplasm. mitotic figures are discerned. intervening areas show desmoplastic stroma.,biopsy from left breast lesion :invasive ductal carcinomamodified br score is 6 9 grade 2.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR160000395,known case of carcinoma left breast. post bcs ct rt. lower defined lesion underlying the scar.,left breast lesion underneath the scar.,received 4 grey whit4e linear cores measures 0.5 1cm. entire tissue processed.,section shows linear cores of fibrofatty tissue with extensive areas of hyalinisation and histiocytes. no evidence of malignancy noted.,left breast lesion underneath the scar:shows treatment related changes. no evidence of invasive malignancy seen.
MR160000436,case of lump is right breast carcinoma right breast.,biopsy from right breast.,received 3 grey white to grey brown linear cores measuring 0.8 to 0.5cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. lymphovascular emboli seen,infiltrating ductal carcinoma biopsy from right breast.modified br score is 7 9 grade : 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160000531,hetrogenous irregular mass lesion in lateral aspect of right breast likely malignancy.,biopsy from right breast.,received 3 grey white to grey brown linear cores measuring 0.8 to 1cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters cords and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm probable. lymphovascular emboli seen. areas of necrosis seen.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160000532,left breast lump carcinoma.,biopsy from left breast.,received 3 grey white to grey brown linear core measuring 0.2 to 0.8cm. entire tissue processed.,linear core of breast parenchyma infiltrated by a neoplasm arranged as cords and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is fibrous.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160000675,right breast lump carcinoma.,biopsy from right breast.,received 5 grey white to grey brown linear core 0.5 to 1cm. entire tissue processed,linear cores of breast tissue infiltrated by a neoplasm arranged as clusters cells cords and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and vacuolated cytoplasm. the intervening stroma is desmoplastic.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160000790,carcinoma left breast.,left modified radical mastectomy.,breastreceived in : formalin procedure : mastectomy mrm. laterality : left.total dimensions : medial lateral:20cm. superficial deep:3cm. superior inferior:18cm.skin ellipse : 11x7cm. nipple : normal scar surgical defect : not seen.tumor : : single.tumour size : 2x1.5x1cm. location of tumor : upper outer quadrant. margins of tumor : ill defined. deep margin : 0.8cmmuscle : absent adjacent breast : fibrofatty total number of nodes : size of largest node : 1.5x1x0.5cm cut surface is greywhite.axillary tail : 5x4x3cm.,multiple sections from breast parenchyma show a neoplastic lesion arranged in nests cords and tubules.cells are having pleomorphic round to oval vesicular nuclei prominent nucleoli and moderate amount of cytoplasm.mitotic figures discerned.stroma shows lymphocytic infiltration.lympovascular invasion not identified.perineural invasion not identified.ductal caricnoma in situ not seen.,left breast left modified radical mastectomy: infiltrating ductal carcinoma grade 2. modified br score is 6 9.tubule formation: 02nuclear pleomorphism:02mitotic activity:02.tumor measures 2cm in greatest dimension.deep margin is 0.8cm away and free of tumor.lymphovascular invasion and perineural invasion are not identifiedductal carcinoma in situ not identified.nipple and areola show no significant histopathological change.eleven lymph nodes identified show reactive hyperplasia free from tumor(0 11).
MR160000856,mass in right breast carcinoma right breast.,biopsy from right breast mass.,received 3 greywhite linear core measuring 1x1.2cm.,section shows linear cores of breast parechyma harboring a lesion arranged as cords tubules nests and sheets. individual cells have hyperchromatic moderately pleomorphic nuclei inconspicuous nucleoli and moderate cytoplasm. stroma shows focal desmoplasia and dense lymphocytic infiltrate. lymphovascular invasion identified. perineural invasion is seen.,biopsy from right breast:invasive ductal carcinoma grade 2.mbr score is 6 (2+2+2). lymphovascular invasion identified. perineural invasion is seen.dcis (solid and cribriform type) present.
MR160000897,left breast mass carcinoma breast,biopsy from left breast mass,received 4 grey white linear cores measuring 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma with a neoplastic lesion arranged as sheets cords and tubules. individual cells have hyperchromatic nucleus with inconspicuous nucleoli. mitotic figures are discerned. lymphovascular invasion is not identified. ductal carcinoma in situ with comedonecrosis is seen.,biopsy from left breast mass: invasive ductal carcinoma. grade 2modified bloom richardson score:7 9tubule formation: 3nuclear anaplasia: 2mitotic figures: 2lymphovascular invasion is not identified.ductal carcinoma in situ with comedonecrosis is seen.
MR160000938,left breast lump carcinoma.,biopsy from left breast lump.,received 2 greywhite linear cores measuring 0.8 to 1 cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in tubules nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 5(2+2+1).
MR160000966,right breast lump carcinoma,biopsy from right breast.,received 4 grey white to grey brown linear cores measuring 0.5 to 1cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters cords and tubules. the neoplastic cells have hyperchromatic nuclei and moderate cytoplasm . lymphovascular emboli seen. the intervening stroma is desmoplastic.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 5 9 grade 1tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9
MR160000972,irregular mass in the left breast neoplastic,biopsy from left breast mass.,received four grey white to grey brown linear cores measuring 1 to 1.5 cm. entire tissue processed.,section shows cores of tissue infiltrated by diffuse sheets cords and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy : invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1)
MR160001039,multiple irregular lesion in right breast carcinoma.,a)biopsy from right breast.,received 6 grey white to grey brown linear core measuring 0.5 to 1cm. entire tissue processed.,a) section shows linear cores of breast tissue harboring a neoplastic lesion arranged as nested and vague acinar pattern. individual cells are oval to round with hyperchromatic pleomorphic nuclei prominent nucleoli and moderate cytoplasm. atypical mitosis noted. stroma shows desmoplasia lymphocytic infiltrate and myxoid change.,invasive carcinoma biopsy from right breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 lymphovascular invasion not seen.perineural invasion not seenductal carcinoma in situ not present.
MR160001176,right breast mass carcinoma breast.,biopsy from right breast.,received 5 grey white to grey brown linear cores measuring 1 to 1.5cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as sheets and islands. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,invasive carcinoma biopsy from right breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160001200,right breast mass carcinoma breast.,biopsy from right breast mass.,received 4 grey white to grey brown linear core measuring 0.5 to 1cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as nests and islands. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the nucleus are relatively eccentrically placed. the intervening stroma is desmoplastic.,invasive carcinoma with lobular features biopsy from right breast mass.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160001224,left breast solid cystic lesion carcinoma.,biopsy from left breast.,received multiple tiny grey white linear cores measuring 0.2 to 0.5cm. entire tissue processed.,linear cores of neoplasm arranged in papillary pattern bearing fibrovascular cores. these cores are lined by cubocolumnar epithelium exhibiting nuclear stratification and mild hyperchromasia and moderate cytoplasm.,papillary neoplasm biopsy from left breast.
MR160001246,left breast lump carcinoma.,biopsy from left breast.,received 3 grey white linear cores measuring 1 to 1.5cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords tubules and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyper chromatic nuclei and moderate cytoplasm. lymphovascular emboli seen.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 lymphovascular emboli seen.no ductal carcinoma in situ seen.
MR160001293,follow up case of carcinoma breast multiple liver lesions metastasis,biopsy from liver carcinoma breast.,resceived 4 grey white to grey brown linear cores measuring 0.6 to 0.9cm,section shows linear cores of liver parenchyma harboring a lesion arranged in tubules and cords. the cells are ovoid with moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. atypical mitotic figures are discerned .stroma shows desmoplasia with areas of hemorrhage and necrosis.,metastatic carcinoma in a known case of carcinoma breast biopsy from liver
MR160001338,largr irregular left breast mass.,biopsy from left breast.,received 3 grey white to grey brown linear cores measuring 0.4 to 0.7cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a lesion arranged in sheets and nests. the cells are ovoid with moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. atypical mitotic figures are discerned. stroma shows desmoplasia with mild inflammatory infiltrate.focus of high grade ductal carcinoma (comedo pattern) seen.,invasive ductal carcinoma biopsy from left breast.modified br score is 8 9 grade 3tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 focus suggestive of high grade comedo ductal carcinoma in situ seen.
MR160001403,left breast lunp carcinoma.,biopsy from left breast.,received 3 grey white linear cores measuring 1 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters cords and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. no lymphovascular emboli seen. no ductal carcinoma in situ seen.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160001415,left breast lunp carcinoma.,biopsy from left breast.,received 3 grey white linear cores measuring 1 to 1.5cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords islands. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160001483,mass right breast carcinoma.,biopsy from right breast.,received 6 grey white linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a lesion arranged as tubules floating in a mucinous background. the cells are ovoid with moderate amount of eosinophilic cytoplasm hyperchromatic nucleus and inconspicuous nucleoli. atypical mitotic figures are discemed .extracellular mucinous pools are noted. stroma shows desmoplasia and mild inflammatory infiltrates.,invasive muciuous carcinoma biopsy from right breast.modified br score is 6 9 grade 2tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR160001506,mass right breast carcinoma,biopsy from right breast.,received 4 grey white to grey brown linear cores measuring 1 to 1.3cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a lesion arranged in sheets tubules and cords.the cells are ovoid with moderate amount of cytoplasm hyperchromatic nucleus and inconspicuous nucleoli.atypical mitotic figures are discerned. stroma shows desmoplasia and mild inflammatory infiltrate.areas of hemorrhage seen.,invasive ductal carcinoma biopsy from right breast.modified br score is 6 9 grade 2tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR160001507,right breast mass carcinoma.,biopsy from right breast.,received 4 grey white to grey brown linear core measuring 0.9 to 1.3cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a lesion arranged in sheets and nests. the cells are ovoid with moderate amount of cytoplasm hyperchromatic nucleus and conspicuous nucleoli in few. stroma shows desmoplasia and inflammatory infiltrate. atypical mitotic figures are discerned. areas of hemorrhage and necrosis seen.,invasive carcinoma biopsy from right breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 lymphovascular emboli seen.
MR160001509,left breast mass. fnac:infiltrating ductal carcinoma,biopsy from left breast.,received 5 grey white to grey brown linear cores measuring 0.8 to 1cm. entire tissue processed.,section show linear cores of tissue with a lesion arranged in cords nests and sheets. individual cells are moderately pleomorphic with hyperchromatic nuclei. inconspicious nucleoli moderate amount of eosinophilic cytoplasm. stroma is fibrous with inflammatory infiltrate and bland stromal cells.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160001562,usg guided biopsy from left breast carcinoma breast.,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 0.7 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters and islands. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. areas of necrosis seen. the intervening stroma is desmoplastic.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160001599,left breast lesion carcinoma.,biopsy from left breast.,received 4 grey white to grey brown linear core measuring 1 to 1.3cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters cords and cords. the cells have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma shows lymphocytic inflammatory cell infiltrate.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160001628,right breast lesion carcinoma right breast.,biopsy from right breast.,received 3 grey white to grey brown linear cores measuring 0.5 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords nests and strands. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160001647,known case of carcinoma breast.,biopsy from right cervical node.,received 5 grey whitelinear cores measures 0.3 to 0.8cm. entire tissue processed.,section show linear cores of fibrocollagenous tissue with an infiltrating lesion arranged in sheets having round to oval moderate pleomorphic hyperchromatic nuclei and moderate amount of cytoplasm. large areas of necrosis noted. mitotic figures discerned.,biopsy from right cervical node:suggestive of metastatic deposits in a known case of carcinoma breast.
MR160001685,left breast lesion with likely chest wall infiltration.outside fnac carcinoma.,biopsy from left breast.,received 5 grey white to grey brown linear cores measuring 1 to 1.4cm. entire tissue processed.,linear cores of fibrous tissue incorporating a neoplasm arranged as islands and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm.,invasive ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160001737,carcinoma right breast.,biopsy from right breast.,received 3 grey white to grey brown linear cores measuring 1 to 1.3cm. entire tissue processed.,linear cores of breast parenchyma incorporating a neoplasm arranged as islands and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have variably pleomorphic vesicular nuclei with conspicuous nucleoli and abundant foamy cytoplasm. the intervening stroma is fibrous.,invasive carcinoma biopsy from right breast.modified br score is 8 9 grade 2tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR160001742,left breast lesion fnac duct cell carcinoma.,biopsy from left breast.,received 5 grey white to grey brown linear cores measuring 1 to 1.3cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged predominantly in trabecular pattern. there cells have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is fibrous.,invasive carcinoma biopsy from left breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160001768,mass in left breast carcinoma breast.,biopsy from left breast.,received 4 grey white to grey brown linear core measuring 0.5 to 0.7cm. entire tissue processed.,section studied shows linear cores of breast tissue harboring a lesion arranged in diffuse sheets. individual cells have abundant eosinophilic cytoplasm and pleomorphic nuclei. mitotic activity discerned. stroma is fibrous with bland stromal cells and lymphoplasmacytic infiltrate.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). ductal carcinoma in situ of cribriform pattern with intermediate nuclear grade is seen.
MR160001773,lumpectomy left breast.,a) wide local excision.b) revised lateral margin.c) sentinel lymph nodes.,a) received fibrofatty tissue measuring 3.5x5x3.5cm skin ellipse 2.5x1cm.cut surface shows illdefined greywhite area measuring 1.3x0.7x1cm.located at the following distances from respective margins: superior margin 1.8cm.inferior margin 1.3cm.medial margin 2.5cm.lateral margin 0.7cm.deep margin 1.5cm.distance of ill defined greywhite area from skin is 1cm.b) received fibrofatty tissue measuring 5x1x0.5cm.one surface inked.entire tissue is processed.c) received multiple fibrofatty tissue measuring 3x2x1cm.isolated 2 lymph nodes one measuring 1.5x1x0.5cm.cut surface is unremarkable.another measuring 1x1x0.5cm.cut surface is fatty infiltration.dissected 4 lymph nodes.,a) wide local excision: breast conservative surgery.tumor bed:tumor is composed pleomorphic cuboidal cells with hyperchromatic nucleus and eosinophilic cytoplasm.invasive ductal carcinoma tubular pattern.grade: tubular formation 60 2 nuclear pleomorphism 5 10 2 mitotic figures 5 10 1mbr score is 5 9nuclear grade i.ductal carcinoma in situ: not present.lymphovascular invasion: not present.resected margins:superior margin free of tumor.inferior margin free of tumor.medial margin free of tumor.lateral margin free of tumor.deep margin free of tumor.b) revised lateral margin:shows fibrofatty tissue free of tumor.c) sentinel lymph nodes:4 nodes no deposits of tumor.,wide local excision with lateral invasive ductal carcinoma.maximum dimension of the tumor 1.3x1x0.7cm. grade i.ductal carcinoma in situ: not present.lymphovascular invasion:not present.all resected margins are free of tumor.additional lateral margins:free of tumor.sentinel lymphnodes 4 nodes.no deposits of tumor.
MR160001834,known case of carcinoma breast completed treatment and on tamoxifen since one year,total abdominal hysterectomy with bilateral salpingoopherectomy specimen,uterus dimensions : midline fundal serosa to ectocervix : 10cmmaximum intercornual : 6cmmaximum anterior to posterior : 3cmcervix dimensions :3.5x2cm elongated. cut section shows cyst measuring 1x1x0.5cmvaginal cuff : absentright ovary : present 2.5x1x1cmleft ovary : present 2.5x2x1cm right fallopian tube : present 4cm left fallopian tube : present 3.5cm right parametrium : 3.5x2x1cmleft parametrium : 3x2x1cmendometrium description : dilated cavity shows a polyp confined to endometrial canal measures 3x3x2.5cmendometrial thickness :0.3cm myometrium depth :3cminvolvement of myometrium by tumor : no myometrial invasion seen grosslymyometrial appearnance : no adenomyosis leiomyoma : yes single intramural measures 1x1x1cm lower uterine segment : unremarkable,section from the endometrium shows a polypoidal lesion with dilated cystic spaces lined by cuboidal to flattened epithelium and a loose fibrous stroma with congested vessels. myometrium shows adenomyosis.cervix shows nabothian cyst.bilateral ovaries are unremarkable bilateral tubes show hydrosalpinx.,total abdominal hysterectomy with bilateral salpingoopherectomy specimenbenign endometrial polypno evidence of malignancy in the material submitted.
MR160001851,right breast lesion carcinoma.,right breast lesion biopsy.,received 4 grey white to grey brown linear core measuring 0.9 to 1.1cm. entire tissue processed.,section shows linear cores of tissue showing breast parenchyma with lesion arranged in tubules cords. individual cells are moderately pleomorphic with round to oval hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. stroma is fibrous with bland stromal cells and lymphocytic infiltrate.,right breast lesion biopsy :invasive ductal carcinoma grade iimodified br score is 6 9tubule formation 3nuclear pleomorphism 2mitoses 1
MR160001893,right breast lesion carcinoma right breast.,biopsy from right breast.,received 4 grey white linear core measuring1 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged as linear cords and indian file pattern. the tumor cells have hyperchromatic pleomorphic round to oval nuclei with scanty cytoplasm.lymphovascular invasion present.,invasive carcinoma suggestive of ductal origin biopsy from right breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 lymphovascular invasion present.
MR160001919,left breast irregular lesion outside fnac possibility of carcinoma.,biopsy from left breast.,received 3 grey white to grey brown linear cores measuring 1 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism hyperchromasia and have moderate cytoplasm. crush artefact seen. focus of high grade comedo ductal carcinoma in situ noted.,invasive ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism 2mitotic figures : 2 7 9 focus of high grade dcis discerned.
MR160001954,a) wide local excision frozen specimen.b) revised deep margin.c) revised inferior margin.d) left axillary lymph node dissection (level i ii).,a) received lumpectomy specimen measuring 5.5x3.8x3cm greywhite nodule measuring 0.3x0.3x0.2cm.skin ellipse with scar measures 4.2x1.6cm.linear scar measuring 4cm. irregular greywhite area fibrosis measuring 1.5x1x1cm located at the following distance from respective margins: superior margin 1.2cm.inferior margin 0.5cm.medial margin 1.5cm.lateral margin 1.8cm.deep margin 0.6cm.b) received fibrofatty tissue measuring 2.5x1.5x1cm. entire tissue processed.c) received fibrofatty tissue measuring 3.5x2.5x1cm. entire tissue processed.d) received multiple fibrofatty tissue altogether measuring 7x5.5x2cm.largest lymph node measuring 1.5x1x0.5cm. cut surface shows greywhite necrotic area.dissected 12 nodes.,a) wide local excision frozen,tumor site : previous scar site residual tumor present shows invasive ductal carcinoma.grade : tubular formation 40 : 2nuclear pleomorphism : 2mitotic figures 6 10 : 2 6 9 mbr score is 6 9 nuclear grade ii.lymphovascular invasion : indeterminate.dcis : not present.surrounding tumor fibrosis necrosis and inflammatory cells are present.resected margins: superior margin : free of tumor.inferior margin : few ducts are showing atypical hyperplasia.medial margin : free of tumor.lateral margin : free of tumor.deep margin : ducts show atypical hyperplasia.b) revised deep margin : the section shows muscle bundle free of tumor.c) revised inferior margin: fibrofatty tissue free of tumor.d) left axillary lymph node dissection (level i ii):2 nodes show metastatic deposits of tumor out of 12 nodes.,wide local excision with revised deep margin and skin nodule area with invasive ductal carcinoma.maximum dimension is 1.5x1cm.nuclear grade ii.dcis : not present.lymphovascular invasion : indeterminate.resected margins: superior margin : free of tumor.inferior margin : few ducts are showing atypical hyperplasia.medial margin : free of tumor.lateral margin : free of tumor.deep margin : ducts show atypical hyperplasia.revised inferior margin : free of tumor.revised deep margin : free of tumor.lymph nodes: 2 nodes show metastatic deposits of tumor out of 12 nodes.
MR160001990,right breast lesion carcinoma right breast.,biopsy from right breast.,received 4 grey white linear cores measuring 0.4 to 0.8cm. entire tissue processed.,section shows linear cores of tissue showing breast parenchyma harboring a lesion arranged in tubules and sheets. individual cells are moderately pleomorphic with round to oval hyperchromatic nuclei inconspicous nucleoli and moderate amount of cytoplasm. stroma is fibrous with bland stromal cells. areas of necrosis noted.,invasion ductal carcinoma.modified br score is 6 9 grade ii.tubule formation :3nuclear pleomorphism :2mitotic figures : 1 6 9
MR160002027,right breast lump carcinoma,biopsy from right breast lump.,received 5 grey white to grey brown linear core measuring 0.6 to 1 cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged as tubules cords and nests of ovoid to columnar cells with hyperchromatic pleomorphic nuclei and moderate to abundant eosinophilic cytoplasm. adjacent breast shows desmoplasia. ductal carcinoma in situ not present. lymphovascular invasion not identified. perineural invasion seen.,invasive ductal carcinoma biopsy from right breast lump.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures (7 8 10hpf) : 2 7 9 lymphovascular invasion not identified.perineural invasion seen.
MR160002033,left breast mass carcinoma breast.,biopsy from left breast.,received 5 grey white to grey brown linear core measuring 0.8 to 1.1cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords and tubules and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. probable lymphovascular emboli seen.,invasive ductal carcinoma biopsy from left breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160002044,complex cystic lesion right breast carcinoma right breast.,biopsy from right breast.,received 4 grey white to grey brown linear core measuring 0.4 to 0.6cm. entire tissue processed.,linear cores of breast parenchyma showing a few benign ducts admixed with haemorrhagic focus. an occasional dilated duct seen.,benign breast disease biopsy from right breast.no evidence of malignancy in the cores submitted.
MR160002103,right breast lump carcinoma,biopsy from right breast lump.,received 5 grey white to grey brown linear core measuring 0.6 to 0.8 cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged as tubules cords and sheets. individual tumor cells are round to oval with hyperchromatic nuclei few with prominent nucleoli and moderate cytoplasm. lymphovascular invasion not identified.ductal carcinoma in situ present. adjacent breast shows apocrine metaplasia.,invasive ductal carcinoma biopsy from right breast lump.modified br score is 6 9 grade 2tubule formation : 2nuclear pleomorphism : 2mitotic figures (7 8 10hpf) : 2 6 9 lymphovascular invasion not identified.ductal carcinoma in situ seen.
MR160002111,right breast carcinoma,biopsy from right breast.,received 5 grey white to grey brown linear core measuring 0.9 to 1.2 cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords and tubules comprising of round to oval cells with hyperchromatic nuclei inconspicuous nucleoli and moderate cytoplasm. extensive ductal carcinoma in situ present. lymphovascular invasion identified. perineural invasion not present.,invasive carcinoma suggestive of ductal origin. biopsy from right breast.modified br score is 5 9 grade 1tubule formation : 2nuclear pleomorphism : 2mitotic figures (11 12 10hpf) : 1 5 9 extensive ductal carcinoma in situ (solid cribriform and papillary) noted.lymphovascular invasion present.
MR160002112,right breast lump carcinoma.,biopsy from right breast lump.,received 4 grey white to grey brown linear cores measuring 0.8 to 1cm. entire tissue processed.,linear cores of predominantly necrotic tisue incorporating small volume of neoplasm arranged as islands and sheets. the neoplastic cells exhibit moderate nuclear pleomorphic have hyperchromatic nuclei and moderate cytoplasm.,invasive ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160002113,left breast lump carcinoma,biopsy from left breast lump.,received 4 grey white to grey brown linear core measuring 1 to 1.2 cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in tubules and nests. the cells have hyperchromatic pleomorphic nucleoli few with prominent nucleoli and moderate cytoplasm. lymphovascular invasion present. ductal carcinoma in situ not seen.,invasive ductal carcinoma biopsy from left breast.modified br score is 6 9 grade 2tubule formation : 2nuclear pleomorphism : 2mitotic figures (11 12 10hpf) : 2 6 9 lymphovascular invasion present.
MR160002118,left breast hard lumps carcinoma.,biopsy from left breast lump.,received 6 grey white to grey brown linear cores measuring 0.6 to 1.2cm. entire tissue processed.,section show linear cores of tissue harboring a neoplastic lesion arranged in tubules and cords. individual cells are pleomorphic with round to oval hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. stroma is fibrous with bland stromal cells and extensive lymphocytic infiltrate. areas of hyalinisation and hemorrhage seen.,invasive ductal carcinoma biopsy from left breast.modified br score is 8 9 grade 3tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR160002120,right breast carcinoma,biopsy from right breast.,received 4 grey white linear core measuring 1 to 1.2 cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged as diffuse sheets.the tumor cells have round to oval hyperchromatic pleomorphic nuclei few with prominent nucleoli and moderate cytoplasm.stroma shows lymphocytic infiltrate. adjacent breast shows areas of fibrosis. ductal carcinoma in situ not present. lymphovascular incasion not identified. perineural invasion seen.,invasive ductal carcinoma biopsy from right breast.modified br score is 8 9 grade 3tubule formation : 3nuclear pleomorphism : 2mitotic figures (11 12 10hpf) : 3 8 9 lymphovascular invasion not identified.perineural invasion seen.
MR160002147,left breast lump carcinoma.,biopsy from left breast.,received 4 grey white linear core measuring 0.7 to 1.1cm. entire tissue processed.,section show cores of breast paranchyma harboring a lesion arranged in diffuse sheets and cords displaying round to oval hyperchromatic to vesicular nuclei prominent nucleoli and ill distinct cytoplasmic borders. peri neural invasion identified.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 lymphovascular invasion not identified.perineural invasion identified.ductal carcinoma in situ not identified.
MR160002201,left breast lump carcinoma.,biopsy from left breast.,received 3 grey white to grey brown linear core measuring 0.8 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a lesion arranged in sheets and nests. the cells are ovoid having moderate amount of cytoplasm vesicular nuclei and prominent nucleoli. atypical mitotic figures are discemed. stroma shows desmoplasia with mild inflammatory infiltrate. areas of hemorrhage and necrosis seen.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160002211,left breast lump carcinoma.,biopsy from left breast lump.,received 5 grey white to grey brown linear core measuring 0.4 to 0.7cm. entire tissue processed.,section show liner cores of breast paranchyma monomorphic cells with round to ovoid nuclei arranged as focal micropapillae and cribriform pattern with mild atypia. the surrounding stroma is desmoplastic with areas of necrosis. no invasion seen.,atypical ductal hyperplasia with associated ductal carcinoma in situ.
MR160002213,left breast lump carcinoma.,biopsy from left breast.,received 3 grey white linear core measuring 0.6 to 0.9cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is fibrous.,invasive ductal carcinoma with lobular features biopsy from right breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160002232,left breast lump carcinoma.,biopsy from left breast.,received 4 grey white to grey brown linear core measuring 0.6 to 0.7cm.entire tissue processed.,linear cores of haphazardly arranged elongted ducts lined by cubiocolumnar cells. mild nuclear atypia seen. the intervening stroma is mildly sclerotic.,suggestive of microglandular adenosis left breast.
MR160002256,right breast lump carcinoma.,biopsy from right breast.,received 5 grey white to grey brown linear cores measuring 0.7 to 1cm.entire tissue processed.,linear cores of breast parenchyma showing foci of calcification and high grade ductal carcinoma in situ . also included are normal benign ducts.,high grade ductal carcinoma in situ (comedo and solid pattern) biopsy from right breast.
MR160002258,small 2x2cm right breast lump.,biopsy from right breast.,received 4 grey white linear cores measuring 0.4 to 1cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. crush artifacts seen.,invasive ductal carcinoma biopsy from right breast lump.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160002300,mass in left breast carcinoma breast.,biopsy from left breast.,received 3 grey white to grey brown linear core measuring 0.5 to 1cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged in sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. atypical mitotic figures are discerned. stroma shows desmoplasia with areas of hemorrhage and necrosis.,invasive ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160002316,mass in right breast carcinoma breast.,biopsy from right breast mass.,received 3 grey white to grey brown linear core measuring 0.7 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a lesion arranged in sheets and nests. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. atypical mitotic figures are discerned. stroma shows desmoplasia with areas of hemorrhage and necrosis.,invasive ductal carcinoma biopsy from right breast mass.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160002405,larger left breast lumps phyllodes carcinoma.,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 1 to 1.2cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as islands sheets and in clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. a few of the cells have clear cytoplasm. foci suggestive of ductal carcinoma in situ noted.,invasive carcinoma biopsy from left breast.
MR160002457,case of left carcinoma breast.,a) wide excision lumpectomy.b) revised superior margins.c) re revised superior margins.d) left axillary dissection lymph node.,a) received lumpectomy specimen measures 10x7x3cm overlying skin measures 6x2cm.irregular grey white fibrotic areas seen measures 2x1x0.8cm. located at the following distances from the respective margins: superior margin 2cminferior margin 1.8cmmedial margin 1.1cmlateral margin 1.5cmdeep margin 0.9cmb) received single fibrofatty tissue with one surface inked measures 5x1.5x0.6cm.c) received single fibrofatty tissue measures 3x2x0.5cm with one surface inked.d) received single fibrofatty tissue measures 8x7.2x2cm largest lymph node measures 1.6x1.4x0.7cm.16 lymph nodes isolated.,a) tumor bed: shows fibrotic necrotic inflammatory cells foreign body giant cells and ducts show epithelial hyperplasia atypical hyperplasia and intraductal papillomatosis. there is no evidence of malignancy.resected margin superior margin shows atypical ductal hyperplasia.inferior margin free of tumor.medial margin free of tumor.deep margin free of tumor.b) revised superior margin two ducts are present showing ductal carcinoma in situ solid type low grade.no evidence of invasive carcinoma.c) re revised superior margin the section shows dilated ducts with epithelial hyperplasia free from the tumor.d) left axillary lymph nodes : 1 node shows metastatic deposits of viable tumor invasive ductal carcinoma out of 16 nodes.,wide excision with revised superior margin and axillary nodes.a) wide excision lumpectomy :atypical hyperplasia.epithelial hyperplasia with fibrosis necrosis and foreign body giant cells.no evidence of invasive carcinoma.resected margins inferior medial lateral and deep margin free of tumor.b) revised superior margins :show 2 ducts with ductal carcinoma in situ.c) re revised superior margins : free from the tumor.d) left axillary dissection lymph nodes :1 node shows metastatic deposits of viable tumor.invasive ductal carcinoma out of 16 nodes.perinodal spread is not present.
MR160002532,mass in left breast carcinoma breast.,biopsy from left breast.,received 5 grey white to grey brown linear cores measuring 0.5 to 1cm.entire tissue processed.,linear cores of breast parenchyma incorporating solid ductal carcinoma in situ. also noted is comedo ductal carcinoma in situ focus. no invasive component is evident in the cores submitted.,high grade ductal carcinoma in situ( solid comedo cribriform pattern) biopsy from left breast.an adjacent invasive focus cannot be excluded.
MR160002540,hypoechoic lesion in left breast carcinoma breast fibrosis.,biopsy from left breast.,received 3 grey white to grey brown linear cores measuring 1 to 1.5cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters and tubules. the neoplastic cells have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is fibrous.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 4 9 grade 1tubule formation : 1nuclear pleomorphism : 2mitotic figures : 1 4 9
MR160002577,mass in left breast carcinoma breast.,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 0.6 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters and islands. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate to abundant cytoplasm. the intervening stroma is fibrous.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160002611,right breast lump carcinoma.,biopsy from right breast.,received 4 grey white to grey brown linear cores measuring 0.4 to 0.6cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters and cords. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is fibrous.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160002643,mass in left breast carcinoma breast.,biopsy from left breast.,received 3 grey white to grey brown linear cores measuring 0.6 to 1.1cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters cords and sheets. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is fibrous.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160002721,left breast mass carcinoma.,biopsy from left breast.,received 4 grey white to grey brown linear core measuring 1.2 to 1.3cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters tubules and islands. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160002731,duct ectasia in left breast papilloma ductal carcinoma in situ.,biopsy from left breast.,received 4 grey white linear cores measuring 0.3 to 0.4cm.entire tissue processed.,linear cores of breast parenchyma showing occasional benign ducts. the intervening stroma is fibrous.,benign breast tissue biopsy from left breast.no ductal carcinoma in situ.no evidence of malignancy
MR160002739,mass in left breast carcinoma breast.,biopsy from left breast lesion.,received multiple greywhite linear cores measuring 1 to 1.5cm.entire tissue is processed.,linear cores of breast parenchyma with diffuse sheets of round to oval cells with hyperchromatic nuclei moderate nuclear pleomorphism and abundant intensely eosinophilic cytoplasm.occasional mitotic figures is seen.there is intense desmoplasia of the stroma with moderately dense lymphocytic infiltrate.,biopsy from left breast:poorly differentiated carcinoma. ductal
MR160002783,mass in left breast carcinoma breast.,biopsy from left breast.,received 3 grey white to grey brown linear cores measuring 0.7to 1.3cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters cords and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. probable lymphovascular emboli seen. no ductal carcinoma in situ noted.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160002786,mass in left breast carcinoma breast.,left breast core biopsy.,received 3 grey white to grey brown linear core measuring 0.6 to 0.7cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged as cords tubules and nests. individual tumor cells have hyperchromatic pleomorphic round to oval nuclei with moderate cytoplasm. areas of hemorrhage seen. stroma shows desmoplasia.,left breast core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 7(3+2+2).
MR160002804,mass in right breast carcinoma breast.,biopsy from right breast,received 3 grey white liner cores measuring 0.7 to 1.3 cm. entire tissue processed.,linear cores of breast parenchyma incorporating a neoplasm arranged as tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclear and moderate cytoplasm. lymphovasicular emboli seen.,infiltrating ductal carcinoma biopsy form right breast.modified br score is 5 9 grade 2tubular formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9
MR160002825,mass in left breast carcinoma breast.,biopsy from left breast.,received 3 grey white to grey brown linear core measuring 0.5 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei and conspicuous nucleoli and moderate cytoplasm. probable lymphovascular emboli seen.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160002844,left breast lump carcinoma,left breast core biopsy.,received 4 grey white to grey brown linear core measuring 0.7 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged as sheets tubules and nests. individual tumor cells have hyperchromatic pleomorphic nuclei with moderate cytoplasm. ductal carcinoma in situ solid type with comedonecrosis present.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160002891,gynecomastia of left breast glandular tissue carcinoma.,biopsy from left retroareolar breast tissue.,received 3 grey white linear cores measuring 0.7 to 1cm.entire tissue processed.,section shows cores of breast tissue showing proliferation of ducts lined by cuboidal epithelium with periductal stromal fibrosis and mild lymphocytic infiltrate. no atypia is seen.,left breast core biopsy :features are suggestive of gynecomastia.
MR160002942,right breast lump carcinoma.,biopsy from right breast lump.,received multiple greywhite linear cores measuring 1 to 1.3cm.entire tissue is processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged as nests cords and tubules of moderately pleomorphic nuclei and moderate cytoplasm few cells show prominent nucleoli.there are atypical mitoses .stroma shows periductal lymphoid aggregates and desmoplasia.,biopsy of right breast:invasive ductal carcinoma grade 2.mbr score is 7 9.tubule formation :3nuclear pleomorphism:2mitotic figures :2
MR160002944,left breast mass with axillary lymph node carcinoma.,biopsy from left breast.,received 4 grey white linear cores measuring 1 to 1.2cm.entire tissue processed.,section from the linear cores show breast paranchyma harboring a lesion with cells arranged in nests tubules and trabecular pattern. cells have moderate to scanty cytoplasm with round to oval hyperchromatic nuclei. ductal carcinoma in situ component is seen.,invasive ductal carcinoma.modified br score is 6 9 grade 2tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 ductal carcinoma in situ present.
MR160002954,left breast lump carcinoma,biopsy from left breast lump.,received 4 grey white linear core measuring 0.6 to 1.1cm. entire tissue processed.,section shows linear cores of breast tissue infiltrated by neoplastic lesion arranged in sheets. individual cells are moderately pleomorphic with round to oval hyperchromatic nuclei inconspicuous nucleoli and moderate amount of cytoplasm. stroma is fibrous with bland stromal cells. mitotic figures discerned.,left breast lump core biopsyinvasive ductal carcinoma grade 2.modified bloom richardson score is 7 (3+2+2)
MR160002962,mass right breast,biopsy from right breast mass.,received 2 grey white to grey brown linear cores measuring 1.1 to 1.2cm,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets nests and cords.individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast mass core biopsy : invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160002992,left breast lump carcinoma.,a) biopsy from left breast lump.b) biopsy from liver lesion.,a) received multiple grey white to grey brown linear cores measuring 1 to 1.2cm.entire tissue is processed.b) received 4 grey white to grey brown linear core measuring 0.7 to 1cm.entire tissue processed.,a) linear cores of breast parenchyma exhibiting a neoplastic lesion arranged in sheets nests and tubular configuration lined by cuboidal to ovoid cells demonstrating moderate nuclear pleomorphism and eosinophilic cytoplasm.mitotic figures are discerned.intervening areas show fibrocollagenous stroma.b) linear cores of liver parenchyma exhibiting a neoplastic lesion arranged in nests and islands consisting of ovoid to cuboidal cells demonstrating moderate atypia and eosinophilic cytoplasm amidst prominent areas of necrosis.,a) biopsy from left breast lump:invasive carcinoma grade ii.tubule formation 2nuclear pleomorphism 2mitotic figures 2. mbr score is 6 9 b) biopsy from liver lesion :metastatic carcinoma most likely from breast.suggest ihc.
MR160003012,right breast lump carcinoma.,biopsy from right breast.,received 4 grey white to grey brown linear core measuring 0.7 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged as nests and sheets. the tumor cells have round to oval hyperchromatic pleomorphic nuclei and moderate cytoplasm. ductal carcinoma in situ (solid type) present.,invasive ductal carcinoma biopsy from right breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 ductal carcinoma in situ (solid type) present.
MR160003068,left breast lump carcinoma.,biopsy from left breast.,received 4 grey white linear core measuring 0.7 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged as nests cords and tubules. the tumor cells have round to oval hyperchromatic pleomorphic nuclei inconspicuous nucleoli and moderate cytoplasm. atypical mitotic figures discerned.,invasive ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 ductal carcinoma in situ (solid type) present.
MR160003075,left breast lump carcinoma.,biopsy from left breast.,received 3 grey white to grey brown linear cores measuring 0.7 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged as solid sheets and nests. the tumor cells have round to oval hyperchromatic pleomorphic nuclei with moderate to abundant cytoplasm.,invasive ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160003136,known case of ductal carcinoma in situ bilateral breasts post op 1month.,biopsy from right breast lesion.,received multiple grey white to grey brown linear cores measuring 1 to 1.2cm.entire tissue is processed.,linear cores of breast parenchyma exhibiting focal areas of demonstrating aggregates of lymphocytic infiltrate macrophages and giant cells.there are areas of fibrosis.hyalinisation noted focally.,biopsy from right breast lesion : foreign body granulomata.no evidence of malignancy. in the material submitted.
MR160003218,right breast lump carcinoma.,biopsy from right breast lump.,received 4 grey white linear cores measuring 0.8 to 1cm.entire tissue processed.,section shows linear cores of breast parenchyma with extensive areas of sclerosis occasional areas of nests and tubules lined by cells have scanty cytoplasm with round to oval hyperchromatic nuclei with inconspicuous nucleoli.,suspicious for malignancy right breast lump.suggest excision biopsy for evaluation.
MR160003229,right breast lump carcinoma.,biopsy from right breast.,received 4 grey white to grey brown linear core measuring 1 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma exhibiting a neoplastic lesion arranged as tubules and nests consisting cuboidal to ovoid cells demonstrating moderate atypia and pale eosinophilic cytoplasm in a desmoplastic stroma. few papillae lined by cells with clear cytoplasm are noted.,biopsy from right breast : ductal papillary invasive carcinoma.modified br score is 5 9 grade 1tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9
MR160003232,known case of carcinoma right breast post modified radical mastectomy.right chest lesion recurrence.,chest wall recurrence biopsy.,received 4 grey white lineal core measures 0.5 to 1 cm. entire tissue processed.,section shows lesion arranged in nests and cords. individual tumor cell are round to oval with eosinophilic cytoplasm. nuclei are pleomorphic with inconspicuous nucleoli. stroma showing fibrosis and lymphocytic infiltrate.,chest wall recurrence biopsy :suggestive of recurrent carcinomatic deposits in known and treated case of carcinoma right breast.
MR160003233,right breast mass malignant.,biopsy from right breast.,received 3 grey white to grey brown linear core measuring 0.5 to 1cm. entire tissue processed.,section from the linear cores shows breast parenchyma harboring tumor cells arranged in tubules small islands and sheets .cells have moderate cytoplasm with round to oval pleomorphic nuclei and prominent nucleoli. atypical mitotic figures are discerned.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160003253,known case of carcinoma left breast.,scar nodule excision biopsy(post mrm and ct left breast).,received skin covered fibrofatty tissue measures 3.8 x 1.5 x 1.4 cm. entire tissue processed.,section shows tumor cells in sheets nests and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,scar nodule excision biopsy(post mrm and ct left breast) :suggestive of recurrence of invasive ductal carcinoma.
MR160003311,right breast lump carcinoma.,breast from right breast lump.,received multiple grey white linear cores measuring 0.2 to .5cm. entire tissue is processed.,linear cores of tissue exhibiting a neoplastic lesion arranged in broad bands and islands consisting of ovoid cellswith moderate atypia eosinophilic cytoplasm and brisk mitotic activity.there are prominent areas of necrosis fibrosis and mixed inflammatory infiltrate.,biopsy from right breast lump : suggestive of ductal carcinoma in situ with suspicious foci of invasion.suggest repeat biopsy or excision of the lump for further confirmation.
MR160003362,left breast lump carcinoma.,biopsy from left breast.,received 4 grey white to grey brown linear core measuring 1 to 1.2cm. entire tissue processed.,section show linear cores of breast parenchyma harboring a lesion arranged in cords tubules. individual cells are pleomorphic with round to oval hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. stroma is fibrous with bland stromal cells and inflammatory infiltrate.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160003403,right breast lump carcinoma.,biopsy from right breast.,received 4 grey white to grey brown linear core measuring 0.5 to 1cm.entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords tubules. individual cells have pleomorphic hyperchromatic round to oval nuclei and moderate amount of eosinophilic cytoplasm. stroma is fibrous with gland stromal cells.,invasive ductal carcinoma biopsy from right breast.modified br score is 5 9 grade 1tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9
MR160003518,left breast lump carcinoma.,biopsy from left breast.,received 4 grey white to grey brown linear core measuring 1 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged predominantly as cords and trabeculae and occasional tubules. the neoplastic cells exhibit nulcear hyperchromasia moderate nuclear pleomorphism and have moderate cytoplasm. the intervening stroma is desmoplastic.,invasive carcinoma biopsy from left breast. poorly differentiated ductal lobularmodified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 no ductal carcinoma in situ component noted.no lymphovascular emboli seen.
MR160003642,right breast mass carcinoma.,right breast mass biopsy.,received multiple grey white to grey brown linear cores measuring 1.2 to 1.3cm. entire tissue is processed.,section shows 4 cores of breast tissue harboring a lesion arranged in cords and nests with individual cells showing mild to moderate pleomorphism with round to oval hyperchromatic nuclei few with prominent nucleoli and moderate to scanty eosinophilic cytoplasm with irregular borders. stroma shows hyalinization.,right breast mass biopsy.invasive ductal carcinoma mbr score 6 9tubule formation 3 nuclear pleomorphism 2mitotic figures 1 6 9
MR160003660,carcinoma right breast(post nact).,right breast right modified radical mastectomy.,received in : formalin procedure : modified radical mastectomy laterality : right total dimensions : medial lateral 23cm superficial deep 4cm superior inferior 15cmskin ellipse : 15x9cm nipple and areola : unremarkable scar surgical defect : not seentumor : 1) relatively well circumscribed grey white fibrotic and calcified lesion measures 1.5x1x1cm located in inner quadrant. 2) tumor showing firm fibrotic areas located in inner upper quadrant. margins of tumor : 1) well circumscribed 2) illdefined deep margin : 1) 2.5cm 2) 1.5cmmuscle : absent adjacent breast : fibrofatty tissue axillary tail : 5x5x3cmtotal number of nodes : 18 lymph nodessize of largest node : 1x0.5x0.5cm,multiple sections from the breast parenchyma shows a residual tumor in nests and tubules. the tumor cells exhibit moderate nuclear pleomorphism vesicular nuclei and prominent nucleoli and eosinophilic cytoplasm. treatment related changes seen including foamy histiocytes lymphocytic infiltration calcification hyalinisation and elastosis seen.,right breast right modified radical mastectomy(post nact) :residual invasive ductal carcinoma grade 1.definite response to therapy is seen. modified bloom richardson score is 5(2+2+1). tumour is located in the upper inner quadrant. multiple tumor foci are identified largest measuring 0.5 cm in greatest dimension. lymphovascular invasion not identified. perineural invasion is not identified. ductal carcinoma in situ is not present. nipple and areola are unremarkable. posterior resection margin is free of tumor.lymph nodes : sixteen lymph nodes are identified negative for malignancy(0 16).summary:right mrm post nact residual invasive ductal carcinoma grade i.nodal metastases 0 16.
MR160003674,left breast carcinoma.,biopsy from left breast.,received 5 grey white linear cores measuring 1 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as tubules and islands and papillary pattern. the lining epithelial cells are cubiocolumnar have hyperchromatic nuclei moderate cytoplasm. foci of high grade ductal carcinoma in situ (solid and cribriform type) noted.,invasive carcinoma biopsy from left breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160003709,mass right breast carcinoma.,biopsy from right breast.,received 4 grey white linear cores measuring 0.7 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters tubules and islands is noted. the neoplastic cells have hyperchromatic to vesicular nuclei conspicuous nucleoli and moderate cytoplasm. areas of necrosis seen.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160003815,right breast mass carcinoma.,right breast mass trucut biopsy.,received multiple grey white to grey brown linear cores measuring 1 to 1.2cm.entire tissue is processed.,section shows cores of breast tissue harboring a lesion arranged in cords and nests.individual cells are markedly pleomorphic with atypical pleomorphic hyperchromatic nuclei few with prominent nucleoli .scanty to moderate amount of eosinophilic clear cytoplasm. stroma shows fibrosis and focal areas of necrosis.,right breast mass trucut biopsy.invasive ductal carcinoma.mbr score grade iitubule formation 2nuclear pleomorphism 3mitotic figures(activity) 2 7 9
MR160003816,left breast lump carcinoma.,biopsy from left breast.,received multiple grey white to grey brown linear cores measuring 1 to 1.2cm.entire tissue is processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged as tubules cords and nests. the cells have round to oval hyperchromatic pleomorphic nuclei few with prominent nucleoli and moderate cytoplasm. ductal carcinoma in situ with comedonecrosis present.,biopsy from left breast invasive ductal carcinoma grade ii.mbr score is 7 9tubule formation 2nuclear pleomorphism 3mitotic figures 2 7 9 ductal carcinoma in situ comedonecrosis present.
MR160003821,right breast lump carcinoma.,right breast core biopsy.,received multiple grey white to grey brown linear cores 1 to 1.2cm.entire tissue is processed.,section shows cores of breast parenchyma harboring a neoplastic lesion in cords and tubules.cells show moderate amount of eosinophilic cytoplasm pleomorphic hyperchromatic nuclei and prominent nucleoli.mitotic figures discerned.stroma shows mild inflammatory infiltrate.,right breast core biopsy : infiltrating ductal carcinoma.mbr score (6 9) grade iitubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR160003830,carcinoma breast with brain metastasis.,biopsy from left breast.,received 5 grey white to grey brown linear cores measuring 0.4 to 1.0cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords and trabeculae. the neoplastic cells have hyperchromatic nuclei and scant cytoplasm. crush artifact seen. foci of carcinoma in situ (lcis) noted.,invasive carcinoma biopsy from left breast. invasive lobular carcinoma.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160003847,left breast lump neoplastic.,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 0.4 to 1cm.entire tissue processed.,linear cores of breast parenchyma incorporating tumor arranged as islands and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is fibrous.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160003854,right breast lesion with ulceration carcinoma right breast.,biopsy from right breast.,received 4 grey white to grey brown linear cores measuring 1 to 1.2cm.entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a neoplastic lesion arranged as diffuse sheets cords. the cells have hyperchromatic pleomorphic nuclei with moderate cytoplasm. mitotic figures discerned. lymphovascular invasion identified.,invasive ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 lymphovascular emboli seen.
MR160003866,right breast mass carcinoma.,biopsy from right breast.,received 6 grey white to grey brown linear core measuring 1 to 1.3cm. entire tissue processed.,section shows linear cores of breast parenchyma with diffuse sheets of pleomorphic cells with hyperchromatic round to oval nucleus with prominent nucleoli moderate atypia and moderate to abundant cytoplasm.,invasive ductal carcinoma biopsy from right breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 areas of necrosis seen.
MR160003875,left breast lump carcinoma left breast.,biopsy from left breast lump.,received 5 grey white to grey brown linear cores measuring 1 to 1.5cm.entire tissue processed.,section show linear cores of breast parenchyma harboring a neoplastic lesion arranged as diffuse sheets of pleomorphic cells with hyperchromatic round to oval nuclei with moderate atypia and moderate cytoplasm. few cells show prominent nucleoli and vacuolated cytoplasm.,biopsy from left breast lump :invasive ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160003895,left breast lump phyllodes carcinoma.,biopsy from left breast lump.,received 4 grey white to grey brown linear core measuring 0.9 to 1.2cm. entire tissue processed.,section show linear cores of breast parenchyma harboring a neoplastic lesion arranged as diffuse sheets. the cells are pleomorphic with hyperchromatic nuclei and moderate atypia and moderate cytoplasm. atypical mitotic figures discerned.,invasive ductal carcinoma biopsy from left breast lumpmodified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 areas of necrosis seen.
MR160003902,irregular lesion left breast with multiple fibroadenoma carcinoma breast (2 0 clock position).,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 1 to 1.1cm.entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by sheets cords and nests of pleomorphic cells with round to oval hyperchromatic nuclei and moderate atypia. atypical mitotic figures discerned.,invasive ductal carcinoma biopsy from left breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160003957,muo left neck.,left cervical lymph node biopsy (level v),received single lymph node measuring 2x1.7x1cm.cut surface is unremarkable.,section reveals lymph node infiltrated by cellular sheets of round to ovoid neoplastic cells with vesicular nuclei prominent nucleoli and abundant eosinophilic cytoplasm.mitotic figures are discerned.there are interspersed vascular channels and aggregates of lymphocytes.,left cervical lymph node biopsy (level v) :metastatic carcinoma adenocarcinoma please look for primary in lung breast git.suggest ihc.
MR160003964,mass in right breast carcinoma breast.,biopsy from right breast.,received 3 grey white to grey brown linear cores measuring 0.7 to 1cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters and tubules and cords. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.probable lymphovascular emboli seen.,invasive ductal carcinoma biopsy from right breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160003994,carcinoma right breast.,a) sentinel nodes.b) wide local excisionc) axillary lymph nodes.,a) received fibrofatty tissue measuring 4.5x2.5x1cm largest lymph node measuring 1.8x1x0.8cm.cut surface shows fatty infiltration.dissected one node.b) received lumpectomy specimen measuring 6.5x5.5x4cm skin ellipse measuring 4.5x0.7cm.cut surface shows grey white lesion measuring 3.2x2.0x1.7cm.superior margin 1.2cminferior margin 1cmmedial margin 3cmlateral margin 2cmdeep margin 0.8cmc) received single fibrofatty tissue measuring 7x5x3cm.largest lymph node measuring 2x1x1cm cut surface shows fatty infiltration.total 13 lymph nodes isolated.,a) sentinel nodes: one node no metastatic deposits of tumor(0 1).b) wide local excision :tumor bed: the section from the tumor shows clumps groups of pleomorphic cells with pleomorphic vesicular nucleus with scanty cytoplasm.invasive ductal carcinoma.grade tubular formation 10 : 3nuclear pleomorphism : 3mitotic figures 12 10 : 2 8 9 nuclear grade ii lymphovascular invasion is present.perineural invasion is present.ductal carcinoma insitu is not seen.resected margins : superior margin free of tumor.inferior margin free of tumor.medial margin free of tumor.lateral margin free of tumor.deep margin free of tumor.c) axillary lymph nodes :one lymph node show metastatic deposits of tumor out of 13 nodes(1 13)perinodal spread is present.,a) sentinel nodes: one node no deposits of tumor.b) wide local excision :invasive ductal carcinoma.nuclear grade iiilymphovascular invasion is present.perineural invasion is present.ductal carcinoma insitu is not seen.all resected margins are free of tumor.c) axillary lymph nodes :one node shows metastatic deposits of tumor out of 13nodes(1 13).
MR160003995,carcinoma breast post op,biopsy from right pleural nodule,received multiple grey white to grey brown linear cores measures 0.8 1cm. entire tissue processed.,section shows linear cores harboring a lesion arranged in nests cords and vague glandular pattern. the individual neoplastic cells show increase n c ratio mildly pleomorphic hyperchromatic nuclei with inconspicuous nucleoli and scant to moderate amount of pale eosinophilic cytoplasm mitotic activity is discerned (2 3 hpf) . intervening stroma is composed of fibrocollagenous connective tissue. extensive necrosis seen.,biopsy from right pleural nodule:poorly differentiated carcinoma metastatic from breast.suggest ihc.
MR160004024,mass in right breast carcinoma breast.,biopsy from right breast.,received 4 grey white to grey brown linear cores altogether measuring 0.4x0.4x0.2cm.entire tissue processed.,linear cores of breast parenchyma showing areas of necrosis and inflammatory cell infiltrate with predominance of lymphocytes plasma cells and histiocytes. a few multinucleated giant cells are seen. cholesterol clefts and haemosiderin laden macrophages seen.,necrotising granulomatous inflammation biopsy from right breast.no evidence of malignancy in the cores submitted.kindly correlate with clinical and imageological findings and suggest repeat biopsy if deemed necessary.
MR160004032,carcinoma right breast post lumpectomy post nact.,right breast right modified radical mastectomy(post lumpectomy and post nact).,received in : formalinprocedure : modified radical mastectomy.laterality : right total dimensions : medial to lateral 16cm. superficial to deep 15cm. superior to inferior 6.5cm.skin ellipse : 11 x 7cm. nipple :normal unremarkable. scar : seen above nipple areola measuring 4 cm.tumour size : no obvious tumor is seen. adjacent breast : fibrofatty. axillary tail :7 x 4 x 2 cm.size of largest node : 1.5 x 1 x 0.5 cm cut surface grey brown.representative sections are submitted.,section shows small focus of ductal carcinoma in situ along with ducts showing adenosis fibrocystic change and apocrine change. treatment related changes are seen. no evidence of invasive carcinoma is seen.,right breast right modified radical mastectomy (post lumpectomy and post nact) :shows focus of ductal carcinoma in situ of cribriform and comedo pattern with intermediate nuclear grade. size of the ductal carcinoma in situ measures 0.6 cm in greatest dimension. no evidence of invasive carcinoma is seen. treatment related changes are seen. lymphovascular or perineural invasion is not identified. nipple and areola are free of tumor. posterior resection margin is free of tumor.lymph nodes:nineteen lymph nodes are identified negative for malignancy (0 19).pathological stage : yptis(dcis) n0
MR160004041,known case of sarcomatoid carcinoma of left breast.complaining of right breast lesions.,biopsy from right breast lesion.,received multiple grey white linear core measuring 1 to 1.2cm.entire tissue is processed.,linear cores of breast parenchyma exhibiting a neoplastic lesion arranged in nests islands cords consisting of ovoid to round cells demonstrating moderate atypia and eosinophilic cytoplasm.mitotic figures are discerned.intervening areas show desmoplasic stroma and myxoid change.,biopsy from right breast lesion :invasive carcinoma grade iimbr score is 6 9tubular formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR160004089,lump from left breast.,a) left breast lumpectomy.b) lump in retroareolar region.c) left modified radical mastectomy.,a)fresh tissue received : yesnumber of specimens received : 1 laterality : left procedure : lumpectomyspecimen orientation : not orientated specimen size : 4.5x3.5x3.3cm skin : present skin dimensions : 2.5x.0.5cm skin abnormalities : absent nipple : absent lesion(s) : presentnumber of macroscopically visible lesions : 1 lesion dimensions : 1.4x1.3x1.5cmdistance of lesion to nearest margin 0.2cmb) received single soft tissue bits measuring 2x1.5x0.8cm.cut surface show grey white lesion 1.8x1.5x0.7cm.distance from closest ink margin is 0.1cm.c)received in : formalinprocedure : mastectomy laterality : lefttotal dimensions : medial lateral 17cm superficial deep 15cm superior inferior 4.5cmskin ellipse : 14x10.5cm.nipple :normal scar surgical defect : located 4cm above in upper inner quadrant and medial to not applicable.tumour size : lumpectomy cavity measuring 5.5x4.5x4cm grey white areas about 1cm. location of tumor : upper inner quadrant. margins of tumor : deep margin of lumpectomy defect : 1cm muscle : absent adjacent breast : fibrofatty axillary tail : 7x6x3cm.size of largest node : 2.2x1.8x1.5cm.,a) amp b) sections show breast parenchyma harboring a lesion arranged in nests and sheets.the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few.atypical mitotic figures are discerned.stroma shows desmoplasia with inflammatory infiltrates.,a) left breast lumpectomy:invasive ductal carcinoma grade iimbr score (2+2+2 6 9) tumor measures 1.5cm in greatest dimension. skin is free of tumor.b) lump in retroareolar region :invasive ductal carcinoma.grade ii.(mbr score 2+2+2)ductal cacinoma insitu solid and with comedonecrosis seen.tumor measures 1.8cm in greatest dimension.c) left modified radical mastectomy :residual invasive ductal carcinoma grade ii.residual tumor measures 1.0cm in greatest dimension.tumor is located in upper inner quadrant.lymphovascular invasion is not identified.perineural invasion is not identified.posterior margin of resection is free of tumor.nipple and areola is free of tumor.ductal carcinoma in situ cribriform pattern is seen.isolated one out of twenty lymph nodes show tumor deposits(1 20).no perinodal spread is noted.
MR160004112,right breast mass carcinoma.,biopsy from right breast mass.,received 4 greywhite linear cores measuring 0.8 to 1cm.,linear cores of breast parenchyma infiltrated by neoplasm arranged as cords and trabeculae.the neoplastic cells are hyperchromatin and have moderate cytoplasm.the intervening stroma is desmoplastic.,invasive carcinoma with lobular features biopsy from right breast.mbr score is 6 9 grade 2tubule formation:3nuclear pleomorphism:2mitotic figures:1
MR160004115,carcinoma right thyroid.,a) hemithyroidectomy with tracheal resection.b) left hemithyroidectomy.,a) received lobe of thyroid with adherent tracheal ring measuring 5.5x3.2x3cm.lobe of thyroid measuring 4x3.2x3cm attached muscle measuring 3x1.5x0.7cm.tracheal ring measuring 2x2x1.5cm.cut surface of specimen shows ill defined greywhite tumor with areas of hemorrhage with gritty sensation measuring 3.5x3.3x3cm tumor breaching trachea isthmus is unremarkable.tumor is reaching upto the inked margins.also received in same container tracheal ring measuring 2x1.2x0.3cm.b) received lobe of thyroid measuring 2.7x2x0.8cm.cut surface is unremarkable.,a) section shows thyroid incorporating a neoplasm arranged as nodules composed by microfollicles which are separated by thick fibrous septae.angiolymphatic invasion seen.extrathyroidal extension noted.tumor infiltrates trachea and reaches the inked margin.section from adjacent muscle is unremarkable.section from separately submitted semicircular ring of trachea is free of tumor.b) sections from left lobe of thyroid shows nodules of colloid filled follicles of varying sizes lined by flattened to cuboidal epithelium.,a) papillary carcinoma thyroid follicular variant right breast.tumor size: 3.5x3.3x3cm.angiolymphatic invasion seen.extrathyroidal extension noted.tumor infiltrates trachea.adjacent muscle is free of tumor.separately received semicircular tracheal ring segment is free of tumor.b) left lobe of thyroid: free of tumor.
MR160004119,right breast lump malignant.,biopsy right breast.,received multiple grey white to grey brown linear cores measuring 1 to 1.2cm.entire tissue is processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters and tubules.probable lymphovascular emboli seen.the intervening stroma is desmoplastic.,infiltrating ductal carcinoma biopsy right breast grade i.mbr score is 5 9tubular formation 2 nuclear pleomorphism 2 mitotic figures 1 5 9
MR160004142,mass in right breast carcinoma breast.,right breast core biopsy.,received 3 grey white to grey brown linear cores measuring 1 to 1.2cm.entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR160004158,mass in right breast carcinoma.,biopsy from right breast.,received 4 grey white to grey brown linear cores measuring 1 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma harboring cellular lesion arranged as nests and sheets. the cells have irregular hyperchromatic nuclei conspicuous nucleolus and moderate amount of cytoplasm. mitotic figures are discerned .lymphoplasmacytic infiltrate noted.,invasive ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 foci suggestive of high grade comedoductal carcinoma in situ noted.
MR160004186,left breast lump carcinoma.,trucut biopsy of left breast lump.,received multiple grey white to grey brown linear cores measuring 0.7 to 1cm.,section shows cores of breast parenchyma with an infiltrative lesion arranged in tubules cords and nests separated by fibrous septae.cells display round to oval vesicular nuclei few with prominent nucleoli and moderate amount of eosinophilic cytoplasm.mitotic figures are discerned.myxoid background is noted.ductal carcinoma in situ seen.stroma shows mild lymphocytic infiltration and hemorrhage.,invasive ductal carcinoma grade ii.mbr score is 6 9.tubular formation 2nuclear pleomorphism 2mitotic figures 2 6 9 foci of ductal carcinoma insitu noted.lymphovascular invasion not seen.perineural invasion not seen.
MR160004191,mass in right breast carcinoma breast.,right breast mass core biopsy.,received 4 grey white linear cores measuring 1 to 1.3cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in nests cords and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast mass core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR160004215,left breast lump carcinoma.,biopsy left breast.,received multiple grey white linear cores measuring 1 to 1.2cm.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters and tubules.the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm.the intervening stroma is desmoplastic.,infiltrating ductal carcinoma biopsy left breast grade ii.mbr score is 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR160004255,carcinoma right breast.,a) sentinel lymph nodes.b) wide local excision.c) revised superior and inferior margind) axillary dissection.,a) received fibrofatty tissue measuring 3x3x1cm.sentinel lymph node measuring 0.8x0.7x0.6cm cut surface shows grey white.one node present measuring 0.8x0.7x0.6cm.b) received lumpectomy specimen measuring 6.5x4.5x3.3cm.skin ellipse measuring 3.5x1cm on serial section.tumor measuring 2.2x1.8x1.8cm.superior margin 1.2cmmedial margin 1.2cminferior margin 1cmlateral margin 2.5cmdeep margin 0.3cmc) received single fibrofatty tissue measuring 6x3x1.5cm.one surface is noted.d) received fibrofatty tissue measuring 7x5x3.5cm.largest lymph node measuring 2x1x1cm.cut surface shows fatty infiltrate.total 18 lymph nodes isolated.,a) sentinel lymph nodes :one node no metastatic deposits of tumor.b) wide local excision :tumor bed tumor consists of pleomorphic polygonal cells with hyperchromatic nucleus and eosinophilic cytoplasm.invasive ductal carcinoma.grade: tubular formation 30 : 2nuclear pleomorphism 6 10 : 2mitotic figures : 2 mbr score 6 9 nuclear grade iiductal carcinoma insitu is not present.lymphovascular invasion is not present.perineural invasion is not present.resected margins: superior margin free of tumor.medial margin free of tumor.inferior margin free of tumor.lateral margin free of tumor.deep margin show 0.3cm free of tumor.c) revised superior and inferior margin:shows fibrofatty tissue free of tumor.d) axillary dissection:10 nodes show no deposits of tumor.,tumor bed: invasive ductal carcinoma. nuclear grade ii. maximum dimension of tumor 2.2x1.8x1.8cm. lymphovascular invasion is not present. perineural invasion is not present. ductal carcinoma insitu is not present. all resected margins are free of tumor.sentinel lymph nodes : one node no metastatic deposits of tumor out of 1 node.axillary nodes 10nodes no metastatic deposits of tumor.
MR160004256,left breast lump carcinoma.,biopsy from left breast lump.,received 4 grey white to grey brown linear cores measuring 0.6 to 1.5cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplastic lesion arranged as clusters nests and occasional tubules. the neoplastic cells exhibit moderate nuclear pleomorphism vesicular nuclei with moderate amount of cytoplasm. intervening stroma shows desmoplastic response composed of lymphocytes and fibroblasts.,biopsy from left breast lump:infiltrating ductal carcinoma.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160004288,case of right carcinoma breast.,a) right breast lumpectomy.b) axillary lymph node dissection.,a) received lumpectomy specimen measures 9.5x9x3cm. on cut surface shows fibrotic necrotic area measures 2x1x0.9cm. located at the following distances from the respective margins : superior margin 1cminferior margin 2.5cmmedial margin 1cmlateral margin 2cmb) received fibrofatty tissue measures 7x5x3cm. largest lymph node measures 0.9x0.5x0.4cm. cut surface shows grey brown appearance. total 12 lymph nodes identified.,a) right breast lumpectomy:tumor shows fibrotic necrotic collection of inflammation cells with foreign body giant cells. there is no evidence of residual viable tumor present.resected margin superior margin free of tumorinferior margin free of tumormedial margin free of tumorlateral margin free of tumorb) axillary lymph node dissection:12 nodes no deposits of tumor.,a) right breast lumpectomy:breast lumpectomy post lumpectomy and post nact.no residual viable tumorfibroti necrotic and granulation tissue.all resected margins are free of tumorb) axillary lymph node dissection:12 nodes no deposits of tumor.
MR160004326,right breast lump carcinoma.,biopsy from right breast.,received 3 grey white linear cores measuring 0.7 to 1cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma shows chronic inflammatory cell infiltrate.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160004339,mass in right breast carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measuring 0.8 to 1cm.entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as islands and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is scant.,invasive carcinoma biopsy from right breast.modified br score is 8 9 grade 3tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR160004344,complaint of lump right breast.,a) sentinel nodes.b) lump right breast.c) axillary lymph nodes.,a) received fibrofatty tissue measuring 4x3.5x1.5cm.two nodes dissected each measuring 1.5x1cm.b) received lumpectomy specimen with skin ellipse 4.5x4x3cm.skin ellipse measuring 2.5x0.8cm.on serially slicing found a grey white tumor measuring 2.8x1.5x1.2cmsuperior margin 1.3cminferior margin 1.8cm.medial margin 1cmlateral margin 1cmdeep margin 1.8cm.c) received fibrofatty tissue measuring 7x5x2cm.largest lymph node measuring 2x1.2x1cm.cut surface shows fatty infiltration.isolated 11 nodes.,a) sentinel nodes (frozen specimen) : two nodes no metastatic deposits of tumor.b) lump right breast:tumor bed: composed of pleomorphic oval to residual cells with hyperchromatic nucleus and scanty cytoplasm. invasive ductal carcinoma.grade tubule formation 30 : 2nuclear pleomorphism 8 10 : 2mitotic figures : 2 mbr score is 6 9 nuclear grade ii.ductal carcinoma in situ is present.lymphovascular invasion is not presentperineural invasion is present.all resected margins are free of tumor.c) axillary lymph nodes :11 nodes show no deposits of tumor.,lumpectomy wide local excision.invasive ductal carcinoma.maximum dimension of tumor 2.8x1.5cm.nuclear grade ii.ductal carcinoma insitu is present with camedonecrosis.lymphovascular invasion is not present with comedonecrosis.perineural invasion is present.all resected margins are free of tumor.lymph nodes: 11 nodes show no deposits of tumor.
MR160004354,left breast mass lesion carcinoma.,left breast mass biopsy.,received 3 grey white to grey brown linear cores measuring 0.5 to 1cm.entire tissue processed.,section shows linear cores of breast parenchyma harboring a small focus of lesion arranged in sheets containing ovoid cells having moderate amount of cytoplasm and hyperchromatic nucleus. stroma shows extensive areas of sclerosis with inflammatory infiltrates. areas of hemorrhage and necrosis is seen.,left breast mass biopsy :small focus of invasive ductal carcinoma nuclear grade 2.please correlate clinically.
MR160004425,known case of carcinoma left breast.right breast lump suspicious for malignancy.,biopsy from right breast.,received multiple grey white to grey yellow linear cores measures 1 to 1.5cm. entire tissue processed.,linear cores of fibrous and hemorrhagic tissue harboring a few ducts with hyperchromatic nuclei. the lumen of ducts is filled by small to medium uniform polygonal cells.,biopsy from right breast:small focus of intermediate grade ductal carcinoma in situ.no focus of invasion seen in the cores submitted.
MR160004448,right breast lump carcinoma.,biopsy from right breast.,received 5 grey white linear core measuring 0.5 to 0.8cm. entire tissue processed.,linear cores of neoplastic tissue composed of tumor arranged as sheets and islands. the neoplastic cells are polygonal have hyperchromatic nuclei and moderate cytoplasm large areas of necrosis seen.,invasive carcinoma biopsy from right breast.modified br score is 8 9 grade 3tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR160004500,left breast lump carcinoma.,biopsy from left breast.,received 3 grey white linear cores measuring 0.8 to 1cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters and islands. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. lymphovascular emboli seen. the intervening stroma is desmoplastic.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160004553,lump in left breast.,biopsy from left breast.,received 3 grey white linear cores measuring 1 to 1.3cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by neoplasm arranged in cords and occasional tubules. the neoplastic cells have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,invasive carcinoma with lobular features biopsy from left breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160004559,carcinoma breast few lesions in segment vii viii of liver.,biopsy from liver.,received multiple grey white to grey brown linear cores measuring 0.8 1.2cm. entire tissue processed.,section shows linear cores of liver parenchyma harboring a lesion arranged in small nests cords and clusters cells exhibit nuclear pleomorphism hyperchromasia and scanty cytoplasm. areas of fibrosis seen.,biopsy from liver:metastatic carcinoma in a known case of carcinoma breast.
MR160004615,right breast lump carcinoma.,trucut biopsy of right breast lump.,received 5 greywhite to greybrown linear cores measuring 1 to 1.2cm.,linear cores of breast parenchyma harboring cellular lesion arranged as nests.the cells have hyperchromatic nucleus inconspicuous nucleoli and moderate amount of cytoplasm.mitotic figures are discerned. the intervening stroma is desmoplastic.,invasive ductal carcinoma grade ii.tubule formation :2nuclear pleomorphism:2mitotic figures :3 mbr score is 7 9
MR160004643,large left breast lump carcinoma.,biopsy from left breast lump,received 4 grey white to grey brown linear core measuring 0.9 to 1cm. entire tissue processed.,smear show linear cores of breast parenchyma harboring a lesion arranged in tubules nests and sheets. the cells are ovoid having moderate amount of cytoplasm and hyperchromatic nucleus. atypical mitotic figures are discerned. areas of hemorrhage and necrosis seen. stroma shows desmoplasia with inflammatory infiltrates.,invasive ductal carcinoma biopsy from left breast lump modified br score is 7 9 grade 2tubule formation : 2nuclear pleomorphism : 2mitotic figures : 3 7 9
MR160004668,carcinoma left breast post op post chemo post rt.,bilateral oophorectomy.,received bilateral oophorectomy specimensmaller one : ovary measures 3x2.5x1.2cm. fallopian tube measures 4cm in length.attached fimbrial end identified paratubal cyst seen.cut surface shows corpus hemorrhagica seen measures 1x1cm. rest of the ovary is unremarkable.larger one : received a collapsed already cut opened cystic mass with attached fallopian tube and fimbrial end. cystic mass measures 10x7x2cm. fallopian tube measures 3.5cm cut surface shows multiloculated cyst inner wallis smooth with no solid area or papillary projections no normal ovarian tissue not seen.,one side ovary: multiple section show corpus luteal cyst and hemorrhagic cyst with ovarian stroma shows spindle cells with thickened blood vessels. no evidence of malignancy. fimbrial cyst is present lined with flattened epithelium with normal tube.other side ovary: multiple sections show cystic spaces lined with flattened cuboidal epithelium with fibrocollagenouswall. at one end fimbrial cyst is present. no evidence of malignancy.,one side ovary: corpus luteal cyst and hemorrhagic cyst.other side ovary: benign cyst.
MR160004671,carcinoma right breast.,right modified radical mastectomy.,received in : formalin fixed.procedure : mastectomy.laterality : right. total dimensions : medial lateral: 23cm. superficial deep:4.5cm. superior inferior:16cm. skin ellipse : 12.5x6.5cm. nipple : normal.scar surgical defect : not seen.tumour size : 2.3x1.5x1.5cm. location of tumor : upper outer. margins of tumor : ill defined. deep margin : 1.5cm.muscle : present 3x1.8cm.adjacent breast : fibrofatty tissue. axillary tail : 7x6x2.5cm.total number of nodes : 13 size of largest node : 2x1.5x0.8cm.cut surface:tumor deposit.,multiple sections from breast parenchyma show a neoplastic lesion arranged in tubules cords and diffuse sheets.tumor cells are pleomorphic with vesicular nuclei prominent nucleoli and moderate cytoplasm.multinucleated tumor giant cells seen.mitotic figures discerned.areas of myxoid change noted.stroma shows desmoplasia.lymphovascular and perineural invasions are noted.,right breast right modified radical mastectomy: invasive dutcal carcinoma grade ii.modified br score is 7 9.tubule formation: 2nuclear pleomorphism: 3mitotic figures: 2tumor measures 2.3cm in greatest dimension and is located in the upper outer quadrant. ductal carcinoma in situ is not seen.lymphovascular invasion is identified.perineural invasion is identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: 13 lymph nodes metastasis: 3(3 13) . largest deposit measuring 1.1cm in greatest dimension.perinodal spread not seen.summary : right mrm invasive ductal carcinoma grade ii. nodal metastases present(3 13). resected margins are free of tumor
MR160004687,carcinoma right breast.,biopsy from right breast.,received 4 greywhite to greybrown soft tissue bits measuring 2x1x0.3cm. entire tissue processed.,section shows multiple fragments few are lined by denuded necrotic epithelium and few by squamous epithelium harboring cellular lesion arranged as nests and sheets. the cells have vesicular nucleus prominent eosinophilic nucleoli and moderate amount of cytoplasm. mitotic figures are discerned. dermal infiltrates are seen. epidermis is free of tumor.,invasive ductal carcinoma grade iii.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 dermal infiltrates are seen.
MR160004703,mass in right breast carcinoma breast.,biopsy from right breast mass.,received multiple greywhite linear cores measuring 1 to 1.2cm.entire tissue is processed.,section shows linear cores of breast parenchyma harboring cellular lesion arranged as nests and tubules.the cells exhibit moderate degree of nuclear pleomorphism.mitotic figures are discerned.,invasive ductal carcinoma grade ii.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 mbr score 6 9
MR160004757,mass in left breast carcinoma breast.,left breast core biopsy.,received 3 grey white to grey brown linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in sheets and tubules. individual cells are pleomorphic with round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows bland stromal cells. lymphovascular emboli seen.,left breast core biopsy.invasive ductal carcinoma grade ii.modified br score is 6 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160004768,left breast lump carcinoma.,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 1.2 to 1.4cm. entire tissue processed.,linear cores of cellular lesion arranged as nests cords and sheets. the cells have irregular hyperchromatic nucleus inconspicuous nucleoli and moderate amount of cytoplasm. few cells have clear cytoplasm. areas of calcification noted. mitotic figures are discerned.,invasive ductal carcinoma biopsy from left breast.modified br score is 6 9 grade 2tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 foci of calcification seen.
MR160004795,mass in right breast phyllodes carcinoma breast.,biopsy from right breast.,received 4 grey white to grey brown linear core measuring 0.9 to 1cm. entire tissue processed.,section shows linear cores of cellular lesion arranged as nests and sheets. the cells have vesicular to hyperchromatic nuclei few showing prominent nucleous and moderate amount of cytoplasm. nuclear pleomorphism is noted. mitotic figures are discerned. areas of necrosis identified.,invasive carcinoma biopsy from right breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160004860,history of excision of left axillary mass.metastatic squamous cell carcinoma.,a) left breast lump wide local excision.b) left axillary lymph node dissection.,a) received lumpectomy specimen measuring 6x4.8x1.8cm. skin ellipse absent.cut surface shows grey white lesion measuring 1.5x1x0.3cm.located at the following distances from the respective margins superior margin 1cminferior margin 2cmmedial margin 2cmlateral margin 1.5cmb) received skin covered fibrofatty tissue measuring 9x5x2cm.skin ellipse measuring 6x1.2cm.largest lymph node measuring 3x2x1cm with necrotic and fibrotic areas. isolated 13 nodes.,a) left breast lump wide local excision :tumor bed: the section shows clumps groups of pleomorphic cells with hyperchromatic nucleus and eosinophilic cytoplasm.invasive ductal carcinoma.grade tubule formation lt 10 3nuclear pleomorphism 8 10 2 mitotic figures 3 8 9 nuclear grade iii.ductal carcinoma in situ is not present.lymphovascular invasion is indeterminate.perineural invasion is present.resected margins superior margin free of tumor.inferior margin free of tumor.medial margin free of tumor.lateral margin free of tumor.deep margin free of tumor.b) left axillary lymph node dissection :13 nodes show no metastatic deposits of tumor.one mass shows fibrotic area with inflammatory cellular infiltration with giant cells.surface epithelium show hyperplasia and epithelium dysplasia no malignancy.,a) left breast lump wide local excision :invasive ductal carcinoma.nuclear grade iii.maximum dimension of tumor is 1.5x1x0.8cm.ductal carcinoma in situ is not present.lymphovascular invasion is indeterminate.all resected margins are free of tumor.b) left axillary lymph node dissection :13 nodes no deposits of tumor seen. one mass show below the skin shows fibrosis necrosis inflammatory cells and giant cells.
MR160004866,right breast lump carcinoma.,biopsy from right breast.,received 5 grey white to grey brown linear cores measuring 0.9 to 1.3cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm.the intervening stroma is fibrous.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 lymphovascular emboli seen.
MR160004901,mass in left breast carcinoma breast.,biopsy from left breast.,received 3 grey white to grey brown linear core measuring 1 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma harboring cellular lesion arranged as nests and sheets. the cells have vesicular to hyperchromatic nucleus conspicuous nucleoli and moderate amount of cytoplasm. mitotic figures are discerned. areas of necrosis identified.,invasive ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 6 9 foci of necrosis seen.
MR160004902,right breast lump carcinoma.,biopsy from right breast.,received 5 grey white to grey brown liner core measuring 0.9 to 1.2cm.entire tissue processed.,linear cores of breast parenchyma infiltrates by a neoplasm arranged as clusters and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is fibrous.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 lymphovascular emboli seen.
MR160004972,right breast lump carcinoma.,biopsy from right breast lump.,received 4 grey white to grey brown linear cores measuring 0.9 to 1cm. entire tissue processed.,section shows cores of breast parenchyma harboring a lesion arranged in nests cords and trabeculae. individual cells are large with pleomorphic hyperchromatic nuclei with irregular border and inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. intranuclear inclusion are noted. brisk mitotic activity noted. stroma shows desmoplasia. areas of necrosis seen.,invasive ductal carcinoma biopsy from right breast lump.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160005010,mass in left breast carcinoma breast.,left breast mass core biopsy.,received 3 grey white to grey brown linear cores measuring 1 to 1.5cm.entire tissue processed.,section shows breast parnchyma harboring a lesion with cells arranged in nests tubules and trabeculae cells have moderate amount of clear to eosinophilic cytoplasm with centrally placed hyperchromatic nuclei .extracellular mucin pool is noted. stroma shows desmoplasia.,left breast mass core biopsy :invasive ductal carcinoma with focal mucinous areas.modified br score is 6 9 grade ii.tubule formation : 3nuclear pleomorphism : 2mitotic figures :1 6 9
MR160005057,right breast lump carcinoma.,biopsy from right breast.,received 3 grey white to grey brown linear core measuring 1.2 to 1.4cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as tubules clusters and cords. the neoplastic cells exhibit moderate nuclear pleomorpism hyperchromasia and have moderate cytoplasm. lymphovascular emboli seen.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 lymphovascular emboli seen.
MR160005303,left breast lump carcinoma,left breast lump core biopsy.,received 5 grey white to grey brown linear core measuring 0.6 to 1cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells is nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 3 modified bloom richardson score 8(3+3+2).
MR160005314,carcinoma right breast.,a) right breast conservative surgery wide local excision.b) lymph nodes.,a) received lumpectomy specimen measuring 7x5.5x3cm.cut surface shows grey white lesion measuring 3x2.8x1cmlocated at the following distances from the respective margins : superior margin 1cminferior margin 3cmmedial margin 0.8cmlateral margin 0.6cmb) received fibrofatty tissue measuring 9x5x1cm.largest lymph nodes measuring 1x0.8x0.6cm.cut surface shows grey white.15 lymph nodes isolated.,tumor bed: shows clumps and groups of pleomorphic cells with hyperchromatic nucleus and scanty cytoplasm.invasive ductal carcinoma.grade : tubule formation 2nuclear pleomorphism 2mitotic figures 2 mbr score 6 9 ductal carcinoma insitu is not present.lymphovascular invasion is not present.perineural invasion is not present.resected margins : superior margin free of tumor.inferior margin free of tumor.medial margin free of tumor.lateral margin free of tumor.deep margin free of tumor.lymph nodes:15 nodes no deposits of tumor.,a) right breast conservative surgery wide local excision :invasive ductal carcinoma.maximum dimension of tumor is 3x2.8cm.nuclear grade iiductal carcinoma insitu is not present.lymphovascular invasion is not present.all resected margins are free of tumor.b) lymph nodes : 15 nodes no deposits of tumor(0 15)pathological stage : pt2n0.
MR160005361,left breast lump carcinoma.,biopsy from left breast.,received 3 grey white to grey brown linear cores each measuring 0.8 to 1cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as islands nests clusters. the neoplastic cells exhibiting moderate nuclear pleomorphism have vesicular nuclei and conspicuous nucleoli and moderate cytoplasm. lymphovascular emboli seen. the intervening stroma is desmoplastic.,infiltrating ductal carcinoma biopsy from left breast.modified br score is7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160005375,complaint of left carcinoma breast.,a) left breast lumpectomy.b) left mrm.,a) received unoriented lumpectomy specimen measuring 6x5x3cm.cut surface shows grey white areas measuring 2.2x1.8x1.5cm.another mass present measuring 1x0.8x0.5cm situated 1.5cm from tumor and 0.8cm from inked margin.closest margin measuring 0.3cm.two tumor masses present mesenteric.b) received in : formalinprocedure : mastectomy mrm laterality : left total dimensions : medial to lateral 18cm superficial to deep 17cm superior to inferior 7cmskin ellipse : 13x11.5cm nipple :normal scar surgical defect : present single measuring 6x0.5cm.tumor : lumpectomy bed no tumor seenlumpectomy bed : 7x7x4.5cm location of lumpectomy bed : upper inner quadrant deep margin : 0.6cm from lumpectomy bedmuscle : absent adjacent breast : fibrofatty axillary tail : 11x8cmsize of largest node : 3.5x2x1.5cm cut surface shows grey white appearance.,a) left breast lumpectomy :tumor bed shows two tumor masses are present.one tumor is measuring 2.2x1.8x1.5cm.another tumor mass is present measuring 1x0.8x0.5cm.the distance between the two is 1.5cm.two tumors show clumps groups and sheets of pleomorphic polygonal cells with hyperchromatic nucleus and scanty cytoplasm.two tumors with invasive ductal carcinoma.grade tubule formation lt 10 3nuclear pleomorphism 2mitotic figures 3 mbr score 8 9 nuclear grade iii.ductal carcinoma in situ is not present.lymphovascular invasion is present.perineural invasion is present.b) left breast left modified radical mastectomy: tumor bed: shows surrounding the lumpectomy area few ducts are showing epithelial hyperplasia and atypical hyperplasia.there is no evidence of residual tumor.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: 4 nodes show metastatic deposits out of 16nodes.(4 16) perinodal spread is present.,a) left breast lumpectomy :two tumors present one tumor measures 2.2cm second tumor measures 1x0.8cm.the distance between the tumor is 1.5cm.invasive ductal carcinoma nuclear grade iii.ductal carcinoma in situ is not present.lymphovascular invasion is present.perineural invasion is present.b) left breast left modified radical mastectomy: lumpectomy bed: no residual tumor is present.underlying resected margin are free of tumor.nipple and areola is unremarkable.lymph nodes: 4 nodes show metastatic deposits of tumor out of 16nodes.summary:left post lumpectomy mrm no residual tumor present.nodal metastases 4 nodes show metastatic deposits of tumor out of 16 nodes(4 16).
MR160005440,left breast lump carcinoma.,biopsy from left breast.,received multiple tiny linear fragments altogether measuring 0.4x0.3x0.2cm. entire tissue is processed.,linear cores of a neoplasm arranged as islands and sheets. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. areas of necrosis seen.,invasive ductal carcinoma biopsy from left breast.modified br score is 8 9 grade 3 tubule formation :3 nuclear pleomorphism :3mitotic figures :2 8 9
MR160005528,right breast lump carcinoma.,biopsy from right breast.,received 4 grey white to grey brown linear core measuring 1 to 1.4cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. intervening stroma is desmoplastic,infiltrating ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 lymphovascular emboli seen.
MR160005580,right breast lump carcinoma.,biopsy from right breast.,received 3 grey white to grey brown linear cores measuring 0.6 to 1.2cm.entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as cords and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism nuclear hyperchromasia and moderate cytoplasm. the intervening stroma is desmoplastic.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160005649,right breast lump.,a) wide local excision.b) right mrm.,a) received lumpectomy specimen measuring 5x4x3cm skin ellipse measuring 2x0.8cm. on serial sectioning 2 greywhite nodular lesion larger measures 2x1.5x1.3cm smaller measures 1.5x0.8x0.7cm.located at the following distances from respective margins: superior margin 1.3cminferior margin 1.5cmmedial margin 0.2cmlateral margin 0.8cmdeep margin 0.6cmb) received in : formalin.procedure : mr mastectomy.laterality : right. total dimensions : medial to lateral 20cm. superficial to deep 4.2cm. superior to inferior 17cm. skin ellipse : 11x7.5cm. nipple areola : unremarkable.scar surgical defect : 4cm in length located inferior to n a.lumpectomy bed : single.size : 6.5x6x4cm lumpectomy bed shows a small greywhite nodule measuring 0.7x0.6x0.5cm. distance to nearest separate tumor foci (when multiple ):location of lumpectomy bed: retroareolar. deep margin : distance of greywhite nodule from deep margin 0.5cm. muscle : absent.adjacent breast : fibrofatty tissue. axillary tail : 9x8x3cm.total number of nodes : 17lymph nodessize of largest node : 2x1.5x1cm cut surface:greywhite.,wide local excision breast lump:tumor bed:the section shows clumps groups of pleomorphic cells with hyperchromatic nucleus and eosinophilic cytoplasm.in focal areas mucin is present.invasive ductal carcinoma with focal mucinous areas present.tubular formation: (3)nuclear pleomorphism: (2)mitotic figures: 8 10 (2)mbr score is 7 9.nuclear grade : ii.lymphovascular invasion : not present.perineural invasion : not present.resected margin:superior margin free of tumor.inferior margin free of tumor.medial margin involved by tumor.lateral margin free of tumor.deep margin involved by tumor.,right breast post lumpectomy right modified radical mastectomy: tumor bed:small focus of residual tumor present measuring 0.7x0.6x0.5cm invasive ductal carcinoma with mucinous areas.modified br score is 7 9 grade ii.tubule formation: 3.nuclear pleomorphism: 2.mitotic figures: 2.tumor measures 0.7x0.6 cm in greatest dimension and is located in the retro areolar quadrant. ductal carcinoma in situ is not present.lymphovascular invasion is not present.perineural invasion is not present.posterior resection margin is free of tumor.nipple and areola is unremarkable.all other resected margins including medial margins are free of tumor.lymph nodes: 12 nodes show non caseating granulomas with epithelioid cells and langhan s giant cells.possibly tubercular lymph nodes kindly confirm.no deposits of tumor seen.summary:right mrm wide excsion with mastectomy invasive ductal carcinoma with mucinous areas grade ii.nodal metastases 12 nodes show granulomas with giant cells and epitheloid cells. poorly tubercular lymphadectomy confirm
MR160005669,carcinoma left breast (post lumpectomy and post chemo).,a) left breast left breast conservative surgery.b) left axillary lymph node dissection.,a) received lumpectomy specimen measuring 10.5 x 7.5 x 3.6 cm. skin ellipse measuring 9.5 x 1.5 cm shows a linear scar measuring 8 cm.on serial section there is seen a illdefined fibrocystic area measuring 5 x 2 x 1.8 cm.distance from margins :superior : 1.8cm.inferior : 0.5cm.medial : 0.2cm.lateral : 2cm.deep : 0.5cm.representative sections are submitted.b) received fibrofatty tissue measuring 8 x 7 x 3.5 cm. largest lymph node measuring 2.4 x 2 x 1.2 cm. cut surface grey brown with fatty infiltration.,section shows no residual tumor. treatment related changes are seen including lymphoplasmacytic infiltrate foamy macrophages pigment laden macrophages extensive areas of hyalinisation and fibrosis.,a) left breast left breast conservative surgery(post lumpectomy and post chemo) :no residual tumor seen.complete response to treatment is seen. therapy related changes noted. all margins of resection are free of tumour.b) left axillary lymph node dissection :isolated fourteen lymph nodes all are free of tumor (0 14).pathological stage : ypt0n0
MR160005682,left beast lump carcinoma.,left breast biopsy.,received 4 grey white linear cores measuring 1 to 1.3cm.entire tissue processed.,linear cores of breast parenchyma with cellular lesion arranged as nests sheets and cords. the cells have irregular hyperchromatic nucleus inconspicuous nucleolus and moderate amount of cytoplasm. mitotic figures are discerned.,invasive ductal carcinoma left breast biopsy.modified br score is 7 9 grade ii.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160005694,thick walled cystic lesion in left breast carcinoma breast.,biopsy from left breast.,received multiple grey white to grey brown linear cores measuring 0.7 to 1.2cm.,section shows cores of tissue harboring a lesion arranged in cords and sheets. individual cells are pleomorphic with hyperchromatic nuclei of varying sizes with irregular borders few with prominent nucleoli and moderate to abundant cytoplasm. mitotic figures are discerned. keratin pearls formation noted. stroma shows hyalinisation and lymphocytic infiltrates.,left breast core biopsy :invasive carcinoma with squamous differentiation grade 3. modified bloom richardson score is 8 (3+3+2).
MR160005733,mass in left breast carcinoma breast.,biopsy from left breast.,received 3 grey white to grey brown linear cores measuring 1.3 to 1.8cm.entire tissue processed.,linear cores of breast parenchyma harboring a neoplasm arranged as cords and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,invasive carcinoma biopsy from left breast.modified br score is 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures :1 6 9
MR160005824,carcinoma right breast.,a) right breast lumpectomy.b) right axillary clearance.,a) received lumpectomy specimen measuring 8 x 6.2 x 4.5 cm.skin ellipse measuring 6cm.one serial sectioning a greywhite lesion measuring 3 x 3 x 2.5 cm seen.located at the following distances from respective margins: superior margin 1cm.inferior margin 1.8cm.medial margin 1.5cm.lateral margin 2cm.deep margin 1.5cm.representative sections are submitted.b) received fibrofatty tissue measuring 10 x 5 x 4.3 cm largest lymph node measuring 2 x 1.5 x 1.2 cm cut surface shows tumor deposits. total isolated twenty four lymph nodes.,multiple sections from breast parenchyma show a neoplastic lesion arranged in cords tubules nests and in diffuse sheets.tumor cells display vesicular nuclei prominent nucleoli and moderate cytoplasm. mitotic figures discerned. peritumoral lymphocytic infiltration seen. lymphovascular and perineural invasion are identified.ductal carcinoma in situ is seen.,right breast lumpectomy :invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+2+3) tumor measures 3 cm in greatest dimension. lymphovascular invasion is identified. perineural invasion is identified. ductal carcinoma in situ of solid and comedo pattern with intermediate nuclear grade is seen. all margins of resection are free of tumor.lymph nodes : three out of twenty four lymph nodes show metastatic tumour deposits with extranodal extension(3 24). size of the largest tumor deposit measures 2 cm in greatest dimension.pathological stage : pt2n1asummary: right lumpectomy with right axillary clearance infiltrating ductal carcinoma grade 3.nodal metastases present(3 24).
MR160005825,known case of carcinoma left breast ( post bcs status),left breast lesion biopsy,received 3 linear cores measures 0.3 3cm. entire tissue processed.,section shows cores of fibro adipose tissue harboring invasive neoplasm in cords sheets and nests composed of cells with moderate cytoplasm hyperchromatic nuclei with moderate pleomorphism in a desmoplastic stroma.,left breast lesion biopsy:invasive carcinoma suggestive of recurrence
MR160005828,known case of carcinoma breast.,biopsy from c4 body.,received multiple grey white soft tissue bits altogether measures 2.5x2x0.5 cm 2grms. entire tissue processed.,sections shows fragments of fibrocollagenous tissue admixed with bony fragments and cartilagenous tissue.no evidence of metastatic deposits.,biopsy from c4 body :shows mature bony fragments and cartilagenous tissue.no evidence of malignancy in the sections studied.
MR160005846,right breast lump carcinoma.,right breast corebiopsy.,received 3 grey white to grey brown linear cores measuring 1.1 to 1.3cm. entire tissue processed.,linear cores of breast parenchyma harboring cellular lesion arranged as nests and sheets. the cells have irregular hyperchromatic nucleus few showing nucleoli and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160005893,mass in left breast carcinoma breast.,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 0.3 to 1c.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arrnanged as sheets islands and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. areas of necrosis seen including foci of high grade comedo ductal carcinoma in situ .,invasive ductal carcinoma biopsy from left breast.modified br score is 8 9 grade 3.tubule formation : 3nuclear pleomorphism : 2mitotic figures 3 8 9 foci of high grade comedo ductal carcinoma in situ seen.
MR160005908,mass in left breast carcinoma breast.,left breast biopsy.,received 3 grey white linear cores measuring 1 to 1.2cm.entire tissue processed.,linear cores of breast parenchyma comprising of neoplasm arranged as clusters sheets and occasional tubules. the neoplastic cells exhibit moderate nuclear pleomorphism and have moderate to abundant eosinophilic cytoplasm. mitotic figure are discerned.,infiltrating ductal carcinoma left breast biopsy.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160005934,mass in right breast carcinoma breast.,right breast mass core biopsy.,received 3 grey white to grey brown linear cores measuring 1 to 1.2cm.entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast mass core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160005938,mass in left breast carcinoma breast.,biopsy from left breast mass.,received multiple grey white to grey brown linear cores measuring 1 to 1.2cm.entire tissue is processed.,sections from the linear cores show tumor cells arranged in nests trabecular and sheets.cells have scanty to moderate cytoplasm with round to oval hyperchromatic nuclei.stroma is desmoplastic.,left breast mass biopsy :invasive ductal carcinoma grade 2.modified br score is 6 9.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR160005999,mass in left breast.,biopsy from left breast mass.,received multiple grey white to grey brown linear cores measuring 0.9 to 1.1 cm. entire tissue is submitted.,section shows cores of tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy : invasive ductal carcinoma grade 2. modified bloom richardson score is 6 (3+2+1).
MR160006028,left breast lump carcinoma.,biopsy from left breast.,received 5 greywhite to greybrown linear cores measuring 1.2 to 1.5cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as tubules and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclear conspicuous nucleoli and moderate cytoplasm. the intervening stroma is desmoplastic.,biopsy from left breast:infiltrating ductal carcinoma.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 7 9
MR160006090,mass in left breast galactocele. carcinoma breast.,biopsy from left breast mass.,received multiple grey white soft tissue bits measuring 0.4x0.3x0.1cm.entire tissue is processed.,section shows breast parenchyma showing occasional ducts lined by bilayered epithelial cells.stroma shows fibrosis and infiltration by chronic inflammatory cells.areas of necrosis see.,left breast mass biopsy :necrotic lesion.no definite opinion is possible.suggest repeat biopsy.
MR160006095,right breast lump carcinoma.,biopsy from right breast.,received 4 greywhite to greybrown linear cores measuring 0.2 to 1.3cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters cords and islands. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm lymphovascular emboli seen.,biopsy from right breast:infiltrating ductal carcinoma.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160006121,mass in left breast carcinoma breast.,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 0.7 to 1cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged in tubular pattern and cords . the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm.the intervening stroma is desmoplastic. focus suggestive of solid ductal carcinoma in situ noted.,biopsy from left breast:infiltrating ductal carcinoma.modified br score is 6 9 grade 2tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR160006158,multiple skeletal secondary deposits.left breast mass carcinoma.,left breast mass.,received multiple grey white to grey brown soft tissue bits measuring 0.7 to 0.8cm.entire tissue is processed.,section shows linear cores of breast parenchyma harboring cellular lesion arranged as tubules nests and cords.the cells have hyperchromatic nucleus inconspicuous nucleolus and moderate amount of cytoplasm.mitotic figures are discerned.,invasive ductal carcinoma grade i.tubule formation 2nuclear pleomorphism 2mitotic figures 1 5 9
MR160006175,mass in left breast carcinoma breast.,biopsy from left breast lesion.,received multiple grey white linear cores measuring 1.2 to 1.3cm.,section shows linear cores with tumor cells arranged in nests and sheets.cells are pleomorphic nuclei.stroma shows lymphoplasmacytic infiltration.extensive areas of necrosis present.,left breast lesion biopsy : invasive ductal carcinoma grade 2.modified bloom richardson score 7 (3+2+2).areas of necrosis is seen.
MR160006187,complaint o right carcinoma breast lumpectomy done outside.,right mrm.,received in : formalinprocedure : modified radical mastectomy laterality : righttotal dimensions : medial lateral 18cm superficial deep 3cm superior inferior 18cmskin ellipse : 11x6cm nipple : normal scar surgical defect : measures 5cm in lengthtumor : no obvious tumor seen(lumpectomy bed)consists of cystic areas and fibrotic areas measures 4.5x3x2cm location of tumor : center line quadrant deep margin : 0.5cm muscle : absent adjacent breast : fibrofatty tissue axillary tail : 7x5x2.5cm.total number of nodes : 15 lymph nodessize of largest node : 2x1.2x1cm cut surface shows grey brown to grey white,right breast right modified radical mastectomy: tumor bed: no residual viable tumor present.areas of fibrosis necrosis inflammatory cells foreign body giant cells and granulation tissue present. fibrotic area measuring 4.5cm in greatest dimension and is located in the central quadrant. posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: 15 lymph nodes show no deposits of tumor.,right mrm post lumpectomylumpectomy bed: no residual tumor present. fibrosis necrosis inflammatory cells and foreign body giant cells and granulation tissue present.nodal metastases 15 nodes show no deposits of tumor.
MR160006199,mass in left breast carcinoma breast.,biopsy from left breast mass.,received multiple grey white linear core measuring 1.2 to 1.4cm.entire tissue is processed.,section from the linear cores show breast parenchyma harboring a neoplastic lesion with cells arranged in nests trabecular and sheets.cells are pleomorphic with round to oval hyperchromatic infiltration.extensive area of necrosis present.,left breast mass biopsy : invasive ductal carcinoma grade 2.modified bloom richardson score is 6 (2+3+1).extensive areas of necrosis present.
MR160006205,case of lump in left breast carcinoma left breast.,left breast.,received 2 grey white linear cores measuring 1.2 to 1.4cm.entire tissue processed.,section shows cores of breast tissue harboring a lesion arranged in tubules cords and nests. individual cells have round o oval hyperchromatic nuclei inconspicuous nucleoli and scanty cytoplasm. mild nuclear pleomorphism seen. mitotic figures discerned. stroma shows fibrosis and hyalinisation.,infiltrating ductal carcinoma grade 2modified br score is 7 9.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 3 7 9
MR160006226,right breast lump carcinoma.,biopsy from right breast lump.,received 4 grey white to grey brown linear cores measuring 1 to 1.3cm. entire tissue processed.,multiple linear cores from breast shows tumor arranged in trabeculae and as glands. the cells have moderate cytoplasm and round to oval hyperchromatic nuclei. mitotic figures are seen lt 5 10 hpf. focal myxoid areas seen,biopsy from right breast:infiltrating ductal carcinoma.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160006238,small 1x1cm lesion in left breast (12 0 clock) carcinoma.,biopsy from left breast lesion.,received 6 greywhite to greybrown linear cores measuring 0.4 to 0.8cm. entire tissue processed.,section shows linear trucut cores with sheets and poorly cohesive clusters of cells with pleomorphic hyperchromatic nuclei moderate to abundant eosinophilic cytoplasm. mitotic figures are discerned.,invasive ductal carcinoma nos grade 2 biopsy from left breast lesion.tubule formation : 3nuclear pleomorphism : 3mitotic figures : 1 7 9
MR160006240,right breast lump carcinoma.,biopsy from right breast lump.,received 4 greywhite to greybrown linear cores measuring 0.7 to 0.8 cm. entire tissue processed.,section linear cores of breast parenchyma with extensive areas of dcis consisting of solid and comedo necrosis type. a foci suspicious of invasion noted. stroma show desmoplasia and lymphoid aggregated and stromal cells congested hyalinised blood vessels noted.,right breast core biopsy:ductal carcinoma in situ of cribriform and comedo pattern with intermediate nuclear grade is seen with suspicious foci of invasion.
MR160006261,solid cystic lesion in left breast carcinoma phylloides tumor.,biopsy from left breast lesion.,received multiple grey white to grey brown soft tissue bits altogether measuring 0.7x0.6x0.3cm. entire tissue is processed.,section shows linear trucut cores showing a papillary lesion with fibrovascular cores lined by pleomorphic cells with hyperchromatic nuclei and inconspicuous nucleoli. mitotic figures are discerned.,papillary neoplasm nuclear grade ii.suggest wide local excision.
MR160006302,left breast lump carcinoma.,left breast lump core biopsy.,received 4 greywhite to greybrown linear cores measuring 1 to 1.2 cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets. individual cells have hyperchromatic nuclei prominent nucleoli and moderate amount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 3. modified bloom richardson score is 8 (3+2+3).
MR160006370,carcinoma right breast.,a) right breast lump wide local excision.b) right axillary lymph nodes lymph node dissection.,a) received lumpectomy specimen measures 5x5.5x2.5cm. cut surface shows grey white lesion measures 2x2x1.2cm. overlying skin ellipse measures 3x2cm. located at the following distances from the respective margins: superior margin 1.1cminferior margin 2cmlateral margin 1.3cmmedial margin 1cmdeep margin 0.5cmb) received single fibrofatty tissue measures 12x6x2cm. largest lymph node measures 1.4x1.4x0.4cm. 16 lymph nodes isolated.,histopathologically examined section shows breast parenchyma harboring a lesion arranged in nests cords and trabeculae. individual cells have moderately pleomorphic nuclei hyperchromatic with inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm with irregular borders. mitotic figures discerned. stroma shows fibrosis and hyalinisation and lymphocytic infiltrate. areas of necrosis seen. ductal carcinoma insitu with comedonecrosis seen.,a) right breast lump wide local excision :invasive ductal carcinoma grade 2.tubule formation 2nuclear pleomorphism 2mitotic activity 3mbr score 7 9. all margins of resection are free of tumor. ductal carcinoma in situ is present with comedonecrosis. lymphovascular invasion is not identified. perineural invasion is not identified. adjacent breast shows fibrosis.b) right axillary lymph nodes lymph node dissection : 16 lymph nodes isolated all are free of tumor(0 16). they show reactive hyperplasia.
MR160006397,mass in left breast carcinoma breast.,biopsy from left breast mass.,received 5 linear fragments ranging from 0.4 to 0.5cm.entire tissue is processed.,section shows hyperplastic ductules seen in papillary pattern lined by tall columnar epithelial cells with fibrovascular core.no definite evidence of invasive malignancy is seen.,left breast mass biopsy : suggestive of papillary lesion.suggest excision of the lump for further confirmation.
MR160006420,mass in left breast carcinoma breast.,left breast biopsy.,received 3 grey white to grey brown linear cores measuring 0.8 to 1.2cm.entire tissue processed.,section shows cores of breast tissue favoring a neoplasm arranged in nests and clusters.the cells have moderately pleomorphic dark nucleus with irregular nuclear membrane and moderate amount of eosinophilic cytoplasm. areas of necrosis seen. stroma shows fibrosis and hyalinisation along with lymphoplasmacytic infiltrate.,infiltrating ductal carcinoma left breast biopsy.modified br score is 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160006437,right breast lump carcinoma.,biopsy from right breast lump.,received 4 greywhite to greybrown linear cores measuring 0.6 to 1.5cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as islands tubules and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. lymphovascular emboli seen. small focus of necrosis noted.,invasive ductal carcinoma biopsy from right breast lump.modified br score : 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 lymphovascular emboli seen.
MR160006479,small spiculated lesion in left breast (12 o clock) .,biopsy from left breast.,received 7 grey white to grey brown linear cores measuring0.5 to 0.7cm. entire tissue processed.,section shows cores of breast tissue harboring a lesion arranged in clusters nests and singly scattered. cells have mildly pleomorphic hyperchromatic nucleus with irregular borders inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. stroma shows fibrosis and hyalinisation.,biopsy from left breast:infiltrating ductal carcinoma.modified br score is 5 9 grade 2tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9
MR160006527,complaint of right breast lump.,a) right breast lumpectomy.b) right modified radical mastectomy.,a) received lumpectomy specimen measures 3.5x1.5x1.5cm. cut surface shows grey white area measures 2.5x1.2x1.2cm. distance from inked margin 0.1cmb)total dimensions : medial lateral 13cm superficial deep 3cm superior inferior 13cm skin ellipse : 12x7cm nipple : unremarkable.scar : measures 3.5cm in length in the outer quadrant tumour size : lumpectomy bed shows fibrotic and firm areas deep margin : is 1cm from the lumpectomy bed muscle : absent adjacent breast : fibrofatty tissue axillary tail : 5x4x3cmsize of largest node : 1.3x1x0.8cm,a) sections from tumor show breast parenchyma infiltrated by a neoplasm arranged as clusters and tubules. the neoplastic cells have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. areas with mucin pools with tumor clusters floating in them are seen.areas of solid and cribriform intermediate to high grade ductal carcinoma in situ and lobular cancerisation seen.b) lumpectomy bed harbors small volume of ductal carcinoma in situ. no residual invasive component seen. nipple and areola free of tumor.deep margin free of tumor17 axillary lymph nodes isolated are free of tumor.,a) right breast lumpectomyinvasive ductal carcinoma with mucinous featurestumor size : 2.5x1.2x1.2cmgrade ii (7 9)tubule formation 3 nuclear pleomorphism 2mitotic figures 2 7 9 foci of ductal carcinoma in situ(intermediate to high grade seen)b) right modified radical mastectomy: lumpectomy bed shows small volume of ductal carcinoma in situ.nipple and areola : free of tumor.deep margin : free of tumor.17 right axillary lymph nodes isolated are free of tumor.
MR160006548,left breast lump carcinoma.,biopsy from left breast lump.,received five greywhite to greyyellow linear cores measuring 0.6 to 1cm. entire tissue processed.,the studied section shows linear cores of breast parenchyma harboring a neoplasm arranged in tubules cords and in sheets exhibiting moderate nuclear pleomorphism. intervening stroma shows elastosis. mitoses are discerned.,invasive ductal carcinoma biopsy from left breast.modified br score : 6 9 grade 2.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR160006618,bilateral two breast lesion. bilateral axillary lymph nodes.,biopsy from right breast lesion.,received 4 grey white to grey brown linear cores measuring 0.8 to 1.3cm. entire tissue processed.,section sows linear cores of breast parenchyma harboring a neoplastic lesion arranged as diffuse sheets and dispersed pleomorphic cells with hyperchromatic round to oval nucleus moderate nuclear atypia and moderate cytoplasm. atypical mitotic figures seen.,biopsy from right breast lesion:invasive ductal carcinoma. grade 2.modified bloom richardson score 6 9.tubule formation 3 nuclear pleomorphism 2mitotic figures (4 5 10hpf) 1 6 9
MR160006671,left breast mass carcinoma.,biopsy from left breast.,received five grey white to grey brown liner cores measuring 0.6 to 1cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged in cords. the lesional cells have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,invasive carcinoma biopsy from left breast.modified br score is 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160006684,case of left carcinoma breast post lumpectomy.,a) left breast wide local excision.b) left axillary lymph nodes.,a) received lumpectomy specimen measures 12x7x4cm.overlying skin measures 10x3cm ad necrotic cut surface shows fibrotic grey white areas measures 3.3x3x2.5cm.located at the following distances from the respective margins : superior margin 3cminferior margin 2cmmedial margin 1.5cmlateral margin 2.5cmdeep margin 1.2cmb) received fibrofatty tissue measures 7x5x3cm. largest lymph node measures 2.8x2x1.8cm. cut surface shows grey white appearance.,a) section shows proliferating glands lined by cuboidal epithelium with bland nuclear features. few ducts are dilated and filled with inspissated eosinophilic secretions.post operative changes seen comprising of inflammatory cells consisting of lymphocytes plasma cells histiocytes and multinucleate foreign body giant cells seen.foamy macrophages noted.stroma shows fibrosis with bland stromal cells and inflammatory cells.few hyalinised and dilated blood vessels seen.areas of hemorrhage noted.b) section show lymph nodes with few reactive follicles sheets of histiocytes and dilated congested blood vessels.,a) left breast wide local excision : fibroadenosis. no residual tumor seen. adjacent tissue shows post operative changes like foreign boidy granulomata and fibrosis. all margins of resection are free of tumor. overlying skin is free of tumor.b) left axillary lymph nodes :17 lymph nodes isolated show no tumor deposits (0 17).they show reactive hyperplasia.
MR160006695,carcinoma left breast.,a) wide local excision.b) axillary lymph node dissection.,a) received lumpectomy specimen measures 11x8x5.5cm cut surface shows grey white nodular mass measures 3.8x3x3.3cm.small nodule measures 0.7x0.4x0.3cm present near the inferior margin (which is 1cm from the inferior margin) and is located 4cm from the larger nodule.superior margin 0.9cminferior margin 3.5cmmedial margin 2cmlateral margin 3.5cmdeep margin 1cmsuperficial margin 1.5cmb) axillary lymph node dissection :received fibrofatty tissue measures 6x3x2cm largest lymph node measures 1.5x1xcm cut surface shows grey white to grey brown.,a) tumor consisting of biphasic pattern consisting of ducts lined with cuboidal epithelial cells and lining epithelium shows stratification of cells with outer myoepithelium. the stroma shows spindle to oval cells. occasional mitotic figures are present less than 3 10 hpf. no pleomorphism or hyperchromasia of cells phylloides tumor.lymphovascular invasion is not present.resected margins superior margin free of tumorinferior margin free of tumor.medial margin free of tumor.lateral margin free of tumor.deep margin free of tumor.smaller nodule present at the inferior margin shows fibroadenoma.b) axillary lymph node dissection : 16 nodes show no deposits of tumor.,a) wide local excision :breast mass with phylloides tumor benignall resected margins are free of tumor.small nodular mass present with fibroadenoma.b) axillary lymph node dissection:16 nodes no deposits of tumor.
MR160006752,right breast lump carcinoma.,biopsy from right breast.,received four grey white to grey brown linear cores measuring from 0.5 to 1cm.entire tissue processed.,linear cores of breast tissue showing neoplastic cells floating in lakes of mucin. also seen are neoplastic cells arranged in ductal pattern exhibiting moderate nuclear pleomorphism harboring vesicular nuclei and moderate cytoplasm. occasional atypical mitosis noted.,invasive carcinoma with mucinous component biopsy from right breast.modified br core is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160006766,complaint of left carcinoma breast.,a) left sentinel lymph node biopsy.b) wide local excision of the lumpectomy.,a) received fibrofatty tissue measures 4x2x0.5cm.2 lymph nodes isolated. large lymph node isolated measures 1.2x1x0.8cm.cut surface shows grey yellow to grey white.b) received fibrofatty tissue measures 6x7x3cm.cut surface shows grey white lesion measures 2x1.3x1.2cm.overlying skin ellipse measures 3.5x2cm. located at the following distances from the respective margins: superior margin 2.5cminferior margin 2cmmedial margin 0.6cmlateral margin 3.5cmdeep margin 1cm,a) left sentinel lymph node :2 nodes show reactive hyperplasia no deposits of tumor present.b) wide local excision of the lumpectomy :tumor tumor is composed of pleomorphic cells with hyperchromatic nucleus and scanty cytoplasm.tubule formation lt 10 3nuclear pleomorphism 8 10 2mitotic figures 2 mbr score 7 9 nuclear grade iilymphovascular invasion is not present.ductal carcinoma insitu is not present.resected margins superior margin free of tumor.medial margin free of tumor.inferior margin free of tumor.lateral margin free of tumor.deep margin free of tumor.,a) left sentinel lymph node :2 nodes show no deposits of tumor.b) wide local excision of the lumpectomy :invasive ductal carcinoma.maximum dimension of tumor 3.5x2cm nuclear grade ii.ductal carcinoma in situ is not present.lymphovascular invasion is not present.all resected margins are free of tumor.
MR160006796,carcinoma right breast post nact.,a) wide excision of right breast lump.b) revised medial margin.c) axillary lymph nodes.d) completion mastectomy.,a) lumpectomy breast conservative surgery:received lumpectomy specimen measuring 5.5x5.5x2.5cm.cut surface : an irregular greywhite lesion measuring 1.4x0.8x1.3cm.located at the following distances from respective margins: superior margin 1.5cm.inferior margin 0.5cm.medial margin 0.3cm.lateral margin 2.5cm.deep margin 1.3cm.b) revised medial margin:received fibrofatty tissue measuring 7x2.5x2cm one surface inked blue.cut surface : an ill defined greywhite lesion measuring 3.5x1.5x1cm.distance from inked surface is lt 0.1cm.c) axillary lymph nodes dissection:received fibrofatty tissue measuring 6x5x2.5cm largest lymph node measuring 2.3x1.8x1cm cut surface : fatty infiltration.total isolated 10 lymph nodes.d) received in : formalin fresh procedure : completion mastectomy.laterality : right. total dimensions : medial to lateral 17cm superficial to deep 4cm superior to inferior 19cmskin ellipse : 14x6.5cm. nipple : normal scar surgical defect : 3.5x1.5cm located 4cm lateral to nipple.tumor : lumpectomy cavity measuring 6x6x3.5cm tumour size : no residual solid tumor present. location of lumpectomy cavity: upper outer quadrant. margins of tumor : fibrofatty. deep margin : 0.8cmmuscle : absent adjacent breast : fibrofatty tissue. axillary tail : not present.,a) wide excision of right breast lump:tumor:the sections show residual viable tumor.invasive ductal carcinoma.surrounding the tumor areas of fibrosis necrosis focal areas of calcification and cystically dilated glands.grade:tubular formation : 3mitotic figures: 2anaplasia : 2mbr score is 7 9.nuclear grade:iiductal carcinoma in situ : not present.lymphovascular invasion: present.perineural invasion : not present.resected margins:superior margin free of tumor.inferior margin free of tumor.medial margin involved by tumor.lateral margin free of tumor.deep margin free of tumor.b) revised medial margin:shows invasive ductal carcinoma involved by the tumor.c) axillary lymph nodes:3 nodes show foci of metastatic deposits of viable invasive ductal carcinoma out of 10 nodes.d) completion mastectomy:lumpectomy cavity shows fibrofatty tissue with cystically dilated ducts focal haemorrhagic areas are present.no evidence of residual tumor.resected margin:all resected margins are free of tumor.undersurface resected margin free of tumor.nipple and areola : unremarkable.,breast conservative surgery:residual viable tumor present.invasive ductal carcinoma measuring 1.4x1.3x0.8cm.nuclear grade : ii.ductal carcinoma in situ : not present.residual margin superior inferior lateral and deep margins : free of tumor.medial margin : invaded by tumor.revised medial margin : invaded by tumor.mastectomy lumpectomy bed:no residual tumor present.all resected margins : free of tumor.nipple and areola : unremarkable.
MR160006808,left breast lump carcinoma.,biopsy from left breast lump.,received 4 grey white to grey brown linear cores measuring 0.8 1.2cm. entire tissue processed.,section shows cores of breast tissue harboring a lesion arranged in nests cords and trabeculae . neoplastic cells have mild to moderately pleomorphic nucleus with scanty to moderate cytoplasm. mitotic figures are discerned.,biopsy from left breast lump:invasive ductal carcinoma. grade 2.modified blood richardson score 7 9tubule formation 3 nuclear pleomorphism 2 mitotic figures 2 7 9
MR160006863,right breast lump carcinoma,right breast lump biopsy.,received 3 grey white to grey brown linear cores measuring 0.3 to 1.4cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160006874,its defined to mass in right breast .,biopsy from right breast.,received 5 grey white to grey brown linear cores measuring 1 to 1.2cm. entire tissue processed.,the studied section show linear cores of breast parenchyma harboring neoplastic lesion. the neoplasm arranged in tubules and in chords with moderate pleomorphic hyperchromatic nuclei and eosinophilic cytoplasm. intervening stroma shows elastosis. mitosis are discerned,biopsy from right breast:infiltrate ductal carcinoma.modified bloom richardson score is 6 9 grade 2.tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR160006884,right breast lump carcinoma.,biopsy from right breast lump.,received 4 greywhite to greybrown linear cores measuring 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion. the neoplasm is arranged in tubules clusters with pleomorphc hyperchromatic nuclei with eosinophilic cytoplasm. the intervening stroma shows chronic inflammatory infiltrate comprising of plasma cells .areas of necrosis seen.,invasive ductal carcinoma biopsy from right breast.modified br score : 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160006911,right breast lump p o suspicious lesion.,right breast core biopsy.,received multiple fragment linear core measures 0.5 to 1.0 cm. entire tissue processed.,sections shows cores of tissue infiltrated by tumor cells in nests and diffuse sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160007027,known case of carcinoma right breast lump excision done 1 year back.now presented with recurrent lesion in right breast.,biopsy from right breast lump.,received multiple grey white to grey brown soft tissue bits altogether measures 1 to1.2cm. entire tissue processed.,section shows cores of breast tissue harboring a neoplastic lesion arranged in nests cords trabeculae and sheets. neoplastic cells are round to oval with hyperchromatic nuclei exhibiting moderate amount of pleomorphic nuclear exhibiting moderate amount of pleomorphism few with prominent nucleoli and scanty to moderate cytoplasm. mitotic figures discerned.,biopsy from right breast lump invasive ductal carcinoma grade iimbr score is 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR160007033,left breast mass carcinoma..,biopsy from left breast mass.,received 5 gery white to grey brown linear cores measures 0.5 to 1cm. entire tissue processed.,section shows cores of breast tissue infiltrated by a neoplastic lesion arranged in tubules nests and cords. cells exhibit mild to moderate nuclear pleomorphism prominent nucleoli and scanty to moderate amount of cytoplasm. mitotic figures discerned. stroma shows myxoid change and hyalinisation.,biopsy from right breast lump invasive ductal carcinoma grade imbr score is 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR160007034,right breast lump carcinoma.,biopsy from right breast lump.,received 5 grey white to grey brown linear core measures 0.6 to 1.2cm. entire tissue processed.,linear cores of cellular lesion arranged as nests and tubules. the cells have irregular hyperchromatic nucleus inconspicuous and moderate amount of cytoplasm.lymphovascular invasion not identified.ductal carcinoma in situ not seen.,invasive ductal carcinoma. right breast lump modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160007043,right breast lump carcinoma.,biopsy from right breast lump.,received 4 grey white to grey brown linear cores measures 0.7 to 1cm . entire tissue processed.,linear cores from breast shows tumor arranged in cords trabecular and as tubules showing cells with moderate to abundant amount of cytoplasm and having hyperchromatic nuclei moderate nuclear pleomorphism is noted. lymphovascular invasion is seen. mitotic figures are discerned (6 10hpf).,biopsy from right breast:invasive ductal ductal carcinoma.nuclear grade ii.modified bloom richardson score is 6 9.tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR160007064,right breast lesion carcinoma breast.,biopsy from right breast..,received multiple grey white grey brown linear cores measures 0.3 to 0.4cm. entire tissue processed.,linear cores from the breast tissue shows features of ductal carcinoma in situ showing solid cribriform and comedonecrosis pattern. intervening stroma is fibrocollagenous focal aggregates of lymphocytes are seen. foci of calcification noted.,right breast core biopsy :shows ductal carcinoma in situ of solid cribriform and comedonecrosis pattern with intermediate nuclear grade.no definite evidence of invasion is seen.
MR160007066,right breast lump carcinoma.,biopsy from right breast lump.,received multiple grey white to grey brown linear cores measures 0.5 to 1cm . entire tissue processed.,multiple linear cores from breast tissue shows lesion arranged tubules papillar trabeculae in cords. the cells have abundant cytoplasm slightly hyperchromatic nuclei and showing mild nuclear pleomorphism.many tubules are also showing secretory changes.,biopsy from right breast:suggestive of papillary lesion .the possibilities considered are 1. myoepithelial neoplasm 2. papillary neoplasm
MR160007075,lump in left breast retroareolar region.,a) left breast lump wide local excision.b) right breast lump wide local excision.,a) received lumpectomy specimen measuring 5.5x4x2.5cm cut surface shows greywhite ill defined lesion measuring 2.3x2x1.2cm.distance from margins: superior margin 1.8cm.inferior margin 1.5cm.medial margin 0.3cm.lateral margin 1cm.deep margin lt 0.1cm.b) received lumpectomy specimen measuring 5.5x5x2.3cm greywhite lesion measuring 0.9x0.5x0.4cm.distance from margins: superior margin 0.9cm.inferior margin 3.5cm.medial margin 1cm.lateral margin 1.3cm.deep margin lt 0.2cm.,a) sections reveal breast parenchyma demonstrating a papillary proliferation of cuboidal to columnar cells with vesicular nuclei and moderate amount of eosinophilic cytoplasm.mitotic figures are discerned.there are foci of apocrine metaplasia surrounding ducts show features of sclerosing adenosis microglandular and epithelial hyperplasia.all resected margins are free of tumor.b) sections exhibit breast parenchyma with ducts demonstrating proliferation of cuboidal to columnar cells in papillary configuration harboring vesicular nuclei and moderate amount of eosinophilic cytoplasm.all resected margins are free of tumor.,a) left breast lump wide local excision:papillary neoplasm suspicious of invasive papillary carcinoma.needs ihc.all resected margins are free of tumor.tumor size: 2.3cm in the greatest dimension.lymphovascular and perineural invasion are not identified.b) right breast lump wide local excision:papillary neoplasm.needs ihc.all resected margins are free of tumor.
MR160007097,carcinoma right breast.,biopsy from right breast mass .,received 5 grey white to grey brown linear cores measures 0.5 to 1cm . entire tissue processed.,linear cores from breast shows neoplastic lesion in few foci composed of atypical cells with abundant cytoplasm pleomorphic nuclei with prominent nucleoli. comedonecrosis is seen. also stroma is showing dense desmoplastic reaction and scanty inflammatory infiltrate..,biopsy from right breast mass:suggestive invasive ductal ductal carcinoma.nuclear grade 3.comedonecrosis seen.
MR160007154,left breast lump carcinoma.,trucut biopsy of left breast lump.,received multiple grey white to grey brown linear cores measures 0.3 to 1 cm. entire tissue is processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy : invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160007174,left chest wall lesion deposit.,biopsy from left chest wall lesion.,received multiple grey white linear core measures 0.3 to 0.4cm. entire tissue processes.,section studied shows cores of fibrous tissue harboring infiltrating lesion arranged in nests and cords. the cells are oval have marked pleomorphic hyperchromatic nuclei with inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. mitotic activity 3 4 10hpf. stroma shows desmoplasia.,left chest wall lesion biopsy :recurrent high grade carcinoma in a known case of carcinoma left breast.
MR160007236,carcinoma breast left post lumpectomy.,left modified radical mastectomy.,received in : formalin fresh procedure : mr mastectomy post lumpectomy.laterality : left. total dimensions : medial to lateral 12cm. superficial to deep 3cm. superior to inferior 13cm. skin ellipse : 9x7cm. nipple areola : unremarkable.scar : scar in upper central quadrant.tumor : greywhite nodule.tumour size : 1.5x1x1cm. location of tumor : upper central quadrant. minimum margin clearance from all tumor deposits (when multiple)specify which margin from which tumor eg nodule 1 nodule 2 etc)margins of tumor : ill defined. deep margin : 1cm.muscle : present absent adjacent breast : fibrofatty tissue. axillary tail : 5x4x2cm.total number of nodes : 23 (specify if sentinel nodes sent )size of largest node : 1.5x1x0.8cm cut surface:greybrown.,section show breast parenchyma with a lesion arranged in sheets.individual cells have round to oval vesicular nuclei and moderate amount of cytoplasm.lymphoid aggregatesand proliferating blood vessels seen.stroma is fibrous with stromal cells.mitotic figures discerned.perineural invasion not identified lymphovascular invasion is not identified.,left breast left modified radical mastectomy residual tumor status post lumpectomy.invasive ductal carcinoma grade ii.modified br score is 7 9tubule formation: 3nuclear pleomorphism: 2mitotic figures: 2residual tumor measures 1.5 cm in greatest dimension and is located in the upper central quadrant. lymphovascular invasion is not identified.perineural invasion is not identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: 23 lymph nodes isolated show no metastasis (0 23) show reactive hyperplasia.summary: left mrm invasive ductal carcinoma residual tumor status post lumpectomy grade ii.nodal metastases 0 23.
MR160007252,mass in left breast carcinoma breast.,biopsy from left breast.,received multiple grey whit to grey brown linear cores measures 0.6 to 1cm. entire tissue is processed.,section shows cores of breast parenchyma harboring a neoplasm arranged in nests and in diffuse sheets.. cells show moderate nuclear pleomorphism hyperchromatic nuclei moderate eosinophilic cytoplasm. mitotic figures discerned. areas of necrosis and hemorrhage noted.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score 6(3+2+1)
MR160007263,carcinoma right breast.,right breast right modified radical mastectomy.,received in : formalinprocedure : modified radical mastectomy. laterality : right. total dimensions : medial to lateral 18cm. superficial to deep 4cm. superior to inferior 17cm.skin ellipse : 12 x 6.5 cm. nipple : normalscar surgical defect : seen measuring 2.5 cmtumor : single.tumour size : 4.6 x 4.5 x 2.5 cm location of tumor : upper outer quadrant. minimum margin clearance from all tumor deposits (when multiple)specify which margin from which tumor eg nodule 1 nodule 2 etc)margins of tumor : ill defined. deep margin : 0.8cm.muscle : absent adjacent breast : fibrofatty tissue. axillary tail : 4 x 3 x 2 cm.total number of nodes : 17 nodes.size of largest node : 2 x 1.2 x 1 cm cut surface greywhite.representative sections are submitted.,section shows breast tissue showing an infiltrating lesion arranged vague tubules sheets nests and cords. individual cells show hyperchromatic nuclei prominent nucleoli and moderate amount of eosinophilic cytoplasm. extensive areas of solid and cribriform ductal carcinoma in situ seen. mitotic figures discerned. areas of necrosis seen. stroma shows extensive sclerosis and fibrocollagenous tissue. lymphovascular and perineural invasion are identified.,right breast right modified radical mastectomy : invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2). tumour is unifocal and is located in the upper outer quadrant. tumor measures 4.6 cm in greatest dimension and lymphovascular invasion is identified. perineural invasion is identified. ductal carcinoma in situ of solid and cribriform pattern with intermediate nuclear grade. nipple and areola are free of tumor. posterior resection margin is free of tumor and is 0.8 cm in greatest dimension.lymph nodes :ten out of seventeen lymph nodes show metastatic tumour deposit with extranodal extension(10 17). largest tumor deposit measures 1.5 cm in greatest dimension.pathological stage : pt2n3asummary: right mrm invasive ductal carcinoma grade 2.nodal metastases ten out of seventeen lymph nodes shows metastatic deposits of invasive carcinoma.
MR160007282,right breast lump for evaluation carcinoma right breast.,biopsy from right breast lump.,received 5 grey white to grey brown linear cores measures 1.2x1.4cm. entire tissue processed.,section show breast parenchyma wi3th focal adenosis epitheliosis columnar cell change stroma shows marked neutrophilic infiltrate histiocytes and thin walled blood vessels.,biopsy from right breast lump:benign breast disease with acute inflammation
MR160007370,carcinoma right breast.,right breast right modified radical mastectomy.,received in : formalinprocedure : modified radical mastectomy laterality : righttotal dimensions : medial to lateral :19cm. superficial to deep : 4.5cm. superior to inferior :15cm.skin ellipse : 17x10cm. nipple areola : normal scar surgical defect : not seen.tumor : singletumour size : 3.7 x 3.2 x 3 cm. location of tumor : retroareolar in central quadrant.margins of tumor : ill defined deep margin : 2.9muscle : absent adjacent breast : fibrofatty tissue . axillary tail : 8 x 5 x 3 cm.total number of nodes : 23size of largest node : 1.4x1x1cm.representative sections are submitted.,section shows tumor arranged in nest clusters and glands. individual cells have moderate amount of cytoplasm with vesicular nuclei and prominent nucleoli. lymphovascular invasion is not identified. perineural invasion is not identified.,right breast right modified radical mastectomy : invasive carcinoma with neuroendocrine differentiation. modified bloom richardson score is 6(3+2+1). tumour is unifocal and is located in the central quadrant. tumor measures 3.7 cm in greatest dimension. lymphovascular invasion is identified. perineural invasion is not identified. ductal carcinoma in stu is identified of solid pattern with intermediate nuclear grade. posterior resection margin is free of tumor. nipple and areola is unremarkable.lymph nodes: one out of twenty seven lymph nodes shows metastatic tumor deposits with extranodal extension(1 27). tumor focus measuring 1.4 cm in greatest dimension.summary : right breast modified radical mastectomy : invasive carcinoma with neuroendocrine differentiation.lymph nodes: one out of twenty seven lymph nodes shows metastatic tumor deposits with extranodal extension(1 27).pathologist stage : pt2n1a
MR160007380,mass in right breast carcinoma breast.,right breast mass biopsy.,received 2 grey white to grey brown linear cores measuring 1 to 1.2cm.entire tissue processed.,section shows breast parenchyma showing few areas infiltrated by atypical cells arranged in tubules and nests lying in pools of mucin. individual cells have mild to moderately pleomorphic hyperchromatic nuclei with moderate cytoplasm. adjacent stroma shows few dilated ducts and adenosis admixed with foci of calcification.,right breast mass biopsy :invasive carcinoma with mucinous features grade 2. modified bloom richardson score is 6(3+2+1).
MR160007406,carcinoma right breast post opright axillary mass metastatic,biopsy of right axillary mass,received multiple grey white to grey brown linear cores measures 0.6 to 1cm. entire tissue is processed,section shows cores of tissue infiltrated by tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. areas of necrosis are seen,right axillary mass biopsy (post op carcinoma breast) :positive for malignancy.suggestive of metastatic carcinoma in known and treated case of carcinoma right breast.
MR160007420,mass in left breast carcinoma breast.,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 0.7 to 1cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as islands and cords. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. probable lymphovascular emboli seen.,invasive carcinoma biopsy from left breast.modified bloom richardson score is 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160007456,mass in right breast carcinoma breast.,biopsy from right breast.,received 4 grey white to grey brown linear cores measuring 1 to 1.2cm.entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as sheets and cords. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. mitoses are discerned. areas of necrosis seen. crush artifacts seen.,invasive ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160007528,case of lump in left breast carcinoma left breast.,biopsy from left breast.,received 4 greywhite to greybrown linear cores measuring 1 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as glands and cords. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic to vesicular nuclei conspicuous nucleoli and moderate cytoplasm. focus of high grade solid comedo dcis noted.,infiltrating ductal carcinoma biopsy from left breast.modified br score : 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160007529,mass in left breast carcinoma breast.,left breast mass.,received 4 grey white to grey brown linear cores measuring 0.8 to 1.2cm. entire tissue is processed.,section shows cores of fibrocollagenous tissue harboring cellular lesion arranged as nests. the cells have hyperchromatic nuclei inconspicuous nucleoli and moderate amount of cytoplasm. extensive areas of elastosis noted.,invasive ductal carcinoma grade 2.tubule formation 03nuclear pleomorphism 02mitotic figures 01 mbr score 6 9
MR160007543,carcinoma left breast post surgery left chest wall lesion deposit.,biopsy from left chest wall lesion.,received multiple grey white linear cores measures 0.6 to 1cm. entire tissue is processed.,linear cores of tissue exhibiting a neoplastic lesion arranged in sheets nests consisting of round to oval cells demonstrating moderate to marked nuclear pleomorphism eosinophilic cytoplasm in a desmoplastic stroma. there are foci of necrosis.,biopsy from left chest wall lesion :high grade malignancy the features are suggestive of metastatic deposits in a known case of carcinoma breast.suggest ihc.
MR160007560,mass in right breast carcinoma breast.,right breast biopsy.,received 5 grey white to grey brown linear cores measuring 0.6 to 0.8cm.entire tissue processed.,section shows cores of breast parenchyma infiltrated by a lesion arranged in nests sheets and cords exhibiting moderate to marked nuclear pleomorphism hyperchromasia prominent nucleoli and moderate amount of cytoplasm.areas of hemorrhage and necrosis seen.,right breast biopsy :invasive ductal carcinoma grade 2.modified br score is 6 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160007612,mass in right breast carcinoma breast.,biopsy from right breast mass.,received 4 greywhite linear cores measuring 1 to 1.5cm. entire tissue processed.,section shows cores of fibrofatty tissue with a neoplasm arranged in tubules and in sheets. cells display moderate nuclear pleomorphism hyperchromatic nuclei and moderate eosinophilic cytoplasm. mitotic figures discerned.,invasive ductal carcinoma grade ii.mbr score : 6 9.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR160007621,mass in right breast carcinoma breast.,biopsy from right breast mass.,received 3 greywhite linear cores measuring 0.5 to 0.8cm. entire tissue processed.,section shows scanty tissue composed of cores of fibrofatty tissue with focal areas showing a neoplasm arranged in tubules. cells displaying hyperchromatic nuclei and moderate cytoplasm. foci of dcis seen.,biopsy from right breast mass:suggestive of invasive ductal carcinoma nuclear grade ii.
MR160007638,mass in left breast carcinoma breast.,biopsy from left breast mass.,received 3 greywhite to greybrown linear cores measuring 0.3 to 1.2cm. entire tissue processed.,section shows cores of breast parenchyma harboring a neoplasm arranged in diffuse sheets and cords. cells display moderate nuclear pleomorphism vesicular nuclei prominent nucleoli and moderate eosinophilic cytoplasm. stroma shows desmoplasia and haemorrhage.,biopsy from left breast mass:invasive ductal carcinoma grade ii.modified br score : 7 9.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 3 7 9
MR160007786,known case of carcinoma right breastright axillary node with thickened cortex,biopsy from right axillary node,received multiple grey white linear cores measures 1.2 to 1.4cm. entire tissue processed.,linear cores of lymphoid tissue infiltrated by a cellular neoplastic lesion consisting of round to oval cells with pleomorphic vesicular nuclei eosinophilic cytoplasm and brisk mitotic activity.,biopsy from right axillary nodethe features favor metastatic deposits in a known case of carcinoma breastsuggest ihc.
MR160007889,mass in right breast carcinoma breast.,biopsy from right breast.,received 4 grey white to grey brown linear core measuring 0.7 to 1cm.entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as trabeculae clusters and sheets. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,invasive carcinoma biopsy from right breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160007920,mass in right breast carcinoma breast.,biopsy from right breast.,received 3 greywhite to greybrown linear cores measuring 0.7 to 1cm. entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as tubules islands and cords. the neoplastic cells have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is fibrotic. focus of solid dcis noted.,infiltrating ductal carcinoma biopsy from right breast.modified br score : 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160008056,right axillary nodes metastatic.,biopsy from right axillary nodes.,received multiple grey white linear cores measures 1.2 to 1.5cm. entire tissue is processed.,linear cores of tissue exhibiting cellular sheets and cords of round to ovoid neoplastic cells harboring pleomorphic vesicular nuclei and moderate amount of eosinophilic cytoplasm. there are interspersed vascular channels and residual lymphoid tissue.,biopsy from right axillary lymph nodes: metastatic deposits of adenocarcinoma. from breast.suggest ihc.
MR160008058,mass in right breast carcinoma breast.,biopsy from right breast.,received 4 grey white to grey brown linear cores measuring 0.5 to 0.7cm. entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as sheets. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. areas of necrosis seen.,invasive ductal carcinoma biopsy from right breast.modified br score is 8 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 areas of necrosis seen.
MR160008247,left breast mass carcinoma.,biopsy from left breast.,received 2 grey white linear cores measuring 1.2 to 1.5cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters islands cords and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is fibrous.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160008259,mass in right breast carcinoma breast.,biopsy from right breast.,received 2 grey white tiny linear cores measuring 0.3 to 0.4cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters tubules and islands. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is fibrotic.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160008262,left breast mass.,biopsy from left breast.,received six grey white to grey brown linear cores measuring 0.8 to 1cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords tubules and clusters.the neoplastic cells have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is fibrous.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160008277,patient presented with ulcerated growth over left breast 3months.,biopsy from ulcer over left breast.,received 2 grey white soft tissue bits large measuring 1.4x1x0.9cm.smaller measuring 0.8x0.8x0.6cm. entire tissue processed.,section shows skin with underlying neoplasm arranged as clusters and trabeculae. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. mitoses are discerned. the intervening stroma is scant.,infiltrating ductal carcinoma biopsy from ulcer over left breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160008288,right axillary node metastatic.,biopsy from right axillary node.,received 4 grey white linear cores measuring 1 to 1.3cm.entire tissue processed.,linear cores of lymphoid tissue infiltrated by dyscohesive nest cords islands of polygonal to oval cells harboring pleomorphic hyperchromatic nuclei and abundant eosinophilic cytoplasm amidst a desmoplastic stroma. mitosis are seen.,biopsy from right axillary node :metastatic carcinoma. from breast.suggest ihc.
MR160008291,lump left breast 3 months.,left breast left modified radical mastectomy.,received in : formalin.procedure : modified radical mastectomy.laterality : left total dimensions : medial to lateral : 17cm. superficial to deep : 3cm. superior to inferior :14cm.skin ellipse : 13x7cm. nipple areala : unremarkable. scar surgical defect : not seen.tumor : single.tumour size : 2.8x1.6x1.3cm. distance to nearest separate tumor foci (when multiple ):location of tumor : upper outer quadrant.margins of tumor : illdefined. deep margin : 0.5muscle : absent adjacent breast : fibrofatty tissue. axillary tail : 5x5x2cmtotal number of nodes : 17size of largest node :2.8x2x1.5cm.cut surface grey white.,section shows tumor cells i nests diffuse sheets and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular invasion is identified. perineural invasion is indeterminate.,left breast left modified radical mastectomy : invasive ductal carcinoma grade2. modified bloom richardson score is 6(3+2+1). tumor is unifocal and is located in the upper outer quadrant tumor measures 2.8 cm in greatest dimension. lymphovascular invasion is identified. perineural invasion is indeterminate. nipple and areola are free of tumor. posterior resection margin is free of tumor. lymph nodes :eleven out of fifteen lymph nodes show metastatic tumour deposits with extranodal extension(11 15). size of the largest tumor deposit measures 1.5 cm in greatest dimension.pathological stage : pt2n3asummary :left breast left modified radical mastectomy: invasive ductal carcinoma grade 2.lymph nodes:15 lymph nodes metastasis: 11 (11 15).
MR160008304,mass in right breast carcinoma breast.,biopsy from right breast.,received multiple grey white to grey brown linear cores measures 1.2 to 1.5cm. entire tissue is processed.,linear cores from breast shows tumor arranged in cords sheets and focally tubules. the cells have moderate amounts of eosinophilic cytoplasm with round to oval hyperchromatic nuclei. there is moderate pleomorphism. focal lymphocytic infiltrate is noted.,right breast biopsy :invasive ductal carcinoma grade i.mbr score 6 (3+2+1).tubule formation 3nuclear pleomorphism 2mitotic figures 1
MR160008309,mass in right breast carcinoma breast.,biopsy from right breast.,received three grey white to grey brown linear cores measuring 1 to 1.2cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as islands and nests. the neoplastic cells have hyperchromatic nuclei and moderate cytoplasm.areas of necrosis seen.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160008332,right breast lump carcinoma.,biopsy from right breast lump.,received 5 grey white to grey brown linear cores measuring 0.6 to 1cm.entire tissue processed.,linear cores of breast tissue showing focus of usual ductal hyperplasia and multiple foci harboring lymphoplasmacytic inflammatory cell infiltrate.,no definite evidence of malignancy in the cores submitted.kindly correlate with clinical and mammography findings and suggest repeat if deemed necessary.
MR160008360,mass in left breast carcinoma breast.,biopsy from left breast.,received 3 grey white linear cores measuring 1 to 1.5cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as islands and nests. the neoplastic cells have moderate cytoplasm and exhibit moderate nuclear pleomorphism mitosis are discerned. the intervening stroma is fibrotic.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160008407,mass in left breast carcinoma breast.,biopsy from left breast mass.,received multiple grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue is processed.,linear cores of fibrocollagenous tissue harboring cellular lesion arranged as cords and sheets. the cells have irregular hyperchromatic nuclei inconspicuous nucleoli and moderate amount of cytoplasm. brisk mitotic activity noted.,features are consistent with high grade carcinoma. lobular suggest ihc.
MR160008431,complaint of left carcinoma breast.,a) breast lumpectomy wide excision.b) revised superior margin.c) revised deep margin.d) axillary lymph nodes.,a) received lumpectomy specimen measures 7x6x3cm.overlying skin ellipse measures 5x2.5cm with scar measures 3.8cm. cut surface shows grey white tumor measures 1.2x0.8x0.6cm. located at the following distances from the respective margins: superior margin 3cminferior margin 1.5cmmedial margin 1.5cmlateral margin 4cmdeep margin 0.7cmb) revised superior margin:received fibrofatty tissue measures 6x4x3cm. on surface is inked.c) revised deep margin:received fibrofatty tissue with muscle bundles measures 3.5x2.5x1cm. one surface is inked.d) axillary lymph nodes:received fibrofatty tissue measures 6x4x3cm. largest lymph node measures 1.2x0.8x0.7cm. cut surface shows grey yellow to grey white. dissected 16nodes.,a) breast lumpectomy wide excision:tumor bed: the section shows residual viable tumor present consisting of diffuse sheets of tumor arranged in isolated pattern. the cells consisting of pleomorphic nucleus with hyperchromatic nucleus in focal areas some ducts are showing ductal carcinoma in situ low grade. invasive ductal carcinoma with lobular features.grade mbr score tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9 nuclear grade iilymphovascular invasion is not present.perineural invasion is not present.resected margins: superior margin shows ductal carcinoma in situinferior margin free of tumormedial margin free of tumor.lateral margin free of tumordeep margin involved by tumor.b) revised superior margin:shows fibrofatty tissue with ducts epithelial hyperplasia free of tumor.c) revised deep margin:shows muscle bundles free of tumor.d) axillary lymph nodes:16 nodes no deposits of tumor.,a) breast lumpectomy wide excision:residual tumor present measures 1.2x0.8x0.6cm. invasive ductal carcinoma with lobular features with ductal carcinoma in situ present ( low grade).lymphovascular invasion is not present.perineural invasion is not present.resected margins inferior medial lateral margins are free of tumor.b) revised superior margin: free of tumor.c) revised deep margin: muscle bundle free of tumor.d) axillary lymph nodes: 16 nodes no deposits of tumor.
MR160008435,small retroareolar left breast lesion carcinoma.,biopsy from left breast.,received 6 linear cores measuring 0.7 to 1cm.entire tissue processed.,linear cores of breast parenchyma harboring occasional invasive cell clusters exhibiting moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. foci of solid high grade ductal carcinoma in situ seen.,small volume of invasive carcinoma biopsy from left breast.foci of high grade solid ductal carcinoma in situ seen.
MR160008436,mass in right breast carcinoma breast.,biopsy from right breast.,received 3 grey white to grey brown linear cores measuring 1 to 1.5cm.entire tissue processed.,linear cores of breast tissue with a neoplasm arranged as islands and sheets. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. lymphovascular emboli seen. the intervening stroma is fibrotic.,invasive ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160008495,left breast lump carcinoma.,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 1 to 1.5cm.entire tissue processed.,linear cores of breast tissue harboring neoplasm arranged as tubules cords and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is scant.,invasive carcinoma with lobular features biopsy from left breast.modified br score is 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures :1 6 9
MR160008554,left breast lump carcinoma.,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 0.4 to 1cm.entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as clusters. the neoplastic cells exhibit moderate nuclear pleomorphism hyperchromasia and have moderate cytoplasm. the intervening stroma is fibrotic. lymphovascular emboli seen.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160008559,mass in left breast carcinoma breast.,biopsy from left breast.,received 4 grey white linear cores measuring 0.7 to 1.4cm.entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasia arranged as islands and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic to vesicular nuclei prominent nucleoli and moderate cytoplasm. the stroma is fibrotic.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160008566,mass in right breast carcinoma breast.,biopsy from right breast mass.,received 3 grey white linear cores measuring 0.9 to 1.2cm.entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged as tubules nests and cords of pleomorphic cells with hyperchromatic pleomorphic nuclei few with prominent nucleoli and abundant amount of eosinophilic cytoplasm. mitotic figures discerned. lymphovascular invasion not identified.,biopsy from right breast mass :invasive ductal carcinoma grade 2.modified br score is 6 9 .tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR160008574,mass in right breast carcinoma breast.,biopsy from right breast.,received grey white to grey brown linear cores measuring 1 to 1.2cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as islands nests and sheets and cords. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic to vesicular nuclei conspicuous nucleoli and moderate cytoplasm.,infiltrated ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2.tubule formation :3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160008590,mass in right breast carcinoma breast.,biopsy from right breast lesion.,received multiple grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue is processed.,linear cores of breast parenchyma exhibiting a neoplastic lesion arranged in nests and acinar configuration consisting of oval to polygonal cells harboring hyperchromatic nuclei with marked nuclear pleomorphism and abundant pale eosinophilic cytoplasm. few bizarre giant cells and multinucleated cells are noted. intervening areas show fibrocollagenous stroma with mixed inflammatory infiltrate.,biopsy from right breast lesion:high grade carcinoma primary in breast metastatic from elsewheresuggest ihc.please correlate with clinical and radiologic findings.
MR160008623,mass in right breast carcinoma breast.,right breast mass.,received 4 grey white linear cores measuring 0.7 to 1cm.entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged as tubules and cords of cells with round to oval hyperchromatic pleomorphic nuclei and moderate cytoplasm. mitotic figures discerned. intervening stroma hows mild lymphocytic infiltrate.,right breast mass :invasive ductal carcinoma grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160008741,mass in left breast carcinoma breast.,biopsy from left breast.,received 4 grey white linear cores measuring 1 to 1.2cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as islands nests and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. foci of comedo ductal carcinoma in situ seen.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160008891,left breast lump carcinoma.,biopsy from left breast.,received 5 grey white to grey brown linear cores measuring 0.5 to 0.8cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as sheets nests and tubulkes. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is desmoplastic.,infiltrating ductal carcinoma biopsy left breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160008916,right breast lump carcinoma.,biopsy from right breast.,received 4 grey white to grey brown linear cores measuring 1 to 1.5cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords and trabeculae. the neoplastic cells exhibit moderate nuclear pleomorphism have relatively eccentrically placed nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,infiltrating carcinoma with lobular features biopsy right breast.modified br score is 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160008968,carcinoma left breast(previous lumpectomy margins status unknown),left modified radical mastectomy.,received in : formalinprocedure : modified radical mastectomy( post lumpectomy ) laterality : left total dimensions : medial lateral 12.5cm superficial deep 3cm superior inferior 12cmskin ellipse : 12x6cm nipple and areola : unremarkablesurgical defect : measures 4.5cm in length in outer quadranttumor : single grey white to grey brown lesiontumour size : 3x2.2x1.5cm location of tumor : deep to surgical scar 3 o clock position grey white areas margins of tumor : ill defined deep margin : 0.5cm muscle : present measures 2x2cm.adjacent breast : fibrosis seen axillary tail : 7x6x2cm.total number of nodes : 15 nodessize of largest node : 3.5x1.4x1cm cut surface shows grey white appearance.,sections reveal breast parenchyma demonstrating multiple foci of foreign body giant cell reaction collection of macrophages plasma cells lymphocytes and areas of fibrosis. adjacent breast parenchyma shows features of adenosis and apocrine change.,left breast left modified radical mastectomy: no residual tumor status post lumpectomy. in a diagnosed case of carcinoma breast no dcis seen lymphovascular invasion is not identifiedperineural invasion is not identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: 15 lymph nodes metastasis: 1(1 15) . summary: left modified radical mastectomy: no residual tumor status post lumpectomy.nodal metastases one of 15 lymph nodes shows metastatic tumor deposits.(1 15)no perinodal spread is seen..
MR160008969,left breast lump carcinoma.,biopsy from left breast lump.,received 6 greywhite to greyyellow linear cores measuring 0.6 to 0.8cm. entire tissue processed.,linear cores of breast parenchyma harboring cellular lesion arranged as nests and sheets. the cells have irregular hyperchromatic nucleus inconspicious nucleoli and moderate amount of cytoplasm. nuclear pleomorphism is marked. brisk mitotic activity noted.,invasive ductal carcinoma grade 3.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 dcis component is not seen.
MR160008976,mass in left breast carcinoma breast.,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 1 to 1.2cm.entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as islands and sheets. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is desmoplastic.,infiltrating ductal carcinoma biopsy left breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160009003,known case of carcinoma l.b post mrm (2years).,liver biopsy.,received multiple grey white fragmented measures 0.2 to 0.4cm. entire tissue processed.,section shows fibrocollagenous stroma shows an infiltration lesion arranged in sheets and nests. the cells are round to oval hyperchromatic nuclei abundant eosinophilic cytoplasm. atypical mitosis noted. adjacent lymphoplasmacytic infiltrates noted.,liver biopsy:metastatic carcinoma in known case of carcinoma breast.
MR160009008,carcinoma breast right.,a) wide excision lumpectomyb) sentinel lymph nodes.,a) received lumpectomy specimen measures 8x9x2.5cm. cut surface shows well circumscribed grey white tumor measures 1.8x1.5x1.5cm. located at the following distances from the respective margins: superior margin 3cminferior margin 4.5cmmedial margin 2.5cmlateral margin 4.5cmdeep margin 1cmb) sentinel lymph nodes:received fibrofatty tissue measures 3x2.5x1.5cm. largest lymph node measures 1x0.8x0.6cm. dissected 4 nodes.,a) wide excision lumpectomy:tumor bed: tumor is composed of clumps groups of pleomorphic nucleus and hyperchromatic nucleus and scanty cytoplasm.invasive ductal carcinomagrade: tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9 nuclear grade ii.ductal carcinoma in situ present (low grade) with solid type.lymphovascular invasion is not present.perineural invasion is not present.resected margins: medial margin free of tumorsuperior margin free of tumorinferior margin free of tumordeep margin free of tumorb) sentinel lymph nodes:4nodes no deposits of tumor.,a) wide excision lumpectomy:invasive ductal carcinoma.maximum dimension of the tumor is 1.8x1.5x1.5cmnuclear grade ii.ductal carcinoma in situ is present low grade with solid type.lymphovascular invasion is not present.perineural invasion is not present.all resected margins are free of tumor.b) sentinel lymph nodes:4 nodes show no deposits of tumor.pathological stage: pt1n0.
MR160009026,carcinoma left breast post ct.,a) wide local excision of left breast lump.b) revised inferior marginc) left axillary dissection.,a) received lumpectomy specimen measures 5.2x4x3.5cm. skin ellipse measures 2.5x0.5cm. cut surface shows illdefined grey white mucinous tumor measures 1.3x2.2x1.5cm. located at the following distances from the respective margins: superior margin 0.8cminferior margin 0.9cmmedial margin 1.2cmlateral margin 1.5cmdeep margin 0.7cmb) received fibrofatty tissue measures 4.4x3x1.5cm. one surface is inked.c) received fibrofatty tissue measures 7x5x3cm. largest lymph node measures 1.5x1x1cm. cut surface shows grey white appearance.,a) wide local excision of left breast lump:tumor bed: pools of mucin and tumor cells are present in the clumps and groups with pools of mucin.mucinous carcinomatubule formation 2nuclear pleomorphism 2mitotic figures 1 mbr score 5 9 ductal carcinoma in situ is not present.lymphovascular invasion is not present.perineural invasion is not present.resected margins superior margin free of tumorinferior margin shows epithelial hyperplasiamedial margin free of tumorlateral margin free of tumordeep margin free of tumorb) revised inferior margin: shows fibrofatty tissue free of tumor.c) left axillary dissection:15 nodes no deposits of tumor.,a) wide local excision of left breast lump:lumpectomy with axillary clearance.residual viable tumor presentmucinous carcinomamaximum dimension of residual tumor is 1.3x2.2x1.5cmnuclear grade iductal carcinoma in situ is not presentlymphovascular invasion is not present.perineural invasion is not presentresected margins superior medial lateral and deep margins free of tumor.b) revised inferior margin:free of tumor.c) left axillary dissection:15nodes no deposits of tumor.
MR160009028,mass in left breast carcinoma breast.,biopsy from left breast.,received 4 grey white linear cores measuring 1 to 1.2cm.entire tissue processed.,section shows breast parenchyma harboring a lesion arranged in cords nests and trabeculae showing round to oval cells with pleomorphic hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm .stroma shows fibrosis and areas of necrosis.,invasive ductal carcinoma grade 2.modified br score is 7 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160009052,known case of carcinoma breast.,biopsy from left supraclavicular node.,received 4 grey white linear cores measures 0.4 to 0.5cm. entire tissue processed.,section shows fragments of fibrocollagenous tissue infiltratied by neoplastic cells arranged in sheets and abortive tubules with focal areas of necrosis. the tumor cells round to irregular hyperchromatic nucleus moderate vacuolated cytoplasm.,biopsy from left supraclavicular node:metastatic carcinomatous deposit in a known case of carcinoma breast.
MR160009069,left breast lump carcinoma.,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 0.8 to 1cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as sheets and islands. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic to vesicular nuclei conspicuous nucleoli and moderate cytoplasm. foci of necrosis seen.,invasive ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 foci of necrosis seen.
MR160009111,mass in left breast carcinoma breast.,biopsy from left breast mass.,received multiple grey white to grey brown linear cores measures 1.2 to 1.5cm. entire tissue is processed,linear cores of tissue exhibiting cellular proliferation of large round to oval cells with eccentrically placed hyperchromatic nuclei and abundant pale eosinophilic to clear cytoplasm and brisk mitotic activity.,biopsy from left breast lesion:suggestive of invasive lobular carcinoma (signet ring cell type)tubule formation 3nuclear pleomorphism 2mitotic activity 3 score 8 9 nuclear grade iiiplease rule out a remote possibility of this being metastatic from stomach.suggest ihc.
MR160009114,case of left carcinoma breast.,left modified radical mastectomy.,received in : formalinprocedure : modified radical mastectomy laterality : left total dimensions : medial lateral 20cm superficial deep 4cm superior inferior 16cmskin ellipse : 13x9.5cm nipple and areola : shows surface ulcerationscar surgical defect : not seentumor : single tumour size : 3x2.5x2cm location of tumor : central quadrant above nipple and areolamargins of tumor : illdefined deep margin : 2cm muscle : absent adjacent breast : fibrofatty tissue axillary tail : 6x5x2cmtotal number of nodes : 20 nodessize of largest node : 2x1x1cm cut surface shows grey white,multiple sections from the breast parenchyma show a neoplastic lesion infiltrating the stroma. cellsexhibit moderate nuclear pleomorphism vesicular nuclei prominent nucleoli and moderate eosinophilic cytoplasm. mitotic figures are discerned. ductal carcinoma in situ is noted of cribriform and solid type. lymphovascular invasion not identified. perineural invasion is not identified. areas of fibrosis show ducts with cystic dilatation adenosis and apocrine change seen.,left breast left modified radical mastectomy: invasive ductal carcinoma grade ii. modified br score is 6 9.tubule formation: 2nuclear pleomorphism: 2mitotic figures: 2tumor measures 3x2.5cm in greatest dimension and is located in the central quadrant. ductal carcinoma in situ is present with cribriform and solid type. lymphovascular invasion is identified.perineural invasion is not identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: 1 lymph node shows metastatic deposits of tumor out of 26 nodes.(1 26)pathological stage : pt2n1.summary:left mrm invasive ductal carcinoma grade ii. nodal metastases 1 lymph node shows deposits of tumor out of 26 nodes.perinodal spread is not present.
MR160009115,case of lump in left breastsuggestive of carcinoma left breast.,biopsy from left breast mass.,received 3 grey white to grey brown linear cores measuring 0.8 to 1.2 cm. entire tissue is processed.,sections show multiple linear cores of breast parenchyma demonstrating neoplastic lesion arranged in nests sheets and tubules. tumor cells exhibit moderate nuclear pleomorphism with hyperchromatic nuclei and abundant eosinophilic cytoplasm.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160009181,right breast mass carcinoma breast.,right breast mass biopsy.,received 4 grey white to grey brown linear cores measuring 0.8 to 1cm.entire tissue processed,section shows cores of breast tissue focally infiltrated by a lesion arranged in cords with pleomorphic hyperchromatic nuclei with irregular border inconspicuous nucleoli and scanty cytoplasm. adjacent stroma shows fibrosis and hyalinisation along with extensive areas of necrosis.,right breast mass biopsy :small volume of invasive ductal carcinoma grade 2.modified br score is 6 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 areas of necrosis seen.
MR160009202,left lung mass.carcinoma breast.,biopsy from left lung lesion.,received multiple grey white to grey black linear cores measures 0.5 to 0.8cm. entire tissue is processed.,fragmented linear cores of necrotic tissue demonstrating few tiny small scattered islands of round to oval neoplastic cells with hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm.,biopsy from left lung lesion : known case of carcinoma breast.tiny foci of pleomorphic tumor cells secondaryihc may be attempted.
MR160009204,solid cystic left breast mass carcinoma breast.,biopsy from left breast.,received five grey white to grey brown linear cores measuring 0.4 to 0.8cm.entire tissue processed.,linear cores of breast parenchyma harboring a neoplasm arranged along fibrovascular cores in papillary pattern and as islands. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. lymphvascular emboli seen.,invasive carcinoma favoring invasive ductal carcinoma with papillary pattern biopsy from left breast.modified br score 5 9 grade 1.tubule formation : 3nuclear pleomorphism : 1mitotic figures :1 5 9
MR160009252,lump in right breast carcinoma right breast.,right breast core biopsy.,received 3 grey white to grey brown linear cores measuring 0.6 to 1.5 cm.,linear cores of tissue from breast parenchyma shows a neoplastic lesion arranged in tubules nests and cords. the individual cells show moderate nuclear pleomorphism with hyperchromatic nuclei and eosinophilic cytoplasm. adjacent stroma shows elastosis and necrosis.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160009303,complaint of lump in right breast .suggestive of carcinoma right breast.,biopsy from right breast mass.,received 2 grey white linear cores measuring 0.7 to 0.9 cm.entire tissue processed.,section shows cores of breast parenchyma harboring a lesion arranged in cords nests trabeculae comprising of pleomorphic cells with normal to oval hyperchromatic nuclei inconspicious nucleoli and modearte amount of eosinophilic cytoplasm. stroma shows hyalineration and fibrosis .focus with ductal carcinoma in situ with solid and cribriform pattern are seen.foci of necrosis seen.,right breast mass biopsy.invasive ductal carcinoma grade 2modifies br score 3+2+2 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 ductal carcinoma in situ with should and cribriform pattern seen.
MR160009331,consisting of lump in right breast mammogram and usg suggestive of carcinoma right breast,biopsy from right breast mass.,received 5 grey white linear cores measuring 0.7 to 1 c.mentire tissue processed.,section shows multiple linear cores of breast parenchyma demonstrating a neoplastic lesion arranged in tubules cords and in sheets. tumor cells exhibit moderate nuclear pleomorphism with hyperchromatic nuclei and abundant eosinophilic cytoplasm.,right breast biopsy :invasive ductal carcinoma grade 2. modified bloom richarandson score is 6(3+2+1).
MR160009335,complaint of lump in right breast carcinoma right breast.,biopsy from right breast mass.,received 5 grey white linear cores measuring 0.5 to 0.7 cm.entire tissue processed.,section shows linear cores of breast tissue infiltared by a lesion arranged in tubules nests cords trabeculae and sheets .cells have round to oval moderately pleomorphic hyperchromatic nuclei and moderate to abundant cytoplasm. few show prominent nucleoli. mitotic figures discerned. adjacent stroma shows fibrosis and hyalinisation.,right breast trucut biopsy.invasive ductal carcinoma grade ii.modified br score ( 6 9).tubule formation 2nuclear pleomorphism 2mitotic figures 2 6
MR160009345,case of right breast lump mammogram and usg : carcinoma right breast.,usg guided trucut needle biopsy from right breast mass.,received 3 greyyellow linear cores measuring 1 to 1.2cm. entire tissue is processed.,sections show linear cores of breast parenchyma demonstrating a neoplastic lesion arranged in nests sheets and tubules . individual cells show moderate nuclear pleomorphism with hyperchromatic nuclei and abundant eosinophilic cytoplasm. adjacent stroma shows desmoplasia fibrosis and hyalinisation.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160009346,a) b) case of lumps in both breasts.mammogram carcinoma both breasts.,a) biopsy from right breast mass.b) biopsy from left breast mass.,a) received multiple grey white to grey brown linear cores measures 0.7 to 1.2cm. entire tissue is processed.b) received multiple grey white linear cores measures 0.6 to 1.2cm. entire tissue is processed.,a) section shows linear cores of breast parenchyma showing invasive sheets nests of dysplastic ductal cells showing moderate pleomorphism hyper chromatic nuclei and moderate amount of cytoplasm. at few foci the cells are arranged in india file pattern showing pseudo tracking. the stroma is desmoplastic. mitotic activity is discernable.b) section showing linear cores of breast tissue composed of neoplastic lesion consisting of invasive nests and sheets of dysplastic cells showing moderate pleomorphism and hyperchromatic nuclei. few foci showing mucin pools. the intervening stroma shows desmoplasia and few cystically dilated glands.,a) invasive ductal carcinoma with lobular differentiation (invasive carcinoma nos) with grade ii.mbr score 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9 b) invasive carcinoma nos grade i.(invasive ductal carcinoma with mucinous areas)mbr score 5 9tubule formation 2nuclear pleomorphism 2mitotic figures 1 5 9
MR160009358,right breast mass carcinoma breast,biopsy from right breast mass..,received 4 grey white linear cores measuring 0.7 to 1 cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by neoplasm arranged as cords and trabeculae. the neoplastic cells have hyperchromatic nuclei eccentrically placed and moderate cytoplasm. the intervening stroma is elastotic.,invasive carcinoma with lobular features biopsy right breast.grade 1 (5 9) tubule formation 3nuclear pleomorphism 1mitotic figures 1 5
MR160009359,carcinoma left breast.,left breast left modified radical mastectomy.,received in : formalin.procedure : modified radical mastectomylaterality : lefttotal dimensions : medial to lateral : 22cm. superficial to deep : 3cm. superior to inferior :20cm.skin ellipse : 17 x 9.5 cm. nipple amp areola : unremarkable. scar surgical defect : not seentumor : singletumour size : 3 x 2.5 x 2 cm. location of tumor : upper outer quadrant margins of tumor : illdefined. deep margin : 0.4cm.adjacent breast : fibrofatty tissue axillary tail :7 x 6 x 2 cm.size of largest node :1.8 x 1.5 x 1 cm. cut surface grey white.representative sections are submitted.,section shows breast parenchyma harboring a lesion arranged in nests cords trabeculae and sheets . individual tumour cells have round to oval pleomorphic vesicular nuclei prominent nucleoli and moderate amount of eosinophilic cytoplasm. areas of necrosis seen. stroma shows extensive hyalinisation and fibrosis. lymphovascular invasion is identified. perineural invasion is not identified.,left breast left modified radical mastectomy : invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2). tumour is unifocal and is located in the upper outer quadrant. tumor measures 3 cm in greatest dimension. lymphovascular invasion is identified. perineural invasion is not identified. ductal carcinoma in stu of solid and cribriform pattern with intermediate nuclear grade. posterior resection margin is free of tumor and is 0.4 cm away from the tumour. nipple and areola are free of tumor.lymph nodes: two out of seventeen lymph nodes show metastatic tumour deposits(2 17). size of the larger tumour deposit measures 0.6 cm in greatest dimension. no extranodal extension is seen.pathological stage : pt2n1asummary : left mrm invasive ductal carcinoma grade 2.nodal metastases two out of seventeen lymph nodes show metastatic deposits of tumor (2 17).
MR160009364,mass in left breast carcinoma breast.,biopsy from left breast mass.,received multiple grey white to grey brown linear cores measures 1 to 1.3cm. entire tissue is processed.,linear cores of breast parenchyma exhibiting a neoplastic lesion arranged in sheets and nests consisting of round to oval cells demonstrating moderate nuclear pleomorphism and abundant eosinophilic cytoplasm amidst a desmoplastic stroma with scattered lymphocytic infiltrate.,biopsy from left breast lesion:invasive carcinoma grade ii.tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR160009372,mass in left breast carcinoma breast.,left breast mass biopsy.,received 3 grey white linear cores measuring 0.7 to 0.8cm.entire tissue processed.,section shows tumor cells in tubules nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass biopsy :invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR160009380,carcinoma right breastright supraclavicular lymph node metastatic,biopsy from right supraclavicular lymph node.,received 4 grey white linear cores measures 0.8 to 1 cm. entire tissue processed.,sections from cores of lymph node shows metastatic tumor deposits of cells in diffuse sheets nests and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right supraclavicular lymph node(in a known case of carcinoma right breast) :suggestive of metastatic invasive ductal carcinoma in known case of carcinoma breast.
MR160009385,mass in left breast carcinoma breast,biopsy from left breast mass,received 4 grey white linear cores measures 1 to1.2cm. entire tissue processed.,linear cores of tissue demonstrating sheets and fascicles of spindle cells with plump ovoid nuclei and moderate amount of eosinophilic cytoplasm. foci of cells show moderate nuclear pleomorphism. mitotic figures are discerned. there are interspersed vascular channels. no necrosis is identified.,biopsy from left breast mass:spindle cell neoplasmsuggestive of phyllodes tumor borderline.suggest further confirmation on excision specimen.
MR160009492,mass in right breast carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measures 1 to1.5 cm. entire tissue processed.,section shows cores of tissue infiltrating by tumor cells in diffuse sheets and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ducal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR160009519,left breast lump carcinoma left axillary nodes.,biopsy from left breast lump.,received 4 greywhite to greybrown linear cores measuring 1 to 1.4 cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a lesion comprising of atypical cells with markedly pleomorphic large round to oval vesicular to hyperchromatic nuclei prominent nucleoli and moderate amount of pale granular eosinophilic cytoplasm with irregular borders. mitotic figures discerned. ductal carcinoma in situ noted with comedonecrosis. adjacent stroma shows fibrosis and inflammatory infiltrate.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR160009522,known case of carcinoma left breast post op mrm with lymphodema left upper limb with angiosarcoma.,incisional biopsy from nodule on left fore arm.,received one nodular grey white mass measures 0.9x0.8x0.7cm cut surface shows grey whiteto grey brown. distance from nearest ink margin is 0.2cm.,section showing stratified squamous epithelium with subepithelium showing a lesion arranged inlobules. in lobules vessels varying size lined by elongated cells with scant cytoplasm and prominentnucleoli is seen. surrounding subepithelial stroma showing granulation tissue and inflammatory infiltrate composed of lymphocytes macrophages and plasma cells.,incisional biopsy from nodule on left fore arm:suggestive of vascular lesion epitheloid angiosarcoma.suggest ihc for further confirmation.
MR160009554,mass in right breast carcinoma breast,biopsy from right breast mass.,received 4 grey white to grey brown linear cores measuring 0.8 to 1 cm.,section from right breast mass shows cells arranged in clusters. the cells are small show round nucleus small nucleoli and scanty cytoplasm. areas of extracellular mucin noted. necrosis seen.,invasive carcinoma ( with extracellular mucinous component) grade 6 9 grade ii.tubular formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR160009574,multiple liver space occupying lesion metastases,biopsy from liver lesion.,received multiple grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue is processed.,linear cores of tissue demonstrating proliferation of round cells in sheets cords and trabecular configuration harboring hyperchromatic nuclei inconspicuous nucleoli and moderate amount of pale staining cytoplasm. adjacent areas show sparsely cellular fibrovascular stroma.,biopsy from liver lesion:poorly differentiated malignancy. metastatic carcinoma from breast. metastatic neuroendocrine tumor.suggest ihc.
MR160009611,left breast mass. carcinoma breast,biopsy from left breast,received from 5 grey white to grey brown liner core measuring 1.2 to 1.5 cm. entire tissue processed.,section shows cores breast parenchyma showing normal ductal cells with liner epithelial and outer myoepithelial cells. stroma shows abundant inflammatory cells consisting of lymphocytes neutrophils plasma cells admixed with epithelial cells and histiocytes. stroma shows hyalinization and fibrosis.,left breast biopsy :features are suggestive of chronic non specific mastitis.no evidence for malignancy.
MR160009612,case of right breast paget s,right breast nipple excision,received nipple and areola with attached fibrofatty tissue total measures 4x3.2x2cm. nipple is hypopigmented and shows grey brown areas and ulceration.,the epidermis of the nipple and areola is replaced by oval to polyhedral cells with hyperchromatic nucleus and vacuolated cytoplasm. in the subepithelium breast parenchyma shows ductal carcinoma in situ solid type low grade. in all focal area small clumps of invasive ductal carcinoma is present consisting of 3 4 pleomorphic cells surrounding with lymphocytes. resected inked margins are 0.5cm away from the tumor.,right nipple excision :paget s disease parenchyma shows ductal carcinoma in situ solid type and small focus of invasive ductal carcinoma is present.resected inked margins are 0.5cm away from the tumor.
MR160009615,case of left breast lump.,a) left breast lumpectomy.b) left axillary lymph node dissection specimen.,a) received lumpectomy specimen measuring 6.5x6x2.5cm. skin ellipse measuring 3.5x1.3cm.cut surface grey white mass measuring 1.8x1.7x1.2cm.distance from margins :superior : 1.5cm.inferior : 2cm.medial : 1.3cm.lateral : 1.5cm.deep : 0.8cm.b) received fibrofatty tissue measuring 11x7x3cm. largest lymph node measuring 1.5x1x1cm. cut surface fatty infiltration.,a) sections from tumor show breast parenchyma infiltrated by a neoplasm arranged as islands and nests. the neoplastic cells have vesicular nuclei conspicuous nucleoli exhibiting nuclear pleomorphism and have moderate cytoplasm. no perineural invasion seen. no lymphovascular emboli seen. foci of high grade ductal carcinoma in situ (solid pattern)noted.b)18 lymph nodes isolated are free of tumor.,a) invasive ductal carcinoma left breast.tumor size : 1.8x1.7x1.2cm.foci of ductal carcinoma in situ (high grade ) seen.no lymphovascular invasion seen.no perineural invasion seen.all resected margins including deep are free of tumor.b) 18 left axillary lymph nodes isolated are free of tumor.
MR160009652,carcinoma right breast post lumpectomy.,right breast right modified radical mastectomy post lumpectomy.,procedure : modified radical mastectomy post lumpectomy. laterality : righttotal dimensions : medial to lateral : 16cm. superficial to deep : 6cm. superior to inferior : 15cm.skin ellipse : 12x9cm. nipple areala unremarkable :normal surgical defect above n a measuring 4cm in length .tumor grey white to grey yellow illdefined lesion with fibrotic areas.tumour size : 2.8x2x2cm. location of tumor : central (retroscar area ).margins of tumor : illdefined. deep margin : 0.5muscle : present measuring 4x3cm.adjacent breast : fibrofatty tissue.axillary tail : 6x5x2.5cm.largest lymph node measuring 2x1.8x1.2cm. cut surface grey white.total lymph nodes 14.,multiple sections from the lesion shows breast parenchyma harboring an infiltrating ill defined lesion arranged in indian file and targetoid patter. the cells are ovoid having moderate to scanty amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma shows extensive areas of desmoplasia with chronic inflammatory infiltrates. areas of hemorrhage and necrosis noted. lymphovascular emboli noted.,right breast right mrm post lumpectomyresidual invasive lobular carcinoma grade 2. status post lumpectomy.modified br score (3+2+2 7 9)tumor measures 2 8 cm in greatest dimension and is located in the central quadrant.lobular carcinoma in situ seenlymphovascular invasion identified.perineural invasion indeterminateposterior resection margin is free of tumor.nipple areola is free of tumor.lymph nodes: isolated 14 lymph nodes one shows metastatic tumor deposit (2 14)largest tumor foci measures 0.4cm.extra nodal extension is not seen.summary: right mrm residual lobular carcinoma post lumpectomy grade ii.lymph nodes: isolated 14 lymph nodes one shows metastatic tumor deposit (2 14)
MR160009657,right breast mass carcinoma breast,biopsy from right breast.,received 3 grey white to grey brown linear cores measures 1 to 1.2 cm. entire tissue processed.,section shows arranged in nests cords and sheets. individual cells have moderate cytoplasm and hyperchromatic nuclei. necrotic areas are seen.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6 (3+2+1)
MR160009683,right breast mass.carcinoma breast.,biopsy from right breast.,received multiple grey white to grey brown linear cores measures 0.5 to 1cm. entire tissue is processed,linear cores of cellular lesion arranged as sheets. the cells have vesicular to hyperchromatic nucleus few showing prominent nucleus and moderate amount of cytoplasm. multinucleated tumor giant cells are seen. mitotic figures are discerned including atypical forms.,invasive ductal carcinoma grade iii.tubule formation 3nuclear pleomorphism 3mitotic figures 2 8 9
MR160009760,left breast mass carcinoma breast.,biopsy from left breast mass.,received 7 greywhite to greybrown linear cores measuring 1.2 to 1.5cm. entire tissue processed.,section shows tumor arranged in nest sheets and cords. the cells are round to oval with moderate to abundant cytoplasm and hyperchromatic nuclei. adjacent stroma showing lymphocytic infiltrate. areas of hemorrhage seen.,left breast biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160009786,left breast lump carcinoma.,biopsy from left breast lump.,received 4 greywhite linear cores measuring 1.2 to 1.5 cm. entire tissue processed.,linear cores from breast shows proliferating tubules and ducts lined by columnar cells with moderate cytoplasm and round to oval nuclei. few ducts are cystically dilated showing secretory changes. adjacent stroma showing lymphocytic infiltrate. no evidence of malignancy seen.,left breast biopsy :features are suggestive of proliferative breast disease with adenosis.no evidence of malignancy in the section studied.
MR160009822,left breast mass carcinoma breast.,biopsy from left breast lesion,received multiple grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue is processed.,linear cores of tissue exhibiting a neoplastic lesion arranged in sheets nests and vague tubular configuration demonstrating moderate nuclear pleomorphism and eosinophilic cytoplasm amidst desmoplastic stroma and dense lymphoplasmacytic infiltrate. atypical mitotic figures are discerned.,biopsy from left breast lesion:invasive ductal carcinoma grade iitubule formation 2nuclear pleomorphism 2mitotic figures 3 mbr score 7 9
MR160009823,left breast lump cancer,biopsy from left breast lump.,received 3 grey white to grey brown linear cores measuring 1.2 to 1.3 cm,section shows multiple linear cores of breast parenchyma with an infiltrating neoplastic lesion arranged in tubules corde and nests. the cells are ovoid cells having moderate amount of cytoplasm hyperchromatic pleomorphic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows dismoplasia with inflammatory infiltrates. ductal carcinoma in situ is noted. area of hemorrhage and necrosis seen.,left breast lump biopsy:invasive ductal carcinoma grade 2mbr score (2+2+3 7 9)tubular formation 2nuclear pleomorphism 2mitosis 3 7 ductal carcinoma in situ cribriform and solid pattern noted.
MR160009852,right breast lump carcinoma breast,biopsy from right breast,received 3 grey white linear cores measuring 1 to 1.2 cm.entire tissue processed.,section shows cores of breast parenchyma harboring an infiltrative lesion arranged in nests cords and lobules. cells exhibit moderate to marked nuclear pleomorphism high n c ratio hyperchromatic nuclei and moderate eosinophilic cytoplasm. stroma shows dense lymphoplasmocytic infiltrate.,right breast:invasive ductal carcinoma grade iimodified br score (7 9)tubular formation 2nuclear pleomorphism 3mitotic figures 2 7 9
MR160009864,right axillary and supraclavicular lymphnode.,biopsy from right axillary node.,received 4 grey white linear cores measuring 0.8 to 0.9 cm.entire tissue processed.,section from right axillary lymphnode shows sheets and cluster of neoplastic cells showing round vesicular nucleus with conspicuous nucleoli and eosinophilic cytoplasm.,metastatic carcinomaplease look for primary in breast lung.
MR160009867,carcinoma breast.,biopsy from subcutaneous nodule on back.,received single globular fibrofatty tissue measures 2.4x2.2x1cm.,section demonstrates a fibrofatty tissue infiltrated by neoplastic glands and nests consisting of cuboidal to oval cells exhibiting moderate to marked nuclear pleomorphism and eosinophilic cytoplasm amidst a desmoplastic stroma.,excision biopsy of subcutaneous nodule on back :metastatic carcinomatous deposits in a known case of carcinoma breast.tumor reaches till the inked resected marginsno lymphovascular invasion and perineural invasion identified.
MR160009872,left breast mass carcinoma,biopsy from left breast.,received 5 grey white to grey brown linear cores measures 0.6 to 0.8 cm. entire tissue processed.,linear cores show tumor arranged in sheets cords and nests. the cells have moderate to abundant cytoplasm with vesicular nuclei and prominent nucleoli. adjacent stroma shows mild lymphocytic infiltrate.,left breast core biopsy :invasive ductal carcinoma grade 3. modified bloom richardson score is 8 (3+3+2)
MR160009891,multiple irregular hypoeloic lesion in right breast carcinoma,biopsy from right breast,received 3 grey white to grey brown linear cores measured 1 to 1.1 cm.entire tissue processed.,linear cores shows a neoplastic lesion arranged in nest and cords having round to oval cells with moderate cytoplasm and hyperchromatic nuclei. there is moderate nuclear pleomorphism .adjacent stroma is myxoid.,right breast biopsy:invasive ductal carcinoma.grade 2 modified br score 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6
MR160009895,mass in left breast carcinoma breast.,biopsy from left breast mass.,received multiple grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue is processed.,section shows tumor arranged in cords trabecular cribriform and lobular pattern having round to polygonal cells with moderate cytoplasm and having hyperchromatic nuclei. focal lymphocytic infiltrate seen.,left breast biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160009983,right breast lump carcinoma,biopsy from right breast.,received multiple grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue is processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as islands and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,invasive ductal carcinoma biopsy from right breast:grade 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR160010044,known case of carcinoma anorectumpresented with breast lump hypoechoic irregular solid lesion in 12 o clock position of left breast.another thick walled cystic lesion in 1 2 o clock position of left breast.,biopsy of left breast lesion.,received multiple grey white to grey brown linear cores measures 0.8 to 1.5cm. entire tissue is processed,linear cores of tissue infiltrated by nests cords islands of round to oval neoplastic cells demonstrating moderate nuclear pleomorphism eosinophilic cytoplasm amidst a desmoplastic stroma.,biopsy from left breast lesion:invasive carcinoma suggestive of primary in breast.suggest ihc.
MR160010045,left breast mass carcinoma breast,biopsy from left breast,received 4 grey white to grey brown linear cores measuring 1 to 1.4cmentire tissue processed.,linear cores from breast shows neoplastic lesion arranged in cords and nests consisting of round to oval cells with abundant cytoplasm and hyperchromatic nuclei. there is nuclei to moderate nuclear pleomorphism. the intervening stroma is dismoplastic.,left breast biopsy:invasive ductal carcinomagrade 2 modified br score 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6
MR160010048,left breast lump carcinoma,biopsy from left breast lump.,received 4 grey white linear cores measuring 0.5 to 0.7 cmentire tissue processed.,linear cores shows a neoplastic lesion arranged in sheets and cords. the cells are round to oval with moderate amount of cytoplasm and hyperchromatic nuclei. there is moderate amount of nuclear pleomorphism. adjacent stroma showing area of necrosis.,left breast lump biopsy:invasive ductal carcinomagrade 2 modified br score 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR160010056,large left breast lump carcinoma,biopsy from left breast lump.,received 5 grey white linear cores measuring 0.7 to 1 cmentire tissue processed.,linear cores of tissue exhibiting a neoplastic lesion arranged in cords and sheets consisting of round to oval cells demonstrating moderate nuclear pleomorphism and eosinophilic cytoplasm amidst a desmoplastic stroma.,left breast lump biopsy:invasive carcinoma with lobular featuresgrade 2 modified br score 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 crush artefact seen
MR160010060,left breast lump carcinoma,biopsy from left breast lump.,received 4 grey white linear cores measurimg 0.7 to 1 cmentire tissue processed.,linear cores of breast shows a neoplastic lesion arranged in cords and files. the cells are round to oval with scant to moderate amount of cytoplasm and hyperchromatic nuclei with mild nuclear pleomorphism. adjacent stroma showing desmoplastic changes.,left breast lump biopsy:invasive carcinoma with lobular featuresgrade 2 modified br score 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6
MR160010076,left breast masscarcinoma breast,biopsy from right breast lesion,received 4 grey white to grey brown linear cores measuring 0.7 to 1.2 cmentire tissue is processed.,linear cores of tissue infiltrated by nests sheet and vague tubular configuration of oval to round neoplastic cells with vesicular nuclei moderate nuclear pleomorphism and eosinophilic cytoplasm. there is brisk mitotic activity.,biopsy from right breast lesion:invasive carcinoma grade ii tubule formation 2nuclear pleomorphism 2mitotic figures 3 mbr score 7 9
MR160010078,solid cystic mass in left breast carcinoma,biopsy from left breast.,received 7 fragmented linear cores measuring 0.2 to 0.4 cm. entire tissue processed.,section shows fragments of breast parenchyma harboring a lesion arranged in papillary and tubular pattern few showing fibrovascular cores. individual cells are columnar with nuclear stratification vesicular nuclei inconspicuous nucleoli and moderate eosinophilic cytoplasm. stroma shows lymphoplasmacytic infiltration.,left breast core biopsy :suggestive of papillary lesion.suggest excision of the lump for further confirmation.
MR160010122,carcinoma left breast.,a) sentinel lymph node from axillab) wide excision of left breast lump.,a) received fibrofatty tissue measures 6x3x1cm. largest lymph node measure 1x1x0.8cm. cut surface shows fatty infiltration. dissected 5 lymph nodes.b) received lumpectomy specimen measures 5x4x2.8cm. cut surface shows grey white lesion measures 1.5x1x0.8cm. located at the following distance from the respective margins: superior margin 1.2cminferior margin 1.4cmmedial margin 0.5cmlateral margin 3cmdeep margin 0.9cm,a) sentinel lymph node from axilla:5 lymph nodes no deposits of tumor.b) wide excision of left breast lump:multiple sections from the mass show ducts are compressed with slit like spaces lined with flattened cuboidal epithelial cells with outer myoepithelial cells. the stroma is compact and cellular. there is no atypical hyperplasia or no malignancy. all resected margins shows fibrofatty tissue.,a) sentinel lymph node from axilla:5 nodes no deposits of tumor.b) wide excision of left breast lump:fibroadenoma.no evidence of malignancy.
MR160010185,right breast lump,biopsy from breast lump,received 4 grey white to grey brown linear cores measuring 1 to 1.2 cm.entire tissue processed.,sections from multiple biopsy bits shows breast parenchyma harboring a neoplastic lesion arranged in nests sheets and acini floating in extensive pools of amphophilic mucin. cells show moderate amount of eosinophilic cytoplasm hyperchromatic nuclei with minimal pleomorphism regular nuclear borders. connective tissue bodies are seen surrounding the tumor cells.,biopsy from right breast lump:mucinous carcinoma nuclear grade i.
MR160010205,right breast lump carcinoma,biopsy from right breast lump,received 4 grey white linear cores measuring 0.6 to 1.2 cm.entire tissue processed.,section from multiple biopsy bits shows breast parechyma harboring a neoplastic lesion arranged in cords tubules and papillary pattern. cells have scant to moderate eosinophilic cytoplasm pleomorphic hyperchromatic nuclei and few cells show prominent nucleoli. mitotic figures of 4 5 10 hpf. areas of necrosis seen.,core biopsy right breast lump:invasive carcinoma grade 2 (3+3+1) modified br score 7 9tubule formation 3nuclear pleomorphism 3mitotic figures 1 7 9 areas of necrosis seen.
MR160010213,known case of carcinoma right breast post operative stomachright breast nodule adjacent to scar recurrence,biopsy from right breast nodule.,received 4 grey white linear cores measures 1 to 1.5 cm.entire tissue is processed.,section shows cores of tissue infiltrated by tumour cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast nodule core biopsy (post op case of carcinoma right breast) :suggestive of recurrence of invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR160010233,birads iv lesion in right breast,biopsy from right breast lesion.,received 3 grey white to grey brown linear cores measuring 0.5 to 0.8 cm.entire tissue processed.,linear trucut cores of breast parenchyma showing dilated ducts with ductal carcinoma in situ solid and cribriform type. foci of invasion noted with cells arranged as tubules cords and nests. cells display moderate pleomorphism hyperchromatic nuclei and inconspicuous nucleoli. stroma shows desmoplastic response.,invasive ductal carcinoma nos grade iitubular formation 3nuclear pleomorohism 2mitotic figures 1 6 9 ductal carcinoma in situ solid and cribriform type identified.
MR160010239,solid cystic mass in left breast carcinoma breast,biopsy from left breast lesion.,received multiple fragmented linear cores measuring 0.2 to 0.3 cm.entire tissue processed.,fragmented linear cores of tissue exhibiting proliferation of cuboidal to columnar cells in vague papillary and cribriform configuration demonstrating moderate atypia. mitotic figures are discerned. there are foci of necrosis.,biopsy from left breast lesion: papillary neoplasm ductal carcinoma in situ.
MR160010265,case of lump in left breast carcinoma left breast.,biopsy from left breast.,received 3 grey white to grey yellow linear cores measuring 0.6 to 1 cm.entire tissue processed.,linear trucut cores infiltrated by sheets cords clusters and occasional tubules of pleomorphic cells with round to oval nuclei dispersed chromatin and inconspicuous nucleoli. mitotic figures are discerned. foci of necrosis noted.perineural invasion seen however lymphovascular invasion is not identified. stroma shows desmoplasia.,left breast:invasive ductal carcinoma nos grade ii tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR160010266,case of lump in left breast carcinoma left breast,biopsy from left breast lesion.,received 4 grey white to grey brown linear cores measuring 0.3 to 0.6 cm.entire tissue processed.,multiple tiny fragmented linear cores of tissue demonstrating papillary like and glandular proliferation of cuboidal cells harboring vesicular nuclei and moderate amount of pale eosinophilic cytoplasm. intervening areas show vascularized fibrocollageous stroma and aggregates of foamy macrophages.,biopsy from left breast lesion: papillary neoplasm
MR160010280,case of lump in right breast carcinoma right breast,biopsy from right breast,received 4 grey white to grey brown linear cores measuring 0.8 to 1 cm. entire tissue processed.,section shows breast parenchyma infiltrated by a lesion arranged predominantly in cribriform pattern nests and cords. individual cells have round to oval hyperchromatic nuclei inconspicuous nucleoli and abundant clear to vacuolated cytoplasm. pools of extracellular mucin noted. areas of hemorrhage seen along with areas of fibrosis.,right breast biopsy biopsy:invasive carcinoma grade 2.possibilities are cribriform differentiation. adenoid cystic carcinoma.suggest ihc for further confirmation.
MR160010282,carcinoma left breast,a) right breast lump wide local excisionb) left breast lump breast conservative surgeryc) lymph node left axillary lymph node dissection,b) received lumpectomy specimen measures 7x6.5x2.5cm. cut surface shows a lesion measures 2.5x2.5x2cm.located at the following distances from the respective margins: superior margin 1.5cminferior margin 2cmmedial margin 2cmlateral margin 1cmdeep margin 0.8cma) received fibrofatty tissue measures 6x4x1.5cm. serial sectioning shows tiny illdefined grey white areas each measures 0.5x0.5cm. closest distance from inked margin is 0.1cmc) received fibrofatty tissue measures 6x5x3cm. largest lymph node measures 3.3x2.5x2cm.cut surface shows cystic necrotic grey white appearance.,b) section shows breast parenchyma harboring a neoplastic lesion arranged in sheets and tubules. individual cells have round to oval pleomorphic vesicular nuclei prominent nucleoli and moderate amount of cytoplasm. solid stroma shows desmoplama hyalinisation with inflammatory cells consisting of neutrophils and lymphocytes. solid ductal carcinoma in situ component is identified. perineural invasion is identified.a) section shows dilated ducts with a lesion arranged in papillary fronds with fibrovascular core. individual cells have round to oval bland nuclei and moderate amount of cytoplasm. adjacent breast show ductal hyperplasia and inflammatory cells consisting of lymphocytes.,b) left breast lump breast conservative surgery:invasive ductal carcinoma grade ii.mbr score is (3+2+1) 6tubule formation 3nuclear pleomorphism 2mitotic figures 1perineural invasion is identifiedlymphovascular invasion is indeterminateresected margins are free of tumorc) lymph node left axillary lymph node dissection:3 out of 7 lymph nodes isolated show metastatic deposits measuring 1.4cm in the greatest dimension.(3 7)a) right breast lump wide local excision:papillary lesion with foci of adneosis.closest ink margin is free of tumor. background shows ductal hyperplasia amidst the fibrotic stroma. report on ihc to follow.case discussed with colleagues
MR160010284,carcinoma breast,a) left axillary sentinel nodes.b) left breast lump wide excision,a) received 2 fibrofatty tissue measures 5x4x2cm. largest lymph nodes measures 1.4x1x0.8cm. cut surface shows grey whiteb) received lumpectomy specimen measures 7x6x2cm. skin ellipse measures 1x0.8cm. cut surface shows grey white lesion measures 1.5x1x1cm. superior margin 1.6cminferior margin 1.5cmmedial margin 1.4cmlateral margin 1.8cmdeep margin 0.3cm,a) left axillary sentinel nodes:5 lymph nodes show no deposits of tumorb) left breast lump wide excision:tumor : composed of pleomorphic cells with hyperchromatic nucleus and scanty cytoplasm grade tubule formation lt 10 3nuclear pleomorphism 1mitotic figures 2 6 9 ductal carcinoma in situ is not presentlymphovascular invasion is not presentperineural invasion is not presentresected margin superior margin free of tumorinferior margin free of tumormedial margin free of tumorlateral margin free of tumor,a) left axillary sentinel nodes:5 nodes no deposits of tumorb) left breast lump wide excision :invasive ductal carcinoma nuclear grade iimaximum dimension of tumor is 1.5x1x1cm.lymphovascular invasion is not presentductal carcinoma in situ is not presentall resected margins are free of tumorpathological stage pt1n0
MR160010285,mass in left breast carcinoma breast,biopsy from left breast,received 4 grey white to grey brown linear cores measuring 0.6 to 0.8 cm.entire tissue processed,linear cores of breast tissue harboring a neoplasm arranged as sheets islands and in ductular pattern.the neoplastic cells have hyperchromatic to vesicular nuclei conspicuous nucleoli and moderate cytoplasm. large foci of necrosis seen.,invasive carcinoma left breast:grade 2 (7 9)tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR160010306,case of lump in left breast carcinoma left breast,biopsy from left breast mass lesion.,received 4 tiny grey white tissue fragments altogether measuring 0.4x0.3x0.2 cm.entire tissue processed.,section show very tiny tissue fragments predominantly comprised of blood clot fibrin and occasional clusters of epithelial cells.,tissue inadequate for opinion.suggest repeat biopsy.
MR160010333,right breast mass carcinoma breast,biopsy from right breast mass.,received 3 grey white to grey brown linear cores measuring 0.3 to 0.8 cm.entire tissue processed.,section from right breast shows mildly pleomorphic cells arranged in clusters and cords. the cells show hyperchromatic nucleus and scanty eosinophilic cytoplasm. signet ring cell morphology noted. stroma shows hyalinisation.,invasive carcinoma with lobular features grade i.mbr 3+1+1 5 9tubular formation 3nuclear pleomorphism 1mitotic figures 1 5 9
MR160010354,mass in right breast carcinoma breast,biopsy from breast mass,received 3 grey white to grey brown linear cores measuring 0.7 to 1cm.entire tissue processed.,section from linear cores of breast parenchyma harboring a cellular lesion arranged in solid sheets cords and trabecular. cells have scant to moderate cytoplasm hyperchromatic pleomorphic nuclei. mitotic figures are discerned.,core biopsy right breast mass:invasive carcinoma probably of ductal origin with nuclear grade ii.
MR160010435,carcinoma left breast t2 n0.,a) sentinel lymph node.b) wide local excision left breast lump.,a) received multiple fibrofatty tissue altogether measuring 3x3x1.5cm. cut surface largest lymph node measuring 1.8x1x1cm. cut surface fatty infiltration.b) received lumpectomy specimen measuring 8x7x4cm. cut surface shows grey white lesion measuring 1.8x1.7x1.5cm. skin ellipse 1.8x0.5cm.distance from margins :superior : 2cm.inferior : 1.5cm.medial :2cm.lateral : 2cm.deep : 0.2cm.,a) section show lymph nodes displaying reactive follicular hyperplasia. no atypical cells seen. isolated four lymph nodes negative for malignancy (0 4).b) multiple section from the breast parenchyma show a neoplastic infiltrative lesion arranged in cords tubules and in diffuse sheets. cells exhibit moderate to marked nuclear pleomorphism high n c ratio vesicular nuclei inconspicuous to prominent nucleoli. few with dispersed stripped chromatin and moderate to abundant eosinophilic cytoplasm. mitotic figures discerned. peritumoral lymphocytic infiltration seen. areas of necrosis seen. ductal carcinoma in situ seen with comedonecrosis. lymphovascular invasion seen.,a) sentinel lymph node :four lymph nodes isolated all are showing reactive hyperplasia.and negative for malignancy (0 4).b) left breast lumpectomy :invasive ductal carcinoma .modified br score is 8 9 grade iii.tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9 tumor measures 1.8cm in greatest dimension.ductal carcinoma in situ with comedo necrosis seen.lymphovascular invasion identified.perineural invasion not identified.all margins of resection are free of tumor.
MR160010487,right breast lump possibility of carcinoma breast.,biopsy from right breast lump,received 4 grey white linear cores measures 1 1.5cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as sheets and islands. the neoplastic cells exhibit moderate nuclear pleomorphism. conspicuous nucleoli and moderate cytoplasm. the intervening stroma is scant.,biopsy from right breast lump:invasive carcinoma grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160010497,carcinoma left breast,a) wide local excisionb) sentinel lymph nodesc) revised medial margin,a) received lumpectomy specimen measures 4.8x4.5x2cm on serial cut surface shows grey white tumor measures 2x1.8x1.2cm.located at the following distances from the respective margins: superior margin 0.8cminferior margin 1cmmedial margin 0.3cmlateral margin 2.5cmopposite to skin 0.5cmskin 0.1mgrossly skin not identifiedb) received fibrofatty tissue measures 3x2.8x1.8cm 2 lymph nodes shows dye each measures 0.7x0.6x0.5cm(isolated 6 lymph nodes).c) received fibrofatty tissue measures 2x1x1cm. with one surface inked.,a) wide local excision:tumor bed: tumor is composed of pleomorphic to oval cells with hyperchromatic nucleus and scanty cytoplasm.invasive dcutal carcinoma.grade tubule formation 3nuclear pleomorphism 2mitotic figures 2 mbr score 7 9 ductal carcinoma in situ is not presentlymphovascular invasion is not presentperineural invasion is not present.resected margins : superior margin free from tumorinferior margin free of tumormedial margin shows epithelial hyperplasia and atypical hyperplasia free of tumorlateral margin free of tumordeep margin free of tumor b) sentinel lymph nodes:6 nodes no deposits of tumorc) revised medial margin:free of tumor.,a) wide local excision:invasive ductal carcinomamaximum dimension of the tumor is 2x1.8x1.2cm.nuclear grade iiductal carcinoma in situ is not presentlymphovascular invasion is not present perineural invasion is not present.resected margins : superior inferior lateral and deep margin free of tumorb) sentinel lymph nodes:6 nodes no deposits of tumorc) revised medial margin:free of tumor.pathological stage pt1n0.
MR160010581,case of lump in right breast carcinoma right breast,biopsy from right breast lesion,received 3 grey white to grey brown linear cores measuring 0.7 to 0.8cm.entire tissue processed.,section shows linear cores of breast parenchyma harboring a cellular lesion arranged in solid sheets cords and trabecular. cells have scant cytoplasm hyperchromatic pleomorphic nuclei. mitotic figures are discerned. intervening stroma shows desmoplasia and spane mononuclear infiltrate.,core biopsy right breast mass:invasive ductal carcinoma nuclear grade 2.
MR160010583,complex cyst in left breast carcinoma breast,biopsy from left breast lesion.,received six grey white linear cores measuring 0.5 to 0.7 cm.entire tissue processed.,fragmented linear cores of tissue exhibiting closely packed acini and ducts. lined by cuboidal cells. foci of cells demonstrate vascular nuclei and mild atypia. apocrine change is noted. there is a rich intervening vascular network.,biopsy from left breast lesion:feature are suggestive of proliferative breast lesion showing florid adenosis with focus of atypical ductal hyperplasia.no definite evidence of malignancy is seen.suggest excision of the lesion for further confirmation.
MR160010587,previous operated carcinoma right breast 11yrs back.now locally recurrent skin nodules + chest wall,biopsy from skin nodule right chest wall,received 2 skin covered soft tissue bits larger measuring 1.5x1.3x0.9 cm.smaller measuring 0.8x0.7x0.5 cm.entire tissue processed.,section shows skin with underlying dermis harboring a neoplasm arranged as clusters and cords. the neoplastic cells have uniform round nuclei and moderate cytoplasm. probable lymphovascular emboli seen.,invasive carcinoma biopsy skin nodule right chest wall.
MR160010639,mass in right breast carcinoma breast.,biopsy from right breast mass.,received 4 grey white linear cores measuring 0.6 to 1 cm.entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in nests and diffuse sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast mass core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR160010659,mass in left breast carcinoma breast phyllodes,biopsy from left breast mass.,received 4 grey white linear cores measuring 0.5 to 1cm.entire tissue processed.,section shows cores of tissue with few hyperplastic ductules lined by cuboidal epithelial cells. stroma is fibrocollagenous. no atypia is seen.,left breast mass core biopsy:feature suggestive of proliferative breast disease fibroadenoma.suggest excision of the lump for further confirmation
MR160010680,lump right breast.,a) right breast.b) sentinel lymph node.c) revised deep margin.d) revised superior margin.,a) received lumpectomy specimen measuring 11x9x4cm. cut surface shows grey white area measuring 2.5x2.5x2.2cm. another grey white area measuring 1.2x1x1cm. distance from deep 1.5cm.distance from margins :superior : 25cm.inferior : 3cm.medial : 6cm.lateral : 1cm.deep 0.1cm.b) received lfibrofatty tissue measuring 4.8x4.5x1.5cm.largest lymph node measuring 1.5xx0.8cm. cut surface fatty infiltrates. entire tissue processed.c) received fibrofatty tissue measuring 5x4x1.5cm with one surface inked. p e.d) received fibrofatty tissue measuring 4xx0.8cm with one surface inked. entire tissue processed.,a) section from tumor shows breast parenchyma infiltrated by a neoplasm arranged as tubules cords and clusters. the neoplastic cells have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is fibrous. lymphovascular emboli not seen. superior inferior medial lateral and deep margins are free of tumor.overlying skin : free of tumor.b) 3 lymph nodes isolated are free of tumor.c) section shows fibrofatty and fibromuscular tissue which is free of tumor.d) section shows fibrofatty tissue with no significant pathology.4 lymph nodes isolated are free of tumor.,a) infiltrating ductal carcinoma right breast.modified br score is 7 9.tubular formation 3.nuclear pleomorphism : 2.mitotic figures 2 7 9 tumor size : 2.5x2.5x2.2cm.perineural invasion seen.no lymphovascular emboli seen. all resected margins are free of tumor.overlying skin : free of tumor.b) 3 sentinel lymph nodes isolated are free of tumor.c) revised deep margin : free of tumor.d) revised superior margin free of tumor 4 lymph nodes isolated are free of tumor
MR160010708,left breast carcinoma,a) lumpectomy wide local excisionb) further lumpectomy specimen wide excisionc) revised lateral margind) revised superior margine) left axillary lymph nodes,a) lumpectomy wide local excisionreceived lumpectomy specimen measures 6.5x6x1.5cm skin ellipse measures 3x0.5cm cut surface no solid lesion noted.located at the following distances from the respective margins: superior margin 1.2cminferior margin 2.2cmmedial margin 2cmlateral margin 1.8cmdeep margin 0.5cmb) received single fibrofatty tissue measures 4.5x5x2cm.on cut opening a grey white lesion noted measures 1.5x0.8x0.6cm. located at the following distances from the respective margins : superior margin 0.5cmlateral margin 2cmmedial margin 2.5cmlateral margin 2cmdeep margin 1cmc) revised lateral margin:received fibrofatty tissue measures 3.2x2x0.8cm one surface inked blue.d) revised superior margin:received single fibrofatty tissue measures 3.5x2x1cm with one surface inked.e) left axillary lymph nodes:received multiple fibrofatty tissue measures 9x6x2.5cm largest lymph nodes measures 1x1x0.5cm cut surface shows grey brown.,a) lumpectomy wide local excision:no residual viable tumor present dense hyalinisation sparse mononuclear cellular infiltration seen.resected margins and skin unremarkable free of tumor.b) further lumpectomy specimen wide excision:small focus of tumor present measuring 1.5x0.6x0.8cm with invasive ductal carcinomanuclear grade tubule formation 3nuclear pleomorphism 2mitotic figures 2 nuclear grade 7 9 ductal carcinoma in situ is not present.lymphovascular invasion is not present.resected margins superior margin free of tumorinferior margin free of tumormedial margin free of tumorlateral margin shows epithelial hyperplasia free of tumor.deep margin free of tumorc) revised lateral margin:free of tumord) revised superior margin:free of tumore) left axillary lymph nodes :16 nodes no deposits of tumor.,a) lumpectomy wide local excision:no residual tumor present.all resected margins skin unremarkable.b) further lumpectomy specimen wide excision:viable residual tumor presentinvasive ductal carcinomamaximum dimension of tumor is 1.5x0.8cmnuclear grade iiductal carcinoma in situ is not presentlymphovascular invasion is not presentresected margins superior inferior lateral medial and deep margins free of tumorc) revised lateral margin:free of tumord) revised superior margin:free of tumore) left axillary lymph nodes:16 nodes no deposits of tumor.
MR160010757,case of lump in right breastusg suggestive of carcinoma right breast,biopsy form right breast mass,received 2 grey white linear cores measuring 1 to 1.4 cm. entire tissue processed.,section shows cores of breast parenchyma harboring a lesion arranged in nests and cords comprising of pleomorphic cells with hyperchromatic angulated nuclei and scanty to moderate cytoplasm. stroma shows extensive fibrosis and hyalinisation.,right breast mass biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score 6(3+2+1).
MR160010798,mass in left breast carcinoma breast,biopsy from left breast mass,received 4 grey white linear cores measuring 0.8 to 1 cm.entire tissue processed,section show linear cores of tissue harboring a neoplastic lesion arranged in cords and sheets. individual cells have pleomorphic round to oval hyperchromatic nuclei inconspicous nucleoli and moderate amount of cytoplasm. stroma show hyalinisation with scattered inflammatory cells.,left breast mass core biopsy:invasive ductal carcinoma grade ii.modified br score (3+2+1) 6tubular formation 3nuclear pleomorphism 2mitotic figures 1 6
MR160010801,mass in right breast carcinoma breast,biopsy form right breast mass.,received 3 grey white linear cores measuring 1 to 1.2 cm.entire tissue processed.,section shows cores of breast parenchyma infiltrated by a lesion arranged in nests and cords comprising of pleomorphic cells with round to oval hyperchromatic nuclei and scanty cytoplasm. stroma shows fibrosis and areas of hemorrhage.,right breast mass biopsy:invasive ductal carcinoma grade 2modified br score 2+2+2 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR160010870,carcinoma left breast post nact.,left modified radical mastectomy,laterality : left : medial to lateral 24 cm :superficial to deep 4cm :superior to inferior 19 cmskin ellipse :14.5x9.5cmnipple :normalscar surgical defect :not seen.tumor :multipletumor size :tumor (1) measuring 2.5x1.cm.tumor (2) measuring 1.8x1.5x1.5cm.tumor (3) measuring 1x1x0.5cmlocation of tumor : tumor (1) lower outer quadrant tumor (2 ) upper inner quadrant tumor (3)upper inner quadrnatmargins of tumor :ill defineddeep margin from :tumor 1 2cm tumor 2 2cm tumor 3 1cmmuscle :presentadjacent breast :fibrofattyaxillary tail :present measuring 6x5x2cm.size of largest node :2x1x0.4cm cut surface grey white to grey brown.distance between tumor one and tumor 2 is 4.5cm. distance between tumor one and tumor 2 is 1cm between tumor one and tumor 2 is 3cm,section from tumor show breast parenchyma harboring a neoplasm arranged as tubules cords and in cribriform pattern. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. lymphovascular emboli seen. the intervening stroma is desmoplastic. foci of high grade solid comedonecrosis and cribriform ductal carcinoma in situ seen.deep margin free of tumornipple free of tumor3 out of 17 lymph nodes isolated show metastatic deposits of tumor.perinodal spread is seen.greatest tumor dimension 1cm,left breast left modified radical mastectomymulticentric invasive ductal carcinoma grade 2modified radical bloom richardson score is 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2tumor in lower outer quadrant measures 2.5x2x1cmtumor in outer inner quadrant measures 1.8x1.5x1.5cmtumor in upper inner quadrant measures 1x1x0.5cmductal carcinoma in situ comedonecrosis and cribriform patternlymphovascular invasion seenperineural invasion is not seenposterior resection margin is free of tumor.nipple and areola is free of tumorlymph nodes 17 lymph nodes metastasis : 3(3 17).greatest tumor dimension 1cmperinodal spread is seen
MR160010913,case of lump in right breast carcinoma right breast,biopsy from right breast.,received 3 grey white linear cores measuring 1.2 to 1.4 cm.entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR160010918,carcinoma right breast multiple nodular in both lungs metastasis,biopsy from right lung.,received 6 grey white linear cores measures 1 1.5cm. entire tissue processed.,section studied show lung parenchyma harboring an infiltrating lesion arranged in nests and sheets. the cells are round to ovoid having moderate amount of pale eosinophilic to clear cytoplasm hyperchromatic pleomorphic nucleus with prominent nucleoli. mitotic figures are discerned. stroma is desmoplastic with lymphomononuclear infiltrates. areas of hemorrhage and necrosis are seen.,biopsy from right lung:metastatic deposits in a known case of carcinoma breast.
MR160010957,lumpectomy 1 year back in left breast now left breast lump periareolar 7 0 clock position carcinoma.,biopsy from left breast lesion,received multiple tiny grey whiten tiny grey white to grey brown linear cores measuring 0.3 to 0.5 cm.entire tissue processed.,fragmented linear cores of tissue demonstrating papillary proliferation of cuboidal to oval cells harboring vesicular nuclei exhibiting moderate atypia and eosinophilic cytoplasm. mitotic figures are discerned. there are foci of necrosis hemorrhage and mixed inflammatory infiltrate. no definite evidence of invasive malignancy is seen.,biopsy from left breast lesion:suggestive of ductal carcinoma in situ of papillary pattern with intermediate nuclear grade.suggest excision of the lump for further confirmation of the invasive component.
MR160010960,case of lump left breast carcinoma left breast,biopsy from left breast mass,received 3 grey white linear cores measuring 0.7 to 1 cm.entire tissue processed.,section linear cores of tissue harboring a neoplastic lesion arranged in sheets and cord infiltrating stroma. individual cells have round to oval pleomorphic hyperchromatic nuclei and moderate amount of cytoplasm. stroma show hyalinisation.,left breast mass core biopsy:invasive carcinoma nuclear grade ii.
MR160010965,case of lump in left breast carcinoma left breast,biopsy from left breast mass.,received 4 grey white linear cores measuring 0.5 to 1 cm.entire tissue processed,section shows cores of breast parenchyma displaying glandular proliferation few dilated glands lymphoplasmacytic infiltrate and large areas of calcification. foci of cells show nuclear atypia infiltrating the stroma.,left breast mass core biopsy:suggestive of invasive carcinoma with background adenosis.suggest ihc for confirmation
MR160010975,left breast lump carcinoma breast,left breast lump,received multiple grey white linear cores measures 0.7 to cm.entire tissue is processed.,section shows cores of breast parenchyma with an infiltrative lesion arranged in vague glandular and papillary pattern. cells exhibit round to oval vesicular nuclei inconspicuous nucleoli and moderate eosinophilic cytoplasm. stroma shows dense lymphoplasmacytic infiltrate.,left breast lump:invasive carcinomambr score 7 (3+2+2)
MR160010994,known case of carcinoma breastbilateral ovarian masses.,a) peritoneal biopsyb) peritoneal deposit on uterovesical fold and surface of uterusc) ascites for cytology,a) received multiple grey white soft tissue bits measures 1.5x1x0.5cm. surface show necrosis. entire tissue is processed.b) received multiple grey white soft tissue bits altogether measures 1x0.5x0.5cm. entire tissue is processed.,a) b) section demonstrates papillary proliferation of cuboidal to low columnar cells exhibiting areas of stratification and moderate atypia amidst necroinflammatory infiltrate. atypical mitotic figures and brisk mitotic activity are discerned. there is a rich vascular channels.,a) peritoneal biopsy b) peritoneal deposit on uterovesical fold and surface of uterus :deposits of papillary serous carcinoma suggestive of high grade tumortesting for hereditary cancer panel (brca brca2) is suggested
MR160011006,mass in right breast carcinoma breast,biopsy from right breast mass.,received 3 grey white linear cores measuring 1 to 1.2 cm.entire tissue processed,section show linear cores of breast parenchyma harboring a neoplastic lesion arranged in tubules and cord with cells having round to oval hyperchromatic nuclei inconspicuous nucleoli and moderate amount of cytoplasm. stroma show hyalinisation. adjacent parenchyma show adenosis,right breast mass core biopsy:invasive ductal carcinoma grade ii.modified br score (3+2+1) 6tubular formation 3nuclear pleomorphism 2mitotic figures 1 6
MR160011007,case of lump in left breast carcinoma left breast,biopsy from left breast,received multiple grey white linear cores measures 1 to 1.5 cm. entire tissue is processed.,section shows cores of breast tissue infiltrated by tumor cells in tubules nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy :invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR160011036,carcinoma breast post treatment,biopsy from lung nodule.,received multiple grey white to grey brown linear cores measures 0.6 to 0.8 cm. entire tissue processed.,section shows linear cores of lung parenchyma with a lesion arranged in glandular pattern and nests. glands show inspissated eosinophilic secretions . the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. few nests of cells have abundant amount of vacuolated cytoplasm. interspersed inflammatory infiltrate seen.,lung nodule biopsy.adenocarcinoma. secondary primarysuggest ihc
MR160011093,lump left breast,a) lumpectomy left breast.b) sentinel lymph nodesc) left mastectomy,a) received lumpectomy specimen measures 8x4.5x2.4cm with one surface inked.cut section shows tumor is measuring 2x2x1.5cm with dcisb) received fibrofatty tissue measures 5x1.5x0.6cm isolated 5 lymphnodes4 lymph nodes inkedc) laterality : left total dimensions : medial lateral 17cm superficial deep 5cm superior inferior 17cmskin ellipse : 11x8cm nipple : normal tumor : no residual tumorsurgical defect : 6cm seen in upper outer quadrant(1 o position) located 2cm above and lateral to nipple and areola location of tumor : lumpectomy cavity upper and outer quadrant no solid area seen.margins of tumor : fibrofatty deep margin : 5cm muscle : absent adjacent breast : fibrofatty axillary tail : absent,a) lumpectomy:multiple sections from the tumor shows focal areas of invasive ductal carcinoma. extensive areas of ductal carcinoma in situ solid type low grademaximum dimension of tumor is 2x2cm.invasive ductal carcinomamaximum dimension of invasive ductal carcinoma is 0.8cmmaximum dimension of ductal carcinoma in situ is 1.2cm.lymphovascular invasion is not presentperineural invasion is present.invasive ductal carcinoma.tubule formation : 2mitotic figures : 1nuclear pleomorphism : 1 mbr score 4 9 grade ii.tumor is extending upto the marginb) sentinel lymph nodes : 5 nodes no deposits of tumor,left breast left modified radical mastectomy: lumpectomy bed: shows fibrofatty tissue and focal hemorrhagic areas. no evidence of residual tumor.posterior resection margin is free of tumornipple and areola is unremarkable
MR160011180,left breast lump ( 6 o clock) carcinoma breast.,biopsy from left breast,received 5 grey white linear cores measuring 1 to 1.3 cm.entire tissue processed.,section shows breast parenchyma with a neoplastic lesion arranged in cords and sheets. individual cells have pleomorphic round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stromal show hyalinisation and desmoplasia. adjacent breast show ductal hyperplasia crush artifacts noted.,left breast biopsy:invasive carcinoma nuclear grade 2.
MR160011272,left breast carcinoma,a) left breast left breast conservative surgeryb) revised lateral margin.c) revised base. d) left axillary dissection.,a) received single fibrofatty tissue measures 5 x 3.5 x 2.5 cm. skin ellipse measures 3.5 x 0.7 cm cut surface shows a grey white lesion measures 1.7 x 1 x 1 cm. located at the following distances from the respective margins: superior margin 1.5 cminferior margin 1.7 cmmedial margin 2 cmlateral margin 1 cmdeep margin 0.2 cmrepresentative sections are submitted.b) received single fibrofatty tissue measures 4.5x2x1cm with one surface inked.c) received single fibrofatty tissue with one surface inked measures 2x1x0.5cmd) received single fibrofatty tissue measures 5.5x5x2.5cm. largest lymph node measures 2x1x1cm. cut surface shows fatty infiltration,section from tumor shows cells in nests cords and diffuse sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular invasion or perineural invasion is not seen.,a) left breast lump left breast conservative surgery :invasive ductal carcinoma grade 2. tumor measures 1.7 cm in greatest dimension lymphovascular invasion is not seen perineural invasion is not seen. ductal carcinoma in situ of solid and cribriform pattern with intermediate nuclear grade is seen. all margins of resection are free of tumorb) revised lateral margin :negative for malignancyc) revised base :negative for malignancyd) left axillary dissection :nine lymph nodes are identified negative for malignancy(0 9).pathological stage : pt1cn0
MR160011294,right breast lump carcinoma.,biopsy from right breast lump,received three grey white to grey brown linear cores measuring 0.8 1 cm.entire tissue processed.,h amp e stained section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in sheets nests and tubules. cells have moderate amount of cytoplasm pleomorphic hyperchromatic nuclei. mitotic figures are discerned. stroma shows desmoplasia and necrosis.,right breast lump biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR160011307,left breast lump carcinoma.,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 1 1.4 cm.entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged as tubules and clusters. the neoplastic cells exhibit moderate nuclear pleomophism hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,invasive ductal carcinoma biopsy left breast.grade 2(6 9).tubular formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR160011316,carcinoma left breast,a) left breast left breast conservative surgery(post chemotherapy)b) revised deep marginc) left axillary lymph node dissection,a) received lumpectomy specimen measures 7 x 6 x 5 cm skin ellipse measures 4.5 x 1.2 cm scarpresent measures 4.5 cm. on serially slicing the specimen shows a grey white lesion measures 3.2 x 2.5 x 1 cm. located at the following distances from the respective margins:superior margin 1.5cminferior margin 1.5cmmedial margin 1cmlateral margin 2cmdeep margin 0.3cmrepresentative sections are submitted.b) received fibromuscular tissue measures 6 x 1 x 0.5 cm. entire tissue is processedc) received fibrofatty tissue measures 8 x 6 x 2.5 cm largest lymph node measures 2 x 1 x 0.5 cm cut surface shows fatty infiltration,section shows residual tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular invasion or perineural invasion is not identified. areas of necrosisare seen. treatment related changes are seen.,a) left breast left breast conservative surgery(post chemotherapy) :residual invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). tumor measures 3.2 cm in the greatest dimension lymphovascular invasion is not identified perineural invasion is not identified ductal carcinoma in situ component is not seen all margins of resection with overlying skin are free of tumorb) revised deep margin :negative for malignancyc) left axillary lymph node dissection :eighteen lymph nodes are identified negative for malignancy(0 18)pathological stage : ypt2n0
MR160011389,carcinoma left breast.,left breast left modified radical mastectomy.,received in : formalinprocedure : modified radical mastectomy laterality : left total dimensions : medial to lateral : 21cm. superficial to deep : 4cm. superior to inferior : 16cm.skin ellipse : 14 x 7 cm. nipple :normal scar skin shows a depressed area 2.5 cm medial to nipple (corresponding to tumor).tumor : single.tumour size : 2 x 1.5 x 1.5c m. location of tumor : upper inner quadrant.margins of tumor : ill defined deep margin : 1.3cm.muscle : absent adjacent breast : fibrofatty. axillary tail :6.5 x 4 x 1.5 cm.total number of nodes : 12 size of largest node : 2.4 x 1.2 x 1 cm. cut surface grey brown.representative sections are submitted.,section shows tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular and perineural invasion are identified.,left breast left modified radical mastectomy: invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). tumour is unifocal and is located in the upper inner quadrant. tumor measures 2 cm in greatest dimension. lymphovascular invasion is identified. perineural invasion is identified. ductal carcinoma in situ is not seen. posterior resection margin is free of tumor. nipple and areola is are free of tumor.lymph nodes:nine out of eighteen lymph nodes shows metastatic tumour deposits with extranodal extension(9 18). size of the largest tumor deposit measures 1.3 cm in greatest dimension.pathological stage : pt1cn2a
MR160011399,right lung lesion carcinoma,biopsy from right lung lesion,received multiple grey to grey brown cores measures 0.8 to 1.2cm.,linear cores of tissue infiltrated by compact nests islands of polygonal to oval neoplastic cells exhibiting moderate nuclear pleomorphism eosinophilic cytoplasm and notable mitotic activity. prominent areas of necrosis are noted.,biopsy from right lung lesion poorly differentiated carcinoma squamous cell carcinomahowever a remote possibility of metastatic from breast may please be ruled outsuggest ihcplease correlate with clinical findings
MR160011425,carcinoma right breast post breast conservative surgery + rt with right axillary nodal recurrence.,excised right axillary nodal mass.,received single fibrofatty tissue 4.5x3x2.5cm. cutsurface shows tumor.mass measures 2x1.2x1.0cm.,multiple section studied shows large nodal mass showing clumps groups and sheets of pleomorphic cells with hyperchromatic nucleus with eosinophilic cytoplasm. in focal areas ductular formation is present. plenty of mitotic figures are present. focal areas of necrosis is seen. surrounding the tumor normal ductal epithelium is present showing cystic dilatation of ducts. no lymphnode structure is present or lymphnoid cells seen.,excised right axillary mass: invasive ductal carcinoma axillary mass recurrence. the size of the mass measuring 2x1.2x1cm.
MR160011437,right breast lump carcinoma breast,biopsy from right breast lump,received multiple grey white linear cores measures 1 to 1.2cm. entire tissue is processed.,linear cores of breast parenchyma exhibiting focal ductal proliferation of round to oval cells demonstrating moderate nuclear pleomorphism and eosinophilic cytoplasm. adjacent areas show ducts and stroma with focal lymphocytic infiltrate.no definite invasion is seen in the material submitted,biopsy from right breast lump:ductal carcinoma in situ (dcis) high gradeplease correlate with clinical findings
MR160011474,mass in left breast carcinoma breast.,biopsy from left breast lump.,received 3 greywhite linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows cores of breast parenchyma with an infiltrative lesion in tubules. cells exhibit moderate nuclei and moderate cytoplasm. myoepithelial cell layer absent. areas of hyalinisation cystic change noted.,left breast:suggestive of invasive ductal carcinoma grade 2.tubule formation : 2nuclear pleomorphism : 1mitotic figures : 1 4 9
MR160011489,mass in left breast carcinoma breast,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 1 1.3 cm.entire tissue processed.,section shows cores of breast parenchyma with foci of infiltration by atypical cells arranged in cords and tubules. cells exhibit mild to moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. areas of hyalinization and sclerosis noted.,left breast:invasive carcinoma grade ii (6 9)modified br (6 9)tubular formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR160011507,carcinoma left breast.,a) left breast left modified radical mastectomy.b) left level iii lymph nodes.c) revised deep margin.,a) received in : formalin.procedure : left modified radical mastectomy.laterality : left. total dimensions : medial to lateral 22cm. superficial to deep 5cm. superior to inferior 16cm. skin ellipse : 14.5 x 10.5 cm. nipple : normal.scar surgical defect : not seen.tumor : singlelocation of tumor : upper inner quadrant. tumour size : 3 x 2.6 x 1.6 cm. margins of tumor : ill defined. deep margin : 0.8 cm.muscle : absent adjacent breast : fibrofatty tissue. axillary tail : 6.5 x 5.4 x 3 cm.total number of nodes : 10size of largest node : 1.6 x 1.2 x 1 cm cut surface grey brown.representative sections are submitted.b) received multiple fibrofatty tissue altogether measuring 1.8 x 1 x 0.6 cm. entire tissue is submitted.c) received a tissue bit measuring 7 x 1.6 x 0.5 cm. entire tissue is submitted.,section shows tumor cells in diffuse sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular or perineural invasion is not identified. areas of necrosis are seen. brisk mitotic activity is seen.,a) left breast left modified radical mastectomy: invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+2+3) tumor is unifocal and is located in the upper inner quadrant. tumor measures 3 cm in greatest dimension. lymphovascular invasion is not seen. perineural invasion is not seen. ductal carcinoma in situ is not seen. posterior resection margin is free of tumor. nipple and areola are free of tumor.lymph nodes:twelve lymph nodes are identified negative for malignancy(0 12) . b) level 3 lymph nodes:shows only fibrofatty tissue no lymph nodes are identified.negative for malignancy.c) revised deep margin:negative for malignancy.pathological stage : pt2n0summary: left mrm invasive ductal carcinoma grade 3.nodal metastases 0 12.
MR160011542,mass in right breast carcinoma breast,biopsy from right breast.,received 3 grey white linear cores measuring 1 1.3cm.entire tissue processed.,section shows cores of fibrofatty tissue with an infiltrative lesion arranged in cords nests and in sheets. cells exhibit moderate to marked nuclear pleomorphism vesicular nuclei inconspicuous nucleoli and moderate cytoplasm. mitotic figures discerned. areas of necrosis noted.,right breast:invasive ductal carcinoma grade ii.modified br score (7 9).tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9 areas of necrosis seen.
MR160011546,mass in right breast 3 0 clock.positive carcinoma breast.,biopsy from right breast.,received 3 grey white linear cores measuring 1 1.2cm.entire tissue processed.,section shows cores of fibrofatty tissue infiltrated by lymphocytes and few cores show scattered atypical cells with irregular hyperchromatic nuclei. areas of dense hyalinization and thickened blood vessels noted. at few foci. the atypical cells show pseudotraching and indian file appearance.,right breast:suggestive of invasive carcinoma with lobular features nuclear grade ii.
MR160011570,mass in right breast carcinoma breast,biopsy from right breast.,received 5 grey white to grey brown linear cores measuring 0.6 1 cm.entire tissue processed.,section show linear cores of tissue harboring a neoplastic lesion arranged is sheets. individual cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma show fibrous tissue bland stromal cells and lymphocytic infiltrate. congested and hyalinised blood vessels noted.,right breast core biopsy:invasive ductal carcinoma grade ii.modified br score (3+3+2) 7tubule formation 3nuclear pleomorphism 3mitotic figures 2 7
MR160011582,carcinoma right breast post mrm,biopsy from liver lesion,received multiple grey white linear cores measures 1.2 to 1.5cm. entire tissue processed.,section shows linear cores of tissue harboring a neoplastic lesion arranged in cords trabeculae and nests. the cells are pleomorphic with round to oval vesicular nuclei prominent nucleoli and moderate amount of cytoplasm. mitotic figures are seen. areas of hyalinisation seen.,liver lesion:metastatic deposit in a known case of carcinoma breast.
MR160011594,left breast carcinoma,a) left breast lumpectomyb) left axillary clearance,a) left breast lumpectomy :received fibrofatty tissue measures 7x4x2.9cm skin ellipse measures 5.5x1.2 cm gritty to cut shows a grey white to grey yellow area measures 1.5x1.5x1cmlocated at the following distances from the respective margins:superior margin 1.5cminferior margin 0.8cmmedial margin 4.5cmlateral margin 2.5cmdeep margin 1.0cmanother grey white circumscribed area measures 1x1x1cm present 3cm away from grey whitegritty areab) left axillary clearance:received multiple fibrofatty tissue altogether measures 7x4x3cm largest lymph node measures3.2x2x1.4cm cut surface shows grey white isolated 13 lymph nodes,a) left breast lumpectomy :tumor bed:the section shows areas of fibrosis necrosis and atrophic ducts with lymphocytes infiltration.there is no evidence of residual viable tumor presentresected margins : superior margin free of tumorinferior margin free of tumormedial margin free of tumorlateral margin free of tumordeep margin free of tumoranother circumscribed nodule shows fibroadenomab)left axillary clearance :3 nodes show metastatic deposits of tumor out of 13 nodesperinodal spread present,a) left breast lumpectomy:no residual viable tumor presentareas of fibrosis necrosis presentall resected margins are free of tumorb) left axillary clearancelymph nodes 3 nodes show metastatic deposits of viable tumor out of 13 nodesperinodal spread present
MR160011641,mass in left breast carcinoma breast.,biopsy from left breast.,received 4 grey white linear cores measuring 1 to 1.2 cm.entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged as cords clusters and tubules. the neoplastic cell exhibit moderate nuclear pleomorphism have vesicular nuclear conspicuous nucleoli and moderate cytoplasm. the intervening stroma is desmoplastic.,invasive ductal carcinoma biopsy left breast.grade 2(6 9).tubular formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR160011695,mass in right breast carcinoma breast,biopsy from right breast mass.,received 3 linear grey white cores measuring 1 to 1.2 cm.entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in nests and defuse sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast mass core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160011720,carcinoma right breast multicentric disease.,right modified radical mastectomy.,received in : formalin. time of receipt at lab : 11:55pm. time to formalin :procedure : mr mastectomy.laterality : right. total dimensions : medial to lateral 25cm. superficial to deep 5cm. superior to inferior 21cm. skin ellipse : 12x8cm. nipple : normal.scar surgical defect : not seen.tumor : 2 lesions identified cut surface tumour size : tumor measuring 2.5x1.5x1.5cm greywhite area measuring 2x1.5x1cm location of tumor : tumor upper outer quadrant greywhite area upper inner quadrant.distance between 2 lesions : 8cm. margins of tumor : infiltrative. deep margin :from one tumor:2cm from grey white lesion:1.5cmmuscle : present 4x2cm.adjacent breast : fibrofatty. axillary tail : 5x5x2cm.total number of nodes :12size of largest node : 1x1x0.5cm cut surface : fatty infiltration.,sections from two tumors show breast parenchyma harboring a neoplasm arranged in tubular pattern and as cords.the neoplastic cells have vesicular nuclei conspicuous nucleoli and moderate cytoplasm.extensive areas of high grade ductal carcinoma in situ solid comedo cribriform and papillary pattern are seen.lymphovascular emboli seen.deep margin: free of tumor.tissue between two tumors show foci of ductal carcinoma in situ and fibrocystic change.section from nipple : free of tumor.,right breast right modified radical mastectomy:multicentric tumor invasive ductal carcinoma grade 2.modified br score is 6 9.tubule formation: 2.nuclear pleomorphism : 2.mitotic figures: 2.tumor (located in the upper outer quadrant) measures 2.5 cm in greatest dimension . deep margin is 2cm away from tumor.tumor (located in upper inner quadrant) measures 2cm in greatest dimension .deep margin is 1.5cm away from tumor.ductal carcinoma in situ present(high grade).lymphovascular invasion seen.perineural invasion not seen.muscle is free of tumor.nipple and areola is free of tumor.lymph nodes: 12 lymph nodes metastasis: 0 (0 12) .
MR160011730,mass in right breast carcinoma breast,biopsy from right breast,received 4 grey white to grey brown linear cores measuring 0.6 1 cm.entire tissue processed.,section show linear cores of tissue with a neoplastic arranged in cords and islands. individual cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma show hyalinisation and lymphocytic infiltrate.,right breast core biopsy:invasive carcinoma nuclear grade ii.
MR160011736,duct ectasia left breast,microdochectomy left breast,received fibrofatty tissue measures 9x2.5x1.5cm. on serial sectioning a small grey white lesion measures 1x0.3x0.3cm. distance from nearest inked surface is 0.1cm. also seen few dilated ducts measures 1x0.5x0.8cm. distance from nearest inked surface is 0.2cm. also received in the same container fibrofatty tissue measures 3x2x1cm cut surface shows grey white nodular area measures 1.2x0.4x0.5cm. distance from nearest inked surface is 0.3cm.,sections show breast parenchyma with dilated ducts harboring a lesion where the cells are arranged in sheets and papillary growth pattern around fibrovascular cores. cells are monomorphic cohesive and filling the lumen. individual cells have moderate amount of eosinophilic granular cytoplasm round to oval vesicular nuclei with prominent nucleoli. myoepithelial layer noted. mitotic figures discerned : 2 3 hpf.,left breast microdochectomy : shows ductal carcinoma in situ solid pattern with intermediate nuclear grade.background shows features of intraductal papilloma and suspicious foci of invasion.suggest ihc for further confirmation.
MR160011758,mass in left breast carcinoma breast.,left breast mass core biopsy.,received 3 greywhite linear cores measuring 1 to 1.3 cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in cords and small nests . individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy :invasive carcinoma with lobular features grade 2. modified bloom richardson score is 6(3+2+1).
MR160011763,right breast lesion carcinoma.,biopsy from right breast.,received 4 grey white linear cores measuring 1 to 1.5 cm.entire tissue processed.,section from breast parenchyma shows multiple linear cores harboring a neoplastic lesion arranged in sheets nests. the cells have abundant eosinophilic cytoplasm with pleomorphic hyperchromatic nuclei. desmoplasia seen. areas of necrosis noted.,right breast biopsy:invasive ductal carcinoma grade ii (6 9)modified brtubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR160011812,left breast lump carcinoma.,biopsy from left breast lesion.,received 5 grey white linear cores measuring 1 to 1.5 cm.entire tissue processed.,linear cores of tissue exhibiting a neoplastic lesion arranged in nests and islands consisting of round to oval neoplastic cells demonstrating moderate nuclear pleomorphism and pale eosinophilic cytoplasm. there are areas of necrosis lymphocytic infiltrate and prominent fibrocollagenous stroma.,biopsy from left breast lesion:invasive ductal carcinoma grade ii with extensive ductal carcinoma in situ.tubular formation 2nuclear pleomorphism 2mitotic figures 2 mbr score 6 9
MR160011869,known case of carcinoma breast.d3 extradural mass with cord compression.,d2 d3 laminectomy and surgical decompression of tumor.,a) received multiple grey white soft tissue bits along with few bony fragments measures 2.5x2x0.4 cm entire tissue processed.b) received multiple grey white soft tissue bits along with few bony fragments measures 2.5x1.5x0.5 cm entire tissue processed.,section from a and b show multiple bony bits with an infiltrating lesion arranged in tubules cords and cribriform pattern consisting with neoplastic cells having round to oval pleomorphic vesicular nuclei and moderate eosinophilic cytoplasm. areas of fibrosis and hyalinization noted.,d2 d3 laminectomy :consistent with metastatic deposits in a known case of carcinoma breast.
MR160011870,left breast mass carcinoma.,biopsy from left breast mass.,received 4 greywhite linear core measuring 1 to 1.2cm. entire tissue processed.,section shows cores of breast parenchyma infiltrated by a lesion arranged in nests clusters and cords comprising of atypical cells with round to oval hyperchromatic nuclei with scanty to moderate cytoplasm. extracellular mucinous areas noted. comedo ductal carcinoma in situ seen. focal areas of necrosis seen.,left breast mass biopsy:invasive ductal carcinoma with ductal carcinoma in situ (solid and comedo type) along with mucinous differentiation.
MR160011881,right breast mass carcinoma.,biopsy from right breast,received 4 grey white linear cores measuring 0.8 to 1.2 cm.entire tissue processed.,section shows linear cores of tissue with lesion arranged in cords and sheets with cells having pleomorphic hyperchromatic nuclei and moderate amount. stroma show hyalinisation and dense lymphocytic infiltrate. areas of necrosis and crush artefacts noted.,right breast core biopsy:poorly differentiated malignancy.suggestive of invasive carcinoma nuclear grade ii.suggest work up.
MR160011886,right breast lesion carcinoma right breast.,biopsy from right breast.,received 4 grey white linear cores measuring 0.5 to 1.2 cm.entire tissue processed.,section show linear core of tissue showing liver parenchyma with a lesion arranged in nest. islands pseudo papillary pattern. individual cells have round to oval hyperchromatic nuclei and moderate to scanty cytoplasm. also seen are nest of large cells with similar nuclear features and abundant amount of pale eosinophilic cytoplasma. stroma shows fibrosis hyalinisation. areas of necrosis noted.,right breast core biopsy:invasive ductal carcinoma grade iimodified br score (3+2+1) 6ductal carcinoma in situ solid type seen.
MR160011893,right breast lesion carcinoma.,biopsy from right breast.,received 6 grey white linear cores measuring 0.6 to 1 cm.entire tissue processed.,section from breast parenchyma shows multiple fragments harboring a neoplastic lesion arranged in sheets. the cells show pleomorphic hyperchromatic nuclei with abundant eosinophilic cytoplasm. areas of necrosis fibrosis noted.,right breast biopsy:small focus of invasive ductal carcinoma grade ii (6 9)modified brtubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR160011899,carcinoma left breast.,a) sentinel lymph node biopsy(frozen section).b) left breast lump wide excision(frozen section).c) left breast left modified radical mastectomy.d) left axillary dissection.,a ) received fibrofatty tissue measuring 3.2 x 2 x 1 cm. isolated inked 2 lymph nodes ( sentinal nodes) largest lymph node measuring 1 x 1 x 0.9 cm. entire tissue processed.b) fresh tissue received : yeslaterality : leftspecimen orientation : orientated specimen size : 8 x 6.5 x 2.5 cm.skin : presentskin dimensions : 6.5 x 0.5 cm.lesion(s) : presentnumber of macroscopically visible lesions : single grey white lesion.lesion dimensions : 1.8 x 1 x 1 cm.distance of lesion from margins : superior :1.8 cm. inferior : 1.5 cm. medial :1.0 cm. lateral : 1.2 cm. deep : 1.2 cm.c) procedure : modified radical mastectomy(post lumpectomy).total dimensions : medial to lateral : 21 cm. superficial to deep : 6 cm. superior to inferior : 20 cm.skin ellipse : 18 x 12.5 cm.nipple : unremarkable.surgical defect : single defect seen. location of tumor : lumpectomy bed measuring 9 x 7.5 x 4.5 cm. adjacent lumpectomy bed shows fibrotic areas. representative sections are submitted.d) received multiple fibrofatty tissue measuring 6 x 4 x 2 cm. largest lymph node measuring 2 x 1.4 x 0.6 cm. cut surface grey white to grey brown. 11 lymph nodes isolated.,a) section from lymph node shows features of reactive follicular hyperplasia with increase in number of follicles.b) section studied from breast parenchyma shows a neoplastic lesion arranged in sheets lobules cords and trabeculae. the cells have moderate amount of cytoplasm pleomorphic vesicular nuclei and conspicuous nucleoli. adjacent parenchyma shows ductal carcinoma in situ with comedo type of necrosis. stroma shows desmoplasia.c) section from lumpectomy bed shows epithelial hyperplasia of the ducts and stromal fibrosis.d) section from lymph nodes shows features of reactive follicular hyperplasia.,a) sentinel lymph node biopsy(frozen section) :two lymph nodes are identified negative for malignancy(0 2).b) left breast lump wide excision(frozen section) :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2). tumour measures 1.8 cm in greatest dimension. lymphovascular invasion is not identified. perineural invasion is not identified. all margins of resection are free of tumour.c) left breast left modified radical mastectomy :no residual tumor seen. adjacent breast tissue shows fibrosis and inflammatory infiltrates. posterior resection margin is free of tumour. nipple and areola are free of tumour.d) left axillary dissection :nine lymph nodes identified negative for malignancy(0 9).
MR160011907,left breast mass carcinoma,biopsy from left breast lesion.,received 5 grey white linear core measuring 0.5 cm. entire tissue processed.,fragmented linear cores of tissue exhibiting few dyscohesive clusters of round to oval cells with centrally placed nuclei and moderate amount of eosinophilic cytoplasm amidst extensive areas of fibrocollagenous stroma.,biopsy from left breast lesion:shows occasional nests of atypical cells.suggest repeat biopsy or excision of the lump for further confirmation.
MR160011947,carcinoma left breast,a) left sentinel lymph nodeb) left modified radical mastectomy,a) left sentinel lymph node:received multiple fibrofatty tissue altogether measures 4x2.5x1cmidentified 5 lymph nodeslargest measures 1.3x1x0.5cm cut surface shows blue dyeb) left modified radical mastectomy:received in : formalin.procedure : mastectomy radical laterality : lefttotal dimensions : medial lateral : 22cm. superficial deep : 5cm. superior inferior : 17cm.skin ellipse : 14x9cm.nipple and areola : normal.scar surgical defect : not seen. tumor : grossly no obvious tumor seen solid and cystic areas are present with papillary like projectionmuscle : absent.total number of nodes : 13 nodes.size of largest node : 1x0.5x0.5cm. cut surface show fatty infiltration.axillary tail : 6x5x2cm.,sections demonstrate papillary proliferation of round to cuboidal cells with vesicular nuclei and moderate amount of eosinophilic cytoplasm. there is a rich intervening fibrovascular network.,b) left breast left modified radical mastectomy: invasive ductal carcinoma grade ii. modified br score is 6.tubule formation: 2nuclear pleomorphism: 2 mitotic figures: 2tumor measures 1.5x1cm in greatest dimension and is located in the central quadrant. ductal carcinoma in situ not present adjacent breast show intraductal papillomalymphovascular invasion not presentperineural invasion not presentposterior resection margin is free of tumornipple and areola is unremarkable.lymph nodes: 13 lymph nodes isolated show no metastatic deposits of tumor. (0 13) . a) sentinel lymph nodes 5 nodes no deposits of tumoraxillary lymph nodes 13 nodes no deposits of tumorsummary:left mrm invasive ductal carcinoma grade iilymph nodes: 13 lymph nodes isolated show no metastatic deposits of tumor. (0 13) . sentinel lymph nodes 5 nodes no deposits of tumorpathological stage :pt1 n0
MR160011962,carcinoma right breast,a) sentinel lymph nodesb) wide local excisionc) revised lateral margin,a) sentinel lymph nodes:received fibrofatty tissue measures 4x3x1cm 3 lymph nodes identified with ink. largest measures 2x1x0.8cm cut surface shows fatty infiltration.isolated total 5 lymph nodesb) wide local excision:received fibrofatty tissue measures 5.5x5x3cm skin ellipse measures 2.2x0.5cm cut surface shows grey white lesion measures 1.8x1.7x1cm located at the following distances from the respective margins: superior margin 1.5cminferior margin 2.2cmmedial margin 1.5cmlateral margin 2cmdeep margin 0.9cmc) received single fibrofatty tissue measures 3x2.5x0.5cm one surface inked blue.entire tissue is processed,a) sentinel lymph nodes:5 nodes isolated show reactive hyperplasia no deposits of tumorb) wide local excision:tumor multiple section shows pleomorphic oval to cuboidal cells with hyperchromatic nucleus and scanty cytoplasm. invasive ductal carcinoma.grade tubule formation 2nuclear pleomorphism 2mitotic figures 2 mbr score 6 9 ductal carcinoma in situ is not presentlymphovascular invasion is not presentresected margins superior margin free of tumorinferior margin free of tumormedial margin free of tumorlateral margin free of tumordeep margin free of tumor,breast conservative surgery:invasive ductal carcinomamaximum dimension of tumor is 1.8x1.7x1cm. nuclear grade iilymphovascular invasion is not presentall resected margins are free of tumoraxillary sentinel lymph nodes 5 nodes no deposits of tumorpathological stage pt1n0
MR160012034,left breast lump carcinoma,biopsy from left breast,received 5 grey white linear cores measuring 0.5 1 cm.entire tissue processed.,section shows cores of tissue infiltrated by a lesion arranged in cords nests and trabecular comprising of pleomorphic cells with round to oval hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. nests of apocrine cells are also noted. focal areas of necrosis noted. stroma shows hyalinisation and areas of hemorrhage.,left breast biopsy:invasive ductal carcinoma nuclear grade 2
MR160012038,case of lump in left breast carcinoma left breast.,biopsy from left breast,received 4 grey white linear cores measuring 1 to 1.2 cm.entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR160012054,right breast lump carcinoma.,biopsy from right breast,received 4 grey white linear cores measuring 0.7 1 cm.entire tissue processed.,section shows bones of tissue harboring a lesion arranged in nests cords and sheets comprising of atypical cells with pleomorphic round to oval hyperchromatic nucleus and moderate amount of eosinophilic cytoplasm. areas of necrosis seen.,right breast biopsy:invasive ductal carcinoma grade 2modified br score 7 9 (3+2+2)tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR160012057,carcinoma right breast post lumpectomy.,a) sentinel lymph node(frozen section).b) right breast right lumpectomy(frozen section).c) left oophorectomy.d) revised lateral margins.e) right axillary lymph nodes.,a) received multiple fibrofatty tissue altogether measuring 4.5 x 2.5 x 1 cm largest sentinel lymph node measuring 3 x 1 x 1 cm.cut surface : shows greywhite area with ink.identified 4 lymph nodes with blue ink. representative sections are submitted.b) fresh tissue received : yesnumber of specimens received : 1laterality : rightprocedure : breast conservative surgery(wle+sentinel lymph node biopsy)specimen orientation : orientatedspecimen size : medial lateral length 6.5cm superficial deep length 3 cm superior inferior length 5 cmskin : present skin dimensions : 3x0.5cm skin abnormalities : absentnipple : absentlesion(s) :presentnumber of macroscopically visible lesions : 1for each lesion (if gt 1 designate accordingly):lesion description : irregular greywhite fibrotic area. lesion dimensions : 1.5x1.2x0.5cm.distance of lesion from margins : superior 1.0 cm inferior 2.2 cm medial 1.5 cm lateral 1.5 cm deep 0.2 cmdistance of lesion to nearest margin : deep 0.2 cm other relevant macroscopic information : lateral margin shows a nodular area measuring 1x1x0.8cm cut surface : greywhite.adjacent fibrotic noted measuring 2.5x1x1.5cm.representative sections are submitted.c) received single ovary measuring 6x6x3.5cm. external surface : smooth.no capsular breach.cut surface : yielded brownish black fluid multilocular cystic hemorrhagic areas. representative sections are submitted.d) received fibrofatty tissue measuring 3.6 x 2 x 1 cm. entire tissue is processed.e) received fibrofatty tissue measuring 6 x 5.5 x 1.5 cm largest lymph node measuring 1.5 x 0.8 x 0.5 cm cut surface : greybrown. representative sections are submitted.,sections from breast parenchyma shows no residual tumour. adjacent breast tissue shows slit like compressed ducts lined by cuboidal to flattened epithelium with cells having round to oval bland nuclei and scant to moderate amount of cytoplasm. adjacent breast show adenosis ductal hyperplasia and fibrocystic change. margins of resection are free of tumor.,a) sentinel lymph node(frozen section) :six lymph nodes isolated negative for malignancy(0 6).b) right breast right lumpectomy(post lumpectomy)(frozen section):no residual invasive tumour is seen. adjacent breast tissue shows features of ductal hyperplasia and fibroadenoma. all margins of resection are free of tumor.c) left ovary left oophorectomy :features suggestive of benign cystic lesion.negative for malignancy.d) revised lateral margin :negative for malignancy.e) right axillary dissection :thirteen lymph nodes isolated negative for malignancy(0 13).
MR160012063,carcinoma right breast post lumpectomy.,right modified radical mastectomy.,received in : formalin. procedure : post lumpectomy mastectomy.laterality : right. total dimensions : medial to lateral 24cm. superficial to deep 6cm. superior to inferior 16cm. skin ellipse : 18x8cm. nipple :scar surgical defect :scare measuring 8.5cm is located just above the nipple areola complex extending from upper inner quadrant to upper outer quadrant.10 o clock to 10 o clock position. tumor : not identified grossly a cystic area measuring 5x2x1.5cm is located in the upper outer quadrant.deep margin : 2.5cm.muscle : absent adjacent breast : fibrofatty axillary tail : 7x6x3cm.total number of nodes : 12 nodes.size of largest node : 2.5x2x1cm cut surface : greywhite tumor deposit.,section shows breast parenchyma harboring a lesion arranged in sheets nests and cords comprising of atypical cells with round to oval vesicular pleomorphic nuclei and scanty and moderate cytoplasm.mitotic figures 2 3 hpf.stroma shows extensive fibrosis and giant cell aggregates.lymphovascular invasion is identified.,histopathologic examination:right breast right modified radical mastectomy: invasive ductal carcinoma grade 2.modified br score is 6 9.tubule formation: 3.nuclear pleomorphism: 2.mitotic figures: 1.tumor measures 5 cm in greatest dimension and is located in the upper outer quadrant. ductal carcinoma in situ is not seen.lymphovascular invasion is identified.perineural invasion is not identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: 13 lymph nodes metastasis: 03 (3 13) . summary: right mrm residual invasive ductal carcinoma grade 2.nodal metastases three out of thirteen lymph nodes show tumor deposits.
MR160012079,right breast lump (9 0 clock) carcinoma breast,biopsy from right breast.,received 4 grey white linear cores measuring 1 1.5 cm.entire tissue processed.,section from breast shows cores of tissue infiltrated by a lesion arranged i nests cores and trabecular comprising of cells with moderately pleomorphic hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. adjacent areas shows hyalinisation and fibrosis focal areas of necrosis seen.,right breast biopsy:invasive ductal carcinoma grade 2 modified br score 3+2+1 (6 9)tubular formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR160012128,left breast lump carcinoma,biopsy from left breast core.,received 6 grey white linear cores measuring 0.5 to 1.5 cm.entire tissue processed.,section studied shows linear cores of breast parenchyma infiltrated by tumour cells arranged in solid sheets nests and cords. individual cells have moderate amount of cytoplasm pleomorphic hyperchromatic nuclei and prominent nucleoli. mitotic figures and discerned. stroma shows fibrosis and inflammatory infiltrate.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1)
MR160012133,right breast ulcerative mass carcinoma right breast,biopsy from right breast,received multiple grey white linear cores measuring 0.5 to 1.5 cm.entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged as tubules and nests. the cells are ovoid to cuboidal with hyperchromatic pleomorphic nuclei inconspicuous nucleoli and moderate cytoplasm. atypical mitoses noted.,biopsy from right breast:invasive ductal carcinoma grade iimbr score is 6 9tubular formation 2 nuclear pleomorphism 2mitotic figures (4 5 10hpf) 2 6 9
MR160012158,left breast lump carcinoma,biopsy from left breast lesion.,received 5 grey white linear cores measuring 1 to 1.5 cm.entire tissue processed.,linear cores of tissue exhibiting a neoplastic lesion arranged in nests sheets islands and tubular configuration consisting of round to oval cells demonstrating moderate nuclear pleomorphism and pale eosinophilic cytoplasm amidst and desmoplastic stroma.,biopsy from let breast lesion:invasive ductal carcinoma grade ii score 6 9tubule formation 2 nuclear pleomorphism 2mitotic figures 2 6 9
MR160012209,left breast lump carcinoma.,biopsy from left breast.,received 4 grey white tissue core measuring 1 to 1.1 cm.entire tissue processed.,section shows breast parenchyma harboring in infiltrate lesion arranged in diffuse sheets and cords. cells exhibit moderate to marked nuclear pleomorphism round to oval vesicular nuclei prominent nucleoli and moderate eosinophilic cytoplasm. mitotic figures discerned. areas of necrosis noted. stroma shows marked lymphocytic infiltrate.,left breast:invasive ductal carcinoma. grade iiimodified br score (8 9)tubular formation 3nuclear pleomorphism 2mitotic figures 3 8 9
MR160012210,mass in right breast carcinoma breast.,biopsy from right breast.,received 3 grey white tissue core measuring 1.0 to 1.5 cm.entire tissue processed.,section shows an infiltrate lesion arranged in tubules and cords. cells exhibit moderate nuclear pleomorphism round to oval hyperchromatic nuclei and moderate cytoplasm. stroma shows mild inflammatory infiltrate.,right breast:invasive ductal carcinoma. grade imodified br score (5 9)tubular formation 1nuclear pleomorphism 2mitotic figures 2 5 9
MR160012214,mass in left breast carcinoma breast.,biopsy from left breast.,received 3 grey white linear cores measuring 1 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as islands and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is fibrous.,invasive ductal carcinoma biopsy from left breast.modified br score is 6 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160012216,carcinoma left breast,a)left breast wide local excisionb) left axillary lymph nodesc) level iii lymph nodes,a) left breast wide local excision:fresh tissue received : yesprocedure : left breast wide local excisionspecimen orientation : orientatedspecimen size : 6.5x4.5x1.5cmskin : presentskin dimension : 5x2cmskin abnormalities : absentnipple : absentlesion : presentnumber of macroscopically viable lesions : single grey white lesionlesion dimensions : 1x0.5x0.3cmlocated at the following distances from the respective margins:superior margin 3cminferior margin 2cmmedial margin 2.8cmlateral margin 1.2cmdeep margin 1cmb) left axillary lymph nodes:received multiple fibrofatty tissue altogether measures 6.5x5.5x2cm largest lymph node measures 1.6x1.4x0.6cm cut surface shows grey brown. dissected 20 nodes.c) level iii lymph nodes:received fibrofatty tissue measures 2x1x1cm dissected 2nodes.,a)left breast wide local excision:tumor bed: multiple section shows clumps groups and sheets of pleomorphic cells with hyperchromatic nucleus and scanty cytoplasm.invasive ductal carcinomasurrounding tumor fibrosis and giant cells are seen.grade tubule formation 3nuclear pleomorphism 2mitotic figures 2 79 nuclear grade iiductal carcinoma in situ present low gradelymphovascular invasion is presentperineural invasion not seen.resected margins superior margin free of tumorinferior margin free of tumormedial margin free of tumor.lateral margin free of tumordeep margin free of tumorb) left axillary lymph nodes:1 node shows metastatic deposits of viable tumor out of 20 nodes.perinodal spread is present.c) level iii lymph nodes:2 nodes no deposits of tumor.,a) left breast wide local excision :invasive ductal carcinomamaximum dimension of tumor is 1x0.5cmnuclear grade iiductal carcinoma in situ is present low grade(measuring 0.2cm)lymphovascular invasion is present.all resected margins are free of tumorb) left axillary lymph nodes:one node shows metastatic deposits of viable tumor out of 20 nodes.c) level iii lymph nodes:2 nodes no deposits of tumor.
MR160012237,mass in left breast phyllodes carcinoma breast,biopsy from left breast mass,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue is processed.,section shows linear cores of tissue infiltrated by a neoplastic lesion arranged in sheets and tubules. the cells have hyperchromatic pleomorphic round to oval nuclei inconspicuous nucleoli and moderate cytoplasm. atypical mitotic figures discerned.,biopsy from left breastinvasive ductal carcinoma grade iiimbr score 8 9tubule formation 3nuclear pleomorphism 2mitotic figures 3 8 9
MR160012253,left breast carcinoma.,a) sentinel lymph nodes.b) left breast.,a) received fibrofatty tissue measuring 4.5x2.5x0.8cm.b) received in : formalin.procedure : mastectomy.laterality : lefttotal dimensions : medial to lateral 15cm. superficial to deep 3.5cm. superior to inferior 14cm. skin ellipse : 8.5x4.5cm. nipple : normal.scar surgical defect : not seen.tumor : single greywhite granular ductal carcinoma in situ like(2x1x1cm).tumour size : 1x0.5x0.5cm(invasive component) location of tumor : central quadrant. margins of tumor : ill defined. deep margin : 0.8cm.muscle : absent adjacent breast : fibrofatty tissue. axillary tail : absent.,a) 3 sentinel lymph nodes isolated are free of tumor.b) multiple sections from breast show large areas of comedo and solid ductal carcinoma in situ.small focus of atypical cells with moderate nuclear pleomorphism and moderate cytoplasm arranged as clusters are seen.no lymphovascular invasion seen.moderate intertumoral lymphocytic response is seen.deep margin is free of tumor.nipple and areola : free of tumor.,b) invasive ductal carcinoma left breast.tumor size(invasive component) : 1x0.5x0.5cm.extensive high grade ductal carcinoma in situ component comedo and solid pattern(size:2x1x1cm).no lymphovascular invasion seen.uninvolved breast parenchyma shows fibrocystic change.deep margin is free of tumor.nipple and areola : free of tumor.a) 3 sentinel lymph nodes isolated are free of tumor.
MR160012266,right breast lump carcinoma,biopsy of right breast,received multiple grey white linear cores measures 0.5 to 1.2cm. entire tissue is processed.,section shows cores of breast parenchyma harboring an infiltrative lesion arranged in nests and cords exhibit moderate nuclear pleomorphism with round to oval hyperchromatic nuclei moderate eosinophilic cytoplasm. areas of myxoid change seen. stroma shows mild lymphocytic infiltrate.,biopsy from right breast:invasive carcinoma with nuclear grade 2.
MR160012295,carcinoma right breast.,mastectomy with right level 1 and 2 lymph nodes.,received in : formalin fresh procedure : mr mastectomy.laterality : right. total dimensions : medial to lateral 21cm. superficial to deep 4cm. superior to inferior 16cm. skin ellipse : 12 x 6.8 cm. nipple : normal.scar surgical defect : not seen.tumor : single.tumour size : 3.3 x 2.5 x 2 cm greywhite firm. location of tumor : lower outer quadrant. margins of tumor : ill defined. deep margin : 1cm.muscle : absent adjacent breast : fibrofatty. axillary tail : 6 x 6 x 2.5 cm.size of largest node : 2 x 1 x 1 cm cut surface : fatty infiltration.representative sections are submitted.,section shows tumor cells in diffuse sheets and nests. individual tumor cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular or perineural invasion is not identified.,right breast right modified radical mastectomy : invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). tumor is unifocal and is located in the lower outer quadrant. tumor measures 3.3 cm in greatest dimension. lymphovascular invasion is not seen. perineural invasion is not seen. ductal carcinoma in situ is not seen. posterior resection margin is free of tumor. nipple and areola are free of tumor.lymph nodes: twenty seven lymph nodes are identified negative for malignancy(0 27). pathological stage : pt2n0summary: right mrm invasive ductal carcinoma grade 2.nodal metastases 0 27.
MR160012301,two irregular right breast lesion in upper and outer quadrant.,biopsy form right breast lump.,received five grey white linear cores measuring 0.8 to 1 cm.entire tissue processed.,section studied shows linear cores of breast parenchyma with cells arranged in tubules. cells have moderate amount of cytoplasm pleomorphic nuclei with fine granular chromatin and occasional nucleoli. occasional mitotic figures are discerned. stroma shows fibrosis and adjacent hemorrhagic areas.,right breast lump core biopsy:features are suggestive of atypical microglandular adenosis.however a low grade ductal carcinoma cannot be ruled out.suggest excision of the lump for further confirmation.
MR160012306,right breast lump carcinoma.trucut biopsy.,biopsy from right breast lump.,received 4 grey white linear cores measuring 1 to 1.5 cm.entire tissue processed.,sections studied shows breast parenchyma harboring a cellular lesion arranged in sheets and lobules. cells have moderate amount of cytoplasm pleomorphic hyperchromatic nuclei. mitotic figures are discerned. stroma shows fibrosis and inflammatory infiltrate.,right breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160012324,left breast lump carcinoma,biopsy from left breast lump.,received 3 grey white linear cores measuring 1 to 1.2cm.entire tissue processed.,section studied shows breast parenchyma harboring a neoplastic lesion arranged in sheets nests and cords. individual cells have moderate amount of cytoplasm pleomorphic hyperchromatic nuclei. mitotic figures are discerned. stroma shows fibrosis and inflammatory infiltrate.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score 6(3+2+1).
MR160012353,mass in left breast carcinoma breast,biopsy from left breast mass.,received 3 grey white linear cores measuring 1 to 1.2 cm.entire tissue processed.,linear cores of tissue exhibiting a neoplastic lesion arranged in sheets nests and islands consisting of round to oval cells demonstrating mild to moderate atypia and pole eosinophilic cytoplasm amidst desmoplastic stroma and mucinous areas.,biopsy from left breast mass:invasive carcinoma with mucinous and neuroendrocine differentiation. grade 2 tubular formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR160012362,mass in right breast carcinoma breast.,biopsy from right breast.,received 3 grey white linear cores measuring 1 to 1.5 cm.entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged as cords and tubules. the lesional cells have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,infiltrating ductal carcinoma biopsy right breast.grade 2 (7 9)tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR160012405,left breast carcinoma.,left modified radical mastectomy.,received in : formalin fresh time of receipt at lab : time to formalin :procedure : mr mastectomy.laterality : left. total dimensions : medial to lateral 20cm. superficial to deep 5cm. superior to inferior 19cm. skin ellipse : 15x13cm. nipple : normal.scar surgical defect : not seen.tumor : multiple tumor i greywhite relatively well circumscribed lesion measuring 3x2.8x2.5cm located in the lower outer quadrant deep margin is 2cm away.tumor ii relatively greywhite relatively well circumscribed lesion in the upper quadrant measuring 2x2x1cm deep margin is 1cm. margins of tumor : deep margin : muscle : absent adjacent breast : fibrofatty. axillary tail : 5x4x4cm.total number of nodes : 17nodes.size of largest node : 2x1x1cm cut surface : fatty infiltration.,sections from tumor 1 2 show similar morphology. the tumour cells arranged in nests cords tubules and in sheets.the cells exhibit marked pleomorphism with round to oval vesicular nuclei prominent nucleoli and moderate amount of cytoplasm.intervening stroma shows lymphocytic infiltrate desmoplasia fibrosis and necrosis.congested blood vessels are noted.mitotic figures noted.intertumoral fat shows not tumor deposit.,left breast left modified radical mastectomy: invasive ductal carcinoma grade ii.modified br score is 7 9.tubule formation: 2.nuclear pleomorphism: 3mitotic figures: 2.tumor i lower outer quadrant tumor ii upper quadrant.measures largest dimension tumor i 3cm tumor ii 2cm distance between two tumors 1.5cm.ductal carcinoma in situ with comedonecrosis seen.lymphovascular invasion is seen.perineural invasion is not seen.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: seventeen lymph nodes metastasis: nil (0 17) . the show reactive hyperplasia.summary: left mrm invasive ductal carcinoma grade ii.multifocal dcis with comedonecrosis seen.nodal metastases 0 17.
MR160012427,right breast lump carcinoma.,biopsy form right breast.,received multiple grey white linear cores measuring 0.4 to 0.7 cm.entire tissue processed.,linear cores of neoplasm composed of variably cellular spindle cell stroma harboring few benign left like and tubular glandular elements lined by bilayered epithelium.,fibroepithelial lesion biopsy right breast. fibroadenoma. phyllodes.no evidence of malignancy in the cores submitted.
MR160012455,left breast lump carcinoma left breast.,biopsy form left breast.,received 5 grey white linear cores measuring 0.5 to 1.5 cm.entire tissue processed.,section shows cores of tissue infiltrated by tumor cell in cords and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160012466,right breast lump carcinoma.,biopsy from right breast.,received four grey white linear cores measuring 1.2 to 1.5 cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged in glandular pattern. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic. lymphovascular emboli seen.,invasive ductal carcinoma biopsy right breast.
MR160012477,mass in right breast carcinoma breast.,biopsy from right breast mass.,received 3 grey white linear cores measuring 1 to 1.2 cm.entire tissue processed.,section studied shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in sheets cords and trabecular. cells have moderate amount of cytoplasm pleomorphic hyperchromatic nuclei. mitotic activity is discerned. stroma shows fibrosis.,right breast mass core biopsy:invasive ductal carcinoma grade 2. modified br score 6 (3+2+1).
MR160012488,right breast carcinoma with axillary node.,biopsy from right axillary lymphnode.,received 5 grey white linear cores measuring 1 to 1.4 cm.entire tissue processed.,linear cores of lymphoid tissue infiltrated by a neoplasm arranged as islands and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclear conspicuous nucleoli and moderate cytoplasm. the intervening stroma is fibrosis.,metastatic carcinoma biopsy right axillary lymphnode in a known case of carcinoma breast.
MR160012501,left breast carcinoma,a) left breast conservative surgery sentinel lymph nodesb) left breast lumpectomyc) revised base margind) revised inferior margins,a) received 2 lymph nodes largest lymph node measures 2x1x0.5cm cut surface shows fatty infiltrationother lymph node measures 1.5x1x0.5cmb) received skin covered fibrofatty tissue measures 5x3.5x2.5cm skin ellipse measures 4x1cm.cut surface shows grey white lesion measures 2.8x2x1.5cm located at the following distances from the respective margins:superior margin 1.0cminferior margin 0.7cmmedial margin 0.4cmlateral margin 1.5cmdeep margin 0.5cmc)received fibrofatty tissue measures 2.5x2.5x0.5cmd) received fibrofatty tissue measures 3x2.5x0.5cm,a) left breast conservative surgery sentinel lymph nodes : 2 lymph nodes show reactive hyperplasia no metastatic deposits of tumorb) left breast lumpectomy:the section from the tumor shows pleomorphic polyhedral cells with pleomorphic vesicular nucleus with eosinophilic cytoplasm present sheets clumps and groups. invasive ductal carcinomagrade tubule formation 3nuclear pleomorphism 2mitotic figures 2 mbr score 7 9 nuclear grade iiductal carcinoma in situ not presentlymphovascular invasion not presentperineural invasion not presentresected margin:superior margin free of tumorinferior margin free of tumormedial margin free of tumorlateral margin free of tumordeep margin 0.3cm from the tumor c) revised base margin:shows fibrofatty tissue free of tumord) revised inferior margins free of tumor,a) left breast conservative surgery sentinel lymph nodes : 2 nodes no deposits of tumorb) left breast lumpectomy:breast conservative surgery:invasive ductal carcinomanuclear grade iiductal carcinoma in situ not presentlymphovascular invasion not presentperineural invasion not presentall resected margins are free of tumorc) revised base margin:free of tumord) revised inferior margins : free of tumor
MR160012536,carcinoma left breast.,a) wide excision of the lump.b) sentinel lymph nodes.c) revised deep margin.,a) received lumpectomy specimen measuring 8x7x3cmskin ellipse measuring 7x3cm.tumor measuring 2.5x2x2cm.cut surface : greywhite.located at the following distances from respective margins: superior margin 2cm.inferior margin 4cm.medial margin 1.8cm.lateral margin 2cm.deep margin 0.5cm.b) received single fibrofatty tissue measuring 2.5x1.5x1.2cm.isolated 3 lymph nodes.sentinel lymph nodeds measuring 1x0.5x0.5cm.c) received soft tissue bit measuring 5.5x3x1cm one side inked.,a) sections from tumor show breast parenchyma infiltrated by a neoplasm arranged as clusters and islands.the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous ncucleoli and moderate cytoplasm.the intervening stroma shows dense lymphocytic inflammatory cell infiltrate.nipple and areola : free of tumor.b) 3 sentinel lymph nodes isolated are free of tumor.c) section shows fibrofatty tissue which is free of tumor.,a) invasive ductal carcinoma left breast.grade 2 mbr score 7 9 tubule formation:3nuclear pleomorphism: 2mitotic figures: 2.tumor size:2.5x2x2cm.no lymphovascular invasion seen.no perineural invasion seen.moderate intratumoral lymphocytic response is seen.b) 3 sentinel lymph nodes isolated are negative for malignancy.c) revised deep margin : free of tumor.
MR160012544,left breast suspicious area under evaluation,left breast excision biopsy,fresh tissue received : yesnumber of specimens received : 1 laterality : left procedure :specimen orientation : superior (single white) inferior (single black) medial(double white) lateral (double black) deep inked triple white superficialspecimen size : 3.5x2.5x1.5cm skin : absent nipple : absent lesion(s) : presentnumber of macroscopically visible lesions : 1 lesion description : grey white lesion dimensions : 1.8 x 1 x 0.9 cm distance of lesion from margins : superior 0.4cm inferior 0.2cm medial 1.5 cm lateral 0.1 cm deep 0.2 cm superficial 0.9cmdistance of lesion to nearest margin : 0.1cm lateral margin,multiple sections from the breast parenchyma show a lesion arranged in solid nests and papillary pattern lined by columnar cells with round to oval vesicular nuclei dispersed fine chromatin and moderate eosinophilic cytoplasm. areas of ductal carcinoma in situ seen with solid and cribriform pattern. adjacent breast shows cystic change,left breast excision biopsy :suggest of ductal carcinoma in situ of solid and cribriform pattern with intermediate nuclear grade. estimated size of the dcis is 0.4 cm. all resected margins are free of tumor. adjacent breast tissue shows papillary lesionsuggest ihc.
MR160012548,multiple liver lesions hcc mets.,biopsy from liver lesion.,received 4 grey white to grey brown linear cores measuring 1 to 1.2 cm.entire tissue processed.,linear cores of tissue exhibiting nests islands and vague glandular configuration of round to cuboidal cells with vesicular nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm amidst desmoplastic stroma and extensive areas of necrosis.,biopsy from liver lesion:positive for malignancy.suggestive of metastatic carcinoma in know case of carcinoma breast.
MR160012583,right breast lump carcinoma breast,biopsy of right breast lump,received multiple grey white linear cores measures 1 to 1.3cm. entire tissue is processed,linear cores of breast tissue infiltrated by a neoplasm arranged as cords trabeculae and nests. the neoplastic cells have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic,invasive carcinoma with lobular features biopsy of right breastgrade 2 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR160012598,carcinoma right breast post lumpectomy status.,right modified radical mastectomy.,received in : formalin.procedure : mrm post lumpectomy.laterality : right.total dimensions : medial to lateral 14cm. superficial to deep 3.5cm. superior to inferior 13cm.skin ellipse : 10x8cm.nipple areola : normal.scar measures 4cm present 3cm above nipple in upper outer quadrant.grey white lesion : single.grey white lesion : 1.5x1.2x1.2cm.margins of tumor : well circumscribed.deep margin : 1.3cm.muscle : absent.adjacent breast : fibrofatty tissue.axillary tail : 8x5x3cm.an illdefined fibrocysic area noted behind 5 lack 1x0.5x0.5cm.distance from deep 2cm.total number of nodes : 19.size of largest node : 1.5x1.5x0.8cm. cut surface show fatty infiltration.,sections show breast parenchyma harboring an infiltrative lesion arranged in nests sheets lobules comprising of round to oval moderately pleomorphic vesicular nuclei with prominent nucleoli and moderate cytoplasm. areas of solid dcis and necrosis seen. adjacent stroma shows lymphocytic infiltrate. mitotic activity is brisk.,histopathologic examination:right breast invasive ductal carcinoma grade ii. residual tumor status post lumpectomy.modified br score is :7 9tubule formation : 2nuclear pleomorphism :2mitotic figures :3tumor measures 1.5cm in greatest dimension and is located in the retroareolar quadrant.ductal carcinoma in situ present with comedonecrosis .lymphovascular invasion identified.perineural invasion not identified.posterior resection margin is free of tumor.nipple and areola is free of tumor.lymph nodes : 20 lymph nodes dissected all are free of metastasis: ( 0 20).summary: right mrm invasive ductal carcinoma grade iiresidual tumor status post lumpectomy.nodal metastases nil 0 20.
MR160012608,bilateral breast mass,a) biopsy of left breast massb) biopsy of right breast mass,a) received multiple grey white to grey yellow linear cores measures 1 to 1.2cm. entire tissue is processedb) received multiple grey white linear cores measures 1 to 1.4cm. entire tissue is processed.,section from both breast mass shows linear cores of breast parenchyma exhibiting nests and cords of round to oval neoplastic cells demonstrating moderate nuclear pleomorphism and eosinophilic cytoplasm amidst a desmoplastic stroma.,a amp b) right and left breast core biopsy : invasive ductal carcinoma grade 2. modified bloom richardson score 7(3+2+2).
MR160012640,mass in right breast carcinoma breast.,biopsy right breast.,received 4 grey white linear cores measuring 0.8 to 1.0 cm.entire tissue processed.,linear cores of breast tissue infiltrated by a sheets. the neoplastic cells exhibit moderate nuclear pleomorphic have hyperchromatic to vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is desmoplastic.,invasive ductal carcinoma biopsy right breast.grade 3(8 9)tubule formation 3nuclear pleomorphism 2mitotic figures 3 8 9
MR160012644,mass in left breast carcinoma breast.,biopsy from left breast.,received 3 grey white linear cores measuring 0.6 to 1.1 cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords and tubules and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,invasive ductal carcinoma biopsy from left breast.grade 2(7 9)tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR160012663,right breast masscarcinoma breast,biopsy of right breast mass,received multiple grey white to grey brown cores measures 0.6 to 1cm.,fragmented linear cores of breast parenchyma exhibiting papillary proliferation of cells lined by columnar cells with focal stratification and apocrine change admixed with few areas showing mucinous material.,biopsy from right breast mass:features are suggestive of papillary neoplasm.suggest excision of lump and ihc for further confirmation.
MR160012675,a) lumpectomy wide excsion frozen specimen.b) left axillary clearance.,a) received lumpectomy specimen measuring 8x5x5cm. skin ellipse measures 6x2cm with scar measuring 3cm.cut surface shows greywhite firm tumor area measuring 1x1x0.5cm located at the following distances from respective margins: superior margin 1cm.inferior margin 1cm.lateral margin 3cm.medial margin 4cm.deep margin 1cm.b) received multiple fibrofatty tissue altogether measuring 7x6x4cm.largest lymph node measuring 1x0.5cm. cut surface is unremarkable.,a) lumpectomy wide excsion frozen,tumor bed : residual viable tumor present.tumor measuring 1x1x0.5cm with invasive ductal carcinoma.tubular formation : 3nuclear pleomorphism : 1mitotic figures : 2 6 9 nuclear grade ii.dcis : not present.lymphovascular invasion is present.perineural invasion is present.resected margins: superior margin free of tumor.inferior margin free of tumor.lateral margin free of tumor.medial margin free of tumor.deep margin free of tumor.axillary clearance :12 nodes show metastatic deposits of viable tumor out of 17 nodes. perinodal spread present.,lumpectomy wide excision:residual viable tumor present measuring 1x1x0.5cm with invasive ductal carcinoma.nuclear grade ii.dcis : not present.lymphovascular invasion is present.perineural invasion is present.all resected margins are free of tumor.b) left axillary clearance:12 nodes show metastatic deposits of viable tumor out of 17 nodes. perinodal spread present.
MR160012715,left lung nodule.carcinoma lung metastatic lesion carcinoma breast.,biopsy from left lung mass.,received 3 grey white linear cores measuring 0.5 to 1.2cm. issued to tata mc: 2 linear cores of tissue measuring 1.5cm. handed over to bearer name.,linear cores of lung parenchyma show invasive sheets and nests of dysplastic oval to polygonal cells with abundant eosinophilic cytoplasm. the cells exhibit moderate nuclear pleomorphic. intervening stroma is desmoplastic and shows moderate dense lymphoplasmic infiltrate.,malignant lesion favor metastases in a known case of carcinoma breast .
MR160012716,mass in left breast carcinoma breast.,biopsy from left breast.,received 2 grey white linear cores measuring 1 to 1.2 cm.entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as sheets and cords. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm.,poorly differentiated malignancy favoring:invasive carcinoma left breast.grade 2(6 9)tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR160012727,mass in right breast carcinoma breast.,biopsy from right breast.,received 3 grey white linear cores measuring 0.6 to 1.2 cm.entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as tubule and clusters. the neoplastic cell exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is desmoplastic.,invasive ductal carcinoma biopsy right breast.grade 2(6 9).tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR160012741,mass in left breast carcinoma breast,biopsy of left breast mass,received multiple grey white to linear cores measures 1 to 1.4cm. entire tissue is processed.,sections studied shows fibrocollagenous tissue harboring a neoplastic lesion arranged in sheets and cords. individual cells have moderate amount of cytoplasm pleomorphic hyperchromatic nuclei. mitotic activity is discerned. adjacent stroma shows fibrosis.,left breast mass core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160012750,lump in right breast,a) lumpectomy with right breast breast conservative surgeryb) axillary level i and ii ymph nodesc) level iii lymph nodes,a) lumpectomy with right breast breast conservative surgery:received fibrofatty tissue measures 6.5x5.5x2cm skin ellipse measures 3x0.7cmcut surface shows illdefined grey white tumor measures 0.5x0.5x0.5cmlocated at the following distances from the respective margins:superior margin 4cminferior margin 1.4cmmedial margin 3cmlateral margin 1cmdeep margin 1cmb) axillary level i and ii lymph nodes:received fibrofatty tissue measures 6x5.5x2.5cm largest lymph node measures 2x1.5x1cmcut surface shows grey brown fatty infiltrationc) level iii lymph nodes:received fibrofatty tissue measures 1x1x0.5cm identified one lymph node,a) lumpectomy with right breast breast conservative surgery:tumor bed: small focus of viable tumor present consisting of small clumps of pleomorphic cells with hyperchromatic nucleus with eosinophilic cytoplasm. surrounding the tumor dense lymphocytic infiltration is present tumor is measuring 0.5x0.5cm. surrounding the tumor dense fibrosis lymphocytic infiltration atrophic ducts and surrounding ducts show adenosis and epithelial hyperplasia.lymphovascular invasion not presentresected margins : superior margin free of tumorinferior margin free of tumormedial margin free of tumorlateral margin free of tumordeep margin free of tumorb) axillary level i and ii lymph nodes:11 lymph nodes no deposits of tumorc) level iii lymph nodes:one node no deposits of tumor,a) lumpectomy with right breast breast conservative surgery la small focus of viable tumor presentinvasive ductal carcinoma measures 0.5x0.5cmdense lymphocytic infiltration and fibrosis is present surrounding clumps of tumor cellsall resected margins are free of tumorb) axillary level i and ii lymph nodes:11 nodes no deposits of tumor presentc) level iii lymph nodes:one node no deposits of tumor
MR160012770,mass in left breast carcinoma breast.,biopsy from breast.,received multiple fragmented linear cores measuring 0.4 to 0.8 cm.entire tissue processed.,section show fragments of tissue showing desmoplasia with few scattered cells. loss pf crush artifact seen.,breast trucut biopsy:scattered atypical cells are seen.inadequate for opinion.suggest repeat biopsy.
MR160012777,liver lesion metastasis.,biopsy from liver lesion.,received five grey white linear cores measures 2 to 2.5 cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in tubules acini and in cords. the cells have round hyperchromatic nuclei and moderate cytoplasm.,biopsy from liver lesion. suggestive of metastatic carcinoma in a known and treated case of carcinoma right breast.
MR160012794,left breast mass carcinoma breast.,biopsy from left breast mass.,received four grey white linear cores measuring 0.8 to 1.2 cm.entire tissue processed.,section from breast shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160012807,mass in left breast carcinoma breast.,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 0.8 to 1 cm.entire tissue processed.,section show linear cores of tissue with neoplastic lesion arranged in sheets. individual cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma show fibrosis. large areas of necrosis noted.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160012810,mass in left breast carcinoma breast,biopsy of left breast,received multiple grey white linear cores measures 0.8 to 1cm. entire tissue is processed,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in nests sheets and cords in tubule formation. the cells are pleomorphic with round to oval vesicular nuclei and prominent nucleoli. adjacent stroma shows desmoplasia and elastosis. areas of necrosis seen,left breast biopsyinvasive ductal carcinoma grade 2mbr score tubule formation 3nuclear pleomorphism 2mitotic figures 2 areas of necrosis seen
MR160012837,mass in right breast carcinoma breast.,biopsy from right breast.,received multiple tiny grey white soft tissue bits altogether measuring 0.3x0.2x0.2 cm.entire tissue processed.,section shows fragments of breast tissue infiltrated by a lesion arranged in nests oval cords of small cells with uniform round to oval hyperchromatic nuclei and correlate amount of eosinophilic cytoplasm. admixed are mucinous areas. stroma shows fibrocollagenous change.,right breast biopsy:invasive carcinoma with mucinous features. nuclear grade 1.
MR160012844,mass in left breast carcinoma breast.,biopsy form left breast.,received three grey white linear cores measuring 0.8 to 1 cm.entire tissue processed.,section shows cores of breast parenchyma harboring a lesion arranged in trabecular nests and cords comprising of atypical cells with mild to moderately pleomorphic hyperchromatic nuclei and scanty to moderate eosinophilic cytoplasm. mitotic figures discerned. stroma shows extensive fibrosis and hyalinisation.,left breast biopsy:invasive ductal carcinoma grade : 2.modified br score 6 9.tubular formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR160012846,carcinoma right buccal mucosa,a) right composite resectionb) right neck dissection,a) laterality : rightmeasurements of bone (length ) : 6cmmucosa :2.8x3.5cmsalivary gland : absent skin flap shows nodular elevation: 5x4.3cmteeth (number) : 5site of tumor : right buccal mucosatumor size : 2.7x1.7x3.2cmappearance : ulcerativeresected margins orientated :yesdistance from margins :anterior margin : 1cmposterior margin : 1.2cmsuperior margin : 1cminferior margin : 1.5cmdeep margin : 0.2cmb) received fibrofatty tissue measures 5x4x3cm skin ellipse measures 2.5x2x1cm,a) sections show infiltrative lesion arranged in sheets islands nests lobules pleomorphic vesicular nuclei prominent nucleoli and moderate cytoplasm. mitotic figures discerned. adjacent stroma shows desmoplasia. area of necrosis and myxoid areas noted. overlying skin appears to be normal.lymphovascular invasion and perineural invasion not identifiedanterior posterior superior inferior margins are free of tumor skin margin is free of tumorone node dissected shows tumorb) identified 4 lymph nodes free of tumorsalivary gland free of tumor,a) moderately differentiated squamous cell carcinoma right breast mucosalarger tumor dimension measures 2.7cmlymphovascular invasion not identifiedperineural invasion not identifiedoverlying skin is free of tumorall resected margins are free of tumor.identified one lymph node involved by tumor(1 1)no perinodal spread seenb) identified 4 lymph nodes free of tumorthey show reactive hyperplasia (0 4)salivary gland is free of tumor
MR160012847,right breast mass to riule out carcinoma.,biopsy from right breast mass.,received five grey white linear cores measuring 0.8 to 1 cm.entire tissue processed.,linear cores of breast tissue harboring a benign biphasic tumor with epithelial and stromal components. compressed glands lined by bilayered epithelium are seen. foci of usual ductal hyperplasia noted.,fibroepithelial lesion fibroadenoma.
MR160012898,known case of carcinoma left breast.,biopsy from chest wall lesion.,received 2 skin covered soft tissue bits measures 2.5x1.5x0.4cm.entire tissue processed.smaller measures 2x0.4x0.3cm. entire tissue processed.,section shows skin with subcutaneous tissue harboring an invasive neoplasm in the fibrosi and subcutaneous tissue predominantly in nests tubules and cords. the cells show moderate nuclear pleomorphism increased mitosis and moderate eosinophilic vacuolated cytoplasm. the tumor involves the epidermis in form of pagetoid spread lymphatic emboli seen.,biopsy from chest wall lesion:recurrent invasive carcinoma( nst) in a known case of carcinoma breast.
MR160012912,mass in left breast carcinoma breast.,biopsy from left breast.,received five grey white linear cores measuring 0.7 to 1 cm.entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as sheets cords and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. areas of necrosis seen.,infiltrating ductal carcinoma biopsy left breast.grade 2(7 9).tubular formation 3nuclear pleomorphic 2mitotic figures 2 7 9
MR160012918,mass in right breast carcinoma breast,biopsy from right breast mass,received multiple grey white linear cores measures 1 to 1.2cm,linear cores of breast tissue infiltrated by a neoplasm arranged as cords trabeculae and clusters. the neoplastic cells have hyperchromatic nuclei and moderate cytoplasm. crush artifacts seen,infiltrating ductal carcinoma biopsy of right breastgrade 2 (7 9)(tubule formation 3 nuclear pleomorphism 2 mitotic figures 2)
MR160012949,mass in left breast carcinoma breast.,biopsy from left breast mass.,received three grey white linear cores measuring 0.8 to 1.2 cm.entire tissue processed.,section from breast shows tumor cells in diffuse sheets and nests. individual tumor cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160012976,left breast mass infection. carcinoma breast.,biopsy from left breast mass.,received 5 very ting linear fragmented cores measuring 0.2 to 0.3 cm.entire tissue processed.,section shows cores of breast tissue infiltrated by inflammatory aggregates comprising of plasma cells lymphocytes neutrophils. areas of hyalinisation sees along with scattered fibroblasts and histiocytes.,left breast mass biopsy:acute on chronic inflammation.no evidence of malignancy in the sections studied.
MR160012977,mass in right breast carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measuring 0.8 to 1.2 cm.entire tissue processed.,linear cores of lowest parenchyma infiltrated by a neoplasm arranged as islands and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm lymphovascular emboli seen.,infiltrating ductal carcinoma biopsy right breast:grade 2(6 9).tubular formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR160012987,mass in right breast carcinoma breast.,biopsy from right breast.,received 3 grey white linear cores measuring 0.8 to 1 cm.entire tissue processed.,section studied shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in sheets cords and tubules. cells have moderate amount of cytoplasm pleomorphic hyperchromatic nuclei and inconspicuous nucleoli. mitotic activity is seen,infiltrating ductal carcinoma biopsy from right breast:grade 2 (7 9)tubule formation 3nuclear pleomorphism 2mitotic figures 2
MR160013038,mass in left breast carcinoma breast.,biopsy from left breast.,received three grey white to grey brown linear cores measuring 1 to 1.2 cm.entire tissue processed.,section shows cores of breast parenchyma harboring an infiltrative lesion arranged in nests and sheets. cells exhibit moderate to marked nuclear pleomorphism vesicular nuclei with irregular nuclear membrance prominent nucleoli and moderate eosinophilic to clear cytoplasm. mitotic figures discerned. areas of necrosis noted.,biopsy left breast:invasive ductal carcinoma grade iii.modified br score 8 9.tubular formation 3nuclear pleomorphism 3mitotic figures 2 8 9
MR160013082,carcinoma right breast post op recurrence,biopsy from right breast.,received 3 grey white linear cores measure 0.2 to 0.3 entire tissue processed.,linear cores of fibrous and fatty tissue harboring a few tiny capillaries.,biopsy from right breast:only fibrous tissue seen in the biopsy submitted.
MR160013089,irregular spiculated mass in left breast (3 0 clock) carcinoma left breast.,a) biopsy left breast.,received four grey white linear cores measuring 1 to 1.2 cm.entire tissue processed.,a) section studied shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords trabeculae and tubules. the cells have moderate amount of cytoplasm pleomorphic hyperchromatic nuclei. mitotic activity is discerned. stroma shows elastosis. foci of calcification seen.,a) invasive ductal carcinoma biopsy left breast.grade 2(6 9).tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR160013100,right breast lump carcinoma.,biopsy from right breast lump.,received four grey white to grey brown linear cores measuring 0.7 to 1.2 cm.entire tissue processed.,section studied shows linear cores of breast parenchyma harboring a cellular lesion arranged in sheets cords and trabeculae. the cells have moderate amount of cytoplasm pleomorphic hyperchromatic nuclei. mitotic figures are discerned. stroma shows elastosis.,invasive ductal carcinoma biopsy from right breast lump.grade 2 modified br score 6.tubular formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR160013111,right breast lump carcinoma.,biopsy from right breast lump.,received four grey white to grey brown linear cores measuring 0.7 to 1 cm.entire tissue processed.,section studied shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords and trabeculae. the cells have moderate amount of cytoplasm pleomorphic hyperchromatic nuclei. mitotic figures are discerned. stroma shows fibrosis.,invasive ductal carcinoma biopsy from right breast lump.modified br score grade 2(7 9).tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR160013124,right breast lump carcinoma.,biospy from right breast lump.,received 3 greybrown linear cores measuring 0.5 to 0.6cm. entire tissue processed.,linear cores of predominantly necrotic tissue harboring occasional atypical cells. one of the cores show fibroblastic proliferation and mixed inflammatory infiltrate composed of neutrophils lymphocytes and plasma cells.,occasional atypical cells seen.in view of predominantly necrotic tissue kindly repeat biopsy from viable tumor area.
MR160013143,mass in left breast carcinoma breast.,left breast core biopsy.,received three grey white to grey brown linear cores measuring 1 to 1.3cm. entire tissue processed.,section shows breast tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160013166,left breast solid cystic mass carcinoma.left supraclavicular multiple lymph nodes metastasis.,biopsy from left breast lesion.,received four grey white to grey brown linear cores measuring 1 to 1.3cm.entire tissue processed.,linear cores of tissue exhibiting a neoplastic lesion arranged in sheets nests and islands consisting of polygonal to oval cells demonstrating moderate nuclear pleomorphism and eosinophilic cytoplasm. there are small cores of keratinization. intervening areas show desmoplastic stroma. small fragment of skin is also noted.,biopsy from left breast lesion :high grade carcinoma. primary in breast.
MR160013173,carcinoma right breast post op.,sternal lesion biopsy.,received four grey white to grey brown linear cores measuring 1.2 to 1.4cm. entire tissue processed.,section shows fibrocollagenous tissue infiltrated by tumor cells in nests and cords. individual tumor cells have round to oval nuclei and moderate amount of eosinophilic cytoplasm.,sternal lesion biopsy :suggestive of recurrent deposit of carcinoma in known and treated case of carcinoma right breast.
MR160013194,mass in right breast carcinoma breast.,right breast core biopsy.,received four grey white to grey brown linear cores measuring 1 to 1.2cm. entire tissue processed.,section show linear cores of tissue with a neoplastic lesion arranged in cords and sheets. individual cells have pleomorphic round to oval hyperchromatic nuclei inconspicuous nucleoli and moderate amount of cytoplasm. stroma show desmoplasia and hyalinisation ductal carcinoma in situ solid and comedo necrosis type is seen.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). ductal carcinoma in situ of solid and comedo pattern with intermediate nuclear grade.
MR160013207,left breast mass,biopsy of left breast,received multiple grey white to grey brown linear cores measures 0.8 to 1.2cm. entire tissue is processed,section shows linear trucut cores of breast parenchyma with sheets clusters and cords of large atypical cells with hyperchromatic nuclei few show prominent nucleoli moderate to abundant cytoplasm. frequent mitotic figures discerned. stroma shows desmoplastic response,invasive ductal carcinoma nos grade 3tubule formation 3nuclear pleomorphism 3mitotic figures 2 8 9
MR160013285,right breast carcinoma,a) right breast lumpectomyb) right axillary clearance,a) received fibrofatty tissue with elliptical piece of skin measures 4.5x3.5x2.5cm skinellipse measures 2x1cm cut surface shows grossly no tumor seen shows fibrotic areameasures 1x1cm.located at the following distances from the respective margins:superior margin 2cminferior margin 1cmmedial margin 1cmlateral margin 2cmdeep margin 0.5cmb) axillary lymph nodes:received fibrofatty tissue measures 8x7x2cm largest lymph node measures 2x1.8x0.8cm cut surface shows grey white,a) right breast lumpectomy:lumpectomy bed:the section shows fibrosis with atrophic ducts and lymphocytes and histiocytic cells.surrounding breast parenchyma ducts show adenosisthere is no evidence of residual viable tumor presentresected margins:superior margin free of tumorinferior margin free of tumormedial margin free of tumorlateral margin free of tumordeep margin free of tumorb) right axillary clearanceone node shows metastatic deposits of invasive ductal carcinoma out of 19 nodesperinodal spread not presentthe biggest node is 2x1.8cm,a) right breast lumpectomy:post lumpectomy post nactno residual viable tumor presentall resected margins are free of tumorb) right axillary clearance:one node shows metastatic deposits of invasive ductal carcinoma out of 19 nodesperinodal spread present
MR160013296,carcinoma right breast,a) sentinel lymph node right axillab) right mastectomy,a) received fibrofatty tissue measures 3.5x2x1cm largest lymph node measures 1.5x1x0.5cm.cut surface shows fatty infiltration. total isolated 4b) received in : formalin.laterality : right total dimensions : medial lateral : 20cm. superficial deep : 5cm. superior inferior : 19cm.skin ellipse : 14.5x5cm.nipple : normal.scar surgical defect : absenttumor : single tumor size : 2 cm (largest dimension ) 2x1.5cm.location of tumor : lower outer quadrantmargins of tumor : ill defined.deep margin :1.5cm.muscle : absent.adjacent breast : fibrofatty.axillary tail : absent,b) multiple section shows breast parenchyma harboring a cellular neoplastic lesion arranged in tubules and sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. desmoplastic stroma shows areas of hemorrhage and necrosis. mitotic figures are discerned. ductal carcinoma in situ solid and comedonecrosis is seen. lymphovascular invasion is not identified.a) sentinel node .right axilla four nodes isolated are free of tumor (0 4),b)right breast invasive ductal carcinoma grade 2modified br score is 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2ductal carcinoma in situ with comedonecrosis identified solid type(constitiutes 40 of the total tumor volume) invasive component is approximately 1.2 cm lymphovascular invasion is not identifiedperineural invasion not identifiedposterior resection margin is free of tumornipple and areola is unremarkablepathological stage pt1ca) sentinel node .right axilla four nodes isolated are free of tumor (0 4)
MR160013301,mass ion right breast carcinoma breast,biopsy from right breast mass,received multiple grey white to grey brown linear cores measures 0.9 to 1.2cm. entire tissue is processed.,section shows linear cores of tissue with a neoplastic lesion arranged in sheets. individual cells have pleomorphic round to oval hyperchromatic nuclei inconspicuous nucleoli and moderate amount of cytoplasm. stroma shows desmoplasia hyalinisation and inflammatory infiltrate consisting of lymphocytes few plasma cells. areas of necrosis noted. mitotic figures discerned.,right breast core biopsy:invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+2+3)
MR160013304,mass in left breast carcinoma breast,biopsy from left breast mass,received tiny grey white to grey brown linear cores measures 1.2 to 1.4 cm. entire tissue is processed,section show linear cores of tissue with necrosis and fibrosis with few sheets of atypical cells having round to oval hyperchromatic nuclei and moderate amount of cytoplasm. scattered inflammatory cells seen.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score 6(3+2+1).
MR160013306,mass in left breast carcinoma breast.,biopsy from left breast mass.,received two grey white to grey brown linear cores measuring 0.8 to 1.2 cm.entire tissue processed.,sections from the linear cores submitted shows a lesion arranged in tubules cords and aggregates. the neoplastic cells show vesicular nucleus with moderate amount of cytoplasm. atypical mitotic figures discerned. no lymphovascular emboli or perineural invasion noted.,invasive ductal carcinoma grade ii.mbr score 7 9
MR160013314,mass in left breast carcinoma breast.,biopsy from left breast.,received multiple grey white to grey brown linear cores measuring 0.9 to 1.2cm.,section shows linear cores of breast parenchyma harboring an infiltrating cellular neoplastic lesion arranged in sheets cords and tubules.the cells are ovoid having moderate amount of cytoplasm hyperchromatic pleomorphic nucleus with prominent nucleoli.atypical mitotic figures are discerned.stroma shows desmoplasia with areas of hemorrhage necrosis and chronic inflammatory infiltrate.ductal carcinoma in situ of solid and comedonecrosis type is noted.,left breast mass biopsy:invasive ductal carcinoma grade 2mbr score is 7 9.tubule formation:3nuclear pleomorphism:2mitoses:2areas of necrosis seen.
MR160013327,mass in right breast carcinoma breast,biopsy from right breast,received four grey white to grey brown linear cores measures 0.5 to 0.7cm.,sections studied shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in tubules sheets and cords. the cells have moderate amount of cytoplasm pleomorphic hyperchromatic nuclei and inconspicuous nucleoli. stroma shows fibrosis and congested blood vessels.,invasive ductal carcinoma grade 2 biopsy from right breast mass:mbr score 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1
MR160013329,metastatic carcinoma breast right with skin ulceration,right toilet mastectomy,received in : formalinprocedure : mastectomy laterality : right total dimensions : medial lateral superficial deep superior inferior skin ellipse : 19x17cm nipple : retracted scar surgical defect : skin ellipse shows a ulceration in the lower inner quadrant measures 6.5x3cm corresponding to the underlying tumor located 0.5cm medial to the nipple and areola tumor : single tumour size : 11x7x5cm. location of tumor : upper inner quadrant and lower inner quadrant margins of tumor : ill defined deep margin : 2cm muscle : present measures 2x1cm adjacent breast : fibrofatty axillary tail : 8x6x3cmsize of largest node : largest matted lymph node measures 4x2x1cm cut surface is grey white tumor deposit,sections from tumor show breast parenchyma infiltrated by a neoplasm arranged as tubules clusters and islands. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm.lymphovascular emboli seen. overlying skin is ulcerated and infiltrated by tumor.nipple and areola free of tumor. deep margin free of tumor. 5 out of 6 right axillary lymph nodes isolated show metastatic deposits of tumor. perinodal spread is seen.,right breast right modified radical mastectomy: invasive ductal carcinoma grade i. modified br score is 5 9.tubule formation: 2nuclear pleomorphism: 2 mitotic figures: 1tumor measures 6.5 cm in greatest dimension and is located in the lower inner quadrant. ductal carcinoma in situ solid(small volume) lymphovascular invasion seenperineural invasion not seenposterior resection margin is free of tumornipple and areola is free of tumor. perinodal spread is seen.lymph nodes: 5 6 lymph nodes metastasis: 5 lymph nodes(5 6) . perinodal spread is seen.summary:right mrm infiltrating ductal carcinoma grade inodal metastases 5 6perinodal spread is seen.
MR160013379,mass in left breast carcinoma breast,biopsy from left breast,received multiple grey white to grey brown linear cores measures 0.4 to 0.6cm. entire tissue is processed.,section shows breast parenchyma harboring a lesion with cells arranged in papillary cribriform pattern and also in sheets. cells have scanty to moderate cytoplasm with round uniform hyperchromatic nuclei.adjacent stroma shows lymphocytic infiltration,biopsy from left breast mass:suggestive of papillary neoplasm.requires into to excision with margins for conclusive opinion
MR160013380,mass in left breast carcinoma breast,biopsy from left breast,received multiple grey white to grey brown linear cores measures 0.5 to 1cm .entire tissue is processed,section from the linear cores show tumor cells arranged in cords nests and sheets. occasional tubule formation noted. cells are pleomorphic with round to oval hyperchromatic nuclei and prominent nucleoli. sheets of lymphocytes seen infiltrating the adjacent stroma,left breast mass biopsy:suggestive of infiltrating ductal carcinoma with dense inflammationmbr score 7
MR160013391,dilated ducts with intraductal mass in left breast papillary carcinoma of left breast,biopsy from left breast mass,received multiple grey white to grey brown linear bits measures 0.3 to 0.5cm. entire tissue is processed.,sections from the core biopsy from the left breast mass predominantly shows benign breast parenchyma with ducts and stroma. there is a solitary fragmentary focus showing cells with stratification hyperchromasia and pleomorphism.,solitary fragmentary focus of atypical cells tissue inadequate for definitive opinionneeds intoto excision for catergorization.
MR160013395,mass in left breast carcinoma breast,biopsy from left breast mass,received multiple grey white to grey brown linear cores measures 0.5 to 1cm. entire tissue is processed,section shows breast parenchyma harboring a lesion with cells arranged in cribriform pattern. cells have moderate to scanty cytoplasm with round to oval hyperchromatic nuclei and inconspicuous nucleoli. foci of sheets of tumor cells seen. areas of hemorrhage and necrosis seen. ductal carcinoma in situ component seen with comedonecrosis of intermediate nuclear grade,left breast mass biopsy fragmentary biopsy with ductal carcinoma in situ and comedonecrosis nuclear grade 2invasion cannot be commented upon due to fragmentary nature of the biopsy
MR160013404,left neck node fnac metastatic adenocarcinoma primary,biopsy from neck node,received multiple grey white to grey brown linear cores measures 0.8 to 1cm.entire tissue is processed,linear cores of tissue infiltrated by a neoplastic lesion arranged in sheets nests and islands consisting ofround to oval cells demonstrating moderate nuclear pleomorphism and eosinophilic cytoplasm amidst a desmoplasticstroma,biopsy from neck node:metastatic carcinomasuggest ihcplease look for primary in breast lung ovary
MR160013409,lump in right breast,right breast lumpectomy,received 2 nodular masses largest measures 3.5x2.5x1.5cm cut surface shows grey white are measures 2x1.3x0.7cm.smaller measures 1.8x1.5x0.7cm cut surface shows grey white area measures 0.5x0.5x0.3cm.distance from the ink margin is 0.1cm,sections reveal breast parenchyma exhibiting a neoplastic lesion arranged in cords nests and vague tubular configuration infiltrating in between normal ducts. the lesional cells harbor vesicular nuclei inconspicuous nucleoliand moderate amount of eosinophilic cytoplasm.,right breast lumpectomy:2 nodulesinvasive ductal carcinoma grade iitubule formation 3nuclear pleomorphism 2mitotic figures 1nodule 1 tumor measures 2x1.3x0.7 distance from the closest inked margin is 0.2cmnodule 2 tumor measures 0.5x0.5x0.3cm distance from the closest inked margin is 0.1cmlymphovascular invasion and perineural invasion are not identified
MR160013461,right breast lump carcinoma.,right breast biopsy.,received four grey white to grey brown linear cores measuring 0.8 to 1cm. entire tissue processed.,section shows linear cores of tissue harboring a neoplastic lesion arranged in sheets and an papillary clusters cells having normal to oval pleomorphic hyperchromatic nuclei with scant cytoplasm. adjacent stroma shows dismoplasia. few foci show in situ papillary type. mitotic figures discerned.,right breast biopsy :invasive carcinoma nuclear grade ii.suggestive of papillary differentiation .foci of ductal carcinoma in situ seen.
MR160013464,left breast lump carcinoma.,biopsy from left breast lump.,received five grey white to grey brown linear cores measuring 1 to 1.3cm. entire tissue processed.,linear cores of tissue infiltrated by sheets and nests of round to oval neoplastic cells demonstrating moderate nuclear pleomorphism and brisk mitotic activity. intervening fibrocollagenous stroma show aggregates lymphocytes.,biopsy from left breast lump :invasive ductal carcinoma grade iii.modified br score is 8 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR160013469,mass in left breast carcinoma breast.,left breast mass biopsy :,received three grey white to grey brown linear cores measuring 0.7 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in sheets clusters. the cells exhibit marked nuclear pleomorphism with hyperchromic nuclei and moderate cytoplasm. adjacent area shows necrosis. desmoplasa seen. brisk mitotic activity seen. areas of necrosis seen.,left breast mass biopsy :invasive ductal carcinoma.modified br score is 8 9. grade iiitubular formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9 areas of necrosis seen.
MR160013474,mass in left breast carcinoma breast.,biopsy left breast mass.,received four grey white to grey brown linear cores measuring 0.8 to 1cm. entire tissue processed.,section shows lesion cores of breast parenchyma harboring a neoplastic lesion arranged in nests clusters and tubules. the cells exhibit moderate nuclear pleomorphism with hyperchromatic nuclei and scant cytoplasm. mitotic figures are discerned. adjacent stroma shows desmoplasia and elastosis.,left breast mass :suggestive of invasive ductal carcinoma.modified br score is 6 9. grade ii.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160013484,mass in left breast carcinoma breast,biopsy from left breast mass,received multiple grey white to grey brown linear cores measures 1 to 1.2cm.entire tissue is processed.,section show linear cores of tissue with neoplastic lesion arranged in cords and sheets. individual cells have pleomorphic round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows hyalinisation. ductal carcinoma in situ with comedonecrosis noted.,left breast core biopsyinvasive ductal carcinoma grade iimbr score 6tubule formation 3 nuclear pleomorphism 2mitotic activity 1ductal carcinoma in situ with comedonecrosis
MR160013546,left breast lump carcinoma.,left breast biopsy.,received three grey white to grey brown linear cores measuring 0.7 to 1cm. entire tissue processed.,sections shows linear cores of beast parenchyma harboring a neoplastic lesion arranged in sheets and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma shows desmoplasia with chronic inflammatory infiltrates. areas of hemorrhage and necrosis seen.,left breast biopsy :invasive ductal carcinoma grade 2.modified br score is 7 9tubular formation : 3.nuclear pleomorphism : 2.mitotic figures : 2. 7 9
MR160013553,mass in left breast carcinoma breast,biopsy from left breast,received multiple grey white to grey brown linear cores measures 0.7 to 1cm. entire tissue is processed,section show linear cores of tissue harboring a neoplastic lesion in small clusters synctiatial sheets. the cells have round to oval pleomorphic hyperchromatic nuclei with abundant eosinophilic cytoplasm. extensive areas of desmoplasia noted.,left breastinvasive ductal carcinoma grade 2 mbr score (6 9)tubule formation 3nuclear pelomorphism 2mitotic figures 1 6 9
MR160013570,small perialeolar (n13x10cm) lesion in left breast carcinoma breast.,left breast biopsy.,received four grey white to grey brown linear cores ranging in length from 0.5 1 cm. entire tissue processed.,section shows linear cores of breast parenchyma with periductal inflammatory infiltrate comprising predominantly of lymphocytes histiocytes and macrophages. stroma shows hyaline change. no evidence of malignancy noted.,left breast biopsy :lymphocytic mastitis.no definite evidence of malignancy in the material submitted.kindly correlate clinically and suggest repeat if deemed necessary.
MR160013586,left breast lump carcinoma.,left breast lesion biopsy.,received four grey white to grey brown linear cores cores measuring 0.6 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in tubules and cords. the cells are ovoid having moderate amount of cytoplasm and hyperchromatic nucleus. mitotic figures are discerned. stroma shows desmoplasia with areas of hemorrhage.,left breast lesion biopsy :invasive ductal carcinoma grade 2.modified br score is 6 9.tubular formation : 2.nuclear pleomorphism : 2mitotic figures : 2 6 9
MR160013596,right breast lump carcinoma.,right breast biopsy.,received three grey white to grey brown linear cores measuring 0.7 to 1cm. entire tissue processed.,section shows linear cores of fibrofatty tissue with extensive areas of necrosis. occasional foci of atypical cellular clusters are seen. the cells are ovoid having moderate amount of cytoplasm moderately pleomorphic hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. areas of hemorrhage noted.,right breast biopsy :invasive ductal carcinoma grade 2.modified br score is 7 9.tubule formation : 3.nuclear pleomorphism : 2.mitotic figures : 2. 7 9 lymphovascular invasion seen.large areas of necrosis seen.
MR160013634,right breast lesion outside fnac.,right breast biopsy.,received four grey white to grey brown linear cores measuring 0.7 to 1cm. entire tissue processed.,section shows fragments of linear core demonstrating a neoplastic lesion arranged in sheets. the cells show marked pleomorohism with hyperchromatic nuclei and few showing prominent nucleoli with abundant eosinophilic cytoplasm. areas of demoplasia seen.,right breast biopsy :invasive carcinoma nuclear grade iii.suggestive of poorly differentiated origin.
MR160013686,mass in left breast carcinoma breast.,left breast mass biopsy.,received three grey white to grey brown linear cores measuring 0.8 to 0.9cm. entire tissue processed.,section shows breast parenchyma with an infiltrating neoplastic lesion arranged in cords and sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma shows desmoplasia with chronic inflammatory infiltrate.,left breast mass biopsy :invasive carcinoma grade 2.modified br score is 6 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160013694,complex cyst in left breast carcinoma breast.,left breast biopsy.,received four grey white to grey brown linear cores measuring 0.6 to 1cm. entire tissue processed.,section show multiple fragments of tissue harboring a lesion arranged in papillary pattern with fibrovascular core. the cells are columnar with basally located hyperchromatic nuclei and moderate to abundant cytoplasm. few of the cells are arranged in glandular pattern. foci of apocrine metoplasia seen.,left breast biopsy :suggestive of papillary neoplasm.suggest excision biopsy to rule out malignancy.
MR160013703,mass in right breast.carcinoma breast.,right breast biopsy.,received 3 grey white linear cores measuring 1.2 to 1.3cm. entire tissue processed.,section shows cores of breast tissue infiltrated by a lesion arranged in vague tubules nests and cords. cells are medium to large sized with round to oval hyperchromatic nucleus exhibiting moderate pleomorphism and moderate amount of eosinophilic cytoplasm. few cells show intranuclear inclusions. adjacent stroma shows fibrosis. focal areas of necrosis seen.,right breast biopsy :invasive ductal carcinoma grade 2.modified br score is 6 9.tubular formation : 3.nuclear pleomorphism : 2.mitotic figures : 1 6 9
MR160013714,mass in right breast carcinoma breast,biopsy from right breast,received multiple grey white to grey brown linear cores measures 0.7 to 1cmentire tissue is processed,section shows cores of breast tissue harboring a lesion arranged in nests and cords. cells are large with roundto oval pleomorphic hyperchromatic nuclei few showing prominent nucleoli and moderate to abundant fine granular eosinophilic cytoplasm. adjacent stroma shows extensive fibrosis. occasional mitotic figures discerned. areas of necrosis seen,right breast lesion biopsy:invasive ductal carcinoma grade 2mbr score 6 9 tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9 areas of necrosis seen.
MR160013757,mass in right breast carcinoma breast.,right breast mass biopsy.,received four grey white to grey brown linear cores measuring 0.7 to 1. 2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating neoplastic lesion arranged in cords and nests. the cells are ovoid having moderate of cytoplasm hyperchromatic nucleus and prominent nucleoli . mitotic figures are discerned. stroma shows desmoplasia with lymphoplasmacytic infiltrates. areas of hemorrhage seen.,right breast mass biopsy :invasive carcinoma grade 2.modified br score is 7 9.tubular formation : 3nuclear pleomorphism : 2.mitotic figures : 2 7 9
MR160013763,mass in left breast carcinoma breast.,biopsy from left breast mass.,received 3 grey white to grey brown linear cores measuring 0.6 to 0.7cm. entire tissue processed.,sections show linear cores of tissue with foci of dense collections of mixed inflammatory cells composed of polymorphic lymphocytes plasma cells and tiny clusters of atypical cells with hyperchroamtic nuclei are seen.,granulomatous inflammation with focus of atypical cells.suggest excision of lump for proper histopathological evaluation.
MR160013785,left breast lump carcinoma.,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 0.6 to 1cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords clusters and sheets. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromtic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,invasive ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR160013789,mass in right breast carcinoma breast.,biopsy from right breast.,received 3 grey to grey brown linear cores measuring 1 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords and compresed tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nuclioli and moderate cytoplasm. the intervening stroma is desmoplastic.,invasive ductal carcinoma biopsy from right breast.modified br score is 6 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160013895,mass in left breast carcinoma breast.,left breast mass biopsy.,received 3 grey white linear cores measuring 1.0 to 1.2cm. entire tissue processed.,section shows linear cores of breast tissue infiltrated by a neoplastic lesion arranged as tubules sheets and micropapillary pattern. the neoplastic cells have hyperchroamtic round to oval nuclei exhibiting marked pleomorphism. intervening stroma is desmoplastic.,left breast mass biopsy :suggestive of invasive carcinoma.modified br score is 4 9 grade 1.tubular formation : 2nuclear pleomorphism : 1mitotic figures : 1 4 9 kindly correlate with mammographic findings.
MR160013896,carcinoma left breast,biopsy from left breast,received multiple grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue is processed,section shows fibrocollagenous tissue with ductules lined by cuboidal to low columnar epithelium. stroma shows lymphocytes and occasional congested capillaries. no atypia is seen,left breast core biopsy:features are suggestive of chronic non specific mastitis.suggest repeat biopsy or excision of the lump if clinically indicated.
MR160013918,mass in left breast carcinoma breast.,left breast mass biopsy.,received 3 grey white linear cores measuring 1.2 to 1.4cm. entire tissue processed.,section from the linear cores shows breast parenchyma harboring neoplastic lesion with cells tubules nests and trabecular pattern. cells are pleomorphic with scanty cytoplasm and round to hyperchroamtic nuceli with inconspicuous nucleoli. stromal desmoplasia present with focal infiltration by lymphoplasmacytic infiltration. ductal carcinoma in site component (of intermediate nuclear grade ) is present.,left breast mass biopsy :invasive ductal carcinoma grade 2.modified br score is 6 9.tubular formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR160013972,mass in left breast carcinoma breast.,left breast mass biopsy.,received 3 grey white to grey brown linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows linear cores of breast tissue infiltrated by a neoplastic lesion arranged as solid sheets cords and trabecular pattern. the neoplastic cells have hyperchromatic nuclei marked pleomorphism noted. adjacent stroma shows necrosis fibrosis and hemorrhage. congested blood vessels seen. brisk mitosis noted.,left breast mass biopsy :invasive carcinoma grade iii.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR160013976,large right breast lump carcinoma right breast.,left breast biopsy.,received three grey white linear cores measuring 1 to 1.1cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma demonstrating a neoplastic lesion arranged in trabeculae sheets cords exhibiting marked pleomorphism with round to oval hyperchromatic nuclei with abundant cytoplasm. adjacent stroma shows necrosis fibrosis desmoplasia. congested blood vessels noted. mitotic figures discerned.,left breast biopsy :invasive carcinoma grade ii.modified br score is 6 9tubular formation : 2nuclear pleomorphism : 3mitotic figures : 1 6 9
MR160013988,right breast lump carcinoma breast.,right breast lump biopsy.,received three grey white linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows linear cores of breast tissue infiltrated by a neoplasm arranged as sheets cords and in trabecular pattern. the neoplastic cells have hyperchromatic nuclei and moderate amount of cytoplasm. the intervening stroma is desmoplastic.,right breast lump biopsy.invasive ductal carcinoma grade ii.modified br score is 6 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR160014013,left breast lump carcinoma.,biopsy from left breast.,received 5 grey white to grey brown linear cores measuring 2 to 1.4cm. entire tissue processed.,linear cores of breast tissue harboring neoplasm arranged in papillary pattern. foci suggestive of ductal carcinoma in situ noted. the intervening stroma is desmoplastic.,papillary neoplasm with foci suggestive of ductal carcinoma in situ biopsy from left breast.in view of desmoplastic stroma presence of invasive component needs to be excluded on excision biopsy.case discussed with dr.senthil rajappa
MR160014063,carcinoma breast left,biopsy from left breast,received multiple grey white to grey brown linear cores measures 0.8 to 1.2cm. entire tissue is processed,linear cores of breast parenchyma show extensive desmoplasia of the stroma. there are numerous cells arranged as cords exhibiting crush artifacts. focally they are pleomorphic. no significant mitotic activity is noted.however numerous crush artifacts with few atypical cells seen,left breast biopsy:the features are suspicious of malignancyneeds ihc
MR160014066,carcinoma right breast,(a) right breast wide excision of the lump (b) sentinel lymph nodes from right axilla.,a) received lumpectomy specimen measures 5 x 4.2 x 0.5 cm.skin ellipse measuring 3 x 1 cm. cut surface shows grey white lesion measuring 2 x 1 x 1.3 cm. located at the following distances from the respective margins:superior margin 0.5cminferior margin 3cmmedial margin 1cmlateral margin 1.5cmdeep margin 1cmone nodular lesion measures 1 x 0.5 x 0.3 cm located 1cm away from tumor (grey white lesion) cut surface is whorled.representative sections are submitted. b) received fibrofatty tissue measures 2.5 x 2 x 0.5 cm one lymph node identified measures 1.5 x 0.5 x 0.3 cm cut surface shows fatty infiltration.,section shows tumor cells in nests cords and diffuse sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular or perineural invasion is not identified.,a) right breast wide excision :invasive ductal carcinoma grade 2. modified bloom richardson score is 6 (3+2+1). tumor measures 2.0 cm in greatest dimension. lymphovascular invasion is not identified. perineural invasion is not identified. ductal carcinoma in situ of solid and cribriform pattern with intermediate nuclear grade. adjacent breast shows features of fibroadenomatoid change. all margins of resection are free of tumor. overlying skin is free of tumor. b) sentinel lymph nodes right axilla :six lymph nodes are identified negative for malignancy (0 6)pathological stage : pt1cn0
MR160014099,mass in right breast carcinoma breast,biopsy from right breast,received multiple grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue is processed,sections studied shows linear cores of tissue harboring extensive necrosis and a small volume of lesion arranged in sheets. the neoplastic cells have moderate amount of cytoplasm pleomorphic round to oval hyperchromatic nuclei.,right breast mass biopsy:small volume of invasive carcinomakindly note tumor volume may not be adequate for further work up repeat biopsy is advisable
MR160014111,known case of ductal carcinoma of left breastmultiple left axillary nodes with thickened cortex metastatic nodes,biopsy from left axillary node,received multiple grey white to grey brown linear cores measures 1 to 1.5cm. entire tissue is processed,section shows cores of tissue infiltrated by tumor cells in nests and sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left axillary nodes biopsy:positive for malignancy.suggestive of metastatic tumor deposits in known case of ductal carcinoma left breast.
MR160014116,mass in left breast fibroadenoma,biopsy from left breast,received 3 grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue is processed,section shows cores of fibrous tissue harboring an infiltrate lesion arranged in diffuse sheets cords and in papillary pattern with fibrovascular cores. cells exhibit marked nuclear pleomorphism hyperchromatic to vesicular irregular nuclei dispersed chromatin moderate eosinophilic to clear cytoplasm. mitotic figures brisk. abundant areas of necrosis and karyorrhectic debris seen,left breast core biopsy :invasive carcinoma grade 3. modified bloom richardson score is 9(3+3+3).suggest further confirmation of morphology on resection specimen.
MR160014121,mass in left breast carcinoma breast,biopsy from left breast,received multiple grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue is processed,sections studied from linear cores of breast parenchyma shows a neoplastic lesion arranged in tubules cords and solid pattern. the neoplastic cells have moderate amount of cytoplasm pleomorphic round to oval hyperchromatic nuclei. lymphovascular invasion is seen,invasive ductal carcinoma biopsy from left breast:grade 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9 lymphovascular emboli seen
MR160014145,mass in right breast carcinoma breast,biopsy from right breast,received multiple grey white to grey brown linear cores measures 0.8 to 1.0cm.entire tissue is processed,sections from the linear cores shows breast parenchyma harboring a neoplastic lesion with cells arranged in sheets and trabecule. cells are highly pleomorphic with scanty to moderate cytoplasm and round to oval hyperchromatic nuclei. areas of necrosis and hemorrhage present,right breast mass biopsy:invasive ductal carcinoma grade 2mbr score 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2
MR160014168,know case of carcinoma left breast post mrm.now right breast lesion.,biopsy from right breast lesion.,received 4 grey white linear cores measures 0.6 to 1cm. entire tissue processed.,section show linear cores of breast parenchyma harboring tumor composed of round to oval cells with hyperchromatic enlarged nucleus and scant cytoplasm infiltrating as cords and small nests. nuclear pleomorphism is moderate. mitosis are discerned. stroma shows desmoplasia.,biopsy from right breast lesion(know case of carcinoma left breast status post op) :invasive carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR160014183,left breast lump carcinoma.,biopsy from left breast.,received 4 greywhite to greybrown linear cores measuring 0.8 to 1cm. entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged as islands and sheets. the neoplastic cells exhibit moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,biopsy from left breast:invasive carcinoma biopsy from left breast.mbr score is 6 9 grade 2 tubule formation 3 nuclear pleomorphism 2 mitoses 1.
MR160014195,left breast lump carcinoma,biopsy from left breast,received multiple grey white to grey liner cores measures 0.5 to 1cm. entire tissue is processed,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1700024,left breast lump carcinoma,biopsy from left breast,received multiple grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue is processed,section shows cores of tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson scores 6(3+2+1)
MR1700094,right breast lump carcinoma,biopsy from right breast lump,received multiple grey white to grey brown linear cores measures 0.5 to 1.2cm. entire tissue is processed,section shows linear cores of breast parenchyma infiltrated by a lesion arranged as cords tubules and sheets. the cells have round to oval hyperchromatic pleomorphic nuclei inconspicuous nucleoli and scanty to moderate cytoplasm. ductal carcinoma in situ with comedonecrosis seen. stroma shows inflammatory infiltrate.,biopsy from right breast lump:invasive ductal carcinoma grade 2mbr score is 7 9tubule formation 3nuclear pleomorphism 2mitotic figures(6 7 10hpf) 2ductal carcinoma in situ with comedonecrosis seen.
MR1700095,right breast lump carcinoma.,biopsy from right breast lump.,received 5 greywhite to greybrown linear cores measuring 1 to 1.2cm. entire tissue processed.,linear cores of breast tissue harboring scant volume of atypical cells arranged in cords. these cells have hyperchromatic nuclei and scant to moderate cytoplasm.,scant volume of atypical cells seen.a repeat biopsy is available for confirmation and ancillary tests.case discussed with dr sai rajendra.
MR1700122,left breast mass,biopsy of left breast,received multiple grey white to grey brown linear cores measures 1 to 1.2 cm. entire tissue is processed,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1700134,left breast lump carcinoma.,biopsy from left breast lump.,received 4 grey white to grey brown linear soft tissue bits measuring 0.8 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a cellular infiltrating lesion arranged in sheets. the cells are ovoid having moderate amount of cytoplasm and hyperchromatic nucleus. the stroma is desmoplastic with numerous lymphocytic infiltrates. mitotic figures are discerned.,biopsy from left breast lump:invasive carcinoma nst.mbr score is 7 of 9 (grade 2).tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1700157,right breast retroareolar mass carcinoma right breast,biopsy of right breast,received multiple grey white linear cores measures 1 to 1.2cm. entire tissue is processed,section shows linear cores of breast parenchyma harboring a lesion arranged as nests cords and tubules. the cells have pleomorphic nuclei and moderate cytoplasm. stroma shows desmoplasia,biopsy from right breast lumpinvasive ductal carcinoma grade 1tubule formation 2nuclear pleomorphism 2mitotic figures(4 5 10hpf) 1 mbr score 5 9
MR1700190,right breast mass,biopsy from right breast,received multiple grey white linear cores measures 0.6to 0.8cm. entire tissue is processed,linear cores of breast tissue harboring a neoplasm arranged as tubules cords and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic. lymphovascular emboli seen,invasive ductal carcinoma biopsy from right breastgrade 2 tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR1700231,right breast mass,biopsy from right breast mass,received multiple grey white linear cores measures 1 to 1.3cm. entire tissue is processed,section shows linear cores of breast parenchyma infiltrated by a lesion arranged as tubules cords and sheets. the cells have round to oval hyperchromatic moderately pleomorphic nuclei with moderate to scanty cytoplasm. stroma shows desmoplastic reaction. areas of necrosis noted. ductal carcinoma in situ with comedonecrosis present,biopsy from right breast massinvasive ductal carcinoma grade 2mbr score 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9 ductal carcinoma in situ with comedonecrosis present
MR1700259,left breast lump carcinoma.,left breast core biopsy.,received 5 grey white linear core measuring 0.8 to 1.2cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1700264,small left breast lump carcinoma,biopsy from left breast lump,received multiple grey white to grey brown linear cores measures 1 .1 to 1.4cm.,section shows invasive sheets of nests and dysplastic cells showing moderate anisonucleosis hyperchromatic nuclei of prominent nucleoli seen invading the dense desmoplastic stroma few mononuclear infiltrates seen,invasive ductal carcinoma grade ii left breasttubule formation 3nuclear pleomorphism 2mitotic figures 2 mbr score 7 9
MR1700283,left breast lump carcinoma breast,biopsy of left breast,received multiple grey white linear cores measures 1.2 to 1.5cm. entire tissue is processed,section shows linear cores of fibrocollagenous tissue harboring a lesion arranged as diffuse sheets. the cells are round to oval with hyperchromatic markedly pleomorphic nuclei and scanty to moderate cytoplasm. few interspersed large cells with vesicular nucleus and prominent nucleoli noted. intervening stroma shows inflammatory infiltrate. areas of necrosis noted,biopsy from left breast lumpinvasive carcinoma. nos probably of ductal originnuclear grade ii areas of necrosis seen
MR1700294,right breast lump carcinoma.,right breast core biopsy.,received 3 grey white to grey brown linear core measuring 1 to 1.2cm. entire tissue processed.,section shows interlacing fascicles of spindle cells. individual cells have mild to moderate atypia. no ductules are seen.mitosis is discerned.,right breast core biopsy :spindle cell lesion. phyllodes tumour.suggest excision of the lump for further confirmation.
MR1700317,carcinoma ovary right breast mass.,a) biopsy from colon.b) biopsy from right breast lesion.,a) received multiple greywhite soft tissue bits altogether measuring 0.8x0.5x0.5cm. entire tissue processed.b) received 3 greywhite to greybrown linear core measuring 0.8 to 1.0cm. entire tissue processed.,a) multiple fragments of colonic mucosa exhibiting features of denudation ulceration and focal hyperplasia with distorted glands. few glands are dilated and filled with mucin. mitotic figures are discerned. there are foci of extravasated mucin ann mixed inflammatory infiltrate. intervening fibrocollagen stroma demonstrate numerous vascular channels.b) linear cores of tissue exhibiting a neoplastic lesion arranged in nests and tubular configuration consisting of round to cuboidal cells demonstrating moderate nuclear pleomorphism and eosinophilic cytoplasm amidst a desmoplastic stroma. mitotic figures are discerned.,a) biopsy from colon:superficial biopsy rectal ulcer with reactive atypiab) biopsy from right breast lesion:invasive carcinoma nst grade ii.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1700322,right breast mass.,right breast mass core biopsy.,received 4 grey white linear cores measuring 0.8 to 1.0cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuceli and moderate amount of cytoplasm.,right breast mass core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1700327,left breast mass,biopsy from left breast mass,received multiple grey white to grey brown linear cores measures 1 to 1.5cm.entire tissue is processed,section shows linear cores of breast parenchyma harboring a lesion arranged as tubules and cords. the cells have round tooval hyperchromatic nuclei with moderate pleomorphism and moderate cytoplasm. stroma shows focal inflammatory infiltrate,biopsy from left breastinvasive ductal carcinoma grade 2mbr score is 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR1700340,metastasis of unknown origin. primary in breast.,right axillary node.,received single lymph node measures 2.5x1.5x1 cm. cut surface : grey white to grey yellow.,section shows lymph node with an infiltrating lesion in parenchyma arranged in sheets cords and tubules. the cells are ovoid having moderate amount of pale eosinophilic cytoplasm vesicular to hyperchromatic and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia. areas of hemorrhage and necrosis seen. extranodal extension is seen.,right axillary lymph node biopsy:suggestive of metastatic adenocarcinoma in one of the two isolated lymph nodes are involved by tumor(1 2).extranodal extension is seen.suggest ihc.please correlate clinically.
MR1700359,right breast lungs carcinoma breast.,biopsy from right breast.,received 3 grey white to grey brown linear core meassured 1 to1.2cm. entire tissue processed.,section sows linear cores of breast parenchyma infiltrated by a lesion arranged as tubules cores and nests. the cells have round to oval hyperchromatic pleomorphic nuclei coarse chromatin and scanty to moderate cytoplasm. areas of necrosis noted.,biopsy from right breast:infiltrating ductal carcinoma grade ii.modified br score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures (6 8 10hpf : 2 6 9
MR1700375,mass in left breast carcinoma breast,biopsy of left breast,received multiple grey white linear cores measures 0.8 to 1cm.entire tissue is processed,section shows linear cores of breast parenchyma harboring a lesion arranged as nests tubules and cords. the cells have round to oval hyperchromatic markedly pleomorphic nuclei scanty to moderate cytoplasm.ductal carcinoma in situ(solid type) present. stroma shows focal lymphocytic infiltrate,biopsy from left breast:invasive ductal carcinoma grade 2tubule formation 2nuclear pleomorphism 3mitotic figures (6 7 10hpf) 2 7 9 ductal carcinoma in situ (solid type) present
MR1700402,left breast mass,biopsy of left breast mass,received multiple grey white cores soft tissue bits measures 0.8 1.1cm. entire tissue is processed,section shows linear cores of breast parenchyma harboring an infiltrating cellular lesion arranged in tubules cords and sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with inflammatory infiltrates. areas of hemorrhage and necrosis seen,left breast mass biiopsy:invasive carcinoma nst grade 2tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9 areas of necrosis seen
MR1700435,carcinoma left breast,a) wide local excision b)left axillary nodesc) level ii lymph nodes,a) wide local excision :received skin covered fibrofatty tissue measuring 6x6x5cmcut surface shows grey white area measures 1.5x1x1cm skin ellipse measures 7.5x2cm.distance of the lesion from the following margins are:superior margin 1.5cminferior margin 1.5cmmedial margin 2.0cnlateral margin 2.2cmdeep margin 1cmb) axillary nodes:received fibrofatty tissue measures 7x5.5x2cm largest lymph node measures 2x2x1cm cut surface shows grey brown fatty infiltrationc) level ii lymph nodes:received fibrofatty tissue measures 4x2x1cm isolated 5 nodes entire tissue processed.,a) wide local excision :tumor bed: residual tumor present measures 1.5x1x1cm with invasive ductal carcinoma focal areas of fibrosis necrosis and lymphocytic infiltration is presentmbr score 6 9 tubule formation 3 nuclear pleomorphism 1 mitotic figures 2 6 9 nuclear grade iiductal carcinoma in situ not presentlymphovascular invasion not presentresected margin : superior margin free of tumorinferior margin free of tumorlateral margin free of tumormedial margin free of tumor deep margin free of tumorb) axillary nodes:12 nodes no deposits of tumorc) level ii lymph nodes:5nodes no deposits of tumor,a. wide local excision left breast post nactresidual viable tumor presentinvasive ductal carcinoma grade iimbr score 6 9 tubule formation 3 nuclear pleomorphism 1 mitotic figures 2 6 9 maximum dimension of tumor is 1.5cmnuclear grade iiductal carcinoma in situ not presentlymphovascular invasion not presentall resected margins free of tumoraxillary lymph nodes 12 nodes no deposits of tumorlevel ii nodes 5 nodes no deposits of tumor
MR1700502,right breast mass,biopsy from right breast,received multiple grey white to grey brown linear cores measures 1 to 1.5cm. entire tissue is processed,section shows linear cores of breast parenchyma infiltration by a lesion arranged as nests and tubules. the cells have hyperchromatic pleomorphic nuclei and scanty to moderate cytoplasm. stroma shows inflammatory infiltrate.,biopsy from right breastinvasive ductal carcinoma grade iimbr score is 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR1700565,left breast mass,biopsy from left breast mass,received multiple grey white to grey brown linear cores measures 1 to 1.5cm.entire tissue is processed,section shows cores of breast parenchyma infiltrated by a lesion arranged in nests cords and trabeculae. cells are large with pleomorphic round to oval hyperchromatic nuclei with irregular contour inconspicuous nucleoli and moderate to abundant eosinophilic to clear cytoplasm.focal areas show linear arrangement of cells exhibiting indian file pattern. extensive stromal desmoplasia noted. areas of necrosis seen,left breast mass biopsy:suggestive of ductal carcinomanuclear grade 2
MR1700578,left breast mass.,biopsy from left breast mass biopsy.,received 5 greywhite to greybrown linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows cores of breast parenchyma infiltrated by a lesion arranged in nests cords and sheets of atypical cells with round to oval vesicular to hyperchromatic pleomorphic nuclei inconspicious nucleoli irregular nuclear borders and moderate amount of pale eosinophilic cytoplasm. interspersed are lymphocytes and plasma cells. stroma shows fibrosis and areas of hemorrhage.,left breast mass biopsy:invasive carcinoma grade 2.mbr score : (3+2+2) : 7 9.
MR1700584,mass in left breast carcinoma breast,biopsy from left breast mass,received multiple grey white to grey brown linear cores measures 1 to 1.5cm. entire tissue is processed,sections show linear cores of breast tissue harboring a lesion arranged in tubules cords and trabeculae. cells have scanty cytoplasm hyperchromatic nuclei and inconspicuous nucleoli. stroma shows desmoplasia,left breast mass biopsy:invasive ductal carcinoma grade 2mbr score 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1700613,mass in right breast carcinoma breast,biopsy from right breast,received multiple grey white to grey brown linear cores measures 0.7 to 1cm.entire tissue is processed,section shows cores of breast tissue with tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm,right breast mass core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1700631,left breast mass.,biopsy from left breast.,received 6 grey white to grey brown linear cores measuring 5 to 1cm. entire tissue processed.,section show linear cores from breast parenchyma harboring a neoplastic lesion arranged in nests trabeculae and focal tubular pattern. neoplastic cells have moderate cytoplasm with hyperchromatic nuclei and prominent nucleoli. areas of necrosis present.,invasive ductal carcinoma biopsy from left breast.modified br score is 7 9 grade ii.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 areas of necrosis seen.
MR1700687,left neck node metastatic,biopsy from left neck node,received multiple grey white linear cores measurs 0.5 to 1cm. entire tissue is processed,section shows linear cores of fibrofatty and fibromuscular tissue infiltrated by a lesion arranged in nests and cords comprising of atypical cells with pleomorphic round to oval to angulated hyperchromatic nuclei few showing vesicular chromatin with prominent nucleoli with moderate to abundant pale granular to eosinophilic cytoplasm.atypical mitotic figures discerned. adjacent stroma shows extensive fibrosis. areas of necrosis noted with lymphoplasmacytic infiltrate. nodal tissue not identified,left neck node biopsy:suggestive of metastatic carcinomaplease look for primary in breast and lungsuggest ihc
MR1700730,mass in left breast carcinoma breast,biopsy from left breast mass,received multiple grey white to grey brown linear measures 1 to 1.5 cm entire tissue processed,section shows linear cores of breast parenchyma harboring a lesion arranged as cords nests and tubules. the cells have round to oval hyperchromatic nuclear with moderate nuclear pleomorphism and scanty to moderate cytoplasm. stroma shows inflammatory infiltrate and desmoplasia.,biopsy from left breast massinvasive ductal carcinoma. grade 2.modified br score is 6 9tubule formation 2nuclear pleomorphism 2mitosis figures 2 6 9 areas of necrosis seen.
MR1700771,mass in left breast carcinoma breast.,biopsy from left breast lesion.,received 3 grey white to grey brown linear cores measuring 0.8 to 1cm. entire tissue processed.,linear cores of tissue exhibiting dyscohesive sheets and nests of round to oval cells with eccentrically placed nuclei demonstrating moderate nuclear pleomorphism and eosinophilic cytoplasm. binucleated cells are also noted. mitotic figures are discerned. intervening areas show fibrocollagenous stroma and pale mucinous material.,biopsy from left breast lesion :carcinoma breast with features suggestive of mucinous carcinoma grade 2.modified br score is 6 9.tubular formation : 3nuclear pleomorphism : 2.mitotic figures : 1 6 9
MR1700773,left breast mass.,biopsy from left breast mass.,received 4 grey white to grey brown linear cores measures 0.7 to 1cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,biopsy from left breast mass :invasive ductal carcinoma grade 2. modified bloom richardson score is 6 (3+2+1).
MR1700778,mass in left breast carcinoma breast.,left breast mass core biopsy.,received 3 grey white to grey brown linear cores 1 to 1.3 cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson sore is 6(3+2+1).
MR1700807,left breast mass carcinoma breast,biopsy from left breast mass,received 5 grey white to grey brown linear cores measuring 0.5 to 1 cm. entire tissue processed,section shows linear cores of tissue harboring a lesion arranged as tubules and cords comprising of cells with round to oval hyperchromatic pleomorphic nuclei and infiltrate and sclerosis.,biopsy from left breast massinvasive ductal carcinoma grade 2modified br score is 6 9tubule formation 2nuclear pleomorphism 2 mitosis figures 2 6 9
MR1700816,known case of carcinoma left breast.,excision of the sinus tract left breast post bcs and rt.,received skin covered fibrofatty tissue measures 4.5x3x2cm skin measures 2.5x1cm. surface show linear scar withsinnus tract measures 1cm. custsurface show a grey white to grey brown area measures 1.5x1x0.8cm. distance from margins :superior margin : 0.5cm.inferior margin : 1cm.medial margin : 0.5cm.lateral margin : 1.5 cm.deep margin : 1 cm.,section studied shows breast parenchyma with overlying skin showing focal ulceration. sinus tract is identified lined by inflammatory granulation tissue comprising of lymphomononuclear cell infiltrate and foreign body giant cells. also seen is surrounding stromal edema and hyalinisation. no evidence of atypia or malignancy is noted in material submitted.,excision of the sinus tract left breast post bcs and rt. sinus tract with chronic non specific inflammation.no evidence of malignancy noted in the material submitted.
MR1700851,mass in right breast carcinoma breast.,biopsy from right breast mass.,received 4 grey white to grey brown linear cores measuring 0.6 to 1cm. entire tissue processed.,section shows linear cores of tissue with a neoplastic lesion arranged in vague islands and sheets.individual cells pleomorphic round to oval hyperchromatic nuclei inconspicuous nucleoli and moderate amount of cytoplasm. stroma shows plump spindle cells. areas of necrosis hemorrhage and karyorrhectic debris noted.,right breast core biopsy :invasive carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1700857,mass left breast carcinoma .,biopsy from left breast mass.,received 4 grey white to grey brown linear core 0.5 to 1.0 cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue infiltrated by a lesion arranged as tubules and nests. the cells have round to oval hyperchromatic pleomorphic nuclei with moderate to abundant eosinophilic to clear cytoplasm. stroma shows inflammatory infiltrate and fibrosis.,biopsy from left breast mass.invasive ductal carcinoma grade 2.modified br score in 7 9.tubule formation 2.nuclear pleomorphism 2.mitosis (11 12 10 hpf) 3. 7 9
MR1700859,right breast mass.,biopsy from right breast.,received 3 grey white to grey brown linear cores measuring 1.2 to 1.4cm. entire tissue processed.,section show linear cores with breast parenchyma harboring a neoplastic lesion arranged in nest and trabecular pattern. neoplastic cells are hyperchromatic with scanty cytoplasm and round to oval nuclei. occasional bizarre form noted. stroma shows desmoplasia.,invasive ductal carcinoma biopsy from right breast mass.modified br score is 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2.mitotic figures : 1 6 9
MR1700894,left breast mass at 3 0 clock position.,left breast core biopsy.,received 4 grey white to grey brown linear cores measuring 1.2 to 1.4 cm. entire tissue processed.,section shows tumor cells in nests cords and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. ductal carcinoma in situ of cribriform pattern is seen.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). ductal carcinoma in situ of cribriform pattern with intermediate nuclear grade is seen.
MR1700916,right breast mass.,right breast mass core biopsy.,received 3 grey white to grey brown linear cores measuring 1.0 to 1.4cm. entire tissue processed.,section shows cores of tissue infiltrated by ductal carcinoma in situ. no definite evidence of invasive malignancy is seen.,right breast mass core biopsy :shows ductal carcinoma in situ of solid cribriform and comedo pattern with intermediate nuclear grade.no definite evidence of invasive malignancy is seen.suggest excision of the the lump for further confirmation of invasive component.
MR1700932,mass in right breast carcinoma breast.,biopsy from right breast mass.,received 4 grey white to grey brown linear cores measuring 0.8 to 1 cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged as tubules and cords. the cells have round to oval hyperchromatic pleomorphic nuclei with moderate cytoplasm. stroma shows desmoplasia.,biopsy from right breast mass.invasive ductal carcinoma grade 2.modified br score is 6 9.tubule formation 2.nuclear pleomorphism 2.mitosis (6 7 10 hpf) 2. 6 9
MR1700961,mass in right breast carcinoma breast.,biopsy from right breast mass.,received 3 grey white linear core measuring 0.8 to 1.0 cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a lesion arranged as tubules cords and sheets. the cells have round to oval hyperchromatic nuclear with moderate atypia and moderate cytoplasm. ductal carcinoma in situ (solid type present). stroma shows inflammatory infiltrate.,biopsy from right breast mass.invasive ductal carcinoma grade 2.modified br score is 6 9.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 ductal carcinoma in situ present.
MR1701012,mass in left breast carcinoma breast.,left breast mass core biopsy.,received 3 grey white to grey brown linear cores measuring 0.8 to 1.0cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1701022,mass in left breast carcinoma breast.,biopsy from left breast mass.,received 3 grey white to grey brown linear cores measuring 0.7 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a linear arranged as tubules cords and sheets. the cells have round to oval hyperchromatic nucleus with moderate atypia and scanty to moderate cytoplasm. stroma shows myxoid change.,biopsy from left breast mass :invasive ductal carcinoma grade 2.modified br score is 7 9.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 3 7 9
MR1701031,right breast lump carcinoma.,right breast lump core biopsy.,received 4 grey white to grey brown linear cores measuring 0.5 to 1cm. entire tissue processed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuceli and moderate amount of cytoplasm. large areas of sclerosis are seen.,right breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1701046,right breast mass.,biopsy from right breast mass.,received 4 grey white to grey brown linear cores measuring 0.4 to 0.8.entire tissue processed.,linear cores of breast tissue harboring neoplastic cells arranged in cords and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is fibrous.,invasive carcinoma with lobular features biopsy from right breast modified bloom richardson score 6 9 grade 2tubule formation :3nuclear pleomorphism :2mitotic figures :1 6 9
MR1701062,left breast lump carcinoma left breast.,biopsy from left breast.,received 5 grey white to grey brown linear cores measuring 1 to 1.5cm. entire tissue processed.,section shows breast parenchyma with infiltrating sheets and nests of dysplastic ductal cells showing moderate pleomorphism hyperchromatic nuclei and prominent nucleoli. foci of ductal carcinoma in situ with comedonecrosis seen. the intervening stroma is desmoplastic.,invasive ductal carcinoma.modified br score is 6 9 grade ii.tubular formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 ductal carcinoma in situ with comedonecrosis seen.
MR1701066,mass in right breast carcinoma breast.,right breast mass biopsy.,received 3 grey white to grey brown linear core measuring 0.9 to 1.2cm. entire tissue processed.,section from the linear cores shows breast parenchyma harboring a neoplastic lesion arranged in nests trabeculae and tubules cells are polymorphic with scanty cytoplasm round to oval hyperchromatic nuclei with prominent nucleoli. stroma shows desmoplasia.,right breast mass biopsy:invasive ductal carcinoma grade 2.modified bloom richardson score 6( 2+2+2).
MR1701107,right breast lung carcinoma right breast .,trucut biopsy of right breast lung for hpe.,received 3 grey white to grey brown linear cores measuring 1 to 0.2.entire tissue is processed.,section shows breast parenchyma showing invasive nets and sheets of dysplastic ductal cells showing moderate anisonucleosis hyperchromatic nuclei and prominent nucleoli. focus of ductal carcinoma in situ with comedonecrosis seen. the intervening stroma is desmoplastic and mononuclear intilrates.,invaise ductal carcinoma right breastmodified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 focus of ductal carcinoma in situ seen.
MR1701108,right breast mass.,biopsy from right breast lesion.,received 4 greywhite to greybrown linear core measuring 0.5 to 1cm. entire tissue processed.,linear cores of breast parenchyma exhibiting a neoplastic lesion arranged as nests tubules islands demonstrating moderate nuclear pleomorphism and eosinophilic cytoplasm amidst a desmoplastic stroma. mitotic figures are discerned. moderate to dense lymphocytic infiltrates interspersed in a desmoplastic stroma.,biopsy from right breast lesion:invasive ductal carcinoma grade iii.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR1701118,few hyperechoic right breast nodule carcinoma right breast.,biopsy from right breast.,received 5 grey white to grey brown linear cores measuring 0.8 to 1.0cm. entire tissue processed.,sections shows sheets of dysplastic ductal cells arranged in dyscohesive nest and sheets showing mild anisonuclosis and hyperchromatic nuclei. pools of extracellular mucin seen.,invasive carcinoma.suggestive of mucinous carcinoma right breast.
MR1701129,mass in left breast carcinoma breast.,left breast mass core biopsy.,received 3 grey white to grey brown linear cores measuring 0.4 to 0.6 cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchroamtic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1701135,right breast mass.,biopsy from right breast lesion.,received 4 grey white to grey brown linear cores measuring 0.6 to 0.8cm. entire tissue processed.,linear cores of breast parenchyma exhibiting a neoplastic lesion arranged in sheets tubules nests consisting of round to oval cells demonstrating moderate nuclear pleomorphism and eosinophilic cytoplasm amidst fibrocollagenous stroma. there are aggregates of lymphoplasmacytic infiltrate. area of necrosis seen.,biopsy from right breast lesion :invasive ductal carcinoma grade ii.tubular formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1701157,right breast mass.,right breast mass core biopsy.,received 4 grey white to grey brown linear cores measuring 0.7 to 1cm. entire tissue processed.,section shows cores of tissue infiltrated by ductal carcinoma in situ. no definite evidence of invasive malignancy is seen.,right breast mass core biopsy :shows ductal carcinoma in situ of cribriform and solid pattern with intermediate nuclear grade.suggest repeat biopsy or excision of the lump for further confirmation of invasive component.
MR1701202,birads iv lesion in right breast.,biopsy form right breast mass.,received 4 grey white to grey brown linear cores 0.3 to 0.6cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue with small focus showing cords and tubules of atypical cells with hyperchromatic pleomorphic nucleus and moderate cytoplasm. stroma shows focal inflammatory infiltrate.,biopsy from right breast:small focus of invasive carcinoma.please note :tumor volume is scant to attempt further workup.
MR1701218,left breast mass.,biopsy left breast.,received 3 grey white to grey brown linear cores measuring 0.5 to 0.8cm. entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as tubules and clusters.the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm.foci of cribriform ductal carcinoma in situ seen. the intervening stroma is flbrous.,invasive ductal carcinoma biopsy from left breast grade2(7 9)tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9 foci of cribriform ductal carcinoma in situ noted.
MR1701231,left breast mass.,left breast cores biopsy.,received 3 grey white to grey brown linear measuring 0.5 to 1cm. entire tissue processed.,section show linear cores of breast parenchyma with neoplastic lesion arranged in cords and sheets. individual cells have pleomorphic round to oval hyperchromatic nuclei and moderate amount of cytoplasm .stroma show desmoplasia with inflammatory cells consisting of lymphocytes. ductal carcinoma in situ solid pattern identified.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). ductal carcinoma in situ of solid pattern with intermediate nuclear grade is seen.
MR1701335,right nipple discharge,right ductal system cone excision biopsy,fresh tissue received : formalin. laterality : rightspecimen orientation : orientatedsuperior margin : 0.4cminferior margin : 0.5cmmedial margin : 0.8cmlateral margin : 0.4cmdeep margin : 0.2cmspecimen size : 4.4x3.6x1.5cm while serial sectioning dilated ducts seen along with grey white areas measures 1.2x1x1cm.,sections reveal breast parenchyma demonstrating dilated ducts exhibiting diffuse proliferation of monotonous population of round to oval cells with centrally placed nuclei and moderate amount of pale eosinophiliccytoplasm. there are intervening vascular channels.,right ductal system cone excision biopsy:suggestive of ductal carcinoma in situsuggest ihclesion measures 1cm in the greatest dimension no lymphovascular or perineural invasion seenmargins: superior margin free of tumorinferior margin free of tumormedial margin free of tumorlateral margin free of tumordeep margin is close measures 0.2cm however inked margin is free from tumor
MR1701345,right breast mass.,biopsy from right breast mass.,received 4 grey white to grey brown linear cores 0.8 to 1cm.entire tissue processed.,section shows linear cores of breast parenchyma with extensive areas of ductal carcinoma in situ.comedonecrosis identified. stroma shows inflammatory infiltrate and myxoid change.,biopsy from right breast mass:invasive ductal carcinoma with ductal carcinoma in situ and comedonecrosis (nuclear grade 2) .
MR1701348,right breast mass.,right breast mass biopsy.,received 4 grey white to grey brown linear cores measuring 0.5 to 1cm. enter tissue processed.,section shows linear cores of breast parenchyma harboring an filtrating cellular lesion arranged in tube nests and sheets.the cells are atypical ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma shows desmoplasia with inflammatory infiltrate.,right breast mass biopsy invasive ductal carcinoma grade : 2tubule formation 2mitotic figures 2nuclear pleomorphism 2 6 9
MR1701372,mass in right breast carcinoma breast.,right breast core biopsy.,received 5 grey white to grey brown linear cores measured 0.5 to 1 cm . entire tissue processed.,section shows tumor cells in diffuse sheets nest and papillary pattern. individual cells have hyperchromatic nuclei moderate amount of cytoplasm.,right breast cores biopsy:invasive ductal carcinoma grade 2. modified bloom richardson scare 6(3+2+1).
MR1701386,left breast mass.,left breast mass core biopsy.,received 3 grey white to grey brown liner cores measuring 0.8 to 1cm. entire tissue processed.,section from the linear cores of tissue shows a neoplastic lesion arranged in nests cords and tubules cells are pleomorphic with scanty cytoplasm round to oval hyper chromatic nuclei with inconspicuous nucleoli stroma shows desmoplasia.,left breast mass core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1701388,mass in left breast carcinoma breast.,left breast mass biopsy.,received 3 grey white to grey brown linear cores measuring 0.8 to 1cm. entire tissue processed.,section shows breast parenchyma harboring infiltrating lesion comprising of round to oval cells arranged in diffuse sheets and nests. cells having highly pleomorphic hyperchromatic nuclei few cells showing prominent nucleoli with moderate to scant cytoplasm. adjacent stroma shows desmoplasia. areas of necrosis hemorrahge noted. mitotic figures 8 10 hpe.,left breast mass biopsy: invasive ductal carcinoma grade 3tubule formation score 3nuclear pleomorphism 3mitotic figures 2
MR1701402,mass in right breast carcinoma breast,biopsy from right breast mass.,received 4 grey white to grey brown linear cores measured 0.5 to 1cm . entire tissue processed.,section shows linear core of tissue harboring a lesion arranged as sheets and nest. the cells have round to oval hyperchromatic nucleus with moderate atypia and moderate eosinophilic to clear cytoplasm . stroma shows inflammatory infiltrate and focal myxoid change.,biopsy from right breast.invasive ductal carcinoma.grade 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1701463,carcinoma right breast,right modified radical mastectomy,procedure : mastectomy laterality : right total dimensions : medial lateral 24cm superficial deep 4cm superior inferior 17cmskin ellipse : 13x9cm nipple :normal scar surgical defect : not seentumor : singletumour size : 2.5x2x1.8cm location of tumor : central quadrant margins of tumor : illdefined deep margin : 1.5cm muscle : absent adjacent breast : fibrofatty tissue axillary tail : 9x6x2cmsize of largest node : 2.5x1x0.5cm cut surface is fatty infiltration,sections reveal breast parenchyma harboring a neoplastic lesion arranged in sheets nestsand tubular configuration consisting of round to oval cells exhibiting moderate to marked nuclear pleomorphism and eosinophilic cytoplasm. mitotic figures are discerned. ductal carcinoma in situ high grade is also noted. lymphovascular invasion is identified,right breast right modified radical mastectomy: invasive ductal carcinoma grade iii. modified br score is 8 9.tubule formation: 3nuclear pleomorphism: 3 mitotic figures: 2tumor measures 2.5cm in greatest dimension and is located in the central quadrant. ductal carcinoma in situ presentlymphovascular invasion identifiedperineural invasion not identifiedposterior resection margin is free of tumornipple and areola is unremarkablelymph nodes: 14 lymph nodes metastasis: 2(2 14) . summary : right mrm invasive ductal carcinoma grade iii. lymph nodes: 2 of 14 lymph nodes show metastatic tumor deposits. (2 14)
MR1701483,mass in right breast. carcinoma breast.,right breast mass core biopsy.,received 4 grey white to grey brown linear cores measuring 0.5 to 1cm. entire tissue processed.,section shows linear cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast mass core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson sore is 6(3+2+1). ductal carcinoma in situ of solid and comedo pattern with intermediate nuclear grade is seen.
MR1701499,b) solid cystic multilobulated mass lesion in both breast ( lt gt r) carcinoma breast.,b) left breast mass.,b) received 7 grey white to grey brown linear cores measuring 0.5 to 0.7cm. enter tissue processed.,b) section shows linear cores of breast parenchyma harboring lesion arranged in papillary clusters lined with atypical cells that are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma shows desmoplasia with chronic inflammatory infiltrates.,b) left breast mass:ductal carcinoma in situ with comedonecrosis and papillary neoplasm.suggest excised biopsy.
MR1701514,carcinoma right breast.,biopsy from ulcerated wound right breast.,received single grey white to grey brown soft tissue bits altogether measures 1.2x0.7x0.3 cm. entire tissue processed.,section shows skin with epidermis showing pseudoepitheliomatous hyperplasia with underlying stroma infiltrated by a cellular lesion arranged as diffuse sheets. the cells have round to oval vesicular nucleoli with moderate to marked atypia prominent nucleoli and moderate cytoplasm. stroma shows dense inflammatory infiltrate.,biopsy from ulcerated wound right breast.invasive carcinoma nos grade 3.mbr score is 8 9.tubule formation 3.nuclear pleomorphism 3.mitosis 2.
MR1701539,mass in left breast carcinoma breast.,left breast core biopsy.,received 3 grey white linear cores measuring 1.2 to 1.5. entire tissue processed.,section show cores of tissue with a lesion arranged is vague tubules and sheets. individual cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm stroma show desmoplasia and hyalinisation.,left breast core biopsy:invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1701580,mass in left breast carcinoma breast.,biopsy from left breast.,received 4 grey white to grey brown linear core measuring 0.8 to 1.0cm. entire tissue processed.,section shows linear cores of tissue infiltrated by a lesion arranged as diffuse sheets and tubules. the cells have round to oval hyperchromatic pleomorphic nucleus and scanty cytoplasm. areas of necrosis present . stroma shows focal inflammatory infiltrate.,biopsy from left breast:invasive ductal carcinoma grade2.mbr score in 7 9.tubule formation 3nuclear atypia 2mitosis 2areas of necrosis seen.
MR1701588,mass in left breast carcinoma breast.,biopsy from left breast.,received 3 slide linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows linear cores of tissue harboring an infiltrate lesion arranged as tubules sheets and cords. the cells have round to oval hyperchromatic markedly pleomorphic nucleus and scanty to moderate cytoplasm. stroma shows inflammatory infiltrate and areas of fibrosis.,biopsy from left breast:invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9tubule formation 2nuclear pleomorphism 3.mitosis 2.
MR1701606,left breast lump carcinoma left breast,left breast lump core biopsy.,received 6 grey white linear cores measured 0.5 to 1.2cm. entire tissue processed.,section shows cores of tissue with few dilutes lined by cuboidal epithelial cells. stroma shows spindle cells with few lymphocytes.,left breast lump core biopsy:suggestive of proliferative breast disease. fibroadenoma phyllodes tumorsuggest excision of the lump for further confirmation.
MR1701632,mass in left breast carcinoma breast.,left breast mass core biopsy.,received 3 grey white to grey brown linear cores measured 0.3 to 1.2cm. entire tissue processed.,section shows tumor cells in tubules cords and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy:invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1701657,solid cystic lesion in right breast carcinoma breast.,biopsy from right breast.,received 3 grey white to grey brown linear cores 0.5 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma exhibiting proliferation of glandular structures lined by inner layer of cuboid epithelium and outer myoepithelial cell layer. few glands shows eosinophilic secretions in the lumen and presence of apical snouting. few cystically dilated ducts noted. stroma shows areas of fibrosis hyalinisation and lymphocytic infiltrate.,biopsy from right breast.proliferative breast disease favoring adenosis.the tissue cores submitted show no evidence of invasive malignancykindly correlate with mamographic findings and suggest repeat biopsy if clinically deemed necessary.
MR1701659,mass in left breast carcinoma breast.,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 0.3 to 1cm. entire tissue processed.,section shows linear cores of tissue infiltrated by cords and nests of round to oval cells with hyperchromatic pleomorphic nucleus and scanty cytoplasm. stroma shows areas of fibrosis elastosis and hyalinisation.,biopsy form left breast:invasive ductal carcinoma.modified bloom richardson score 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1701662,carcinoma right breast,a) excised right axillary lymph nodes sentinel lymph node biopsyb) right breast lump wide excisionc) revised lateral margind) revised superior margin,a) received fibrofatty tissue measures 3.5x2x1cm largest lymph node measures 1x0.5x0.5cm cut surfaceis dye stainedb) received lumpectomy specimen measures 8x6x4cm skin ellipse measures 3x0.8cm.serial sectioning shows an ill defined grey white lesion measures 2x2x1.8cmlocated at the following distances from the respective margins:superior margin 1cminferior margin 2cmmedial margin 1.5cmlateral margin 1cmdeep margin 1cm c) received fibrofatty tissue measures 7.5x3x0.5cmd) received fibrofatty tissue with fibrotic nodule measures 3.5x1.5x1cm fibrotic nodule measures 1.5x1x0.5cmdistance of the fibrotic nodule from the ink margin 0.7cm,b) section shows breast parenchyma infiltrated by a lesion arranged in nests cords and trabeculae comprising of pleomorphic cells with large round to oval vesicular to hyperchromatic nuclei with irregular contours prominentnucleoli and scanty to moderate eosinophilic cytoplasm. brisk mitotic activity noted 1 2 hpf. ductal carcinoma in situ is identified with comedonecrosis. stroma shows extensive desmoplasia and fibrosis. lymphovascular invasionis identified. extensive areas of necrosis noted,a) excised right axillary lymph nodes sentinel lymph node biopsy:5 lymph nodes isolated all are free of tumor ( 0 5)b) right breast lump wide excision:invasive ductal carcinoma grade iiimbr score 8 9tubule formation 3nuclear pleomorphism 3mitotic figures 2tumor is located in upper outer quadranttumor measures 2cm in the greatest dimensionsuperior inferior medial and deep margins are free of tumorlateral margins is involved by tumorductal carcinoma in situ is identified comedonecrosislymphovascular and perineural invasion is not identifiedc) revised lateral margin: free of tumord) revised superior margin: free of tumorpathological staging:pt2n0
MR1701678,left breast mass,left breast mass core biopsy.,received 4 grey white to grey brown linear cores measured 0.2 to 1cm. entire tissue processed.,section shows breast parenchyma harboring a neoplastic lesion arranged in nests trabeculae and focal tubular pattern. cells are pleomorphic with scanty cytoplasm and round to oval hyperchromatic nuclei with prominent nucleoli. stroma shows desmoplasia.,left breast mass core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1701704,right breast mass carcinoma right breast.,right breast core biopsy.,received 4 grey white to grey brown linear cores measuring 0.5 to 1cm. entire tissue processed.,section shows tumor cells in diffuses sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6( 3+2+1) .
MR1701715,mass in left breast carcinoma breast.,biopsy from left breast.,received 3 grey white grey brown linear cores measuring 0.8 to 1cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged as cords and nest of cells with round to oval hyperchromatic pleomorphic nucleus and scanty to moderate cytoplasm stroma shows fibrosis and hyalinisation.,biopsy from left breast:invasive ductal carcinoma grade 2tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1701727,mass in right breast carcinoma breast,biopsy from right breast,received 3 grey white to grey brown linear cores measured 5 to 1cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged as cords trabeculae and tubules. the cells have round to oval hyperchromatic pleomorphic nucleus and scanty to moderate cytoplasm. stroma shows fibrosis. hyalinisation and lymphocytic infiltrate.,biopsy from right breastinvasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation 3nuclear pleomorphism 2mitosis 2 7 9
MR1701733,mass in left breast neoplastic,left breast core biopsy.,received 4 grey whit to grey brown linear cores measuring 0.3 to 1cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests and cords individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1701736,mass in right breast carcinoma breast.,biopsy from right breast.,received 3 grey white to grey brown linear cores measuring 0.8 to cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a lesion arranged as cords tubules and nests. the cells have round to oval hyperchromatic nucleus with moderate atypia and scanty cytoplasm. areas of necrosis noted. stroma shows focal inflammatory infiltrate and areas of fibrosis ductal carcinoma in situ high grade solid type with comedonecrosis seen.,biopsy from right breast.invasive ductal carcinoma grade 2 modified bloom richardson score 6 9tubule formation 2nuclear pleomorphism 2mitosis 2.ductal carcinoma in situ with comedonecrosis present .
MR1701785,right breast lump fibroadenoma carcinoma right breast.,biopsy from right breast lump.,received multiple grey white to grey brown linear cores measuring 0.2 to 0.6. entire tissue processed.,section shows linear cores of breast parenchyma exhibiting abundant fibrocollagenous stroma and few glands lined by linear cuboidal epithelium and outer myoepithelial cell layer . occasional cleft like glandular space noted. keratin flakes noted.,biopsy from breast lump:suggestive of epidermoid cyst.no evidence of malignancy in the material submitted .
MR1701804,left breast lump carcinoma left breast.,biopsy of left breast lump.,received 3 grey white to grey brown linear cores measuring 1 to 1.3cm. entire tissue processed,section shows linear cores of tissue harboring a lesion arranged as cords nests and sheets. the cells have round to oval hyperchromatic nucleus with moderate atypia and scanty cytoplasm. areas of necrosis present. stroma shows fibrosis and myxoid change.,biopsy of left breast lump.invasive ductal carcinoma grade 2modified bloom richardson score 7 9tubule formation 3nuclear atypia 2mitosis 2
MR1701821,right breast lump carcinoma right breast.,biopsy of right breast.,received 3 grey white to grey brown cores measuring 0.6 to 1.0cm. entire tissue processed.,section shows linear cores of tissue harboring a cellular lesion arranged as crowded tubules cords and nests. the cells have round to oval hyperchromatic moderately pleomorphic nucleus and scanty to moderate cytoplasm stroma shows inflammatory infiltrate.,biopsy of right breast:invasive ductal carcinoma grade 2.modified bloom richardson score 6 9.tubule formation 2nuclear pleomorphism 2mitosis 2.
MR1701842,left breast lump carcinoma left breast.,biopsy from left breast lump,received 3 grey white to grey brown linear cores measures 0.5 to 1.0cm. entire tissue processed.,sections show multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in nests sheets and tubules lesion comprising of round to oval cells having moderately pleomorphic hyperchromatic nuclei desmoplasia lymphocytic infiltrate. mitotic figures 6 7 hpf. ductal carcinoma in situ with comedo necrosis present. areas of haemorrhage noted.,right breast lump biopsy:invasive ductal carcinoma grade ii.modified bloom richardson score is 6 9.tubule formation :2nuclear pleomorphism :2mitotic figures :2 6 9
MR1701851,left carcinoma breast lung carcinoma left breast.,left breast core biopsy.,received 4 grey white to grey brown linear cores measures 0.7 to 1.0 cm. entire tissue processed.,section shows neoplastic lesion arranged in tubules cords and sheets. individual cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows ductal carcinoma in situ component.,left breast biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is7(3+2+2). ducal carcinoma in situ of cribriform comedo pattern with intermediate nuclear grade seen.
MR1701921,mass in right breast carcinoma breast.,right breast core biopsy.,received 4 grey white to grey brown linear core measuring 0.5 to 1.0cm. entire tissue processed.,section show linear of tissue with and lesion arranged in islands and sheets. individual cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm stroma show hyalinisation and scattered stroma cells. few dilated blood vessels seen.,right breast core biopsy:suggestive of invasive carcinoma nuclear grade ifavoring papillary variant.
MR1701928,right breast birad 4 c lesion.,right breast mass core biopsy.,received 4 grey white to grey brown linear core measuring 0.6 to 1.0cm. entire tissue processed.,section show linear cores of breast parenchyma with a neoplasm lesion arranged in vague tubules and sheets. individual cells have round to oval hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. stroma shows desmoplasia hyalinisation and inflammatory cells consisting of lymphocytes few plasma cells. areas of necrosis seen.,right breast mass core biopsy.invasive ductal carcinoma grade iimodified bloom richardson score (3+2+2) 7 9.ares of necrosis seen.
MR1701932,left breast mass.,left breast mass core biopsy.,received 7 grey white to grey brown linear core measuring 0.7 to 1.0cm. entire tissue processed.,section from the linear cores shows a neoplastic lesion arranged in sheets cells are highly pleomorphic with scanty cytoplasm round to oval hyperchromatic nuclei with prominent nucleoli brisk mitosis noted. stroma shows lymphoplasmacytic infiltration.,left breast mass core biopsy:poorly differentiated malignancy.the possibility of poorly differentiated carcinoma is considered.suggest ihc for confirmation.
MR1701982,core biopsy ductal carcinoma in situ.,biopsy from wide excision of left breast lump.,received in : formalin.procedure : wide excisionlaterality : left breast.lumpspecimen size:medial lateral :9cmsuperficial deep : 6cmsuper inferior : 4cmskin dimensions : 8x4.5cm.skin abnormalities : absentlesion : grey white area : approximately 1 cm in largest dimensiodistance of lesion from marginssuperior margin : 1.5cminferior margin : 2.0cmmedial margin : 1.6cmlateral margin : 2.5cmdeep margin : 0.5cm,multiple section reveal breast parenchyma exhibiting neoplastic proliferation of ductal epithelial cells in solid cribriform and comedo patterns demonstrating moderate nuclear pleomorphism and foci of necrosis. small islands of cells suspicious of microinvasion are seen.,wide excision of left breast lump:ductal carcinoma in situ high gradesmall foci suggestive of invasion.suggest ihctumor size : 0.8x0.6x0.6cm.lymphovascular invasion and perineural invasion : not identified.margins:superior margin : free of tumorinferior margin : free of tumormedial margin : free of tumorlateral margin : free of tumordeep margin : free of tumorskin : free of tumor
MR1701995,right breast mass.,right breast core biopsy.,received 3 grey white linear cores measuring 0.8 to 1cm. entire tissue processed.,section shows linear cores of tissue with a focus showing cells arranged in cords. individual cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows hyalinisation.,right breast core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6 ( 3+2+1).
MR1702000,carcinoma breast right post op,excision biopsy,received already grossed specimen in bit altogether measured 5x4x1.3cm.,multiple fragmented bits show tumor composed of pleomorphic cells with hyperchromatic nucleus and eosinophilic cytoplasmtubular formation lt 10 3nuclear pleomorphism 2mitotic figures 8 10 2 modified bloom richardson 7 9 lymphovascular invasion indeterminate,invasive ductal carcinoma nuclear grade iinote: resected margins and size of the tumor cannot be commented as already the lump is grossed.
MR1702022,lump right breast.,right breast biopsy,received 9 grey white to grey brown linear cores measures 0.8 to 1.0cm. entire tissue processed.,section shows cores of breast parenchyma harboring a lesion arranged in nests cords and trabeculae. cells are pleomorphic with round to oval hyperchromatic to vesicular nucleus prominent nucleoli and moderate amount of eosinophilic to pale granular cytoplasm. brisk mitotic activity noted. stroma shows fibrosis and hyalinisation along with lymphoplasmacytic infiltrates. focal areas of calcification seen. areas of necrosis seen.,right breast biopsy:invasive carcinoma grade 3modified bloom richardson score is 8 9.pleomorphism:2mitosis:3tubule formation:3
MR1702060,mass in right breast carcinoma breast.,right breast mass.,received 3 grey white to grey brown linear cores measures 0.5x to 1cm. entire tissue processed.,section shows linear cores of parenchyma harboring infiltrating lesion arranged in tubules nests cords lesion comprising of round to oval cells having moderate pleomorphic hyperchromatic nuclei and scant cytoplasm. adjacent stroma shows desmoplasia lymphocytic infiltrate. mitotic figures 6 8 10hpf. areas of hemorrhage noted.,right breast mass biopsy:invasive ductal carcinoma grade 2tubule formation 2nuclear pleomorphism 2mitotic figures 2
MR1702066,left breast mass.,left breast mass,received 4 grey white to grey brown linear cores measures 0.8 to 1.0cm. entire tissue processed,section sows cores of breast tissue infiltrated by a lesion arranged in nests islands and cords comprising of atypical cells with moderately pleomorphic round to oval elongated hyperchromatic nuclei inconspicuous nucleoli and moderate to abundant eosinophilic to clear cytoplasm. numerous signet ring cell are noted. stroma fibrosis and hyalinisation. focal areas of necrosis seen . mitotic figures discerned.,left breast mass:invasive ductal carcinoma grade 2modified bloom richardson score is 3+2+2 7 9
MR1702068,known case of carcinoma right breast post mastectomy.,biopsy from pectoral nodal mass.,received 6 grey white linear cores measuring 0.5 to 1cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged as cords nests and tubules. the cells have round to oval hyperchromatic nucleus with moderate atypia and moderate cytoplasm. intervening stroma shows inflammatory infiltrate.,biopsy from right pectoral mass.invasive carcinoma of ductal origin suggestive of recurrence in a known case of carcinoma right breast.
MR1702070,lump in right breast.,right breast right modified radical mastectomy.,procedure : mastectomy mrm. laterality : right.total dimensions : medial to lateral : 22cm. superficial to deep : 7cm. superior inferior :22cm.skin ellipse : 16 x 9 cm. nipple :normal scar surgical defect :not seen.tumor : single.tumour size : 4.5 x 3 x 2.5 cm. location of tumor : lower outer quadrant.margins of tumor : ill defined. deep margin : 2 cm.muscle : absent adjacent breast : fibrofatty. axillary tail : 5 x 5 x 4 cm.total number of nodes : 17size of largest node : 1.5 x 1 x 1 cm. cut surface unremarkable.representative sections are submitted.,section shows tumor cells in diffuse sheets and nest. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular invasion is identified. perineural invasion is not identified.,right breast right modified radical mastectomy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). tumor is unifocal and is located in the lower outer quadrant. tumor measures 4.5 cm in greatest dimension. lymphovascular invasion is identified. perineural invasion is not identified. ductal carcinoma in situ component is not seen. nipple and areolar are free of tumor. posterior resection margin is free of tumor.lymph nodes :nineteen lymph nodes are identified negative for malignancy (0 19).pathological stage : pt2n0
MR1702103,mass in right breast carcinoma breast,right breast core biopsy.,received 5 grey white to grey brown linear cores measuring 0.3 to 0.8cm. entire tissue processed.,section show fragmented biopsy showing breast parenchyma with tumour cells in sheets and nests lying in pools of mucin. individual cells have round to oval basally placed dark nuclei and moderate amount of cytoplasm with few showing cytoplasmic vacuole.,right breast core biopsy:invasive carcinoma with mucinous component grade 2. modified bloom richardson score is 6(3+2+1).
MR1702118,right breast lump,right breast core breast.,received 3 grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue processed.,section linear cores showing a neoplastic lesion arranged in cords and sheets . individual cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows hyalinisation.,right breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score 6(3+2+1).
MR1702136,left breast mass,biopsy from left breast mass,received multiple grey white to grey brown linear cores measures 0.5 to 1.0cm. entire tissue is processed,section studied shows four linear cores showing a lesion arranged in cords nests and aggregates.the neoplastic cells show moderate nuclear pleomorphism with hyperchromatic nuclei and scant cytoplasm. mitotic figures are discerned. stroma shows desmoplasia and also seen are seperate fragments showing hyalinization. areas of necrosis and calcification noted.,biopsy from left breast mass:invasive carcinoma grade iitubule formation 3nuclear pleomorphism 2mitotic figures 2 mbr score 7 9
MR1702155,mass in right breast carcinoma breast,right breast mass,received 3 grey white to grey brown linear cores measures 0.8 to 15cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring infiltrating lesion arranged in sheets nests lesion comprising of round to oval cells having markedly pleomorphism. adjacent stroma shows desmoplasia lymphoplasmacytic infiltrate mitotic figures 6 8 10hpf. areas of necrosis noted.,right breast mass biopsy:invasive ductal carcinoma grade 3tubule formation 3nuclear pleomorphism 3mitosis 2areas of necrosis seen.
MR1702158,right breast lump lesion,biopsy from right breast.,received 3 grey white to grey brown linear cores measuring 0.8 to 1cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged as nests tubules and sheets of cells with round to oval hyperchromatic nucleus with moderate atypia and scanty to moderate cytoplasm. intervening lymphoplasmacytic infiltrate and areas of necrosis noted.,biopsy from right breast:invasive ductal carcinoma grade 2moderate bloom richardson score is 6 9tubule formation 2 nuclear pleomorphism 2mitosis 2
MR1702191,mass in left breast carcinoma breast.,left breast core biopsy.,received 3 grey white to grey brown linear cores measuring 0.8 to 1cm. entire tissue processed.,section show linear cores of breast parenchyma with lesion arranged in tubules and sheets. individual cells have pleomorphic round to oval nuclei and moderate amount of cytoplasm. stroma show fibrosis inflammatory cells consisting of mainly lymphocytes. areas of necrosis noted.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(2+2+1).
MR1702199,lump in left breast,a) lumpectomy wide excisionb) sentinel lymph nodesc) axillary clearance,a) lumpectomy wide excision:received unoriented fibrofatty tissue measures 6.2x5x2.8cm skin ellipse measures 2x0.3cmskin surface is unremarkable on serial sectioning shows an illdefined relatively well circumscribedlesion measures 1.5x1.3x1.3cm.located at the following distances from the respective margins: superior margin 3cminferior margin 0.7cmmedial margin 2.5cmlateral margin 1cmdeep margin 1cmb) sentinel lymph nodes:received single unoriented fibrofatty tissue measures 1.5x1x0.5cm. isolated single lymph nodes measures 0.8x0.3x0.3cm.c) axillary clearance:received fibrofatty tissue measures 9x7x2cm largest lymph node measures 2x1x0.7cm isolated 15 nodes,a) lumpectomy wide excision:tumor bed: tumor is composed of pleomorphic oval to polyhedral cells with hyperchromatic nucleus and scantyeosinophilic cytoplasm.invasive ductal carcinomagrade tubule formation lt 10 3nuclear pleomorphism 8 10 2mitotic figures 2 mbr score 7 9 nuclear grade iiductal carcinoma in situ is not presentlymphovascular invasion not presentperineural invasion not presentresected margins: superior margin free of tumorinferior margin free of tumormedial margin free of tumorlateral margin free of tumordeep margin shows usual ductal hyperplasia free of tumorb) sentinel lymph nodes:one nodes shows reactive hyperplasia no deposits of tumorc) axillary clearance:15 nodes no deposits of tumor,a) lumpectomy wide excision b) sentinel lymph nodes amp c) axillary clearance : invasive ductal carcinomamaximum dimension of tumor is 1.5x1.3x1.3cmductal carcinoma in situ not presentlymphovascular invasion not presentall resected margins are free of tumorsentinel lymph nodes one node no deposits of tumoraxillary lymph nodes 15 nodes no deposits of tumorpathological stage pt1n0
MR1702209,mass in right breast carcinoma breast,right breast,received 4 grey white to grey brown brown linear cores measuring 1 to .1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a lesion arranged as cords and tubules. the cells have round to oval hyperchromatic pleomorphic nucleus with scanty cytoplasm. stroma shows inflammatory infiltrate and myxoid change,biopsy from right breast:invasive ductal carcinoma. grade 2.modified bloom richardson score is 7 9tubule formation 3nuclear pleomorphism 2mitosis 2
MR1702260,mass in right breast carcinoma breast,biopsy from right breast.,received 3 grey white to grey brown linear cores measured 1.2 to 1.4cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast mass core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1702287,right breast lump carcinoma right breast.,right breast biopsy.,received 4 grey white to grey brown linear cores measuring 0.8 to 1.3cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a cellular infiltrating lesion arranged in tubules cords and sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic pleomorphic nucleus with prominent nucleoli in few mitotic figures are discerned. stroma is desmoplastic with areas of hemorrhage and necrosis.,right breast biopsy:invasive ductal carcinoma grade 2.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1702319,mass in left breast carcinoma breast.,left breast core biopsy.,received 4 grey white to grey brown linear cores measured 1.2 to 1.5cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. few large bizarre cells are seen. occasional abnormal mitosis is seen.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+3+1).
MR1702371,lump in right breast,lumpectomy,a) received two separate fibrofatty tissue with same container larger one measures 3.5x2.5x1cmcut surface shows an illdefined grey white fibrotic area measures 3.0x2.5x1cm few dilated areaslocated at the following distances from the respective margin:superior margin 0.2cminferior margin 0.4cmmedial margin 0.4cmlateral margin 0.8cmdeep margin 0.1cmb) received fibrofatty tissue measures 2x1x0.3cm,large mass. multiple section shows dilated ducts are present lined with ductal epithelial cells with outer myoepithelial cells. in other areas ducts show proliferation of cells with stratification and multilayering there is no atypia of cells. scattered ducts are present showing adenosis. stroma consists of spindle cells.there is no evidence of malignancy. small mass shows adenosis with fibrocystic changes in the ducts.,lumpectomy:epithelial hyperplasia.adenosisfibrocystic diseaseno evidence of invasive carcinoma
MR1702377,right breast mass.,biopsy from right breast mass.,received 4 grey white linear cores measures 0.4 to 0.8. entire tissue processed.,section shows linear cores of breast parenchyma showing infiltrating lesion arranged in diffuse sheets and nests comprising of round to oval cells having markedly pleomorphic hyperchromatic nuclei and scant cytoplasm. adjacent stroma shows desmoplasia and lymphocytic infiltrate. brisk mitotic activity noted. areas of hemorrhage and necrosis noted.,right breast mass biopsy invasive ductal carcinoma grade iii.mbr score 8 9.tubule formation 3.nuclear pleomorphism 3.mitotic figures 2.
MR1702381,left breast lump carcinoma left breast.,biopsy from left breast lump.,received 4 grey white linear cores 0.5 to 1cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion composed of sheets and nest of ovoid cells with hyperchromatic nucleus moderate atypia and moderate cytoplasm. stroma shows focal areas of necrosis and lymphocytic infiltrate.,biopsy of left breast lump.invasive ductal carcinoma grade 3.modified bloom richardson score 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 1areas of necrosis.
MR1702399,right breast mass.,biopsy from right breast mass.,received 4 grey white linear cores measures 0.5 cm to 1.5 cm. entire tissue processed.,section show linear cores of breast parenchyma harboring lesion arranged in tubules cords and nests. cells are round to oval having moderately pleomorphic hyperchromatic nuclei and moderate cytoplasm. adjacent stroma shows extensive areas of desmoplasia sclerosis. mitotic figures 3 4 10 hpf.,right breast mass biopsy:invasive ductal carcinoma grade 2.mbr score 6 9.tubule formation 3.nuclear pleomorphism 2mitotic figures 1.
MR1702408,left breast mass.,biopsy from left breast.,received 4 grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords trabacular tubules and in sheets. the cells are round to oval exhibiting nuclear pleomorphism with hyperchromatic nuclei and moderate cytoplasm. desmoplastic hyalinised stroma seen.,left breast biopsy features suggestive of invasive carcinoma.mbr score 6 9 grade ii.tubule formation 3.pleomorphism 2.mitoti activity 1. 6 9
MR1702416,large right breast lump carcinoma right breast,right breast lump,received 4 grey white to grey brown linear cores measures 0.5 to 1cm. entire tissue processed,section shows linear cores of tissue harboring a lesion arranged as cords nests and tubules. the cells have round to oval hyperchromatic nucleus with moderate atypia and scanty to moderate cytoplasm. stroma shows focal fibrosis.,right breast lump biopsy:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9tubule formation 2nuclear pleoomorphism 2mitosis 2
MR1702423,left breast mass.,biopsy from left breast mass.,received 9 grey white to grey bro2wn linear cores measures 0.3 to 1cm. entire tissue processed.,section shows cores of breast parenchyma infiltrated by a lesion arranged in diffuse sheets cores and islands. cells are large with pleomorphic round to oval hyperchromatic nuclei with irregular contours some with prominent nucleoli and moderate cytoplasm .stroma shows desmoplasia and lymphoplasmocytic infiltrate. few large bizarre cells are also seen. mitotic figures discerned.,left breast mass biopsy invasive ductal carcinoma grade 3.modified bloom richardson score (3+3+2) 8 9.
MR1702456,case of carcinoma breast multiple liver space occupy lesions,biopsy from liver lesion,received 3 grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue processed.,linear cores of tissue exhibiting a neoplastic lesion arranged in nests and tubular configuration demonstrating mild to moderate nuclear pleomorphism and eosinophilic cytoplasm amidst fibrocollagenous stroma.,biopsy from liver lesion:suggestive of metastatic carcinoma in a known case of carcinoma breast.report on ihc to follow.
MR1702463,left breast mass.,biopsy from left breast.,received 4 grey white to grey brown linear cores measuring 0.8 to 1cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged as sheets and nests of cells with round to oval hyperchromatic nucleus moderate atypia and scanty cytoplasm. mitotic figures discerned. solid type ductal carcinoma in situ present. areas of necrosis noted.,biopsy from left breast:invasive ductal carcinoma grade 2.modified bloom richardson score 7 9tubule formation 3nuclear pleomorphism 2mitosis 2
MR1702483,b) left breast mass 12 clock,b) biopsy from left breast mass at 12 0 clock position.,received 3 grey white to grey brown linear cores measuring 1 to 1.2cm. entire tissue processed.,b) biopsy shows linear cores of tissue harboring a lesion arranged as nests sheets of ovoid cells with hyperchromatic. mitotic figures discerned. stroma shows fibrosis and hyalinisation.,b) biopsy from left breast mass at 12 0 clock position.invasive ductal carcinoma grade 2modified bloom richardson score 6 9tubule formatiion 2nuclear pleomorphism 2mitosis 2
MR1702529,right breast mass,right breast mass biopsy,received 3 grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section from breast shows linear cores of tissue showing extensive hyalinisation with scattered clusters of atypical cells. the cells exhibit marked pleomorphism with hyperchromatic nuclei and scant cytoplasm.,right breast mass biopsy:suggestive of invasive ductal carcinoma grade 2 modified bloom richardson score is 6 9tubule formation : 3pleomorphism : 2mitosis :1 6 9
MR1702571,right breast mass,right breast mass core biopsy.,received 3 grey white to grey brown linear cores measures 0.3 to 0.7cm. entire tissue processed.,section shows tumor cells in nests cores and tubules . individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast mass core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1702606,right breast mass,right breast mass biopsy,received 3 grey white to grey brown linear cores measures 0.2 to 1.4 cm. entire tissue processed.,sections show linear cores of breast parenchyma infiltrated by a lesion arranged in nests and cords comprising of large cells with pleomorphic round to oval vesicular to hyperchromatic nuclei few with prominent nucleoli and moderate to abundant eosinophilic cytoplasm. stroma shows extensive desmoplasia along with lymphocytic aggregates. focally comedo necrosis type ductal carcinoma in situ seen.,right breast mass biopsy:invasive carcinoma grade 2modified bloom richardson score is 6 9 (3+2+2).ductal carcinoma in situ with comedo necrosis noted.
MR1702626,left breast mass.,left breast mass biopsy.,received multiple grey white to grey brown linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in nests islands and tubules cells are round to oval with moderately pleomorphic hyperchromatic nuclei and moderate cytoplasm. adjacent stroma shows desmoplasia and lymphocytic infiltration. mitotic figures 5 6 10hpf,left breast mass biopsy.invasive ductal carcinoma grade ii modified bloom richardson score is 7 9tubule formation :3nuclear pleomorphism : 2mitotic figures : 2
MR1702630,right breast lump carcinoma right breast.,biopsy from right breast,received multiple grey white to grey brown linear cores 1.6 to 1.8cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged as nests cords and tubules. the cells have round to oval hyperchromatic nucleus exhibiting moderate nuclear atypia and moderate eosinophilic to pale cytoplasm. mitotic figures discerned. stroma shows lymphocytic infiltrate and hyalinisation lymphovascular emboli present.,biopsy from right breast:invasive ducatal carcinoma grade 2modified bloom richardson score 7 9tubule formation 3nuclear pleomorphism 2mitotic 2
MR1702677,left breast mass.,biopsy left breast mass.,received 4 grey white to grey brown linear core measuring 1 to 1.3cm. entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as clusters nests and cords .the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm .areas of necrosis seen.,infiltrating ductal carcinoma biopsy from left breast:modified bloom richardson score is 7 9 grade 2tubule formation : 3nuclear pleomorphism: 2mitotic figures : 2 7 9
MR1702681,right breast lump carcinoma breast.,biopsy from right breast lump,received 4 grey white to grey brown linear cores measures 0.5 to 1.2cm. entire tissue processed.,sections show multiple linear cores of breast parenchyma harboring infiltrating lesion and round to oval having moderately pleomorphic hyperchromatic nuclei scant cytoplasm. adjacent stroma shows desmoplasia mitotic figures 6 7 hpf,right breast lump biopsy:invasive carcinoma with lobular differentiation grade iimodified bloom richardson score is 7 9.tubule formation :3nuclear pleomorphism :2mitotic figures :2 7 9
MR1702682,left breast lump.,left breast lump trucut biopsy.,received multiple linear fragment 0.3 to 0.4cm. entire tissue processed.,section show linear cores of breast parenchyma harboring lesion arranged in tubules nests and papillary fronds lined by round to oval having moderately pleomorphic hyperchromatic nuclei moderate cytoplasm. adjacent stroma shows dense desmoplasia lymphocytic infiltrate figures discerned. areas of myxoid change seen,left breast lump biopsy: papillary lesion atypical ductal hyperplasia with papillary configuration papillary neoplasm suggest repeat larger biopsy to rule out invasive carcinoma
MR1702687,case of left breast carcinoma,a) left breast lumpectomyb) revised deep marginc) left axillary dissection,a) received skin covered fibrofatty tissue measures 6.5x6x2.5cm on serial sectioning grey white lesion notedmeasuring 1.6x1.5x1.5cm.located at the following distances from the respective margins:superior margin 1cminferior margin 1cmmedial margin 0.8cmlateral margin 2.6cmskin ellipse measures 5x1cm.b) received fibrofatty tissue measures 1.2x0.5x0.2cm.c) received fibrofatty tissue measures 8x5x3cm. largest lymph node measures 3x1.5x1cm. cut surface show fatty infiltration.,a) breast conservative surgery wide excision.tumor tumor consists of pleomorphic cells with hyperchromatic nucleus with eosinophilic cytoplasm.invasive ductal carcinoma.grade tubule formation 3. nuclear pleomorphism 2. mitotic figures 2. mbr grade 7 9. nuclear grade ii.ductal carcinoma is situ not present.lymphovascular invasion not present.perineural invasion not present.resected margins:superior margin free of tumor.inferior margin free of tumor. medial margin free of tumor. lateral margin free of tumor.b) deep margin shows muscle bundles free of tumor.c) axillary clearance:18 nodes no deposits of tumor.,wide excision breast conservative surgery:invasive ductal carcinoma.maximum dimensions of tumor is 1.6x1.7cm.nuclear grade ii.ductal carcinoma is situ not present.lymphovascular invasion not present.all resected margins are free from the tumor. revised deep resected margin free of tumor.axillary lymph nodes 18 nodes no deposits of tumor.pathological grade pt1n0.
MR1702693,carcinoma left breast,a) sentinel lymph node biopsyb) left modified radical mastectomy and axillary lymph node dissection(level 1 2),a) received 3 bits fibrofatty tissue measures 2x2x1.5cm largest lymph node measures 1x1x1cm cut surface shows fatty infiltration. isolated 12 lymph nodesb)procedure : modified radical mastectomy laterality : left total dimensions : medial lateral 22cm superficial deep 3cm superior inferior 19cmskin ellipse : 14x7cm nipple :normal scar surgical defect : not seentumor : single tumour size : 2.2x2x1.5cm. location of tumor : upper inner quadrant margins of tumor : illdefined deep margin : 2cmmuscle : absent adjacent breast : fibrofatty axillary tail : 6x4x2.8cm,a) sentinel lymph node biopsy:sentinel lymph nodes 2 nodes show metastatic deposits of tumor out of 12 nodesb) left breast left modified radical mastectomy: invasive ductal carcinoma grade ii. modified br score is 7 9.tubule formation: 3nuclear pleomorphism: 2 mitotic figures: 2tumor measures 2.2cm in greatest dimension and is located in the upper inner quadrant. ductal carcinoma in situ present low grade solid type measures 0.5cm lymphovascular invasion presentperineural invasion presentposterior resection margin is free of tumornipple and areola is unremarkablemastectomy specimen lymph nodes: 13 lymph nodes no metastatic deposits of tumor out of 13 nodes.,left breast mrm invasive ductal carcinoma residual tumor present grade iilymph nodes from mastectomy specimen 13 nodes no deposits of tumorsentinel lymph nodes 2 nodes show metastatic deposits of tumor out of 12 nodestotal no. of positive nodes 2 nodes out of 25 nodes
MR1702699,right breast lump carcinoma right breast.,biopsy from right breast lump,received 6 grey white to grey brown linear cores measures 0.4 to 1.0cm. entire tissue processed.,sections show multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in nests sheets and comprising of round to oval cells having moderately pleomorphic hyperchromatic nuclei and moderate cytoplasm. adjacent stroma shows desmoplasia lymphocytic infiltrate. mitotic figures 6 7 hpf. areas of necrosis and calcification noted,right breast biopsy:invasive carcinoma not otherwise specified grade ii.modified bloom richardson score is 6 9.tubule formation :3nuclear pleomorphism :2mitotic figures :1 6 9
MR1702709,left breast lump.,left breast core biopsy.,received 3 grey white to grey brown linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows linear cores of tissue with stroma showing extensive desmoplasia. scattered neoplastic cells arranged in nest and cords seen with cells having pleomorphic round to oval hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy:invasive carcinoma grade iimodified bloom richardson score 6 9 (3+2+1).
MR1702727,carcinoma left breast left breast level iii lesion deposit,left level iii lesion node biopsy,received 5 grey white to to grey brown linear cores measures 0.3 to 0.8cm. entire tissue processed.,section show linear cores of tissue fragments demonstrating spindle cells with eosinophilic cytoplasm. areas show rosettoid formation of cells with myxoid areas. dilated blood vessels are seen.,left level iii lesion node biopsy:suggestive of atypical proliferative lesion.suggest excision biopsy for further confirmation.
MR1702742,carcinoma left breast post lumpectomy,a) wide excision lumpectomyb) sentinel lymph nodesc) revised margin based) left axillary dissection,a) received single skin covered fibrofatty tissue measures 9x7x4cm.skin ellipse measures 4x1.5cm. surface shows a scar measures 2.5cm.on serial sectioning shows a illdefined grey white fibrotic and necrotic lesion measures 2x1.5x1.5cm. located at the following distances from the respective margins:superior margin 1.5cminferior margin 2.5cmmedial margin 2.5cmlateral margin 1.5cmdeep margin 1.5cmb) sentinel lymph nodes :received single fibrofatty tissue altogether measures 4x2.5x2cm. largest lymph node measures 2.5x1.5x1cm. cut surface show fatty infiltration. isolated 4 lymph nodesc) revised margin from the base:received fibrofatty tissue measures 5x3x0.5cm grossly unremarkabled) left axillary dissectionreceived fibrofatty tissue measures 6x4x1.5cm isolated 8lymph nodes,a) wide excision lumpectomy :the section shows fibrosis necrosis lymphocytic infiltration and foreign body giant cellsand granulation tissue.no evidence of residual tumor presentresected margin from the fibrotic areasuperior margin free of tumorinferior margin free of tumormedial margin free of tumorlateral margin free of tumordeep margin free of tumorb) sentinel lymph nodes:4 nodes no deposits of tumorc) revised margin base:fibrofatty tissue and muscle bundle free of tumord) left axillary dissection:8 nodes no deposits of tumor,a) wide excision post lumpectomy:no residual tumor presentareas of fibrosis necrosis and granulation tissueall resected margins are free of tumorb) sentinel lymph nodes: 4 nodes no deposits of tumorc) revised margin base : free of tumord) left axillary dissection: 8 nodes no deposits of tumor
MR1702756,right breast lump carcinoma.,biopsy from right breast.,received 4 grey white to grey brown linear cores 1 to 1.2cm. entire tissue processed.,section shows cores of breast parenchyma showing focal infiltration by a lesion arranged in cores and nests comprising of atypical cells with round to oval moderately pleomorphic hyperchromatic nuclei some with prominent nucleoli irregular nuclear contours and scanty to moderate cytoplasm. stroma shows extensive fibrosis and hyalinisation with focal areas of necrosis.,right breast biopsy invasive ductal carcinoma grade 2.modified bloom richardson score (3+2+1) 6 9.
MR1702780,left breast mass.,biopsy from left breast,received 3 grey white to grey brown linear cores 0.5 to 1cm. entire tissue processed,linear cores of breast tissue infiltrated by a neoplasm arranged as cords tubules and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is elastotic.,biopsy from left breast:infiltrating ductal carcinoma.modified bloom richardson score is 7 9 grade 2tubule formation :3nuclear pleomorphism :2mitotic figures :2 7 9
MR1702806,lump in left breast,a) left breast lumpectomy(frozen section). b) left breast left modified radical mastectomy.,a) received lumpectomy specimen measures 5 x 5 x 3 cm skin ellipse measures 3.5 x 1.5 cm cut surface shows a grey white lesion measuring 2.5 x 2.5 x 1.5 cm distance from closest inked margin 0.5 cmb)procedure : mastectomy laterality : left total dimensions : medial lateral 19cm superficial deep 4.5cm superior inferior 15cmskin ellipse : 15x9cm. nipple :normal scar surgical defect : 5x2cm.lumpectomy cavity : 6.5 x 6 x 3.5 cm location of tumor bed : upper outer quadrant deep margin : 2.5cm muscle : absent adjacent breast : fibrofatty axillary tail : 8 x 7 x 3.5 cmsize of largest node : 2 x 1.5 x 1.0 cm cut surface shows grey white.representative sections are submitted.,section from tumour shows neoplastic lesion arranged in sheets nests and in lobules. individual tumour cells are round to oval highly pleomorphic with vesicular nuclei prominent nucleoli and moderate to abundant eosinophilic cytoplasm. brisk mitotic activity noted. intervening stroma shows lymphoplasmacytic infiltrate.areas of fibrosis hyalinisation noted. ductal carcinoma in situ area with central necrosis noted. lymphovascular invasion is seen. congested blood vessels seen.,a) left breast lumpectomy(frozen section) :invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+2+3). tumor measures 2.5 cm in the greatest dimension lymphovascular invasion is present perineural invasion is present ductal carcinoma in situ of solid and comedo pattern with intermediate nuclear grade is seen. overlying skin is free of tumorb) left breast left modified radical mastectomy(post lumpectomy): no residual tumor is seen. adjacent breast tissue is unremarkable. nipple and areola are free of tumour. posterior resection margin is free of tumour.lymph nodes :one out of twenty lymph nodes shows metastatic tumour deposit(1 20). size of the tumour deposit measures 2.0 cm in greatest dimension. no extranodal extension is seen.pathological stage : pt2n1a
MR1702829,right breast lump carcinoma right breast.,biopsy from right breast,received 3 grey white to grey brown linear cores measures 1.2 to 1.5cm. entire tissue processed.,section shows tumor cells in nests cords and diffuse sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1702868,right breast mass,right breast mass biopsy,received 4 grey white to grey brown linear cores measures 0.5 to 0.7cm. entire tissue processed.,sections show multiple fragments of tissue harboring neoplastic lesion arranged in sheets cords . the cells are round to oval pleomorphic with vesicular nuclei and few showing prominent nucleoli. areas of desmoplasia is noted. there is presence of inflammatory infiltrate composed of lymphocytes plasma cells intermixed with tumor cells. mitosis noted. fibrosis seen.,right breast biopsy:invasive carcinoma no special type grade ii (7 9).tubular formation : 3nuclear pleomorphism : 3mitotic figures :1
MR1702894,right breast lump carcinoma right breast.,right breast lump biopsy.,received 3 grey white to grey brown linear cores measuring 0.8 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a lesion arranged in islands nests with cords comprising of atypical cells with round to oval hyperchromatic pleomorphic nuclei moderate to abundant eosinophilic cytoplasm. mitotic figures discerned. focal areas of necrosis seen. stroma shows desmoplasia with lymphoplasmacytic infiltrate.,right breast lump biopsy:invasive ductal carcinoma grade 2modified bloom richardson : 3+2+2 7 9
MR1702908,mass in right breast right breast carcinoma breast.,right breast mass core biopsy.,received multiple grey white to grey brown linear cores measures 0.8 to 1.4cm.entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast mass core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6( 3+2+1).
MR1702927,left breast mass,left breast mass biopsy,received 3 grey white to grey brown linear cores measures 0.8 to 1.4cm. entire tissue processed.,sections shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in nests cords and cribriform pattern. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned stroma shows desmoplasia with chronic inflammatory infiltrates. areas of hemorrhage and necrosis seen.,left breast mass biopsy:invasive ductal carcinoma no special type grade 2modified bloom richardson score 6 9tubular formation :2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1702948,mass in right breast carcinoma breast.,right breast mass biopsy,received 3 grey white n linear cores measures 1.2 to 1.4cm. entire tissue processed.,sections shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in nests cords having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned stroma shows desmoplasia with chronic inflammatory infiltrates. areas of hemorrhage and necrosis seen.,right breast mass biopsy:invasive ductal carcinoma grade 2modified bloom richardson score 7 9tubular formation :3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1702949,mass in right breast carcinoma breast.,biopsy from right breast,received 4grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section shows hyperplastic ductules and stroma. ductules are lined by cuboidal cells and few are compressed by stroma forming slit like spaces. stroma shows fibrocollagenous tissue with myxoid change and spindle cells. no atypia or mitosis are seen.,right breast mass core biopsy :features are suggestive of proliferative breast disease. fibroadenomasuggest excision of the lump for further confirmation.
MR1702992,right breast mass.,right breast biopsy.,received 4 grey white linear cores measuring 1.2 to 1.4cm. entire tissue processed.,section shows multiple fragments from breast parenchyma showing few clusters of atypical cells arranged in tubules cords. the cells exhibits moderate pleomorphism with vesicular nuclei and prominent nucleoli. extensive areas of fibrosis and desmoplasia are noted.,right breast biopsy :highly suspicious of invasive carcinoma.suggest repeat biopsy as the sample is sparsely cellular
MR1703041,carcinoma left breast s p lumpectomy outside,a) breast conservative surgery post lumpectomyb) axillary clearance,a) breast conservative surgery post lumpectomy:received oriented skin covered fibrofatty tissue altogether measures 6x5x4.5cm skin ellipse measures2.2x1cm. skin surface shows healed scar measures 2cm. on serial sections show illdefined grey white fibrotic lesion measures 1.5x1.5x1cm located at the following distances from the respective margins:superior margin 0.8cminferior margin 2cmmedial margin 2cmlateral margin 1cmdeep margin 1cmb) axillary clearance: received fibrofatty tissue measures 6x5.5x1.5cm largest lymph node measures 1.5x1x0.5cm cut surface shows grey brown. dissected 14 nodes.,a) breast conservative surgery post lumpectomylumpectomy bed: no residual tumor presentareas of necrosis fibrosis and inflammatory cellular infiltrates with foreign body giant cells and granulation tissue post lumpectomy changesresected margins superior margin shows adenosis free of tumorinferior margin free of tumormedial margin free of tumorlateral margin shows adenosis free of tumordeep margin free of tumorb) axillary clearance :14 nodes no deposits of tumor,a) breast conservative surgery post lumpectomy:no residual tumornecrosis fibrosis post lumpectomy changesall resected margins free of tumorb) axillary clearance:14 nodes no deposits of tumor
MR1703050,left breast lump carcinoma breast.,left breast lump.,received 3 grey white linear cores measures 0.8 to 1.2cm. entire tissue processed.,needle core biopsy from left breast lump shows sheets and clusters of pleomorphic cells. the cells show hyperchromatic nucleus prominent nucleoli and eosinophilic cytoplasm. background shows mucin at places.,invasive carcinoma left breast.moderate br scores 8 9 grade 3.pleomorphism 2.tubules 3.mitosis 3. 8 9
MR1703082,large left breast lump carcinoma left breast.,left breast lump core biopsy.,received 3 grey white to grey brown linear cores measuring 1.2 to 1.4cm. entire tissue processed.,section show linear cores of tissue with a lesion arranged is sheets having round to oval hyperchromatic nuclear and moderate amount of cytoplasm also seen are giant cells having round to oval hyperchromatic nuclei and abundant amount of eosinophilic cytoplasm stroma show desmoplasia with scattered inflammatory cells.,left breast lump core biopsy:invasive carcinomaof poorly differentiated origin nuclear grade ii
MR1703085,left breast lesion.,biopsy from left breast lesion.,received 4 greywhite linear cores measuring 0.5 to 0.6cm. entire tissue processed.,section from breast shows linear cores of tissue harboring a neoplastic lesion arranged in cords tubules trabaculae. the cells exhibit moderate pleomorphism with hyperchromatic nuclei and desmoplasia noted.,invasive ductal carcinoma biopsy from left breast.modified br score is 6 9 grade 2.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1703108,known case of carcinoma breast post rx on tamoxifen with increased ett,uterus with bilateral adnexae.,procedure : tah+bsouterus dimensions: midline fundal serosa to ectocervix : 10.5cmmaximum intercornual : 7.5cmmaximum anterior to posterior : 3mcervix dimentions : 4.5x4cmvaginal cuff : presentcervix shape : normal.right ovary : 3.4x2.5x1.2. cut surface follicular cystleft ovary : 5.5x4x2.5cm. cut surface let out brown viscous fluidright fallopian tube : 4cm. fimbrial end identifiedleft fallopian tube : 4cm fimbrial end identifiedright parametrium : 2x2.5x0.3cm.left parametrium : 3x2x0.6cm.endometrium descriptionendometrial thickness : 0.5cm no definite abnormality identified.myometrium descriptionmyometrial depth : anteriorly 1.8cm.left ovary cut surface dark brown thick viscous fluid multilobulated cyst identifiedinner wall is smooth,multiple sections from endometrium show benign endometrial glands and a few dilated glands lined by flattened to cuboidal epitheliumsection from cervix unremarkablesection from right ovary unremarkablesection from fallopian tube and fimbrial end free of tumorsection from parametrium free of tumor.,uterus with bilateral adnexae:benign endometrial polyp with simple hyperplasia with no nuclear atypiamyometrium : unremarkablebilateral ovaries and fallopian tubes : unremarkablebilateal parametrium : unremarkable
MR1703113,left breast lump.,left breast mass core biopsy.,received 3 friable grey white to grey brown linear cores measures 0.5 to 1.2cm. entire tissue processed.,section show linear cores of tissue harboring a neoplastic lesion arranged in sheets few in tubules. individual cells have pleomorphic round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows desmoplasia mitotic figures discerned. area of necrosis noted.,left breast mass core biopsy:invasive carcinoma nst grade iimodified bloom richardson score is 7 9(3+2+2).
MR1703118,right breast mass,biopsy from right breast.,received 3riable grey white to grey brown linear measures 1.2x1x0.6cm. entire tissue processed.,section shows linear cores of tissue showing breast parenchyma with a lesion arranged in cords and sheets. individual cells have pleomorphic round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma show desmoplasia with inflammatory cells. lympho vascular invasion seen.,biopsy from right breast mass:invasive carcinoma nst grade iimodified bloom richardson score is 7 9(3+2+2)lymphovascular invasion is seen.
MR1703137,mass in left breast carcinoma breast.,biopsy from left breast.,received 4 grey white to grey brown linear cores measures 1.0 to 1.2cm. entire tissue processed.,linear core of breast tissue infiltrated by a neoplasm arranged as islands and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. areas of necrosis seen.the intervening stroma is elastatic.,biopsy from left breast:invasive ductal carcinoma modified bloom richardson score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1703150,lump in right breast,a) right breast lumpectomyb) revised lateral margin,a) received lumpectomy specimen measures 7x6x3cm on serial sectioning grey white illdefined areas measures 2.5x2x1.8cm with foci of necrosis.located at the following distances from the respective margins:superior margin 0.3cminferior margin 1cmmedial margin 0.5cmlateral margin 0.2cmdeep margin 0.1cmb) received fibrofatty tissue measures 3x2x1cm one surface is inked,section shows breast parenchyma with neoplastic lesion arranged in cords trabeculae andsheets. the cells are round to oval with vesicular nuclei and prominent nucleoli with eosinophiliccytoplasm. there are presence of extensive ductal carcinoma in situ arranged in solid cribriform pattern and with comedonecrosis.tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9 resected margins : superior margin 0.3cm inked margin is free of tumorinferior margin 0.2cm inked margin is free of tumorlateral margin free of tumordeep margin 0.1cm inked margin is free of tumor,a) right breast lumpectomy:invasive ductal carcinoma grade ii with extensive ductal carcinoma in situ.mbr score 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1invasive carcinoma measures 1cm in greatest dimensionductal carcinoma in situ measures 1.5cm in greatest dimensionperineural invasion and lymphovascular invasion not identifiedresected margins :superior 0.3cmlateral 0.2cmdeep 0.1cm away from tumorall the resected ink margins are free of tumorb) revised lateral margin:few ducts shows ductal carcinoma in situ with comedonecrosisinked margin is free from the tumorsummary:a)right breast wide local excision:maximum dimension of tumor is 2.5cmextensive areas of ductal carcinoma in situ with comedonecrosis consisting 1.5cminvasive ductal carcinoma constituting 1cm grade iilymphovascular and perineural invasion not presentresected margins: superior margin 0.3cmlateral margin 0.2cmdeep margin 0.1cmall the resected ink margins are free of tumorb) revised lateral margin:few ducts shows ductal carcinoma in situ with comedonecrosisinked margin is free from the tumor.
MR1703191,right breast lump .,biopsy from right breast.,received 4 grey white to grey brown linear cores measuring 0.8 to 1.2cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged as nests tubules and cords. the cells have round to oval hyperchromatic nucleus with moderate atypia and scanty to moderate cytoplasm. stroma shows fibrosis lymphovascular invasion seen.,biopsy from right breast:invasive ductal carcinoma grade 2moderate bloom richardson score is 6 9tubule formation 2nuclear pleomorphism 2mitosis 2
MR1703202,right breast lump carcinoma right breast.,biopsy from right breast.,received 4 grey white to grey brown linear cores measures 0.8 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma with numerous lymphoplasmacytic infiltrate found admixed with multinucleated giant cells and epitheloid cells. interpersed are numerous histiocytes and congested blood vessels,right breast lump biopsy:granulomatous mastitis with predominant plasma cells.no evidence of malignancy in the material submitted.
MR1703223,mass in right breast carcinoma breast.,right breast biopsy.,received 3 grey white to grey brown linear cores 1.0 to 1.4cm. entire tissue processed.,section shows multiple linear fragments of tissue harboring a neoplastic lesion arranged in tubules sheets. the cells are round to oval with pleomorphic hyperchromatic nuclei with abundant eosinophilic cytoplasm. mitotic noted. there are also areas of ductal carcinoma in situ with comedonecrosis. intervening stroma shows desmoplasia.,right breast biopsy:suggestive of invasive ductal carcinoma with ductal carcinoma in situ. ( nuclear grade 2).
MR1703224,carcinoma left breast post op left chest wall lesion recurrence.,biopsy from left chest wall lesion,received multiple grey white to grey brown linear cores measures 0.4x0.8cm. entire tissue processed.,section show linear cores of breast parenchyma harboring an infiltrating cellular lesion arranged in tubules and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned . stroma shows desmoplasia with chronic inflammatory infiltrate. areas of hemorrhage and necrosis seen.,biopsy from left chest wall lesion:recurrent invasion carcinoma nst grade 2 in a known case of carcinoma left breast status post opmbr scoretubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1703235,left breast lump carcinoma,a)left breast wide excisionb) left sentinel lymph node biopsyc) left axillary clearance,a)left breast wide excision:received lumpectomy specimen measures 9x8x4cm skin ellipse measures 7.5x3cm cut surface shows illdefined grey white lesion measures 4.5x2.5x1.5cm. located at the following distancesfrom the respective margins:superior margin 1.2cminferior margin 2cmmedial margin 0.5cmlateral margin 2cmdeep margin 1cmb) left sentinel lymph node biopsy:received fibrofatty tissue measures 4x3.5x1.5cm largest lymph node measures 3.3x1.4x1cmcut surface shows grey white to grey brownc) left axillary clearancereceived fibrofatty tissue measures 8x6x2cm largest lymph node measures 2.5x1.5x0.7cm cut surface shows grey white total isolated 17 lymph nodes,a)left breast wide excision:tumor : tumor is composed of pleomorphic cells with hyperchromatic nucleus and scanty cytoplasm. invasive ductal carcinomagrade tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9 ductal carcinoma in situ not presentlymphovascular invasion presentperineural invasion presentresected margins : superior margin free of tumorinferior margin free of tumormedial margin free of tumorlateral margin free of tumordeep margin free of tumorb) left sentinel lymph node biopsy :2 nodes show metastatic deposits of tumor out of 3 nodesc) left axillary clearance16 nodes no deposits of tumor,a)left breast wide excision:invasive ductal carcinoma maximum dimension of tumor is 4.5x2.5x1.5cmnuclear grade iiductal carcinoma in situ not presentlymphovascular invasion not presentperineural invasion presentall resected margin are free of tumorb) left sentinel lymph node biopsy:2 nodes shows metastatic deposits of tumor out of 3 nodesc) left axillary clearance:16 nodes no deposits of tumorpathological stage : pt2n1
MR1703278,incisional biopsy right breast.,incisional biopsy right breast.,received 2 grey white to grey brown soft tissue bits altogether measuring 1.2x0.9x0.5cm. entire tissue processed.,section shows skin with ulceration and underlying stroma harboring a cellular lesion arranged as tubules nests and cords. the cells have round to oval hyperchromatic nucleus with moderate atypia and scanty cytoplasm. intervening stroma shows lymphocytic infiltrate. areas of calcification noted. lymphovascular invasion is seen and overlying skin is ulcerated.,incisional biopsy right breast:invasive ductal carcinoma grade ii.moderate bloom richardson score is 6 9tubule formation 2nuclear atypia 2mitosis 2.
MR1703310,right breast lump carcinoma right breast.,biopsy from right breast.,received 6 grey white to grey brown linear cores measures 0.5 to 1.0cm. entire tissue processed.,section from breast parenchyma shows multiple linear cores harboring a neoplasm lesion arranged in trabeculae cords andsheets exhibiting pleomorphism with round to oval hyperchromatic nuclei and moderate cytoplasm.mitotic figures seen. areas of necrosis seen intervening stroma shows lymphocytic infiltrate.,biopsy right breast.poorly differentiated malignancysuggestive of invasive ductal carcinoma nuclear grade 2.
MR1703319,lump and ulceration over left breast.,incisional biopsy left breast.,received 2 grey white to grey brown soft tissue bits altogether measuring 1.2x0.8x0.6cm. entire tissue processed.,section shows skin with ulceration and underlying stroma harboring a cellular lesion arranged as nests islands and tubules. the cells have round to oval hyperchromatic nucleus moderate to marked atypia. few with prominent nucleoli and scanty cytoplasm. areas of necrosis noted.,incisional biopsy left breast:invasive ductal carcinoma grade 2 modified bloom richardson score is 7 9tubule formation 2 nuclear 3 mitosis 2 7 9
MR1703327,right breast lump carcinoma right breast.,biopsy from right breast.,received 4 grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section from breast parenchyma shows multiple linear cores harboring a lesion arranged in cords sheets. the cells are noted to oval with hyperchromatic nuclei and scant cytoplasm. extensive areas of desmoplasia noted. areas of hemorrhage see.,biopsy from right breast:suggestive of invasive ductal carcinomamodified bloom richardson score is 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitosis :1 6 9
MR1703349,mass in left breast carcinoma breast.,biopsy from left breast.,received multiple grey white linear cores measures 0.8 to 1.2cm. entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as tubules and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,biopsy from left breast:invasive ductal carcinoma modified bloom richardson score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1703368,right breast mass carcinoma breast.,biopsy from right breast mass,received 3 grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in sheets nests and cords. individual cells have hyperchromatic nuclei and amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1703371,right breast mass,biopsy from right breast mass,received 4 grey white to grey brown linear cores measures 1 to 1.4cm. entire tissue processed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1703373,post right mrm.right chest nodules.,biopsy from right chest wall nodule in a known case of carcinoma breast.,received 5 grey white linear cores measures 1.2 to 1.4cm.,linear cores of fibrous tissue infiltrated by a neoplasm arranged in tubular pattern. the lining epithelial cells are cubocolumnar exhibit nuclear hyperchromasia and pseudostratification.,metastatic carcinoma biopsy from right chest wall nodule in a known case of carcinoma breast.
MR1703394,in left breast carcinoma breast.,left breast mass biopsy,received 3 grey white linear cores measures 1.2 to1.4cm. entire tissue processed.,section shows linear cores breast parenchyma with extensive areas of selerosis and occasonal foci of infiltrating lesion arranged in cords and tubules. the cells are atypical ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. areas of hemorrhage and necrosis seen.,left breast mass biopsy:invasive carcinoma with extensive areas of sclerosis grade 1tubule formation formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9
MR1703417,ill defined right breast lump carcinoma right breast.,right breast biopsy,received 4 grey white to grey brown linear cores measures 1.2 to 1.4cm. entire tissue processed.,section shows cores of breast parenchyma harboring a lesion arranged in islands and sheets intermixed with abundant inflammatory infiltrate comprising of lymphocytes and plasma cells. cells are large with pleomorphic round to oval hyperchromatic nuclei with irregular contours some with prominent nucleoli and moderate amount of eosinophilic cytoplasm. stroma shows hyalinisation and fibrosis. mitotic figures seen discerned.,right breast biopsy:invasive ductal carcinoma grade 2modified bloom richardson score is 3+2+2 7 9
MR1703425,birads v lesion in left breast.,left breast lump biopsy.,received 3 grey white linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in nests tubules and cores. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few .stroma shows extensive desmoplasia with chronic inflammatory infiltrates.,left breast lump biopsy:invasive carcinoma nst grade itubule formation : 2 nuclear pleomorphism: 2mitotic figures : 1 5 9
MR1703426,known case of carcinoma left breast underwent mrm in 2013. received adjuvant chemotherapy and presently on aromatase inhibitor. now with left chest wall recurrence4 and lung metastatic.,left chest wall nodule excision biopsy ( carcinoma left breast post op chemo),received fibrofatty tissue measures 2.5 x 2 x 1.5 cm. cut surface shows an ill defined lesion with mucinous areas measures 1x1x1cm.distance from nearest inked surface is lt 0.1cm,section shows tumor cells in tubules and nests lying in pools of extracellular mucin and moderate amount of cytoplasm.,left chest wall nodule excision biopsy(carcinoma left breast post op chemo) :positive for malignancy.suggestive of mucinous carcinoma in a known and treated case of carcinoma breast.
MR1703441,mass in left breast carcinoma left breast.,biopsy from left breast,received 3 grey white linear cores measures 1 to 0.5cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm. few extracellular pools of mucin are seen.,left breast mass core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1703447,mass in right breast carcinoma breast,biopsy from right breast mass,received 4 grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue processed.,sections show linear cores of breast parenchyma harboring an infiltrating lesion arranged in sheets and acini. the cells are ovoid having moderate amount of cytoplasm. hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma shows desmoplasia with chronic inflammatory infiltrate. areas of hemorrhage are seen.,biopsy from right breast mass:invasive ductal carcinoma grade 1(5 9)modified bloom richardson score is 5 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9
MR1703461,known case of carcinoma breast.,chest wall nodule. excision (post mrm right breast.),received fibrofatty tissue measures 2 x 2 x 1 cm. entire tissue processed.,section shows tissue covered with stratified squamous epithelium. stroma shows fibrocollagenous tissue with lymphocytes and congested capillaries. no atypia is seen.,chest wall nodule. excision (post mrm right breast):shows features of chronic non specific inflammation.negative for malignancy.
MR1703480,mass in right breast carcinoma breast.,right breast mass biopsy.,received 3 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section shows linear cores of fibrous tissue harboring an infiltrating lesion arranged in cords and sheets the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with areas of hemorrhage and necrosis. interspersed are lymphoplasmacytic infiltrate.,right breast mass biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1703486,mass in left breast carcinoma left breast,biopsy from left breast mass,received 4 grey white to grey brown linear cores measures 0.8 to 1.2cm. entire tissue processed.,sections show linear cores of breast parenchyma harboring an infiltrating lesion arranged in tubules and sheets. the cells are ovoid having moderate amount of cytoplasm. hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with chronic inflammatory infiltrate. areas of hemorrhage are seen.,biopsy from left breast mass:invasive ductal carcinoma grade ii )modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1703487,carcinoma left breast left axillary node metastatic.,biopsy from left axillary node.,received 5 grey white to grey brown linear cores measures 0.5 to 1.0cm. entire tissue processed.,linear core of lymphoid tissue infiltrated by neoplasm arranged as nests and islands. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. occasional mitosis seen.,biopsy from left axillary node:metastatic carcinoma of probable mammary origin.suggest confirmation.
MR1703496,right breast lump carcinoma right breast,biopsy from right breast lump,received multiple grey white linear cores measures 0.5 to 0.8cm. entire tissue processed.,sections show linear cores of fibrocollagenous tissue with few dilated ducts showing atypical cells having moderate amount of cytoplasm and hyperchromatic nucleus.,right breast biopsy:extensive fibrocollagenous stroma with tiny focus showing few atypical cells. inadequate for opinion. suggest repeat biopsy.
MR1703502,mass in right breast carcinoma breast,biopsy from right breast,received 5 grey white to grey brown linear cores measures 0.5 to 0.1cm. entire tissue processed.,sections show breast tissue with tumor arranged in cores and sheets .tumor cells showing pleomorphic hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. surrounding stroma shows elastosis and hyalinisation.,biopsy from right breast.infiltrating ductal carcinoma grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1703522,left breast mass.,left breast mass core biopsy.,received 3 grey white linear cores measures 1 to 1.4 cm. entire tissue processed.,sections shows cores of tissue infiltrated by tumor cells in tubules nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy :invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1703525,left breast lump carcinoma left breast,biopsy from left breast.,received 5 grey white linear cores measuring 0.6 to 0.8cm. entire tissue processed.,sections examined show linear cores of tissue with areas of necroinflammation foci of lymphoplasmacytic infiltrate.,biopsy from left breast:no viable tumor seen in the cores submittedonly necroinflammatory debris with lymphoplasmacytic and histiocytic infiltration kindly correlate with mammographic findings and suggest repeat if deemed necessary.
MR1703621,left breast mass carcinoma breast.,biopsy left breast.,received multiple grey white linear cores measures0.8 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating cellular lesion arranged in tubules cords and nests. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with chronic inflammatory infiltrate. areas of hemorrhage and necrosis are seen.,biopsy from left breast:invasive ductal carcinoma grade 1tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9
MR1703642,left breast mass,biopsy left breast.,received multiple grey white to grey brown linear cores measures0.5 to 1.0cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue harboring an infiltrating lesion arranged in sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. stroma shows desmoplasia with hyperchromatic infiltrates. areas of hemorrhage and necrosis are seen.,biopsy from left breast:invasive ductal carcinoma grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1703716,right breast lump c o carcinoma breast,right breast biopsy.,received multiple fragmented linear cores 0.4 to 0.8cm. entire tissue processed.,section shows breast parenchyma harboring an infiltrating lesion arranged in tubules and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with lymphoplasmacytic infiltrates. areas of hemorrhage and necrosis are seen.,right lump breast biopsy:invasive carcinoma nst grade. iitubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1703740,mass in left breast carcinoma breast.,biopsy from left breast.,received 3 grey white linear cores measuring 1 to 1.3cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged as nests tubules and cores. the cells have round to oval hyperchromatic nucleus moderate atyipa and scanty cytoplasm. intervening stroma shows hyalinisation and myxoid change.,biopsy from left breast:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9tubule formation 2nuclear pleomorphism 2mitoses 2
MR1703755,mass in left breast.,biopsy from left breast.,received 2 grey white linear cores measuring 0.8 to 1.2cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged in nests and tubules. the cells have round to oval hyperchromatic nucleus with moderate atypia and moderate amount eosinophilic to clear cytoplasm. intervening stroma shows inflammatory infiltrate and areas of fibrosis. ductal carcinoma in site with comedonecrosis noted.,biopsy from left breast:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9tubule formation 2nuclear pleomorphism 2mitotic 2dcis with comedonecrosis seen.
MR1703796,left breast retroareolar lesion carcinoma left breast.,biopsy from left breast retroareolar lesion.,received 3 grey white linear cores measures 1.0 to 1.5cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as tubules and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic to vesicular nuclear and moderate cytoplasm. the intervening stroma is elastotic.,invasive ductal carcinoma biopsy from left breast retroareolar lesion.modified bloom richardson score is 7 9 grade 2.tubular formation 3.nuclear pleomorphism 2.mitotic figures 2 7 9
MR1703808,left breast lump.,biopsy left breast.,received 3 grey white linear cores measuring 1 to 1.5cm. entire tissue processed.,received shows linear cores of tissue infiltrated by tumor cells arranged as diffuse sheets nests and tubules. the cells have round to oval hyperchromatic pleomorphic nucleus and moderate cytoplasm. stroma shows hyalinisation.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1703825,left breast lesion p o carcinoma breast.,biopsy from left breast.,received 3 grey white to grey brown linear cores measuring 0.7 to 1.5cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged as tubules and cords. the cells have round to oval hyperchromatic nucleus with moderate atypia and moderate cytoplasm. ductal carcinoma in site ( cribriform type) and comedonecrosis noted.,left breast lump core biopsy :invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1703832,left breast lump carcinoma left breast.,left breast lump core biopsy.,received 3 grey white linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows linear cores of tissue infiltrated by a lesion arranged in diffuse sheets. the cells have round to oval hyperchromatic moderately polymorphic nucleus and moderate cytoplasm. areas of necrosis noted.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1703833,right lower chest wall lesion known case of carcinoma breast post operation,biopsy from right lower chest wall lesion,received multiple grey white to grey brown linear cores measures 1 to 1.cm. entire tissue is processed,sections from the linear core submitted as right lower chest wall lesion shows infiltrating cords sheetsand aggregates of neoplastic cells with vesicular nucleus and small nucleoli. cytoplasm is scant tomoderate is scant in amount. at places the cells show clearing. amidst are mitotic figures and karyorrhectic debris,poorly differentiated malignancy possibly metastatic carcinoma in a known and treated case of carcinoma breastsuggest ihc
MR1703850,left breast lump carcinoma breast.,left breast lump core biopsy.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1703879,left breast lesion possibility of carcinoma breast.,left breast core biopsy.,received five grey white to grey brown linear cores measures 1 1.5 cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1703909,lump in right breast carcinoma right breast.,biopsy from right breast lesion.,received 3 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma exhibiting few ducts showing proliferation of round to oval cells with irregular slit like spaces. occasional cells show vesicular nuclei and rare mitotic figures is seen.,biopsy from right breast lesion:small focus of atypical ductal hyperplasiakindly correlate with mammographic findings and suggest repeat biopsy or excision if deemed necessary.
MR1703914,right breast lesion mufti focal carcinoma breast.,right breast core biopsy:,received 4 grey white linear cores measuring 0.6 to 1.2cm. entire tissue processed.,section show linear cores of tissue with a lesion arranged in glandular cribriform pattern and sheets. individual cells have polymorphic round to oval hyperchromatic nuclei inconspicuous nucleoli and moderate amount of cytoplasm stroma show desmoplasia. mitotic figures discerned.,right breast core biopsy:invasive carcinoma nucleus grade iitubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR1703926,left breast mass.,left breast mass core biopsy.,received 4 grey white linear core ranging measuring 0.5 to 1cm. entire tissue processed.,section show linear cores of breast parenchyma with a neoplastic lesion arranged is cords and sheets. individual cells have pleomorphic round to oval hyperchromatic nuclei and moderate to scant amount of cytoplasm . stroma show desmoplasia and hyalinisation adjacent breast show usual ductal hyperplasia.,left breast mass core biopsy:invasive carcinoma nst nuclear grade ii.peri neural invasion seen.
MR1703936,left breast mass carcinoma breast,biopsy from left breast mass,received multiple grey white linear cores measures 0.8 to 1.2cm.entire tissue is processed,multiple cores from breast shows tumor arranged in nests and cords. the cells have abundant cytoplasm with vesicular nuclei and prominent nucleoli. there is moderate amount of nuclear pleomorphism. mitotic figures are 5 10hpf. stroma is showing dense lymphoplasmacytic infiltrate.lymphovascular invasion noted,left breast invasive ductal carcinoma grade ii(6 9)mbr score 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9 lymphovascular invasion seen
MR1703953,carcinoma right breast,a) right breast lump wide local excisionb) sentinel lymph nodesc) right axillary lymph node dissection,a) right breast lump wide local excision:received lumpectomy specimen measures 5.5x4x2.5cm skin ellipse measures 4.5x1.3cm.cut surface shows illdefined grey white lesion measures 2x1x1cm.located at the following distancefrom the respective margins :superior margin 1cminferior margin 2cmmedial margin 0.6cmlateral margin 1.5cmdeep margin 0.8cmb) sentinel lymph nodes:received 2 fibrofatty tissue altogether measures 4x3x0.8cmlargest lymph nodes measures 2.5x0.6x0.4cm. cut surface shows grey whiteentire tissue is processedc) right axillary lymph node dissection:received fibrofatty tissue measures 8x6x3cm largest lymph node measures 2x1.2x1cm cut surfaceshows grey brown,sections reveal breast parenchyma harboring a neoplastic lesion arranged in tubular configuration consisting of low columnar to oval cells demonstrating moderate nuclear pleomorphism and eosinophiliccytoplasm amidst a desmoplastic stroma,a) right breast lump wide local excision:invasive ductal carcinoma grade itubule formation 2nuclear pleomorphism 2mitotic figures 1 5 9 tumor measures 2 cm in the greatest dimensionlymphovascular invasion presentperineural invasion not presentall resected margins are free of tumorsuperior margin free of tumorinferior margin free of tumormedial margin free of tumorlateral margin free of tumordeep margin free of tumorb) sentinel lymph nodes:2 sentinel lymph nodes (frozen section) show metastatic deposits.no perinodal spread seenc) right axillary lymph node dissection:22 lymph nodes isolated are free of tumor(0 22)
MR1703973,left breast lump.,left breast core biopsy.,received 4 grey white to grey brown linear core ranging from measuring 0.6 to 1 cm. entire tissue processed.,section show linear cores of tissue harboring a neoplastic lesion arranged in nest cords and sheets. individual cells have pleomorphic round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma show desmoplasia with lymphocytic and plasmacytic infiltrate. lymphovascular invasive is identified.,left breast core biopsyinvasive ductal carcinoma grade ii.modified bloom richardson score 6( 3+2+1)lymphovascular invasion is identified .
MR1703974,multicentric left breast lesion.,left breast lump core biopsy.,received 4 greywhite linear cores measuring 1 to 1.4cm. entire tissue processed.,section shows tumor cells in nests and diffuse sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified br score is 6 (3+2+1).
MR1703989,right breast lump carcinoma breast.,biopsy from right breast .,received 3 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged as nests and islands. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,biopsy from right breast:invasive ductal carcinoma.modified bloom richardson score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1704010,bilateral breast lumpleft breast lump with ulceration,biopsy from left breast lump,received 3 grey white to grey brown linear cores measuring 0.8 to 1cm. entire tissue processed.,section shows breast parenchyma harboring a lesion arranged in sheets and cords. cells are moderately pleomorphic with hyperchromatic nuclei and scant cytoplasm. stromal hyalinisation noted. dense inflammatory infiltrate seen. mitotic figures discerned.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1704053,left breast lesion carcinoma breast.,biopsy from left breast.,received 4 grey white to grey brown linear cores measures 0.8 to 1.2cm. entire tissue processed.,received 4 grey white linear core of breast parenchyma with a neoplastic lesion arranged in nests sheets. individual cells have pleomorphic round to oval hyperchromatic nuclei inconspicious nucleoli and moderate amount of pale eosinophilic granular cytoplasm. stroma show desmoplastic with lymphocytic aggregates crush artifacts and congested hyalinized blood vessels.,left breast core breast:invasive carcinoma grade ii.modified bloom richardson score is (3+2+1).
MR1704057,k c carcinoma right breast now with right lung mass.,biopsy from right lung lesion.,received 8 grey white to grey block linear cores measuring 0.6 to 1cm. entire tissue processed.,fragmented linear cores of tissue exhibiting sheets and nests of fesiform to round cells demonstrating dark staining nuclei and moderate amount of eosinophilic cytoplasm with brisk mitotic activity and prominent areas of necrosis.,biopsy from right lung lesion:the features are suggestive of metastatic carcinoma in a known case of carcinoma breast primary lung neuroendocrine neoplasm
MR1704081,birads v lesion in right breast.,biopsy from right breast.,received 4 grey white linear cores measuring 0.8 to 1.2cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring a neoplastic lesion arranged in trabeculae cords and sheets. the cells are round to oval with vesicular nuclei prominent nucleoli. mitoses seen. areas of fibrosis seen.,invasive carcinoma biopsy from right breast.modified br score is 7 9. grade 2.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1704124,right breast.,right breast biopsy.,received multiple grey white linear cores measuring 0.5 to 1cm. entire tissue processed.,section shows linear cores of breast linear cores of breast parenchyma harboring an infiltrating cellular lesion arranged in nests. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma shows desmoplasia with chronic inflammatory infiltrates. areas of hemorrhage and necrosis seen. ductal carcinoma in situ with comedonecrosis and calcification noted.,right breast biopsy:invasive carcinoma nst grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 ductal carcinoma in situ with comedonecrosis seenfoci of calcification seen.
MR1704145,birads v lesion in right breast.,right breast core biopsy.,received 3 grey white linear cores measuring 1 to 1.3cm. entire tissue processed.,section linear cores of tissue with a lesion arranged in nest cords and sheets. individual cells have pleomorphic round to oval hyperchroamtic nuclei and moderate amount of cytoplasm. few aporcine metaplastic cells seen. stroma show desmoplasia and inflammatory cells. mitotic figures discerned,right breast core biopsy:invasive carcinoma nst grade iimodified bloom richardson score 6 (3+2+1)
MR1704163,left breast lump carcinoma left breast.,left breast core biopsy.,received 4 grey white linear cores measuring 0.5 to 1.2cm. entire tissue processed.,section show linear cores of tissue with and lesion arranged is nest cores and sheets. individual cells have pleomorphic round to oval hyperchromatic nuclei inconspicuous nucleoli and moderate amount of cytoplasm. stroma show desmoplasia with lymphoplasmacytic infiltrate. mitotic figures discerned.,left breast core biopsy:invasive ductal carcinoma grade iimodified bloom richardson score 7(3+2+2)
MR1704209,right breast mass carcinoma breast.,biopsy from right breast.,received 3 grey white to grey brown linear cores measuring 0.5 to 1.2cm. enter tissue processed.,section shows linear cores of tissue harboring a lesion arranged as cords and tubules. the cells have round to oval hyperchromatic nuclei and with moderate atypia and scanty to moderate cytoplasm. stroma shows hyalinisation. lymphovascular invasion identified,biopsy from right breast:invasive duatal carcinoma grade imodified bloom richardson score is 5 9tubule formation 2nuclear pleomorphism 2mitosis figures 1
MR1704246,left breast mass carcinoma breast.,biopsy from left breast.,received 4 grey white linear cores measuring 0.3 to 1cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged as nests tubules and cores. the cells have round to oval hyperchromatic nucleus with mild to moderate atypia and moderate cytoplasm. stroma shows hyalinisation lymphocytic infiltrate and histiocytes,biopsy from left breast:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9tubule formation 2nuclear pleomorphism 2mitoses 2
MR1704293,suggestive of small 21x12cm. hypoechoic lesion with calcification left breast multicantive birads 5 lesion.,left breast core biopsy.,received multiple grey white linear cores measures 0.3 to 0.5cm. entire tissue processed.,section show linear cores of tissue with a lesion arranged in nest cord and sheets. individual cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows desmoplasia and focal areas of necrosis. mitotic figures discerned.,left breast core biopsy:invasive carcinoma nst grade ii.mbr score 6(3+2+1).
MR1704297,left breast lump carcinoma breast.,left breast core biopsy.,received 3 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section show linear cores of tissue show extensive desmoplasia with intermixed sheets of scattered cells having round to oval hyperchromatic nuclei and moderate amount of cytoplasm . mitotic figures discerned. areas of necrosis and karyorrhectic debris seen.,left breast core biopsy:invasive carcinoma nst grade ii.
MR1704298,carcinoma right breast,right breast right lumpectomy specimen,received lumpectomy specimen measures 8x5.5x2cm skin ellipse with nipple areola measures3.5 x 3.5. nipple areola complex unremarkable. cut section shows grey white lesion with cystic and solid lesion measuring 2.5 x 2 x 2 cm. located at the following distances from the respective margins:12 o clock 0.5cm3 o clock 2.0cm9 o clock 2.5cm6 o clock 2.5cmdeep margin 1.5cmrepresentative sections are submitted.,section studied show breast parenchyma harboring a lesion arranged in sheets cystic and papillarypattern. cells are closely packed with vesicular nuclei prominent nucleoli and moderate amountof cytoplasm. myoepithelial layer is not seen. stromal hyalinisation noted. mitotic figures discerned,right breast right lumpectomy :suggestive of invasive papillary carcinoma. tumour measures 2.5 cm in greatest dimension. lymphovascular invasion is not identified. perineural invasion is not identified. dcis component is not identified. all margins of resection are free of tumour.ihc done shows tumour cells to be positive for cytokeratin 7 and to be negative for calponin and p63 supporting the above impression.
MR1704328,birads v lesion in left breast.,biopsy from left breast lump.,received 5 grey white linear cores measuring 1.2 to 1.5cm. entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as islands and sheets. the neoplastic cells exhibit moderate nuclear pleomorpism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. areas of necrosis seen.,biopsy from left breast:invasive ductal carcinoma.modified bloom richardson score grade 3tubule formation 3nuclear pleomorpism 2mitotic 3
MR1704335,right breast lump.,right breast lump core biopsy.,received multiple grey white linear cores measures 0.3 to 0.5cm. entire tissue processed.,section shows tumor cells in nests and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1704358,left breast birads,biopsy from left breast lump.,received 4 grey white linear cores measuring 0.8 to 1.3cm. entire tissue processed.,section shows tumor cells in cords nests and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1)
MR1704368,lump left breast carcinoma breast.,left breast core biopsy.,received 3 grey white linear cores measuring 1 to 1.4cm. entire tissue processed.,section shows tumor cells in tubules nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy :invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1704369,lump in right breast fungating and surrounded by skin nodules. carcinoma right breast.,skin nodules incision biopsy.,received 2 bits one skin covered soft tissue bits measures 1x1x0.8cm skin measures 1x1cm other soft tissue bits measures 0.8x0.8x0.2cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,skin nodules incision biopsy( lump in right breast fungating):positive for malignancy.suggestive of metastatic tumor deposits in a known case of carcinoma breast. tumor is reaching upto the overlying skin (dermis) no ulceration is seen.
MR1704376,mass in right breast carcinoma breast.,biopsy from right breast mass.,received 3 grey white linear cores measuring 1 to 2cm. entire tissue processed.,section show linear cores of breast parenchyma with a neoplastic lesion arranged in nest cords and sheets. individual cells have pleomorphic round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma show desmoplasia with scattered inflammatory cells and hyalinised blood vessels. mitotic figures and area of calcification seen.,right breast core biopsy:invasive carcinoma grade iimodified bloom richardson score (3+2+1)
MR1704378,right breast lump p o carcinoma breast.,biopsy from right breast lesion.,received 3 grey white linear cores measuring 0.7 to 1.2cm. entire tissue processed.,linear cores of tissue exhibiting sheets of round to oval neoplastic cells harboring vesicular nuclei demonstrating moderate nuclear pleomorphic and eosinophilic cytoplasm amidst desmoplastic stroma. there are foci of necrosis.,biopsy from right breast lesion:invasive carcinoma grade iiimodified bloom richardson score :8 9tubule formation 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR1704379,ill defined hypochoci heterogeneous mass with calcification foci at peciareolar lesion at 2 0 clock left breast.,biopsy from left breast.,received 4 grey white linear cores measures 0.8 to1.2 cm. entire tissue processed.,section shows cores of fibrofatty tissue with neoplastic cells arranged in strands and cords cells exhibits moderate nuclear pleomorphism with hyperchromatic nuclei and moderate eosinophilic cytoplasm. stroma shows sparse lymphocytic infiltration and marked desmoplasia.,biopsy from left breast:invasive carcinoma nuclear grade ii. with lobular differentiation.
MR1704395,right breast lump carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows cores of breast parenchyma harboring a lesion arranged in cores and lobules cells exhibit moderate nuclear pleomorphism with hyperchromatic nuclei and moderate eosinophilic cytoplasm. mitotic figures discerned. peritumoral lymphocytic infiltration and tiny focus of dcis with comedonecrosis seen.,biopsy from right breast:invasive ductal carcinoma grade ii.mbr score 6 9.tubular formation 2.nuclear pleomorphism 2.mitotic figures 2.tiny focus of dcis with comedonecrosis seen.
MR1704403,left breast mass carcinoma breast.,biopsy from left breast mass.,received 4 grey white linear cores measuring 0.5 to 1cm. entire tissue processed.,section show linear cores of tissue harboring a lesion arranged in nest and sheets. individual cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma show desmoplastic and congested blood vessel.,left beast core biopsy:invasive ductal carcinoma grade iimodified bloom richardson score 6( 3+2+1)
MR1704420,right breast lump carcinoma breast.,biopsy from right breast lesion.,received multiple grey white linear cores measures 1 to 1.4 cm. entire tissue processed.,linear cores of tissue show solid aggregates and sheets of neoplastic cells. the cells are round to oval demonstrating moderate nuclear pleomorphism eosinophilic cytoplasm and brisk mitotic activity amidst prominent mixed inflammatory infiltrate. few cells show prominent nucleoli,biopsy from right breast lesion:poorly differentiated malignancy.suggest ihc.
MR1704463,left breast lump p o carcinoma breast.,biopsy from left breast.,received five grey white linear cores measures 0.8 to 1.2cm. entire tissue processed.,section shows cores of breast parenchyma infiltrated by a lesion arranged in tubules cords and nests. cells are larged with round to oval pleomorphic hyperchromatic nuclei prominent nucleoli and moderate amount of granular eosinophilic to clear cytoplasm. also seen ductal carcinoma in situ cribriform and comedonecrosis type. stroma shows extensive hyalinisation with few areas showing apocrine metaplasia. areas of necrosis seen.,biopsy from left breast:invasive ductal carcinoma grade 2 with ductal carcinoma in situ ( comedonecrosis and cribriform type).modified bloom richardson scoretubule formation: 3nuclear pleomorphism: 2mitotic figures: 2 7 9.
MR1704472,left breast lump carcinoma breast.,left breast lump core biopsy.,received multiple grey white to grey brown linear cores measures 0.3 to 1cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1704479,left breast lump carcinoma breast.,left breast core biopsy.,received four grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in nests cords and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. occasional foci of calcification are seen.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score 6(3+2+1).
MR1704500,left breast mass birad iv c,left breast core biopsy.,received multiple grey white to grey brown linear cores measuring 0.6 to 1cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged in papillary and sheets. individual cells show mild to moderately pleomorphic hyperchromatic nuclei and moderate amount of eosinophilic to granular cytoplasm. stroma adeno and fibrosis noted. congested blood vessels and areas of hemorrhage noted.,left breast core biopsy:invasive carcinoma nuclear grade ii with papillary features.
MR1704540,left breast,biopsy from left breast.,received multiple grey white linear cores measuring 0.5 to 0.8cm. entire tissue processed.,section shows linear cores of necrosis inflammatory tissue algorithm few islands showing diffuse sheets of atypical round to ovoid cells hyperchromatic moderately pleomorphic nucleus and scanty cytoplasm. mitotic figures discerned.,biopsy from left breast invasive carcinoma no specific type grade 2modified bloom richardson score is 7 9tubule formation 3nuclear pleomorphism 2mitosis 2large areas of necrosis seen.
MR1704548,left breast lump.,biopsy from left breast lump.,received multiple fragmented grey white linear cores measuring 0.3 to 0.8cm. entire tissue processed.,section shows breast parenchyma harboring a lesion arranged in nests and cores. the neoplastic cells are moderately pleomorphic with hyperchromatic nuclei and moderate amount of cytoplasm. stromal hyalinisation noted.,left breast lump biopsy:invasive ductal carcinoma grade 2 (6 9)tubule formation 3nuclear pleomorphism 2mitotic figures 1
MR1704601,right breast lump p o carcinoma breast.,biopsy from right breast lump.,received multiple fragmented grey white linear cores measures 0.3 to 0.5cm. entire tissue processed.,section shows cores of breast parenchyma showing normal ductules lined by inner epithelial and outer myoepithelial layer. few dilated and hyperplastic ducts are noted. stroma shows fibrosis and hyalinized blood vessels. one focus shows degenerated cells debris admixed with hemorrhage. also seen 2 ducts showing apocrine metaplasia.,biopsy from right breast lump:no evidence of malignancy in the smears studied.suggest repeat biopsy if clinically warranted.
MR1704602,carcinoma breast post op.,endometrial biopsy.,received multiple grey white soft tissue bits altogether measures 1.5x0.5x0.5cm. entire tissue processed.,sections shows occasional endometrial glands lined by tall columnar epithelium. stroma shows plump cells spindle cells congested capillaries and areas of hemorrhage. no atypia is seen.,endometrial biopsy:shows benign endometrial tissue.negative for malignancy.
MR1704611,mass in left breast carcinoma breast.,left breast mass biopsy.,received 4 grey white linear cores measuring 0.5 to 1cm. entire tissue processed.,section shows cores of breast parenchyma harboring a lesion arranged in nests cores and trabeculae comprising of medium sized cells with round to oval pleomorphic hyperchromatic nuclei few showing intracellular inclusions and moderate amount of eosinophilic cytoplasm. foci of necrosis noted. stroma shows desmoplasia and lymphoplasmacytic infiltrate. areas of hemorrhage seen.,left breast mass biopsy:invasive ductal carcinoma grade 2modified bloom richardson score (3+2+1) 6 9
MR1704672,right breast retro areolar mass.,biopsy from right breast.,received 4 grey white to grey brown linear core measures 0.5 to 0.8cm. entire tissue processed.,section shows invasive sheets and nests of atypical ductal cells showing mild anisonucleosis and hyperchromatic nuclei. there cells are seen invading the dense desmoplastic stroma. sparse lymphocytic infiltrates are seen.,biopsy from right breast:invasive carcinoma nst grade i.mbr score (2+1+1).
MR1704682,mass in left breast carcinoma breast,biopsy from left breast mass,received 2 grey white linear cores measures 1 to 1.2cm. entire tissue is processed,section shows cores of breast parenchyma infiltrated by a lesion arranged in nests cords and trabeculae. cells are large with round to oval pleomorphic hyperchromatic nuclei few showing prominentnucleoli and moderate amount of eosinophilic cytoplasm. few bizzare looking cells and multinucleate giantcells seen. brisk mitoses along with atypical mitotic figures noted. stroma shows fibrosis lymphoplasmacyticinfiltrates and areas of fibrosis.,left breast mass biopsy:invasive ductal carcinoma grade 3mbr score 3+3+2 8 9tubule formation 3nuclear pleomorphsim 3mitotic figures 2 8 9
MR1704737,right breast mass.,biopsy from right breast.,received four grey white linear cores measures 0.5 to 1cm. entire tissue processed.,multiple linear cores from breast shows tumor arranged in sheets cords nest and as individual scattered cells. the cells are plasmacytoid with eccentric nuclei showing moderate amount of pleomorphism and hyperchromatic nuclei and cytoplasm showing vacuolation. m.f 1 2 10hpf.,biopsy from right breast:suggestive of invasive carcinoma with lobular differentiation and signet ring pattern nuclear grade ii.
MR1704751,left breast mass.,biopsy from left breast.,received 4 grey white linear cores measuring 0.8 to 1.2cm. entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as clusters and tubules and nests. the neoplastic cells exhibit moderate nuclear pleomorphic have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. lymp vesicular invasive seen. the intervening stroma is scant.,biopsy from left breast:invasive ducatal carcinoma.modified bloom richardson grade 2 (7 9)tubule formation 3nuclear pleomorphism 2mitotic figures 2
MR1704752,left breast mass carcinoma breast.,biopsy from left breast mass.,received 3 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a lesion arranged in cords and nests. cells are pleomorphic with round to oval hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. stroma shows extensive desmoplasia and lymphocytic infiltrates. also seen ductal carcinoma in situ papillary and solid type loss of crush artifact seen.,biopsy from left breast mass:dcis with few foci showing invasive carcinoma.in view of lots of crush artifact and desmoplasia suggest repeat biopsy for further testing.
MR1704754,left breast lump carcinoma breast.,biopsy from left breast.,received three grey white linear cores measures 0.8 to 1.0cm. entire tissue processed.,linear cores from shows tumor arranged in cords trabecule and nests. the cells are having moderate to abundant cytoplasm with hyperchomatic nuclei. there is moderate to marked nuclear pleomorphism. areas of dcis present. mitotic figures 3 10 hpf. intervening stroma showing lymphocytic infiltrate.,biopsy from left breast:invasive ductal carcinoma grade ii (6 9).mbr score 2+2+2 6 9.focus of dcis seen
MR1704758,right breast mass carcinoma breast.,biopsy from right breast.,received multiple fragmented grey white linear cores measuring 0.3 to 0.8cm. entire tissue processed.,section shows linear cores of tissue harboring extensive areas of ductal carcinoma in situ. cribriform pattern and ductal carcinoma in situ with comedonecrosis noted.,biopsy from right breast:extensive ductal carcinoma in situ nuclear grade 2
MR1704784,known case of carcinoma left breast status post mrm.,parasternal lesion core biopsy.,received four greywhite to greybrown linear cores measuring 0.4 to 0.6cm. entire tissue processed.,linear cores of tissue show collagenous tissue with infiltrating sheets and nest of dysplastic oval cells with hyperchromatic nuclei and abundant eosinophilic cytoplasm moderate to marked nuclear pleomorphism. few cells show prominent nucleoli. occasional mitotic figure is seen. the stroma shows lymphomononuclear infiltrate.,parasternal lesion core biopsy:morphology favours recurrent ductal carcinoma in a known case of carcinoma breast.
MR1704827,right breast lump p o carcinoma breast.,biopsy from right breast.,received 5 grey white linear cores measures 0.8 to 1.4cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a lesion arranged in vague tubules cords and nests. cells are large with round to oval hyperchromatic pleomorphic nuclei conspicuous nucleoli and moderate amount of eosinophilic cytoplasm. stroma shows desmoplasia and hyalanised blood vessels.,biopsy from right breast:invasive ductal carcinoma grade 2.modified bloom richardson scoretubule formation: 3nuclear pleomorphism:2mitotic figures: 2 7 9.
MR1704833,lump right breast.,right breast biopsy.,received 4 grey white linear cores measuring 0.5 to 1cm. entire tissue processed.,section shows cores of breast parenchyma showing ductal carcinoma in situ comedonecrosis pattern. one foci shows suspicious breach in the myoepithelial layer. adjacent stroma shows fibrosis lymphocytic aggregates necrosis and hemorrhage .,right breast biopsy:extensive ductal carcinoma in situ with a focus suspicious of micro invasion.suggest ihc.
MR1704886,right breast lump p o carcinoma breast.,right breast biopsy.,received 3 grey white to grey brown linear corers measuring 0.8x1cm. entire tissue processed.,section shows multiple fragments harboring a neoplastic lesion arranged in fascicles and in sheets. the cells are spindle shaped with wavy nuclei and eosinophilic cytoplasm. there are focal area showing chondromyxoid background with cells having vacuolated cytoplasm and hyperchromatic nuclei . areas of hyalinisation and fibrosis seen.,right breast biopsy :suggestive of spindle cell neoplasm. phyllodes tumor. sarcoma.suggest excision of the lump for further confirmation.
MR1704914,right breast lump.,right breast lump biopsy.,received 3 grey white linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma with extensive areas of desmoplasia. occasional foci of an infiltrating lesion arranged in tubules nests and singly scattered atypical ovoid cells having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli are seen. stroma shows scattered lymphoplasmacytic infiltrates are seen. adjacent breast shows fibro adenosis.,right breast lump biopsy:small focus suggestive of invasive carcinoma nst grade ii.see commentmodified bloom richardson score is 6 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 comment:tissue might get exhausted for the receptor studies as the representative tissue is scant.
MR1704919,left breast mass carcinoma breast.,biopsy from left breast mass.,received 4 grey white linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows breast parenchyma harboring a lesion arranged in nests tubules and cords. cells have hyperchromatic nuclei and moderate amount of cytoplasm. stromal desmoplasia noted.,left breast mass biopsy:invasive ductal carcinoma.modified bloom richardson score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1704940,known case of carcinoma breast left pleural nodule metastatic.,biopsy from pleural nodule.,received 6 greywhite to greybrown linear cores measuring 1 to 1.2cm.,linear cores of tissue show invasive sheets and vague acinar aggregates of dysplastic oval cells with hyperchromatic nuclei moderate nuclear pleomorphism and abundant eosinophilic cytoplasm. intervening stroma is desmoplastic.,invasive carcinoma favor metastatic deposits in a known case of carcinoma breast.please await report on ihc.
MR1704987,right breast mass carcinoma breast.,received breast biopsy.,received 3 grey white linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in targetoid manner cores and nests. the cell are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. intervening stroma is desmoplasic lymphoplasmactic and vistiocytic infiltrates. areas of hemorrhage are seen. adjacent breast shows fibroadenosis .,right breast biopsy:invasive carcinoma nst grade 2 modified bloom richardson score is 6 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9.
MR1705022,right breast mass carcinoma breast.,biopsy from right breast mass.,received grey white to grey brown linear cores measuring 0.7 to 1.2cm. entire tissue processed.,linear cores of breast pareachyma infiltrated by a neoplasm arranged as glands and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic to vesicular nuclei with conspicuous nucleoli and moderate cytoplasm .foci of necrosis with comedo pattern seen. the intervening stroma is desmoplastic.,biopsy from right breast:modified bloom richardson score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1705044,left breast mass carcinoma left breast.,biopsy from left breast mass.,received 5 grey white to grey brown linear cores measuring 1.2 to 1.3cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in tubules and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma shows desmoplasia with lyphoplasmacytic infiltrates.,left breast mass biopsy:invasive carcinoma nst grade 1tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9
MR1705052,right breast mass carcinoma right breast.,biopsy from right breast mass.,received 3 grey white to grey brown linear cores measuring to cm. entire tissue processed.,section shows cores of breast parenchyma harboring a lesion arraigned in islands and nests cells are large with hyperchromatic irregular nucleus exhibiting moderate pleomorphism and moderate amount of eosinophilic cytoplasm. few cells have prominent eosinophilic nucleoli. stroma shows fibrosis and lymphoplasmacytic infltrates. areas of necorsis noted. few hyalinesid blood vessels seen.,right breast mass biopsy:invasive ductal carcinoma grade 2modified bloom richardson score 3+2+1 6 9dcis with comedonecrosis seen.
MR1705060,right breast lump birads v lesion.,biopsy from right breast lump.,received 4 grey white to grey brown linear cores measuring 1 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as islands and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is elastotic. areas of necrosis seen.,biopsy from right breast:infiltrating ductal carcinoma modified bloom richardson score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1705076,right breast lesion.,"biopsy from breast a) 3""0 clock and b) retro areolar 12 0 clock lesion.",received 3 grey white to grey brown lower cores measuring 0.7 to 1cm. entire tissue processed.,sections from both sites show similar morphologysection shows linear cores of breast parenchyma infiltrated by a lesion arranged in nests tubules cords and trabecular cells have round to oval vesicular nucleoli prominent nucleoli and scanty to moderate eosinophilic cytoplasm. stroma shows chondroid element and myxoid change. focal areas of necrosis noted. small branching vascular proliferation noted. extensive areas of squamous metaplasia is noted with floating tumor cells.,a b)biopsy from breast 3 0 clock and 12 0 clock lesion :metaplastic carcinoma with cartilagenous and squamous differentiated.
MR1705086,right breast lump p o carcinoma breast.,biopsy from right breast lump.,received 3 grey white linear cores measuring 0.8 to 1.1cm. entire tissue processed.,section show cores of breast parenchyma showing in infiltrate lesion arranged in nests and cords cells are large with pleomorphic round to oval vesicular nuclei prominent nucleoli and moderate amount of eosinophilic cytoplasm. ex ductal carcinoma in situ noted with comedo necrosis pattern. stoma shows fibrosis and abundant lymphoplemocytic infiltrates.,right breast lump biopsy:invasive ductal carcinoma grade 2modified bloom richardson score : 3+2+2 7 9with ductal carcinoma in situ(comedonecrosis type)
MR1705108,right breast lump.,right breast mass biopsy.,received multiple grey white to grey brown linear cores measuring 0.4 to 0.7cm. entire tissue processed.,section cores of breast parenchyma harboring an infiltrating cellular lesion arranged in sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. stroma shows desmoplasia with lymphocytes and plasmacells and necrosis are seen.,right breast mass biopsy :invasive carcinoma nst grade 2.modified br score is 7 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1705117,right breast mass birads v lesion,biopsy from right breast mass,received multiple grey white to grey brown linear cores measures 1 to 1.2cmentire tissue is processed,section shows linear cores of breast parenchyma infiltrated by a lesion arranged in nests cordsof trabeculae. cells have round to oval pleomorphic hyperchromatic nuclei with moderate amountof eosinophilic to pale granular cytoplasm. stroma shows extensive hyalinisation and fibrosis.mitoticfigures are discerned. focal areas show myxoid change and areas of hemorrhage,right breast mass biopsy:invasive ductal carcinoma grade 2mbr score tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR1705119,right breast lump,right breast lump core biopsy.,received multiple grey white to grey brown linear cores of measures 0.3 to 0.5cm. entire tissue processed.,section shows tumor cells in diffuse sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1705132,right breast mass carcinoma breast,biopsy from right breast mass,received multiple grey white to grey brown linear cores measures 1.2 to 1.3cm.entiretissue is processed,section shows linear cores of breast parenchyma infiltrated by a lesion arranged in cords and nests. cells have moderate amount of eosinophilic cytoplasm and pleomorphic hyperchromatic nuclei. stroma shows extensivedesmoplasia and lymphocytic infiltrate. no areas of necrosis seen,right breast mass biopsy:invasive ductal carcinoma grade 2mbr score 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1705153,right breast mass carcinoma right breast,biopsy from right breast mass,received multiple grey white to grey brown linear cores measures 1 to 1.2cm.entiretissue is processed,section shows linear cores of breast parenchyma harboring a lesion arranged in nests and cords. cells have abundant eosinophilic cytoplasm and large pleomorphic round to oval hyperchromatic nuclei ffew having prominent nucleoli.stroma shows hyalinisation. focal areas of necrosis seen,right breast mass biopsy:infiltrating ductal carcinoma grade 2mbr scores tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9 focal areas of necrosis seen
MR1705188,left breast mass carcinoma breast.,biopsy from left breast mass.,received 5 greywhite to greybrown linear cores measuring 0.8 to 1.3cm. entire tissue processed.,sections from the lnear core submitted from left breast shows an infiltrating lesion. the neoplastic cells are arranged as tubules cords and sheets of cell against the desmoplastic stroma. the neoplastic cells show moderate pleomorphism. cytoplasm is moderate in amount. mitotic figures discerned. foci of dcis noted.,invasive ductal carcinoma nst with dcis ( mbr score 6 grade ii).tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1705190,right breast solid cystic mass.,right breast core biopsy.,received five grey white linear cores measuring 0.4 to 1.2cm. entire tissue processed.,section show linear cores of breast parenchyma with a lesion arranged in papillary pattern nest and sheets. the neoplastic cells have round to oval hyperchromatic nuclei and moderate amount of pale eosinophilic cytoplasm. stroma shows bland spindle cells and desmoplasia .areas of necrosis seen.,right breast core biopsy :invasive carcinoma.modified br score is 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1705203,right breast mass carcinoma right breast.,biopsy from right breast.,received 4 grey white to grey yellow linear core measuring 1 to 1.2cm. entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as islands and nests and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is elastotic.,invasive ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2.tubuleformation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1705233,right breast lump carcinoma right breast.,biopsy from right breast.,received 4 grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue processed.,section shows cores of breast parenchyma infiltrating by cords and islands of atypical ce4lls having round to oval pleomorphic hyperchromatic nuclei inconspicious nucleoli and scanty cytoplasm. extensive areas of hyalinisation seen. stroma shows scattered fibroblasts and lymphocytes. focal areas of necrosis noted.,biopsy from right breast:infiltrating ductal carcinoma grade 2modified bloom richardson score is (3+2+1)6 9.areas of necrosis seen.
MR1705240,right breast mass,biopsy from right breast mass,received multiple grey white to grey yellow linear cores measures 1 to 1.4cm.entire tissue is processed,section shows linear cores of breast parenchyma harboring a lesion arranged in islands and cords. cells have ovoid vesicular pleomorphic nuclei prominent nucleoli and moderate amount of eosinophiliccytoplasm. stroma shows extensive hyalinisation and focal myxoid change. hyalinised blood vessels noted.no areas of necrosis seen,right breast mass biopsy:infiltrating ductal carcinoma grade 2mbr score 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1705241,right breast large lobulated.,right breast mass biopsy.,received 4 grey white to grey brown linear core measuring 0.8 to 1cm. entire tissue processed.,section shows linear cores of tissue harboring an infiltrating cellular lesion arranged in sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with chronic inflammatory infiltrates. areas of hemorrhage and necrosis are seen.,right breast mass biopsy :invasive carcinoma nst grade 2.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1705261,known case of carcinoma left breast post mastetomy bcsleft breast lump with ulceration.,biopsy from a b breast lump.,received right side 3 grey white to grey brown linear cores measures 0.4 to 0.6cm. entire tissue processed.,a b ) section shows linear cores of breast parenchyma cords by a lesion arranged in nests tubules cords and trabecular cords have normal to oval pleomorphic hyperchromatic nuclei with irregular nuclear contours few with prominent nucleoli and moderate to scanty eosinophilic cytoplasm. few cells show clearing of cytoplasm. stroma sows extensive desmoplasia and hyalinised blood vessels.*(section from both breasts show similar morphology),biopsy from a b breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9(3+2+1).
MR1705272,right breast mass carcinoma breast.,biopsy from right breast.,received 4 grey white to grey brown linear cores measures 1.2 to 1.4cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by cords and islands of atypical cells having round to oval hyperchromatic nuclei few with prominent nucleoli and moderate amount of eosinophilic cytoplasm. stroma shows extensive fibrosis focal areas of necrosis and few dilated blood vessels.,biopsy from right breast mass:invasive carcinoma nos grade 2modified bloom richardson score is (3+2+2 7 9.focal areas of necrosis seen
MR1705335,right breast mass carcinoma breast.,right breast lump core biopsy.,received 4 grey white to grey brown linear cores measures 0.7 to 0.9cm. entire tissue processed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1705365,right breast mass mammogram birads iv.,right breast mass biopsy.,received 4 grey white to grey brown linear cores measuring 0.7 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a lesion arranged in islands cords and file pattern comprising of atypical cells with hyperchromatic irregular nuclei prominent nucleoli and moderate amount of eosinophilic cytoplasm. few cells show cytoplasmic cleaving. background show extensive hyalinisation scattered lymphocytes and plasma cells.,right breast mass biopsy :invasive lobular carcinoma.nuclear grade 2.
MR1705374,left breast mass carcinoma left breast.,left breast mass biopsy.,received 5 grey white to grey brown linear cores measuring 0.4 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a lesion arranged in nests cords and vague tubules. cells are large with pleomorphic hyperchromatic nuclei few with prominent nucleoli and moderate eosinophilic cytoplasm. ductal carcinoma in situ is identified with comedonecrosis. stroma shows desmoplasia and lymphoplasmacytic infiltrates.,left breast mass biopsy :invasive ductal carcinoma grade 2.modified br score is 7 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 ductal carcinoma in situ identified with comedonecrosis.
MR1705400,known case of carcinoma breast with abdominal metastatic lymphoma granulomatous.,retroperitoneal node biopsy.,received four grey white to grey brown linear cores measuring 0.6 to 1cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue harbouring epitheloid cell clusters lymphocytes transforming histiocytes and laghans giant cells. stromal hyalinization noted.,retroperitoneal node biopsy :chronic granulomatous inflammation. probability of koch s etiology is considered.
MR1705409,right breast lump p o carcinoma breast.,right breast lump biopsy.,received 4 greywhite to greybrown linear core measuring 0.3 to 1cm.,section shows linear cores of breast parenchyma dilated and bronchial ductules arranged in papillary pattern. cells lining the ductules have hyperchromatic bland appearing nuclei with nuclear stratification and crowding few clusters show outer myoepithelial layer . adjacent stroma shows lymphocytic infiltrates.,right breast lump biopsy:papillary neoplasm.suggest larger biopsy to look for invasion.please correlate clinically
MR1705435,left breast lump.,biopsy from left breast lump.,received four greywhite to greybrown linear cores measuring 1.2 to 1.4cm. entire tissue processed.,section from the left breast lump shows cells arranged in clusters showing round hyperchromatic nucleus prominent nucleoli at placed and eosinophilic cytoplasm. necrosis noted.,biopsy from left breast lump:invasive carcinoma.modified br score : 8 9 grade iii.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR1705444,right breast mass.fnac lobular carcinoma.,biopsy from right breast lump.,received 3 grey white grey brown linear core measures 1.2 to 1.4cm.,section shows linear cores of breast parenchyma arranged in lobular nests islands and cords. tumor cells are small with round to oval nuclei exhibiting hyperchromasia and mild pleomorphism and incorpicious nucleoli. predominantly signet ring cells are seen with hyperchromatic dark eccentric nuclei and vacuolated cytoplasm. dense fibrotic stroma is noted with periductal elastosis. extracellular mucin is noted.,biopsy from right breast lump:invasive carcinoma nst nuclear grade 2 with few foci showing mucinous differentiation.
MR1705473,right breast lump carcinoma.,right breast lump biopsy.,received five grey white linear cores measuring 0.8 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in sheets and tubules. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. stroma shows desmoplasia with lymphocytic infiltrates. areas of hemorrhage and necrosis are seen.,right breast lump biopsy :invasive carcinoma nst grade 2.modified br score is 6 9.tubular formation : 2nuclear pleomorphism : 2mitotic activity : 2 6 9 ductal carcinoma in situ cribriform solid and comedonecrosis seen.
MR1705484,right breast mass carcinoma right breast.,biopsy from right breast mass.,received 5 greywhite to greybrown linear cores measuring 0.8 to 1.2cm. entire tissue processed.,needle core biopsy from right breast mass shows clusters of cells in mucinous background. one of the core shows cells in clusters and cords showing invasion into stroma. the cells show round nucleus and eosinophilic cytoplasm.,invasive carcinoma.mbr score 6 9 grade ii.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 extracellular mucin pools noted.
MR1705556,left breast mass.carcinoma breast.,left breast biopsy.,received multiple grey white linear cores measuring 0.6 to 1.0cm. entire tissue processed.,section shows linear ores of breast parenchyma harboring an infiltrating cellular lesion arranged in tubules and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. stroma is desmoplastic with chronic inflammatory infiltrates. areas of hemorrhage and necrosis seen.,left breast biopsy :invasive carcinoma nst grade 3.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR1705560,carcinoma left breast,a) left breast lump wide excisionb) sentinel lymph node biopsy,a) received lumpectomy specimen measures 8x5x2cm cut surface shows grey white area measures 2.5x1.2x1.0cm lateral and medial margin shows fibrotic arealocated at the following distances from the respective margins superior margin 0.4cminferior margin 1.0cmmedial margin 2.0cmlateral margin 0.3cmretroareolar margin 0.4cmdeep margin 1.0cmb) received multiple fibrofatty tissue altogether measures 4.5x2x1.2cm largest lymph node measures 2x1x1cm cut surface shows fatty infiltration,section show sheets of neoplastic cells having markedly pleomorphic round to oval vesicular nuclei prominent nucleoli and moderate amount of cytoplasm. many multinucleated pleomorphictumor giant cells seen. pink eosinophilic material osteoid seen with intermixed tumor cells. calcification noted ductal carcinoma in situ seen of solid cribriform and comedonecrosis type seen,left lumpectomyundifferentiated carcinoma metaplastic carcinoma with extensive ductal carcinoma in situ. suggest further confirmation by ihctumor measures 3.0cm in greatest dimensioninvasive component measures 1.2cm ductal carcinoma in situ measures 1.8cmlymphovascular invasion and perineural invasion not identifiedductal carcinoma in situ component solid cribriform and comedonecrosis of high grade seenall margins of resection are free of tumorsuperior margin free of tumorinferior margin free of tumormedial margin free of tumorlateral margin free of tumorb) sentinel lymph node biopsy:5 lymph nodes identified no deposits seen(0 5)summary:left lumpectomy:undifferentiated carcinoma metaplastic carcinoma with ductal carcinoma in situfive nodes no deposits of tumor (0 5)
MR1705590,lump left breast birads iii c lesion.,left breast core biopsy.,received 7 grey white to grey brown linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1705591,left breast lump carcinoma.,left breast lump biopsy.,received multiple grey white to grey brown linear cores measuring 0.5 to 0.8cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in sheets and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. stroma shows desmoplasia with lymphocytic infiltrates. areas of hemorrhage and necrosis are seen. foci of calcification seen.,left breast lump biopsy :invasive carcinoma nst grade 2.modified br score is 6 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1705607,left breast lump carcinoma.,left breast lump biopsy.,received multiple fragmented grey white to grey brown linear cores measuring 0.3 to 0.8cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue with extensive areas of necrosis. an infiltrating lesion with ductal pattern and in nests seen. cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. stroma shows desmoplasia. areas of ductal carcinoma in situ seen.,left breast lump biopsy :suggestive of invasive carcinoma with ductal carcinoma in situ and comedonecrosis.
MR1705609,left breast irregular likely malignant.,left breast lump biopsy.,received multiple grey white to grey brown linear cores measuring 0.5 to 1.0cm. entire tissue processed.,section shows linear ores of breast parenchyma harboring an infiltrating lesion arranged in tubules and sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with chronic inflammatory infiltrates.,left breast lump biopsy :invasive carcinoma nst grade 2.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 3 7 9
MR1705610,carcinoma left breast.,left breast mass biopsy.,received five grey white to grey brown linear cores measuring 0.8 to 1.2cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue harboring an infiltrating lesion arranged in cords tubules and sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. stroma shows desmoplasia with lymphocytic infiltrates. areas of hemorrhage and necrosis are seen.,left breast mass biopsy :invasive carcinoma nst grade 2.modified br score is 7 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1705612,paget s nipple entire nipple involved right breast,excision biopsy of right nipple,received skin covered fibrofatty tissue measures 2x2x2cm excoriation seen in the nipple regioncut surface shows grey white area measures 1.8x1.8x1.8cm.located at the following distances from the respective margins:superior margin 0.2cminferior margin 0.2cmmedial margin 0.2cmlateral margin 0.2cmdeep margin 0.2cm,multiple sections demonstrates stratified squamous epithelium with underlying proliferation of ductulesand tubules consisting of cuboidal to oval cells harboring vesicular nuclei and moderate amount of eosinophilic cytoplasm.many ductules are bilayered. lymphovascular invasion is not identified. perineuralinvasion is noted. intervening areas show fibrocollagenous stroma. infiltrating into the overlying epidermis is also evident.,excision biopsy of right nipple: infiltrating syringomatous adenoma invasive ductal carcinomasuggest ihclesion measures 1.8cm in the greatest dimensionlymphovascular invasion not identifiedperineural invasion identifiedmargins:superior margin free of tumormedial margin involvedlateral margin free of tumordeep margin free of tumorreport on inferior margin to follow
MR1705620,right breast mass.carcinoma breast.,right breast mass biopsy.,received multiple grey white linear cores measuring 0.5 to 1.0cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in nests and tubules. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma shows desmoplasia with chronic inflammatory infiltrates.,right breast mass biopsy :invasive carcinoma nst grade 2.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1705640,known case of carcinoma right breast post lumpectomy post chemotherapy.,a) wide local excision of previous lumpectomy site.b) right axillary lymph node.c) level 3 lymph node.,a) received wide local excision specimen with skin measures 9.5x5x3.5cm. skin ellipse measures 7x0.9cm. cut surface shows fibrotic area measures 4x3x2cm. no gross tumor is seen.distance from margins:superior margin : 1cminferior margin : 2cmmedial margin : 0.5cmlateral margin : 3.5cmdeep margin : 0.7cm.b) received fibrofatty tissue measures 9x6x2cm. largest lymph node measures 1.5x1x0.4cm. cut surface show fatty infiltration.c) received fibrofatty tissue measures 4x3.5x1cm. largest lymph node measures 1x0.5x0.2cm. entire tissue processed.,a)lumpectomy wide excision :lumpectomy bed : the section shows few ducts are seen showing residual ductal carcinoma in situ with surrounding parenahyma shows degenerated cells lymphocytes plenty of giant cells. there in no evidence of residual viable invasive ductal carcinoma. lymphovascular invasion not present perinerual invasion not present.resected margins :superior margin : free of tumor.inferior margin : free of tumor.medial margin : shows are vessel with tumor emboli close to margin. however not present at inked margin.lateral margin : free of tumor.deep margin : free of tumor.lymph nodes axillary :b)right axillary lymphnodes level i ii : 14 nodes no deposits of tumor.c) level iii lymph nodes : 4 nodes no deposits of tumor.,a)lumpectomy bed :few ducts are seen showing residual ductal carcinoma in situ. surrounding parenchyma show post treatment changes. no evidence of viable invasive carcinoma.lymphovascular invasion not presentperineural invasion is not presentresected margins :superior margin : free of tumor.inferior margin : free of tumor.lateral margin : free of tumordeep margin :free of tumormedial margin : one vessel show tumor emboli close to margin. however inked margin margin is free of tumor.advised ihc markers cd34 and ki67axillary lymph node :b)right axillary level i ii lymph nodes : 14 nodes no deposits of tumor.c)level iii lymph nodes : 4 nodes no deposits of tumor.
MR1705661,right breast spiculated mass carcinoma breast.,right breast lump biopsy.,received multiple greywhite linear cores measuring 0.5 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in tubules and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with lymphocytic infiltrates.,right breast lump biopsy:invasive carcinoma nst grade 1.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9
MR1705682,right breast lump multifocal birads 4c.,right breast mass biopsy.,received multiple fragmented grey white linear cores measuring 0.3 to 0.1cm. entire tissue processed.,section shows breast parenchyma harboring an infiltrating lesion arranged in and tubules. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. stroma shows desmoplasia. few foci show pseudo traching of tumor cells.,right breast mass biopsy :invasive carcinoma nst grade 2.modified br score is 7 9.tubular formation : 3nuclear pleomorphism : 2mitotic activity : 2 7 9
MR1705688,left breast mass narmo birads iiic.,left breast mass biopsy.,received multiple greywhite linear cores measuring 0.5 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in tubules and sheets. the cells are ovoid having moderate amount of cytoplasm and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with lymphocytic infiltrates. areas of hemorrhage and necrosis are seen.,left breast mass biopsy:invasive carcinoma nst grade 2.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 ductal carcinoma in situ solid and cribriform pattern noted.
MR1705690,left breast lump carcinoma.usg birads iv.,biopsy from left breast.,received multiple fragmented grey white to grey brown linear cores measuring 0.3 to 0.6cm. entire tissue processed.,linear cores of breast paranchyma infiltrated by a neoplasm arranged as islands and sheets. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. atypical mitosis seen.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 8 9 grade 3.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR1705712,left breast lump carcinoma.,left breast lump biopsy.,received multiple grey white linear cores measuring 0.8 to 1cm. entire tissue processed.,section shows breast parenchyma with a lesion arranged in tubules nests and cords. cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows desmoplasia. mitosis is discerned.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score 6 (3+2+1).
MR1705727,right breast lump p o carcinoma breast,biopsy from right breast,received multiple grey white to grey brown linear cores measures 0. 8 to 1cm.entire tissue is processed,section shows linear cores of breast parenchyma harboring a lesion arranged in nests cordsand islands comprising of large atypical cells with pleomorphic round to oval hyperchromatic nuclei prominent nucleoli and scanty to moderate eosinophilic cytoplasm. brisk mitotic activity is discerned.ductal carcinoma in situ is noted with comedonecrosis. stroma shows extensive lymphoproliferative infiltrate areas of necrosis and hemorrhage,right breast biopsy:invasive carcinoma nst grade 3mbr score 8 9tubule formation 3nuclear pleomorphism 2mitotic figures 3 8 9 ductal carcinoma in situ is identified with comedonecrosis.
MR1705734,left breast mass carcinoma left breast.,left breast mass biopsy.,received multiple fragmented grey white linear cores measuring 0.4 to 0.1cm. entire tissue processed.,tissue is suboptimally processed.section shows linear cores of fibrocollagenous tissue with a lesion arranged in sheets and vague tubules. the cells are ovoid with inconspicuous cellular margins granular eosinophilic cytoplasm and ovoid nucleus. extensive inflammatory infiltrate and multinucleate giant cells and epitheloid clusters are seen.,left breast mass biopsy :suggestive of invasive carcinoma nst.nuclear grade i.note : tissue is suboptimally processed it is preferable to repeat biopsy for special investigation
MR1705755,case of right breast carcinoma.,a) right breast lumpectomy.b) revised inferior margin.c) axillary lymphnode dissection.,a) received fibrofatty tissue measures 5.5x3.5x2.8cm. skin ellipse measures 2.5x1cm. cut surface show grey yellow lesion measures 1.8x1.5x1cm.distance from margins :superior : 1cm.inferior : 0.8cm.medial : 0.4cm.lateral : 1.5cm.deep : 0.4cm.b) received fibrofatty tissue measures 4.5x3.5x1cm. entire tissue processed.c) received fibrofatty tissue measures 9x6x2.5cm. largest lymph node measures 1.8x1.5x1cm. isolated 20 nodes.,a) right breast lumpectomy.tumor bed : the sections show fibrotic area focal necrosis with plenty of giant cells inflammatory cells consisting of lymphocytes plasma cells histocytes and granulation tissue post treatment changes. there is no evidence of residual viable tumor .resected margins :superior margin : free of tumor.inferior margin : free of tumor.medial margin : free of tumor.lateral margin : free of tumor.deep margin : free of tumor.b) revised inferior margin : free of tumor.c) right axillary lymph node dissection :20 nodes no deposits of tumor.,right breast conservative surgery :no residual viable tumor.all resected margins are free of tumor.revised inferior margin is free of tumor. lymph nodes :20 nodes no deposits of tumor.
MR1705757,left breast mass carcinoma left breast,biopsy from left breast mass,received multiple grey white linear cores measures 0.8 to 1cm. entire tissue is processed,section show linear cores of tissue showing adipocyte lobules and hyalinisation with a lesion arranged asinfiltrating cords sheets nests with retraction of stroma around the nests. the cells have mild to moderatelypleomorphic hyperchromatic nuclei and moderate amount of cytoplasm. stroma show desmoplasia and scatteredstromal cells and congested hyalinised blood vessels native breast parenchyma is not seen,left breast core biopsy:invasive ductal carcinoma grade iimbr score 6 9tubule formation 3nuclear pleormorphism 2mitotic figures 1 6 9
MR1705794,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received 5 grey white to grey brown linear cores measures 0.5 0.7cm. entire tissue processed.,section shows fragmented linear cores of tissue infiltrated by neoplastic cells arranged in nests and clusters with areas of mucin pools . ductal carcinoma in situ component is noted cribriform and solid pattern. the tumor cells have round nucleus dispersed chromatin and moderate cytoplasm.,biopsy from right breast lump:suggestive of invasive carcinoma with mucinous areas.
MR1705805,left breast suspicious lesion birads 4b,biopsy from left breast lump,received multiple grey white to grey brown linear cores measures 0.8 to 1cm. entiretissue is processed,section shows linear cores of breast tissue infiltrated by a lesion arranged in nests cords and trabeculae.cells have round to oval hyperchromatic nuclei and scanty cytoplasm. mitotic figures 2 3 hpf. stroma shows extensive fibrosis and lympholplasmacytic infiltrates. ductal carcinoma in situ with comedonecrosis is seen. thickened hyalinised blood vessels are noted. large areas of necrosis seen.,left breast lump biopsy:invasive carcinoma nst grade 3mbr scores 8 9tubule formation 3nuclear pleomorphism 2mitotic figures 3 8 9
MR1705894,left breast lump carcinoma breast.,left breast biopsy.,received 4 greywhite to greybrown linear cores measuring 1.2 to 1.3cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a lesion arranged in nests cords and islands consisting of atypical cells with round to oval pleomorphic hyperchromatic nuclei and moderate eosinophilic to clear cytoplasm. stroma shows extensive fibrosis and lymphocytic infiltrate. lymphovascular invasion is identified.,left breast biopsy:invasive ductal carcinoma grade 2.mbr score (3+2+2) : 7 9.
MR1705898,right breast mass.,biopsy from right breast trucut.,received 6 grey white linear cores measures 1 to 1.3cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a cellular lesion arranged in sheets comprising of polygonal cells with round to oval pleomorphic hyperchromatic nuclei few with prominent nucleoli and moderate eosinophilic cytoplasm. mitotic figures 13 10hpf. stroma shows fibrosis and hyalinised blood vessels.,trucut biopsy from right breast invasive carcinoma nst grade 3.mbr score 3+2+3 8 9.
MR1705900,left breast lump carcinoma breast.,left breast lump core biopsy.,received six grey white linear cores measuring 0.7 to 1.0cm. entire tissue processed.,section shows tumor cells in nests cords and tubular pattern. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1705923,right breast mass birads 4 c.,right breast mass core biopsy.,received three grey white to grey brown linear cores measuring 0.7 to 1.0cm. entire tissue processed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast mass core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1705938,pet ct omentum peritoneal nodules present.,biopsy from omental lesion.,received 5 greywhite to greybrown linear cores measuring 0.5 to 0.7cm. entire tissue processed.,fragmented linear cores of tissue exhibiting nests and islands and glandular configuration of round to oval neoplastic cells demonstrating moderate nuclear pleomorphism and eosinophilic cytoplasm amidst a fibrocollagenous stroma.,biopsy from omental lesion:metastatic adenocarcinoma.possible primaries include: stomach lung breast.suggest ihc.
MR1705939,multiple lung nodules metastatic.known case of carcinoma breast post mrm (2005).,biopsy from left lung lesion.,received multiple fragmented grey white to grey brown linear cores measuring 0.4 to 0.6cm. entire tissue processed.,linear cores of lung parenchyma infiltrating by neoplastic glands lined by cuboidal to columnar cells exhibiting moderate nuclear pleomorphic and eosinophilic cytoplasm amidst areas of necrosis and fibrocollagenous stroma. foci of metaplastic ossification noted,biopsy from left lung lesion :invasive adenocarcinoma. primary . metastasis from breastsuggest ihc.
MR1705995,right breast lump carcinoma.,right breast biopsy.,received four grey white linear cores measuring 1.0 to 1.4cm. entire tissue processed.,section shows breast parenchyma with proliferation of glands having both myoepithelial and epithelial layers. there are also presence of nests and cords of cells which are large with clear cytoplasm and peripheral placed hyperchromatic nuclei. areas of hyalinisation seen.,right breast biopsy :invasive ductal carcinoma.mbr score:7 9 (grade ii)
MR1706010,carcinoma left breast.,left breast lump biopsy.,received four grey white linear cores measuring 1 to 1.4cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a lesion arranged in nests cords and islands comprising of atypical cells with round to oval pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderate eosinophilic cytoplasm. stroma shows extension fibrosis.,left breast lump biopsy :invasive ductal carcinoma grade ii.modified br score is 7 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1706082,left breast lump carcinoma breast ( post chemo).,biopsy from left breast.,received 1 linear cores measures 0.8 to 1cm. entire tissue processed.,section studied shows multiple cores of breast parenchyma shows large areas of sclerosis harboring neoplastic cells arranged as islands and focal clusters. the lesional cells have abundant amount of cytoplasm moderate pleomorphic hyperchromatic nuclei. mitosis are discerned. areas of hemorrhage noted.,biopsy from left breast:invasive carcinoma nst residual disease in a known case of carcinoma breast post chemo.
MR1706093,left breast lesion.,biopsy from left breast lesion.,received 5 grey white linear cores measures 1 to 1.3cm. entire tissue processed.,section shows ores of breast parenchyma harboring a lesion arranged in nests and cords consisting of atypical cells with round to oval pleomorphic dark nuclei inconspicuous nucleoli and moderate eosinophilic cytoplasm. mitotic figures 7 8 10hpf. stroma shows fibrosis hyalinised blood vessels and lymphoplasmacytic infiltrate.,biopsy from left breast lesion:invasive carcinoma nst grade 2.mbr score 3+2+2 7 9.
MR1706096,left breast lung carcinoma.,left breast biopsy.,received four grey white to grey brown linear cores measuring 0.7 to 1.0cm. entire tissue processed.,section shows fragments of tissue demonstrating an infiltration lesion arranged in sheets and nests. the cells have pleomorphic round to oval with hyperchromatic nuclei inconspicuous nucleoli and scant to moderate cytoplasm. mitotic activity is discerned.,left breast biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1706106,right breast lump carcinoma breast.,right breast lump core biopsy.,received 5 grey white to grey yellow linear cores measures 0.5 to 1cm. entire tissue processed.,section shows core of breast tissue infiltrated by tumor cells in nests sheets and tubules . individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1706115,known case of carcinoma right breast.left breast lump carcinoma complex fibroadenoma.,biopsy from left breast lump.,received four grey white linear cores measuring 0.6 to 0.8cm. entire tissue processed.,linear cores of breast tissue harboring foci of adenosis. the ducts are benign lined by bilayered epithelium.,fibroadenosis biopsy from left breast lump.no evidence of malignancy.
MR1706168,left breast lump carcinoma.,biopsy from left breast.,received four grey white to grey brown linear cores measuring 0.7 to 0.8cm.entire tissue processed.,linear cores of breast parenchyma harboring a neoplasm arranged as clusters and islands. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. foci of high grade comedo ductal carcinoma in situ seen.,invasive ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 foci of high grade ductal carcinoma in situ.
MR1706184,right breast lumpectomy,a) right breast right modified radical mastectomy.b) revised superior skin margin,a) received in : formalinprocedure : mastectomy laterality : right total dimensions : medial lateral 19cm superficial deep 4cm superior inferior 19cmskin ellipse : 11x7cm nipple :normal scar surgical defect : not seentumor : single tumour size : 1.8 x 1.3 x 1 cm location of tumor : upper inner quadrant margins of tumor : illdefined deep margin : 0.2 cm muscle : absent adjacent breast : fibrofatty tissue axillary tail : 8 x 7 x 2.5 cmsize of largest node : 1 x 1 x 0.6 cm cut surface shows fatty infiltrationrepresentative sections are submitted.b) received single skin covered linear soft tissue bits measures 8 cm.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromaticnuclei and moderate amount of cytoplasm. lymphovascular invasion or perineural invasionis not seen.,a) right breast right modified radical mastectomy (post lumpectomy) :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). tumour is unifocal and is located in the upper inner quadrant. tumor measures 1.8 cm in greatest dimension ductal carcinoma in situ is not seen. lymphovascular invasion is not identified. perineural invasion is not identified. posterior resection margin is free of tumor. nipple and areola is free of tumor.lymph nodes : twenty three lymph nodes are identified negative for malignancy(0 23). pathological stage : pt1cn0
MR1706230,left breast lump possibility of carcinoma breast,biopsy from left breast,received multiple grey white linear cores measures 1 to 2cm.entire tissue is processed,linear cores of tissue exhibiting neoplastic lesion arranged in cords and nests consisting of round to oval cells harboring vesicular nuclei showing moderate nuclear pleomorphism and eosinophilic cytoplasm with intervening fibrocollagenous stroma. mitotic figure are discerned. there are focal aggregates of lymphocytic infiltrate.,biopsy from left breast lesion:invasive ductal carcinoma grade iitubule formation 3nuclear pleomorphism 2mitotic figures 2 mbr 7 9
MR1706263,lump in left breast,a) left sentinel lymph node biopsyb) left breast conservative surgery wide local excisionc) revised superior margind) revised deep margin,a) received fibrofatty tissue measuring 2.5x2x0.5cm largest lymph node measures 1.5x1x0.5cmcut surface shows grey white with fatty infiltrationb) received lumpectomy specimen measuring 5.5x4x3.5cm cut surface show grey white mucinous areameasures 2x1.5x1.2cm located at the following distances from the respective margins: superior margin 1.3cminferior margin 1.8cmmedial margin 1cmlateral margin 3cmdeep margin 0.8cmc) received single fibrofatty tissue measures 5x3x2cm one surface inkedd) received single fibrofatty tissue measures 3x2x2cm one surface inked,sections reveal breast parenchyma harboring a neoplastic lesion arranged in tubular configuration floating in pools of mucin. the neoplastic cells exhibit moderate nuclear pleomorphism and pale eosinophilic cytoplasm,a) left sentinel lymph node biopsy:2 lymph nodes are negative for malignancy(0 2)b) left breast conservative surgery wide local excision:mucinous carcinoma grade itubule formation 2nuclear pleomorphism 2mitotic figures 1 5 9 tumor measures 2cm in the greatest dimensionlymphovascular and perineural invasion are not identifiedmargins : superior margin usual ductal hyperplasiainferior margin free of tumormedial margin free of tumorlateral margin free of tumordeep margin usual ductal hyperplasiac) revised superior margin : free of tumord) revised deep margin free of tumor
MR1706367,right breast lumpoutside biopsy poorly differentiated malignant tumor,biopsy from right breast lump,received multiple grey white linear cores measures 0.6 to 1.2cm,section shows linear cores breast parenchyma harboring a lesion arranged in bundles and fascicles. cells have oval elongated to bizarre hyperchromatic nuclei with scant to moderate cytoplasm with tapering ends. fragment atypical mitoses seen. no ductal cells are seen.,right breast lump biopsy:poorly differentiated malignancythe possibilities considered are1. metaplastic carcinoma2. malignant mesenchymal lesion(sarcoma)
MR1706404,left carcinoma breast,left modified radical mastectomy,received in : formalinprocedure : mastectomy laterality : left total dimensions : medial lateral 13cm superficial deep 3.5cm superior inferior 16cm skin ellipse : 12x8cm nipple : show retractionscar surgical defect : not seentumor : single grey white areas : 3.8x2x2cm location : central quadrant deep margin : 0.6cm muscle : present measures 2x1cm adjacent breast : fibrofatty axillary tail : 12x6x2cmtotal number of nodes : 20lymph nodessize of largest node : 1x0.8x0.5cm cut surface shows grey white,section shows breast parenchyma with tiny foci of atypical ovoid cellular clustershaving moderate amount of cytoplasm vesicular nucleus and prominent nucleoli. stroma shows extensive areas of desmoplasia with lymphocytes plasma cells histiocytes and giant cells. emperiopoiesis and fat necrosis is noted,left breast left modified radical mastectomy: residual intraductal carcinoma. tumor measures 0.2cm in greatest dimension and is located in the central quadrant. lymphovascular invasion not seenperineural invasion not seenposterior resected margin is free of tumornipple and areola is unremarkablelymph nodes: 20 lymph nodes metastasis: one (01 20). summary :left mrm residual focus of intraductal carcinoma status post excision biopsynodal metastases 1 20.no perinodal spread seen.
MR1706413,left breast mass birads 4c,biopsy from left breast mass,received multiple grey white linear cores measures 0.8 to 1cm.entire tissue is processed,section shows linear cores of breast parenchyma harboring a lesion arranged in sheets nestsand cords. cells have hyperchromatic nuclei and moderate amount of cytoplasm. stromal desmoplasia is noted with moderate lymphomonocytic infiltrate,biopsy from left breast mass:invasive ductal carcinoma grade 2mbr score 6(3+2+1)tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1706421,case of carcinoma breast with pleural lesion.,biopsy from pleural lesion.,received multiple grey white linear cores of measures 1 to 1.2cm. entire tissue processed.,section shows linear cores of fibroconnective tissue harboring an infiltrating lesion arranged in acinar glandular and micropapillary pattern with central necrosis. the cells are ovoid having moderate amount of cytoplasm and hyperchromatic pleomorphic nucleus brisk mitotic activity is noted. stroma shows desmoplasia.,biopsy from pleural lesion:metastatic adenocarcinoma. primary in lung.suggest ihc.
MR1706427,right breast lump possibility of carcinoma breast,biopsy from right breast lump,received multiple grey white to grey brown linear cores measures 0.8 to 1.0cm.entire tissueis processed,sections studied shows linear cores of breast parenchyma harboring a lesion arranged in nests sheets and cords. cells have hyperchromatic nuclei and moderate amount of cytoplasm. stromalhyalinisation noted,right breast lump biopsy:invasive carcinoma nst grade 2mbr score 7 9 (3+2+2)tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1706446,left breast mass fnac duct cell carcinoma,biopsy from left breast mass,received multiple grey white to grey brown linear cores measures 0.8 to 1.2cm.entire tissue is processed,section shows linear cores of breast parenchyma with a lesion arranged in nests sheets and islands. cells have hyperchromatic to vesicular nuclei with prominent nucleoli and abundant eosinophilic cytoplasm.brisk mitoses noted. stromal hyalinisation and lymphocytic aggregates seen.,left breast mass biopsy:invasive carcinoma nst grade iimbr score 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1706526,right breast lesion carcinoma,biopsy from right breast lesion,received multiple grey white to grey yellow linear cores measures 1 to 1.5cm.entire tissue is processed,section shows linear cores of breast parenchyma infiltrated by a lesion arranged in nests islands and cords of atypical cells with round to oval pleomorphic dark nuclei prominent nucleoli and moderate amount of eosinophilic cytoplasm. brisk mitosis noted. stroma shows fibrosis focal areas of necrosis lymphoplasmacytic infiltrate,right breast biopsy:invasive carcinoma nst grade 2mbr score 7 9tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1706538,right breast mass,biopsy from right breast mass,received multiple grey white linear cores measures 1 to 1.5cm.,section shows cores of breast parenchyma harboring a lesion arranged in nests islands and vague tubules comprising of markedly pleomorphic cells with large bizarre hyperchromatic nuclei prominent nucleoli and moderate eosinophilic cytoplasm. multinucleate giant cells are seen. stroma shows fibrosis and lymphoplasmacytic infiltrate,right breast lesion biopsy:invasive carcinoma nst grade 3mbr score 2+3+3 8 9tubule formation 2nuclear pleomorphism 3mitotic figures 3 8 9
MR1706695,left breast mass.,left breast core biopsy.,received seven grey white to grey brown linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in tubules nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy :invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1706725,left breast lump possibility of carcinoma breast,biopsy from left breast.,received multiple grey white to grey yellow linear cores measures 0.6 to 1.2cm.entire tissueis processed.,section shows linear cores of tissue exhibiting nests and cords of cells with round to oval hyperchromatic moderately pleomorphic nucleus prominent nucleoli and scanty cytoplasm. atypical mitotic figures discerned.stroma shows inflammatory infiltrate areas of fibrosis and desmoplasia.,infiltrating ductal carcinoma biopsy from left breast.grade 2 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1706757,carcinoma left breast,a) sentinel lymph nodesb) wide excision lump,a) received fibrofatty tissue measures 3x2x1cm.largest lymph node measures 1.1x0.8x0.5cm.lymph nodes stained blue measures 0.6x0.6x0.5cm isolated 5 nodesb) received lumpectomy specimen measures 6x5x3.5cm skin ellipse measures 3x1cm cut surfaceshows grey white lesion measures 1.5x1.5x1.2cm located at the following distance from the respectivemargins:superior margin 1cminferior margin 1cmmedial margin 0.8cmlateral margin 2.3cmdeep margin 1.5cm,a) sentinel lymph nodes:5 nodes no deposits of tumorb) wide excision lumptumor invasive ductal carcinomagrade tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9 ductal carcinoma insitu few ducts show ductal carcinoma in situ solid type measures 0.5cm(low grade)lymphovascular invasion not presentperineural invasion not presentresected margins: superior margin free of tumorinferior margin free of tumormedial margin free of tumorlateral margin free of tumordeep margin free of tumor,a) sentinel lymph nodes:5 nodes no deposits of tumorb) wide excision lump:invasive ductal carcinomamaximum dimension of tumor is 1.5cmnuclear grade iiductal carcinoma in situ few ducts show ductal carcinoma in situ measures 0.5cm low gradelymphovascular invasion not presentall resected margin free of tumorpathological stage: pt1n0
MR1706777,left breast mass with calcification birads 5 lesion.,left breast mas biopsy.,received six grey white to grey brown linear cores measuring 1 to 1.5cm. entire tissue processed.,section shows cores of breast parenchyma infiltrated by a lesion arranged in nests and cords. cells are pleomorphic with round to oval dark nuclei few with prominent nucleoli and moderate eosinophilic cytoplasm. stroma shows desmoplasia lymphoplasmacytic infiltrate and focal areas of comedonecrosis seen.,left breast mass biopsy :invasive carcinoma no special type (nst) grade 2.modified br score is 6 9.tubular formation : 3nuclear pleomorphism : 2 mitotic figures : 1 6 9
MR1706812,case of left breast carcinoma.,a) left breast lumpectomy.b) left axillary lymph node dissection.,a) received lumpectomy specimen measures 9x6x1.5cm. skin ellipse measures 6x1cm. cut surface shows no obvious lesion only ill defined fibrotic areas noted measures 1.5x1x0.5cm. distance from margins :superior : 0.5cm.inferior : 3cm.medial : 3cm.lateral : 4cm.deep : 1.5cm.b) received fibrofatty tissue measures 15x12x4cm. largest lymph node measures 2x1x0.5cm. cut surface shows fatty infiltrate.,a) left breast lumpectomy :multiple section examined shows no residual viable tumor. few atropic ducts are seen. post chemotherapy changes in form of histiocytic and lymphocytic inflammation with presence of few giant cells are noted. deep margin is free of tumor. resected superior inferior medial and lateral margin are free of tumor. b) left axillaryy lymph node dissection :five out of thirteen lymph nodes show metastatic deposits of viable invasive ductal carcinoma. perinodal spread present.,a) left breast lumpectomy :no residual viable tumor.resected margin are free of tumor.b) left axillary lymph node dissection :five out of thirteen lymph nodes show metastatic deposits of viable invasive ductal carcinoma.
MR1706817,right breast mass birads five lesion.,right breast core biopsy.,received grey white linear cores measuring 1 to 1.5 cm. entire tissue processed.,section shows tumor cells in cords and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1706818,left breast retro nodal hard mass.,left breast biopsy.,received five grey white to grey yellow linear core measuring 0.8 to 1cm. entire tissue processed.,section from breast parenchyma shows linear cores o tissue fragments demonstrating a neoplastic lesion arranged in trabeculae sheets. the cells have round to oval pleomorphic hyperchromatic nuclei with moderate cytoplasm. mitotic activity are seen. areas of hyalinisation noted.,left breast biopsy :suggestive of invasive ductal carcinoma grade ii.modified br score is 7 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1706819,right breast ulcerated mass.,right breast biopsy.,received four grey white linear cores measuring 1.0 to 1.2cm. entire tissue processed.,section shows linear cores of breast infiltrated by a neoplastic lesion arranged in nests cords and sheets comprising of round to oval cells with pleomorphic dark nuclei few with prominent nucleoli and moderate to abundant eosinophilic cytoplasm. stroma shows desmoplasia lymphoplasmacytic infiltrate and areas of necrosis.,right breast biopsy :invasive ductal carcinoma grade 2.modified br score is 7 9 grade 2.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 area of necrosis seen.
MR1706840,left breast lump possibility of carcinoma breast,biopsy from left breast lump,received multiple grey white to grey brown linear cores measures 0.8 to 1cm.entire tissue isprocessed,section shows linear cores of breast parenchyma harboring a lesion arranged in tubules nests papillae islands consisting of dark nuclei and abundant eosinophilic to vacuolated cytoplasm. binucleate and multinucleate cells are seen. also seen homogenous eosinophilic secretions in the lumen of tubules. occasional mitosis is noted. stroma shows hyalinisation,left breast biopsy:invasive carcinoma probably secretory carcinomanuclear grade 2
MR1706845,left breast lump.,left breast lesion biopsy.,received multiple grey white to grey yellow linear cores measuring 0.5 to 1.2cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue with an infiltrating cellular lesion arranged in sheets and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic pleomorphic nucleus with prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with lymphocytes plasma cells and foamy macrophages. areas of hemorrhage and necrosis seen. numerous crush artifacts are noted.,left breast lesion biopsy :invasive carcinoma no special type grade 2.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 areas of necrosis seen.
MR1706861,known case of carcinoma breast (2012.),biopsy from abdominal well lesion.,received six grey white to grey brown linear core measuring 1 to 1.5cm. entire tissue processed.,linear cores of tissue demonstrating irregular and confluent neoplastic glands lined by low columnar cells exhibiting moderate nuclear pleomorphism and eosinophilic cytoplasm with many lumina showing areas of necrosis. intervening stroma is desmoplastic.,biopsy from abdominal well lesion :metastatic deposits of adenocarcinoma. git gall bladder.suggest ihc.
MR1706882,left breast lump.,biopsy from left breast.,received 4 grey white to grey brown linear cores measures 0.6 to 1.3cm. entire tissue processed.,section shows cores of breast parenchyma harboring a neoplastic lesion arranged in nests and islands consisting of pleomorphic cells with round to oval dark nuclei inconspicuous nucleoli and moderate eosinophilic cytoplasm. extensive ductal carcinoma in situ seen cribriform and comedonecrosis pattern. stroma shows extensive necrosis and desmoplasia.,biopsy from left breast:invasive carcinoma no specific type grade 2 with extensive ductal carcinoma in situ cribriform and comedonecrosis pattern.modified bloom richardson score is 7 9.tubular formation 3.nuclear pleomorphism 2.mitotic figures 2. 7 9
MR1706916,left breast lesion.,left breast biopsy.,received five grey white linear core measuring 0.8 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords trabeculae and in sheets. the cells have round to oval pleomorphic hyperchromatic nuclei with moderate cytoplasm. there are areas of ductal carcinoma in situ noted. adjacent stroma shows hyalnisation.,left breast biopsy :invasive ductal carcinoma with ductal carcinoma in situ grade ii.modified br score is 7 9.tubular formation : 3nuclear pleomorphism : 3mitotic figures : 1 7 9
MR1706958,known case of carcinoma breast treated.,biopsy from abdominal mass.,received multiple grey white to grey brown linear cores measures 0.5 to 1.2cm. entire tissue processed.,section shows linear cores of fibrofatty tissue infiltrated by islands cords occasional tubules and trabeculae of neoplastic cells exhibiting moderate to marked nuclear pleomorphism round to oval hyperchromatic nuclei irregular nuclear contours and moderate amount of eosinophilic cytoplasm.mitotic figures 2 3 10hpf is discerned.few cells show binucleation and multinucleation. stroma shows areas of necrosis desmoplastia and hyalinized blood vessels.,biopsy from abdominal mass:metastatic deposits. breast from elsewhere.report on ihc to follow.
MR1706987,right breast lump.,right breast lump core biopsy.,received seven grey white to grey brown linear core measuring 1 to 1.4cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrative lesion arranged in sheets and island. the lesional cells have moderate amount of clear to eosinophilic cytoplasm high n:c ratio pleomorphic hyperchromatic nuclei. few large cells with bizarre nuclei are also seen. mitotic figures are discerned. stroma shows lymphocytic infiltration.,right breast lump core biopsy :invasive carcinoma nst grade ii.modified br score is 8 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 8 9
MR1707011,left breast lump.,left breast lump core biopsy.,received five grey white to grey yellow linear core measuring 0.5 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords. trabeculae and in islands. the lesional cells have high n:c ratio pleomorphic hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. stroma shows marked desmoplastic reaction. areas of hemorrhage are seen. mitotic figures are discerned.,left breast lump core biopsy :features suggestive of invasive ductal carcinoma nuclear grade ii.
MR1707040,right breast mass.carcinoma breast.,right breast core biopsy.,received 6 grey white linear core measures 0.8 to 1.2cm. entire tissue processed.,section shows tumor cells in tubular pattern nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy:invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1707041,left breast lump p o carcinoma breast.,left breast lump biopsy.,received 5 grey white linear core measuring 0.8 to 1cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring lesion arranged in cords tubules and nests lesion comprising of round to oval moderately pleomorphic hyperchromatic nuclei and moderate cytoplasm. adjacent parenchyma shows dsemoplasia.areas of ductal carcinoma in situ noted.mitosis 3 4 10 hpf.,left breast lump biopsy:suggestive of invasive carcinoma nst grade i.mbr score is 5 9.tubule formation : 2nuclear pleomorphism : 2mitotic activity : 1 5 9
MR1707047,left breast lump.,left breast lump biopsy.,received five grey white linear core measuring 0.8 to 1.2cm. entire tissue processed.,section shows breast parenchyma harboring lesion arranged in nest tubules comprising of round to oval moderately pleomorphic hyperchromatic nuclei and moderate cytoplasm. adjacent stroma show desmoplasia lymphocytic infiltrate. mitotic figures 3 4 10hpf. lymphovascular invasion and perineural invasion not identified. ductal carcinoma in situ with comedonecrosis seen.,left breast lump biopsy :suggestive of invasive carcinoma nst grade ii.modified br score is 6 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 ductal carcinoma in situ with comedonecrosis seen.
MR1707048,lump in left breast,a) left lumpectomyb) left modified radical mastectomyc) left level iii axillary nodes,a) received lumpectomy measures 6x5x3cm cut surface shows grey white lesion measures 2x2x1.5cm distancefrom nearest inked margin is 0.5cmb) received in : formalinprocedure : left modified radical mastectomy post lumpectomy laterality : left total dimensions : medial lateral 20cm superficial deep 5cm superior inferior 21cmskin ellipse : 14x11cm nipple and areola : normal scar surgical defect : below nipple and areola measures 6.5x5clumpectomy bed : 6.5x5x4.5cm tumor not identified .however few grey white areas seen location of tumor : lower quadrant deep margin : 1.5cm muscle : absent adjacent breast : fibrofatty tissue axillary tail : 7x6x3cmsize of largest node : 1.8x1.5x1.5cm cut surface shows grey whitec) received fibrofatty tissue measures 2.5x2x1cm,multiple sections show a cellular infiltrating lesion arranged in sheets. the cells are pleomorphic havingmoderate amount of cytoplasm vesicular pleomorphic nucleus and prominent nucleoli. mitotic figures arediscerned. few bizarre forms with multilobated nuclei are noted. occasional tumor giant cells are noted. stroma shows desmoplasia with myxoid change and lymphoplasmacytic infiltrates. areas of hemorrhageand necrosis are seen. adjacent breast shows atypical ductal hyperplasia solid ductal carcinoma in situfibroadenosis and dilated ducts,left breast left modified radical mastectomy: sarcomatoid metaplastic carcinoma grade iii. modified br score is 9 9.tubule formation: 3 nuclear pleomorphism: 3mitotic figures: 3tumor measures 6 cm in greatest dimension and is located in the lower quadrant. ductal carcinoma in situ is seen solid and cribriformlymphovascular invasion identifiedperineural invasion indeterminateposterior resection margin is free of tumorlymph nodes: 14 lymph nodes metastasis: 2(2 14) . size of the largest tumor foci is 1.2cmextranodal extension is seensummary : left mrm metaplastic carcinoma grade iiilymph nodes 2 14
MR1707067,carcinoma left breast,a) sentinel lymphnodesb) left mastectomyc) level iii nodesd) post slnb axillary clearance,a) received multiple fibrofatty tissue measures 4x4x1cm larger lymph node measures 2x1x1cm cut surface shows grey white stained blueb) received in : formalin procedure : mastectomy laterality : left total dimensions : medial lateral 20cm superficial deep 4.5cm superior inferior 19cm skin ellipse : 13.5x9cm nipple : retractedscar surgical defect : not seentumor : single tumour size : 4.5x3x2.5cm location of tumor : central quadrant retroareolar margins of tumor : ill defined deep margin : 1cm muscle : absent adjacent breast : fibrofatty axillary tail : absentc) level iii lymph nodes: received fibrofatty tissue measures 2x2x1cmd) post sentinel lymph node biopsy axillary clearance:received fibrofatty tissue measures 7x7x4cm largest lymph node measures 0.8x0.8x0.5cm cut surface is unremarkable,a)sentinel lymph nodes 3 nodes show metastatic deposits of tumor out of 7 nodesb)left breast left mastectomy: tumor: maximum dimension of tumor is 4.5cminvasive ductal carcinoma measure 3cm grade iiductal carcinoma in situ solid type low grade measures 1.5cm modified br score is 7 9 .tubule formation: 3nuclear pleomorphism: 2mitotic figures: 2tumor is located in the central quadrant retroareolar region. ductal carcinoma in situ present low grade measures 1.5cmlymphovascular invasion is presentperineural invasion is presentposterior resection margin is free of tumornipple and areola is unremarkablelymph nodes: 7 lymph nodes no metastatic deposits of tumorlevel iii 1 node no metastatic deposits of tumor,left modified radical mastectomy invasive ductal carcinoma grade iimaximum dimension of tumor is 4.5cminvasive ductal carcinoma 3 cm ductal carcinoma in situ 1.5cm lymphovascular invasion presentperineural invasion presentundersurface resected margin free of tumornipple and areola unremarkablesentinel lymph nodes: 3 nodes show metastatic deposits of tumor out of 7 nodesaxillary lymph nodes 7 nodes no deposits of tumorlevel iii lymph nodes one node no deposits of tumortotal 3 out of 15 nodes show metastatic deposits of tumorpathological stage : pt2n1
MR1707085,left breast lump.,left breast lump core biopsy.,received five grey white to grey brown linear core measuring 1 to 1.8cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords trabeculae and sheets. the lesional cells have high n:c ratio markedly pleomorphic hyperchromatic to vesicular nuclei with prominent nucleoli in some and moderate amount of eosinophilic cytoplasm. stroma shows marked sclerosis. frequent mitotic figures noted.,left breast lump core biopsy :invasive carcinoma nst.grade ii.modified br score is 7 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1707103,right breast lump carcinoma breast.,right breast lump biopsy.,received 5 greywhite linear core measuring 1 to 1.8cm. entire tissue processed.,section shows breast parenchyma harboring a lesion arranged in sheets nests trabeculae and cribriform pattern. cells have moderately pleomorphic hyperchromatic nuclei few with prominent nucleoli and moderate amount of cytoplasm. adjacent stroma shows lymphoplasmacytic infiltrate and fibrosis. areas of necrosis noted. mitoses discerned.,right breast lump biopsy:invasive carcinoma nst grade 2.mbr score 6 (3+2+1).areas of necrosis seen.
MR1707108,right breast lump.,right breast lump core biopsy.,received four grey white to grey brown linear core measuring 1.2 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords trabeculae and nests admixed with areas of hemorrhage. the lesional cells have high n:c ratio pleomorphic hyperchromatic nuclei inconspicuous nucleoli and scant amount of eosinophilic cytoplasm. stroma shows fibrosis. mitotic figures are discerned.,right breast lump core biopsy :invasive ductal carcinoma nst grade ii.modified br score is 7 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1707112,lump in left breast.,left breast lump core biopsy.,received seven grey white to grey brown linear core measuring 0.3 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in diffuse sheets and nests admixed with mixed inflammatory infiltrate. the lesional cells have high n:c ratio markedly pleomorphic hyperchromatic to vesiculae nuclei with prominent nucleoli in some and moderate amount of eosinophilic cytoplasm. stroma shows marked sclerosis. frequent mitotic figures noted.,left breast lump core biopsy :invasive carcinoma nst with medullary like areas. grade iii.modified br score is 8 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR1707151,left breast lump p o carcinoma breast.,left breast biopsy.,received multiple grey white to grey brown linear cores measuring 0.5 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a lesion arranged in tubules nests islands and cords of atypical cells with pleomorphic round to oval dark nuclei irregular nuclear contours inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. brisk mitosis discerned. stroma shows desmoplasia. no necrosis identified.,left breast biopsy :invasive ductal carcinoma grade 3.modified br score is 8 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR1707166,right breast lump p o carcinoma breast).,left breast lesion biopsy.,received 4 greywhite to greyyellow linear core measuring 1 to 1.2cm. entire tissue processed.,section shows breast parenchyma harboring a lesion arranged in nests sheets trabeculae and infiltrating into adjacent stroma. cells have moderately pleomorphic hyperchromatic nuclei and moderate amount of cytoplasm. adjacnet stroma shows desmoplasia and lymphoplasmacytic infiltrate. atypical mitoses noted.,left breast lesion biopsy:invasive carcinoma nst grade 2. mbr score : 6 (3+2+1).suggestive of recurrence in an operated case of carcinoma breast
MR1707181,right breast lump p o carcinoma breast.,right breast lump biopsy.,received seven fragmented linear cores measuring 0.3 to 0.8cm. entire tissue processed.,section shows cores of breast parenchyma with few benign glandular tissue and fibrosis.,right breast lump biopsy :no evidence of malignancy in the material submitted.
MR1707189,left breast lump.,biopsy from left breast.,received 5 grey white to grey yellow linear cores measures 1 to 1.5cm. entire tissue processed.,section shows breast parenchyma harboring a lesion arranged in nests cords and sheets consisting of atypical cells with round to oval dark nuclei inconspicuous nucleoli and moderate amount of eosinophilic to pale granular cytoplasm. mitotic figures 4 5 10hpf. stroma shows numerous plasma cells.,biopsy from left breast:invasive carcinoma no specific type nuclear grade 2.
MR1707243,right breast lump.,biopsy from right breast lesion.,received 4 grey white to grey brown linear cores measures 0.8 to 1.2cm. entire tissue processed.,section from breast shows an infiltrating lesion arranged in nests and sheets consisting of atypical cells with round to oval dark nuclei and moderate eosinophilic cytoplasm. stroma shows fibrosis and lymphocytic infiltrate mf : 8 9 10hpf. dcis with necrosis infiltrated.,biopsy from right breast lesion:invasive ductal carcinoma grade 2.modified bloom richardson score 7 9.tubular formation 3.nuclear pleomorphism 2.mitotic figures 2. 7 9 focus of dcis with necrosis seen.
MR1707256,left breast lump p o carcinoma breast.,left breast lump.,received four grey white linear core measuring 1 to 1.2m. entire tissue processed.,sections studied from multiple cores show tumor arranged in sheets cords and nests. individual cells have increase n:c ratio hyperchromatic and moderate pleomorphism. intervening fibrocollagenous stroma show lymphoplasmacytic infiltration.,biopsy from left breast lump.infiltrating ductal carcinoma biopsy left breast.modified br score is 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic activity : 1 6 9
MR1707267,known case of right breast carcinoma .left breast lump p o carcinoma breast.,left breast lump biopsy.,received six grey white linear cores measuring 0.5 to 1.4cm. entire tissue processed.,section show cores of breast parenchyma harboring cellular lesion arranged in sheets tubules. the lesional cells are round to oval having hyperchromatic nuclei exhibiting marked pleomorphism few showing prominent nucleoli and scant cytoplasm .bizarre cells present. intervening stroma is elastotic. mitotic figures 10 12 10hpf. areas of hemorrhage noted.,left breast lump biopsy :invasive ductal carcinoma grade 3.modified br score is 8 9.tubule formation : 2nuclear pleomorphism : 3mitotic figures : 3 8 9
MR1707296,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white to grey yellow linear cores measures 0.6 to 1.3cm. entire tissue processed.,section shows breast parenchyma harboring a lesion arranged in tubules cords and trabecular. neoplastic cells have round to oval hyperchromatic nuclei and scant to moderate cytoplasm. adjacent stroma shows desmoplasia.,biopsy from left breast lump:invasive carcinoma no special type grade 2.modified bloom richardson score 5 9.tubular formation 2.nuclear pleomorphic 2.mitotic figures 1. 5 9
MR1707352,right breast lump p o carcinoma breast.,right breast lump core biopsy.,received four grey white to grey yellow linear cores measuring 0.5 to 1.0cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests lying in pools of extracellular mucin. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy :invasive carcinoma with mucinous features grade 2. modified bloom richardson score is 6(3+2+1).
MR1707377,left beast mass.,biopsy from left breast.,received 7 grey white to grey brown linear cores measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords nests and sheets. the cells have round to oval hyperchromatic nuclei with moderate amount of cytoplasm. intervening stroma shows lymphoplasmacytic infiltrate. intervening stroma shows fibrosis.,biopsy from left breast:invasive carcinoma nuclear grade 2.modified bloom richardson score 6 9.tubular formation 3.nuclear pleomorphic 2.mitotic figures 1. 6 9
MR1707382,right breast lump p o carcinoma right breast.right axillary node.,biopsy from right axillary node.,received three grey white to grey brown linear cores measuring 0.6 to 1.2cm. entire tissue processed.,linear cores of tissue showing anasomosing bands and nests of round to oval cells demonstrating moderate nuclear pleomorphism amidst fibrocollagenous stroma.,biopsy from right axillary node :metastatic carcinoma.
MR1707403,right breast lump p o carcinoma breast.,biopsy from right breast lesion.,received seven grey white to grey brown linear cores measuring 0.5 to 1.2cm. entire tissue processed.,fragmented linear cores of tissue exhibiting discreet nest and islands of round to ovalcells demonstrating vesicular nuclei moderate nuclear pleomorphism eosinophilic cytoplasm and notable mitotic activity surrounded by dense lymphoplasmacytic infiltrate.,biopsy from right breast lesion :ductal carcinoma in situ with suspicious areas of invasion.needs confirmation on ihc.
MR1707405,left breast lump p o carcinoma breast.,left breast biopsy.,received four grey white to grey yellow linear cores measuring 0.8 to 1.2cm. entire tissue processed.,section shows breast parenchyma harboring a neoplastic lesion arranged in cord tubules and in sheets. the cells have round to oval hyperchromatic nuclei with moderate cytoplasm. areas of fibrosis and hyalinization noted.,left breast biopsy :invasive ductal carcinoma grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1707407,right breast lump p o carcinoma breast.,biopsy from right breast lesion.,received 5 grey white to grey yellow linear cores measures 1 to 1.5cm. entire tissue processed.,linear cores of tissue demonstrating a neoplastic lesion arranged is sheets and tubular configuration consisting of round to oval cells exhibiting moderate nuclear pleomorphic and eosinophilic cytoplasm. mitotic figures are discerned. intervening areas show fibrovascular stroma.,biopsy from right breast lesion.invasive ductal carcinoma grade 2.modified bloom richardson score 6 9.tubular formation 2.nuclear pleomorphism 2.mitotic figures 2. 6 9
MR1707413,left breast lump p o carcinoma breast.,left breast biopsy.,received four grey white to grey brown linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows linear cores of breast tissue infiltrated by nests islands and cords of neoplastic cells with round to oval pleomorphic vesicular nuclei prominent nucleoli and moderate amount of eosinophilic cytoplasm. stroma shows desmoplasia and lymphoplasmacytic infiltrate. foci of necrosis noted.,left breast biopsy :invasive ductal carcinoma grade 2.modified br score is 7 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 foci of necrosis seen.
MR1707429,right breast lump p o carcinoma breast.,right breast biopsy.,received multiple grey white to grey yellow linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows breast parenchyma with extensive area of fibrosis and focal area shows ductal cells which are lined by myoepithelial layer. the cells have round to oval moderately pleomorphic nuclei and moderate amount of cytoplasm. lobular cancerization seen. few ducts shows adenosis.,right breast biopsy :ductal carcinoma in situ with occasional foci of lobular cancerization.
MR1707436,left breast mass carcinoma breast papillary carcinoma breast.,left breast mass biopsy.,received multiple grey white linear cores measuring 0.8 to 1.2cm. entire tissue processed.,section show multiple cores of breast parenchyma harboring infiltrative lesion arranged in cords and tubules. lesional cells are round to oval having hyperchromatic nuclei marked nuclear pleomorphism and scant cytoplasm. intervening stroma shows desmoplasia. mitotic figures 3 4 10hpf. focal necrosis noted.,left breast mass biopsy :invasive carcinoma grade 2.modified br score : 6 9.tubule formation : 2nuclear pleomorphism : 3mitotic figures : 1 6 9
MR1707484,carcinoma breast.,biopsy from left breast mass.,received multiple grey white linear cores measures 1 to 1.2cm. entire tissue processed.,h and e stained section shows linear cores of breast parenchyma showing an infiltrative lesion arranged in nests islands and sheets. the lesional cells are large with abundant eosinophilic cytoplasm pleomorphic vesicular nuclei with prominent nucleoli. few nuclei show hyperchromatic nuclei. stroma shows inflammatory infiltrate. adjacent breast shows features of florid adenosis.,biopsy from left breast mass:invasive ductal carcinoma. grade 2. modified bloom richardson score 7(3+2+2).
MR1707520,right breast lump carcinoma breast.,biopsy from right breast lesion.,received multiple grey white linear cores measuring 1 to 1.5cm. entire tissue processed.,linear cores of tissue exhibiting a neoplastic lesion arranged in tubular configuration ( anguleted is native) and nests consisting of cuboidal to oval ells demonstrating mild nuclear pleomorphism and eosinophilic cytoplasm. there are areas shows nests of tumor hyperchromatic nuclei.,biopsy from right breast lesion :invasive carcinoma. tubular. neuroendocrine carcinoma invasive carcinoma nos.
MR1707523,right chest wall lesion.,right breast lesion biopsy.,received multiple grey white to grey brown linear cores measuring 0.5 to 1.3cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue harboring an infiltrating cellular lesion arranged in sheets. the cells are ovoid plasmacytoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. stroma shows desmoplasia with interspersed areas exhibiting lymphoplasmacytic infiltrates. occasional mitotic figures are discerned.,right breast lesion biopsy :invasive carcinoma nst grade 2.modified br score 6 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures :1 6 9
MR1707553,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey yellow linear cores measures 1.2 to 1.5cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue harboring infiltrating lesion arranged in tubules sheets and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with lymphocytic infiltrates. areas of hemorrhage and necrosis seen.,biopsy from right breast lump:invasive carcinoma no special type grade 2.modified bloom richardson score 8 9.tubular formation 3.nuclear pleomorphism 2.mitotic figures 3 8 9 areas of necrosis seen.
MR1707633,right breast lump possibility carcinoma breast.,right breast lump core biopsy.,received 6 grey white to grey brown linear cores measures 1 to 1.5cm. entire tissue processed.,section shows tumor cells in cords and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score 6(3+2+1).
MR1707654,left breast lump possibility carcinoma breast.,left breast lump core biopsy.,received multiple grey white to grey yellow linear cores measures 1 to 1.5 cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1707668,carcinoma left breast lump.,biopsy from left breast.,received multiple gray white to gray black linear cores measures 0.5 to 0.8 cm. entire tissue processed,section shows cores of tissue harboring a lesion arranged in islands nests and sheets of typical cells with normal to oval pleomorphic hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. few cells show centrally plaual dark nuclei and abundant clear cytoplasm. intervening the tumor islands fibrocollaginous bonds are noted. mitotic figures 10 12 10 hpf. stroma shows desmoplasia and lymphoplasmaplastic infiltrate.,biopsy from left breast. invasive carcinoma nuclear grade 2probably papillary variant.
MR1707675,right breast lump carcinoma breast.,right breast biopsy.,received multiple grey white to grey brown linear cores measuring 0.4 to 0.8cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a lesion arranged in tubules cords and islands case of plasmacytoid cells with angulated dark peripherally pushed nuclei and moderate amount of eosinophili cytoplasm. mitotic figures 2 3 10hpf. stroma shows extensive desmoplasia.,right breast biopsy :invasive carcinoma no special type grade 1.modified br score is 5 9.tubular formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9
MR1707706,right breast lump possibility of carcinoma breast.,right breast lump.,received four grey white linear core measuring 1 to 1.2cm. entire tissue processed,section from right breast lump shows sheets of pleomorphic cells showing hyperchromatic nucleus prominent nucleoli and eosinophilic cytoplasm. areas of necrosis seen. brisk mitosis noted.,invasive carcinoma nst grade iii right breast.modified br score is 8 9.tubular formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1707761,right breast lump possibility of carcinoma breast,biopsy from right breast lump,received multiple grey white linear cores measures 1 to 1.4cm.entire tissue is processed,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in cords and nests. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with chronic inflammatory infiltrate. ductal carcinoma in situ areas are noted,right breast lump biopsy:invasive carcinoma nst grade 2tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9 ductal carcinoma in situ papillary and cribriform pattern noted
MR1707771,left breast lump p o carcinoma breast.,biopsy from left breast lump.,received multiple linear cores measuring 1 to 1.2cm. entire tissue processed.,multiple cores studied show tumor cells arranged in cords sheets and tubules. individual cells show mild to moderate amount of cytoplasm. intervening fibrocollagenous stroma show lymphocytic infiltrates. lymphovascular invasion seen.,infiltrating ductal carcinoma.modified br score is 6 9 grade 2.tubule formation : 2nuclear pleomorphism : 2mitotic activity : 2 6 9
MR1707785,carcinoma left breast,a) lumpectomy left breast conservative surgeryb) axillary clearance specimen,a) received lumpectomy specimen measures 9x6.5x6cm skin ellipse measures 6.5x3.5cm nipple present and unremarkable cut surface shows a mucinous lesion measures 3x2x2cm and is located at the following distances from the respective margins: superior margin 0.8cminferior margin 5cmmedial margin 4.5cmlateral margin 2cmdeep margin 3cmb) axillary clearance:received fibrofatty tissue measures 4.5x3.5x1.5cm largest lymph node measures 1x0.8x0.5cm cut surface shows grey white,a) lumpectomy left breast conservative surgery:tumor :tumor is composed of pleomorphic oval to polyhedral cells with eccentric to central hyperchromaticnucleus and intracellular mucinsurrounding the tumor mucinous areas are presentmucinous carcinomagrade tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9 nuclear grade iilymphovascular invasion is not presentductal carcinoma in situ not presentperineural invasion not presentresected margins: superior margins free of tumorinferior margin free of tumormedial margin free of tumorlateral margin free of tumordeep margin free of tumorlymph nodes 12 nodes no deposits of tumor,a) lumpectomy left breast conservative surgery:mucinous carcinomamaximum dimension of the tumor is 3x2x2cmnuclear grade iiductal carcinoma not presentlymphovascular invasion not presentperineural invasion not presentall resected margins are free of tumorb) axillary clearance 12 nodes no deposits of tumor pathological stage :pt2n0
MR1707786,right breast lump.carcinoma breast.,right breast core biopsy.,received multiple grey white to grey yellow linear cores measures 1 to 1.2cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1707810,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey brown linear cores measures 0.5 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating cellular lesion arranged in cords and tubules. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. extensive areas of desmoplasia with chronic inflammatory infiltrate are seen.,biopsy from right breast lump:invasive carcinoma no specific type grade 2.modified bloom richardson score 7 9.tubular formation 3nuclear pleomorphic 2mitotic figures 2 7 9
MR1707818,right breast lump p o carcinoma breast.,right breast lump core biopsy.,received multiple grey white to grey brown linear core measuring 0.3 to 1cm. entire tissue processed.,section show breast parenchyma harboring a spindle cell neoplasm composed of cells arranged in fascicles. the cells show moderate amount of cytoplasm oval to spindle shaped vesicular nuclei. interspersed vascular channels are seen.,right breast lump core biopsy :features suggestive of spindle cell lesion favoring benign phyllodes tumor.suggest excision of the lump for further confirmation.
MR1707834,right breast mass.,biopsy from right breast mass.,received multiple grey white to grey yellow linear cores measures 0.5 to 1m. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating cellular lesion arranged in sheets and nests. the cells are pleomorphic having moderate amount of cytoplasm hyperchromatic pleomorphic nucleus with prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with chronic inflammatory infiltrates. areas of hemorrhage and necrosis are seen.,biopsy from right breast mass:invasive carcinoma no specific type grade 3.modified bloom richardson score 8 9.tubular formation 3nuclear pleomorphic 2mitotic figures 3 8 9 areas of necrosis seen.
MR1707836,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received multiple grey white to grey yellow linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of breast tissue infiltrated by a neoplastic lesion arranged in cords indianfile trabecular and islands consistent of atypical cells with round to oval dark nuclei prominent nucleoli and moderate amount of eosinophilic cytoplasm. some cells shows eccentrically placed round to oval nuclei and vacuolated cytoplasm (signet ring). stroma shows extensive areas of fibrosis and hyalinisation along with few areas showing targetoid appearance of neoplastic cells loosely arranged around ducts.,biopsy from right breast:invasive carcinoma no special type nuclear grade 2.modified bloom richardson score 7 9.tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1707837,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white to grey yellow linear cores measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue harboring an infiltrating cellular lesion arranged in cords and sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma shows desmoplasia with inflammatory infiltrates.,biopsy from left breast lump:invasive carcinoma nst no specific type grade 2.modified bloom richardson score 6 9.tubular formation 3nuclear pleomorphic 2mitotic figures 1 6 9
MR1707878,right breast lump.,right breast lump biopsy.,received multiple grey white to grey brown linear core measuring 1 to 1.5cm. entire tissue processed.,section shows cores of breast parenchyma infiltrated by islands and cords of atypical cells showing round to oval hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. mitotic figures are discerned 1 2 hpf. ductal carcinoma in situ identified. comedonecrosis pattern. stroma shows extensive desmoplasia and lymphoplasmacytic infiltrate.,right breast lump biopsy :invasive ductal carcinoma grade 3.modified br score is 8 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures 3 8 9 ductal carcinoma in situ with comedonecrosis seen.
MR1707905,left breast lump possibility of carcinoma breast,biopsy from left breast lump,received multiple grey white to grey brown linear cores measures 0.5 to 0.8cm.entire tissue isprocessed.,section shows linear cores of breast parenchyma with proliferation ducts lined by luminal ovoid cells having moderate amount of cytoplasm and bland appearing nucleus. an abluminal intactmyoepithelial layer. stroma shows desmoplasia with scattered lymphocytes.,left breast lump biopsy:suggestive of sclerosing adenosis.no evidence of malignancy in the material submitted.
MR1707908,carcinoma breast with ductal carcinoma in situ.,biopsy from left breast lesion.,received multiple grey white to grey brown linear cores measuring 0.8 to 1.2cm. entire tissue processed.,fragmented linear cores of breast parenchyma exhibiting few ducts lined by round to oval neoplastic cells demonstrating moderate nuclear pleomorphism. mitotic figures and areas of necrosis are noted.,biopsy from left breast lesion :ductal carcinoma in situ high grade.please correlate with mammographic findings.
MR1707911,right breast speculated mass carcinoma breast.,biopsy from right breast.,received multiple grey white linear cores measuring 0.6 to 1cm. entire tissue processed.,sections from needle core biopsy of breast shows clusters and single file arrangement of cells. the cells show hyperchromatic nucleus and eosinophilic cytoplasm. background show extensive sclerosis.,invasive carcinoma no special type.right breast.modified br score is 6 9 grade ii.tubular formation : 3nuclear pleomorphism : 2mitosis figures : 1 6 9
MR1707922,left breast lump.,left breast lump core biopsy.,received four grey white to grey yellow linear cores measuring 1 to 1.2cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1707943,carcinoma breast.,biopsy from left breast.,received 5 linear cores measures 0.5 to 1cm. entire tissue processed.,linear cores of breast tumor infiltrated by a neoplasm arranged as sheets islands and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. areas of necrosis seen.,biopsy from left breast:invasive ductal carcinoma grade 2modified bloom richardson score 7 9.tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1707971,left breast lump p o carcinoma breast.,biopsy from left breast.,received 5 grey white to grey brown linear cores measures 0.8 to 1.3cm. entire tissue processed.,section from breast shows tubules cords and islands of atypical cells with round to oval pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. tumor island are seen with surrounding retraction spaces. occasional mitosis discerned. focal ares of necrosis seen. stroma shows desmoplastic changes.,biopsy from left breast.invasive ductal carcinoma grade 2bloom richardson score is 6 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures :1 6 9
MR1707984,right breast lump.,right breast lump core biopsy.,received four linear cores measuring 1 to 1.4cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests and papillary pattern. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. areas of necrosis are seen.,right breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1707995,left breast lump possibility of carcinoma breast,biopsy from left breast lump,received multiple grey white linear cores measures 0.5 to 1.3 cm. entire tissue is processed,section showing multiple linear fragments of breast tissue showing lesion arranged in glands and tubules.cells showing the lesion are round to oval with hyperchromatic nuclei and abundant cytoplasm. the fibrocollagenous tissue shows inflammatory cells composed of lymphocytes.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1707997,carcinoma right breast ( post nact).,a) right breast conservative surgery.b) solitary thyroid nodule right lobec) left lobe of thyroid.d) right axillary lymph nodes.,a) received lumpectomy specimen measuring 8.8x7.5x3cm. skin ellipse measures 5x2.5cm shows a linear scar measuring 2.5cm in length. section shows a grey white lesion measuring 2.5x2x2cm. distance from margins :superior : 2cm.inferior : 2.5cm.medial : 1.8cm.lateral : 2.5cm.deep : 0.8cm.b) received single lobe of thyroid with attached isthmus altogether measures 4.5x3.5x2cm. lobe measures 4.5x2.5x2.0cm isthmus measures 2.5x1x0.5cm. cut surface shows single well defined grey white lesion with granular areas measuring 1.8x1.5x1.5cm no areas of calcification necrosis. adjacent thyroid shows colloid filled cystic areas. nearest inked margin is 0.1cm away.c) received single lobe of thyroid measures 4x2.4x2cm. outer surface is nodular and irregular. cut surface is unremarkable.d) received fibrofatty tissue measures 8x7x3cm. largest lymph node measures 1.5x1x0.8cm. cut surface shows fatty infiltration.,a) right breast conservative surgery :wide local excision :tumor bed : residual viable tumor present. the sections show highly pleomorphic tumor consisting of large polyhederal cells with pleomorphic hyperchromatic nucleus plenty of mitotic figures and marked degree of anisocytosis.tubular formation : 3nuclear pleomorphism : 3mitotic figures : 3 9 9 nuclear grade iiilymphovascular invasion : present.ductal carcinoma in situ : not present.resected margins: superior margin free of tumor.inferior margin free of tumor.medial margin free of tumor.lateral margin free of tumor.deep margin free of tumor.b) solitary thyroid nodule right lobetumor : multiple section from the tumor show pleomorphic cells with ground glass appearance of the nucleus and nuclear groove. the cells are arranged in papillary pattern and follicular pattern.capsular invasion is present.vascular invasion is indeterminate.the inked surface is 0.1cm from the tumor.extrathyroid extension is not present.c) left lobe of thyroid:the sections show normal thyroid follicles. there is no evidence of malignancy.d) right axillary lymph nodes:one node shows metastatic deposits of tumor out of 13 nodes.perinodal spread not present.,a) right breast wide excision (post nact):residual viable tumor present.poorly differentiated carcinoma high grade.nuclear grade iii.lymphovascular invasion : present.perineural invasion : present.ductal carcinoma in situ : not seen.all resected margins are free of tumor.d) right axillary lymph node:one node shows metastatic deposit of tumor out of 13 nodes. perinodal spread is not present.b) solitary thyroid nodule right lobe of thyroid:papillary carcinoma.moderately differentiated.capsular invasion is present.lymphovascular invasion : indeterminate.c) left lobe of thyroid : normal thyroid follicles.
MR1708019,right breast lump p o carcinoma breast.,biopsy from right breast.,received multiple grey white linear cores measures 0.6 to 1.2cm. entire tissue processed.,section shows fibrocollagenous tissue harboring an infiltrating lesion arranged in nests and sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. occasional mitotic figures noted. stroma shows desmoplasia with areas of hemorrhage and necrosis.,biopsy from right breast.infiltrating ductal carcinoma.modified bloom richardson grade 2.tubular formation 3nuclear pleomorphic 2mitotic figures 1 6 9
MR1708096,mass in right breast carcinoma breast,biopsy from right breast mass,received multiple grey white linear cores measures 1 to 1.2cm.entire tissue is processed,section shows cores of breast parenchyma infiltrated by a lesion arranged in nests islands with intervening areas of mucin. neoplastic cells are round to oval hyperchromatic with moderatepleomorphism and moderate amount of eosinophilic cytoplasm. mitotic figures 2 3 10hpf. no necrosis identified,invasive carcinoma with mucinous areas biopsy from right breastgrade 2tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1708109,left breast lump possibility of carcinoma breast,biopsy from left breast lump,received multiple grey white linear cores measures 1 to 1.3cm. entire tissue is processed,section shows linear cores of breast parenchyma harboring an infiltrating cellular lesion arrangedin sheets and vague tubules. the cells are ovoid having moderate amount of cytoplasm hyperchromaticnucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with chronicinflammatory infiltrate. areas of hemorrhage and necrosis are seen,left breast lump biopsy:invasive carcinoma nst grade 2tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9 areas of necrosis seen
MR1708188,fibroadenoma right breast .,lumpectomy,received already grossed nodular mass measures 3x2.5x2cm outer surface is nodularon cut section well circumscribed grey white distance from nearest ink margin lt 0.1cm.received 2 slides labelled as b 427 17.,lumpectomy cut sections show focal areas invasive ductal carcinoma is present.nuclear grade ii and in other areas ductal carcinoma in situ present. surrounding ducts show periductal lymphocytic infiltration.,invasive ductal carcinoma nuclear grade ii with ductal carcinoma in situthe margin cannot be commented with grossing done irregularly.
MR1708214,right breast lump possibility of carcinoma breast,biopsy from right breast lump,received multiple grey white linear cores measures 0.6 to 1cm. entire tissue is processed,linear cores of breast tissue harboring a cellular lesion arranged in sheets and islands consisting of atypical cells with round to oval dark nuclei prominent nucleoli and moderateamount of eosinophilic cytoplasm. brisk mitosis noted. intervening stroma shows lymphoplasmacytic infiltrate. areas of necrosis seen,infiltrating ductal carcinoma biopsy from right breastgrade 2 tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1708285,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.5 to 1cm.entire tissue is processed.,section shows linear cores of breast parenchyma harboring an infiltrating cellular lesion arrangedin nests and vague tubular pattern. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with chronic inflammatory infiltrates. areas of hemorrhage and necrosis seen.,biopsy from left breast lump:invasive carcinoma nst grade ii.tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR1708315,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received multiple grey white linear cores measures 0.5 to 1.2cm.entire tissue is processed.,section shows linear cores of breast parenchyma harboring an infiltrating cellular lesion arranged in nests and sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with chronic inflammatory infiltrates. areas of hemorrhage and necrosisare seen.,right breast lump biopsy:invasive carcinoma nst grade 3tubule formation 3nuclear pleomorphism 2mitotic figures 2 8 9 areas of necrosis seen.
MR1708363,right breast lump possibility of carcinoma breast,biopsy from right breast lump,received multiple grey white to grey yellow linear cores measures 1 to 1.4cm.entire tissue is processed,section shows linear cores of breast parenchyma harboring an infiltrating cellular lesion arrangedin nests and sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma shows desmoplasiawith chronic inflammatory infiltrates. areas of hemorrhage and necrosis are seen.,right breast lump biopsy:invasive carcinoma nst grade 2tubule formation 3nuclear pleomorphism 2mitotic activity 2 7 9
MR1708383,right breast lump p o carcinoma breast.,right breast lump biopsy.,received six grey white linear cores measuring 0.2 to 1.4cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a lesion arranged in nests trabeculae and cords. lesional cells show moderate pleomorphism with hyperchromatic nuclei few with prominent nucleoli. cells have moderate amount of eosinophilic to vacuolated cytoplasm. adjacent stroma shows hyalinization areas of necrosis hemorrhage few dilated branchial ducts with hyperplastic epithelium.,right breast lump biopsy :invasive ductal carcinoma grade 2.modified br score is 6 9.tubular formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 areas of necrosis seen.
MR1708425,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received multiple grey white linear cores measures 0.8 to 1cm.entire tissue is processed.,section shows linear cores of breast parenchyma infiltrated by cords and islands of atypical cellswith pleomorphic round to oval hyperchromatic nuclei inconspicuous nucleoli and moderate to abundant pale eosinophilic to clear cytoplasm. mitotic figures are discerned. stroma shows hyalinisation and fibrosis. numerous crush artefacts are noted.,right breast biopsy:invasive ductal carcinoma.grade 2tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1708427,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple linear cores measures 0.8 to 1cm.entire tissue is processed.,section shows cores of breast parenchyma infiltrated by linear strands of atypical cells exhibitingnuclear pleomorphism vesicular nuclei and irregular nuclear membrane inconspicuous nucleoli and moderate eosinophilic cytoplasm. few ring like cells seen. stroma shows mild inflammatoryinfiltrate.,left breast lump:invasive carcinoma with lobular features nuclear grade 1
MR1708492,carcinoma left breast post rx.,uterus cervix and bilateral adnexa hysterectomy with bilateral salpingo oophorectomy.,uterus dimensions: midline fundal serosa to ectocervix : 12cmmaximum intercornual :6cmmaximum anterior to posterior : 3cmcervix dimensions : 2.5x2cm vaginal cuff : absentcervix shape : normal right ovary : 3x2x1.5cm. cut surface cyst measures 0.5x0.5x0.5cmleft ovary : 3x2x2cm. cut surface cyst measures 1x1x1cmright fallopian tube : 4cmleft fallopian tube : 5cmright parametrium : 1x0.5x0.5cmleft parametrium : 1x0.5x0.5cmendometrium description:endometrial thickness : 2cmmyometrium description:myometrial depth : anteriorly 2.5 cm posterior 2cmleiomyoma : norepresentative sections are submitted.,section studied show endometrium with glands of varying size of few of which are cystically dilated lined by low columnar cells having basally place nucleus and prominent nucleoli in few. gland to stromal ratio is maintained. endometrial glands and stroma are seen in myometrium.,uterus cervix and bilateral adnexa hysterectomy with bilateral salpingo oophorectomy :endometrium : non secretory phase.myometrium : superficial adenomyosis.cervix : chronic non specific cervicitis.lower uterus segment : unremarkable.right ovary : corpus albicanti.left ovary : unremarkable.right and left fallopian tubes: unremarkable.right and left parametria : unremarkable.
MR1708493,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey brown linear cores measures 0.5x1cm.entire tissue is processed.,section showing infiltrative lesion arranged in lobules and glands. the cells are round to oval with abundanteosinophilic cytoplasm hyperchromatic nuclei and vesicular nuclei with prominent nucleoli. surrounding fibrocollagenous stroma showing abundant inflammatory cells composed lymphocytes and plasma cells.,biopsy from right breast lump:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1708531,right breast lump possibility of carcinoma breast.,right breast biopsy.,received multiple grey white linear cores measures 0.8cm to 1.1cm.entire tissue is processed.,section showing infiltrative lesion arranged in glands lobules and cribriform pattern. the cells are round to oval cells with abundant cytoplasm hyperchromatic nuclei fibrocollagenous stroma shows inflammation. cells composed of lymphocytes.,right breast lump core biopsy :invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1708534,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received 5 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section sows linear cores of fibroconnective tissue harboring on infiltrating lesion arranged in tubules and nests . the cells are ovoid having moderate amount of eosinophilic cytoplasm hyperchromatic nucleus and inconspicuous nucleoli. stroma shows extensive areas of desmoplasia with chronic inflammatory infiltrates.,biopsy from left breast lump:invasive carcinoma nst grade imodified bloom richardson score is 5 9tubular formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9
MR1708649,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.8x1.2cm. entire tissue processed.,section shows multiple cores of fibrous tissue harboring an infiltrating lesion arranged in sheets nests and focal papillary pattern. the cells are ovoid having moderate amount of cytoplasm. hyperchromatic nucleus and prominent nucleoli. brisk mitotic activity is seen. stroma shows desmoplasia with areas of hemorrhage.,biopsy from left breast lump:invasive carcinoma of no special type grade 3.needs ihc.note : invasive carcinoma of no special type (nst) commonly known as ductal carcinoma nst
MR1708674,usg located lesion right breast.,right breast lump excision.,received skin covered fibrofatty tissue measures 3x2x1.5cm skin ellipse measures 1x1cm.cut surface shows fibrotic area. closest ink margin 0.2cm.,multiple sections studied shows ducts lined with cuboidal epithelial cells with some of themshowing adenosis epithelial hyperplasia and intra ductal papillomatosis. the ducts are lined with outer myoepithelial cells. there is no evidence of ductal carcinoma in situ or invasivecarcinoma.,right breast lump:adenosis.epithelial hyperplasia.intraductal papillomatosis.note:advised to follow.
MR1708675,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received 6 grey white linear cores measures 0.8 to 1.2cm. entire tissue processed.,section shows breast parenchyma dispersed extensive areas of ductal cell in situe with cells exchibiting nuclear pleomorphism hyperchromatic nuclei and moderate eosinophilic cytoplasm. adjacent breast tissue shows adenosis myoepithelial hyperplasia usual ductal hypoplasia fibrocystic change and lobular cercenization,biopsy from left breast:extensive ductal carcinoma in situ( solid type) focus of invasion cannot be ruled out.suggest repeat biopsy.
MR1708686,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received multiple linear cores measures 0.8 to 1cm.entire tissue is processed.,section shows cores of breast parenchyma infiltrated by a lesion in cords and strands. cells arepleomorphic with vesicular nuclei irregular nuclear membrane prominent nucleolus and moderateeosinophilic to clear cytoplasm. stroma shows mild lymphocytic infiltration.,biopsy from left breast invasive carcinoma nst no special type grade 2mbr score is 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1708704,left breast mass carcinoma breast.,biopsy from left breast mass.,received linear cores measures 0.8 to 1.2cm.entire tissue is processed.,sections from the breast parenchyma show an infiltrative lesion arranged in tubules and cords.the cells exhibit mild nuclear pleomorphism hyperchromatic nuclei and moderate eosinophiliccytoplasm.,left breast:suggestive of invasive ductal carcinoma nuclear grade ii.
MR1708789,left breast lump possibility of carcinoma breast.,left breast biopsy.,received multiple linear cores measures 0.8 to 1.2cm.entire tissue is processed.,section shows cores of fibrofatty tissue infiltrated by a lesion arranged in nests cords and tubules. cells aremoderately pleomorphic with irregular vesicular nuclei inconspicuous nucleoli and moderate eosinophiliccytoplasm. interspersed are pools of mucin. stroma shows lymphocytic infiltrate.,left breast :invasive carcinoma with extracellular mucin pools.nuclear grade i.
MR1708810,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple linear cores measures 0.8 to 1.2cm.entire tissue is processed.,section shows linear cores of tissue harboring a neoplastic lesion arranged as nests cords andsheets. the cells demonstrate moderate nuclear pleomorphism and moderate cytoplasm. stromashows hyalinisation.,biopsy from left breast lump:invasive ductal carcinoma grade ii.mbr score is 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1708832,right breast lump possibility of carcinoma breast.,biopsy from right breast .,received 5 linear cores measures 0.6 to 0.8cm. entire tissue processed.,section shows fragmented linear cores of tissue with extensive areas of necrosis harboring few foci of nests and sheets of cells . the cells have round to oval hyperchromtic pleomorphic nucleus with scanty cytoplasm. keryorrhectic and few mitotic figures noted.,biopsy from right breast:invasive carcinoma grade ii.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitosis : 2 7 9 large areas of necrosis seen.
MR1708837,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received grey white to grey brown linear cores measures 0.5 to 1cm.entire tissue is processed.,section shows linear cores of tissue exhibiting diffuse sheets of cells with round to oval hyperchromaticmoderately pleomorphic nucleus prominent nucleoli and scanty cytoplasm.mitotic figures are discerned.areas of necrosis present.,infiltrating ductal carcinoma biopsy from left breast.grade 2 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9 areas of necrosis.
MR1708843,left breast lump carcinoma breast.,biopsy from left breast lump.,received 5 linear cores measures 0.8 to 1.2 cm. entire tissue processed.,section shows linear cores of breast tissue infiltrated by a cellular lesion arranged as cores and tubules. the cells have round to oval hyperchromatic moderately pleomorphic nucleus and scanty cytoplasm. stroma shows hyalinisation and desmoplasia.,biopsy from left breast:invasive ductal carcinoma grade ii.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism: 2mitosis : 2 6 9
MR1708858,left breast lump possibility of carcinoma breast.,biopsy from left breast .,received 5 linear cores measures 0.8 to 1cm. entire tissue processed.,section shows linear cores of tissue infiltrated by nests and sheets of cells with round to oval hyperchromatic moderately pleomorphic nucleus and moderate amount of eosinophilic to vacuolated cytoplasm. intervening stroma shows lymphocytic infiltrate and areas of fibrosis and necrosis. dcis with comedonecrosis seen.,biopsy from left breast:invasive ductal carcinoma grade ii.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitosis : 2 7 9 ductal carcinoma in situ with comedonecrosis seen.
MR1708873,carcinoma left breast,a) excised left breast lumpb) revised deep margin.c) sentinel lymph nodes,a) excised left breast lump:received wide local excision specimen measures 11x7.5x5cm cut surface of lesion measures 2x1.8x1.5cm.located at the following distances from the respective margins : superior margin 0.3cminferior margin 4.5cmmedial margin 4cmlateral margin 5cmdeep margin 1cm b) revised deep margin:received fibrofatty tissue measures 9x5x1cm with one surface lined with tied with thread.c) sentinel lymph nodes from left axilla:received multiple fibrofatty tissue measures 3x2x2cm largest lymph node measures 1.5x1x0.8cm cut surface shows grey white.,a) excised left breast lump:tumor : tumor is composed of pleomorphic oval to cuboidal cells with hyperchromatic nucleusinvasive ductal carcinoma measures 1.5 cm with focal areas of ductal carcinoma in situ.solid and cribriform measures 0.5cmgrade : tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9 nuclear grade iilymphovascular invasion not presentperineural invasion is not presentresected margins superior margin free of tumorinferior margin free of tumormedial margin free of tumorlateral margin free of tumordeep margin free of tumorb) revised deep margin:shows fibrofatty tissue free of tumorc) sentinel lymph nodes:4 nodes no deposits of tumor.,a) excised left breast lump:maximum dimension of tumor is 2x1.8x1.5cm.invasive ductal carcinoma measures 1.5cmductal carcinoma in situ measures 0.5cm (low grade)lymphovascular invasion not presentperineural invasion not presentall resected margin are free of tumoraxillary lymph nodes 4 nodes no metastatic deposits of tumorpathological stage : pt1n0.
MR1708891,left breast lump possibility of carcinoma breast.,biopsy from left breast .,received 7 linear cores measures 0.8 to 1.8cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a lesion arranged as cords and diffuse sheets. the cells have round to oval hyperchromatic nucleus moderately pleomorphic nucleoli and scanty cytoplasm. intervening stroma shows fibrosis and hyalinisation.,biopsy from left breast:invasive ductal carcinoma grade ii.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitosis : 2 7 9
MR1708949,left breast lump possibility of carcinoma breast.,left breast lump biopsy.,received multiple linear cores measures 0.8 to 1.2cm.entire tissue is processed.,section shows multiple cores of breast parenchyma harboring infiltrative lesion arranged in sheets nests tubules. the lesional cells are normal to oval having hyperchromatic nuclei prominent nucleoliand scant cytoplasm.occasional bizarre cells noted. intervening stroma shows lympho plasmacytic infiltrate. mitoses 12 15 10hpf is seen.,left breast lump biopsy:invasive ductal carcinoma grade 3 modified bloom richardson score is 9(3+3+3).
MR1708955,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.8 to 1cm.entire tissue is processed.,section shows benign breast tissue and fibrous stroma.,benign breast tissueno evidence of malignancy in the sections studied.
MR1709027,right breast carcinoma left breast intraductal lesion inflammatory papillary.,biopsy from left breast lesion.,received multiple fragmented greywhite lesion cores measuring 0.2 to 0.5cm. entire tissue processed.,needle core biopsy from left breast shows normal breast parenchyma. two cores show papillary lesion lined by cuboidal cells. the cells are monomorphic with round regular nuclear outline small nucleoli and eosinophilic cytoplasm.,suggestive of papillary neoplasm.needs confirmation on larger biopsy.
MR1709028,left axillary lesion axillary tail mass.,left axillary node.,received multiple grey white to grey yellow bits measures 1 1.4cm.,section shows cores of fibrofatty tissue with an infiltrative lesion arranged in cords and tubules. cellsexhibit mild nuclear pleomorphism hyperchromatic nuclei and moderate eosinophilic cytoplasm.stroma shows mild inflammatory infiltrate.,biopsy from left axillary node:metastatic carcinoma probably from breast primaryplease correlate clinically.
MR1709044,breast lump carcinoma breast.,biopsy from left breast.,received multiple grey white linear cores measures 0.5 to 1.2cm.entire tissue is processed.,linear cores of breast tissue harboring neoplasm arranged as clusters and sheets. the neoplasticcells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm.areas with mucin secretion are noted.,invasive carcinoma with mucinous areas biopsy from left breastgrade 2 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1709048,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.4x0.5cm.entire tissue is processed.,section shows linear cores of breast parenchyma with pericanalicular growth pattern exhibiting fociof slit like ducts lined by inner epithelial and outer myoepithelial layer. few dilated ducts also noted. stroma is mild hypercellular with bland spindle cells and occasional mitotic figures.,biopsy from left breast lump:biphasic epithelial neoplasm.the possibilities considered are1) phyllodes tumor probably benign.2) cellular fibroadenoma suggest wide excision and close follow up.
MR1709050,left breast lump possibility of carcinoma breast.,left breast lump biopsy.,received four linear cores measures 1 1.2cm.entire tissue is processed,section shows breast parenchyma infiltrated by a lesion arranged in diffuse sheets. cells arepleomorphic with round to oval vesicular nuclei prominent nucleoli and moderate eosinophilic cytoplasm. mitotic figures are discerned. stroma shows marked inflammatory infiltrate and necrosis. mucinous areas seen.ductal carcinoma in situ solid type noted.,left breast lump:invasive carcinoma nst grade iimbr score 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9 mucinous areas are seenductal carcinoma in situ solid type noted.
MR1709059,carcinoma right breast metastatic,a) tlh+bso.,a) uterus dimensions: midline fundal serosa to ectocervix : 8cmmaximum intercornual : 5.5cmmaximum anterior to posterior : 3cmcervix dimensions : 2.5x1.5cm.right ovary : 2.5x2x0.5cm. cut surface is unremarkable.left ovary : 2.8x1.5x0.5cm. cut surface is unremarkable.right fallopian tube : 5cm grossly unremarkable.left fallopian tube : 5cm. grossly unremarkable.right parametrium : 0.5x0.5x0.5cm.left parametrium : 0.5x0.5x0.5cm.endometrium descriptionendometrial thickness : 0.3cm. grossly no tumor seen.myometrium descriptionmyometrial depth : anteriorly 1cm.,a) section from endometrium shows glands in non secretory phase.section from cervix : unremarkable.section from bilateral ovaries : unremarkable.section from fallopian tubes : unremarkable.section from bilateral parametrium : unremarkable.,a) endometrium : non secretory phase.cervix : non specific chronic cervicitis.bilateral ovaries : unremarkable.bilateral fallopian tubes : unremarkable.bilateral parametrium : unremarkable.
MR1709072,left breast lump.,a) lumpectomy wide excision.b) revised inferior margin.c) revised lateral margin.d) lymph nodes.,a) received lumpectomy specimen measures 5x4.5x1.5 cm .cut surface show grey white lesion measures 2.5x2.2x1.2cm.located at the following distance from the respective margin: superior margin 1.2cm. inferior margin 0.6cm.medial margin 1.2cm.lateral margin 2 cm.deep margin 0.4 cm. lateral margin show grey white areas.b) received single fibrofatty tissue measures 2.5x1.5x0.8cm. entire tissue processed.c) received fibrofatty tissue measures 2.5x2.5x1.5cm.d) received fibrofatty tissue measures 5.5x3.5x1cm. largest lymph node measures 1.5x1x0.5cm. cut surface show grey white.10 nodes dissection.,a) lumpectomy wide excision:tumor is composed of pleomorphic cells with hyperchromatic nucleus with eosinophilic cytoplasm. invasive ductal carcinoma. maximum dimension of tumor is 2.5cm. invasive carcinoma is 2cm. ductal carcinoma in situ solid low grade measures 0.5cm.lymphovascular invasion not present.perineural invasion not present.modified bloom richardson grade 2.tubular formation 3.nuclear pleomorphic 2.mitotic figures 2 7 9 resected margins:medial margin free of tumor.lateral margin atypical epithelial hyperplasia.superior margin free of tumor.inferior margin atypical hyperplasia with adenosis.deep margin free of tumor.b) revised inferior margin:the section shows adenosis and fibrofatty tissue. free of tumor.c) revised lateral margin:the section shows adenosis and fibrofatty tissue. free of tumor.d) lymph nodes:10 nodes. no deposits of tumor present.,wide excision lumpectomy:invasive ductal carcinoma nuclear grade iimargin dissection of is 2.5cm.invasive carcinoma measures 2cm.dcis 0.5cm low grade.lymphovascular invasion not present.resected margins:medial margin free of tumor.lateral margin revised margin free of tumor.superior margin free of tumor.revised inferior margin free of tumor.deep margin free of tumor.lymph nodes 10 nodes. no deposits of tumor.
MR1709073,right breast lump possibility of carcinoma breast.,biopsy from right breast,received 3 grey white to grey yellow linear cores measures 1 1.2cm.entire tissue is processed.,section shows breast parenchyma with an infiltrative lesion arranged in cords. cells are small roundto oval with hyperchromatic nuclei and moderate cytoplasm.adjacent breast shows areas of ductal carcinoma in situ and usual ductal hyperplasia. stroma shows lymphocytic infiltrate.,right breast:invasive carcinoma nst nuclear grade ii.
MR1709094,right breast mass carcinoma,biopsy from right breast lesion.,received multiple grey white linear cores measures 0.5 to 1cm.entire tissue is processed.,section shows linear cores of tissue harboring an infiltrative lesion arranged in linear cords and nests and tubular pattern. the cells have round to oval hyperchromatic moderately pleomorphicnucleus and scanty cytoplasm. mitotic figures are discerned. stroma shows fibrosis and hyalinization.necrosis is seen.,biopsy from right breast:invasive ductal carcinoma grade 2mbr score is 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR1709117,right breast lump with ulceration p o carcinoma breast.,biopsy from right breast lump.,received multiple grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in sheets with tubular and in cords. the cells are round to oval hyperchromatic to vesicular nuclei few showing prominent nucleoli and moderate amount of cytoplasm. mitotic activity are noted. areas of hyalinisation are seen.,biopsy from right breast lump:invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9.tubular formation 3.nuclear pleomorphic 2.mitotic figures 1. 6 9
MR1709119,right breast lump possibility of carcinoma breast.,right breast lump biopsy,received multiple grey white linear cores measures 0.8 1cm.entire tissue is processed.,section show multiple cores of breast parenchyma occasional ducts are showing epithelial hyperplasiacomprising of oval to columnar cells showing stratification. no nuclear atypia. bridging is noted with nuclei are parallel to bridging occasional ducts are showing myoepithelial hyperplasia.,right breast lump biopsy:no evidence of malignancy.suggestive of gynaectomastia with micropapillary ductal hyperplasia.
MR1709125,known patient of carcinoma breast on chemotherapy.,debrided tissue from left hand dorsum.,received skin with eschar measures 4.5x4.2x0.3cm.,multiple sections examined show a partially ulcerated epidermis with overlying acute inflammatory exudate. the dermis shows extensive hyalinisation. the underlying subcutaneous tissue shows panniculitis with acute inflammatory infiltrate and necrosis. no atypical cells are seen.,debrided tissue from left hand dorsum:necrosed and hyalinised skin tissue with panniculitis.no evidence of malignancy in the sections studied.report on fungal stain to follow.
MR1709147,left breast mass carcinoma breast.,left breast.,received multiple grey white linear cores measures 0.8 to 1.2 cm. entire tissue is processed.,section showing infiltrative lesion arranged in glands sheets and nests. cells are round to oval withmoderate to abundant cytoplasm hyperchromatic nucleus fibrocollagenous stroma showing inflammatory cells composed of lymphocytes neutrophils and macrophages. mitoses 3 4 10hpf.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1709162,right breast lump p o carcinoma breast.,biopsy from right breast.,received multiple linear cores measures 1.2 to 1.4cm. entire tissue processed.,section shows linear cores of tissue fragment demonstrating a neoplastic lesion arranged in sheets and cords. the cells have round to oval vesicular nuclei few showing prominent nucleoli and abundant cytoplasm. mitotic figures are rare. areas of hyalinization and fibrosis seen. areas of dcis are seen.,biopsy from right breast:invasive ductal carcinoma grade i.modified bloom richardson score is 5 9.tubular formation 3.nuclear pleomorphism 1.mitotic figures 1. 5 9
MR1709191,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received multiple grey white linear cores measures 0.6 to 1.4cm.entire tissue is processed.,linear cores of breast tissue harboring a few neoplastic cells arranged as cords trabeculae and clusters.the cells have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,invasive carcinoma left breast.grade 2tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1709209,left breast lesion carcinoma.,biopsy from left breast lesion.,received multiple grey white to grey yellow linear cores measures 0.5 1.5cm.entire tissue isprocessed.,needle core biopsy from left breast lesion shows few cores showing neoplastic lesion and few showing extensive hyalinization. the cells are arranged in sheets small nucleoli and clear to eosinophilic cytoplasm. extracellular mucin pools seen. few cells show cytoplasmic mucin.,biopsy from left breast lesion:invasive carcinoma nos grade iimbr score 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1709364,right breast carcinoma,right breast biopsy.,received multiple grey white to grey yellow linear cores measures 0.3 1cm.entire tissue is processed.,section from right breast needle core biopsy shows sheets of neoplastic cells. the cells show large vesicular nucleus conspicuous nucleoli and eosinophilic cytoplasm.,invasive carcinoma nos.mbr score 7 9 grade iitubule formation 2nuclear pleomorphism 3mitotic figures 2 7 9
MR1709375,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.5 1.5cm.entire tissue is processed.,section shows linear cores of lymphoid tissue exhibiting follicles with germinal centers. focal areas show diffuse sheets of polymorphic population of cells comprising of plasma cells eosinophils few histiocytes and intermixed small to medium sized cells with hyperchromatic nucleus dispersed chromatin and scanty cytoplasm. occasional mitosis noted. no breast tissue identified.no granulomas or rs cells identified.,biopsy from left breast lump:dense plasmacytic and eosinophilic infiltrate nature.needs correlation with clinical findings.suggested in toto excision if clinically deemed necessary
MR1709403,right breast lump possibility of carcinoma breast.,right breast.,received multiple grey white to grey yellow linear cores measures 0.5 1.2cm.entire tissue is processed.,section shows cores of breast parenchyma harboring an infiltrative lesion arranged in diffuse sheets. cells are pleomorphic with vesicular nuclei prominent nucleoli and moderate cytoplasm. areas of necrosis karyorrhectic debris and desmoplasia noted.,right breast:infiltrating carcinoma nst grade iiimbr score 8 9tubule formation 3nuclear pleomorphism 3mitotic figures 2 8 9 areas of necrosis seen.
MR1709421,carcinoma left breast post lumpectomy.,left breast conserving surgery.a) sentinel lnd biopsy.b) wide local excision.,a) received fibrofatty tissue altogether measures 3x2x1cm. 4 lymph nodes largest measures 1.5xx1cm. cut surface fatty infiltration see isolated 4 lymph nodes. entire tissue processed.b) received a lumpectomy specimen measures 7x4x3cm. skin flap measures 5x2xcm. on serial slicing no tumor identified.distance from margins : not applicable.,,left breast.procedure : post lumpectomy breast conservative surgery.tumor : no residual tumor multiple sections examined show normal pharenchyma with focal inflammatory cell and histiocyte aggregates with foriegn giant cell reaction.lymphovascular invasion absent.perineural invasion absent.skin unremarkable.lymph nodes :sentinel lymph nodes dissection : (0 4).number examined : 4number involved : 0 margins : free of tumor
MR1709433,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received 5 grey white to grey yellow linear cores measures 0.5 to 1.5cm. entire tissue processed.,section shows breast parenchyma with an infiltrative lesion arranged in cords. cells are pleomorphic with dark nuclei and moderate cytoplasm. ductal cell in situ with comedo necrosis seen. stroma shows marked lymphocytic infiltrate.,biopsy from left breast:invasive carcinoma nst nuclear grade iiductal cell in situ with comedo necrosis seen.
MR1709438,right breast post mrm,biopsy from right chest wall lesion.,received multiple grey white linear cores measures 1 1.5cm.entire tissue is processed.,section shows linear cores of fibrocollagenous tissue and muscle bundles harboring an infiltrating lesion arranged in acinar pattern and in cords. the cells are ovoid having moderate amount of cytoplasmand hyperchromatic pleomorphic nucleus. stroma shows desmoplasia with lymphovascular infiltrates.perineural invasion is seen.,right chest wall lesion biopsy:recurrent invasive carcinoma nst grade 2mbr score 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9 perineural invasion is seen.
MR1709450,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received 4 linear cores measures 0.8 to 1cm. entire tissue processed.,section sows cores of breast tissue with an infiltrative lesion arranged in cords and nests . cells are pleomorphic with vesicular nuclei prominent nucleoli and moderate clear cytoplasm. ductal carcinoma in situ solid with comedo necrosis and cribriform type noted. stroma shows desmoplasia.,biopsy from right breast:infiltrating carcinoma nst grade iimodified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 ductal carcinoma in situ with comedo necrosis seen
MR1709471,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received 5grey white to grey brown linear cores measures 0.8 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a lesion arranged as tubules cores and nests. the cells are cuboidal to ovoid with hyperchromatic pleomorphic nucleus and moderate cytoplasm. stroma shows desmoplasia and lymphomononuclear infiltrate.,biopsy from right breast lumpinvasive ductal carcinoma grade 2modified bloom richardson score is 6 9.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1709490,metastatic carcinoma left breast.,biopsy of left breast lump.,received multiple grey white to grey yellow linear cores measures 0.5cm 1cm.entire tissue is processed.,section shows linear cores of fibroadipose tissue harboring an infiltrative lesion arranged as linearcords and discretely scattered cells. the cells have round to oval hyperchromatic pleomorphicnucleus and scanty cytoplasm. mitotic figures are 6 7 10hpf. ductal carcinoma in situ (cribriformpattern) noted. stroma shows inflammatory infiltrate and hyalinisation.,biopsy from left breastinvasive carcinoma nst grade 2mbr score 6 9tubule formation 3nuclear pleomorphism 2mitosis 1 6 9
MR1709496,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.5 0.8cm.entire tissue is processed.,section shows linear cores of breast parenchyma exhibiting proliferation of acinar and tubularstructures lined by a luminal epithelial layer and an abluminal myoepithelial layer.stroma shows desmoplasia.,benign proliferative breast disease.suggestive of fibroadenoma.no evidence of malignancy in the tissue submitted.
MR1709595,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received 4 grey white to grey yellow linear cores measures 0.5 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma exhibiting proliferation of ductular structures lined by inner epithelial and other myoepithelial layer. few dilated ducts with luminal eosinophilic secretion noted. stroma shows desmoplasia and lymphomononuclear infiltrate. few atypical are seen at a solitary focus showing stroma infiltration,biopsy from right breast:few atypical cells suspicious of malignancysuggest repeat biopsy.
MR1709615,mass in left breast carcinoma breast.,biopsy from left breast.,received grey white to grey brown linear cores measures 1 1.2cm. entire tissue processed.,section show fibrofatty tissue with an infiltrate lesion arranged in cords and tubules. cells show pleomorphic hyperchromatic nuclei and moderate cytoplasm. mitotic figures discerned.,biopsy from left breast:infiltrating carcinoma nst grade ii.tubular formation 2nuclear pleomorphic 2mitotic figures 2 6 9
MR1709667,birads iv lesion in right breast.,biopsy from right breast.,received multiple grey white linear cores measures 0.5 0.8cm.entire tissue is processed.,section shows linear cores of breast parenchyma harboring an infiltrative lesion arranged astubules nests and linear cords. the cells have round to oval hyperchromatic pleomorphic nucleusand scanty to moderate cytoplasm. mitotic figures discerned.stroma shows desmoplasia and lymphomononulcear infiltrate.,biopsy from right breast:invasive carcinoma nst grade ii.mbr score is 6 9tubule formation 2nuclear pleomorphism 2mitotic figures(5 6 0hpf) 2 6 9
MR1709678,right breast lump under evaluation.,right breast lump right breast lumpectomy.,received lumpectomy specimen measures 6.5x6x3cm cut surface shows a grey white lesion measures 3x2x1.5cm. located at the following distances from the respective margins superior margin 2cminferior margin 1.5cmmedial margin 0.5cmlateral margin 0.1cmdeep margin 0.5cm.,section shows breast parenchyma with an infiltrating lesion arranged in nests and papillary pattern.the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominentnucleoli in few. mitotic figures are discerned. stroma shows desmoplasia with areas of hemorrhageand necrosis.medial margin of resection shows ductal carcinoma in situ.lateral margin of resection is involved by invasive carcinoma.all other margins of resection (superior inferior and deep )are free of tumor.,right breast lump right breast lumpectomy:invasive papillary carcinoma.ductal carcinoma in situ papillary and solid pattern are seen.lymphovascular and perineural invasion are not seen.medial margin of resection shows ductal carcinoma in situ.lateral margin of resection is involved by invasive carcinoma.all other margins of resection (superior inferior and deep )are free of tumor.
MR1709718,carcinoma left breast ill defined lesion in left breast.,biopsy from left breast lump.,received 5 linear core measuring 0.5 to 0.8cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in tubules and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. occasional mitotic figures are discerned. stroma shows desmoplasia with areas of hemorrhage.,left breast lump biopsy:invasive carcinoma nst grade itubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9
MR1709719,right lumpectomy statususg residual carcinoma.,right breast.,received multiple grey white linear cores measures 0.8 to 1.0cm.entire tissue is processed.,section show cores of fibrofatty tissue with a neoplastic lesion arranged in papillary and cribriform pattern. cells show mild to moderate pleomorphism with vesicular nuclei inconspicuous nucleoli and moderate cytoplasm. peritumoral and perivascular lymphocyticinfiltration seen.,right breast:suggestive of ductal carcinoma in situ papillary and cribriform patterninvasion could not be made out.suggest excision biopsy.
MR1709725,carcinoma left breast.,left breast.,received multiple grey white to grey yellow linear cores measures 0.5cm 1cm. entire tissue is processed.,section shows fibrofatty tissue with an infiltrative lesion arranged in cords and strands. cells show oval to elongated irregular hyperchromatic nuclei and moderate eosinophilic cytoplasm.stroma shows mild lymphocytic infiltrate.,left breast :invasive carcinoma with papillary features.
MR1709730,left breast lump possibility of carcinoma breast.,biopsy from left breast .,received five grey white to grey brown linear cores measures 0.5 0.8cm. entire tissue processed.,section shows linear cores of breast parenchyma exhibiting few foci of an infiltrative lesion arranged as tubules and cords. the cells have round to oval hyperchromatic nucleus dispersed chromatin and moderate pale to vacuolated cytoplasm. foci of ductal carcinoma in situ(papillary type) and usual ductal hyperpasia noted. focal areas show apocrine metaplasia. stroma is desmoplastic.,biopsy from left breast:suggestive of invasive carcinoma nst nuclear grade ii with ductal carcinoma in situ papillary type.
MR1709752,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white to grey brown linear cores measures 0.7x1.3cm.entiretissue is processed.,section shows tumor cells in nests cords and diffuse sheets. individual cells have hyperchromatic nucleiand moderate amount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+2 3).
MR1709761,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measures 0.8 to 1.0 cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,biopsy from right breast :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1709807,left breast lump carcinoma.,biopsy from left breast.,received multiple grey white to grey brown linear cores measures 0.8 1cm.entire tissue isprocessed.,section shows linear cores of breast parenchyma harboring an infiltrative lesion arranged ascords and nests. the cells have round to oval hyperchromatic pleomorphic nucleus and scantyto moderate cytoplasm. few dilated ducts with luminal secretions noted. stroma shows desmoplasia.,biopsy from left breast.invasive ductal carcinoma grade 2.mbr score is 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1709814,tiny papillary lesion in left breast.,biopsy of left breast lesion.,received multiple grey white to grey yellow linear cores measures 0.6 1cm.entire tissueis processed.,section shows linear cores of breast parenchyma harboring an infiltrative lesion arranged as sheets and papillary pattern. the cells are columnar to oval with hyperchromatic pleomorphic nucleus and moderate eosinophilic to vacuolated cytoplasm. few cells show vesicular nucleus and prominent nucleoli. stroma shows inflammatory infiltrate.,biopsy from left breast.invasive papillary carcinoma grade 2mbr score 7 9tubule formation 2nuclear pleomorphism 2mitosis 3 7 9
MR1709819,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received multiple grey white to grey yellow linear cores measures 0.8 1cm.entire tissue is processed.,section shows linear cores of breast parenchyma harboring an infiltrative lesion arranged as cords nests and tubules. the cells have round to oval hyperchromatic moderately pleomorphicnucleus and moderate cytoplasm. stroma shows desmoplasia.,biopsy from left breast:invasive ductal carcinoma grade 2.mbr score 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR1709823,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received multiple grey white to grey brown linear cores measures 1 to 1.2cm.entire tissue is processed.,section shows linear cores of fibrous tissue exhibiting an infiltrative lesion arranged as cords and nests.the cells have hyperchromatic moderately pleomorphic nucleus and scanty cytoplasm. stroma showsdesmoplasia and lymphomononuclear infiltrate.,biopsy from right breast:invasive ductal carcinoma grade 2.mbr score is 7 9tubule formation 3nuclear pleomorphism 2mitosis 2 7 9
MR1709897,carcinoma right breast.,right breast.,received in : formalin.procedure : modified radical mastectomy.laterality : right.total dimensions : medial to lateral : 14cm. superficial to deep : 4 cm. superior to inferior :13 cm.skin ellipse : 11x8cm.nipple : retracted.scar surgical defect : present around nipple areolar complex tumor : grossly fibrotic and grey brown areas seen in the inferior quadrant measures 0.5 x0.4x0.4 cm.margins of tumor : ill defined.deep margin : 1.5 cm.muscle : present measuring 3x2.5cm.adjacent breast : fibrofatty.axillary tail : 4.5x4x3.5cm.size of largest node : measures 3.2x2x1.5cm. cut surface is grey white,multiple sections from lumpectomy bed show extensive lymphocytic inflammatory cell infiltrate foamy macrophages multinucleated foreign body giant cells. small focus of dcis seen.no residual invasive tumor cells seen. section from deep margin and nipple are unremarkable. 10 21 lymph nodes from right axilla show metastatic deposits of tumor..perinodal spread seen.,10 21 lymph nodes isolated from right axillary dissection show metastatic deposits of tumor. perinodal spread seen. lumpectomy bed shows a focus of dcis.deep margin free of tumor.nipple free of tumor.
MR1709906,large right breast lump.,biopsy from right breast.,received4 grey white linear cores measures 0.8 to 1.4cm. entire tissue processed.,section shows linear cores of tissue harboring an infiltrative lesion arranged as sheets nests and cords. the cells have round to oval hyperchromatic moderately pleomorphic nucleus prominent nucleoli and moderate cytoplasm. mitotic figures are 10 11 10 hpf. extensive areas of necrosis noted. few multinucleated cells seen,biopsy from right breast: invasive carcinoma nst grade 3.modified bloom richardson score is 8 8tubule formation 3nuclear pleomorphic 2mitosis 3 8 9
MR1709931,left breast carcinomaoutside fnac duct carcinoma.,left breast lump biopsy.,received multiple grey white linear cores measures 0.6 0.8cm.entire tissue is processed.,section shows fibrocollagenous tissue harboring an infiltrating lesion arranged in cords and sheets.the cells are ovoid having moderate amount of cytoplasm hyperchromatic and prominent nucleoli.mitotic figures are discerned. stroma shows desmoplasia with lymphomononuclear infiltrates. areas of calcification hemorrhage and necrosis seen.,left breast lump biopsy:invasive carcinoma nst grade 2tubule formation 3nuclear pleomorphism 2mitotic figures 2 mbr score 7 9
MR1709967,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white grey yellow linear cores measures 1 1.2cm.entire tissue is processed.,linear cores of breast tissue harboring neoplasm arranged as islands and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. comedopattern ductal carcinoma in situ noted.,infiltrating ductal carcinoma biopsy from left breast.grade 2 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1709993,k c carcinoma right breast.,bilateral salpingoopherectomy.,received bilateral salpingoopherectomy larger ovary measures 3.5x2x0.5cm. cut surface cystic measures 1.5x1cm attached tube measures 2.5cm. cut surface show unremarkable. fimbrial end is identified paratubal cyst noted measures 1x1cm. smaller ovary measures 3x2x1.2cm. cut surface is unremarkable. attached tube measures 2.2cm. cut surface show unremarkable fimbrial end identified.,section from both ovaries shows ovarion parenchyma with interspersed thick blood vessels and cystic lesion lined by stratified lueteal cells with no atypia. stroma shows desmoplasia with areas of hemorrhage.paratubal cyst lined by cuboidal epithelium with no atypia no evidence of malignancy in the material submitted,bilateral salpingoopherectomy:both ovaries show luteal cysts.both tubes are unremarkable.no significant pathology noted.
MR1710003,left breast lump carcinoma.,biopsy of left breast lump.,received multiple grey white linear cores ranging in size from 0.5 2cm.entire tissue is processed.,linear cores of breast parenchyma harboring a neoplasm arranged as clusters and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is elastotic.,infiltrating ductal carcinoma biopsy from left breast.grade 2 mbr score is 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1710043,mass in left breast carcinoma breast.,biopsy from left breast.,received 4 grey white to grey brown linear cores altogether measures 0.9 to 1.3cm. entire tissue processed.,section shows linear core of fibrous tissue harboring an infiltrative lesion arranged as cords nests and sheets. the cells have round to oval hyperchromatic moderately pleomorphic nucleus and scanty cytoplasm. mitotic figures are 7 8 hpf. stroma shows desmoplasia.,biopsy from left breast:invasive carcinoma nst grade 2modified bloom richardson score is 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1710104,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received multiple grey brown to grey yellow linear cores measures 0.2 0.5cm.entire tissue is processed.,section shows linear cores of breast parenchyma over the cores showing an infiltrative lesion arrangedas cords and tubules. the cells have hyperchromatic moderately pleomorphic nucleus and scanty cytoplasm. occasional mitosis noted. stroma shows extensive desmoplasia.,biopsy from left breast:invasive carcinoma nst nuclear grade i.
MR1710111,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received multiple grey white to grey yellow linear cores measures 0.5 0.7cm. entire tissue isprocessed.,section shows linear cores cores of fibrous tissue harboring an infiltrative lesion arranged as nests tubulesand cords. the cells have round to oval hyperchromatic moderately pleomorphic nucleus and scanty cytoplasm. mitotic figures are 6 7 10hpf. intervening stroma shows inflammation.,biopsy from left breast:invasive carcinoma no special type grade 2.mbr score 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR1710117,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received multiple grey white to grey yellow linear cores measures 1 1.2 cm. entire tissueis processed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderateamount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1710129,right breast lump p o carcinoma breast.,biopsy from right breast.,received multiple grey white linear cores measures 0.5 1.2cm. entire tissue processed.,section shows linear cores of tissue exhibiting a lesion arranged as nests and sheets. the cells have round to oval hyperchromatic moderately pleomorphic nucleus and scanty cytoplasm. mitotic figures are 7 8 10hpf. intervening stroma shows extensive areas of necrosis and desmoplasia. ductal carcinoma in situ with comedonecrosis seen.,biopsy from right breast:invasive carcinoma nst grade 2.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9 dcis with comedonecrosis seen.
MR1710172,carcinoma right breast.,right breast right modified radical mastectomy.,received in : formalintime of receipt at lab : 4.30pm. procedure : mastectomy post nact laterality : right mrm.total dimensions : medial to lateral : 15cm. superficial to deep :4cm. superior to inferior : 14cm.skin ellipse : 14x8cm. nipple :unremarkable.scar surgical defect : not seen.tumour size : ill defined grey white cystic a mucinous areas measures 4x4x3cm. location of tumor : upper outer quadrant.margins of tumor : ill defined. deep margin : 1cm.muscle : present measures 4x3cm.adjacent breast : fibrofatty tissue. axillary tail : 6x4x2cm.total number of nodes : 10 size of largest node : 2x1.5x0.8cm cut surface fat infiltration.,tumor bed :invasive papillary carcinoma with mucinous carcinoma.maximum dimension of tumor 4cm.invasive carcinoma measures 2.2cm. ductal papillary carcinoma in situ is measures 1.8cm.,right breast right modified radical mastectomy :invasive papillary carcinoma with mucinous carcinoma. grade ii.modified br score is 7 9.tubule formation: 3nuclear pleomorphism: 2mitotic figures: 2tumor measures 4cm in greatest dimension and is located in the upper outer quadrant quadrant. ductal carcinoma in situ present with intra ductal papillary carcinoma in situ.lymphovascular invasion not present.perineural invasion not present.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: 10 lymph nodes show no metastatic deposits of tumor.(0 10)summary :right mrm papillary mucinous carcinoma with extensive areas of ductal carcinoma in situ grade ii.nodal metastases 10 nodes no deposits of tumor. (0 10)pathological stage : pt2n0.
MR1710176,breast lump for evaluation carcinoma breast.,biopsy from right breast lump trucut biopsy.,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplasm arranged in cores and nests. lesional cells are pleomorphic with round to oval hyperchromatic nucleus inconspicuous nucleoli and moderate to abundant amount of eosinophilic cytoplasm. surrounding stroma shows desmoplasia. mitosis is discerned.,biopsy from right breast lump trucut biopsy :invasive duct carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1710209,left breast lump p o carcinoma breast.,biopsy from left breast lump.,received multiple grey brown to grey yellow measures 0.6 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma with a cellular lesion arranged in sheets. the cells are round to ovoid having moderate amount of cytoplasm and centrally to peripherally placed hyperchromatic nucleus. stroma shows desmoplasia with lymphomononuclear infiltrates. areas of hemorrhage and necrosis are seen.,biopsy from left breast lump:the possibilities considered are 1) lobular carcinoma.2) plasma cell neoplasm.suggest ihc.
MR1710230,mass in right breast carcinoma breast.,biopsy from right breast mass.,received 3 greywhite to greyyellow linear cores measuring 0.3 to 0.7cm. entire tissue processed.,section shows linear cores of fibroadipose tissue harboring an infiltrative lesion arranged as nests sheets and cords. the cells have round to oval hyperchromatic moderately pleomorphic nucleus and scanty cytoplasm. mitotic figures discerned. stroma shows focal lympho mononuclear infiltrate.,biopsy from right breast mass:invasive carcinoma nst grade 2.mbr score is 7 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1710233,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received multiple grey white linear cores measures 1 1.3cm.entire tissue is processed.,section shows linear cores of tissue harboring an infiltrative lesion arranged as tubules nests andcords. the cells have round to oval hyperchromatic moderately pleomorphic nucleus prominent nucleoli and moderate cytoplasm. mitotic figures are 6 7 10hpf. stroma shows desmoplasia.,biopsy from right breast.invasive carcinoma no special type grade 2.mbr score is 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR1710235,right breast lump p o carcinoma breast.,biopsy from right breast lump.,received 4 grey white grey yellow linear cores measures 1 1.4cm. entire tissue processed.,section shows cores of breast parenchyma harboring a lesion arranged cords and singly dispersed cells. cells have round to oval hyperchromatic nuclei and moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. adjacent stroma shows desmoplasia hemorrhage and lymphocytic infiltration. brisk mitotic activity noted.,biopsy from right breast lump:invasive carcinoma nuclear grade 2.
MR1710299,carcinoma left breast post opliver sol metastatic.,biopsy from liver lesion.,received multiple grey white linear cores measures 1 1.2cm.entire tissue is processed.,section shows linear cores of tissue harboring an infiltrative lesion arranged as nests and cords.the cells are round to oval hyperchromatic moderately pleomorphic nucleus and scanty cytoplasm.stroma shows focal myxoid change and hyalinisation.,biopsy from liver lesion:metastatic carcinoma in a known case of carcinoma left breast.
MR1710329,carcinoma right breast post op recurrent.,biopsy from right breast lesion.,received multiple greywhite soft tissue bits altogether measuring 1.5x1x0.8cm. entire tissue processed.,section shows multiple fragments of tissue harboring an infiltrative lesion arranged as nests and sheets. the cells have round to oval hyperchromatic markedly pleomorphic nucleus and moderate cytoplasm. few interspersed large cells with vesicular nucleus and prominent nucleoli. intervening stroma shows areas of necrosis and sheets of foamy histiocytes.,biopsy from right breast lesion:invasive carcinoma nst grade 3.suggestive of recurrence in a known case of carcinoma right breast post op.mbr score is 8 9.tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1710381,mass in right breast carcinoma breast.,biopsy from right breast mass.,received multiple grey white grey yellow linear cores measures 1 1.2cm.entire tissue is processed.,section show linear cores of breast parenchyma harboring a lesion arranged in sheets. the cells have moderately pleomorphic round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma show fibrosis and few congested blood vessels seen. mitotic figures discerned.,biopsy from right breast mass:invasive carcinoma grade ii.tubule formation 3nuclear pleomorphism 2mitotic figures 2 mbr score 7 9
MR1710385,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received multiple grey white grey yellow linear cores measures 0.8 1.2cm.entire tissue isprocessed.,section shows cores of breast parenchyma harboring a lesion arranged in sheets nests cordspattern. cells exhibit moderate nuclear pleomorphism hyperchromatic to vesicularnuclei prominent nucleoli and moderate amount of cytoplasm. adjacent stroma shows desmoplasiaand dense lymphocytic infiltration. mitotic figures discerned. lymphovascular invasion seen.,right breast lump. biopsy:invasive carcinoma no special type grade 3.mbr score 8 9tubule formation 3nuclear pleomorphism 2mitotic figures 3 8 9 lymphovascular invasion seen
MR1710401,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received 4 grey white to grey yellow linear cores measures 02. to 1cm entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged as islands and sheets. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma shows lymphoplasmacytic inflammatory cell infiltrate.,biopsy from right breast:invasive ductal carcinoma grade 2 .modified bloom richardson score is 6 9.tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1710425,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.2 1cm.entire tissue is processed.,section shows cores of breast parenchyma harboring a lesion arranged in nests and cordsand singly scattered cells. cells have hyperchromatic nuclei and moderate amount of cytoplasm.other cores shows presence of pleomorphic cells in desmoplastic stroma. atypical mitotic figures discerned.,left breast lump biopsy:poorly differentiated malignancy.possibility of metaplastic carcinoma is considered.
MR1710454,left breast lump,biopsy from right breast.,received 6 grey white linear cores measures 1 1.2cm. entire tissue processed.,section shows linear cores of fibrous tissue harboring an infiltrative lesion arranged as linear cords and nests. the cells have round to oval hyperchromatic moderately pleomorphic nucleus and scanty cytoplasm. mitotic figures are 6 7 10hpf. stroma shows extensive desmoplasia.,biopsy from left breast:invasive carcinoma nst grade 2tubule formation 3nuclear pleomorphism 2mitosis 2 7 9
MR1710478,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 1 1.5cm.entire tissue is processed.,section show fibrocollagenous tissue with atypical cells in strands and scattered singles infiltrating the stroma. cells are pleomorphic with irregular hyperchromatic nuclei. stromashows lymphocytic infiltrate. marked areas of hyalinisation seen.,left breast lump:scattered atypical cells suspicious of malignancy.suggest repeat biopsy.
MR1710481,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received multiple grey white linear cores measures 0.6 1cm.,section shows breast parenchyma harboring a lesion arranged in nests and cords. cells are pleomorphicwith vesicular nuclei prominent nucleoli and moderate eosinophilic cytoplasm. mitotic figures discerned.large areas of ductal carcinoma in situ with comedonecrosis seen.,right breast lump:infiltrating carcinoma no special type grade iii with focus of papillary differentiation.mbr score 8 9tubule formation 3nuclear pleomorphism 2mitotic figures 3 8 9 ductal carcinoma in situ with comedonecrosis seen.
MR1710522,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received multiple grey white linear cores measures 0.4 1cm.entire tissue is processed.,section show linear cores of breast parenchyma harboring a lesion consisting of duct with neoplastic arranged in cribriform and solid pattern. the cells having round to oval hyperchromaticnuclei and moderate amount of cytoplasm. ducts have outer myoepithelial cell layer. stroma showfibrosis.,left breast lump core biopsy extensive ductal carcinoma in situ (intermediate to high grade) cribriform solid pattern.note:adjacent invasive focus needs to be excluded on larger tissue.
MR1710593,b) left breast lump possibility of carcinoma breast.,b) left breast lump biopsy.,b) received multiple grey white linear cores measures 0.8 1 cm. entire tissue is processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,b) left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6( 3+2+1).
MR1710632,a) right breast lump possibility of carcinoma breast.,a) biopsy from right breast lump.,a) received multiple grey white linear cores measures 0.8 1cm.entire tissue is processed.,section shows linear cores of tissue harboring an infiltrative lesion arranged as nests and lobules.the cells are oval with round hyperchromatic nucleus and moderate cytoplasm. few cells showplasmacytoid appearance. mitotic figures are 3 4 10 hpf. stroma shows hyalinization. areas ofhemorrhage noted.,a) biopsy from right breast lump:invasive carcinoma with papillary differentiation nuclear grade 1.
MR1710678,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.3 1cm.entire tissue is processed.,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets and nests.individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,biopsy from left breast lump:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1710683,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey yellow linear cores measures 1 1.2cm.entire tissue isprocessed.,section shows linear cores of fibroadipose tissue harboring an infiltrative lesion arranged asnests and sheets. the cells have round to oval hyperchromatic pleomorphic nucleus and moderate cytoplasm. few cells show cytoplasmic vacuolation. mitotic figures are 4 5 10hpf.,biopsy from right breast:invasive carcinoma no special type grade2.tubule formation 3nuclear pleomorphism 2mitotic figures 1 mbr score 6 9
MR1710687,left breast lumpectomy.,left breast lump.,received unoriented lumpectomy specimen measures 6x5.5x2cm outer surface irregular cutsurface show solid and a cystic cavity measures 5x2x1cm. distance from the nearest inkedmargin 0.3cm.slit like spaces noted.,sections from the lump show breast parenchyma with preserved lobular architecture few ductsshow cystic dilatation with intraluminal secretions. there is focal ductal hyperplasia. stromashows increased collagen and fibrosis. foci of periductal inflammation predominantly composed of neutrophils also noted. no evidence of in situ or invasion carcinoma noted.,left breast lump:features are suggestive of fibrocystic disease.
MR1710717,case of right breast carcinoma with left breast lump.,a) right breast modified radical mastectomy.b) left breast wide excision.,a) received in : formalin procedure : modified radical mastectomy laterality : righttotal dimensions : medial to lateral :22cm superficial to deep :7cm superior to inferior : 17cmskin ellipse :15x10.5cmnipple : normal scar surgical defect : scar seen in upper central quadrant. measures 2cm in length.tumor : single tumor size : 2x1.5x1cmlocation of tumor : upper central quadrantmargins of tumor : ill defined deep margin : 3cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail :7x6x3cmsize of largest node : 1.8x0.8x0.5cm cut surface grey white to grey brown.b) received lumpectomy specimen measures 6.0x5.5x1.5cmskin ellipse measures 2x1.5cmcut surface shows small grey white ill defined lesion measures 1x0.8x0.6cm.distance from margins:superior margin : 0.5cminferior margin :0.6cmmedial margin :2.5cmlateral margin :0.5cmdeep margin :2.5cm,b) section shows intraductal lesion with increased cellularity moderate atypia with vesicular nucleus eosinophilic cytoplasm tumor is surrounding by outer myoepithelial cells . in focal areas and invasion into the stroma present.,a)right post nact modified radical mastectomy:tumor bed:tumor bed shows invasive carcinoma with abundant eosinophilic cytoplasm with vesicular pyknotic nuclei. surrounding area of show fibrosis necrosis and lymphoplasmacytic infiltrationright modified radical mastectomy.residual invasive ductal carcinoma grade iimodified bloom richardson score is 6 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1tumor measures 2cm in greatest dimension and located in the central regionductal carcinoma in situ present solid type intermediate gradelymphovascular invasion not identified.perineural invasion not identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes 13lymph nodes metastasis 0 0 13b) suggestive of papillary neoplasm with papillary ductal carcinoma in situ with suspicious foci of invasionsuggest ihc for defintive opinionsummary:right post nact modified radical mastectomy residual invasive ductal carcinoma grade 2
MR1710749,liver mets in a known case of carcinoma breast.,biopsy from liver mass.,received multiple grey white linear cores measures1 to 1.5cm. entire tissue processed.,section shows linear cores of fibrous tissue harboring an infiltrating lesion arranged in cords and sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned stroma shows desmoplasia with areas of hemorrhage and necrosis.,biopsy from liver mass:metastatic carcinoma probably from breast.
MR1710790,mass in right breast carcinoma breast.,biopsy from right breast mass.,received multiple grey white linear cores measures 1 1.2cm. entire tissue is processed.,section shows breast parenchyma with an invasive neoplasm composed of cells arranged in tubularfashion with moderate pleomorphism and atypical pleomorphic nuclei. adjacent ductal carcinoma insitu component( solid and cribriform) also noted. modified br score is 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9 grade 2.,features are that of invasive ductal carcinoma no specific type grade 2.
MR1710798,follow up case of carcinoma right breast.multiple liver lesion metastases.,biopsy from liver lesion.,received 5 grey white linear core measures 1 to 1.5cm. entire tissue processed.,linear cores of liver parenchyma infiltrated by neoplasm arranged in trabecular and glandular pattern. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. mitotic figures are see.,invasive carcinoma. metastatic. suggest ihc.
MR1710801,carcinoma breast.,biopsy from right breast.,received multiple grey white to grey brown linear cores measures 0.3 to 0.8cm. entire tissue processed.,section shows cores of breast parenchyma with an infiltrative lesion arranged in diffuse sheets nests and cords cells are pleomorphic with vesicular nuclei prominent nucleoli and moderate eosinophilic cytoplasm. mitotic figures discerned. stroma shows marked desmoplastic reactive necrosis in fibrosis.,biopsy from right breast:infiltrating carcinoma with papillary features grade iii.modified bloom richardson score is 8 9.tubular formation 3nuclear pleomorphic 2mitotic figures 3 8 9 areas of necrosis seen.
MR1710820,mass in left breast carcinoma breast.,biopsy from left breast mass.,received 3 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section shows cores of breast parenchyma harboring a lesion arranged in tubular nests. cells exhibit pleomorphic vesicular nuclei prominent nucleoli and moderate eosinophilic to clear cytoplasm. stroma shows mild lymphocytic infiltrate.,left breast:infiltrating carcinoma nst grade iimodified bloom richardson score is 6 9.tubule formation :2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1710861,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.8 1.2cm.entire tissue is processed.,section show linear cores of breast parenchyma with an infiltrating lesion arranged in sheets having round to oval moderately pleomorphic nuclei and moderate amount of cytoplasm. bizarre forms and mitotic figures discerned. stroma is elastotic with scattered stromal cells.,left breast lump core biopsy invasive ductal carcinoma grade ii.mbr score 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1710869,left breast lump p o carcinoma breast.,left breast lump core biopsy.,received multiple grey white to grey yellow linear cores measures 1 to 1.2cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1710873,carcinoma left breast.,right supraclavicular lymph node core biopsy.,received 3 grey white linear cores measures 0.6 to 1cm. entire tissue processing.,section show linear cores of tissue showing large areas of necrosis and hyalinisation. vague granuloma formation and multinucleated giant cells noted.aggregates of foamy macrophages and lymphocytes noted.,right supraclavicular lymph node core biopsy:granulomatous lymphadenitis
MR1710907,carcinoma breast.,left breast lump core biopsy.,received multiple grey white linear cores measures 0.3 to 0.8cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in nests and cores. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1710924,right neck node in case of carcinoma right breast buccal mucosa post op post rt.,right neck node along with skin.,received single skin covered soft tissue bit measuring 1x1x0.5 cm cut surface shows grey white area measures 0.2 cm in diameter.,sections shows stratified epithelium with subepithelium shows inflammation infiltrates composed of lymphocytes neutrophils and eosinophils. admixed periappendageal lymphocyte infiltration seen.,right neck node along with skin : chronic non specific inflammation. treatment related changes seen.
MR1710939,right breast lump carcinoma breast.,biopsy from right breast.,received 5 grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section sows linear cores of tissue harboring an infiltrative lesion arranged as linear cords and sheets . the cells have round to oval hyperchromatic pleomorphic nucleus and scanty cytoplasm. mitosis 6 7 10hpf. areas of necrosis identified.,biopsy right breast:invasive carcinoma nst grade 2modified bloom richardson score is 7 9tubule formation 3nuclear pleomorphism 2mitosis 2 7 9 large areas of necrosis noted.
MR1710960,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 4 grey white to grey brown linear cores measures 0.7 to 1cm. entire tissue processed.,sectionm shows linear cores of tissue harboring an infiltrative lesion arranged as nests and sheets. the cells have round to oval hyperchromatic nucleus with moderate pleomorphism few with prominent nucleoli with indistinct cell border and moderate to abundant granular cytoplasm. mitotic figures are 3 4 10hpf. stroma shows desmoplasia and inflammation. areas of necrosis noted..,biopsy left breast:invasive carcinoma nst grade 2 with focal areas showing apocrine featuresmodified bloom richardson score is 6 9tubule formation 3nuclear pleomorphism 2mitosis 1 6 9 areas of necrosis seen.
MR1710973,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 5 grey white to linear cores measures 0.3 to 1cm. entire tissue processed.,section shows multiple cores of breast tissue with an infiltrating neoplasm composed of cells in nests and glandular pattern the cells show moderate atypia with pleomorphic hyperchromatic nuclei.one of the cores shows dense hyalinised areas,biopsy from left breast lump:invasive carcinomamodified bloom richardson score is 6 9 grade 2tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1710984,right breast lump biradsiv b,biopsy from right breast.,received 4 grey white to grey brown linear cores measures 0.5 to 1cm. entire tissue processed.,section section linear cores of breast tissue harboring a neoplasm arranged as clusters and tubules . the neoplastic cells are round to polygonal have vesicular nucleus conspicuous nucleoli and moderate cytoplasm. the intervening stroma is elastotic ..,biopsy from right breast:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9tubule formation :3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1711086,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received 5 linear cores of soft tissue bits measures 0.2 to 0.7cm. entire tissue processed.,section shows cores of breast parenchyma with an infiltrative lesion arranged in papillae with fibrovascular cores and in nests cells show ovoid vesicular nuclei and abundant eosinophilic cytoplasm. also seen cytic glanular and foamy histiocytes.,biopsy from right breast lump:invasive carcinoma with focal papillary features nuclear grade ii.
MR1711088,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores soft tissue bits each measures 0.5 to 1.0cm. entire tissue processed.,section shows breast parenchyma with an infiltrative lesion arranged in glandular and tubular pattern cells show vesicular nuclei inconspicuous nucleoli and moderate eosinophilic cytoplasm. mitotic figures discerned . ductal carcinoma in situ with comedo necrosis seen. stroma shows mild lymphocytic infiltration.,biopsy from right breast:infiltrating carcinoma nuclear grade iimodified bloom richardson score 6 9.tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9 ductal carcinoma in situ with comedo necrosis seen.
MR1711097,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received 4 grey white to grey brown and mucoid linear cores measures 0.6 0.8cm. entire tissue processed.,section shows tumor cell in nests and sheets lying in pools of mucin. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy :invasive carcinoma with mucinous features grade 2. modified bloom richardson score is 6(3+2+1)
MR1711145,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received multiple grey white linear cores measures 1 1.5cm.entire tissue is processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets and nests individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1711164,known case of carcinoma left breastleft chest wall lesion possibility of recurrence.,left chest wall lesion biopsy.,received multiple grey white to grey brown linear cores measures 1 1.2cm.entire tissue is processed.,sections show linear tissue cores showing sheets and glandular arrangement of neoplastic cells showing moderate amount of nuclear pleomorphism hyperchromatic and eosinophilic cytoplasm.these are surrounded by fibrocollagenous connective tissue.,known case of carcinoma left breastleft chest wall lesion biopsy.:invasive carcinoma recurrence.modified bloom richardson score 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9 grade 2.
MR1711175,ductectasia with lump left breast.,breast lump.,received unoriented unmarked lumpectomy specimen measures 7.5x7x3cm serial sectioningshows ill defined grey white granular areas altogether measures 5x3x2.4cm.distance from the nearest inked margin 0.1cm.,multiple sections show extensive ducts show ductal carcinoma in situ with solid and cribriformpatterns and occasional ducts show comedonecrosis. in focal areas suspicious of micro invasionpresent. resected margin close margin 0.1cm free from the tumor.,breast lump:extensive areas of ductal carcinoma in situsolid cribriform and occasional ducts with comedonecrosis.suspicious of microinvasionadvised ihc markers myoepithelial markers.
MR1711193,liver lesion metastases,biopsy from liver lesion.,received fragmented grey white to grey brown linear cores measures 0.8x1.2cm. entire tissue processed.,section shows cores of liver parenchyma with a lesion arranged in sheets and nests. the cells have round to oval hyperchromatic nuclei and moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. frequent mitotic figures (2 3 hpf) noted.,biopsy from liver lesion:metastatic carcinomatous deposits in a known case of carcinoma breast.
MR1711195,right breast lump mastitis carcinoma breastbirads iv.,biopsy from right breast lump.,received multiple grey white to grey yellow linear cores measures 0.6 1cm. entire tissue is processed.,section shows linear cores of breast parenchyma harboring a lesion arranged in sheets tufts and tubuleslesional cells have round to oval hyperchromatic nucleus with inconspicuous nucleus and moderateamount of eosinophilic cytoplasm epithelial ductal hyperplasia noted with myoepithelial lining. backgroundshows dense inflammation and necrosis.,right breast lump core biopsy :features are suggestive of atypical ductal hyperplasia in a background of inflammation.no definite evidence of invasive malignancy is seen.suggest excision of lump for further confirmation.
MR1711238,left breast lump.,a) left breast conserving surgery.b)left axillary nodes.,received a skin covered fibrofatty tissue measures 6.5x5x2cm. skin ellipse measures 6x1.8cm. surface shows a linear scar measures 2cm. cut surface shows grey white ill defined firm areas measuring 1x1x0.6cm. underlying the scar grey yellow tiny nodules noted measuring 0.7x0.6cm. distance from margins :superior : 0.9cm.inferior : 2cm.medial : 3.5cm.lateral : 2cm.deep : 2cm.received one fibrofatty tissue measures 5x3x2cm. largest lymph node measures 2x1.5x0.8cm. cut surface fatty infiltration.p e,lumpectomy wide excision post lumpectomy and nact :tumor bed :small focus of residual tumor present measures 1x1cm with invasive ductal carcinoma.modified br score 5 9 tubular formation : 2nuclear pleomorphism : 1mitotic figures : 2 5 9 nuclear grade : ilymphovascular invasion not present.perineural invasion not identified.ductal carcinoma in situ not present.all resected margins are free of tumor.axillary lymph nodes : 12 nodes no deposits of tumor.,residual viable tumor present measures 1x1cm with invasive ductal carcinoma.nuclear grade i.ductal carcinoma in situ not present.lymphovascular invasion not present.all resected margins free of tumor.axillary lymphnodes 12 nodes no deposits of tumor.pathological grade :pt1n0.
MR1711266,left breast lump.,biopsy from left breast lump.,received multiple grey white linear fragment measures 0.8 1cm.entire tissue is processed.,section show cores of breast tissue with an infiltrating neoplasm predominantly composed of cells in sheets and tubules with a desmoplastic stroma. the cells are highly ploemorphic have abundantto moderate eosinophilic granular cytoplasm pleomorphic hyperchromatic nucleoli few show prominent nucleoli. mbr score 7tubule formation 2nuclear pleomorphism 3mitotic figures 2 7 9,invasive carcinoma with apocrine features mbr score 7 grade ii..
MR1711273,right breast lump.,biopsy of right breast lump.,received multiple grey white to grey brown linear cores measures 1 1.2cm.entire tissue is processed.,section show linear cores of tissue harboring a lesion arranged in tubules and nests. the cellshave round to oval dark nuclei and inconspicuous nucleoli and moderate amount. stroma show sclerosis.,right breast lump:invasive ductal carcinoma grade i.mbr score 5 9tubule formation 2nuclear pleomorphism 2mitotic figures 1 5 9
MR1711316,known case of carcinoma testisright iliac node possibility of metastatic.,iliac node biopsy.,received multiple grey white to grey yellow linear cores measures 0.6 0.8cm.entire tissue is processed.,section shows cores of breast tissue with a lesion arranged in diffuse sheets. individual cells havehyperchromatic nuclei and moderate amount of cytoplasm. adjacent stroma shows lymphoplasmacyticinfiltration and areas of necrosis. crush artefacts noted.,iliac node biopsy:small focus of atypical cells.possibility of metastatic carcinoma in a known case of carcinoma testis.
MR1711341,carcinoma right breast.,right breast wedge biopsy.,received multiple grey white to grey brown soft tissue bits measures 1 x 0.8 x 0.7 cm. entire tissue processed .,section show stratified squamous epithelium with a infiltrating neoplasm arranged in nests and sheets. the cells forms the lesion are round to oval vesicular nuclei with prominent nucleoli. areas of necrosis. mitosis 5 6 10hpf.,right breast wedge biopsy :positive for malignancy.suggestive of recurrent carcinoma in a known and treated case of carcinoma breast.
MR1711385,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received multiple grey white to grey brown linear cores measures 0.6 1.2 cm. entire tissue is processed.,section shows tumor cells in diffuse sheets and cords. individual cells have hyperchromatic nucleiand moderate amount of cytoplasm.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1711416,left breast intraclavicular lesion birads ivc.,left breast core biopsy.,received multiple grey white to grey brown linear cores measures 1 1.2 cm. entire tissue is processed.,section shows tumor cells in nests cords and tubules. individual cells have hyperchromatic nucleiand moderate amount of cytoplasm.,left breast core biopsy :invasive ductal carcinoma grade 2. modified blood richardson score is 6(3+2+1).
MR1711463,birads 4 c lesion in left breast.,biopsy from left breast lesion.,received multiple grey white to grey yellow linear cores measures 1 1.2cm.entire tissue is processed.,sections from the breast biopsy show multiple cores of breast tissue with an infiltrating neoplasmin tubules. the cells have moderate cytoplasm and show moderate nuclear pleomorphism and hyperchromatism.tubule formation 2nuclear pleomorphism 2mitotic figures 3 7 9 mbr score 7adjacent ductal carcinoma in situ also seen solid type.,features are suggestive of invasive carcinoma ductal type(nos) grade ii.
MR1711504,mass in left breast carcinoma breast.,biopsy from left breast mass.,received multiple grey white linear cores measures 1 1.2cm.entire tissue is processed.,section shows cores of breast parenchyma with a lesion arranged in tubules and nests. cellshave hyperchromatic nuclei and moderate cytoplasm. adjacent stroma shows ductal proliferationand hyperplasia.,left breast mass biopsy:invasive ductal carcinoma grade 2mbr score 5tubule formation 2nuclear pleomorphism 2 mitotic figures 1 5 9
MR1711540,mass in right breast carcinoma breast.,biopsy from right breast.,received multiple grey white to grey brown linear cores measures 1 1.2cm.entire tissue is processed.,section shows breast parenchyma harboring a neoplastic lesion arranged in cords trabeculae sheets and tubules. the cells are moderately pleomorphic with round to oval hyperchromatic nuclei and moderatecytoplasm. mitotic figures are seen. areas of fibrosis noted. intervening stroma show lymphocytic infiltrate.,biopsy from right breast:suggestive of invasive ductal carcinoma grade ii.modified bloom richardson scoretubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1711570,left breast lump carcinoma breast.,left breast mass biopsy.,received multiple grey white to grey brown linear cores measures 1.2 1.4cm.,section from breast parenchyma show a neoplastic lesion arranged in cords trabeculae and sheets the cells have round to oval hyperchromatic to vesicular nuclei with few showing prominentnucleoli and moderate cytoplasm. areas of hyalinisation and necrosis seen. mitosis are seen.,left breast mass biopsy:invasive ductal carcinoma grade ii.areas of necrosis seen.modified bloom richardsontubule formation 3nuclear pleomorphism 3mitotic figures 1 7 9
MR1711582,left breast mass carcinoma breast.,biopsy from left breast mass.,received multiple grey white to grey brown linear cores measures 1 1.2cm.entire tissue is processed.,sections show cores of breast tissue with an infiltrating neoplasm predominantly in tubular and nestedpattern. the cells show moderate cellular atypia with nuclear pleomorphism and hyperchromatism. mitosis is increased.nollingham score tubule formation 2nuclear pleomorphism 2mitotic figures 3 7 9,features are suggestive of invasive carcinoma ductal type (nos) grade iimbr score 7.
MR1711619,right breast carcinoma.,right breast lump.,received a skin covered fibrofatty tissue measures 4.5x4x2.5cm on serial section identifieda well circumscribed whorled grey white firm lesion measures 1.5x1x1cm. distance from deep margin 0.6cm.distance from skin 2cm.,multiple sections show ducts and stroma. ducts are lined with cuboidal epithelial cells and arecompressed lined with outer myoepithelial cells. the stroma shows spindle cells with myxomatousareas. there is no evidence of malignancy.,breast lump:consistent with fibro adenoma.
MR1711631,right breast carcinoma breast.,biopsy from right breast mass.,received multiple grey white to grey yellow linear cores measures 1 1.2cm.entire tissue is processed.,sections from the biopsy show cores of breast tissue with an invasive neoplasm predominantlyin glands tubules and nests. the cells show moderate cellular atypia with moderatelypleomorphic nuclei showing hyperchromatism. the stroma appears desmoplastic. the tumorinvades the adipose tissue.nollingham score tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9 nuclear grade ii.,features are suggestive of invasive carcinoma ductal type (nos) grade iimbr score 6.
MR1711633,right breast lump carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey brown linear cores measures 1 1.2cm.entire tissue is processed.,sections show cores of breast tissue with glands and ducts showing extensive insitu carcinomawith focal apocrine and clear cell changes. few ducts show flat epithelial atypia. there are few foci showingdysplastic glands without myoepithelial layer.,extensive ductal carcinoma with foci suspicious for invasion.a repeat biopsy is suggested to rule out invasive malignancy.
MR1711635,right breast mass carcinoma breast.,right breast mass biopsy.,received multiple grey white to grey brown linear cores measures 1 1.2cm.entire tissue is processed.,section shows cores of breast parenchyma harboring a lesion arranged in sheets nests andcords. cells have round to oval and bizarre hyperchromatic nuclei and moderate amount of cytoplasm. stromal desmoplasia and lymphocytic infiltration noted.,right breast mass biopsy:invasive ductal carcinoma grade 3.mbr score 8 9tubule formation 3nuclear pleomorphism 3mitotic figures 2 8 9
MR1711646,known case of carcinoma right breast (post mastectomy status).right chest wall lesion possibility of deposit.,biopsy from right chest wall lesion.,received multiple grey white to grey brown linear cores measures 1 1.2cm.,section shows linear cores of biopsy showing cords trabeculae and occasional glandular structurescomposed of cells showing increased nucleo cytoplasmic ratio nuclear hyperchromasia pleomorphism and variable amount of pale eosinophilic cytoplasm. abundant fibrocollagenous stroma with focal myxoid change is seen. desmoplasia is noted.mbr score is 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9,biopsy from right chest wall lesion.:deposits of invasive carcinoma in a known case of carcinoma breast.
MR1711651,case of right breast lump.,right breast lump right sonolocalised excision biopsy.,received lumpectomy specimen measures 4 x 3.5 x 3 cm. skin ellipse measures 2.5 x 0.5 cm. section shows a grey white illdefined lesion with granular areas measures 3 x 2.5 x 2.3 cm.distance from margins :superior : 0.5cm.inferior : 0.5cm.medial : 0.4cm.lateral : lt 0.1cm.deep : 0.8cm.representative sections are submitted.,section studied shows breast parenchyma showing a cellular lesion located intraductally. the ducts show lesional cells arranged in solid sheets cribriform pattern and in few ducts papillary arrangement of cells is seen. the lesional cells have moderate amount of eosinophilic cytoplasm round to oval pleomorphic nuclei and prominent nucleoli. few ducts show comedonecrosis pattern. few ducts show lesion arranged in papillary arrangement with lesional cells arranged around fibrovascular core. occasional mitoses are seen. adjacent breast shows fibrosis. lymphovascular invasion is not seen.,right breast lump right sonolocalised excision biopsy :shows ductal carcinoma in situ of solid comedo and cribriform pattern with intermediate nuclear grade. size of the dcis measures 3 cm in greatest dimension. adjacent breast shows features of intraductal papilloma and adenosis. superior medial lateral and deep margins of resection shows ductal carcinoma in situ. inferior margin of resection is free of tumor.suggest to do ihc to rule out invasive component.
MR1711671,carcinoma breast right.,a)right axilla sentinel node biopsy.b) wide excision of right breast lump.c) revised inferior margin inked surface away from the tumor,a) received single fibrofatty tissue measures 3.5x1.5x0.8cm. isolated 2 lymph nodes one with dye:largest lymph nodes measures 2x1x0.8cmcut surface grey white( node with dye measures 1.5x0.5x0.4cm) entire tissue processed.b) received lumpetomy specimen measures 6x5x3.4cm.skin ellipse measures 2.5x0.5cm.cut surface shows grey white lesion measures 2.5x1.5x1cm. c) received single fibrofatty tissue meausres 4.5x3x1.5cm with one surface inkeddistance from marginsuperior :1.2cminferior : 0.9cm.medial : 0.9cmlateral : 1cmdeep : 0.5cm.,a) isolated 2 lymph nodes show no metastatic tumor deposits.b) section show breast parenchyma harboring an infiltrative lesion arranged as tubules nests sheets and cords. the cells have round to oval hyperchromatic nucleus with moderate atypia prominent nucleoli and moderate to abundant cytoplasm. ductal carcinoma in situ present. lymphovascular invasion not identified perineural invasion not identified.inferior margin shows fibroadenosis. other resected margins are unremarkable.overlying skin is unremarkable.c) revised inferior margin shows adenosis.,a) right sentinel lymph node:two lymph nodes no deposits of tumor (0 2).b) wide excision right breast lump:invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9.tubule formation 2nuclear pleomorphism 2mitosis 2 6 9 tumor measures 2.5cm in greatest dimension solid ductal carcinoma in situ present. lymphovascular invasion not identified.perineural invasion not identified..inferior margin shows fibroadenosis.superior medial lateral and deep resected margins are free of tumor.overlying skin is unremarkable.c) revised inferior margins shows fibroadenosis free of tumor.
MR1711672,lump in right breast.,right breast right modified radical mastectomy ( post chemo).,received in : formalinprocedure : mastectomy laterality : right.total dimensions : medial to lateral : 19cm. superficial to deep : 5cm. superior to inferior : 17cm.skin ellipse : 11x7cm. nipple :retractedscar surgical defect : not seen.tumour size : 1.5 x 1.5 x 1.2 cm. location of tumor : upper inner quadrant. margins of tumor : infiltrative. deep margin : 1.5cm.muscle : absent adjacent breast : fibrofatty axillary tail : 5 x 3 x 1.5 cm.size of largest node :1.5 x 1 x 0.8 cm cut surface grey white.,section shows residual tumor cells in nested and tubular pattern. individual cells have hyperchromatic cells and moderate amount of cytoplasm. lymphovascular invasion is seen. perineural invasion is not seen.,right breast right modified radical mastectomy(post chemo) :residual invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). tumor measures 1.5 cm in greatest dimension and is located in the upper inner quadrant. ductal carcinoma in situ is not seen. lymphovascular invasion is seen. perineural invasion is not seen. posterior resection margin is free of tumor. nipple and areola is free of tumor.lymph nodes: two out of fifteen lymph nodes show metastatic tumor deposits with extranodal extension(2 15). size of the larger tumor deposit measures 0.4 cm in greatest dimension.pathological stage : ypt1cn1a
MR1711699,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white to grey brown linear fragments measures 0.3 0.7cm.entire tissue is processed.,section shows linear cores of fibroconnective tissue harboring an infiltrating lesion arranged in sheets and vague tubules. the cells are ovoid having moderate amount of cytoplasm hyperchromatic pleomorphic nucleus and prominent nucleoli in few. mitotic figures arediscerned. stroma shows desmoplasia with lymphomononuclear infiltrates. areas of hemorrhage and necrosis seen.,biopsy from left breast lump:invasive carcinoma nst grade 3.tubule formation 2nuclear pleomorphism 3mitotic activity 3 8 9
MR1711712,carcinoma left breast t4b.,incision biopsy left breast.,received multiple grey white to grey brown soft tissue bits altogether measures 1x0.8x0.3cm.entire tissue is processed.,section shows skin with epidermis displaying orthokeratotic hyperkeratosis dermis shows a cellular lesionarranged in nests and lobules separated by thin fibrous septae. cells exhibit moderate nuclear pleomorphism with vesicular nuclei prominent nucleoli and abundant eosinophilic cytoplasm. peritumorallymphocytic infiltration seen.pagetoid spread in the epidermis noted.,incision biopsy left breast:invasive carcinoma nst grade 2 (3+3+1) 7 9tubule formation 3nuclear pleomorphism 3mitotic figures 1 7 9 pagetoid spread to the epidermis noted.
MR1711732,right breast lump carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey brown fragmented cores measures 0.3 to 0.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma with areas of fibrosis.,fibrotic cords.suggest repeat biopsy to confirm malignancy.
MR1711745,right breast lump birads v lesion.,biopsy from right breast.,received multiple grey white to grey brown linear cores measures 1.2 1.4cm.entire tissue is processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as tubules and clusters. the neoplastic cells are cuboidal have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is fibrous.,invasive ductal carcinoma biopsy from stomach grade 1tubule formation 2nuclear pleomorphism 2mitotic figures 1 5 9
MR1711750,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received multiple grey white to grey brown linear cores measures 1 1.2cm.entire tissue is processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as cords clusters and nests.the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nucleiand moderate cytoplasm. the intervening stroma is fibrous.,invasive ductal carcinoma right breast.grade 2tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1711801,known case of carcinoma breast multiple bone metastasis.,right iliac bone ct guided biopsy.,received 2 bone fragment measures 0.8 to 1cm. entire tissue processed.,section shows lameller bone with intertrabecular spaces marrow spaces are replaced by dense fibrosis tissue containing atypical cells. these cells are arranged in cords tubules and small clusters having round to oval hyperchromatic nucleus with moderate amount of cytoplasm.,right iliac bone ct guided biopsy:features are suggestive of metastatic carcinoma in a known case of carcinoma breast.
MR1711819,left breast mass carcinoma breast.,biopsy from left breast mass.,received multiple grey white to grey brown linear cores measures 1.2 1.4cm.entire tissue is processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords clusters and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromaticnuclei and moderate cytoplasm. areas of necrosis seen.,invasive ductal carcinoma biopsy from left breast.grade 2 tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9 report originally issued by dr daphne fonseca and dr ravindranath tagore amendment done on 16 8 17 carried out by dr sudha laterality reads as right breast request generated and amendment endorsed by dr pradeep radiologistthis report supersedes the earlier report amended report : invasive ductal carcinoma biopsy from right breast.grade 2 tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1711841,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received multiple grey white to grey brown linear cores measures 0.8 1cm.,section shows linear cores of fibroadipose tissue harboring an infiltrative lesion arranged astubules nests trabeculae and focal cribriform pattern. the cells have round to oval hyperchromatic pleomorphic nucleus and scanty to moderate cytoplasm. stroma shows desmoplasia.,biopsy from right breast.:invasive carcinoma nst grade i.mbr score is 5 9tubule formation 2nuclear pleomorphism 2mitotic figures 1 5 9
MR1711863,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white to grey brown linear cores measures 1.2 1.4cm.entire tissue isprocessed.,section shows cores of fibrous tissue with an infiltrative lesion arranged in cords and strands. cells show pleomorphic vesicular nuclei prominent nucleoli and abundant eosinophiliccytoplasm. mitotic figures discerned. stroma shows mild lymphocytic response.,left breast lump:invasive carcinoma with papillary features nuclear grade 2.
MR1711864,left breast mass carcinoma breast,biopsy from left breast.,received 3 grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section shows linear cores of fibrous tissue harboring an infiltrative lesion arranged as tubules nests and cords. the cells have round to oval hyperchromatic pleomorphic nucleus and moderate cytoplasm. few cells show cytoplasmic vacuolation. intervening stroma shows focal lymphomononuclear infiltrate. mitotic figures are 6 7 10hpf.,biopsy left breast:invasive carcinoma nst grade iimodified bloom richardson score is 6 9.tubule formation : 2nuclear pleomorphism : 2mitosis : 2 6 9
MR1711871,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received 5 grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section shows linear cores of fibrous tissue harboring an infiltrative lesion arranged as linear cores and nests. the cells have round to oval hyperchromatic pleomorphic nucleus and moderate eosinophilic to vacuolated cytoplasm. stroma shows desmoplasia. few cells show intracytoplasmic lumina.,biopsy from left breast:invasive carcinoma grade ii.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitosis : 2 7
MR1711904,a) right breast lump possibility of carcinoma breast.b) left breast lump possibility of carcinoma breast.,a) biopsy from right breast.b) biopsy from left breast.,a) received multiple grey white to grey brown linear cores measures 1 1.2cmb) received multiple grey white to grey brown linear core measures 1.2 1.4cm.,a) section shows cores of tissue with diffuse infiltration of atypical small cells with hyperchromaticnuclei and scant cytoplasm. interspersed are many congested blood vessels. crush artefacts noted.b) section shows cores of fibrous tissue infiltrated by diffuse sheets of small cells with dark nuclei and scant cytoplasm. interspersed are thin walled congested blood vessels. crush artefacts noted.,a) biopsy from right breast:malignant lesionthe possibility of hematolymphoid malignancy is consideredsuggest ihc.b) biopsy from left breast:malignant lesion. the possibility of hematolymphoid malignancy(lymphoid leukemia).suggest ihc.
MR1711933,carcinoma right breast.,biopsy from right breast.,received multiple grey white to grey brown soft tissue bits measures 1.5x1x0.5cm. entire tissue processed.,sections show fragmented tissue lets showing sheets and nests of malignant epithelial cells showing increased nuclei cytoplasm ratio hyperchromatic pleomorphic nuclei and abundant pale eosinophilic cytoplasm. there is abundant necroinflammatory infiltrate areas of necrosis and hemorrhage.,biopsy from right breast:invasive ductal carcinoma grade iimodified bloom richardson score is 6 9.tubular formation 3mitotic activity 1 nuclear pleomorphic 2 6 9 large areas of necrosis seen.
MR1711941,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white to grey brown linear cores measures 1 1.2cm.entire tissue is processed.,section shows cores of breast parenchyma with an infiltrative lesion arranged in cords nests and sheets. cellsare pleomorphic with vesicular nuclei prominent nucleoli and moderate eosinophilic cytoplasm. mitoticfigures discerned. stroma shows desmoplasia necrosis and hemorrhage.,biopsy from left breast lump:invasive carcinoma nst grade iii.mbr score 8 9tubule formation 3nuclear pleomorphism 2mitotic figures 3 8 9
MR1711945,mass in right breast carcinoma breast.,biopsy from right breast.,received 3 grey white to grey brown linear cores measures 0.8 to 1.0cm. entire tissue processed.,section shows cores of breast parenchyma with an infiltrative lesion arranged in glandular pattern. cells show ovoid hyperchromatic nuclei and moderate eosinophilic cytoplasm. stroma shows mild lymphocytic infiltrate.,right breast:invasive carcinoma nstnuclear grade ii.
MR1711972,left breast lump possibility of carcinoma.,left breast lump.,received 5 grey white to grey brown linear cores mesures 1 to 1.2cm. entire tissue processed.,section shows breast parenchyma with an infiltrative lesion arranged in cords.cells show hyperchromatic eccentrically placed nuclei and moderate eosinophilic cytoplasm.,biopsy from left breast lump:invasive carcinoma with lobular features nuclear grade 1
MR1711979,left breast lump. carcinoma breast.,biopsy from left breast lump.,received 4 linear grey white to grey brown soft tissue bits each measures 1.2 to 1.4cm in length. entire tissue processed.,section shows nests trabeculae and cords of neoplastic epithelial cells showing increased nucleo cytoplasmic ratio pleomorphic hyperchromatic nuclei and variable amount of clear to pale eosinophilic cytoplasm. these are surrounded by dense fibrocollagenous connective tissue.,biopsy from left breast lump:invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9.tubular formation 3 nuclear pleomorphism 2mitotic figures 2 7 9
MR1711990,left breast lump birads 4c lesion,biopsy from left breast lump.,received multiple grey white to grey brown linear cores measures 1 1.2cm.entire tissue isprocessed.,section shows cores of breast parenchyma with an infiltrative lesion arranged in cords and tubules.cells are moderately pleomorphic with vesicular nuclei prominent nucleoli and moderate eosinophiliccytoplasm. mitotic figures discerned. ductal carcinoma in situ with comedonecrosis seen. stroma shows lymphocytic infiltration and hemorrhage.,biopsy from left breast lump:invasive carcinoma nst grade ii.mbr score 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9 ductal carcinoma in situ with comedonecrosis seen.
MR1712019,a)carcinoma right breastright axillary node metastatic.,a) biopsy from right axillary node.,a) received multiple grey white to grey yellow linear cores measures 1 1.2cm.entire tissue is processed.,a) section shows multiple linear cores of fibrocollagenous tissue harboring a neoplasm arrangedin cords and nests and sheets. lesional cells highly pleomorphic round to irregular hyperchromatic nucleus some showing prominent nucleoli with abundant eosinophilic cytoplasm.,a) biopsy from right axillary node features are suggestive of metastatic carcinoma.
MR1712057,carcinoma right breast t4b n3,right breast incision biopsy.,received 4 grey white to grey brown soft tissue bits measures 1.5x1x0.3cm. entire tissue processed.,section shows breast parenchyma with an infiltrative lesion arranged in cords and islands. cells exhibit mild to moderate nuclear pleomorphism with vesicular nuclei prominent nucleoli and moderate eosinophilic cytoplasm. stroma shows lymphocytic infiltration thickened blood vessels and necrosis.,right breast incision biopsy:invasive carcinoma nst nuclear grade2areas of necrosis seen.
MR1712061,right breast lump possibility of carcinoma breast,biopsy from right breast lump.,received multiple grey white to grey brown linear cores measures 1 1.4cm.entire tissue is processed.,sections show fragmented tissue cores showing nests sheets fibroglandular structures trabeculae and cords of neoplastic epithelial cells showing increased nucleo cytoplasmic ratio hyperchromatic vesicular nuclei with scant cytoplasm. there is dense fibrocollagenous connective tissue along with abundantlymphoplasmacytic inflammation.,biopsy from right breast lump:invasive ductal adenocarcinoma grade 2.modified bloom richardson score 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1712109,left breast carcinoma.,left breast mass core biopsy.,received multiple grey white to grey brown linear cores measures 0.8 to 1 cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. pools of extracellular mucin are seen. individual tumor cells have hyperchromatic nuclei and moderate amount of cytoplasm. few signet ring cells are also seen.,left breast mass core biopsy :invasive carcinoma with mucinous features grade 2. modified bloom richardson score is 6(3+2+1).
MR1712129,right breast lump.,right breast lump core biopsy.,received multiple grey white to grey brown linear cores measures 1.2 to 1.4 cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests and fused glandular pattern. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1712140,right breast lump possibility of carcinoma breast.,right breast lump biopsy.,received 5 grey white to grey brown linear cores measures 0.8 to 1.2 cm. entire tissue processed.,section shows breast parenchyma harboring a lesion arranged in nests cords and tubules. cells have hyperchromatic moderately pleomorphic nuclei and moderate and moderate amount of cytoplasm. stroma shows fibrosis noted. mitotic figures discerned.,right breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score 6(3+2+1).
MR1712155,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white to grey yellow linear cores measures 1 1.4cm.entire tissue isprocessed.,section shows cores of fibrous tissue with an infiltrative lesion arranged in cords and tubules. cells exhibit moderately pleomorphic hyperchromatic nuclei and moderate eosinophilic cytoplasm.mitotic figures discerned. ductal carcinoma in situ with comedonecrosis seen.,biopsy from left breast lump:infiltrating carcinoma nst grade ii.mbr score is 7 9tubule formation 3nuclear pleomorphism 2 mitotic figures 2 7 9 ductal carcinoma in situ with comedonecrosis seen.
MR1712225,left breast mass carcinoma breast.,biopsy from left breast.,received multiple grey white to grey brown linear cores measures 1.2 1.4cm.entire tissue isprocessed.,section shows linear cores of breast parenchyma harboring an infiltrative lesion arranged in cords trabeculae and acini. the cells have round to oval vesicular nuclei with prominent nucleoli and moderate cytoplasm. adjacent areas shows fibrosis and hyalinisation mitosisare seen.,biopsy from left breast:invasive ductal carcinoma grade ii.tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1712233,right breast u s guided biopsyright breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey brown linear cores measures 1 1.2cm.entire tissue is processed.,section shows cores of fibrous tissue with an infiltrative lesion arranged in tubular and glandular pattern.cells are low columnar with ovoid dark nuclei with stratification and moderate eosinophilic cytoplasm.areas of ductal carcinoma in situ seen.,biopsy from right breast lump.:invasive carcinoma nst with cribriform ductal carcinoma insitugrade i.tubule formation 2nuclear pleomorphism 1mitotic figures 1 4 9
MR1712244,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey brown linear cores measure 0.8 1.2cm.entire tissue is processed.,sections show cores of breast tissue with an infiltrating neoplasm predominantly in sheets.the cells have moderate cytoplasm pleomorphic hyperchromatic nuclei and few showing prominent nucleoli. there is a myxoid desmoplastic stroma.tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9 total score 7grade 2,features are suggestive of invasive carcinoma ductal type mbr score 7.
MR1712252,right breast mass carcinoma breast.,biopsy from right breast mass.,received multiple grey white to grey brown linear cores measures 1 1.4cm.entire tissue isprocessed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderateamount of cytoplasm.,right breast lump core biopsy:invasive ductal carcinoma grade 2.modified bloom richardson score is 6tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1712280,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 4 grey white to grey brown linear cores measures 1.1 to 1cm. entire tissue processed.,section shows cores of fibrocollagenous tissue with an infiltrating neoplasm in a desmoplastic stroma. the tumor cells show vague tubular pattern. the cells show moderate cellular atypia and nuclear pleomorphism and hyperchromatic scattered mitotic figures noted.,biopsy from left breast lump:invasive carcinoma no special type grade 2modified bloom richardson score is 6 9tubule formation 3nuclear pleomorphic 2mitotic figures 1 6 9
MR1712311,ulcer left breast.,biopsy from left breast.,multiple grey white to grey brown soft tissue bits altogether measures 1.5x1x0.5cm. entire tissue processed.,section shows epidermoid with ulceration an extensive neutrophilic excudate layer with karyorrehectic debris. the underlying denses shows scattered and clusters of atypical cells with hyperchromatic bizarre nuclei and scant cytoplasm. atypical mitosis are seen. intervening stroma shows dense lymphoplasmacytic infiltrate.,left breast biopsy:suggestive of invasive carcinoma nst nuclear grade ii.
MR1712325,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey brown linear cores measures 0.6 0.8cm.entire tissue is processed.,sections from the biopsy show cores of breast tissue with an invasive neoplasm composed of cells in sheets and acini showing moderate cellular atypia increased n c ratio and hyperchromatic nuclei.,features are suggestive of invasive carcinoma ductal typenottingham score 7grade ii.
MR1712350,left breast lump carcinoma breast.,left breast lump,received 6 grey white to grey brown soft tissue bits measures 0.6 to 0.8cm. entire tissue processed.,section from breast parenchyma shows lesion arranged in papillary pattern with fibrovascular core in centre. the papillae consists of columnar cells with round to oval nuclei and moderate cytoplasm. the nuclei of the cells show nuclear stratification. areas of fibrosis and hemorrhage seen.,biopsy from left breast lump.suggestive of papillary neoplasm.
MR1712381,right breast lump possibility of carcinoma breast.out side fnac ductal carcinoma breast,biopsy from right breast lump.,received multiple grey white to grey brown linear cores measure 0.8 1.2cm.entire tissue is processed.,sections from the biopsy show cores of breast tissue with an infiltrating neoplasm in a desmoplasticstroma. the neoplastic cells show poorly formed tubules and nests. the cells show moderate cellularatypia with increased n:c ratio and hyperchromatic nuclei few show prominent nucleoli. mitosisis discerned. nottingham score 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9 grade ii,features are suggestive of invasive carcinoma ductal typenottingham score is 6grade ii.
MR1712422,lump in left breast.,a) left sentinel lymph node biopsy.b) left breast lump left breast conserving surgery.,a) received 3 lymph nodes one is inked blue and largest measures 1x0.8x0.6cm. other lymph node measures 1x0.8x0.5cm another measures 1x0.5x0.5cm. isolated 3 lymph nodes.b) received lumpectomy specimen measures 6x4x3.5cm. skin measures 2.5x0.5cm. no scar seen cut surface grey white from lesion tumor measures 3.0x2x1cm. one lymph node measures 0.5x0.3x0.3cm seen abutting the tumor lymph node part of tumor.distance from margins :superior : 1.6cm.inferior : 0.5cm.medial : 0.5cm.lateral : 1.5cm.deep : 0.5cm.,section studied shows breast parenchyma harboring a neoplastic lesion arranged in solid sheets cords and trabeculae. the lesional cells are highly pleomorphic with moderate amount of eosinophilic cytoplasm pleomorphic round to oval vesicular nuclei and prominent nucleoli. few multinucleated giant cells are seen. lymphovascular invasion and perineural invasion is not seen. brisk mitotic activity is seen. adjacent stroma shows desmoplasia. foci of necrosis and karyorrhectic debris are seen.,a) left sentinel lymph node biopsy :six lymph nodes isolated. negative for malignancy (0 6).b) left breast lump left breast conserving surgery. :invasive ductal carcinoma grade 3.modified bloom richardson score is 8(3+3+2).ductal carcinom ain situ is not seen.lymphovascular invasion is not seen.perineural invasion is not seen.all margins of resection are free of tumor.
MR1712435,right breast lump possibility of carcinoma breast.,biopsy from breast lump.,received multiple grey white to grey brown linear cores measures 0.8 1.2cm.entire tissue is processed.,section from the biopsy show multiple cores of tumor tissue showing tubules glandular and nested pattern. the cells show moderate atypia nuclear hyperchromatic and polymorphism. mitosis is increased with atypical forms.tubule formation 2nuclear pleomorphism 2mitotic figures 3 7 9 grade ii.nottingham score 7,features are suggestive invasive carcinoma ductal type.(nottingham score 7)grade ii.
MR1712453,carcinoma breast post opleft lung mass carcinoma lung metastases.,biopsy from left lung mass.,received multiple grey white to grey brown linear cores measures 0.6 1cm.entire tissue is processed.,sections show linear tissue cores showing glandular arrangement micropapillae nestsand cords of neoplastic cells showing increased nucleo cytoplasmic ratio hyperchromasia pleomorphic nuclei with inconspicuous nucleoli and scant amount of cytoplasm. these are surrounded by fibrocollagenous connective tissue lymphocytes plasma cells and few neutrophils.,biopsy from left lung mass:non small cell lung cancer favor adenocarcinoma.
MR1712459,right breast mass carcinoma breast.,biopsy from right breast.,received multiple grey white to grey brown linear cores measures 1.2 to 1.4cm. entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as clusters and in cords. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is elastotic.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 7 9. grade 2 tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1712465,uq left breast swelling 3x4cm ct2n1m0,biopsy from left axillary swelling,received multiple grey white linear core measures 1 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in nests and sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few mitotic figures are discerned. stroma shows desmoplasia with areas of hemorrhage and necrosis. ductal carcinoma in situ solid and comedo necrosis pattern noted . areas of calcification noted. there are lymphoid aggregated amidst the neoplastic cells.,biopsy from left axillary swelling:invasive carcinoma nst grade 2modified bloom richardson score is 7 9.tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9 ductal carcinoma in situ solid and comedonecrosis noted.
MR1712476,right breast lump.,right breast lump core biopsy.,received multiple grey white to grey brown linear core measures 0.6 to 1.2cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in cords and occasional nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy :invasive carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1712519,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey brown linear cores measures 1 1.2cm.entire tissue is processed.,section shows cores of breast parenchyma with an infiltrative lesion arranged in sheets and nests.cells are pleomorphic with hyperchromatic nuclei and moderate eosinophilic cytoplasm. mitotic figures discerned. stroma shows mild mononuclear inflammatory infiltrate. ductal carcinoma in situ solid type noted.,biopsy from right breast lump:infiltrating carcinoma nst grade ii.mbr score 7 9tubule formation 3nuclear pleomorphism 2 mitotic figures 2 7 9
MR1712525,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey yellow linear cores measures 1 1.2cm.entire tissue is processed.,sections from the submitted shows linear cores of fibrohyalinised tissue infiltrated by cordsand aggregates of neoplastic cells. the cells show mild nuclear pleomorphism and has scant to moderate amount of cytoplasm. the neoplastic cells are seen infiltrating the adipocytes. there are foci showing crush artefacts. foci of elastosis seen.,suggestive of invasive carcinoma (nuclear grade2).
MR1712533,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received multiple grey white to grey brown linear cores measures 0.4 0.6cm.entire tissue isprocessed.,sections from the linear cores biopsy submitted show infiltrative islands aggregates and tubulesof neoplastic cells.the nuclei show moderate pleomorphism cytoplasm is moderate in amount. mitotic figures discerned. foci of crush artefacts noted. ductal carcinoma in situ and comedonecrosis not identified.,invasive ductal carcinoma mbr score 7 9 grade ii.
MR1712539,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey brown linear cores measures 1.2 1.4cm.entire tissue is processed.,sections from the biopsy show multiple cores of breast tissue with an infiltrating neoplasm in in tubules glandular pattern. the cells show moderate atypia with nuclear pleomorphismand hyperchromasia mitosis is increased. extensive ductal carcinoma in situ withcomedonecrosis also seen.nottingham score 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2grade ii,features are suggestive of invasive carcinoma ductal typenottingham score is 6grade ii.
MR1712549,left breast lump possibility of carcinoma breast.,left breast lump biopsy.,received multiple grey white to grey brown linear cores measures 1 1.2 cm.entire tissue is processed.,section shows breast parenchyma with an infiltrating lesion arranged in nests cords and singly scattered atypical cells. cells have hyperchromatic to vesicular nuclei. cells exhibit focal marked pleomorphism. stroma shows dense inflammatory infiltrate.brisk mitotic including atypical mitotic figures noted.,left breast lump biopsy :invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+3+2).
MR1712557,carcinoma left breast.,a) left breast left breast conservative surgery ( post lumpectomy post chemo).b) left axillary lymph nodes.,a) received lumpectomy specimen measures 5.8x5x2.5cm. skin ellipse measures 4x1cm. cut surface shows grey white illdefined firm fibrotic areas measures 1x0.5x0.5cm. distance form the margins:superior margin 1.5cm. inferior margin 1.5cm.medial margin 1cm.lateral margin 3cm.deep margin 1cm.representative sections are submitted.b) received fibrofatty tissue measures 6 x 4 x 0.5 cm. eight lymph node isolated largest lymph node measures 0.8 x 0.7 x 0.5 cm. cut surface is unremarkable.,section shows no residual tumor cells are seen. treatment related changes are seen including foamy macrophages lymphocytes and sclerosis. adjacent stroma shows atypical ductal hyperplasia.,a) left breast left breast conservative surgery ( post lumpectomy post chemo) :no residual tumor is seen. treatment related changes are seen. adjacent stroma features of atypical ductal hyperplasia. all margins of resection are free of tumor.b) left axillary lymph nodes :eight lymph nodes are identified negative for malignancy (0 8)
MR1712563,carcinoma right breast.,a) right breast wide local excision.b) right sentinel lymph node biopsy.,a) received lumpectomy specimen measures 7x5.5x4cm. serial section shows grey white lesion measures 2.5x1.8x1.5cm.distance from margins :superior : 2.4cm.inferior : 1.5cm.medial : 1.2cm.lateral : 2cm.deep is muscle : 0.9cm.b) received fibrofatty tissue measures 3.5x2x1cm. largest lymph node measures 2x1.5x0.6cm. cut surface fat impe,a) right breast wide local excision :tumor bed : invasive ductal carcinoma grade ii.modified br score is 7 9tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 few ducts show ductal carcinoma in situ solid type measures 0.5cm. lymphovascular invasion not present.perinerual invasion present.all resected margins free of tumorsuperior free of tumor.inferior margin is free of tumor.medial margin is free of tumor.lateral margin is free of tumor.deep margin is free of tumor.b) right sentinel lymph node biopsy :isolated five lymph nodes negative for malignancy (0 5).,a) right breast wide local excision :invasive ductal carcinoma grade ii.maximum dimension of tumor is 2.5cm.invasive carcinoma is 2cm.ductal carcinoma is 0.5cm.lymphovascular invasion not present.perinerual invaion present.all resected margins are free of tumor.b)sentinel lymph nodes :five lymph nodes no deposits of tumor.
MR1712577,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received 4 grey white to grey brown linear cores measures 0.8 to 1.2cm. entire tissue processed.,sections shows linear cores of tissue fragment harboring an infiltrative lesion arranged in nests cords lobules and trabeculae. the cells have moderately pleomorphic vesicular nuclei prominent nucleoli and moderate to abundant cytoplasm. intervening stroma shows fibrosis and hyalinisation.,left breast lump biopsy:invasive ductal carcinoma grade iimodified bloom richardson score is 6 9.tubule formation 3pleomorphism 2mitosis 1 6 9
MR1712580,right breast lump out side fnac benign breast lesion.,biopsy from right breast.,received multiple fragment linear cores measures 0.6 to 1.2cm. entire tissue processed.,sections shows linear tissue cores showing cords trabeculae and glandular arrangement of neoplastic cells showing increased nucleo cytoplasmic ratio nuclear pleomorphism and hyperchromasia and variable amount of pale eosinophilic cytoplasm. these are surrounded by fibrocollagenous connective tissue with myxoid areas.,biopsy from right breast lump:infiltrating duct carcinoma grade 2modified bloom richardson score is 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2
MR1712583,right breast lump p o carcinoma breast.,biopsy from right breast lump.,received 3 grey white to grey brown linear cores measures 1.2 to 1.4cm. entire tissue processed.,section from the biopsy show cores of fibrocollagenous tissue with an infiltrative neoplasm showing sheets and nests of highly pleomorphic cells and poorly forming glands. there is moderate nuclear pleomorphism and hyperchromatic. there is increased mitosis. no insitu component seen. there is desmoplasia and myxoid change in stroma. tumor appears to infiltrate the fat,biopsy from right breast lump:invasive carcinoma ductal type grade iii.modified bloom richardson score is 8 9tubule formation 3nuclear pleomorphism 2mitotic figures 3 8 9
MR1712626,left breast lump possibility of carcinoma breast.,left breast core biopsy.,received multiple grey white to grey brown linear cores measures 0.5 1cm.entire tissue is processed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1712631,left breast lump p o carcinoma breast.,biopsy from left breast.,received multiple fragment linear cores measures 0.3 to 0.6cm. entire tissue processed.,sections show fragmented tissue bits showing sheets and occasional papillae of neoplastic cells showing increased nucleocytoplasmic ratio nuclear hyperchromatic pleomorphism and variable amount of eosinophilic cytoplasm. these are surrounded by dense fibrocollagenous connective tissue infiltrated by dense mild inflammatory infiltrate composed of neutrophils lympjhocytes plasma cells and eosinophils. areas of necrosis seen.,biopsy from left breast lump:infiltrating duct carcinoma grade 2modified bloom richardson score is 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2areas of necrosis seen.
MR1712649,carcinoma breast post op.liver space occupying lesion metastatic.,liver biopsy.,received multiple grey white to grey brown linear cores ranging from 0.4 to 1.2cm. entire tissue processed.,section shows 4 linear cores of fibrocollagenous tissue harboring a lesion arranged in cords and nests. lesional cells have round to oval hyperchromatic nucleus with moderate cytoplasm. moderate to marked nuclear pleomorphism noted.,liver core biopsy :feature are suggestive of metastatic tumor deposits in a known and treated case of carcinoma breast.
MR1712653,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received 4 grey white to grey brown linear cores measure 1 to 1.2cm. entire tissue processed.,section from the biopsy show cores of breast tissue with an infiltrating neoplasm in a desmoplastic stroma. the cells show vague tubular arrangement .the cells show high n c ratio hyperchromatic nucleus and moderate nuclear pleomorphism. mitosis is increased with many atypical forms. necrosis present.,invasive carcinoma no special type.left breastmodified bloom richardson score is 7 9 grade 2tubule formation 3nuclear pleomorphism 2mitosis 2 7 9
MR1712701,left breast mass carcinoma breast.,biopsy from left breast mass.,received 3 tiny grey white to grey brown linear cores measures 0.8 to 1.2cm. entire tissue processed.,section from the biopsy show cores of breast tissue with glands and ducts showing extensive ductal carcinoma in situ in cribriform and comedo pattern. few cores show an invasive neoplasm in sheets and nests.the cells show moderate nuclear pleomorphism. mitosis is increased. there is lymphoplasmacytic infiltration around the tumor.,biopsy from left breast mass:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9 (3+2+2).with ductal carcinoma in situ and comedonecrosis.
MR1712719,a) right hemithyroidectomy specimen.b) left modified radical mastectomy specimen.,a) right hemithyroidectomy,received a lobe of thyroid with part of isthmus measuring 4x2.5x1.5cm. cut surface shows circumscribed.greywhite to grey yellow lesion measuring 1.5x0.8x0.6cm.distance from nearest inked margin measuring 0.5cm.areas of calcification noted.b) left modified radical mastectomy,received in : formalin.procedure : mastectomy.laterality : left breast.total dimensions :medial lateral :18cm. superficial deep : 4cm. superior inferior :17cm.skin ellipse : 12 x 7 cm. puckering noted lateral to nipple areola complex.nipple : normalscar surgical defect : not seen.tumor : single.tumor size : 1.5x1x1cm.location of tumor : corresponding to skin puckering : upper outer quadrant.margins of tumor : ill defined.deep margin : 2cm.muscle : absent.adjacent breast : fibrotic areas noted.total number of nodes : 8nodes.axillary tail : 5x5x2cm.size of largest node : 1.8x1x0.8cm. cut surface shows fatty infiltration.,a) colloid nodular hyperplasia with an adenomatoid nodule right hemithyroidectomy.b) no residual invasive tumor left mrm status post nact.foreign body multinucleated giant cell reaction seen in lumpectomy bed.skin nipple areola : free of tumor.posterior resection margin : free of tumor.8 left axillary lymph nodes isolated are free of tumor.
MR1712735,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey yellow linear cores measures 1.2 1.5cm.,sections from the biopsy show fibroadipose tissue with an invasive neoplasm predominantly in nests and sheets. the cells have abundant to moderate eosinophilic cytoplasm well definedcell borders round to oval nuclei and prominent nucleoli. mitosis is increased. comedonecrosis is also seen.mbr score 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9 grade ii.,invasive carcinoma with apocrine features mbr score 6 9grade ii.
MR1712737,carcinoma right breast ( post lumpectomy +nact).,a) wide local excision of previous lumpectomy siteb) revised inferior margin.c) level iii lymph nodes right.d) right axillary lymph nodes.,a)received lumpectomy specimen measuring 8x5.5x2.5cm. skin ellipse measures 5x1.5cm. cut surface shows grey white firm ill defined area measuring 2.5x2x0.6cm. distance from respective margins :superior : 2cm.inferior : 0.3cm.medial : 2.5cm.lateral : 2.5cm.deep : 0.3cm.b) received grey white flap like tissue measuring 5x2x0.5cm.entire tissue processed.c) received fibrofatty tissue measures 3x2x0.5cm. entire tissue processed.d) received one fibrofatty tissue measuring 6x 5x2 cm. largest lymph node measures 2.5x1x0.6cm. cut surface shows fatty infiltration.,wide local excision right breast(post lumpectomy and nact) :lumpectomy bed : the section shows fibrotic necrotic areas and atrophic ducts. surrounding breast parenchyma shows adenosis and epithelial hyperplasia. there is no evidence of residual viable tumor present.superior margin : free of tumor.inferior margin : shows adenosis and epithelial hyperplasia there is no evidence of malignancy.medial margin : free of tumor.lateral margin : free of tumor.deep margin : free of tumor.b) revised inferior margin : shows fibrofatty tissue which is free of tumor.c) level iii nodes right side : 6 nodes :show no metastatic deposits of tumor.d) right axillary lymph nodes : 14 nodes show no metastatic deposits of tumor.,wide local excision right breast(post lumpectomy and nact) : :no residual viable tumor present.resected margins : superior medial lateral and deep are free of tumor.revised inferior margin : free of tumor.level iii nodes right side : 6 nodes :show no metastatic deposits of tumor.right axillary lymphnode : 14 nodes show no metastatic deposits of tumor.
MR1712739,carcinoma right breast post neoadjuvant chemotherapy.,right breast right modified radical mastectomy (post nact).,received in : formalinprocedure : modified radical mastectomylaterality : right total dimensions : medial to lateral : 21 cm. superficial to deep : 3.5 cm. superior to inferior : 20 cm.skin ellipse : 17 x 10 cm. nipple : normal scar surgical defect : not seen.tumor : singletumour size : 1.2 x 0.8 x 0.8 cm. location of tumor : lower central quadrant. margins of tumor : illdefined. deep margin : 1.5 cm.muscle : absent adjacent breast : fibrofatty tissue. axillary tail : 4 x 3 x 2 cm.size of largest node : 2 x1 x 0.8 cm. cut surface grey white.representative sections are submitted.,section show residual tumor cells in diffuse sheets and nests. individual tumor cells have hyperchroamtic nuclei and moderate amount of cytoplasm. lymphovascular invasion is seen. perinerual invasion is not seen.,right breast right modified radical mastectomy (post nact) :residual invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). tumor measures 1.2 cm in greatest dimension and is located in the lower central quadrant. ductal carcinoma in situ of solid and comedo pattern with intermediate nuclear grade is seen. lymphovascular invasion is identified. perineural invasion is not identified. posterior resection margin is free of tumor nipple and areola are free of tumor.lymph nodes : one out of twelve lymph nodes shows metastatic tumor deposits (1 12). size of the tumor deposits measures 0.8 cm in greatest dimension. no extranodal extension is seen.pathological stage : ypt1cn1a
MR1712753,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received 4 grey white to grey brown linear cores measures 1 to 1.4cm. entire tissue processed.,section from the biopsy show cores breast tissue with an infiltrating neoplasm. predominantly in sheets nests and vague tubular glandular pattern. the cells show moderate cellular atypia nuclear pleomorphism and hyperchromatism. few show cytoplasmic clearing and vacuolation. there is ductal carcinoma in situ component with comedo necrosis.,biopsy from right breast:invasive carcinoma ductal typemodified bloom richardson score 6 9 grade 2.tubule formation 3nuclear pleomorphism 2mitosis 1 6 9
MR1712760,right breast lump malignant.,biopsy from right breast.,received 4 grey white to grey brown linear cores measures 1.2 to 1.4cm. entire tissue processed.,section from the biopsy show cores of fibro adipose tissue with an infiltrating neoplasm composed of cells in sheets nests and tubules. the cells the highly pleomorphic with moderate cytoplasm. increased n c ratio pleomorphic hyperchromatic nuclei and prominent nucleoli. mitosis is increased with atypical forms.,biopsy from right breast:invasive carcinoma ductal typemodified bloom richardson score 8 9 grade 3.tubule formation 2nuclear pleomorphism 3mitosis 3 8 9
MR1712772,recurrent papillary carcinoma right breast.,a) right breast right lumpectomy.b) right sentinel lymph node biopsy.c) right nodule beneath serratus muscle.d) right breast mastectomy.,received in : formalin.laterality : right mrm total dimensions : medial to lateral : 18cm. superficial to deep : 4.5cm. superior to inferior : 14cm.skin ellipse : 12x6.5cm. nipple : normal skin surface shows surgical depect : 4.5x2cm.lumpectomy bed : 10x8x4cm. deep margin : 4.5cm.muscle : absent adjacent breast : fibrofatty. axillary tail : absent.,section show breast parenchyma harboring an infiltrating lesion arranged in lobules separated by fibrocollagenous bands within the lobules the cells are arranged in sheets and focal papillary pattern. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. stroma shows desmoplasia with lymphomononuclear infiltrates. mitotic figures are discerned.,a) right breast right lumpectomy :known case of carcinoma right breast underwent excision biopsy.recurrent invasive papillary carcinoma.modified br score is 7 9tubular formation : 3nuclear pleomorphism : 2mitotic activity : 2 7 9 tumor measures 2.2cm in greatest dimension.lymphovascular invasion is not identified.perineural spread is not identified.ductal carcinoma in situ is not seen.b) right sentinel lymph node biopsy :isolated ten lymph nodes are free of tumor (0 10).c) right nodule beneath serratus muscle :isolated one lymphnode shows tumor deposits (1 1).tumor deposit measures 0.9cm in greatest dimension.extranodal extension is not seen.inked surface is 0.2cm away from tumor.d) right breast right modified radical mastectomy post lumpectomy : no residual tumor.lymphovascular invasion : not present.perineural invasion : not present.posterior resection margin is free of tumor.nipple and areola : unremarkable.summary :right lumpectomy shows recurrent invasive papillary carcinoma grade 2 .tumor measures 2.2cm in greatest dimension. however completion mastectomy specimen done shows no evidence of residual tumor and its deep margin is free of tumor. one of eleven isolated lymphnodes show metastatic tumor deposits (1 11).extranodal extension is not seen.
MR1712810,right breast lump suspicious lesion.,right breast lump biopsy.,received 4 grey white to grey brown linear cores measures 1 to 1.2 cm. entire tissue processed.,section shows breast parenchyma harboring a lesion arranged in nests cords and tubules. cells have hyperchromatic nuclei and moderate amount of cytoplasm. stromal desmoplasia noted. mitotic figures discerned.,right breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1712834,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received 3 grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section from the biopsy show cores of breast tissue with an infiltrative neoplasm is sheets nests the cells show moderate cellular atypiai increased n c ratio nuclear hyperchromatism and pleomorphism. mitosis is increased. in situ component with comedo necrosis also noted. there is focal lymphoplasmacytic infiltration.,biopsy from right breast:invasive carcinoma ductal typemodified bloom richardson score 7 9 grade iii.tubule formation 3nuclear pleomorphism 2mitosis 3 8 9
MR1712863,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey brown linear cores measures 1.2 1.4cm.entire tissue is processed,multiple linear cores showing infiltrative lesion arranged in nests cribriform islands the background of mucin. the cells forming the lesion are round to oval hyperchromatic nuclei scantmoderate cytoplasm. adjacent stroma shows mild inflammatory infiltrates composed oflymphocyets. mitoses 3 4 10hpf.,biopsy from right breast lump:invasive carcinoma with mucinous features.
MR1712889,mass in right breast carcinoma breast.,biopsy from right breast mass.,received multiple grey white to grey brown linear cores measures 1 1.2cm.,section show multiple fragments of breast parenchyma with infiltrative lesion arranged innests tubules. the cells forming the lesion are round to oval hyperchromatic nuclei with moderate eosinophilic cytoplasm. adjacent shows inflammatory cells composed of lymphocytes and plasma cells.mitoses 3 4 10hpf.,right breast biopsy:invasive ductal carcinoma grade 2.mbr score 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1712900,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white to grey brown linear cores measures 0.8 1cm.entire tissue is processed.,multiple fragments of breast parenchyma showing infiltrative neoplasm arranged in tubules and nests. the cells forming the lesion are round to oval nuclei abundant eosinophilic cytoplasm prominent nucleoli hyperchromatic nuclei seen. adjacent stroma showing inflammatory infiltrates composed of lymphocytes and neutrophils. mitoses 5 6 10hpf.,left breast lump biopsy invasive ductal carcinoma grade 2.mbr scor e 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1712905,left breast lump possibility of carcinoma breast.,left breast lump biopsy.,received 3 grey white to grey brown linear cores measures 0.7 to 1.2 cm. entire tissue processed.,section shows breast parenchyma harboring a lesion arranged in tubules cords and sheets. cells have hyperchromatic nuclei and moderate cytoplasm. stroma shows desmoplasia. mitotic figures discerned.,left breast lump biopsy :invasive ductal carcinoma grade 1 modified bloom richardson score 5(2+2+1).
MR1712918,left breast mass carcinoma breast.,left breast mass,received 4 grey white to grey brown linear cores measures 0.5 to 1cm. entire tissue processed.,section shows linear cores of tissue harboring a neoplastic lesion arranged in nests islands and sheets. the cells have round to oval pleomorphic hyperchromatic to vesicular nuclei and abundant cytoplasm few of the cells show clear cytoplasm. intervening stroma shows fibrosis and lymphocytic infiltrate. mitotic activity are seen.,left breast massinvasive carcinoma nst grade 2modified bloom richardson score is 7 9tubule formation 3nuclear pleomorphism 2mitosis 2 7 9
MR1712931,left breast lump p o carcinoma breast.,biopsy from left breast lump.,received multiple grey white to grey brown linear cores measuring 0.8 to 1.2cm. entire tissue processed.,section from the biopsy show breast tissue with an invasive neoplasm showing papillary features. the cells show moderate pleomorphism moderate amount of cytoplasm round to oval hyperchromatic nuclei. stroma shows extensive hyalinization.,biopsy from left breast lump:features are highly suspicious of papillary carcinoma.repeat biopsy is suggested for confirmation and receptor status as the tumor is minimal .
MR1712933,right supraclavicular lymph node.,right supraclavicular lymph node.,received multiple grey white to grey brown linear cores measures 0.3 to 0.5cm. entire tissue processed.,section shows cores of fibrous tissue with an infiltrative lesion arranged in glands and in micro papillae.the cells exhibit pleomorphic hyperchromatic nuclei and moderate eosinophilic cytoplasm. few cells show intranuclear inclusions. mitotic figures discerned. stroma shows lymphocytic infiltration.,right supraclavicular lymph node:metastatic adenocarcinoma please look for primary lung genital tract and breast.
MR1712966,right lump possibility of carcinoma breast.,right breast lump biopsy.,received 4 grey white to grey brown linear cores measures 1.2 to 1.4cm. entire tissue processed.,section shows cores of breast parenchyma harboring a lesion arranged in nests sheets tubules and cords. cells have hyperchromatic nuclei and moderate amount of cytoplasm. mitotic figures discerned. stroma fibrosis noted.,right breast lump biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score 6(3+2+1).
MR1712973,right breast lump p o carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue processed.,section from the biopsy shows cores of fibrocollagenous tissue with an invasive neoplasm arranged in sheets and nests. the cells show moderate pleomorphism and hyperchromatic nuclei with prominent nucleoli. mitosis is increased with many atypical forms.,biopsy from right breast lump:invasive ductal carcinoma nos. grade lll.modified bloom richardson score is 8 9.tubular formation 3nuclear pleomorphism 2mitotic figures 3 8 9
MR1712991,case of right breast mass suspicious of malignancy.,right breast lump core biopsy.,received 5 grey white to grey brown linear cores measures 0.8 to 1.2 cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1713003,ovrian mass carcinoma ovary.,biopsy from ovarian mass.,received multiple grey white to grey brown linear cores measures 0.6 to 1cm. entire tissue processed.,section shows linear cores of fibrous tissue harboring an infiltrating lesion arranged in sheets clusters and discretely signet sing cells. the cells are ovoid having moderate amount of cytoplasm and hyperchromatic nucleus. mitotic figures are discerned. stroma shows desmoplasia with areas of hemorrhage and necrosis.,biopsy from mass:signet sing cells fragment possibility considered are 1. metastasis from stomach breast ( lobular signet ring cell type).2. signet ring stromal tumor.suggest ihc and clinical correlation.
MR1713073,right breast mass malignancy.,right breast mass core biopsy.,received 6 grey white to grey brown linear cores measures 1 to 1.2 cm.entire tissue processed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei with moderate amount of cytoplasm.,right breast mass core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1713140,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received 3 grey white to grey brown linear cores measures1.2 to 1.4cm. entire tissue processed.,section shows breast parenchyma with an infiltrative lesion arranged in cords tubules. cells show pleomorphic vesicular nuclei prominent nucleoli and moderate eosinophilic cytoplasm. mitotic figures discerned. ductal carcinoma in situ with comedo necrosis seen. stroma shows hyalinisation and lymphocytic infiltration.,biopsy from right breast lump:invasive carcinoma grade iimodified bloom richardson score is 6 9.tubule formation 2nuclear pleomorphism 2mitosis 2 6 9 ductal carcinoma in situ comedonecrosis seen
MR1713179,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received 4 grey white to grey brown linear cores measures 1 to 1.2 cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. areas of comedo necrosis is seen.,right breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1)
MR1713250,carcinoma right breast..,biopsy from right breast,received 5 grey white linear cores measuring 1 to 1.4cm. entire tissue processed.,sections show multiple cores of breast tissue with an infiltrating neoplasm predominantly in sheets nests cords and vague glandular pattern. the cells show moderate nuclear pleomorphism hyperchromatism and increased mitosis. adjacent ductal carcinoma in situ with solid pattern seen. extensive intra and peritumoral inflammation noted.,biopsy from right breast:features suggestive of invasive carcinoma ductal (nst)modified bloom richardson score is 6(3+2+1). grade 2.focus of ductal carcinoma in situ in solid pattern seen.
MR1713267,carcinoma left breast post nact.,left modified radical mastectomy.,received in : formalinprocedure : modified radical mastectomy laterality : left total dimensions : medial to lateral :21cm superficial to deep : 3.5cm superior to inferior :14cmskin ellipse :16x9cm nipple :normalscar surgical defect :not seentumor : singletumor size : 4.8x4x2.5cmcm location of tumor : upper outer quadrantmargins of tumor : ill defined deep margin : 1cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail :9x5x3.5 cmsize of largest node :2.5x1.5x1.5cm cut surface grey white,multiple section studied show breast parenchyma harboring an infiltrative neoplasm arranged as cores and tubules of neoplastic cells exhibiting increased n c ratio pleomorphic vesicular nuclei prominent nucleoli and scanty to moderate amount of pale eosinophilic cytoplasm. there is brisk mitotic activity with numerous atypical mitotic figures. necrotic foci are noted. intervening stroma shows dense fibrocollagenous connective tissue . the deep margin is uninvolved by tumor. the nipple and areola are free of tumor. lymphovascular embolus is seen.perineural invasion not identified. 15 lymph nodes identified 12 shows evidence of metastatic tumor deposit. largest measures 2.5cm in greatest dimension. perinodal spread noted.,left breast left modified radical mastectomy:invasive ductal carcinoma nst grade iiimodified bloom richardson score is 8 9 tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3tumor measures 4.8cm in greatest dimension is located in the upper outer quadrant.ductal carcinoma in situ not seenlymphovascular invasion identifiedperineural invasion not identifiedposterior resection margin is free of tumor.nipple and areola is free of tumorlymph nodes 15 lymph nodes few metastatic 12 (12 15)pathological state ypt2n3.summary: left modified radical mastectomy post nact invasive carcinoma nst grade iii.nodal metastases 12 15.
MR1713301,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures1.2 to 2cm. entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged in islands and nests . the neoplastic cells are round to polygonal have hyperchromatic to vesicular nuclei conspicuous nucleoli and moderate cytoplasm. areas of necrosis.,biopsy from left breast lump:invasive ductal carcinomamodified bloom richardson score is 7 9 grade 2tubule formation 3nuclear pleomorphism 2mitosis 2 7 9
MR1713308,left breast lump.,left breast lump core biopsy.,received multiple grey white linear cores measures 0.5 to 1 cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in nests cords and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1713318,left carcinoma breast.,a) breast conservative surgery wide excision.b) left axillary sentinel lymph node.c) revised medial margind)left axillary nodes.,a) received lumpectomy specimen measures 5x4.5x3cmskin measures 5x2.1cmsection shows grey white lesion measures 1.7x1.6x0.9cmdistance from margins:superior margin : 1.5cminferior margin : 1cmmedial margin : 0.2cmlateral margin : 1.5cmdeep margin : 0.7cmb) received multiple fibrofatty tissue altogether measures 2x1.5x1cm isolated 3 lymph nodeslargest lymph node measures 1x0.8x0.5cm.c) received single fibrofatty tisue measures 4x1.8x1cmone surface inked.d) received fibrofatty tissue measures 5.5x4.5x2.5cm.dissected node 11 lymph nodes.,tumor: the section shows diffuse sheets clumps of pleomorphic cells with hyperchromatic nucleus and scanty cytoplasm. tubular formation lessthan 10 3 mitotic figures 8 10 2 nuclear pleomorphism 2. mbr score is 7 9 nuclear grade 2.,a)breast conservative surgery wide excisioninvasive ductal carcinoma nuclear grade iimaximum dimension of tumor measures 1.7x1.6cmductal carcinoma in situ not identified.lymphovascular invasion not identifiedperineural invasion not identified.resected margin :superior margin inferior margin lateral and deep margin : free of tumorrevised medial margin : free of tuor.b)left sentinel lymph nodes:3 nodes no deposits of tumorc)resected medial margins:fibrofatty tissue free of tumord)left axillary lymph nodes: 11 nodes no deposits of tumor.pathological stage: pt1n0
MR1713339,right breast lump p o malignancy.,right breast lump biopsy.,received multiple grey white linear core measures 1.2 to 1.4cm. entire tissue processed.,section shows cores of breast parenchyma harboring a lesion arranged in nests. sheets cords and tubules. cells have hyperchromatic nuclei and shows moderate pleomorphism . stromal shows fibromyoxiod change and lymphocytic infiltration. few ducts show ductal carcinoma in situ with comedonecrosis.,right breast lump biopsy:invasive ductal carcinoma grade 2.modified bloom richardson score 7 (3+2+2).
MR1713396,right breast lump h o mother died of carcinoma breast.,right breast lump core biopsy.,received 5 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section shows cores of fibrocollagenous tissue with occasional ductules lined by columnar cells. no atypia is seen.,right breast lump core biopsy :shows benign breast tissue.negative for malignancy.
MR1713397,right breast lump carcinoma breast.,biopsy from right breast.,received 6 greywhite linear core ranging from 0.8 to 1.2cm. entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as cords tubules and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. foci of high grade dcis noted.,infiltrating ductal carcinoma biopsy from right breast.modified br score : 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1713418,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as tubules cords and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is elastotic.,biopsy from left breast lump:infiltrating ductal carcinoma modified bloom richardson score is 6 9 grade 2.tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1713482,left breast possibility of carcinoma breast.,left breast lump core biopsy.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1713607,carcinoma left breast lump.,a) biopsy from left breast lump.b) left axillary,received lumpectomy specimen measures 7x5x1.5cm. skin ellips measures 5x3cm. cut surface shows an illdefined fibrosis areas measures 1.5x1x1cmdistance from margin:superior margin :1.5cminferior margin : 0.6cmmedial margin : 5cmlateral margin : 0.5cmdeep margin : 0.1cmcut surface few grey yellow nodule calcification.b) received fibrofatty measures 11x9x3cm largest lymph nodes measures 2x1.5x0.5cm. cut surface grey brown.,no residual viable tumor present . section show benign breast tissue areas of hyalinsation foreign body giant cell reaction and scattered histocytic aggregates.,a) left breast post lumpectomy + nact lobr focal excision o residual massno residual viable tumor presentall resected margins are free of tumor.no evidence of lymphovascular or perineural invasion.b) left axillary :ten lymph nodes isolated all are free of tumor pathological stage : ypt0n0
MR1713630,right breast mass p o carcinoma.,right breast mass.,received 5 greywhite to greybrown linear cores measuring 1 to 1.4cm. entire tissue processed.,section shows cores of fibrous tissue with an infiltrative lesion arranged in cords and diffuse sheets. cells are markedly pleomorphic with vesicular nuclei prominent nucleoli and moderate eosinophilic cytoplasm. mitotic figures discerned. adjacent focus show multinucleated giant cells and aggregates of histiocytes. marked peritumoral lymphocytic infiltration noted.,right breast mass:invasive carcinoma with medullary features nuclear grade 3.granulomatous inflammation also noted.
MR1713631,right breast lump.,right breast lump core biopsy.,received 7 greywhite linear core ranging from 1 to 1.4 cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in cords and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). ductal carcinoma in situ of cribriform and comedo pattern with intermediate nuclear grade is seen.
MR1713637,right breast limp carcinoma breast.,right breast lump biopsy.,received multiple grey white to grey brown linear cores ranging from 1.2 to 1.5cm. entire tissue processed.,sections show breast tissue with an invasive neoplasm amonged in cords and glandular pattern surrounded by desmoplastic stroma. the cells show moderate nuclear pleomorphism and prominent nucleoli. mitosis is increased.,right breast lump biopsy:suggestive of invasive carcinoma nos grade iii.modified bloom richardson score 8.tubular formation 2nuclear pleomorphism 3mitotic figures 3 8 9 .
MR1713648,left breast lump p o carcinoma breast.,biopsy from left breast.,received 4 greywhite to greybrown linear cores measuring 1.2 to 1.5cm. entire tissue processed.,section shows cores of fibrous tissue with an infiltrative lesion arranged in tubules and cords. cells are moderately pleomorphic with hyperchromatic ovoid nuclei and moderate eosinophilic to clear vacuolated cytoplasm. stroma shows lymphocytic infiltration.,biopsy from left breast:invasive carcinoma nuclear grade 2 (patchy intraluminal mucin production).
MR1713669,case of right breast carcinoma.,right breast right modified radical mastectomy(post lumpectomy).,received in : formalin.laterality : right total dimensions : medial to lateral : 18 cm. superficial to deep : 4 cm. superior to inferior : 17 cm.skin ellipse : 16 x 12 cm. nipple : normal scar surgical defect : seen measuring 3 cm in the lower outer quadrant at 4.5 cm away from nipple areola complex.lesion size : 2 x 1.8 x 1.5 cm.location of tumor : lower outer quadrant. margins of tumor : ill defined. deep margin : 0.1cm.muscle : absent adjacent breast : fibrofatty tissue. axillary tail : 7 x 6 x 2.5 cm.size of largest node : 2 x 2 x 1 cm. cut surface shows fatty infiltration.representative sections are submitted.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular or perineural invasion is not seen.,right breast right modified radical mastectomy( post lumpectomy) :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2). tumor is located in the lower outer quadrant. multiple (two) tumor foci are seen larger measuring 1.8 cm in greatest dimension. ductal carcinoma in situ is not seen. lymphovascular invasion is not seen. perineural invasion is not seen. posterior resection margin is free of tumor. nipple and areola is free of tumor.lymph nodes: fifteen lymph nodes are identified negative for malignancy (0 15).pathological stage : pt1cn0
MR1713696,left breast lump malignant,biopsy from left breast,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of tissue with an infiltrating neoplasm predominantly in sheets cords and glandular pattern. the cells show moderate nuclear atypia with prominent nucleoli and clean to eosinophilic vacuolated cytoplasm. stroma is decresly hyalinised and desmoplastic.,left breast:invasive carcinoma ductal type (nos)nuclear grade ii.
MR1713714,left breast lump possibility of carcinoma breast,biopsy from breast.,received 6 grey white linear cores measures 0.6 to 1.2cm. entire tissue processed.,section shows multiple cores of fibro adipose tissue with an infiltrative neoplasm predominantly in sheets and nests. the cells have moderate cellular atypia and nuclear pleomorphism. few show squamoid differentiation with keratinisation. mitosis is increased.,biopsy from breast:invasive high grade carcinoma favoring metaplastic carcinoma with squamoid differentiation.nuclear grade iii.
MR1713832,right breast mass carcinoma breast.,biopsy from right breast.,received multiple grey white linear cores ranging 0.4 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in cords and sheets. lesional cells are pleomorphic having round to irregular hyperchromatic nucleus moderate cytoplasm.,biopsy from right breast :invasive duct carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1713871,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white to grey brown linear cores measures 0.5 to 1.2 cm. entire tissue processed.,section show multiple cores of breast tissue with an invasive neoplasm predominantly an sheets nests and cords. the cells show marked nuclear pleomorphism moderate eosinophilic cytoplasm and increased mitosis.,biopsy from left breast lump:invasive carcinoma ductal type (nos)modified bloom richardson score is 9 9 grade 3tubule formation 3 nuclear pleomorphism 3mitotic figures 3 9 9
MR1713873,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey brown linear cores measures 0.5 to 1cm. entire tissue processed.,section shows cores of fibro adipose tissue with an infiltrative neoplasm predominantly in sheets and cords. the cells show moderate nuclear pleomorphic with eosinophilic to clear cytoplasm and prominent nucleoli. mitosis is increased micro calcification seen.,biopsy from right breast lump:invasive carcinoma ductal type (nos)modified bloom richardson score is 8 9 grade 3tubule formation nuclear pleomorphism 3mitotic figures 2mitotic figures 3 8 9
MR1713881,left carcinoma breast post nact.,left breast left modified radical mastectomy.,received in : formalin.procedure : modified radical mastectomy. laterality : left. total dimensions : medial to lateral :18cm. superficial to deep :3cm. superior to inferior :17cm.skin ellipse :15x11cm. nipple :cut surface shows nodule measures 2x2x1cm. scar surgical defect :absent.tumor bed : single.tumour bed size : 2.5x2x1.5cm. location of tumor bed : retroareolar extending to nipple areola. margin of tumor bed : illdefined.deep margin : 3.5 cm.muscle : absent.adjacent breast : fibrofatty tissue. axillary tail : 8.5x4x3cm. size of largest node : 3x2x1.5cm.,section shows no residual tumor cells. treatment related changes are seen including necrosis sclerosis pigmented macrophages cholesterol clefts lymphocytes and congested capillaries.,left breast left modified radical mastectomy( post nact):no residual tumor is seen. treatment related changes are seen. nipple and areola are free of tumor. posterior resection margin is free of tumor.lymph nodes:seventeen lymph nodes are identified negative for malignancy( 0 17).pathological stage: ypt0n0
MR1713886,left breast lump possibility of carcinoma breast.,left breast lump core biopsy.,received 4 grey white to grey brown linear cores measures 0.8 to 1.2cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in nests and diffuse sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1713889,known case of carcinoma right breast.,a) right axillary lymph node.b) right axillary lymph node dissection.,a) received skin covered fibrofatty tissue measures 10x6x4cm. skin ellipse measures 7x3cm. surface show healed scar measures 3cm. cut surface grey white ill defined lesion measures 1.5x1x1cm. distance from margins : superior margin : 1.0 cm.inferior margin : 1.5 cm.medial margin : 1.0 cm.lateral margin : 1.5 cm.deep margin : 2.0 cm.b) received fibrofatty tissue measures 10x6x2cm. largest lymphnode measures 2x1x1cm. cutsurface fatty infiltrate.,section show breast parenchyma harboring lesion arranged in sheets and cords. the lesional cells are round to oval having vesicular nuclei prominent nucleoli and moderate nuclear pleomorphism.stroma shows lymphocytic infiltrate.,a) right breast conservative surgery post lumpectomy post + nact. invasive carcinoma nst grade 3. lumpectomy site. modified br score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 ................. 8 9 .................. tumor measures 1.5cm in greatest dimension. lymphovascular invasion identified. perineural invasion not identified. all resected margins including deep margin are free of tumor. b) right axillary lymph node dissection:one out of nine lymph nodes show metastatic tumor deposit measures 0.8cm in greatest dimension (1 3) no extra nodal spread seen.
MR1713894,right breast lesion malignancy.,right breast biopsy.,received 4 grey white linear cores measures 0.9x1.2cm. entire tissue processed.,section shows multiple cores of fibroadipose tissue with an infiltrating neoplasm composed of cells in diffuse sheets and cords. the cells show moderate nuclear pleomorphism and increased mitosis.,right breast biopsy:features are suggestive of invasive carcinoma ductal type (nos) grade ii.modified bloom richardson score is 7 9.tubular formation 3.nuclear pleomorphism 2mitotic figures 2 7 9
MR1713902,right breast mass malignant.,biopsy from right breast mass.,received 4 grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords trabeculae. the cells are pleomorphic with round to oval hyperchromatic to vesicular nuclei and moderate cytoplasm. intervening stroma shows lymphocytic infiltrate and hyalinisation.,biopsy from right breast mass:invasive carcinoma.modified bloom richardson score is 6 9 grade 2.tubular formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1713930,left breast lobular carcinoma.right breast lump right supero lateral quadrant lump suspicious.multiple papillary lesions noted.,biopsy from right breast.,received multiple grey white to grey brown linear cores ranging from 0.6 to 1.2cm. entire tissue processed.,sections shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in nests cords and sheets. the cells have round to oval vesicular nuclei few showing prominent nucleoli and moderate cytoplasm. mitotic seen areas of hyalinisation seen.,biopsy from right breast:invasive carcinoma grade 2.modified bloom richardson score is 6 9.tubule formation 3.nuclear formation 2mitotic figures 1 6 9
MR1713944,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received 4 grey white to grey brown linear cores measures 0.5 to 1.0cm. entire tissue processed.,section shows multiple cores of fibroadipose tissue with an invasive neoplasm in sheets. there is moderate nuclear atypia with increased mitotic figures. there is moderate amount of eosinophilic cytoplasm. there is intra and peritumoral inflammation,biopsy from left breast lump:suggestive of invasive carcinoma ductal type (nos)modified bloom richardson score is 8 9 grade ii.tubule formation 3nuclear pleomorphism 2mitotic figures 3 8 9
MR1713959,carcinoma breast.,biopsy from left lung mass.,received multiple grey white to grey brown i linear cores measures 1.0 to 1.4cm. entire tissue processed.,section shows linear cores of lung parenchyma and cartilage harboring an infiltrating lesion present predominantly in stroma arranged in sheets. the cells are polygonal having moderate amount of pale eosinophilic to clear cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with areas of hemorrhage.,biopsy from left lung mass:poorly differentiated carcinoma. metastatic primary.suggest ihc.
MR1713985,right breast lump p o carcinoma breast.,right breast lump core biopsy.,received multiple grey white to grey brown linear cores measures 0.8 to 1.2cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1714014,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received 4 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section shows cores of fibro adipose tissue with an invasive neoplasm composed of cells in sheets nests and glands. the cells show marked nuclear pleomorphism with eosinophilic to clear cytoplasm. microcalcification seen . ductal carcinoma in situ comedo type present,biopsy from left breast lump:invasive carcinoma ductal type (nos)modified bloom richardson score is 7 9 grade 2tubule formation 2nuclear pleomorphism 3mitotic figures 2 7 9 tiny focus of ductal carcinoma in situ with comedo necrosis seen.
MR1714017,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received 4 grey white linear cores measures 0.8 to 1.2cm. entire tissue processed.,section shows multiple cores of breast tissue with an invasive neoplasm is nests and glands. the cells show moderate cytoplasm moderate nuclear pleomorphism and increased mitosis extensive intra and peritumoral inflammation seen.,biopsy from left breast lump:suggestive of invasive carcinoma ductal (nos)modified bloom richardson score is 7 9 grade ii.tubule formation 2nuclear pleomorphism 2mitotic figures 3 7 9
MR1714030,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received 3 grey white linear cores measures1 to 1.2cm. entire tissue processed.,section show multiple cores of breast tissue along with skin with few cores showing foci of an invasive neoplasm in nests and glands and cords showing moderate nuclear pleomorphic clear to eosinophilic cytoplasm and prominent nucleoli.,biopsy from right breast lump:suggestive of invasive carcinoma nosnuclear grade 2note: in view of excessive desmoplasia and paucity of tumour cells repeat biopsy is suggested for erpr her2neu study
MR1714034,carcinoma breast right breast lump.,a) sentinel lymph node.b) right breast right breast conservation surgery.c) revised superior margin.,a) received three lymph nodes largest lymph node measures 1 x 1 x 1 cm fatty infiltration. entire tissue processed.b) received skin covered fibrofatty tissue measures 9 x 7 x 4.5 cm. skin ellipse measures 4.5 x 3 cm surface unremarkable serial slicing shows grey white firm ill defined lesion seen measures .8 x 1.5 x 1.2 cm located at following distance.superior : 1 cm.inferior : 2 cm.medial : 2 cm.lateral : 1.5 cm.deep : 1.5 cm.representative sections are submitted.c) received skin covered single fibrofatty tissue measures 7 x 6 x 2 cm. skin ellipse measures 7 x 0.5 cm. surface unremarkable.,section show fibroglandular tissue infiltrated by tumor cells arranged predominantly in cords and nest. the cells have hyperchromatic round to irregular nucleus moderate cytoplasm. moderate nuclear pleomorphism noted.,a) sentinel lymph node( frozen section) :seven lymph nodes are identified negative for malignancy (0 7).b) right breast right breast conservation surgery :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). tumor measures 1.8 cm in greatest dimension. ductal carcinoma in situ component is not seen. lymphovascular invasion is not identified. perineural invasion is not identified. inferior medial lateral and deep margins of resection are free of tumor.c) revised superior margin :free of tumor.pathological stage : pt1cn0
MR1714071,known case of carcinoma right breast.,biopsy from right breast.,received 4 grey white to grey white linear cores measures 1 to 1.2cm. entirei tissue processed.,sections from breast harbours tumor arrnaged in sheets and syncytial pattern.the cells are round to oval with scant cytoplasm with pleomorphic hyperchromatic nuclei. the tumor is cuffed by dense lymphocytic infiltrate. occasional bizarre cells and mitotic activity is noted. invasion into stroma is noted.,biopsy from right breast:invasive carcinoma grade 3modified bloom richardson score is 8 9.tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1714091,carcinoma left breast t4bn2,wedge biopsy ulcer breast.,received multiple grey white skin covered soft tissue bits altogether measures 1.5x1x0.5cm. entire tissue processed.,section shows multiple fragments of tissue showing extensive necrosis and foci of sheets nests and cords of neoplastic tissue. the cells show moderate vacuolated cytoplasm highly pleomorphic nuclei with prominent nucleoli. there is dermal involvement of tumor seen . large area of necrosis seen in the ulcerated areas..,wedge biopsy ulcer breast:suggestive of invasive carcinoma ( nos)modified bloom richardson score is 8 9 grade iiitubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 dermal involvement by tumor seenlarge areas of necrosis noted.
MR1714126,known case of carcinoma left breast,biopsy from left chest wall.,received 6 grey white linear cores measures 1 1.4cm. entire tissue processed.,section shows linear cores of fibrous tissue harboring an infiltrating lesion arranged in cords nests and vague tubules. the cells are ovoid having moderate amount of cytoplasm and hyperchromatic nucleus. mitotic figures are discerned. stroma shows desmoplasia with areas of hemorrhage.,biopsy from left chest wall:invasive carcinoma ( in a known case of carcinoma breast).
MR1714133,left breast lump possibility of carcinoma breast .,biopsy from left breast.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section from breast tissue cores harbours tumor cells arranged in sheets are round with moderate cytoplasm pleomorphic hyperchromatic nuclei. there is invasion into stroma and few areas show necrosis. occasional mitotic activity is noted.,biopsy from left breast:invasive carcinoma grade 2modified bloom richardson score is 7 9.tubule formation : 3nuclear pleomorphic : 2mitotic figures : 2 7 9
MR1714175,left breast mass malignant,biopsy from left breast.,received 5 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section from linear cores of breast parenchyma show tumor arranged in tubules. cells are round to oval with moderate to scant cytoplasm with pleomorphic nucleus and hyperchromatic nuclei . the tumor cells are infiltrating stroma. occasional mitotic activity is noted.,biopsy from left breast:invasive ductal cell carcinoma grade 2modified bloom richardson score is 6 9.tubule formation : 3nuclear pleomorphic : 2mitotic figures : 1 6 9
MR1714176,prostatomegaly possibility of carcinoma breast,prostate core biopsy.,received 8 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section shows tumor cells in fused and poorly formed glands. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,prostate core biopsy :adenocarcinoma(acinar nos). gleason score is 8(4+4) prognostic grade group 4. carcinoma involves 70 of the tissue submitted. lymphovascular invasion is not identified. perineural invasion is not identified.
MR1714191,right breast lump likely carcinoma.,right breast biopsy.,received5 grey whit linear cores measures 0.8 to 1.0cm. entire tissue processed.,section shows linear cores of fibrofatty tissue harboring lesion arranged in sheets cords and nests. the cells have round to irregular hyperchromatic nucleus and moderate cytoplasm. moderate nuclear pleomorphism is noted.,right breast biopsy :infiltrating duct carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1714194,left breast mass.,left breast mass core biopsy.,received single grey white soft tissue bits measures 1 x 1 x 0.5 cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. areas of keratinisation are seen.,left breast mass core biopsy :invasive ductal carcinoma grade 2. modified bloom richard son score is 7(3+2+2).
MR1714199,right breast lump possibility of carcinoma breast.,right breast biopsy.,received 4 grey white to grey brown linear cores measures 1 to 1.2 cm. entire tissue processed.,section from fibroglandular tissue harboring a lesion arranged in cores and nests. the neoplastic cells have round to oval hyperchromatic nucleus and moderate cytoplasm. moderate nuclear pleomorphism noted.,right breast core biopsy :invasive ductal carcinoma grade 2modified bloom richardson score is 7 9.tubule formation :3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1714202,carcinoma left breast multifocal.,biopsy from left breast wide local excision.,received single fibrofatty tissue measures 7x5x2.5cm.section shows lesion relatively well circumscribed grey white tumor which measures 1x0.9x0.8cmdistance from margin: superior margin : 0.2cm.inferior margin : 0.3cm.medial margin : 0.2cmlateral margin : 0.5cmdeep margin : 0.1cmanother lesion measures 0.5x0.5x0.5cm which is 0.8cm away from larger tumor focus.,section from breast shows tumor arranged in sheets and nests. the tumor is having round to oval cells with scant cytoplasm with pleomorphic hyperchromatic nuclei . the tumor is seen invading into stroma and adjacent fat . there are focal areas showing ductal carcinoma in situ component comedo and solid type,biopsy from left breast wide local excision:invasive ductal cell carcinoma grade 2modified bloom richardson score is 6 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 tumor is multifocal .tumor size : 1x0.9x0.8cm( larger focus) 0.5x0.5x0.5cm (smaller focus).high grade ductal carcinoma in situ present ( comedo and solid type)lymphovascular invasion seen.perineural invasion not seen.superior medial and deep margin shows presence of tumor .inferior and lateral margin are free of tumor.
MR1714210,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section shows linear core of tissue harboring a neoplastic lesion arranged in cords a trabeculae and nest . the cells are round to oval with hyperchromatic nuclei and moderate cytoplasm. intervening stroma shows elastosis and lymphocytic infiltrate.,biopsy from left breast:invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9.tubule formation :3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1714231,right breast mass malignant.,right breast biopsy.,received 4 grey white to grey brown linear cores measures 1 to 1.2 cm. entire tissue processed.,section shows linear cores of fibroglandular tissue harboring a neoplasm arranged in sheets cords and nests. the lesional cells have round to irregular hyperchromatic nucleus with moderate cytoplasm.,right breast biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9.tubule formation : 3nuclear pleomorphism :2mitotic figures : 2 7 9 .
MR1714235,right breast lump carcinoma breast,right breast lump biopsy.,received5 grey whit grey brown linear cores measures 0.6 to 1.2cm. entire tissue processed..,section shows tumor cells in diffuse sheets nests cords and tubular. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1714241,case of left breast carcinoma post nact,a) left breast wide excision.b) left axillary dissection.,a) lumpectomy specimen measures 5.5x5.5x3cm skin ellipse measures 4x1cm cut surface grey white lesion measures 2.0x2.0x5cm.b) received fibrofatty mass measures 10x6x3cm largest lymph nodes measures 1.5x1x0.5cm.,a) residual viable tumor presentinvasive ductal carcinoma modified bloom richardson score is 6 9 grade iitubule formation 3 mitotic figures 1 nuclear pleomorphism 2.areas of fibrosis is present surrounding the tumor tumor measures 2.0x2.0x5cm.ductal carcinoma in situ not identifiedlymphovascular invasion not identified.perineural invasion not identifiedresected margins : superior margin: free of tumorinferior margin :free of tumormedial margin :free of tumorlateral margin :free of tumordeep margin :free of tumoraxillary lymph nodes:8 nodes no deposit of tumor.,left breast conservative surgery post nact.residual viable tumor present.maximum dimension of tumor measures 2x2cminvasive ductal carcinoma.ductal carcinoma in situ not identified.lymphovascular invasion not identified.perineural invasion not identified.all resected margins are free of tumor.lymph nodes 8 nodes. no deposit of tumor.pathological stage : ypt1n0..
MR1714313,case of left breast carcinoma.,a) lumpectomy wide excision breast conservative surgery ( frozen specimen ).b) revised deep margin.c) sentinel lymph node( frozen and specimen ).,a) received lumpectomy specimen measures 5x4.5x3.9cm. skin ellipse measures 5.1x0.8cm. cut surface shows an illdefined lesion measures 2.x1x1.8cm.distance from margins :superior : 1.8cm.inferior : 1.1cm.medial : 1.4cm.lateral : 2.4cm.deep : 1.5cm.b) received single fibromuscluar tissue measures 2x2x0.8cm with one surface stitched. entire tissue processed.c) received multiple fibrofatty tissue measures 2.1x2x1cm. largest lymph node measures 1.5x1x1cm. cut surface grey brown.,a) lumpectomy wide excision breast conservative surgery ( frozen specimen ) :tumor bed :shows invasive ductal carcinoma with focal areas of ductal carcinoma in situ is present measures 0.5cm.low grade solid typeinvasive carcinoma is 1.5cm.lymphovascular invasion present.perineural invasion not seen.resected margins :superior : free of tumor.inferior : free of tumor.medial : free of tumor.lateral : free of tumor.deep : free of tumor.b) revised deep margin :shows muscle bundles : free of tumor.c) sentinel lymph node( frozen and specimen ) :one node shows metastatic of tumor is the subcapsular space out of 3 nodes ( further paraffin slide ).perinodal spread not present.,breast conservative surgery wide excision:maximum dimension of tumor is 2cm.invasive ductal carcinoma measures 1.5cm.ductal carcinoma in situ low grade solid type is measures 0.5cm.lymphovascular invasion present.perineural invasion present.all resected margins are free of tumor.revised deep resected margin is free of tumor.lymph nodes :one node shows metastatic deposits of tumor out of 13 nodes ( deposits present with paraffin section ).perinodal spread not present.stage : pt1n1.
MR1714343,right breast mass malignant.,right breast core biopsy.,received 5 grey white linear cores measures 0.8 to 1.0 cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 7(3+2+2).
MR1714357,left breast lump possibility of carcinoma breast.,left breast core biopsy.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1714377,known case of carcinoma left breast ( post nact),a) left bcsb) axillary clearance,a) lumpectomy specimen 9.5x6x5cm2 skin flaps noted 1st measures 5x1.5cm2nd measures 6x1cm. no obvious lesion identified. however soft firm greyish white area fibrosis seen at a distance from margins:superior margin: 2cminferior margin : 3cmmedial margin : 1cmlateral margin : 5cmdeep margin : 3cmb) received fibrofatty tissue measures 8x4x2cm largest lymph node measures 1x0.8x0.6cm cut surface fatty infiltration.,a) section shows breast parenchyma harboring an infiltrating neoplasm arranged as cords small nests poorly formed glandular structures composed of cells exhibiting increased n c ratio pleomorphic hyperchromatic nuclei occasional conspicuous nucleoli and scanty cytoplasm. the intervening stroma shows dense fibrocollagenous connective tissue infiltrated by lymphoid aggregates . all resected margins ( superior inferior medial lateral and deep ) are free of tumor. one intramammary lymph node identified free of tumorthe overlying skin is free of tumor.b) 22 lymph nodes identified : free of tumor (0 22),a) left bcs:invasive carcinoma breast nst grade iimodified bloom richardson score 6 9.tubule formation 3nuclear pleomorphism 2mitotic activity 1tumor measures 0.8cm in greatest dimension no evidence of ductal carcinoma in situlymphovascular emboli not identifiedperineural invasion not identified.all resected margins are free of tumor skin is free of tumor.b) axillary clearance:22 lymph nodes identified are free of tumor ( 0 22)
MR1714399,left breast lump possibility of carcinoma breast .,biopsy from left breast.,received 6 grey white to grey brown linear cores measures 0.6 to 1.4cm. entire tissue processed.,sections show cores of breast tissue with an invasive neoplasm in sheets and nests showing moderate eosinophilic cytoplasm moderate nuclear pleomorphism and hyperchromatism. prominent nucleoli and increased mitosis seen. extensive peri tumoral inflammation noted.,biopsy from left breast:suggestive of invasive carcinoma ductal (nos)modified bloom richardson score is 8 9 grade iii.tubule formation :3nuclear pleomorphism : 2mitotic activity : 3 8 9
MR1714422,left breast lump malignant,biopsy from left breast.,received multiple fragmented grey white linear cores measures 0.6 to 1.2cm. entire tissue processed.,section shows cores of breast tissue with foci of ductalcarcinoma in situ (solid type) and suspicious foci of invasive carcinoma in nests and sheets. the cells show moderate cytoplasm pleomorphic hyperchromatic nuclei and prominent nucleoli. increased mitosis seen.,biopsy from left breast:ductal cell carcinoma in situ with suspicious foci of invasionsuggest repeat biopsy.as the material submitted show large areas of desmoplasia and scanty epithelial elements.
MR1714482,right breast lump possibility of carcinoma breast .,biopsy from right breast.,received 6 grey white to grey brown linear cores measures 0.6 to 1.2cm. entire tissue processed.,section shows cores of breast tissue with an invasive neoplasm in nests and glands. the cells show moderate eosinophilic to clear cytoplasm moderate nuclear pleomorphism and hyperchromatism with prominent nucleoli. adjacent ductal carcinoma in situ (comedo type) noted. scattered peritumoral inflammation seen.,biopsy from right breast:suggestive of invasive carcinoma ductal (nos)modified bloom richardson score is 6 9 grade ii.tubule formation :2nuclear pleomorphism : 2mitotic activity : 2 6 9
MR1714494,left breast lump p o carcinoma breast.,biopsy from left breast.,received multiple grey white linear cores measures 0.8 to 1cm. entire tissue processed.,sections from breast harbor tumor arranged in sheets and tubules. the tumor is having round to oval cells with moderate cytoplasm with pleomorphic hyperchromatic nuclei. the tumor is seen invading stroma and fat. component of ductal carcinoma in situ (comedo) pattern is seen. the intervening stroma is hyalinized.,biopsy from left breast:invasive ductal carcinoma grade ii.modified bloom richardson score is 6 9tubular formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1714514,carcinoma right breast post nact.,a. right sentinel nodes.b) right breast right modified radical mastectomy(post nact).,a) fibrofatty tissue measures 4.5x4x1.5 cmlargest lymph node measures 2x1x0.4 cm cut surface show dye noted.b) procedure : modified radical mastectomylaterality : right breast.total dimensions :medial lateral : 23 cm superficial deep: 6 cm superior inferior : 21 cmskin ellipse : 16x10 cmnipple : normalscar surgical defect : not seentumor : singletumor size : 4.5 x 4 x 2 cmlocation of tumor : upper outer quadrantmargins of tumor : ill defineddeep margin : 2 cmmuscle : absentadjacent breast : fibrofatty tissueaxillary tail : 6.5x5x2 cmsize of largest node : 1.5x1x0.5 cm cut surface shows grey white.,section from breast shows an invasive lesion arranged in islands nests and cords consisting of neoplastic cells having round to oval pleomorphic vesicular nuclei prominent nucleoli and moderate amount of clear cytoplasm. mitotic figure is 7 10 hpf. extensive ductal carcinoma in situ seen solid and comedonecrosis type. stroma shows plasmacytic infiltrates and areas of hyalinisation and necrosis.,a) right sentinel nodes: five lymph nodes identified all are free of tumor(0 5).b) right breast right modified radical mastectomy(post nact) :residual invasive ductal carcinoma grade 2 modified bloom richardson score is 7( 3+2+2). tumor measures 4.5 cm in greatest dimension and is located in the upper outer quadrant. ductal carcinoma in situ of solid and comedo pattern with intermediate nuclear grade is seen. lymphovascular invasion is not defined. perineural invasion is not defined. posterior resection margin is free of tumor. nipple and areola are unremarkable.lymph nodes: seventeen lymph nodes are identified negative for malignancy(0 17).
MR1714555,right breast lump.,right breast biopsy.,received fragmented multiple grey white linear cores measures 0.2 to 0.7cm. entire tissue processed.,sections from breast parenchyma shows fragments of tissue with and collagenous stroma. there are scattered clusters of dysplastic oval cells with oval hyperchromatic nuclei and moderate cytoplasm.,right breast biopsy:scattered clusters of neoplastic cells favor ductal carcinoma.however tissue is too sparse for appropriate grading.
MR1714558,known case of carcinoma right breast.,biopsy from left breast lump.,received 5 grey white linear cores measuring 1 to 1.2 cm. entire tissue processed.,section shows multiple fragments of breast parenchyma with a infiltrating lesion arranged in sheets vague glandular pattern. the cells forming the lesion are round to oval with hyperchromatic nuclei and scant to moderate cytoplasm. mitosis 4 5 10 hpf. inflammatory infiltrate composed. lymphocytes neutrophils.,biopsy from left breast lump :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1714593,left breast carcinoma.,biopsy from left breast lump.,received 4 greywhite linear cores measuring 0.7 to 1cm. entire tissue processed.,section shows multiple cores of fibrocollagenous tissue with an infiltrative neoplasm in nests and glands. the cells show moderate clear to eosinophilic cytoplasm increased n:c ratio pleomorphic hyperchromatic nuclei. many mitotic figures noted.,biopsy from left breast:invasive carcinoma ductal type (nos).mbr score 8 grade 3.tubule formation : 2nuclear pleomorphism : 3mitotic figures : 3 8 9
MR1714665,left breast lump possibility of carcinoma breast.,left breast lump core biopsy.,received 5 grey white linear cores measures 1.2 to 1.6 cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1714671,left breast lump possibility of carcinoma breast.,biopsy from left breast .,received 4 grey white linear cores measures 1 to 1.3cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged in irregular islands and sheets. the cells are moderately pleomorphic large nest of cells showing abundant cytoplasm. occasional bizarre nuclei seen. stroma is desmoplastic. areas of necrosis noted. mitotic figures discerned.,left breast core biopsy:invasive carcinoma grade 3.modified bloom richardson score is 8 9 tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1714674,lump left breast since 1 month.,a) left axillary sentinel nodes.b) total mastectomy.c) left sentinel lymph node biopsy.,a) received fibrofatty tissue measures 2x1x0.8cm. 4 lymph nodes identified. cut surface grey white fatty infiltrated.b) received in : formalinprocedure : mastectomy.laterality : left.total dimensions : medial to lateral : 18m. superficial to deep : 5cm. superior to inferior : 16cmskin ellipse :11x7.5cm.nipple :normal scar surgical defect :not seen.tumor : single.tumor size : 3.2x3.2x2.5cm.location of tumor : upper outer quadrant.deep margin : 1cm.muscle : absent adjacent breast : fibrofatty tissue. total number of nodes : sentinel lymph node : 4nodes. :mastectomy,3 nodes.c) received fibrofatty tissue measures 3x2x1cm. one lymph node measures 0.6x0.5x0.4cm fatty infiltration.,left breast left modified radical mastectomy:invasive ductal carcinoma grade ii.modified br score : 6 9.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2tumor measures 3.2cm in greatest dimension and is located in the upper outer quadrant.ductal carcinoma in situ not identified.lymphovascular invasion not present.perineural invasion not present.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: sentinel node : 4nodes no deposits of tumor.mastectomy specimen node 3 nodes no deposits of tumor.specimen c : 1 node shows no deposits of tumorsummary : left breast left modified radical mastectomy:invasive ductal carcinoma grade ii.nodal metastases : sentinel lymph node 4 nodes no deposits of tumor.mastectomy 3 nodes no deposits of tumor.specimen c : 1 node no deposits of tumorpathological stage :ypt2n0.
MR1714688,left breast lump birads ivc lesion.,biopsy from left breast lump,received 4 grey white to grey brown linear cores measures 0.4 to 1.4cm. entire tissue processed.,section show cores of breast tissue with invasive neoplasm in glandular and cribriform architecture with cyst like areas showing eosinophilic material . the cells show moderate nuclear pleomorphism and hyperchromatic. mitosis is increased. ductal cell carcinoma in situ cribriform and solid type noted.,biopsy from left breast lump:invasive carcinoma with cribriform features.modified bloom richardson score is 6 9 grade 2tubule formation :2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1714690,right breast lump carcinoma breast.,right breast lump biopsy.,received 5 grey white to grey brown linear cores measures 0.5 to 1.5 cm. entire tissue processed.,section show multiple linear cores with an infiltrative neoplasm arranged in glands small nests and cords. the tumor cells show mild to moderate pleomorphism with round to oval nuclei fine chromatin inconspicuous to small nucleoli and scant to moderate amount of eosinophilic to vacuolated cytoplasm.,right breast lump core biopsy :invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1714699,left breast lump possibility of carcinoma breast,biopsy from left breast.,received 4 grey white soft tissue bits measures 0.4 to 1.2cm. entire tissue processed.,section shows breast parenchyma harboring infiltrating lesion arranged in tubules. the lesional cells are round to oval cells have hyperchromatic nuclei and moderate cytoplasm. stroma shows desmoplasia. mitosis 3 4 10hpf.,biopsy from left breast :invasive ductal carcinoma grade 2modified bloom richardson score is 6 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1714701,left breast lump possibility of carcinoma breast.,biopsy from left breast .,received 7 grey white linear cores measures 0.2 to 1cm. entire tissue processed.,section sows linear cores of tissue harboring an infiltrating lesion arranged in vague nest and sheets. the cells have round to oval hyperchromatic nuclei inconspicuous nucleoli and moderate amount of cytoplasm. stroma shows desmoplasia. mitotic figures discerned.,left breast core biopsy:poorly differentiated malignancy.
MR1714706,right axillary tail breast mass possibility of carcinoma breast.,biopsy from right axillary tail breast mass.,received 4 grey white soft tissue bits measures 1 to 1.5cm. entire tissue processed.,section shows fibrous tissue harboring infiltrating lesion arranged in tubules cores and nests. the lesional cells are round to oval with hyperchromatic nuclei and prominent nucleoli in few and scant cytoplasm. stroma shows hyalinisation lymphocytic infiltrate. areas of necrosis noted. mitosis 6 8 10hpf.,biopsy from right axillary tail breast mass:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1714717,left breast lump possibility of carcinoma breast.,biopsy from left breast,received 4grey white linear cores measures 0.5 to 1.2cm. entire tissue processed.,section shows fibro adipose tissue with an invasive neoplasm in sheets and nests. the cells are polygonal with moderate eosinophilic to clear cytoplasm. moderate nuclear pleomorphism and hyperchromatic with prominent nucleoli seen. extensive free tumoral inflammation noted.,biopsy from left breast:invasive carcinoma ductal type nstmodified bloom richardson score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1714751,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received 5 grey white to grey linear cores measures 0.8 to 1cm. entire tissue processed.,section shows cores of breast parenchyma with a lesion arranged in sheets tubules and cores . cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm. large areas of necrosis noted. mitotic figures discerned.,biopsy from left breast:invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9(3+2+1)
MR1714756,right breast lesion birads lib.,biopsy from right breast lesion.,received 6 grey white to grey yellow linear cores measures 0.5 to 1.2cm. entire tissue processed.,section shows cores of breast tissue with an invasive neoplasm composed of cells in sheets trabecular and glandular pattern. the cells show moderate eosinophilic cytoplasm moderate nuclear pleomorphism with hyperchromatism and increased mitosis.,biopsy from right breast lesioninvasive ductal carcinoma ( nos):modified bloom richardson score is 7 9 grade 2tubule formation :2nuclear pleomorphism : 3mitotic figures : 2 7 9
MR1714775,right breast mass carcinoma.,biopsy form right breast.,received multiple grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows linear cores of tissue harboring an infiltrating lesion arranged in sheets having pleomorphic round to oval hyperchromatic nuclei and moderate amount of cytoplasm. intermixed lymphoplasmacytic infiltrate noted. stroma show desmoplasia . areas of necrosis noted. mitotic figures discerned.,biopsy form right breast:invasive carcinoma no special type grade ii.modified bloom richardson score is 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1714792,right breast lump malignant.,biopsy from right right breast.,received 6 grey white linear cores measures 0.8 to 1.2cm. entire tissue processed.,section shows linear cores harboring an infiltrating lesion arranged predominantly in glandular pattern focal nests and sheets. few glands show micropapillae comedo necrosis and cribriform appearance . the individual cells show increased nucleo cytoplasmic ratio nuclear hyperchromasia pleomorphism and variable amount of eosinophilic cytoplasm. the intervening stroma is dense fibrocollagenous and shows infiltration by lymphocytic and few plasma cells. foci of ductal carcinoma in situ with comedonecrosis seen.,biopsy from right right breast:invasive carcinoma grade iimodified bloom richardson score is 6 9 tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 ductal carcinoma in situ with comedonecrosis seen.
MR1714804,known case of carcinoma breast on follow up,lung biopsy.,received four grey white to grey black linear core measures 0.4 to 0.6cm. entire tissue processed.,section show multiple linear cores with an infiltrating neoplasm arranged in the form of glands. the neoplastic cyt are lined by columnar epithelium with round to oval nuclei inconspicuous to small nucleoli and moderate amount of eosinophilic cytoplasm. the surrounding stroma shows fibrosis and focal anthroastic pigment dissection.,lung biopsy :adenocarcinoma. primary. metastatic.
MR1714821,right breast mass malignant.,biopsy from right breast mass.,received multiple grey white linear cores measures 0.6 to 0.8cm. entire tissue processed,sections shows linear tissue cores harboring an infiltrative lesion arranged in sheets nests trabecular focal glandular and individual cells pattern. the neoplastic cells show increased nucleo cytoplasmic ratio nuclear hyperchromasia pleomorphism and scant cytoplasm. there is presence of dense fibrocollagenous connective tissue infiltrated by lymphocytic infiltrative. areas of hemorrhage necrosis and congested blood vessels are noted.,biopsy from right breast mass:invasive carcinoma grade 2.modified bloom richardson score 7 9.tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1714824,right breast lump p o carcinoma breast.,biopsy from right breast lump.,received multiple grey white linear cores measures 0.8 to 1.2cm. entire tissue processed.,sections show linear tissue cores harboring an infiltrative lesion arranged in nests sheets and focal glandular pattern. the individual tumor cells show increased nucleo cytoplasmic ratio nuclear hyperchromasia occasional prominent nucleoli and pale eosinophilic cytoplasm. intervening stroma is composed of dense fibrocollaginous connective tissue adipose tissue infiltrated by lymphocytic infiltrate.,biopsy from right breast lump:invasive ductal carcinoma grade ii.modified bloom richardson score is 6 9.tubular formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1714826,right breast lump carcinoma breast.,biopsy from right breast.,received 4 grey white linear measures 0.8 to 1.3cm in length. entire tissue processed. 0.2cm thickness.,section shows linear tissue cores harboring an infiltrating lesion arranged in cords trabecular and few small nests . the individual tumor cells show increased nucleo cytoplasmic ratio pleomorphic hyperchromatic nuclei and focal nucleoli are noted. the intervening stroma dense fibrocollagenous and is infiltrated by lymphocytes..,biopsy from right breast:modified bloom richardson score is 7 9 grade 2tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1714866,right breast mass malignant.,biopsy fro right breast.,received multiple grey white linear cores measures 0.5 to 2cm. entire tissue processed.,section shows cores of breast tissue with an invasive neoplasm composed of cells in sheets and nests. the cells shows moderate eosinophilic to clear cytoplasm. moderate nuclear pleomorphism and hyperchromatism. increase mitotic figures noted stroma is desmoplastic.,biopsy fro right breast:invasive carcinoma ductal type nos grade ii.modified bloom richardson score is 7 9tubular formation 2nuclear pleomorphism 2mitotic figures 3 7 9
MR1714889,right breast lump,biopsy from right breast.,received 4 grey white to grey yellow linear cores measures 0.3 to 0.7cm. entire tissue processed.,section shows cores of breast tissue with an invasive neoplasm in nests and glands. the cells have increased n c ratio hyperchromatic nuclei with moderate nuclear pleomorphism. stroma is desmoplastic . ductal carcinoma in situ solid and comedo type present. peritumoral inflammatory cell infiltrate also seen.,biopsy from right breast:invasive carcinoma ductal type.modified bloom richardson score is 6 9 grade 2tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9note: scant volume of tumor present.tissue may not be adequate for ihc.
MR1714907,left breast lump.,biopsy from left breast.,received multiple grey white to grey yellow linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of fibroadipose tissue with an invasive neoplasm composed of sheets trabeculae and nests of cells. the cells show moderate nuclear pleomorphism and hyperchromatism. mitosis is increased. stromal desmoplasia present. intratumoral lymphocytic infiltration noted.,biopsy from left breast:invasive ductal carcinoma nos grade ii.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2 mitotic figures 2 7 9
MR1714912,right breast lump possibility of carcinoma breast.,right breast core biopsy.,received five grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets nests and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1714931,left breast lump possibility of carcinoma breast.,left breast lump core biopsy.,received multiple grey white soft tissue bits altogether measures 0.6 x 0.5 x 0.3 cm. entire tissue processed.,section shows tumor cells in tubules and sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 1 modified bloom richardson score is 5(2+2+1).
MR1714932,left breast lump malignancy.,biopsy from left breast lump.,received multiple grey white to grey brown linear cores measures 0.6 to 1.2cm. entire tissue processed.,section shows cores of breast tissue with an invasive neoplasm in nests and trabecular. the cells show increased n:c ratio moderate nuclear pleomorphism and hyperchromatism prominent nucleoli with increased mitosis.,biopsy from left breast lump:invasive ductal carcinoma grade ii.modified bloom richardson score is 7 9tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1714933,right breast mass malignant,biopsy from right breast.,received 5 grey white to grey brown linear cores measures 0.5 to 0.8. entire tissue processed.,section shows cores of breast parenchyma harboring a lesion arranged in sheets nests and cords. cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm. adjacent stroma shows desmoplasia and areas of hemorrhage. karyorrhectic debris noted.,biopsy from right breast mass biopsy:invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9(3+2+2).
MR1714969,right breast lump malignancy.,right breast lump core biopsy.,received multiple grey white linear cores measures 0.6 to 0.8cm. entire tissue processed.,section show linear cores of breast parenchyma with ducts showing cells arranged in complex branching pattern with irregular sieve like spaces. . the cells have round to oval bland nuclei. few cells show apocrine change. stroma show hyalinisation.occasional foci shows infiltrating tubules and cords with hyperchromatic nuclei and scant to moderate amount of cytoplasm.,right breast lump core biopsy:suggestive of invasive carcinoma( no specific type) with cribriform dcis pattern seenmbr score 6 9
MR1715019,left breast lump p o carcinoma breast.,left breast biopsy.,received 3 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in tubules nests and cords. the cells are ovoid having moderate amount of pale eosinophilic cytoplasm hyperchromatic pleomorphic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma shows desmoplasia with areas of hemorrhage and focal areas of necrosis.,left breast biopsy:invasive carcinoma nos grade 2tubular formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR1715025,left breast lump p o carcinoma breast.,biopsy from left breast lump.,received multiple grey white to grey yellow linear cores measures 0.5 to 0.8cm. entire tissue processed.,section cores of breast tissue with extensive necrosis and attempted granulomas and lymphocytic infiltration. no evidence of atypia or increased mitoses noted. adjacent breast show hyperplastic ducts.,biopsy from left breast lump:suggestive of granulomatous mastitis with necrosis.no evidence of malignancy in the smears studied.suggest repeat biopsy if clinically radiologically warranted..
MR1715046,right breast lump malignant.,right breast lump biopsy.,received multiple grey white to linear cores measures 0.6 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in tubules nests and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nuclei. mitotic figures are discerned. stroma shows desmoplasia with lymphomononuclear infiltrates. areas of hemorrhage and necrosis are seen. ductal carcinoma in situ solid and comedonecrosis pattern noted.,right breast lump biopsy:invasive carcinoma nos grade 2tubular formation 2nuclear pleomorphism 2mitotic figures 2 6 9 ductal carcinoma in situ solid and comedonecrosis pattern seen.
MR1715062,right breast lump.,biopsy from right breast lump.,received multiple grey white linear cores measures 1 to 1.4cm. entire tissue processed.,section shows cores of breast parenchyma and a fragment of skin. breast tissue harbors a lesion arranged in aggregate cords and singly dispersed cells. the neoplastic cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm. mitosis noted. adjacent few glands are dilated and show hyperplasia. stroma shows fibrosis.,biopsy from right breast lump:suggestive of invasive carcinoma grade 2modified bloom richardson score 6 9.tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1715111,left breast incision biopsy.,biopsy from left breast,received single grey white soft tissue bits measures 0.4x0.3x0.3cm. entire tissue processed.,section shows skin with underlying invasive neoplasm in predominating glands nests in cell shows mild nuclei plemorphism and hyperchromatism. few show prominent nucleoli mild nuclear pleomorphism .perineural invasion noted .foci show cribriform pattern. dermal involvement present. adjacent parenchyma shows lymphocytic infiltrate.mitosis 3 4 10hpf.,biopsy from left breast:invasive ductal carcinoma.modified bloom richardson score is 6 9 grade 2tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1715114,carcinoma breast.,left breast core biopsy.,received 4 grey white linear cores measures 1 to 1.5 cm. entire tissue processed.,section shows cores of breast tumor cells with lymphocytes plasma cells epitheloid cells and few multivacuolated giant cells. no atypical cells are seen.,left breast core biopsy :features are suggestive of granulomatous inflammation.no evidence of malignancy is seen in the tissue submitted.
MR1715122,carcinoma breast.,left breast mass core biopsy.,received 5 grey white to grey brown linear cores measures 1 to 1.2 cm. entire tissue processed.,section shows few ductules lined by columnar epithelium. stroma shows spindle cells. no atypical cells is seen.,left breast mass core biopsy :shows features of benign proliferative breast disease. no definite evidence of malignancy is seen.suggest repeat biopsy excision of the lump for further confirmation.
MR1715128,known case of carcinoma right breast post lumpectomy.,biopsy from right breast lesion.,received multiple grey white linear cores measures 0.5 to 0.8cm. entire tissue processed.,section shows linear tissue cores of breast tissue with infiltrative lesion arranged as cords and individually dispersed atypical cells showing increased nucleo cytoplasmic ratio and slight hyperchromasia. few thick walled blood vessels also noted.,biopsy from right breast lesion:invasive carcinoma grade 2modified bloom richardson score is 6 9.tubuleformation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1715147,left breast lump neoplastic.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.8 to 1.2cm. entire tissue processed.,section from the breast parenchyma shows a infiltrative neoplasm arranged in sheets glands and vague lobules. the cells forming the lesion are round to oval with hyperchromatic nuclei and abundant eosinophilic cytoplasm. adjacent stroma shows inflammatory infiltrates composed at lymphocytes. mitosis 5 6 10hpf.,biopsy from left breast lump :invasive ductal carcinoma grade 2 modified bloom richardson score 7(3+2+2).
MR1715177,left breast lump.,left breast lump biopsy.,received 4 linear cores measures 1 to 1.5 cm. entire tissue processed.,section studied shows linear cores of breast parenchyma showing ductal carcinoma in situ solid cribriform and papillary pattern with round cells moderate eosinophilic cytoplasm intermediate nuclear grade. stroma shows hyalinisation.,left breast lump biopsy. shows features of ductal carcinoma in situ of solid and cribriform pattern with intermediate nuclear grade.
MR1715186,left breast mass malignant.,biopsy from left breast mass.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of fibrocollagenous tissue with an invasive neoplasm predominantly in sheets nests and glands. the cells show moderate cellular atypia eosinophilic to clear cytoplasm and pleomorphic hyperchromatic nuclei. extensive peritumoral eosinophilic infiltration noted. stroma is desmoplastic.,biopsy from left breast mass.invasive carcinoma ductal type (nos) grade ii.modified bloom richardson score is 6 9.tubular formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR1715217,lump in left breast malignant.,biopsy from left breast.,received multiple grey white linear cores measures 0.5 to 1.2cm. entire tissue processed.,section shows cores of tissue with an invasive neoplasm composed of sheets and nests of cells with moderate eosinophilic to clear cytoplasm moderate nuclear pleomorphism hyperchromatism with prominent nucleoli and increased mitosis infiltration into fat noted. stroma appears dismoplastic.,biopsy from left breast:invasive carcinoma ductal type nos grade iii.modified bloom richardson score 8 9.tubular formation 3nuclear pleomorphism 2mitotic figures 3 8 9
MR1715238,left breast mass malignant.,biopsy from left breast.,received multiple grey white to grey yellow linear cores measures 0.5 to 1cm. entire tissue processed.,section show multiple cores of breast tissue showing extensive ductal carcinoma in situ features. solid type and comodo necrosis. few foci specious of invasion noted with cells infiltrating into fat. the cells show abundant to moderate eosinophilic cytoplasm moderate nuclear pleomorphism with hyperchromatism and prominent nucleoli atypical mitotic figures noted.,biopsy from left breast:extensive comodo and solid type ductal carcinoma in situ.nuclear grade iii with suspicious foci of invasion.suggest repeat biopsy to look for invasion and for ancillary studies.
MR1715240,right breast.,right breast core biopsy.,received multiple grey white to grey yellow linear cores measures 0.2 to 0.5 cm. entire tissue processed.,section shows tumor cells in nests cords and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1715242,left breast lump.,biopsy from left breast lump,received 3 grey white linear cores measures 0.5 to 0.7cm. entire tissue processed.,section show linear cores of tissue with an infiltrating lesion arranged in nests tubules . the cells have round to oval moderately pleomorphic hyperchromatic nuclei with moderate amount of cytoplasm. stroma show desmoplasia . areas of calcification and necrosis noted. fotal areas show few multinucleated foreign body giant cells. mitotic figures discerned.,biopsy from left breast lump:invasive carcinoma nuclear grade iimodified bloom richardson score is ( 3+2+1)6.
MR1715263,left breast lump p o carcinoma breast.,biopsy from left breast.,received multiple grey white to grey brown linear cores measures 0.4 to 1cm. entire tissue processed.,section shows cores of breast tissue with an invasive neoplasm in sheets and nests the cells show moderate eosinophilic to clear cytoplasm moderate nuclear atypia with hyperchromatism. stroma appears desmoplastic infiltration into fat noted.,biopsy from left breast:invasive carcinoma ductal type (nos) grade ii.modified bloom richardson score is 6 9.tubular formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1715276,right breast solid cystic masscarcinoma breast.,biopsy from right breast.,received 4 grey white to grey yellow linear cores measures 0.5 to 0.7cm. entire tissue processed.,section show linear cores of breast parenchyma with lesion arranged in sheets having harboring plasmacytic round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma show dense lymphoplasmacytic infiltrate . intermixed dilated blood vessels seen. mitotic figures discerned.,biopsy from right breast:invasive carcinoma grade iiimodified bloom richardson score is (3+3+2)8.
MR1715283,left breast lump malignancy,biopsy from left breast,received 6 grey white to grey yellow linear cores altogether measures 1 to 1.2cm. entire tissue processed.,section show linear cores of tissue harboring a neoplastic lesion arranged in sheets cords with cells having pleomorphic round to oval hyperchromatic nuclei and moderate amount of cytoplasm .stroma show desmoplasia. mitotic figures noted.,biopsy from left breast:invasive ductal carcinoma. grade iiimodified bloom richardson score is (3+2+3)8.
MR1715315,left breast fungating mass.carcinoma breast.,left breast core biopsy.,received 3 grey white linear cores measures 1.2 to 1.5cm. entire tissue processed.,section shows cores of tissue harboring an infiltrating lesion in sheets with cells background to oval moderate pleomorphic hyperchromatic nuclei inconspicious nucleoli and moderate amount od cytoplasm. stroma show desmoplasia mitotic figures discsrned.,left breast core biopsy:invasvie ductal carcinoma grade ii.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1715322,right breast lump.,biopsy from right breast.,received multiple grey white to grey brown linear cores measures 0.2 to 0.4cm. entire tissue processed.,section show cores of breast tissue with invasive neoplasm composed of cells in nests glands sheets and cords. the cells show moderate nuclear pleomorphism with increased mitotic figures. adjacent dactal carcinoma in situ cribriform and solid type.,biopsy from right breast:invasive ductal carcinoma nos grade ii.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1715323,right breast mass.carcinoma breast.,right breast core biopsy.,received multiple grey white to grey yellow linear cores measures 0.5 to 1 cm. entire tissue processed.,section shows tumor cells in nests and sheets lying in extracellular pools of mucin. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy:suggestive of mucinous carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1715332,right breast mass.,right breast core biopsy.,received multiple grey white to grey brown linear cores measures 0.5 to 1.2 cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1715357,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 6 grey white linear cores measures 0.3 to 1cm. entire tissue processed.,section shows linear cores of tissue with a lesion arranged in nest cords and sheets. the cells have round to oval hyperchromatic nuclei inconspicious nucleoli and moderate amount of cytoplasm. stroma shows desmoplasia . mitotic figures discerned.,biopsy from left breast lump:invasive carcinoma grade ii.modified bloom richardson score is (3+2+1)6.
MR1715360,left breast lump p o carcinoma breast.,right breast lump biopsy.,received multiple grey white linear cores measures 0.2 to 0.4cm. entire tissue processed.,sections show linear to fragmented tissue cores showing a lesion arranged in sheets. the individual tumor cells show increased nucleo cytoplasmic ratio hyperchromatic and pleomorphic nuclei and inconspicuous nucleoli. there is dense fibrocollagenous connective tissue infiltrated by lymphocytes plasma cells and few eosinophils.,right breast lump biopsy:invasive ducal carcinoma nos grade 2modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1715368,left breast lump malignant.,trucut biopsy left breast lump.,received multiple grey white to grey yellow linear cores measures 0.2 to 1cm. entire tissue processed.,section shows 4 linear cores of fibroglandular tissue harboring an infiltrating lesion arranged in sheets tubular and cords. the lesional cells have moderate cytoplasm pleomorphic round to irregular hyperchromatic nucleus and inconspicuous nucleoli. mitotic figures discerned.,trucut biopsy left breast lump.invasive ductal carcinoma grade ii.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1715370,left breast lump malignant.,biopsy form left breast lump.,received multiple grey white to grey yellow linear cores measures 0.6 to 1.0cm. entire tissue processed.,section shows cores of breast tissue with an infiltrating neoplasm composed of cells in sheets and nests.. the cells show moderate nuclear pleomorphism hyperchromatism and prominent nucleoli. extensive ductal carcinoma in situ cribriform and solid type noted.,biopsy form left breast lump:invasive ductal carcinoma nos with ductal carcinoma in situ grade 2modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic activity 2 7 9 extensive ductal carcinoma in situ cribriform and solid type.foci of necrosis seen.
MR1715406,right breast mass.carcinoma breast.,biopsy from right breast mass.,received multiple grey white to grey yellow linear cores measures 0.5 to 1.2cm. entire tissue processed.,section shows 5 linear cores of fibrocollagenous tissue of which 4 linear cores shows are infiltrating lesion arranged in cords nests and tubules. the lesional cells have moderate cytoplasm pleomorphic irregular hyperchromatic nucleus.,biopsy from right breast mass:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9.tubular formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR1715431,left lung mass carcinoma lung.,biopsy from left lung mass.,received 6 greywhite to greybrown linear cores measuring 0.5 to 1.2cm. entire tissue processed.,section shows multiple cores of lung parenchyma with a neoplasm arranged in solid nests and islands. the tumor cells show moderate nuclear pleomorphism with round to oval hyperchromatic nuclei moderate amount of eosinophilic to vacuolated cytoplasm. few nests of tumor cells are seen in background of abundant extracellular mucin. foci of necrosis are seen with peripheral arrangement of tumor cell nests around necrotic foci.,biopsy from left lung mass:feature favor mucinous adenocarcinoma. primary in lung.however ihc suggested to rule out possibility of metastasis from breast.
MR1715435,carcinoma right breast t1n1.,a) wide excision lump.b)axillary clearance.,a) received skin covered fibrofatty tissue mass measures skin measures 2.1x1.5cm. unremarkable. cut surface shows single grey white firm lesion measures 1.5x1.3x1.1cm.as is located at a distance of following from resected margins:deep margin : 1.5cm.medial margin : 1cm.lateral : 1.5cm.superior : 1cm.inferior : 1.5cm.b) received fibrofatty tissue measures 3x2x1cm. 6 lymph nodes identified largest lymph node measures 1x0.7x0.5cm. cut surface unremarkable.,right breast conservative surgery :tumor bed : invasive ductal carcinoma.maximum dimension of tumor 1.5cm.invasive carcinoma is 1cm.ductal carcinoma in situ cribriform and comedonecrosis measures 0.5cm.modified br score is 7 9 grade ii.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 nuclear grade ii.lymphovascular invasion present.perineural invasion not present.resected margin :superior margin : free of tumor.inferior margins : free of tumor.medial margins : free of tumor.lateral margins : free of tumor.deep margins : free of tumor.axillary lymph node : two nodes show metastatic deposits of tumor out of 10 nodes.perinodal spread is present.,breast conservative surgery :invasive ductal carcinoma.maximum dimension of tumor 1.5cm.invasive carcinoma is 1cm.ductal carcinoma in situ is cribriform and comedonecrosis is 0.5cm.nuclear grade ii.lymphovascular invasion is present.perineural invasion not present.all resected margins are free of tumor.pathological grade : pt1n1.
MR1715475,right axillary tail mas possibility of primary malignant breast mass..,biopsy from right axillary node.,received 3 linear cores 0.8 to 0.9cm. entire tissue processed.,section shows cores of fibrocollagenous tissue with an invasive neoplasm in cords and singly scattered cells showing marked nuclear pleomorphism hyperchromasia with moderate eosinophilic to clear cytoplasm. fat infiltration and perineural invasion noted.,biopsy from right axillary node:invasive ductal carcinoma (nos) grade 3modified bloom richardson score is (3+3+2) 8 9
MR1715476,right breast mass malignant.,trucut biopsy right breast mass.,received multiple grey white to grey yellow linear cores measures 0.8 to 1.2cm. entire tissue processed.,section shows 4 linear cores of fibroglandular tissue harboring an infiltrating lesion with foci of comedo necrosis. the lesional cells are arranged in nests and sheets having pleomorphic round to irregular hyperchromatic nucleus few with prominent nucleoli and moderate cytoplasm. dense lymphocytic infiltrate noted.,trucut biopsy right breast mass:invasive ductal carcinoma grade 2 ductal carcinoma in situ (cribriform and solid type) notedmodified bloom richardson score is 6 9.tubular formation 3nuclear pleomorphism 2mitotic activity 1 6 9
MR1715490,known case of carcinoma left breast post op.left breast lesion.,left breast biopsy.,received multiple grey white to grey brown linear cores measures 0.4 to 0.6cm. entire tissue processed.,section shows cores of fibroadopose tissue with an invasive neoplasm in papillary pattern with thick fibrovascular cores. the cells show eosinophilic cytoplasm moderate nuclear pleomorphism and hyperchromatic stroma shows desmoplasia hyalinization and calcification.,left breast biopsy :invasive papillary carcinoma .
MR1715585,right breast mass malignancy.,right breast mass.,received multiple grey white linear cores measures 0.5 x 0.7 cm. entire tissue processed.,section show multiple fragment of breast parenchyma with infiltrative neoplasm arranged in sheets nests and vague glandular pattern. the cells are round to oval hyperchromatic nuclei abundant eosinophilic cytoplasm. inflammatory infiltrative composed of lymphoplasmacytic and multinucleated giant cells. mitosis 5 6 10hpf.,right breast mass biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1715605,left breast lump.,biopsy from left breast lump.,received multiple grey white to grey brown linear cores measures 0.3 to 1.0cm. entire tissue processed.,section show cores of fibroadipose tissue with an invasive neoplasm composed of cells in sheets and glands. the cells show increased n:c ratio pleomorphic nucleus with eosinophilic to clear cytoplasm. there is moderate intra tumoral lymphocytic infiltrate.,biopsy from left breast lump:invasive ductal carcinoma nos grade 3.modified bloom richardson score is 8 9.tubular formation 3nuclear pleomorphism 2mitotic activity 3 8 9
MR1715606,left breast lump malignant.,left breast lump core biopsy.,received multiple grey white to grey brown linear cores measures 0.5 to 1.2cm. entire tissue processed.,section show linear cores of tissue harboring a neoplastic lesion arranged in sheets and islands. the cells have pleomorphic round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma show desmoplasia. mitotic figures are discerned. bizzare giant forms noted.,left breast lump core biopsy :invasive carcinoma grade iii.modified br score is 8 9.tubular formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1715616,carcinoma left breast.,left modified radical mastectomy.,received in : formalin.procedure : modified radical mastectomylaterality : left breast.total dimensions : medial lateral : 17 cm superficial deep : 5 cm superior inferior : 16 cmskin ellipse : 12x6 cmnipple : normalscar surgical defect : not seentumor : singletumor size : 3x3x2 cmlocation of tumor : lower outer quadrantmargins of tumor : ill defineddeep margin : 1 cmmuscle : absent adjacent breast : fibrofattyaxillary tail : 5x4x3 cmsize of largest node: 08x0.7x0.7 cm. cut surface shows fatty infiltration.,multiple sections studied from the breast parenchyma show an infiltrative neoplasm arranged in cords sheets and nests of neoplastic cells exhibiting increased n c ratio pleomorphic vesicular nuclei with occasional prominent nucleoli. the surrounding stroma shows dense desmoplastic response. lymphovascular invasion is identified.perineural invasion is not seen. areas of lobular carcinoma in situ noted.,left breast left modified radical mastectomy :invasion carcinoma with lobular features grade 2. modified bloom richardson score is 6( 3+2+1). tumor measures 3 cm in greatest dimension and is located in the lower outer quadrant. lobular carcinoma in situ : seen. lymphovascular invasion is identified. perineural invasion is not seen. posterior resection margin is uninvolved by tumor. nipple and areola are uninvolved by tumor.lymph nodes: four out of ten lymph nodes shows metastatic tumor deposit(4 10). size of the largest tumor deposit measures 0.7 cm in greatest dimension. no extranodal extension is seen.
MR1715617,right breast lump inflammatory carcinoma.,biopsy from right breast lump.,received multiple grey white linear cores measures 0.5 to 1.0cm. entire tissue processed.,section shows cores of breast tissue with an invasive neoplasm composed of cells in sheets nests and singly scattered forms. the cells show moderate nuclear pleomorphism clear to eosinophilic cytoplasm. extensive areas of ductal carcinoma in situ comedo type and solid type noted.,biopsy from right breast lump:invasive ductal carcinoma nos with comedo ductal carcinoma in situ.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1715620,left breast lump malignant.,left breast lump core biopsy.,received multiple grey white to grey yellow linear cores measures 0.5 to 1.2cm. entire tissue processed.,section show linear cores of tissue with an infiltrating neoplastic lesion arranged in infiltrating cords and islands and sheets. the cells have round to oval slightly eccentically placed hyperchromatic nuclei and moderate amount of pale eosinophilic to clear cytoplasm. stroma show desmoplasia. mitotic figures discerned.,left breast lump core biopsy :invasive ductal carcinoma.nuclear grade ii.
MR1715626,right breast lump malignant.,right breast mass.,received multiple grey linear cores measures 1 to 1.5 cm. entire tissue processed.,section from the breast parenchyma shows a infiltrative lesion arranged in sheets and nests. the cells are round to oval nuclei with hyperchromatic nuclei few with prominent nucleoli scant cytoplasm. mitosis 4 5 10hpf. stroma shows lymphoplasmcytic infiltrates.,right breast lump core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 7(3+2+2).
MR1715645,left breast lump malignant.,left breast lump.,received multiple grey white to grey brown linear cores measures 0.5 to 0.8cm. entire tissue processed.,section shows breast parenchyma with infiltrative neoplasm arranged in sheets and nests. the cells are round to oval hyperchromatic nuclei with abundant eosinophilic cytoplasm. stroma shows lymphocytes infiltrative. mitosis 5 6 10hpf.,left breast lump core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 7(3+2+2).
MR1715675,left breast lump carcinoma breast.,biopsy from left breast.,received 7 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section show tissue cores harboring an infiltrative lesion arranged in cords tubules and nests of neoplastic cells exhibiting increased nucleo cytoplasm ratio nuclear hyperchromasia pleomorphism plasmacytoid appearance variable amount of eosinophilic cytoplasm. stroma shows desmoplasia.,biopsy from left breastinvasive carcinoma breast nos grade iimodified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1715676,multifocal liver space occupying lesion.,core needle biopsy of liver lesion.,received multiple grey white linear core measures 0.8 to 1.0cm. entire tissue processed.,section shows linear tissue cores of liver parenchyma harboring an infiltrative lesion arranged in sheets and cords. the individual tumor cells show increased nucleo cytoplasm ratio pleomorphic hyperchromatic nuclei and focally prominent nucleoli with variable amount of pale to clear cytoplasm. there is increase number of mitotic figures (3 4 hpf). the adjacent liver parenchyma is showing diffuse parenchymal disease.,core needle biopsy of liver lesion:malignant lesion of poorly differentiated origin.the possibilities considered are 1) metastatic carcinoma of glandular origin.please look for lesion in breast git and lung.2) poorly differentiated hepatocellular carcinoma.suggest ihc.
MR1715682,carcinoma left breast t4b.,left breast lump incision biopsy.,received multiple grey white to grey brown soft tissue bits altogether measures 0.8 x 0.7 x 0.3 cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump incision biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1715683,left breast lump carcinoma breast.,left breast lump biopsy.,received 3 grey white linear cores measures 0.6 to 0.7cm. entire tissue processed.,section shows linear tissue cores harboring an infiltrative lesion arranged in nests cords and individually dispersed cells. the individual tumor cells show increased nucleo cytoplasm ratio hyperchromatic pleomorphic nuclei and variable amount of pale eosinophilic cytoplasm. the stroma is dense fibrocollagenous.,left breast lump biopsy invasive ductal carcinoma grade 2.modified bloom richardson score score 7 9.tubule formation 3nuclear pleomorphism 2mitotic activity 2 7 9
MR1715695,mass right breast carcinoma.,right breast biopsy.,received multiple grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows multiple cores of breast tissue with an invasive neoplasm showing glandular and nested pattern. the cells show moderate to abundant clear to vacuolated cytoplasm hyperchromatic nucleoli with moderate nuclear pleomorphism. mitosis is increased.,right breast biopsy:invasive ductal carcinoma (nos). grade 2modified bloom richardson score is 6 9.tubular formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR1715729,right breast lump carcinoma.,biopsy from right breast.,received multiple grey white linear cores measuring 0.8 to 1cm. entire tissue processed.,section shows multiple cores of breast tissue with an invasive neoplasm with cells in nests and glands.the cells show moderate to abundant eosinophilic cytoplasm moderate nuclear pleomorphism and hyperchromatism with prominent nucleoli. adjacent ductal carcinoma in situ cribriform and comedo type present. perineural invasion present.,biopsy from right breast:invasive ductal carcinoma nos grade 2 with ductal carcinoma in situ and perineural invasion.modified bloom richardson score is 6 9.tubular formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR1715732,left breast mass carcinoma.,left breast.,received multiple grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows infiltrative neoplasm arranged in sheets and nests. the neoplasm cells shows round to oval hyperchromatic nuclei abundant cytoplasm. adjacent stroma shows lymphoplasmacytic infiltration. mitotic figures are 5 5 10hpf.,left breast core biopsy :invasive ductal carcinoma grade 2. modified br score is 7(3+2+2).
MR1715785,carcinoma left breast.,left breast left modified radical mastectomy.,received in : formalinprocedure : mastectomy laterality : left total dimensions : medial to lateral : 20 cm superficial to deep : 3.8 cm superior to inferior : 16 cmskin ellipse : 14x8.5 cm nipple : normal scar surgical defect : not seentumor : singletumor size : 2.5x2x2 cm location of tumor : central region margins of tumor : ill defined deep margin : 1.5 cmmuscle : absent adjacent breast : free of tumor axillary tail : 6.5x4x1.5 cmsize of largest node : 1x0.4x0.3cm,section from the breast parenchyma shows an infiltrating neoplasm arranged in tubules nests and sheets. the cells are round to oval with vesicular nucleai with abundant eosinophlic cytoplasm. few with prominent nucleoli lymphoplasmacytic infiltration is seen. brisk mitotic activity seen. area of dcis component seen with solid and cribriform pattern are seen.,left breast left modified radical mastectomy: invasive ductal carcinoma grade ii. modified br score is 6 9.tubule formation : 2nuclear pleomorphism: 2mitotic figures : 2 6 9 tumor measures 2.5 cm in greatest dimension and is located in the central quadrant. ductal carcinoma in situ identified solid and cribriform pattern seen measures 0.5 cmlymphovascular invasion not identified.perinural invasion not identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: 12 lymph nodes metastasis: 0 (0 12). summary:left breast left modified radical mastectomy: invasive ductal carcinoma grade ii.
MR1715823,carcinoma breast post rt.right lung mass carcinoma lung. metastasis.,right lung mass biopsy.,received multiple grey white to grey brown linear cores measures 0.4 to 0.6cm. entire tissue processed.,section shows multiple linear cores with a tumor arranged in nests and sheets. the tumor cells show moderate to marked pleomorphism with increased nuclear cytoplasmic ratio occasional small nucleoli and dense eosinophilic to foamy cytoplasm. focal keratinisation with keratin pears are noted. few mitotic figures are discerned. focal necrosis is seen.,right lung mass biopsy:poorly differentiated carcinoma favor squamous carcinoma.
MR1715833,carcinoma left breast,a) lumpectomy:b) axillary lumpectomy:,a)received lumpectomy specimen measuring 6x5x3.5cm.skin ellipse measures 5.5x.cm.skin show healed scar measures 2cm.serial section shows grey white fibrotic areas measuring 1x1x0.5cm.distance from margins:superior margin : 1.3cminferior margin :2.3cmlateral margin :1.4cmmedial margin : 3cmdeep margin : 2.5cmb) received fibrofatty tissue measures 8.5x6.5x4cmlargest lymph node measures 1.8x1x0.5cm. cut surface grey white.,lumpectomy : multiple section studied shows fibrosis necrosis lymphoplasmacytic infiltration and foreign body giant cells post lumpectomy changes . there is no evidence of residual viable tumor present.resected margin:superior margin : free of tumorinferior margin : free of tumormedial margin : free of tumorlateral margin : free of tumordeep margin : free of tumorall resected margins are free of tumor.b) axillary lumpectomy : 14 lymph nodes no deposits of tumor.,lumpectomy wide excision:no residual viable tumor presentfibrosis necrosis and lymphoplasmacytic infiltration and foreign body giant cells.all resected margins are free of tumor.lymph nodes: 14 lymph nodes no deposits of tumor.pathological grade : ypt0n0.
MR1715856,left breast mass carcinoma breast.,biopsy from left breast.,received 6 greywhite cores measuring 0.8 to 0.9cm. entire tissue processed.,section shows cores of fibrocollagenous tissue with an invasive neoplasm in nests and cords. the cells show moderate nuclear pleomorphism and hyperchromatism and eosinophilic vacuolated cytoplasm. areas of necrosis noted.,biopsy left breast:invasive ductal carcinoma (nos) grade iimbr score (3+2+2) is 7 9.
MR1715867,right breast mass carcinoma breast papillary carcinoma.,biopsy from right breast mass.,received 7 greywhite linear cores measuring 0.4 to 0.6cm. entire tissue processed.,section shows cores of breast tissue with neoplasm in glands and papillae showing clear to eosinophilic cytoplasm moderate nuclear pleomorphism. occasional mitotic figures noted and focal collection of foam cells seen in papillary stroma.,biopsy from right breast mass:invasive carcinoma with papillary features.mbr score (2+2+2) is 6 9 grade ii
MR1715899,right breast lump p o carcinoma breast.,right breast lump.,received multiple linear cores measures 0.8 to 1cm. entire tissue processed.,section shows a infiltrative lesion arranged in sheets and nests. the cells are round to oval hyperchromatic nuclei with abundant eosinophilic cytoplasm adjacent stroma show lymphoplasmacytic infiltration. mitosis 5 6 10hpf.,right breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1715925,right breast lesion malignant.,biopsy from right breast.,received multiple grey white linear cores measures 0.8 to 1.0cm. entire tissue processed.,section shows cores of breast tissue with an infiltrating neoplasm composed of cells in glands acini and nests. the cells show clear to eosinophilic cytoplasm moderate nuclear pleomorphism and increased mitotic figures. stroma is desmoplastic with scattered infiltration.,biopsy from right breast:invasive carcinoma of ductal origin nst grade 2.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphic 2mitotic figures 2 7 9
MR1715933,right breast lump.,biopsy from right breast.,received multiple grey white linear cores measures 0.8 to 1.0cm. entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged in clusters and cords. the neoplastic cells have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is elastotic.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1715949,right breast lump carcinoma breast.,right breast lump biopsy.,received multiple linear cores measures 0.6 to 0.8cm. entire tissue processed.,section shows cores of breast tissue with preserved lobular architecture with glands showing preserved epithelial and myoepithelial cells.few cells show clear cells change. few glands show ductal hyperplasia.,right breast lump biopsy:benign breast disease.no evidence of malignancy in the material provided.
MR1715984,right breast lump malignant,biopsy from right breast lump.,received 5 grey white linear cores measures 0.3 to 0.6cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in islands trabecular and diffuse sheets comprising of atypical cells with pleomorphic round to oval hyperchromatic nuclei prominent nucleoli and moderate amount of eosinophilic cytoplasm. mitotic figure discerned 2 3 hpf . interspersed lympocytes and plasma cells are noted. adjacent areas show desmoplastic change. no areas of necrosis identified.,biopsy from right breast lump:invasive ductal carcinoma grade 3modified bloom richardson score is 3+2+2 8 9.
MR1715994,carcinoma left breast nact,a) left breast.b) left axillary lymph node.,a) received wide local excision left breast measures 8x7x3.2cm on serial section firm grey white lesion measures 1.5x1.3x1.2cm. distance from margins:superior margins :0.6cmninferior margin : 2cmmedial margin : 3cmlateral margin : 2.5cmdeep margin : 0.5cmb) received single fibrofatty tissue measures 5x4x2cmlargest lymph node measures 0.8x0.5x0.4cm.,a) residual viable tumor presentinvasive ductal carcinoma focal areas of ductal carcinoma in situ present measure 0.3cm low grade modified bloom richardson score is 6 9 nuclear grade tubule formation 2nuclear pleomorphism 2mitotic activity 2lymphovascular invasion is not present.perineural invasion si not presentresectedl margin superior is free of tumor.inferior margin shows epithelial hyperplasia and atypical hyperplasia. there is no ductal carcinoma in situinked margin is free of tumor.medial margins is free of tumorlateral margin is free of tumordeep margin is free of tumor.b) 8 nodes no deposit of tumor.0 8,a) viable tumor present invasive ductal carcinomanuclear grade iilymphovascular invasion not present.resected margin superior medial lateral and deep margin : free of tumor.inferior margin shows atypical hyperplasia.inked margin is free of tumor.b)axillary lymph node:8 lymph nodes no deposit of tumor.0 8
MR1716037,right breast lump.,right breast lump core biopsy.,received four linear cores measures 0.8 to 1.0cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1716055,right left breast lump p o carcinoma breast.,biopsy from left breast.,received multiple grey white linear cores measures 0.4 to 0.6cm. entire tissue processed.,section shows cores of breast tissue with an invasive neoplasm composed cells in nests and glands with moderate eosinophilic cytoplasm pleomorphic nucleoli with moderate nuclear pleomorphism. stroma is desmoplastic and hyalinized.,biopsy from left breast:invasive ductal carcinoma (nos) grade imodified bloom richardson score is 5 9.tubule formation 2nuclear pleomorphism 2mitotic activity 1 5 9
MR1716069,left breast lump p o carcinoma breast.,biopsy from left breast lump.,received multiple linear cores measures 0.6x0.8cm. entire tissue processed.,section from the breast parenchyma show a infiltrative lesion arranged in nests and vague glandular pattern. the cells foamy the lesion are round to oval vascular nuclei abundant eosinophilic cytoplasm with areas of necrosis. mitosis 2 3 10hpf adjacent stroma show lymphocytes. areas of ducal carcinoma in situ with comedo pattern.,biopsy from left breast lump :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1) ductal carcinoma in situ of comedo pattern with intermediate nuclear grade is seen.
MR1716084,right breast lump p o carcinoma breast.,right breast lump.,received multiple grey white linear cores measures 0.6x0.9cm. entire tissue processed.,section from the breast parenchyma shows a infiltrating neoplasm arranged in tubules and nests. the cells forming the lesion are round to oval hyperchromatic nuclei with abundant cytoplasm adjacent stroma shows lymphoplasmacytic infiltration. mitosis 3 3 10hpf.,right breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1716086,right breast lump p o carcinoma breast.,right breast lump.,received multiple grey white linear cores measures 0.5 x 0.6 cm. entire tissue processed.,section from the breast parenchyma shows the infiltrative neoplasm arranged in sheets and nest. the cells forming the neoplasm are round to oval hyperchromatic nuclei with abundant eosinophilic cytoplasm. mitosis 6 7 10hpf.,right breast lump core biopsy :invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+2+3)
MR1716089,large exophytic left breast mass carcinoma.,biopsy from left breast mass.,received 4 grey white to grey brown soft tissue bits altogether measures 0.8 to 1cm. entire tissue processed.,section shows linear tissue cores harboring an infiltrative lesion arranged in sheets and nests. the individual tumor cells show increased nucleo cytoplasmic ratio hyperchromatic nuclei with inconspicuous nucleoli and indistinct cytoplasmic border .the intervening stroma shows dense lymphoplasmacytic infiltrate with numerous foamy histiocytes. focal necrosis is present.,biopsy from left breast mass:invasive ductal carcinoma grade iiimodified bloom richardson score is 8 9tubule formation 3nuclear pleomorphism 2mitotic figures 3 8 9 focal necrosis is present.
MR1716096,right breast lump possibility of carcinoma breast.,biopsy from right breast lump,received 6 linear cores measures 0.6 to 0.8cm. entire tissue processed,section shows linear tissue harboring an infiltrative lesion arranged in glandular pattern nests and cords.the individual tumor cells show increased nucleo cytoplasmic ratio hyperchromatic pleomorphic nuclei with variable amount of pale eosinophilic cytoplasm. the intervening stroma shows dense fibrocollagenous eosinophilic connective tissue and mature adipose tissue extensive hemorrhage is seen.,biopsy from right breast lump:iinvasive ductal carcinoma grade imodified bloom richardson score is 5 9tubule formation 2nuclear pleomorphism 2mitotic figures 1 5 9
MR1716103,left breast lump p o carcinoma breast.,biopsy from left breast.,received multiple grey white to grey brown linear cores measures 0.3 to 1.0cm. entire tissue processed.,section shows multiple linear cores showing infiltrative neoplasm arranged in cords sheets nests and focus of ducal carcinoma in situ neoplastic cells are round to oval hyperchromatic nuclei with abundant cytoplasm adjacent stroma shows focal collection of lymphocytes mitotic figures discerned.,biopsy from left breast:infiltrative ductal carcinoma grade 2.modified bloom richardson score is 7 9.ductal carcinoma in situ (solid type).tubular formation 3nuclear pleomorphism 2mitotic activity 2 7 9
MR1716119,left breast lump.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.8 to 0.9cm. entire tissue processed.,smear cores of breast parenchyma harboring a neoplasm arranged in nest lobules and cords. the neoplastic cells have hyperchromatic nuclei and moderate amount of cytoplasm. the involving stroma is elastotic.,biopsy from left breast lump:invasive carcinomasuggest ihcnote:case discussed with dr.senthil rajappa
MR1716126,right breast lump carcinoma breast.,right breast biopsy.,received multiple linear cores measures 0.8 to 1cm. entire tissue processed.,section shows linear tissue cores harboring an infiltrative lesion arranged in sheets nests and cords. the individual tumor cells show increased nucleo cytoplasmic ratio pleomorphic hyperchromatic nuclei with only focally prominent nucleoli. the surrounding stroma is dense fibrocollagenous. there is lymphoplasmacytic infiltrate in the stroma.,right breast biopsy:invasive ductal carcinoma grade 2modified bloom richardson score 7 9.tubule formation 3nuclear pleomorphism 2mitotic activity 2 7 9
MR1716163,right breast lump malignant.,biopsy from right breast.,received multiple grey white linear cores measures 0.8 to 0.9cm. entire tissue processed.,section shows cores of fibro adipose tissue with an invasive neoplasm composed of cells in sheets and nests with moderate eosinophilic cytoplasm pleomorphic hyperchromatic nuclei and increased mitotic figures.,biopsy from right breast:invasive ductal carcinoma nos grade 2.modified bloom richardson score is 7 9.tubular formation 2nuclear pleomorphic 2mitotic activity 3 7 9
MR1716164,known case of carcinoma breast.left breast lump p o carcinoma breast.,biopsy from left breast lump.,received multiple grey white to grey brown linear cores measures 0.6 to 0.7cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in nests tubules and cords. the cells round to oval pleomorphic nuclei with few showing prominent nucleoli and abundant cytoplasm. mitotic figures are seen. areas of hemorrhage seen.,biopsy from left breast lump:invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9.tubulae formation 2nuclear pleomorphism 3mitotic activity 1 6 9
MR1716182,right breast lump p o carcinoma breast.,right breast lump core biopsy.,received multiple linear cores measures 0.8 to 1cm. entire tissue processed.,section shows linear cores of tissue with an infiltrating neoplastic lesion arranged in cords and sheets. the cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm. mitotic figures discerned. stroma is desmoplastic.,right breast lump core biopsy:invasive ductal carcinoma grade 2.modified bloom richardson score 6 9.tubular formation 3nuclear pleomorphism 2mitotic activity 1 6 9
MR1716186,left breast lump p o carcinoma breast.,left breast core biopsy.,received multiple grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic pleomorphic nuclei variable prominent nucleoli and moderate to abundant eosinophilic cytoplasm. stroma is showing lymphoplasmacytic infiltrate.,left breast core biopsy:invasive carcinoma with medullary features grade 3. modified bloom richardson score is 8(3+3+2).
MR1716199,left breast lump carcinoma breast.,biopsy from left breast.,received multiple linear cores measures 0.8 to 1cm. entire tissue processed.,section shows cores of fibro adipose tissue with an invasive neoplasm in cords and nests having moderate eosinophilic to clear cytoplasm pleomorphic hyperchromatic nuclei. stroma is desmoplastic and hyalinizied.,biopsy from left breast:invasive ductal carcinoma nos grade 2.modified bloom richardson score is 6 9.tubule formation 2nuclear pleomorphism 2mitotic activity 2 6 9
MR1716208,right breast lump p o carcinoma breast.,biopsy form right breast lump.,received multiple grey white linear cores measures 0.6 to 0.9cm. entire tissue processed.,section show linear cores of breast parenchyma harboring an infiltrating neoplasm arranged in cords. the lesional cells have pleomorphic round to irregular hyperchromatic nucleus and moderate cytoplasm. ducal carcinoma in situ component with comedo necrosis is present.,biopsy form right breast lump:invasive ductal carcinoma (nos) with ductal carcinoma in situ grade ii.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9 ductal carcinoma in situ with comedo necrosis seen.
MR1716234,left breast lump p o carcinoma breast.,trucut biopsy from left breast lump.,received multiple grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue processed.,section show linear tissue cores harboring a lesion arranged in sheets and nests. the individual tumor cells shows increased nucleo cytoplasmic ratio hyperchromatic nuclei with occasional prominent nucleoli and moderate amount of eosinophilic cytoplasm. focal cribriform pattern is noted. the intervening stroma is fibrocollagenous shows focal myxoid ahanges and infiltrated by lymphocytes. perineural invasion is seen.,trucut biopsy from left breast lump.invasive ductal carcinoma nos grade 1.modified bloom richardson score is 5 9.tubular formation 2nuclear pleomorphism 2mitotic activity 1 5 9.
MR1716248,right breast lump p o carcinoma breast.,biopsy from right breast..,received multiple grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue processed.,section shows cores of breast tissue harboring neoplasm composed of extensive ductal carcinoma in situ solid and comedo type with areas of invasion in nested and glandular pattern. the cells of invasive carcinoma show moderate eosinophilic cytoplasm pleomorphic hyperchromatic nuclei with prominent nucleoli. areas of microcalcification noted.,biopsy from right breast:ductal carcinoma in situ (comedo).extensive ductal carcinoma in situ (comedo pattern ) with foci of invasive ductal carcinoma nos grade 2.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic activity 2 7 9
MR1716283,right breast lump p o carcinoma breast.,biopsy from right breast.,received multiple linear cores measures 0.4 to 0.6cm. entire tissue processed.,section shows cores of fibrocollagenous tissue with an invasive neoplasm composed of cells in sheets and ribbon the cells shows moderate eosinophilic to vacuolated cytoplasm pleomorphic hyperchromatic nuclei and prominent nucleoli. these brisk mitosis peritumoral lymphocytic infiltrate noted. areas of necrosis present.,biopsy from right breast:invasive carcinoma ductal nos grade 3.modified bloom richardson scores 8 9.tubular formation 3nuclear pleomorphism 2mitotic activity 3 8 9
MR1716307,carcinoma right breast.,a) sentinel lymph node.b) wide local excision right breast.c) circumferential margin.,a) received fibrofatty tissue measures 3x3x0.5cm three lymph nodes isolated. largest lymph node measures 1.5x1.5x1cm. entire tissue processed.b) received right breast lumpectomy specimen measuring 6.5x6x4cm .skin ellipse measures 3x1cm.cut surface shows tumor measuring 2x1.5x1cm.distance from the margins :superior : 1.5cm.inferior : 0.5cm.medial : 0.5cm.lateral : 1.5cm.deep : 0.1cm.c) received fibrofatty tissue measuring 5.5x2x2cm.,a)sentinel lymph node :3 nodes no metastatic deposits of tumor.b) wide local excision (lumpectomy) right breast :tumor : tumor in composed of pleomorphic cells with hyperchromatic nucleus with eosinophilic cytoplasm. maximum dimension of tumor is 2cm.invasive ductal carcinoma is 1.5cm mbr score(6 9)tubular formation : 2nuclear pleomorphic : 2mitotic figures : 2 6 9 nuclear grade ii.ductal carcinoma in situ present measures 0.5cm with cribriform pattern and comedonecrosis.lymphovascular invasion is not present.perineural invasion is not present.resected margins superior margin is free of tumorinferior medial and lateral margins show adenosis and are free of tumor.deep margin is free of tumor.c) circumferential margins : all margins (12 0 clock 3 0 clock 6 0 clock 9 clock ) :are free of tumor.,sentinel lymph node : 3 nodes no deposits of tumor.wide local excision(lumpectomy) right breast :maximum dimension of tumor is 2cm.invasive ductal carcinoma 1.5cmductal carcinoma in situ 0.5cm.nuclear grade ii.lymphovascular invasion not present.perineural invasion not present.all resected margins and circumferential margins are free of tumor.
MR1716345,right breast lump p o carcinoma breast.,biopsy from right breast.,received multiple linear cores measures 0.6 to 0.8cm. entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged in cords and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is elastotic.,biopsy from right breast:invasive carcinoma grade 2.modified bloom richardson score is 6 9.tubule formation 3nuclear pleomorphism 2mitotic activity 1 6 9
MR1716359,carcinoma breast post treatment,liver lesion biopsy.,received multiple linear cores measures 0.5 to 1.5cm. entire tissue processed.,section show linear tissue cores harboring of liver parenchyma harboring a lesion arranged in sheets nests and occasional vague acini. the tumor cells exhibit polygonal with increased nucleo cytoplasmic ratio pleomorphic hyperchromatic nuclei with prominent nucleoli and abundant vacuolated cytoplasm. the adjacent liver parenchyma is non cirrhotic.,liver lesion biopsy :poorly differentiated carcinoma favor metastatic adenocarcinoma.suggest ihc.
MR1716363,known case of carcinoma left breast.,biopsy from chest wall lesion,received 5 grey white linear cores measures 1 1.5cm. entire tissue processed.,linear cores of fibrous tissue harboring an infiltrating lesion arranged in cords and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm.,biopsy from chest wall lesion:invasive carcinoma suggestive of recurrent carcinoma in a known case of carcinoma breast.
MR1716383,left breast lump malignant,biopsy from left breast.,received 4 grey white to grey yellow linear cores measures 1 to 1.2cm. entire tissue processed.,sections studied from linear breast cores harbor tumor tissue arranged in tubules sheets and clusters. the tumor cells are round to oval with moderate cytoplasm with pleomorphic hyperchromatic nuclei . the tumor cells are seen invading stroma.,biopsy from left breast:invasive duct cell carcinoma grade iimodified bloom richardson score is 6 9 .tubule formation : 2nuclear pleomorphism : 2mitotic figures :2 6 9
MR1716393,carcinoma right breast.,a) biopsy from right bcs:b) axillary clearance.,a)received wide local excision specimen measures 6x4x3cm .overlying skin flap measures 4x1.5cm .on cut surface grey white lesion is seen measures 1.5x1x1cm.distance from margin:superior margin : 1.5cmmedial margin : 2cminferior margin : 0.2cmlateral margin :0.2cmdeep margin :1.5cm.b) fibrofatty tissue measures 5x4x3cm largest lymph node 1.5x0.2x0.7cm. cut surface grey white.,section from breast parenchyma shows an infiltrating lesion arranged in cords and sheets. the tumor cells have pleomorphic round to irregular nucleus coarse chromatin few with prominent nucleoli and moderate cytoplasm. brisk mitoses are noted,a) biopsy from right bcs:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation 3nuclear pleomorphic 2mitotic figures 2tumor measures 1.5cm in greatest dimensionductal carcinoma in situ is not present.lymphovascular invasion is presentperineural invasion is not identified lateral margin shows lymphovascular emboli 0.2cm away from inked margin.all margins of resection including deep are free of tumor.b) axillary clearance:six lymph nodes out of thirteen lymph nodes show metastatic deposit largest tumor deposit measures 1.5cm in greatest dimension.perinodal spread present.
MR1716394,carcinoma left breast.,a) left breast conservative surgery.b) left sentinel lymph node biopsy(blue + hot node).c) left sentinel lymph node biopsy(nonblue + nonhot node).d) revised lateral margin,a) received fibrofatty tissue measures 7x5.5x4cm. skin ellipse is measures 3x0.5cm.on serial sectioning a grey white illdefined lesion measures 2x1.5x1.0cm is seen at respective distances :distance from margins :superior : 2.3cm.inferior : 2cm.medial : 2.4cm.lateral : 2.5cm.deep : 1cm.b) received two fibrofatty tissue measures 2x1x0.8cm. both are inked blue.larger fibrofatty tissue measures 2x1x0.5cm smaller fibrofatty tissue measures 0.5x0.5x0.5cm. isolated 3 lymph nodes. largest measures 0.9x0.5x0.4cm. cut surface fatty infiltration inked blue.c) received single fibrofatty tissue measures 1.5x1x0.8cm. isolated one lymph node measures 0.8x0.8x0.5cm. entire tissue processed.d) received fibrofatty tissue measures 4x2.5x1cm one surface shows attached thread (stitch away from tumor.),a) left breast conservative surgery :tumor :the section shows clumps groups of pleomorphic cells with hyperchromatic nucleus. invasive ductal carcinoma.maximum dimension of tumor is 2cm.invasive ductal carcinoma component measures 1.2cm.tubular formation : 2nuclear pleomorphic : 2mitotic figures : 2 6 9 nuclear grade ii.ductal carcinoma in situ present and measures 0.8 cm(cribriform pattern and comedonecrosis present)lymphovascular invasion not present.perineural invasion not present.all resected margins are free of tumor.b) left sentinel lymph node(blue+hot node) 3 nodes show no metastatic deposits of tumor.(0 3)c) non blue non hot node : one node shows no metastatic deposit of tumor.(0 1)d) revised margin : shows fibrofatty tissue : free of tumor.,a) left breast conservative surgery :maximum dimension of tumor is 2cm.invasive ductal carcinoma measures 1.2cm.nuclear grade ii.ductal carcinoma in situ in measures 0.8cm with cribriform pattern and comedonecrosis.lymphovascular invasion not present.perineural invasion not present.b) left sentinel lymph node(blue+hot node) : 3 nodes no metastatic deposits of tumor(0 3).c) non blue non hot node : one node no metastatic deposits of tumor (0 1).d) revised margin : fibrofatty tissue free of tumor
MR1716416,right carcinoma breast.,a) right breast wide excision specimen.b) right axillary sentinel nodes.c) right level i ll axillary nodes.d) right level 3 lymph nodes.,a) received wide excision right breast lump measures 5x4.5x3cm. skin ellipse 3.5cm. x 1cm. on serial section grey white firm area seen measures 1.5x1x1cm.which is located at following distance from respective margins:superior margin 1cm.interior margin 1.5cm.medial margin 1.5cm.lateral margin 2cm.deep margin 1.5cm.b) received single fibrofatty tissue measures 2x1x0.8cm.isolated 2 lymph nodes. largest lymph node measures 1.2x1x0.8cm. cut surface shows fatty infiltrate.c) received fibrofatty tissue measures 6x4.5x2 cm. largest lymph node measures 7 3 1x1x0.5.d) received fibrofatty tissue measures 2x1x1 cm. entire tissue processed.,a) right breast conservation,invasive ductal carcinoma grade 2.modified bloom richardson sccore: 6 9.tubule formation : 2.nuclear pleomorphism : 02.mitotic activity : 02.tumor measures 1.5cm. in greatest dimension.dcis is not present.lymphovascular and perineural invasion are not present.all resected margins including deep margin are free of tumor.b) right axillary sentinel nodes:two lymph nodes identified negative for malignancy (0 2).c) right level i ll axillary nodes:eleven lymph nodes isolated all negative for malignancy (0 11)d) right level 3 lymph nodes:four lymph nodes isolated negative for malignancy (0 4).
MR1716433,lump in outer quadrant of right breast carcinoma breast.,right breast lesion biopsy upper outer quadrant (uoq).,received three linear cores that measure 0.3 to 1.1cm . entire tissue is processed.,sections show linear tissue cores harboring an infiltrative lesion arranged as tubules cords and small nests of cells exhibiting increased nucleocytoplasmic ratio hyperchromatic pleomorphic nuclei with inconspicuous nucleoli. the intervening stroma shows dense fibrocollagenous infiltrated by lymphocytes and plasma cells. occasional tubules show presence of acellular eosinophilic material.,right breast lesion biopsy(uoq) :invasive carcinoma nst.modified br score is 6 9 grade ii.tubular formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1716436,case of right breast carcinoma.,a)right breast wide excision.b) right axillary dissection.,a) received lumpectomy specimen measures 7.5x4x4cm. skin ellipse measures 4.3x0.8cm on serial sections show grey white firm ill defined lesion measures 2x1.5x1.4cm.distance from margins:superior margin: 1.8cminferior margin :1cmmedial margin : 2.5cmlateral margin :1.7cmdeep margin : 2cmb) single fibrofatty tissue measures 11x7x2cmlargest node measures 1.8x1.5x0.8cm. cut surface grey brown.dissected 19 nodes,a)residual viable tumor present measuring 2x1.5x1.4cmmost the tumor shows ductal carcinoma in situ solid and cribriform measures 1.5cm.focus of invasive carcinoma measures 0.5 cm.surrounding areas shows dense fibrosis lymphoplasmacytic infiltration and ducts show epithelial hyperplasia and adenosis. lymphovascular invasion not identifiedperineural invasion not identified.b) right axillary dissection: 16 nodes no deposit of tumor.,a)right breast post nact wide excision: residual viable tumor present measures 2x1.5x1.4cm invasive ductal carcinoma measures 0.5cmductal carcinoma in situ (low grade) measures 1.5cm.lymphovascular invasion not identifiedperineural invasion not identified.all resected margins free of tumor.b) right axillary dissection:16 lymph nodes. no deposit of tumor.pathological stage: ypt1no
MR1716445,right breast lump p o carcinoma breast.,biopsy from right breast.,received 4 linear cores measures 0.3 to 1.2cm. entire tissue processed.,section shows cores of breast tissue with an invasive neoplasm predominantly in cords and nests. the cells show moderate nuclear atypia with eosinophilic to clear cytoplasm. focal peritumoral inflammatory infiltrate noted. stroma is desmoplastic and hyalinized.,biopsy from right breast:invasive ductal carcinoma (nos).mbr score (3+2+2) is 7 9 grade ii.
MR1716467,left breast mass carcinoma breast.,left breast carcinoma biopsy.,received multiple linear cores measures 0.2 to 1.4cm. entire tissue processed.,section shows breast parenchyma with an infiltrating lesion arranged in sheets nests and cords. cells have moderately pleomorphic hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. high mitotic activity noted. stromal desmoplasia and lymphocytic infiltration is seen.,left breast carcinoma biopsy:invasive carcinoma no special type grade 2.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic activity 2 7 9
MR1716472,left breast lump p o carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.5 to 0.8cm. entire tissue processed.,section from left breast lump shows sheets clusters and singly scattered cells. the cells show round nucleus conspicuous nucleoli and scanty cytoplasm. few lymphoid aggregates seen.,biopsy from left breast lump:invasive carcinoma nos grade 2.modified bloom richardson score is 6 9.tubular formation 3nuclear pleomorphism 2mitotic activity 1 6 9
MR1716481,right breast mass (7 o clock) carcinoma breast.,biopsy from right breast mass.,received multiple linear cores measures 0.5 to 1.3cm. entire tissue processed.,section from right breast shows clusters of mildly pleomorphic cells showing vesicular nucleus conspicuous nucleoli and eosinophilic cytoplasm.,biopsy from right breast mass:invasive carcinoma nos grade 2modified bloom richardson score is 6 9.tubular formation 2nuclear pleomorphism 3mitotic activity 1 6 9
MR1716507,known case of carcinoma left breast ( post op).,biopsy from left axillary lesion.,received 5 grey white to grey brown linear cores measures 0.3 to 0.4cm. entire tissue processed.,section show multiple linear cores harboring a infiltrative neoplasm arranged in sheets glands and nests. the cells forming the lesion are round to oval hyperchromatic nuclei with scant to moderate cytoplasm inflammatory infiltrates composed of neutrophils macrophages and focal collection of lymphocytes.,biopsy from left axillary lesion:metastasis carcinoma in a known case of carcinoma breast.(the neoplastic cells show more of apocrine myoepithelial features).kindly refer to the primary diagnosis for histopathologic categoization.
MR1716508,mass in right breast carcinoma breast.,right breast core biopsy.,received multiple linear cores measures 0.5 to 0.8 cm. entire tissue processed.,section shows tumor cells in tubules nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy:invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1716548,left breast lump p o carcinoma breast.,biopsy from left breast lump.,received multiple grey white to grey brown linear cores measures 0.6 to 0.8cm. entire tissue processed.,section shows linear tissue cores harboring an infiltrative lesion arranged in sheets nests and rare vague tubules composed of neoplastic cells showing increased nucleo cytoplasmic ratio pleomorphic hyperchromatic nuclei with occasional prominent nucleoli and scanty eosinophilic cytoplasm. the intervening stroma is dense fibrocollagenous and shows hemorrhage and hemosiderin pigment deposition.,biopsy from left breast lump:invasive carcinoma nos grade 2.modified bloom richardson score is 6 9.tubular formation 3nuclear pleomorphism 2mitotic activity 1 6 9
MR1716582,left breast lesion birad s 4c,biopsy from left breast lesion.,received multiple grey white to grey yellow linear cores measures 0.3 0.6cm. entire tissue processed.,section shows cores of breast parenchyma harboring a lesion confined to ducts predominantly solid pattern cribriform and micropapillary pattern. central comedo necrosis noted. cells have round to oval hyperchromatic nuclei and moderate cytoplasm. few bizarre forms noted. brisk mitotic activity noted. adjacent breast shows hyperplastic ducts and lymphoplasmacytic infiltrate.,biopsy from left breast lesion:suggestive of ductal carcinoma in situ (dcis) high grade (solid and comedo types) in view of extensive desmoplasia of stroma the the possibility of adjacent focus of invasion cannot be ruled out..
MR1716603,right breast lump birads iv and carcinoma breast.,right breast core biopsy.,received multiple grey white grey yellow linear cores measures 1 to 1.3. entire tissue processed,section shows cores of tissue infiltrated by tumor cells in cords and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. few signet ring cells are seen.,right breast core biopsy:invasive carcinoma with lobular feature grade 2 modified bloom richardson score is 7(3+3+1).
MR1716677,right breast lump birads 4.,right breast core biopsy.,received 4 grey white to grey brown linear cores measures 0.5 0.6cm. entire tissue processed.,section shows tumor cells in sheets and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1716678,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received 4 grey white to grey yellow linear cores measures 0.5 to 0.7cm. entire tissue processed.,section studied show breast tissue with abundant areas of fibromyxoid and fibrous areas harboring few foci of atypical cells. the cells are round to oval to with moderate cytoplasm with pleomorphic hyperchromatic nuclei. one of the ducts is fragmented and shows foci of necrosis.,biopsy from right breast:focus suspicious of ductal carcinoma in situ noted.needs clinical and imagiological correlation and repeat biopsy to exclude invasive focus.
MR1716702,left breast lump possibility of carcinoma breast.,left breast lump core biopsy.,received 4 grey white to grey brown linear cores measures 0.5 to 0.8cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score 6(3+2+1).
MR1716709,right breast lump p o carcinoma breast.,right breast lump core biopsy.,received 3 grey white to grey yellow linear cores measures 1.2 to 1.8cm. entire tissue processed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1716718,left breast lump possibility of carcinoma breast.,biopsy from left breast,received 3grey white to grey brown linear cores measures 0.4 0.6cm. entire tissue processed.,section shows 3 linear cores of breast parenchyma harboring an infiltrating lesion arranged in tubules and cords with large areas of fibrous . the lesional cells have mildly pleomorphic round hyperchromatic nucleus with moderate cytoplasm. areas of calcification seen.,biopsy from left breast:invasive duct carcinoma (nos) grade ii.modified bloom richardson score is 2+2+2 6 9.
MR1716724,left breast lump p o carcinoma breast.,left breast lump.,received multiple grey white to grey yellow linear cores measures 0.3 to 0.5cm. entire tissue processed.,section from the breast shows a infiltration neoplasm arranged in sheets and nest. the cells forming the lesion are round to oval hyperchromatic nuclei with scant to moderate cytoplasm. mitosis 3 4 10hpf.,left breast lump:infiltrating ductal carcinoma grade 2.modified bloom richardson score is 6 9.tubule formation 3nuclear pleomorphism 2mitotic activity 1 6 9
MR1716731,left breast lump p o carcinoma breast.,biopsy from left breast lump.,received multiple grey yellow to grey brown linear cores measures 1.2 to 1.4cm. entire tissue processed.,section shows infiltrate lesion arranged in sheets and nests. the cells are round to oval hyperchromatic nuclei with scant to moderate cytoplasm abundant stroma inflammatory infiltrate composed of lymphocytes. mitosis 3 4 10hpf.,biopsy from left breast lump:infiltrating ductal carcinoma grade 2.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic activity 2 7 9
MR1716740,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received 4 grey white linear cores measures 0.6 to 1cm. entire tissue processed.,sections showslinear breast cores harboring tumor arranged in diffuse sheets . the tumor cells are round to oval with scant cytoplasm hyperchromatic pleomorphic nucleus. the tumor cells are seen invading stroma. along with this lymphocytic infiltrate is seen admixed in fibromyxoid stroma.,biopsy from left breast:invasive duct cell carcinoma modified bloom richardson score is 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures :1 6 9
MR1716778,left breast lump possibility of carcinoma breast.,left breast lump core biopsy.,received 5 grey white to grey brown linear cores measures 0.6 to 1cm. entire tissue processed.,section shows tumor cells in nests cords and tubules. individual tumor cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1716811,metastatic carcinoma breast.,right and left ovaries and fallopian tubes bilateral salpingo oophorectomy.,received 2 ovaries with attached fatty tissue in the same container large measures 3x2.5x2 cm cut surface show folicular cyst measures 0.5 cm diameter.fatty tissue measures 2.5 cm cut surface shows cystic measures 1.5x1x0.5 cm.smaller measures 2.5x2.5x2 cm cut shows cyst measures 1x1x1 cm fatty tissue measures 2.5x2.5x2 cm,section from both ovaries shows normal ovarian paranchyma showing follicular cyst corpus albicans and congested blood vessel. both fallopian tubes and fimbrial ends are unremarkable. negative for malignancy.,right and left ovaries and fallopian tubes bilateral salpingo oophorectomy :shows benign ovarian tissue. negative for malignancy.
MR1716829,left breast mass carcinoma breast.,left breast mas core biopsy.,received 4 grey white to grey brown linear cores measures 1 1.2cm. entire tissue processed.,section shows tumor cells in nests and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mas core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1)
MR1716839,mass in right breast carcinoma breast.,right breast mass biopsy.,received multiple grey white to grey brown linear cores measures 1.2 to 1.4cm. entire tissue processed.,section shows cores of breast parenchyma harboring infiltrating lesion arranged in cords and tubules. the lesional cells are round to oval having moderately pleomorphic hyperchromatic nuclei and moderate cytoplasm. stroma is elastic. mitosis 6 7 10hpf.,right breast mass biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1716841,left breast lump p o carcinoma breast.,left breast lump core biopsy.,received multiple grey white to grey brown linear cores measures 1.2 to 1.4cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual tumor cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1716846,right breast lump p o carcinoma breast.,right breast lump.,received multiple grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section shows infiltrative neoplasm arranged in sheets and nests. the cells are round to oval hyperchromatic nuclei with eosinophilic cytoplasm .adjacent stroma shows lymphoplasmacytic infiltrate. mitosis 7 8 10hpf.,right breast lump:invasive ductal carcinoma grade 3.modified bloom richardson score is 8 9.tubular formation 3nuclear pleomorphism 2mitotic activity 3 8 9
MR1716863,carcinoma left breast.,fnac from left axillary node.,received multiple grey white to grey yellow linear cores measures 1.0 to 1.2cm. entire tissue processed.,section shows multiple linear cores with a neoplasm arranged in sheets showing polygonal cells with round to oval nuclei increased nuclear cytoplasmic ratio occasional eosinophilic nucleoli and moderate amount of clear to eosinophilic cytoplasm.,fnac from left axillary node poorly differentiated malignancy.the possibilities considered are:1) malignant lymphoproliferative disorder.2) poorly differentiated metastasis.report on ihc to follow.
MR1716871,left breast lump p o carcinoma breast.,biopsy from left breast lump.,received 5 greywhite to greybrown linear cores measuring 1.2 to 1.3cm. entire tissue processed.,section from the breast parenchyma with round to oval hyperchromatic nuclei with abundant eosinophilic cytoplasm. adjacent stroma shows inflammatory infiltrates composed lymphocytes and epitheloid cells forming granuloma. mitosis 4 5 hpf.,left breast lump:infiltrating ductal carcinoma grade 2.mbr score (3+2+1) : 6 9.
MR1716879,mass left breast carcinoma breast.,left breast mass biopsy.,received multiple grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section shows cores of breast parenchyma harboring infiltrating lesion arranged in sheets cords and tubules. the lesional cells are round to oval cells having high pleomorphic hyperchromatic nuclei and scant cytoplasm. intervening stroma shows desmoplasia and lymphoplasmacytic infiltration. mitosis 6 7 10hpf.,left breast mass biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1716905,right breast mass carcinoma breast.,biopsy from right breast mass.,received 1 fragmented grey white to grey brown linear cores measures 1.2cm. entire tissue processed.,section shows cores of breast parenchyma harboring infiltrating lesion composed of spindle to oval cells. cells exhibit mild to moderate nuclear pleomorphism having dispersed chromatin and moderate cytoplasm lesion is showing many capillaries lined by plump endothelial cells large areas of hemorrhage noted. mitosis 4 5 10hpf.,biopsy from right breast mass:atypical cells seen in tubules and sheets highly suspicious of malignancy.suggest excision of the lump for further confirmation.
MR1716949,left breast lump possibility of carcinoma breast.,left breast lump core biopsy.,received multiple fragmented grey yellow to grey brown linear cores measures 0.3 to 0.8cm. entire tissue processed.,section sows tumor cells in nests cords and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6( 3+2+1).
MR1716951,left breast lump p o carcinoma breast.,biopsy from left breast.,received multiple grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section studied from tissue cores of breast show tumor arranged in diffuse sheets. the tumor cells are round to oval with moderate cytoplasm and pleomorphic hyperchromatic nucleus. the tumor cells are invading into adjacent fibrous stroma. mitotic activity is seen.,biopsy from left breast:invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9.tubule formation 3nuclear pleomorphism 2mitotic activity 2 7 9
MR1716979,right breast lump p o carcinoma breast.,biopsy from right breast.,received multiple grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section studied from linear cores of breast shows tumor arranged diffuse sheets. the tumor cells are round to oval with moderate cytoplasm with pleomorphic hyperchromatic nuclei few showing intranuclear inclusion. admixed with these tumor cells areas of mucin are seen.,biopsy from right breast:invasive carcinoma with mucinous areas.grade 2.modified bloom richardson score is 6 9.tubule formation 3nuclear pleomorphic 2mitotic activity 1 6 9
MR1717009,right breast lump possibility of carcinoma breast.,biopsy from right breast lump,received grey white to grey brown linear cores measures 1.2 1.5cm. entire tissue processed.,section studied from breast linear cores show tumor arranged in diffuse sheets. the tumor cells are spindle cells with scant to moderate cytoplasm with pleomorphic hyperchromatic nucleus. few pleomorphic bizarre atypical cells are seen. mitotic activity is seen.,biopsy from right breast lump :spindle cell neoplasm (intermediate to high grade )
MR1717034,left sided breast lump carcinoma breast.,biopsy from left sided breast.,received grey white to grey yellow linear cores measures 1.5 to 1.8cm. entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged as tubules and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclear conspicuous nucleoli and moderate cytoplasm.,biopsy from left breast:invasive ductal carcinoma.modified bloom richardson score is 7 9 grade 2tubule formation : 3nuclear pleomorphism: 2mitotic figures : 2 7 9
MR1717101,left breast lump possibility of carcinoma breast,left breast lump core biopsy:,received 5 grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section shows diffuse sheets and nests. individual cells have hyperchromatic moderate to marked pleomorphic nuclei and moderate amount of cytoplasm. brisk mitosis is seen.,left breast lump core biopsy :invasive ductal carcinoma grade 3. modified bloom richardson score is 9(3+3+3).
MR1717120,case of left breast carcinoma.,a) left breast conserving surgery.b) left axillary dissection.,a) received lumpectomy specimen measures 4.5x4.5x3cm.skin ellipse measures 4x0.8. cut surface shows a grey white areas measures 3x2x1cm.distance from margins :superior : 0.6cm.inferior : 1.5cm.medial : 0.5cm.lateral : 1cm.deep : abutting 0.2cm.b) received one fibrofatty tissue measuring 9x7x1cm. largest lymph node measures 1x0.5x0.5cm. cut surface fatty infiltration.p e.,wide excision post lumpectomy.tumor bed :maximum section shows fibrous necrosis focal collection of lymphoplasmacytic cells. no evidence of residual viable tumor present.surrounding breast parenchyma shows adenosis and fibrocystic disease.all resected margins are free of tumor.axillary lymph nodes 17 nodes no deposits of tumor present.,wide excision lumpectomy post lumpectomyno residual viable tumor present.post lumpectomy changes present with fibrosis and lymphoplasmacytic infiltrate.all resected margins are free of tumor.lymph nodes :17 nodes no deposits of tumor.
MR1717152,left breast lump possibility of carcinoma breast.,left breast lump biopsy.,received 4 gray white to gray brown linear cores measure 0.8 1.2cm. entire tissue process.,section shows cores of breast parenchyma with an infiltrating lesion arranged in nests and cords. cells have and moderately pleomorphic hyperchromatic nuclei and amount of cytoplasm. areas of hemorrhage noted. stromal desmoplasia noted.,left breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score 6 9 (3+2+1).
MR1717183,breast lump possibility of carcinoma breast.,right breast lump biopsy.,received 4 gray white to gray brown linear cores measure 1 1.2cm. entire tissue process.,section shows cores of breast parenchyma with an infiltrating lesion arranged amp sheets nests and glands. cells lining these structures have moderately pleomorphic hyperchromatic nuclei and moderate to abundant cytoplasm. adjacent stroma show desmoplasia and dense lymphocytic infiltration.,right breast lump biopsy. invasive ductal carcinoma grade2.modified bloom richardson score 7 9. (3+2+2)
MR1717184,right breast lump carcinoma breast.,biopsy from right breast.,received 3 grey white to grey brown linear cores measures 0.8 to 1.2cm. entire tissue processed.,section shows fibrocollagenous stroma with ducts lined by single layer. the cells are round to oval hyperchromatic nuclei moderate cytoplasm few vesicular nuclei with prominent nucleoli. similar individual cells scattered with intracytoplasmic vacuolations.mitotic figures discerned.,biopsy from right breast:infiltrating ductal carcinomamodified bloom richardson score is 6(2+2+2).
MR1717185,left breast lump carcinoma breast.,biopsy from left breast.,received 4 gray white to gray brown linear cores measure 1.2 1.4cm. entire tissue process.,section studied from linear breast cores harbor tumor arranged in diffuse sheets. the tumor cells round to oval moderate cytoplasm pleomorphic hyperchromatic nucleus invading stroma focal area shows comedo pattern ductal carcinoma in situ. stroma shows mild inflammatory infiltrate.,biopsy from left breast :invasive ductal carcinoma grade ii ductal carcinoma in situ component seen. modified bloom richardson score is 7 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 .......... 7 9 ..........
MR1717207,left breast lump possibility of carcinoma breast,biopsy from left breast.,received 4 gray white to gray brown linear cores measure 1 1.2cm. entire tissue process.,section studied from linear breast cores harbor tumor arranged in sheets. the tumor cells are round to oval with moderate cytoplasm pleomorphic hyperchromatic nucleus. tumor cells invading stroma along with inflammatory infiltrate.,biopsy from left breast:invasive ductal carcinoma grade 2. modified bloom richardson score is 6 9.tubule for formation : 3nuclear pleomorphism : 2mitotic figures : 1 ......... 6 9 ..........
MR1717243,left breast lump possibility of carcinoma breast.,biopsy from breast.,received 4 grey white to grey brown linear cores measures 1.2 to 1.4cm. entire tissue processed.,section section shows linear breast cores harbors tumor arranged in sheets .the tumor cells are round to oval with pleomorphic hyperchromatic nucleus invading stroma and adjacent adipose tissue. admixed inflammatory cells are seen along with areas of necrosis seen.,biopsy from left breast:infiltrating ductal carcinoma grade 2modified bloom richardson score is 6 9.tubule formation :3nuclear pleomorphism :2mitotic figures :1 6 9
MR1717331,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received 3 grey white to grey yellow linear cores measures 0.8x1.2cm. entire tissue processed.,section from breast parenchytma shows a lesion arranged in sheets and nests. the cells forming the lesion are round to oval hyperchromatic nuclei with moderate amount of cytoplasm. adjacent stroma shows mild inflammatory infiltrates composed of lymphocytes and plasma cells. mitosis 2 3 10hpf.,biopsy from left breast:infiltrating ductal carcinoma grade 2modified bloom richardson score (3+3+1) 7 9.
MR1717342,carcinoma right breast post op right chest wall mass recurrence.,biopsy from right chest wall mass.,received multiple gray white linear cores measures 0.2 0.6cm. entire tissue processed.,section shows cores of fibromuscular tissue harboring an invasive neoplasm in nests glands and cords. the cells show moderate cytoplasm round to oval moderately pleomorphic nuclei with hyperchromasia. stroma appears desmoplastic and fibrous.,biopsy from right chest wall mass:features favorr recurrent carcinoma in known case of carcinoma breast.
MR1717397,known case of carcinoma cervix,biopsy from left breast lump,received 5 grey white linear cores measures 0.7 1cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in nests and sheets. cells are large round to oval hyperchromatic nucleus with prominent nucleoli and moderate cytoplasm. areas of necrosis is noted.,biopsy from left breast lump:invasive carcinoma metastatic primary.
MR1717407,left breast lump with liver amp skeletal metastasis,left breast core biopsy.,received 6 gray white linear cores measure 0.8 1 cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests amp tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1717417,left breast lump p o carcinoma breast.,left breast lump core biopsy.,received multiple grey white to grey brown linear cores measures 0.5 to 1.2 cm. entire tissue processed.,section shows tumor cells in nests and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:individual ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1717466,left breast lump possibility of carcinoma breast.,trucut biopsy from left breast lump.,received 4 gray white to gray yellow linear cores measure 1 1.2cm. entire tissue processed.,section shows 4 linear cores of breast parenchyma harboring an infiltrating lesion arranged in sheets and cords with areas of necrosis. the lesional cells have highly pleomorphic round to irregular hyperchromatic nucleus few with prominent nucleoli and moderate cytoplasm.,trucut biopsy from left breast lump. invasive ductal carcinoma (nos) grade iii modified bloom richardson score 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 .............. 8 9 ..............
MR1717517,right breast lump possibility of carcinoma breast,biopsy from right breast.,received 4 grey white to grey yellow linear cores measures 0.8 to 1.2cm. entire tissue processed.,section from the breast parenchyma harboring a infiltrating neoplasm arranged in islands and nests. the cells forming the lesion are round to oval hyperchromatic nuclei with abundant cytoplasm abundant stroma shows lymphoplasmacytic infiltration . mitotic figures discerned,biopsy from right breast:invasive carcinoma nuclear grade 2 (papillary features)
MR1717531,left breast lump carcinoma left breast..,biopsy from left breast.,received 3 grey white to grey yellow linear cores measures 0.5 to 1.4cm. entire tissue processed.,section from the breast parenchyma harbouring a infiltrating neoplasm arranged in sheets nests. the cells are pleomorphic round to oval hyperchromatic nuclei few with prominent nucleoli. mitotic figures discerned.,biopsy from left breast:infiltrating ductal carcinoma grade 2modified bloom richardson score (3+3+1)7 9
MR1717544,right breast mass carcinoma breast.,right breast lump core biopsy.,received 4 grey white to grey yellow linear cores measures 0.5 to 1cm. entire tissue processed.,section sows core of tissue infiltrated by tumor cells in nests and cords . individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1717558,right breast lesion malignant,biopsy from right breast lesion.,received multiple grey white to grey yellow linear cores measures 0.5 to 1.8cm. entire tissue processed.,linear cores of fibrofatty tissue infiltrated by a neoplasm arranged in cords and trabeculae. the neoplastic cells are round to polygonal have eccentrically placed hyperchromatic nucleai and moderate cytoplasm. crush artefact noted.,biopsy from right breast lesion:poorly differentiated malignancy. invasive carcinoma with lobular features. plasma cell neoplasm.suggest ihc.
MR1717562,left breast mass carcinoma breast.,biopsy form left breast mass .,received 4 gray white to gray yellow linear cores measures 0.4 0.6cm. entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged as cords and clusters. the neoplastic cells are round to polygonal have vesicular nucleus conspicuous nucleoli and moderate cytoplasm. the intervening stroma is fibrous.,biopsy form left breast mass .invasive ductal carcinoma modified bloom richardson score 6 9 .grade2tubule formation : 3nuclear pleomorphism :2mitotic figures :1 6 9
MR1717582,right breast mass fibroadenoma carcinoma breast.,right breast mass core biopsy.,received 5 grey white linear cores 0.3 to 0.6cm. entire tissue processed.,section shows cores of tissue with hyperplastic ductules lined by tall columnar epithelium and myoepithelial cells. stroma shows fibrocollagenous tissue and few lymphocytes. no atypia is seen.,right breast mass core biopsy:features suggestive of benign proliferative breast disease.negative for invasive malignancy.
MR1717583,right breast carcinoma breast.,biopsy from right breast.,received 4 grey white to grey brown linear cores measures 0.3 to 0.5cm. entire tissue processed.,section shows linear cores of tissue harboring proliferating capillaries and mixed inflammatory cell infiltrate with predominance of plasma cells. a few ducts are noted surrounded by plasmacytic inflammatory cell infiltrate.,biopsy from right breast: inflammatory lesion with predominance of plasma cellskindly follow up and suggest repeat biopsy if deemed necessary.needs correlation with imageology.
MR1717596,right breast speculated lesion carcinoma breast.,right breast core biopsy.,received four grey white to grey yellow linear cores measures 0.5 to 1cm. entire tissue processed.,section sows core of tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1717621,lump in left breast carcinoma breast..,left breast lump biopsy.,received 4 grey white linear cores measures measures 1 to 1.2 cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1717623,lump in right breast carcinoma breast.,biopsy from right breast lump.,received three grey white linear cores measures 0.3 1 cm. entire tissue processed.,section shows tumor cells in differentiated sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1717659,known case of carcinoma left breast post mrm.left chest wall lesion recurrence.,left chest wall lesion core biopsy (post op left breast carcinoma).,received multiple grey white to grey yellow linear cores measures 0.6 to 0.8cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left chest wall lesion core biopsy (post op left breast carcinoma) :suggestive of recurrent carcinoma in known and treated case of carcinoma left breast.
MR1717718,left breast mass carcinoma breast.,left breast lump core biopsy.,received 4 grey white linear cores 0.4 to 1cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets and nests . individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1717731,lump right breast.,lumpectomy with wide excision.,received lumpectomy specimen measures 5.5x5x3cmcut surface cystic hemorrhagic lesion papillary excrescences measures 1.5x1.5x1.3cm.distance from margin:superior margin : 1.5cminferior margin : 1cmmedial margin : 2.3cmlateral margin : 1.5cmdeep margin : 0.9cm,section shows pleomorphic cells with pleomorphic vesicular nucleus and eosinophilic cytoplasm. the tumor is arranged in papillary configuration with fibrovascular core. modified bloom richardson score is 4 9 nuclear grade 1.tubule formation : 2 nuclear pleomorphism : 1mitotic activity : 1lymphovascular invasion : not presentductal carcinoma in situ : not presentperineural invasion : not presentresected margins superior margin : free of tumorinferior margin : free of tumormedial : free of tumorlateral margin : free of tumor,lumpectomy with wide excision:papillary carcinomanuclear grade ilymphovascular invasion : not presentductal carcinoma in situ : not presentall resected margins are free of tumor
MR1717778,left breast mass fibrocystic disease carcinoma breast.,biopsy from left breast.,received 3 grey white to grey yellow linear cores of measures 1 to 1.2cm. entire tissue processed.,section shows cores of breast tissue with few dilated ducts atypical hyperplasia. there are markedly desmoplastic strom round clusters of atypical cells . the cells are pleomorphic to spindled amount with moderate cytoplasm and hyperchromatic nuclei with moderate pleomorphism. scattered lymphocytic infiltration noted.,biopsy from left breast:suspicious of malignancy against a background of fibrocystic disease suggest repeat biopsy.
MR1717785,right axillary malignant breast.,trucut biopsy right breast axillary mass.,received multiple grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue processed.,h amp e section shows linear cores of fibrotic tissue harboring an infiltrating neoplasm arranged in cords and nests. the lesional cell have pleomorphic round to irregular hyperchromatic nucleus and moderate cytoplasm. bizarre nuclear forms noted with brisk mitoses and karyorrhectic debris. no definite breast parenchyma noted.,trucut biopsy right breast axillary mass:invasive carcinoma (nuclear grade 2)
MR1717792,right breast mass carcinoma breast.,right breast mass core biopsy,received 4 grey white to grey brown linear cores measures 1.2 to 1.4cm. entire tissue processed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast mass core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1717805,right breast mass carcinoma breast.,biopsy from right breast mass.,received 3 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows cores of fibro adepose tissue harboring an invasive neoplasm cells in sheets and nests. the cells show moderate eosinophilic cytoplasm pleomorphilic hyperchromatic nuclei. stroma is desmoplastic.,biopsy from right breast mass:invasive ductal carcinoma nos. grade 2.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic activity 2 7 9
MR1717821,carcinoma right breast post op.,right chest wall lesion.,received multiple grey white linear cores measures 1 to 1.2cm. entire tissue processed.,.sectionsfrom the linear core submitted shows infarction with occasional atypical cell,infarction status post operative:right chest wall lesion
MR1717826,left breast 3 4 o clock position.,biopsy from left breast lesion 3 4 o clock position.,received multiple grey white to grey brown linear cores measures 0.6 to 0.8cm. entire tissue processed.,section shows cores of breast parenchyma with a lesion showing ductal carcinoma in situ of cribriform type and with comedonecrosis.cells have oval hyperchromatic nuclei and moderate cytoplasm. areas of mucin noted.,biopsy from left breast lesion 3 4 o clock position:intermediate to high grade ductal carcinoma in situ and focal mucinous areas.note:larger tissue may be needed to exclude invasive focus.
MR1717832,right breast mass carcinoma right breast.,biopsy from right breast.,received multiple grey white to grey yellow linear cores 1 to 1.2cm. entire tissue processed.,section shows 4 linear cores of breast parenchyma harboring an infiltrating neoplasm arranged in cords and singly scattered forms along with occasional foci of ductal carcinoma in situ. dense mononuclear infiltrate is noted.,biopsy from right breast mass:features are suggestive of invasive ductal carcinoma ( nuclear grade 2).
MR1717835,mass in right breast carcinoma breast.,biopsy from right breast.,received 3 gray white to gray yellow linear cores measures 0.9 1.9cm. entire tissue processed.,section shows cores of fibro adipose tissue harboring an invasive neoplasm in sheets and nests with moderate eosinophilic cytoplasm hyperchromatic nuclei with moderate nuclear pleomorphism. stroma is dismoplastic with necrosis.,biopsy from right breast. invasive ductal carcinoma (nos) grade 2.modified bloom richardson score is 7 9tubular formation 3nuclear pleomorphism 2mitotic activity 2 7 9
MR1717899,complex cyst in right breast suspicious of carcinoma.,right breast mass core biopsy.,received multiple fragmented grey white to grey yellow cores measures 0.2 to 0.3 cm. entire tissue processed.,section shows tumor cell in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast mass core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 7(3+2+2).
MR1717903,left breast mass carcinoma breast,left breast mass core biopsy.,received 4grey white to grey brown linear cores measures 1 to 1.2 cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets nests and tubules . individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1717908,right breast mass carcinoma breast.,biopsy from right breast.,received multiple grey white to grey yellow linear cores measures 1.1 to 1.2cm. entire tissue processed.,section shows fibro adepose tissue harboring an invasive neoplasm in sheets and nests with moderate eosinophilic cytoplasm. moderate nuclear pleomorphism and prominent nucleoli. stroma is desmoplastic.,biopsy from right breast:invasive ductal carcinoma nos grade 2.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic activity 2 7 9
MR1717949,carcinoma right breast post nact.,a) sentinel lymph nodes.b) breast conservative surgery.c) axillary nodal clearance.,a) received fibrofatty tissue measures 2x1x0.8cmisolated 2 lymph nodes largest measures 0.9x0.8x0.7cm. entire tissue processed.b) received fibrofatty tissue measures 4x5x3cmskin ellipse measures 2x0.8xcmcut surface shows a grey white firm lesion measures 1x1x0.8cm.distance from margins: superior margins : 1cminferior margins : 1cmright lateral margin: 2cmleft lateral margin :1.5cmdeep margin : 2cm.c) received fibrofatty tissue measures 4x3x2cm,a) sentinel lymph nodes:two nodes isolated one node in frozen section shows micro metastatic deposits of tumor invasive ductal carcinoma viable tumor at the capsule out of 2 nodes. no perinodal spread present.b) breast conservative surgery:the section show fibrotic areas atrophic ducts. no residual viable tumor present.post therapy changes. surrounding ducts show adenosisresected margins : superior margin: free of tumor.inferior margin :free of tumor.medial margin :free of tumor.lateral margin :free of tumor.deep margin :free of tumorc) axillary nodal clearance:9 nodes . no deposit of tumor.,b) breast conservative surgery:no residual viable tumor all resected margins are free of tumora)sentinel lymph nodes:0ne node in frozen section shows micro metastasis of invasive ductal carcinoma of 2 nodes 1 2perinodal spread not present.c)axillary lymph node dissection:9 nodes no metastatic deposit of tumor.0 9
MR1717985,left breast mass carcinoma breast,left breast mass core biopsy,received multiple grey white to grey yellow linear cores measures 1.1 to 1.2 cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6 (3+2+1).
MR1718002,left breast mass carcinoma breast.,biopsy from left breast mass.,received multiple grey white linear cores measures 0.7 to 1cm. entire tissue processed.,section shows linear tissue cores showing presence of ducts and acini showing focal lobular arrangement. there is luminal layer of low columnar to cuboidal epithelial cells and abluminal myoepithelial layer. few acini are dilated. focal apocrine metaplasia and micropapillary patterns are noted. there is dense intervening fibrocollagenous connective tissue stroma.,biopsy from left breast mass:features are suggestive of benign proliferative breast disease.no evidence of malignancy in the sections studied.
MR1718052,right breast mass carcinoma breast.,right breast mass core biopsy.,received multiple grey white to grey brown linear cores measures 0.5 to 1 cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei moderate amount of cytoplasm.,right breast mass core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1718104,carcinoma right breast post lumpectomy.,a)wide excision of lumpectomy.b) right axillary lymph node dissection.,a) wide local excision of right breast measures 5x4x2cm.skin ellips measures 3x0.8 cm on serial sectioning vague grey yellow areas noted altogether 0.8x0.5x0.5cm.distance from margins.superior margin: 0.8cminferior margin :2cmmedial margin :2.5cmlateral margin :1.5cmdeep margin :2.5cmb) received fibrofatty tissue measures 5x4x2cm. large lymph node measures 1.5x0.8x0.6cm. cut surface grey brown.,a) wide local excision post lumpectomyresidual tumor is present invasive ductal carcinoma are measuring 0.8x0.5x0.5cmtubule formation 2mitotic figures 2anaplasia 2modified bloom richardson score is 6 9.nuclear grade iilymphovascular invasion not presentperineural invasion not presentrevised marginssuperior margin: free of tumorinferior margin :free of tumormedial margin :free of tumorlateral margin : free of tumordeep margins : free of tumor b) right axillary lymph node. 8 nodes no deposit of tumor.,a)wide excision of lumpectomy:residual tumor present measures 0.8x0.7x0.5cm.invasive ductal carcinoma.nuclear grade ii.lymphovascular invasion not present.perineural invasion not present.all resected margins are free of tumor.b) right axillary lymph node dissection:8 nodes. no deposit of tumor.
MR1718116,right breast lump carcinoma breast,right breast lump core biopsy,received multiple grey white linear cores measures 0.8 1cm. entire tissue processed.,section shows tumor cells in tubules nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy :invasive ductal carcinoma grade 1. modified bloom richardson score is (2+2+1).
MR1718171,left breast lump carcinoma breast fibrocystic changes.,left breast lump core biopsy.,received 5 grey white linear cores measures 1 1.2cm. entire tissue processed.,section shows cores with fibrocollagenous tissue and few ductules lined by epithelial and myoepithelial cells. no atypia is seen.,left breast lump core biopsy :shows benign breast tissue.negative for malignancy.
MR1718174,carcinoma left breast.,left chest wall mass lesion.,received multiple grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section shows multiple linear cores of fibrocollagenous tissue with chronic inflammatory infiltrate. focal hyalinisation is noted. focal aggregates of plasma cells are seen. no atypical cells are noted.,left chest wall mass lesion:features are suggestive of chronic inflammatory lesion.no evidence of malignancy.
MR1718235,left breast lump carcinoma breast.,biopsy from left breast.,received 5 grey white to grey brown linear cores measures 0.2 to 1.2cm. entire tissue processed.,section shows multiple linear cores with an infiltrative neoplasm arranged in sheets. the cells show moderate nuclear pleomorphism with round to oval nuclei occasional conspicuous nucleoli and moderate amount of cytoplasm mitotic figures are discerned. surrounding stroma shows dense plasmacytic inflammation.ihc pck positive in tumour cells,biopsy from left breast:suggestive of poorly differentiated carcinoma against a background of plasma cell mastitis..
MR1718240,left breast mass carcinoma breast.,left breast mass.,received 3 grey white to grey yellow linear cores measures 0.7 to 1cm. entire tissue processed.,section from the breast parenchyma shows infiltrating lesion arranged in sheets nests. the cells forming the lesion are round to oval with hyperchromatic nuclei abundant eosinophilic cytoplasm. few cells show vesicular nuclei with prominent nucleoli. adjacent stroma shows lymphoplasmacytic infiltration.,left breast mass:infiltrating ductal carcinoma grade 2.modified bloom richardson score is 6 9.tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1718300,left breast lump carcinoma.,biopsy from left breast lump.,received 3 grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue processed.,section shows linear cores of tissue fragments harboring a neoplastic lesion arranged in sheets. the cells have high n:c ratio with round to oval pleomorphic nuclei and moderate cytoplasm. intervening area shows hyalinisation and fibrosis.,biopsy from left breast lump:invasive carcinoma grade ii.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 3mitotic activity 1 7 9
MR1718326,left breast lump,biopsy from left breast lump.,received 4 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows cores of breast tissue harbouring an invasive neoplasm in sheets and nests. the cells show moderate eosinophilic cytoplasm hyperchromatic nuclei with moderate pleomorphism and prominent nucleoli. extensive peritumoral lymphocytes noted.,biopsy from left breast lump:invasive carcinoma( nst)modified bloom richardson score is 3+2+2 7 9.
MR1718346,right breast lump possibility of carcinoma breast,biopsy from right breast.,received 4 grey white linear cores measures 1 to 1.2 cm. entire tissue processed.,section shows cores of fibro adipose tissue harboring an invasive neoplasm seen in nests and tubules .the cells show abundant eosinophilic granular cytoplasm nuclei with moderate pleomorphiism.the stroma is desmoplastic with foci of inflammation.,biopsy from right breast:invasive carcinoma (nst) with apocrine features grade ii.modified bloom richardson score is 2+2+2 6 9.
MR1718357,right breast lump carcinoma breast.,biopsy from right breast lump,received 4 grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section shows multiple linear cores with a tumor arranged in the form of nests cords and glands . the tumor cells show moderate nuclear pleomorphism with conspicuous nucleoli. many mitotic figures are seen. perineural invasion is noted.,biopsy from right breast lump:invasive ductal carcinoma grade iimodified bloom richardson score is 7 9 (2+2+3).
MR1718374,known case of carcinoma breast lump.,right side chest wall lesion.,received 4 linear grey white cores measures 1.2 to 1.4cm. entire tissue processed.,section shows cores of fibrocollagenous tissue harboring an invasive neoplasm in sheets and cords composed of cells with moderate eosinophilic to clear cytoplasm pleomorphic nuclei with moderate eosinophilic to clear cytoplasm pleomorphic a nuclei with moderate atypia and prominent nucleoli stroma is desmoplastic.,right side chest wall lesion biopsy :suggestive of recurrence carcinoma in a known case of carcinoma breast.
MR1718395,known case of carcinoma breast.,biopsy from right lung mass.,received multiple grey white linear cores measures 0.7 to 1.2cm. entire tissue processed.,section shows multiple linear cores of tissue harboring a neoplasm arranged in cords and vague nests along with extensive areas of necrosis. the tumor cells have irregular hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm. marked nuclear pleomorphism is noted. surrounding stroma shows karyorrhectic debris.,biopsy from right lung mass:features are suggestive of poorly differentiated carcinoma probably metastatic from breast.
MR1718408,right breast lump carcinoma breast.,biopsy from right breast lump.,received 3 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section shows cores of fibrocollagenous tissue harbouring an invasive neoplasm in sheets and tubules . the cells show moderate eosinophilic cytoplasm hyperchromatic nuclei with moderate pleomorphism and increased mitosis . areas of necrosis present.solid type ductal carcinoma in situ noted. stroma is desmoplastic.,biopsy from right breast lump:invasive carcinoma (nst)modified bloom richardson score is 3+2+3 8 9
MR1718431,right breast lump p o carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords trabecular and in sheets. the cells have round to oval pleomorphic nuclei with moderate amount of cytoplasm. mitosis are seen. areas of hyalinisation are noted.,biopsy from right breast lump invasive ductal carcinoma grade ii.modified bloom richardson score is 7 9.tubular formation 3 nuclear pleomorphism 2mitotic activity 2 7 9
MR1718462,carcinoma right breast.,a) right breast right lumpectomy(post nact).b) right axillary lymph nodes.,a) received lumpectomy specimen measures 8.5 x 6 x 2.5 cm.serial section identified grey white lesion measures 2.5x2x1.5 cmdistances from different margins:superior margin : 1.5 cminferior margin : 2 cmmedial margin : 3 cmlateral margin : 1.5 cmrepresentative sections are submitted.b) received fibrofatty tissue measures 9x5x3 cmmultiple lymph nodes identified largest lymph node measures 2x2x1 cm cut surface shows grey brown.,section shows residual tumor cells in diffuse sheets nests and sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular or perineural invasion is not seen.,a) right breast right lumpectomy(post nact) :residual invasive ductal carcinoma grade 2. tumor measures 2.5 cm in greatest dimension. lymphovascular invasion is not seen. perineural invasion is not seen. all margins of resection are free of tumor.b) right axillary lymph nodes:fourteen lymph nodes are identified negative for malignancy (0 14).
MR1718470,right breast lump possibility of carcinoma breast.,right breast core biopsy.,received 4 multiple grey white to grey brown linear cores measures 1 to 1.3 cm. entire tissue processed.,section sows tumor cells in diffuse sheets and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1718471,left breast lump carcinoma breast.,left breast core biopsy.,received 6 grey white to grey brown linear measures 1 x 1.2 cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in tubules and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy :invasive ductal carcinoma grade 1 modified bloom richardson score is 5(2+2+1).
MR1718484,carcinoma right breast,a)right breast axillary sentinel lymph nodeb) right breast lump,a) received multiple fibrofatty tissue measures3.5x2x0.5cm. largest lymph nodes measures 2.5x1.5x0.5cm. cut surace faty infiltrating isolated 3 lymph nodes.b) received in : formalin procedure : mastectomy laterality : right total dimensions : medial to lateral :21cm superficial to deep :4cm superior to inferior : 14cmskin ellipse :11.5x7cmnipple : normal scar surgical defect : not seengrey white lesion : single grey white lesion measures : 3x3x2.5cm cystic areas measures 0.2 to 0.4cm. location grey white lesion : upper outer quadrant : margins of tumor : circumscribed deep margin : 2cmmuscle : absentadjacent breast : fibrofatty tissue,section from the breast parenchyma with a lesion arranged in papillae in solid sheets and cribriform. the cells are moderate cytoplasm and prominent nucleoli comedo necrosis seen.,a)right breast axillary sentinel lymph node:3 lymph nodes identified : one shows tumor deposit in sub capsular regionb) right breast lump:extensive ductal carcinoma in situ papillary solid and cribriform patternfoci of invasion measures 0.5cmductal carcinoma in situ measures 2.5cmlymphovascular invasion is presentperineural invasion not identifiedposterior margin is free of tumornipple and areola is unremarkable.
MR1718485,right breast lump possibility of carcinoma breast.,right breast biopsy,received 4 grey white linear cores measures 1.1 to 1.2cm. entire tissue processed.,section shows linear cores of tissue infiltrated by sheets and irregular nests comprising of atypical oval cells with round to oval pleomorphic hyperchromatic nuclei conspicuous nucleoli and scanty cytoplasm. stroma show extensive lymphoplasmacytic infiltrate and hyalinisation. mitotic figures 4 5 10 hpf.,right breast biopsy:invasive ductal carcinoma grade iimodified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9with extensive lymphocytic infiltrate.the possibility of intramammary node harbouring tumor deposits cannot be ruled out.please correlate with mammographic findings.
MR1718509,left breast lump p o carcinoma breast.,left breast lump biopsy.,received multiple grey white to grey yellow linear cores measures 0.8 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords. the cells have pleomorphic round to oval nuclei with scant cytoplasm. areas of hyalinization seen.,left breast lump biopsy:invasive ductal carcinoma grade ii.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 3mitotic activity 1 7 9
MR1718512,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 4 grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue processed.,section sh9ows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords trabecular and in sheets. the cells are pleomorphic with round to oval vesicular nuclei prominent nucleoli and moderate cytoplasm. areas of necrosis and hyalinisation.,left breast lump biopsy:invasive ductal carcinoma grade ii modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphic: 3mitotic figures : 1 7 9ductal carcinoma in situ comedonecrosis seen.
MR1718555,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white to grey brown linear cores measures 1.2x1.4cm. entire tissue processed.,section shows linear cores of breast parenchyma harbouring a neoplastic lesion arranged in cords trabecular and singly scattered. the cells are pleomorphic with round to oval vesicular nuclei prominent nucleoli and moderate cytoplasm. areas of hyalinisation seen. areas of hemorrhagic seen.,left breast lump biopsy:invasive carcinoma grade iii 8 9.tubule formation : 3nuclear pleomorphic: 3mitotic figures : 2 8 9
MR1718557,right breast lump p o carcinoma breast.,biopsy from right breast lump.,received 4 greywhite to greybrown linear cores measuring 1 to 1.2cm. entire tissue processed.,section show linear cores of tissue with infiltration lesion in the fibrofatty tissue. the cells are arranged in sheets with round to oval hyperchromatic nuclei inconspicious nucleoli and scant amount of cytoplasm.mitotic figures discerned. crush artefacts noted.,biopsy from right breast lump:hematolymphoid malignancy.suggest ihc.
MR1718568,right breast lump.,right breast lump core biopsy.,received three grey white linear cores measures 0.6 to 0.8cm. entire tissue processed.,section shows cores of tissue infiltrated by ductal carcinoma in situ.,right breast lump core biopsy :shows ductal carcinoma in situ of solid pattern with intermediate nuclear grade is seen. invasive carcinoma cannot be ruled out.suggest repeat biopsy of excision of the lump for further confirmation of invasive component.
MR1718584,let axillary node deposit.,left axillary node core biopsy.,received multiple grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left axillary node core biopsy:positive for malignancy.suggestive of metastatic carcinoma most possible from breast.
MR1718608,right breast lump.,right breast lump core biopsy.,received 3 mucinous cores measures 0.4 to 0.6cm. entire tissue processed.,section tissue showing few tumor cells in small nests lying in pools of extracellular mucin. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy:suggestive of mucinous carcinoma.
MR1718615,case of right breast carcinoma.,a) right breast wide excision lumpectomyb) blue + hot nodec) non blue non hot noded) wide excision of skin lesion,a) received skin covered fibrofatty tissue measuring 5.5x3x2.5cm.skin ellipse measures 4x1.2cmsurface shows scar measuring 1cmsection shows grey white lesion measures 1x0.8x0.8cm. no obvious tumor is noted.distance from margins:superior margin : 0.5cminferior margin : 0.3cmmedial margin : 1cmlateral margin : 1.2cmdeep margin :1.5cmsuperior and inferior margins show fibrosisb) received fibrofatty tissue measures 2x2x1cm. isolated 2 lymph nodes.largest node measures 0.4x0.4x0.4cm. c) received singly fibrofatty tissue measures 1x1x0.5cmisolated lymph node.d) received skin covered fibrofatty measures 7x4x2.5cm.skin ellipse measures 6.5x3.5cmsurface shows shows slightly discolored elevated area measuring 3.5x2.5x0.5cmdistance from margin:superior margin : 1.5cminferior margin : 2cmmedial margin : 0.8cmlateral margin : 0.9cmdeep margin :2cm,a)section studied show breast parenchyma with adenosis stromal fibrosis focal necrosis and inflammatory infiltrates . multinucleated giant cells seen. no residual tumor seen.d )section studied show skin with a lesion in reticular dermis arranged in small nests sheets predominantly around pilosebaceous units . lesion shows variable cellularity and pigmentation. cells have round to oval vesicular nuclei inconspicuous nucleoli and moderate amount of cytoplasm. no cellular atypia or mitosis noted . lesion is seen extending into subcutancous adipose tissue.,a) right breast wide excision lumpectomy post lumpectomyno residual tumor seen only adenosisall resected margins including deep are free of tumor.b) blue + hot node :four lymph nodes isolated all are free of tumor (0 4)c) non blue non hot node : single lymph node isolated free of tumor (0 1).d) wide excision of skin lesion of right arm dorsal aspect :intradermal nevus lesion measures 3.5x2.5x0.5cmall resected margin including deep are free.
MR1718672,known case of carcinoma breast.cerebral metastasis.,right fronto parietal craniotomy and surgical decompression of tumor.,received 2.5x2.5x2.5 cm globular grey white mass cut surface shows grey white.,section shows glial tissue exhibiting extensive necrosis and infiltration by clusters and islands of atypical cells having enlarged pleomorphic round to oval nuclei granular chromatin prominent nucleoli and moderate eosinophilic cytoplasm. pervascular arrangement of cells is noted in some areas. mitotic figures discerned 1 2 hpf. occasional large bizarre multi nucleate cells are noted.,right fronto parietal region :consistent with metastatic deposit in a known case of carcinoma breast.
MR1718674,right breast lump carcinoma breast.,biopsy from right breast lump.,received multiple grey white linear cores measures 1.2 to 1.4cm. entire tissue processed.,section shows cores of fibrocollagenous tissue with an invasive neoplasm in sheets and nests. the cells show moderate eosinophilic cytoplasm pleomorphic hyperchromatic nuclei and prominent nucleoli. areas of necrosis present. ductal carcinoma in situ with comedo necrosis noted. stroma is desmoplastic.,biopsy from right breast lump:invasive carcinoma nst.modified bloom richardson score is 7 9.tubular formation 2nuclear pleomorphism 2mitotic activity 3 7 9 ductal carcinoma in situ comedo type seen.
MR1718696,left breast lump p o carcinoma breast.,left breast lump core biopsy.,received multiple grey white to grey brown linear cores measures 0.7 to 1.1cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1718703,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple grey white to grey brown linear cores measures 0.6 to 0.8cm. entire tissue processed.,section shows cores of breast tissue with invasive neoplasm in sheets and linear cords and nests. the cells show moderate eosinophilic cytoplasm and eccentric placed nuclei. areas of hemorrhage and necrosis present. stroma is desmoplastic.,biopsy from left breast lump:invasive carcinoma nst grade 2. modified bloom richardson score is 7(3+2+2).
MR1718730,left breast lump carcinoma breast.,left breast lump biopsy.,received multiple grey white to grey yellow linear cores measures 1 to 1.2cm. entire tissue processed.,section shows linear cores of tissue harboring a neoplastic lesion arranged in cords trabecular and in sheets. the cells are pleomorphic with round to oval vesicular nuclei prominent nucleoli and abundant cytoplasm. intervening stroma shows lymphocytic infiltrate. areas of hyalinisation and fibrosis seen. areas of necrosis seen.,left breast lump biopsy:invasive ductal carcinoma nst grade ii.modified bloom richardson score is 6 9tubular formation 3nuclear pleomorphism 2mitotic activity 1 6 9 areas of necrosis seen.
MR1718733,right breast lump carcinoma breast.,biopsy from right breast,received 3 grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplasm lesion arranged in sheets . the cells have abundant cytoplasm with oval pleomorphic vesicular nuclei prominent nucleoli. brisk mitotic activity are seen. intervening stroma shows lymphocytic infiltrate . areas of hemorrhage seen.,biopsy from right breast lump:invasive ductal carcinoma nst grade iiimodified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1718734,known case of carcinoma right breast,biopsy from right breast.,received 4 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords and trabeculae. the cells are moderately pleomorphic with round to oval vesicular nuclei prominent nucleoli and moderate cytoplasm. areas of hyalinisation seen.,right breast lesion biopsy:invasive ductal carcinoma grade iimodified bloom richardson score 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures :1 6 9
MR1718740,carcinoma breast post op,biopsy from left lung mass.,received multiple grey white to grey brown linear cores measures 0.5 to 0.8cm. entire tissue processed.,section shows linear cores of tissue infiltrated by islands cords and nests of atypical cells with pleomorphic ovoid dark nuclei irregular nuclear margins and moderate eosinophilic cytoplasm few cells have round to oval dark nuclei and abundant pale granular eosinophilic cytoplasm. areas of necrosis seen. mitosis 5 6 10hpf . stroma is fibrotic and shows lymphoplasmacytic infiltrate.,biopsy from lung mass:suggestive of metastatic deposits in a known case of carcinoma breast.
MR1718746,right breast lump male breast carcinoma.,right breast lump core biopsy.,received multiple grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy:invasive ductal carcinoma grade 2.modified bloom richardson score is 6(3+2+1)
MR1718788,right breast lump carcinoma breast.,right breast lump biopsy.,received multiple grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section shows linear cores of tissue harboring a neoplastic lesion arranged to cords sheets. the cells are pleomorphic with round to oval vesicular nuclei prominent nucleoli and scant cytoplasm. intervening stroma shows hemorrhage hyalinisation and fibrosis.,right breast lump biopsy:invasive carcinoma nst.nuclear grade ii.
MR1718795,right breast lump malignant,biopsy from right breast.,received grey white to grey yellow linear cores measures 0.6 to 0.8cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords trabeculae. the cells are pleomorphic with round to oval vesicular nuclei prominent nucleoli and scant cytoplasm. ductal carcinoma in situ component is seen. areas of hyalinisation and fibrosis noted.,biopsy from right breast:invasive ductal carcinoma nst grade ii.modified bloom richardson score is 6 9tubule formation :3nuclear pleomorphic : 2mitotic figures : 1 6 9 ductal carcinoma in situ (cribriform type) with comedonecrosis.
MR1718813,lump right breast carcinoma breast.,biopsy from trucut biopsy right breast lump,received 4 grey white linear cores measures 1x0x2cm entire tissue processed.,section shows linear cores tissue cores harboring an inflltrative lesion arranged in cords tubules and discretely scattered cells exhibiting increased n c ratio nuclear hyperchromasia pleomorphism and variable amount of cytoplasm. the intervening stroma is dense fibrocollagenous . extensive necrosis is seen.,biopsy from trucut biopsy right breast lump:invasive carcinoma breast grade iimodified bloom richardson score (2+2+2).
MR1718829,carcinoma right breast post lumpectomy,right modified radical mastectomy.,received in : formalinprocedure : mastecmoy. laterality : righttotal dimensions : medial to lateral : 15cm superficial to deep : 4cm superior to inferior : 15cmskin ellipse : 10x6cmnipple :normal scar surgical defect :not seentumor : single lesion measuring : 2.5x2x2cm cut surface shows grey white scar with no definite lesion identified location of tumor : right upper outer quadrant margins of tumor : ill definite deep margin : 1.5cmmuscle : present measures 3x2cm.adjacent breast : fibrofatty tissue axillary tail : measures 6x5x3cmtotal number of nodes : 14 (specify if sentinel nodes sent )size of largest node :1x0.9x0.7cm cut surface grey white.,section from the breast parenchyma shows inflammation infiltrates composed of lymphocytic epithelial cells multi nucleate giant ells foamy macrophages. areas of necrosis. no evidence of malignancy identified.,tumor bed:no residual tumor present and tumor bed shows fibrosis necrosis hemorrhage ares lymphoplasmacytic infiltrate and foreign body giant cells.right breast right modified radical mastectomyno residual tumor carcinoma.posterior resection margin is free of tumor nipple and areola is unremarkable.lymph nodes 14 lymph nodes metastasis 6 (6 14)perinodal spread presentpathological state: yt0n2.summary:right modified radical mastectomy no residual tumor nodal metastasis 6 14 6 out of 14 shows nodal metastatic with perinodal extension
MR1718872,right breast lump p o carcinoma breast.,biopsy from right breast.,received multiple grey white linear cores measures 1 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged in tubular pattern and in clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. areas of necrosis and hemorrhage seen.,biopsy from right breast:infiltrating ductal carcinoma grade 2.modified bloom richardson score is 6 9.tubule formation 3nuclear pleomorphism 2mitotic activity 1 6 9
MR1718881,known case of carcinoma left breast,sacrum lesion,received 5 grey white linear cores measures 0.7 1cm. entire tissue processed.,section shows multiple linear cores with infiltrating neoplasm arranged in glands and diffuse scattered cells. the cells forming the lesion are round to oval with hyperchromatic nuclei with scant to moderate cytoplasm. adjacent stroma shows lymphoplasmacytic infiltrates.,sacrum lesion biopsy:metastatic carcinoma in a known case of carcinoma breast.
MR1718885,cerebellar tumor metastasis.,cerebellar tumor :,received multiple grey white soft tissue bits measures 3.5x3x2cm. entire tissue processed.,section studied shows tissue fragments harboring a predominantly necrotic lesion surrounding by congested vessels and areas of hemorrhage. the viable tumor cells are arranged is scattered clusters large nests and sheets of round to oval cells with moderate amount of eosinophilic cytoplasm and oval vesicular to hyperchromatic nucleus and prominent nucleoli. mitotic figures are 2 3 10hpf.,cerebellar tumor :metastatic carcinomatous deposits in known case of breast cancer.
MR1718918,right breast lump possibility of carcinoma.,biopsy from right breast lump.,received 4 grey white linear cores measures 1 t 1.5cm. entire tissue processed.,section shows multiple linear cores with an infiltrating tumor arranged in nests sheets and cords. the tumor cells show moderate to marked pleomorphism with round to oval nuclei prominent eosinophilic nucleoli and moderate amount of cytoplasm. few multi nucleated and bizarre forms and seen. focally few nests of cells are noted having abundant dense eosinophilic cytoplasm.,biopsy from right breast lump:invasive carcinoma ductal nst grade iii.modified bloom richardson score is 3+3+3 9 9
MR1718931,right breast lump possibility of carcinoma breast,biopsy from right breast.,received 3 grey white linear cores measures 1 to 1.2cm. entire tissue processed,section shows linear cores tissue harboring a neoplastic lesion arranged in islands and cords . the cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows desmoplasia . lymphovascular invasion is identified.,biopsy from right breast:invasive ductal carcinoma grade iimodified bloom richardson score is (3+2+1)6
MR1718944,right breast lump possibility of carcinoma breast,biopsy from right breast.,received 5 grey white linear cores measures 0.8 to 1cm. entire tissue processed,section shows linear cores of breast parenchyma with areas of ductal carcinoma in situ the cells having pleomorphic round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows fibrosis . areas of adenosis and occasional aggregates single scattered neoplastic cells in the stroma seen. lymphoplasmacytic infiltrate noted . lymphovascular emboli noted.,biopsy from right breast:predominant component of ductal carcinoma in situ with occasional suspicious focus of invasion.definitive invasion cannot be commented upon and requires a repeat biopsy for receptor status
MR1718946,left breast lump p o carcinoma breast.,right breast lump biopsy.,received 3 grey white linear cores measuring 0.7 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a cellular lesion arranged in nests and sheets consisting of atypical cells with round to oval dark nuclei prominent nucleoli and moderate eosinophilic cytoplasm. mitoses: 5 6 10hpf discerned. stroma shows fibrosis and scattered lymphocytes.,left breast lump biopsy:invasive carcinoma nos grade 2.modified bloom richardson score is 7 9.tubule formation 3nuclear pleomorphism 2mitotic activity 2 7 9
MR1718953,left breast lump carcinoma breast.,biopsy from left breast,received 3 grey white linear cores measures 1 1.5cm. entire tissue processed.,section shows cores of breast parenchyma harboring infiltrating lesion arranged n tubules cords . the lesional cells are round to oval having vesicular nuclei prominent nucleoli and moderate cytoplasm. stroma shows desmoplasia. mitosis 6 7 10hpf,left breast lumpinvasive ductal carcinoma grade iimodified bloom richardson score is 6(2+2+2)
MR1718975,right breast lump p o carcinoma breast.,right breast lump biopsy.,received multiple grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by diffuse sheets islands and cords of neoplastic cells with round to oval pleomorphic hyperchromatic nuclei irregular nuclear borders and moderate eosinophilic cytoplasm. also seen group of bizarre looking cells with markedly pleomorphic nuclei. stroma shows desmoplasia and lymphoplasmacytic infiltrates. mitotic figures 10 12 10hpf are discerned.,right breast lump biopsy:invasive carcinoma nst grade 3.modified bloom richardson score is 9 9.tubule formation 3nuclear pleomorphism 3mitotic activity 3 9 9
MR1718978,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received 6 grey white linear cores measures 0.5 to 1.5cm. entire tissue processed.,section shows linear cores of infiltrative lesion arranged in in cords trabecular and in sheets. the cells are pleomorphic with round to oval vesicular nuclei prominent nucleoli and abundant cytoplasm. areas of hyalinisation and fibrosis are seen.,right breast lump biopsy :invasive ductal carcinoma nos grade iimodified bloom richardson score is 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 .
MR1718995,right breast lump malignant.,biopsy from right breast lump.,received 3 grey white linear cores measures 1 1.2cm. entire tissue processed.,section from breast parenchyma shows neoplastic cells arranged in cords singly scattered. the cells are pleomorphic with round to oval hyperchromatic nuclei and moderate cytoplasm. extensive areas of hyalinisation and desmoplasia are noted.,biopsy from right breast lump.invasive carcinoma nuclear grade ii.
MR1719035,carcinoma right breast.,a) wide local excision right breast lump.b)revised superior margin,a) received lumpectomy specimen measures 5x4x1.5cmcut surface shows a grey white ill defined areas measures 3x2.5x2.5cm. distance from margins:superior margin : 0.2cminferior margin : 0.6cmmedial margin : 0.9cmlateral margin : 1.5cmdeep margin : 0.8cmb) received fibrofatty tissue measures 4x3x2cm one surface is inked.,section studied show numerous ducts compressed and dilated lined by epithelial and myoepithelial cells with surrounding hypercellular stroma. few of foci shows increase in number of ducts. no periductal stromal condensation is noted. mitosis 2 3 10hpf.,a) wide local excision right breast lump: cellular fibroadenoma tumor measures 3cm in greatest dimension all resected margins are unremarkable b)revised superior margin is free ot tumor.
MR1719040,right breast lump possibility of carcinoma breast,biopsy from right breast,received 2 linear cores measures 0.7 0.8cm. entire tissue processed.,section shows cores of breast parenchyma harboring infiltrating lesion arranged in tubules and cords. the lesional cells are round to oval having hyperchromatic nuclei and scant cytoplasm. stroma shows desmoplasia with lymphocytic infiltrate. mitosis 4 5 10hpf.,right breast lump:invasive ductal carcinoma grade iimodified bloom richardson score is 6(3+2+1)
MR1719087,right breast lump carcinoma breast.,right breast lump core biopsy.,received multiple grey white linear cores measures 0.6 to 0.8 cm. entire tissue processed.,section shows cores of breast tissue with few foci of tumor cells in diffuse sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1719153,left breast lump possibility of carcinoma breast.,trucut biopsy left breast lump.,received 5 gray white linear cores measures 1 to 1.2 cm. entire tissue processed.,section show linear tissue cores harboring an infiltrate tumor cells show increased nucleo cytoplasm ratio nuclear pleomorphism hyperchromasia occasional prominent nucleoli and variable amount of cytoplasm. the surrounding stroma is fibro collagenous conclusive tissue infiltrated by lymphoplasmacytic inflammatory infiltrate. focal myxoid areas seen. scanty necrosis is noted.,trucut biopsy left breast lump :invasive carcinoma breast grade ii modified bloom richardson score 6 9.tubule formation 2nuclear pleomorphism 2mitotic figures 2 ........... 6 9 ...........
MR1719154,left breast lump possibility of carcinoma breast.,biopsy from left breast lump biopsy.,received 4 gray white linear cores measures 0.8 to 1cm. entire tissue processed.,section show multiple linear cores with an infiltrating tumor arranged in the form of nests and sheets. the tumor cells show moderate nuclear pleomorphism oval hyperchromatic nuclei with occasional nucleoli and moderate amount of eosinophilic cytoplasm. mitotic figures are discerned. focal necrosis is seen.,biopsy from left breast lump :invasive ductal carcinoma grade ii.modified bloom richardson score 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 ........... 7 9 ............
MR1719160,right breast lump possibility carcinoma breast.,biopsy from right breast.,received 3 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section show linear cores harboring an infiltrating lesion arranged in cords and nests . the individual tumor cells exhibit increased nucleocytoplasmic ratio nuclear hyperchromasia pleomorphism and variable amount of eosinophilic cytoplasm. comedo necrosis is seen the stroma shows desmplasia is infiltrated by lymphoplasmacytic infiltrate and shows focal myxoid change,biopsy from right breastinvasive carcinoma breast grade iimodified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1719177,left breast lump possible of carcinoma breast.,biopsy left breast lump.,received four gray white mucoid linear cores measures 0.8 to 1cm. entire tissue processed.,section show fragmented tissue bits harboring an infiltration lesion arrange as clusters of uniform small cells exhibiting nuclear hyperchromasia pleomorphism and eosinophilic cytoplasm in abundant pools of extracellular mucin. the stroma is d fibrocollagenous.,biopsy left breast lump.mucinous carcinoma.(nuclear grade 1)
MR1719187,left breast lesion birads,left breast biopsy.,received multiple grey white linear cores measures0.4 0.5cm. entire tissue processed.,section from the breast parenchyma shows a infiltrating neoplasm arranged in sheets. the neoplastic cells are round to oval with hyperchromatic nuclei scanty cytoplasm lymphoplasmacytic infiltrating seen. mitotic figures 5 6 hpf.,left breast biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 7( 3+2+2).
MR1719189,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received4 grey white linear cores measures 0.8 1cm. entire tissue processed.,sectionfrom left breast lump shows clusters of neoplastic cells . the cells round to oval nucleus moderate amount of eosinophilic cytoplasm. mitotic figures discerned.,biopsy from left breast lump:invasive ductal carcinoma nst grade iimodified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism :2mitotic figures :2
MR1719203,right breast lump carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section show tissue cores harboring in infiltrative lesion arranged in sheets and nests of neoplastic cells exhibiting increased nucleo cytoplasmic ratio nuclear hyperchromasia pleomorphism and prominent nucleoli and variable amount of pale eosinophilic to vacuolated cytoplasm. the stroma is infiltrated by lymphoplasmacytic infiltrate.,biopsy from right breastinvasive carcinoma breast nos grade iiimodified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1719206,bilateral carcinoma breast post op ct.,endometrial lesion endocervical .,received multiple grey white soft tissue bits altogether measures 2.5x1.5x0.5cm. entire tissue processed.,section show fragments of neoplastic tissue arranged in a papillary configuration with fibrovascular core. extensive areas of necrosis are seen. the cells have round to oval hyperchromatic nuclei and moderate cytoplasm.,endometrial lesion. :well to moderately differentiated adenocarcinoma. endometrial origin. endocervical origin. suggest ihc.
MR1719214,right breast carcinoma breast.,biopsy from right breast.,received 3 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,needle core biopsy form right breast shows cells arranged in clusters . the cells show hyperchromatic nucleus conspicious nucleoli and eosinophilic cytoplasm.,biopsy from right beast :invasive carcinoma nst.modified bloom richardson score is 6 9 nuclear grade iitubule formation : 3nuclear pleomorphism : 2mitotic figures :1 6 9
MR1719216,left breast lesion likely malignant,left breast lesion biopsy.,received 5 grey white linear cores measures 0.5 to 1.2 cm. entire tissue processed.,section shows linear of tissue infiltrated by islands cords and trabeculae consistent of atypical cells having round to oval pleomorphic nuclei prominent nucleoli and moderate eosinophilic to pale granular cytoplasm. brisk mitosis discerned. stroma shows fibrosis and hyalinisation. areas of necrosis noted.,left breast lesion biopsy:invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+2+3).
MR1719218,left breast lump carcinoma breast.,left breast lump biopsy.,received 6 grey white linear cores measures 1 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma showing few proliferative glands with cystic change and few areas showing apocrine change. focal areas shows mild epithelial hyperplasia with adenosis. stroma shows extensive hyalinisation and focal myxoid areas.,left breast lump biopsy:features are suggestive of benign proliferative breast disease.kindly correlate with clinical and radiological findings.
MR1719230,right breast lump carcinoma breast.,biopsy from right breast.,received multiple grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section show linear cores of fibrocollagenous tissue with an infiltrating lesion arranged in nests and sheets. the cells have moderately pleomorphic round to oval hyperchromatic nuclei and moderate amount of cytoplasm. intratumoral lymphoplasmacytic infiltrate noted. stroma show desmoplasia.,biopsy from right breast:invasive ductal carcinoma grade 3modified bloom richardson score is 8(3+3+2).
MR1719237,right breast lump carcinoma breast.,biopsy from right breast lump,received 4 grey white linear cores measures 0.5 1.2cm. entire tissue processed.,sectionfrom right breast lump shows cells arranged in nests and cords. the cells are mildly pleomorphic show hyperchromatic nucleus and scanty cytoplasm.,biopsy from right breast lump:invasive carcinoma nst grade iimodified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism :2mitotic figures :1
MR1719255,left breast lump carcinoma breast,left breast lump. core biopsy.,received 3 grey white to grey brown liner cores measures 1.2 to 1.3cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump. core biopsy:invasive ductal carcinoma grade 2modified bloom richardson score is 6(3+2+1)..
MR1719280,right breast lump carcinoma breast.,right breast core biopsy.,received 5 grey white linear cores measures 1 to 1.2 cm. entire tissue processed.,section section tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1719284,right breast lump possibility of carcinoma breast.,biopsy from right breast,received multiple grey white linear cores measures 0.5 to 1cmcm. entire tissue processed.,section shows cores of breast parenchyma with an infiltrating lesion arranged in nests tubules and cords. cells have oval hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. stromal desmoplasia noted. lymphoplasmacytic infiltration noted.,biopsy from right breast:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphisml:2mitotic figures :2 7 9
MR1719285,left breast lump carcinoma breast,biopsy from left breast lump.,received multiple grey white linear cores measures 1 1.2cm.entire tissue processed.,section shows breast parenchyma with an infiltrating lesion arranged in sheets nests and cords . cells have moderately pleomorphic hyperchromatic nuclei and moderate cytoplasm. frequent mitoses noted. angioinvasion is seen. areas of necrosis noted.,biopsy from left breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1719287,right breast possibility of carcinoma breast.,biopsy from right breast.,received 3 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows cores of breast parenchyma with an infiltrating lesion arranged in sheets nests and cords. cells have hyperchromatic nuclei and moderate cytoplasm.frequent mitosis noted .,biopsy from right breast:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures :2 7 9
MR1719345,right nipple discharge.,cone excision of right ductal system,received fibrofatty tissue altogether measures 6x4.5x2.5cmcut surface grey white soft tissue to firm area measuring 1.5x1.5x1.3cm3 small cystic structures identified measuring 0.1 0.3cm diameter.distance from the nearest margin is 1.3cm.,multiple sections studied from the breast parenchyma show ducts filled with slender branching fibrovascular cores covered by uniform appearing columnar epithelial cells. also there is solid arrangement of cells with round to oval nuclei fine nuclear chromatin occasional conspicuous nucleoli and scant to moderate pale eosinophilic cytoplasm. .no evidence of lymphovascular invasion . the intervening stroma has fibrocollagenous connective tissue.impressioncone excision of right ductal system:papillary ductal carcinoma in situ with small focus suspicious of invasionimmunohistochemistry done on the suspicious focus :immunohistochemistry:*calponin and *p63 highlights myoepithelial cells*keratin 5 highlights basal cells*er 75 positive in the dcis component *pr 90 positive in the dcis component,no invasion seen papillary dcis in a background of papillary hyperplasia
MR1719359,left axillary node deposits,biopsy from left axillary lymph node,received multiple fragmented linear cores measures 0.3 0.8cm. entire tissue processed.,section shows cores of tissue harboring an invasive neoplasm in nested pattern with cells having moderate cytoplasm pleomorphic lymphocytic nuclei and prominent nucleoli. the tumor appears to occupying the surrounded spaces. interspersed are lymphoid follicles.,biopsy from left axillary lymph node:metastatic carcinoma in a known case of carcinoma breast.
MR1719366,left breast lump 9 luq) possibility of carcinoma breast.,left breast lump biopsy.,received 4 grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue processed,section shows multiple cores of breast tissue harboring invasive neoplasm in sheets cords and nests . the cells show increased n c ratio moderate eosinophilic to clear cytoplasm hyperchromatic nuclei with moderate pleomorphism and prominence nucleoli. there is focal peritumoral lymphocytic infiltration. tumor appears to infiltrating to the fat.,left breast lump biopsy:invasive carcinoma nst grade 2modified bloom richards son score 6(3+2+1)
MR1719378,left breast lump carcinoma breast.,left breast lump biopsy.,received 5 gray white to gray brown linear cores measures 1 1.3cm. entire tissue processed.,section shows cores of breast tissue harboring invasive neoplasm in sheets nests and glands showing moderate eosinophilic cytoplasm. pleomorphic hyperchromatic nuclei and prominent nucleoli. there is increased mitosis stroma is desmoplastic.,biopsy from left breast lump :invasive ductal carcinoma grade 3. modified bloom richardson score 8(2+3+3).
MR1719444,right breast lump carcinoma breast.,biopsy from right breast.,received 4 grey white to grey brown linear cores measures 1.2 to 1.4cm. entire tissue processed.,section shows multiple linear cores with an infiltrating neoplasm arranged in nests cords and focally in tubules the neoplastic cells show moderate nuclear pleomorphism round to oval hyperchromatic nuclei and scant to moderate cytoplasm few cells show cytoplasmic vacuolation of epithelial cells with central necrosis surrounding stroma shows hyalinisation.,right breast lump biopsy:invasive ductal carcinoma grade iimodified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphic : 2mitotic figures : 2 6 9
MR1719486,right breast lump carcinoma breast.,right breast lump biopsy.,received 4 grey white to grey brown linear cores measures 0.5 to 0.8cm. entire tissue processed,section shows multiple cores at breast tissue harboring an invasive neoplasm composed of atypical cell in nests and tubules. the cells have increased n c ratio moderate eosinophilic vacuolated cytoplasm hyperchromatic nuclei with moderate pleomorphism. stroma is desmoplasia.,right breast lump core biopsy :invasive ductal carcinoma grade 3. modified bloom richardson score is 8(2+3+3).
MR1719500,left breast lump carcinoma breast,left breast lump biopsy.,received 5 grey white to grey brown linear cores measures 0.5 to 1 cm. entire tissue processed.,section shows multiple cores of breast tissue harboring an invasive neoplasm in tubule and nests. the cells show moderate eosinophilic to clear cytoplasm moderate nuclear pleomorphism with hyperchromatism stroma is desmoplastic and hyalinised.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(2+2+2).
MR1719507,right breast lump carcinoma breast.,right breast lump.,received 7 grey white linear cores measures 1 to 1.2 cm. entire tissue processed.,section sows linear core of fibrocollagenous tissue infiltrated by irregular islands cores and trabecular of pleomorphic cells having oval moderate eosinophilic cytoplasm. intersperse lymphoplasmacytic infiltrates are noted. stroma shows extensive desmoplasia. mitosis 3 10hpf.,right breast lump core biopsy :invasive ductal invasion grade 2. modified bloom richardson 6(3+2+1).
MR1719512,right breast lump likely malignancy.,right breast lump biopsy.,received multiple grey white to grey yellow linear cores measures 0.2 to 0.5 cm. entire tissue processed,section shows multiple core of breast tissue harboring predominantly in linear cores or scattered tubules. individual tumor cells show moderate nuclear pleomorphism hyperchromatism and moderate eosinophilic cytoplasm.,right breast lump core biopsy :invasive carcinoma (nst) grade 2 modified bloom richardson score 6(3+2+1).
MR1719531,left breast lump carcinoma breast.,biopsy from left breast.,received 5 grey white to grey brown linear cores measures 1 1.2cm. entire tissue processed.,section shows multiple linear cores with an infiltrating tumor arranged in nests and cords. the tumor cells show moderate nuclear pleomorphism with oval nuclei coarse chromatin and scant to moderate cytoplasm. many mitotic figures are seen. surrounding stroma shows hyalinisation and chronic inflammation.,left breast lump biopsy:invasive ductal carcinoma nuclear grade 3modified bloom richardson score is 7 9tuble formation : 3nuclear pleomorphic : 2mitotic figures : 2 6 9
MR1719533,k c o ca breast post mrmright axillary mass possibility of recurrence mets.,right axillary mass.,received 4 gray white linear cores measures 0.8 to 1.2cm. entire tissue processed.,section shows multiple linear cores with an infiltrating neoplasm arranged in nests and cords. the tumor cells show moderate pleomorphism with round to oval nuclei fine chromatin small nucleoli and moderate amount of eosinophilic cytoplasm. focal necrosis is seen surrounding stroma shows desmoplasia many mitotic figures are discerned.,right axillary mass.features are suggestive of invasive ductal carcinoma recurrence in known case of carcinoma breast.
MR1719544,left breast lump carcinoma breast.,biopsy from left breast.,received multiple fragmented linear cores measures 0.2 to 0.6cm. entire tissue processed.,section shows multiple linear cores with an infiltrating neoplasm arranged in sheets. the neoplastic cells show moderate to marked nuclear pleomorphism with round to oval nuclei and occasional small nucleoli. many mitotic figures are seen. surrounding breast shows focal hyalinisation and lymphoplasmacytic inflammation focal necrosis.,left breast lump biopsy:invasive carcinoma nos nuclear grade 3
MR1719564,known case of carcinoma left breast.,liver lesion biopsy.,received 5 grey white linear cores measures 0.6 to 0.7 cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in tubular pattern nests. individual cells have hyperchromatic nuclei moderate amount of cytoplasm.,liver lesion biopsy:suggestive of metastatic carcinoma in a known case of carcinoma breast.
MR1719575,left breast lump carcinoma.,left breast lump.,received 3 gray white linear cores measures 1 1.2cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm composed of sheets glands and nests of neoplasm composed of sheets glands and nests of pleomorphic cells with moderate eosinophilic cytoplasm. pleomorphic hyperchromatic nuclei and prominent nucleoli there is increased mitosis. areas of comedo necrosis noted.,left breast biopsy core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(2+2+2).
MR1719614,right breast lump possibility of carcinoma breast,biopsy from right breast.,received 5 grey white linear cores measures 0.8x1cm. entire tissue processed.,linear cores of breast tissue with scant volume of atypical cells floating in lakes of mucin,biopsy from right breast:suggestive of mucinous neoplasm favour mucinous carcinoma grade 1modified bloom richardson score is 5 9tubule formation : 3nuclear pleomorphism : 1mitotic figures : 1 5 9 note: tumor volume is scant for further workup.
MR1719622,right breast lump carcinoma breast.,biopsy from right breast lump,received 4 gray white linear cores measures 0.8 to 1.2cm. entire tissue processed.,section shows multiple linear areas with infiltrating tumor arranged in nests sheets and cords. the tumor cells show moderate nuclear pleomorphism central nuclei and scant to moderate cytoplasm. many mitotic figures are discerned. focal necrosis is seen.,biopsy from right breast lump :invasive ductal carcinoma grade iii.modified bloom richardson score 8 10.tubule formation 3nuclear pleomorphism 2mitotic figures 3 ......... 8 10 .........areas and necrosis seen.
MR1719658,left breast lump possibility of carcinoma breast,biopsy from left breast,received 5 grey white linear cores measures 0.7 1 cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. large areas of sclerosis are seen.,biopsy from left breast :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1800002,case of left breast carcinoma,a) left sentinel lymph ndoeb) left intramammary nodec) left mastectomy,a) received fibrofatty tissue altogether measures 3x2x1cm isolated 9 lymph nodescut surface shows fatty infiltrationb) received lymph nodes measures 0.5x0.3x0.4cm along with fibrofatty tissue.c) received in : formalin procedure : mastectomy laterality : lefttotal dimensions : medial to lateral :19.5cm superficial to deep :3cm superior to inferior : 16cmskin ellipse :12.5 x 9.5 shows scar measures 2.5cmnipple : normal tumor : multiple tumor size : no lump seen a grey white to grey yellow area measures 3x2x2cm. seen in retroareolar location of tumor :retroareolar regiondeep margin : 3cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail : absent,section from the breast parenchyma shows multiple dilated ducts of varying size lined by luminal and adlumenal cells with ductal carcinoma in situ components seen. adjacent stroma shows inflammatory infiltrate composed of lymphoplasmacytic epitheloid cells foreign body giant cell reaction most cells eosinophils.,a) left sentinel lymph node:10 lymph nodes isolated : none shows tumor metastasis(0 10)b) left intramammary node:1 lymph node identified : shows no metastatic tumor (0 1).c) left mastectomy:tumor bed:shows chronic inflammatory infiltrates composed of lymphoplasmacytic multinucleated giant cellsno residual tumor seen.left mastectomy no residual ductal carcinoma in situ not identifiedlymphovascular invasion not seenperineural invasion not seenposterior resection margin is free of tumornipple and areola is unremarkable lymph nodes sentinel lymph nodes 10 nodes : no depsoit of tumor intramammary lymph node one node:no deposit of tumorpathological state: ypt0n0summary:left mastectomy no residual tumor.lymph nodes sentinel lymph nodes 10 nodes : no depsoit of tumor intramammary lymph node one node:no deposit of tumor
MR1800010,left breast lesion likely malignant,biopsy from left breast lesion,received 4 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue infiltrated by a lesion arranged in tubules and cords. tumor cells have irregular hyperchromatic nucleus moderate cytoplasm. surrounding stroma shows desmoplasia . mitosis descerned,biopsy from left breast lesion:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic activity : 2 6 9
MR1800079,left breast solid cystic lesion.,biopsy from left breast.,received 6 grey white to grey brown linear cores measures 0.3x0.5cm. entire tissue processed.,section shows tiny fragments of breast parenchyma infiltrated by atypical cells arranged in sheets and cords . these cells have moderately pleomorphic nucleus few with prominent nucleoli and moderate cytoplasm.,biopsy from left breast.features favor papillary neoplasm possibility of papillary carcinoma consideredkindly correlate with clinical and imangeological findings.
MR1800128,lump right breast. papillary neoplasm.,biopsy from lump right breast.,received single nodular grey white mass with fibrofatty tissue measures 6x5.5x4cmmass measures 4x3x2cm cut surface well encapsulated grey white areas tumor is 0.2cm away from the ink surface fibrofatty show a grey white lymph node deposit measures 0.9x0.8x0.7cm.,section from the breast show encapsulated papillary lesion with closely packed papillary lined by ductal cells with moderate cytoplasm elongated oval nuclei with granular chromatin. there is panty of myoepithelial cells. focal areas show few clumps of cells present in stroma microinvasion.,biopsy from lump right breast:papillary neoplasm ( capsulated papillary carcinoma). microinvasionsuggest ihc for further confirmation.
MR1800156,left breast lump possibility of carcinoma breast.,left breast lump core biopsy.,received 3 grey white linear cores measures 0.8 to 0.9 cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1800190,right breast lesion likely malignant.,biopsy right breast,received 5 grey white linear cores measures 0.5 to 0.6cm. entire tissue processed.,section shows cores of breast tissue with extensive dcas solid cobrifrom and comedo type few foci show invasive carcinoma in nested and sheet like pattern with moderate nuclear pleomorphism and desmoplastic stroma. scattered peritumeral lympho plasmacell aggregates noted. lvi present.,biopsy right breast invasive carcinoma nstmodified bloom richardson score is 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 ......... 6 9 .........with extensive dcis (high grade)lymphovascular invasion present.
MR1800211,lump left breast,left breast lumpectomy.,received lumpectomy specimen measures 8x7x4cm .cut surface shows ill defined grey white area noted measures 3x3x2cm.distance from margin:superior margin : 2.5cmmedial margin : 0.5minferior margin : 0.2cmlateral margin :0.1cmdeep margin :0.9cm.,section from breast shows extensive areas of ductal carcinoma in situ ( comedonecrosis and cribriform pattern) with a focus of invasive carcinoma .the tumor cells are arranged in an acinar pattern having pleomorphic vesicular nucleus prominent nucleoli and moderate cytoplasm. dense mononuclear infiltrate is noted.,left breast lumpectomy:extensive ductal carcinoma in situ with foci of invasion.ductal carcinoma in situ component measures 2.6cminvasive component measures 0.4cm in its greatest dimension.lymphovascular invasion is not identifiedperineural invasion is not identified lateral margin is 0.1cm away from the focus of dcis.all other margins of resection are free of tumor.deep margin is free of tumor.
MR1800222,left breast lump possibility of carcinoma breast.,biopsy form left breast growth biopsy.,received 3 grey white linear cores measures 0.6 to 0.7cm. entire tissue processed.,section shows comes of fibro adipose tissue harboring an invasive neoplasm in sheets and nests with abundant to moderate eosinophilic cytoplasm pleomorphism nuclei. with hyperchromatism pleomorphism nuclei stroma appears desmoplastic.,biopsy form left breast growth biopsy.invasive carcinoma ductal (nos) grade ii.modified bloom richardson score is 6 9.tubule formation 3nuclear pleomorphism 2mitotic figures 1 .......... 6 9 ..........
MR1800261,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received 6 grey white linear cores measures 0.6 to 0.7cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harbouring a neoplastic lesion arranged in sheets cords and trabeculae. the cells are pleomorphic with moderate cytoplasm round to oval vesicular nuclei prominent nucleoli extensive areas of hyalinisation seen. areas of necrosis noted.,biopsy from left breast.invasive ductal carcinoma grade ii modified bloom richardson score is 6 9.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 ........... 6 9 .............
MR1800281,post lumpectomy carcinoma breast. margins were positive,a) right breastb) axillary lymph node dissection,a) received wide excision specimen with skin ellipse measures 7x2.5x1.5cmskin ellipse measures 7cm. surface shows linear scar.serial sections show an identified grey white area measures 1.5x1x0.6cmdistance from margins:superior margin: 1.5cminferior margin : 1.5cmmedial margin : 5.0cmlateral margin : 2.5cmdeep : reaching upto deep margin.b) received fibrofatty tissue measures 8x6x2cm largest lymph node measures 2x1x1cm. cut surface grey white.,section from tumor bed show inflammatory granulation tissue and foreign body giant cell reaction. no evidence of in situ or invasive carcinoma in the sections examined.,a) right breast post lumpectomy wide excision of tumor bedno residual viable tumor presentno lymphovascular invasion perineural invasion no ductal carcinoma in situthe resected margins are freeb) axillary lymph node:fifteen lymph nodes isolated are free of tumor (0 15).
MR1800284,left breast possibility of carcinoma breast.,left breast biopsy.,received 4 grey white linear cores measures 0.8 to 1 cm. entire tissue processed.,section from the breast parenchyma shows a infiltrating lesion arranged in sheets nests and cystic dilated glands with eosinophilic secretion. the neoplastic cells are round to hyperchromatic nuclei scant to moderate cytoplasm. a intermixed lymphoplasmacytic infiltrates.,left breast biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1800361,right breast lump carcinoma breast.,right breast lesion biopsy..,received 6 grey white linear cores of 0.3 to 0.4cm. entire tissue processed.,section show small fragments of fibrocollagenous tissue with a lesion arranged in papillary pattern .the lesional cells have round hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm. minimal atypia is noted.,right breast lesion biopsy:papillary neoplasmneeds larger tissue for further categorisation.
MR1800379,right breast lump possibility of carcinoma breast.,right breast.,received 4 grey white linear cores measures 0.5 to 1.2cm. entire tissue processed.,section shows cores of breast tissue with ducts showing extensive dcis papillary and comedo type (high grade)adjacent foci show invasive carcinoma with moderate nuclear pleomorphism and present nucleoli. calcification noted in dccs component.,right breast.invasive carcinoma ductal (nos)modified bloom richardson score is 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 .......... 6 9 ..........with extensive dcis comedo and papillary type
MR1800410,left breast lump possibility of carcinoma breast.,,received 3 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows cores of breast tissue are invasive neoplasm in nests and sheets with moderate nuclear atypia and increased mitosis. ductal carcinoma in situ solid type (high grade) present. stroma is desmoplastic..,invasive ductal carcinoma.nos grade ii.modified bloom richardson score is 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 ........ 7 9 ........with ductal carcinoma in situ solid type and lymphovesicular invasion
MR1800421,right breast lump carcinoma breast.,right breast lump.,received 4 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in sheets and nests. the cells show moderate nuclear pleomorphism eosinophilic cytoplasm and increased mitosis. areas of ductal carcinoma in situ comedo type (high grade) present. necrosis seen.,right breast lump biopsy. invasive ductal carcinoma.modified bloom richardson score is 7 9.tubule function 3nuclear pleomorphism 2mitotic figures 2 ......... 7 9 ..........nuclear grade iiwith comedo type ductal carcinoma in situ.
MR1800434,right breast lesion birads carcinoma malignant,right breast lesion biopsy,received 8 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows cores of tissue infiltrating by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lesion biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1800461,left breast lump carcinoma breast.,left breast lump biopsy.,received 4 grey white linear cores measures 0.8 x 0.1 cm. entire tissue processed.,section shows multiple lesion cores with an infiltrating tumor arranged in nests and occasionally in tubules. the tumor cells show mild to moderate nuclear pleomorphic with hyperchromatic nuclei. occasional mitotic figures are seen.,left breast lump biopsy :invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1800475,not provided.,biopsy from left breast.,received 2 grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section shows cores of fibro adipose tissue harboring an invasive neoplasm in sheets and nests composed of cells with moderate nuclear pleomorphism moderate eosinophilic vacuolated cytoplasm and increased mitosis. stroma is desmoplastic and hyalinized.,biopsy from left breast.invasive ductal carcinoma (nos)modified bloom richardson score is 7 9.tubule formation 3nuclear pleomorphism 2mitotic figures 2 ......... 7 9 .........grade ii.
MR1800485,right breast lump birads 3 lesion.,a) right breastb) left breast,a) received 4 grey white linear cores of 0.8 to 0.9cm. entire tissue processed b) received 6 grey white linear cores of 0.7 to 0.8cm. entire tissue processed.,section shows fibrocollagenous tissue with ducts lined by epithelial and myoepithelial cells .ducts show epithelial hyperplasia .the stroma shows fibromyxoid focal areas of hyalinisation. focal adenosis noted. no definite evidence of malignancy in the section studied.b) section shows linear cores of an infiltrative neoplasm arranged in sheets. the tumor cells have pleomorphic round hyperchromatic nucleus and moderate cytoplasm. areas of ductal carcinoma in situ with comedo necrosis is seen. mitosis discerned.,a) right breast:benign proliferative breast disease suggestive of fibroadenomab) left breast:infiltrating ductal carcinoma grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1800488,right breast lump carcinoma breast.,biopsy from right breast lump.,received 3 grey white linear cores measures 0.8 to 1 cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in sheets nests and focal tubular pattern. the cells show moderate nuclear atypia increased mitosis and moderate eosinophilic cytoplasm. areas of necrosis present.,biopsy from right breast :invasive ductal carcinoma (nos)modified bloom richardson score is 8 9.tubule formation 3nuclear pleomorphism 2mitotic figures 3 ........ 8 9 ........grade iii.
MR1800500,left breast lump carcinoma breast.,biopsy of left breast lump.,received 3 grey white linear cores measures 1.5 to 1.8cm. entire tissue processed.,section show cores of breast tissue harboring an invasive neoplasm in nests and cords. few areas show indian file pattern of cells. there is moderate nuclear pleomorphism. stroma is desmoplastic.,invasive carcinoma with lobular features.modified bloom richardson score is 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 ....... 6 9 .......grade ii.
MR1800519,right cervical lymph node.,right cervical lymph node biopsy.,received multiple grey white soft tissue bits measures 1x1x0.5cm. entire tissue processed.,section shows fibrofatty tissue harboring atypical cells in nests and sheets. the lesional cells are having hyperchromatic nuclei scant cytoplasm crush artifacts noted. foamy histiocytes congested blood vessels seen.,right cervical lymph node biopsy :poorly differentiated malignancy possibly metastatic deposit in known and treated case of carcinoma breast.
MR1800545,right breast lump possibility of carcinoma breast,biopsy from right breast lump,received multiple grey white linear cores measures 1.2 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a lesion arranged in sheets cords. the cells are pleomorphic with round to oval hyperchromatic nuclei and moderate cytoplasm. extensive areas of hyalinisation seen. occasional mitotic activity seen.,right breast lump:invasive carcinoma nst grade 2modified bloom richardson score 6 9.tubule formation 3nuclear pleomorphism 2mitotic activity 1
MR1800571,right breast lump likely malignant.,biopsy from right breast.,received 4 grey white linear cores measures 0.8 to1cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in sheets and nests the cells show moderate anuclear pleomorphism with scattered peritumoral inflammation.,biopsy right breast.invasive carcinoma ductal (nos) grade ii.modified bloom richardson score is 7 9.tubule formation 3nuclear pleomorphism 2mitotic figures 2 .......... 7 9 ..........
MR1800615,left breast lesion possibilities of carcinoma breast.,left breast biopsy.,received 10 grey white to grey brown linear cores measures 0.5 to 1cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue harboring an invasive neoplasm arranged in glandular pattern and nests. tumor cells are pleomorphic round to oval with pleomorphic hyperchromatic nucleus and prominent nucleoli. mitotic figures are 8 10 10hpf. stroma is desmoplastic with dense lymphoplasmacytic infiltrate. areas of necrosis and hemorrhage seen and ill defined granuloma formation seen.,left breast lump biopsy :invasive ductal carcinoma grade 2 with associated granulomatous inflammation. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1800620,carcinoma left breast.,a)left breast wide local excision.b)sentinel lymph nodes.,a) received lumpectomy specimen measures 5.5x5x3 cmskin ellipse 2.8x2 cmcut surface shows ill defined 1.2x1x0.9 cmdistance from margin: superior margin 1.6 cminferior margin 1.7 cmmedial margin 2 cmlateral margin 2.1 cmdeep margin 2.4 cmb) sentinel lymph nodes : received 3 nodes largest measures 1.1x0.8x0.6 cm cut surface shows fatty infiltration.,section from breast shows an infiltrating lesion arranged in tubular small nests and cords consisting of neoplastic cells having round to oval pleomorphic vesicular nuclei prominent nucleoli and moderate eosiniphilic cytoplasm. interspersed lymphocytic and plasma cells are noted. ductal carcinoma in situ identified solid and comedonecrosis type. stroma shows extensive desmoplasia and fibrosis.mitotic figures 12 15 10 hpf discerned.,a)left breast wide local excision:invasive ductal carcinoma with ductal carcinoma in situ (dcis) solid and comedonecrosis type grade 2.modified bloom richardson score:7 9.tubular formation 2nuclear pleomorphism 2 mitotic figures 3 7 9 invasive component measures measures 1 cm.all margins of resection(superior inferior medial and lateral) including deep margin are free of tumor.lymphovascular invasion and perineural invasion are not identified.b) sentinel nodes:none of the four lymph nodes shows tumor deposits (0 4).
MR1800636,left breast lump possibility of carcinoma breast,biopsy from left breast.,received 5 grey white to grey brown linear cores measures 0.8 to 1cmcm. entire tissue processed.,sections hows cores of breast parenchyma with infiltrating lesion arranged in sheets nests and cords cells have moderately pleomorphic hyperchromatic and moderate amount of cytoplasm. stroma desmoplasia is noted. frequent mitosis noted.,biopsy from left breast:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9(2+2+2)
MR1800642,right breast lump carcinoma breast,right breast lump biopsy,received 5 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section show linear tissue cores harboring an infiltrative lesion arranged in cords small nests and discretely scattered neoplastic cells. tthe individual cells exhibiting increased n c ratio pleomorphic hyperchromatic nuclei conspicuous nucleoli scanty cytoplasm. the intervening stroma shows is dense fibrocollagenous connective tissue,right breast lump biopsy:invasive carcinoma no special type grade iimodified bloom richardson score is 6 9 ( 3+2+1)
MR1800649,right breast lesion fibroadenoma. left beast lesion carcinoma breast,a) right breast lesion b)left breast lesion,a) received multiple cores measures 0.8x1.2cm entire tissue processed.b) received 3 grey white linear cores measures 0.8 to 1.2cm. entire tissue processed.,a) section shows linear trucut cores of breast parenchyma infiltrated by tubules cords and singly scattered atypical cells with irregular hyperchromatic nuclei and inconspicuous nucleoli. ductal carcinoma in situ noted. stroma shows desmoplasia.b) section shows linear trucut cores of fibrocollagenous tissue infiltrated by few atypical cells having hyperchromatic nuclei and inconspicuous nucleoli with focal mononuclear inflammatory infiltrate. extensive crush artifacts is noted hindering morphological evaluation difficult.,a) right breast lesion:invasive ductal carcinoma no special type. grade iimodified bloom richardson score is 6 9 (3+2+1).b) left breast lesionfeatures are suspicious of malignancyhowever in view of extensive crush artefact a repeat biopsy is strongly suggested for conclusive opinion.
MR1800650,left breast lump possibility of carcinoma breast,left breast lump core biopsy.,received 5 grey white linear cores measures 0.4 to 0.5 cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells are showing moderate to marked pleomorphism with hyperchromatic nuclei and moderate amount of cytoplasm. large areas of necrosis are seen. areas of keratinization are seen.,left breast core biopsy:invasive carcinoma with squamous differentiation grade 3 modified bloom richardson score is 8(3+3+2).
MR1800666,left breast lump carcinoma breast.,biopsy from left breast.,received 4 linear cores measures 1 1.5cm. entire tissue processed.,sections hows cores of breast parenchyma with large areas of necrosis and a lesion arranged in sheets and nests . few nests show central comedo necrosis and lymphoplasmacytic infiltrate cells have moderately pleomorphic hyperchromatic nuclei and moderate cytoplasm. few large bizarre cells noted. frequent mitoses are seen.,biopsy from left breast:suggestive of invasive ductal carcinoma grade 2modified bloom richardson score is 7(3+2+2)
MR1800674,left breast lump carcinoma breast,left breast lump biopsy,received 5 grey white linear cores measures0.8 1.2cm. entire tissue processed.,section show linear tissue cores harboring an infiltrative lesion arranged in sheets nests cords and occasional glandular pattern. the individual tumor cells exhibit increased nucleocytoplasmic ratio nuclear hyperchromasia pleomorphism and variable amount of cytoplasm. the intervening stroma is dense fibrocollagenous.,left breast lump biopsy:invasive carcinoma no special type grade iimodified bloom richardson score is 7 9 ( 3+2+2)
MR1800691,left breast lump carcinoma breast.,biopsy from left breast lump.,received 5 grey white linear cores measures 0.8 to 1.3cm. entire tissue processed.,sections show cores of breast tissue harboring an invasive neoplasm in glands and nests with moderate nuclear pleomorphism and increased mitosis with clear to eosinophilic cytoplasm. stroma is desmoplastic. adjacent ducts show atypical ductal hyperplasia.,left breast lump biopsy invasive ductal carcinoma. (nos)modified bloom richardson score is 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 ...... 6 9 .......
MR1800693,post mrm left breast.,biopsy of right breast lesion.,received 7 grey white linear cores measures 0.2 to 1cm. entire tissue processed.,section show cores of fibro adipose tissue harboring an invasive neoplasm in nests and cords with moderate nuclear pleomorphism and increased mitosis in a desmoplastic stroma.,biopsy from right breast. invasive ductal carcinoma modified bloom richardson score is 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 ...... 6 9 ........grade ii
MR1800734,left breast lump carcinoma breast.,biopsy from left breast.,received 6 grey white linear cores measures 1 1.2cm. entire tissue processed.,sections hows linear cores of tissue harboring a lesion arranged in islands cords and trabecular comprising of neoplastic cells having ovoid pleomorphic dark nuclei with prominent nucleoli and moderate eosinophilic cytoplasm. also seen few large bizarre looking infiltrates are noted. stroma lymphoplasmacytic infiltrates are noted. stroma shows hyalinisation.,left breast lump:invasive ductal carcinoma grade 3modified bloom richardson score is 8 9 (3+3+2).
MR1800744,right breast lump carcinoma breast.,right breast lump core biopsy.,received 4 grey white linear cores measures 0.6 0.8cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1800749,right breast lump carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measures 0.8 1cm. entire tissue processed.,linear cores of breast parenchyma harboring a neoplastic lesion arranged in nests sheets . the cells are pleomorphic with round to oval hyperchromatic nuclei moderate cytoplasm. occasional mitotic activity seen. areas of hyalinisation seen.,biopsy from right breast:invasive ductal carcinoma grade 2modified bloom richardson score is (3+2+2) 7 9.
MR1800777,right breast lump possibility of carcinoma breast.,biopsy from right breast lump,received 6 grey white linear cores measures 0.4 0.6cm. entire tissue processed.,section shows linear cores of fibroglandular tissue with numerous dialted ducts lined by epithelial and myoepithelial cells. minimal atypia is noted. increase stromal component noted.,biopsy from right breast lump:proliferative breast diseasefavor phyllodes tumor benign borderlinenote: for further categorization larger tissue required.
MR1800792,left axillary nodal mass deposit.,a)left axillary nodal massb) left breast lump,a) received 3 grey white linear cores measures 0.8 1cm. entire tissue processed.b) received 5 grey white linear cores measures 0.6 0.8cm. entire tissue processed.,a) section shows linear cores tissue cores harboring a lesion arranged as sheets nests glandular structures the individual neoplastic cells exhibiting increased n c ratio pleomorphic hyperchromatic nuclei scanty amount of eosinophilic cytoplasm. extensive necrosis is seen. intervening stroma is compressed of fibrocollagenous connective tissue.b) section shows 5 linear cores harboring an infiltrative lesion arranged in cords nests focal cribriform pattern and few tubules . the individual tumor cells show increased n c ratio nuclear hyperchromasia pleomorphism inconspicuous nucleoli and scanty cytoplasm. the intervening stroma is composed of fibrocollagenous connective tissue.,a)left axillary nodal mas:metastatic carcinomatous deposits.b) left breast lump:invasive ductal carcinoma breast nos grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1800834,left breast lump possibility of carcinoma breast,left breast lump core biopsy.,received 3 grey white linear cores measures 0.8 to 1 cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1800838,right breast lump carcinoma breast,right breast lump core biopsy.,received 4 linear cores measures0.8 to 1 cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1800840,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received 4 grey white linear cores measures 0.6 to 0.8cm.entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged as cords clusters and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nucleus conspicuous nucleoli and moderate cytoplasm. the intervening stroma is elastotic.,biopsy from left breast:invasive ductal carcinoma.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1800870,left breast lump possibility of carcinoma breast.,left breast lump core biopsy.,received 4 linear cores measures 0.8 to 1cm. entire tissue processed.,section shows tumor cells in sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1800903,known case of carcinoma right breast post mrm.,biopsy from left breast lump.,received 3 grey white to grey yellow linear cores measures 0.2 to 0.7cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an infiltrating lesion composed of neoplastic cells arranged in islands tubules and sheets. the lesional cells have moderate amount of cytoplasm pleomorphic nuclei with prominent nucleoli. mitosis are 4 5 10 hpe. stroma shows inflammatory cells.,biopsy from left breast lump : invasive carcinoma (nst) nuclear grade ii.modified bloom richardson score is 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 .......... 6 9 ..........
MR1800911,right breast lump carcinoma breast.,right breast lump core biopsy.,received 4 grey white brown linear cores measures 0.8 to 1cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1800948,left breast lump possibility of carcinoma breast.,left breast lump biopsy,received 3 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma with numerous ducts showing epithelial proliferation in solid and focal cribriform pattern. the cells show round to oval hyperchromatic nuclei with occasional small nucleoli and eosinophilic cytoplasm. foci of invasion are seen.,left breast lump biopsy:shows extensive ductal carcinoma in situ component of solid and cribriform pattern( intermediate nuclear grade) with foci of invasion.
MR1800967,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received 4 grey white to grey brown linear cores measures 0.8 1cm. entire tissue processed.,sections shows linear cores of fibrofatty tissue infiltrated by neoplastic cells arranged in sheets with areas of hemorrhage and necrosis. the cells have round hyperchromatic nucleus with moderate cytoplasm. background stroma shows desmoplasia .lymphovascular invasion is seen. mitosis discerned,biopsy from right breast lump:suggestive of invasive carcinoma note: tumor volume in the block is not adequate suggest repeat biopsy for further work up .
MR1800987,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white to grey brown linear core measures0.5 to 1.2cm. entire tissue processed.,linear cores of breast tissue showing focal usual ductal hyperplasia.,biopsy from left breast:benign breast tissue no evidence of malignancy in in the cores submitted.
MR1801028,post nact carcinoma of right breast,a) right breast lumpectomy ( post nact)b) right axillary lymph node dissection.,a) received lumpectomy specimen measures 5.5x4.3x3cm cut surface ill defined grey white lesion measures 1x0.8x0.8cmdistance from marginssuperior margin:1.2 cminferior margin : 1.5cmmedial margin : 2cmlateral margin : 1.4cmdeep margin : 1.5cmb) received fibrofatty tissue measures 6x4.5x2cmlargest lymph node measures 2.3x1x1cm cut surface fatty infiltration.,a) sections show breast parenchyma harboring an infiltrative neoplasm arranged in nests cords trabeculae and poorly formed glands lined by neoplastic cells exhibiting increased n c ratio pleomorphic hyperchromatic nuclei prominent nucleoli and scant to moderate of pale eosinophilic cytoplasm. the intervening stroma shows fibrocollagenous connective tissue with lymphoplasmacytic inflammatory infiltrate. focal ductal carcinoma in situ component in noted. no evidence of lymphovascular embolus. perineural invasion is seen. the paraffin section of inferior margin shows presence of tumor. however the frozen section of inked margins is free of tumor.rest margins ( superior medial lateral and deep ) are free of tumor.focal presence of well formed granulomas with epithelioid cells and lymphocytic rimming is noted. no necrosis is observed.b) lymph node:10 lymph nodes identified : one shows evidence of metastatic tumor deposits one lymph node shows presence of non necrotising granuloma with epitheloid and langhans giant cells,a) right breast lumpectomy ( post nact):residual invasive ductal carcinoma nst grade iiimodified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2with non necrotising granulomatous inflammation.tumor measures 1cm in greatest dimension.ductal carcinoma in situ is seen solid pattern measuring 0.3cm greatest dimension.perineural invasion is seen.no evidence of of lymphovascular embolib) right axillary lymph node dissection:1 10 lymph nodes show metastatic tumor deposit one lymph node show non necrotiging granulomatous inflammation.
MR1801030,left breast carcinoma breast,biopsy from left breast,received 4 grey white t linear cores measures1 1.2cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring a neoplastic lesion in sheets cords the cells are pleomorphic with round to oval vesicular nuclei prominent nucleoli and abundant cytoplasm. keryorrhectic debris seen. mitosis noted . areas of hyalinisation noted.,biopsy from left breastinvasive ductal carcinoma grade 2 modified bloom richardson score is 7( 3+3+1)
MR1801078,right breast lump possibility of carcinoma breast.,right breast lump biopsy,received 4 grey white linear cores measures 0.8 1.2cm. entire tissue processed,section from the breast parenchyma shows a infiltrative lesion arranged in nests vague glands and individual scattered cells. the cells are round to oval vesicular nuclei moderate eosinophilic cytoplasm. mitosis 4 5 10hpf lymphoplasmacytic infiltration seen.,right breast lump biopsy:invasive ductal carcinoma grade 2 modified boom richardson score is 7 (3+2+2).
MR1801119,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 0.7 to 1cm. entire tissue processed.,h amp e stained section studied shows linear cores of breast parenchyma harboring an infiltrating lesion composed of neoplastic cells arranged in islands and sheets. the lesional cells have moderate amount of eosinophilic cytoplasm pleomorphic hyperchromatic nuclei. mitosis are 6 7 10 hpf .. many inflammatory cells are seen. stroma shows hyalinization. one focus shows ductal carcinoma in situ.,biopsy from left breast lump :invasive carcinoma (nos) nuclear grade ii.modified bloom richardson score is 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 .......... 6 9 ..........focus of ductal carcinoma in situ with comedonecrosis seen.
MR1801122,left breast lump birads iv lesion.,biopsy from left breast.,received 4 linear cores measures 0.8 0.9m. entire tissue processed.,section studied shows multiple cores of breast parenchyma harboring a lesion arranged in papillae and in sheets . the lesional cells have abundant amount of cytoplasm mild nuclear pleomorphism and oval dark nuclei. areas of hemorrhage noted. inflammatory cells composed of lymphocytes seen. foci of necrosis seen. tumor is infiltrating the stroma. mitosis are noted (6 8 10 hpf),biopsy from left breast lump.invasive carcinoma with papillary features nuclear grade ii.
MR1801131,left breast lesion malignant,biopsy from left breast,received 3 grey whit linear cores measures 0.8 1.2cm.entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an invasive neoplasm arranged in ribbons cords and sheets composed of cells showing marked nuclear pleomorphism round to oval vesicular nuclei with prominent nucleoli and moderate amount of cytoplasm. mitosis are 6 8 10 hpf. stroma shows chronic inflammatory infiltrate.,biopsy from left breast:invasive carcinoma breast (nst) grade iimodified bloom richard son score is 7 9 (3+2+2)
MR1801153,left breast lump possibility of carcinoma breast,biopsy from left breast,received multiple grey white fragmented linear cores measures0.2 0.7cm. entire tissue processed.,section shows multiple fragments of tissue harboring a neoplastic lesion arranged in sheets. the cells are markedly pleomorphic with round to oval vesicular nuclei few showing prominent nucleoli abundant cytoplasm. mitotic figures seen.,biopsy from left breast:invasive carcinoma nuclear grade 3modified bloom richardson score is 8 9 ( 3+3+2)
MR1801156,left breast lump carcinoma breast.,biopsy from left breast.,received 4 grey white linear cores measures 0.7 0.1m. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an infiltrating lesion composed of neoplastic cells arranged in islands and sheets. the lesional cells are pleomorphic with round to oval hyperchromatic nuclei and moderate to abundant amount of eosinophilic cytoplasm. mitotic are 6 8 10 hpf. background shows myxoid material. one focus show features of ductal carcinoma in situ.,biopsy from left breast:invasive carcinoma (nst) nuclear grade iimodified bloom richardson score is 7 9 (3+2+2)focus of ductal carcinoma in situ solid type seen.
MR1801181,right breast lump possibility of carcinoma breast,biopsy from right breast,received 3 grey whit linear cores measures 0.6 1cm.entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an invasive neoplasm an invasive neoplasm arranged in ribbons cords and sheets composed of cells showing moderate nuclear pleomorphism round to oval vesicular nuclei with prominent nucleoli and moderate amount of cytoplasm. . few show vesicular nuclei .mitosis are 6 7 10 hpf. stroma shows hyalinilisation,biopsy from right breast:invasive carcinoma breast (nst) grade iimodified bloom richard son score is7 9 (3+2+2)
MR1801189,left breast lump possibility of carcinoma breast.,left breast lump,received 3 grey white linear cores measures 0.7 to 1cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an invasive neoplasm arranged in islands cords and sheets composed of cells showing moderate nuclear pleomorphism round to oval vesicular nuclei with prominent nucleoli and moderate amount of cytoplasm. . few cells show hyperchromatic nuclei. stroma shows dense desmoplasia and sclerosis. mitosis are 3 4 10 hpf. no necrosis and lymphovascular invasion seen.,left breast lump biopsy:invasive carcinoma breast ( nst) nuclear grade ii.
MR1801199,lump right breast papillary neoplasm right breast.,right breast excision of ductal system.,received fibrofatty tissue measures5x5x3cm .cut surface shows cystic areas( 1 cm) that show papillary excrescences another cyst measures 0.6cm .,section show breast parenchyma harboring a lesion arranged in papilla lined by epithelial and myoepithelial cells. few dilated ducts filled with neoplastic cells in papillary pattern seen lined by outer myoepithelial layer .few ducts show eosinophilic section. foci of suspicious of invasion with surrounding desmoplastic stroma seen. adjacent breast show aggregates of foamy macrophages cholesterol clefts lymphocytes and foreign body giant cells. stroma shows fibrosis.,right breast excision of ductal system:papillary neoplasmsuggestive of papillary ductal carcinoma in situ with suspicious foci of invasion.suggest ihc.
MR1801222,a)right breast carcinoma breast.b)left breast carcinoma breast.,a)biopsy from right breast.b) biopsy from left breast,a)received 3 grey whit linear cores measures 1.2 1.5cm.entire tissue processed.b)received 3 grey white linear cores measures 1.5 2cm. entire tissue processed.,a)section studied shows linear cores of breast parenchyma harboring an invasive neoplasm arranged in islands cords and ribbons composed of cells showing moderate nuclear pleomorphism round to oval vesicular nuclei with prominent nucleoli and moderate amount of cytoplasm. mitosis are 6 7 10 hpf. perineural invasion is seen.b) section studied shows linear cores of breast parenchyma harboring an invasive neoplasm arranged in islands cords sheets composed of cells showing moderate nuclear pleomorphism round to oval vesicular nuclei with prominent nucleoli and moderate cytoplasm. mitosis are 4 5 10 hpf.,a)biopsy from right breast:invasive carcinoma breast (nst) grade iimodified bloom richard son score is 7 9 (3+2+2)b) biopsy from left breast:invasive carcinoma breast (nst) grade iimodified bloom richard son score is 6 9(3+2+1)
MR1801280,a)right breast lump carcinoma breast.b)left breast lump infective malignant,a)right breast lump biopsy.b) left breast lump biopsy,a)received 4 grey white linear cores measures 0.5 to 1cm. entire tissue processed.b) received 4 grey white linear cores measures 0.5 to 0.6cm . entire tissue processed.,a) section studied show breast parenchyma shows an infiltrating lesion arranged in nests and sheets. the cells forming the lesion are round to oval with hyperchromatic nuclei with scant to moderate cytoplasm. abundant lymphoplasmacytic infiltrate seen. crush artifacts are seen.b) section shows scant tissue with few dilated ducts and fibrous tissue stroma.,a)right breast lump biopsy:invasive ductal carcinoma nos grade iib) left breast biopsy :no evidence of malignancy seen in the sections studied.
MR1801312,case of right breast carcinoma. post nact.,right modified radical mastectomy.,received in : formalinprocedure : modified radical mastectomy post nact laterality : righttotal dimensions : medial to lateral :22cm superficial to deep :5 cm superior to inferior :20cmskin ellipse 18x13:cmnipple :normalscar surgical defect :not seentumor : multifiocal 2 lesions seen grey white firm lesion in in upper outer quadrant measures 2x1.4x1.3cm. another firm grey white nodular lesion measures 1x1.8x0.6cm seen 2cm from the first lesion. location of tumor : upper outer quadrantmargins of tumor : ill defineddeep margin : 3cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail : 10x9x3cmtotal number of nodes : 11 nodessize of largest node : 2x1x1cm cut surface fatty infiltrate.,residual viable tumor present.maximum dimension of tumor 2cminvasive ductal carcinoma measures 1.2cm. ductal carcinoma in situ ( cribriform and comedo pattern.) 0.8cm.surrounding the tumor areas of necrosis fibrosis and lymphoplasmacytic infiltrate is present.another tumor nodule is present 2cm away from the first tumor measures 1x0.5cm with invasive ductal carcinoma (0.5cm) and ductal carcinoma in situlymphovascular invasion present perineural invasion not identifiedareas of necrosis seen in surrounding breast along with lymphoplasmacytic infiltrate.,right breast right modified radical mastectomy:residual multifocal invasive ductal carcinomamodified bloom richardson score is 6 9 grade ii.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1largest tumor focus measures 2cm in greatest dimension is located in the upper outer quadrant.ductal carcinoma in situ 0.8cmlymphovascular invasion presentperineural invasion not identifiedposterior resection margin is free of tumor.nipple and areola is unremarkable no paget s disease.lymph nodes 11 lymph nodes.metastasis 811 lymph nodes show metastatic deposit of invasive duct cell carcinoma.perinodal spread present.summary:right breast right modified radical mastectomy.residual viable tumor presenttwo tumor nodules show invasive ductal carcinoma with ductal carcinoma in situ grade ii.nodal metastasis: 8 lymph nodes show metastatic deposits of tumor perinodal spread of tumor is seen.
MR1801338,right breast lump malignant,right breast lump,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,section from the breast parenchyma shows a lesion arranged in nests and sheets. the cells forming the lesion are round to oval with hyperchromatic nuclei and scant to moderate cytoplasm. adjacent breast parenchyma shows lymphoplasmacytic infiltrate. mitosis 3 4 10 hpf.,right breast lump biopsy:invasive ductal carcinoma grade iimodified bloom richardson score is 6 9(3+2+1)
MR1801344,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of fibrocollagenous with an infiltrating lesion arranged in cords islands and sheets . the cells have round to oval markedly pleomorphic hyperchromatic nuclei and abundant amount of eosinophilic cytoplasm. few lymphoplasmacytic infiltrate .mitotic figures discerned.,biopsy from left breast lump:invasive ductal carcinoma grade iiimodified bloom richardson ( 3+3+2)8
MR1801349,left breast lump possibility of carcinoma breast.,left breast lump core biopsy.,received multiple fragmented linear cores measures 0.2 to 0.6cm. entire tissue processed.,section shows tumor cells in diffuse sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. few cells with bizarre nuclei are seen,left breast lump core biopsy:invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+3+2).
MR1801362,left breast lump carcinoma breast.,left breast lump core biopsy.,received 6 grey white linear cores measures0.8 1cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1801400,left beast lump possibility of carcinoma breast.,left breast lump biopsy,received 6 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section studied shows cores of fibrocollagenous tissue harboring a neoplastic lesion arranged in sheets and islands. the cells lesional cells have abundant amount of cytoplasm pleomorphic vesicular to hyperchromatic nuclei showing prominent nucleoli. areas of necrosis seen. stroma shows fibrosis.,left breast lump biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1801449,carcinoma right breast ct2n0m0,a) wide excisionb) right sentinel lymph nodec) right axillary lymph node dissection,a) received wide excision specimen measures 6x4.5x3.5cm skin ellipse measures 2x0.3cmcut surface shows a grey white lesion measures 3x2.5x2cmdistance from marginssuperior margin: 0.8cminferior margin :1cmmedial margin :2cmlateral margin :1.2cmdeep margin :1.5cmb) received fibrofatty tissue measures 2.5x1x1cm isolated 3 lymph nodes largest lymph node measures 1.2x1x1cm cut surface grey white . gritty to cut.c) received multiple fibrofatty tissue altogether measures 5x3.5x2cm largest lymph node measures 1x0.8x0.5cm. cut surface grey white.,wide excision:the section shows clumps groups and sheets of pleomorphic cells with hyperchromatic nucleus with eosinophilic cytoplasm. tubule formation less than 10 (3) mitosis (2) anaplasia (2) modified bloom richardson score is 7 9 grade ii.ductal carcinoma in situ not present.lymphovascular invasion present.perineural invasion presentresected margins :superior margin: free of tumorinferior margin : free of tumormedial margin :free of tumorlateral margin :free of tumordeep margin :free of tumorsentinel lymph node:one node shows metastatic deposit of tumor out of 3 nodesperinodal spread present.right axillary lymph node: 19 nodes . no deposit of tumor,breast wide excision:invasive ductal carcinoma measuring 3x2.5x2cm grade ii.lymphovascular invasion present.perineural invasion present.ductal carcinoma in situ not identified.sentinel lymph node:one node shows metastatic deposit of tumor out of 3 nodes..right axillary lymph node: 19 nodes . no deposit of tumor.pathological stage: pt2n1.
MR1801464,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. pools of extracellular mucin are seen.,right breast lump core biopsy:suggestive of invasive carcinoma with mucinous features grade 2 modified bloom richardson score is 6(3+2+1).
MR1801487,left breast lump possibility of carcinoma breast.,biopsy from left breast .,received 4 grey white linear cores measures1 to 1.2cm. entire tissue processed.,linear cores of parenchyma infiltrated by a neoplasm arranged in clusters and cords . the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm . the intervening stroma is hyalinised.,biopsy from left breast .invasive ductal carcinoma grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1801499,right breast lump biopsy.,right breast lump biopsy :,received 4 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in islands and nests. the lesional cells are pleomorphic with hyperchromatic cytoplasm mitosis are 6 7 10 hpf. stroma shows sclerosis and crush artifacts. extensive foci of ductal carcinoma in situ noted.,right breast lump biopsy.suggestive of invasive carcinoma breast (nst) nuclear grade i modified bloom richardson score is 5 9tubule formation 3nuclear pleomorphism 1mitotic figures 1 ......... 5 9 ........foci of ductal carcinoma in situ solid and cribriform type noted.
MR1801528,left breast lump.,biopsy from left breast lump.,received 4 grey white to mucoidal linear cores measures 0.7 to 1.2cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue showing extensive pools of mucin and scattered acini and clusters of neoplastic cells showing moderate eosinophilic cytoplasm enlarged pleomorphic hyperchromatic nuclei. mitosis are discerned. few show prominent nucleoli.,left breast lesion biopsy :invasive carcinoma with mucinous areas nuclear grade i. modified bloom richardson score is 5 9tubule formation 3nuclear pleomorphism 1mitotic figures 1 ........... 5 9
MR1801533,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in islands and sheets. the lesional cells are moderately pleomorphic enlarged hyperchromatic nuclei and abundant eosinophilic cytoplasm. mitosis are 7 8 10 hpf. crush artifacts are noted. one focus of ductal carcinoma in the situ noted. stroma shows sclerosis.,left breast lump biopsy :invasive carcinoma breast (nst) nuclear grade ii modified bloom richardson score is 6 9tubule formation 3nuclear pleomorphism 2mitosis figures 1 ............ 6 9 ............one focus shows ductal carcinoma in situ solid type.
MR1801543,right breast lump carcinoma breast.,right breast biopsy.,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,section from the breast parenchyma shows a infiltrating neoplasm arranged in sheets and nests. the cells are round to oval hyperchromatic nuclei with scant to moderate cytoplasm adjacent stroma shows inflammatory infiltrates . composed of lymphocytes . brisk mitotic figures,right breast biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1801545,right breast lump malignant,biopsy from right breast,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,section shows linear cores breast parenchyma showing presence of an infiltrative lesion arranged in cords nests occasional tubules and discretely scattered . the individual neoplastic cells show increased nucleo cytoplasmic ratio nuclear hyperchromasia pleomorphic and scanty pale eosinophilic cytoplasm. the intervening dense fibrocollagenous connective tissue is infiltrated by lymphocytes. extensive ductal carcinoma in situ is noted. mitotic figures are discerned.,right breast lump :invasive ductal nos grade iimodified bloom richardson score is 7 9*( 3+2+2)
MR1801546,left breast lump carcinoma breast,biopsy from left breast lump,received multiple grey white linear cores measures 1 to 1.2cm. entire tissue processed,section shows linear cores of fibrocollagenous tissue showing focal areas with islands of atypical cells having round to oval dark nuclei irregular margin prominent nucleoli and moderate amount of eosinophilic cytoplasm. stroma shows extensive desmoplasia and lymphoplasmacytic infiltrate. mitotic figures are rare.,biopsy from left breast lump:invasive carcinoma nst grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1801637,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 linear cores measures 0.5 0.7cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating neoplasm arranged in cords and acini. the tumor cells are highly pleomorphic having round to irregular hyperchromatic nucleus.few cells show prominent nucleoli and moderate cytoplasm.,biopsy from left breast lump:invasive carcinoma with lobular features modified bloom richardson score is 8 9(3+3+2).
MR1801647,right breast lump malignant.,right breast core biopsy.,received 5 grey white to grey brown linear cores measures 0.6 0.7cm. entire tissue processed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1801708,carcinoma left breast,left breast incisional biopsy.,received single soft tissue bits altogether measures 0.6 x 0.5 x 0.4 cm. entire tissue processed.,section shows tumor cells arranged in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate of cytoplasm.,left breast incisional biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1801720,left breast lump birads v lesion.,biopsy from left breast lump.,received 3 grey white to grey brown linear cores measures 1 1.2cm. entire tissue processed.,section shows linear cores of fibrofatty tissue infiltrated by neoplastic cells cells arranged in sheets and nests. the tumor cells have pleomorphic round hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm. mitosis is discerned.,biopsy from left breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9( 3+2+2)
MR1801759,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 0.8 to 0.9cm. entire tissue processed.,section shows cores fibro adipose tissue harboring an invasive neoplasm in nests cords and poorly formed tubular. the cells show moderate nuclear pleomorphism eosinophilic to clear cytoplasm and increased mitosis. stroma is desmoplastic.,biopsy left breast.invasive carcinoma ductal carcinoma (nos) grade ii.modified bloom richardson score is 7 9tubular formation 3nuclear pleomorphism 2mitotic figures 2 ....... 7 9 ........
MR1801767,left breast lump malignant,biopsy from left breast lump,received 5 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section from the breast parenchyma shows infiltrating lesion arranged in nests and scattered individual cells. the cells are round to oval hyperchromatic nuclei with moderate clear to eosinophilic cytoplasm. adjacent stroma shows lymphocytic infiltrates. brisk mitotic figures are seen. crush artifacts are identified.,biopsy from left breast lumpinvasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1801779,right breast lesion malignant.,biopsy from right breast lesion.,received 5 grey white linear cores measures 0.6 x 0.7cm. entire tissue processed.,section shows fragments of fibroadipose tissue harboring an infiltrate neoplasm in sheets and nests composed of atypical cells with well defined cell borders moderate eosinophilic cytoplasm. pleomorphic nuclei with hyperchromatism.there is extensive peritumoral lymphoplasmacytic infiltrate.,biopsy from right breast. invasive ductal carcinoma grade iimodified bloom richardson score is 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 ...... 6 9 .......
MR1801818,left breast lump carcinoma breast.,biopsy from left breast lump,received 7 grey white linear cores measures 0.6 to 0.7cm.entire tissue processed.,section shows breast parenchyma with an infiltrating neoplasm arranged in nests and occasional glands. the cells are round to oval with hyperchromatic nuclei moderate cytoplasm. adjacent stroma shows lymphocytic infiltrate.,left breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1801824,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received 4 cores measures 0.6 0.8cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords ribbons and islands composed of pleomorphic cells with moderate amount of eosinophilic cytoplasm irregular hyperchromatic nuclei and vesicular nuclei with prominent nucleoli. mitosis are 4 5 10 hpf. stroma shows sclerosis..,biopsy from left breast lump:invasive carcinoma no special type grade iimodified bloom richardson score is 6 9 ( 3+2+1).
MR1801840,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received 3 cores measures 0.6 0.7cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords islands and tubules. the lesional cells are moderately pleomorphic with moderate eosinophilic cytoplasm and hyperchromatic nuclei. mitosis are 4 5 10 hpf. stroma shows elastosis and chronic inflammatory infiltrate.,biopsy from left breast lump:invasive carcinoma no special type grade iimodified bloom richardson score is 6 9( 3+2+1).
MR1801895,left breast indeterminate lesion.,biopsy from left breast lesion.,received 4 linear cores measures 0.8 1cm. entire tissue processed.,section shows cores of breast tissue showing ducts with preserved lobular architecture the ducts shows focal epithelial hyperplasia . no evidence of ductal carcinoma in situ or invasive carcinoma in sections studied.,biopsy from left breast lesion:benign breast tissueno evidence of malignancy in the material submitted.
MR1801921,right breast lump carcinoma breast.,biopsy from right breast.,received 5 grey white linear cores measures 0.6 to 0.7cm entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in thick bands and sheets. the cells show moderate nuclear pleomorphism eosinophilic to clear cytoplasm and increased mitosis. stroma is desmoplastic comedo necrosis noted. dcis component present. comedo type focal areas show papillary features.,right breast biopsy :invasive ductal carcinoma with focal papillary features with high grade dcis and comedo necrosis. modified bloom richardson score is 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 ...... 7 9 .......grade ii.
MR1801952,left breast lump carcinoma breast..,left breast lump core biopsy.,received 4 grey white linear cores measures0.3 to 0.5 cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1801983,left axilla lump malignant.,biopsy from left axilla lump.,received 4 grey white linear cores measures 0.8 0.9cm. entire tissue processed.,section shows multiple linear cores with an infiltrating tumor arranged in nests and cords . the cells show round to oval hyperchromatic nuclei with occasional nuclei and scant to moderate eosinophilic cytoplasm. surrounding stroma shows chronic inflammatory infiltrate.,biopsy from left axilla lump:poorly differentiated carcinomakindly exclude primary in breast.
MR1802007,right breast lump carcinoma breast.,biopsy from right breast lump.,received 3 grey white linear cores measures 0.6 to 0.7cm. soft tissue processed.,section shows cores of fibro adipose tissue harboring cell invasive neoplasm in cords and nests the cells show moderate nuclear pleomorphism eosinophilic cytoplasm and increased mitosis. areas of calcification noted. stroma is desmoplastic.,right breast biopsy :invasive ductal carcinoma (nos)modified bloom richardson score is 7 9 grade ii.tubule formation 3nuclear pleomorphism 2mitosis figures 2 .......... 7 9 ..........
MR1802062,left carcinoma breast post op,biopsy from left chest wall lesion,received multiple grey white linear cores measures 0.8 1cm. entire tissue processed.,section show linear cores of collagenous tissue with foci of neoplastic lesion arranged in small islands cores and sheets. the cells have markedly pleomorphic round to oval hyperchromatic nuclei and moderate amount of cytoplasm. mitotic figures discerned.,biopsy from left chest wall lesion:suggestive of recurrence in a known case of carcinoma breast.
MR1802081,left breast lesion. intermediate metastatic.,left breast lesion biopsy.,received 5 linear cores measures 0.4 0.6cm. entire tissue processed.,section shows linear tissue cores harboring a lesion arranged in cored of neoplastic cells exhibiting increased n c ratio pleomorphic hyperchromatic nucleus with variable amount of pale eosinophilic cytoplasm. the intervening stroma is desmoplastic . occasional lymphoid aggregate is noted.,left breast lesion biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1802096,left breast lump likely malignant,biopsy from left breast lump,received multiple grey white linear cores measures0.8 1cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged in nests cords and sheets. the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. few nests of cells have abundant amount of clear cytoplasm. stroma is desmoplastic. mitotic figures discerned,biopsy from left breast lesion:invasive carcinoma nst grade iimodified bloom richardson score is 7(3+2+2).
MR1802118,carcinoma breast post op,biopsy from right adrenal lesion.,received multiple grey white linear cores measures 0.6 0.8cm. entire tissue processed.,section show linear cores tissue harboring a neoplastic lesion arranged in nests and sheets . the neoplastic cells have marked pleomorphic hyperchromatic nuclei and abundant amount of eosinophilic to vacuolated cytoplasm. bizarre tumor giant cells noted. stroma show sclerosis mitotic figures discerned. vascular emboli present,biopsy from right adrenal lesion:poorly differentiated carcinoma primary. secondarysuggest ihc..
MR1802168,left breast post lumpectomy status,a) left breast post lumpectomy status right lumpectomyb) left modified radical mastectomy.,a) received fibrofatty tissue measures 3.8x2x0.5cmcut surface tiny cystic grey white lesion measures 0.8x0.6x0.4cm distance from closest margin measure 0.3cm.b)received in : formalin procedure :modified radical mastectomy laterality : left total dimensions : medial to lateral :30cm superficial to deep :3 cm superior to inferior :22cmskin ellipse :16x7.5cm. linear sutured wound located in the central quadrant nipple :normalscar surgical defect :not seentumor : no gross tumor identifiedtumor size : defect with grey white areas measures 4.5x3x2.5cm location of tumor : central quadrant margins of tumor : ill defined deep margin : 2cm from the defect muscle : absentadjacent breast : fibrofatty tissue axillary tail : 7x4.5x3cmsize of largest node : 1.5x1x0.5cm cut surface grey brown fat infiltration,a)section shows and encapsulated papillary lesion composed of complex papillae lined by cells with mild atypia . adjacent areas show papillary dcis and intra ductal papilloma. no evidence of invasion noted.b) sections from fibrotic areas show adenosis usual ductal hyperplasia papillary hyperplasia apocrine change and lymphoplasmacytic infiltrate.,a) right breast lumpectomy:intracystic papillary carcinoma(encapsulated papillary carcinoma) associated with papillary ductal carcinoma in situ and intra ductal papilloma the tumor measures 0.8cm in greatest dimension.ductal carcinoma in situ papillary type present.circumferential margins are free of tumor.no lymphovascular invasion or perineural invasion identified. b) left post lumpectomy status left modified radical mastectomy:no residual tumor present.ductal carcinoma in situ not identified.lymphovascular invasion not identified.perineural invasion not identified.deep margin is free of tumornipple and areola is unremarkable.lymph nodes 9 lymph nodes examined no metastasis (0 9).summary:a) right lumpectomy :intracystic papillary carcinoma(encapsulated papillary carcinoma) associated with papillary ductal carcinoma in situ and intra ductal papilloma. resected margins are free of tumor.b) left modified radical mastectomy : no residual tumor present. no lymphnodal metastasis (0 9). deep margin is free of tumor
MR1802180,left breast lesion birads v.,left breast lesion core biopsy.,received 5 grey white to grey brown linear core 0.7 0.8cm. entire tissue processed.,section shows extensive ductal carcinoma in situ component with few foci of invasion.,left breast lesion core biopsy :shows ductal carcinoma in situ of solid pattern with intermediate nuclear grade.foci of invasion are also seen.
MR1802205,know case of carcinoma right breast post op ct rt.now liver lesion metastasis.,liver core biopsy.,received 4 grey white to grey brown linear cores measures0.6 to 0.7cm. entire tissue processed.,section shows cores of liver tissue infiltrated by tumor cells in nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,liver core biopsy( know case of carcinoma right breast post op ct rt) :positive for malignancy.suggestive of metastatic carcinoma in know and treated case of carcinoma right breast.kindly correlate with clinical and radiological findings.
MR1802282,left breast lump birads v.,biopsy from left breast .,received 4 grey white linear cores measures 0.6 to 0.7cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords trabecular. the cells are pleomorphic with ovoid hyperchromatic nuclei and scant cytoplasm. areas of hyalinisation seen.,left breast lump biopsy :invasive ductal carcinoma grade i.modified bloom richardson score is 5 9tubule formation 2nuclear pleomorphism 2mitotic figures 1 ...... 5 9 ........
MR1802320,right breast lump carcinoma breast.,right breast core biopsy.,received 5 grey white linear cores measures 0.7 0.9cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1802354,right breast lump malignant.,right breast lesion biopsy.,received 6 linear cores grey white bits measures 0.5cm. entire tissue processed.,section shows core of tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. few cells with bizarre nuclei are seen.,right breast lesion biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 7(3+2+2).
MR1802366,right breast lump carcinoma breast.,right breast lump biopsy.,received 6 grey white linear cores measures 0.6 0.8cm. entire tissue processed.,multiple section show studied show linear cores harboring an infiltrative tumor arranged in nests cords and trabecular of neoplasm cells exhibiting increased n c ratio vesicular hyperchromasia pleomorphism and scanty cytoplasm. the intervening stroma is desmoplastic and shows dense lymphoplasmacytic infiltrative.,right breast lump biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6( 3+2+1).
MR1802391,left lumpectomy left breast lump with uptake on pet recurrence,left breast core biopsy.,received 4 grey white linear cores measures 0.8 0.9cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nucleus and moderate amount of cytoplasm.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1802396,left breast lump carcinoma breast.,biopsy from left breast lump,received 4 grey white to grey brown linear cores measures 0.6 1.8cm. entire tissue processed.,section from needle core biopsy from left breast shows cells arranged in clusters and severe tubular pattern. the cells are pleomorphic show round vesicular nucleus conspicuous nucleoli and eosinophilic cytoplasm. areas of infarction seen.,biopsy from left breast lump:invasive carcinoma nos grade 3modified bloom richardson score is 8 9tubule formation : 2nuclear pleomorphism : 3mitotic figures : 3 8 9
MR1802402,right breast lump carcinoma breast.,biopsy from right breast lump,received 5 grey white to grey yellow linear cores measures0.5 1.2cm. entire tissue processed.,core biopsy section from needle core biopsy from right breast shows cells arranged in clusters and glandular pattern. the cells moderate pleomorphism with cells showing vesicular nucleus small nucleoli and eosinophilic to clear cytoplasm,biopsy from right breast lump:invasive carcinoma nst grade 2modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1802412,left breast lump birads 4,biopsy from left breast lump.,received 4 grey white to grey yellow linear cores measures 1 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters and cords. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is elastotic.,biopsy from left breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1802416,left breast lump carcinoma breast.,biopsy from left breast lump,received 3 linear cores measures 1.0 1.2cm. entire tissue processed.,section from the left breast shows sheets and clusters of neoplastic cells with fibrous tissue . the cells show moderate pleomorphism round nucleus and eosinophilic cytoplasm.,biopsy from left breast lump:invasive carcinoma nst grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1802542,carcinoma left breast.,a)left breast lumpectomy.b)sentinel lymph node.,a) received a lumpectomy specimen measures 4x5.5x1.5cmno skin ellipseon cut section tumor measures 1x1x0.8cm greyish whitedistance from margins:superior margin :0.6cminferior margin :0.7cmmedial margin :1cmlateral margin :1.5cminked deep margin :0.3cmb) received fibrofatty tissue measures 4x3x1cm. 3 lymph nodes isolatedlargest lymph nodes measures 2x1x0.5cm.,section from the lesion shows invasive neoplasm in sheets nests and cords . the cells show moderate pleomorphism and increased mitosis.,a)left breast lumpectomy:invasive carcinoma ductal nos grade iimodified bloom richardson score is 2+2+3 7 9tumor measures 1.1cm in greatest dimension with invasive carcinoma measuring 0.8cmductal carcinoma in situ solid type intermediate nuclear grade present measuring 0.3cmlymphovascular invasion is indeterminate perineural invasion is not identified.lateral margin shows ductal carcinoma in situ however the inked margin is free from tumorall other margins are free of tumor.b)sentinel lymph node:4 lymph nodes isolated are free of tumor (0 4)
MR1802557,right breast lump carcinoma breast.,right breast lump biopsy.,received 5 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords nests and in sheets. the cells have oval pleomorphic hyperchromatic nuclei with moderate cytoplasm. intervening stroma shows lymphocytic infiltrate. mitosis seen. areas of fibrosis seen.,right breast lump biopsy :invasive carcinoma nst grade ii.modified bloom richardson score is 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 ........ 6 9 ...........
MR1802570,left breast lump carcinoma breast..,biopsy from left breast lump.,received 5 grey white to grey brown linear cores measures 1.0 1.2cm. entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged as cords tubules and clusters. the neoplastic cells have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is elastotic.,biopsy from left breast lump:invasive ductal carcinoma grade 2 modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1802601,carcinoma right breast post chemo,right modified radical mastectomy post nact,received in : formalin procedure : right modified radical mastectomy post nact laterality : righttotal dimensions : medial to lateral :16cm superficial to deep : 5cm superior to inferior : 12cmskin ellipse :11.5x7cmnipple :puckering present scar surgical defect : not seentumor :single tumor size :3x2.5x1.7cm location of tumor : central quadrantmargins of tumor : iil defined deep margin : 1.5cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail :12x8x1cm,section studied shows breast parenchyma harboring an infiltrating lesion arranged in nests and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma is desmoplastic with areas of hemorrhage and necrosis.,right modified radical mastectomy post nact:histological type:residual invasive ductal carcinoma.grade :2tumor component maximum dimension 3cm.invasive component measures 3cm.modified bloom richardson score is 7 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2ductal carcinoma in situ is not seen.lymphovascular invasion is seen.perineural invasion is present.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes 16 lymph nodes metastasis 6(6 16).perinodal spread is presentpathological stage ypt2n2summary:residual invasive ductal carcinoma right breasttumor grade 2lymph nodes status 6 16 perinodal spread is seen.
MR1802625,right breast lump possibility of carcinoma breast,biopsy from right breast.,received 4 linear cores measures 0.8cm. entire tissue processed.,section shows linear tissue cores harboring an infiltrative lesion arranged in cords and nests of neoplastic epithelial cells exhibiting increased n c ratio nuclear hyperchromasia pleomorphism occasional prominent nucleolus and pale eosinophilic cytoplasm. the intervening stroma shows presence of fibrocollagenous connective tissue.,biopsy from right breast:invasive ductal carcinoma grade 2. modified bloom richardson score is 6( 3+2+1)
MR1802656,left breast lump carcinoma breast.,left breast lump biopsy.,received 4 linear cores measures measures 0.4 0.6cm. entire tissue processed.,section shows linear cores of fibroadipose tissue harboring an infiltrative lesion arranged in cores and trabecular . the individual neoplastic cells show increased n c ratio nuclear hyperchromasia and pleomorphism moderate amount of pale eosinophilic cytoplasm.the intervening stroma shows desmoplasia and in infiltrated by lymphoplasmacytic infiltrate.,left breast lump biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1)
MR1802661,right breast lump possibility of carcinoma breast.,biopsy from right breast lump,received 4 linear cores measures0.6 0.7cm.entire tissue processed.,section shows multiple fragments of breast parenchyma shows a lesion with increased cellularity. the cells are spindle cells int the background of myxomatous stroma . also seen ducts lined by luminal and abluminal cells.,biopsy from right breast lump:fibroepithelial lesion possibility of phyllodes considered.needs larger tissue for grading and confirmation.
MR1802672,right breast lump possibility of carcinoma breast.,right breast lump biopsy.,received 4 linear cores measures 0.8 1cm. entire tissue processed.,section shows linear tissue cores infiltrated by cords of neoplastic cells exhibiting increased nucleo cytoplasmic ratio hyperchromatic pleomorphic nuclei with occasional prominent nucleoli and scanty eosinophilic cytoplasm. the intervening stroma shows desmoplasia.,right breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1802693,right breast lump possibility of carcinoma breast.,right breast core biopsy.,received multiple grey white linear cores measures 0.6 to 0.7cm. entire tissue processed.,section shows linear cores breast parenchyma with focal aggregates of glands lined by epithelial cells with bland nuclear features . stroma shows dense sclerosis.,right breast core biopsy:benign ductal elements representativeplease repeat if clinically indicated.
MR1802707,prostatomegaly carcinoma breast.,trucut biopsy prostate,received 7 linear cores measures 0.8 1cm. entire tissue processed.,section shows linear cores of prostatic tissue exhibiting acini lined by columnar epithelium interspersed in fibromuscular stroma. no evidence of malignancy.,trucut biopsy prostate :shows benign prostatic tissue.no evidence of malignancy is seen.
MR1802719,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received 4 grey white linear cores measures 0.8 1cm. entire tissue processed.,section shows cores tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1802742,carcinoma left breast ct3n2am0,a) left breast left modified radical mastectomy.b) left level 3.,received in : formalin procedure : modified radical mastectomy laterality : left total dimensions : medial to lateral :22cm superficial to deep :6 cm superior to inferior :16cmskin ellipse :12x6cm nipple :normalscar surgical defect :not seentumor : singletumor size : 5.5x4x2.5cm location of tumor : upper outer quadrant margins of tumor : ill defined deep margin : 0.5cm (musclemuscle : presentadjacent breast : fibrofatty tissue axillary tail : 7x7x3cmsize of largest node : 2.5x1x0.5cm. cut surface grey brown.,section sows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular or perineural invasion is not identified.,left breast left modified radical mastectomy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). tumor measures 5.5 in greatest dimension id located in the upper outer quadrant. ductal carcinoma in situ not seen. lymphovascular invasion is not seen. perineural invasion is not seen. posterior resection margin is free of tumor. nipple and areola is free of tumor.lymph nodes :fifteen lymph nodes are identified negative for malignancy(0 15).b) left level 3 lymph nodes : six lymph nodes are identified negative for malignancy(0 6).
MR1802798,left breast lump carcinoma breast.,left breast core biopsy.,received 5 grey white linear cores measures 0.8 0.9cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nucleus and moderate amount of cytoplasm.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1802830,sternal lesion malignant.,biopsy from sternal lesion,received multiple grey white linear cores measures 0.8 0.1cm. entire tissue processed.,section show linear cores of fibrocollagenous tissue with infiltrating lesion arranged in nests amp islands . the cells have round hyperchromatic nucleii with prominent nucleoli and moderate amount of cytoplasm . foci of necrosis noted.,biopsy from sternal lesion:suggestive of recurrence in a known case of carcinoma breast.
MR1802832,right breast lesion birads v.,right breast lesion.,received: 4 linear cores measures 0.8 1cm. entire tissue processed.,section shows multiple fragments of breast parenchyma showing infiltrating neoplasm arrangedin nests. the neoplastic cells are round oval with hyperchromatic nuclei scant to moderate cytoplasm. few cells show intracytoplasmic vacuolation .areas of hyalinization calcification noted. crush artifacts seen.,right breast lesion.invasive carcinoma with lobular featuresmodified bloom richardson score is 6 9. tubule formation :3.nuclear pleomorphism:2.mitotic figures :1 6 9
MR1802860,left breast lump carcinoma breast fibroadenoma.,biopsy from left breast lump.,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,section shows cores of breast parenchyma with lesion arranged composed of variable sized ducts lined by epithelial and myoepithelial cells.the epithelium shows stratification of epithelial cells and convulation. . stroma shows fibrosis with bland stroma cells. few ducts show inspissated secretions,biopsy from left breast lump:benign breast disease.suggestive of usual ductal hyperplasia.
MR1802869,left breast lump birads 5 carcinoma.,biopsy from left breast lump.,received 5 linear grey white to grey brown soft tissue bits each measures 0.5cm. entire tissue processed.,section shows cores of parenchyma with lesion arranged in sheets and nests.the cells have round hyperchromatic nuclei slightly eccentrically placed hyperchromatic nuclei and moderate amount of cytoplasm. stroma show desmoplasia. ductal carcinoma in situ noted.,biopsy from left breast lump:invasive carcinoma nst grade 2modified bloom richardson score is (3+2+1) 6 9dcis seen
MR1802878,right carcinoma breast.,a) right breast lumpectomy.b) right axillary sentinel node biopsy.,a) received fibrofatty tissue measures 6.5x5.5x2 cm cut section shows grey white tumor measures 1.8x1.3x1 cmwhich is located at the following distances from the respective margins:superior margin : 1 cminterior margin : 1.5 cmmedial margin : 1.3 cmlateral margin : 1.5 cmdeep margin : 0.4 cmb) received 2 fibrofatty tissue measures 2x1x0.8c.m. largest measures 1x0.5x0.3 c.m.cut surface shows grey white to grey brown entire tissue processed.,section shows breast parenchayma harbouring an infiltrating lesion arranged in acinar pattern and in cords. the tumor cells have moderately pleomorphic round nucleus dispersed chromatin prominent nucleoli and moderate cytoplasm.,a) right breast lumpectomy.invasive ductal carcinoma grade ll.modified bloom richardson score 6 9.tubule formation: 2nuclear pleomorphism :2.mitotic figures : 2.tumor measures 1.8 cm in greatest dimension.lymphovascular invasion is not present.all margins of resection are free of tumor.b) right axillary sentinel lymph node biopsy:four lymph nodes identified negative for malignancy. (0 4).
MR1802879,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 4 linear cores measures 0.8 1.0cm. entire tissue processed.,section show multiple linear cores of breast parenchyma with few compressed ducts and an infiltrating neoplasm arranged in nests and sheets the neoplastic cells are round to oval with vesicular nuclei scant to moderate clear cytoplasm prominent nucleoli. adjacent stroma shows lymphoplasmacytic infiltration.,biopsy from left breast lump:invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1802892,left breast lesion malignant,biopsy from left breast lesion.,received 4 linear cores measures 0.8 0.1cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm compressed sheets nests cords of atypical cells with moderate nuclear pleomorphism and increased mitosis . ductal carcinoma in situ. solid and comedo type noted.,biopsy from left breast lesion:invasive ductal carcinoma ( nos) with ductal carcinoma in situ comedo type. grade ii.modified bloom richardson score is (3+2+2)7 9
MR1802895,left breast lump malignant,left breast core biopsy,received 4 linear cores measures 0.8 to 1cm. entire tissue processed.,section shows cores of tissue showing fibrocollagenous tissue with few foci of tumor cells in nests and cords . individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy:suggestive of invasive ductal carcinomacomment: in view of small foci of tumor cells repeat biopsy is suggest for further hormonal studies.
MR1802899,left breast lesion malignant.,biopsy from left breast lesion.,received 4 linear cores measures 0.6 0.8cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in poorly formed tubular and nested pattern. the cells show moderate pleomorphism and increased mitotic figures. large areas of desmoplasia seen.,biopsy from left breast lesion:invasive carcinoma ductal ( nos) grade 1.modified bloom richardson score is (2+2+1(5 9).
MR1802905,carcinoma left breast.,left breast lesion core biopsy,received 4 linear cores measures 0.6 0.8 cm. entire tissue processed.,section shows cores of tissue cells in nests sheets and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lesion core biopsy:suggestive of invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1802919,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received 4 linear cores measures 0.6 to 0.7cm. entire tissue processed.,section shows tumor cells in diffuse sheets. individual cells have round to oval hyperchromatic nuclei and scant to moderate amount of cytoplasm.,right breast lump core biopsy:suggestive of poorly differentiated malignancy.suggest ihc for further confirmation.note : this an amended report which supersedes the earlier report.
MR1802947,right breast lump possibility of carcinoma breast,biopsy from right breast,received 4grey white linear cores measures 1 1.2 cm. entire tissue processed.,section shows breast parenchyma with lesion arranged in islands sheets. the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows desmoplasia with lymphocytic infiltrate.,biopsy from right breastinvasive carcinoma grade ii.modified bloom richardson score is(3+2+1) 6 9
MR1802964,right breast lump possibility of carcinoma breast.,biopsy from right beast lump.,received 4 linear cores measures 0.6 to 0.7cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in glands nests and cords . the cells show moderate pleomorphism and increased mitosis crush artefacts noted. stroma is dense and demoplastic.,biopsy from right beast lump.invasive carcinoma ( nst)nuclear grade ii
MR1803031,case of left breast lump under evaluation.,left breast wide excision.,wide local excision specimen of left breast measures 5x5x3cmskin ellips measures 4x1cmon serial section shows grey white firm circumscribed lesion measures 1.5x1x1cmdistance from margins:superior margin :2cminferior margin : 2cmmedial margin :1.5cmlateral margin : 1.5cmdeep margin : 1cm,section shows breast tissue with fairly circumscribed lesion composed of compressed ducts with preserved epithelial and myoepithelial layers . stroma show no atypia. few ducts show udh.sections from the inferior margin show intraductal papillomasection from lateral margin show papillary hyperplasia of ducts.no evidence of in situ or invasive carcinoma.,left breast wide excision:fibroadenoma with inferior margin showing intraductal papilloma
MR1803042,carcinoma left breast with left ovarian mass dermoid,b) hysterectomy with bilateral salpingo ooperectomy c) right pelvic peritoneal biopsyd) left pelvic peritoneal biopsye) right paracolic peritoneal biopsyf) left paracolic peritoneal biopsyg) omental biopsy.,b)uterus dimensions : midline fundal serosa to ectocervix : 7cmmaximum intercornual : 4.5cmmaximum anterior to posterior : 3cmcervix dimensions : 1.5x1.5cm ( anterior posterior x transverse) vaginal cuff : absentright ovary : present 4.5x4x3.5m description. uni loculated cut surface cystic amp solid measures 4x4x3.5 composed of pultaceous material with hair amp cartilageleft ovary : present 3.5x2.8x1.5cm description. cut surface unremarkableright fallopian tube : present 3cm description. cut surface dilated and hemorrhagicleft fallopian tube unremarkable : present 3.3 cm description. right parametrium : 1x0.8x0.5cmleft parametrium : 0.9x0.8x0.4 cmendometrial thickness :0.8cmmyometrium depth : anterior 1.5cm posterior1.6cmleiomyoma :nolower uterine segment :unremarkablec) received soft tissue bits measures 0.5x0.5x0.3cm. entire tissue processed.d) received single soft tissue bits measures 0.3x0.2x0.1cm. entire tissue processed.e) received single soft tissue bits measures 0.4x0.3x0.2cm. entire tissue processed.f) received soft tissue bits measures 0.4x0.3x0.2cm. entire tissue processed.g) received fibrofatty tissue measures 3x3x1.5cm. entire tissue processed.no deposit of seen.,b) hysterectomy with bilateral salpingo ooperectomy :left ovarian tumor: multiple section show keratinised cyst wall lined with ectodermal tissue consisting of squamous epithelium subepithelium shows normal adnexae sebaceaus glands hair follicles and in few areas mature mucus glands are seen.there is no inmature germ cells tissue present ovarian stroma shows spindle cells. there is no evidence of malignancy. mature cystic teratoma. right ovary: shows normal ovarian architecture with corpus albicans and spindle cell stroma. no evidence of malignancy.right and left fallopian tube: normal epitheliumcervix: normal squamous epithelium no dysplasia or malignancy.endocervix: normal endocervical glands.endometrium : tubular glands lined with cuboidal epithelial cells with compact stroma.myometrium :unremarkable.c) right pelvic peritoneal biopsy :fibrocollagenous and fibrofatty tissue. no evidence of malignancyd) left pelvic peritoneal biopsy:fibrofatty tissue no evidence of malignancye) right paracolic peritoneal biopsy:fibrofatty tissue no evidence of malignancy.f) left paracolic peritoneal biopsy:fibrofatty tissue no evidence of malignancyg) omental biopsy.fibrofatty tissue no evidence of malignancy,b) hysterectomy with bilateral salpingo ooperectomy with multiple:left ovarian tumor: mature cystic teratomaright ovary: no evidence of malignancyboth fallopian tube: normal epitheliumcervix : unremarkableendocervix: normal endocervixendometrium: proliferative phasemyometrium: unremarkablec) right pelvic peritoneal biopsy:no evidence of malignancyd) left pelvic peritoneal biopsyno evidence of malignancye) right paracolic peritoneal biopsy:no evidence of malignancyf) left paracolic peritoneal biopsy:no evidence of malignancyg) omental biopsy:no evidence of malignancy
MR1803052,left beast lump malignant.,biopsy from left breast lump,received 5 linear cores soft tissue bits measures each 0.5 1cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as ducts and tubules and cords. the neoplastic cells have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is elastatic..,biopsy from left breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1803090,left breast lump possibility of carcinoma breast,biopsy from left breast lump .,received 4 grey white soft tissue bits measures0.6 0.7cm. entire tissue processed.,section shows cores of fibrocollagenous tissue harboring an invasive neoplasm in nests cords and poorly formed tubules. the cells shows moderate nuclear pleomorphism and increased mitosis. stroma is desmoplastic.,biopsy left breast.invasive ductal carcinomas (nos) grade iimodified bloom richardson (3+2+2)7 9
MR1803107,left breast lump carcinoma breast.,left breast lump,received 4 grey white soft tissue bites measures 0.6 0.7 c.m. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a neoplasm arranged in acini and cords with areas of comedonecrosis. adjacent stroma areas of hyalinization. tumor cell are large having pleomorphic round nucleus dispersed chromatin prominent nucleoli and moderate cytoplasm. ductal carcinoma in situ component is present. solid pattern,left breast lump:invasive carcinoma no special type grade ll.modified bloom richardson score is 6(2+2+2).dcis presentlvi not seeen
MR1803118,right breast lump carcinoma breast,biopsy from right breast lump.,received multiple grey white linear cores measures 00.4 0.6cm. entire tissue processed.,section cores of fibro adipose tissue harboring an invasive neoplasm in nests sheets and cords. the cells show moderate nuclear pleomorphism with increased mitosis. necrotic areas present solid type . ductal carcinoma high grade seen.,biopsy from right breast lump:invasive carcinoma ductal( nos)modified bloom richardson score is( 3+2+2)7 9
MR1803126,right breast lump possibility of carcinoma breast.,right breast lump biopsy.,received 4 linear cores measures 0.5 0.6cm. entire tissue processed.,section studied show linear cores of breast parenchyma harboring a neoplastic lesion arranged in nests islands and cords. the lesional cells are pleomorphic with round to oval hyperchromatic nuclei and moderate eosinophilic cytoplasm. mitosis are 6 10 hpf . stroma shows sclerosis.,right breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7( 3+2+2).
MR1803149,carcinoma left breast,a) left breast wide excisionb) revised medial marginc) level i ii iii axillary clearance,a) received left breast measures 7x5x5cm skin ellips measures 4x2cm.on small section grey white lesion measures 2.1x1.5x1cm. entire tissue processeddistance from marginssuperior margin: 1cminferior margin : 1.3cmmedial margin : 0.1cmlateral margin :3cmdeep margin : 1.5cmb) received fibrofatty tissue measures 3.5x3x1cm one surface inked .c) received fibrofatty tissue measures 7x5x4cm.largest lymph nodes measures 1.5x1x1cm. cut surface grey white.,section from the breast lesion show invasive ductal carcinoma with foci of ductal carcinoma comedo type.,a) left breast wide excision:invasive ductal carcinomamodified bloom richardson score is 2+2+2 6 9 grade iitotal size of the tumor is 2.1cminvasive carcinoma measures 1.2cm in greatest dimension.ductal carcinoma in situ solid cribriform and comedo type seen measures 0.9cm.lymphovascular invasion indeterminateperineural invasion not identified.superior inferior and lateral margins are free of tumorb) tissue labelled as revised medial marginshows invasive carcinoma however the inked surface is free of tumorc) lymph nodes : i8 nodes isolated 7 nodes show tumor depositlargest deposit measuring 0.5cm .extranodal spread not seen.summary:left breast wide excision and axillary dissection invasive ductal carcinoma grade ii7 out of 18 nodes show tumor deposit.resected margins are free of tumor.
MR1803157,carcinoma left breast,a)left breast wide excision of lump.b)left axillary sentinel nodes,a) received left breast lumpectomy measures 5.5x4x2.8cm.skin ellipse measures 3x0.9cm. cut surface grey white firm lesion identified measures 1.2x1x0.6cm distance of the tumor from respective margins:superior margin: 1.8cminferior margin : 1cmmedial margin: : 1.5cmlateral margin : 2.5cmdeep margin :2.5cmb)received fibrofatty tissue measures 4x3x1cm.entire tissue processed.isolated 2 lymph nodeslargest lymph nodes measures 2.3x1x0.8cm( inked) cut surface unremarkable.,multiple section studied show breast parenchyma harboring a lesion arranged in nests cords and occasional tubules of neoplastic epithelial cells exhibiting increased nucleo cytoplasmic ratio pleomorphic vesicular nuclei prominent nucleoli and moderate to abundant amount of pale eosinophilic cytoplasm. the intervening stroma shows presence of dense fibrocollagenous connective tissue. extensive ductal carcinoma in situ(dcis) component is noted. lymphovascular emboli is seen. perineural invasion is seen. the overlying skin is uninvolved by tumor. all the margins that is superior inferior medial lateral and deep are uninvolved by the tumor.b)three lymph nodes identified are free of tumor.,a)left breast wide excision of lump:invasive ductal carcinoma nos grade iimodified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2tumor measures 1.2cm in maximum dimension.high grade ductal carcinoma in situ (comedo pattern) is seen. ductal carcinoma in situ component measures 0.5cm in maximum dimension.lymphovascular emboli and perineural invasion identified.all margins of resection including deep are free of tumor.b)left axillary sentinel nodes:three lymph nodes identified free of tumor(0 3)
MR1803175,right brest lump carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measure 0.7 1 cm.entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in cords few tubules and singly scattered.the lesional cells are round to oval having hyperchromatic nuclei and scant to moderate cytoplasm. few showing vacuolated cytoplasm. stroma shows hyalinization cells exhibit moderate nucleate pleomorphism mitoses discerned. crush artifacts noted.,right breast lump biopsy.invasive carcinoma no special type grade iimodified bloom richardson score 6(3+2+1)dcis not seen.lvi not seen
MR1803234,known case of carcinoma breast left,a) skin nodule at left side of neck.b) biopsy from right breast.,a) received four grey white to grey brown linear cores measures 0.4 0.8cm. entire tissue processed.b) received multiple grey white to grey brown linear cores measures 1 1.2cm. entire tissue processed.,a) section snows linear cores harboring an infiltration lesion arranged in cords of neoplastic cells exhibiting increased nucleo cytoplasmic ratio pleomorphic hyperchromatic nuclei inconspicuous nucleoli and scant cytoplasm. the intervening stroma shows presence of dense fibrocollagenous connective tissue.b) section snows linear cores harboring an infiltration lesion arranged in cords of neoplastic cells exhibiting increased n c ratio pleomorphic hyperchromatic nuclei inconspicuous nucleoli and scant cytoplasm. the intervening stroma shows presence of dense fibrocollagenous connective tissue.,a) left skin nodular nodule at neck:poorly differentiated malignancy favor metastatic deposit in a known case of carcinoma breast.b)biopsy from right breast:invasive carcinoma breast lobular grade 2suggest ihc
MR1803245,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received 5 grey white linear cores measures 1 1.2cm. entire tissue processed.,section show linear cores of breast parenchyma harboring an invasive neoplasm in nests and poorly formed glands. the cells show moderate to abundant eosinophilic cytoplasm moderate nuclear pleomorphism and prominent nucleoli. stroma is desmoplastic,biopsy from left breast lump:invasive carcinoma nst grade iimodified bloom richardson score is (3+2+1)6 9
MR1803249,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received 5 grey white linear score 0.5 0.8 cm entire tissue processed.,section show linear cores of tissue harboring a neoplastic lesion arranged in nest and sheets. the cells are moderately pleomorphic with round to oval hyperchromatic nuclei few having prominent nucleoli and moderate amount of cytoplasm. stroma show dense lymphoplasmacytic infiltrate. few multi nucleate tumor giant cells seen. mitotic figures discerned.,right breast lump core biopsy:invasive carcinoma nst grade 2.modified bloom richardson score (3+2+1).areas of necrosis seen.
MR1803252,left breast lump possibility of carcinoma breast.,left breast lump biopsy,received 3 grey white linear cores measures 0.8 1cm. entire tissue processed.,section studied show linear cores of breast parenchyma showing scattered tubules cords and islands of neoplastic cells with moderate eosinophilic cytoplasm pleomorphic hyperchromatic nuclei. stroma shows elastosis. mitosis are discerned.,left breast lump biopsy:invasive ductal carcinoma grade 1. modified bloom richardson score is 5(3+2+1).
MR1803262,left breast lump possibility of carcinoma breast.,left breast lump biopsy,received 3 grey white linear cores measures 0.8 1cm. entire tissue processed.,section studied show linear cores of breast parenchyma harboring an infiltrating lesion arranged in nests and islands. the lesional cells are large with abundant amount of eosinophilic cytoplasm pleomorphic hyperchromatic nuclei. areas of necrosis seen. stroma is desmoplastic.,left breast lump biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1803273,left breast lump possibility of carcinoma breast.,left breast lump biopsy:,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,section studied show multiple cores of breast parenchyma harboring a neoplastic lesion arranged in cords tubules and islands . the lesional cells have moderate amount of cytoplasm oval to spindle hyperchromatic nuclei. mitosis are discerned. focus of ductal carcinoma in situ seen solid type.,left breast lump biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1803294,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 0.7 1cm. entire tissue processed.,section sows linear cores of breast parenchyma harboring a lesion arranged in vague tubules cords and nests comprising of atypical cells having pleomorphic ovoid dark nuclei and moderate eosinophilic cytoplasm. mitotic figures discerned 15 16 10 hpf. stroma shows fibrosis and focal lymphoplasmacytic infiltrate.,biopsy from right breast lump:invasive ductal carcinoma grade iii.modified bloom richardson score is 3+2+3 8 9
MR1803310,left breast lump carcinoma breast,biopsy from left breast lump.,received 4 linear grey white soft tissue bits each measures 0.5 0.8cm. entire tissue processed.,section shows linear cores tissue harboring a neoplastic lesion arranged in nests small aggregates with reaction spaces. the cells have round hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows desmoplasia with lymphocytic infiltrates.,biopsy from left breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is (3+2+1)6 9.
MR1803319,right breast lump possibility of carcinoma breast.,biopsy from right breast,received 5 grey white linear cores measures 0.4 0.6 cm. entire tissue processed.,section shows linear cores of breast parenchyma. with lesion arranged in islands and sheets. the cells have moderately pleomorphic round vesicular nuclei prominent nucleoli and moderate amount of cytoplasm. stroma show desmoplasia with lymphoplasmacytic infiltrate perineural invasion noted.,biopsy from right breastinvasive ductal carcinoma grade ii.modified bloom richardson score is(3+2+2)7 9.
MR1803348,known case of right breast. right breast lesion residual lesion.,right breast lesion biopsy.,received three grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section shows tumor cells in sheets and abortive glandular pattern. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive carcinoma grade 2. modified bloom richardson score is 6(2+3+1).
MR1803360,right breast lump possibility of carcinoma breast.,biopsy from right breast,received 4grey white linear cores measures 0.8 1 cm. entire tissue processed.,section shows linear cores of tissue with lesion arranged in nest and sheets. the cells have moderately pleomorphic round hyperchromatic nuclei and prominent nucleoli and moderate amount of cytoplasm. stroma shows lymphocytic infiltrate and desmoplasia mitotic figures discerned.,biopsy from right breastinvasive carcinoma nst grade ii.modified bloom richardson score is(3+2+1)6 9.
MR1803383,right breast lump carcinoma breast.,biopsy from left breast lump.,received 5 grey white linear cores measures 0.6 1cm. entire tissue processed,section sows cores of breast tissue harboring an invasive neoplasm in cords nests and poorly formed tubules . the cells show moderate pleomorphism and hyperchromatic nuclei. stroma is desmoplastic .small focus of ductal carcinoma (solid type noted).,biopsy from left breast lump:invasive carcinoma nst grade 3.modified bloom richardson score is 3+3+2 8 9
MR1803395,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.left axillary lymph node,a) received 3 grey white linear cores measures 1 1.2cm. entire tissue processedb)received 3 grey white linear cores measures 1 1.5cm. entire tissue processed,section shows cores of breast tissue harboring an invasive neoplasm in diffuse sheets of atypical cells with moderate cytoplasm pleomorphic hyperchromatic nuclei with prominent nucleoli admixed with extensive lymphoplasmacytic infiltrate foci of lymphovascular invasion present in section from left breast,a amp b) biopsy from left breast lump and left axillary lymph node:poorly differentiated malignancy high grade. biopsy from breast and axillary lymph nodesuggest ihc.
MR1803415,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received 4 grey white linear cores measures 0.5 1cm. entire tissue processed.,section studied show cores of breast parenchyma harboring a neoplastic lesion arranged in sheets cords and islands. the lesional cells have moderate amount of eosinophilic cytoplasm pleomorphic vesicular nuclei and prominent nucleoli. mitoses are discerned. stroma shows fibrosis. lymphovascular invasion not seen.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1803416,right breast lump possibility of carcinoma breast.,biopsy from right breast,received 5 grey white linear cores measures 1to 1.2 cm. entire tissue processed.,section shows linear cores of tissue parenchyma lesion arranged in small nest and cords. the cells have moderate pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows large areas of desmoplasia.,biopsy from right breastinvasive carcinoma grade ii.modified bloom richardson score is(3+2+1) 6 9.
MR1803440,right breast lump possibility of malignant lesion,biopsy from right breast lump.,received multiple grey white linear cores measures 0.5 1cm. entire tissue processed.,section shows linear cores breast parenchyma infiltrated by neoplastic cells arranged in tubules and cores. the lesion cells have round to irregular nucleus dispersed chromatin prominent nucleoli and moderate cytoplasm. ductal carcinoma in situ ( solid type) is present. mitosis is discerned.,biopsy from right breast lump:invasive carcinoma with ductal carcinoma in situ grade 2.modified bloom richardson score : 2+2+2 6 9.
MR1803455,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received 3 grey white to grey brown linear cores measures 0.7 1cm. entire tissue processed.,section sows linear cores of tissue arranged in cribriform pattern. nest and sheets. the cells have round dark nuclei and moderate amount of cytoplasm . the nest are lying in the pale mucinous background . stroma shows fibrosis with lymphocytic infiltrate.,biopsy from right breast lump:invasive carcinoma with mucinous component 30 nuclear grade ii
MR1803461,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,section sows linear cores of tissue harboring a lesion arranged in nests and cords comprising of neoplastic cells having round to oval pleomorphic hyperchromatic nuclei conspicuous nucleoli and moderate eosinophilic cytoplasm. some cells have clear cytoplasm with distinct borders. mitotic figures discerned 12 15 10 hpf along with few atypical mitosis. stroma shows hyalinisation and fibrosis.,biopsy from left breast lump:invasive ductal carcinoma grade iii.modified bloom richardson score is 3+2+3 8 9
MR1803475,left breast lump possibility of carcinoma breast.,left breast core biopsy.,received 3 grey white linear cores measures 1 1.5cm. entire tissue processed.,section shows breast parenchyma with lesion composed extensive are areas of ductal carcinoma in situ with increased foci composed of nest of neoplastic having vesicular nuclei prominent nucleoli and moderate amount of cytoplasm. mitotic figures discerned. stroma sows lymphoplasmacytic infiltrated around the ducts and granulomata,left breast core biopsy:invasive carcinoma grade ii.modified bloom richardson score is (3+2+1) 6ductal carcinoma in situ solid high nuclear grade seen.
MR1803479,right breast lump carcinoma breast.,biopsy from right breast lump.,received 3 grey white linear cores measures 1 1.2cm. entire tissue processed.,section show linear cores of tissue composed of infiltrating neoplastic lesion arranged in nest islands. the cells have moderate amount of cytoplasm. stroma shows desmoplasia. mitotic figures noted.,biopsy from right breast lump:invasive carcinoma nst grade iimodified bloom richardson score is (3+2+2)7 9
MR1803480,right breast lump possibility of carcinoma breast..,right breast core biopsy.,received 4 grey white to grey brown linear cores measures 0.5 0.7cm. entire tissue processed.,section shows linear cores of tissue composed of neoplastic lesion arranged in papillae with fibrovascular core nest and sheets. the cells have moderate pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. areas of necrosis seen. mitotic figures discerned,right breast core biopsy:invasive carcinoma of ductal type grade iiimodified bloom richardson score is8 (3+2+3).large areas of necrosis seen.
MR1803481,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 0.4 1cm. entire tissue processed.,section sows linear cores of breast parenchyma infiltrating by nests and cords of neoplastic cells having pleomorphic hyperchromatic nuclei with moderate eosinophilic cytoplasm. mitotic figures 8 10 10 hpf and stroma show extensive fibrosis scattered lymphocytes and plasma cells .,biopsy from left breast lump:invasive ductal carcinoma grade iimodified bloom richardson score is (3+2+2)7 9 .
MR1803519,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 0.7 1cm. entire tissue processed.,section sows linear cores of breast tissue parenchyma a lesion arranged islands and sheets comprising of neoplastic cells having pleomorphic ovoid dark nuclei prominent nucleoli and moderate eosinophilic cytoplasm. mitotic figures are 7 8 10 hpf. adjacent breast parenchyma shows fibrosis and lymphoplasmacytic infiltrates.,biopsy from left breast lump:invasive ductal carcinoma grade iimodified bloom richardson score is 3+2+2 7 9 .
MR1803550,carcinoma left breast post nact.,a) left breast left breast conservation surgery.b) left axillary lymph node dissection.,a) received specimen measures 8 x 6.5 x 5 cm. skin ellipse measures 2 x 0.5 cm. on serial section no mass lesion identified. few identified grey white areas noted measures 2 x 1 x 0.5 cm.distance from different margins :superior margin : 1.2 cminferior margin : 2 cmmedial margin : 2 cmlateral margin : 3 cmdeep margin : 1.8 cmb) received fibrofatty tissue measures 8x8x2 cm. largest lymph node measures 1.2x1x1 cm. cut surface shows grey brown.,sections shows breast parenchyma with maintained luminal and tubular ductal with lined by luminal and abluminal cells. adjacent stroma shows lymphoplasmacytic infiltrates and no evidence of malignancy seen.,a) left breast left breast conservation surgery : no residual tumor seen. treatment related changes are seen. all margins of resection are free of tumor.b) left axillary lymph node dissection : ten lymph nodes identified are free of tumor (0 10).pathological stage : ypt0n0
MR1803567,right breast mass carcinoma breast.,right breast mass biopsy.,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,section sows linear cores of tissue with lesion arranged in infiltrating cords and small nest. the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows desmoplasia with scattered inflammatory cells.,right breast mass biopsy:invasive carcinoma nst grade iimodified bloom richardson score ( 3+2+1) 6 9.
MR1803577,birads 4 with lesion in right breast.,right breast core biopsy.,received 4 grey white linear cores measures 0.7 1cm. entire tissue processed.,section shows linear cores of lesion arranged in sheets nest and vague papillary pattern. the cells have round moderate pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. interspersed lymphoplasmacytic infiltrate noted. brisk mitotic activity noted. .,right breast core biopsy:invasive carcinoma nst grade iiimodified bloom richardson score is (3+2+3) 8 9.
MR1803583,left breast lump carcinoma breast.,left breast lump core biopsy.,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma with lesion composed of spindle cells arranged in interlacing fascicles . the cells have oval dark nuclei and moderate amount of cytoplasm. interspersed dilated few congested blood vessels seen. focal myxoid change noted. no atypia is seen.,left breast lump core biopsy.spindle cell lesionthe possibility considered are 1) cellular fibroadenoma phyllodes tumor.suggest wide excision
MR1803585,known case carcinoma left breast.,a) wide excision b) revised deep margin.c) deep and lateral margins,a) received wide local excision lumpectomy specimen measures 6x4.2x12.5cmskin ellips measures 6x4cm. on solid section grey white from to hard lesion measures 2.5x2x1.5cm.distance from marginssuperior margins : 0.5cminferior margin :1.7cmmedial margin 2cmlateral margin : 1.5cmdeep margin : 1cmb) received tissue measures 7x4x1.5cmc) received single tissue bits measures 3x2x1cm.,a) tumor is composed of pleomorphic cells with hyperchromatic nucleus and scanty cytoplasm. the tumor cells are present in diffuse sheets and clumps surrounded by fibrous stroma . tubular formation less than 10 (3) mitotic figures 8 10(2) nuclear pleomorphism 2lymphovascular invasion indeterminate.superior margins : free of tumorinferior margin :free of tumormedial margin free of tumorlateral margin : free of tumordeep margin : close to the resected marginb) surrounding tumor cells are present how ever the inked margins away from the tumor.c) shows muscle bundle free from the tumor.,wide local extension:invasive ductal carcinoma nuclear grade iitumor measures 2.5 cm lymphovascular invasion indeterminatesuperior inferior lateral medial margins are free of the tumorresected deep and lateral margins are free of the tumor.
MR1803605,right central and outer quadrant breast lesion birads 4,right breast core biopsy.,received 7 grey white linear cores measures 0.7 1cm. entire tissue processed.,section shows hyperchromatic ductules having solid and papillary pattern lined by cells with hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :shows ductal carcinoma in situ of solid and papillary pattern with intermediate nuclear grade. no definite evidence of invasive malignancy seen in the tissue submitted.suggest excision of lump or repeat biopsy for further confirmation in invasive component.
MR1803619,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,section shows cores of breast tissue scattered ducts with epithelial and myoepithelial hyperplasia.stroma is edematous shows extensive hyalinisation. no evidence of in situ or invasive carcinoma in the section examined.,biopsy from right breast:scattered ducts with hyperplasiano evidence of malignancy in sections studied please repeat biopsy if clinically indicated.
MR1803642,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received 3 grey white linear cores measures 1 1.2cm. entire tissue processed.,section shows linear cores of tissue with lesion arranged in nest islands sheets. the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. stroma show desmoplasia with inflammatory infiltrate. areas of necrosis and karyorrhectic noted mitotic figures discerned.,biopsy from left breast:invasive ductal carcinoma grade iimodified bloom richardson score is (3+2+1) 6 9
MR1803643,right breast lesion 12 1 0 clock.,biopsy from right breast.,received 5 grey white linear cores measures 0.8 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a neoplasm arranged in tubules cords and nests. the lesional cells have hyperchromatic round to irregular nucleus and moderate cytoplasm. mitosis id discerned.,biopsy from right breast:invasive carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism :2mitotic figures : 2 7 9
MR1803653,left breast lump possibility of carcinoma breast.,left breast lump core biopsy.,received 4 grey white linear cores measures 0.5 0.8cm. entire tissue processed.,section shows tumor cells in diffuse sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. areas of necrosis are seen.,left breast lump core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1803685,left breast lump carcinoma.,biopsy from left breast.,received 5 grey white linear cores measures 1 1.2cm. entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged as islands and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. adjacent breast shows fibrocystic change,biopsy from left breast:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2
MR1803709,left breast lump possibility of carcinoma breast,left breast lump core biopsy.,received 4 grey white linear cores measures 1 1.5cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in nests cords and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1803719,right breast lump possibility of carcinoma breast.,right breast core biopsy.,received 5 grey white to grey brown linear cores measures 0.8 1.2 cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1803727,left breast lump possibility of carcinoma breast.,left breast core biopsy.,received 4 grey white linear cores measures 0.7 1cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cell in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1803738,carcinoma right breast ct2n0m0,a) right sentinel lymph nodeb) wide local excision right breast lumpc) revised deep margin,a) received fibrofatty tissue measures 3x2x1cm isolated 2 lymph node.largest lymph node measures 0.8x0.7x0.6cmb) received wide local excision specimen measures 8x5x5cmskin ellipse measures 7x1.5cm cut surface cyst measures 4x4x3.5cmdistance from marginssuperior margin: 2cminferior margin :2.5cmmedial margin :2.5cmlateral margin :3cmdeep :0.2cmc) received fibrofatty tissue measures 2x1.5x1cmshows muscle bundle.,a) right sentinel lymph node: 2 nodes no deposit of tumor.b)tumor composed of pleomorphic cells with hyperchromatic nucleus with syncitial cytoplasm. dense lymphoplasmacytic infiltration is present surrounding the tumor .the tubule formation less than 10 (3) mitosis (2) anaplasia (2) modified bloom richardson score is 7 9 grade ii.ductal carcinoma in situ not present.lymphovascular invasion not present.perineural invasion presentall resected margins are free of tumorc)revised deep margin muscle bundle free of tumor.,wide excision breast :maximum dimension of tumor is 4x4cm.ductal carcinoma in situ not present.lymphovascular invasion not present.perineural invasion presentresected margin superior inferior medial lateral margins are free of tumor.revised deep margin is free of tumorsentinel lymph nodes: 2 nodes no deposit of tumor.pathological stage: pt2n0.
MR1803803,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma with a lesion arranged in islands nest and sheets. the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm cytoplasm. stroma shows desmoplasia with lymphocytic infiltrate mitotic figures discerned.,biopsy from right breast lump:invasive carcinoma nst grade ii.modified bloom richardson score is (3+2+1)6 9.
MR1803842,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received 4 grey white linear cores measures 0.7 1m. entire tissue processed.,section shows linear cores of tissue with lesion arranged in nests with retraction spaces . the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows extensive desmoplasia. mitotic figures seen.,right breast lump core biopsy:invasive carcinoma nst grade iimodified bloom richardson score is (3+2+1)6 9.
MR1803857,right breast lump carcinoma breast.,right breast lump biopsy.,received 4 grey white linear cores measures 0.7 1cm. cut surface grey white.,section shows cores of fibro adipose tissue harboring an invasive neoplasm in sheets and nests the cells show moderate cytoplasm. moderate nuclear pleomorphism and increased mitosis. stroma is desmoplastic.,right breast lump biopsy:invasive ductal carcinoma(nst)modified bloom richardson score is (3+2+2) 7 9 grade 2.
MR1803880,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received 5 grey white to grey brown linear cores measures 0.7 1cm. entire tissue processed.,section shows multiple linear cores with a lesion arranged in nests sheets and individual s cells. the cells are round to oval scant to moderate cytoplasm few with prominent nucleoli adjacent stroma shows few inflammatory infiltrates composed of lymphocytes. mitotic figures discerned. areas of necrosis seen.,biopsy right breast lump:invasive carcinoma nst modified bloom richardson score is (2+3+1)6 9
MR1803905,swelling left breast.,left breast excision biopsy.,received globular fibrofatty tissue measures 4.5x4x2.8cm grey white lobulated cut surface shows distance infiltrative soft to firm lesion measuring 2 x 1 x 0.5 cm. distance from closest nearest margin is 0.1cm. entire tissue is submitted.,section shows breast parenchyma harboring infiltrating lesion arranged in nests and cords in lying in pools of mucin. the cells are round to oval having vesicular nuclei and prominent nucleoli and moderate amount of cytoplasm. mitoses discerned. intervening stroma shows lymphoplasmacytic infiltrate.,left breast excision biopsy:suggestive of mucinous carcinoma grade 2. modified bloom richardson score is 6(3+2+1). tumor measures 1.5 cm in greatest dimension( microscopically). lymphovascular invasion is not identified. perineural invasion is not identified. margins of resection are free of tumor.
MR1803920,case of right breast carcinoma,a) blue hot nodeb) non blue non not node.c)right mastectomy.,a) received fibrofatty tissue measures 1x1x0.5cm1 lymph node identified measures 0.5x0.5x0.5cm entire tissue processed.b) received fibrofatty tissue measures 2.5x1.8x1cmlargest lymph node measures 0.8x0.6x0.6cm. cut surface fatty infiltrated.c) received in : formalinprocedure : mastectomy ( post lumpectomy). laterality : righttotal dimensions : medial to lateral :14cm superficial to deep :4cm superior to inferior :12cmskin ellipse :13x9cmnipple :normalscar surgical defect : present in lower outer quadrant measures 3.5cmtumor : grey white fibrotic area measures 2.5x2x2cmlocation of tumor :lower outer quadrantmargins of tumor : ill defined deep margin : 0.2cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail : absent,section from the breast parenchyma shows a lesion arranged in sheets. the cells shows a lesion arranged in sheets. the cells foaming the lesion are round to oval nuclei abundant granular cytoplasm prominent nucleoli lymphoplasmacytic infiltrates are seen. mitotic figures are seen. areas of necrosis with foreign body giant cell reaction.,a) blue hot node right axillary sentinel lymph node:isolated 1 lymph node shows no metastatic deposit b) non blue non not node right axillary lymph node:isolated 5 lymph node shows no metastatic deposit.c)right breast right mastectomy:residual invasive ductal carcinoma grade ii.modified bloom richardson score is 7 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2tumor measures 2.5cm in greatest dimension is located in the lower outer quadrant.ductal carcinoma in situ not seen.lymphovascular invasion not identified.perineural invasion not identifiedposterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes 6 lymph nodes metastasis. nil (0 6).right sentinel 6 nodes isolated all are free of tumor.summary:right mastectomy residual infiltrating ductal carcinoma grade ii.
MR1803950,carcinoma right breast,a) right modified radical mastectomyb) right level 3,a) received in : formalin procedure :modified radical mastectomy laterality : right total dimensions : medial to lateral :23cm superficial to deep :5 cm superior to inferior :3cmskin ellipse :12x10cm nipple :normalscar surgical defect :not seentumor : singletumor size : 2.0x2.0x2cm location of tumor : outer upper quadrant margins of tumor : ill defined deep margin : 2cmmuscle : not identifiedadjacent breast : fibrofatty tissue axillary tail :5x3x2cmlevel i ii lymph nodes : 11 nodeslevel iii nodes :7 nodessize of largest node : 2.5x1x2cm . cut surface grey white.b) received single fibrofatty tissue measures 3x3x2cm.isolated 7 nodes .larger lymph node measures 0.5x0.5x0.5cm,tumor bed:total size of the tumor is 2cminvasive ductal carcinoma is 1.5cmductal carcinoma in situ is 0.5cm comedo type high grade,right breast right modified radical mastectomy.modified bloom richardson score is 7 9 grade ii.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2tumor measures 2x2cm in greatest dimension is located in the outer upper quadrant.ductal carcinoma in situ present with comedonecrosis measuring 0.5cm.lymphovascular invasion present.perineural invasion not identified.posterior resection margin is free of tumor.nipple and areola is unremarkablelevel i ii lymph nodes 3 nodes show metastatic deposit of tumor out of 11 nodes (3 11).perinodal spread presentlevel iii nodes 7 nodes no deposit of tumorpathological state pt1n1summary:right modified radical mastectomy invasive ductal carcinoma grade iilevel i ii lymph nodes 3 nodes show metastatic deposit of tumor out of 11 nodes (3 11).perinodal spread presentlevel iii nodes 7 nodes no deposit of tumor
MR1803980,right breast lump possibility of carcinoma breast.,right breast core biopsy.,received 4 grey white linear cores measures 0.7 1cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cell in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1804000,left breast lump carcinoma breast.,left breast lump biopsy.,received 4 grey white linear cores measures 0.7 1cm. cut surface grey white.,section shows breast parenchyma harboring an invasive neoplasm composed of cells in cords and nests and vague tubules with moderate nuclear pleomorphism and hyperchromatism. there is increased mitosis,left breast lump biopsy:invasive carcinoma(nst)modified bloom richardson score is (2+2+1) 5 9 grade i.
MR1804025,right breast lump possibility of carcinoma breast.,biopsy from right breast core biopsy.,received 4 grey white linear cores cores measures 1to 1.2cm. entire tissue processed.,section show linear cores of tissue with an infiltrating neoplastic lesion arranged in nest cords and sheets. the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows extensive desmoplasia with few lymphocytic infiltrate.,biopsy from right breast core biopsy:invasive carcinoma nst grade 2modified bloom richardson score is (3+2+1) 6 9.
MR1804040,known case of carcinoma breast.,biopsy from interscapular nodule.,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in cords and tubules. the cells have pleomorphic round to irregular hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm.,biopsy from interscapular nodule:metastatic carcinoma in a known case of carcinoma breast.suggest further work up
MR1804058,right breast lump possibility of carcinoma breast.,biopsy left breast lump.,received 4 grey white linear cores measures 0.8 1cm. entire tissue processed.,section from the breast parenchyma shows a lesion arranged in tubules and abortive papillary pattern.the lesionoal cells are round to oval hyperchromatic nuclei with nuclei showing prominent nucleoli abundant eosinophilic cytoplasm. adjacent stroma shows lymphocytic infiltrates. brisk mitotic figures are seen.,biopsy right breast lump:invasive carcinoma nst grade 2modified bloom richardson score is (2+2+2)6 9
MR1804072,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received 4 grey white linear cores measures 0.5 0.7cm. entire tissue processed.,section from the breast parenchyma show a lesion arranged in nests. the glands are lined by inner luminal cells and outer abluminal cells . few ducts show hyperplasia with myxoid cellular stroma shows inflammatory infiltrate composed of lymphocytes .no evidence of malignancy seen,biopsy from left breast lump:benign breast disease suggest intoto excision to rule out biphasic neoplasm
MR1804186,right breast lump birads and lesion.,right breast lump biopsy.,received 4 grey white linear cores measures 0.4 1cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a neoplastic foci arranged in islands having pleomorphic cells with irregular round to oval dark nuclei conspicuous nucleoli and moderate eosinophilic cytoplasm. mitotic figures discerned 6 8 10 hpf. adjacent breast parenchyma shows ductal hyperplasia and stroma fibrosis.,right breast lump biopsy:shows extensive areas of ductal carcinoma in situ of solid and cribriform pattern( intermediate nuclear grade) with foci of invasion.
MR1804201,left breast lump possibility of carcinoma breast,biopsy from left breast lump.,received 3 grey white linear cores measures 1 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring irregular islands of neoplastic cells having pleomorphic ovoid dark irregular nuclei prominent nucleoli and moderate cytoplasm. mitotic figures fobrosis and extensive inflammatory infiltrate comprising of lymphocytes and plasma cells. hyalinised blood vessels noted.,biopsy from left breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation :3nuclear pleomorphism:2mitotic figures : 2 7 9
MR1804210,left breast lump malignant,biopsy from left breast mass.,received 5 grey white linear cores measures 1 1.2cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in cords sheets and nests. the cells are ovoid having moderate amount of pale eosinophilic to clear cytoplasm and hyperchromatic nucleus. mitotic figures are discerned. stroma shows desmoplasia with lymphomononuclear infiltrates. congested blood vessels and aras of hemorrhage seen.,biopsy from left breast mass:invasive carcinoma nst grade 2modified bloom richardson score is 6 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1804232,left breast lump possibility of carcinoma breast.,left breast core biopsy.,received 3 grey white linear cores measures 1.2 1.5 cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in cords and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy:invasive carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1804243,left breast lump possibility of carcinoma breast,biopsy from left breast lump.,received 3 grey white linear measures 1 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a neoplastic lesion arranged in vague tubules cords and comprising of cells having round to oval dark pleomorphic nuclei and moderate pale eosinophilic cytoplasm. stroma shows extensive hyalinisation and scattered lymphocytes..,biopsy from left breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is (3+2+1)6 9.
MR1804253,left breast lump possibility of carcinoma breast.,left breast biopsy.,received 3 grey white linear cores measures 0.4 1cm. entire tissue processed.,section shows cores of fibrous adipose tissue harboring an invasive neoplasm in tubules nests and cords the cells show moderate pleomorphic and moderate eosinophilic cytoplasm. stroma is desmoplastic,left breast biopsy:invasive carcinoma nstmodified bloom richardson score (3+2+1)6 9.grade ll
MR1804266,left breast lump possibility of carcinoma breast.,left breast biopsy.,received 4 grey white linear cores measures 0.8 1cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm composed of cells in tubules cords and nests. the cells show moderate pleomorphism and clear to eosinophilic to clear cytoplasm. small focus of ductal cribriform type noted. foci of lymphovascular invasion present.,left breast biopsy:invasive carcinoma nst grade 2.modified bloom richardson score (3+2+2)7 9.
MR1804273,left breast lump possibility of fibroadenoma carcinoma breast.,left breast core biopsy.,received 3 grey white linear cores measures 0.5 0.7cm. entire tissue processed.,section shows fibrocollagenous tissue with few ductules lined by luminal and abluminal cells. no atypia is seen.,left breast core biopsy:shows benign breast tissue.negative for malignancy.
MR1804313,left breast lesion malignant,biopsy from left breast.,received 5 grey white to grey yellow linear cores of 1 1.2cm. entire tissue processed.,section shows cores of fibro adipose harboring an invasive neoplasm composed of clusters of cells floating in pools of mucin. the cells shows moderate to mild pleomorphism round to oval hyperchromatic nuclie and eosinophilic granular cytoplasm.,biopsy from left breast:invasive carcinoma with mucinous featuresnuclear grade ii
MR1804337,right breast lump carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,section shows breast tissue harboring an invasive neoplasm in cords nests of cells that show moderate nuclear pleomorphism and increased mitosis .stroma is desmoplastic.,biopsy from right breast:invasive carcinoma nstmodified bloom richardson score is (3+2+1)6 9 grade ii.
MR1804364,right breast lump carcinoma breast.,right breast lesion core biopsy.,received 4 grey white linear core measures 0.7 1 cm entire tissue processed.,section shows linear cores of tissue with lesion arranged in nests cords and sheets. the cells have round moderately pleomorphic nuclei and moderately pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows desmoplastic mitotic figures discerned.,right breast lesion core biopsy:invasive carcinoma nst grade ii.modified bloom richardson score (3+2+1) 6 9.
MR1804388,cas4e of left breast carcinoma,a) left breast wide excision.b) left axillary dissection.,a) received lumpectomy specimen measures 8.5x6x3cmskin ellipse measures 6.5x1cmcut surface grey white soft lesion measures 3.5x2.5x2.5cm distance from marginssuperior margin: 2.5cminferior margin :1 cmmedial margin :2 cmlateral margin : 1cmdeep margin : 1.5cmb) received fibrofatty tissue measures 6.5x6x2cm.largest lymph nodes measures 1.5x1x0.4cm. cut surface grey white.,a) residual viable tumor presentinvasive ductal carcinoma. surrounding the tumor areas of fibrosis cellular infiltration present.tubule formation 2 mitotic figures 2 nuclear pleomorphism 2modified bloom richardson score 6 9 grade 2ductal carcinoma in situ not identifiedlymphovascular invasion not presentperineural invasion presentresected margins:superior margin: free of tumor.inferior margin :free of tumor.medial margin :free of tumor.lateral margin :free of tumor.deep margin :free of tumor.axillary lymph nodes:15 nodes no deposit of tumor.,a) left breast wide excision:maximum dimension tumor 3.5x2.1residual viable tumor presentinvasive ductal carcinoma nuclear grade iilymphovascular invasion not presentall resected margins are free of tumorb) axillary lymph nodes: 15 nodes no deposit of tumorpathological stage: ypt2n0b) left axillary dissection.
MR1804411,right infraclavicular lesion malignant.,a) right infraclavicular lesion.b) right breast lump,a) received 5 grey white linear cores measures 0.5 1cm. entire tissue processed.b)received 4 grey white linear cores measures 0.7 1cm. entire tissue processed.,a) section shows cores of fibro adipose tissue along with skeletal muscle harboring an invasive neoplasm is nested pattern with cells showing eosinophilic to clear cytoplasm pleomorphic nuclei and prominent nucleoli admixed with lymphocytes also seen.b) section shows fibro adipose tissue harboring an invasive neoplasm in cords nest and tubular pattern. the cells show moderate nuclear pleomorphism and increased mitosis. areas of necrosis present. stroma is desmoplastic with dense lymphoplasmacytic infiltrate.,a) right supraclavicular lesion:metastatic carcinomatous depositb) right breast lump:invasive carcinoma nstmodified bloom richardson score is (2+2+3) 7 9.grade 2
MR1804462,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received 4 grey white linear cores measures 0.7 1cm. entire tissue processed.,section shows linear cores of lesion arranged in islands sheets. the cells have markedly pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. interspersed and aggregates of neutrophils lymphocytes and plasma cells seen. stroma shows desmoplasia mitotic figures discerned.,biopsy from left breast:invasive carcinoma nst grade iii.modified bloom richardson score is (3+3+2).8 9
MR1804468,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received 4 grey white linear cores measures 0.7 1cm. entire tissue processed.,section show linear cores of tissue with an infiltrating lesion arranged in islands nest with reaction of stroma . the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows desmoplasia. mitotic figures discerned.,right breast lump core biopsy:invasive carcinoma nst grade ii.modified bloom richardson score is (3+2+1)6 9.
MR1804494,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,section shows linear cores of tissue with an infiltrating lesion arranged in irregular nest islands. the cells have moderately pleomorphic round hyperchromatic nuclei and moderate cytoplasm. stroma shows desmoplasia with scattered inflammatory infiltrate. mitotic figures seen. areas of necrosis seen.,right breast lump core biopsy:invasive carcinoma nst grade iimodified bloom richardson score is (3+2+1)6 9.areas of necrosis seen.
MR1804510,right breast lump carcinoma breast.,biopsy from right breast lump,received 5 grey white linear cores measures 0.7 1cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in tubules and cords. the neoplastic cells round to irregular moderately pleomorphic hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm. mitosis is discerned.,biopsy from right breast lump:invasive ductal carcinoma grade iimodified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1804528,left breast lump possibility of carcinoma breast.,biopsy from left breast,received 4 grey white linear cores measures 0.7x1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrating by neoplastic cells arranged in tubules and cords. the lesional cells have moderately pleomorphic round to irregular nucleus dispersed chromatin prominent nucleoli and moderate cytoplasm. surrounding stroma shows hyalinisation.,biopsy from left breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1804543,carcinoma left breast post partial mastectomy and nact (4cycles).,a) left breast left completion mastectomy with left axillary lymph node dissection(level 1 amp 2)(post nact).b) level 3 nodes.,a) procedure : completion mastectomy post nact post partial mastectomylaterality : left breast.total dimensions :medial lateral :14cm superficial deep : 4cm superior inferior : 19cmskin ellipse : 15x2.5cmnipple : unremarkable.scar surgical defect : linear serous noted measures 15cm in length.tumor bed : shows grey brown fibro tissue measures 2.1 x 1 x 1 cm noted.muscle : absent.adjacent breast : fibrofatty tissue.axillary tail : 10x6.5cm.size of largest node : 1.5x1x0.8representative sections are submitted.b) received fibrofatty tissue measures 4.5x2x0.5cm. entire tissue processed.,section from breast paranchyma show ducts lined by monotonous round cells having round nucleoli diffuse fine chromatin indistinct nucleoli and moderate cytoplasm. these ducts show hyperplasia in a sheets like pattern with central necroses.,a) left breast left completion mastectomy with left axillary lymph node dissection(level 1 amp 2)(post nact):shows ductal carcinoma in situ of solid cribriform and comedo pattern with intermediate nuclear grade. tumor measures 0.5 cm in greatest dimension(microscopically). no definite evidence of residual invasive malignancy is seen. lymphovascular invasion is not identified. perineural invasion is not identified. all resected margins are free of tumor.lymph nodes :nine out of twenty one lymph nodes show metastatic deposits with extranodal extension(9 21). size of the largest tumor deposit measures 5 cm in greatest dimension.b) level 3 nodes:twelve lymph nodes isolated negative for malignancy (0 12).
MR1804568,left breast lump carcinoma breast.,left breast lump core biopsy.,received 3 grey white linear cores measures 0.8 1cm. entire tissue processed.,section shows tumor cell in nests and diffuse sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1804570,right breast lump possibility of carcinoma breast.,biopsy from left breast.,received 3 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by nests and cords of atypical cells having round to oval nuclei and moderate eosinophilic cytoplasm. few cells clusters have clear cytoplasm . stroma shows extensive desmoplasia and lymphoplasmacytic infiltrate. crush artefacts are noted.,biopsy from left breast:invasive ductal carcinoma grade 2modified bloom richardson score is (3+2+2) 7 9.
MR1804573,carcinoma left breast.,a) sentinel lymph nodeb) breast wide excision biopsy.,a) received fibrofatty tissue measures 2.5x2x1.5cm. identified 3 lymph nodes largest measures 1.8x1.4x1cm. cut surface fatty infiltration2nd lymph node measures 0.8x0.5x0.5cm. cut surface grey white3rd lymph node measures 0.8x0.5x0.5cm. cut surface unremarkable.b) wide local excision breast measures 7x7x2.3cm cut surface illdefined lesion with yellow areas measures 1.5x0.8x0.8cm.distance from margins superior margin: 2cminferior margin :2.3cmmedial margin :2.3cmlateral margin :1.8cmdeep :1.5cm,a) sentinel lymph nodes:3 nodes no deposit of tumor.b) breast wide local excision:tumor is composed of pleomorphic cells with hyperchromatic nucleus and scanty cytoplasm. tubular formation (40 )(2) mitotic figures 6 8 10 hpf(2) anaplasia (2)modified bloom richardson score is 6 9lymphovascular invasion not identifiedperineural invasion not identified.resected margin:superior margin: free of tumorinferior margin :free of tumormedial margin :free of tumorlateral margin :free of tumordeep margins :free of tumor,a) sentinel lymph node:3 nodes no deposit of tumor.b) breast wide excision biopsy.:invasive ductal carcinoma grade iimaximum dimension of tumor is 1.5cmlymphovascular invasion not presentperineural invasion not presentall resected margins free of tumor.pathological stage : pt1n0
MR1804576,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 3 grey white linear cores measures 0.7 1cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by cords and small irregular nests of atypical cells having pleomorphic dark irregular nuclei. some with prominent nucleoli and moderate eosinophilic cytoplasm. interspersed lymphocytes and plasma cells noted. stroma shows hyalinisation and dilated blood vessels.,biopsy from left breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is (3+2+2)7 9
MR1804585,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received multiple fragmented grey white linear cores measures 0.2 0.5cm. entire tissue processed.,section shows fragmented tissue with neoplastic lesion arranged in sheets having markedly pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. few nest of cells having round nuclei and abundant amount of pale eosinophilic to clear cytoplasm. few signet ring cells are also seen. stroma shows sclerosis and myxoid change with a cellular eosinophilic material noted. multinucleated tumor giant cells seen.,biopsy from right breast:poorly differentiated malignancy high grade carcinoma metaplastic carcinoma
MR1804604,biopsy from right breast mass.,right breast mass biopsy.,received 4 grey white linear cores measures 1 to 1.2cm.,section shows cores of fibroadipose tissue harboring an infiltrate neoplasm in cords nest and tubules. the neoplastic cells show moderate nuclear pleomorphism eosinophilic to clear cytoplasm and increased mitosis. stroma is desmoplastic.,biopsy from right breast. :invasive carcinoma nst.grade iimodified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1804655,left breast lump possibility of carcinoma breast.,left breast lump.,received 4 grey white linear cores measures 1 to 1.2 cm entire tissue processed.,sections shows linear cores of breast parenchyma infiltrate by neoplastic cells arranged in tubules and cords. the tumor cells have moderately pleomorphic round hyperchromatic nucleus with moderate cytoplasm. mitosis is discerned.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1804673,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received 5 grey white lineal cores measures 0.8 to 1 cm. entire tissue processed.,section shows tumor cells is nest and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6 (3+2+1).
MR1804697,right breast lump possibility of carcinoma breast.,right breast lump biopsy,received 4 grey white linear cores measures 1 1.2cm . entire tissue processed.,section shows cores of breast tissue with scattered compressed ducts with preserved epithelial and myoepithelial layers. surrounded by abundant stroma with bland fibroblast and collagen. no evidence of invasion or invasive carcinoma in the section examined,right breast lump biopsy:benign breast lesion.suggestive of fibroadenoma.
MR1804711,right breast lump possibility of carcinoma breast.,right breast lump biopsy.,received 4 grey white lineal cores measures 0.8 to 1 cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in cells and tubules. the lesional cells are round to oval having hyperchromatic nuclei and scant cytoplasm. the cells exhibit moderate nuclear pleomorphism. stroma shows desmoplasia. mitoses are 5 6 10 hpf.,right breast lump biopsy.invasive ductal carcinoma grade ii.mbr score 7 9
MR1804741,right breast lump possibility of carcinoma breast.,right breast lump.,received 4 grey white linear cores measures 0.7 to 1 cm entire tissue processed.,sections shows linear cores of tissue with irregular islands infiltrating into stroma. the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows extensive desmoplasia. dilated blood vessels seen.,right breast lump core biopsy :invasive carcinoma nst grade 2.mbr score : (3+2+1) 6 9
MR1804771,case of left breast carcinoma,a) wide local excisionb) left axillary lymph nodes,a) received lumpectomy specimen measures 10x9x5cm skin ellipse measures 6.5x4cm cut surface shows a grey white lesion measures 3.5x3x2cm.entire tissue processed.distance from marginssuperior margin: 1.5cminferior margin : 2cmmedial margin : .5cmlateral margin : 1cmdeep margin : 2cmb) received fibrofatty tissue measures 9x8x4cm largest lymph node measures 2x2x1cm cut surface grey white.,a) tumor is composed of ducts clumps groups and cells with pleomorphic hyperchromatic nucleus and scant cytoplasm. tubular formation less than 10 (3) mitotic figures (1) nuclear pleomorphism(2).modified bloom richardson score is 6 9 grade iiductal carcinoma in situ not present.lymphovascular invasion not present.perineural invasion present.resected margins:superior margin: free of tumor.inferior margin :free of tumor.medial margin :free of tumor.lateral margin :free of tumor.deep margin :free of tumor.axillary lymph nodes:15 nodes no deposits of tumor.,a) left breast wide local excision:wide local excision invasive ductal carcinoma grade iimaximum dimension of tumor 3.5x3x2cmlymphovascular invasion not present.all resected margins are free of tumor.b) left axillary lymph nodes:15 nodes . no deposit of tumor.
MR1804786,right breast lump core biopsy.,right breast lump core biopsy.,received 3 grey white linear cores measures 0.5 to 0.8cm. entire tissue processed.,section show linear cores of tissue with infiltrating lesion arranged islands nest and sheets. the cells have round hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows desmoplasia. mitotic figures seen.,right breast lump core biopsy :invasive carcinoma nst grade iimodified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1804795,carcinoma left breast.,a) wide excision left breast.b) left axillary sentinel node.c) left axillary lymph nodes.,a) received wide local excision specimen measures 6.5x5x2.6cmcut surface a grey white firm lesion measures 1.8x1x1cmdistance from margins12 0 clock :1cm6 0 clock :2cm3 0 clock :2cm9 0 clock :3cmdeep margin : 0.5cmb) received fibrofatty tissue measures 3x2x2 cm identified 4 lymph nodes largest lymph nodes measures 1.4x1x1cm cut surface grey white.c) received multiple fibrofatty tissue measures 6x4.5x2cm.largest lymph nodes measures 1.5x1x1cm cut surface grey whitedissected 12 nodes.,tumor is composed of pleomorphic cells with hyperchromatic and scanty cytoplasm. surrounding the tumor dense lymphoplasmacytic infiltration is present.tubule formation 3 anaplasia 2 mitotic figures 1modified bloom richardson score is 6 9 nuclear grade iilymphovascular invasion presentperineural invasion not identifiedresected margins superior margin: free of tumorinferior margin : free of tumormedial margin : free of tumorlateral margin : free of tumordeep margins : free of tumorb) sentinel lymph node:2 nodes show metastatic deposit of tumor are out of 4 nodes perinodal spread present.c) axilary lymph node:one node shows metastatic deposit of tumor out of 12 nodes,a) wide excision left breast:invasive ductal carcinoma grade ii.maximum dimension of tumor is 1.8 cmlymphovascular invasion presentperineural invasion is not identifiedductal carcinoma not identified.all resected margins are free of tumorb) left axillary sentinel node:2 nodes show deposit of tumor out of 4 nodes.c) left axillary lymph nodes:one node shows metastatic deposit of tumor out of 12 nodes total no of positive nodes 3 nodes out of 16 nodes perinodal spread present.pathological stage : pt1no
MR1804812,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,linear cores of breast parenchyma harboring a neoplasm arranged in cords and tubules. the neoplastic cells have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is elastotic.,biopsy from left breast lump:invasive carcinoma nst grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1804815,left breast lump.,left breast lump biopsy.,received 5 grey white liner color measures 0.5 to 1 cm. entire tissue processed.,section from breast paranchyma showing infitrative lesion. the cells are round to oval with abundant eosinophilic cytoplasm and pleomorphic nuclei with inconspicuous nucleoli. adjacent stroma showing fibrosis. no areas of necrosis seen.,left breast lump core biopsy.invasive ductal carcinoma grade 2. modified bloom richardson score 6 (3+2+1).
MR1804824,left breast lump possibility of carcinoma breast.,left breast lump.,received 3 grey white linear cores measures 1 to 1.2 cm entire tissue processed.,sections shows linear cores of breast parenchyma showing extensive sclerosis and periductal inflammatory infiltrates consisting of histiocytes lymphocytes plasma cells and eosinophils. stroma shows hyalinised blood vessels. focal areas of necrosis seen. no definite granulomas are seen.,left breast lump biopsy :feature suggestive of chronic non specific mastitis.no evidence of malignancy or granulomas is seen.
MR1804844,left breast lesion carcinoma.,left breast core biopsy.,received 4 grey white linear cores measures 0.8 to 1 cm,section shows cores of tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7 (3+2+2).
MR1804845,residual carcinoma right breast post nact post lumpectomy.,a)right breast conservative surgeryb)right axillary lymphatics.,a) received lumpectomy measures 9x9x4.5cm. cut surface grey yellow central necrosis measures 1.5x1.2x1cm. distance from margins :superior margin : 1.5cm.inferior margin : 2 cm.medial margin : 3.2 cm.lateral margin : 4 cm.deep margin : 1.5 cm.b) received fibrofattty tissue measures 7x5x1.5cm. largest lymphnodes measures 2x1x1cm.,a) section studied shows breast parenchyma with areas of hyalinisation and fibrosis.also seen are dense lymphomononuclear cells with interspersed histiocytes and congested blood vessels. cytomegaly multi nucleation and intracytoplastic inclusions are noted. no evidence of atypia or malignancy noted.,a) right breast conservative surgery. no residual viable tumor seen. chemotherapy related changes noted. all margins of resection are free of tumor.b) right axillary lymph nodes dissection. isolated eleven lymphnodes are free of tumor. (0 11)
MR1804851,right breast lump possibility of carcinoma breast.,right breast lump.,received 4 grey white linear cores measures 0.8 to 1 cm entire tissue processed.,sections shows linear cores of tissue with an infiltrating lesion arranged in small nest islands and sheets. the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount amount of cytoplasm. stroma shows desmoplastic mitotic figures seen.,right breast lump core biopsy :invasive carcinoma nst grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1804880,left breast lump possibility of carcinoma breast..,biopsy from left breast.,received multiple grey white linear cores measures 1 1.2cm. entire tissue processed.,section shows linear tissue cores harboring an infiltrative neoplasm arranged in cords and nests of neoplastic cells exhibiting increased n c ratio pleomorphic hypechromatic nuclei prominent nucleoli and moderate to scanty pale eosinophilic cytoplasm. the intervening stroma shows presence of desmoplasia.,biopsy from left breast:invasive carcinoma breast nst grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1804895,right breast lesion birads 4,biopsy form right breast lesion.,received six grey white linear cores measures 0.2 to 0.6 cm.entire tissues processed.,section shows multiple cores of breast parenchyma with dilated ducts showing atypical cells.the cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. all the ducts are lined by myoepthelial cells peripherally. stroma is hyalinized. mitosis discerned.,right breast lesion biopsy :shows ductal carcinoma in situ of cribriform type with intermediate nuclear grade.no definite evidence of invasive malignancy is seen.suggest further confirmation for invasive component on larger specimen.
MR1804915,right axillary mass possibility of neoplastic etiology.,right axillary mass of breast biopsy,received 4 grey white linear cores measures 0.7 1cm . entire tissue processed.,sections shows linear cores of breast parenchyma composed of invasive nests and sheets of dysplastic cells showing moderate anisonucleosis and hyperchromatic nuclei with prominent nucleoli. the intervening stroma is desmoplastic and shows scanty inflammatory infiltrate.,right axillary mass of breast biopsy:invasive carcinoma of ductal origin nstmodified bloom richardson score is 2+2+2 6 9 grade ii.
MR1804916,right breast lump possibility of carcinoma breast.,right breast biopsy,received 3 grey white linear cores measures 0.8 1.0cm . entire tissue processed.,section shows linear cores of breast parenchyma composed of invasive nest and sheets of dysplastic ductal cells showing moderate pleomorphism and hyperchromatic nuclei. the intervening stroma is desmoplastic.,right breast biopsy:invasive carcinoma of ductal origin nst modified bloom richardson score is 2+2+2 6 9.
MR1804954,carcinoma breast post rt.left adrenal mass metastatic.,left adrenal lesion core biopsy.,received 4 grey white to linear cores measures 1 1.3cm. entire tissue processed.,section shows cores of tissue infiltrates by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left adrenal lesion core biopsy:positive for malignancy.possibly metastasis.suggest further workup.
MR1804982,left breast mass,left breast mass core biopsy.,received 5 grey white linear cores measures 0.6to 1.2cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets nests and tubules. individual tumor cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1804985,carcinoma right breast,right breast mass biopsy,received 4 grey white linear cores measures 0.8 1cm . entire tissue processed.,section shows multiple fragments of infiltrating neoplasm arranged in nests and sheets. the cells having the lesion are round to oval hyperchromatic nuclei with scant to moderate cytoplasm. atypical mitotic figures are seen. area of necrosis and hemorrhage seen.,right breast mass biopsy:invasive carcinoma with papillary features. nuclear grade ii
MR1805019,carcinoma right breast.,biopsy from right breast mass.,received 5 grey white to grey yellow linear cores measures 0.3 1.4cm. entire tissue processed.,section shows multiple infiltrating neoplasm arranged in sheets and nests. the cells forming the lesions are round to oval nuclei scant to moderate cytoplasm. inflammatory infiltrate composed of lymphoplasmacytes. few mitotic figures seen. areas of hyalinisation seen.,biopsy from right breast mass:nfiltrating ductal carcinoma grade 2modified bloom richardson score is (3+2+2)7 9
MR1805029,left breast mass phylloides carcinoma,left breast mass core biopsy.,received 5 grey white to grey yellow linear cores measures 1 1.4cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets. individual tumor cells are in spindle shape with elongated pleomorphic hyperchromatic nuclei and moderate amount of cytoplasm. few cells with bizzre nuclei and few with multinucleated giant cells are seen. mitosis is discerned.,left breast mass core biopsy:suggestive of spindle cell neoplasm. phylloides tumor sarcomaneeds further confirmation on larger specimen with ihc.
MR1805039,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measures 1 1.4cm. entire tissue processed.,section shows multiple cores of breast tissue with ducts showing solid type ductal carcinoma in situ. there is periductal focal inflammatory infiltrate. no evidence of invasive carcinoma in the section examined,biopsy from right breast:ductal carcinoma in situ solid type (intermediate grade).
MR1805098,carcinoma left breast,biopsy from ulcerated lesion in left breast,skin covered soft tissue bits measures 1.3x0.9x0.6cmskin surface shows discolouration,section shows a tissue lined by squamous epithelium harbours an invasive neoplasm arranged in sheets and nests and tubules. the lesional cells are large having round to irregular nucleus with coarse chromatin prominent nucleoli and moderate eosinophilic cytoplasm.,biopsy from ulcerated lesion in left breast:features are suggestive of invasive carcinoma ( nst) grade ii.modified bloom richardson score is7 9 ( 3+2+2).
MR1805102,carcinoma left breast post nact.,left modified radical mastectomy post nact.,received in : formalinprocedure : modified radical mastectomy laterality : lefttotal dimensions :medial to lateral :17cm superficial to deep :6cm superior to inferior:13cmskin ellipse : 13x8cmnipple : edematous tumor :singletumor size :1.5x1x1cm scar surgical defect :5cm location of tumor : 12 0 clock positionmargin of tumor : ill defineddeep margin : 2.5cmmuscle : 8x8cmadjacent breast : fibrofatty tissueaxillary tail :13x6x2cmsize of largest node :1.5x1x0.5cm cut surface grey white grey brown,show residual viable tumor with few foci of invasive carcinoma with extensive ductal carcinoma in situ solid and comedo type high grade.,left modified radical mastectomy:histological type: invasive ductal carcinoma nst.grade:2tumor measures maximum dimension1.5 cminvasive component measures 0.5 cmductal carcinoma in situ measures 1cmmodified br score is6 9tubule formation: 2 nuclear pleomorphism:2 mitotic figures: 2ductal carcinoma in situ is extensive solid and comedo type high grade.lymphovascular invasion is presentperineural invasion is not identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: 8 lymph nodes metastasis:1(1 8)largest tumor deposit measures 0.5cm.no extranodal extension.pathological stage: ypt1n1. summary: invasive ductal carcinoma left modified radical mastectomy post nacttumor grade: 2.lymphnode status: 1 out of 8 nodes show viable metastatic deposit tumor measures 0.5cm.no extranodal extension.
MR1805117,case of left breast.,a) hot nodeb) blue +hot node.c) non blue non hot node.d)left breast wide excision.e) revised deep margin.,a) received single lymph node measures 0.6x0.5x0.5cm. entire tissue processed.b) received fibrofatty tissue measures 1.5x0.8x0.6cm. entire tissue processed.identified 1 lymph nodecut surface fatty infiltrate.c) received fibrofatty tissue measures 1x0.6x0.5cmentire tissue processed.identified 1 lymph node measures 0.4x0.4x0.3cm. entire tissue processed.d) received lumpectomy specimen measures 4.5x3.5x2.3cm.cut surface ill defined grey white lesion.skin ellipse 2x1.5cm.distance from marginssuperior margin: 1.5cminferior margin : 1cmmedial margin : 1.5cmlateral margin : 0.5cmdeep margin : 0.5cme)fibrofatty tissue measures 1.5x1.2x0.8cm. one surface stiched noted. stiched surface inked.,sentinel lymph nodes: 4 nodes. no deposit of tumor.wide excision:the section shows defuse ducts of tumor cells arranged in a linear single line pattern. the cells show pleomorphic hyperchromatic nucleus with scanty cytoplasm.tubule formation 3mitotic figures 2anaplasia 2modified bloom richardson score is 7 9 grade ii.lymphovascular invasion not present.perineural invasion not presentresected margins :superior margin: free of tumor.inferior margin :free of tumor.medial margin :free of tumor.lateral margin :free of tumor.deep margin adenosis :free of tumor.resected deep margin free of tumor.,wide local excision:maximum dimension tumor is 1.8cminvasive carcinoma with lobular featuresductal carcinoma in situ not identified.perineural invasion not identifiedlymphovascular invasion not present.all resected margins are free of tumor.resected deep margins free of tumorsentinel lymph node 4 nodes. no deposit of tumor.pathological stage: pt1n0
MR1805138,right breast possibility of carcinoma breast.,biopsy from right breast.,received 3 grey white to grey brown linear cores measures 0.8 1cm. entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged in glandular pattern and an clusters . the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous and moderate cytoplasm. the intervening stroma is elastotic.,biopsy from right breast:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation 3nuclear pleomorphism: 2mitotic figures : 2 7 9
MR1805150,left breast lump possibility of carcinoma breast.,left breast lump biopsy.,received 5 gray white linear cores measures 0.3 to 0.6 cm.entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in tubules and cords.the lesion cells are round to oval having hyperchromatic nucleus and moderate cytoplasm. stroma shows desmoplasia. mitosis 5 6 hpf,left breast lump biopsy.invasive ductal carcinoma grade 2. modified bloom richardson sore 6(2+2+2).
MR1805175,left breast lump birads v,biopsy from left breast lump.,received 4 grey white linear cores measures 0.4 0.6cm. entire tissue processed.,section from the breast parenchyma shows a infiltration lesion arranged in sheets nests and areas of necrosis. the cells are round to oval hyperchromatic nuclei. scant to moderate cytoplasm. mild pleomorphic nuclei seen. atypical mitotic figures are seen. areas of necrosis seen.,biopsy from left breast lump:infiltrating ductal carcinoma grade 2.modified bloom richardson score is 7 9(3+2+2).areas of necrosis seen.
MR1805182,left breast lump possibility of carcinoma breast,biopsy from left breast lump,received 4 grey white linear cores measures 1 to 1.3cm. entire tissue processed.,linear cores of breast parenchyma harboring a neoplasm arranged as islands and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm .areas of necrosis seen.,biopsy from left breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1805192,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received 5 grey white linear cores measures 0.2 0.5cm. entire tissue processed.,section shows linear cores of breast parenchyma with are focus shows atypical cells having round to oval pleomorphic nucleus inconspicuous nucleoli and moderate cytoplasm. extensive hyalinisation noted.,biopsy from right breast:solitary focus of atypical cells with crush artifactspossibility of malignancy needs to be ruled out on a repeat biopsy.
MR1805193,right breast lump.,right modified radical mastectomy post nact.,received in : 10 nbf.procedure : right modified radical mastectomy post nact.laterality : right.total dimensions : medial to lateral 10cm. superficial to deep 4cm. superior to inferior 10cm.skin ellipse : 8x6cm. nipple : retracted.scar surgical defect : absent.tumor : single.location of tumor : 2.4x2.4x2cm.margins of tumor : illdefined. deep margin : 1cm.muscle : 1x0.6cm.axillary tail : 4x4x3cm.,sections show breast parenchyma harboring a lesion with cells in sheets cords trabeculae and nests. the cells have scant to moderate cytoplasm with some having abundant clear cytoplasm round to oval pleomorphic hyperchromatic nuclei with some having prominent nucleoli. atypical mitosis discerned (1 2 hpf). numerous sclerosed blood vessels seen interspersed throughout the tumor. surrounding stroma is desmoplastic.,right modified radical mastectomy post nact.tumor bed: 2.4x2.4x2cm.histological type: residual viable invasive ductal carcinoma.grade: iiitumor measures maximum dimension 2.4cminvasive component measures 2.4cmmodified br score is 8 9tubule formation: 3nuclear pleomorphism: 2mitotic figures: 3ductal carcinoma in situ is absent.lymphovascular invasion is absent.perineural invasion is absent.posterior resection margin is free of tumor.nipple and areola is free of tumor.lymph nodes: 15 lymph nodes metastasis: 0 (0 15).no metastatic deposit of tumor out of 15 nodes. pathological stage: ypt2n0summary:residual viable invasive ductal carcinoma right breast.tumor grade: iiilymphnode status:0 15
MR1805202,left thigh mass possibility of deposit,a) left thigh mass b) retroperitoneal node,a) received multiple grey white linear cores measures 1.2x1.5cm. entire tissue processed.b) received multiple grey brown linear cores measures 0.2 0.6cm. entire tissue processed.,a amp b) section from the thigh mass and lymph node show similar morphology. linear cores of tissue show closely packed tubules and micropapillary structures lined by dysplastic columnar cells that exhibit hyperchromatic nuclei moderate nuclear pleomorphism and mitotic activity. stroma is fibrotic biopsy of node shows near total replacement by tumor,a) left thigh mass amp b) retroperitoneal node:metastatic adenocarcinoma serous carcinoma from ovary adenocarcinoma from lung breast git.suggest ihc and clinical correlation
MR1805207,right breast lump possibility of carcinoma breast,biopsy from right breast,received 5 grey white linear cores measures 0.5 1.2cm. entire tissue processed.,sections shows invasive sheets and nests of dysplastic ductal cells showing moderate anisonucleosis hyperchromatic nuclei seen invading the fibrous stroma mild mononuclear infiltrates are seen.,biopsy from right breast:invasive carcinoma of ductal origin nst grade ii.modified bloom richardson score is 2+2+2 6 9.
MR1805210,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received 4 grey white linear cores measures 0.3 0.8cm. entire tissue processed,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in cords. the tumor cells have moderately p leomorphic nucleus inconspicuous nucleoli and moderate cytoplasm. mitosis is discerned.,biopsy from left breast:invasive ductal carcinoma (nst) grade ii.modified bloom richardson score is 3+2+2 7 9.
MR1805212,left breast lump possibility of carcinoma breast.,biopsy from left breast.,received 3 grey white to linear cores measures 0.6 1cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in cords and sheets. the lesional cells are large with round nucleus dispersed chromatin and moderate cytoplasm. mitosis is discerned.,biopsy from left breast:invasive carcinoma ( nst) grade 2modified bloom richardson score is 3+2+2 7 9
MR1805234,right breast lump possibility of carcinoma breast.,biopsy from right breast,received 4 grey white to grey yellow linear cores measures 0.8 1.2cm. entire tissue processed.,section shows linear cores of fibrofatty infiltrated by neoplastic cells arranged in cords . the neoplastic cells have moderately pleomorphic round hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm.,biopsy from right breast:invasive carcinoma ( nst) nuclear grade ii
MR1805239,known case of carcinoma breast.,biopsy from liver lesion,received 5 grey white to grey brown linear cores measures 0.5 0.8cm. entire tissue processed.,section shows linear cores of liver parenchyma infiltrating by neoplastic cells arranged in tubules and glandular pattern. the lesional cells have moderately pleomorphic round to oval hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm. areas of necrosis and myxoid changes noted.,biopsy from liver lesion:metastatic adenocarcinoma in a known case of carcinoma breast.
MR1805314,carcinoma left breast.,a) breast conservative surgery.b) left axillary lymphatics.,a) breast conservative surgery.received lumpectomy specimen measures 5.5x4x3cm. cutsurface small grey brown area with calcification measures 0.8x0.5x0.5cm. skin ellipse measures 3.5x1cm. distance from margins : superior margin : 1cm.inferior margin : 1.5 cm.medial margin : 2 cm.lateral margin : 2 cm. deep margin : 1.2cm.b) received fibrofatty tissue measures 7x6x2cm. largest lymphnode measures 1.2x1x1cm. cutsurface grey white.,the section show atypical epithelial hyperplasia adenosis and fibrocytic dilated ducts with apocrine metaplasia. there is no evidence of residual viable invasive carcinoma or ductal carcinoma in situ present. resected margin. : superior inferior medial lateral and deep margin. inked margin are free of tumor. b) left axillary lymphocytes :11 nodes no deposits of tumor.,breast conservative surgery :no residual viable tumor.all resected margins are free from the tumor. lymphnodes : 11 nodes no deposits of tumor(0 11).
MR1805372,left breast lump metastatic carcinoma breast,left breast lump core biopsy.,received 7 grey white to grey yellow linear cores measures 0.3 to 1cm. entire tissue processed.,section shows cores of breast tissue infiltrated by breast tissue by tumor cells in cords and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1805376,left breast lump possibility of carcinoma breast.,left breast lump biopsy.,received five grey white to grey brown linear cores measures 0.6 1cm. entire tissue processed.,section shows multiple cores with infiltrating lesion arranged in nests tubules and cords. the lesion cells are round to oval with hyperchromatic nuclei and have moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1805418,left breast lump carcinoma breast.,biopsy from left breast.,received 5 grey white linear cores measures 1 1.2cm. entire tissue processed.,section shows multiple linear cores the breast parenchyma shows infiltrating neoplasm arranged in acini and nests. the cells foaming. the lesion are round to oval nucleus with scant cytoplasm hyperchromatic nuclei in the background desmoplastic stroma. few mitotic figures are identified.,biopsy from left breast:invasive ductal carcinoma grade 2modified bloom richardson score is (2+2+1)5 9
MR1805432,known case of carcinoma left breast.,left breast core biopsy.,received 4 grey white linear core measures 0.5 cm. entire tissue processed.,section shows few ductules lined by atypical cells with hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy. (post chemo) :few ductules are seen with moderate to marked atypia.suggest excision of the lump for further confirmation.
MR1805442,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 5 grey white to grey brown linear cores measures 0.8 1.2cm. entire tissue processed,section shows linear cores of breast parenchyma infiltrating by neoplastic cells arranged in cords and tubules. the lesional cells have round hyperchromatic nucleus few with inconspicuous nucleoli and moderate cytoplasm.,biopsy from left breast lump:invasive ductal carcinoma grade iimodified bloom richardson score is 6 9(2+2+2).
MR1805458,case of right breast lump.,a) right sentinel lymph node (blue node).b) right sentinel lymph node (non blue non hot node).c) right sentinel lymph node (intramammary node).d) right breast right breast conservative surgery.e) right breast right mastectomy(post bcs).,hot nodes:a) received fibrofatty tissue measures 2x1x0.8 cm. largest lymph node measures 0.7x0.5x0.5 cm cut surface shows unremarkable.non blue non hot nodes:b) received fibrofatty tissue measures 3.5x2.5x1.5 cm. 2 lymph nodes identified largest lymph node measures 1.5x0.8x0.6 cm cut surface shows unremarkable.c) received 2 fibrofatty tissue bits larger measures 2.5x2x0.8 cm. smaller measures 0.6x0.4 cm.yields 2 nodes. largest measures 1.5 cm in greatest dimension.d) received lumpectomy specimen measures 6.5x6x4 cm. cut surface shows grey white firm lesion measures 3x2.7x2.8 cm. distance from margins :superior margin : 1.5 cminferior margin : 1.7 cmmedial margin : 1.7 cmlateral margin : 1.7 cmdeep margin : 1.3 cme) received in : formalinprocedure : mastectomylaterality : righttotal dimensions : medial lateral : 17 cm superficial deep : 5 cm superior inferior : 23 cmskin ellipse : 17x11 cm upper central areas shows surgical defects measures 6 cm.tumor bed measures 8x6 cm grossly no tumor.deep margin : 1 cmmuscle : absentadjacent breast : fibrofatty axillary tail : absent,section shows breast parenchyma harboring infiltrating lesion arranged in tubules and cords. the lesional cells are round to oval having hyperchromatic nuclei prominent nucleoli in few and moderate cytoplasm. the cells exhibit moderate neoplasm. stroma is desmoplastic and showing lymphoplasmacytic infiltrate. mitoses 6 8 10 hpf. extensive areas of dcis comedo type noted. section from mastectomy shows breast parenchyma with no residual tumor. usual ductal hyperplasia noted.,a) right sentinel lymph node (hot nodes): identified three lymph nodes are free of tumor (0 3).b) right sentinel lymph node (non blue non hot node): identified two lymph nodes are free of tumor (0 2).c) right sentinel lymph node (intramammary node): no lymph nodes identified shows breast parenchyma with atypical ductal hyperplasia. d) right breast right breast conservative surgery :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(2+2+2). tumor measures 3 cm in greatest dimension. ductal carcinoma in situ present comedo type intermediate nuclear grade. lymphovascular invasion is not identified. perineural invasion is not identified. inferior margin show usual ductal hyperplasia. medial margin shows atypical ductal hyperplasia. rest all margins including deep margin are free of tumor.e) right breast right mastectomy(post bcs): no residual tumor is seen. posterior resection margin is free of tumor. nipple and aerola are unremarkable.
MR1805465,right breast lump possibility of carcinoma breast.,right breast lump biopsy,received 5 grey white linear cores measures 1 1.2cm. entire tissue processed.,section shows breast parenchyma harboring infiltrating lesion arranged in nests cords and vague tubules. the lesion cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. stroma shows hyalinisation.,right breast lump biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1805466,left breast lump carcinoma breast.,biopsy from left breast lump,received 5 grey white to grey brown linear cores measures 1.0 to 1.2cm. entire tissue processed.,linear cores breast parenchyma harboring a neoplasm arranged in clusters and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is elastotic.,biopsy from left breast lump:infiltrating ductal carcinoma grade 2modified bloom richardson score is 7 9 .tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1805478,left breast lump possibility of carcinoma breast.,trucut left breast.,received 3 grey white linear cores measures 0.8 to 1 cm. entire tissue processed.,trucut left breast :section shows breast parenchyma with invasive sheets of nests of dysplastic ductal cells showing moderate pleomorphism hyperchromatic nuclei. the intervening stroma is desmoplastic.,trucut biopsy left breast:invasive carcinoma of ductal origin nst grade ii.mbr score (2+2+3 7 9)
MR1805482,carcinoma left breast.,a)left breast wide excision.b) sentinel lymph node.,received lumpectomy specimen measures 7.2x5.2x2cmskin flap measures 6.5x2.9cm.cut surface shows grey white firm lesion measures 2.2x2x1cmdistance from marginssuperior margin: 1.9cm.inferior margin : 1.4cm.medial margin : 3cm.lateral margin : 3cm.deep margin : 0.4cm.b) received fibrofatty tissue measures 2x2x1cm. identified 5 lymph nodes.largest measures 0.7x0.5x0.5cm.,a) wide lumpectomy.tumor is composed of pleomorphic cells with hyperchromatic and scanty cytoplasm. tumor formation is less than 10 (3)mitotic figures are 8 10 hpf (2)anaplasia (2)modified bloom richardson score is 7 9 grade ii.ductal carcinoma in situ not present.perineural invasion not present.lymphovascular invasion not present.resected margins:superior margin: free of tumorinferior margin : free of tumormedial margin : free of tumorlateral margin : free of tumordeep margin : free of tumorsentinel lymph node: 5 nodes no deposit of tumor.,a)left breast wide excision:invasive ductal carcinoma maximum dimension tumor measures 2.2x2x1cm. grade iilymphovascular invaison no present.ductal carcinoma in situ not present.all resected margins are free of tumor.sentinel lymph node 5 nodes . no deposit of tumor.b) sentinel lymph node.
MR1805529,left breast lump carcinoma breast.,biopsy from left breast lump.,received 6 grey white linear cores measures 0.5 1cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring a cellular infiltrating lesion arranged in sheets and nests. the cells are ovoid having moderate amount of cytoplasm pleomorphic hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned.,biopsy from left breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1805575,left breast lump possibility of carcinoma breast.,left breast lump core biopsy.,received 5 grey white to grey brown linear cores measures 0.8 1.2cm. entire tissue processed.,sections shows cores of tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1805595,left breast lump possibility of carcinoma breast.,left breast lump biopsy.,received five grey white to grey brown linear cores measures 0.2 0.3cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in nests cords and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular invasion is identified.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). lymphovascular invasion is seen. ductal carcinoma in situ of cribriform pattern with intermediate nuclear grade is seen.
MR1805606,left breast lump possibility of carcinoma breast.,left breast lump biopsy.,received 4 grey white to grey yellow linear cores measures 1 1.2cm. entire tissue processed.,section shows breast parenchyma harboring infiltrating lesion arranged in nests tubules and cords. the lesional cells are round to oval having moderately pleomorphic hyperchromatic nuclei and moderate cytoplasm. stroma shows desmoplasia.,left breast lump biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1805613,complaint of lump in the right breast for the past 2 months.,a) sentinel lymph nodeb) wide local excisionc) revised inferior marginsd) re excised deep margin tagged outer.,a) received fibrofatty tissue measures 3x2x1cm. entire tissue processedisolated 3 lymph nodeslargest measures 1.5x1x0.6cm. cut surface infiltrating.b) received wide local excision right breast measures 5x3.5x3cm cut surface grey white ill defined lesion measures 2.2x1.4x1.4cmdistance from margins:superior margin :2cminferior margins :1cmmedial margin :0.3cmlateral margin :2cmdeep margin : 0.3c) received fibrofatty tissue measures 2.5x1.5x0.6cm are surfaced inked other surface striched.d) received fibrofatty tissue measures 3x2.5x1cm. one surface is threaded.,a) sentinel lymph node: 3 nodes no deposit of tumor.b) wide local excision :the section sows sheets of pleomorphic cells with vesicular nucleus and prominent nuclei and syncitial cytoplasm. intratumoral and peritumor lymphocytic infiltration in presenttubular formation 3mitotic figures 3anaplasia 2modified bloom richardson score 8 9 grade iiiductal carcinoma in situ not presentlymphovascular invasion not presentperineural invasion not presentresected margins:superior margin : free of tumorinferior margins : shows epithelial hyperplasia free of tumormedial margin : free of tumorlateral margin : free of tumordeep margin : free of tumorc) revised inferior margins is free of tumord) re excised deep margin is free of tumor,wide local excision:invasive carcinoma with medullary carcinoma like features grade iiilymphovascular invasion not presentall resected margins are free from tumor.sentinel lymph nodes 3 nodes. no deposit of tumor.pathological stage : pt2n0
MR1805619,left breast carcinoma.,a) left breast breast conservative surgery.b) left sentinel lymph nodes.,a) received lumpectomy specimen measures 11x7x3.5 cmon serial section identified a grey white illdefined lesion measures 1.5x1x0.8 cm (tumor 1) another satellite lesion measures 0.8 x 0.6 x 0.5 cm is noted 0.4 cm away from the tumor 1.distance from different margins:superior margin : 2.5 cminferior margin : 2 cmmedial margin : 2 cmlateral margin : 2.5 cmdeep margin : 2 cmb) received multiple fibrofatty tissue bits altogether measures 2.5x1.8x1 cm. largest measures 1.8x0.8x0.8 cm entire tissue processed.,section shows breast parenchyma harboring infiltrating lesion arranged in tubules and cords. the lesional cells are round to oval having vesicular nuclei prominent nucleoli and moderate cytoplasm. cells exhibit moderate neoplasm. stroma shows desmoplasia. mitoses 2 3 10hpf. areas of dcis (cribriform and solid type) noted.,a) left breast breast conservative surgery :invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1). tumor measures 1.5 cm in greatest dimension. lymphovascular invasion is not indeterminate. perineural invasion is identified. ductal carcinoma in situ of cribriform and solid pattern with intermediate nuclear grade. all resected margins are free of tumor. overlying skin is free of tumor.lymph nodes : identified one intramammary lymph node show tumor deposit measuring 0.7 cm in greatest dimension (1 1). no perinodal spread is seen.b) left sentinel lymph nodes : one out of seven lymph nodes identified show tumor deposit measuring 0.2 cm in greatest dimension (1 7). no perinodal spread is seen.
MR1805656,right breast lump carcinoma breast.,right breast lump biopsy.,received 4 grey white to grey yellow linear cores measures 1 1.2cm. entire tissue processed.,section shows tumor cells in tubules and cords. the lesional cells are round to oval having hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump biopsy:invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1805706,left breast lump (12 0 clock ) possibility of carcinoma breast.,left breast core biopsy.,received 6 grey white to grey yellow linear cores measures 0.2 0.4cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells lying in sheets and nests in pools of extracelluar mucin. individual tumor cells have abundant mucinous to clear cytoplasm and hyperchromatic eccentrically placed nuclei.,left breast core biopsy:invasive carcinoma with many signet ring cells.
MR1805715,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received 3 grey white linear cores measures 0.6 1cm. entire tissue processed.,section shows invasive sheets of dysplastic ductal cells showing moderate pleomorphism hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. mitotic activity is discerned. the intervening stroma is desmoplastic. areas of necrosis seen.,biopsy from right breast:invasive carcinoma of ductal origin nst grade iimodified bloom richardson score is 6 9(2+2+2).
MR1805734,right breast lump possibility of carcinoma breast.,biopsy from right breast,received 3 grey white linear cores measures 0.5 0.8cm. entire tissue processed.,section shows invasive sheets and nests of round to oval cells arranged as dyscohesive ductal cells showing mild pleomorphism and hyperchromatic nuclei. the intervening stroma is desmoplastic.,biopsy from right breast:invasive ductal carcinoma nos grade imodified bloom richardson score is 5 9.(2+2+1)
MR1805737,right breast lump possibility of carcinoma breast.,biopsy from right breast.,received 3 grey white linear cores measures 0.5 0.8cm. entire tissue processed.,section show breast parenchyma with invasive sheets and nests of dysplastic ductal cells showing moderate pleomorphism hyperchromatic nuclei and prominent nucleoli. the intervening stroma is desmoplastic.,biopsy from right breast:invasive carcinoma of ductal origin nst grade 2.modified bloom richardson score is (2+2+2) 6 9.
MR1805756,left breast lump carcinoma breast.,biopsy from left breast lump.,received 5 grey white to grey yellow linear cores measures 0.5 1cm. entire tissue processed.,linear cores of breast parenchyma harboring a neoplasm arranged as sheets and clusters. the neoplastic cells are round to polygonal have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is elastotic.,biopsy from left breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1805789,recurrent lump right breast,biopsy from right breast lump,received wide excision specimen of right breast lump that measures 10x8x6cm.skin ellipse measures 6x1.5cm.on serial section single grey white fleshy mass lesion that measures 5.2x5.1x3.7cm distance from margins.superior margin: 2.5cminferior margin : 2cmmedial margin : 1.3cmlateral margin : 2.5cmdeep margin : 1.2cmmargins are ill defined slit like spaces present.few myxoid areas also noted.,section from lesion show numerous hyperplastic compressed ducts with few cystically dilated ductulolobular units that exhibit obliteration of lumen by atypical oval cells with vesicular nuclei and modertae amounts of cytoplasm . the stroma is cellular composed of predominantly short fascicles of spindle cells. adjacent breast shows apocrine and adenomyoepithelial adenosis.,biopsy from right breast lump:proliferative breast disease with focal ductal carcinoma in situ (dcis) approximately measures 1.2cm. all margins of resection are free of tumor.
MR1805881,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received 5 grey white linear cores measures 1 to 1.2 cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests cribriform and comedo necrosis pattern. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right brest lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1805896,left breast lump possibility of carcinoma breast,biopsy from left breast lump.,received 5 grey white linear cores measures 0.2 0.6cm. entire tissue processed.,section shows fragmented cores of breast parenchyma harboring infiltrative lesion arranged in cords nests and islands. the neoplastic cells are round to oval with abundant eosinophilic cytoplasm with moderately pleomorphic hyperchromatic nuclei. few are showing prominent nucleoli. mitotic activity discerned. stroma shows areas of necrosis hemorrhage and desmoplastic change.,biopsy from left breast lump:invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1805924,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received 5 grey white grey brown linear cores measures 1 to 1.2 cm. entire tissue processed.,section shows tumor cells in diffuse sheets. individual cells have hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. areas of hemorrhage and necrosis are seen.,right brest lump core biopsy :invasive carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1805936,left breast lump carcinoma breast.,biopsy from left breast lump.,received grey white linear cores measures 1 1.2cm. entire tissue processed.,section from the beast parenchyma shows a lesion arranged in sheets and nests. the cells are round to oval hyperchromatic nuclei abundant eosinophilic cytoplasm. adjacent stroma shows inflammatory infiltrate.,biopsy from left breast lump:infiltrating ductal carcinoma grade iiimodified bloom richardson score is 8 9(3+2+3).
MR1805963,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 1 1.3cm. entire tissue processed.,section shows linear cores of breast parenchyma with an infiltrating lesion arranged in nests cores and sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nuclei and prominent nucleoli. in few mitotic figures are discerned. stroma shows desmoplasia and lymphomononuclear infiltrates. ductal carcinoma in situ solid pattern noted.,biopsy from left breast lump.invasive carcinoma nst grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1805975,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received 3 grey white linear cores measures 0.6 1.2cm. entire tissue processed.,section shows multiple linear cores with infiltrating by neoplasm arranged in sheets nests and necrotic areas. the cells are round to oval hyperchromatic nuclei. scant to moderate cytoplasm. adjacent stroma shows lymphocytic infiltrates. mitotic figures are noted. areas of necrosis seen.,biopsy from right breast lump:infiltrating ductal carcinoma grade 2.modified bloom richardson score is 7 9(3+2+2).areas of necrosis seen.
MR1806005,right breast lump carcinoma breast.,biopsy from right breast lump,received 4 grey white linear cores measures 0.6 0.8cm. entire tissue processed.,section from the breast parenchyma shows a infiltrating lesion arranged in nests and sheets. the cells are round to oval hyperchromatic nuclei scant to moderate cytoplasm. adjacent stroma shows lymphoplasmacytic and mitotic figures seen.,biopsy from right breast lumpsuggestive of infiltrating ductal carcinoma nst nuclear grade iimodified bloom richardson score is (3+2+2) 7 9.repeat biopsy suggested to study hormonal status
MR1806010,left breast lump possibility of carcinoma breast.,left breast lump core biopsy.,received 4 grey white to grey yellow linear cores measures 0.8 1cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1806023,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received grey white to grey brown linear cores measures 0.8 1cm. entire tissue processed.,section shows breast parenchyma with foci atypical clusters of ducts epithelial cells. adjacent stroma shows inflammatory infiltrates composed of lymphocytes and desmoplasia,biopsy from right breast lump:atypical ductal clusters seenno definite evidence of malignancy suggest repeat.
MR1806027,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 3 grey white soft tissue bits measures 1 1.2cm. entire tissue processed.,sections from the breast parenchyma with infiltrating neoplasm arranged in sheets and nest. the cells are round to oval hyperchromatic nuclei few with prominent nucleoli. adjacent stroma shows inflammatory infiltrates. composed of lymphocytes. atypical mitotic figures are seen. lymphovascular invasion seen.,biopsy from left breast lump:infiltrating ductal carcinoma grade 2modified bloom richardson score is 7 9 (3+2+2).
MR1806037,left breast lump.,biopsy from left breast lump.,received 4 grey white to grey brown linear cores measures 1.1 1.3cm. entire tissue processed.,section shows infiltrating neoplasm arranged in sheets and nests. the cells are round to oval hyperchromatic nuclei. scant cytoplasm. adjacent areas show lymphocytic and necrotic areas . mitotic figures are seen.,biopsy from left breast lump:infiltrating ductal carcinoma grade iimodified bloom richardson son score is (3+2+2).ductal carcinoma in situ and areas of necrosis seenperineural invasion noted.
MR1806046,left breast lump malignant,biopsy from left breast lump.,received 5 grey white linear cores measures 0.8 1cm. entire tissue processed.,section from the breast parenchyma shows a lesion arranged in sheets and nests. the cells are round to oval hyperchromatic nuclei. scant to moderate eosinophilic cytoplasm. adjacent breast shows lymphocytes and plasma cells. mitotic figures are noted.,biopsy from left breast lump:infiltrating ductal carcinoma nst grade ii.modified bloom richardson score is 7 9(3+2+2).
MR1806084,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 0.8 1.2cm. entire tissue processed.,section from the breast parenchyma shows a lesion arranged in nests. the cells are round to oval hyperchromatic mild pleomorphism abundant eosinophilic cytoplasm. adjacent stroma shows lymphoplasmacytic infiltrate. areas shows desmoplasia.,biopsy from left breast lump:infiltrating ductal carcinoma nst grade ii.modified bloom richardson score is 7 9(3+2+2).
MR1806085,right breast lump carcinoma breast,biopsy from right breast.,received 4 grey white to grey brown linear cores measures 1 1.2cm. entire tissue processed.,section shows linear cores from the breast parenchyma shows a lesion arranged in nests. the cells are round to oval nuclei with scant to moderate clear cytoplasm prominent nucleoli. adjacent stroma shows dilated ducts lined by luminal and adluminal cells only with inflammatory infiltrates composed of lymphocytes plasma cells and neutrophils. areas of necrosis.,biopsy from right breast:suggestive of infiltrating carcinoma nst grade ii.in view large areas of necrosis and desmoplasia it is advisable to repeat biopsy for studying hormonal status.
MR1806086,left breast mass carcinoma breast.,left breast mass core biopsy.,received grey white linear cores bits measures 0.3 1cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1806088,case of left breast carcinoma.,a) left breast wide local excision post lumpectomy post nact.b) revised deep margin.c) revised superior margin.d) re revised superior margin.e) re re revised superior margin.f) re re re revised superior margin.g) left axillary dissection.,a) received skin covered soft tissue measures 6.5x3x2.5cm.skin ellipse measures 4.5x0.5cm. skin surface shows scar measures 2.5cm.cut surface is no obvious tumor seen grey white fibrotic area measures 1.3x1x1cm.distance from the margin.superior margin 1cm.inferior margin 1cm.medial margin 1.5cm.lateral margin 3cm.deep margin 0.8cm.b) received fibrofatty tissue measures 2.5x2x1cm. suture and ink seen. entire tissue processed.c) received fibrofatty tissue measures 3x2.5x0.5cm. one surface is sutured surface is inked green. entire tissue processed.d) received single fibrofatty tissue measures 2x2x1cm with string on one side. entire tissue processed.e) received fibrofatty tissue measures 3x2x1.5cm. entire tissue processed.f) received fibrofatty tissue measures 3x2x1cm. entire tissue processed.g) received fibrofatty tissue measures 8x6x4cm.largest lymph node measures 1.8x1x1cm.cut surface shows fatty infiltration.,sections studied show breast parenchyma with an infiltrating lesion arranged in sheets nests and small clusters. the cells are large oval having moderate amount of cytoplasm hyperchromatic pleomorphic nucleus and prominent nucleoli in few. mitotic figures are discerned. stromal is desmoplastic with scattered lymphomononuclear infiltrate.,a) left breast wide local excision post lumpectomy post nact:residual invasive ductal carcinoma grade 3.modified bloom richardson score is 8 9.tubular formation 3.nuclear pleomorphism 3.mitotic activity 2 8 9 ductal carcinoma in situ solid pattern is seen.tumor measures 2.0cm in greatest dimension.invasive component measures 1.5cm in greatest dimension.ductal carcinoma in situ measures 0.5cm in greatest dimension.lymphovascular invasion is noted.perineural invasion is not seen.superior inferior medial and deep margins show tumor deposits lateral margin is free of tumor.b) revised deep margin:show tumor deposits.c) revised superior margin:show tumor deposits.d) re revised superior margin:show tumor deposits.e) re re revised superior margin:show tumor deposits.f) re re re revised superior margin:show tumor deposits.g) left axillary dissection:three of the isolated sixteen lymph nodes show metastatic tumor deposits (3 16).perinodal spread is seen.
MR1806110,retroareola ill defined right breast ( birds 5),biopsy from right breast lesion.,received 4 grey white linear cores bits measures 0.5 1.5cm. entire tissue processed.,sections from the breast parenchyma shows a lesion arranged in cluster and scattered atypical cells. the cells are round to oval hyperchromatic nuclei scant to moderate cytoplasm. areas of necrosis. show ductal carcinoma in situ.,biopsy from right breast lesion:infiltrating carcinoma nst nuclear grade ii with ductal carcinoma in situ solid type present.
MR1806116,right breast lump possibility of carcinoma breast.left breast lump atypical fibroadenoma,a) right breastlumpb) left breast lump,a) received 4 grey white to grey brown linear cores measures 0.8 1.2cm. entire tissue processed.b) received 4 grey white linear cores measures 0.5 0.8cm. entire tissue processed.,a) sections from the breast parenchyma shows a lesion arranged in nests and sheets . the cells are round to oval vesicular with prominent nucleoli moderate cytoplasm. adjacent stroma shows lymphocytes and plasma cells. few mitotic figures are seenb) sections from breast parenchyma with few dilated ducts lined by luminal and adluminal cells. adjacent stroma show hyalinization and inflammatory cells.,a) right breast lump:invasive carcinoma of ductal origin grade iimodified bloom richardson score is ( 2+2+2)6 9b) left breast lump :benign breast disease favoring fibroadenoma
MR1806134,left breast lump carcinoma breast.,biopsy from left breast.,received 5 grey white linear cores measures 0.3 1cm.,section from the breast parenchyma shows a lesion arranged in sheets and nests. the cells are round to oval eosinophilic cytoplasm hyperchromatic nuclei. adjacent stroma shows inflammatory infiltrates. areas of necrosis and mitosis2 3 10 hpf.,biopsy from left breast:infiltrating ductal carcinoma.grade 2modified bloom richardson score is (3+2+2) 7 9.
MR1806158,liver sol metastasis.,biopsy from liver sol.,received grey white linear cores measures 0.5 to 0.8cm. entire tissue processed.,section studied shows fragments of fibrous lesion arranged in cords and nests. the cells are oval have moderately pleomorphic hyperchromatic nuclei inconspicuous nucleoli and abundant eosinophilic cytoplasm. mitotis is discerned. stroma shows foci of necrosis.,liver biopsy :metastatic carcinoma in a known case of carcinoma breast.
MR1806170,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 4 grey white to grey brown linear cores measures 1 1.2cm. entire tissue processed.,linear cores of breast tissue harboring a few dilated ducts lined by cuboidal cells lymphoplasmacytic inflammatory cell infiltrate noted. occasional large cells with eosinophilic cytoplasm and binucleation (apocrine metaplasia) noted.,biopsy from left breast lump:no definite evidence of malignancy in the section studied.***suggest repeat biopsy from representative area for confirmation of malignancy if clinically deemed necessary.
MR1806206,right breast lump malignant phylloides.,right breast lump core biopsy.,received multiple fragmented grey white to grey yellow linear cores measures 0.2 0.4cm. entire tissue processed,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets. the lesional cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. mitosis 6 8 10 hpf.,right breast lump biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1806210,left breast lump possibility of carcinoma breast.,left breast lump biopsy.,received 3 grey white to grey brown linear cores measures 1 1.2cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets. the lesional cells are round to oval having hyperchromatic nuclei and moderate eosinophilic cytoplasm. few cells showing clear cytoplasm. cells exhibit marked nuclear pleomorphism. mitosis is 5 6 10hpf.,left breast lump biopsy:invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+3+2).
MR1806212,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received 2 grey white to grey brown linear cores measures 1 1.2cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in tubules and cords. the lesional cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. cells exhibiting moderate nuclear pleomorphism. stroma is desmoplastic. mitosis is 5 6 10 hpf.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1806257,left breast lump possibility of carcinoma breast.,left breast lump core biopsy.,received 3 grey white grey yellow linear cores linear cores measures 0.5 0.8cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1806260,right cervical node possibility of metastasis.,biopsy right cervical node.,received multiple grey white linear cores measures 0.8 1.2cm. entire tissue processed.,section shows linear cores of tissue infiltrated by cords nests trabecular of neoplastic cells having round to oval mildly pleomorphic dark nuclei prominent nucleoli and moderate cytoplasm. few cells show intranuclear inclusion. mitotic figures 5 6 10 hpf. interspersed lymphoplasmacytic infiltrates noted.,biopsy right cervical node:metastatic carcinomatous depositsplease rule out primary from breast and lungsuggest ihc if clinically indicated.
MR1806286,carcinoma left breast.,a)left sentinel nodes.b)left mastectomy.,a)received soft tissue bits measures 6.8x3x1.7cm.isolated 2 lymph nodes.largest lymph nodes 1.5x1.4x0.6cm.b)received in : formalinprocedure : mastectomy laterality : lefttotal dimensions :medial to lateral :30cm superficial to deep :8cm superior to inferior:23cmskin ellipse : 20x15cm nipple : normal scar surgical defect : absenttumor : singletumour size : 6x4.5x4cm. grey white location of tumor : upper outer quadrantmargin of tumor : irregular ulceration deep margin :0.3cmmuscle : absentadjacent breast : fibrofatty axillary tail :4x3x2cmsize of largest node : isolated 4 lymph nodes,section studied from breast parenchyma harbours invasive neoplasm arranged in glandular tubules and focally sheets. the cells are pleomorphic with scant cytoplasm vesicular nuclei with 1 2 prominent nucleoli. atypical mitosis 8 9 10hpf present. extensive ductal carcinoma in situ comedo solid cribriform and focal papillary pattern. areas of necrosis present. stroma shows dense sclerosis with lymphoplasmacytic infiltrates.,left mastectomy:histological type:invasive carcinoma nos with extensive ductal carcinoma in situ.grade:3tumor measures maximum dimension 6 cm.invasive component measures2.2 cm.ductal carcinoma in situ measures 3.8cm.modified br score is 8 9tubule formation: 2 nuclear pleomorphism:3 mitotic figures:3 ductal carcinoma in situ solid cribriform comedo papillary. lymphovascular invasion is not identified.perineural invasion is not identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: sentinel lymph nodes 2 lymph nodes metastasis 0 (0 2).axillary lymph node 2 lymph nodes metastasis 1 (1 2).total nodes : 4 lymph nodes metastasis 1(1 4).perinodal extension not present.pathological stage: ypt2snpn1 summary: invasive carcinoma left mastectomy.tumor grade:3lymphnode status:sentinel lymph nodes :0 2.axillary lymph nodes :1 2.perinodal extension not present.total lymph nodes :1 4
MR1806304,carcinoma left breast.,biopsy from left breast lump.,received grey white multiple linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of breast parenchyma with a lesion arranged in nests cords and cribriform pattern. the lesional cells show moderate nuclear atypia hyperchromatic nuclei and moderate cytoplasm. extracellular mucinous areas present. areas of ductal carcinoma in situ present. areas of adenosis are seen.,biopsy from left breast lump:residual invasive carcinoma.
MR1806321,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received 3 fragmented grey white to grey brown linear cores measures 0.3 0.5cm. entire tissue processed.,section shows multiple fragments of breast parenchyma harboring lesion arranged in papillae with fibrovascular core and sheets. the lesional cells are oval to elongated with abundant eosinophilic cytoplasm. the nuclei are round to oval hyperchromatic few foci showing invasive component. the stroma showing dismoplastic changes and lymphocytic infiltrate.,biopsy from left breast lump:papillary neoplasm.*** needs larger tissue for further categorization.
MR1806360,carcinoma right breast post lumpectomy.,right modified radical mastectomy.,received in : formalinprocedure : right modified radical mastectomy laterality : right breast. total dimensions : medial to lateral : 15cm. superficial to deep : 5 cm. superior to inferior : 18 cm.skin ellipse : 11.5x7.5xcm. nipple : normalscar surgical defect : noted measuring 5cm. tumor size : fibrotic area tumor. margins of tumor : ill defined deep margin : 2 cm from fibrotic area.muscle : absent. adjacent breast : fibrofatty tissue axillary tail : 6x3.5cm.size of largest node :2x0.8x0.5cm. cut surface grey white.,section studied shows breast parenchyma with tiny focus of residual invasive lesion arranged in sheets and vague tubules. the cells are ovoid having moderate amount of pale eosinophilic cytoplasm and central to peripherally placed hyperchromatic nucleus. stroma shows desmoplasia with focal areas of foreign body giant cells and lymphomononuclear cell infiltrates. adjacent breast shows features of adenosis.,right breast modified radical mastectomy:tumor bed : shows residual invasive carcinoma with lobular features. surrounding breast parenchyma is fibrous with lymphoplasmacytic infiltration. histological type : residual invasive carcinoma with lobular features grade ii. tumor measures maximum dimension 0.3cm.invasive component measures 0.3cm. modified bloom richardson score is 6 9 tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 .............. 6 9 ................lymphovasuclar invasion is not seen. perineural invasion is not seen. posterior resected margin is free of tumor.nipple and areola is unremarkable.lymph nodes : 15 lymph nodes metastasis : 0. (0 15)summary :residual invasive carcinoma with lobular features tumor grade : 2lymph node status : 0 15
MR1806369,right breast lump possibility of carcinoma breast,biopsy from right breast lump,received 5 grey white linear cores measures 1.5 2cm. entire tissue processed.,section from breast parenchyma show a lesion arranged in nests and glandular pattern. the cells are round to oval irregular hyperchromatic nuclei scant to moderate cytoplasm. adjacent stroma shows inflammatory infiltrates. atypical mitotic figures are noted.,biopsy from right breast lump:invasive carcinoma nst nuclear grade iiimodified bloom richardson score is (3+2+3)8 9
MR1806457,right breast lump possibilities of carcinoma breast.,right breast core biopsy.,received multiple grey white to grey brown fragments of linear cores measures 0.3 to 0.7cm. entire tissue processed.,section shows small foci of tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy : invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). ductal carcinoma in situ of cribriform and comedo pattern with intermediate nuclear grade is seen.
MR1806471,case of right axillary lump since 2 years metastasis,biopsy from right axillary node.,received 3 grey white linear cores measures 1.5 2cm. entire tissue processed.,section shows multiple cores of tissue harboring infiltrating lesion arranged in sheets nests. the cells are round to oval having hyperchromatic nuclei moderate cytoplasm. mitosis are seen.,biopsy from right axillary node:metastatic carcinoma in a known case of carcinoma breast.
MR1806492,carcinoma left breast,a) left breast wide local excisionb) deep marginc) sentinel nodes,a) received lumpectomy specimen measures 8.5x8x4cm skin ellipse measures 6.5x3.2cmcut surface : ill defined lesion measures 4.2x3.22.5cm.distance from marginssuperior margin: 3cminferior margin : 3.3cmmedial margin : 2.7cmlateral margin : 3cmdeep margin : 0.3cmb) received fibrofatty tissue measures 2x1.5x0.8cmlargest lymph nodes measures 1.3x1.2x0.7cmc) received fibrofatty tissue measures 2x2x1cminked surface entire tissue processed.,section from the lesion show breast parenchyma harboring an invasive neoplasm composed of cells in glandular and papillary architecture floating in pools of mucin. the cells show moderate pleomorphism. round vesicular nuclei with coarse chromatin. surrounding parenchyma shows papillary and solid type ductal carcinoma in situ.,a) left breast conservative surgery:invasive mucinous carcinoma with cystic papillary features modified bloom richardson score is 7 9 grade ii.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2the tumor measures 4.2cm greatest dimensioninvasive carcinoma measures 3.5cmductal carcinoma in situ : solid and papillary type. measures 0.7cmlymphovascular invasion : indeterminateperineural invasion not identifiedall resected margins are free of tumorb) deep margin is free of tumor.c) sentinel nodes: 2 nodes examined are free of tumor 0 2.
MR1806568,carcinoma left breast.,a) left sentinel lymph node.b) breast conservative surgery wide excision.c) revised deep margin.,a) received fibrofatty tissue altogether measures 5x3x0.5cm. largest lymph node measures 1x0.8x0.4cm. entire tissue processed.cut surface grey white to grey brown.b) received lumpectomy specimen measures 7x4.5x2.5cm skin ellipse measures 2.8x1cmcut surface grey white lesion measures 2.6x2.3x1.5cm.distance from margins: superior margin:1.8 cminferior margin : 1.3cmmedial margin : 1.2cmlateral margin : 2.2cmdeep margin : 0.3cmc) received fibrofatty tissue measures 5x2.5x0.9cmowe cut surface inked.,a) sentinel lymph node:2 nodes no deposit of tumor.b) left breast conservative surgery wide excision:tumor is composed of pleomorphic cells with hyperchromatic nucleus and eosinophilic cytoplasm. tumor cells are arranged in clumps and groupstubular formation less than 10 3mitotic figures 2nuclear pleomorphism 2modified bloom richardson score is 7 9ductal carcinoma in situ present ( low grade) measuring 0.4cmlymphovascular invasion not presentperineural invasion present.resected margins: superior margin: free of tumor.inferior margin :free of tumor.medial margin :free of tumor.lateral margin :free of tumor.deep margin : inked margin is free from the tumor.c) resected inferior margin:the section shows fibrofatty tissue free from the tumor.,left breast conservative surgery wide excision:maximum dimension of tumor is 2.6cminvasive ductal carcinoma measuring 2.2cmductal carcinoma in situ low grade measuring 0.4cm resected margins superior inferior medial lateral margins are free from the tumor.revised deep margin free from the tumorsentinel lymph nodes :2 lymph nodes no deposits of tumor.
MR1806583,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received 4 grey white to grey brown linear cores measures 0.3 0.9cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by cords and trabeculae of neoplastic cells having pleomorphic round to oval hyperchromatic nuclei and moderate eosinophilic cytoplasm. mitotic figures 5 6 10hpf .stroma shows hyalinisation and lymphoplasmacytic infiltrates.,biopsy from left breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is 3+2+2 7 9
MR1806585,right breast lump possibility of carcinoma breast.,right breast lump biopsy.,received 4 grey white linear cores linear cores measures 1 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrating by a neoplastic lesion arranged in islands trabecular and cords composed of atypical cells having inconspicuous ovoid irregular dark nuclei inconspicuous nucleoli and moderate eosinophilic cytoplasm. focal area of ductal carcinoma n situ seen. comedonecrosis type. mitotic figures 8 9 10 hpf . stroma shows desmoplasia and areas of necrosis.,right breast lump biopsy.invasive ductal carcinoma grade 2.modified bloom richardson score is 3+2+2 7 9
MR1806591,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 0.6 0.7cm. entire tissue processed.,section shows invasive nests and sheets of round to oval cells arranged in ductal pattern showing moderate anisonucleosis hyperchromatic nuclei and prominent nucleoli. mitotic activity is discerned. the intervening stroma is desmoplastic.,biopsy from right breast lump:invasive carcinoma of ductal origin nst grade iimodified bloom richardson score is( 3+2+2) 7 9
MR1806615,right breast cystic lesion,biopsy from right breast lesion,received 3 tiny grey white linear cores measures 0.2 0.4cm. entire tissue processed,section show linear cores of breast parenchyma one of the cores showing invasive nests and sheets of round to oval cells arranged in ductal pattern showing moderate anisonucleosis hyperchromatic nuclei and prominent nucleoli. the adjacent cores show desmoplasia and mononuclear infiltrate.,biopsy from right breast lesion:suggestive of invasive carcinoma of ductal origin nst nuclear grade iinote: tumor fragment is very small suggest repeat biopsy for assessing erpr status.
MR1806644,right breast lump carcinoma breast.,right breast lump core biopsy.,received 5 grey white linear cores measures 1 1.5cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1806652,carcinoma left breast,a) wide local excision.b) left axillary sentinel node.,a) lumpectomy specimen measures 7.5x4.5x3cm. section shows ill defined lesion measures 3.2x20.6x1.9cm. distance from margins: superior margins: 1.2cminferior margin : 2.0cmmedial margin : 2.0cmlateral margin : 3.5cmdeep margin : 0.5cmb)received multiple fibrofatty tissue measures 3x2x1cm .largest lymph nodes measures 0.9x0.5x0.5cm. cut surface grey brown.,left breast conservative surgery:invasive ductal carcinoma ( nos)modified bloom richardson score is 7 9 grade ii.tubule formation 3 mitotic pigures 2 pleomorphism 2ductal carcinoma in situ not identifiedlymphovascular invasion not identified.perineural invasion not identifiedresected margins : superior margins: free of tumorinferior margin : free of tumormedial margin : free of tumorlateral margin : free of tumordeep margin : free of tumorsentinel nodes: sentinel lymph nodes : 5 nodes no metastatic deposit of tumor.(0 5),left breast wide local excision invasive ductal carcinoma ( nos)maximum dimension of tumor is 3.2x2.6x1.9cm grade iitubule formation 3 mitotic pigures 2 pleomorphism 2ductal carcinoma in situ not identifiedlymphovascular invasion not identified.perineural invasion not identifiedall resected margins are free of tumorsentinel lymph nodes :5 nodes. no metastatic deposits tumor.grade : pt2n0.
MR1806706,left breast lump carcinoma breast.,biopsy from left breast lump,received multiple grey white to grey brown linear cores measures 0.3 0.8cm. entire tissue processed.,section shows breast parenchyma cores harboring an invasive neoplasm in sheets with moderate eosinophilic cytoplasm marked nuclear pleomorphism and increased mitosis. stroma is desmoplastic with scattered inflammatory infiltrate. few ducts show comedo type ductal carcinoma in situ.,biopsy from left breast lump:invasive carcinoma nst grade iii.modified bloom richardson score is 3+3+3 9 9.
MR1806712,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 0.8 1.2cm. entire tissue processed,section shows sheets of dysplastic ductal cells invading the fibrous stroma showing moderate pleomorphism and hyperchromatic nuclei with prominent nucleoli. the intervening stroma shows mononuclear infiltrates. ductal carcinoma in situ with comedonecrosis seen.,biopsy from left breast lump:invasive carcinoma of ductal origin nst modified bloom richardson score is 2+2+3 7 9 grade iiductal carcinoma in situ with comedo necrosis seen.
MR1806729,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received 5 grey white to grey brown linear cores measures 0.7 1cm. entire tissue processed.,section shows multiple fragmented cores of breast parenchyma harboring lesion arranged in sheets cords and islands. the lesion cells are round to oval with abundant eosinophilic cytoplasm. the nuclei showing mild to moderate pleomorphism. areas of hemorrhage and necrosis seen. mitotic activity discerned.,biopsy from right breast lump:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1806736,left breast lump carcinoma breast.,left breast lump core biopsy.,left breast lump core biopsy.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy. :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1806739,right breast lump possibility of carcinoma breast.,right breast lump.,received 5 grey white linear cores measures 0.5 1cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in tubules and cords. the neoplastic cells have round to oval hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm. extensive areas of hyalinisation noted. mitosis is discerned.,right breast lump:invasive ductal carcinoma grade 1modified bloom richardson score is 5 9tubule formation : 1nuclear pleomorphism : 2mitotic figures : 2 5 9
MR1806773,right breast lump carcinoma breast.,biopsy from right breast lump,received 6 grey white to grey brown linear cores measures 0.5 1cm. entire tissue processed.,section from breast linear cores shows a neoplastic lesion arranged in cords and islands composed of pleomorphic cells having round to oval dark nuclei prominent nucleoli and moderate eosinophilic nucleoli. mitotic figures seen 6 7 10 hpf along with atypical mitosis. stroma shows lymphoplasmacytic infiltrates and few dilated ducts. focal areas of necrosis seen.,biopsy from right breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9(3+2+2).
MR1806784,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 3 grey white linear cores measures 0.5 0.8cm. entire tissue processed.,section shows linear cores of breast parenchyma showing dilated ducts lined by columnar cells. few sheets show hyperplasia. stroma is cellular and shows plump spindle cells having ovoid dark nuclei prominent nucleoli and moderate cytoplasm. nuclear atypia is noted. mitotic figures 1 2 10 hpf.,biopsy from left breast lump:biphasic neoplasmpossibility considered are benign borderline phyllodes tumorrequire excision biopsy.
MR1806790,left breast lump carcinoma breast.,biopsy from left breast.,received 6 grey white linear cores measures 0.8 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as islands and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is scant.,biopsy from left breast:invasive carcinoma nst.modified bloom richardson score is 7 9 grade 2 tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1806827,right breast axilla lump carcinoma breast.,biopsy from right breast lump,received 4 grey white linear cores measures 0.7 1cm. entire tissue processed.,multiple areas of breast tissue harboring invasive neoplasm in cords nests and poorly formed glands cells show moderate pleomorphism increased mitosis eosinophilic cytoplasm. stroma is desmoplastic. foci of microcalcification also seen. perineural invasion seen.,biopsy from right breast lump:invasive carcinoma nst grade iimodified bloom richardson score is 6 9(2+2+2).perineural invasion present.
MR1806833,right breast lump carcinoma breast.,biopsy from right breast lump,received 6 grey white linear cores measures 0.8 1.2cm. entire tissue processed,multiple cores of fibrocollagenous tissue with infiltrative neoplasm in sheets and nests. the cells show moderate nuclear pleomorphism and hyperchromasia and increased mitosis. stroma is deoplastic and shows inflammatory cell infiltration.,biopsy from right breast lump:invasive carcinoma nst grade iimodified bloom richardson score is 2+2+3 7 9.
MR1806846,known case of carcinoma left breast post chemo.,biopsy from left breast lesion.,received 4 grey white linear cores measures 0.3 0.8cm. entire tissue processed,linear cores of fibrocollagenous tissue seen with a few entrapped benign ducts.,biopsy from left breast lesion:no evidence of neoplasia in the tissue submitted.
MR1806850,left breast lump possibility of carcinoma breast.,left breast core biopsy.,received 4 grey white linear cores measures 1.4 1.6cm. entire tissue processed.,section shows linear cores of breast parenchyma showing infiltrating lesion arrange in tubules cords and nests. the lesion cells are round to oval with abundant eosinophilic cytoplasm. mitotic activity discerned. stroma stroma showing lymphocytic infiltrate and desmoplastic change.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score 7(3+2+2).
MR1806862,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 3 grey white liner cores measures 0.8 1.3cm. entire tissue processed.,section shows multiple cores of breast tissue harboring an invasive neoplasm nests and cords composed of atypical cells with moderate pleomorphism. numerous cyst like dilated spaces with neoplastic tumor cells seen.,biopsy from left breast lump:invasive carcinoma nst.modified bloom richardson score is 2+2+3 7 9 grade ii.
MR1806879,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 4 grey white soft tissue bits measures 0.4 0.8cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in nests and glands showing moderate nuclear pleomorphism. areas show solid and cribriform type ductal carcinoma in situ and calcification. stroma shows desmoplasia with areas of necrosis and crush artifacts.,biopsy from left breast lump:invasive ductal carcinoma with ductal carcinoma in situ.grade i modified bloom richardson score is 2+2+1 5 9.
MR1806947,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received 5 grey white linear cores measures 0.8 1.2cm. entire tissue processed.,section show multiple cores of breast parenchyma harboring infiltrating lesion arranged in nests and islands. the lesional cells are round to oval having hyperchromatic nuclei and abundant eosinophilic cytoplasm. cells exhibit moderate nuclear pleomorphism. mitosis 4 5 10 hpf.,biopsy from left breast lump:invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1806949,right breast lump carcinoma breast.,right breast core biopsy.,received 5 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section show linear cores of tissue harboring a neoplastic lesion arranged in nest cords sheets. with reaction of stroma surrounding the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. stroma show desmoplasia with scattered inflammatory cells.,right breast core biopsy :invasive carcinoma nst grade ii.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1806950,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received 4 grey white to grey brown linear cores measures 0.8 1.3cm.,section shows cores of breast tissue harboring an invasive neoplasm in nests and tubules. the cells show moderate nuclear pleomorphism eosinophilic vacuolated cytoplasm and increased mitosis stroma is desmoplastic. tumor infiltrates the fat areas of hemorrhage seen.,biopsy from right breast lump:invasive carcinoma of ductal origin nst.modified bloom richardson score is 2+2+3 7 9.
MR1806961,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received 3 grey white linear cores measures 1 1.4cm. entire tissue processed.,section shows cores of fibrocollagenous tissue harboring an invasive neoplasm is nests and cords composed of atypical cells with moderate nuclear pleomorphism and increased mitosis. stroma is desmoplastic.,biopsy from left breast lump:invasive carcinoma of ductal origin nstmodified bloom richardson score is 3+2+1 6 9 grade ii
MR1807006,right breast lump carcinoma breast.,biopsy from right beast lump.,received 4 grey white linear cores measures 1.5 2cm. entire tissue processed.,section shows linear cores of fibrofatty tissue harboring a neoplastic lesion arranged in cores and sheets . the cells have pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. stroma show desmoplasia. mitotic figures are 2 3 10hpf.,biopsy from right breast lump:invasive carcinoma with lobular features nst modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1807016,left breast lump carcinoma breast post mrm,biopsy from left breast lump.,received 7 grey white to grey brown linear core measures 0.3 1cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in cords and nests. the lesional cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. the cells exhibit moderate nuclear pleomorphism. stroma is desmoplastic .mitosis 2 3 10hpf.,biopsy from left breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1807056,right breast lump to rule out malignancy.,biopsy from right breast lump,received multiple grey white to grey brown linear ores measures 0.3 0.5cm. entire tissue processed.,section shows cores of breast tissue with one of the core showing sheets and aggregates of atypical cells surrounded by dense lymphoplasmacytic infiltrate. the cells show moderate pleomorphism increased n c ratio and hyperchromatic nuclei. areas of crush artifacts present.,biopsy from right breast lump:vary tiny clusters of malignant cells poorly differentiated carcinoma.tissue may be inadequate for further workup.
MR1807071,right breast lump possibility of carcinoma breast.,biopsy from right breast lump,received multiple fragments cores measures 0.3 0.6cm. entire tissue processed.,section shows cores of breast parenchyma with a lesion arranged in sheets and nests. the cells show moderately pleomorphic nuclei and moderate cytoplasm. mitotic figures discerned. intervening stroma shows lymphocytic infiltrates.,biopsy from right breast lump:invasive carcinoma nst grade iimodified richardson score is 6 9(32+2+1).
MR1807099,carcinoma left breast,a) left breast sentinel lymph nodeb) wide excision,a)received fibrofatty tissue measures 2x1.7x0.8cm. largest lymph node measures 1.4x1.2x0.8cm cut surface fatty infiltration.b) received lumpectomy specimen measures 5.2x4.5x3.4cmcut surface shows grey white ill defined lesion measures 1.9x1.6x1.4cm. skin ellipse measures 3x0.5cmdistance from marginssuperior margin: 2cminferior margin :1.8cmmedial margin :1.6cmlateral margin :1.9cmdeep :0.3cmintramammary nodes 3 nodes the nodes varying from 0.3 to 8cm,a) sentinel lymph node : 3 nodes no metastatic deposit of tumor.b)wide excision:invasive ductal carcinoma maximum dimension of the tumor is 1.9x1.6x1.4cm.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2lymphovascular invasion presentperineural invasion not identifiedductal carcinoma in situ not identifiedintra mammary nodes 2 nodes show metastatic deposit of tumor out of 3 nodes perinodal spread present.,wide excision:maximum dimension of tumor is 1.9x1.6x1.4invasive ductal carcinoma grade iilymphovascular invasion is presentall resected margins are free of tumorintramammary nodes 2 nodes show metastatic deposit of tumor out of 3 nodes perinodal spread presentsentinel nodes:3 nodes no deposit of tumor.
MR1807100,right breast lump carcinoma breast.,right breast core biopsy.,received 4 grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section show linear cores of tissue harboring a neoplastic lesion arranged in cords sheets and islands. the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. stroma show desmoplasia with few inflammatory cells.,right breast core biopsy :invasive carcinoma nst grade ii.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1807108,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received 5 grey white linear cores measures 0.5 1cm. entire tissue processed.,linear cores of breast tissue showing foci of solid ductal carcinoma in situ. the intervening stroma is fibromyxoid.,biopsy from left breast lump:ductal carcinoma in situ( intermediate grade)
MR1807141,known case of carcinoma breast post mrm.,biopsy from right breast,received 2 grey white to grey brown linear cores measures 0.8 1.2cm. entire tissue processed,linear cores of breast tissue harboring infiltrating lesion arranged in cords and nests. the lesional cell are round to oval having hyperchromatic nuclei and moderate cytoplasm. few cells showing eccentrically placed nuclei and moderate vacuolated cytoplasm. stroma is desmoplastic .cells exhibit moderate nuclear pleomorphism..,biopsy from right breast:invasive carcinoma with lobular features grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1807172,left breast lump.,left breast core biopsy.,received 4 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section show cores of tissue with a neoplastic lesion arranged in nest and sheets. the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. stroma show desmoplasia. areas of necrosis noted.,left breast core biopsy :suggestive of invasive carcinoma nst. grade imodified bloom richardson score is 5 9tubule formation : 3nuclear pleomorphism : 1mitotic figures : 1 5 9
MR1807188,left breast lump carcinoma breast.,left breast core biopsy.,received 5 grey white core measures 0.8 to 1.3cm. entire tissue processed.,section show linear cores of tissue arranged in sheets and cords the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. stroma show desmoplasia with scattered inflammatory cells. mitotic figures seen.,left breast core biopsy :invasive carcinoma nst grade iimodified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1807189,left breast lesion carcinoma breast.,left breast lump.,received 3 cores of tissue measures 0.8 to 1.2cm. length.,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1807259,left breast carcinoma.,left breast left modified radical mastectomy.,received in : formalinprocedure : left modified radical mastectomy.laterality : left breasttotal dimensions : medial lateral : 20 cm superficial deep : 3.5 cm superior inferior : 16 cmskin ellipse : 13x6 cmnipple : normalscar surgical defect : upper inner quadrant 7.5 cm in length.no obvious tumor grey white firm area seen measuring :3x1x1 cmdeep margin : 0.3 cmmuscle : present. 9x7 cmadjacent breast : fibrofatty tissueaxillary tail : no,multiple sections from lesion show breast parenchyma harboring foci of multinucleated giant cell reaction. perductal lymphocytic inflammatory cell infiltrate seen.section from deep margin shows fragment of fibrovascular tissue with no specificant patholoy. section from nipple areola is free of tumor.,no residual tumor status post lumpectomy left breast (vide reference no:sr18 1652)foreign body giant cell reaction seen.no lymphovascular invasion is seen. no perineural invasion is seen. deep margin is free of tumor. nipple areola is free of tumor.
MR1807296,right breast lesion suspicious.,right breast biopsy.,received 5 grey white linear cores measures 0.4 to 0.7cm. entire tissue processed.,section shows multiple cores of breast parenchyma showing ducts with epithelial proliferation the cells are round to oval with moderate amount of eosinophilic cytoplasm. nuclear are round to oval hyperchromatic and showing moderate nuclear pleomorphism nucleoli are inconspicuous. all ducts are lined by myoepithelial cells. stroma shows desmoplastic change and few lympho plasmacytic infiltrated. no definite evidence of invasive malignancy is seen.,right breast biopsy :shows ductal carcinoma in situ of comedo solid and cribriform type with intermediate nuclear grade. no definite evidence of invasive malignancy is seen.
MR1807304,right breast lump carcinoma breast.,right breast lump biopsy.,received 3 grey white to grey yellow linear cores measures 0.3 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating neoplasm arranged in cords. the lesional cells have round to irregular nucleus prominent nucleoli and moderate cytoplasm. mitotic activity noted.,right breast lump biopsy :invasive ductal carcinoma grade ii.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1807328,right lump possibility of carcinoma breast.,biopsy from right breast,received 4 grey white grey yellow linear cores measures 1 1.5cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords clusters and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is elastotic.,biopsy from right breast:infiltrating ductal carcinoma grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1807370,right breast lump carcinoma breast.,right breast lump core biopsy.,received 5 grey white linear cores measures 0.3 to 1 cm. entire tissue processed.,section show tumor cells in sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. few cells are showing bizarre nuclei.,right breast lump core biopsy :invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+3+2).
MR1807372,left breast lump possibilities of carcinoma breast.,left breast lump.,received 6 grey white linear cores measures 0.5 to 0.8cm. entire tissue processed.,section show linear cores of tissue harboring a neoplastic lesion arranged in sheets. the cells are moderately pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. stroma show desmoplasia. areas of necrosis seen. mitotic figures are 8 10 10hpf.,left breast lump biopsy :invasive carcinoma nst grade iiimodified bloom richardson score is 9 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 3 9 9 area of necrosis seen.
MR1807391,carcinoma right breast.,a) right breast lump conservative surgery.b) revised deep margin.c) revised medial margin.d) lymph nodes.e) left breast lumpectomy.,a) received lumpectomy specimen measures 8x6.5x4 cm. skin is absent. cut surface shiows grey white lesion measures 3.5x3x2 cm.distance from different margins :superior margin : 1.4 cminferior margin : 2 cmmedial margin : 0.5 cm fibrotic area.lateral margin : 1.3 cmdeep margin : 0.5 cmb) received single fibrofatty tissue measures 5x4x1 cm entire tissue processed.c) received fibrofatty tissue measures 3x2x1.5 cm entire tissue processed.d) received fibrofatty tissue measures 7x5x2 cm largest lymph node measures 1x1x1 cm cut surface is grey white.e) received single fibrofatty tissue measures 1x1x0.5 cm entire tissue processed.,sections from the breast showsinvasive neoplasm with cells arranged in linear cords and indian file pattern. the cells show moderate pleomorphism hyperchromatic nuclei and prominent nucleoli. stroma is desmoplastic. foci show lobular carcinoma in situ measures 0.5 cm.,a) right breast lump conservative surgery :invasive carcinoma with lobular carcinoma features.modified br score is 3+2+1 6 9 grade ii.tumor measures 3.5 cm.invasive component measures 3 cm. in situ component measures 0.5 cm.lymphovascular invasion is present.perineural invasion not identified.lobular carcinoma in situ present measures 0.5 cm.medial margin shows atypical cells. however inked margin is free of tumor.superior margin shows features of invasive lobular carcinoma. however inked margin is free of tumor.b) revised deep margin : is free of tumor and shows epithelial hyperplasia.c) revised medial margin : a small focus of atypical cells away from the inked margin.however all inked margins are free of tumor.d) lymph nodes : 3 out of 10 nodes shows tumor deposits. largest measures 0.4 cm. extranodal extension is not identified.e) left breast lumpectomy. sections from left breast lump show secretory changes. no insitu or invasive carcinoma seen. summary: total dimension of carcinoma is 3.5 cm.invasive lobular carcinoma is 3 cm. lobular carcinoma insitu is 0.5 cm.lateral margin is free of tumor. superior medial and deep margins shows atypical cells. however inked margins are free of tumor.revised deep margin and medial margin are free of tumor. 3 lymph nodes out of 10 shows metastatic deposits of tumor.pathological stage : pt2n1
MR1807393,right breast lump carcinoma breast.,right breast biopsy.,received 4 grey white linear cores measures 1 to 2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring infiltrating lesion arranged in cords tubules and nests. the individual neoplastic cells consists of round to oval moderately pleomorphic hyperchromatic nuclei with inconspicuous nucleoli mitotic activity discerned. adjacent stroma shows desmoplastic change and lymphoplasmacytic infiltrate.,right breast biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1807412,right breast lump carcinoma breast.,right breast lump.,received 4 grey white linear cores measures 0.5 to 0.8cm. entire tissue processed.,section show linear cores of tissue harboring a neoplastic lesion arranged in nest cords sheets. the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. stroma show desmoplasia with scattered inflammatory cells. mitotic figures seen.,right breast lump core biopsy :invasive carcinoma nst grade ii modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1807413,right breast lump possibility of carcinoma breast.,right breast lump.,received grey white to grey brown 4 linear cores measures 0.5 to 0.8cm. entire tissue processed.,section show linear cores of breast parenchyma harboring a neoplastic lesion arranged in sheets. the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm stroma show desmoplasia. mitotic figures seen.,right breast lump core biopsy :invasive carcinoma nst grade ii.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1807421,left breast lump carcinoma breast.,left breast lump,received 4 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section show linear cores of breast tissue harboring a neoplastic lesion arranged in sheets having markedly pleomorphic round hyperchromatic nuclei and moderate amount of cytoplasm. stroma show dense lymphocytic infiltrate. mitotic figures discerned.,left breast lump invasive carcinoma nst grade ii modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 7 9
MR1807456,case of right breast carcinoma.,a) right sentinel lymph node ( blue node)b) blue +hot nodec) right breast wide excision.,a) received fibrofatty tissue measures 3x1x0.8cmisolated 2 lymph nodes largest lymph nodes measures 1.5x0.8x0.6cm. cut surface grey white.b) received 2 lymph nodes largest lymph nodes measures 1x0.8x0.5cm. cut surface grey white.c) received lumpectomy specimen measures 7.5x5.5x3cm.skin ellipse measures 7.5x5.5x3cm.skin ellipse measures 4.5x1.5cm.on serial section grey white lesion identified measures 2x1.5x1cm..distance from margins: superior margin:1 cminferior margin :2.2 cmmedial margin : 1.5cmlateral margin : 4cmdeep margin : 1.6cm,a) sentinel lymph nodes: blue nodetwo nodes 2 nodes. no deposit of tumor.b) sentinel nodes : blue and hot node:2 nodes no deposit of tumor.c) right breast wide excision:multiple section show tumor composed of pleomorphic cells with vesicular to hyperchromatic nucleus with eosinophilic cytoplasm. clumps of tumor cells are surrounded by pools mucin.modified bloom richardson score is 6 9 grade ii.tubule formation 3nuclear pleomorphism 2mitotic figures 1ductal carcinoma in situ not present.lymphovascular invasion not presentperineural invasion not presentall resected margins are free of tumor.,breast conservation surgery:mucinous carcinoma maximum size of tumor measures 2x1.5cm grade iiductal carcinoma in situ not identified.lymphovascular invasion not identified.all resected margins are free of tumorsentinel lymph nodes:4 nodes no deposit of tumorpathological stage:pt1n0
MR1807493,left breast lump.,left breast biopsy.,received 3 grey white linear core measures 0.8 to 1.2cm. entire tissue processed.,section show linear cores of breast parenchyma infiltrated by a neoplastic lesion arranged in islands and sheets of cells having pleomorphic ovoid hyperchromatic nuclei some with prominent nucleoli moderate eosinophilic cytoplasm. admixed are seen few cells arranged in nests abundant vacuolated cytoplasm. mitotic figures are frequent. stroma shows desmoplasia and hyalinisation.,left breast biopsy :invasive ductal carcinoma grade 3.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR1807510,right breast lesion malignancy.,right breast lesion biopsy.,received multiple grey white fragments cores 0.2 to 0.5cm. entire tissue processed.,section shows cores of breast parenchyma with a lesion arranged in tubules and cords. the cells show moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. ductal carcinoma in situ solid and cribriform pattern is noted. intervening stroma shows extensive hyalinization. frequent mitotic figures noted.,right breast lesion biopsy :invasive carcinoma with component of ductal carcinoma in situ. grade 2 modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1807533,left breast lump carcinoma breast.,left breast lump.,received 4 grey white linear cores 0.8 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a lesion arranged in cords and nests. the individual cells consisting of round to oval pleomorphic hyperchromatic nuclei with inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. mitotic activity discerned. intervening stroma shows desmoplastic change and congested blood vessels.,left breast lump biopsy :invasive ductal cell carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1807534,left breast lump possibility of carcinoma.,left breast lump.,received multiple fragmented grey white to grey brown measures 0.2 to 0.6cm. entire tissue processed.,section shows breast parenchyma with a lesion arranged in sheets nests and cords. the cells show moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. frequent mitotic figures noted. adjacent stroma shows lymphoplasmacytic infiltrates.,left breast lump biopsy :invasive ductal carcinoma nst grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 area of necrosis seen.
MR1807544,left breast lump carcinoma breast.,left breast lump.,received 5 grey white fragments cores measures 0.2 to 0.5cm. entire tissue processed.,section show cores of breast parenchyma with extensive necrosis and one core showing a lesion arranged in nests and cords. the cells show moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. frequent mitosis noted. foci of calcification noted.,left breast lesion biopsy :suggestive of invasive carcinoma nst. grade 2 modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 with extensive necrosis.note as the tissue is scanty in the present block it would be difficult to study hormonal statussuggest repeat biopsy
MR1807565,left breast lump carcinoma breast.,section shows cores of breast parenchyma with a lesion arranged in tubules nests.,received 5 grey white linear cores 0.8 to 1.5cm. entire tissue processed.,section shows cores of breast parenchyma with a lesion arranged in tubules nests and cords. the cells show moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. ductal carcinoma in situ with papillary and comedo necrosis noted. stromal desmoplasia is noted.,left breast lesion biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 ductal carcinoma with comedo necrosis seen.
MR1807587,left supraclavicular node metastases.,biopsy from left supraclavicular node.,received multiple fragmented cores. 0.4 to 0.3cm. entire tissue processed.,section shows cores of fibro collagenous tissue harboring lesion arranged in diffuse sheets. the individual neoplastic cells consisting of round to oval hyperchromatic cells moderately pleomorphic nuclei few with nucleoli and abundant eosinophilic cytoplasm. mitotic activity discerned intervening stroma shows lymphocytic infiltrate.,left supraclavicular lymph node biopsy :positive for malignancy.suggestive of metastatic deposits in known case of carcinoma breast.
MR1807601,right breast lump carcinoma breast.,right breast lump biopsy.,received 4 grey white brown linear cores 0.8 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring infiltrating lesion arranged in nests trabecular and tubules the individual neoplastic cells consists of round to oval markedly pleomorphic hyperchromatic nuclei with inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. mitotic activity discerned. adjacent stroma shows desmoplastic change and lymphocytic.,right breast lump biopsy :invasive ductal cell carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1807614,carcinoma right breast.,right modified radical mastectomy,received in : formalinprocedure : modified radical mastectomy laterality : righttotal dimensions : medial to lateral :20cm superficial to deep :5 cm superior to inferior :18cmskin ellipse :13.5x10.5cmnipple :normalscar surgical defect :not seentumor : singletumor size : 6x6x4.5cm location of tumor : central and outer quadrantmargins of tumor : ill defined deep margin :1.2cmmuscle : 3x1.5x0.5adjacent breast : fibrofatty tissue axillary tail : 10x10x3cmtotal number of nodes : 16 nodessize of largest : 2.5x2x1.5cm cut surface grey white.,section show pleomorphic picture predominantly spindle shaped cells with vesicular nuclei and prominent nucleoli moderate cytoplasm. few round to oval cells are seen. interspersed are plenty of osteoclast type of giant cells with 15 30 nucleoli.the spindle shaped cells show high mitotic rate of 15 20 hpf. in few areas spindle cells are arranged in fascicles and whorled pattern. areas of necrosis and hemorrhage present in the tumor. no glandular epithelium seen.,right breast right modified radical mastectomy:suggestive of an undifferentiated malignancy high grade mitotic figures : 15 20 hpf tumor measures 6x6cm in greatest dimension is located in the central outer quadrant.ductal carcinoma in situ not identified.lymphovascular invasion indeterminateperineural invasion presentposterior resection margin is free of tumor.nipple and areola is unremarkable lymph nodes 1 lymph node shows benign ductal epithelial cells out of 16 lymph nodes.report on ihc to follow
MR1807619,right breast lump carcinoma breast.,right breast lump biopsy.,received 5 grey white brown linear cores 0.8 to 1.2cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in cords nests and sheets. the individual neoplastic cells consists of round to oval moderately pleomorphic hyperchromatic nuclei with inconspicuous nucleoli and abundant eosinophilic cytoplasm. mitotic activity discerned. adjacent stroma shows desmoplastic change and lymphocytic.,right breast lump core biopsy :invasive ductal cell carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1807640,right breast lump carcinoma breast.,right breast lump biopsy.,received 4 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section shows cores of breast parenchyma with a lesion arranged in sheets nests and cords. the cells have moderate anisonucleosis hyperchromatic nuclei and moderate cytoplasm. intervening stroma shows desmoplasia.,right breast lump :invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 ...........
MR1807683,left breast lump carcinoma breast.,left breast lump biopsy.,received 4 grey white to grey brown fragment cores measures 0.5 to 1cm. entire tissue processed.,section shows cores of breast parenchyma with a lesion arranged in sheets and nests. the cells show moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. frequent mitotic figures noted. intervening stroma shows dense lymphoplasmacytic infiltrates. areas of hemorrhage noted. areas of necrosis seen.,left breast lump biopsy :invasive carcinoma nst grade 3 modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 ...........areas of necrosis seen.
MR1807698,left breast lump possibilities of carcinoma breast.,left breast lump biopsy.,received 3 grey white linear cores measures 0.8 to 1.3cm. entire tissue processed.,section show linear cores of breast parenchyma with a lesion arranged in nests and cords. the cells show moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. the intervening stroma shows desmoplasia.,left breast lump biopsy :suggestive of invasive carcinoma nst grade iimodified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1807699,left breast lump possibilities of carcinoma breast.,left breast lump biopsy.,received 3 grey white linear cores measures 0.8 to 1.2cm. entire tissue processed.,section show linear cores of breast parenchyma infiltrated by neoplastic cells arranged in a glandular pattern. the neoplastic cells have round to irregular pleomorphic hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm. mitotic is discerned.,left breast lump biopsy :invasive ductal carcinoma grade iimodified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1807708,right breast lump biopsy.,right breast lump biopsy.,received 6 grey white linear cores measures 0.8 to 1.2cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in tubules and nests. the lesional cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. stroma shows desmoplasia mitosis 6 7 10hpf. areas of ductal carcinoma in situ (cribriform) type noted.,right breast lump biopsy :suggestive of invasive ductal carcinoma grade 2.foci of ductal carcinoma in situ noted. modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 ...........
MR1807720,left breast lump possibilities of carcinoma breast.,biopsy from left breast lump.,received 5 grey white linear core measures 0.8 to 1.2 cm. entire tissue processed.,section show linear cores of breast parenchyma showing infiltrated by small nests and sheets of neoplastic cells having pleomorphic ovoid dark nuclei prominent nucleoli and moderate eosinophilic cytoplasm. bi nucleate and multinucleated tumor giant cells seen. mitotic figures are frequent. stroma shows extensive fibrosis and lymphoplasmacytic infiltrates.,left lump biopsy :invasive ductal carcinoma grade 3.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR1807728,right breast lump carcinoma breast.,right breast lump.,received 3 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section show linear cores of breast tissue showing a lesion infiltrating the stroma composed of nests and sheets of dysplastic ductal cells showing moderate anisonucleosis hyperchromatic nuclei and moderate eosinophilic cytoplasm. mitotic activity is discerned. the intervening stroma show desmoplasia.,right breast lump :invasive carcinoma of ductal origin nst. grade iimodified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1807734,left breast lump possibilities of carcinoma breast.,left breast lump biopsy.,received fragmented grey white cores measures 0.4 to 6cm. entire tissue processed.,section show linear cores of breast parenchyma with a lesion showing invasive sheets and nests oof dysplastic ductal cells showing moderate pleomorphism hyperchromatic nuclei and prominent moderate nucleoli. mitotic activity increased. areas of necrosis seen. focal ductal carcinoma in situ with comedo necrosis seen. the intervening stroma show moderate desmoplasia with mononuclear infiltrates.,left breast lump biopsy :invasive carcinoma of ductal origin nst grade iimodified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 areas of necrosis and ductal carcinoma in situ seen.
MR1807737,right breast lump carcinoma breast.,right breast lump biopsy.,received multiple fragmented cores grey white to grey brown measures 0.5 to 0.8cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in sheets lubules and nests. the lesional cells have round nucleus coarse chromatic and moderate cytoplasm. areas of necrosis is seen.,right breast lump biopsy :invasive ductal carcinoma grade ii. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1807744,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section show linear cores of breast parenchyma showing bundles of plump stromal cells exhibiting moderate pleomorphism and elongated nuclei against a myxoid background. there is paucity of ductal structures.,left breast lump possibility of carcinoma breast :suggestive of fibroepithelial lesion.suggest excision biopsy for definite opinion.
MR1807745,right breast lump carcinoma breast.,right breast lump.,received 4 grey white linear cores measures 0.5 to 2cm. entire tissue processed.,section show linear cores of breast parenchyma showing invasive nests and sheets of dysplastic ductal cells showing moderate pleomorphism hyperchromatic nuclei and prominent moderate nucleoli. the intervening stroma show moderate desmoplasia and mononuclear infiltrates.,right breast lump biopsy :invasive carcinoma of ductal origin nst grade iimodified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1807785,right breast lump carcinoma breast.,right breast lump biopsy.,received 3 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section show linear cores of breast parenchyma showing an infiltrative lesion composed of nests and sheets round to oval ductal cells showing moderate pleomorphism hyperchromatic nuclei with prominent nucleoli. mitotic activity is discerned. the intervening stroma is desmoplastic.,right breast lump biopsy :invasive carcinoma of ductal origin nst grade iimodified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1807798,left breast lump possibility of carcinoma breast.,left breast lump biopsy.,received 4 grey white linear cores measures 0.1 to 1.2cm. entire tissue processed.,received 4 grey white linear cores of breast parenchyma with extensive areas of ductal carcinoma in situ (comedo and solid pattern) with suspicous foci of invasive neoplasm.the lesional cells have pleomorphic round to irregular hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm. mitotic figures discerned.,left breast lump biopsy :extensive ductal carcinoma in situ with comedonecrosis and small suspicious focus of invasion. suggest repeat biopsy to rule out invasion.
MR1807876,left breast lump carcinoma breast.,left breast biopsy.,received 4 linear cores grey white to grey brown soft tissue bits measures 0.5 1cm. entire tissue processed.,section shows fragments of fibrocollagenous tissue harboring lesion arranged in sheets and nests. the individual cells are consisting of round to oval moderately hyperchromatic nuclei with inconspicuous nucleoli and abundant amount of eosinophilic cytoplasm. mitotic activity discerned. intervening stroma showing areas of hemorrhagic and lymphoplasmacytic infiltrate.,left breast core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1807898,right breast biopsy.,right breast lump biopsy.,received 4 grey white core measures 0.5 to 1cm. entire tissue processed.,section show linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords small cluster consisting of cells having round to elongated dark nuclei inconspicuous cytoplasm. few cells show intranuclear inclusion. mitotic figures 8 9 10hpf. stroma show desmoplastic changes.,right breast lump biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1807911,right breast lump possibility of carcinoma.,right breast lump biopsy.,received multiple linear core measures 0.5 to 1.5cm. entire tissue processed.,section show linear cores of breast parenchyma harboring a neoplastic lesion arranged in nests and trabecular consisting of cells having round to oval dark nuclei prominent nucleoli and moderate cytoplasm. mitotic figures 2 3 hpf. stroma shows extensive hyalinisation.,right breast lump biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1807914,carcinoma left breast.,a) wide local excision of the left breast lump. b) left sentinel biopsy.,a) received a wild lesion excision specimen 8.2x6x3.1cm.skin ellipse measures 5x4cm. no scar. tumor 1.2x1.5x1.4cm. resected margins:superior margin : 3.5cm.inferior margin : 2cm. medial margin : 0.7cm.lateral margin : 3.7cm.deep margin : 1.1cm.b) received 3 fibrofatty tissue :1) blue + hot node measures 3x1.6x1.2cm. cut surface shows a lymphnodes 1.6x0.7cm. cut surface fibro invasion. 2) fibrofatty tissue measures 1.1x0.9x0.6cm. single lymphnode measures 0.9x0.2 cmcut surface grey brown. 3) fibrofatty tissue measures 3.5x2.5x0.1. cut surface 1 lymphnodes measures 2.5x2cm.,a) breast conservative surgery left sidetumor is composed of pleomorphic cells with pleomorphic vesicular nucleus and scanty cytoplasm. these clumps and groups of cells are surrounded by mucinous areas. there is no evidence of ductal carcinoma in situ. modified br score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 .............. 7 9 ...............nuclear grade 2.lymphovascular invasion not identified. perineural invasion not identified. resected margins : superior margin : free of tumor. inferior margin : free of tumor. medial margin : free of tumor. lateral margin : free of tumor. deep margin : free of tumor. lymph nodes :sentinel lymph nodes (frozen) : 3 nodes. no deposits of tumor (0 3)further lymph node on paraffin section : 2 nodes. no deposits of tumor (0 2)summary : left breast conservative surgery wide local excision. histological type : mucinous carcinoma. tumor maximum dimension measures 1.5x1.4x1.2cm. invasive component measures 1.5cm. ductal carcinoma in situ not identified.lymphovascular invasion not identified. perineural invasion not identified. resected margins all are free of tumor. lymph nodes : sentinel lymph nodes (frozen) :3 nodes. no deposits of tumor (0 3) routine paraffin section : 2 nodes. no deposits of tumor (0 2)total nodes : 5. all are free of tumor. (0 5)pathological grade : pt1n0.,left breast conservative surgery wide local excisionmucinous carcinomagrade 2all lymph nodes are free of tumour
MR1807954,left breast lump.,biopsy from left breast lump.,received grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section show linear cores of breast tissue showing invasive sheets and nests of dysplastic ductal cells showing moderate anisonucleosis hyperchromatin nuclei and prominent nuclei. the intervening stroma show moderate dysplasia. occasional focus show comedo necrosis.,left breast lump biopsy :invasive carcinoma of ductal origin nst left breast. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1807989,lump left breast.,left breast biopsy.,received 4 grey white linear cores measures 0.2 to 0.5cm. entire tissue processed.,sections show linear cores cores of breast parenchyma harboring an infiltrative neoplasm arranged in nests sheets trabecular and acini of neoplastic cells exhibiting increased n c ratio pleomorphic hyperchromatic nuclei prominent nucleoli and moderate amount of pale eosinophilic cytoplasm. extensive areas of necrosis present. few lymphoid aggregates present in the intervening dense fibrocollagenous connective tissue.,left breast biopsy :invasive carcinoma breast nst grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1807998,right breast lump carcinoma breast.,right breast lump biopsy.,received 3 grey white grey brown linear cores measures 0.8 to 1.2cm. entire tissue processed.,section show linear cores of breast tissue one of them showing tiny focus of dysplastic ductal cells arranged in nests showing moderate anisonucleosis hyperchromatic nuclei and prominent nucleoli. the intervening stroma i desmoplastic and foci of necrosis seen. adjacent cores show benign cluster cells.,right breast lump biopsy :suggestive of ductal carcinoma in situ with suspicious focus of invasion. suggest repeat biopsy to look for invasion.
MR1808021,right breast lump.,right breast lump biopsy.,received 3 linear cores each measures 0.1 cm. entire tissue processed.,sections show linear cores cores of breast parenchyma harboring an infiltrative neoplasm arranged in nests and cords of cells exbiting increased n c ratio pleomorphic hyperchromatic nuclei occasional prominent nucleoli and scant to moderate amount of pale eosinophilic cytoplasm. few bizzare cells noted. the intervening stroma shows presence of dense fibrocollagenous correlative tissue.,right breast lump biopsy :invasive carcinoma breast nst grade 3.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1808032,left breast lump carcinoma breast.,left breast biopsy.,received 4 linear cores grey white soft tissue bits measures 1.2 to 1.5cm. entire tissue bits.,section shows linear cores of breast tissue composed of neoplastic lesion showing invasive sheets and nests of round to oval cells showing moderate pleomorphism hyperchromatic nuclei mitotc activity is brisk. focus of comedo necrosis seen. the intervening stroma is desmoplastic.,left breast biopsy :invasive carcinoma of ductal origin.nst grade iii.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 focus of necrosis seen.
MR1808080,left breast lesion.,left breast biopsy.,received 4 grey white linear cores measures 1.2 to 1.5cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in cords nests and few tubules. the cells show moderate granular eosinophilic cytoplasm hyperchromatic nuclei with moderate pleomorphism and prominent nucleoli. mitosis is increased stroma is desmoplastic. areas necrosis present.,left breast core biopsy :invasive carcinoma (nst) grade ii modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1808096,left breast lump carcinoma breast.,left breast lump biopsy.,received grey white linear cores measures 0.2 to 0.5cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in sheets and nests. the cells show moderate cytoplasm and increased mitotic cores of ductal carcinoma in situ prominent stroma is desmoplastic.,left breast biopsy :invasive carcinoma nst grade iimodified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 7 9
MR1808102,left breast lump carcinoma breast.,left breast lump biopsy.,received 3 linear cores grey white to grey brown soft tissue bits measures 1.5 to 2cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in nests and cords. the cells show moderate eosinophilic cytoplasm hyperchromatic nuclei with moderate pleomorphism and increased mitosis.,left breast lump biopsy :invasive carcinoma nst grade ii.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1808105,left carcinoma breast,a) left axillary sentinel lymph node biopsyb) wide local excision breast lump.c) left axillary dissection.,a) received multiple fibrofatty tissue measures 4x3x3cmlargest lymph nodes measures 1.5x1x1cmcut surface fatty infiltration.b) received skin covered mass measures 6.5x5x3cmskin ellipse measures 3x0.5cmcut surface ill defined grey white measures 1.5x1x1cmdistance from margins:superior margin : 1cminferior margin : 0.8cmmedial margins : 1.5cmlateral margins : 1.2cmdeep margins : 1.3cmc) received fibrofatty tissue measures 7x6x4cmlargest lymph node measures 0.7x0.6x0.5cm.,a) left axillary sentinel lymph node3 nodes no metastatic deposits of tumorb) wide local excision breast lump:the tumor is harboring viable tumor consisting of pleomorphic cells with hyperchromatic nuclei and eosinophilic cytoplasmmodified bloom richardson score is 8 9tubule formation 3nuclear pleomorphism 2mitotic figures 3nuclear grade iiiinvasive ductal carcinoma with ductal carcinoma in situ with comedonecrosis and solid type.lymphovascular invasion not identifiedperineural invasion not identified.all resected margins are free of tumor.c) left axillary dissection.10 nodes no deposit of tumor,wide local excision left breast lumpectomy:maximum dimension of tumor measures 1.5x1x1cm.viable invasive carcinoma measures 1cm. nuclear grade iii.ductal carcinoma in situ measures 0.5cm with comedonecrosis.lymphovascular invasion not identified.resected margins free of tumor.lymph nodes:sentinel lymph nodes 3 lymph nodes no deposit of tumor.axillary lymph nodes 10 nodes no deposit of tumor.total nodes 13 nodes no deposits of tumor.pathological grade : ypt1no.
MR1808113,left breast lump carcinoma breast.,left breast lump biopsy.,received 4 linear core grey white to grey brown soft tissue bits measures 1.2 to 1.5cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in sheets and nests with moderate cytoplasm hyperchromatic nuclei with moderate pleomorphism and increased mitosis. few ducts show comedo type ductal carcinoma in situ. areas necrosis noted stroma is desmoplastic with moderate lymphoplasmacytic infiltrate ductal carcinoma in situ with comedo necrosis seen.,left breast core biopsy :invasive carcinoma nst grade iii.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR1808168,left breast lump carcinoma breast.,left breast lesion biopsy.,received grey white to grey yellow 4 linear cores measures 1 to 1.2cm. entire tissue processed.,section shows cores of breast parenchyma showing lymphoplasmacytic infiltrate histiocytes and epithelioid like cells. focal area of necrosis seen. a few atypical cells seen.,left breast lesion biopsy :granulomatous inflammation .in view of few atypical cells suggest follow up repeat biopsy
MR1808194,carcinoma left breast post nact,a) left axillary lymph nodes dissection.b) left modified radical masectomy post nact.,a) received multiple fibrofatty tissue measures 5x4x3cm.largest lymphnode measures 2x1x1cm. cut section shows fatty infiltration.b) received in : formalin procedure : modified radical mastectomy post nact. laterality : lefttotal dimensions : medial to lateral :16cm superficial to deep :4cm superior to inferior : 11cmskin ellipse :13x6.5cm skin shows scar measures 3cmnipple :unremarkable scar surgical defect : notumor : total lumpectomy bed measures 5.5x3.6cm tumor size : 1.6x1.5x1cmm location of tumor :upper outer quadrantmargins of tumor : ill defined deep margin : 1.2cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail : 8x3x3cmsize of largest node : 1x1x0.5cm,b) section studied shows breast parenchyma harboring an infiltrating lesion arranged in sheets and nests. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. stroma is desmoplastic with areas of hemorrhage and necrosis.,a) left axillary lymph nodes dissection:two of the isolated eight lymph nodes are show metastatic deposits of tumor out of eight nodes (2 8)extranodal extension is seenb) left modified radical mastectomy post nact:histological type:residual viable invasive ductal carcinoma.grade :2tumor component maximum dimension 1.6cm.invasive component measures 1.0cm.ductal carcinoma in situ measures 0.6cm.modified bloom richardson score is 7 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2ductal carcinoma in situ solid and comedonecrosis pattern is seenlymphovascular invasion is identified.perineural invasion is not seen.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes 6 lymph nodes metastasis 0(0 6)pathological stage ypt1n1summary:residual viable invasive ductal carcinoma left breasttumor grade 2lymph nodes status 2 14.(sentinel lymph nodes 2 nodes show metastatic deposits of tumor out of 8 nodesaxillary nodes 6 nodes shows no metastatic deposit of tumor.)total nodes 2 nodes show metastatic deposits of tumor out of 14 nodes perinodal spread present.
MR1808203,left breast lesion residual.,biopsy from left breast lesion.,received 7 grey white linear core measures 0.8 to 1.2cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an invasive neoplasm arranged in solid nests vague glandular pattern. the lesional cells are polygonal with abundant eosinophilic cytoplasm round hyperchromatic nucleus few showing prominent nucleoli and intranuclear inclusion. moderate nuclear pleomorphism noted. stroma show extensive desmoplasia and show lymphoplasmacytic infiltrates. area of calcification and necrosis noted.,biopsy from left breast lesion. invasive carcinoma ductal origin nst. nuclear grade iii.
MR1808222,right breast lump possibilities of carcinoma breast.,right breast lump biopsy.,received 4 linear grey core each measures 0.4 to 1cm. entire tissue processed.,section shows multiple fragments of breast parenchyma with a infiltratory neoplasm arranged in sheets nest and few tubules. the cells are round to oval nuclei scant to moderate clear cytoplasm hyperchromatic nuclei mild pleomorphism is seen. background shows desmoplasia intervening stroma shows lymphoplasmacytes. mitotic seen 4 5 10hpf. foci of ductal carcinoma in situ with solid pattern and comedo necrosis seen.,right breast lump biopsy :invasive ductal carcinoma grade iimodified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 1 7 9 with ductal carcinoma in situ with comedonecrosis solid pattern.
MR1808228,right breast lump carcinoma breast.,right breast lump biopsy.,received 4 grey white firm soft tissue cores 0.2 to 0.4cm. entire tissue bits.,section shows linear cores of breast parenchyma harboring an invasive neoplasm arranged in cords and tubules. the cells have round nucleus inconspicuous nucleoli and moderate cytoplasm. extensive areas of hyalinisation.,right breast lump biopsy :invasive ductal carcinoma grade ii.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1808230,left breast lump carcinoma breast.,left breast lump biopsy.,received 5 grey white to grey brown linear cores measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an invasive neoplasm arranged in lobules and cords. the tumor cells are large with round to irregular pleomorphic nucleus dispersed chromatin prominent nucleoli and moderate cytoplasm. surrounding stroma shows scattered lymphocytes and plasma cells.,left breast lump biopsy. :invasive carcinoma nos nuclear grade ii.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1808239,cerebellar metastasis in known case of carcinoma breast.,cerebellar lesion.,received grey white to grey brown soft tissue bits altogether measures 5.5 x 3.5 x 1.5cm. entire tissue processed.,sections from cerebellar sol shows tumor tissue arranged in diffuse sheets cords and trabecular vague acinar pattern. tumor cells show high n c ratio moderate eosinophilic cytoplasm pleomorphic round to oval vesicular to hyperchromatic nuclei and prominent nucleoli. few nuclei show intranuclear inclusions. areas of necrosis and congested blood vessels noted. normal cerebellar tissue not seen.,cerebellar lesion biopsy. :suggestive of metastatic deposits of invasive ductal lobular carcinoma. suggest ihc.
MR1808286,left breast mass carcinoma breast.,left breast mass.,received multiple grey white linear cores measures 2 to 2.5cm. entire tissue processed.,sections shows linear cores of breast parenchyma infiltrated by a neoplasm arranged in abortive tubules and cords. the cells have round to oval hyperchromatic nucleus and moderate cytoplasm. the stroma is desmoplastic with myxohyaline change. mitoses is discerned. lymphovascular invasion is seen.,left breast mass:invasive ductal carcinoma grade ii.modified bloom richardson score is 6 9.tubule formation 2nuclear pleomorphism 2mitotic activity 2 6 9
MR1808296,left breast lump possibility of carcinoma breast.,left breast lump biopsy.,received 4 grey white to grey yellow linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets and nests. the lesiona cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. the cells exhibit moderate nuclear pleomorphism. stroma is desmoplastic. areas of necrosis seen. mitosis 4 5 10hpf.,left breast lump biopsy :invasion ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1808304,left breast lump possibilities of carcinoma breast.,left breast lump biospy.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in nests cords and few tubules. the lesional cells are round to oval having hyperchromatic nuclei and moderate cytoplasm cells exhibit moderate nuclear pleomorphism. stroma shows desmoplasia. mitotic 3 4 10hpf.,left breast lump biopsy :invasive ductal carcinoma grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1808307,right breast mass carcinoma breast.,biopsy from right breast mass.,received 4 cores grey white soft tissue bits each measures 0.6 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating neoplasm arranged in cords and inclusion file pattern. the cells have round to angulated hyperchromatic nucleus and moderate cytoplasm.,right breast mass biopsy :suggestive of invasive lobular carcinoma nuclear grade 2
MR1808310,right breast lump possibilities of carcinoma breast.,right breast lump biopsy.,received 4 linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in nests sheets of tubules. the lesional cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. cells exhibit moderate nuclear pleomorphism.,right breast lump biopsy :invasive ductal carcinoma grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1808382,lump in left breast carcinoma left breast,left breast lump biopsy.,received multiple soft tissue bits altogether measures 1x0.8 x 0.6cm. entire tissue processed.,section show linear cores of breast parenchyma harboring an infiltrating neoplasm arranged in sheets and cords. the cells have pleomorphic round cytoplasm. bizarre nuclear forms noted. also seen is a fragment of tissue lined by hyperplastic squamous epithelium with no atypia.,left breast lump biopsy : invasive carcinoma (nst) grade 3modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1808385,left breast lump possibilities of carcinoma breast.,left breast lump biopsy.,received 3 grey white to grey yellow soft tissue bits cores measures 0.5 to 0.6cm. entire tissue processed.,section shows linear cores of fibrofatty tissue infiltrated by neoplastic cells arranged in cords nests and tubules. the neoplastic cells are large harboring round nucleus dispersed chromatin and moderate cytoplasm.,left breast lump biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1808387,right breast mass carcinoma breast.,biopsy from right breast.,received 5 linear cores grey white soft tissue bits 0.5 to 1cm. entire tissue processed.,section shows linear cores of fibrofatty tissue infiltrates by neoplastic cells arranged in sheets and nests. lesional cells are large round hyperchromatic nucleus porminent nucleoli and moderate cytoplasm. areas of focal necrosis seen.,right breast mass biopsy :invasive carcinoma with focal papillary features.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1808423,left breast lump carcinoma breast.,left breast lump.,received 5 grey white linear cores measures 0.6 0.8 cm.,section shows linear areas of breast parenchyma infiltrated by neoplastic cells arranged in cords and sheets. the cells have round nucleus dispersed chromatin inconspicuous nucleoli and moderate cytoplasm.,left breast lump :invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1808435,left breast lump carcinoma breast.,left breast lump biopsy.,received 4 grey white linear cores 0.8 to 0.5cm. entire tissue processed.,section from breast parenchyma showing infiltrative lesion arranged in nest sheets and tubules. the lesion cells are consisting of round to oval moderately pleomorphic hyperchromatic nuclei of eosinophilic cytoplasm. mitotic activity discerned.mild lymphocytic infiltrate seen.,left breast lump biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1808439,left breast lump possibility of carcinoma breast.,left breast lump biopsy.,received 3 grey white linear cores measures 0.5 0.7cm. entire tissue processed.,the section shows tumor composed of pleomorphic cells with hyperchromatic nucleus. in some areas cells are arranged in clumps and sheets and in other areas in papillary structures with fibrovascular cores lined with pleomorphism cells. marked degree of nuclear pleomorphism is present and mitotic figures are 8 10 hpf nuclear grade ii. necrotic areas re present.,left breast lump biopsy.invasive carcinoma with papillary carcinoma.
MR1808440,left chest wall lesion post modified radical mastectomy 2 years agocarcinoma left breast recurrent.,biopsy from left chest wall lesion.,received multiple grey white linear cores measures 0.3 0.4cm. entire tissue processed.,tiny fragments of collagenous tissue with extensive necrosis and few small aggregates of round cells with dense nuclei. numerous crush artifacts seen.,biopsy from left chest wall lesion:necrotic tissue with focal small aggregates of round cells.tissue inadequate for conclusive opinion.
MR1808465,right breast lump possibility of carcinoma breast.,biopsy from right breast lump,received 5 grey white linear cores measures 0.3 0.9cm. entire tissue processed.,the section shows tumor composed of pleomorphic cells with hyperchromatic nucleus and scanty cytoplasm. tubular formation less than 10 score3 nuclear pleomorphism score2 mitotic figures score2modified bloom richardson score is 7 9 grade ii.few ducts show ductal carcinoma in situ.,biopsy from right breast lump:invasive ductal carcinoma grade ii.few ducts show ductal carcinoma in situ.
MR1808543,carcinoma left breast post lumpectomy.,left modified radical mastectomy.,laterality : left breast.total dimensions :medial lateral : 21cm superficial deep : 5cm superior inferior : 14cmskin ellipse : 16x8cmnipple : normal scar surgical defect : 4cm from lateral to nipple areola.tumor : not identified.tumor size : firm area desmoplasia measures 3x1x1cm identified.deep margin : 0.8cmmuscle : absent.adjacent breast : fibrofatty tissue.axillary tail : 8x8x2cm,section studied shows fibrocollagenous tissue with extensive areas of desmoplasia and inflammatory granulation tissue comprising of lymphomononuclear cell infiltrates histiocytes macrophages and proliferating blood vessels.no evidence of atypia noted.,left modified radical mastectomy post lumpectomy.tumor bed : no residual viable tumor.posterior resection margin is unremarkable.nipple and areola : unremarkable.lymph nodes: 17 lymph nodes metastasis: 0(0 17)pathological stage :yptxn0summary:no evidence of malignancy left breastlymphnode status 0 17.
MR1808563,a) left breast lump carcinoma breast. b) liver lesion metastatic.,a) left breast lump biopsy. b) liver lesion biopsy.,a) received five linear core of soft tissue bits measures 1 to 1.5 cm. entire tissue processed. b) received six linear cores measures 1.5 to 2 cm. entire tissue processed.,a) section shows linear cores of breast parenchyma harboring infiltrating lesion arranged in cords nests and tubules. the lesional cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. stroma is sclerotic cells exhibit moderate nuclear pleomorphism. mitosis 2 3 10hpf. b) section show multiple cores of linear parenchyma harboring infiltrating lesion arranged in sheets cords and tubules. the lesional cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. intervening stroma shows sclerosis.,a) left breast lump biopsy : invasive ductal carcinoma grade ii. modified bloom richardson score is 6 9 tubule formation : 3 nuclear pleomorphism : 2 mitotic figures : 1 6 9 b) liver biopsy : suggestive of metastatic carcinoma most probably from breast.
MR1808567,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received 5 grey white linear cores measures each 1 cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in nests cords and vague tubules. individual cells are round to oval with hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism mitosis 3 4 10 hpf.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1808584,right breast lump possibilities of carcinoma breast.,right breast lump biopsy.,received 3 grey white to grey brown linear cores measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in sheets nests cords and tubules. the cells have round nucleus inconspicuous nucleoli and moderate cytoplasm. mitosis is discerned. focal areas of necrosis is noted.,right breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 areas of necrosis seen.
MR1808595,birads in lesion right breast.,a) right breast wide local excision. b) left breast post lumpectomy. c) revised deep margin of right breast lump d) left axillary dissection.,a) right breast wide local excision : received soft tissue mass measures 6x4.5x2cm. cutsurface shows cystic lesion measures 1.2cm in diameter. grossly no solid area identified. distance from margins :superior margin : 1 cm.inferior margin : 1.2 cm.medial margin : 1 cm.lateral margin : 1 cm.deep margin : 1 cm.b) left breast post lumpectomy : received singly soft tissue mass measures 7x5x2cm. cutsurface identified firm grey white lesion measuring 1.3x1x1cm. distance from margins :superior margin : 1 cm.inferior margin : 1.5 cm.medial margin : 1 cm.lateral margin : 1 cm.deep margin : 1 cm.c) revised deep margin of right lump (inked surface away from lump) : received fibrofatty tissue measures 2x1.2x0.6cm one surface inked. d) left axillary dissection : received fibrofatty tissue 5.5x4.5x3.5cm. largest lymphnode measures 0.8x0.6x0.4cm. cutsurface grey white.,a) right breast wide local excision : section studied show breast parenchyma with dilated ducts of varying size few having secretions in the lumen. they are lined by inner outer myoepithelial layer. the stroma shows hyalinisation and occasional lymphomononuclear cell infiltrates. b) left breast post lumpectomy : sections studied show breast parenchyma harboring an infiltrating lesion arranged in nests tubules and sheets the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucloli. mitotic figures are discerned. stroma is desmoplastic with areas of hemorrhage necrosis and focal fibrosis.,a) right breast wide local excision :atypical ductal hyperplasia with few foci exhibiting flat epithelial atypia and usual ductal hyperplasia. no evidence of malignancy in the material submitted. deep margin shows features of adh.all other margins (superior inferior medial and lateral) are free of tumor. b) left breast wide local excision post chemotherapy. residual invasive ductal carcinoma grade. modified br score is 6 9tubule formation : 2 nuclear pleomorphism : 2mitotic figures : 2 ............ 6 9 .............tumor measures 1.3 cm in greatest dimension. invasive component measures 1.0cm. ductal carcinoma in situ measures 0.3cm. solid and cribriform pattern low grade. lymphovascular invasion and perineural invasion are not seen. all margins of resection (superior inferior medial lateral and deep) are free of tumor. c) revised deep margin of right breast lump : free of tumor. d) left axillary dissection. isolated all eleven lymphnodes are free of tumor. 0 11.summary : left breast : post chemotherapy. residual invasive ductal carcinoma grade 2.tumor measuring 1.3cm in greatest dimension. lymphnodes : 0 11 all resected margin are free of tumor. pathological grade : ypt1pn0.right breast :atypical ductal hyperplasia.all margins including revised deep margins are unremarkable.
MR1808603,carcinoma left breast.,left modified radical mastectomy.,received 11 blocks labelled as s. 807 a e 18 s 807 f i s 807 k l 18received 8 slides labelled as s8.7 a b e f g h i e.received one specimen labelled as sandya rani.procedure : received already grossed in multiple bits.received in : formalinprocedure : modified radical mastectomy laterality : left total dimensions : medial to lateral :16cm superficial to deep : 4.5cm superior to inferior :13cmskin ellipse :10x3cm nipple unremarkable :normalscar surgical defect :not seentumor : singletumor size : 2.5x2x2cm location of tumor : lower inner quadrantmargins of tumor : ill defined deep margin : 1 cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail :multiple bits measures 6x4x3 cm,section studied shows breast parenchyma harboring foci of invasive neoplasm with extensive ductal carcinoma in situ (cribriform comedo and micropapillary pattern). the cells show moderate pleomorphism with moderate amount of eosinophilic cytoplasm pleomorphic ovoid nucleus coarse chromatin and prominent nucleoli. mitotic figures are 8 10 hpf. stroma shows many congested blood vessels and inflammatory infiltrated comprising of lymphocytes and plasma cells. foci of microcalcification noted.deep resected margin free of tumor.nipple and areola unremarkable and free of tumor.lymph nodes:slides labelled as s.807 18 g h show 14 lymph nodeslymph nodes none of these show metastatic deposits of tumor (0 4).grossed specimen shows 4 lymph nodes.none show metastatic deposits of tumor (0 4).,modified radical mastectomyhistologic type:infiltrating ductal carcinoma with extensive ductal carcinoma in situ.grade:iitumor measures 3cm in maximum dimension invasive component measures 0.5cm. (small multiple foci of invasion seen).ductal carcinoma in situ measures 90 of tumormodified br score is 5 9tubule formation: 2 nuclear pleomorphism: 2mitotic figures: 1ductal carcinoma in situ 2.5cm.lymphovascular invasion not seen.perineural invasion not seen. posterior resection margin is free of tumor. nipple and areola is unremarkablelymph nodes: 18 lymph nodes metastatic deposits : 0 (0 18).summary:infiltrating ductal carcinoma with extensive ductal carcinoma in situ left breasttumor grade:iilymph node status: no metastatic deposits of tumor seen.
MR1808620,right breast lump carcinoma breast.,right breast lump biopsy.,received 5 grey whit linear cores measures 0.8 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a neoplasm arranged in tubules cords of sheets. the cells have round to oval hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm. mitotic is discerned.,right breast lump biopsy :invasive carcinoma of ductal origin nst grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1808655,left breast mass.,left breast mass biopsy.,received 5 grey linear core measures 1 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in cords. the lesional cells have pleomorphic round to angulated hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm .mitotis is discerned.,left breast mass biopsy :suggestive of invasive ductal carcinoma grade ii.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 7 7 9
MR1808665,right breast lump possibilities of carcinoma breast.,right breast lump biopsy.,received 4 linear core of grey white to grey yellow soft tissue bits measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in lobules nests tubules with area of necrosis. the lesional cells are large with round nucleus dispersed chromatin prominent nucleoli and moderate cytoplasm. mitosis discerned.,invasive carcinoma nst grade 2 .modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1808678,left breast lump carcinoma breast.,left breast lump biopsy.,received 3 linear core of grey white to grey brown soft tissue bits measures 0.5 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in tubules and cords. the lesional cells have round nucleus inconspicuous nucleoli and moderate cytoplasm. surrounding stroma show hyalinization. mitotis is discerned.,left breast lump biopsy :invasive ductal carcinoma grade ii.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1808710,right breast lump possibilities of carcinoma breast.,right breast lump biopsy.,received 3 grey linear core measures 1 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in cords. the cells and have round to angulated hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm mitotic is discerned.,right breast lump biopsy :invasive carcinoma with lobular features grade ii.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1808734,right axillary node.,right axillary node biopsy.,received 4 grey linear core measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast tissue harboring a lesion arranged in islands cords and ducts case of neoplastic cells having round to oval pleomorphic dark nuclei inconspicuous nucleoli and moderate eosinophilic cytoplasm. also seen areas with ductal carcinoma in situ cribriform and comedonecrosis pattern.stroma shows desmoplasia and lymphoplasmacytic infiltrates.,right axillary node biopsy :no lymphoid tissue identified. breast tissue seen. invasive ductal carcinoma grade 2.(with ductal carcinoma in situ cribriform solid pattern and comedonecrosis). modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1808779,right breast lump.,right breast lump biopsy.,received 5 grey white linear cores of measures 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in cords and sheets. the tumor cells have round to oval nucleus dispersed chromatin inauspicious nucleoli and moderate cytoplasm. lots of crush artifact and desmoplasia.,right breast lump biopsy :suggestive of ductal carcinoma nuclear grade 2.note : as there is lots of desmoplasia and crush artifact if is advisable to repeat biopsy for immunohistiochemistry.
MR1808823,carcinoma right breast.,right breast lump biopsy.,received 4 grey white linear cores measures 0.5 1 cm,sections shows cores of tissue showing extensive necrosis with no viable cells are seen.,right breast lump biopsy :shows only extensive necrosis. no viable cells are seen.suggest repeat biopsy if clinically indicated.
MR1808849,left breast lump possibilities of carcinoma breast.,left breast core biopsy.,received multiple grey white to grey brown linear cores measures 0.2 to 1cm. entire tissue processed.,section shows breast parenchyma harboring infiltrating lesion arranged in nests and sheets. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. intervening stroma sheets lymphoplasmacytic infiltrate. mitosis 5 6 10hpf.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1808869,left breast lump carcinoma breast.,left breast lump biopsy.,received 4 grey white to linear cores measures 1.5 to 2cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in nests and cords composed of cells with moderate eosinophilic cytoplasm hyperchromatic nuclei with moderate pleomorphism .stroma is desmoplastic with hyalinization.,biopsy from left breast lump. :invasive carcinoma nst grade ii. modified bloom richardson score is7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1808917,case of right breast carcinoma,a) right breast wide excisionb) revised base(muscle)c)hot noded) blue + hot nodee) right axillary dissection.,a) received lumpectomy specimen measures 7x6x5.5cmskin ellipse measures 4.5x1.5cm on serial section lesion identified ( infiltrative grey white lesion) measures 3.2x2.6x1.9cmdistance from margins: superior margin : 1.3cminferior margin : 1.5cmmedial margin : 2.5cmlateral margin : 1.6cmdeep margin : 1.8cmb) received small soft tissue bits with thickening on one side. grossly no tumor seenstitched surface is inked.c)received fibrofatty tissue measures 2x1.3x2.8cm. largest measures 1.4x1x0.7cm. cut surface unremarkable.d) received fibrofatty tissue measures 2.5x1x0.8cm largest lymph node measures 1.3x1x0.6cmcut surface fatty infiltrate.e) received fibrofatty tissue measures 8.5x8x3cm.largest lymph node measures 2.5x2x1cmcut surface grey white (involved).,a) right breast wide excision:tumor is composed of pleomorphic cells with hyperchromatic nucleus with scanty cytoplasm. the tumor present in clumps groups and sheets of cells tubular formation less than 10 (3) mitotic figures(2) nuclear pleomorphism (2)modified bloom richardson score is 7 9 grade iiductal carcinoma in situ not presentlymphovascular invasion is presentperineural invasion is presentresected margins: superior margin: free of tumor.inferior margin :free of tumor.medial margin :free of tumor.lateral margin :free of tumor.all resected margins are free of tumorb) deep margin:the section muscle bundle free of tumor.c) hot node : sentinel node dissected 2 nodes one node shows metastatic deposit of tumor out of 2 nodes in paraffin section.(1 2)d) blue and hot node: sentinel node two nodes detected one node shows metastatic deposit of tumor out of 2 nodes.(1 2)e) right axillary dissection:7 nodes show metastatic deposits of tumor out of 17 nodes.(7 17)perinodal spread present..,conservative breast surgery wide local excision:invasive ductal carcinomamaximum dimension of tumor is measures 3.2x2.6x1.9cm.grade iiductal carcinoma in situ not present.lymphovascular invasion is present.perineural invasion is present.all resected margins are free of tumor.deep resected margin muscle bundle free of tumor.lymph nodes:sentinel lymph node and axillary lymph nodes 9 nodes show metastatic deposit of tumor out of 21 nodes(9 21)pathological stage : pt2n2.
MR1808949,carcinoma left breast.,a) hot and blue node.b) not hot and not blue node.c) left modified radical mastectomy.,a) 2 lymph nodes largest measures 1.8x1x1cm. cut surface is unremarkable fatty infiltration.b) received 1 lymph node measures 1.2x1x1cm. cut surface is unremarkable.c) received in : 10 nbf.procedure : left modified radical mastectomy.laterality : left.total dimensions : medial to lateral 16cm superficial to deep 6cm superior to inferior 15cm.skin ellipse : 12x7cm. nipple : unremarkable. scar surgical defect : absent.tumor : single.tumor size : 2.5x1.5x1.5cm.location of tumor : retroareolar.margins of tumor : illdefined.deep margin : 1.5cm. muscle : absent.adjacent breast : fibrofatty tissue. axillary tail : 12x4x2cm.size of largest node : 1.8x1.5x0.5cm. cut surface involved.,sections show tumor infiltrating breast parenchyma in the form of sheets nests and cords composed of polygonal cells with marked pleomorphism high n:c ratio vesicular nucleus with prominent nucleolus and scant cytoplasm. mitosis are 10 12 10hpf. necrosis is seen. small focus of ductal carcinoma in situ with cribriform and comedo pattern seen.,a) hot and blue node:2 lymph nodes isolated and are free of tumor.(0 2)b) not hot and not blue node:1 lymph nodes isolated and is free of tumor.(0 1)c) left modified radical mastectomy.histological type: invasive ductal carcinoma nst.grade: 3tumor measures maximum dimension 2.5cm.invasive component measures 2.3cm.ductal carcinoma in situ measures 0.2cm.modified br score is 8 9tubule formation: 3nuclear pleomorphism: 2mitotic figures: 3ductal carcinoma in situ is comedo and cribriform type.lymphovascular invasion is not identified.perineural invasion is not identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes 10 lymph nodes metastasis 0 (0 10).pathological stage: pt2n0summary:invasive ductal carcinoma nst left breast.tumor grade: 3lymph nodes : 0 13sentinel lymph nodes 3 nodes. no deposits of tumor.modified radical mastectomy specimen 10 nodes.no metastatic deposit of tumor.
MR1808957,right breast lump possibilities of carcinoma breast.,right breast lump.,received 2 grey white linear cores 1cm. each.,section shows tiny linear cores of breast parenchyma harboring ductal carcinoma in situ (solid pattern) . foci of invasion is not seen.,right breast lump : suggestive of ductal carcinoma in situ low grade. no invasive is seen.
MR1808975,left breast lump possibilities of carcinoma breast.,left breast lump biopsy.,received 4 grey brown linear cores measures 0.5 to 1 cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy :invasive carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1809028,case of right breast carcinoma,right modified radical mastectomy post nact.,received in : formalin procedure : modified radical mastectomy post nact laterality : righttotal dimensions : medial to lateral :17cm superficial to deep : 6cm superior to inferior : 17cmskin ellipse :13x10.5cmnipple :normal scar surgical defect : not seentumor : single tumor size : 1x1x0.5cm location of tumor : upper central quadrantmargins of tumor : ili defined with extensive desmoplasia deep margin : 1.5cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail : 14x7cmsize of largest node :1x1x0.5cm cut surface grey brown,tumor bed:multiple section show dense hyalinisation with atrophic ducts. surrounding ducts show adenosis and fibrocystic disease,right modified radical mastectomy post nact:histological type: no evidence of residual viable tumor present.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes 10 lymph nodes no metastatic deposits of tumor.pathological state : yptxn0no residual viable tumor right breastlymph node status :10 nodes no metastatic deposit of tumor.
MR1809054,left axillary lymph node deposit.,left axillary lymph node.,received 5 grey white linear cores measures 0.8 to 1.4cm. entire tissue processed.,section shows linear cores of tissue infiltrated by a neoplastic lesion arranged in islands nests and cords of atypical cells having round to oval pleomorphic dark nuclei some with prominent nucleoli and moderate eosinophilic cytoplasm. mitotic figures noted. stroma shows desmoplasia and lymphoplasmacytic infiltrate.,left axillary lymphnode biopsy :metastatic carcinoma possibly from breast.
MR1809056,left breast lump birods iv b.,left breast lump biopsy.,received 5 linear core measures 0.8 to 1.2cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in cords and tubules. the cells have round nucleus dispersed chromatin inconspicuous nucleoli and moderate cytoplasm. surrounding stroma shows desmoplasia. mitosis is discerned.,left breast lump biopsy :invasive ductal carcinoma grade ii.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1809075,right breast lump possibilities of carcinoma breast.,right breast lump biopsy.,received 4 grey white to grey brown linear cores measures 1 to 1.5cm. entire tissue processed.,section show linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in lobules and acini with large areas of mucin pools. the tumor cells have round nucleus hyperchromatic nucleus and moderate cytoplasm.,right breast lump biopsy. :invasive carcinoma with mucinous features. nuclear grade 1.modified bloom richardson score is 5 9tubule formation : 3nuclear pleomorphism : 1mitotic figures : 1 5 9
MR1809103,left breast lump carcinoma breast,left breast lump core biopsy.,received 4 grey white linear cores each measures 1.5cm. entire tissue processed.,section shows cores breast tissue infiltrated by tumor cells in diffuse sheets and nests. individual tumor cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1809121,hard lump in right carcinoma right breast. fnac suggestive of ductal cell carcinoma.,right breast lump biopsy.,received 4 linear cores of grey white to grey brown measures 1 to 1.5cm. entire tissue processed.,section shows multiple cords of breast parenchyma harboring infiltrating lesion arranged in nests tubules cords and sheets. the lesional cells are round to oval having hyperchromatic nuclei moderate eosinophilic cytoplasm. cells exhibit moderate nuclear pleomorphism mitosis 3 4 10hpf. intervening stroma sheets lymphocytic infiltrate.,right breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1809156,right breast lump birods iv lesion.,right breast lump biopsy.,received 4 grey white linear cores each measures 1.5 x 0.3 x 0.2cm. entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged in glandular pattern. the lining epithelial cells are cuboidal have vesicular nucleai conspicuous nucleoli and moderate cytoplasm. the intervening stroma is elastotic.,right breast lump biopsy :invasive ductal carcinoma.grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1809179,left breast carcinoma with post lumpectomy.,left breast left modified radical mastectomy(post lumpectomy).,received in : formalinprocedure : left modified radical mastectomy post lumpectomy.laterality : left breast.total dimensions :medial lateral : 17 cm superficial deep : 3 cm superior inferior : 13 cmskin ellipse : 13x6 cm shows an ulceration measures 2x1.5 cmnipple : unremarkabletumor : singlescar surgical defect : surgical defect in lower outer quadrant (post lumpectomy).tumor size : grey white ill defined lesion measures 0.9x0.6x0.2 cm in lower outer quadrant.margins of tumor : ill defined deep margin : 1.5 cmadjacent breast : 1.5x1 cmaxillary tail : 4x3x2 cm,section shows infiltrating neoplasm arranged in sheets. the cells are round to oval vesicular nuclei prominent nucleoli abundant eosinophilic cytoplasm. mitotic figures are seen 5 6 10 hpf. mild pleomorphism noted.,left breast left modified radical mastectomy(post lumpectomy). :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). tumor is located in the lower outer quadrant. tumor measures 0.9 cm in greatest dimension. lymphovascular invasion is not identified. perineural invasion is not identified. ductal carcinoma in situ of solid and cribriform pattern with intermediate nuclear grade is seen. posterior resection margin is free of tumor. nipple and aerola is unremarkable.lymph nodes :two out of sixteen lymph nodes show metastatic tumor deposit with extranodal extension(2 16). size of the larger tumor deposit measures 0.5 cm in greatest dimension.
MR1809180,right breast lump possibility of carcinoma breast.,right breast lump biopsy.,received 3 grey white linear cores measures 2 cm. each. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in cords and tubules. the cells have pleomorphic round hyperchromatic nucleus prominent nucleoli and moderate cytoplasm. mitotic is discerned.,right breast lump biopsy :invasive ductal carcinoma grade ii.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1809207,right breast lump carcinoma breast.,right breast lump biopsy.,received four grey white linear core each measures 1.5cm entire tissue processed.,section shows tumor cells in nests cords and sheets. individual cells have hyperchromatic nuclei and moderate cytoplasm.,right breast lump core biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1809208,left breast lump birads ivb,biopsy from left breast,received 4 grey white linear cores measures 1.5 2cm. entire tissue processed,section from breast parenchyma shows linear cores of fibrocollagenous tissue harboring neoplasm which is arranged in diffusely scattered sheets clusters and glandular patterntumor cells are large round to oval with abundant eosinophilic cytoplasm mild pleomorphic hyperchromatic nucleus. adjacent stroma showing desmoplastic change and lymphoplasmacytic infiltrates.,biopsy from left breast:invasive carcinoma nstmodified bloom richardson score is 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1809213,left breast lump possibility of carcinoma breast.,left breast lump biopsy.,received 4 grey white linear cores each measures 1 to 2cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in sheets cords and tubules. the cells have pleomorphic round nucleus dispersed chromatin prominent nucleoli and moderate cytoplasm. mitosis is discerned. ductal carcinoma in situ ( cribriform solid pattern) is seen.,invasive ductal carcinoma grade iimodified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........focus of ductal carcinoma in situ cribriform and solid pattern seen..
MR1809240,right breast lump possibility of carcinoma breast.,right breast lump biopsy.,received four grey white linear cores each measures 2cm. entire tissue processed.,section shows multiple cores breast parenchyma harboring infiltration lesion arranged in sheets and nests cord and sheets. individual cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. cells exhibit moderate nuclear pleomorphism.mitosis 4 5 10hpf. stroma is desmoplastic.,right breast core biopsy : invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1809283,left breast lump carcinoma breast.,left breast lump biopsy.,received three grey brown to grey yellow linear cores measures 0.8 to 1.5cm. entire tissue processed.,section shows multiple cores breast parenchyma harboring infiltration lesion arranged in sheets and nests tubules individual cells are round to oval having hyperchromatic nuclei and moderate cytoplasm cells exhibit moderate nuclear pleomorphism. intervening stroma is desmoplastic. mitosis 6 8 10hpf.,left breast biopsy : invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1809291,left breast lump carcinoma breast.,left breast lump biopsy.,received four grey brown linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple cores of breast paranchyma harboring a invasive neoplasm arranged in sheets cords and few tubules. individual cells are round to oval moderately pleomorphic hyperchromatic nuclei and moderate cytoplasm. few bizarre cells noted. mitosis is 5 6 10hpf.,left breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1809301,right breast lump carcinoma breast.,right breast lump biopsy.,received four linear core measures 1.5cm entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in tubules and cords. the cells have round hyperchromatic nucleus and moderate cytoplasm. surrounding stroma shows focal areas of myxoid change mitosis is discerned.,right breast lump core biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1809306,left breast lump possibility of carcinoma breast.,biopsy from left breast lump :,received 3 grey white linear cores each measures 1.5 x 0.2 x 0.2cm. entire tissue processed.,section from the breast parenchyma shows inflammatory infiltrate composed of lymphocytes and histiocytes. no evidence of malignancy in the specimen sent.,biopsy from left breast lump : chronic lymphocytic infiltrate with foci of calcification. kindly correlate with imageology and suggest repeat biopsy if deemed necessary.
MR1809320,left breast lump carcinoma breast,left breast lump core biopsy.,received 3 grey white linear cores each measures 2cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1809325,left breast lump carcinoma left breast.,biopsy from left breast,received of 4 grey white to grey brown linear cores measures 1.5x0.3x0.2cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrating by neoplasm cells arranged in sheets . the cells have pleomorphic round to irregular hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm. bizarre nuclear forms are seen. ductal carcinoma in situ component is noted( comedo pattern).,biopsy from left breast:invasive ductal carcinoma grade iimodified bloom richardson score is 3+2+2 7 9.ductal carcinoma in situ with comedonecrosis.
MR1809334,right breast lump possibility of carcinoma breast.,right breast lump biopsy.,received multiple grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section shows cores of tissue harboring a cellular lesion composed of fascicles and bundles of spindle cells with moderate pleomorphic hyperchromatic nuclei and few occasional mitotic figures .stroma is myxoid and hyalinged .,right breast lump biopsy :spindle cell lesion. suggest clinical correlation escision for further confirmation.
MR1809337,right breast lump o possibility of carcinoma breast.,right breast lump biopsy.,received 3 grey white linear cores each measures 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in sheets and cords. the lesion cells have round to irregular nucleus coarse chromatin prominent nucleoli and moderate cytoplasm. surrounding stroma shows desmoplasia. mitosis is discerned. ductal carcinoma in situ with comedonecrosis seen.,right breast lump biopsy:invasive ductal carcinoma grade 3modified bloom richardson score is 3+3+2 8 9.ductal carcinoma in situ with comedonecrosis.
MR1809359,right breast lump possibility of carcinoma breast,biopsy from right breast lump.,received 3 grey white linear cores each measures 1 1.2cm. entire tissue processed.,section shows fragmented tiny linear cores of fibrofatty tissue infiltrated by neoplastic cells in cords and sheets and abortive glandular pattern. the lesional cells have pleomorphic round to oval hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm. areas of necrosis is noted.,biopsy from right breast lump scanty tissue.suggestive of invasive carcinoma nuclear grade iinote:tissue is scanty suggest repeat biopsy to do immunohistochemistry.
MR1809363,left breast lump carcinoma breast.,left breast lump biopsy.,received four grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section shows fibrocollagenous tissue with focal areas of necrosis. no atypical cells seen.,left breast core biopsy :shows fibrocollagenous tissue with focal areas of necrosis. suggest repeat biopsy or excision of the lump for further conformation.
MR1809396,right breast lump.,right breast lump biopsy.,received 4 grey white linear cores each measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by a lesion arranged in sheets and nests with areas of pools of mucin. the cells have round to angulated hyperchromatic nucleus and moderate cytoplasm. few cells show signet ring like morphology. mitosis is discerned.,right breast lump biopsy :invasive carcinoma with mucinous features nuclear grade i.modified bloom richardson score is 4 9tubule formation : 2nuclear pleomorphism : 1mitotic figures : 1 4 9 .........
MR1809447,known case of carcinoma left breast post chemo residual lesion.,biopsy from left breast.,received 4 grey white linear core measures 0.5 to 1cm. entire tissue processed.,section studied shows tiny linear cores of tissue harboring residual carcinoma arranged in nests and vague glandular pattern. the lesional cells have moderate eosinophilic cytoplasm and round hyperchromatic nuclei. stroma shows desmoplasia.,left breast mass (post chemo) :shows small foci of residual ductal carcinoma in known and treated case.
MR1809466,left breast lesion,biopsy from left breast,received 4 linear cores measures 0.6 0.4cm. entire tissue processed.,section shows multiple cores of breast parenchyma with dilated ducts with stratified lining of round to oval cells having hyperchromatic nuclei and moderate amount of cytoplasm . these ducts are lined by myoepithelial cells abluminally. few ducts showing comedonecrosis. stroma shows lymphocytic infiltrate.,biopsy from left breast:extensive ductal carcinoma in situ ( cribriform and comedo type)intermediate nuclear grade no invasive component seen.
MR1809482,right breast lesion carcinoma breast.,biopsy from right breast lesion.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,linear cores of breast parenchyma harboring a neoplasm arranged as cords and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is elastotic.,biopsy from right breast. :invasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1809483,carcinoma right breast post nact.,right modified radical mastectomy post nact.,received in : formalin.laterality : right mrm.total dimensions : medial to lateral 21cm superficial to deep 5.5cm superior to inferior 20cmskin ellipse :15x8.5cmnipple : normal scar surgical measures : 3cm.tumor grey white : single.tumour size : 4.5x4.3x3cm ovarly skin is nodular grossly skin is free of tumor.location of tumor : upper and lower inner quardent.margins of tumor : illdefined. deep margin : 0.9cm.muscle : 4x2.5cm.adjacent breast : fibrofatty tissue. axillary tail : 7x5x3cm.size of largest node : 1.4x1x0.5cm infiltration.,sections show breast parenchyma with a tumor displaying cells arranged in sheets and clusters. the cells have moderate amount of eosinophilic to clear cytoplasm pleomorphic vesicular nuclei with prominent nucleoli mitotic activity discerned. stroma is desmoplastic with lymphomononuclear infiltrate. areas of hemorrhage and necrosis noted. extensive areas of ductal carcinoma in situ seen (comedo and solid type). lymphovascular invasion noted.,right modified radical mastectomy post nact:histological type:invasive carcinoma of ductal origin nst.grade:3tumor measures maximum dimension 4.5cminvasive component measures 4.5cmmodified br score is 9 9tubule formation: 3nuclear pleomorphism: 3mitotic figures: 3ductal carcinoma in situ present with comedonecrosis.lymphovascular invasion present.perineural invasion absent.posterior resection margin is free of tumor.nipple and areola is free of tumor.lymph nodes: 20 lymph nodes metastasis: 0(0 20).summary:invasive ductal carcinoma right breast.tumor grade: 3.lymphnode status: 0 20
MR1809543,left breast mass carcinoma breast.,biopsy from left breast lump.,received 5 grey linear cores measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in glands nests and trabecula. individual tumor cells are round to cuboidal with moderate eosinophilic cytoplasm pleomorphic hyperchromatic nuclei mitotic figures are 4 6 10hpf .stroma is desmoplastic.,biopsy from left breast mass. :invasive ductal carcinoma (nst) grade ii. modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 3mitotic figures : 1 6 9
MR1809547,right breast lump carcinoma breast.,right breast lump biopsy.,received 8 grey white linear cores measures 0.8 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an invasive neoplasm arranged in glandular pattern trabecular and nests. individual tumor cells are round to cuboidal mildly pleomorphic hyperchromatic nucleus and moderate cytoplasm stroma is desmoplastic.,biopsy from right breast lump. :invasive ductal carcinoma grade ii.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1809592,left breast lump possibility of carcinoma breast,biopsy from left breast lump.,received 4 grey white linear cores measures 1cm each. entire tissue processed.,section shows linear cores of breast parenchyma infiltrating by neoplastic cells arranged in sheets and tubules.the cells have round to angulated hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm. surrounding stroma shows desmoplasia.,biopsy from left breast lump:invasive carcinoma nst nuclear grade ii
MR1809593,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received 3 grey white linear cores measures 0.5 1 entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in tubules and cords. the cells lesion cells have round hyperchromatic nucleus and moderate cytoplasm. surrounding stroma is desmoplastic.,biopsy from left breast lump:invasive ductal carcinoma grade ii.modified bloom richardson score is 2+2+2 6 9.
MR1809604,right illiac region subcutaneous plane lesion deposit.,biopsy from illiac region subcutaneous plane.,received multiple grey white linear cores measures 1 to 1.5cm . entire tissue processed.,section shows multiple linear cores harboring a neoplasm arranged in sheets and nests. the cells are round to oval hyperchromatic nuclei scant to moderate amount of cytoplasm. few atypical mitotic figures identified. adjacent stroma shows lymphocytic infiltrate.,biopsy from illiac region subcutaneous plane. :metastatic deposits in a known case of carcinoma breast.
MR1809631,right breast lump possibility of carcinoma breast.,right breast lump core biopsy.,received 5 grey white to grey brown linear cores 0.5 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring infiltrating lesion arranged in cords nests and tubules. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. intervening stroma shows desmoplasia. mitosis 4 5 10 hpf.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1809632,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received 6 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged as cluster cells have hyperchromatic nuclear and moderate cytoplasm. the intervening stroma is elastatic.,biopsy from right breast lump. :invasive carcinoma grade iimodified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1809676,carcinoma right breast.,a) right breast right wide local excision.b) underlying pectoralis.c) right axillary dissection.d) level iii nodes.,a) received lumpectomy specimen measures 9x7.5x6cm. cut surface show grey white tumor measures 2x1.5x1cm.distance from the margins:superior margin 4.5cm.inferior margin 4cm.medial margin 2.5cm.lateral margin 2cm.deep margin 1cm.b) received fibrofatty tissue measures 2x1.5x0.6cm. entire tissue processed.c) received fibrofatty tissue measures 6.5x4.5x3cm. largest lymph node measures 2x1.2x0.8cm. cut surface is grey white.d) received fibrofatty tissue measures 2.5x0.2x0.5cm.,sections show breast parenchyma harboring an infiltrative lesion with cells arranged in sheets nests and clusters. the cells have scant to moderate clear cytoplasm pleomorphic round to oval nuclei with prominent nucleoli. atypical mitosis discerned (3 4 10hpf). surrounding stroma is desmoplastic with focal areas showing mucin pools.,a) right breast right wide local excision:invasive ductal carcinoma grade ii.modified bloom richardson score is 3+2+1 6 9.tumor measures 2cm in greatest dimension.lymphovascular invasion seen.all margins (superior inferior medial lateral deep) free of tumor.b) underlying pectoralis:free of tumor.c) right axillary dissection:one out of fifteen lymph nodes shows metastatic tumor deposit measures 1.2cm in greatest dimension.extranodal extension seen. (1 15)d) level iii nodes:ten nodes no deposits of tumor. (0 10)pathological grade : ypt1n1.
MR1809678,right breast lump possibility of carcinoma breast,biopsy from right breast lump.,received 3 grey white linear cores measures 1 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrating by neoplastic cells arranged in tubules and sheets with areas of necrosis. the cells have round hyperchromatic nucleus and moderate cytoplasm. atypical mitotic figures are noted. foreign body giant cells seen.,biopsy from right breast lump:invasive carcinoma nst grade iii. metastatic carcinomamodified bloom richardson score is 3+2+3 8 9.
MR1809679,right breast lump possibility of carcinoma breast,biopsy from right breast lump.,received 4 grey white linear cores each measures 1.5cm. in length. entire tissue processed.,section shows linear cores of breast parenchyma infiltrating by neoplastic cells arranged in sheets cords and tubules with areas of necrosis and hyalinization. the cells have pleomorphic round hyperchromatic nucleus and moderate cytoplasm. mitosis is discerned.,biopsy from right breast lump:invasive ductal carcinoma grade iii.modified bloom richardson score is 3+2+3 8 9.areas of necrosis noted.
MR1809684,left breast lump carcinoma breast,biopsy from left breast.,received 4 grey white linear cores measures 0.8 1cm. entire tissue processed.,section shows linear cores of breast parenchyma with extensive areas of hyalinisation with few benign ductal clusters and occasional focus shows hyperplastic stroma with compressed ducts. no atypia is seen.,biopsy from left breast:suggestive of fibroepithelial lesion.no evidence of malignancy.suggest repeat if clinically correlated.
MR1809712,right breast lump carcinoma breast.,biopsy from right breast.,received multiple grey white linear cores measures 0.8 to 1.5cm. entire tissue processed.,sections show linear cores of fibrous tissue with few foci showing ductal carcinoma in situ (comedo type). some fragments display desmoplastic stroma.,biopsy from right breast:foci of ductal carcinoma in situ seen high grade with comedo necrosis.no evidence of invasive component.suggest repeat biopsy from more representative areas for confirmation of invasion and hormone status evaluation.
MR1809713,right breast mass,biopsy from right breast mass.,received 5 grey white linear cores measures 1.2 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrating by neoplastic cells arranged in sheets and cords . the cells have round to pleomorphic hyperchromatic nucleus and moderate cytoplasm. mitosis is discerned.,biopsy from right breast mass:invasive carcinoma with lobular features grade ii.modified bloom richardson score is 2+2+2 6 9.
MR1809720,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 6 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma showing extensive areas of ductal carcinoma in situ with focus of invasion. the lesional cells have round hyperchromatic nucleus and moderate cytoplasm. mucin pools are noted focally.,left breast lump biopsy :extensive ductal carcinoma in situ ( solid and mucinous) with focus of invasion . nuclear grade 2
MR1809724,left breast lump possibility of carcinoma breast,biopsy from left breast lump.,received 4 grey white linear cores measures 1cm in length. entire tissue processed.,section shows linear cores of breast parenchyma harboring an invasive neoplasm arranged in cords and tubules. the lesional cells have round hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm. mitosis is discerned. marked desmoplasia noted.,biopsy from left breast lump:invasive ductal carcinoma grade 2.modified bloom richardson score is 2+2+2 6 9.
MR1809744,left breast lump possibility of carcinoma breast,biopsy from left breast lump.,received 4 grey white linear cores measures 1 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrating by neoplastic cells arranged in cords and tubules. the lesional cells have round to angulated hyperchromatic nucleoli and moderate cytoplasm. mitosis is discerned. surrounding stroma shows desmoplasia.,biopsy from left breast lump:invasive ductal carcinoma grade i.modified bloom richardson score is 2+2+1 5 9.
MR1809757,right breast mas,biopsy from right breast mass.,received 4 grey white linear cores measures 1.5cm each. entire tissue processed.,section shows linear cores of breast parenchyma with ductal carcinoma in situ component ( solid pattern) with focus of invasion. the cells have round hyperchromatic nucleus and moderate cytoplasm. marked desmoplasia seen,biopsy from right breast mass:extensive ductal carcinoma in situ with focus of invasion.suggest repeat biopsy for ihc.
MR1809763,known case of carcinoma breast.,biopsy from left supraclavicular node,received 3 grey white linear cores measures 1.5cm entire tissue processed.,section shows linear cores of fibrocollagenous tissue infiltrated by tumor cells arranged in tubules and cords with areas of necrosis. the lesional cells have round pleomorphic hyperchromatic nucleus and moderate cytoplasm. surrounding stroma shows desmoplasia.,biopsy from left supraclavicular nodefeatures are suggestive of metastatic adenocarcinoma.
MR1809794,carcinoma left breast,sternum lytic lesion biopsy.,received single bony linear cores measures 1.5cmin length. entire tissue processed.,section shows fibrocollagenous stroma with a bony trabeculae showing infiltrative neoplasm arranged in sheets nests and cribriform pattern. the cells are round to oval hyperchromatic nuclei prominent nucleoli and moderate to abundant cytoplasm. areas of necrosis and atypical mitotic figures are noted.,sternum lytic lesion biopsy:suggestive of metastatic carcinoma in a known case of carcinoma left breast.
MR1809810,carcinoma left breast.,a) breast conservative surgery wide excision.b) axillary lymph node.,a) received lumpectomy specimen measures 6x3x3cm. skin measures 6x1cm. cut surface no tumor identified grey white granular areas seen measuring 1.5x0.5x0.5cm near inferior margin.b) received multiple fibrofatty tissue measures 7x5.4cm.largest lymph node measures 2x1.5x1cm. cut surface shows fat infiltration.,a) tumor bed:the section show fibrotic areas collagenous tissue focal lymphoplasmacytic infiltration and atropic ducts. there is no evidence of residual viable tumor . all resected margins are free from the tumor.b) 13 nodes. no metastatic depsoits of tumor present.,a) breast conservative surgery wide excision:no residual viable tumor.fibrotic and lymphoplasmacytic infiltrate seen.all resected margins are free from the tumor.b) axillary lymph node:13 nodes. no metastatic depsoits of tumor present. 0 13
MR1809834,right breast lump possibility of carcinoma breast.,biopsy from right breast lump,received 4 grey white linear cores measures 1 cm in length. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in tubules. the cells have round to angulated hyperchromatic nucleus and moderate cytoplasm.mitosis is discerned. stroma show desmoplasia.,biopsy from right breast lump:invasive ductal carcinoma grade ii.modified bloom richardson score is 2+2+2 6 9.
MR1809873,left breast lump carcinoma breast.,biopsy from left breast breast.,received grey white linear cores 1cm. entire tissue processed.,section show linear tissue cores harboring an infiltrative neoplasm arranged in cords nests and trabeculae. the individual tumor cells show increased n c ratio pleomorphic hyperchromatic nuclei with conspicuous nucleoli and moderate to abundant amount of pale eosinophilic cytoplasm. numerous atypical mitotic figures are noted. the intervening stroma shows presence of dense fibrocollagenous connective tissue. infiltrated by few lymphocytes. focal areas of necrosis noted.,biopsy from left breast breast:invasive carcinoma breast nos grade ii.modified bloom richardson score is 7 9 ( 3+2+2)
MR1809883,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 4 grey white to grey brown linear cores measures 1 1.2cm. entire tissue processed.,linear cores of breast parenchyma harboring a neoplasm arranged as tubules and cords. the neoplastic cells are cuboidal have hyperchromatic nuclei and moderate cytoplasm.. the intervening stroma is elastotic.,biopsy from left breast lump:invasive carcinoma nstmodified bloom richardson score is 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1809907,right breast lump carcinoma breast,biopsy from right breast lump.,received 4 grey white linear cores measures 1cm. entire tissue processed.,section show linear tissue cores harboring an infiltrating neoplasm arranged in irregular glandular architecture and cords of neoplastic cells exhibiting. increased n c ratio pleomorphic hyperchromatic nuclei occasional conspicuous nucleoli and scanty cytoplasm. the intervening stroma shows presence of dense fibrocollagenous connective tissue and focal adipose tissue.,biopsy from right breast lump:invasive carcinoma nos grade ii.modified bloom richardson score is 6 9(2+2+2).
MR1809918,right breast lesion carcinoma breast.,right breast core biopsy.,received 4 grey white linear cores measures 0.8 1cm. entire tissue processed.,section shows from the breast parenchyma sows a lesion arranged in sheets and nests. the cells are round to oval with hyperchromatic nuclei and moderate eosinophilic cytoplasm. atypical mitotic figures are noted. ductal carcinoma in situ component seen. adjacent stroma shows lymphocytic infiltrate.,right breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). ductal carcinoma in situ seen solid cribriform pattern with intermediate nuclear grade.
MR1809958,left breast lump carcinoma breast,left breast lump biopsy,received 3 grey white to grey brown linear cores measures0.5 0.8cm. entire tissue processed.,section from the breast parenchyma shows a lesion arranged in cords and occasional nests. the cells have round to oval hyperchromatic nuclei and scant to moderate amount of cytoplasm. adjacent stroma show lymphocytic infiltrates. mitotic figures are seen.,left breast lump biopsy:shows atypical cells in cords and occasional nests highly suspicious of malignancy.note: marked crushing artifacts are identified which limits the microscopic evaluation.suggest repeat biopsy or excision of the lump for further confirmation.
MR1809981,lump right breast.,right breast lump core biopsy.,received 4 grey white linear cores measures 0.5 1cm. entire tissue processed.,section shows multiple cores of breast parenchyma with infiltrating neoplasm arranged in sheets and nests. the cells are round to oval hyperchromatic nuclei. scant to moderate cytoplasm. atypical mitotic figures seen. adjacent stroma shows lymphocytic infiltrate.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1809985,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 1.5 2cm. entire tissue processed.,section show linear cores of fibrocollagenous tissue harboring scant volume of neoplasm arranged in ductal nested pattern. neoplastic cells are round to oval with clear to eosinophilic cytoplasm and mild pleomorphic hyperchromatic nuclei abundant . stroma shows desmoplastic change and inflammatory infiltrate.,biopsy from left breast lump:scant volume of atypical cells suggestive of invasive carcinoma.note: tumor volume may not be adequate for ihc .
MR1810072,carcinoma breast,biopsy from right breast,received 4 linear cores measures 0.8 1cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in nests and islands. the individual lesion cells are consisting of round to oval moderately hyperchromatic nuclei with inconspicuous nucleoli and abundant eosinophilic to clear cytoplasm. mitotic activity discerned. intervening stroma showing desmoplastic change and lymphoplasmacytic infiltrate.,biopsy from right breast:invasive carcinoma.(nuclear grade2)
MR1810089,carcinoma right breast,biopsy from right breast.,received 6 linear cores measures 0.8 1cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in tubules and sheets. the individual lesion cell are consisting of round to oval markedly pleomorphic nuclei with inconspicuous nucleoli and abundant eosinophilic cytoplasm. mitotic activity is discerned. the intervening stroma showing inflammatory infiltrate consisting of lymphocytes and histiocytes.,biopsy from right breast.invasive ductal cell carcinomamodified bloom richardson score is 6 9(1+3+2)
MR1810108,right breast lump recurrent,biopsy from right breast biopsy.,received 4 linear cores measures 0.6 0.7cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets and nests the cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. stroma is desmoplastic mitosis 6 7 10 hpf. focal necrosis seen,biopsy from right breast biopsy:invasive carcinoma grade ii.modified bloom richardson score is 7 9(3+2+2).
MR1810174,left breast lump possibility of carcinoma breast,biopsy from left breast lump.,received 4 linear cores measures 0.4 0.6cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in cords sheets cells exhibit moderate cytoplasm. hyperchromatic nuclei. mitosis 2 3 10 hpf.,biopsy from left breast lesion:invasive carcinoma grade iimodified bloom richardson score is 6 9(3+2+1).
MR1810176,carcinoma breast,biopsy from left breast lesion,received 4 linear cores measures 0.8 0.9cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets cords nests and tubules. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit nuclear pleomorphism. stroma is desmoplastic mitosis 3 4 10 hpf.,biopsy from left breast lesion:invasive ductal carcinoma grade iimodified bloom richardson score is 6 9(3+2+1).
MR1810177,left breast lump carcinoma breast,biopsy from left breast lump,received 5 linear cores measures 0.8 1cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in cords nests . the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit nuclear pleomorphism. mitosis 2 3 10 hpf.,biopsy from left breast lesion:invasive ductal carcinoma grade iimodified bloom richardson score is 6 9 (3+2+1).
MR1810194,carcinoma breast.,endometrial tissue features suggestive of proliferative phase endometrium.,received multiple grey brown soft tissue bits altogether measures 3.5x2x0.5cm. entire tissue processed.,sections show fragments of endometrium composed of short trabecular to elongated glands lined by columnar epithelium with nuclear stratification. stroma shows plump spindle to oval cells. areas of edema and hemorrhage noted. occasional lymphoid aggregate is noted.,endometrial tissue biopsy :features are suggestive of proliferative endometrium.no evidence of malignancy is seen.
MR1810252,carcinoma right breast,a) right breast wide excisionb) revised superior marginc) axillary lymph node dissection,a) received wide local excision specimen measures 9x6x4.5cmskin ellipse measure 4.5cmcut surface of the tumor measures 1x0.5x0.5cmdistance from marginssuperior margin : 1.0cminferior margin :3.6cmmedial margin : 4.5cmlateral margin : 1.6cmdeep margin : 2.3cmb) received fibrofatty tissue measures 2.2x0.5x0.5cmc) received fibrofatty tissue measures 6.5x5.5x4cmlargest lymph node measures 1.6x1x0.5cmcut surface shows grey white deposit measures 0.5x0.5x0.4cm.,a) section studied show breast parenchyma harboring an infiltrating lesion arranged in sheets and focal tubules. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleli. mitotic figures are discerned. stroma is demsoplastic with moderately dense lymphomononuclear infiltrate.,a) right breast wide excision:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation :3nuclear pleomorphism : 2mitotic figures : 2tumor measures 1cm in greatest dimension.invasive component measures 0.8cm in greatest dimension.ductal carcinoma measures 0.2cm solid pattern.lymphovascular invasion and perineural invasion are not seen.all margins of resection ( superior inferior medial lateral and deep) are free of tumor.b) revised superior margin:free of tumorc) axillary lymph node dissection:one of the four isolated lymph nodes sow metastatic tumor deposit 1 4 perinodal spread is not seenpathological grade : pt1n1.
MR1810261,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received 3 linear cores grey white measures 1.8 0.3cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in tubules nests. the cells are ovoid having moderate amount of pale eosinophilic cytoplasm and hyperchromatic nucleus. mitotic figures are discerned. stroma shows desmoplasia with areas of hemorrhage and lymphomononuclear cell infiltrate.,biopsy from left breast lump:invasive carcinoma nst grade 2modified bloom richardson score is 6 9(2+2+2).
MR1810301,left breast lump carcinoma breast,biopsy from left breast lump,received 5 grey white linear tissue bits measures 2 0.8cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in nests and cords. the cells are ovoid having moderate amount of cytoplasm and hyperchromatic nucleus with prominent nucleoli in few. mitotic figures are discerned. intervening stroma shows dense lymphomononuclear cell infiltrate. areas of hemorrhage noted.,biopsy from left breast lump:invasive carcinoma nst grade 2modified bloom richardson score is 7 9(3+2+2).
MR1810321,left breast lump carcinoma breast.,biopsy from left breast,received 5 grey white linear cores measures 2 2.5cm. entire tissue processed.,linear cores of breast parenchyma harboring a neoplasm arranged as islands and clusters. the neoplastic cells are cuboidal have hyperchromatic nuclei and moderate cytoplasm. foci of comedo and solid noted ductal carcinoma in situ seen.,biopsy from left breast:invasive carcinoma nst. grade 2modified bloom richardson score is 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1810338,right breast lump carcinoma breast.,biopsy from right breast lump.,received 5 grey white linear cores measures 1 1.2cm. entire tissue processed.,section section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in sheets and tubules. the individual lesion cells are consisting of round to oval hyperchromatic nuclei with inconspicuous nucleoli and abundant eosinophilic cytoplasm mitotic activity is discerned. adjacent stroma showing lymphoplasmacytic infiltrate and desmoplastic changes.,biopsy from right breast lump:invasive ductal carcinoma grade 2.modified bloom richardson score is 2+2+3 7 9.
MR1810372,possibility of carcinoma right breast.,biopsy from right breast,received 4 linear cores measures1 1.2cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets and nests. the cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. mitosis 3 4 10hp,biopsy from right breast:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9(3+2+1).areas of mucin seen.
MR1810374,left breast lump carcinoma breast.,biopsy from left breast,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,sections shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in cords and nests. the individual lesion cells are consisting of round to oval markedly pleomorphic eccentrically placed hyperchromatic nuclei with inconspicuous nucleoli and abundant amount of eosinophilic cytoplasm. mitotic activity is discerned. stroma showing desmoplasia and and lymphoplasmacytic infiltrate.,biopsy from left breast:invasive carcinoma ( nuclear grade 2)
MR1810404,right breast lump to rule out carcinoma breast,biopsy from right breast lump,received 7 grey white linear cores measures 0.6 1.5cm. entire tissue processed.,section studied from linear core of breast parenchyma show ducts of varying size which are lined by inner oval cell having hyperchromatic nuclei and intact outer myoepithelial layer. ductal epithelial also show focal areas of stratification apical snouting columnar cell change as well as apocrine change. few focus show focal ductal hyperplasia stroma is edematous mildly cellular with myxoid change and thin walled dilated and congested blood vessels.,biopsy from right breast lump:proliferative breast disease. fibroadenoma. phyllodes
MR1810433,left breast lump carcinoma breast,left breast lump core biopsy.,received 5 grey white linear cores measures 1 1.5cm. entire tissue processed,section shows linear cores of breast parenchyma infiltrating by neoplastic ells arranged in cords and tubules. the neoplastic cells have round hyperchromatic nucleus and moderate cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1810463,left breast lump birads iv lesion.,left breast core biopsy.,received multiple grey white linear cores measures 1 1.5cm. entire tissue processed.,sections hows cores breast tissue infiltrated by ductal carcinoma in situ of solid cribriform and comedo pattern. no definite evidence of invasion is seen.,left breast core biopsy:shows ductal carcinoma in situ of solid cribriform and comedo pattern with intermediate nuclear grade.no definite evidence of invasion is seen.
MR1810478,left breast lump possibility of carcinoma breast.,left breast lump core biopsy.,received four grey white linear cores measures 1.5 2cm. entire tissue processed.,section shows multiple linear cores with infiltrating neoplasm arranged in sheets nests and occasional tubules. cells foaming lesion are round to oval with hyperchromatic nuclei and abundant eosinophilic cytoplasm. adjacent stroma shows lymphoplasmacytic infiltrates. mitotic figures noted.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1810484,carcinoma right breast.,a)right breast conservative surgery.b)right axillary lymph node.,a) right breast conservative surgery.received breast conservative surgery specimen measures 9x7.5x3.5cm.skin ellipse measures 7.5cm. an area of puckering noted measures 1x1cm. cut surface shows grey white lesion measures 2.5x2x1.5cm.lesion found close to skin. located at the following distance from margins.superior margin 2cm.interior margin 1.8cm.medial margin 1.5cm.lateral margin 2cm.deep margin 1.8cm.b) axillary lymph node.received two fibrofatty tissue measures 5x5x2.2cm.,a)right breast conservative surgery:the tumor is composed of pleomorphic cells with hyperchromatic nucleus with scanty cytoplasm. the cells are present in clumps groups and sheets.the tumor is present in skin epidermis is free from the tumor.tubular formation is less than 10 3anaplasia 2mitotic figures are 8 10 hpf 2modified bloom richardson score 7 9. nuclear grade ll. ductal carcinoma in situ not identified.lymphovascular invasion not identified.perineural invasion not identified.resected margins are superior margin free of tumor.inferior margin free of tumor.radial margin free of tumor.lateral margin free of tumor.deep margin free of tumor.b) axillary lymph node:7 nodes : no deposits of tumor.(0 7),a) right breast conservative surgery:invasive ductal carcinoma maximum dimension of tumor is 2.5x2x1.5cm.nuclear grade llthe tumor is present below the skin epidermis is free from the tumor.ductal carcinoma in situ not identified.lymphovasicular invasion not identified.perineural invasion not identified.all resected margins are free of tumor.b) axillary lymph node:7 nodes. no deposits of tumor.(0 7)pathological grade pt2n0.
MR1810502,right breast lump carcinoma breast,right breast lump core biopsy.,received five grey white linear cores measures 1 1.5cm. entire tissue processed,section from the breast parenchyma shows infiltrating neoplasm arranged in sheets and nests. the cells are round to oval vesicular nuclei prominent nucleoli and abundant eosinophilic cytoplasm. adjacent lymphoplasmacytic infiltrate. atypical mitotic figures.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1810525,left breast lump carcinoma breast.,left breast core biopsy.,received five grey white linear cores measures 1.5 2cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma showing infiltrating neoplasm arranged in sheets and nests. cells are round to oval hyperchromatic nuclei moderate nuclear pleomorphism seen. adjacent stroma shows lymphoplasmacytic infiltrates. areas of necrosis seen . mitotic figure noted.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1810530,right breast lump carcinoma breast.,biopsy from right breast lump,received 4 grey white linear cores measures 1.5 2cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets and nests. the lesional cells are round to oval having hyperchromatic nuclei. scant cytoplasm. cells exhibit moderate nuclear pleomorphism. stroma shows desmoplasia mitosis 10 12 10 hpf.,biopsy from right breast lump:invasive carcinoma grade iiimodified bloom richardson 8 9 (3+2+3).
MR1810539,carcinoma right buccal mucosa,biopsy from right buccal mucosa.,received 1 grey white soft tissue measures 0.9x0.5x0.1cm. entire tissue processed.,section shows fragments of breast mucosa exhibiting mild acanthosis. subjacent stroma show band of lymphocytic inflammatory cell infiltrate with associated crush artifacts.,biopsy from right buccal mucosa:no evidence of malignancy in submitted tissue bits.
MR1810546,left breast lump carcinoma breast.,left breast lump biopsy,received 6 grey white linear cores measures 1.5 2cm. entire tissue processed.,section shows multiple fragments of breast parenchyma shows infiltrative neoplasm arranged in nests and occasional tubules. cells forming the lesion are round to oval with vesicular nuclei prominent nucleoli and moderate amount of cytoplasm. mitotic figures seen. lymphoplasmacytic infiltrate seen.,left breast lump biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1810554,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 7 grey white linear cores measures 1.5 2cm. entire tissue processed.,section shows breast parenchyma harboring infiltrating lesion arranged in sheets and nests. the cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. intervening stroma shows lymphoplasmacytic infiltrate. cells exhibit marked nuclear pleomorphism. mitosis 6 8 10 hpf.,biopsy from left breast lump:invasive carcinomasuggestive of invasive ductal carcinoma grade 3.modified bloom richardson score 8 9(3+3+2)
MR1810560,right breast lump possibility of carcinoma breast,trucut biopsy right breast lump,received 5 grey white linear cores measures 1.5 2cm. entire tissue processed,section shows multiple cores of breast parenchyma harboring lesion arranged in sheets nests and cords. the lesional cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. stroma shows sclerosis . focus of mucin seen. ductal carcinoma in situ seen. mitosis 4 5 10 hpf.,right breast lump biopsyinvasive ductal carcinoma grade 2modified bloom richardson score is 6 9 (3+2+1).
MR1810584,carcinoma left breast.,cone excision of the ductal system left breast.,received fibrofatty tissue measures 6x6x2.5cm. cut surface shows dilated duct with granular grey white lesion in lumen measures 2x1.5x1cm. distance of lesion from respective margins :superior margin : 0.5 cm.inferior margin : 0.6 cm.medial margin : 0.2 cm.lateral margin : 2.3 cm.deep margin : 1 cm.,section studied show breast parenchyma with dilated ducts of varying site few of which are lined by cellular branching papillae. the cells lining the papillae show epithelial cells with focal stratification. the cells are ovoid to low columnar having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. occasional mitotic figures are seen. no frank invasion is noted. adjacent breast parenchyma shows areas of hyalinisation and adenosis.,cone excision of the ductal system left breast. intraductal papilloma. no invasive carcinoma. lesion measures 2cm in greatest dimension. superior and medial margins show intraductal papilloma. inferior and lateral margins are free of tumor.
MR1810598,left breast lump birads iv.,biopsy from left breast lump.,received 5 grey white linear cores measures 1.5 2cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets and nests. the cells are round to oval having hyperchromatic nuclei moderate eosinophilic cytoplasm. cells exhibit moderate nuclear pleomorphism. stroma shows desmoplasia. mitosis 5 6 10 hpf.,biopsy from left breast lump:invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9(3+2+2).
MR1810601,right breast mass.,biopsy from right breast mass.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in tubules nests cribriform pattern. the cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. the cells exhibit mild nuclear pleomorphism mucin seen. lymphocytic infiltrate seen in stroma.,right breast mass biopsy :invasive carcinoma with mucinous features grade i. modified bloom richardson score is 4 9tubule formation : 2nuclear pleomorphism : 1mitotic figures : 1 4 9 .........
MR1810647,left breast lump carcinoma breast,biopsy from left breast lump.,received 4 grey white linear cores measures 2 2.5cm. entire tissue processed.,section shows multiple linear cores from breast parenchyma harboring a neoplasm arranged in sheets nests acini. the cells are round to oval vesicular nuclei. adjacent lymphoplasmacytic infiltrate seen. mitosis 5 6 10 hpf . extensive areas of necrosis noted.,biopsy from left breast lump:invasive carcinoma nst grade 2modified bloom richardson score is 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1810723,left breast lesion carcinoma breast.,biopsy from left breast lesion.,received 4 grey white linear cores measures 1.5 2cm. entire tissue processed.,section from the breast parenchyma with infiltrating neoplasm arranged in sheets and nests. the cells are round to oval hyperchromatic nuclei scant to moderate clear cytoplasm. adjacent stroma shows lymphoplasmacytic infiltrates. mitosis 4 5 10hpf.,biopsy from left breast lesion:invasive ductal carcinoma grade 2. modified bloom richardson score is 6 (3+2+1).
MR1810753,ill defined suspicuous lesion in right breast,biopsy from right breast 7 8 0 clock position,received 3 grey white linear cores measures 2 2.5cm. entire tissue processed,sections shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in cords and sheets. the lesional cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. mitosis 3 4 10 hpf.,biopsy from right breast 7 8 0 clock position:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9 (3+2+1)
MR1810756,right breast lump.,biopsy from right breast lump,received 5 grey white linear cores measures 1.5 2cm. entire tissue processed,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets cores tubules. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. stroma shows desmoplasia. mitosis 4 5 10hpf.,biopsy from right breast lump:invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9( 3+2+1).ductal carcinoma in situ ( comedo type) noted with intermediate nuclear grade.
MR1810797,right breast lump.,a) specimen of right sentinel node biopsy. b) right breast wide excision (lumpectomy).,a) received 2 lymphnodes largest measures 1.6x1.5x0.4cm. smaller measures 0.8x1x0.3cm. b) received lumpectomy measures 5.5x4.5x1.5cm. skin measures 5.5x2cm. cut surface shows grey white tumor measures 1.5x1x0.8cm.distance from margins :superior margin : 1.2cm.inferior margin : 2 cm.medial margin : 1.8 cm.lateral margin : 2.5 cm.deep margin : 1.5 cm.skin ellipse 1.7cm.,sections studied shows breast parenchyma harboring an infiltrating lesion arranged in cords and vague nests. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. extensive ductal carcinoma is situ solid pattern is noted. stroma shows desmoplasia with moderately dense lymphomononuclear cell infiltrate.,a) right sentinel lymphnode biopsy. isolated two lymphnodes are free of tumor (0 2)b) lumpectomy :invasive ductal carcinoma grade 2modified br score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 ................. 7 9 ..................maximum dimension of the tumor is 1.5x1x0.8cm. ductal carcinoma in situ with solid pattern is noted. measuring 0.3cm. lymphovascular invasion and perineural invasion are not identified.all margins of resection (superior inferior medial lateral and deep) are free of tumor. pathological stage : pt1n0.
MR1810804,left breast lump carcinoma breast,biopsy from left breast lump,received 4 linear cores measures 2 2.5cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets nests and cords. the lesional cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. stroma shows desmoplasia with lymphocytic infiltrate. mitosis 8 9 10 hpf. ductal carcinoma (solid type )noted.,biopsy from left breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9(3+2+2).ductal carcinoma in situ solid type intermediate nuclear grade.
MR1810827,left breast carcinoma.,a)left wide local excisionb)left sentinel lymph node biopsyc)revised deep margind) revised lateral margine)revised superior marginf)left axillary dissection,a) received single skin cover fibrofatty tissue measures 8x7x4cm. skin ellipse measures 6x3cm. surface of skin unremarkable. distance from margins : superior margin : 0.5cm.inferior margin : 1.0 cm.medial margin : 1.5 cm.lateral margin : 0.3cm.cutsurface shows ill defined lesion measures 2x1.5x1.0cm. deep margin 0.4cm. b) sentinel nodes : received fibrofatty tissue measures 2x1.5x1cm. isolated 2 lymphnodes. largest lymph node measures 1x1x0.5cm. cutsurface fatty infiltration. c) received fibrofatty tissue measures 5x3x1.5cm. inked away from tumor. d) received fibrofatty tissue measures 7x3x1.5cm. inked away from tumor. e) received fibrofatty tissue measures 6x3x2cm. inked away from tumor. f) received fibrofatty tissue measures 5x5x4cm. largest lymphnode measures 2x1x1cm. cutsurface fatty infiltrate.,a) left breast conservative surgery wide local excision tumor is harboring pleomorphic cells with pleomorphic vesicular nucleus and eosinophilic cytoplasm. tumor maximum dimension measures 2x1.5cm. invasive component measures 1.5cm. ductal carcinoma in situ seen in solid and cribriform pattern. mbr score 6 9tubular formation : 2mitotic figures : 2nuclear pleomorphism : 2 ........... 6 9 ............lymphovascular invasion present. perineural invasion not identified. resected margins :a) superior and lateral margins are involved by tumor and shows invasive ductal carcinoma. deep margin shows ductal carcinoma in situ cribriform pattern. inferior and medial margins are free from tumor. b) sentinel lymphnodes. one node shows metastatic deposits of tumor out of 2 nodes (1 2)c) revised deep margins.free from tumor.d) revised lateral margin. free from tumor. e) revised superior margin : in focal few ducts show ductal carcinoma in situ cribriform pattern. however inked margin is free from the tumor. f) axillary lymph nodes. :2 nodes show metastatic deposits of tumor out of 15nodes (2 15)perinodal spread present.,a) left breast wide local excision :invasive ductal carcinoma with ductal carcinoma in situtumor maximum dimension measures 2x1.5cm. invasive component measures 1.5cm. nuclear grade ii.ductal carcinoma in situ (solid and cribriform pattern) measures 0.5cm. lymphovascular invasion present.perineural invasion absent. revised superior margin inked margin in free from the tumor. revised lateral margin free of tumor.revised deep margin free of tumor. lymphnodes :sentinel lymphnodes : 1 node shows metastatic deposits of tumor out of 2 nodes (1 2)axillary lymph nodes : 2 nodes show metastatic deposits of tumor out of 15nodes (2 15)total no. of nodes : 3 nodes positive out of 17 nodes (3 17)perinodal spread present.
MR1810852,carcinoma right breast.,a) wide local excision right breast. :b) right axillary level i and ii lymphnodes. :,a) received fibrofatty tissue measures 8x5x3.5cm.skin flap .measures 3x0.5cm . serial section shows circumscribed lesion measures 3.3x2.9x2.5cm. solid grey white firm. distance from margins:superior margin : 1.5cminferior margin : 2 cm.medial margin : 2 cm.lateral margin : 2.3cm.deep margin : 0.3 cm.b) received fibro fatty tissue measures 3x2x1cm. largest lymphnode measures 1.5x1x0.8cm.,a) section studied shows breast parenchyma harboring an infiltrating lesion arranged in sheets and nodules separated by fibrocollagenous tissue. the cells are ovoid having moderate amount of cytoplasm vesicular nucleus and prominent nucleoli.mitotic figures are discerned (6 7 10hpf). interspersed are numerous lymphomononuclear cell infiltrates. stroma mild desmoplasia with areas of hemorrhage. ductal carcinoma in situ is not present.,a) wide local excision right breast. :invasive carcinoma with medullary features grade 2.modified br score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 .......... 7 9 ...........tumor measures 3.3cm in greatest dimension.ductal carcinoma in situ not identified. lymphovascular invasion and perinodal invasion are not identified. all margins of resection (superior inferior medial lateral and deep) are free of tumor. b) right axillary level i and ii lymphnodes. :isolated twelve lymphnodes.all are free of tumor. (0 12)pathological grade : pt2n0.
MR1810881,known case of carcinoma cervix and carcinoma breast,left lung mass biopsy.,received multiple linear cores measures 1.5 2cm. entire tissue processed,section shows fibrocollagenous tissue infiltrated by neoplastic cells in sheets with intervening fibrous septa.the lesional cells are larger round to irregular with hyperchromatic nucleus inconspicuous nucleoli and moderate amount of amount of pale eosinophilic cytoplasm. adjacent stroma show lymphocytic infiltrate.,left lung mass biopsy:metastatic carcinoma from cervix.suggest ihc.
MR1810884,right breast lump to rule out carcinoma breast.,a)biopsy from right breastb) biopsy from left breast,a)received 4 grey white linear cores measures 0.8 2.0cm. entire tissue processed.b)received 4 grey white linear cores measures 0.8 2.0cm. entire tissue processed.,a)section shows cores of tissue harboring an invasive neoplasm in sheets and nests composed of cells with moderate eosinophilic cytoplasm round to oval hyperchromatic nuclei . stroma is desmoplastic. areas of necrosis seen.b) section shows cores of fibroadipose tissue harboring an invasive neoplasm in sheets and nests composed of cells with moderate eosinophilic cytoplasm round to oval hyperchromatic nuclei stroma is desmoplastic.,a)biopsy from right breast:invasive carcinoma nst grade 2 modified bloom richardson score is (3+2+1)6 9b) biopsy from left breast:invasive carcinoma nst grade 2 modified bloom richardson score is (3+2+1)6 9.
MR1810899,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measure 1.5 2cm. entire tissue processed.,section shows linear cores measures tissue predominantly composed of cells with moderate eosinophilic to clear cytoplasm hyperchromatic nuclei with moderate pleomorphism and increased mitosis. stroma is desmoplastic extensive peritumoral inflammatory infiltrate noted.,biopsy from left breast lump:invasive carcinoma nst grade iiimodified bloom richardson score is 3+2+3 8 9
MR1810901,left breast lump carcinoma breast.,biopsy from left breast lump,received4 grey white linear cores measures 1.2 1.5cm. entire tissue processed.,section studied shows linear cores of fibrous tissue harboring an infiltrating lesion arranged in nests and sheets. the cells are ovoid having moderate amount of cytoplasm pleomorphic hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with mild mild lymphomononuclear cell infiltrate.,biopsy from left breast lump:invasive carcinoma nst grade 2modified bloom richardson score is 7 9(3+2+2)
MR1810914,left breast lump carcinoma breast,biopsy from left breast lump.,received 4 grey white linear cores measures 1 1.5cm.entire tissue processed.,section shows cores breast parenchyma harboring an high grade ductal carcinoma in situ with occasional suspicious foci of invasion. stroma is dense and hyalinized. areas of comedonecrosis noted.,biopsy from left breast lump:highly suspicious for invasive carcinoma with predominant foci showing in situ component.see commentcomment:there are occasional foci which are suspicious of invasion with predominant in situ component.receptor status evaluation may be difficult in the present biopsy
MR1810919,right breast lump carcinoma breast.,right breast lump biopsy.,received three grey white linear cores measures 1.5 2 cm. entire tissue processed.,section from the breast parenchyma shows infiltrating neoplasm arranged in sheets and nests. the cells are round to oval hyperchromatic nuclei abundant eosinophilic cytoplasm. admixed lymphoplasmacytic infiltrates. mitotic figures 4 5 10 hpf.few cells are showing bizarre nuclei.,right breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+3+1).
MR1810922,lobulated lesion in left breast carcinoma breast.,left breast lesion biopsy.,received 3 grey white linear cores measures 1 2cm. entire tissue processed,section from the breast parenchyma shows infiltrating arranged in nests and sheets. the cells are round to oval hyperchromatic nuclei. scant to moderate cytoplasm. admixed lymphocytic infiltrate seen. mitosis 4 5 10 hpf.,left breast lesion biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1810934,right breast lump possibility of carcinoma breast.,biopsy from right breast lump,received 3 grey white linear cores measures 1.5 2cm. entire tissue processed.,section shows cores of breast parenchyma many ducts showing ductal carcinoma in situ comedo and solid type with few foci of invasive carcinoma in sheets and nests. the cells show increased n c ratio moderate cytoplasm. pleomorphic hyperchromatic nuclei. mitosis is increased.,biopsy from right breast lump:invasive carcinoma with extensive ductal carcinoma in situmodified bloom richardson score is 8 9 grade 3.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR1810956,case of right breast carcinoma.,a) right breast wide excisionb) right axillary clearancec) left breast lumpectomy,a) received lumpectomy specimen 8x8x3.8cm.skin ellipse measures 6.5x1.5cmon serial section fibrotic area measures 1x0.5x0.5cmdistance from margins:superior margin : 2.5cminferior margin : 1.2cmmedial margin : 2.3cmlateral margin : 4.5cmdeep margin : 3.7cmb) received fibrofatty tissue measures 8x6x5cmlargest lymph node measures 2x1x1cmcut surface fatty infiltration.c) received globular mass measures 3x2x1cmexternal surface irregularcut surface solid grey white slit like spaces seen.,a) section studied shows breast parenchyma with ducts of varying sizes lined by inner epithelial layer and an outer intact myoepithelial layer. the stroma shows areas of hyalinisation edema and periductal inflammatory aggregates. no evidence of atypia malignancy noted in the material submittedc) section studied show breast parenchyma with a well circumscribed lesion comprising of proliferating glandular and stromal elements which distorts and compreses the ducts in the centre. the ductules towards the pariphery are dilated. they are lined by inner ephithelial and an outer intact myoepithelial layer. stroma are few scattered lymphomononuclear cell infiltrate. no atypia malignancy is noted.,a) right breast wide excision post nact:small focus of periductal atypical cells are seen in frozen section however no evidence residual viable tumor seen in the deeper paraffin sectionsno ductal carcinoma in situ is seenall margins ( superior inferior medial lateral and deep ) are free of tumorb) right axillary clearance:isolated all fourteen lymph nodes are free of tumor (0 14)c) left breast lumpectomy:feature favor selerosing adenosis no evidence of atypia malignancy noted in the material submitted.
MR1810968,left breast carcinoma,a) left modified radical mastectomyb) level 3 nodes.,a)received in : formalin procedure : modified radical mastectomy post nact laterality :lefttotal dimensions : medial to lateral :19cm superficial to deep : 7cm superior to inferior : 14cmskin ellipse :14.5x9cmnipple :normal scar surgical defect : not seentumor :single tumor size : 3.2x1.5x1.5cm location of tumor : upper outer quadrantmargins of tumor : irregulardeep margin : 1.0cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail : 14x6.5x1msize of largest node :3x2x1cm cut surface grey brown.b) received received fibrofatty tissue measures 3.5x2.5x1cm.largest measures 0.5cm.,tumor bed :residual viable tumor present consisting of clumps groups and ducts of pleomorphic cells with hyperchromatic nucleus focal areas of calcification and fibrosis present,a) left modified radical mastectomy post nacthistological type: residual viable invasive ductal carcinomagrade :3tumor component maximum dimension 3.2cm.invasive component measures 2.2cm.ductal carcinoma in situ measures 1cm.modified bloom richardson score is 8 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3ductal carcinoma in situ present cribriform and comedonecrosislymphovascular invasion presentperineural invasion presentposterior resection margin is is free of tumor.nipple and areola is unremarkable.level i and ii nodes 2 nodes show metastatic deposits of the out of 11 nodes perinodal spread present.b) level iii 5 nodes no deposit of tumorpathological stage ypt2n1summary:residual viable tumor present left breast grade :3.level i and ii nodes 2 nodes show metastatic deposits of the out of 11 nodes perinodal spread present.level iii 5 nodes no deposit of tumor
MR1810969,right breast lump fibroadenoma,biopsy from right breast lump.,received 8 grey white linear cores measures 0.5 1.3cm. entire tissue prominence.,section shows case of breast with few composed and elongated ducts with presenced epithelial and myoepithelial layers surrounded by abundant stroma with variable cellularity composed of spindle cells with luminal atypial and hyalinisation. no evidence of in situ or invasive carcinoma in section examined.,biopsy from right breast lump:suggestive of fibroadenoma with cellular stroma
MR1810995,left breast lump carcinoma breast,biopsy from left breast lump.,received 3 grey white linear cores measures 0.2 1.5cm. entire tissue processed,section shows cores of fibrocollagenous tissue harboring an invasive neoplasm in nests cords and tubules with cells showing moderate cytoplasm hyperchromatic nuclei with moderate pleomorphism and increased mitosis. stroma is desmoplastic. areas of ductal carcinoma in situ also noted. areas of necrosis.,biopsy from left breast lump:invasive carcinoma (nst)modified bloom richardson score is (3+2+2)7 9.
MR1811000,right breast lump carcinoma breast.,biopsy from right breast lump.,received 5 grey white linear cores measures 1.5 2cm. entire tissue processed.,section shows multiple fragments of breast parenchyma harboring infiltrating lesion arranged in sheets. the cells are oval to spindle with hyperchromatic nuclei and moderate cytoplasm. multinucleated cells tumor tumor giant cells noted. stroma is myxoid. lymphoplasmacytic infiltrate seen. mitosis are seen.,biopsy from right breast lump:high grade malignancy.possibiltiy considered are 1. malignancy phylloides.2. metastatic carcinoma.
MR1811006,left breast lump carcinoma breast,left breast lump biopsy,received 4 grey white linear cores measures 1.5 2cm. entire tissue processed,section shows multiple cores of infiltrative neoplasm arranged in sheets and nests. the cells are round to oval hyperchromatic nuclei and scant to moderate amount of cytoplasm. admixed lymphocytes infiltrates seen. areas of necrosis noted. mitosis 5 6 10 hpf.,left breast lump biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 7(3+2+2).
MR1811036,left brest lump carcinoma breast,biopsy from left breast,received 4 grey white linear cores measures 2 2.5cm. entire tissue processed.,section show multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets and nests. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm cells exhibit moderate nuclear pleomorphism. stroma shows desmoplasia. mitosis are 5 6 10 hpf.,biopsy from left breast:invasive ductal carcinoma grade 2modified bloom richardson score is 3+2+2 7 9.ductal carcinoma in situ ( cribriform type ) with intermediate nuclear grade.
MR1811099,left breast lump recurrent carcinoma left breast.,left breast lump core biopsy.,received multiple grey white linear cores measures 0.8 to 1.2cm. entire tissue processed.,the sections shows linear cores of breast parenchyma showing infiltration by tumor arranged in nests cores and focal tubules. the tumor cells are pleomorphic round to ovoid with high n:c ratio hyperchromatic round to ovoid nuclei and moderate to scant cytoplasm. intervening stroma is desmoplastic.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1811100,left breast lump carcinoma breast,biopsy from left breast lump,received 4 grey white linear cores 1.5 2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged predominantly in nests. the cells are large having abundant amount of pale eosinophilic cytoplasm pleomorphic hyperchromatic nucleus and prominent nucleoli. stroma shows desmoplasia. occasional mitotic figures are discerned.,biopsy from left breast lump:invasive carcinoma nst grade 2modified bloom richardson score 6 9( 3+21).
MR1811108,right breast lump carcinoma breast.,biopsy from right breast lump,received 8 grey white linear cores measures 1 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a few atypical cell clusters with hyperchromatic nuclei and moderate cytoplasm. the lesional cells are floating in lakes of mucin.,biopsy from right breast lump:invasive carcinoma with mucinous areas.
MR1811113,carcinoma breast.,biopsy from left breast.,received 5 grey white linear cores measures 1 2.5cm. entire tissue processed.,section shows linear cores of fibrous tissue harboring an infiltrating cellular lesion arranged in nests cores and vague tubules. the cells are ovoid having abundant amount of pale eosinophilic cytoplasm hyperchromatic nucleus and prominence nucleoli. mitotic figures are discerned. stroma is desmoplastic.,biopsy from left breast:invasive carcinoma nst grade 2modified bloom richardson score is 7 9( 3+2+2).
MR1811126,muo of unknown origin primary breast primary lung.,biopsy from cervical lymph node,received 2 lymph nodes largest lymph node measures 2x0.8x0.6cm. entire tissue processedcut surface grey white.,section from lymph node shows completely effaced architecture and replaced by a lesion arranged in lobules separated by thick and thin fibrous septa. within the lobules are seen neoplastic cells arranged in closely packed nests. the cells are large with distinct cell borders pleomorphic round vesicular nucleus prominent 1 2 nucleoli an abundant clear to eosinophilic cytoplasm. interspersed hyaline globules are noted.,biopsy from cervical lymph node:metastatic adenocarcinoma most likely from lung.
MR1811186,carcinoma right carcinoma,a)right breast conservation surgery post nactb) right sentinel lymph node biopsyc) completion axillary dissection.,a) received lumpectomy specimen measures 6x4x0.6cm skin ellipse measures 2.5x0.8cmcut surface identified a grey white fibrotic area measures 0.6x0.6x0.5cm. distance from margins:super margins : 0.4cminferior margin : 0.6cmmedial margin : 0.6cmlateral margin : 1cmdeep margin : 3cmb) received fibrofatty tissue measures 3x2x1cm.largest measures 0.8x0.7x0.6cm. cut surface grey white.c) received single fibrofatty tissue measures 10x6x0.5cmlargest lymph nodes measures 0.5x0.5x0.3cm.,section studied show breast parenchyma with stromal edema hyalinisation and fibrosis. interspersed are congested blood vessels with lymphomononuclear infiltrate.,a)right breast conservation surgery post nact:no residual viable tumor seen.b) right sentinel lymph node biopsy:isolated three lymphnodes are free of tumor (0 3)c) completion axillary dissection:isolated nine lymph nodes are free of tumor (0 9)
MR1811205,left breast lump possibility of carcinoma breast,biopsy from left beast.,received 5 grey brown linear cores measures 1.5 2cm. entire tissue processed,section shows linear cores of fibrocollagenous tissue harboring an infiltrating lesion arranged in sheets and nests. the cells are ovoid having abundant pale eosinophilic cytoplasm hyperchromatic pleomorphic nucleus with prominent nucleoli in few .mitotic figures are discerned. stroma is desmoplasia with dense lymphomononuclear cell infiltrate. areas of hemorrhage and necrosis seen.,biopsy from left beast:invasive carcinoma nst grade 2modified bloom richardson score is 6 9(3+2+1).
MR1811259,left breast lump carcinoma breast.,biopsy from left breast.,received grey white linear core measures 1.5 2cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring large dilated ducts lined by stratified round to oval cells overlying entire duct luminally. the cells have hyperchromatic nuclei and moderate cytoplasm. few ducts are showing clear punched out spaces. few showing comedo necrosis. all the ducts are lined by myoepithelial cells abluminally. stroma shows lymphocytic infiltrate.,biopsy from left breast:ductal carcinoma in situ ( cribriform and comedo type) intermediate nuclear grade.no invasive component seen.
MR1811260,right breast birads iv b lesion.right axillary node metastatic deposits probably from breast.,right breast core biopsy.,received multiple grey white linear cores measures 1.2 to 2cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1811261,right breast lump possibility of carcinoma breast.,biopsy from right breast lump biopsy.,received 5 grey white linear cores measures 1 2.5cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets and nests. the cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. stroma shows desmoplasia. mitosis 3 4 10 hpf.,right breast lump biopsy:invasive ductal carcinoma nos grade 2modified bloom richardson score is 6 9(3+2+1)
MR1811285,lump right breast.right breast lump carcinoma breast.,right breast lump.,received multiple grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic arranged in sheets. the cells have round hyperchromatic nucleus and moderate cytoplasm. also noted are ductal carcinoma in situ component (solid pattern). moderate nuclear pleomorphism noted. mitoses discerned.,right breast lump core biopsy : invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1811392,left breast lesion carcinoma breast.,biopsy form left breast.,received 4 grey white linear cores measures 1 1.5cm.,section shows multiple cores of breast parenchyma showing extensive lesion with neoplastic lesion in sheets. the cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. lymphoplasmacytic infiltrate seen. mitoses 2 3 10hpf.,biopsy form left breast:extensive necrosis with clusters of dysplastic ductal cells.no invasion is discerned.suggest repeat biopsy.
MR1811399,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores linear cores 1 1.5cm. entire tissue processed.,section shows multiple cores of breast parenchyma showing few benign ducts and cellular stromal lesion comprising of spindle cells having hyperchromatic nuclei nuclei moderate cytoplasm. stroma is myxoid. mitosis are 3 4 10 hpf.,biopsy from left breast lump:fibroepithelial biphasic neoplasm.favoring phyllodes tumor borderline categorysuggest wide excision for further confirmation.
MR1811419,case of left neck swelling,biopsy from left supraclavicular lymph node.,received 4 grey white linear cores measures 0.3 1cm. entire tissue processed.,section shows fragments of fibrocollagenous tissue harboring an invasive neoplasm in nests composed of cells with moderate cytoplasm pleomorphic hyperchromatic nuclei with crush artifacts.,metastatic carcinomatous deposit:possible primary1. breast2. aero digestive tract.
MR1811420,carcinoma breast.,biopsy from right breast lesion.,received multiple grey white linear cores measures 2 2.5cm.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets nests and cords. the cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. mitoses 10 12 10hpf. stroma shows desmoplasia.,biopsy from right breast lesion:invasive carcinoma nst grade lll.modified bloom richardson score is 8 9 (3+2+3)
MR1811426,right breast lump carcinoma breast.,right breast lump core biopsy.,received 4 grey white linear cores 2 2.5cm. entire tissue processed.,section from the breast parenchyma shows infiltrating neoplasm arranged in sheets and nests. the neoplastic cells are round to oval hyperchromatic cell are round to oval hyperchromatic nuclei abundant eosinophilic cytoplasm. cells are lying in the pools of extracellular mucin. admixed lymphocytes noted. mitosis 3 4 10 hpf.,right breast lump core biopsy:invasive carcinoma with mucinous features. modified bloom richardson score is 6(3+2+1).
MR1811433,carcinoma right breast.,a) right breast conservative surgery post nact.b) axillary lymph node dissection.,a) received skin fibrofatty tissue measures 7.5x7x3.5cm. skin ellipse measures 2.5x1cm. cut surface shows illdefined grey white firm area with clip in situ measures 1x0.8x0.5cm.distance from the margins:superior margin 2cm.inferior margin 1.5cm.medial margin 3cm.lateral margin 4cm.deep margin 1.5cm.b) received fibrofatty tissue measures 9x7x4cm.largest lymph node measures 2.5x1.5x1cm.,the sections show breast parenchyma showing marked areas of hyalinisation and fibrosis. no residual tumor identified.adjacent breast shows adenosis.margins are free of tumor.,a) right breast conservative surgery post nact:no viable residual tumor identified post nact status.superior inferior medial lateral and deep margins are free of tumor.b) axillary lymph node dissection.lymph nodes : 18 lymph nodes metastasis 0 (0 18).show treatment related changes.pathological grade : ypt0n0.summary:no viable residual tumor. right breast
MR1811480,right breast lump carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measures 2 2.5cm. entire tissue processed.,linear cores of breast parenchyma harboring a neoplasm arranged as islands and clusters. the neoplasm cells exhibit nuclear hyperchromasia and moderate cytoplasm. crush artifacts noted.,biopsy from right breast:invasive carcinoma nst.modified bloom richardson score 7 9 grade 2tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1811481,carcinoma left breast.,a) left breast conservative surgery post nactb) revised deep margin.c) left axillary clearance.,a) wide excision specimen measures 6.3x6x4cm.skin ellipse measures 3x0.4cmsmall fibrotic area measures 0.5x0.5x0.4cm.no obvious tumor identifieddistance from margins:superior margin :2.1cminferior margin :2cmmedial margin : 1.8cmlateral margin : 2.2cmdeep margin :2.1cm.b) received fibrofatty tissue bits measures 3x3x0.5cm.c) received multiple fibrofatty tissue measures,a) section studied shows breast parenchyma with tiny focus showing solid and comedonecrosis pattern of ductal carcinoma in situ. no obvious invasionis seen. focal areas of lymphomononuclear infiltrate are seen.,a) left breast conservative surgery post nact:residual viable tumor showing ductal carcinoma in situ solid and comedonecrosis pattern.no invasion identified.ductal carcinoma in situ measures 0.8cm in greatest dimension.lymphovascular invasion and perineural invasion are not seen.deep margin shows ductal carcinoma in situ. all margins of resection ( superior inferior medial and lateral ) are free of tumor.b) revised deep margin: free of tumorc) left axillary clearance:isolated all thirteen lymph nodes are free of tumor.
MR1811486,right breast lump p o carcinoma breast.,biopsy from right breast lump.,received 3 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets and nests. the cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism.,biopsy from right breast lump:invasive carcinoma nst grade 2.modified bloom richardson score 7 9 (3+2+2).
MR1811614,left breast lump carcinoma breast.,biopsy from left breast lump,received 4 grey white linear cores measures 1.5 2cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in nests cords and tubules. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. stroma shows desmoplasia mitosis 4 5 10 hpf.,biopsy from left breast lump:invasive carcinoma nst grade 2modified bloom richardson score is 6 9(3+2+1).
MR1811642,carcinoma left breast.,a) wide local excision biopsy left breast. b) sentinel lymphnode biopsy.c) sentinel lymph node biopsy.,a) wide local excision biopsy left breast : received lumpectomy measures 6x6x3cm. skin measures 4.5x2cm. cutsurface show grey white tumor measures 1.3x1.2x1cm. distance from margins : superior margin : 1 cm.inferior margin : 2 cm.medial margin : 1 cm.lateral margin : 1.5 cm.deep margin : 0.1 cm.b) sentinel lymphnode biopsy : received single lymph node measures 1.5x1x1cm. cutsurface fatty infiltration. c) sentinel lymph node biopsy : received isolated lymphnode measures 1x0.5x0.5cm. cutsurface unremarkable. entire tissue processed.,a) section studied shows breast parenchyma harboring an infiltrating lesion arranged in nests and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma is desmoplastic with dense lymphomononuclear cell infiltrate.,a) wide local excision left breast. invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9.tubule formation : 2nuclear pleomorphism : 3mitotic figures : 2 .............. 7 9 ...............tumor measures 1.3cm in greatest dimension.invasive component measures 1.3cm. ductal carcinoma in situ not seen. lymphovascular invasion perineural invasion are not identified. all margins of resection (superior inferior medial lateral and deep) are free of tumor. b) sentinel lymph node biopsy : isolated single lymphnode is free of tumor (0 1)c) sentinel lymph node biopsy : isolated two lymphnode are free of tumor (0 2).pathological stage : pt1pno.
MR1811652,right breast mass.,biopsy from right breast.,received 5 grey white linear core measures 1 to 1.5cm.,linear cores of breast tissue infiltrated by a neoplasm arranged as clusters and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. tumor cells are seen floating in lakes of mucin.,biopsy from right breast. invasive carcinoma with mucinous areas.grade 2. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 ...........
MR1811660,large ill defined hypoechoic lesion with skin ulceration left breast,biopsy from left breast lesion.,received 6 grey white soft tissue bits measures 0.8x0.5x0.3cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets nests and singly scattered. the cells are round to oval having hyperchromatic nuclei moderate cytoplasm. stroma shows desmoplasia and hyalinisation. occasional mitosis seen.,biopsy from left breast lesion:suggestive of invasive carcinoma nuclear grade 2
MR1811676,case of left breast carcinoma.,a) blue node left sentinel node biopsy. .b) hot node left sentinel node biopsy. c) left breast wide excision.,a) received single fibrofatty tissue measures 1.5x1.0x0.5. isolated one lymph node measures 1x0.8x0.5cm. b) received multiple fibrofatty tissue measures 1.5x1.5x1.0cm. largest lymph node measures 1x0.5x0.5cm. isolated two lymphnode. c) received single skin covered fibrofatty tissue measures 7.5x6x3cm. cut surface shows ill defined grey white lesion measures 2.2x1.8x1.5cm. distance from margins :superior margin : 1cm.inferior margin : 1.5 cm.medial margin : 1.5 cm.lateral margin : 1.2 cm.deep margin : 0.4 cm.,sections studied show breast parenchyma harboring an infiltrating lesion arranged in nests sheets and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with areas of hemorrhage and necrosis. interspersed lymphomononuclear cell infiltrates are seen.,a) blue node left sentinel lymphnode biopsy : isolated single lymphnode is free of tumor (0 1)b) hot node left sentinel node biopsy : isolated two lymphnode are free of tumor (0 2)c) left breast wild local excision :invasive ductal carcinoma grade 2. tumor measures 2.2cm in maximum dimension modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 ................. 7 9 .................lymphovascular invasion perineural invasion are not identified.all margins (superior inferior medial laterality and deep) are free of tumor. pathological grade : pt2no.
MR1811694,right breast malignant,right breast biopsy.,received six grey white linear cores measures 1 1.5 cm. entire tissue processed.,section show multiple fragments of breast tissue harboring a neoplasm arranged in sheets and nests. the cells are round to oval vesicular nuclei abundant eosinophilic cytoplasm. adjacent lymphoplasmacytic infiltrate noted. mitotic 5 6 10 hpf.,right breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1811742,right breast lesion birads i,biopsy from right breast lump,received multiple grey white linear cores cores measures 1.5 2cm. entire tissue processed.,section show multiple cores of breast parenchyma harboring infiltrating lesion arranged in cords and nests. the ells are round to oval having hyperchromatic nuclei and moderate cytoplasm. stroma shows desmoplasia. occasional mitosis are seen.,biopsy from right breast lump:invasive carcinoma nst nuclear grade 2.
MR1811756,right breast retroareola lump carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measures 2 2.5cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring lesion arranged in cords nests and sheets. the lesional cells are round to oval having hyperchromatic nuclei and moderate cytoplasm mitosis 5 6 10 hpf. stroma shows desmoplasia.,biopsy from right breast:invasive carcinoma nst grade 2.modified bloom richardson score is 7 9(3+2+2).
MR1811759,left breast lump carcinoma breast.,biopsy from left breast lump,received 4 grey white linear cores measures 1.5 2.5cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in nests an cords. the cells lesional cell are round to oval having hyperchromatic nuclei and moderate cytoplasm. stroma shows desmoplasia . occasional mitosis seen. solid ductal carcinoma in situ seen.,biopsy from left breast lump:invasive carcinoma nst grade 2.modified bloom richardson score is 6 9(3+2+1).
MR1811775,left breast mass.,left breast mass biopsy.,received three grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in tubules cords and nests. the cells have round hyperchromatic nuclei inconspicuous nucleoli and moderate cytoplasm.,left breast mass biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1811778,carcinoma right breast.,a) right modified radical mastectomy post nact.b) level 3 nodes.c) revised superior margin.,a) received in : 10 nbf.procedure : right modified radical mastectomy post nact.laterality : right.total dimensions : medial to lateral 17cm superficial to deep 5cm superior to inferior 15cm.skin ellipse : 13x11cm. nipple : normal scar surgical defect : absent.tumor : single.tumor size : 3x3x2.5cm. cut surface is cystic and hemorrhagic also seen granular and papillary areas.location of tumor : upper inner quadrant.margins of tumor : illdefined.deep margin : 2.5cm. muscle : 4.5x3.5cm.adjacent breast : fibrofatty tissue. axillary tail : 10x8x3cm.cm.size of largest node : 2.5x2x2cm. cut surface fatty infiltration seen.b) received single fibrofatty tissue measures 2x2x1cm. entire tissue processed.c) received single fibrofatty tissue measures 4.5x0.5x0.5cm. entire tissue processed.,the sections from breast parenchyma show tumor infiltrating in sheets nests and islands showing large areas of necrosis. the tumor cells are round to polygonal with increased n:c ratio enlarged highly pleomorphic nuclei prominent nucleoli and moderate amount of eosinophilic cytoplasm. numerous tumor giant cells are identified. areas of tumor nests having central vascular cores are seen. suggestive of papillary pattern. focal comedo type ductal carcinoma in situ is seen.,a) right modified radical mastectomy post nact.histological type: viable invasive ductal carcinoma nst. possibility of solid papillary carcinoma to be ruled out. grade: 3tumor measures maximum dimension 3cm.invasive component measures 2.8cm.ductal carcinoma in situ measures 0.2cm.modified br score is 8 9tubule formation: 3nuclear pleomorphism: 3mitotic figures: 2ductal carcinoma in situ is comedo type.lymphovascular invasion is not identified.perineural invasion is identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: 21 lymph nodes metastasis 0 (0 21).b) level 3 nodes:3 lymph nodes isolated are free of tumor (0 3).c) revised superior margin:free of malignancy.pathological stage: pt2n0summary: viable invasive ductal carcinoma nst right breast.tumor grade: 3lymph nodes : 24 lymph nodes isolated are free of tumor (0 24).
MR1811781,left breast mass malignant.,left breast lump biopsy.,received 5 grey white linear core measures 1 2cm. entire tissue processed,section show multiple cores of breast parenchyma showing normal ducts lined by cuboidal cells luminally and myoepithelial cells abluminally with interspersed lymphocytes and plasma cells in stroma.,left breast lump biopsy :suggestive of invasive carcinoma with lobular features.
MR1811793,carcinoma left breast.,a) lumpectomy b) left modified radical mastectomy post lumpectomy specimen.,a) lumpectomy:received unoriented fibrofatty tissue measures 6x4.5x3cm. cut surface shows retractive well defined grey white firm lesion measures 3x2.5x2.5cm.nearest inked margin is 1.5cm away. b) modified radical mastectomy :received in : formalin.procedure : left modified radical mastectomy. laterality : left breast. total dimensions : medial to lateral : 18cm. superficial to deep : 5 cm. superior to inferior :18cm.skin ellipse :15x7cm.nipple : retracted. surgical defect : seen measures 6cm. 0.5cm medial from nipple areola. tumor : lumpectomy bed measures 6x4.5x3cm. location of lumpectomy bed : upper inner quadrant lower inner quadrant. deep margin from lumpectomy bed : 1 cm. adjacent breast : fibrofatty. axillary tail : 6.5x5x3cm. size of largest node : 2x1.5x1cm. cutsurface grey white.,a)lumpectomy specimen left breast:tumor bed: tumor is harboring pleomorphic oval to polygonal cells present in diffuse sheets and clumps. the cells show vesicular to hyperchromatic nucleus scanty cytoplasm. between the clumps of cells focal areas of necrosis is present.histological type: invasive ductal carcinoma grade ii.tumor measures 3cm in maximum dimension invasive component measures 3cm.ductal carcinoma insitu is not identified.modified br score is 7 9tubule formation:3nuclear pleomorphism: 2mitotic activity:2lymphovascular and perineural invasion is not identified.b)left modified radical mastectomy post lumpectomy,tumor bed : shows fibrofatty tissue with focal hemorrhagic areas. no evidence of residual tumor present.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes : 14 lymph nodes metastasis : 0pathological stage: pt2n0 (as tumor is measuring 3cm in lumpectomy specimen) summary : lumpectomy shows invasive ductal carcinoma grade ii. lymphnode status : modified radical mastectomy specimen shows 14nodes.no deposits of tumor (0 14)
MR1811844,birad v lesion in right breast.,biopsy from right breast.,received grey brown linear core measures 1 to 1.2cm. entire tissue processed.,section from the breast parenchyma shows infiltrating neoplasm arranged in tubules sheets and nests. the cells are round to oval hyperchromatic nuclei abundant eosinophilic cytoplasm. admixed lymphoplasmacytic infiltrate. intratubular mucin filled. mitotic figures are noted.,biopsy from right breast:invasive carcinoma with mucinous features grade 1.modified bloom richardson score (2+1+1) 4 9
MR1811868,left breast lump carcinoma breast.,biopsy form left breast lump.,received 3 grey white linear cores measures 1 to 2cm. entire tissue processed.,sections from breast parenchyma with infiltrating neoplasm arranged in sheets and nests. the cells forming the lesion are round to oval hyperchromatic nuclei scant to moderate cytoplasm. admixed lymphoplasmacytic infiltrate. mitotic figures are noted.,biopsy form left breast lump:invasive carcinoma of ductal origin nst nuclear grade 2.modified bloom richardson score (3+2+2) 7 9.
MR1811881,right breast carcinoma.,a) right breast right breast conservation surgery.b) right sentinel lymph node(hot node).c) right sentinel lymph node(blue and hot node).d) revised inferior margin.e) right axillary clearance.,a) received skin covered soft tissue bits measures 9x5x3cm. skin ellipse measures 6.5x1.0cm. surface of skin is unremarkable. cut surface shows grey white firm tumor measures 2.5x2x2cm. distance from the margins:superior margin 1.2cm.inferior margin 0.8cm.medial margin 1.0cm.lateral margin 1.5cm.deep margin 1.0cm.b) received multiple fibrofatty tissue measures 2.5x2x1.5cm. largest lymph nodes measures 2x1x1cm. cut surface shows grey white deposit.c) received single lymph node measures 0.5x0.5x0.5cm.d) received single fibrofatty tissue tissue measures 4x2.5x1cm. cut surface shows unremarkable.e) received fibrofatty tissue measures 8x5x1.5cm. largest lymph node measures 1.5x1x0.5cm.,section shows breast paranchyma harboring an infiltrating neoplasm arranged in sheets cords nests with intervening fibrous septa and tubules. the cells have round vesicular nucleus prominent nucleoli and moderate cytoplasm. ductal carcinoma in situ is present. (solid comedo pattern).,a) right breast right breast conservation surgery:invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic activity 2 tumor measures 2.5 cm in greatest dimension. ductal carcinoma in situ of solid comedo pattern with intermediate nuclear grade. lymphovascular invasion is identified. perineural invasion is not identified. all resected margins are free of tumor.b) right sentinel lymph node(hot node):one out of two lymph nodes show metastatic tumor deposit(1 2). size of the tumor deposit measures 0.6 cm in greatest dimension. extranodal extension is not seen.c) right sentinel lymph node(blue and hot node):one lymph node isolated negative for malignancy (0 1).d) revised inferior margin: free of tumor.e) right axillary clearance:seventeen lymph nodes isolated negative for malignancy(0 17).
MR1811924,left breast lump.,biopsy from left breast.,received 4 grey white linear cores measures 0.5 to 1.5cm. entire tissue processed.,section shows infiltrating neoplasm arranged in sheets and nest. the cells are large pleomorphic hyperchromatic nuclei scant cytoplasm. admixed lymphocytic infiltrates. atypical mitotic figures noted.,biopsy from left breast:invasive carcinoma nst nuclear grade 2.modified bloom richardson score is (3+2+2) 7 9.
MR1811926,known case of carcinoma right breast post mrm,biopsy from left breast.,received 4 grey white linear cores measures 1.5 2cm. entire tissue processed.,section from the breast parenchyma show atypical epitheial cells which are round to oval hyperchromatic nuclei clear cytoplasm. adjacent stroma shows hyalinisation adenosis and fibrosis.,biopsy from left breast:features highly suspicious of invasive carcinomaas the tissue is scanty suggest repeat biopsy for conclusive opinion and ihc.
MR1812017,right breast lump birads v.,right breast lesion core biopsy.,received 5 grey white linear cores measures 1 2cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrating by neoplastic cells arranged in sheets and nests. the cells have pleomorphic round to oval hyperchromatic nuclei and moderate amount of cytoplasm. mitosis is discerned.,right breast lesion core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1812058,left breast lump birads v lesion cyst breast,left breast core biopsy.,received 5 grey white linear cores measures 1 2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating neoplasm arranged in nests tubules and sheets. the cells have pleomorphic round hyperchromatic nuclei prominent nucleoli and moderate cytoplasm. mitosis is discerned. occasional bizarre nuclear forms are noted.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score 7(3+2+2).
MR1812095,right breast mass carcinoma right breast.,right breast mass biopsy.,received 3 grey brown linear cores measures 1.5 2cmn. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in sheets and cords. the cells have round hyperchromatic nucleus inconspicuous nucleoli and moderate amount of clear to eosinophilic cytoplasm. mitosis is discerned.,right breast mass biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1812118,right breast lump carcinoma breast.,biopsy from right breast lump.,received grey white 4 linear cores measures 1.5 to 2cm. entire tissue processed.,section shows cores of fibro adipose tissue harboring an invasive neoplasm in nested pattern composed of cells with moderate to abundant eosinophilic cytoplasm hyperchromatic nuclei with marked pleomorphism and increased mitosis. intra and peritumoral lymphoplasmacytic aggregates are noted.,biopsy from right breast lump:invasive carcinoma nos.modified bloom richardson score is 7 9 (2+3+2) grade ii.
MR1812128,right breast lesion carcinoma breast,biopsy from right breast lesion,received 5 grey white linear cores measures 1.5 2cm. entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as clusters and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma shows areas of necrosis,biopsy from right breast lesion:invasive ductal carcinoma.grade 2
MR1812146,right breast lump with distribution nipple carcinoma right breast.,right breast biopsy.,received 2 grey white linear cores measures 0.8 1.5cm. entire tissue processed.,section show linear cores of fibrocollagenous tissue with extensive hyalinisation. no viable tumor cells seen.,right breast biopsy:shows extensive hyalinisation.no viable tumor cells seen.comment : deeper sections have been studied.
MR1812150,left breast lump carcinoma breast,biopsy from left breast lump,received 4 grey white linear cores measures 1 1.5cm. entire tissue processed,section from the breast parenchyma with infiltrating neoplasm arranged in sheets and nests. the cells are large round to oval hyperchromatic nuclei. scant to moderate cytoplasm. adjacent stroma shows lymphoplasmacytic infiltrate noted. mitosis 3 10 hpf.,biopsy from left breast lump:invasive carcinoma nst nuclear grade 2modified bloom richardson score is (3+2+1)6 9.
MR1812156,left breast lump carcinoma breast.,biopsy from left breast lump,received multiple grey white linear cores measures 1 2cm. entire tissue processed.,section studied shows linear cores of fibrous tissue harboring an infiltrating cellular lesion arranged in nests cords and vague tubules. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned ( 7 8 10 hpf ) stroma is desmoplastic with moderately dense lymphomononuclear cell infiltrate.,biopsy from left breast lump:invasive carcinoma nst grade2modified bloom richardson score is 7 9(3+2+2).
MR1812168,left breast lesion.,biopsy from left breast.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of breast parenchyma infiltrated by lesion arranged in nests cord trabecular pattern lesional cells are large with marked pleomorphic round to oval hyperchromatic nuclei inconspicuous nucleoli moderate amount of granular eosinophilic cytoplasm. mitotic figures (3 4 10hpf) are discerned. stroma shows desmoplasia with mild lymphocytic infiltrate.,biopsy from left breast:invasive carcinoma nst grade 2.modified bloom richardson score is 6 9.tubular formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1812183,suspected hypo echoic lim in right breast at 10 11 0 clock position neoplastic.,right breast lesion biopsy.,received 4 grey white linear core measures 0.4 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in cords and tubules. cells have pleomorphic round hyperchromatic nuclei with moderate cytoplasm. surrounding stroma shows desmoplasia. mitosis is discerned.,right breast lesion biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1812185,left breast mass.,left breast mass core biopsy.,received 3 grey white linear core measures 0.5 to 1.5cm. entire tissue processed.,section shows tumor cells in diffuse sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1812206,left breast mass birads iv lesion carcinoma breast.,biopsy from left breast mass,received multiple grey white linear cores measures 0.3x0.2x0.1cm. entire tissue processed,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets and nests. the lesional cells are round to oval having dark nuclei and moderate cytoplasm. cells exhibit mild nuclear pleomorphism. stroma shows desmoplasia. occasional mitosis are seen.,biopsy from left breast mass:invasive carcinoma nstmodified bloom richardson score is 5 9tubule formation 3nuclear pleomorpism 1mitotic figures 1 5 9
MR1812236,carcinoma breast.,bronchial biopsy.,received multiple grey white to grey brown soft tissue bits altogether measures 0.5x0.4x0.2cm. entire tissue processed.,section studied show fibrous tissue with a tiny bit of bronchial epithelium harboring an infiltrating lesion arranged in nests. the cells are ovoid having moderate amount of cytoplasm hyperchromatic pleomorphic nucleus and prominent nucleoli. mitotic figures are discerned. stroma is desmoplastic with areas of hemorrhage and necrosis.,bronchial biopsy:adenocaricnoma. secondary from breast. primary.suggest ihc.
MR1812257,carcinoma left breast mass,left breast biopsy.,received 6 grey white linear cores measures 1 2cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in cords and nests. the cells have round nucleus dispersed chromatin and moderate cytoplasm. mitosis is discerned.,left breast biopsy:invasive carcinoma grade2. modified bloom richardson score is 6(3+2+1).
MR1812259,malignant left breast lump.,a) specimen of left hand nevus. b) specimen of left shoulder nevus. c) specimen of left breast wide local excision.,a) specimen of left hand nevus : received single skin covered soft tissue measures 1x0.8x0.6cm. skin surface shows nodule measures 0.5x0.5x0.4cm. cutsurface grey brown nodule and is 0.1cm. from distal resected margin. b) specimen of left shoulder nevus : received single skin covered soft tissue bits measures 2x0.6x0.4cm. skin surface shows black nodule in 0.6x0.6x0.1cm. nodule is 0.4cm away from distal resected margin. c) specimen of left breast wide local excision : received fibrofatty tissue with skin ellipse measures 8.5x6x6xcm. skin ellipse measures 6.5x2cm. cutsurface shows tumor measures 5.5x2.5x2cm. tumor is grey brown shows granular areas and hemorrhagic areas.distance from margins :superior margin : 1.5cm.inferior margin : 1 cm.medial margin : 0.1 cm.lateral margin : 1.5 cm.deep margin : 0.5 cm.,a) specimen of left hand nevus : sections studied from lesional tissue shows thinned out epidermis and dermis that harbors small nests of round to oval cells having eosinophilic cytoplasm vesicular nuclei there is abundant extracellular and intracellular melanin noted. stroma shows sclerosis around pilosebacuous glands b) specimen of left shoulder nevus :section studied from lesional tissue harbors stratified squamous epithelium with acanthosis and keratin cysts. lesion extends into the dermis. dermis and sub epithelium shows lymphomononuclear infiltrates and shows dense sclerosis. c) specimen of left breast wide local excision :section studied from lesional tissue harbors well circumscribed neoplasm surrounded by thick fibrous capsule with tumor cells forming lobules of varying sizes. the tumor cells are arranged in papillae and cribriform pattern. the cells are pleomorphic have scant cytoplasm and vesicular nuclei. foci of comedonecrosis and dystrophic calcification seen. the tumor cells infiltrate across the capsule in few foci. stroma shows desmoplasia with lymphomononuclear infiltrates.,a) left hand nevus biopsy : intradermal nevus.b) biopsy from left shoulder nevus. seborrheic keratosis. c) specimen of left breast wide local excision invasive papillary carcinoma. tumor measures 5.5cms in greatest dimension. lymphovascular invasion and perineural invasion not identified. medial and deep margin involved. superior inferior and lateral margins are free of tumor.
MR1812260,left breast carcinoma breast.,biopsy from left breast,received 4 grey white liner cores measures 1 1.5cm. entire tissue processed,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets nests. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm cells exhibit moderate nuclear pleomorphism stroma shows desmoplasia mitosis 5 6 18,biopsy from left breast:invasive carcinoma modified bloom richardson score is 7 9 grade 2tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1812287,carcinoma left breast.,a) wide local excision post nact.b) sentinel lymph nodes.,a) received wide local excision skin covered measures 12x4x8cm. skin ellipse measures 8x2.5cm. surgical defect cut section shows grey white illdefined lesion with areas of hemorrhage and necrosis measures 3x2.2x2cm. distance from the margins.superior margin 1.5cm.inferior margin 1.8cm.medial margin 1.5cm.lateral margin 1.8cm.deep margin 1.3cm.b) received 2 lymph nodes.largest measures 1.5x1x0.5cm.,residual viable tumor is present.showing extensive areas of ductal carcinoma in situ cribriform and comedo necrosis.focal areas of invasive ductal carcinoma in situ present.maximum dimension of tumor is 3cm.ductal carcinoma in situ measures 2.2cm.invasive ductal carcinoma measures 0.8cm.modified bloom richardson score is 7 9.tubular formation 3.nuclear pleomorphism 2.mitotic activity 2.lymphovascular invasion is not identified.perineural invasion is not identified.resected margins : superior inferior medial lateral and deep margins are free of tumor.,a) wide local excision post nact:maximum dimension of tumor is 3cm.residual viable tumor present.extensive ductal carcinoma in situ present measures 2.2cm with comedo necrosisinvasive ductal carcinoma measures 0.8cm.nuclear grade ii.lymphovascular invasion is not identified.perineural invasion is not identified.all resected margins are free from the tumor.b) sentinel lymph nodes:2 nodes. no deposit of tumor.
MR1812299,left breast mass carcinoma breast,biopsy from left breast mass.,received 4 grey white linear cores measures 0.3 0.5cm. entire tissue processed.,section studied show linear cores of breast parenchyma harboring ductal epithelial cells predominantly forming multi layering papillae nests and cribriforming. the cells have scant cytoplasm increased n c ratio overlapping nucleus coarse chromatin and inconspicuous nucleoli. stroma shows mixed inflammatory infiltrate.,biopsy from left breast mass:papillary neoplasm ( nuclear grade 2)requires wide excision of the specimen.
MR1812304,carcinoma right breast.,a) wide local excision of right breast lumpb) right sentinel node biopsy. c) revised superior margind) revised lateral margine) completion mastectomy,a) wide local excision of right breast lump: received skin covered soft tissue mass measuring 7.5x6x3.5cm. skin ellipse measures 5.5x2.5cm. surface of skin unremarkable. cutsurface shows a grey white firm lesion measuring 1.8x1.5x1.3cm. distance from margins :superior margin : 1.2 cm.inferior margin : 1.2 cm.medial margin : 1 cm.lateral margin : 1.3 cm.deep margin : 1 cm.b) right sentinel lymphnode biopsy : received multiple fibrofatty tissue all together measuring 2.5x2x1cm. isolated 3 lymphnodes. largest lymphnode measures 1.2x1x1cm. cut surface grey brown. c) :revised superior margin: received single fibrofatty tissue measuring 6.5x5x1.5cm. cut surface shows fibrous area measuring 1.5x1x1cm. d) revised lateral margin :received fibrofatty measuring 8.5x3.5x2cm. cut surface grey white firm fibrous areas measuring 1.5x1x1cm. entire tissue processed. e) completion mastectomy: received multiple unoriented fibrofatty bits altogether measuring 12x8.0x3cm. largest bit measures 11x4x3.5.,sections studied show breast parenchyma harboring an infiltrating lesion arranged in nests and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma is desmoplastic with extensive areas of ductal carcinoma in situ. interspersed are few lymphomononuclear cell infiltrate. adjacent breast parenchyma shows fibroadenosis and usual ductal hyperplasia.,a) wide local excision of right breast lump : invasive ductal carcinoma grade 2 modified bloom richardson score is 6 9 tubule formation : 3 nuclear pleomorphism : 2 mitotic figures : 1 ......... 6 9 .......... tumor measures maximum dimension : 1.8 cm. invasive component measures : 0.8 cm in greatest dimension. ductal carcinoma in situ measures :1cm in greatest dimension. extension ductal carcinoma in situ :solid cribriform and comedonecrosis pattern are identified. superior and lateral margins show ductal carcinoma in situ. all other margins (inferior medial and deep) are free of tumor. b) right sentinel lymph nodes. isolated three lymphnodes are free of tumor (0 3)c) revised superior margin : shows fibroadenosis and usual ductal hyperplasia. d) revised lateral margin. shows fibroadenosis and usual ductal hyperplasia. e) completion mastectomy nipple sparing. shows fibroadenosis. margin status cannot be ascertained. summary:breast conservative surgery :wide local excision of the right breast. total dimension of the tumor is :1.8x1.5x1.3cm. invasive ductal carcinoma measures :0.8cm. nuclear grade ii ductal carcinoma in situ measures :1cm. with comedonecrosis. lymphovascular invasion not identified revised superior revised lateral margin all other margins inferior medial and deep are free of tumor. right sentinel node 3 nodes no deposits of tumor. completion mastectomy :nipple sparing. no residual tumor present. shows breast parenchyma. margins cannot be ascertained.
MR1812405,carcinoma breast on tamoxifen.,biopsy from endometrium.,received multiple grey brown soft tissue bits measures 2x1x1cm. entire tissue processed.,sections show multiple fragments of endometrial tissue with normal gland to stromal ratio. the glands appear to be in early secretory proliferative phase with stroma showing focal edematous areas. areas of hemorrhage seen.,biopsy from endometrium:simple endometrial polyp with tamoxifen related changes.no evidence of malignancy in the material submitted.
MR1812457,left breast fibroadenoma,biopsy from left breast.,a) received 5 grey white linear cores measures 0.5 1cm. entire tissue processed.b) received 4 grey white linear cores measures 1 1.5cm. entire tissue processed.,a) section shows from the breast parenchyma shows a lesion with multiple dilated duct and composed by hyelinising stroma. ducts are lined by luminal and adluminal cells. adjacent stroma shows lymphocytes.b) section from the breast parenchyma shows a infiltrating lesion arranged in sheets the cells round to oval nuclei with scant cytoplasm. .adjacent stroma shows normal epithelial ductal cells lined by luminal and adluminal cells. the shows shows myxoid changes. admixed lymphocytic infiltrate noted.,a)biopsy from left breast:suggestive of fibroadenoma.no evidence of malignancy.b) left breast lesion on 9 clock position:suggestive of invasive carcinoma with lobular features nuclear grade 2.
MR1812469,speculated hypochronic in outer quadrant of rb neoplastic,biopsy from right breast lesion.,received 4 grey white linear cored measures 1.5 2cm. entire tissue processed.,section from the breast parenchyma shows infiltrating neoplasm arranged in sheets tubule and nests. the cells are round to oval hyperchromatic nuclei . scant to moderate cytoplasm. few with intranuclear inclusions noted. adjacent breast parenchyma shows. lymphocytic infiltrates. mitotic figures noted.,biopsy from right breast lesion:invasive ductal carcinoma grade 2modified bloom richardson score is (2+3+2).
MR1812500,carcinoma left breast.,a) left sentinel lymph node.b) left breast left mastectomy.,a) received 1 lymph nodes measures 0.8 x 0.5 x 0.5 cm.b) received in : formalin.procedure : mastectomy.laterality : left.total dimensions : medial to lateral 13cm. : superficial to deep 3cm. : superior to inferior 17cm.skin ellipse : 10x6cm.nipple : normal.scar surgical defect : absent.tumor : single.tumor size : 2.5 x 2.2 x 2 cm.location of tumor : lower outer quadrantmargins of tumor : ill defined.deep margin : 0.2cm.muscle : absent.adjacent breast : fibrofatty tissue.axillary tail : absent.received multiple fibrofatty tissue measures 2.5 x 2 x 2 cm. isolated 2 lymph nodes. largest lymph nodes measures 1.5x1x1cm. cut surface shows fatty infiltration.,section shows breast parenchyma shows an invasive neoplasm arranged in sheets and cords with extensive ductal carcinoma in situ component (solid cribriform) pattern of intermediate grade.,a) left sentinel lymph node:three lymph nodes isolated negative for malignancy (0 3)b) left breast left mastectomy:invasive ductal carcinoma grade 2.modified bloom richardson score 7 9.tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9 tumor measures 2.5cm in greatest dimension. ductal carcinoma in situ component is present of intermediate nuclear grade. (solid cribriform pattern). lymphovascular invasion is not identified. perineural invasion is not identified. posterior resected margin is free of tumor. nipple and aerola is unremarkable.lymph nodes:one lymph node identified negative for malignancy (0 1).
MR1812505,left breast lump carcinoma breast.,left breast lump.,received 3 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections from the breast parenchyma shows infiltrating neoplasm arranged in sheets indian file pattren and nest. the cells are large hyperchromatic nuclei scant cytoplasm. few with prominent nucleoli. adjacent breast show hyalinization and inflammatory cells. atypical mitotic figures are seen,left breast lump:invasive carcinoma nst with lobular features.nuclear grade 2.
MR1812507,right breast lump possibility of carcinoma breast,right breast core biopsy.,received 4 grey white linear cores measures 0.5 1cm. entire tissue processed.,section sows linear cores of breast parenchyma harboring an invasive neoplasm arranged in sheets. the cells have pleomorphic round to oval hyperchromatic nuclei with moderate cytoplasm. surrounding stroma shows mononuclear infiltrate and desmoplasia. mitosis is discerned.,right breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1812519,right breast lump possibility of carcinoma breast.,right breast lump biopsy.,received 3 grey white linear cores measures 1 2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in tubules sheets and cords. cells have pleomorphic round to oval irregular hyperchromatic nuclei few with prominent nucleoli and moderate cytoplasm. surrounding stroma shows desmoplasia. mitosis is discerned. atypical mitotic figures noted.,right breast lump biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1812536,right breast lump carcinoma breast,biopsy from right breast lump,received 4 grey white linear cores measures 0.8 1.5cm. entire tissue processed.,section from the breast parenchyma shows infiltrating neoplasm arranged in sheets and nests. the cells are round to oval vesicular nuclei prominent nucleoli scant to moderate cytoplasm. admixed lymphoplasmacytic infiltrates. occasional mitotic noted. areas of of hyalinisation seen.,biopsy from right breast lumpinvasive carcinoma (nst) grade 2modified bloom richardson score is 7 9(3+2+2)
MR1812583,left breast lump p o carcinoma breast.,left breast lump.,received 3 grey white linear cores measures 0.8 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in cords and tubules with large areas of hyalinisation. the individual cells have round hyperchromatic nucleus and moderate cytoplasm. mitosis is discerned.,left breast lump:invasive ductal carcinoma grade 2.modified bloom richardson score 7 9.tubular formation 3nuclear pleomorphism 2mitotic activity 2 7 9
MR1812588,right breast mass. carcinoma breast.,right breast mass biopsy.,received multiple grey white linear core measures 1 2cm. entire tissue processed.,section shows cores of breast parenchyma harboring infiltrating lesion arranged in sheets and nests. the lesional cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. cells exhibit moderate nuclear pleomorphic. mitoses brisk. stroma shows desmoplasia with mixed inflammatory infiltrate.,right breast mass biopsy:invasive ductal carcinoma grade 3.modified bloom richardson score 8 9(3+2+3).
MR1812590,right breast mass carcinoma breast.,biopsy from right breast mass.,received 4 grey white linear cores measures 1 1.5cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets and cords. the lesional cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. cells exhibit moderate nuclear pleomorpism. brisk mitotic activity noted. stroma shows desmoplasia.,biopsy from right mass:invasive carcinoma grade 3modified bloom richardson score 8 9 tubular formation 3nuclear pleomorphism 2mitotic figures 3 8 9
MR1812609,right breast lump carcinoma breast,biopsy from right breast lump,received 4 grey white linear cores measures 0.7 1cm. entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged as clusters and tubules. the neoplastic cells are round to oval have vesicular nuclei cytoplasm. the intervening stroma is elastotic.,biopsy from right breast lump:invasive carcinoma nst grade 2modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1812610,left breast lump carcinoma breast.,left breast lump.,received 3 linear cores grey white measures 0.5 to 1cm. entire tissue processed.,section from the breast parenchyma shows infiltrating neoplasm arranged in sheets and nests. the cells are round to oval hyperchromatic nuclei scant to moderate cytoplasm. admixed lymphocytic infiltrates. atypical mitotic figures are noted.,left breast lump:invasive carcinoma nst grade 3.modified bloom richardson score is (3+2+3) 8 9.
MR1812624,left breast mass.,left breast core biopsy.,received multiple grey white linear cores measures 1 to 2.5cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1812647,left breast mass. carcinoma breast.,left breast lesion biopsy.,received multiple grey white linear cores measures 1 to 2.5cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in nests and few tubules. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphic. mitoses 6 8 10hpf. stroma shows desmoplasia.,left breast lesion biopsy:invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9 (2+2+2).ductal carcinoma in situ solid type noted. (intermediate nuclear grade).
MR1812671,right breast mass. carcinoma breast.,right breast mass biopsy.,received 4 grey white linear cores measures 0.5 to 1.5.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets and nests. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. mitoses 5 6 10hpf. stroma shows desmoplasia. focal necrosis seen.,right breast mass biopsy:invasive carcinoma nst ductal origin grade 2.modified bloom richardson score is 7 9 (3+2+2).focal necrosis seen.
MR1812672,carcinoma breast.,left breast lesion biopsy.,received multiple grey white linear cores measures 0.8 to 1.5cm. entire tissue processed.,section shows multiple cores of breast parenchyma showing irregular dilated ducts lined by stratified round to oval cells occupying entire ducts luminary. the cells have small nuclei mild nuclear pleomorphism moderate cytoplasm. all these ducts are lined by myoepithelial cells abluminally.,left breast lesion biopsy:low grade ductal carcinoma in situ (solid and cribriform type).no invasive component seen in the biopsy submitted.
MR1812678,carcinoma right breast.,a) excised sentinel lymph nodes from right axilla. b) excised lump right breast. c) received superior margin (inked surface away from tumor).,a) excised sentinel lymph nodes from right axilla : received fibrofatty tissue measures 3x2x1cm. largest lymphnode measures1.5x1.2cm. cut surface shows fatty infiltrate. entire tissue processed. b) excised lump right breast : received skin with multiple areola with wide local excision measures 6x4.8x4cm. cut surface shows granular cystic tumor measures 3x2.5x2cm. skin ellipse measures 3.5x3cm. nipple areola is unremarkable. distance from margins :superior margin : 2.7 cm.inferior margin : 1.5cm.medial margin : 2 cm.lateral margin : 0.5 cm.deep margin : 1.8 cm.c) received superior margin (inked surface away from tumor) :received single fibrofatty measures 6x5x1.5cm. cut surface unremarkable.,sections studied shows breast parenchyma harboring a partially encapsulated infiltrating cellular lesion arranged predominantly in nests sheets and vague papillary pattern. the cells are relatively monotonous having moderate amount of cytoplasm hyperchromatic nucleus and coarse chromatin occasional mitotic figures are seen. stroma is desmoplastic with dense lymphomononuclear cell infiltrates. areas of hemorrhage and necrosis are seen.,a) right sentinel lymph node biopsy : isolated two lymphnodes are free of tumor(0 2). b) right breast lump wide local excision :solid papillary carcinoma. grade 1.modified br score is 5 9tubule formation : 3nuclear pleomorphism :1mitotic figures :1 ............ 5 9 .............tumor measures 3cm in greatest dimension. lymphovascular invasion not present. perineural invasion is identified. all margins of resection (superior inferior medial lateral and deep) are free of tumor. pathological stage : pt2n0
MR1812694,left breast mass.,left breast lesion biopsy.,received multiple grey white linear cores measures 1.5 to 2.5cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets nests and few tubules. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. mitoses 10 12 10hpf. stroma shows desmoplasia ductal carcinoma in situ (comedo type)seen.,left breast lesion biopsy:invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9 (2+2+3).ductal carcinoma in situ is seen (comedo type) with intermediate nuclear grade.
MR1812728,left breast mass.,biopsy from left breast mass,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,section show multiple cores of breast parenchyma showing dilated ducts lined by stratified large of round to oval cells having mild atypia occupying entire ducts luminary and lined by myoepithelial cells abuluminary with few ducts are showing epithelial with section mid calcification seen tiny focus of invasive carcinoma seen amidst dense areas of hyalinisation.,biopsy from left breast mass:extensive ductal caricnoma in situ( cribriform and solid type ) lower grade with tiny focus of invasive carcinoma.
MR1812830,carcinoma right breast.,right breast right modified radical mastectomy.,received in : formalinprocedure : modified radical mastectomy.laterality : righttotal dimensions:medial to lateral : 24 cmsuperficial to deep : 6 cmsuperior to inferior : 19 cmskin ellipse : normaltumor : singledistance to nearest separate tumor foci : 2x1.5x1.5 cmlocation of tumor : upper outer quadrant.margins of tumor : ill defineddeep margin : 1 cmmuscle : absentadjacent breast : fibrofatty axillary tail : 5x5x1.5 cm,the sections examined shows breast parenchyma with infiltration by tumor in cords tubules nests and sheets. intervening desmoplastic stroma is seen. focal areas shows micropapillary pattern in the form of nests of tumor cells surrounded by retraction space. tumor cells are cuboidal to polygonal with high n:c ratio enlarged vesicular irregular nuclei with occasional showing prominent nucleoli. perineural invasion is identified. section from nipple and areola is unremarkable (free from malignancy). focal dcis is noted cribriform pattern. one of ten lymph nodes isolated shows tumor deposits (1 10). perinodal spread present. deep margin is free of tumor.,right breast right modified radical mastectomy :infiltrating ductal carcinoma nst grade 2. tumor measures 2.5 cm in the greatest dimension. invasive component 2.5cm. ductal carcinoma in situ measures 2.0cm. modified score is 6 9. tubule formation : 3 nuclear pleomorphism :2 mitotic figures : 1 lymphovascular invasion is identified. perineural invasion is identified. posterior resection margin is free of tumor. nipple areola is free of tumor.lymph nodes : 10 lymph nodes metastases : seen in single lymph node (1 10). perinodal spread is not present.pathological stage : pt2n1asummary : infiltrating ductal carcinoma nst. grade 2.tumor grade : grade 2.lymph nodes : 10 lymph nodes metastases : seen in single lymph node (1 10).perinodal spread is not present.
MR1812861,left breast lump carcinoma breast,biopsy from left breast lump.,received 4 grey white linear cores measures 1.5 2cm. entire tissue processed.,section shows breast parenchyma showing dilated ducts lined by stratified layer of round to oval cell occupying entire ducts luminary with mild atypia. all these ducts are lined by myoepithelial cells abluminally. focal calcification noted.,biopsy from left breast lump:low grade carcinoma in situ( solid type)invasion could not be made out in the section provided.
MR1812866,left breast mass carcinoma breast.,biopsy from left breast mass,received 4 grey white linear cores measures 1.5 2cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring malignant epithelial cells arranged in micropapillary and tubular pattern.the cells have scant eosinophilic cytoplasm. large irregular nucleus and prominent eosinophilic nucleoli stroma shows inflammatory infiltrate and isolated tumor cells.,biopsy from left breast mass:invasive carcinoma ( micropapillary and mucinous features) grade 2modified bloom richardson score is ( 2+2+2)6 9
MR1812879,left breast mass carcinoma breast.,left breast mass biopsy.,received multiple grey white linear cores measures 0.8 to 1.2cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in cords and nests. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. stroma shows desmoplasia. mitotic 5 6 10hpf lymphocytic infiltrate seen.,left breast mass biopsy:invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9 (3+2+2).
MR1812886,known case of carcinoma right breast.,biopsy from right breast.,received 6 grey white linear cores measures 0.5 1.5cm. entire tissue processed.,section reveal linear cores tumor infiltrating breast parenchyma. the tumor is composed of large polygonal to oval cells with high n c ratio hyperchromatic pleomorphic nucleus and moderate eosinophilic cytoplasm arranged as nests and trabecular mitosis are 8 10 10 hpf. intervening stroma shows desmoplasia lymphomononuclear infiltrate.,biopsy from right breast:invasive ductal carcinoma ( grade 3).modified bloom richardson score is 8 9(3+3+2).
MR1812897,lump left breast.,wild local excision of lump left breast,received single skin covered soft tissue measures 8.5x8x6.5cm. skin ellipse measures 8.5x1cm surface of the skin unremarkable. cut surface solid and cystic mass solid area measures 5.5x3.5x3cm. distance from margins : superior margin : 01.cm.inferior margin : 0.1cm.medial margin : 1 cm.lateral margin : 1 cm.deep margin : 0.1 cm.,sections studied show breast parenchyma harboring an infiltrating lesion arranged in sheets. the cells are pleomorphic having abundant amount of pale eosinophilic cytoplasm vesicular nucleus and prominent nucleoli. brisk mitotic activity is noted. stroma is desmoplastic with extensive areas of necrosis. interspersed are lymphomononuclear cell infiltrates. superior inferior and deep margins are close 0.1cm away from tumorhowever all the inked margins are free of tumor,left breast wide local excision :invasive ductal carcinoma grade 3.modified br score is 9 9tubule formation : 3 nuclear pleomorphism : 3mitotic figures : 3 ............ 9 9 .............tumor measures 5.5cm in greatest dimension. lymphovascular invasion and perineural invasion are not seen. all the inked margins are free of tumor
MR1812900,left breast mass. carcinoma breast.,usg guided trucut biopsy of left breast mass.,received 3 grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section studied shows linear cores of breast hyperplastic ductal epithelial cells which are monotonus population with abundant eosinophilic cytoplasm eccentric nucleus coarse chromatin. there is prominent myoepithelial layers around these cells. stroma shows hyalinisation.,usg guided trucut biopsy of left breast mass:ductal carcinoma in situ with suspicious focus of invasion. solid papillary neuro endocrine features.suggest ihc.
MR1812904,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.2 to 0.8cm. entire tissue processed.,section studied from multiple linear biopsy from lesional tissue shows hyperplastic stroma with mild increased stromal cellularity ductal epithelium shows mild hyperplasia cuboidal cells with scant eosinophilic cytoplasm bland nucleus. scant mitotic figures seen.,biopsy from left breast lump:biphasic tumor possibility of benign phylloides tumor is considered.
MR1812914,left breast mass carcinoma breast.,left breast biopsy.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in cords and sheets. the tumor cells have round nucleus dispersed chromatin prominent nucleoli and moderate infiltrate and desmoplasia.,left breast biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1812924,right breast lump carcinoma breast.,biopsy from right breast.,received 3 grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section shows linear cores of breast tissue infiltrated by a neoplasm arranged in nests sheets and cords. the neoplastic cells are round to oval having hyperchromatic nuclei moderate cytoplasm. stroma shows desmoplasia.,biopsy from right breast:invasive carcinoma grade 2.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic activity 2 7 9
MR1812939,right breast mass carcinoma breast,biopsy from right breast.,received 5 grey white linear cores measures 0.5 1.2cm. entire tissue processed,section studied from multiple linear cores of lesional tissue shows maligant breast ductal epithelial cells arranged predominantly in sheets nests and in singles. these cells have scant cytoplasm large irregular overlapping nucleus coarse chromatin and inconspicuous nucleoli plenty of atypical mitosis and necrosis seen.,biopsy from right breast:invasive carcinoma nst.modified bloom richardson score is 8 9(3+2+3).
MR1812940,right breast mass carcinoma breast.,biopsy from right breast mass.,received 4 grey white liner cores measures 1 1.5cm. entire tissue processed.,section shows multiople cores breast parenchyma harboring infiltrating lesion arranged in nests and sheets. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. mitosis 5 6 10 hpf. stroma shows desmoplasia lymphocytic infiltrate seen.,biopsy from right breast mass:invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9(3+2+2).ductal carcinoma in situ ( comedo type) intermediate nuclear grade.
MR1812944,carcinoma left breast.,left modified radical mastectomy post lumpectomy,received in : formalin procedure : modified radical mastectomy laterality : lefttotal dimensions : medial to lateral :18cm superficial to deep : 6cm superior to inferior : 14cmskin ellipse :13x7cmnipple :normal scar surgical defect : absenttumor : single tumor size :2x2x1cmlocation of tumor : central quadrantmargins of tumor : illdefined grey white firm deep margin : 1cmmuscle : absentadjacent breast : fibrofattytissue axillary tail :13x8cmsize of largest node : 2x1x1cm cut surface grey brown hemorrhagic.,section studied shows breast parenchyma with ducts of varying sizes few of which are dilated. stroma shows areas of hyalinisation edema and focal areas of necrosis lymphocytes foamy histiocytes and foreign body giant cells are present.,left modified radical mastectomy post lumpectomytumor bed : no residual tumor present however the lymph node shows metastatic tumor deposits.histological type:no residual tumor focal necrosis areas and granulation tissue surrounding ducts show adenosis and fibrocystic change.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes 20 lymph nodes metastasis 1 (1 20) perinodal spread is present.summary:no residual tumor seen. however lymph node shows metastatic tumor depositslymph node status 1 20 perinodal spread is present.
MR1812948,left breast mass carcinoma breast.,biopsy from left breast.,received 4 grey whit linear cores 0.6 1.5cm. entire tissue processed.,section studied from multiple linear cores of lesional tissue shows malignant ductal epithelial cells in nests. singles and forming vague illdefined ducts. these cells have scant eosinophilic cytoplasm irregular nuclear margin coarse nucleus and prominent eosinophilic nucleolus. plenty of atypical mitosis seen. stroma show dense desmoplasia.,biopsy from left breast:invasive carcinoma nstmodified bloom richardson score is 6 9(2+2+2).
MR1812955,left breast mass. carcinoma breast.,left breast lesion.,received multiple grey white linear cores measures 1 to 1.5 cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in sheets. the cells have round hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm.,left breast lesion biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1812967,carcinoma right breast.,biopsy from multiple skin nodule over breast.,received 2 grey white soft tissue bits measures 1.5x1x0.5cm. entire tissue processed.,section studied shows stratified squamous epithelium with focal ulceration. subepithelium shows sheets of malignant epithelial cells forming vague. illdefined lobules composed of cells with scant eosinophilic cytoplasm irregular nuclear margin vesicular chromatin prominent nucleoli. abundant mitotic figures are seen. dense lymphoplasmnacytic infiltrate present. these focus of pagetoid spread into epithelium.,biopsy from multiple skin nodule over breast:invasive carcinoma nst .modified bloom richardson score is 9 9.tubular formation 3.nuclear pleomorphism 3mitotic activity 3 9 9
MR1812973,right breast mass carcinoma breast,biopsy from right breast mass,received 3 grey white linear cores measures 1.5 2cm. entire tissue processed.,section show linear cores of tissue showing infiltration by tumor is arranged in sheets cores and shows areas of micropapillary pattern in the form of nest of cells showing peripheral palisading and . surrounded clear retration space. focally tubular are seen. tumor cells are cuboidal to polygonal with increased n:c ratio enlarged round to oval nuclei occasional prominent nucleoli and moderate cytoplasm.,biopsy from right breast mass:invasive carcinoma with focal micropapillary pattern grade 2modified bloom richardson score 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR1813066,case of carcinoma left breast,a) revised medial margin.b) left breast lump wide excision ( post lumpectomy nact).c) left axillary dissection.,a) received fibrofatty tissue measures 7x9x3cm.one surface shows (suture away from tumor).cut surface fibrosis.b) received skin covered fibrofatty tissue measures 8x7.5x4cm.skin ellipse measures 5x4.5xcm. a part of nipple areola measures 2.5x0.5cmcut surface shows grey white tumor measures 1.8x1.2x1cmdistance from margins:superior margin : 2.5cminferior margin : 4cmmedial margin :4.5cmlateral margin : 2.5cmdeep margin :2cmrepresentative sections are submitted.c) received fibrofatty tissue measures 10x6x3cm.largest lymph node measures 2x1x1cm cut surface unremarkable,section shows no residual tumor. section shows breast parenchyma with a lesion having intralobular stroma enclosing glandular spaces. the stroma has benign looking spindle cells and gland are lined by low cuboidal epithelium. no atypia malignancy cells seen.,b) left breast lump wide excision ( post lumpectomy nact):no residual tumor is seen. adjacent breast shows features consistent with fibroadenoma. all margins of resection are free of tumor.a) revised medial margin: free of tumor.c) left axillary dissection: sixteen lymph nodes are identified are free of tumor( 0 16).pathological stage : ypt0n0
MR1813081,left breast lump possibility of carcinoma breast.,left breast lump biopsy.,received multiple grey white linear cores measures 0.5 1.5cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue harboring an invasive neoplasm arranged in nests vague acinar pattern and trabecular lesional cells show increased n c ratio moderate eosinophilic cytoplasm pleomorphic hyperchromatic nucleus few showing prominent nucleoli . stroma is desmoplastic with mild inflammatory infiltrates. mitotic activity discerned,left breast lump biopsy:invasive carcinoma no special type nos grade iimodified bloom richardson score is 3+2+2 7 9
MR1813082,right breast lump carcinoma breast.,biopsy from right breast lump,received 4 grey white linear cores measures 1 2cm. entire tissue processed.,section studied from multiple linear cores shows malignant ductal epithelial cells in predominantly in sheets small nests and individual cells. plenty of mitosis seen. stroma shows desmoplasia with lymphoplasmacytic infiltrate. necrosis seen.,biopsy from right breast lump:invasive carcinoma no special type grade iimodified bloom richardson score is 7 9(2+3+2).
MR1813084,left breast lump carcinoma breast.,biopsy from left breast lump.,received 8 grey white linear cores measures 0.5 0.2cm. entire tissue processed.,section shows linear cores of tissue showing infiltrating tumor in nests and cords. focal cribriform spaces are seen. the tumor cells are pleomorphic cuboidal to polypoidal with increased n c ratio hyperchromatic pleomorphic nuclei with moderate cytoplasm. areas of necrosis are seen.,biopsy from left breast lump:invasive carcinoma nst grade 2modified bloom richardson score is 7 9tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1813099,right breast neoplastic.,biopsy from right breast lesion.,received 6 grey white linear cores measures 0.8 1cm. entire tissue processed.,section studied from the multiple linear cores of lesional tissue shows malignant ductal epithelial cells forming vague illdefined tubules and cords. the cells have scant eosinophilic cytoplasm irregular nucleus coarse chromatin inconspicuous nucleoli. stroma shows lymphoplasmacytic infiltrate.,biopsy from right breast lesion:invasive carcinoma no special type grade 2modified bloom richardson score is 7 9( 2+3+2).
MR1813103,left breast mass. carcinoma breast.,left breast mass biopsy.,received multiple grey white linear cores measures 1 to 2cm. entire tissue processed.,section shows multiple cores of breast parenchyma with extensive hyalinization. few foci show atypical cells having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism.,left breast mass biopsy:small focus of atypical cells clusters seen highly suspicious of invasive carcinoma.note:a repeat biopsy is suggested for ihc as tumor volume is very scant.
MR1813164,right breast mass carcinoma breast.,biopsy from right breast,received multiple grey white linear cores measures 1.5 2cm. entire tissue processed.,section reveal linear core of breast parenchyma with multiple foci ducts distended with atypical cells showing high n c ratio moderately pleomorphic vesicular nucleus conspicuous nucleoli and moderate clear to eosinophilic cytoplasm. few of these ducts show central necrosis. the tumor cells are seen also seen infiltrating as nests and cords in a desmoplastic stroma mitosis are 7 10hpf. stroma shows lymphomononuclear infiltrate.,biopsy from right breast:invasive carcinoma( nst) with ductal carcinoma in situ grade2.modified bloom richardson score is 7 9(3+2+2).
MR1813201,left breast lesion carcinoma breast.,biopsy from left breast.,received multiple grey white linear cores measures 2 to 2.5cm. entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged in cords and clusters. the neoplastic cells have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is fibrosis.,biopsy from left breast:invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic activity 2. 7 9.
MR1813234,left breast lump carcinoma breast.,left breast core biopsy.,received multiple grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1813239,right breast lump carcinoma breast.,biopsy from right breast lump.,received grey brown multiple soft tissue bits measures 0.2x0.1x0.1cm. entire tissue processed.,section shows scant tissue with predominantly hemorrhage and occasional fragments of tumor. the tumor is arranged in sheets and cords with round to polygonal cells showing increased n:c ratio hyperchromatic mildly pleomorphic ovoid nuclei and moderate cytoplasm. fragments of fibrous tissue are also seen.,biopsy from right breast lump:scanty tissue.dysplastic ductal cells are seen in clusters.highly suspicious of invasive carcinoma.suggest repeat biopsy.
MR1813258,carcinoma right breast.,a) blue + hot nodes.b) hot nodes. c) right modified radical mastectomy.,a) blue + hot nodes. received 3 lymph nodes 1 largest measures 1.5x1x1cm. cutsurface fatty infiltration. entire tissue processed. b) hot nodes. received 2 lymph nodes. largest measures 2.5x1x1cm. cutsurface fatty infiltration. entire tissue processed. c) right modified radical mastectomy. received in : formalin. procedure : right modified radical mastectomy. laterality : right. total dimensions : medial to lateral : 20 cm. superficial to deep : 5 cm. superior to inferior : 19 cm.skin ellipse : 18x9cm.nipple : normal. scar surgical defect : not seen. tumor size : 4x3.5x2.5cm. location of tumor : upper inner quadrant. margins of tumor : ill identified. deep margin : 1.5 cm.muscle : absent. adjacent breast : fibrofatty tissue. axillary tail : 4x4x3cm. size of largest node : 1.2x1x1cm. cutsurface unremarkable. microscopy:c) sections studied show breast parenchyma harboring lesion arranged in nests and tubules. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma is desmoplastic with areas of hemorrhage and necrosis.,a) right sentinel lymph node biopsy. two of three isolated lymphnodes show metastatic tumor deposits on frozen section. (2 3). however in deeper paraffin sections the tumor tissue is depleted. b) right sentinel lymphnode biopsy hot nodes. isolated two lymph nodes show granulomatous inflammation. (0 2).c) right modified radical mastectomy :histological type : invasive ductal carcinoma. grade ii. tumor measures maximum dimension 4 cm.invasive component measures 4 cm.modified br score is 6 9tubule formation : 2 nuclear pleomorphism : 2mitotic figures : 2 ............ 6 9 .............ductal carcinoma in situ not seen. lymphovascular invasion identified. perineural invasion is not seen.posterior resection margin is free from tumor. nipple and areola is unremarkable.mrm,lymphnodes : 9 lymph nodes metastasis : 2 (2 9) perinodal spread seen. (frozen section 2 nodes positive out of 5 nodes.paraffin routine section: 2 nodes positive out of 9 nodes.total. no. nodes : 4 out of 14 nodes)summary : invasive carcinoma right breast. tumor grade: ii.lymph node status: 4 14 perinodal nodal spread seen.
MR1813286,carcinoma left breast post lumpectomy.,a) left breast left beast conservative surgery(post lumpectomy).b) re excised lateral margin. c) left breast axillary clearance.,a) breast conservative surgery.received wide local excision measures 8x8x5cm. skin 6.5x1cm. ill defined fibrous area measures 7x 6 x 4 cm. no definite tumor seen. distance from margins : superior margin : 0.4 cminferior margin : 0.6 cmmedial margin : 0.5 cmlateral margin : 0.5 cmdeep margin : 0.6 cmb) re excised lateral margin : received fibrofatty tissue measures 3.5x2.5x1.5cm. inked surface identified. c) left breast axillary clearance. received fibrofatty tissue measures 6x4x3cm. largest lymph node 0.8x0.7x0.6cm. cut surface grey white.,sections show no residual tumor cells. breast parenchyma with fibrosis adenosis cystic change lymphomononuclear inflammatory infiltrates collections is seen. all the margins of resection are free of tumor.,a) left breast left beast conservative surgery(post lumpectomy) :no residual tumor is seen. treatment related changes are seen. all the margins are free of tumor. b) revised lateral margin : free of tumor. c) left axillary clearance : thirteen lymph nodes are identified negative for malignancy(0 13).
MR1813316,carcinoma right breast,a) blue node hotb) right sentinel lymph node.c) right mastectomy specimen,a) received single fibrofatty tissue measures 1.7x0.8x0.5cmisolated measures 0.3x0.2x0.2cmb) received single fibrofatty tissue measures 0.8x0.5x0.3cmreceived in : formalinprocedure : right modified radical mastectomy laterality : right total dimensions : medial to lateral :15cm superficial to deep :5cm superior to inferior:10cmskin ellipse : 13x5.5cm nipple : normal scar surgical defect :not see4ntumor : no tumor identified grossly lumpectomy bed measuring 2.5x2x1cm. deep margin : 0.3cmadjacent breast : fibrofatty tissue with dense fibrosismuscle : absent,section studied show breast parenchyma with focal proliferating ductules of varying sizes lined by inner epithelial cells and an outer intact myoepithelial layer.stroma shows areas of hyalinisation edema and elastosis. interspersed are scattered lymphomononuclear cell infiltrate.,a) right sentinel lymph node blue +hot node:isolated single lymph node is free of tumor(0 1)b) right sentinel lymph node suspicious nodes:isolated single lymph node is free of tumor (0 1)c)right mastectomy post lumpectomy:histological type : no residual tumor seen.ductal carcinoma in situ is not seenlymphovascular invasion is not seen.perineural invasion is not seenposterior resection margin is free of tumornipple and areola is unremarkable summary: no residual tumor seen right breast.lymph node status : 0 2( blue +hot node 0 1 suspicious node (0 1).
MR1813326,left breast lump carcinoma breast.,left breast core biopsy.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. areas of necrosis are seen.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1813334,carcinoma breast.,right breast mass core biopsy.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cored of breast tissue infiltrated by tumor cells in nests and sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast mass core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1813360,carcinoma right breast.,a) right modified radical mastectomy post nact.b) revised deep margin of pectoralis major muscle.,a) received in : 10 nbf.procedure : right modified radical mastectomy post nact.laterality : right.total dimensions : medial to lateral 19cm. superficial to deep 3.5cm. superior to inferior 14cm.skin ellipse : 13x9cm.nipple : normal scar surgical defect : absent.tumor : single.tumour size : 2.5x1.2x1cm. location of tumor : 9 o clock illdefined grey white to yellowish a cyst measures 1.5x1x1cm seen adjacent to tumor distance between tumor a cyst is 0.5cm.deep margin : 1cm.adjacent breast : 10x8x4cm. size of largest node : 2.5x1.5x1cm.b) received fibrofatty tissue measures 5x3.5x0.6cm.,sections show breast parenchyma with extensive areas of ductal carcinoma in situ (solid cribriform comedo papillary) of low nuclear grade. a tiny focus of invasive component seen measures 0.3cm in greatest dimension. rest of the areas show fibrosis cholesterol and clefts lymphomononuclear infiltrates.adjacent breast parenchyma shows fibrocystic change.,a) right modified radical mastectomy post nact.histological type:extensive ductal carcinoma in situ (solid cribriform comedo papillary) with foci of residual invasive carcinoma.tumor measures maximum dimension 2.5cminvasive component measures 0.3cmductal carcinoma in situ measures 2.2cmductal carcinoma in situ is present.lymphovascular invasion is absent.perineural invasion is absent.posterior resection margin is free of tumor.nipple and areola is free of tumor.lymph nodes: 10 lymph nodes metastasis: 0 (0 10).b) revised deep margin of pectoralis major muscle:free of tumor.summary:right modified radical mastectomy post nact.extensive ductal carcinoma in situ with foci of residual invasive carcinoma.lymphnode status: 0 10.
MR1813400,left breast mass carcinoma breast.,biopsy from left breast mass,received 4 grey white linear cores measures 1 1.5cm. entire tissue processed.,section shows linear trucut cores comprising nests and sheets of atypical with moderately pleomorphic hyperchromatic nuclei and eosinophilic cytoplasm. mitotic figures discerned. small focus of necrosis seen. stroma is desmoplastic.,biopsy from left breast mass:invasive carcinoma no special type grade 2.modified bloom richardson score is 3+2+2 7 9.
MR1813417,right breast lump birads iv,biopsy from right breast lump,received 5 grey white linear cores measures 2 2.5cm. entire tissue processed.,section shows linear trucut cores comprising of sheets clusters and singly scattered highly pleomorphic cells with hyperchromatic nucleus dispersed in a desmoplastic stroma showing moderate mononuclear inflammatory infiltrate.,biopsy from right breast lump:invasive carcinoma no special type grade 3modified bloom richardson score is 3+3+2 8 9
MR1813430,left breast mass carcinoma breast.,left breast mass biopsy.,received 4 grey white linear cores measures 1 2cm. entire tissue processed.,section shows tumor cells in sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1813435,right breast mass.,biopsy from right breast mass.,received 5 grey white linear core measures 0.5 to 1cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as solid nests. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. areas of necrosis seen.,biopsy from right breast mass. :invasive carcinoma nst. grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1813466,right breast mass carcinoma breast.,biopsy from right breast mass.,received 3 grey white linear cores measures 2 2.5cm. entire tissue processed.,section shows infiltrating neoplasm arranged in sheet and nests. the cells are round to oval hyperchromatic nuclei abundant cytoplasm. adjacent stroma shows desmoplasia. atypical mitotic figures and necrosis.,biopsy from right breast mass:infiltrating ductal carcinoma grade 2.modified bloom richardson score is 7 9(3+2+2).areas of necrosis seen.
MR1813493,left breast retroareolar lesion carcinoma breast.,biopsy form left breast.,received 3 grey white linear cores measures 1 to 2cm. entire tissue processed.,section shows infiltrating neoplasm arranged in sheets and nests. the cells are round to oval hyperchromatic nuclei abundant eosinophilic cytoplasm. adjacent stroma shows lymphocytic infiltrates. atypical mitotic figures are seen. mitosis 4 5 10hpf.,biopsy form left breast:invasive ductal carcinoma grade 2.modified bloom richardson score is (3+2+2)7 9.
MR1813502,right breast carcinoma.,a) right breast wide local excision. b) right axillary clearance.,a) right breast wide local excision : received wide local excision of breast measures 8x5x4cm. skin ellipse 3x1cm. cut section shows tumor measures 1.8x1.1x1cm. distance from margins : superior margin : 2 cm.inferior margin : 1 cm.medial margin : 1 cm.lateral margin : 3 cm.deep margin : 2 cmb) right axillary clearance : received fibrofatty tissue measures 10x6x5cm. largest measures 2x2x1cm. cutsurface grey brown.,a) section studied show breast parenchyma harboring an infiltrating lesion arranged in sheets and nests. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma is desmoplastic with areas of hemorrhage and necrosis.,a) right breast wide local excision : invasive ductal carcinoma grade 3.modified br score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 ............ 6 9 .............tumor measures maximum dimension 1.8cm.invasive component measures 1.0 cm.ductal carcinoma in situ measures 0.8cm.ductal carcinoma in situ solid cribriform and comedonecrosis pattern noted. lymphovascular invasion perineural invasion are not seen.all margins of resection (superior inferior medial and lateral) are free of tumor.b) right axillary clearance : isolated all six lymphnodes are free of tumor(0 6). pathological stage : ypt1n0.
MR1813503,left breast mass carcinoma breast,biopsy from left breast mass.,received 4 grey white linear cores measures 1 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma with infiltrating neoplasm arranged in sheets nests. the cells are round to oval hyperchromatic nuclei scant to moderate cytoplasm. adjacent stroma shows lymphoplasmacytic infiltrates. few atypical mitotic figures noted.,biopsy from left breast mass.invasive carcinoma nst grade 2.modified bloom richardson score is (3+2+2) 7 9.
MR1813539,right breast lump carcinoma breast.,biopsy from right breast lump.,received multiple grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section shows multiple fragments of breast parenchyma with a lesion arranged in nests and sheets. the cells are round to oval hyperchromatic nuclei abundant eosinophilic cytoplasm. extensive areas of necrosis is noted. atypical and brisk mitotic figures are noted. ductal carcinoma in situ component with comedonecrosis is noted. adjacent stroma shows desmoplasia.,biopsy from right breast lump:invasive ductal carcinoma with ducal carcinoma in situ comedonecrosis grade 2modified bloom richardson score is (3+2+2)7 9.ductal carcinoma in situ noted.
MR1813552,right breast lump. carcinoma breast.,right breast lump.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows infiltrating neoplasm arranged in sheets and nests. the cells are large hyperchromatic nuclei abundant eosinophilic cytoplasm. adjacent dense lymphoplasmacytic infiltrates. admixed desmoplastic stroma. atypical mitotic figures noted. mitotic figures 4 5 10hpf. areas of necrosis noted.,right breast lump:invasive ductal carcinoma grade 3.modified bloom richardson score is (3+3+2)8 9.
MR1813573,case of right breast lump.,biopsy from right breast lump.,received 4 grey white linear cores measures 1.5 2cm. entire tissue processed.,section show multiple cores of breast parenchyma harboring infiltrating lesion arranged in nests cords tubules. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. mitosis 5 6 10 hpf. stroma shows hyalinisation lymphocytic infiltrate.,biopsy from right breast lump:invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9.tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9
MR1813604,right breast lump carcinoma breast.,right breast core biopsy.,received multiple grey white linear cores measures 1 to 2cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1813606,carcinoma left breast,a) blue + hot nodes.b) hot nodesc) left mastectomy.,a) hot +blue nodes isolated 4 lymph nodes largest measures 1x0.8x0.7cm.b) received hot nodes isolated 1 lymph nodes measures 0.3x0.2x0.1cm.c) received in : formalin procedure : l mastectomy laterality : lefttotal dimensions : medial to lateral :17cm superficial to deep :3.8cm superior to inferior : 14cmskin ellipse :13.5x10cmnipple :normal scar surgical defect : not identifiedtumor : single tumor size : 3.5x3x3.2cm location of tumor : upper outer quadrantmargins of tumor : iildefined deep margin : 1cmmuscle : 3x2cmadjacent breast : fibrofatty tissue axillary tail : not submitted.size of largest node :1x1x0.5cm,c) section from tumor show cells arranged in tubules nests and sheets cells have moderate amount of pale eosinophilic cytoplasm pleomorphic round to oval vesicular nuclei with prominent nucleoli mitotic figures discerned. surrounding stroma shows desmoplasia with lymphomononuclear infiltratessection from deep with muscle are free of tumorsection from nipple and area are free of tumor.,left mastectomy:histological type: invasive ductal carcinoma nactgrade :1tumor component maximum dimension 3.5cm.invasive component measures 3cm.modified bloom richardson score is 6 9.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2ductal carcinoma in situ area of necrosis seenlymphovascular invasion presentperineural invasion presentposterior resection margin is free of tumor.nipple and areola is free of tumorlymph nodes 8 lymph nodes no metastasis (0 8).left sentinel lymph node : 6 lymph nodes isolated no metastases (0 6).pathological stage pt2n0mxsummary:invasive ductal carcinoma left breasttumor grade moderately differentiated lymph nodes status 0 8 lymph nodes isolated no metastasisleft sentinel lymph nodes (0 6) isolated no metastasis
MR1813617,left breast lump neoplastic.,left breast lump biopsy.,received 5 grey white linear cores measures 1 2cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in sheets and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1813713,left breast lesion neoplastic.,biopsy from left breast.,received multiple grey white linear cores measures 1cm. entire tissue processed.,linear cores of breast parenchyma harboring a neoplasm arranged as clusters cords and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclear and moderate cytoplasm. areas of necrosis seen.,biopsy from left breast:invasive carcinoma nst grade 2.modified bloom richardson score is 6 9.tubular formation 3nuclear pleomorphism 2mitotic activity 1 6 9
MR1813753,right breast lump carcinoma breast.,biopsy from right breast.,received multiple grey white linear cores measures 1.2 to 1.5cm. entire tissue processed.,section studied show fibrocollagenous tissue harboring lesion arranged in tubular solid sheets nested cords pattern. lesional cells are round to oval having hyperchromatic nuclei moderate eosinophilic cytopalsm. few mitotic figures also discerned. adjacent stroma shows pools of mucin and desmoplastic change.,biopsy from right breast:invasive carcinoma nst with mucinous differentiation (grade 1).modified bloom richardson score is 4 9.tubular formation 2nuclear pleomorphism 1mitotic activity 1 4 9
MR1813759,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 1 2cm. entire tissue processed.,section reveal linear core biopsies of infiltrative tumor composed of round to polygonal cells arranged in nests and trabecular pattern. the cells show high n c ratio and hyperchromatic nucleus with moderate pleomorphism .mitosis are 3 4 10 hpf. intervening stroma shows desmoplasia.,biopsy from right breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9(3+1+2).
MR1813773,right breast lump carcinoma,right breast lump.,received in : formalin procedure : modified radical mastectomy laterality : righttotal dimensions : medial to lateral :18cm superficial to deep : 4.8cm superior to inferior : 14.5cmskin ellipse :15x12cmnipple :normal scar surgical defect : not seentumor : single tumor size : 2.8x2.3x1.8 overlying skin is retracted location of tumor : upper outer quadrant.margins of tumor : iil defined deep margin : 1.8cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail : 8x6x4cmsize of largest node :3.5x3x2.5xcm. cut surface mucinous,multiple section show clumps and groups of cells with areas calcification having pleomorphic nucleus and scanty cytoplasm surrounded with pools of mucin ( mucinous carcinoma). in focal areas of clumps of solid cells are seen with pleomorphic nucleus with hyperchromatic nucleus ( focal areas of invasive ductal carcinoma ),right modified radical mastectomy:histological type: mucinous carcinoma with focal areas of invasive ductal carcinoma.grade :2tumor component maximum dimension 2.8cm.invasive component measures2.8cm.ductal carcinoma in situ measures not identified.modified bloom richardson score is 7 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2lymphovascular invasion presentperineural invasion not identifiedposterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes 15 lymph nodes metastasis 3 nodes show metastatic deposit of tumor out of 15 nodespathological stage: pt2n1.summary:mucinous carcinoma with focal areas of invasive ductal carcinomagrade :2lymph nodes3 nodes show metastatic deposit of tumor out of 15 nodesperinodal spread present.
MR1813802,well defined lobulated hypoechoic lesion in right breast birads iv,biopsy from right breast lump near nipple.,received 4 grey white linear cores measures 1 1.5cm. entire tissue processed.,linear cores of breast tissue infiltrating by a neoplasm arranged as nests and islands. the neoplastic cells exhibit moderate nuclear plemorphism have vesicular nuclei and moderate cytoplasm. the intervening stroma is scant.,biopsy from right breast lump near nipple:invasive carcinoma grade 2modified bloom richardson score is 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1813840,left breast lump carcinoma breast.,biopsy from left breast.,received multiple grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section studied show fibrocollagenous tissue harboring lesion arranged nest cord pattern. lesional cells have round to polygonal having hyperchromatic nuclei moderate eosinophilic cytoplasm. mitotic figures also discerned. adjacent stroma show desmopalstic change. ductal carcinoma in situ with comedo necrosis seen.,biopsy from left breast:invasive ductal cell carcinoma (grade 2).modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic activity 2 7 9 ducal carcinoma in situ with comedonecrosis seen.
MR1813844,right breast solid cystic lesion birads v.,biopsy from right breast lump.,received 3 linear cores grey white grey brown cores measures 0.8 1.2cm. entire tissue processed.,linear cores of breast parenchyma harboring a neoplasm arranged as clusters and islands floating in lakes of mucin. the neoplastic cells have hyperchromatic nuclei and scant cytoplasm.,biopsy from right breast lump:invasive carcinoma with mucinous areas grade 1modified bloom richardson score is 5 9tubule formation 3nuclear pleomorphism 1mitotic figures 1 5 9
MR1813852,left breast lump.,biopsy from left breast.,received 3 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied show fibrocollagenous tissue harboring lesion arranged in tubular nest cord pattern. lesional cells are round to oval having hyperchromatic nuclei moderate eosinophilic cytopalsm. mitotic figures also discerned. adjacent stroma show desmopalstic change.,biopsy from left breast:invasive ductal cell carcinoma grade 1.modified bloom richardson score is 5 9.tubular formation 2nuclear pleomorphism 2mitotic activity 1 5 9
MR1813856,complaints of left breast lump carcinoma breast.,biopsy from left breast lump.,received 6 grey white linear cores measures 1 2cm. entire tissue processed.,section studied show fibrocollagenous tissue harboring lesion arranged in tubular nested pattern and few focal cribriform pattern also seen. lesional cells are round to polygonal having hyperchromatic nuclei moderate eosinophilic cytoplasm. mitotic figures also discerned. adjacent stroma show desmoplastic change . perineural invasion not seen.,biopsy from left breast lump:invasive carcinoma with lobular features grade 1modified bloom richardson score is 5 9 (2+2+1)
MR1813873,right breast birads with lesion.,biopsy from right breast.,received multiple grey white linear cores measures 0.5 to 1.5cm. entire tissue processed.,sections studied from lesional tissue harbor an invasive neoplasm composed of cells arranged in sheets. the cells have scant eosinophilic to clear cytoplasm irregular hyperchromatic nuclei and coarse chromatin. numerous atypical mitosis seen. stroma shows desmoplastic reaction and lymphomononuclear infiltrate.,biopsy from right breast:invasive carcinoma of ductal origin nst breast grade iii.tubular formation 3 nuclear pleomorphism 3mitotic activity 2 8 9
MR1813912,carcinoma left breast,a) left breast conservative surgery. post lumpectomyb) left sentinel lymph node blue + hot nodec) left sentinel lymph node hot node.,a) received wide local excision of left breast measures 15x11x5cmskin ellipse measures 9.5x5.5cmsurface shows surgical scar measures 1.5cm in lengthtwo nodules over surface of skin larger nodule measures 0.6x0.5x0.2cmon cut opening cystic lesion drained hemorrhage greenish fluid measures 4x1.5x1.5cmdistance from margins:superior margin 3cminferior margin 3cmmedial margin 4cmlateral margin 2cmdeep margin 2cmb) received fibrofatty tissue measures 6x3.5x1cm identified 3 lymph nodeslargest measures 1.8x1x1cm cut surface fatty infiltrate.c) received fibrofatty tissue measures 3x2.5x1.5cm identified 1 lymph nodes measures 2x1x0.5cm cut surface fatty infiltration.,a) section studied shows breast parenchyma with extensive areas of fibrosis and hyalinisation. there is extensive areas of fat necrosis. lymphomononuclear.aggregates transforming histiocytes hemosiderin alden macrophages and giant cells. areas of hemorrhage and necrosis is seen. no evidence of atypical malignancy seen in the material submitted.,a) left breast conservative surgery. post lumpectomy:no residual tumor is seen.ductal carcinoma in situ is not seenlymphovascular invasion and perineural invasion not seen.all margins of resection ( superior inferior medial lateral and deep) are free of tumor.overlying skin is unremarkable.b) left sentinel lymph node blue + hot node:isolated three lymph nodes are free of tumor (0 3)c) left sentinel lymph node hot node:isolated single lymph nodes is free of tumor (0 1).
MR1813922,right breast lump carcinoma breast.,biopsy from right breast lump.,received multiple grey white linear cores measures 0.6 to 1cm. entire tissue processed.,sections studied from multiple linear cores harbor an invasive neoplasm composed of tumor cells arranged in tubules and nests. the tubules are lined cuboidal epithelium. scant eosinophilic cytoplasm irregular round hyperchromatic nuclei. stroma shows lymphoplasmacytic infiltrates and desmoplasia.,biopsy from right breast lump.invasive carcinoma grade i.modified bloom richardson score is 2+1+1(4 9).
MR1813925,left breast lump neoplastic.,left breast core biopsy.,received multiple grey white linear cores measures 0.8 to 1.5cm. entire tissue processed.,the section shows linear cores of breast parenchyma showing infiltration by tumor cells in nests and focally in tubules. the tumor cells are round to polygonal with round to ovoid hyperchromatic pleomorphic nuclei and moderate cytoplasm. occasional prominent nucleoli are seen. intervening stroma is desmoplastic.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1813948,left breast lump carcinoma breast.,core biopsy left breast lump.,received 3 linear cores measures 0.8 to 1.3cm. entire tissue processed.,the sections show linear cores of breast parenchyma showing infiltration by tumor cells in cords and nests focal tubular and cribriform pattern. the tumor cells are round to cuboidal with increased n:c ratio hyperchromatic nuclei show prominent nucleoli. intervening stroma is desmoplastic.,core biopsy left breast lump:features are suggestive of invasive ductal carcinoma grade 2.modified bloom richardson score 7 9.tubular formation 3nuclear pleomorphism 2mitotic activity 2 7 9
MR1814076,right breast mass highly suggestive of malignancy birads 5,biopsy from right beast lump.,received 4 grey white soft tissue bits measures 0.8 1cm. entire tissue processed.,section studied show linear cores of fibrocollagenous tissue harboring an invasive neoplasm arranged in glandular pattern trabecular cords and solid nests. lesional cells are round to polygonal with increased n c ratio ratio moderate eosinophilic cytoplasm round hyperchromatic nucleus and prominent nucleoli moderate nuclear pleomorphism is seen. mitotic figures are seen occasionally. areas of necrosis seen.,biopsy from right beast lump:invasive ductal carcinoma nst grade ii.modified bloom richardson score is 3+1+2 6 9.
MR1814123,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4grey white linear cores measures 0.5 1cm. entire tissue processed.,section studied shows fibrous tissue harboring an infiltrating lesion arranged in sheets and nests. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma is desmoplastic with dense lymphomononuclear cell infiltrate.,biopsy from left breast lump:invasive carcinoma nst grade 3.modified bloom richardson score is 8 9(3+2+3).
MR1814149,right breast.,biopsy from sternal nodule mammary fold lesion right breast.,received multiple fragmented linear cores measures 0.3 to 0.6cm. entire tissue processed.,section studied shows linear cores of fibroadipose tissue with infiltrating neoplasm arranged in glandular pattern tubules and nests lesional cells are round to polygonal with moderate eosinophilic cytoplasm hyperchromatic nucleus and prominent nucleoli. intranuclear inclusions are seen in few. mitotic figures are 4 6 10hpf. stroma is desmoplastic with myxoid areas. area of necrosis and hemorrhage seen.,biopsy from sternal nodule mammary fold lesion right breast:invasive carcinoma probably ductal origin primary metastatic breast.
MR1814164,prostetomegaly carcinoma breast.,core biopsy prostate.,received multiple grey white linear cores measures 1.2 to 1.7cm. entire tissue processed.,the sections shows linear cores showing benign prostatic tissue. no evidence of malignancy is seen.,core biopsy prostate:benign prostatic tissue.
MR1814180,left breast lump carcinoma breast.,biopsy from left breast lump.,received 3 grey white linear cores measures 1.2 to 1.5cm. entire tissue processed.,section show linear cores of tumor composed of large polygonal cells with high n:c ratio hyperchromatic nucleus and moderate eosinophilic cytoplasm arranged in nests. these cells show moderate pleomorphism and mitosis 1 2 hpf. stroma desmoplasia and lymphomononuclear infiltrate with focal of foreign body giant cells collection.,biopsy from left breast lump:invasive ductal carcinoma nst grade 3.modified bloom richardson score is 8 9.tubular formation 3nuclear pleomorphism 2mitotic activity 3 8 9
MR1814227,carcinoma left breast.,wide excision left breast lump.,received in : 10 nbf.procedure : wide local excisiontotal dimensions : medial to lateral 10cm superficial to deep 6cm superior to inferior 4.5cm.skin ellipse : 8x4cm. nipple : normal scar surgical defect : absent.tumor : single.tumour size : 4.5x4.5x4cm. illdefined grey white with areas of haemorrhage and necrosis. deep margin : 0.2cm.muscle : present.adjacent breast : absent. axillary tail : absent.,section studied show breast parenchyma harboring infiltrative neoplasm arranged in nests cord trabecular pattern. lesional cells are polygonal with large pleomorphic round to oval vesicular nuclei prominent nucleoli moderate amount of clear to eosinophilic cytoplasm. stroma shows dense lymphomononuclear infiltrate. area of hemorrhage and necrosis and hyalinization also seen.,wide excision left breast lump:histological type: invasive carcinoma (nst).grade: iitumor measures maximum dimension 4.5cminvasive component measures 4.2cmductal carcinoma in situ measures 0.3cmmodified br score is 7 9tubule formation: 3nuclear pleomorphism: 2mitotic figures: 2ductal carcinoma in situ is present.lymphovascular invasion is not seen.perineural invasion is not seen.posterior resection margin is 0.1cm away from tumor.elliptical skin soft tissue excised margin are free of tumor.
MR1814260,case of left breast carcinoma,a) left breast wide excisionb) left sentinel node hot nodec) left sentinel node blue hot noded) left sentinel node non blue non hot node.,a) received lumpectomy specimen measures 4x3.5x1.5cmskin ellipse measures 4x0.8cm. cut surface shows tumor measures 1.5x1.4x1.3cmdistance from margin:superior margin : 2cminferior margin : 0.2cmmedial margin : 1cmlateral margin : 2cmdeep margin 0.6cmb) received one lymph node measures 1x0.8x0.6cm. cut surface grey brown.c) received 1 lymph node measures 0.8x0.6x0.4cmcut surface grey brown blue dye noted.d) received 1 lymph node measures 0.5x0.3x0.3cm.,a) section studied shows breast parenchyma with an infiltrating lesion arranged in sheets and nests. the cells are ovoid having moderate amount of pale eosinophilic cytoplasm with peripherally pushed hyperchromatic nucelus ( signet ring cell morphology) mitotic figures are discerned stroma is desmoplastic with occasional scattered lymphomononuclear cell infiltrate. no extracellular mucin is present.,a)left breast conservative surgery:histological type: carcinoma with signet ring cell differentiation.grade :3tumor component maximum dimension 1.5cm.invasive component measures 1.5cm.modified bloom richardson score is 8 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3lymphovascular invasion not seen.perineural invasion not seen.posterior resection margin is free of tumornipple and areola is unremarkable.all inked margins ( superior inferior medial lateral and deep ) are free of tumor.b) left sentinel node hot node:isolated single lymph is free of tumor (0 1)c) left sentinel node blue hot node:isolated four lymph nodes are free of tumor (0 4)d) left sentinel node non blue non hot node:isolated single lymph node is free of tumor (0 1)pathological stage pt2n0summary:carcinoma with signet ring cell differentiation.tumor grade 3lymph nodes status 0 6.note:primary breast composed predominantly or exclusively of signet sing cells are rareadvised ihc er pr her2 ki67 gcdfp 15 cd2 ck7 e cadherin and muc 1 ( for confirmation kindly rule out primary from git)
MR1814263,carcinoma right breast.,a) right modified radical mastectomy.b) apical nodes.,a) received in : formalintime to formalin : 4.40pmlaterality : right mrm. total dimensions : medial to lateral 18cm superficial to deep 5cm superior to inferior 13cmskin ellipse : 13x7cm.nipple : normal scar surgical defect : not seen.tumour size : 4.5x3.5x3cm location of tumor : upper outer quardent.margins of tumor : illdefind. deep margin : 0.5cm.muscle : 3x2x0.5cm.adjacent breast : fibrofatty tissue.axillary tail : 11x7x3cm.size of largest node : 1.2x1x1cm.cut surface shows grey brown.b) received single fibrofatty tissue measures 1x1x0.5cm. entire tissue processed.,a) sections show breast parenchyma with tumor infiltrating in the form of tubules and nests composed of round to polygonal cells with high n:c ratio pleomorphic vesicular nucleus prominent nucleolus and scant cytoplasm.mitosis are 1 2 hpf and areas of necrosis are seen.b) sections from apical lymph nodes show 7 lymph nodes free of tumor.,a) right modified radical mastectomy:invasive papillary carcinoma nuclear grade 2.nodal metastases 0 16.histopathologic examination:right modified radical mastectomyhistological type:invasive papillary carcinoma with few foci showing micropapillary features.nuclear grade:2tumor measures maximum dimension 4.5cmlocation of tumor uoq.ductal carcinoma in situ not identified.lymphovascular invasion not identified.perineural invasion not identified.posterior resection margin is fibrofatty tissue.nipple and areola is fibrofatty tissue.lymph nodes: 16 lymph nodes metastasis: 0 (0 16) . pathological stage: pt2n0b) apical nodes:isolated 7 lymph nodes .all are free of tumor (0 7).
MR1814264,right breast lump carcinoma breast.,right breast biopsy.,received 2 grey white linear cores measures 1.5 to 1.8cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring an invasive neoplasm arranged in solid nests glandular pattern amp trabecular. the cells are round with moderate eosinophilic cytoplasm round hyperchromatic nucleus. mitotic figures are seen occasionally stroma is desmoplastic with extensive areas of hemorrhage and sparse mononuclear infiltrates.,right breast biopsy:invasive ductal carcinoma nst grade ii.modified bloom richardson score is 5 9.tubular formation 3nuclear pleomorphism 1mitotic activity 2. 5 9
MR1814266,carcinoma lung.,biopsy form lung lesion.,received multiple grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue processed.,sections studied show lung parenchyma harboring an infiltrating lesion arranged in nests and sheets. the cells are polygonal having abundant eosinophilic cytoplasm hyperchromatic pleomorphic nucleus with prominent nucleoli. mitotic figures are discerned. stroma is desmoplastic with moderately dense lymphoplasmacytic infiltrates.,biopsy form lung lesion:poorly differentiated carcinoma. squamous cell carcinoma. metastatic from breast.suggest ihc.please correlate with clinical and radiological findings.
MR1814268,left breast lump carcinoma breast.,biopsy from left breast.,received multiple grey white linear cores measures 0.5 to 0.8cm . entire tissue processed.,sections studied show fibrous tissue infiltrating lesion arranged in vague tubules and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma is desmoplastic with areas of hemorrhage and necrosis.,biopsy from left breast:invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9.tubular formation 2nuclear pleomorphism 2mitotic activity 2 6 9
MR1814270,right breast lump carcinoma breast.,right breast core biopsy.,received 3 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section shows cores of breast tissue involved by tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. few extracellular pools of mucin are seen.,right breast core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1814303,right breast mass birads highly suspicious of malignancy.,biopsy from right breast mass.,received multiple grey white measures 0.5 1cm. entire tissue processed.,the section shows linear cores of breast parenchyma showing infiltrating by tumor arranged in nests cords and focally in tubules. the tumor cells are round to ovoid with increased n:c ratio hyperchromatic ovoid nuclei and moderate amount of eosinophilic cytoplasm. intervening stroma in desmoplastic and shows hyalinization.,right breast mass core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score 7(3+2+2).
MR1814337,carcinoma left breast.,left modified radical mastectomy.,received in : formalin procedure : modified radical mastectomy laterality : lefttotal dimensions : medial to lateral :19cm superficial to deep : 6cm superior to inferior : 16cmskin ellipse :12x9cmnipple :normal scar surgical defect : not seentumor :single tumor size : 3x3x2cm location of tumor : lower central quadrantmargins of tumor : iil defined deep margin : 0.5cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail : 17x9cmtotal number of nodes : 15size of largest node :1.5x1x1cm cut surface grey brown.,section studied show breast parenchyma harboring an infiltrating lesion arranged in sheets nests and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma is desmoplastic with mild lymphomononuclear cell infiltrates. areas of hemorrhage and necrosis are seen.,left modified radical mastectomy:histological type: invasive ductal carcinoma.grade :2tumor component maximum dimension 3cm.invasive component measures 3cm.modified bloom richardson score is 7 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2lymphovascular invasion is not seenperineural invasion is not seen.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes 10 lymph nodes metastasis 0 (0 10).pathological stage pt2n0summary:invasive ductal carcinoma left breasttumor grade 2lymph nodes status 0 10.
MR1814362,left breast mass carcinoma breast.,left breast mass biopsy.,received 4 grey white linear cores measures 1 1.3cm. entire tissue processed.,section show linear cores of tumor composed of round to polygonal cells arranged in nests and tubules. these cells show moderate pleomorphic high n c ratio vesicular nucleus prominent nucleolus and mitosis 6 8 10 hpf. stroma shows desmoplasia and lymphomononuclear infiltrate,left breast mm biopsy:invasive ductal carcinoma grade 2. modified bloom richard son score is 7(3+2+2).
MR1814372,carcinoma right breast.,right modified radical mastectomy post nact.,received in : 10 nbf.procedure : right modified radical mastectomy post nact.laterality : right total dimensions : medial to lateral 18cm superficial to deep 6cm superior to inferior 12cm.skin ellipse : 12x6cm. nipple : normal scar surgical defect : absent.tumor : single.tumour size : 1.2x1x1cm. location of tumor : lower inner quadrant.margins of tumor : illdefined. deep margin : 1.3cm.muscle : absent adjacent breast : fibrofatty tissue. axillary tail : 5x5x5cm.size of largest node : 1.2x1x1cm. cut surface shows deposit,sections show tumor infiltrating breast parenchyma composed of sheets nests and cords of polygonal cells with pleomorphic hyperchromatic nucleus and prominent nucleolus. areas of necrosis seen. stroma shows fibrosis and hyalinisation and focal areas of calcification present.,right modified radical mastectomy post nact.histological type: invasive ductal carcinoma nst.grade: 2tumor measures maximum dimension 1.2cmmodified br score is 6 9tubule formation: 3nuclear pleomorphism: 2mitotic figures: 1ductal carcinoma in situ is not identified.lymphovascular invasion is present.perineural invasion is not identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: 11 lymph nodes metastasis:4 (4 11).perinodal extension present.pathological stage: ypt1n2a.summary:invasive ductal carcinoma nst right breast.tumor grade: 2lymphnode status:4 11
MR1814408,left breast lump carcinoma breast.,left breast lump core biopsy.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1814429,left breast lump carcinoma breast,biopsy from left breast lump.,received 3 grey white linear cores measures 1 1.2cm. entire tissue processed.,section show linear cores of tissue composed of nests and cords of large polygonal with moderate pleomorphism. these cells show high n c ratio hyperchromatic irregular nucleus and scant to moderate cytoplasm. mitosis are 2 3 10hpf. stroma shows desmoplasia and mild lymphomononuclear infiltrate.,biopsy from left breast lump:invasive carcinoma (nst) grade 2.modified bloom richardson score is 6 9(3+1+2).
MR1814430,carcinoma right breast.,wide excision : conservative breast surgery.,a) received fibrofatty tissue measures 3x2x1cm. isolated 3 lymph nodes.largest measures 1.2x1x0.5cm. cut surface shows fatty infiltration. entire tissue processed.b) received wide local excision specimen measures 8x6x4.5cm.skin ellipse measures 4x1cm.serial sections reveal ill defined lesion measures 4.0x3.4x3.1cm.distance from the margins:superior margin 1cm.inferior margin 0.4cm.medial margin 1cm.lateral margin 1.2cm.deep margin 1cm.c) received single fibrofatty tissue measures 2x1x1cm. cut surface is unremarkable.,tumor :multiple sections from the tumor shows pleomorphic cells with hyperchroamtic nucleus with scanty cytoplasm. the cells are arranged diffusely in clumps and glands. tubular formation less than 10 (3)mitotic figures 6 10 (2).nuclear pleomorphism (2).modified bloom richardson score 7 9.nuclear grade ii.lymphovascular invasion is not identified.perineural invasion is not identified.ductal carcinoma in situ.residual margin superior few ducts show epithelial hyperplasia close to margin.inferior margin free of tumor.medial margin free of tumor.lateral margin free of tumor.deep margin free of tumor.revised superior margin free of tumor..sentinel lymph nodes:3 nodes no deposit of tumor.,wide excision : conservative breast surgery:invasive ductal carcinomanuclear grade ii.maximum dimension of tumor 4x3.4x3.1cm.invasive carcinoma measures 4cm.ductal carcinoma in situ not identified.lymphovascular invasion not identified.perineural invasion not identified.resected margins : inferior medial lateral deep margins are free of tumor.sentinel lymphnodes: 3 nodes isolated are free of tumor 0 3.pathological stage : pt2n0
MR1814431,left breast lump carcinoma breast,biopsy from left breast lump,received 4 grey white linear cores measures 1 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma with lesion infiltrating in the form of nests and cords composed of polygonal cells with high n c ratio hyperchromatic nucleus and moderate cytoplasm. there is moderate pleomorphic and mitosis 1 2 hpf . stroma shows desmoplasia and lymphomononuclear infiltrate.,biopsy from left breast lump:invasive ductal carcinoma (nst) grade 2.modified bloom richardson score is 6 9(3+1+2).
MR1814470,complaint of left breast.,biopsy from left breast mass.,received multiple grey white soft tissue bits measures 0.4x0.3x0.2cm. entire tissue processed.,section studied shows fragmentary of bits of tumor tissue arranged in glandular pattern and sheets. the cells are round with clear to eosinophilic cytoplasm round hyperchromatic nucleus and prominent nucleoli moderate nuclear pleomorphism noted.occasional mitotic figures seen. stroma is desmoplastic and infiltrated by dense lymphocytes and plasma cells. areas of necrosis seen.,biopsy from left breast mass:invasive carcinoma nst ductal originmodified bloom richardson score is 7 9(3+2+2) grade 2large areas of necrosis see.
MR1814482,left breast birads 5,biopsy from left breast lump.,received 4 grey white linear cores measures 1.5 2cm. entire tissue processed.,linear core studied show breast parenchyma harboring lesion arranged in sheets trabecular. lesional cells have pleomorphic vesicular nuclei prominent nucleoli high n c ratio scanty eosinophilic cytoplasm. adjacent stroma show desmoplastic change and extensive area of necrosis also noted. brisk mitotic activity discerned.,biopsy from left breast lump:invasive carcinoma of ductal origin nst grade 3.modified bloom richardson score is 8 9 (3+3+2).
MR1814483,carcinoma right breast.,a) right sentinel lymph node biopsy.b) right breast conservative surgery.,a) received fibrofatty tissue measures 3.8x3.5x2cmlymph nodes measures 1x0.8x0.5cm.b) received wile local excision right breast measures 12.7x21.7x2.5cm on cut section identified a single firm mass measures 1.8x1.5x1.5cm margins are ill definedskin ellipse measures 11x3.5cmpuckering over nipple areola is seendistance from margins:superior margins 1.5cminferior margin 2cmmedial margin 2.5cmlateral margin 9cmdeep margin 5.5cm,a) sentinel lymph node : 2 lymph nodes no metastatic deposit of tumor.b) tumor is composed pleomorphic cells with hyperchromatic nucleus with eosinophilic cytoplasm tumor formation is less than 10 3mitotic figures 2 anaplasia 2ductal carcinoma in situ solid cystmodified bloom richardson score is 7 9nuclear grade iilymphovascular invasion not identifiedperineural invasion not identifiedthe section show from the nipple and areola shows pagets disease of nipple and areolaall resected margins are free the tumor.,b) wide local excision right breast conservative surgery:maximum dimension tumor is 1.8x1.5x1.5cm.invasive ductal carcinoma measures 1.5cm.nuclear grade iiductal carcinoma in situ 0.3cm low grade lymphovascular invasion not identifiednipple and areola pagets disease presentall resected margins are free of tumor. a) right sentinel lymph node : 2 lymph nodes no metastatic deposit of tumor.
MR1814501,right breast lesion carcinoma breast.,biopsy from right breast lesion.,received 4grey white linear cores measures 1 1.5cm. entire tissue processed.,section studied show linear cores fibrocollagenous tissue harboring an invasive neoplasm arranged in glandular trabecuclar pattern. the lesional cells are polygonal with vacuolated to eosinophilic cytoplasm round nucleus with prominent nucleoli mid nuclear pleomorphism and infiltrated by lymphocytes plasma cells and histiocytes. areas of hemorrhage.,biopsy from right breast lesion:invasive carcinoma nst ductal origin.modified bloom richardson score is 2+1+2 5 9 grade ii.
MR1814509,left breast lump possibility carcinoma breast.,biopsy from left breast lump.,received 3 grey white linear cores measures 0.5 1cm. entire tissue processed.,section studied shows linear cores of breast parenchyma fibroadipose tissue harboring an invasive neoplasm arranged in glandular pattern trabecular and cords. lesional cells are round with moderate eosinophilic cytoplasm pleomorphic hyperchromatic nucleus. mitotic figures are seen. occasionally. stroma is demosplastic and infiltrated by dense lymphocytes and plasma cells,biopsy from left breast lump:invasive carcinoma no special type.modified bloom richardson score is 3+2+1 6 9 grade ii.
MR1814513,left breast mass suggestive of malignancy,biopsy from left breast lump.,received 4 grey white linear cores measures 1.5 1.8cm. entire tissue processed.,section show linear cores of breast parenchyma with lesion composed of nests and cords of round to oval cells with hyperchromatic nucleus and scant to moderate cytoplasm foci of solid and cribriform ductal carcinoma in situ are noted. mitosis are 3 4 10 hpf with foci of necrosis stroma shows lymphomononuclear infiltrate.,biopsy from left breast mass:invasive ductal carcinoma (nst) with ductal carcinoma in situ grade 2.modified bloom richardson score is 6 9(3+1+2).
MR1814517,carcinoma right breast post nact.,a) right breast wide local excision post nact.b) right axillary sentinel lymph node. (hot and blue node).c) right axillary sentinel lymph node. (hot node).d) revised superior margin.e) revised deep margin.,received single fibrofatty tissue measuring 5.5x4x3.5cma) grossly no tumor identified.only fibrotic areas seen.distance from margins:superior margin 1cm.inferior margin 1cm.medial margin 2cm.lateral margin 2.5cm.deep margin 1cm.b) received 1 lymph node measures 3x2x2cm. cut surface is fatty infiltration. entire tissue processed.c) received fibrofatty tissue measures 3x2x2cm.largest lymph node measures 1.5x0.5x0.5cm. entire tissue processed.d) received fibrofatty tissue measures 6x3x1.5cm. inked surface identified away from tumor.e) received fibrofatty tissue measures 2x1x0.5cm. inked surface identified measures 1x0.2cm. entire tissue processed.,a) sections from right breast wide local excision post nact shows no residual viable tumor. extensive fibrosis hyalinisation adenosis with epithelial hyperplasia. no atypia seen. stromal shows mild inflammatory infiltrates composed of lymphocytes histiocytes and plasma cells. all the resected margins are free of tumor. (superior inferior medial lateral and deep). revised superior and revised deep are free of tumor.b) identified one lymph node. it is free of tumor (0 1).c) identified five lymph nodes (frozen+paraffin). all are free of tumor (0 5).d) section shows fibroadipose tissue. it is free of tumor.e) section shows fibrocollagenous tissue adipose tissue. it is free of tumor.,a) right breast wide local excision post nact:no residual viable tumor seen.therapy related changes only.all the resected margins (superior inferior medial lateral and deep) are free of tumor.b) right axillary sentinel lymph node. (hot and blue node):identified one lymph node. it is free of tumor (0 1).c) right axillary sentinel lymph node. (hot node):identified five lymph nodes (frozen+paraffin). all are free of tumor (0 5).d) revised superior margin:free if tumor.e) revised deep margin:free of tumor.
MR1814533,carcinoma right breast post nact.,right modified radical mastectomy.,received in : formalinprocedure : modified radical mestectomy post nact laterality : right total dimensions : medial to lateral :19cm superficial to deep : 6cm superior to inferior :15cmskin ellipse : 11x6cm nipple : normal scar surgical defect :notumor : singletumour size : 3x2.8x2cm location of tumor : upper outer quadrant 10 clock position. deep margin :0.8cmmuscle : absentadjacent breast : fibrofattyaxillary tail :11x7x2cm size of largest node :1.2x1.2x1cm. cut surface fatty infiltration.well circumscribed lesion measures 1.5x1.5x1.5cm seen.,section studied shows residual viable tumor . tumor tissue is arranged in glandular pattern nests and trabeculae. the lesional cells are round to polygonal with moderate eosinophilic cytoplasm round moderately pleomorphic nucleus prominent nucleoli. adjacent breast shows ductal carcinoma in situ in solid cribriform and comedo pattern. mitotic figures are discerned. stroma shows desmoplasia hyalinisation inflammatory infiltrate. areas of necrosis identified. lymphovascular and perineural invasion identified.section studied from another mass shows well circumscribed lesion shows glands and stroma glands of varying sizes composed slit like with stromal proliferation glands are lined by epithelial and myoepithelial layers. few showing epithelial hyperplasia. no atypia is seen. stroma shows dense fibrocollagenous tissue. suggestive of intracanalicular tibroadenoma.,right modified radical mastectomy post nact.histological type:residual viable tumor present invasive ductal carcinoma.grade:2tumor measures maximum dimension 3cminvasive component measures 2cmductal carcinoma in situ measures 1cmmodified br score is7 9tubule formation: 3 nuclear pleomorphism: 2mitotic figures:2 ductal carcinoma in situ seen in comedo solid and cribriform pattern nuclear grade 3 lymphovascular invasion identified perineural invasion identifiedposterior resection margin is free of tumornipple and areola is unremarkable and free of tumor.lymph nodes: 16 lymph nodes metastasis: 0(0 16). pathological stage:ypt2n0 summary: invasive ductal carcinoma right breast post nact.tumor grade:2lymph node status: identified 16 lymph nodes none show metastatic deposit of tumor.(0 16)also seen well circumscribed lesion in lower inner quadrant measures 1.5cm in greatest dimension suggestive of fibroadenoma.
MR1814556,right breast mass carcinoma breast,right breast mass biopsy.,received 4 grey white linear cores measures 1.2 1.8cm. entire tissue processed.,the section shows linear cores of breast parenchyma showing tumor infiltrating in cords and nests . the tumor cells are round to ovoid with high n c ratio hyperchromatic ovoid nuclei and moderate cytoplasm. intervening stroma shows dense desmoplastic reaction.,right breast mass biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score7(3+2+2).
MR1814591,carcinoma right breast.,a) right breast lump wide local excision.b) right sentinel lymph node biopsy blue + hot nodec) right sentinel lymph node biopsy hot nodes.,a) received skin covered soft tissue measures 8x7.5x3.5cmskin ellipse measures 8x7.5x3.5cmskin surface unremarkableon cut opening identified ill defined firm grey white lesion measures 2x1x1cm distance from margins:superior margin: 2cminferior margin : 1.5cmmedial margin : 1.5cmlateral margin : 0.8cmdeep margin : 1.5cmb) received fibrofatty tissue measures 1x8x0.7cmlargest lymph node measures 1x0.5x0.4cmc) received fibrofatty tissue measures 1x0.8x0.7cm.,section studied shows breast parenchyma harboring an infiltrating lesion arranged in nests and tubules. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma is desmoplastic with mild lymphomononuclear cell infiltrate. areas of hemorrhage and necrosis are seen.,a) right breast lump wide local excision:invasive ductal carcinoma grade 2tubule formation :2nuclear pleomorphism :2mitotic figures :2 mbr score is 6 9tumor measures 2cm in greatest dimensioninvasive component measures 2cm in greatest dimensionlymphovascular invasion and perineural invasion are not seenductal carcinoma in situ is not identified.all margins of resection ( superior inferior medial lateral and deep ) margin are free of tumor.b) right sentinel lymph node biopsy blue + hot node:isolated single lymph node is free of tumor(0 1)c) right sentinel lymph node biopsy hot nodes:isolated two lymph nodes are free of tumor (0 2)pathological stage : pt1n0.
MR1814603,case of left breast carcinoma.,a) left modified radical mastectomy post nact.b) revised base c) interpectoral tissue.,a)received in : formalin procedure : modified radical mastectomy laterality : left total dimensions : medial to lateral :23cm superficial to deep : 7cm superior to inferior : 17cmskin ellipse :19x3cmnipple :normal scar surgical defect : notumor : single tumor size : 2.5x2x1cm location of tumor :upper outer quadrant deep margin : 2cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail : 6x4x2cmsize of largest node :2.5x2x1cm. cut surface grey white deposit seenb) received single fibromuscular measures 2x1x1cmc) received single fibrofatty tissue measures 2x2x1cm,a) section studied shows breast parenchyma harboring an infiltrating lesion arranged in nests sheets and tubules. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma is demsoplastic with areas of fibrosis hemorrhage and necrosis. lympoplasmacytic infiltratre is present surrounding the tumor.,a) left modified radical mastectomy post nact.histological type: residual invasive ductal carcinoma.grade :2tumor component maximum dimension2.5cm.invasive component measures 1.5cm.ductal carcinoma in situ measures 1.0cm.modified bloom richardson score is 7 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2ductal carcinoma in situ solid and comedonecrosis pattern.lymphovascular invasion is seenperineural invasion is seen.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes 12 lymph nodes metastasis 1(1 12). perinodal spread is not seen.b) revised base : free of tumor.c) interpectoral tissue : free of tumor.pathological stage ypt1n1summary:residual invasive ductal carcinoma left breast post nact.tumor grade 2lymph nodes status 1 12 perinodal spread is not seen.
MR1814607,case of right breast carcinoma,a) right sentinel hot nodeb) right sentinel blue + hot nodec) right sentinel node non blue and non hot nodesd) right mastectomy,a) received fibrofatty tissue measures 1.8x1.2x0.5cm lymph nodes measures 0.4x0.4x0.4cm cut surface fatty infiltrate.b) received fibrofatty tissue measures 3x2x1.5cmlymph nodes measures 2x1.1x0.5cm cut surface fatty infiltratec) received fibrofatty tissue measures 2.7x1.4x1.1cm.isolated 1 lymph nodes measures 2.7x1.3x0.6cmcut surface fatty iinfiltration.d) received in : formalin procedure :mastectomy laterality : righttotal dimensions : medial to lateral :13.5cm superficial to deep : 3.5cm superior to inferior : 18cmskin ellipse :11.5x8cmnipple :normal scar surgical defect : identified measures 2.5cm in lengthtumor : grossly no tumor identified fibrosis is seen lesion identified measures 1.2x1x1cm location of tumor :lower medial quadrantmargins of tumor : iildefined deep margin : 0.6cmmuscle : 1x1x0.3cmadjacent breast : fibrofatty tissue axillary tail : absent,d) section studied shows breast parenchyma with extensive areas of desmoplasia hyalinisation with lymphomononuclear cells foamy macrophages and foreign body giant cells.,a) right sentinel hot node:isolated single lymph node is free of tumor (0 1)b) right sentinel blue + hot node:isolated single lymph node is free of tumor (0 1)c) right sentinel node non blue and non hot nodes:isolated single lymph nodes is free of tumor (0 1).d)right mastectomy post lumpectomy:histological type: no residual tumor seen with post lumpectomy changes.ductal carcinoma in situ is not seen.lymphovascular invasion is not seenperineural invasion is not seen.posterior resection margin is free of tumor.nipple and areola is unremarkable.pathological stage yptxn0summary:no residual tumor seen right breast.lymph nodes status 0 3.
MR1814637,complaint of lump in right features highly suggestive of case breast birads v.,biopsy from right breast lump.,received multiple fragmented core measures 0.3 0.5cm. entire tissue processed.,section studied shows fibrous tissue harboring an infiltrating lesion arranged in sheets. the cells are ovoid having moderate hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned (7 8 10 hpf). stroma is desmoplastic with areas of hemorrhage and extensive necrosis,biopsy from right breast lump:invasive carcinoma nst grade 3modified bloom richardson score is 3+2+3 8 9
MR1814642,right breast mass carcinoma breast,biopsy from right breast mass,received 3 grey white linear cores measures 1 1.5cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue with invasive neoplasm arranged in glandular pattern and nests trabecular pattern. the lesional cells are polygonal with moderate eosinophilic to vacuolated cytoplasm round vesicular nucleus and prominent nucleoli stroma is desmoplastic.,biopsy from right breast mass:invasive carcinoma nst grade 2.modified bloom richardson score is 3+1+1 5 9
MR1814695,left breast lump carcinoma breast.,biopsy from left breast.,received 4 grey white linear cores measures 1 1.5cm. entire tissue processed.,section shows linear cores of tumor composed of nests and occasional tubules lined by cuboidal to polygonal cells with pleomorphic hyperchromatic nucleus and moderate cytoplasm. mitosis are 3 4 10hpf. intervening stroma is desmoplastic. modified br score is 6 9tubule formation : 3nuclear pleomorphism : 1mitotic figures : 2 ........... 6 9 ............,left breast lump biopsy :invasive ductal carcinoma (nst) grade 2.
MR1814700,left breast lesion carcinoma breast,biopsy from left breast,received 4 grey white linear cores measures 1 1.5cm. entire tissue processed.,section studied shows fibrocollagenous tissue harboring an invasive neoplasm arranged in lobular glandular pattern nests trabecular. the lesional cells are polygonal with moderate eosinophilic cytoplasm round to oval hyperchromatic nucleus and prominent nucleoli. focus of squamous differentiation is seen. many tumor infiltrating lymphocytes are seen. surrounding the tumor tissue. extensive crush artifacts are noted. areas of hemorrhage and necrosis seen.,biopsy from left breast:invasive carcinoma nst.nuclear grade iii
MR1814702,advanced carcinoma right breast with suspected left scln mets.,right supraclavicular lymphnode.,received single lymphnode measures 0.8 x 0.5x 0.5cm. entire tissue processed.,section shows lymphnode parenchyma with effaced architecture replaced by tumor cells arranged as nests and sheets. the tumor cells are round to polygonal with hyperchromatic pleomorphic nucleus and scant to moderate cytoplasm.there is no evidence of extra nodal extension.,left supraclavicular lymphnode :metastasis in a known case of carcinoma breast.
MR1814705,right breast solid cystic lesion predominantly systic carcinoma breast.,biopsy from right breast mass.,received 4 grey white linear cores measures 0.5 1.2cm. entire tissue processed.,section studied shows linear cores of fibro adipose tissue harboring an invasive neoplasm arranged in granulation pattern nests. the lesional cells are round with high n c ratio scant eosinophilic cytoplasmic round hyperchromatic nucleus showing marked nuclear pleomorphism . mitotic figures are 2 4 10hpf. stroma is desmoplastic and infiltrated by lymphocytes and plasma cells.,right breast massinvasive carcinoma nst ductal origin grade iii.modified bloom richardson score is 3+2+3 8 9.
MR1814781,left breast mass birads iv lesion,biopsy from left breast mass,received 4 grey white linear cores measures 1 1.5cm. entire tissue processed.,section studied shows breast parenchyma with infiltrating neoplasm arranged in glands trabecular cords indian file pattern. the lesional cells are small round scant eosinophilic cytoplasm round hyperchromatic nucleus mild nuclear pleomorphism noted. stroma is desmoplastic infiltrated by lymphocytes and plasma cells.,biopsy from left breast mass:invasive carcinoma nst with lobular features.modified bloom richardson score is 3+1+1 5 9 grade 1.
MR1814796,large mas in right breast,biopsy from right breast mass.,received 3 grey white linear cores measures 0.6 0.7cm. entire tissue processed.,section studied shows invasive neoplasm in desmoplastic stroma. neoplasm arranged in trabecular and cords. the cells are polygonal to round with scant eosinophilic cytoplasm ovoid to elongated hyperchromatic nucleus moderate nuclear pleomorphism noted . few mitotic figures seen loss of crush artifacts are seen.,biopsy from right breast mass:invasive carcinoma nst ductal origin.modified bloom richardson score is 3+2+2 7 9.
MR1814821,carcinoma right breast.,a) right breast wide local excisionb) right sentinel lymph nodes blue +hot nodec) right sentinel lymph nodes hot nodes.,a) received wide local excision specimen measures 6x5x3cm serial section illdefined lesion measures 4.2x3.5x2.6cm.distance from margins:superior margin :4cminferior margin :2cmmedial margin : 3.6cmlateral margin : 3.1cmdeep margin : 1.2cmb) received fibrofatty tissue single lymph nodes measures 2x1x1cmcut surface fatty infiltration seenc) received 4 lymph nodeslargest lymph nodes measures 1x1x0.5cmcut surface fatty infiltration .,a) section studied show breast parenchyma harboring an infiltrating lesion arranged in nests sheets and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. stroma is desmoplastic with mild lymphomononuclear cell infiltrates. areas of hemorrhage and necrosis are seen.,a) right breast wide local excision:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9tubule formation 2nuclear pleomorphism 2mitotic figures 2 6 9 tumor measures 4.2cm in greatest dimensioninvasive component measures 4.2cm in greatest dimensionductal carcinoma in situ is not seenlymphovascular invasion perineural invasion are not seenall margins of resection ( superior inferior medial lateral and deed) are free of tumor.overlying skin is unremarkable.b) right sentinel lymph nodes blue +hot node:isolated single lymph node is free of tumor (0 1).c) right sentinel lymph nodes hot nodes:isolated four lymph node is free of tumor (0 4).pathological stage : pt2n0.
MR1814824,left breast lump possibility carcinoma breast.,biopsy from left breast lump.,received 3 grey white linear cores measures 0.6 0.8cm. entire tissue processed.,section shows linear core biopsy of tumor composed of nests and tubules lined by cuboidal to columnar cells with high n c ratio hyperchromatic pleomorphic nucleus and scant to moderate cytopplasm. intervening stroma shows desmoplasia and lymphomononuclear infiltrate.,biopsy from left breast lump:invasive ductal carcinoma (nst) grade 2.modified bloom richardson score is 7 9(2+2+3).
MR1814836,left breast mass,left breast lump,received multiple linear cores measures 0.8 1cm. entire tissue processed.,section shows linear cores of tumor composed of nests of polygonal cells with high n c ratio hyperchromatic pleomorphic nucleus and scant to moderate cytoplasm. mitosis are 1 2 hpf areas of necrosis and desmoplastic stroma is seen.,left breast lump:invasive ductal carcinoma (nst) grade 3modified bloom richardson score 9 9.
MR1814845,left breast mass carcinoma breast.,biopsy from left breast,received grey white to grey brown linear cores measures 0.6 1.2cm. entire tissue processed.,section studied shows linear cores of invasive neoplasm arranged in glandular pattern nests. the cells are polygonal with abundant eosinophilic cytoplasm pleomorphic hyperchromatic nucleus and prominent nucleoli. stroma is desmoplastic with lymphoplasmacytic infiltrate.,biopsy from left breast:invasive carcinoma ductal origin nstmodified bloom richardson scores is 3+2+3 8 9 grade 3
MR1814860,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 3 grey white linear cores measures 0.3 0.7cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an invasive neoplasm arranged in glandular pattern trabecular . the cells are polygonal with abundant eosinophilic cytoplasm round hyperchromatic nucleus and prominent nucleoli. stroma is desmoplasia.,biopsy from left breast lump:invasive carcinoma nst and ductal origin.modified bloom richardson score is 2+2+2 6 9.
MR1814881,right breast mass carcinoma breast.,biopsy from right breast lump.,received 4 grey white mucinous cores measures 0.8 1cm. entire tissue processed.,section shows cores of breast parenchyma with a lesion arranged as nests and islands of cells floating in pools of mucin. the lesional cells have round to oval hyperchromatic nuclei and moderate eosinophilic cytoplasm. mitotic figures discerned. intervening stroma shows fibrosis.,biopsy from right breast lump:invasive carcinoma with mucinous feature. nuclear grade 1modified bloom richardson score is 5 9tubule formation 3nuclear pleomorphism 1mitotic figures 1 5 9
MR1814885,right breast mass carcinoma breast.,right breast mass core biopsy.,received multiple grey white to grey yellow linear cores measures 0.5 1cm. entire tissue processed.,section shows tumor cells in sheets nests cords and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast mass core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1814901,left breast mass.,left breast mass biopsy.,received 3 grey white linear cores measures 0.8 1.5cm. entire tissue processed.,section studied shows linear cores of infiltrating neoplasm arranged in glandular tubular nests . teh lesional cells are polygonal with abundant clear to eosinophilic cytoplasm pleomorphic nucleus with prominent nucleoli. few cells showing intranuclear inclusion. stroma is desmoplastic and show dense lymphoplasmacytic infiltrates. area of comedonecrosis seen.,left breast mass. biopsy : invasive carcinoma nst ductal origin. modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 8 9 grade iii.
MR1814911,carcinoma right breast.,right modified radical mastectomy.,received in : formalin procedure : modified radical mastectomy laterality : righttotal dimensions : medial to lateral :20cm superficial to deep : 6cm superior to inferior : 15cmskin ellipse :12x10cmnipple :normal scar surgical defect : not seentumor : single tumor size : 3x2.5x2cm location of tumor : lower outer quadrantmargins of tumor : ill defined deep margin : 1.5cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail : 13x8cmsize of largest node :1x0.5x0.5cm. cut surface grey brown.,section studied shows breast parenchyma harboring an infiltrating lesion arranged in nests islands and sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows extensive areas of desmoplasia with areas of hemorrhage and necrosis.,right modified radical mastectomy:histological type: invasive ductal carcinoma.grade :2tumor component maximum dimension 3cm.invasive component measures 3cm.modified bloom richardson score is 7 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2ductal carcinoma in situ not seen.lymphovascular invasion is present.perineural invasion not seen.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes 14 lymph nodes metastasis 1(1 14). perinodal spread is not seen.pathological stage pt2n1summary:invasive ductal carcinoma right breasttumor grade 2lymph nodes status 1 14. perinodal spread not seen.
MR1814912,birads 5 lesion on mamography ductal carcinoma,biopsy from left breast mass,received 6 grey white to grey yellow linear cores measures 1 1.2cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring an invasive neoplasm arranged in glandular pattern nests and trabecular. the cells show moderate eosinophilic cytoplasm round hyperchromatic nucleus mild nuclear pleomorphism and prominent nucleoli. stroma is desmoplastic and shows dense aggregates of lymphocytes and plasma cells. foci of necrosis seen.,biopsy from left breast mass:invasive carcinoma nst ductal originmodified bloom richardson score is 2+2+2+ 6 9.foci of necrosis seen.
MR1814914,right breast mass carcinoma breast,biopsy from right breast lump.,received 3 grey white linear cores measures 1.2 1.4cm. entire tissue processed,section studied shows linear cores of invasive neoplasm arranged in sheets lobules and glandular pattern. the cells are round to polygonal with abundant eosinophilic cytoplasm few showing vacuolation moderately pleomorphic hyperchromatic nucleus and prominent nucleoli. stroma is desmoplastic shows lymphoplasmacytic infiltrates. areas of necrosis seen.,biopsy from right breast lump:invasive carcinoma nst ductal origin.modified bloom richardson score is 3+2+2 7 9 grade ii
MR1814918,right breast mass birads 5,biopsy from right breast mass.,received 3 grey white to grey brown linear cores measures 0.5 0.8cm. entire tissue processed.,section studied shows extensive areas of necrosis with invasion neoplasm in desmoplastic stroma. the neoplastic cells are round to polygonal with moderate eosinophilic cytoplasm nucleus and prominent nucleoli. occasional mitotic figures seen. pools of mucin seen. foci of necrosis present.,biopsy from right breast mass:invasive carcinoma with mucinous differentiation modified bloom richardson score 2+2+2 6 9 grade ii.
MR1814922,carcinoma right breast lump.,right modified radical mastectomy.,received in : formalin procedure : modified radical mastectomy post lumpectomy. laterality : righttotal dimensions : medial to lateral :22cm superficial to deep : 4cm superior to inferior : 16cmskin ellipse :12x10cmnipple :normal scar surgical defect : upper outer quadranttumor : single tumor size : 4x4x3cm location of tumor : central quadrantmargins of tumor : iildefined deep margin : 3cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail : 13x6x3total number of nodes : 17 nodessize of largest node : 2x1x0.5cm cut surface grey white.,tumor bed shows fibrotic and necrotic areas and foreign body giant cells.,right modified radical mastectomy:no residual viable tumor presentposterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes 17 lymph nodes metastasis 17 nodes no metastatic deposit of tumor. 0 17pathological stage ptxn0.summary:right modified radical mastectomy post lumpectomy.no residual viable tumor fibrotic and necrotic areasnodal metastasis 17 nodes show no metastatic deposit of tumor 0 17.
MR1814993,left breast lump carcinoma breast.,left breast mass biopsy.,received 5 grey white linear cores 1 to 1.5 cm. entire tissue processed.,linear cores of breast tissue harboring a tumor arranged as tubules cluster and cords. the lining epithelial cells are cuboidal exhibits moderate pleomorphism hyperchromatic nucleus moderate amount of cytoplasm. intervening stroma is scant.,left breast mass biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1815017,left breast mass.,left breast mass biopsy.,received 4 grey white linear cores measures 0.2 to 0.8 cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring an invasive neoplasm in desmoplastic stroma. the cells are round with moderate clear to eosinophilic cytoplasm round moderately pleomorphic nucleus prominent nucleoli. mitotic figures seen. there is dense lymphoplasmacytic infiltrates stroma. areas of necrosis.,left breast mass biopsy : invasive carcinoma nst. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 grade ii.
MR1815020,right breast lesion.,a) right breast lesion(upper inner quadrant.)b) right breast mass.,a) received 5 grey white linear cores measures 0.5 to 1cm. entire tissue processed. b) received grey white linear cores measures 0.3 to 0.4cm. entire tissue processed.,a) section shows cores of breast parenchyma with a lesion arranged in sheets papillary and tubular pattern. the lining cells are columnar with round to oval hyperchromatic nuclei and moderate cytoplasm. frequent mitosis noted. extracellular mucin is noted. stroma shows desmoplasia and lymphocytic infiltrate. b) section shows a single small core of sclerotic tissue. no ductal elements noted.,a) right breast lesion(upper inner quadrant.)suggestive of invasive carcinoma grade 2. modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 b) right breast (5 8 0 clock)only scant volume of sclerotic tissue seen. not adequate for conclusive opinion.
MR1815030,right breast lump possibility of carcinoma breast.,right breast lump biopsy.,received 4 grey linear cores 0.8 to 1.5cm. entire tissue processed.,multiple linear cores of breast tissue harboring a tumor arranged in sheets nest and cords. the cells are round to oval with hyperchromatic nuclei abundant eosinophilic cytoplasm. intervening stroma shows lymphoplasmacytic infiltrate.,right breast lump biopsy :invasive carcinoma nst grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1815037,right breast mass.,right breast mass biopsy.,received 3 grey linear core measures 0.5 to 0.8cm. entire tissue processed.,right breast mass :section studied show linear cores of fibrocollagenous tissue harboring an invasive neoplasm arranged in sheets glandular pattern trabecular. the cells have moderate cytoplasm round hyperchromatic nucleus and prominent nucleoli. marked nuclear inclusions. few multinucleated cells are seen. mitotic figures are seen. stroma is desmoplastic with inflammatory infiltrates and thin walled blood vessel. areas of necrosis and hemorrhage seen.,right breast mass biopsy :invasive carcinoma ductal origin nst. modified bloom richardson score is 9 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 3 9 9 grade iii.
MR1815057,left breast lump possibility of carcinoma breast.,left breast mass biopsy.,received 3 grey white linear cores measures 1 1.5cm. entire tissue processed.,section studied shows linear cores of invasive neoplasm arranged in lobules separated by fibrous septae nests the lesional cells are polygonal with abundant vacuolated to eosinophilic cytoplasm round to oval nucleus prominent nucleoli. marked nuclear pleomorphism noted. mitotic figures are seen with few atypical forms. stroma is desmoplastic. areas of necrosis seen.,left breast mass biopsy :invasive carcinoma nst. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1815058,carcinoma breast,a)left breast wide local excision post lumpectomy.b) left axillary dissection.,a) received skin covered soft tissue mass measures 7x5x4cmskin ellipse measures 5x1cm surface of skin is unremarkable.cut surface grey white ill defined lesion measures 1.5x1.5x1cmdistance from respective margins:superior margin : 1.5cminferior margin : 1.5cmmedial margin : 1.5cmlateral margin : 2cmdeep margin : 2.5cmskin :2.5cmb) received fibrofatty tissue measures 7x4x3cmlargest measures 0.7x0.5x0.4cmcut surface grey brown.,a) section studied show breast parenchyma with extensive areas of hyalinisation and firosis interspersed are ducts of varying size lined by inner epithelial and an outer myoepithelial layer with no atypia. stroma shows proliferating blood vessels with moderately dense lymphomononuclear cell infiltrate. very tiny foci of atypical cells seen in the frozen section . however ffpe section do not show tumor focus.,a)left breast wide local excision post lumpectomy:very small focus of residual tumor accounting to less than 2mm seen in frozen sectionlymphovascular invasion and perineural invasion are not seen.ductal carcinoma in situ is not seen.all margins ( superior inferior medial lateral and deep ) are free of tumorb) left axillary dissection:all isolated ten lymph nodes are free of tumor (0 10)note: ihc for hormonal status may not be possible as tumor is lost in the representative block.
MR1815067,right breast mass.,right breast mass biopsy.,received 3 grey whit linear core measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast tissue harboring a neoplasm arranged in tubules and cords. the cells are round to oval with hyperchromatic nuclei abundant eosinophilic cytoplasm. adjacent stroma shows mild lymphocyte infiltrate. mitotic figures noted.,right breast mass biopsy :suggestive of invasive ductal carcinoma grade 1.modified bloom richardson score is 4 9tubule formation : 2nuclear pleomorphism : 1mitotic figures : 1 4 9
MR1815093,mass in left breast highly suggestive of malignancy birads 5.,left breast core biopsy.,received 5 grey white cores measures 0.5 to 1cm. entire tissue processed.,section shows tumor cells in sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1815147,right breast mass.,biopsy from right breast mass.,received 5 grey white linear core measures 0.5 to 1cm. entire tissue processed.,section show linear cores of breast parenchyma with invasive tumor composed of nests and cords of round to polygonal cells with high n:c ratio hyperchromatic pleomorphic nucleus and scant to moderate cytoplasm. mitotic are seen 2 3 10hpf. stroma shows desmoplastic and dense lymphomononuclear infiltrate.,invasive carcinoma with lobular features. grade 2. modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1815177,carcinoma left breast ( post lumpectory),a) wide local excision left breastb) left sentinel nodes blue+ hot node c) hot node,a) lumpectomy left breast with skin measures 11.4x6.5x3.6cmskin ellipse measures 8.6x2.2 cmsurface of skin shows scar measure 3.5cm on serial cut grey white ill defined single lesion measures 0.7x0.7x0.5cmdistance from margins:superior margins :1.4cminferior margins : 2.5cmmedial margin : 3.6cmlateral margin : 5.5cmdeep margin : 1cmb) blue +hot node:received fibrofatty tissue measures 3.7x1.6x1.2cmisolated 3 lymph nodes largest lymph node measures 1.3x1.3x1cm.cut surface fatty infiltrated.c)hot node:received fibrofatty tissue measures 1x1x0.5cm isolated 1 lymph node measures 0.5x0.5x0.5cm.,section show breast parenchyma harboring a tumor with cells arranged in sheets and occasional tubules. the cells have moderate eosinophilic cytoplasm pleomorphic round to oval vesicular nuclei with prominent nucleoli. brisk mitotic activity noted. (3 5 hpf). surrounding stroma is desmoplastic with lymphomononuclear infiltration. adjacent breast parenchyma shows ductal carcinoma in situ high grade( solid and comedo type).,a) wide local excision left breast: status post lumpectomyinvasive ductal carcinoma nstresidual tumor status post lumpectomymodified bloom richardson score is 8 9 grade iii(3+3+2 8)tumor measuring lt 1 cm in greatest dimensionductal carcinoma in situ high grade with comedonecrosis seen.resected margin are free of tumor.b) left sentinel nodes left axilla:blue +hot node (0 5)c) hot nodes (0 2)7 of 7 nodes are free of tumorpathological stage. : pt1n0mx(r2)
MR1815187,right breast mass carcinoma breast.,right breast mass biopsy.,received 3 grey white linear core measures 1 to 1.5. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an invasive neoplasm arranged in glandular pattern nests trabecula. the cells are polygonal with clear to eosinophilic cytoplasm round hyperchromatic nucleus. moderate nuclear pleomorphism noted. stroma is desmoplastic and shows inflammatory infiltrates. areas of necrosis noted.,right breast mass :invasive carcinoma ductal origin nst.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 areas of necrosis seen.
MR1815191,right breast lump carcinoma breast.,right breast lump.,received 4 grey linear core measures 0.5 to 0.8cm. entire tissue processed.,section studied shows linear cores of tumor tissue arranged in glandular pattern trabecular cords nests. the celsl are round with scant eosinophilic cytoplasm round hyperchromatic nucleus mild nuclear pleomorphism noted. mitotic figures are sparse. stroma is desmoplastic.,right breast lump :invasive carcinoma ductal origin nst grade 1modified bloom richardson score is 5 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9
MR1815200,left breast mass.,left breast mass biopsy.,received 4 grey white liner core measures 0.3 to 0.8cm. entire tissue processed.,section studied shows fibroadipose tissue harboring an invasive neoplasm arranged in sheets glandular trabecular and cords. the cells are round to with moderate eosinophilic cytoplasm pleomorphic hyperchromatic nucleus. mitotic figures are 10 12 10hpf. stroma is desmoplastic and shows inflammatory infiltrates. areas of hemorrhage and necrosis noted.,left breast mass :invasive carcinoma ductal origin nst.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1815204,swelling right breast.,right breast core biopsy.,received 3 grey white linear core measures 0.6 to 0.8cm. entire tissue processed.,section shows tumor cells in sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1815219,left breast mass.,biopsy from left breast.,received 4 grey white linear core measures 0.8 to 1.5cm. entire tissue processed.,linear cores of breast parenchyma harboring a neoplasm arranged as tubules and clusters. the neoplastic cells have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma shows lymphocytic infiltrate.,biopsy from left breast. invasive carcinomamodified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 grade 2.
MR1815266,left breast mass carcinoma breast.,biopsy from left breast mass.,received 4 grey white linear core measures 0.8 to 1.3cm. entire tissue processed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1815279,case of right breast carcinoma,a) right breast conservative surgery post lumpectomyb) revised basec) revised inferior margind) revised superior margine) right axillary dissection,a) received lumpectomy with skin covered tissue measures 7.5x2.7x2.5cmskin ellipse measures 7x0.8cmcut surface cystic measures 4x1.5x0.2cmdistance from margins:superior margin: 0.65cminferior margin : 0.7cmmedial margin : 0.7cmlateral margin : 0.7cmdeep margin :0.8cmb) received single fibrofatty tissue measures 2.1x1.5x0.5cm.c) received single fibrofatty tissue measures 4.5x2.5x2cm.d) received single fibrofatty tissue measures 3x1.8x1.5cme) received multiple fibrofatty tissue measures 7.5x4x2cmlargest lymph node measures 1.7x1.7x0.5cm. cut surface unremarkable.,section studied shows breast parenchyma with stromal edema fibrosis and aggregates of lymphocytes plasma cells histiocytes and giant cells. no evidence of atypia malignancy noted in the material submitted.,a) right breast conservative surgery post lumpectomy:no evidence of residual tumor seen ductal carcinoma in situ not seen.lymphovascular invasion and perineural invasion are not seenall margins (superior inferior medial lateral and deep) are free of tumor.b) revised base: free of tumorc) revised inferior margin: free of tumord) revised superior margin: free of tumore) right axillary dissection:isolated sixteen lymph nodes are free of tumor.conclusion:breast conservation surgery:no residual tumor presentall resected margin are free of tumor including revised base inferior superior margins are free of tumorlymph nodes 16 nodes no deposit of tumor.
MR1815306,case of right breast lump.,right breast lump core biopsy.,received 5 grey white linear core measures 0.3 to 1cm. entire tissue processed.,section shows tumor cells in sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1815312,right breast mass.,biopsy from right breast mass.,received 5 grey white linear core measures 0.5 to 1.2cm. entire tissue processed.,section show fibroadipose tissue harboring an invasive neoplasm arranged in nests and cords composed of round to polygonal cells with marked pleomorphism. these cells show high n:c ratio vesicular nucleus prominent nucleus and scant to moderate eosinophilic to clear cytoplasm. mitosis are 5 6 hpf. foci of necrosis are seen. stroma shows desmoplasia with lymphomononuclear and neutrophilic infiltrate.,invasive carcinoma ductal origin (nst) grade 3. modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1815366,case of right breast lump.,biopsy from right breast lump.,received 5 grey white linear core measures 0.3 to 1cm. entire tissue processed.,section studied shows breast parenchyma harboring invasive neoplasm arranged in glandular pattern nests trabecular. the cells are round with moderate eosinophilic cytoplasm round hyperchromatic nucleus and few showing prominent nucleoli. stroma is desmoplastic. interspersed are dense collection of lymphocytes and plasma cells. areas of necrosis seen.,right breast lump biopsy :invasive carcinoma ductal origin nst grade ii. modified bloom richardson score is 5 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9
MR1815371,right breast lump.,right breast lump biopsy.,received 4 grey white linear core measures 0.8 to 1.5cm. entire tissue processed.,section shows linear core of breast parenchyma harboring an invasive lesion. the lesion shows round to polygonal cells with hyperchromatic pleomorphic nucleus and scant moderate cytoplasm arranged as nests trabecular and tubules. multinucleated and bizarre tumor cells are seen. mitotis are 2 3 hpf. stroma shows desmoplasia.,right breast lump biopsy :invasive carcinoma ductal origin nst. grade 3.modified bloom richardson score is 9 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 3 9 9
MR1815376,case of right breast lump.,right breast lesion from biopsy.,received 4 grey brown to grey white linear core measures 1 to 1.3cm. entire tissue processed.,section studied shows linear cores of infiltrating lesion arranged in glandular sheets nests trabecular. the lesional cells are round to oval with scant eosinophilic cytoplasm pleomorphic hyperchromatic nucleus few showing prominent nucleoli. intranuclear inclusions are seen in some cells. mitotic figures are 10 12 10hpf. stroma shows dense lymphoplasmacytic infiltrates and desmoplasia. area of necrosis seen.,right breast lesion. invasive carcinoma ductal nst. grade iii. modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1815381,lump right breast,right breast wide local excision.,received lumpectomy specimen measures 6.5x5.5x4cmcut surface shows grey white ill defined mass measures 3x2.5x1cmcut surface shows areas of desmoplasia.distance from margins:superior margins 1.8cminferior margin :1.5cmmedial margin : 0.2cmlateral margin : 0.2cmdeep margin : 0.2cm,tumor is composed of pleomorphic cells with hyperchromatic nucleus with eosinophilic cytoplasm. tumor cells are present in diffuse pattern with pleomorphic hyperchromatic nucleus with eosinophilic cytoplasm. tubular formation 3 mitotic figures 2 anaplasia 2ductal carcinoma in situ present cribriform and comedonecrosis.lymphovascular invasion not identified.perineural invasion not identified.resected margins:superior margin free of tumorinferior margin free of tumormedial and lateral margins are close (0.2cm) from tumor however the inked margins are free of tumordeep margin shows a small clump of ductal carcinoma however the inked margin is free of tumor,right breast wide local excision :maximum dimension of tumor is 3x2.5cminvasive ductal carcinoma measuring 2.2cm.ductal carcinoma in situ measure 0.8cm.lymphovascular invasion not identified.resected margins :all the inked margins are free of tumor.pathological stage: pt2.
MR1815448,carcinoma right breast,right modified radical mastectomy,received in : formalinprocedure : right modified radical mastectomy laterality : right total dimensions : medial to lateral :21cm superficial to deep :5cm superior to inferior:19cmskin ellipse : 16x12cm nipple : normal scar surgical defect :not see4ntumor : singletumour size : 2.6x2x2cm location of tumor : upper outer quadrant margins of tumor : ill defineddeep margin :0.5cmmuscle :absentadjacent breast : fibrofatty tissueaxillay tail : 8x6x2.5cm,section studied shows breast parenchyma harboring an infiltrating lesion arranged in nests islands and sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few mitotic figures are discerned. stroma is desmoplastic with areas of hemorrhage and necrosis.,right modified radical mastectomy:histological type:invasive ductal carcinoma.grade:3tumor measures maximum dimension 2.6cminvasive component measures 2.1 cmductal carcinoma in situ measures 0.5 cmmodified br score is 8 9tubule formation: 3 nuclear pleomorphism: 3mitotic figures: 3 ductal carcinoma in situ solid and cribriform pattern seen.lymphovascular invasion is seen.perineural invasion is not seenposterior resection margin is free of tumornipple and areola is unremarkablelymph nodes: 25 lymph nodes metastasis: 5(5 25)extranodal extension is seen . pathological stage: pt2n2. summary: invasive ductal carcinoma right breast.tumor grade:3lymphnode status:5 nodes show metastatic deposits of tumor out of 25 nodes extranodal extension is seen.
MR1815451,left breast lump.,biopsy from left breast lump.,received 2 grey white linear core measures 0.8 to 1cm. entire tissue processed.,section studied shows ductal carcinoma in situ in solid and cribriform pattern. the luminal cells are round with moderate. clear to eosinophilic cytoplasm moderately pleomorphic hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. areas of necrosis seen. suspicious foci of invasion are seen showing nests of atypical cells and singly lying cells with surrounding extracellular mucin.,left breast lump biopsy. :predominantly ductal carcinoma in situ with suspicious foci of invasion. note : invasion needs to be confirmed on repeat biopsy.
MR1815457,case of left breast lump.,biopsy from left breast lump.,received 4 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring an invasive neoplasm arranged in nests trabecular cords and glandular pattern. the lesional cells are polygonal with abundant eosinophilic cytoplasm round moderately pleomorphic hyperchromatic nucleus and prominent nucleoli. occasional mitotic figures seen. stroma is desmoplastic and shows lymphoplasmacytic infiltrates. areas of necrosis seen. ductal carcinoma in situ is identified (solid type) with apocrine change.,left breast lump biopsy :invasive carcinoma nst with ductal carcinoma in situ.grade ii. modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1815466,left breast lump.,left breast lump biopsy.,received 4 grey white linear core measures 0.8 to 1.3cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in sheets composed of cells with moderate eosinophilic cytoplasm pleomorphic nuclei with marked atypia and increased mitosis. extensive intra and peritumoral lymphoplasmacytic noted.,left breast lump biopsy. invasive carcinoma nst. grade iii.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1815467,case of left breast lump.,left breast lump biopsy.,received 3 grey white linear core measures 0.5 to 1.2cm. entire tissue processed.,the section shows linear cores of breast parenchyma showing infiltration by tumor arranged in sheets and nests. the tumor cells are round to ovoid with high n:c ratio hyperchromatic ovoid to irregular pleomorphic nuclei and moderate amount of cytoplasm. numerous nuclei show prominent nucleoli. large areas of necrosis and mitotic figures are seen. stroma is desmoplastic single focus shows adenosis with myoepithelial hyperplasia.,left breast lump core biopsy : infiltrating carcinoma nst grade 3.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR1815470,left breast mass.,left breast biopsy.,received 3 grey white linear core measures 0.4 to 1cm. entire tissue processed.,section shows cores of fibrous adipose tissue harboring an invasive neoplasm in sheets and nests. the cells show moderate pleomorphism hyperchromatic nuclei and prominent nucleoli .extensive ductal carcinoma in situ with comedo necrosis noted.,left breast biopsy :invasive carcinoma nst. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1815480,carcinoma left breast,a) left sentinel lymph node biopsyb) left modified radical mastectomy.,a) received 3 lymph nodes largest are measures 0.8x0.6x0.5cmcut surface fatty infiltration.b)received in : formalin procedure : modified radical mastectomy laterality : lefttotal dimensions : medial to lateral :13cm superficial to deep : 6cm superior to inferior : 11cmskin ellipse :5x5cmnipple :normal scar surgical defect : not seentumor : single tumor size :2.0x1x0.5cm location of tumor : central quadrantmargins of tumor : iildefined deep margin : 1cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail :absent,b)section studied shows breast parenchyma harboring an infiltrating lesion arranged in nests and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma is desmoplastic with mild lymphomononuclear cell infiltrate.,a) left sentinel lymph node biopsy:isolated three lymph nodes are free of tumor (0 3).b)right modified radical mastectomy:histological type: invasive ductal carcinoma.grade :2tumor component maximum dimension 2.0cm.invasive component measures 1.2cm.ductal carcinoma in situ measures 0.8cm.modified bloom richardson score is 7 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2ductal carcinoma in situ solid cribriform and comedonecrosis pattern is seen.lymphovascular invasion not seenperineural invasion not seen.posterior resection margin is free of tumor.nipple and areola is unremarkable.sentinel lymph nodes 3 nodes no deposit of tumorpathological stage pt1n0summary:invasive ductal carcinoma left breasttumor grade 2lymph nodes status 0 3.
MR1815500,left breast lump carcinoma breast.,left breast lump biopsy.,received 4 grey white to grey brown linear core measures 0.5 1.2cm. entire tissue processed.,section show linear cores of breast parenchyma harboring an invasive lesion comprised of nests of polygonal cells with high n:c ratio vesicular nucleus prominent nucleus with moderate eosinophilic to vacuolated cytoplasm. mitotis discerned. stroma shows desmoplasia and lymphomononuclear infiltrate.,left breast lump biopsy. :invasive carcinoma no special type grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1815524,right breast lump.,right breast lump core biopsy.,received 4 grey white linear core measures 0.5 to 1cm entire tissue processed.,the section show linear cores of breast parenchyma showing tumor infiltrating in tubules nests and cords. the tumor cells are round to polygonal with high n:c ritio hyperchromatic ovoid nuclei and moderate amount of eosinophilic cytoplasm. occasional prominent nucleoli are seen. intervening stroma is desmoplastic occasional lymphoid aggregates is seen.,features suggestive of invasive carcinoma nst grade ii.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1815529,carcinoma right breast.,a) right breast lumpectomy (post lumpectomy status).b) hot node.c) blue + hot node.,a) received lumpectomy measures 6x4x3cm. skin measures 4x4x0.6cm show linear scar measures 3.8cm.serial section revealed illdefined grey white fibrotic areas measures 0.2x1x0.5cm.distance from the margins:superior margin 1cm.inferior margin 1cm.medial margin 2cm.lateral margin 2cm.deep margin 1.1cm.b) received single node measures 0.5x0.4x0.4cm. entire tissue processed.c) received single node measures 1x0.5x0.5cm. cut surface shows fatty infiltrate seen.,multiple sections from the fibrotic areas shows extensive fat necrosis lymphohistiocytic aggregates and foreign body giant cells reaction. adjacent breast show atropic ducts. no evidence of residual tumor seen.,a) right breast lumpectomy (post lumpectomy status):no residual tumor seen.ductal carcinoma in situ not identified.lymphovascular invasion not identified.perineural invasion not identified.all resected margins are free of tumor.sentinel lymph node dissection.b) hot node:1 node isolated is free of tumor (0 1).c) blue + hot node:1 node isolated is free of tumor (0 1).total: 2 nodes are free of tumor (0 2).
MR1815552,left breast lump.,left breast biopsy.,received 5 grey white linear core measure 0.3 to 0.8cm. entire tissue processed.,section shows of breast tissue harboring an invasive neoplasm in nests and tubules. the neoplastic cells show moderate cytoplasm pleomorphic nuclei with moderate hyperchromasia stroma is hyalinized and desmoplastic.,left breast biopsy :invasive carcinoma nst. grade ii.modified bloom richardson score is 7 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 3 7 9
MR1815554,case of left breast lump.,left breast lump.,received 5 grey white linear core measures 0.5 to 0.8cm. entire tissue processed.,the section shows linear cores of breast parenchyma showing infiltration by tumor arranged in tubules and nests the tumor cells are round to polygonal with increased n:c ratio ovoid pleomorphic nuclear nuclei prominent nucleoli and moderate amount of eosinophilic to vacuolated cytoplasm. intervening stroma is desmoplastic.,features suggestive of invasive carcinoma nst grade ii. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1815564,left breast mass.,left breast mass biopsy.,received 7 grey white linear core measures 0.3 to 1cm. entire tissue processed.,section shows cores of breast tissue harboring an cords nests and singly scattered invasive neoplasm composed highly pleomorphic cells with abundant eosinophilic cytoplasm marked pleomorphic nuclei and increased mitosis. adjacent breast shows lymphocytic mastitis.,left breast mass biopsy :invasive carcinoma nst.grade iii. modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1815573,right breast mass.,right breast mass biopsy.,received 4 grey white linear core measures 0.5 to 1cm. entire tissue processed.,sections shows breast tissue harboring an invasive neoplasm in cords and greats composed of atypical ductal cells with increased n:c ratio moderate nuclear pleomorphism and increased mitosis. foci of high grade ductal carcinoma in situ present lymphovascular invasion seen.,right breast lump biopsy :invasive carcinoma nst. grade iii.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR1815590,case of left breast carcinoma,a) hot nodeb) blue +hot nodec) non blue non hot noded) left mastectomy.,a) received single fibrofatty tissue measures 1x0.9x0.5cmb) received single fibrofatty tissue measures 10.6x1.2x1cmc) received single fibrofatty tissue measures 1.7x1.2x1cm lymph node measures 0.5x0.3x0.2cm.d) received in : formalin procedure : mastectomy laterality : lefttotal dimensions : medial to lateral :17cm superficial to deep :5cm superior to inferior : 16cmskin ellipse :16x12cmnipple : normal scar surgical defect : not identifiedtumor : single tumor size : 4.5x3x2cm location of tumor : upper central margins of tumor : ill defined deep margin : 2.5cmmuscle : present measures 2x1x0.5adjacent breast : fibrofatty tissue axillary tail : absentsentinel lymph nodes,tumor bed : the section from the tumor shows pleomorphic cells with hyperchromatic nucleus with scanty cytoplasm,a) hot node 2 nodes isolated. no tumor deposits seen.b) blue node +hot node 1 node isolated. no tumor deposits seen.c) non blue non hot node 1 node isolated. no tumor deposits seen.total no of sentinel nodes 4 nodes. no tumor deposits seen. d) left mastectomy:histological type: invasive ductal carcinoma with focal areas of ductal carcinoma in situ comedonecrosis present.tumor measures 4.5cm.grade : iiinvasive component measures is 4cm.ductal carcinoma in situ is 0.5cm.location of tumor upper central quadrant.modified bloom richardson score is 7 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2ductal carcinoma in situ present solid and comedonecrosis measures 0.5cmlymphovascular invasion not identified.perineural invasion not identified posterior resection margin is free of tumor.nipple and areola is unremarkable.pathological stage: pt2n0summary:left mastectomy invasive ductal carcinoma grade ii.nodal metastasis sentinel nodes 4 lymph nodes no deposit of tumor.
MR1815601,left breast lump.,left breast lump biopsy.,received 4 grey white linear core measures 0.8 to 1cm. entire tissue processed.,section studied shows invasive neoplasm in extensive desmoplastic stroma. the cells are arranged in trabecular cords nests. the cells are round with scant eosinophilic cytoplasm round hyperchromatic nucleus. intranuclear inclusions are seen. stroma shows hyalinisation elastosis mild inflammatory infiltrates. area of necrosis seen.,left breast lump biopsy :invasive carcinoma nst.grade ii. modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1815613,carcinoma right breast.,right breast right modified radical mastectomy.,received in : formalin.procedure : modified radical mastectomy . laterality : right.total dimensions : medial to lateral :9cm. superficial to deep :2.5cm. superior to inferior :4cm.skin ellipse : 8x2.5cm . nipple : normal cut surface shows grey white nodule measures 1.5x1.5x1.5cm( tumor). scar surgical defect : absent.tumor : single.tumour size : 1.5 x 1.5 x 1.5 ( nipple areola). location of tumor : sub areolar.margin of tumor : ill defined. deep margin : 0.1cm.muscle : absent axillary tail :12x7x2cm.representative sections are submitted.,section studied show tumor cells arranged in glandular pattern trabecular nests and lobules separated by fibrous septa. the lesional cells have high n c ratio round vesicular nucleus prominent nucleoli and moderate amount of cytoplasm. mitotic figures are 8 10 10 hpf. lymphovascular and perineural invasion are identified. microcalcification seen.,right breast right modified radical mastectomy:invasive ductal carcinoma grade 2. tumor is located in the sub areolar region. tumor measures maximum dimension 1.5 cm. modified bloom richardson score is 7(3+2+2). ductal carcinoma in situ is not identified. lymphovascular invasion is is identified. perineural invasion is identified. posterior resection margin is free of tumor and is 0.1 cm away from the tumor. nipple and areola shows tumor reaching upto the dermis however no skin ulceration is seen.lymph nodes: five out of eighteen lymph nodes shows metastatic tumor deposit with extranodal extension(5 18). size of the largest tumor of deposit measures 0.5 cm in the greatest dimension.pathological stage: pt1cn2a
MR1815633,left breast lump.,left breast lump biopsy.,received 4 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of tumor tissue arranged in sheets trabecular cords and vague glandular pattern. the lesional cells are round to ovoid with scant eosinophilic cytoplasm round hyperchromatic nucleus moderate nuclear pleomorphism is seen. stroma is desmoplastic and shows many thick walled hyalinised blood vessels.,left breast lump biopsy :invasive carcinoma nst.grade ii.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1815639,right breast lump.,right breast lump biopsy.,received 5 grey white linear core measures 0.5 to 1.5cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in cords and nests. the neoplastic ductal cells show moderate cytoplasm increased n:c ratio hyperchromatic nuclei and increased mitoses. areas of necrosis present.tumor infiltrate into the fat.,right breast lump biopsy. :invasive carcinoma nst.grade iii. modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR1815642,right breast lump.,right breast lump biopsy.,received 5 grey white linear core measures 0.8 to 1.3cm. entire tissue processed.,section studied show linear cores of fibroadipose tissue harboring an invasive neoplasm arranged in nests trabecular glandular pattern. the lesional cells are round to polygonal with moderate eosinophilic cytoplasm moderately pleomorphic hyperchromatic nucleus. few cells are showing intranuclear inclusions. stroma is desmoplastic and shows congested blood vessels and lymphoplasmacytic infiltrates.,right breast lump biopsy :invasive carcinoma ductal origin nst.grade ii. modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1815650,carcinoma left breast post lumpectomy,left modified radical mastectomy,received in : formalinprocedure : modified radical mastectomy post lumpectomy laterality : left total dimensions : medial to lateral :22cm superficial to deep :6cm superior to inferior :20cmskin ellipse : 15x7cm nipple : unremarkable scar surgical defect : noted healed scar 7cm is seen 2cm above nipple areola.tumor : no tumor seen. lumpectomy bed noted in upper inner quadrant measures 2.5x2.5x1.5cm deep margin : 1cmmuscle : not seen axillary tail : 4x4x3cm size of largest node : 1.2x1x1cm cut surface unremarkable.,section studied show breast parenchyma with ducts of varying size stroma shows areas of hyalinisation lymphomononuclear infiltrate and multinucleated giant cells. no evidence of atypia malignancy in the material submitted.,left modified radical mastectomy.histological type:no residual tumor seenductal carcinoma in situ is not seenlymphovascular invasion is not seenperineural invasion is not seenposterior resection margin is free of tumornipple and areola is unremarkablelymph nodes:20 lymph nodes metastasis: 0(0 20) . pathological stage: yptxn0 summary: no residual tumor seen left post lumpectomylymphnode status:0 20.
MR1815723,right breast mass.,right breast mass trucut biopsy.,received 4 grey white linear core measures 0.5 to 1.2cm. entire tissue processed.,section studied from linear core of lesional tissue harbors an invasive neoplasm composed of tumor cells arranged in sheets tubules and trabecular pattern. the cells are mildly pleomorphic with hyperchromatic nuclei and inconspicuous nucleoli with scant eosinophilic cytoplasm. occasional atypical mitosis and comedo necrosis seen. stroma shows desmoplasia.,right breast mass trucut biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1815744,right breast mass carcinoma breast.,right breast mass trucut biopsy.,received 3 grey white linear core measures 1 to 1.5cm. entire tissue processed.,sections studied from linear cores of breast tissue harbors invasive neoplasm arranged in sheets tubules and trabecular pattern. the cells are large have hyperchromatic nuclei and moderate amount of cytoplasm. atypical mitosis seen. stroma shows desmoplasia with lymphoplasmacytic infiltrates.,right breast mass trucut biopsy :invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+2+3).
MR1815760,carcinoma right breast.,a) hot node.b) blue+hot node.c) right mastectomy.d) revised posterior resected margin.,a) received fibrofatty tissue measures 1.6x1.6x0.5cm. isolated one lymph node measures 0.9x0.3x0.3cm. b) received single lymph node measures 0.6x0.4x0.3cm. entire tissue processed.c) received in : formalinprocedure : right mastectomy.laterality : righttotal dimensions : medial to lateral 13.5cm superficial to deep 3.5cm superior to inferior 10cmskin ellipse : 11x6cm. nipple : normal absent tumor : singletumour size : 2.5x1.8x1cm. location of tumor : central quadrant.margins of tumor : illdefined. deep margin : 1cm.muscle : absent adjacent breast : fibrofatty tissue. axillary tail : absent.d) received single fibrous tissue measures 1.5x1x1cm. entire tissue processed.,right sentinel lymph node:a) sections from hot node show 2 lymph node free of tumor.b) sections from blue + hot node shows 3 lymph node free of tumor.c) sections shows breast parenchyma harboring an invasive tumor. the tumor shows sheets nests and cribriform pattern. the tumor cells are polygonal to columnar with enlarged vesicular nucleus prominent nucleus and moderate cytoplasm. there is moderate pleomorphism and sparse mitosis. foci of atypical ductal hyperplasia and low grade cribriform in situ carcinoma are present. there is no evidence of lymphovascular invasion perineural invasion. stroma shows hyalinisation and desmoplasia. section from deep margin are free of tumor.d) sections from revised deep margin are free of tumor.,right sentinel lymph node biopsy.a) hot node:all 2 lymph nodes received are free of tumor (0 2).b) blue+hot node:all 3 lymph node submitted are free of tumor (0 3).c) right mastectomy:histological type:invasive ductal carcinoma (nst).grade: 1tumor measures maximum dimension 2.5cmmodified br score is 5 9tubule formation: 2nuclear pleomorphism: 2mitotic figures: 1ductal carcinoma in situ presentlymphovascular invasion not identified.perineural invasion not identified.posterior resection margin is free of tumor.nipple and areola is absent.lymph nodes: 5 lymph nodes metastasis: 0 (0 5)pathological stage: pt2n0summary:right breast mastectomy invasive ductal carcinoma (nst).tumor grade: 1lymphnode status: 0 5 (hot node 0 2 blue + hot node 0 3).d) revised posterior resected margin:free of tumor.
MR1815768,case of left breast lump.,left breast lump biopsy.,received 4 grey white linear core measures 0.3 to 0.5cm. entire tissue processed.,section studied linear cores of breast parenchyma harboring invasive neoplasm arranged in glandular trabecular nests. the lesional cells are round with moderate eosinophilic cytoplasm round moderately pleomorphic hyperchromatic nucleus. few cells are showing prominent nucleoli and intranuclear inclusion periductal hyalinisation is seen. stroma is desmoplastic and shows myxoid changes. stroma shows lymphoplasmacytic infiltrates.,left breast lump biopsy :invasive carcinoma ductal origin nst. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1815782,right breast mass.,biopsy from right breast.,received 3 grey white to grey brown linear cores measures 1.0 to 1.2cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring a neoplasm arranged predominantly in glandular pattern small nests lobules separated by desmoplastic stroma. the lesional cells are round to polygonal with moderate cytoplasm round nucleus prominent nucleoli. intranuclear inclusions are seen in some stroma shows lymphoplasmacytic infiltration.,right breast mass :invasive carcinoma ductal origin nst.grade i.modified bloom richardson score is 5 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9
MR1815841,left breast mass.,left breast mass biopsy.,received 3 grey white linear core measures 0.4 to 1.2cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm composed of sheets nests poorly formed tubules and discretely scattered pleomorphic cells with abundant cytoplasm pleomorphic hyperchromatic nuclei.,left breast mass biopsy. :invasive carcinoma nst. grade 3.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1815846,case of left breast lump.,biopsy from left breast lump.,received 3 grey brown to grey white linear core measures 0.5 to 1cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring an invasive neoplasm arranged in glandular patter trabecular and small nests. the lesional cells are large polygonal with increase n:c ratio moderate to abundant eosinophilic cytoplasm markedly pleomorphic hyperchromatic nucleus prominent nucleoli. many cells are showing intra nuclear inclusions. stroma is desmoplastic.,left breast lump biopsy invasive carcinoma ductal origin nst.grade iii.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1815859,right breast mass.,right breast mass biopsy.,received 4 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring an invasive neoplasm arranged in glandular pattern trabecular cords and nests. the lesional cells are round with moderate eosinophilic cytoplasm moderately pleomorphic hyperchromatic nucleus. some showing prominent nucleoli and intranuclear inclusions. stroma is desmoplastic and shows lymphoplasmacytic infiltrates. areas of necrosis and hemorrhage seen. myxoid areas noted.,right breast mass biopsy :invasive carcinoma ductal origin nst. grade 2. modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1815905,right breast lump.,right beast lump.,received 4 grey white to grey brown linear core measures 0.6 to 1cm. entire tissue processed.,section studied shows linear cores of tumor tissue arranged in sheets nests vague glandular pattern the cells are round with scant eosinophilic cytoplasm moderately pleomorphic hyperchromatic nucleus. some showing prominent nucleoli and intra nuclear inclusions. stroma shows extensive desmoplasia and minimal inflammatory infiltrates. areas of necrosis noted.,right breast lump :invasive carcinoma nstgrade iii.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1815941,known case of carcinoma left breast.,right breast mass.,received 3 grey white linear core measures 0.8 to 1.2cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring an invasive neoplasm arranged in papillary pattern. vague glandular pattern nests trabecular. the lesional cells are round with moderate eosinophilic cytoplasm round to oval hyperchromatic nucleus some showing intranuclear inclusion. also seen area of squamoid differentiation. occasional mitotic figures seen. stroma is desmoplastic and shows thin walled blood vessels inflammatory cells composed of lymphocytes and plasma cells.,right breast mass biopsy :invasive carcinoma nst.
MR1815969,left breast lump.,left breast lump biopsy.,received multiple grey white linear core measures 0.3 to 0.5cm. entire tissue processed.,section show multiple fragments of fibrofatty tissue harboring an infiltrative lesion with cells having scant eosinophilic cytoplasm pleomorphic round to oval hyperchromatic nuclei with inconspicuous nucleoli. surrounding stroma shows desmoplasia with lymphomononuclear infiltrate.,left breast lump biopsy :invasive carcinoma nst grade 2modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1815995,right breast lump.,a) right breast wide excision.b) right axillary lymph node.,a) received wide excision measures 8x6x5cm. skin ellipse measures 6x3cm.cut surface shows grey white to grey brown hemorrhagic lesion measures 3.5x3x2cm with grey white area measuring 1cm distance from the margins:superior margin 2cm.inferior margin 2cm.medial margin 2cm.lateral margin 3cm.deep margin 2.5cm.b) received fibrofatty tissue measures 5x4x2cm.largest lymph node measures 2x1x1cm. cut surface shows fatty infiltration.,a) tumor bed:focus of residual tumor present.invasive ductal carcinoma.modified bloom richardson score is 7 9.nuclear grade ii.tubular formation 3.nuclear pleomorphism 2mitotic activity 2.surrounding the tumor there are areas of necrosis and dense inflammatory cellular infiltration consisting of lymphocytes plasma cells and giant cells.lymphovascular invasion not identified.perineural invasion is not identified.all resected margins are free from the tumor.b) 14 node no deposit of tumor.,a) right breast wide excision:residual tumor present.invasive ductal carcinoma.nuclear grade ii.maximum dimension of tumor is 1x1x0.8cm (microscopic).ductal carcinoma insitu not present.lymphovascular invasion is not present.perineural invasion is not present.all resected margins are free of tumor.b) right axillary lymph node:14 node no metastatic deposit of tumor.
MR1816002,a) left breast lump12 o clock. b) left breast lump. (3 0 clock) carcinoma breast.,a) biopsy from left breast lump 12 o clock.b) biopsy from left breast lump 3 o clock.,a) received 5 grey brown to grey white linear core measures 0.6 to 1cm entire tissue processed. b) received 4 grey white linear core measures 0.2 to 0.8cm entire tissue processed.,a) sections studied from breast parenchyma harbors invasive carcinoma forming tubules cords and isolated tumor cells in a mucinous background. the cells have scant eosinophilic cytoplasm with hyperchromatic pleomorphic nuclei. occasional atypical mitosis seen. stroma shows desmoplasia with scant inflammatory infiltrates. b) sections studied from lesional tissue composed tumor cells arranged in sheets tubules and cords. the cells are mildly pleomorphic with hyperchromatic nuclei and scant eosinophilic cytoplasm. occasional atypical mitosis seen. stroma shows dense desmoplasia.,a) left breast lump 12 o clock biopsy :mucinous carcinoma grade 2 modified bloom richardson score is 6(2+2+2).b) left breast lump 3 o clock biopsy :invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1816020,left breast lump.,biopsy from left breast lump.,received 4 grey white linear core measures 1 to 1.2cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an invasive neoplasm arranged is glandular pattern nests and trabecular. the lesional cells are round to polygonal with moderate eosinophilic cytoplasm moderately pleomorphic hyperchromatic nucleus. some showing prominent nucleoli and intranuclear inclusions. stroma is desmoplastic and shows mild inflammatory infiltrates. areas of necrosis noted.,left breast lump biopsy :invasive carcinoma ductal origin nst. grade ii.modified bloom richardson score is 7 9tubule formation : 2nuclear pleomorphism : 3mitotic figures : 2 7 9
MR1816044,carcinoma right breast nact,a)right modified radical mastectomy.b)level 3 nodes.,a)received in : formalinprocedure : modified radical mastectomy laterality : right total dimensions :medial to lateral :23cm superficial to deep :5cm superior to inferior:14cmskin ellipse : 15x8cm nipple : unremarkable scar surgical defect :absenttumour size : no tumor identified few irregular species of calcification noted deep margin :2cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail :11cmsize of largest node :1.5x1x1cmb) received single fibrofatty tissue measures 3.6x2.5x1cmisolated 1 lymph nodes measures 0.5x0.5x0.3cm.,section studied from breast parenchyma composed of comedo ductal carcinoma in situ and focal atypical ductal hyperplasia usual ductal hyperplasia. foci of fibroadenoma seen. no residual invasive carcinoma. stroma shows sclerosis with cholesterol clefts axillary lymph node shows pericapsular tumor deposit,right modified radical mastectomy:histological type:focal ductal carcinoma in situ(comedo) ductal carcinoma in situ grade 3ductal carcinoma in situ measures 0.3cm.nipple and areola is unremarkable.lymph nodes :axillary lymph node isolated 10 nodes metastasis 1(1 10).extranodal extension absent.level 3 nodes : isolated 6 nodes metastasis 0 (0 6). summary: focal ductal carcinoma situ right modified radical mastectomy.axillary lymph node isolated 10 nodes metastasis 1(1 10)extracapsular extension absent.level 3 nodes : isolated 6 nodes metastasis 0 (0 6).
MR1816073,case of right breast lump,biopsy from right breast lump.,received multiple grey white linear cores measures 0.4 to 0.6cm. entire tissue processed.,section shows linear cores of fibroadipose tissue harboring invasive tumor composed of nests and cords of pleomorphic cells with high n:c ratio and scant to moderate cytoplasm. mitosis are 1 2 hpf. stroma shows desmoplasia.,right breast lump biopsy :invasive carcinoma of ductal origin. modified bloom richardson score is 8 9grade iii. tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR1816111,left breast.,a) left breast core biopsy.b) left breast near nipple core biopsy.,a) received multiple grey white to grey brown linear cores measures 0.5 to 1.5 cm. entire tissue processed.b) received multiple grey white linear core measures 0.5 to 1cm. entire tissue processed.,section from both biopsies shows tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,a) left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).b) left breast near nipple core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1816136,right breast mass.carcinoma breast.,biopsy from right breast mass.,received 3 grey white linear core measures 0.3 to 0.5cm. entire tissue processed.,sections studied from lesional tissue harbors tumor cells arranged in single file nests and isolated tumor cells. cells are arranged concentrically around the duct. the cells have mildly pleomorphic hyperchromatic nuclei with scant cytoplasm. stroma shows desmoplasia.,biopsy from right breast mass:invasive carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1816145,case of right breast carcinoma,a) right breast carcinoma.b) revised base.c)blue +hot noded)non blue non hot node,a) received skin covered mass measures 7.5x7x4.5cmcut surface shows grey white nodular lesion measures 1.8x1.5x1.5cm.distance from margins:superior margin : 1.5cminferior margin : 2.5cmmedial margin : 0.6cmlateral margin : 3.3cmdeep margin : 1.2cmb) received fibrofatty tissue measures 1.7x1.7x0.5cm.c) received fibrofatty tissue measures 1x0.7x0.5cmlargest lymph node measures 1x0.5x0.5cmd) received fibrofatty tissue measures 2x1x0.5cm.lymph node measures 1x0.5cm.,tumor is composed of pleomorphic cells with hyperchromatic nucleus and eosinophilic cytoplasm. tubular formation less than 10 3.mitotic figures 2anaplasia 2modified bloom richardson score 7 9nuclear grade iifocal areas of ductal carcinoma in situ present. cribriform and comedonecrosis measure 0.5cm.lymphovascular invasion present.perineural invasion not identified.resected margins :superior margin:free of tumor.inferior margin:free of tumor.medial margin:free of tumor.lateral margin:free of tumor.deep margin :free of tumor.sentinel lymph nodes:2 nodes show metastatic deposit of tumor out of 3 node in paraffin section (2 3).perinodal spread not present.,right breast wide excision:maximum dimension of tumor measures 1.8x1.1cm.invasive ductal carcinoma measures 1.3cm.nuclear grade iiductal carcinoma in situ cruciform and comedonecrosis measure 0.5cm.lymphovascular invasion present.all resected margin are free of tumor.sentinel lymph nodes:2 nodes show metastatic deposit of tumor out of 3 nodes (2 3).perinodal spread not present.
MR1816177,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple core measures 1 to 1.5cm. entire tissue processed.,sections studied from linear cores of breast parenchyma harbors tumor cells arranged in sheets and nests. the cells are pleomorphic with scant cytoplasm hyperchromatic nuclei and prominent eosinophilic nucleoli atypical mitosis seen. stroma shows dense desmoplasia.,biopsy from left breast lump:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1816179,left breast lump carcinoma breast.,left breast lump,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section reveal breast parenchyma harboring lesion composed of epithelial and stromal component. the lesion shows glands and cleft like spaces lined by bilayered epithelium. foci of ductal hyperplasia is seen. hypocellular myxoid stroma with spindle to stellate cells is seen surrounding and also compressing the ducts. there is no evidence of malignancy in the sections studied.,left breast lump.benign fibroepithelial lesion.the possibilities considered are 1) fibroedenoma.2) benign phyllodes.
MR1816180,right breast mass.,biopsy from right breast mass.,received 6 grey white linear cores measures 0.8 to 1.3cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in tubules and trabecular. the cells are oval have pleomorphic hyperchromatic nuclei with inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. mitotic activity is 2 3 10hpf. ductal carcinoma in situ component is seen. stroma shows desmoplasia.,biopsy from right breast mass. :invasive carcinoma nst grade 1 with extensive ductal carcinoma in situ. modified br score is 5 9.tubular formation : 2nuclear pleomorphism : 2mitotic figures : 1 ...... 5 9 ......ductal carcinoma in situ cribriform and comedonecrosis is seen.
MR1816182,carcinoma breast post lumpectomy post chemo.,a) right breast lumpectomy post chemotherapy wide excision.b) right axillary nodes,a) received wide local excision measures 12x4.5x2.5cmskin flap measure 11.5x4.3cmlinear scar measures 7cmcut surface areas of fibrosis measures 4x2.5x2.5cmdistance from margins :superior margins :0.5cminferior margin :0.5cmmedial margin :0.5cmlateral margin :4cmdeep margin :0.1cmb) received fibrofatty tissue measures 5x3x2cmlargest lymph node measures 1x0.8x0.5cmcut surface deposits seen,sections from the fibrotic areas show extensive hyalinization atrophic lobules with ducts showing cystic change. no evidence of residual viable tumor in the sections examined.,a) right breast lumpectomy post chemotherapy wide excision:no residual viable tumor noted.chemotherapy related changes seen.no residual viable ductal carcinoma in situ.no lymphovascular invasion.no perineural invasion.resected margins are uninvolved.scar is unremarkable.b) right axillary nodes:16 lymph nodes isolated are free of tumor (0 16).
MR1816196,carcinoma left breast,biopsy from left breast.,received 4 grey white linear cores measures 0.5 0.2 cm . entire tissue processed.,section reveal linear cores of breast parenchyma harboring in situ and invasive tumor. the in situ component show solid cribriform and comedo pattern. invasive component shows tubules nests and cords composed of round to oval cells with hyperchromatic pleomorphic nucleus and scant cytoplasm. stroma shows desmoplasia.,biopsy from left breast:invasive ductal carcinoma with ductal carcinoma in situ.modified bloom richardson score is 7 9(2+3+2) grade 2
MR1816204,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear core measures 1 to 1.5cm. entire tissue pressed.,section reveal linear cores of tumor composed of acini and nests. the tumor cells are cuboidal to polygonal with high n:c ratio pleomorphic hyperchromatic nucleus prominent nucleus and moderate eosinophilic cytoplasm. intervening stroma shows desmoplasia and lymphomononuclear infiltrate.,right breast lump biopsy :invasive carcinoma of ductal origin. grade ii. modified bloom richardson score is 7 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 3 7 9
MR1816215,suspected case of vertebral metastasis for evaluation carcinoma breast.,biopsy from left breast lump,received 4 grey white linear cores measures 0.8 1.5cm. entire tissue processed.,section reveal linear cores of fibroadipose tissue with tumor infiltrating in the form of sheets and cords of round to oval cells high n c ratio hyperchromatic nucleus and scant cytoplasm. atypical mitotic figures are seen.,biopsy from left breast lump:invasive carcinoma with lobular features.nuclear grade ii.
MR1816216,left breast mass carcinoma breast.,left breast core biopsy.,received 3 linear cores measures 1.5 to 2cm. entire tissue processed.,section shows tumor cells in sheets nests cords and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1816230,right breast lump carcinoma breast.,biopsy from right breast.,received multiple grey white core measures 1.7 to 1.8cm. entire tissue processed.,sections studied from linear cores of breast parenchyma harbors on invasive neoplasm composed of tumor cells arranged in tubules nests and in solid sheets. the cells are mildly pleomorphic with scant cytoplasm and hyperchromatic nuclei. occasional atypical mitosis seen stroma shows mucin with desmoplastic reaction.,biopsy from right breast:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1816235,carcinoma left breast.,a) left breast wide local excision.b) sentinel lymphnode biopsy blue hot nodes. c) sentinel lymphnode biopsy hot nodes. d) revised medial margin.,a) left breast wide local excision. lumpectomy specimen measures 9x5x4.5cm. on cut open single grey white to grey brown ill difined tumor measures 2.2x2x1.5cm adjacent breast shows desmoplastic reaction skin ellipse measures 5.4x1.6cm. distance from margins :anterior margin : 1.8 cm.medial margin : 1.4 cm.superior margin : 2.5 cm.lateral margin : 3.5 cm.deep margin : 2.6 cm.b) sentinel lymphnode biopsy blue hot nodes. received fibrofatty tissue measures 2.8 x2.5x0.9cm. isolated three lymphnode. largest measures 2.5x0.8x0.7cm. cut surface fatty infiltrated. entire tissue processed.c) sentinel lymphnode biopsy hot nodes. received fibrofatty tissue measures 1.3x0.7x0.3cm. isolated two lymphnode largest measures 0.7x0.6x0.4cm. cut surface fatty infiltrated. entire tissue processed. d) specimen of revised medial margin (thread away from lesion). received fibrofatty tissue measures 5.5x4x0.7cm with one surface inked. received fibrofatty tissue measures 4.5x3x1.5cm. no lesion identified.,section studied show breast parenchyma harboring an infiltrating lesion arranged in nests and sheets. the cells are ovoid having moderate amount of eosinophilic cytoplasm vesicular nuclei prominent nuclei some cells have multiple nucleoli. mitotic figures are discerned. stroma is desmoplastic with mild lymphomononuclear cells infiltration. area of hemorrhage and extravasted mucin pools also noted.,a) left breast wide local excision. invasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 2nuclear pleomorphism : 3mitotic figures : 2 7 9 .........tumor measures 2.2cm in greatest dimension.depth of tumor 1.5 cm in greatest dimension. lymphovascular invasion and perineural invasion not seen. ductal carcinoma in situ seen. all margins of resections (superior interior lateral deep). margin are free of tumor.medial margin ductal hyperplasia.b) sentinel lymphnode biopsy blue hot nodes. isolated 3 lymphnodes free of tumor (0 3).c) sentinel lymphnode biopsy hot nodes. isolated 2 lymph nodes are free of tumor (0 2)d) revised medial margin shows ductal hyperplasia.
MR1816279,right breast mass. carcinoma breast.,right breast mass.,received multiple grey white linear cores measures 0.5 to 1cm. entire tissue processed.,sections studied from linear cores of breast parenchyma harbors tumor cells arranged in sheets and nests. the cells are pleomorphic with scant eosinophilic cytoplasm and hyperchromatic nuclei. stroma shows osteoid matrix with focal calcification and mucin.,right breast mass core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1816288,right breast lump carcinoma breast.,biopsy from right breast lump.,received multiple grey white linear cores measures 0.3 to 1cm. entire tissue processed.,section studied shows linear cores of breast parenchyma with extensive areas of desmoplasia. harboring an infiltrating lesion arranged in tubules and focal nests. the cells are oval having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. stroma shows extensive areas of desmoplasia. ductal carcinoma in situ with comedonecrosis is seen.,right breast biopsy :invasive carcinoma nst grade 1. modified bloom richardson score is 5 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9 ductal carcinoma in situ comedonecrosis is seen.
MR1816291,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 1.8 to 2cm. entire tissue processed.,sections studied from linear cores of breast parenchyma harbors tumor cells arranged in sheets and nest. the cells are pleomorphic with scant cytoplasm and hyperchromatic nuclei and occasional cells shows prominent nucleoli. occasional atypical mitosis seen. stroma shows desmoplasia with lymphomononuclear infiltrate.,biopsy from left breast lump:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1816318,right breast lump.,biopsy from right breast lump.,received 4 grey white linear cores measures 0.8 to 1.5cm. entire tissue processed.,sections studied from linear cores of breast parenchyma shows ductal epithelial cells arranged in solid and cribriform pattern showing mild pleomorphic nuclei and moderate amount of eosinophilic cytoplasm. few showing eccentrically placed nuclei. no invasion of ductal cells into the stroma seen. stroma shows desmoplasia.,right breast lump biopsy :suggestive of atypical ductal hyperplasia with foci suspicious of ductal carcinoma in situ. suggest myoepithelial panel for further confirmation of ductal carcinoma in situ.
MR1816320,left breast mass.carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear core measures 0.5 to 1.2cm. entire tissue processed.,sections studied from linear cores of breast parenchyma harbors tumor cells arranged in sheets. the cells are highly pleomorphic with scant cytoplasm hyperchromatic nuclei. stroma shows dense lymphocytic response.,biopsy from left breast lump:invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+3+2).
MR1816344,left breast lump carcinoma breast.,biopsy from left breast.,received 4 linear cores each measures 1.0 to 1.5cm. entire tissue processed.,section shows tumor cells in sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular invasion is seen. perineural invasion is not seen.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). lymphovascular invasion is seen. perineural invasion is not seen. ductal carcinoma in situ of solid pattern with intermediate nuclear grade.
MR1816345,left breast lump carcinoma breast.,left breast lump core biopsy.,received 4 linear cores grey white tissue measures 0.5 to 2cm. entire tissue processed.,section shows cores of fibrocollagenous tissue infiltrated by tumor cells in sheets and lying singly. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1816359,right breast mass.,biopsy from right breast lesion.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm composed of nests cords and tubules. the neoplastic cells display abundant cytoplasm highly pleomorphic nuclei showing hyperchromasia. stroma is desmoplastic.,biopsy from right breast lesion. :invasive carcinoma nst. grade iii.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1816391,right breast lump.,biopsy from right breast lump.,received 4 grey white linear cores each measures 0.5 to 1.0cm . entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1816417,carcinoma right breast.,a) sentinel lymph node biopsy.b) right breast wide local excisionc) revised inferior margin.,a) received fibrofatty measures 2x2x1cm isolated 3 lymph nodes.largest one measures 1.2x1x1cmb) received lumpectomy specimen measures 8.8x6.5x5cmskin ellipse measures 5.8x2cm surface of skin shows stitches.cut surface tumor identified measures 3x2.5x2.5cmcut surface tumor shows grey white grey yellow granular areas margins irregular distance from the margin:superior margin 1.8cminferior margins 1.8cmlateral margins 2.3cmmedial margin 2.2cmdeep margin 0.8cmc) received fibrofatty tissue measures 6.5x3.5x3cm,b) section studied show breast parenchyma harboring an infiltrating lesion arranged in nests islands and sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned . stroma is desmoplastic with areas hemorrhage and necrosis.,a) sentinel lymph node biopsy:isolated three lymph nodes are free of tumorb) right breast wide local excision:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic activity : 2 7 9 tumor measure 3.0cminvasive carcinoma measure 2.7cmductal carcinoma in situ measure 0.3cmductal carcinoma in situ solid pattern is seenlymphovascular invasion and perineural invasion are not seenall margins ( superior inferior mediate lateral and deep margins) are free of tumor.c) revised inferior margin:free of tumorpathological stage : pt2no
MR1816428,left breast mass.,biopsy from left breast.,received 4 grey white linear cores 1.0 x 1.5cm. entire tissue processed.,section show multiple cores of breast parenchyma harboring infiltrating lesion arranged in tubules cords and sheets. the cells are having hyperchromatic nuclei moderate cytoplasm. the cells exhibit mitosis 5 6 10hpf. stroma shows desmoplasia and lymphocytic infiltrate.,left breast mass biopsy :invasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 2nuclear pleomorphism : 3mitotic figures : 2 7 9 ductal carcinoma in situ (cribriform and solid type)
MR1816440,left breast mass.,biopsy from left breast.,received 6 linear cores measures 1.5 to 2cm. entire tissue processed.,section studied shows breast parenchyma harboring an infiltrating lesion arranged in nests and islands. the cells are ovoid having moderate amount of cytoplasm. hyperchromatic nucleus and prominent nucleoli in few. occasional mitotic figures are discerned. stroma is desmoplastic with mild lymphomononuclear cell infiltrate. areas of hemorrhage and necrosis is seen.,left breast biopsy invasive carcinoma nst grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1816464,right breast mass carcinoma breast.,biopsy from right breast mass.,received 6 linear cores measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an invasive tumor. the tumor shows nests trabeculae and cords of polygonal cells with high n c ratio hyperchromatic nucleus and scant to moderate cytoplasm. there is marked pleomorphism and brisk mitotic activity. intervening stroma shows desmoplasia and mild lymphomononuclear infiltrate.,right breast mass :invasive carcinoma (nst) of ductal origin.grade 3modified bloom richardson score is 9 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 3 9 9
MR1816499,right breast lump carcinoma breast.,biopsy from right breast lump.,received 5 grey white to grey brown linear core measures 0.5 to 1.3cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an infiltrating lesion arranged in islands and nests. the cells are large pleomorphic with moderate amount of cytoplasm hyperchromatic pleomorphic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma is desmoplastic with moderately dense lymphomononuclear infiltrates.,right breast biopsy :invasive carcinoma nst grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1816508,right breast lesion birads iv a.,biopsy from right breast lesion.,received 5 grey white linear core measures 0.5 to 1cm. entire tissue processed.,section reveal linear cores of breast parenchyma harboring tumor infiltrating in the forms of nests cords and scant cytoplasm.tumor cells show high n:c ratio hyperchromatic pleomorphic nucleus and scant cytoplasm mitosis are sparse stroma shows desmoplasia.,right breast lump biopsy :invasive carcinoma (nst) of ductal origin. grade i. modified bloom richardson score is 5 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9
MR1816509,carcinoma right breast.,right modified radical mastectomy post lumpectomy.,received in : formalinprocedure : right modified radical mastectomy post lumpectomy.laterality : right total dimensions : medial to lateral 18cm. superficial to deep 4cm. superior to inferior 11cm.skin ellipse : 13x5.5cm. nipple : peri areolar skin thickening is noted.scar surgical defect : 4cm scar in upper outer quadranttumor size : 1x1x1cm.location of tumor : upper outer quadrant below this scar.margins of tumor : illdefineddeep margin : 0.5cm.muscle : absent adjacent breast : fibrofatty tissue.axillary tail : 4x4x4cm.size of largest node : 2.5x1x1cm. cuts surface is grey white deposit.,section from breast parenchyma shows small foci of residual viable tumor along with chronic inflammatory infiltrates composed of multinucleated giant cells neutrophils eosinophils and lymphocytes.,right modified radical mastectomy post lumpectomy.histological type: small foci of residual tumor seen at the margin of post lumpectomy.tumor measures maximum dimension 0.5cmductal carcinoma in situ is not identified.lymphovascular invasion is not identified.perineural invasion is not identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes:nine out of seventeen lymph nodes show metastatic tumor deposits with extranodal extension seen(9 17).largest tumor deposit measures 2cm in greatest dimension.pathological stage: pt1n2summary:right modified radical mastectomy post lumpectomy.small foci of residual viable tumor .lymph nodes:nine out of seventeen lymph nodes show metastatic tumor deposits (9 17)extranodal extension seen.
MR1816539,left breast mass carcinoma breast.,left breast lump.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section reveals linear cores of breast parenchyma harboring invasive tumor in the form of nests cords tubules composed of round to polygonal cells with hyperchromatic nucleus and scant cytoplasm. nuclear pleomorphism is moderate and mitosis are 6to7 10hpf. large areas of necrosis are seen.,left breast lump:invasive carcinoma (nst) of ductal origin grade 2.modified bloom richardson score is (2+2+2) 6 9.areas of necrosis seen.
MR1816595,right breast lump.,biopsy from right breast lump,a) received unoriented fibrofatty tissue measures 9x7x3cm. cut surface firm ill defined grey white lesion measures 2x1.5x1.5cm. nearest margin 0.2cm. awayb) received single fibrofatty tissue measures 6x4x4cm largest measures 2.5x1x1cm. fatty infiltration seen.,a) sections shows breast parenchyma harboring foci of comedo ductal carcinoma in situ and a few solid nests with myoepithelial layer intact.no lymphovascular invasion seen. b) section shows 12 lymphnodes with are unremarkable.,a) biopsy from right breast lump. high grade ductal carcinoma in situ (comedo pattern) no lymphovascular invasion seen. no perinodal invasion seen. margin is 0.2cm. away from the lesion.b) 12 right axillary lymph nodes isolated are free of tumor.
MR1816606,carcinoma right breast post lumpectomy.,a)right breast wide local excision ( post lumpectomy).b) right sentinel lymph node( blue node)c) right sentinel lymph node ( suspicious node),a) received skin covered fibrofatty tissue measures 6x4x2cm.skin nipple areola measures 3x0.6cm.cut surface shows cystic specimen measures 1.5x1x0.5cm.distance from margins:superior margin : 1cminferior margin : 1cmmedial margin : 1.5cmlateral margin : 3.5cmdeep margin : 0.5cmb) received single lymph node measures 1x0.5x0.5cm. entire tissue processed.c) received single lymph node measures 0.5x0.5x0.5cm. entire tissue processed.,section shows features of ductal carcinoma in situ with intermediate nuclear grade. no definite evidence of invasion is seen.,a)right breast wide local excision ( post lumpectomy):ductal carcinoma in situ of solid cribriform and comedo pattern with intermediate nulcear grade. multiple foci are seen largest measuring 0.5 cm in greatest dimension. inferior margin shows foci of ductal carcinoma in situ. superior medial lateral and deep margins of resection are free of tumor. overlying skin is free of tumor.b) right sentinel lymph node( blue node):one lymph node is identified negative for malignancy(0 1).c) right sentinel lymph node ( suspicious node):one lymph node is identified negative for malignancy(0 1).
MR1816666,left breast mass carcinoma breast.,biopsy from left breast mass.,received 5 grey white to grey yellow linear core measures 0.5 to 1.2cm. entire tissue processed.,section studied shows linear cores of invasive neoplasm arranged in nests glandular pattern trabecular. the lesional cells are polygonal abundant eosinophilic cytoplasm round hyperchromatic nucleus prominent nucleoli. mitotic figures are seen occasionally stroma is desmoplastic and shows lymphoplasmacytic infiltrates and histiocytes. myxoid areas are seen. areas of necrosis noted.,biopsy from left breast mass. :invasive carcinoma nstgrade ii. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1816677,carcinoma right breast post chemo,right modified radical mastectomy.,received in : formalin.procedure : modified radical mastectomy. laterality : righttotal dimensions : medial to lateral :19cm. superficial to deep :4.5cm. superior to inferior :14cm.skin ellipse :13x9cm. nipple :normal. scar surgical defect : 3cm at 7 8 clock positiontumor : single.tumour size : 0.5x0.3x0.3cm. cut surface yellow necrotic location of tumor : lower outer quadrant. margin of tumor : illdentified . deep margin :3.5cm.muscle : absent.adjacent breast :fibrofatty tissue. axillary tail :13x7.5x2.5cm. size of largest node :2.5x2x0.5cm.,section studied from tumor shows neoplasm arranged in glandular pattern and nests. the lesional cells are round with high n c ratio moderately pleomorphic vesicular nuclear prominent nucleoli. mitotic figures are 4 6 10 hpf with occasional atypical mitotic figures. also seen are therapy related changes. extensive hyalinistion dense lymphoid aggregates foci of necrosis and foreign body giant cells reaction. deep is free of tumor,right modified radical mastectomy:(post nact)invasive carcinoma nst residual tumor present grade:2.invasive component measures 0.5cm.modified br score is7 9.tubule formation:3 . nuclear pleomorphism:2 .mitotic figures: 2.lymphovascular invasion identified.perineural invasion indeterminate . posterior resection margin is free of tumor.nipple and areola is unremarkable and free of tumor.lymph nodes: 29 lymph nodes metastasis:0(0 29). summary: residual invasive carcinoma. right breast.tumor grade:2lymph node status: isolated twenty nine lymph nodes. none show metastatic deposits of tumor (0 29).
MR1816715,left breast lump carcinoma breast.,left breast lump biopsy.,received 3 grey white linear core measures 0.8 to 1.2cm. entire tissue processed.,sections reveal linear core of breast parenchyma with tumor infiltrating in the form of nests cords and occasional acini composed of round to oval cells with high n:c ratio hyperchromatic nucleus and scant cytoplasm nuclear pleomorphism is moderate and mitosis are 6 10hpf. stroma shows marked desmoplasia and lymphomononuclear infiltrate.,left breast lump :invasive carcinoma (nst) of ductal origin nuclear grade 2. note : scanty tumor foci seen.
MR1816723,carcinoma left breast.,a) left breast lumpectomy.b) sentinel lymph node dissection.c) axillary dissection (left).,a) received skin covered fibrofatty tissue measures 14x9x6cm.skin ellipse measures 5x4cm. cut surface shows tumor measures 5x4x3cm.distance from the tumor.superior margin 2.5cm.inferior margin 4cm.medial margin 2cm.lateral margin 6cm.deep margin 1.5cm.b) received fibrofatty tissue measures 4x3x2cm. 2 lymph nodes.largest measures 4x2x1cm.c) received fibrofatty tissue measures 12x10x8cm.largest lymph node measures 2x1x1cm. cut surface is grey brown homogeneous.,section from the lesion shows a partially circumscribed neoplasm composed of syncitial sheets of pleomorphic cells with vesicular nuclei and prominent nucleoli. brisk mitosis is seen. there is moderate intratumoral lymphocytic infiltrate and peritumoral lymphoid infiltrate noted. areas of geographic necrosis seen.,a) left breast lumpectomy:invasive carcinoma with medullary features .modified bloom richardson score is 9 9 (3+3+3) grade iii.tumor measures 5cm in greatest dimension.ductal carcinoma in situ not identified.lymphovascular invasion indeterminate.perineural invasion not identified.deep margin shows tumor cells however inked margin is free of tumor.all other resected margins are free of tumor.b) sentinel lymph node dissection:2 lymph nodes isolated show tumor deposits largest measures 1.2cm.perinodal spread present.c) axillary dissection (left): 15 lymph nodes isolated are free of tumor.total 2 out of 17 nodes shows tumor deposits (2 17).pathological stage pt2n1
MR1816728,carcinoma left breast.,a) left breast wide local excision.b) left sentinel node dissection : blue + hot nodes.c) left sentinel node dissection : hot nodes.d) revised deep margin.,a) received wide local excision specimen measures 11x7x2cm. skin ellipse measures 5x2cm. cut surface shows grey white lesion measures 1x0.8x0.5cm.distance from the margins:superior margin 2.5cm.inferior margin 3cm.medial margin 2cm.lateral margin 2.2cm.b) received two nodes. largest measures 2.5x2x0.5cm. smaller measures 1x0.5x0.5cm. entire tissue processed.c) received single fibrofatty tissue measures 1x0.5x0.5cm. entire tissue processed.d) received fibrofatty tissue measures 3.5x2.5x1.5cm. one surface inked.,section from the lesion shows breast parenchyma harboring an invasive neoplasm in sheets cords and nests. the cells show moderate cytoplasm round nuclei with coarse chromatin and prominent nucleoli. there is extensive intra and peritumoral lympho plasmacytic infiltrate.,a) left breast wide local excision:invasive ductal carcinoma.modified bloom richardson score (3+2+2) 7 9 grade ii.tumor measures 1cm in greatest dimension.invasive carcinoma measures 1cm.ductal carcinoma in situ not identified.lymphovascular invasion not seen.perineural invasion not seen.resected margins are free tumor.b) left sentinel node dissection : blue + hot nodes. (frozen):2 nodes are free of tumor 0 2.c) left sentinel node dissection : hot nodes. ( frozen).1 node is free of tumor 0 1.total 3 nodes are free of tumor 0 3d) revised deep margin.free of tumor .pathological grade pt1n0.
MR1816755,left breast lesion.,biopsy from left breast lesion.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections studied from linear cores harbors tumor cells arranged in sheets and as few scattered single cells. the cells have scant eosinophilic cytoplasm pleomorphic hyperchromatic nuclei with occasional cells show prominent eosinophilic nucleoli stroma shows dense desmoplasia with scattered lymphocytes.,left breast mass core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1816758,right breast lump with ulceration.,biopsy from right breast lump.,received 3 grey white to grey brown linear cores measures 0.5 to 1.3cm. entire tissue processed.,section shows linear cores of breast parenchyma with invasive tumor. the tumor shows sheets and nests of round to oval cells with high n:c ratio hyperchromatic nucleus and scant cytoplasm. nuclear pleomorphism is marked and mitosis are 6 8 10hpf. stroma shows desmoplasia and lymphomononuclear infiltrate.,biopsy from right breast lump :invasive carcinoma (nst) of ductal origin.grade 3 modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9
MR1816761,a) right breast. b) left breast.,a) biopsy from right breast mass. b) biopsy from left breast mass.,a) received multiple grey white to grey brown soft tissue bits measures 0.3x0.2x0.1cm. entire tissue processed. b) received multiple grey white to grey brown fragmented cores measures 0.5 to 0.8cm. entire tissue processed.,sections studied from lesional tissue composed of multiple layers of tumor cells radially arranged around central fibrovascular core. the cells are mildly pleomorphic with eosinophilic cytoplasm and hyperchromatic nucleus. stroma is hyalinised with scattered lymphocytes. b) section studied from lesional tissue composed of tumor cells arranged in tubules sheets and nests. the cells have eosinophilic cytoplasm and pleomorphic hyperchromatic nucleus. extracellular mucin pools are seen around tumor cells. stroma shows desmoplasia.,a) right breast biopsy :suggestive of papillary neoplasm.suggest excision of lump for further confirmation.b) left breast biopsy suggestive of papillary neoplasm highly suspicious of invasive papillary carcinoma.need further confirmation on larger specimen.
MR1816767,left breast lump.,biopsy from left breast lump.,received multiple grey white to grey brown measures 0.5 to 0.8cm. entire tissue processed.,section reveal breast parenchyma harboring tumor infiltrating as nests and sheets composed of polygonal cells with high n:c ratio hyperchromatic nucleus and scant to moderate cytoplasm. atypical mitosis and foci of necrosis are seen. stroma shows desmoplasia and lymphomononuclear infiltrate one fragment show skin with adnexal stroma.,biopsy from left breast lump. :invasive carcinoma of ductal origin (nst).grade ii. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1816799,carcinoma right breast.,a) right breast wide excision.b) right axillary lymph nodes.,a) received wide excision of breast specimen measures 11x7x5cm. skin ellipse measures 9x2cm. unremarkable.nipple areola unremarkable.cut surface shows solid grey white tumor measures 2x1x1cm. tumor extends upto subcutaneous tissue distance from the margins.superior margin 2.5cm.inferior margin 3cm.medial margin 4cm.lateral margin 7cm.deep margin 1.5cm.b) received fibrofatty tissue measures 7x6x5cm.largest lymph node measures 2.5x2x1cm cut surface shows fatty infiltration.,a) tumor consists of pleomorphic cells with hyperchromatic nucleus with scanty cytoplasm. the cells are arranged in clumps groups ad sheets with tubular formation less than 10 (3).mitotic figures 2.nuclear pleomorphism 2.modified bloom richardson score is 6 10.nuclear grade ii.lymphovascular invasion not identified.perineural invasion not identified.all resected margins are free from tumor.b) 8 nodes no deposits of tumor.,a) right breast wide excision:invasive ductal carcinoma maximum size of the tumor is 2cm.invasive carcinoma measures 2cm.nuclear grade ii.ductal carcinoma in situ not present.lymphovascular invasion not identified.all resected margins free of tumor.b) right axillary lymph nodes:8 nodes no deposits of tumor.0 8pathological grade : pt1n0.
MR1816806,right breast lump.,biopsy from right breast lump.,received 6 grey white to grey yellow linear core measures 0.6 to 1.0cm. entire tissue processed.,section studied shows linear core of breast parenchyma showing a cystic space with epithelium showing papillary in folding and foccal glandular architecture. the papillae and glands are lined by columnar to cuboidal cells having enlarged vesicular nuclei and nuclear stratification and moderate cytoplasm. lesion shows areas of infarct . adjacent breast shows ductal carcinoma in situ.,right breast lump. features suggestive of papillary lesion with infarction and few atypical cellssuggest frozen confirmation excision biopsy.
MR1816824,left breast lump carcinoma breast.,biopsy from left breast.,received 4 grey white to grey brown linear core measures 1 to 1.2cm. entire tissue processed.,section shows linear core of breast parenchyma with tumor infiltrating in the from of nests and cords composed of round to oval cells with high n:c ratio hyperchromatic nucleus and moderate clear to eosinophilic cytoplasm. nuclear pleomorphism is moderate and mitosis are brisk stroma shows desmoplasia.,biopsy from left breast lump.invasive carcinoma (nst) of ductal origin. grade iii. modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MR1816831,carcinoma left breast.,a) left breast post lumpectomy wide excision.b) sentinel node (blue+hot node)c) sentinel node (hot node)d) axillary dissection (left).,a) received skin covered soft tissue bits measures 10x7x5cm. skin flap measures 8.5x1.6cm.cut surface shows tumor measures 4x1x1cm.distance from the margins:superior margin 1.5cm.inferior margin 2.5cm.medial margin 2.5cm.lateral margin 2.5cm.deep margin 2cm.b) single lymph node measures 2x1.5x0.5cm.c) received largest 2 lymph nodes measures 0.8x0.5x0.5cm smallest measures 0.5x0.5x0.5cm.d) received fibrofatty tissue 11x9x4cm. largest lymph node measures 1x1x1cm.,section from the fibrotic areas show extensive fibrosis histiocytic and lymphoplasmacytic infiltrates. few ducts showing ductal adenosis. no evidence of residual tumor seen.,a) left breast post lumpectomy wide excision:no residual tumor seen.no lymphovascular invasion.all resected margins are free of tumor.b) sentinel node (blue+hot node):1 node isolated shows deposits of invasive carcinoma (1 1) measures 0.4cm.no extranodal extension seen.c) sentinel node (hot node):2 nodes are free of tumor (0 2).d) axillary dissection (left):10nodes are free of tumor (0 10).pathological stage : yptxn1
MR1816860,right breast lump carcinoma breast.,right breast lump biopsy.,received 4 grey white to grey yellow linear core measures 0.5 to 1cm. entire tissue processed.,section show linear cores of breast parenchyma harboring invasive lesion in the form of nests cords and tubules composed of round to oval cells with enlarged pleomorphic hyperchromatic nucleus and moderate clear to eosinophilic cytoplasm. foci of perineural invasion is seen. stroma shows desmoplasia and calcification.,biopsy from right breast lump.invasive carcinoma (nst) of ductal origingrade 2. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 perineural invasion is seen.
MR1816871,left axillary nodes metastasis.,biopsy from left axillary node.,received 4 grey white linear cores measures 0.8 to 1 2cm. entire tissue processed.,section show linear cores of tumor composed of nests of round to oval cells floating in extracellular pools of mucin. thee cells show hyperchromatic nucleus scant to moderate cytoplasm.there is mild pleomorphism stroma shows desmoplasia and few lymphoid aggregates.,biopsy from left axillary node. :metastatic carcinoma. (mucinous component) in a known case of carcinoma left breast.
MR1816877,carcinoma left breast( post lumpectomy),a) left modified radical mastectomyb) left level 3 nodes.,a)received in : formalinprocedure : modified radical mastectomy laterality :lefttotal dimensions : medial to lateral :22cm superficial to deep :8cm superior to inferior :22cmskin ellipse : 17x10 nipple :normal scar surgical defect :identified 9cm from upper outer quadrant to lower outer quadranttumor : singletumour size :4x4x4cm location of tumor : upper outer lower outer quadrant margin of tumor : ill defined deep margin :0.4cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail :13x6x4cmsize of largest node : 3x1x0.5cm cut surface grey white fatty infiltration.b) received fibrofatty tissue measures 2.8x2x2cm. entire tissue processed.,section shows tumor infiltrating breast parenchyma in the from of sheets composed of pleomorphic round to oval cells with high n c ratio vesicular nucleus prominent nucleolus and moderate cytoplasm. mitosis 2 3 hpf and large areas of necrosis seen. the tumor is seen infiltrating the dermis . epidermis is free of tumor. focal foamy histiocytes and foreign body giant cells collection are seen.,a) left modified radical mastectomy:histological type:residual invasive ductal carcinoma nstgrade:3tumor measures maximum dimension 4cm.invasive component measures 4cm.modified br score is9 9.tubule formation:3. nuclear pleomorphism: 3.mitotic figures: 3.ductal carcinoma in situ nil.lymphovascular invasion not identified perineural invasion not identified posterior resection margin is free of tumor.nipple and areola is unremarkable tumor infiltrating dermis .epidermis is free of tumor.lymph nodes: 22 lymph nodes metastasis: 0(0 22) . b) left level 3 lymph nodes:all the 3 lymph nodes isolated are free of tumor (0 3).pathological stage: 9t2n0 summary: residual invasive ductal carcinoma nst.tumor grade:3lymph node status:0 25 ( left mrm 0 22. left level 3 lymph nodes 0 3)
MR1816884,carcinoma right breast.,a) right breast wide excision post lumpectomy.b) revised inferior margin.c) right axillary nodal tissue.,a) received wide excision specimen measures 7x4x2cm. skin ellipse measures 5.3x1.4cm. serial sections revealed no obvioius lesion. gray yellow areas measures 0.8x0.6x0.5cm noted close to the inferior margin.distance from the margin.superior margin 2.2cm.inferior margin 0.1cm.medial margin 1.5cm.lateral margin 3.5cm.deep margin 1.8cm.b) received single fibrofatty tissue measures 3x2x1cm. one surface inked.c) received fibrofatty tissue measures 11x5x1.5cm.largest measures 1x0.5x0.5cm.,sections show breast parenchyma with areas of fat necrosis hyalinisation histiocytic lymphoid aggregates and foreign body giant cells. occasional ducts with comedo type necrosis with degenerated tumor cells. no viable tumor cells seen.,a) right breast wide excision post lumpectomy:very tiny focus showing and ducts with comedo type ductal carcinoma in situ with degenerated tumor cells.no residual invasive carcinoma.no lymphovascular invasion no perineural invasion.all resected margins including deep margin are free of tumor.b) revised inferior margin:free of tumor.c) right axillary nodal tissue:14 nodes isolated are free of tumor (0 14).
MR1816886,a) right breast lump.b) left breast lump.,a) biopsy from right breast lump. b) biopsy from left breast lump.,a) received 4 grey white linear cores measures 1.0 to 1.5cm. entire tissue processed. b) received 4 grey white to grey brown linear cores measures 0.8 to 1.2cm. entire tissue processed.,a) section studied from linear cores harbors invasive neoplasm composed of tumor cells arranged in nests and vague acini. the cells have eosinophilic to clear cytoplasm and pleomorphic nuclei with prominent nucleoli occasional cells show prominent nucleoli stroma shows desmoplasia. b) section studied form linear cores of breast parenchyma harboring tumor cells are arranged in nests in the syncitial like growth pattern. the cells are cuboidal with clear eosinophilic cytoplasm and pleomorphic hyperchromatic nuclei stroma shows desmoplasia.,a) right breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2)b) left breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2)
MR1816925,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear core measures 1 to 1.3cm. entire tissue processed.,section reveal breast parenchyma harboring invasive tumor composed of small round to oval cells with high n:c ratio and scant cytoplasm arranged in cords and small nests. these cells show moderate pleomorphism and atypical mitosis. few cells show intracytoplasmic lumina. stroma shows hyalinisation desmoplasia and myxoid change.,biopsy from left breast lump. :poorly differentiated malignancy.suggestive of invasive carcinoma with lobular features.suggest ihc.
MR1816932,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white to grey brown linear core measures 1 to 1.4cm entire tissue processed.,section shows linear cores of breast parenchyma harboring tumor infiltrating in the form of nests and sheets composed of round to oval cells with high n:c ratio hyperchromatic nucleus and scant cytoplasm. storms shows desmoplasia and myxoid changed,biopsy from right breast lump. :invasive carcinoma of ductal origin. grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 1mitotic figures : 2 6 9
MR1816938,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section reveal linear cores of breast parenchyma harboring invasive tumor in the form of nests and cords of polygonal cells with pleomorphic hyperchromatic nucleus and moderate cytoplasm small foci of necrosis are seen. stroma shows marked desmoplasia.,biopsy from right breast lump :invasive carcinoma of ductal origin (nst).grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 1 7 9 foci of necrosis seen.
MR1816946,right breast lump carcinoma breast.,biopsy from right breast lump.,received 5 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section reveal linear cores of breast parenchyma harboring tumor infiltrating in the form of tubules and nests composed of polygonal cells with high n:c ratio scant to moderate eosinophilic to clear cytoplasm and moderate pleomorphism stroma shows marked desmoplasia necrotic foci are seen.,biopsy from right breast lump. :invasive carcinoma (nst) of ductal origin.grade 1modified br score is 5 9.tubular formation : 2nuclear pleomorphism : 2mitotic figures : 1 ...... 5 9 ......
MR1816949,carcinoma left breast post excision.,a) left breast wide excision post lumpectomy.b) revised lateral margin.c) hot nodes.d) hot + blue node.e) re revised lateral margins.,a) received lumpectomy specimen measures 8x6x2cm skin ellipse measures 5x1cm. serial sections reveal defect measures 2.5x2.1x1cm. adjacent areas are fibrotic measures 2x1x1cm.distance from margins.superior margin 2cm.inferior margin 3cm.medial margin 0.2cm.lateral margin 2.1cm.deep margin 3cm.b) received fibrofatty tissue one surface is inked. total measures 4x2.5x0.5cm. no lesion identified.c) received 2 lymph nodes largest measures 1x0.5x0.5cm. cut surface shows fatty infiltration.d) received 2 lymph nodes largest measures 2.1x2x0.5cm.e) received flap of fibrofatty tissue measures 4.2x3.2x0.5cm.,sections from the lumpectomy bed show ducts showing solid and cribriform type ductal carcinoma in situ (intermediate grade) and extensive areas of histiocytic aggregates granuloma and foreign body type giant cells. no residual invasive carcinoma noted.,a) left breast post lumpectomy wide excision:residual ductal carcinoma in situ solid and comedo type measures 2cm intermediate grade.no residual invasive carcinoma seen.no lymphovascular invasion or perineural invasion noted.superior inferior and medial margin is free of tumor.lateral margins shows ductal carcinoma in situ.b) revised lateral margin:shows ductal carcinoma in situ.sentinel lymph node biopsy (frozen).c) hot nodes:1 node is free of tumor 0 1.d) hot + blue node:2 nodes are free of tumor 0 2.total 3 nodes free of tumor (0 3).e) re revised lateral margin:inked margin is free of tumor.
MR1816954,right breast lump carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measures 0.8 to 1.1cm. entire tissue processed.,section shows linear cores of tumor composed of nests and cords. the tumor cells are round to oval with mild pleomorphism high n:c ratio hyperchromatic nucleus and scant cytoplasm. mitosis are sparse. stroma shows marked desmoplasia.,right breast lump.invasive carcinoma (nst) ductal origin. grade 1. modified br score is 5 9.tubular formation : 3nuclear pleomorphism : 1mitotic figures : 1 ...... 5 9 ......
MR1816956,right breast lump carcinoma breast.,biopsy from right breast lump.,received 5 grey white linear cores measures 0.8 to 1.3cm. entire tissue processed.,section reveal linear cores of breast parenchyma with tumor infiltrating as tubules nests and cords composed of polygonal cells with enlarged hyperchromatic pleomorphic nucleus and scant to moderate cytoplasm. atypical mitosis are seen. foci of solid insitu carcinoma is seen. stroma shows desmoplasia and lymphomononuclear infiltrate.,biopsy from right breast lump. invasive carcinoma (nst) of ductal origin.grade 1 modified br score is 5 9.tubular formation : 2nuclear pleomorphism : 2mitotic figures : 1 ...... 5 9 ......
MR1816957,right breast mass.,biopsy from right breast mass.,received 4 grey white linear cores measures 0.8 to 1.2cm. entire tissue processed.,section reveal linear cores of breast parenchyma harboring tumor infiltrating in the form of nests and cords composed of polygonal cells with hyperchromatic nucleus and scant to moderate eosinophilic to clear cytoplasm cells show moderate pleomorphism. stroma shows desmoplasia.,right breast lump biopsy :invasive carcinoma nst of ductal origin. grade 2. modified br score is 6 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 1 ...... 6 9 ......
MR1816966,right breast lump birads iv.,biopsy from breast lump.,received 4 grey white linear cores measures 1.5 to 2cm. entire tissue processed.,sections show breast parenchyma with focal areas displaying features of useval and atypical ductal hyperplasia. the cells have moderate eosinophilic cytoplasm round to oval hyperchromatic nuclei with mild pleomorphic with focal areas showing loss of polarity. no foci of invasive carcinoma seen.,right breast lump biopsy :the possibility considered are :1. usual ductal hyperplasia (udh) 2. papillary lesion. suggest ihc.
MR1816995,left breast 2 0 clock lesion.,biopsy from left breast 2 0 clock lesion.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows tumor cells in cords tubules and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. large areas of sclerosis seen.,biopsy from left breast 2 0 clock lesion :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1817022,left breast lump.,biopsy from left breast.,received 7 grey white linear cores measures 0.6 to 1.2cm. entire tissue processed.,sections studied form linear cores harbors tumor cells arranged in nests acini and vague tubules. the cells have mildly pleomorphic nuclei with scant eosinophilic vacuolated cytoplasm. stroma shows desmoplasia focal mucin with scattered inflammatory infiltrate.,left breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1817026,right breast lump.,biopsy from right breast lump.,received multiple grey white linear cores measures 0.8 to 1.2cm. entire tissue processed.,section studied show breast parenchyma harboring invasive neoplasm arranged in glandular pattern trabecular and cords. the lesional cells are round moderate eosinophilic cytoplasm round hyperchromatic nucleus. few cells showing prominent nucleoli and intranuclear inclusion. stroma is desmoplastic and shows lymphoplasmacytic infiltration. foci of necrosis and hemorrhage noted.,biopsy from right lump.invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1817064,left breast lump.,biopsy from left breast lump.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is elastotic.,biopsy from left breast lump. invasive carcinoma. grade 2.modified br score is 7 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 ...... 7 9 ......
MR1817070,left breast lump.,biopsy from left breast.,received grey white linear cores measures 1.5 to 2cm. entire tissue processed.,sections studied from linear cores of breast parenchyma harbors tumor cells arranged in sheets tubules and nests. the cells have eosinophilic to clear cytoplasm and pleomorphic hyperchromatic nuclei. mitosis is occasional. adjacent breast parenchyma shows solid ductal carcinoma in situ. stroma shows desmoplasia with scattered lymphocytes.,biopsy from left breast lump.invasive carcinoma nos grade ii.modified br score is 7 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 ...... 7 9 ......
MR1817076,left breast lump carcinoma breast.,biopsy from left breast lump.,received 5 grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section show cores of breast tissue harboring invasive neoplasm in sheets nests and poorly formed glands. the cells show moderate cytoplasm and moderately pleomorphic hyperchromatic nuclei and prominent nucleoli. stroma is hyalinized with focal desmoplastic reaction.,left breast biopsy :invasive carcinoma nst grade ii.modified br score is 7 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 ...... 7 9 ......
MR1817121,carcinoma left breast.,a) breast conservative surgery wide excision of left breast lump.b) left sentinel lymph node biopsy.c) revised lateral margin.,a) received skin covered soft tissue bits measures 7x6x3cm.skin ellipse measures 4.5x0.5cm.distance from the margin:superior margin 1cm.inferior margin 1.2cm.medial margin 1.5cm.lateral margin 0.3cm.deep margin 1cm.cut surface shows grey white firm illdefined lesion measures 2.5x2x1cm.b) received fibrofatty tissue measures 3x2x2cm.isolated 3 lymph nodes. largest measures 1.5x1x1cm. entire tissue processed.c) received fibrofatty tissue measures 4x2.5x2cm. entire tissue processed.,section from the lesion show sheets nests and aggregates of tumor cells with moderate cytoplasm vesicular nuclei with prominent nucleoli. there is brisk mitosis. adjacent breast shows solid and comedo type high grade ductal carcinoma in situ. moderate intra and peritumoral lymphoplasmacytic infiltrate present.,a) breast conservative surgery wide excision of left breast lump:invasive ductal carcinoma (nst).modified bloom richardson score is 3+2+2 7 9grade ii.tumor measures 2.5cm in greatest dimension.invasive component measures 2.1cm.ductal carcinoma in situ present high grade comedo type measures 0.4cm.lymphovascular invasion is indeterminate.perineural invasion not identified.all resected margins including deep margin are free of tumor.b) left sentinel lymph node biopsy:3 nodes isolated are free of tumor 0 3c) revised lateral margin:free of tumor.1 lymph node present which is free of tumor 0 1.
MR1817150,left breast lump.,biopsy from left breast lump,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,the section shows linear cores of breast parenchyma with infiltration of tumor arranged in nests sheets and tubules. the tumor cells are round to ovoid with high n:c ratio with hyperchromatic ovoid nuclei and moderate eosinophilic cytoplasm. intervening stroma is desmoplastic and elastotic. dense surrounding lymphocytic infiltrate is seen foci of necrosis are seen. comedo type of ductal carcinoma in situ is seen.,biopsy form left breast lump.infiltrating ductal carcinoma nst grade 2. modified br score is 7 9.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 2 ...... 7 9 ......
MR1817168,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.8 to 1.5cm. entire tissue processed.,the section shows linear cores of breast parenchyma showing infiltration by tumor arranged in sheets and nests. the tumor cells are round to ovoid with high n:c ratio hyperchromatic ovoid nuclei with moderate to scant pale eosinophilic cytoplasm. tumor surrounded recurrent benign ducts. large areas of necrosis are seen. intervening desmoplastic stroma is seen.,invasive carcinoma nst grade iii.modified br score is 8 9.tubular formation : 3nuclear pleomorphism : 3mitotic figures : 2 ...... 8 9 ......
MR1817201,left breast carcinoma.,a) hot nodeb) blue +hot nodec) non blue non hot node.d) left mastectomy.e) revised base,a) received single node measures 1x0.5x0.5cm.cut surface fat infarction seen.b) received single lymph node measures 1.7x1x0.5cm.cut surface grey white homogeneousc) received fibrofatty tissue lymph node measures 0.5x0.4x0.4cm.d)received in : formalinprocedure :mastectomy laterality :lefttotal dimensions : medial to lateral :17cm superficial to deep :4.5cm superior to inferior :17cmskin ellipse :17x10cm nipple :normal scar surgical defect :absenttumor : singletumour size :3x3x2.5cm. location of tumor :upper outer quadrant margin of tumor :ill defined. deep margin :0.5cmmuscle : absent axillary tail :entry small part of axillary tail measures 2cm in length. e) received single grey brown soft tissue bits measures 1.1x1cm.suture tight away from tumor.,section from the breast lesion show sheets of tumor cells with moderate cytoplasm pleomorphic vesicular nuclei and prominent nucleoli n a desmoplastic stroma. the ducts show comedo type . ductal carcinoma in situ. adjacent breast show periductal lymphoid infiltrate. moderate intra and peritumoral lymphoplasmacytic infiltrate noted.,a) left sentinel hot node:one node identified is free of tumor (0 1)b)left sentinel blue +hot node:one node identified is free of tumor (0 1).c) left sentinel non blue non hot node:no node seen only fibrofatty tissue.d)left mastectomy:histological type: invasive ductal carcinoma grade:iiitumor measures maximum dimension 3cminvasive component measures 2.8cmductal carcinoma in situ measures 0.2cmmodified br score is 8 9tubule formation: 3 nuclear pleomorphism: 2mitotic figures: 3ductal carcinoma in situ present comedo type ( high grade)lymphovascular invasion not identified.perineural invasion not seen posterior resection margin is free of tumor.nipple and areola is unremarkable.sentinel lymph nodes: 2 lymph nodes metastasis :0(0 2).e) revised base muscle : is free of tumor.pathological stage: pt2snn0summary:invasive ductal carcinoma left breast. grade : iiilymph node status : sentinel nodes biopsy 2 nodes are free of tumor.
MR1817220,left breast lump.,biopsy from left breast lump.,received 4 grey white linear core measures 1 to 1.5cm. entire tissue processed.,linear core studied show breast parenchyma harboring lesion arranged in single file growth pattern. lesion cells have pleomorphic round to oval nucleus with smudgy chromatin prominent large nucleoli moderate eosinophilic cytoplasm. adjacent stroma show desmoplastic change.,biopsy from left breast lump.invasive carcinoma. (grade ii).
MR1817233,right breast lump.,biopsy from right breast core biopsy :,received 4 grey white linear core measures 0.8 x0.1cm. entire tissue processed.,section shows tumor cells in nests cords and cribriform pattern. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. large pools of intracellular mucin are seen.,biopsy from right breast core biopsy :invasive carcinoma with mucinous features grade 2. modified bloom richardson score is 6(3+2+1).
MR1817248,right breast mass carcinoma breast.,biopsy from right breast.,received 4 grey white linear core measures 1.5 to 2cm. entire tissue processed,section studied shows linear cores of fibroadipose tissue harboring an invasive neoplasm arranged in nests trabecular pattern. lesional cells are round to polygonal with moderate eosinophilic cytoplasm moderately pleomorphic hyperchromatic nucleus. few are showing intranuclear inclusions. stroma is desmoplastic and shows congested blood vessels and lymphoplasmacytic infiltrates.,biopsy from right breast. invasive carcinoma nstmodified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1817274,right breast lump carcinoma breast.,right breast core biopsy :,received 6 grey white to grey brown linear cores measures 0.8 x 1 cm. entire tissue processed.,section shows tumor cells in definite sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1817283,right breast lump.,biopsy from right breast lump.,received 4 grey white linear core measures 1 to 1.5cm. entire tissue processed.,the section show linear cores of breast parenchyma showing infiltration by tumor arranged predominantly in nests and cords. focaly in tubules .the tumor cells are round to ovoid with enlarged ovoid hyperchromatic nuclei and moderate clear to eosinophilic cytoplasm. intervening stroma is desmoplastic.,biopsy from right breast lump. :invasive carcinoma with lobular features. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1817285,left breast mass carcinoma breast.,left breast core biopsy.,received 6 grey white linear cores measures 1 1.5cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1817298,left breast lump.,biopsy from left breast.,received multiple linear core measures 1.5 to 2cm. entire tissue processed.,section studied shows linear cores of fibrous tissue with an infiltrating lesion arranged in tubules and focal nests. the cells are oval having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. occasional mitotic figures are discerned. stroma is desmoplastic with moderately dense lymphomononuclear infiltrate.,left breast biopsy :invasive carcinoma nst grade 1.modified bloom richardson score is 5 9tubule formation : 1nuclear pleomorphism : 2mitotic figures : 2 5 9 .........
MR1817308,left breast lump neoplastic.,biopsy from left breast lump.,received 4 grey white linear cores measures 1 to 1.5 cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an invasive neoplasm in cords and nests. the lesional cells are round with moderate eosinophilic cytoplasm and moderately pleomorphic hyperchromatic nucleus. few cells showing intranuclear inclusion. stroma is desmoplastic and shows lymphoplasmacytic infiltrates.,biopsy from left breast lump :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1817320,left breast lump carcinoma breast.,left breast core biopsy.,received 4 grey white linear cores measures 0.8 x 0.5 x 0.2 cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1817348,right breast mass.,biopsy from right breast mass.,received 4 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of tumor composed of nests of round to oval cells with high n:c ratio hyperchromatic nucleus and moderate eosinophilic to clear cytoplasm. nuclear pleomorphism is marked and mitosis discerned . stroma shows desmoplasia.,right breast lump biopsy :invasive carcinoma. no special type grade iimodified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1817368,right lump possibility of carcinoma breast.,right breast core biopsy.,received 5 grey white linear cores measures 1 1.5cm. entire tissue processed,section shows few atypical cells in sheets and tubular pattern. these cells have hyperchromatic nuclei and moderate amount of cytoplasm. rest of the tissue shows hyperplastic benign ductules.,right breast core biopsy:shows few atypical cells.suggest repeat biopsy or excision of the lump for further confirmation.
MR1817377,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received 6 grey white linear cores measures 0.8 to 1.1cm. entire tissue processed.,sections studied from linear cores composed of tumor cells arranged in sheets trabecular and occasional cells arranged in single file. the cells are mildly pleomorphic hyperchromatic nucleus with scant cytoplasm. stroma is desmoplastic with few foci shows hemorrhage and necrosis.,left breast lump :invasive carcinoma nst with lobular features grade ii.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1817389,left breast lump neoplastic.,biopsy from left breast lump.,received 4 grey white linear core measures 0.8 to 1cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1817402,case of bilateral breast lumps under evaluation.,a) left breast 10 o clock lesionb)left breast 12 o clock lesion c)left breast 3 o clock lesion.d) right breast lesion.,a) received wide excision specimen measures 7x5x3.5cm.cut surface shows illdefined and solid lesion measures 1.7x1.5x1.3cm.distance from the margin:superior margin 2cm.inferior margin 0.3cm.medial margin 1.5cm.lateral margin 1cm.deep margin 1cm.b) received single fibrofatty tissue measures 2x1x1cm. external surface is irregular cut surface is grey yellow. no gross lesion seen.c) received single fibrofatty tissue measures 2x1.8x1cm. external surface is irregular cut surface is grey yellow. no gross lesion seen.d) received fibrofatty tissue measures 5x3x2.5cm. external surface is irregular margins are executed.small cystic areas noted measures 0.6x0.5x0.5cm.distance from the margins:superior margin 1.2cm.inferior margin 0.6cm.medial margin 1.3cm.lateral margin 2.2cm.anterior margin 0.8cm.posterior (deep) margin 1cm.,a) section from the 10 o clock lesion show breast parenchyma with multiple ducts showing dilatation adenosis papillary projections into the lumen with fibrovascular cores. the cells show moderate eosinophilic cytoplasm vesicular nuclei with mild pleomorphism. there is focal paucity of myoepithelial cells. apocrine change also noted. many ducts show luminal secretions. few foci suspicious of ductal carcinoma in situ and invasion noted.b) sections from the 12 o clock lesion shows breast parenchyma with similar findings described above.c) sections from the 3 o clock lesion also show cystically dilated ducts with papillae. few ducts show solid type usual ductal hyperplasia.d) sections from right breast lesion also show extensive fibrocytic disease with few ducts showing papillary hyperplasia and intraductal papilloma.,a amp b amp c) left breast 10 o clock 12 o clock 3 o clock lesion:papillary neoplasm with adjacent fibrocystic changes.suspicious foci of ductal carcinoma in situ and invasive carcinoma present.suggest ihc.all resected margins are free of tumor.d) right breast lesion:fibrocystic disease with few ducts showing intraductal papilloma.resected margins are free of tumor.suggest ihc.
MR1817403,left breast lump.,biopsy from left breast lump.,received 5 grey white to grey brown linear core measures 1 to 1.5cm. entire tissue processed.,linear cores of breast tissue harboring neoplasm arranged in solid sheets. a few cell clusters are seen floating in lakes of mucin. the neoplastic cells exhibit moderate nuclear pleomorphism and have moderate cytoplasm .,biopsy from left breast lump. invasive carcinoma with mucinous features.grade 1.modified bloom richardson score is 5 9tubule formation : 3nuclear pleomorphism : 1mitotic figures : 1 5 9 .........
MR1817491,right breast mass.,right breast lesion biopsy.,received 4 grey white linear core measures 1.5 to 2cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an infiltrating lesion arranged predominantly in sheets. the cells are oval having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma is desmoplastic with moderately dense lymphomononuclear cell infiltrates. areas of hemorrhage and necrosis seen.,right breast lesion biopsy. :invasive carcinoma nst grade 3.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 8 9 .........
MR1817527,left breast mass carcinoma breast.,left breast lump biopsy.,received 5 grey white linear cores measures 0.8 1cm. entire tissue processed.,section studied shows linear cores of fibrous with an infiltrating lesion arranged in sheets and islands. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma is desmoplastic with moderately dense lymphomononuclear infiltrates and lymphoid aggregates . areas of hemorrhage and necrosis are seen.,left breast lump biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1817535,right breast mass carcinoma breast.,biopsy from right breast mass.,received 4 grey white linear core measures 1 to 1.2cm. entire tissue processed.,the sections show linear cores of fibrocollagenous tissue with infiltrating tumor arranged in nests and sheets. the tumor cells are round to ovoid with enlarged ovoid hyperchromatic nuclei and moderate pale eosinophilic cytoplasm. intervening stroma is desmoplastic.,right breast mass core biopsy :invasive carcinoma nst grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1817536,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,the sections shows linear cores of breast parenchyma showing tumor infiltrating in follicles nests and singly lying cells. the tumor cells are round to polygonal with increased n:c ratio hyperchromatic pleomorphic nuclei and moderate amount of cytoplasm. intervening stroma is desmoplastic.,right breast lump core biopsy :invasive carcinoma nst grade 1. modified bloom richardson score is 4 9tubule formation : 1nuclear pleomorphism : 2mitotic figures : 1 4 9 .........
MR1817537,carcinoma right breast.,a) right breast wide excision.b) sentinel hot node.c) sentinel blue + not node.d) extrafascial hysterectomy with bilateral salpingo oopherectomy.e) cystic lesion attached to rectum.,a) received single skin covered soft tissue bits measures 5.5x5x3cm.skin ellipse 4.5x1cm. cut surface grey white firm ill defined lesion measures 1.5x1.3x1cm.distance from the margin.superior margin 1cm.inferior margin 1cm.medial margin 1.2cm.lateral margin 0.8cm.deep margin 1cm.b) received single lymph node measures 1.5x1x1cm. cut surface shows fatty infiltrates. entire tissue processed.c) received single lymph node measures 1.6x1x1cm. cut surface is unremarkable. entire tissue processed.d) uterus dimensions: midline fundal serosa to ectocervix : 8.5cm.maximum intercornual : 5cm.maximum anterior to posterior : 3cm.cervix dimentions : 3.0x4cm.vaginal cuff : absent.cervix shape : normal right ovary : 1.5x1x0.5cm unremarkable.left ovary : 1.5x1x0.5cm unremarkable.right fallopian cyst : 1.5x1x0.5cm.right fallopian tube : 4cm unremarkable.left fallopian tube : 4cm unremarkable.right parametrium : 3.5x2x0.5cm.left parametrium : 3x2x0.5cm.endometrium description endometrial thickness : thickened 1cm.endometrial abnormalities : polyp measures 3x2x2cm.myometrium descriptionmyometrial depth : anterior 1.5cm posterior 1.5cm.lower uterine segment : shows stenosis.e) received cystic structure with attached fat measures 3x1.5x1cm. cut surface shows multi loculated cyst wall measures 0.1cm. entire tissue processed.,a) sections from the breast lesion show an invasive neoplasm in nests sheet like and tubular pattern. the cells show moderate cytoplasm vesicular nuclei with moderate pleomorphism and increased mitosis. there is adjacent comedo type ductal carcinoma in situ.b) sections from hot lymph nodes show reactive hyperplasia.c) section from blue + hot node show reactive hyperplasia.d) section from the endometrial polyp show complex glands of varying shapes and sizes with columnar cells showing loss of polarity nuclear atypia vesicular chromatin and prominent nucleoli. adjacent endometrium shows similar features. cervix and lower uterine segment are unremarkable. isolated tubules and ovaries show physiological changese) shows fibrocollagenous tissue with cystically dilated ducts lined by ciliated columnar cells with ovarian like stroma. no atypia seen.,a) right breast wide excision:invasive ductal carcinoma (nst).modified bloom richardson score is 3+2+2 7 9 grade ii.tumor measures 1.5cm in greatest dimension.invasive carcinoma measures 1cm.ductal carcinoma in situ present. comedo type high grade measuring 0.5cm.lymphovascular invasion not identified.perineural invasion not identified.all resected margins are free of tumor.b) sentinel hot node:1 node is free of tumor 0 1.c) sentinel blue + not node:1 node is free of tumor 0 1.d) extrafascial hysterectomy with bilateral salpingo oopherectomy:suggestive of endometrial polyp showing atypical hyperplasia (suggest ihc).no evidence of invasion.cervix and lower uterine segment are unremarkable bilateral tubes and ovaries are unremarkable.e) cystic lesion attached to rectum:suggestive of paratubal cyst. no evidence of malignancy.
MR1817555,left breast mass.,biopsy from left breast mass.,received 6 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections studied from linear cores of lesional tissue harbors tumor cells arranged predominantly in sheets nests and vague tubules. the cells are pleomorphic with increased n:c ratio large pleomorphic hyperchromatic nuclei and scant cytoplasm. occasional cells show prominent nucleoli. brisk atypical mitosis and comedonecrosis seen. stroma shows desmoplasia with lymphomononuclear infiltrate.,biopsy from left breast mass. invasive carcinoma nos (grade iii)modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9areas of comedonecrosis seen. .........
MR1817573,left breast mass carcinoma breast.,biopsy from left breast mass.,received 4 grey white linear core measures 0.8 to 1.2cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1817621,right breast mass carcinoma breast.,biopsy from right breast mass.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied from lesional tissue compose of tumor cells arranged in sheets. vague trabecular and nests. the cells are large hyperchromatic nucleoli and scant cytoplasm. brisk atypical mitosis and focal necrosis seen. stroma shows myxoid change. lymphoplasmacytic infiltrates with desmoplasia.,right breast mass.invasive carcinoma nos grade iii.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9 .........
MR1817623,carcinoma left breast post nact,left modified radical mastectomy post nact,received in : formalinprocedure : modified radical mastectomy laterality : lefttotal dimensions :medial to lateral :27cm superficial to deep :10cm superior to inferior:23cmskin ellipse : 21x16cm nipple : normal scar surgical defect :absenttumor : no obvious identified grossly.fibrotic area measures 1.6x1.3x1cm noted in 1 clock position deep margin :5cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail : 12x6x4cmsize of largest node :1.2x1x0.5cm,section studied show breast parenchyma with sheets and aggregates of foamy histiocytes dense lymphoplasmacytic infiltrate against a fibrotic background.,left modified radical mastectomy post nact:no residual tumor identified.therapy related changes seen.ductal carcinoma in situ is not seenlymphovascular emboli are not identified perineural invasion is not identified posterior resection margin is free of tumor.nipple and areola is unremarkablelymph nodes: 13 lymph nodes metastasis:0(0 13) . summary: left modified radical mastectomy post nact.(ypt0n0)no residual tumor identified.lymphnode status:0 13.
MR1817634,left breast mass carcinoma breast.,biopsy from left breast mass.,received 6 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1817645,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear core measures 1 to 1.5 cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring invasive neoplasm arranged in glandular pattern trabecular and cords. the lesional cells are round to polygonal with moderate eosinophilic cytoplasm round hyperchromatic nucleus some cells showing intranuclear inclusions. mitotic figures are noted. stroma is desmoplastic.,biopsy from right breast lump :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1817679,carcinoma right breast.,right modified radical mastectomy post nact.,received in : 10 nbf.procedure : right modified radical mastectomy post nact.laterality : right.total dimensions : medial to lateral 18cm. superficial to deep 6cm. superior to inferior 12cm.skin ellipse :12x5cm.nipple : normal scar surgical defect : absent.tumor : single.tumor size : 1x0.8x0.6cm. location of tumor : upper outer quadrant.margins of tumor : illdefined. deep margin : 1.5cm.muscle : absent adjacent breast : fibrofatty tissue. axillary tail : 7x7x3cm.size of largest node : 2x1.2x1cm. cut surface is deposit seen.,sections show breast parenchyma with an infiltrating lesion having cells in sheets. cells have moderate cytoplasm pleomorphic hyperchromatic to vesicular nuclei with prominent macronucleoli. atypical mitosis discerned (2 3 hpf). stroma is desmoplastic with moderate lymphomononuclear infiltrate and hemosiderin laden macrophages.,right modified radical mastectomy post nact:histological type: residual viable tumor present invasive carcinoma nst.grade:iiitumor measures maximum dimension 1cminvasive component measures 1cmmodified br score is 8 9tubule formation: 3nuclear pleomorphism: 2mitotic figures: 3ductal carcinoma in situ is absent.lymphovascular invasion is absent.perineural invasion is absent.posterior resection margin is free of tumor.nipple and areola is free of tumor.lymph nodes: 20 lymph nodes metastasis: 0 (0 20).pathological stage: ypt1n0summary:residual viable tumor present invasive carcinoma nst.tumor grade: iiilymphnode status: 20nodes. no metastatic deposit of tumor.
MR1817681,right breast mass carcinoma breast.,right breast biopsy.,received 6 grey white linear cores measures 0.8 to 1.3cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an invasive neoplasm arranged in glands trabecular and nests. the lesional cells are round with moderate eosinophilic to clear cytoplasm and pleomorphic hyperchromatic nuclei. some cells are showing intranuclear inclusion. mitotic figures are discernible stroma is desmoplastic.,right breast mass biopsy :invasion ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1817697,right breast lump carcinoma breast.,biopsy from right breast lump.,received four grey white linear cores measures 0.5 to 1.3 cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring an invasive neoplasm arranged in lobules trabecular and cords. the lesion cells are round to ovoid with scant eosinophilic cytoplasm and moderately pleomorphic hyperchromatic nucleus. stroma shows desmoplasia and lymphoplasmacytic infiltrates. extensive areas of hyalinisation and myxoid areas noted.,right breast biopsy :invasion carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1817708,left breast lump carcinoma breast.,biopsy from left breast lump.,received 6 grey white linear core measures 0.8 to 1.2cm. entire tissue processed.,the section shows linear cores of breast parenchyma nodule showing adenosis with intervening myxoid stroma. occasional ducts show multi laying and intraluminal micro papillary resections. the nuclei are enlarged pleomorphic hyperchromasia with moderate amount of cytoplasm. few ducts are distended with lumen filled with atypical ductal epithelial cells. occasional such ducts show central comedo necrosis. a few atypical cells are seen in cords.,biopsy from left breast lump. small focus of high grade ductal carcinoma in situ. needs larger tissue to exclude definite invasive component.
MR1817723,carcinoma right breast.,a) lumpectomy.b) sentinel node.c) sentinel node.d) right mastectomy.e) axillary clearance.,a) received single skin covered fibrofatty tissue measures 4x3x2cm.skin ellipse measures 3x1.5cm.cut surface show lesion measures 0.5x0.4cm.b) received single lymph node measures 0.6x0.5x0.5cm. cut surface is unremarkable.c) received fibrofatty tissue measures 4x3.5x1.5cm.4 lymph nodes isolated.largest measures 1.5x0.6x0.5cm. cut surface is unremarkable.d) received in : 10 nbf.procedure : right mastectomy.laterality : right.total dimensions : medial to lateral 24cm. superficial to deep 19cm. superior to inferior 5cm.skin ellipse : 15x10cm show defect measures 4x2.5cm. nipple : normal scar surgical defect : lympectomy bed present measures 4x4x3cm.tumor : single.tumour size : well circumscribed nodules seen subcutaneosly in nipple areolar region measures 0.5x0.5x0.5cm. cut surface of nodules grey white to yellowish. distance between two nodules 0.2 cm deep margin : 4cm.muscle : absent adjacent breast : fibrofatty tissue. e) received fibrofatty tissue measures 10x7x5cm.largest measures 1.5x0.8x0.5cm. cut surface is grey white.,sections show breast parenchyma with an infiltrative lesion with cells arranged in cords and trabecular. cells have scant to moderate cytoplasm with pleomorphic hyperchromatic nuclei and prominent nucleoli. atypical mitotic figures are discerned (3 4 hpf). intensive areas of ductal carcinoma in situ (solid comedo) with intermediate nuclear grade noted.,a) lumpectomy:invasive ductal carcinoma with extensive ducal carcinoma in situ (solid comedo).b c) sentinel node:one out of three shows metastatic deposit (1 3).d) right mastectomy:invasive ductal carcinoma grade ii.modified br score is 7 9tubule formation: 3nuclear pleomorphism: 2mitotic figures: 2tumor measures 1.8cm in greatest dimension and is located in the central quadrant. invasive carcinoma measures 0.8cm. ductal carcinoma in situ measures 1cm.ductal carcinoma in situ is present (solid comedo cribriform papillary) intermediate nuclear grade.lymphovascular invasion is present.perineural invasion is present.posterior resection margin is free of tumor.nipple and areola is free of tumor.total lymph nodes: 15 lymph nodes metastasis: 1 (1 15). 3 sentinel nodes. one of them shows metastatic deposit (1 3).e) axillary clearance:all 12 nodes isolated are free of tumor (0 12).pathological stage: pt1n1
MR1817747,right breast lump carcinoma breast.,right breast core biopsy.,received multiple linear core measures 0.8 to 0.1cm. entire tissue processed.,section shows tumor cells in sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6 (3+2+1).
MR1817765,left breast lesion.,biopsy from left breast mass.,received 6 grey white linear core measures 0.5 to 1.3cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring an neoplasm arranged in glandular pattern nests trabecular. the lesional cells are round with abundant pale eosinophilic cytoplasm round to ovoid nucleus. stroma shows desmoplasia and lymphoplasmacytic infiltrates. perineural invasion is identified.,left breast mass biopsy :invasion ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2). perineural invasion is identified. lymphovascular invasion is not identified.
MR1817784,right breast mass carcinoma breast.,biopsy from right breast mass.,received 4 grey white to grey yellow linear core measures 0.8 to 1cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in clumps and nests the neoplastic cells shows moderate cytoplasm pleomorphic hyperchromatic nuclei and prominent nucleoli. few cells show apocrine change. tumor infiltrates adipose tissue. stroma is desmoplastic.,right breast mass biopsy :invasive carcinoma nst grade 2. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1817802,left breast mass.,biopsy from left breast mass.,received 4 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring invasive neoplasm arranged in solid nests and vague glandular pattern. individual cells have moderate eosinophilic to clear cytoplasm round hyperchromatic nucleus and few cells showing prominent nucleoli. mitotic figures are noted.,biopsy from left breast mass: invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1817804,right breast lump carcinoma breast.,biopsy from right breast lump.,received 3 grey white to grey brown linear core measures 1 to 1.5cm. entire tissue processed.,sections studied shows linear cores of fibrocollagenous tissue harboring invasive neoplasm arranged in diffuse sheets glandular pattern. the cells are polygonal with abundant eosinophilic cytoplasm pleomorphic central to eccentrically placed hyperchromatic nucleus. mitotic figures are seen. stroma shows desmoplasia.,biopsy from right breast lump :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1817814,carcinoma left breast.,a) left wide local excision.b) sentinel lymph nodes.,a) received in : 10 nbf.procedure : left wide local excision.laterality : left.total dimensions : 7x5.5x5cm.skin ellipse : 5x1cm. nipple : normal scar surgical defect : absent.tumor : singletumor size : 1.5x1x1cm.deep margin : 0.5cm. muscle : absent.adjacent breast : fibrofatty tissue. total number of nodes : 2 sentinel nodes.size of largest node : 1.5x0.5x0.5cm.distance from the margin :superior margin : 2cm.inferior margin : 2.5cm.medial margin : 3cm.lateral margin : 3.5cm.deep margin : 0.5cm.b) received 2 lymph nodes.largest measures 1.5x0.5x0.5cm.,sections show breast parenchyma with tumor infiltrating in the form of tubules nests and cords composed of polygonal cells with moderate pleomorphism high n:c ratio vesicular nucleus and prominent nucleolus. mitosis are sparse. necrosis is not seen. stroma shows desmoplasia.,left breast wide local excision.histological type: invasive ductal carcinoma nst.grade: 1tumor measures maximum dimension 1.5cm.invasive component measures 1.2cm.ductal carcinoma in situ measures0.3cm.modified br score is 5 9tubule formation: 2nuclear pleomorphism: 2mitotic figures: 1ductal carcinoma in situ is solid type.lymphovascular invasion is not identified.perineural invasion is not identified.posterior resection margin is free of tumor.superior inferior medial and lateral margins are free from the tumor.pathological stage: pt1snn0summary:invasive ductal carcinoma nst left breast.all resected margins are free from the tumor.tumor grade: 1sentinel lymph nodes : 0 2b) sentinel lymph nodes:2 lymph nodes are isolated and free of tumor.
MR1817835,right breast lump neoplastic.,biopsy from right breast lump.,received 4 grey white linear core measures 1x1.5cm. entire tissue processed.,section shows cores of congest parenchyma harboring in invasive neoplasm in nests and trabecular the neoplastic cells show eosinophilic to clear cytoplasm round hyperchromatic nuclei with moderate pleomorphism and prominent nucleoli stroma is desmoplastic there is mild peritumoral lymphocytic infiltrate.,biopsy from right breast lump.invasive carcinoma nst grade ii.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1817839,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received 4 grey white to grey brown linear core measures 0.5 to 1cm entire tissue processed.,section cores of fibro adipose tissue harboring an invasive neoplasm in sheets trabecular. the neoplastic cells shows with defined cell borders moderate cytoplasm round hyperchromatic nuclei and prominent nucleoli. few cells show plasmacytoid appearance.,left breast lump biopsy :invasive carcinoma (nst)modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 .........
MR1817887,right breast lump carcinoma breast.,right breast lump biopsy.,received 3 grey white to grey brown linear core measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring invasive tumor in the form of nests and focal cribriform pattern. the cells are round to plasmacytoid with moderate pale to dense eosinophilic cytoplasm and enlarged hyperchromatic nucleus. nuclear pleomorphic is mild and mitosis are space. stroma shows desmoplasia occasional duct shows cystic change. foci of ductal carcinoma in situ are seen.,invasive carcinoma. mbr score (3+1+1) 5 9. grade ii.
MR1817912,right breast lump carcinoma breast.,right breast lump.,received 4 grey white to linear core measures 1 to 1.5cm entire tissue processed.,section studied shows linear cores of lesional tissue harboring an invasive neoplasm composed of tumor cells arranged in tubules nests and scattered individual cells. the cells have scant cytoplasm and hyperchromatic irregular nucleus. foci of solid ductal carcinoma in situ with comedonecrosis seen. stroma shows focal myxoid change with dense desmoplasia with lot of crush artifacts.,right breast lump.invasive carcinoma nos with slid ductal carcinoma in situ grade ii.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 .........
MR1817915,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section studied form linear cores of lesional tissue compose of tumor cells arranged in vague tubules nests and scattered isolated cells. the cells have scant cytoplasm large pleomorphic hyperchromatic nuclei. brisk atypical mitosis noted.stroma shows desmoplasia.,left breast lump :invasive carcinoma nos grade iii. modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9 .........
MR1817922,left breast lesion.,left breast biopsy.,received 5 grey white linear core measures 0.5 to 1cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in nests trabecular and focal tubules. the cells show moderate cytoplasm pleomorphic nucleoli with moderate atypia and increased mitosis.stroma is desmoplastic.,left breast biopsy :invasive carcinoma (nst)modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1817943,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear core measures 1 to 1.5cm. entire tissue processed.,sections studied from linear core of lesional tissue composed atypical cells composed of variably dilated ducts. the cells are arranged in sheets having scant eosinophilic cytoplasm and round to oval hyperchromatic mildly pleomorphic nucleus. the ducts are lined by myoepithelial cells. foci of invasive carcinoma is also seen. composed of nests of atypical cells having scant cytoplasm and hyperchromatic irregular nucleus. stroma shows desmoplasia.,right breast lump biopsy :invasive carcinoma nos grade ii with solid ductal carcinoma in situ.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1817993,right breast mass carcinoma breast.,biopsy from right breast mass.,received 3 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section studied from linear ores of lesional tisue harbors an invasive neoplasm with cells arranged predominantly in sheets and in nests. the cells are have increase n:c ratio pleomorphic with moderate amount of pale eosinophilic cytoplasm and large irregular overlapping hyperchromatic nucleus. brisk atypical mitosis noted. stroma shows desmoplasia.,biopsy from right breast mass.invasive carcinoma nos grade ii. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1818002,left breast mass.,biopsy from left breast mass.,received 4 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section studied from linear cores of lesional tissue harboring an invasive neoplasm composed of tiny foci of tumor cells arranged in nests and scattered isolated cells. the cells are irregular with scant cytoplasm and large hyperchromatic nuclei stroma shows large areas dense desmoplasia with scattered lymphocytes .,left breast mass biopsy :invasive carcinoma nuclear grade ii.in view of tiny foci of tumor tissue.suggest repeat biopsy to do ihc.
MR1818025,carcinoma left breast.,a) left breast wide local excision.left sentinel lymph node biopsy.b) blue + hot node.c) hot node.d) additional sentinel node,a) received skin covered fibrofatty tissue measures 9x6x6cm.skin ellipse 6x2cm.cut surface shows grey white to grey yellow well circumscribed tumor 2x1x1cm.b) isolated 2 lymph nodes largest measures 2x1.5x1cm.distance from the margins:superior margin 2cm.inferior margin 4cm.medial margin 3cm.lateral margin 2.5cm.deep margin 1cm.c) received 2 lymph nodes. largest measures 0.8x0.5x0.5cm.cut surface is unremarkable. entire tissue processed.d) received fibrofatty tissue measures 3.5x2x0.5cm.isolated lymph node single largest measures 0.5x0.2x0.2cm.,sections from the lesion show partially circumscribed neoplasm in diffuse sheets and trabeculae. the cells show illdefined cell borders moderate cytoplasm and prominent nucleoli. there is moderate peritumoral lymphocytic infiltrate. adjacent breast show small foci of solid type ductal carcinoma in situ.,a) left breast wide local excision:invasive carcinoma with medullary features.modified bloom richardson score is 3+3+3 9 9. grade iii.tumor measures 2cm in greatest dimension.small focus of ductal carcinoma in situ solid type high grade noted measures 0.3cm.lymphovascular invasion is present.perineural invasion is not identified.all resected margins are free of tumor.left sentinel lymph node biopsy.b) blue + hot node:1 out of 2 nodes show metastasis measures 0.2cm. no perinodal spread (1 2).c) hot node:2 nodes are free of tumor (0 2).d) additional sentinel node:1 node isolated is free of tumor (0 1).
MR1818028,right breast mass carcinoma breast.,biopsy from left breast mass.,received 3 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrous tissue with an infiltrating lesion arranged in nests and islands. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few.mitotic figures are (9 10 10hpf) discerned. stroma is desmoplastic with areas of hemorrhage and necrosis.,biopsy from left breast mass :invasive carcinoma nst grade 2.modified bloom richardson score is 7 9 grade ii.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 .............. 7 9 ................
MR1818050,right breast mass.,biopsy from right breast mass.,received 6 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section reveal linear core of breast parenchyma harboring an invasive tumor composed of tubules lined by cuboidal to columnar cells with high n:c ratio and moderate cytoplasm. focal cribriform pattern is seen. foci of ductal carcinoma in situ is seen. mitosis are sparse nuclear pleomorphism is mild. stroma shows desmoplasia and lymphomononuclear infiltrate.,biopsy from right breast mass.invasive ductal carcinoma (nst). grade 2.modified bloom richardson score is 3 9 grade i.tubule formation : 1nuclear pleomorphism : 1mitotic figures : 1 ........... 3 9 ............
MR1818054,left breast mass.,biopsy from left breast mass.,received 5 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section shows breast parenchyma harboring invasive tumor in the nests. composed of round to oval cells with pleomorphic hyperchromatic nucleus and scant to moderate cytoplasm. atypical mitosis and foci of necrosis seen. stroma shows desmoplasia.,biopsy from left breast mass.invasive ductal carcinoma (nst). grade 3. modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 ........
MR1818055,right breast lump neoplastic.,biopsy from right breast lump.,received 6 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section reveal linear core of breast parenchyma harboring invasive tumor composed of sheets cords and occasional nests composed of round to oval cells with high n:c ratio scant to moderate cytoplasm. the cells show moderate nuclear pleomorphism and mitosis 8 10 hpf. foci of solid ductal carcinoma in situ are seen. stroma shows lymphomononuclear infiltrate and lymphoid aggregates.,right breast lump biopsy :invasive carcinoma with ductal carcinoma in situ. grade 2. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........suggest ihc.
MR1818056,left breast mass.,biopsy from left breast mass.,received 4 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section reveal linear core of breast parenchyma harboring invasive tumor in the form of nests sheets and focal micropapillary pattern. the cells are round to oval with hyperchromatic nucleus and scant to moderate cytoplasm. nuclear plemorphism is mild and mitosis are 2 3 10hpf. large foci of necrosis are seen. stroma shows desmoplasia and lymphomononuclear infiltrate.,biopsy from left breast mass.invasive ductal carcinoma (nst). grade 2.modified bloom richardson score is 6 9 grade ii.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 ............ 6 9 .............
MR1818097,left breast lump carcinoma breast.,left breast lump biopsy.,received 4 grey white linear core measures 0.8 to 1.3cm. entire tissue processed.,sections studied show from linear cores of lesional tissue harbors an invasive neoplasm arranged in sheets. the cells have scant eosinophilic to clear cytoplasm and large irregular vesicular nucleus with eosinophilic prominent nucleoli. brisk atypia. mitosis noted stroma shows extensive desmoplasia.,left breast lump biopsy :left breast lump. invasive carcinoma nos grade ii. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1818106,left breast mass.,biopsy from left breast mass.,received 4 grey white linear core measures 1x1.5cm. entire tissue processed.,sections studied from linear cores of lesional tissue composed of tumor cells arranged in sheets nests and scattered isolated cells. the cells are large irregular with scant cytoplasm and large hyperchromatic irregular nuclei. brisk atypical mitosis noted. stroma shows desmoplasia with lymphocytic infiltrates. foci of solid ductal carcinoma is also noted.,biopsy from left breast mass. invasive carcinoma nos grade 3with solid ductal carcinoma in situ. modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9 .........
MR1818129,carcinoma right breast.,right breast biopsy.,received 4 linear core measures 1 to 1.5cm. entire tissue processed. :,section studied shows linear cores of fibrous tissue with an infiltrating lesion arranged predominantly in sheets and islands. the cells are large pleomorphic having moderate amount of cytoplasm hyperchromatic pleomorphic nucleus and inconspicuous nucleoli. mitotic figures are discerned. stroma is desmoplastic with areas of hemorrhage and necrosis.,right breast biopsy :invasive carcinoma nst grade 3.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9 .........
MR1818137,carcinoma right breast.,a) right breast wide local excision.b) sentinel node dissection.c) hot node.,a) received skin covered soft tissue mass measures 12x7x5cm.skin ellipse 7x2.5cm. surface shows shows grey white ill defined nodule measures 2.5x2x1.8cm.distance from the margin:superior margin 1.5cm.inferior margin 1.8cm.medial margin 2cm.lateral margin 1.5cm.deep margin 0.3cm.b) received fibrofatty tissue measures 2x2x1cm.isolated 2 lymph nodes largest measures 1.2x1x1cm. cut surface is unremarkable. entire tissue processed.c) received 2 lymph nodes largest measures 2x1x1cm.cut surface shows fatty infiltration. entire tissue processed.,section from the lesion show viable tumor arranged in nests and tubules in a myxoid and mucoid stroma. the tubules are lined by cuboidal to columnar cells with moderate cytoplasm vesicular nuclei and prominent nucleoli. these are areas of calcification and necrosis noted. occasional ducts shows solid type intermediate grade ductal carcinoma in situ. focal areas show tumor cells floating in pools of mucin.,a) right breast wide local excision:invasive ductal carcinoma with mucinous carcinoma features (60 ).tumor measures 2.5cm.modified bloom richardson score is 3+2+1 6 6. grade ii.invasive component measures 2.2cm.ductal carcinoma in situ present low grade measures 0.3cm.lymphovascular invasion is not identified.perineural invasion is not identified.all resected margins are free of tumor.b) sentinel node dissection:blue + hot node.2 nodes are free of tumor (0 2).c) hot node:2 nodes are free of tumor (0 2).total 4 nodes are free of tumor (0 4).
MR1818199,case of left breast carcinoma.,a) left breast wide excision. b c) left breast carcinoma.,a) received skin increased fibro fatty measures 6x4x3cm. skin ellipse measures 5x1cm. cutsurface grey white tumor measures 2x1.5x1cm. entire tissue processed. distance from margins :superior margin : 0.8cminferior margin : 1.5cmmedial margin : 3.5cmlateral margin : 4cmdeep margin :1.5cmb) received single lymph node 2.5x1x0.5cm. cutsurface fatty infiltration. entire tissue processed. c) received single lymph node measures 1.2x0.8x0.5cm. entire tissue processed.,sections from the breast lesion show tumor cells in nests trabeculae and cribriform tubules in a desmoplastic stroma. the cells are columnar showing moderate cytoplasm round nuclei with moderate pleomorphism and increased mitosis. few occasional ducts show ductal carcinoma in situ solid (intermediate grade).,a) left breast wide local excision. invasive ductal carcinoma (nst) grade ii.modified bloom richardson score is (3+2+2) 7 9tumor measures 2cm in greatest dimensionductal carcinoma insitu is seen solid type intermediate grade. all resected margins including deep margin are free of tumor. lymphovascular invasion not identified. perineural invasion is not identified. left sentinel node decision. b)hot nodes isolated is free of tumor 0 1c) blue + hot note : 1 node isolated is free of tumor 0 1.
MR1818204,right breast lump carcinoma breast.,biopsy from right breast lump.,received 3 linear core measures 1 to 1.2cm. entire tissue processed.,section studied shows linear cores of lesional tissue harboring invasive neoplasm arranged in sheets and forming vague tubules and nests. the cells are pleomorphic with scant cytoplasm and large irregular hyperchromatic nucleus. occasional cells show prominent eosinophilic nucleoli. brisk atypical mitosis noted. stroma shows scattered lymphocytic infiltration with desmoplasia.,right breast lump biopsy :invasive carcinoma nos grade iii.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9 .........
MR1818211,right breast lump.,a) right breast lump wide local excision.b) re excised deep margin.c) right sentinel lymph node dissection.,a) received single fibrofatty tissue measures 6x4x2cm.cut surface shows illdefined grey white lesion measures 1.5x1x1cm.distance from the margin:superior margin 0.8cm.inferior margin 1cm.medial margin 1.3cm.lateral margin 1.3cm.deep margin 0.3cm.b) received single fibrofatty tissue measures 3x2x1cm. cut surface is unremarkable.c) received multiple fibrofatty tissue altogether measures 3x2x2cm.largest lymph node measures 2x1.5x1cm.cut surface fatty infiltration seen. entire tissue processed.,a) section studied shows breast parenchyma showing extensive areas of ductal carcinoma in situ arranged in papillary solid cribriform and comedo pattern. the cells are round with moderate cytoplasm and moderately pleomorphic nucleus. stroma shows mild inflammatory infiltrates and congested blood vessels. all the resected margins are free of tumor.b) revised deep margin is free of tumor.c) sections from right sentinel lymph nodes show 6 lymph nodes. none show metastatic deposits of tumor (0 6).,a) right breast lump wide local excision:high grade ductal carcinoma in situ papillary solid cribriform and comedo pattern.nuclear grade iii.the lesion measures 1.5cm in greatest dimension.no lymphovascular invasion seen.no perineural invasion seen.all the resected margins are free of tumor.adjacent breast shows intraductal papilloma.b) re excised deep margin:free of tumor.c) right sentinel lymph node dissection:identified six lymph nodes. none show metastatic deposits of tumor (0 6).
MR1818252,left breast lump.,biopsy from left breast.,received 4 grey white linear core measures 0.5 to 1.5cm. entire tissue processed.,sections studied from linear cores of lesional tissue harbors an invasive neoplasm arranged in sheets and clusters. the cells are large pleomorphic with abundant pale eosinophilic clear cytoplasm and large irregular hyperchromatic clear cytoplasm and large irregular hyperchromatic nuclei. brisk atypical mitosis seen. stroma shows desmoplasia.,left breast lump biopsy :invasive carcinoma nos grade ii.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1818277,known case of carcinoma right breast post mrm.,right parasternal subcutaneous nodule biopsy.,received multiple linear core measures 1.2 to 1.5cm. entire tissue processed.,sections shows tumor cells in sheets nests and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right parasternal subcutaneous nodule biopsy:suggestive of metastatic tumor deposit in known and treated case of carcinoma right breast.
MR1818287,left breast lump carcinoma breast.,left breast core biopsy.,received multiple grey white linear cores measures 0.8 to 0.1cm. entire tissue processed.,sections shows tumor cells in sheets nests and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1818306,right breast lump.,biopsy from right breast lump.,received 4 grey linear cores measures 0.8 to 1.2cm. entire tissue processed.,the section shows linear cores of breast parenchyma showing marked hyalinization and scant tumor infiltrating in nests cords and tubules. the tumor cells are round to ovoid with enlarged hyperchromatic nuclei and moderate to scant cytoplasm.,right breast linear core biopsy. invasive carcinoma nst grade 1.modified bloom richardson score is 4 9tubule formation : 2nuclear pleomorphism : 1mitotic figures : 1 4 9 .........
MR1818307,known case of carcinoma breast.,biopsy from gastric growth.,received multiple grey white mucosa bits altogether measures 1x0.6x0.2cm. entire tissue processed.,sections show fragments of gastric mucosa with tumor cell arranged as diffuse sheets and focal glandular pattern. the tumor cells are polygonal with vesicular pleomorphic nuclei prominent nucleoli and moderate cytoplasm. atypical mitosis are seen.,biopsy from gastric growth:positive for malignancy.suggestive of poorly differentiated carcinoma. primary. metastasis.suggest further workup.
MR1818309,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey linear core measures 1.5 to 1cm. entire tissue processed.,linear cores of breast tissue harboring neoplasm arranged in cords and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm foci of high grade ductal carcinoma in situ (comedo pattern) seen.,invasive carcinoma right breast grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1818340,carcinoma right breast.,a) right breast right modified radical mastectomy.b) intramammary lymph node satellite lesion adjacent to primary.,a)received in : formalin.procedure : modified radical mastectomy. laterality : right. total dimensions : medial to lateral :21cm. superficial to deep :5.5cm. superior to inferior :19cm.skin ellipse : 14 x 9 cm. nipple : normal scar surgical defect : absent.tumor : single.tumour size : 3.5 x 3 x 2 cm. location of tumor : lower outer quadrant. margin of tumor : illdentified. deep margin : 2 cm.muscle : absent.adjacent breast : fibrofatty tissue. axillary tail :10 x 6 x 2 cm.size of largest node : 2 x 1.5 x 1 cm cut surface deposit seen.representative sections are submitted. b) received fibrofatty tissue measures 1.5 x 1 x 0.5 cm. entire tissue processed.cut surface grey white,section shows tumor cells sheets nests and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm lymphovascular invasion is identified perineural invasion is indeterminate,right breast right modified radical mastectomy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). tumor is located in the lower outer quadrant. tumor measures 3.5 cm in greatest dimension. lymphovascular invasion is identified. perineural invasion is indeterminate. posterior resection margins is free of tumor. nipple and areola are free tumor.lymph nodes:sixteen out of twenty are lymph nodes show metastatic tumor deposits with extranodal extension(16 21). size of the largest tumor deposit measures 1.4cm in greatest dimension.b) intramammary lymph node satellite lesion adjacent to primary:shows tumor deposit measuring 0.6 cm in greatest dimension.
MR1818377,left breast lump carcinoma breast.,biopsy from left breast lump.,left breast biopsy.,section studied shows linear cores of fibrous tissue harboring an infiltrating lesion arranged in nests tubules and cords. the cells are oval having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma shows extensive desmoplasia with dense lymphomononuclear infiltrates.,biopsy from left breast lump. invasive carcinoma nst grade 1.modified bloom richardson score is 5 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9 .........
MR1818382,right breast lump carcinoma breast.,biopsy from right breast lump.,received 3 linear core measures 1 to 1.4cm. entire tissue processed.,section shows linear cores of poorly processed tissue with marked crushing artifacts. no definite opinion possible in view of marked crushing artifact.,right breast lump :inadequate for evaluation with extensive crush artifact. suggest repeat biopsy.
MR1818398,left breast lump possibility of carcinoma breast.,left breast biopsy.,received 3 linear core measures 1 to 1.2cm. entire tissue processed.,section studied show linear cores of fibrous tissue harboring an infiltrating lesion arranged in nests islands and sheets of atypical oval cells pleomorphic nucleus and prominent nucleoli is few. stroma is desmoplastic with areas of hemorrhage and necrosis.,left breast biopsy :invasive carcinoma nst grade 2. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1818407,left breast lump carcinoma breast.,left breast lump biopsy.,received 4 grey white linear core measures 1 to 1.4cm. entire tissue processed.,section shows linear core of breast parenchyma harboring infiltrative lesion composed of nests and tubules lined by cuboidal to polygonal cells with marked pleomorphism high n:c ratio vesicular nucleus prominent nucleolus and moderate cytoplasm. mitosis are 12 14 hpf.,left breast lump biopsy.invasive ductal carcinoma (nst) grade 3modified bloom richardson score is 8 9tubule formation : 2nuclear pleomorphism : 3mitotic figures : 3 8 9 .........
MR1818438,right breast lump carcinoma breast.,right breast biopsy.,received multiple linear core measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrous tissue harboring an infiltrating lesions arranged in nests and islands. the cells are oval having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few mitotic figures are discerned. stroma is desmoplastic with moderately dense lymphomononuclear infiltrate.,right breast biopsy:invasive carcinoma nst grade 2.tubular formation 3.mitotic activity 2nuclear pleomorphism 2 7 9
MR1818496,left axillary mass neoplastic.,biopsy from axillary mass.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,the sections show linear cores showing large areas of necrosis and atypical cells in nests and sheets. the cells are cuboidal to polygonal with enlarged hyperchromatic pleomorphic nuclei and moderate to scant cytoplasm.,left axillary mass core biopsy :suggestive of poorly differentiated carcinoma most possible from breast.
MR1818503,right breast lump carcinoma breast.,right breast lump biopsy.,received 4 grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section studied from linear cores of lesional tissue harbors an invasive neoplasm composed of tumor cells arranged in a single file and focally forming acini and tubules. the cells are pleomorphic having scant clear to eosinophilic cytoplasm is irregular hyperchromatic nuclei. brisk atypical mitosis noted. stroma shows focal myxoid change with dense desmoplasia.,right breast lump biopsy :invasive carcinoma nos with lobular features mbr score (2+2+2) 6 9 .grade ii.
MR1818537,carcinoma breast.,biopsy from right breast mass.,received 4 grey white linear cores measures 1x 1.5cm. entire tissue processed.,section studied shows sheets of malignant cells. the cells are pleomorphic having scant pale eosinophilic to clear cytoplasm and large irregular hyperchromatic nuclei. brisk atypical mitosis and eosinophilic prominent nucleoli seen. stroma shows scattered lymphocytic infiltrate with desmoplasia. focal calcified areas are noted.,biopsy from right breast mass:invasive carcinoma nst grade iii.modified bloom richardson score 3+3+2 8 9.
MR1818565,right breast lesion.,right breast biopsy.,received five grey white linear core measures 1.5 to 1.8 cm. entire tissue processed.,section studied shows linear cores of fibrous tissue harboring an infiltrating lesion arranged in islands and nests. the cells are oval having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma is desmoplastic with mild lymphomononuclear infiltrates.,right breast biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1818608,right breast lump.,biopsy from right breast lump.,right breast lump biopsy.,sections show multiple linear cores of fibrous tissue harboring an infiltrative lesion with cells arranged in clusters cords trabecular and singles. the cells have scant to moderate eosinophilic cytoplasm pleomorphic hyperchromatic nuclei with prominent nucleoli mitotic figures are discerned. surrounding stroma is desmoplastic with mild lymphomononuclear infiltrate. no lymphovascular perineural invasion seen.,right breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1818616,left breast mass carcinoma breast.,biopsy from left breast .,received 3 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring invasive tumor composed of round to oval cells arranged in nests cords sheets and few tubules. these cells show enlarged hyperchromatic nucleus conspicuous nucleolus and moderate pale to eosinophilic cytoplasm nuclear pleomorphism is mild. mitosis are sparse. stroma shows desmoplasia.,left breast lump biopsy :invasive ductal carcinoma nst.mbr score (2+1+1) 4 9 grade i.
MR1818676,left breast lump.,left breast biopsy.,received multiple grey white linear core measures 1 to 1.2cm. entire tissue processed.,section studied show linear cores of fibrous tissue with an infiltrating lesion arranged in sheets and nests. the cells are oval having moderate amount of cytoplasm and hyperchromatic pleomorphic nucleus. mitotic figures are discerned (8 9 10hpf). stroma is desmoplastic with areas of hemorrhage and necrosis.,left breast biopsy : poorly differentiated malignancy. invasive carcinoma nst grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1818718,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear core measures 1 to 1.2cm. entire tissue processed.,section shows tumor cells in sheets and nests. individual tumor cells have hyperchromatic nuclei and moderate amount of cytoplasm. few cells with bizarre nuclei and multinucleated giant cells are seen.,right breast lump core biopsy :invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+3+2).
MR1818720,right breast lump carcinoma breast.,biopsy from right breast.,received 4 linear cores measures 0.4 to 0.5cm. entire tissue processed.,the section shows tumor cores of breast parenchyma showing dilated cystic spaces with lining epithelium showing composed papillary unfolding cribriforming and areas showing multi layering . papillae are lined by atypical cuboidal to columnar epithelium with high n:c ratio hyperchromatic ovoid nuclei and moderate amount of eosinophilic cytoplasm. surrounding stroma is densely sclerotic and show occasional nests and tubules of atypical cells.,right breast lump :papillary neoplasm. suggest wide excision.
MR1818754,left breast lump carcinoma breast.,biopsy from left breast lump.,received 3 linear cores measures 2.5 to 1.6cm.,the section shows linear cores of breast parenchyma showing tumor infiltrating in nests and cord. the tumor cells are round to ovoid with high n:c ratio hyperchromatic pleomorphic ovoid nuclei and moderate amount of eosinophi8lic cytoplasm. the tumor cells infiltrate in targetoid pattern surrounding benign ducts focally. intervening stroma shows hyalinization.,biopsy from left breast lump :features suggestive of carcinoma nst of ductal origin modified bloom richardson score is 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1818807,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear core measures 1 to 1.5cm. entire tissue processed.,sections studied from linear cores of lesional tissue harbors an invasive neoplasm arranged in tubular trabecular and in nests against a desmoplastic stroma. the cells are pleomorphic with scant cytoplasm and large hyperchromatic irregular nuclei. occasional cells show prominent eosinophilic nucleoli. also seen are few dilated glands with mucoid secretions. lymphocytic and myxoid degeneration in stroma.,left breast lump biopsy. invasive carcinoma nst. (grade ii)modified bloom richardson score is (2+2+2) 6 9.
MR1818822,light breast lump.,left breast lump biopsy.,received 4 linear core measures 1 to 1.2cm. entire tissue processed.,section studied shows linear cores of fibrous tissue with an infiltrating lesion arranged in focal tubules cords and islands. the cells are oval having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma is desmoplastic with scattered lymphomononuclear infiltrates.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6 (2+2+2).
MR1818826,right breast lump carcinoma breast.,right breast biopsy.,received 3 linear core measures 0.5 to 0.8cm. entire tissue processed.,section studied shows linear cores of fibrous tissue with extensive areas of desmoplasia and hyalinisation harboring tiny clusters and cords of atypical oval cells having moderate amount of cytoplasm and hyperchromatic nucleus. stroma shows scattered lymphomononuclear cell infiltrates.,right breast biopsy :invasive carcinoma nst grade 2. modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 3mitotic figures : 2 6 9 .........
MR1818861,right breast lump carcinoma breast.,right breast core biopsy.,received 3 grey white linear core measures 0.8 to 1 cm. entire tissue processed.,section studied shows linear cores of fibrous tissue with focus of infiltrating lesion arranged in islands and cords. the cells are oval having moderate amount of cytoplasm.hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma is desmoplastic with areas of hemorrhage.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1818908,carcinoma left breast.,left sentinel lymph nodes:a) blue + hot node.b) hot node.c) left mastectomy.,a) received 5 lymph node.largest measures 2.5x1.5x0.5cm.cut surface grey white involved. entire tissue processed.b) received single lymph node measures 1x0.5x0.5cm. entire tissue processed.c) received in : 10 nbf.procedure : left mastectomy.laterality : left.total dimensions : medial to lateral 20cm superficial to deep 4cm superior to inferior 20cm.skin ellipse : 15x7.5cm.nipple : unremarkable. scar surgical defect : absenttumor : single.tumour size : 3x2.5x2cm. location of tumor : lower inner quadrant to central quadrant.margins of tumor : illdefined.deep margin : 1.5cm.muscle : absent adjacent breast : fibrofatty tissue. axillary tail : absent.,section shows breast parenchyma with invasive tumor arranged as diffuse sheets and nests composed of round to oval cells with high n:c ratio vesicular nucleus conspicuous nucleolus and scant cytoplasm. focal extracellular mucin is seen. nuclear pleomorphism is mild and mitosis are sparse. foci of necrosis and solid type ductal carcinoma in situ are seen.,c) left mastectomy.histological type: invasive ductal carcinoma with focal mucinous carcinoma present.grade: itumor measures maximum dimension 3cminvasive component measures 2.7cmductal carcinoma in situ measures 0.3cmmodified br score is 5 9tubule formation: 3nuclear pleomorphism: 1mitotic figures: 1ductal carcinoma in situ is solid type.lymphovascular invasion is not identified.perineural invasion is not identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: 0 lymph nodes metastasis: 0 (0 0).left sentinel lymph nodes:a) blue + hot node:all the 5 lymph nodes isolated are free of tumor (0 5).b) hot node:1 lymph node isolated and is free of tumor (0 1).pathological stage: pt2 snn0summary:invasive ductal carcinoma with focal mucinous carcinoma present left breast.tumor grade: ilymphnode status: 0 6 (sentinel nodes 0 6).
MR1818933,left breast lump carcinoma breast .,biopsy from left breast lump.,received 5 linear grey white soft tissue bits each measures 0.6 to 1.0cm. entire tissue processed.,sections studied from linear cores of lesional tissue harbors an invasive neoplasm arranged in tubules cords and sheets. the cells have scant cytoplasm and irregular overlapping hyperchromatic nuclei brisk atypical mitosis and eosinophilic prominent nucleoli seen in few cells. stroma is desmoplastic. focal myxoid change. necrosis and scattered inflammatory cells.,left breast lump biopsy :invasive carcinoma nos grade iii.mbr score 8 (3+3+2) 8 9.
MR1818941,carcinoma right breast.,breast wide local excision.,a) received 8 blocks labelled as : 3442 18 b) received 3 blocks labelled as : 3476 18.,section studied from lesional tissue harbors an invasive neoplasm arranged in sheets and syncitial pattern. the cells are highly pleomorphic with scant cytoplasm and overlapping hyperchromatic irregular vascular nuclei. brisk atypical mitosis noted sheets of peritumoral lymphotic response present. stroma shows desmoplasia. few foci shows micropapillary and cribriform pattern of ductal carcinoma in situ.,breast wide local excision invasive carcinoma.of ductal origin nst. grade iiimodified bloom richardson score is (3+2+3) 8 9micro papillary and cribriform pattern ductal carcinoma in situ presentcomedonecrosis seen. perineural invasion absent. tumor measures 1.1cm. in its greatest dimension.four of thirteen nodes isolated lymph nodes (4 13) show metastatic tumor deposits. extra nodal extension present.
MR1818948,right breast lump carcinoma breast.,biopsy from right breast lump.,received 5 grey white linear core measures 0.5 to 1cm. entire tissue processed.,sections show multiple linear cores of fibrofatty tissue harboring an infiltrative lesion arranged in sheets nests clusters and occasional tubules the cells have moderate pale eosinophilic to clear cytoplasm pleomorphic hyperchromatic round to oval nuceli with some showing prominent mitotic nucleoli areas discerned (7 8 10hpf) surrounding stroma is desmoplastic with mild lymphomononuclear infiltrate. focal areas of hemorrhage seen. no lymphovascular perineural invasion seen.,right breast lump biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is (3+2+2) 7 9
MR1818954,right breast lump carcinoma breast.,right breast biopsy.,received 5 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrofatty tissue with an infiltrating cellular lesion arranged in nests and cords. the cells are oval having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma is desmoplastic with moderate dense lymphomononuclear infiltrates.,right breast biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is (3+2+2) 7 9
MR1819024,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion composed of cells arranged in sheets nests and trabecules. the cells have scant cytoplasm pleomorphic hyperchromatic round to oval nuclei with prominent nucleoli. surrounding stroma is desmoplastic with mild lymphomononuclear infiltrate. mitotic figures are disorder (5 6 10hpf) no lymphovascular invasion perineural invasion seen.,left breast lump biopsy.invasion ductal carcinoma grade 2.modified bloom richardson score is (2+2+2) 6 9
MR1819031,left breast mass carcinoma breast.,left breast lesion.,received grey white linear core measures 1 to 1.5cm. entire tissue processed.,sections show linear cores of breast parenchyma harboring a lesion with cells arranged predominantly in lobular pattern along with cells in sheets and cords. the cells have moderate eosinophilic cytoplasm mildly pleomorphic hyperchromatic nuclei with inconspicuous nucleoli. surrounding stroma shows extensive desmoplasia. occasional mitotic figures are discerned.,left breast lesion biopsy :invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1819071,left breast lump.,left breast lump.,received 4 grey white linear core measures 1 to 1.5cm.entire tissue processed.,left breast lump biopsy. section studied shows linear cores of fibrocollagenous tissue harboring invasive neoplasm arranged in glandular pattern sheets and nests. the lesional cells are round with hyperchromatic nucleus prominent nucleoli. few cells showing intranuclear inclusion. mitotic figures are discerned. areas of necrosis noted.,left breast lump biopsy :invasive carcinoma nst. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1819084,left breast lump carcinoma breast.,biopsy from left breast lump.,received grey white linear core measures 1 to 1.4cm. entire tissue processed.,section shows cores of fibro adipose tissue harboring in invasive neoplasm in sheets and cords. the neoplastic cells have moderate cytoplasm hyperchromatic nuclei with moderate pleomorphism and increased mitosis. there are areas of hemorrhage and necrosis.,left breast lump biopsy :invasive carcinoma nst grade ii. modified bloom richardson score is (3+2+2) 7 9.
MR1819137,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied from linear cores of lesional tissue invasive carcinoma arranged in tubules nests and scattered isolated cells. the cells have scant to clear cytoplasm and hyperchromatic irregular nuclei. the few ducts are dilated with ductal carcinoma in situ cribriform and comedo type. occasional ducts are showing mild epithelial hyperplasia and calcification. stroma shows desmoplasia with focal myxoid change.,left breast lump biopsy :extensive ductal carcinoma in situ with focus of invasive carcinoma mucinous features grade ii.mbr score (2+2+2) 6 9
MR1819144,multiple liver lesion suggestive of metastasis.,biopsy from liver lesion.,received 4 grey white core measures 1 to 1.5cm. entire tissue processed.,section shows cores of tissue showing sheets and nests of pleomorphic cells in a myxoid hyalinized and focally edemotus stroma. the cells have eosinophilic to clear cytoplasm moderately pleomorphic nuclei. with hyperchromatism. no native liver tissue seen.,biopsy from liver. suggestive of metastatic carcinomatous deposit in a known case of carcinoma breast
MR1819148,case of right breast carcinoma.,a) right breast wide local excision.b) right sentinel lymph node (hot node).c) right sentinel lymph node (blue+hot node).,a) wide local excision specimen measures 8x7x4.5cm.skin ellipse measures 4.5x1.6cm.cut surface shows lesion firm grey white to grey brown 1.8x1.6x1.6cm with irregular margins.distance from the margins:superior margin 2.5cm.inferior margin 1.5cm.medial margin 3cm.lateral margin 2.4cm.deep margin 3.5cm.b) received multiple fibrofatty tissue with 2 lymph nodes altogether measures 3x2x1cm.largest lymph node measures 1.5x1x0.5cm cut surface is fatty infiltration.c) received single lymph node measures 0.5x0.5x0.5cm.,a) section shows tumor infiltrating breast parenchyma compose of tubules nests and cords. the tumor cells are round to oval with marked pleomorphism hyperchromatic nucleus and prominent nucleolus. mitosis are 6 8 hpf. necrosis is seen. solid and cribriform ductal carcinoma in situ is seen with in the lesion. stroma shows desmoplasia and dense peritumoral lymphomononuclear infiltrate.,a) right breast wide local excision:histological type: invasive ductal carcinoma nst .grade 2 tumor measures 1.8cm in maximum dimension.invasive component measures 1.4cm.ductal carcinoma in situ measures 0.4cm.modified bloom richardson score is 7 9.tubular formation 2.nuclear pleomorphism 3.mitotic figures 2lymphovascular invasion is not identified.perineural invasion is not identified.b) right sentinel lymph node (blue node):2 lymph node isolated are free of tumor (0 2).c) right sentinel lymph node (blue+hot node):1 lymph node isolated is free of tumor.pathological stage pt1cpn0.summary:invasive ductal carcinoma nst right breast.tumor grade 2.lymph node 0 3 (sentinel lymph node).
MR1819168,left breast lump carcinoma breast.,biopsy from left breast lump.,received 5 grey white core measures 0.5 to 1.2cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring a lesion with cells arranged predominating in tubules nests and clusters. the cells have moderate eosinophilic cytoplasm pleomorphic hyperchromatic nuclei with prominent nucleoli. mitotic figures are occasional surrounding stroma is desmoplastic. areas of hemorrhage seen.,left breast lump biopsy :invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1819169,left breast lump carcinoma breast.,biopsy from left breast.,received 4 grey white linear core measures 0.5 to 1cm . entire tissue processed.,section studied shows linear cores of fibrous tissue harboring an infiltrating lesion arranged in sheets and nests. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma is desmoplastic with areas of hemorrhage and necrosis perineural invasion is seen.,left breast biopsy :invasion ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1819172,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections studied from linear cores of harbors invasive neoplasm arranged in tubules nests and sheets. the cells are pleomorphic having scant to clear cytoplasm and irregular hyperchromatic nucleus. occasional atypical mitosis seen. stroma is desmoplastic focal myxoid changes with scattered lymphocytic infiltrates and focal area of necrosis.,left breast lump biopsy :invasive carcinoma nos grade ii.mbr score (2+3+2) 7 9.
MR1819194,carcinoma left breast.,a) left breast left breast conservation surgery.b) level 1 amp 2 axillary lymph node dissection.c) level 3 lymph nodes.,a) received wide local excision measures 6.5x6x5cm.skin flap measures 3x1.2cm. cut surface shows grey white forms lesion measures 3x2x2cm.distance from the margins:superior margin 1cm.inferior margin 1.5cm.medial margin 1.5cm.lateral margin 1cm.deep margin 1cm.b) received fibrofatty tissue measures 8x6x4cm. largest lymph node measures 2x1x1cm.c) received fibrofatty tissue measures 3x2x1cm. entire tissue processed.,section from tumor shows cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular or perineural invasion is not seen.,a) left breast left breast conservation surgery:invasive ductal carcinoma grade 2 modified bloom richardson score is 7(3+2+2). tumor measures 3.0 cm in greatest dimension. lymphovascular invasion is not seen. perineural invasion is not seen. all margins of resection are free of tumor.b) level 1 amp 2 axillary lymph node dissection:fifteen lymph nodes are identified negative for malignancy (0 15).c) level 3 lymph nodes:four lymph nodes are identified negative for malignancy (0 4).pathological stage : pt2n0
MR1819196,case of bilateral breast lumpright breast lump neoplastic,biopsy from right breast.,received multiple grey white linear cores measures 1 1.5cm. entire tissue processed.,section reveal linear cores of breast parenchyma harboring invasive tumor in the from of nests and cords composed of polygonal cells with marked pleomorphic hyperchromatic nucleus and moderate eosinophilic cytoplasm. foci of solid pattern of ductal carcinoma in situ is seen. mitosis are sparse . stroma shows dense lymphomononuclear infiltrate and desmoplasia.,biopsy from right breast:invasive carcinoma nst grade 2 with ductal carcinoma in situ.modified bloom richardson score is 7tubule formation:3nuclear pleomorphism :3mitotic activity: 1
MR1819204,left axillary lymph node mets in case of absent breast primary.,a) left axillary dissection. b) revised scar.,a) received fibrofatty tissue measures 7 x 4 x 2 cm. largest lymph node measures 2.5 x 1.2 x 1 cm. cut surface grey white. b) received a revised scar tissue measuring 2.5 x 2 x 1 cm. entire tissue is processed.,a) sections studied shows two out of seventeen lymph nodes shows metastatic deposit of tumor tissue arranged in sheets and nests. the lesional cells are polygonal with moderate eosinophilic cytoplasm round vesicular nuclei and prominent nucleoli. mitotic figures are discerned. no extra nodal extension is seen. b) section shows fibroadipose tissue small aggregates of mononuclear cells congested blood vessels. no evidence of malignancy.,a) left axillary lymph node dissection : metastatic deposits of invasive carcinoma identified in two out of seventeen lymph nodes(2 17). size of the larger tumor deposit of measures 1.5cm in grated dimension. extranodal extension is not identified. b) revised scar : free of tumor.
MR1819217,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear core measures 1.5 to 1.8cm. entire tissue processed.,sections show linear cores of breast parenchyma harboring a lesion with cells arranged in nests clusters and in cords. the cells have moderate eosinophilic cytoplasm round to oval hyperchromatic pleomorphic nuclei with inconspicuous nucleoli. occasional mitotic figures are discerned. surrounding stroma sis desmoplasia with mild lymphomononuclear infiltrate.,biopsy from right breast lump. invasive carcinoma nst grade 2.modified bloom richardson score is (3+2+1) 6 9.
MR1819232,left breast lump carcinoma breast .,left breast lump biopsy.,received 5 grey white linear core measures 0.8 to 1cm. entire tissue processed.,linear core of breast tissue harboring a neoplasm arranged as cords and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is elastotic.,left breast lump biopsy :invasive carcinoma nst grade 2. modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1819315,right breast lump carcinoma breast.,biopsy from right breast.,received 4 grey white liner cores measures 0.3 to 2cm. entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged in cords and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclear conspicuous nucleoli and moderate cytoplasm. the intervening stroma is elastotic.,biopsy from right breast :invasive carcinoma nst grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1819336,right breast lump carcinoma breast.,right breast lump biopsy.,received 4 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,sections show linear cores of breast parenchyma harboring an infiltrative lesion with cells arranged in clusters nests and vague trabecular pattern. the cells have moderate eosinophilic to clear cytoplasm pleomorphic round to oval hyperchromatic nuclei with many having prominent nucleoli. mitotic figures are discerned. surrounding stroma is desmoplastic. areas of calcification are seen.,right breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is (3+2+1) 6 9
MR1819337,left breast lump carcinoma breast.,biopsy from left breast.,received 4 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,sections show linear cores of fibrous tissue fragments harboring an infiltrative lesion with cells arranged in nests clusters and sheets. the cells have moderate pale eosinophilic cytoplasm round to oval pleomorphic nuclei. mitotic figures are discerned. surrounding stroma is desmoplastic.,left breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is (3+2+1) 6 9.
MR1819347,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section studied linear cores of breast parenchyma harboring invasive neoplasm arranged in glandular trabecular nests. the lesional cells are round with moderate amount of eosinophilic cytoplasm round marked pleomorphic hyperchromatic nuclei inconspicuous nucleoli. periductal hyalinization is seen. stroma is desmoplastic and shows myxoid changes and lymphoplasmacytic infiltrates.,right breast lump :invasive carcinoma ductal origin nst grade ii.modified bloom richardson score is (3+3+1) 7 9
MR1819353,right breast lump carcinoma breast.,biopsy from right breast lump.,received five grey white linear core measures 1 to 1.5 cm. entire tissue processed.,sections show linear cores of breast parenchyma harboring an infiltrative lesion with cells arranged in sheets nests and clusters. the cells have moderate eosinophilic to clear cytoplasm pleomorphic round to oval hyperchromatic nuclei with prominent nucleoli. mitotic figures are discerned. surrounding stroma is desmoplastic with moderate lymphomononuclear infiltrates. focal areas show ductal carcinoma in situ comedo and solid pattern. intermediate grade. areas of necrosis seen.,right breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2). ductal carcinoma in situ (comedo solid) intermediate grade noted.
MR1819381,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows cores of breast tissue harboring an cribriform tubules invasive neoplasm in nests find sheets. the cells show abundant cytoplasm moderately pleomorphic vesicular nuclei and predominant nucleoli. stroma is desmoplastic. few cells shows foamy and clear cytoplasm.,biopsy from left breast lump. invasive carcinoma nst grade ii. modified bloom richardson score is (2+3+2) 7 9
MR1819407,multiple enlarged left axillary node metastatic nodes.,biopsy from left axillary nodal mass.,received grey multiple 6 linear cores measures 1x1.5cm. entire tissue processed.,the section show linear cores of tissue showing tumor cells infiltrating in sheets cords and nests. the tumor cells are round to ovoid with increased n:c ratio enlarged ovoid hyperchromatic nuclei and moderate tumor cells have eccentric nuclei and show pale vacuolated cytoplasm. interspersed stroma is desmoplastic peripherally scant lymphoid infiltrate and fibroadipose tissue is noted.,biopsy from left axillary nodal mass.metastatic carcinoma primary in the breast. suggest ihc.
MR1819464,left breast lump carcinoma breast.,biopsy from left breast lump.,received 3 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows cores of breast parenchyma harboring an invasive neoplasm in sheets and cords. the cells show moderate to abundant cytoplasm pleomorphic hyperchromatic nuclei and prominent nucleoli. there is dense intra and peritumaral lymphoplasmacytic infiltrate.,left breast lump biopsy :invasive carcinoma nst grade iii. modified bloom richardson score is (3+3+2) 8 9
MR1819512,right breast lump carcinoma breast.,biopsy from right breast lump.,received grey white linear core measures 1 to 1.5cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in nests and trabeculae. the cells show moderate cytoplasm round to oval hyperchromatic eccentric nuclei with moderate pleomorphism. stroma is desmoplastic. areas show solid type low grade ductal carcinoma in situ.,right breast lump.invasive carcinoma nst.grade ii. modified bloom richardson score is (3+2+1) 6 9
MR1819514,right breast lesion carcinoma breast.,biopsy from right breast lump.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm composed of cords and nests of pleomorphic cells with moderate cytopalsm round hyperchromatic nuceli. there is brisk mitosis with areas of necrosis.,right breast biopsy :invasive carcinoma nst grade iii.modified bloom richardson score is (3+2+3) 8 9
MR1819528,right breast lump carcinoma breast.,biopsy from right breast lump.,received 3 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section cores of breast tissue harboring an invasive neoplasm composed nests and cords of pleomorphic cells with moderate cytoplasm pleomorphic hyperchromatic nuclei and prominent nucleoli.,right breast biopsy :invasive carcinoma nst grade iii. modified bloom richardson score is (3+2+3) 8 9
MR1819532,lump left breast.,left breast lump wedge biopsy.,received skin covered soft tissue bits measures 2x1x1cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump wedge biopsy : invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1819539,case of left breast carcinoma.,left modified radical mastectomy post lumpectomy.,received in : formalin.procedure : left modified radical mastectomy post lumpectomy.laterality : left.total dimensions : medial to lateral 15cm. superficial to deep 6cm. superior to inferior 15cm.skin ellipse : 14x11cm.nipple : retracted.surgical defect : lower outer quadrant measures 4cm in length. lumpectomy defect noted in lower outer quadrant with grey white areas 2.5x1.3x1cm. area around the defect shows grey white lesion.tumor 2 ( 1 o clock) measures 1x0.5x0.5cm.distance between the 2 lesion is 3.2cm.tumor : multiple margins of tumor : illdefined (tumor 1 amp 2). deep margin : tumor 1 3 tumor 2 2cm.adjacent breast : fibrofatty tissue.axillary tail : 13x6x2.5cm.size of largest node : 2.2x1.2x1cm. cut surface is fatty infiltrated.,sections show breast parenchyma with residual invasive lesion arranged in indian file pattern and sheets. the sheets are round to oval having hyperchromatic nuclei and moderate cytoplasm. also cells with eccentrically placed nuclei vacuolated cytoplasm. lobular carcinoma in situ present. intervening stroma shows lymphocytic infiltrate. adjacent areas shows foreign body type giant cells sheets of histiocytes.,left modified radical mastectomy post lumpectomy:histological type: invasive carcinoma with lobular features.nuclear grade: 2tumor measures maximum dimension 1cmnuclear pleomorphism: 2lobular carcinoma in situ is present.lymphovascular invasion is indeterminate.perineural invasion is not identified.posterior resection margin is free of tumor.nipple and areola is free of tumor.lymph nodes: 14 lymph nodes metastasis: 1 (1 14).size of metastatic deposit is 0.2cm.no extranodal spread is seen.summary:invasive carcinoma with lobular features.nuclear grade : 2lymphnode status: 1 14
MR1819556,carcinoma left breast.,a) left breast lump left breast conservative surgery.b) blue + hot node.c) hot node.,a) received single fibrofatty tissue measures 9.5x6.5x6cm. cut surface shows grey white lesion measures 2.5x2.5x2cm. distance from the margin:superior margin 1.5cm.inferior margin 2cm.medial margin 3cm.lateral margin 1.5cm.deep margin 3cm.b) received single fibrofatty tissue measures 3x1.5x1cm.single lymph node isolated measures 1.5x1x1cm.cut surface is deposits seen.c) received single fibrofatty tissue measures 1.5x1x1cm.single lymph node measures 1x0.8x0.8cm.cut surface is fatty infiltrate.,sections show breast parenchyma harboring an infiltrative lesion with cells arranged in tubules cribriform pattern cords and trabeculae. the cells have moderate eosinophilic cytoplasm with some having clear cytoplasm hyperchroamtic to vesicular nuclei with prominent nucleoli. atypical mitotic figures are discerned. surrounding stroma is desmoplastic.,a) left breast lump left breast conservative surgery:invasive ductal carcinoma grade ii.tumor measures 2.5cm in greatest dimension.invasive carcinoma is 2.5cm.ductal carcinoma in situ is not identified.modified bloom richardson score 6 9.tubular formation 2.nuclear pleomorphism 2.mitotic activity 2. 6 9 no lymphovascular invasion perineural invasion seen.b) blue + hot node:one lymph node isolated free of tumor (0 1).c) hot node:one lymph node isolated free of tumor (0 1).pathological grade : pt2pn0.
MR1819565,left breast lobulated mass carcinoma breast.,biopsy from left breast.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,left breast lump biopsy. section shows linear cores of breast parenchyma with occasional foci of cells in nests and clusters. rest of the areas show extensive ductal carcinoma in situ of solid and cribriform pattern. stroma shows myxoid change with desmoplasia and mild lymphomononuclear infiltrates.,biopsy from left breast : extensive areas of ductal carcinoma in situ of solid and cribriform pattern with intermediate nuclear grade are seen. small foci of invasion is also seen.
MR1819590,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 1.5 to 2cm. entire tissue processed.,sections studied shows linear cores of breast parenchyma harboring an infiltrative lesion with cells arranged in nests clusters cords and trabecular. the cells have scant to moderate cytoplasm pleomorphic hyperchromatic nuclei with inconspicuous nucleoli. mitotic figures are discerned. surrounding stroma is desmoplastic with moderate lymphomononuclear infiltrates.,right breast lump core biopsy :invasive ductal carcinoma grade2. modified bloom richardson score is 7(3+2+2).
MR1819635,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple grey white lined cores measures 1 to 1.5cm. entire tissue processed.,sections show linear cores of breast parenchyma harboring a lesion with cells in nests and clusters. the cells have round cytoplasm round to oval mildly pleomorphic hyperchromatic nuceli. adjacent area shows extracellular mucin pools. surrounding stroma is desmoplastic. mitotic figures are few. rest of the areas show ductal carcinoma in situ in solid and cribriform pattern with low nuclear grade.,left breast lump biopsy :invasive carcinoma with mucinous component grade 2 with dcismodified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........ductal carcinoma in situ (solid cribriform) low nuclear grade is noted.
MR1819669,left breast lesion.,biopsy from left breast lesion.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied show linear core of breast parenchyma harboring neoplasm arranged in nest cords and trabeculae and inconspicuous nucleoli moderate amount of eosinophilic cytopalsm. stroma show desmoplastic and myxoid change. mitotic figures also discerned. lymphomonocytic infiltrates also seen.,left breast lesion. invasive carcinoma ductal origin (nst) grade ii. mbr score is (3+2+1) 6 9.
MR1819674,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple grey white to soft tissue bits linear core measures 0.5 to 1.2cm entire tissue processed.,sections show linear cores of breast parenchyma harboring an infiltrative lesion with cells arranged in sheets. the cells have moderate eosinophilic to vacuolated cytoplasm pleomorphic round to oval hyperchromatic nuclei with few having prominent nucleoli. mitotic figures are discerned. surrounding stroma is desmoplastic. wide areas of necrosis noted extensive ductal carcinoma in situ seen.,left breast lump biopsy. invasive carcinoma nst grade 2.modified bloom richardson tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........extensive ductal carcinoma in situ seen. (solid).
MR1819680,carcinoma left breast.,left modified radical mastectomy post lumpectomy.,received in : 10 nbf.procedure : left modified radical mastectomy post lumpectomy.laterality : left.total dimensions : medial to lateral 18cm. superficial to deep 4.5cm. superior to inferior 16cm.skin ellipse : 12x9cm. nipple : normal scar surgical defect : 12 o clock.tumor : single. defect measures 3x2.5x1.5cm wall of defect small grey white well nodule measures 0.5x0.5x0.5cm.deep margin : 1cm.muscle : absent axillary tail : 9x6x4cm.size of largest node : 19x1.5x1.0cm.,sections show breast parenchyma harboring an infiltrative lesions with cells in sheets and cords. the cells have moderate amount cytoplasm pleomorphic hyperchromatic nuclei with prominent nucleoli. atypical mitotic figures (1 2 hpf). surrounding areas show multinucleate giant cells.,left modified radical mastectomy post lumpectomy:histological type: residual invasive carcinoma nst.grade: iiitumor measures maximum dimension 0.5cminvasive component measures 0.5cmmodified br score is 8 9tubule formation: 3nuclear pleomorphism: 2mitotic figures: 3lymphovascular invasion is present.perineural invasion is absent.posterior resection margin is free of tumor.nipple and areola is free of tumor.lymph nodes: 13 lymph nodes metastasis: 5 (5 13).extranodal extension seen.pathological stage: ypt1an2summary:residual invasive carcinoma nst.tumor grade: iiilymphnode status: 5 13 with extranodal extension.
MR1819693,left breast lump carcinoma breast.,biopsy from left breast lump.,received grey white 4 linear cores measures 1 to 1.5cm. entire tissue processed.,cores of breast parenchyma harboring an invasive neoplasm in cords and nests in a desmoplastic stroma. the neoplastic cells have moderate cytoplasm pleomorphic hyperchromatic nuclei and increased mitosis.,biopsy from left breast lump :invasive carcinoma nst.mbr score is (3+2+2) 7 9. grade ii.
MR1819713,case of right breast carcinoma.,a) right sentinel lymph node biopsy.b) right mastectomy post lumpectomy.c) right axillary dissection.,a) received 2 lymph node.largest measures 1x0.8x0.5cm.smallest measures 0.6x0.3x0.3cm. entire tissue processed.b) received in : 10 nbf.procedure : right mastectomy.laterality : right.total dimensions : medial to lateral 14cm. superficial to deep 3cm. superior to inferior 12cm.skin ellipse : 12x7cm.nipple : normal scar 9 o clock : 2x0.5cm.no obvious tumor identified.location of tumor bed 9 o clock : grey white areas m s 2.5x2x1.5cm. deep margin : 0.6 cm.c) received fibrofatty tissue measures 7x2x2cm.largest lymph node measures 1.8x1.5x1cm.cut surface fatty infiltration.,sections show breast parenchyma harboring an infiltrative lesion with cells in sheets having scant cytoplasm pleomorphic hyperchromatic to vesicular nuclei with prominent nucleoli. atypical mitosis discerned (1 2 10 hpf). stroma is desmoplastic with moderate lymphomononuclear infiltrate.,right mastectomy post lumpectomy.histological type: residual invasive ductal carcinoma.grade: ii.tumor measures maximum dimension 0.6cminvasive component measures 0.6cm.modified br score is 7 9tubule formation: 3nuclear pleomorphism: 2mitotic figures: 2ductal carcinoma in situ is absent.lymphovascular invasion is present.perineural invasion is absent.posterior resection margin is free of tumor.nipple and areola is free of tumor.lymph nodes: 18 lymph nodes metastasis: 1 (1 18).pathological stage: ypt1n1.summary:residual invasive ductal carcinoma right breast (post lumpectomy).tumor grade: iilymphnode status: 1 18.one of two sentinel nodes shows metastasis (frozen). extranodal extension seen.right axillary clearance : sixteen nodes isolated all are free of tumor.
MR1819731,right retroareolar lesion carcinoma.,biopsy from right breast lesion.,received grey white 4 linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in cords. the cells show increased n:c ratio moderately pleomorphic nuclei with coarse chromatin and irregular nuclear membrane.,right breast biopsy :invasive carcinoma nst grade ii. mbr score is (3+2+2) 7 9.
MR1819743,right breast lesion.,biopsy from right breast lesion.,received multiple grey white 4 linear cores measures 1.1 to 1.5cm. entire tissue tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring an invasive neoplasm arranged in glandular pattern pattern trabecular cords. the lesional cells round scant to moderate eosinophilic cytopalsm round to ovoid hyperchromatic nucleus. mitotic figures are discerned. stroma shows desmoplasia and mild inflammatory infiltrate.,biopsy right breast mass.invasive ductal carcinoma nst.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 .........
MR1819762,left breast lump.,left breast lump.,received grey white 4 linear core measures 1 to 1.5cm. entire tissue processed.,sections show linear cores of breast parenchyma harboring an infiltrative lesion with cells arranged in nests clusters cords trabecular and vague acinar pattern. the cells a have scant cytoplasm pleomorphism hyperchromatic nuceli with prominent nucleoli. mitotic figures are discerned. surrounding stroma is desmoplastic with lymphomononuclear infiltration.,left breast lump. invasive duct carcinoma grade 2.modified bloom richardson score is (3+2+2) 7 9
MR1819765,carcinoma right breast.,right mastectomy.,received 2 unlabelled container.a container single soft tissue bits measures 0.5x0.5x0.5cm. entire tissue processed.b container received single soft tissue bits measures 1x0.8x0.5cm.c) received in : 10 nbf.procedure : right mastectomy.laterality : right.total dimensions : medial to lateral 18cm. superficial to deep 4cm. superior to inferior 13cm.skin ellipse : 12x6cm.nipple : normal tumor : single. cut surface grey white with mucoid areas tumour size : 3x2x0.8cm. location of tumor : 7 o clock. deep margin : 0.8cm.muscle : absent d) received fibrofatty tissue measures 7x6x2cm.,sections show breast parenchyma with extensive areas of extracellular mucin pools with cells arranged in nests and clusters. the cells have scant cytoplasm pleomorphic round to oval hyperchromatic nuclei with prominent nucleoli. atypical mitotic figures are discerned. adjacent ducal carcinoma in situ (solid cribriform) intermediate nuclear grade noted.,right mastectomy:histological type: mucinous carcinoma.grade: ii.tumor measures maximum dimension 3cminvasive component measures 2.2cmductal carcinoma in situ measures 0.8cmmodified br score is 7 9tubule formation: 3nuclear pleomorphism: 2mitotic figures: 2ductal carcinoma in situ is present with cribriform and comedonecrosis.lymphovascular invasion is intermediate.perineural invasion is absent.posterior resection margin is free of tumor.nipple and areola is free of tumor.lymph nodes: sentinel nodes one out of two isolated show metastasis (1 2)axillary clearance fifteen nodes isolated free of tumour (0 15)total one out of seventeen nodes shows metastsis (1 17)pathological stage: pt2n1mx.summary:mucinous carcinoma right breast.tumor grade: 2lymphnode status: 1 17.lymph nodes: sentinel nodes one out of two isolated show metastasis (1 2)axillary clearance fifteen nodes isolated free of tumour (0 15)total one out of seventeen nodes shows metastsis (1 17)no extranodal extension.
MR1819780,right breast lump carcinoma breast.,biopsy from right breast.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied show linear cores of breast parenchyma harboring an infiltrating lesion arranged in islands cords and singly scattered. the cells are ovoid having moderate amount of cytoplasm pleomorphic hyperchromatic nucleus and prominent nucleoli in few. stroma is desmoplastic with moderately dense lymphomononuclear infiltrates.,biopsy from right breast:invasive ductal carcinoma nst grade 2. modified bloom richardson score is 7(3+2+2).
MR1819792,right breast lump.,biopsy from right breast lump.,received grey white 4 linear cores measures 1 to 1.5cm. entire tissue processed.,right breast lesion biopsy :section studied shows linear cores of breast parenchyma harboring an invasive neoplasm arranged in glandular pattern trabecular. the lesional cells polygonal with moderate eosinophilic cytoplasm round hyperchromatic nucleus some showing prominent nucleoli. mitotic figures are 6 3 10hpf with atypical forms. areas of necrosis and hemorrhage noted.,right breast lesion biopsy :invasive carcinoma nst.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1819809,right breast lump suggestive of breast.,right breast lump.,received grey white multiple 4 linear cores measures 1 to 1.5cm. entire tissue processed.,section show linear cores of breast parenchyma harboring an infiltrative lesion with cells arranged predominantly in tubules nests and cords. the cells have scant cytoplasm round to oval hyperchromatic nucleoli. mitotic figures are few. surrounding stroma is desmoplastic.,right breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1819845,carcinoma right breast.,right modified radical mastectomy.,received in : 10 nbf.procedure : right modified radical mastectomy.laterality : right.total dimensions : medial to lateral 18cm. superficial to deep 5cm. superior to inferior 15cm.skin ellipse : 10x6cm. nipple : normal scar surgical defect : not seen.tumor : single.tumour size : 2.2x1.6x1.5cm.location of tumor : upper inner quadrant.margins of tumor : illdefined. deep margin : 0.3cm.muscle : absent adjacent breast : fibrofatty tissue. axillary tail : 9x4x2.5cm.size of largest node : 1.2x0.6x0.4cm. cut surface fatty infiltration.,sections from breast parenchyma show extensive areas of ductal carcinoma in situ (solid comedo type) of intermediate nuclear grade with few scattered foci of invasive carcinoma. areas of calcification noted. section from nipple areola show intraductal papilloma.,right modified radical mastectomy.histological type: extensive ductal carcinoma in situ with few foci of invasive carcinoma.tumor measures maximum dimension 2.2cminvasive component measures 0.6 cmductal carcinoma in situ measures 1.6 cmductal carcinoma in situ is present.lymphovascular invasion is absent.perineural invasion is absent.posterior resection margin is free of tumor.nipple and areola is free of tumor.lymph nodes: 11 lymph nodes metastasis: 0 (0 11).pathological stage: pt1n0summary:extensive ductal carcinoma in situ with few foci of invasive carcinoma right breast.lymphnode status: 0 11
MR1819877,right breast mass. carcinoma breast.,biopsy from right breast mass.,received multiple grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section shows multiple cores of breast parenchyma with an infiltrating lesion arranged in diffuse sheets and nests. the lesional cells show moderate nuclear pleomorphism hyperchromatic nuclei and moderate eosinophilic to vacuolated cytoplasm. frequent mitotic figures noted. areas of necrosis are seen.,biopsy from right breast mass:invasive ductal carcinoma grade 3.modified bloom richardson score is 8 9 (3+2+3).
MR1819912,left breast lump carcinoma breast.,biopsy from left breast lump.,received 3 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple fragmented cores of breast parenchyma with a lesion arranged in sheets nests and cords. the lesional cells show moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. few cells show prominent eosinophilic nucleoli. brisk mitotic activity is noted. atypical mitotic figures are noted. areas of necrosis are seen. areas of calcification are seen. perineural invasion is noted. intervening stroma shows desmoplasia and lymphocytic iinfiltrates.,biopsy from left breast lump:invasive ductal carcinoma grade 3.modified bloom richardson score is 8 9 (3+2+3).
MR1819940,carcinoma left breast post nact.,left modified radical mastectomy post nact.,received in : formalinprocedure : modified radical mastectomy laterality : lefttotal dimensions :medial to lateral : 18cm superficial to deep :14cm superior to inferior:5cmskin ellipse : 15.5x9cm nipple : normal scar surgical defect : absenttumor : no tumor identifidmuscle : absentadjacent breast :fibrofatty tissue axillary tail :14x10x3cmsize of largest node :3x2x1.5cm,section studied from breast parenchyma shows only post treatment changes with dense sclerosis and compressed benign ducts. no atypical cells seen.,left modified radical mastectomy post nact:histological type: no residual viable tumor present.nipple and areola is unremarkable.lymph nodes 7 lymph nodes metastasis 0(0 7)pathological stage : ypt0n0summary:no residual viable tumor left modified radical mastectomy.lymph node status: 0 7.
MR1819944,left breast multicentric lesion,biopsy from left breast 4 clock lesion.,received 4 grey white linear cores measures 1.5 2cm. entire tissue processed.,section sows linear cores of breast parenchyma harboring tumor infiltrating as cords and small nests of polygonal cells with high n c ratio hyperchromatic pleomorphic nucleus and scant cytoplasm. mitosis are discerned. stroma shows marked desmoplasia and lymphomononuclear infiltrate.,biopsy from left breast 4 clock position:invasive carcinoma grade 3modified bloom richardson score is 8tubule formation:3nuclear pleomorphism :3mitotic activity: 2
MR1819967,left breast lump carcinoma breast.,biopsy from left breast lump.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets nests. the lesional cells are round to oval with moderate cytoplasm. few cells show prominent nucleoli. the cells exhibit marked nuclear pleomorphism. intervening stroma shows lymphocytic infiltrate. extensive necrosis seen. mitosis 8 10 hpf.,left breast biopsy :invasive carcinoma nst grade 3. mbr score is (3+3+2) 8 9
MR1819981,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of fibroadipose tissue harboring an invasive neoplasm in sheets and cords composed of neoplastic cells with moderate to abundant cytoplasm hyperchromatic round nuclei and prominent nucleoli. stroma is desmoplastic.,biopsy from left breast lump:invasive carcinoma nst.modified bloom richardson score is 3+2+2 7 9.grade ii.
MR1820021,left breast mass.,biopsy from left breast mass.,received grey white 5 linear cores measures 1 to 1.5cm. entire tissue processed.,cores of tissue harboring an invasive neoplasm in sheets and thick ribbons. the cells show moderate cytoplasm ill defined cell borders large pleomorphic nuclei with prominent eosinophilic nucleoli. there is dense lymphoplasmacytic infiltrate in the peritumoral areas.,biopsy from left breast mass :invasive carcinoma (nst) mbr score is (3+3+2) 8 9grade iii.
MR1820036,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,cores of breast tissue harboring an invasive neoplasm in nests and cords and tubules. the tumor cells show moderate cytoplasm pleomorphic hyperchromatic nucleoli. stroma is desmoplastic.,biopsy from right breast lump :invasive carcinoma (nst)mbr score is (3+3+2) 8 9grade ii.
MR1820037,left breast lump carcinoma breast.,left breast lump biopsy.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of breast tissue harboring are invasive neoplasm in nests cords and tubules and hyperchromatic pleomorphic nuclei. the stroma in desmoplastic.,left breast lump biopsy. invasive carcinoma (nst) mbr score is (2+3+2) 7 9. grade ii.
MR1820044,right breast lump carcinoma breast.,biopsy from right breast lump.,received 3 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in sheets. the cells show moderate cytoplasm. moderately pleomorphic nucleoli and prominent nucleoli. stroma is desmoplastic with extensive crush artifact.,right breast lump.invasive carcinoma nst.mbr score is (3+3+2) 8 9grade iii
MR1820105,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.5 to 0.8cm. entire tissue processed.,section shows tiny fragments of tissue composed of sheets of highly pleomorphic cells with moderate cytoplasm round to oval hyperchromatic nuclei. mitosis is brisk foci show lymphocytic aggregates. areas of necrosis seen.,biopsy from left breast lump:invasive carcinoma nst.modified bloom richardson score is 3+2+3 8 9 grade iii.areas of necrosis seen.
MR1820116,left breast cancer.,a) left sentinel directed axillary dissection.b) left breast: wide excision.c) revised base.,a) received 2 lymph nodes largest measures 2.2x1.5x0.5cm. cut surface is fatty infiltration. entire tissue processed.b) received wide local excision measures 8x7x4cm. skin flap measures 7x3cm. cut surface show tumor measuring 3x2.3x2cm.distance from the margin:superior margin 4cm.inferior margin 2cm.medial margin 3cm.lateral margin 3cm.deep margin 0.6cm.c) received fibrofatty tissue measures 1.5x1x0.5cm.inked surface in the deep margin.,sections show breast parenchyma harboring an infiltrative lesion arranged in sheets nests cords and trabecular. the cells have moderate cytoplasm pleomorphic round to oval hyperchromatic nuclei with prominent nucleoli. atypical mitoses are discerned (3 4 10hpf). surrounding stroma is desmoplastic.,a) left sentinel directed axillary dissection:three nodes isolated free of tumor (0 3).b) left breast: wide excision:invasive ductal carcinoma grade ii.modified bloom richardson score is 3+2+2 7 9.tumor measures 3cm in greatest dimension.invasive component 3cm.no ductal carcinoma in situ seen.no lymphovascular invasion perineural invasion seen.all margins (superior inferior medial lateral and deep) are free of tumor.c) revised base:free of tumor.pathological stage : pt2nsn (0)
MR1820117,left breast lump.,biopsy from left breast.,received 4 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section studied show linear core of breast parenchyma harboring infiltrating lesion arranged in tubules cords and trabecular pattern. lesional cells are polygonal with round pleomorphic nuclei some cells are showing intra nuclear inclusion. moderate amount of eosinophilic cytoplasm. adjacent stroma show desmoplastic change and myxoid degeneration along with lymphoplasmacytic infiltration. mitotic figures discerned. foci of ductal carcinoma in situ seen.,left breast lump. suggestive of invasive ductal carcinoma . mbr score is (3+2+1) 6 9. grade ii.
MR1820150,right breast lesion.,right breast lump.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets cords nests the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm cells exhibit moderate nuclear pleomorphism. intervening stroma shows scattered lymphocytic infiltrate. mitosis 6 7 10hpd. necrosis seen.,right breast lump biopsy :invasive ductal carcinoma grade iii.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1820159,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear core measures 1 to 0.5cm. entire tissue processed.,section cores of fibrocollagenous tissue harboring an invasive neopalsm in cords and tubules. the cells show moderate to abundant cytoplasm round to oval hyperchromatic nucleoli with moderate pleomorphism. stroma is desmoplastic.,right breast lump biopsy :invasive carcinoma.mbr score is (3+2+2) 7 9. grade ii.
MR1820192,left breast lump carcinoma breast.,biopsy from left breast lump.,received grey white linear core measures 1 to 1.5cm. entire tissue processed.,cores of fibrocollagenous tissue harboring an invasive neoplasm in sheets and cords. the cells show moderate cytoplasm hyperchromatic nuclei with moderate pleomorphism. stroma is desmoplastic. occasional ducts show solid type ductal carcinoma in situ.,left breast lump biopsy :invasive carcinoma nst.mbr score is (3+2+2) 7 9.grade ii.
MR1820214,right breast retroareolar lesion carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of breast parenchyma showing areas of atypical ductal hyperplasia showing round cells with abundant cytoplasm round hyperchromatic nucleus exhibiting minimal atypia. also seen are foci of ductal carcinoma in situ in solid cribriform pattern showing intermediate to high grade nuclear features. stroma shows hyalinisation with mild inflammatory cells.,biopsy from right breast lump. predominantly atypical ductal hyperplasia with foci of ductal carcinoma in situ (intermediate to high grade).
MR1820230,right breast lump neoplastic.,biopsy from right breast lump.,received grey white multiple linear cores measures 1 to 1.5cm. entire tissue processed.,the sections shows linear cores of tissue exhibiting tumor infiltrating in nests and occasional tubules. the tumor cells are round to ovoid with high n:c ratio ovoid hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. areas of necrosis are seen. intervening stroma is desmoplastic.,biopsy from right breast lump.invasive ductal carcinoma nst grade ii.modified bloom richardson score 7 9.tubular formation 3.nuclear pleomorphism 2mitotic activity 2. 7 9
MR1820237,right breast lesion.,biopsy from right breast lesion.,received 5 grey white linear core measures 0.8 to 1cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1820264,right breast mass.,biopsy from right breast mass.,received 5 grey white linear cores measures 1 to 1.5 cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. pools of extracellular mucin are seen.,right breast mass core biopsy:invasive carcinoma with mucinous features grade 2. modified bloom richardson score is 6(3+2+1).
MR1820274,left breast lump carcinoma breast.,biopsy from left breast lump.,received grey white multiple linear cores measures 0.8 to 1 cm. entire tissue processed.,the sections shows linear cores of tissue exhibiting dense sclerosis and tumor infiltrating in cords and nests. tumor cells are round to ovoid with high n:c ratio enlarged ovoid hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. intervening stroma shows desmoplasia.,biopsy from left breast lump:invasive ductal carcinoma nst grade ii.modified bloom richardson score 6 9.tubular formation 3.nuclear pleomorphism 2mitotic activity 1 6 9
MR1820283,left breast mass carcinoma breast.,biopsy from left breast mass.,received 6 grey white linear cores measures 1 1.5cm. entire tissue processed.,section studied shows multiple linear cores of breast parenchyma .one areas showing infiltrating lesion arranged in small nest trabeculae .lesional cells have round to oval hyperchromatic nuclei inconspicuous nuclei moderate amount of eosinophilic cytoplasm. multiple foci of ductal carcinoma in situ with comedo necrosis also noted. stroma show lymphomononuclear infiltrate and desmoplasia.,biopsy from left breast mass:small focus of invasive carcinoma with ductal carcinoma in situ ( high grade).
MR1820285,carcinoma left breast.,left modified radical mastectomy.,received in : 10 nbf.procedure : left modified radical mastectomy.laterality : left.total dimensions : medial to lateral 16cm. superficial to deep 6.5cm. superior to inferior 14cm.skin ellipse : 11x6cm.nipple : retracted. scar surgical defect : absent tumor : single.tumour size : 4x4x3.5cm. location of tumor : retroareolar central quadrant.margins of tumor : illdefined. deep margin : 3.5cm.muscle : absent adjacent breast : fibrofatty tissue. axillary tail : 10x8x2cm.size of largest node : 1.5x1x0.5cm. cut surface deposit seen.,sections show breast parenchyma harboring an infiltrative lesion with cells arranged in tubules sheets nests and cords. the cells have scant to moderate cytoplasm pleomorphic round to oval nuclei with prominent nucleoli. atypical mitoses are discerned (3 4 10hpf). surrounding stroma is desmoplastic with moderate lymphomononuclear infiltrates.,left modified radical mastectomy.histological type: invasive ductal carcinoma.grade: ii.tumor measures maximum dimension 4cminvasive component measures 4cm.modified br score is 6 9tubule formation: 2nuclear pleomorphism: 2mitotic figures: 2ductal carcinoma in situ is absent.lymphovascular invasion is present.perineural invasion is absent.posterior resection margin is free of tumor.lymph nodes: 17 lymph nodes metastasis: 2 17.no extranodal extension seen.tumor is seen infiltrating the dermis. however the epidermis is free of tumor.pathological stage: pt2n1summary:invasive ductal carcinoma left breast.tumor grade: ii.lymphnode status: 2 17. no extranodal extension.
MR1820287,right breast lump carcinoma breast.,biopsy from right breast lump.,received grey white multiple linear cores measures 1 to 1.5cm. entire tissue processed.,the sections shows linear cores of tissue exhibiting tumor infiltrating in cords and nests. the tumor cells are round to ovoid with high n:c ratio enlarged hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. the intervening stroma is desmoplastic.,biopsy from right breast lump.invasive ductal carcinoma nst grade ii.modified bloom richardson score 6 9.tubular formation 3.nuclear pleomorphism 2mitotic activity 1 6 9
MR1820294,right breast lump carcinoma breast.,biopsy from right breast lump.,received grey white multiple linear cores measures 0.8cm. entire tissue processed.,the sections show linear cores of tissue exhibiting dense sclerosis and tumor infiltrating in the form of irregular tubules. the tubules are lined by atypical cuboidal cells having high n:c ratio ovoid hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. focally cribriform ductal carcinoma in situ is noted.,biopsy from right breast lump:invasive ductal carcinoma nst grade i.modified bloom richardson score 4 9.tubular formation 1.nuclear pleomorphism 2.mitotic activity 1. 4 9
MR1820319,carcinoma right breast.,a) right breast 6 o clock lesion.b) right breast upper outer quadrant primary.c) revised base.d amp e) right sentinel node biopsy.,a) received wide local excision specimen measures 6x5.5x2.5cm.skin flap measures 2.5x1cm cut surface show subcutaneous solid cystic lesion measuring 1.5x1x1cm.with friable material which is pultaceousdistance from the margins:superior margin 1.5cm.inferior margin 3cm.medial margin 3cm.lateral margin 2cm.deep margin 2.5cm.b) received soft tissue bits measures 8x5x4.5cm.skin flap measures 5x8cm.cut surface show grey white tumor with infiltrative margins measures 1.6x1.5x1.2cm.distance from the margin :superior margin 1cm.inferior margin 1cm.medial margin 6cm.lateral margin 0.8cm.deep margin 0.7cm.c) received fibrofatty tissue measures 1.5x1x1cm. d) received 2 lymph nodes largest measures 1.5x1.2x0.8cm other measures 1.5x1x0.5cm. cut surface is fatty infiltration.e) received fibrofatty tissue with 1 lymph node measures 0.4x0.3x0.3cm.,sections show breast parenchyma harboring an infiltrative lesion with cells arranged in sheets cords and trabeculae. cells have moderate amount of cytoplasm pleomorphic hyperchromatic nuclei with prominent nucleoli. atypical mitotic figures are discerned (3 4 10hpf). stroma is desmoplastic with lymphomononuclear infiltrates. foci of ductal carcinoma in situ (solid cribriform comedo type) of intermediate nuclear grade noted.,a) right breast 6 o clock lesion:epidermoid cyst.all margins (superior inferior medial lateral deep) free of tumor.b) right breast upper outer quadrant primary:invasive ductal carcinoma grade ii.tumor measures 1.6cm in greatest dimension.invasive component 1cm.ductal carcinoma in situ measures 0.6cm.modified bloom richardson score is (3+2+2) 7 9.lymphovascular invasion is not identified.perineural invasion is absent.ductal carcinoma in situ (solid comedo cribriform type) intermediate nuclear grade seen.all margins (superior inferior medial lateral deep) free of tumor.c) revised base:free of tumor.d amp e) right sentinel node biopsy:three nodes isolated free of tumor.pathological stage : pt1n0.
MR1820325,left breast lump under evaluation.,a) left breast wide excision. b) revised base stitch away from tumor. c) nipple papilloma. d) revised superior margin.,a) left breast wide excision. received wide excision specimen measures 11x9x5cm. skin flap measures 7x1.5cm. cutsurface well circumscribed grey white from tumor measures 5.5x5x4cm. distance from margins :superior margin: 0.5cminferior margin : 0.5cmmedial margin : 1 cmlateral margin : 2 cmdeep margin : 0.5 cmb) revised base stitch away from tumor. received fibrofatty tissue measures 2.5x2x1cm. stitch surface identified and inked.c) nipple papilloma. received fibrofatty tissue measures 0.5x0.5x0.5cm. entire tissue processed. d) received single fibrofatty tissue measures 3x2x1.5cm. cutsurface unremarkable.,sections studied show breast parenchyma with an infiltrating lesion comprising of atypical ducts and fascicles of spindle cells over chondioid stroma. the atypical glands are lined by ovoid cells having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. the spindle cells have moderate amount of cytoplasm and hyperchromatic elongated nucleus. mitotic figures (5 6 10hpf) are discerned. stroma is desmoplastic with focal chondroid areas.,a) left breast wide excision. meta plastic carcinoma with mesenchymal differentiation (chondromatous areas) grade 2. tumor measures 5.5cm in greatest dimension. tumor is located in upper central quadrant.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........ductal carcinoma in situ is not seen. lymphovascular invasion are not identified. perineural invasion are not identified. all margins (superior medial lateral and deep) are free of tumor. b) revised base : free of tumor. c) nipple papilloma : free of tumor. d) revised superior margin : free of tumor.
MR1820338,right breast mass.,biopsy from right breast mass.,received 4 grey white linear cores measures 1 1.5cm. entire tissue processed.,section studied show linear cores of breast parenchyma harboring infiltrating lesion arranged in tubules nest cords trabeculae. lesional cells have round to oval hyperchromatic nuclei inconspicuous nucleoli moderate amount of eosinophilic cytoplasm. stroma shows lympho mononulcear infiltrates desmoplastic change and myxoid degeneration.,biopsy from right breast mass:invasive carcinoma nst grade ii.tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1820393,right breast mass.,biopsy from right breast.,received 3 grey white linear cores measures 1.3 1.5cm. entire tissue processed.,section studied show linear core of breast parenchyma harboring infiltrating lesion arranged in tubules cords nest and trabeculae.lesional cells have pleomorphic round to oval vesicular to hyperchromatic nuclei. some cells are showing prominent nucleoli moderate amount of eosinophilic cytoplasm.ductal carcinoma in situ foci of comedo necrosis seen. stroma shows desmoplastic change along with mitotic figures discerned.,biopsy from right breast:small focus of invasive carcinoma with ductal carcinoma in situ (high grade)modified bloom richardson score is 6 9. grade 2tubule formation :2nuclear pleomorphism :2mitotic figures : 2 6 9
MR1900006,right breast lump carcinoma breast.,biopsy from right breast lump.,received grey white linear core measures 0.5 to 1.5cm. entire tissue processed.,section shows linear cores of tumor composed of nests and sheets of round to oval cells with marked pleomorphism hyperchromatic nucleus prominent nucleus and clear to eosinophilic cytoplasm. mitotic are 10 12 hpf and necrotic foci are seen. stroma shows desmoplastic.,right breast lump biopsy:invasive carcinoma grade 3. modified bloom richardson score is 9(3+3+3).
MR1900019,carcinoma right breast.,a) right axillary sentinel lymph node biopsy.b) right mastectomy.,a) received fibrofatty tissue measures 4x2x1cm.4 lymph nodes identified.largest measures 1.2x1x0.8cm. entire tissue processed.b) received in : 10 nbf.procedure : right mastectomy.laterality : right.total dimensions : medial to lateral 15cm. superficial to deep 4cm. superior to inferior 14cm.skin ellipse : 12x7.5cm.nipple : normal scar surgical defect : absent.tumor : single.tumour size : 3x2.5x2cm.margins of tumor : illdefined. deep margin : 0.8cm.muscle : present.adjacent breast : fibrofatty tissue. axillary tail : no,sections show breast parenchyma harboring an infiltrative lesion with cells arranged in sheets. the cells have moderate amount of cytoplasm pleomorphic round to oval nuclei with prominent nucleoli. atypical mitoses are discerned (2 3 10hpf). areas of necrosis seen. stroma is desmoplastic. a small focus of ductal carcinoma in situ of low nuclear grade seen (solid type),b) right mastectomy:histological type: invasive ductal carcinoma.grade: ii.tumor measures maximum dimension 3cminvasive component measures 2.8cmductal carcinoma in situ measures 0.2cmmodified br score is 6 9tubule formation: 3nuclear pleomorphism: 2mitotic figures: 1ductal carcinoma in situ is present. low grade.lymphovascular invasion is absent.perineural invasion is absent.posterior resection margin is free of tumor. posterior margin is close (0.8cm) however inked margin is free of tumor.nipple and areola is free of tumor.a) sentinel lymph nodes: 8 lymph nodes metastasis: 0 (0 8).pathological stage: pt2nsn (0).summary:invasive ductal carcinoma right breast.tumor grade: iilymphnode status: sentinel nodes: 8 nodes isolated. all are free of tumor (0 8).
MR1900055,carcinoma right breast.,a) right sentinel lymph nodes.b) right mastectomy.c) revised base.,a) received fibrofatty tissue measures 2x1x0.5cm.3 lymph nodes seen measures 6x0.4cm.b) received in : 10 nbf.procedure : right mastectomy.laterality : right. total dimensions : medial to lateral 10cm. superficial to deep 4cm. superior to inferior 16cm.skin ellipse : 16x10cm. nipple : retracted.scar surgical defect : absent.tumor : single.tumour size : 4x3x2cm. location of tumor : upper outer quadrant.margins of tumor : illdefined. deep margin : 0.4cm.c) received single grey white soft tissue bits measures 1.5x1x0.4cm. entire tissue processed.,sections show breast parenchyma with an infiltrative lesion composed of cells arranged in sheets cords and trabeculae. the cells have scant cytoplasm pleomorphic hyperchromatic nuclei with prominent nucleoli. atypical mitosis discerned (1 2 10hpf). stroma shows extensive areas of fibrosis with sclerosed blood vessels.,a) right sentinel lymph nodes:three nodes isolated free of tumor (0 3).b) right mastectomy:histological type: invasive ductal carcinoma.grade: iitumor measures maximum dimension 4cminvasive component measures 4cmmodified br score is 7 9tubule formation: 3nuclear pleomorphism: 2mitotic figures: 2ductal carcinoma in situ is absent.lymphovascular invasion is absent.perineural invasion is absent.posterior resection margin is free of tumor.nipple and areola is free of tumor.c) revised base:free of tumor.pathological stage: pt2nsn(0).summary:invasive ductal carcinoma right breast.tumor grade: iilymphnode status: 3 sentinel nodes identified free of tumor (0 3).
MR1900059,right breast mass carcinoma breast.,biopsy from right breast mass.,received multiple grey white linear cores measures 1.5 to 2cm. entire tissue processed.,the section shows linear cores of breast parenchyma with tumor cells infiltrating in nests cords and sheets. the tumor cells are round to ovoid with a high n:c ratio enlarged ovoid hyperchromatic nuclei and moderate amount of cytoplasm. intervening stroma is desmoplastic. foci of ductal carcinoma in situ are seen (cribriform and solid type).,biopsy from right breast mass:invasive carcinoma nst grade ii.modified bloom richardson score 7 9.tubular formation 3.nuclear pleomorphism 2.mitotic figures 2. 7 9
MR1900075,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear core measures 1 to 1.2cm. entire tissue processed.,section show linear core of breast parenchyma harboring tumor infiltrating as nests and cords in background of abundant of extracellular mucin. the tumor cells show mild pleomorphism and sparse mitosis is seen. stroma shows desmoplasia.,biopsy from right breast lump :invasive carcinoma with mucinous features grade2. modified bloom richardson score is 6(3+2+1).
MR1900093,left breast lump carcinoma breast.,biopsy from left breast lump.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section show linear cores of breast parenchyma with tumor infiltrating as nests composed of polygonal cells with marked pleomorphism hyperchromatic nucleus and moderate clear to eosinophilic cytoplasm. stroma shows dense lymphomononuclear infiltrate.,biopsy from left breast lump : invasive carcinoma grade 2. modified bloom richardson score is 7(3+3+1).
MR1900101,right breast mass. carcinoma breast.,right breast biopsy.,received multiple grey white linear cores measuring 1 to 1.2cm. entire tissue processed.,the section shows linear cores of tissue exhibiting scant tumor infiltrating in nests cords and occasional tubules. the tumor cells are round to ovoid with a high n:c ratio enlarged ovoid hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. intervening stroma shows prominent desmoplastic reaction.,right breast biopsy:invasive ductal carcinoma nst grade ii.modified bloom richardson score is (6 9).tubular formation 3.nuclear pleomorphism 2.mitotic activity 1. 6 9 note:tumor volume is scant to attempt ihc.suggest repeat biopsy for purpose of ihc.
MR1900267,left breast mass carcinoma breast.,left breast mass core biopsy.,received 4 grey white linear cores measures 1.5 2cm. entire tissue processed.,section show linear cores of tumor composed of round to oval cells arranged as sheets and cords. these cells show moderate pleomorphism hyperchromatic enlarged nucleus and scant cytoplasm. mitosis are 6 8 hpf stroma shows desmoplasia.,left breast mass core biopsy:invasive carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1900274,left breast mass carcinoma breast.,left breast mass biopsy.,received 5 linear cores measures 0.8 to 1cm. entire tissue processed.,section studied show linear cores of breast parenchyma harboring an invasion neoplasm arranged in glandular pattern nests trabecule. the cells are round to polygonal with moderate eosinophilic cytoplasm round moderate eosinophilic cytoplasm round moderately pleomorphic hyperchromatic nucleus. some cells show intranuclear inclusions. stroma shows desmoplasia.,left breast mass biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1900377,right breast lump carcinoma breast.,biopsy from right breast mass.,received 4 grey white linear cores measures 0.5 to 1.5cm. entire tissue processed.,section show linear cores of breast parenchyma harboring tumor infiltrating as cords and trabecular composed of polygonal cells with hyperchromatic pleomorphic nucleus and moderate cytoplasm.,right breast lump biopsy :invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1900397,carcinoma left breast.,a) left breast lumpectomy.b) left modified radical mastectomy.,a) received fibrofatty tissue measures 5.5x5x3cm. (unoriented).cut surface show grey white fibrotic areas measures 2.5x2x1cm.b) received in : 10 nbf.procedure : left modified radical mastectomy.laterality : lefttotal dimensions : medial to lateral 22cm. superficial to deep 8cm. superior to inferior 20cm.skin ellipse : 12x9cm.nipple : retractedscar surgical defect : 3cm.tumor : lumpectomy bed.tumour size : 7x6x5cm. location of tumor : upper outer quadrant. margins of tumor : illdefined. deep margin : 1.5cm.muscle : absent adjacent breast : fibrofatty tissue. axillary tail : 13x10x2.5cm.size of largest node : 2x1.5x1cm. cut surface is grey white.,sections from breast parenchyma show an infiltrative lesion with cells arranged in clusters and nests with some of them suspended in extensive extracellular mucin pools. the cells have scant to moderate cytoplasm pleomorphic hyperchromatic nuclei. atypical mitoses are discerned (3 4 10hpf). mucinous carcinoma represents 70 of tumor. focal areas of invasive carcinoma present and represents 30 of the tumor.,a) left breast lumpectomy.histological type:mucinous carcinoma component 70 and invasive ductal carcinoma 30 of tumor.grade: ii.tumor measures maximum dimension 2.5cminvasive component measures 2.5cmmodified br score is 6 9tubule formation: 3nuclear pleomorphism: 2mitotic figures: 1ductal carcinoma in situ is absent.lymphovascular invasion is present.perineural invasion is absent.b) left modified radical mastectomy.lumpectomy bed is free of tumour.posterior resection margin is free of tumor.nipple and areola is free of tumor.lymph nodes: 17 lymph nodes metastasis: 3 (3 17).extranodal extension seen.pathological stage: pt2n1summary:mucinous carcinoma component 70 and invasive ductal carcinoma 30 of tumor left breast.tumor grade: iilymphnode status: 3 17.extranodal extension seen.
MR1900411,carcinoma right breast,right breast right modified radical mastectomy.,received in : formalinprocedure : modified radical mastectomy laterality : righttotal dimensions : medial to lateral : 16 cm. superficial to deep : 4 cm. superior to inferior : 15 cm.skin ellipse :14 x 7 cm. nipple : retracted tumor : singletumour size : 3 x 2.2 x 1 cm location of tumor : upper outer quadrant. margin of tumor : ill defined. deep margin : 1.5cm.muscle : absentadjacent breast : fibrofatty tissueaxillary tail :12 x 10 x 2 cm. size of largest node : 3.5 x 2.5 x 2 cm. cut surface deposit seen measures 3 x 2.2 x 2 cm. representative section are submitted.,section from breast parenchyma display a lesion arranged in sheets cords and trabecular with occasional tubule formation. the cells have scant cytoplasm pleomorphic vesicular nuclei with prominent nucleoli. atypical mitosis are discerned(1 2 10hpf). intervening stroma shows abundant lymphomononuclear infiltration with desmoplasia and focal areas of calcification. focal areas of ductal carcinoma in situ( solid papillary type) of low nuclear grade noted.,right breast right modified radical mastectomy :invasive ductal carcinoma grade 2 tumor measures 3 cm in greatest dimension. modified bloom richardson score is 6(3+2+1). ductal carcinoma in situ of solid and papillary pattern with low nuclear grade are is seen. lymphovascular invasion is identified. perineural invasion is identified. posterior resection margin is free of tumor. nipple and areola is free of tumor.lymph nodes: one out of seventeen lymph nodes shows metastatic tumor deposit withextranodal extension(1 17). size of the tumor deposit measure 3 cm in greatest dimension.pathological stage: pt2n1a
MR1900417,carcinoma right breast.,right modified radical mastectomy post nact.,received in : formalin fresh procedure : right modified radical mastectomy post nact.laterality : right.total dimensions : medial to lateral 20cm. superficial to deep 7cm. superior to inferior 20cm.skin ellipse : 14x9cm ulcero nodular lesion seen measures 1.5x1.5cm.nipple : normal scar surgical defect : absent tumor : singletumour size : 4x3.5x3.5cm. location of tumor : lower inner quadrant.margins of tumor : illdefined. deep margin : 0.2cm.muscle : 8x4cm.adjacent breast : fibrofatty tissue. axillary tail : 10x8x2cm.size of largest node : 2.5x2x1.5cm. cut surface is deposit seen.,sections show breast parenchyma harboring an infiltrative lesion with cells arranged in sheets cords and trabeculae the cells have moderate cytoplasm round to oval hyperchromatic nuclei with prominent nucleoli. atypical mitosis discerned (3 4 hpf). surrounding stroma is desmoplastic. tumor cells are seen infiltrating skin with ulceration of epidermis and muscle bundles. however posterior resected margin is free of tumor.,right modified radical mastectomy post nact.tumor bed: 4x3.5x3.5cm.histological type:residual invasive ductal carcinoma. the tumor is infiltrating skin with ulceration of epidermis. muscle bundles are also infiltrated by tumor however posterior resected margin is free of tumor.grade: iii.tumor measures maximum dimension 4cminvasive component measures 4cmmodified br score is 8 9tubule formation: 3nuclear pleomorphism: 2mitotic figures: 3ductal carcinoma in situ is absent.lymphovascular invasion is present.perineural invasion is absent.posterior resection margin is free of tumor.nipple and areola is free of tumor.lymph nodes: 8 lymph nodes metastasis: 1 (1 8).extranodal extension seen.pathological stage: ypt4bn1summary:residual invasive ductal carcinoma right breast post nact.tumor infiltrating into epidermis along with ulceration of skin.tumor grade: iiilymphnode status: 1 8 with extranodal extension.
MR1900422,left breast mass carcinoma breast.,biopsy from left breast mass.,received 5 grey white line cores measures 1 to 1.5cm. entire tissue processed.,section show linear cores of breast parenchyma harboring tumor infiltrating as nests composed of polygonal cells with pleomorphic hyperchromatic nucleus and scant eosinophilic cytoplasm. stroma shows desmoplasia.,left breast lesion biopsy. invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1900444,right breast mass carcinoma breast.,right breast mass biopsy.,received 7 grey white linear cores measures 0.5 to 1.5cm. entire tissue processed.,section studied shows linear cores of tumor tissue arranged in glandular pattern trabecular and cords. the lesional cells are round to polygonal with moderate clear to eosinophilic cytoplasm moderately pleomorphic hyperchromatic nucleus. mitotic figures are discerned. stroma shows desmoplasia.,right breast mass biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1900460,right breast mass carcinoma breast.,right breast mass biopsy.,received multiple fragmented grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an invasive neoplasm arranged in sheets nests and vague glandular pattern. the lesional cells round with moderate eosinophilic cytoplasm moderately pleomorphic hyperchromatic nucleus. some showing intranuclear inclusions. stroma shows desmoplasia.,right breast mass biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1900536,carcinoma left breast.,a) left breast left breast conservative surgery.b) left sentinel node.c) revised deep margin.,a) received breast conservative surgery specimen measures 6.5x5.5x3.5cm.skin flap measures 4x1.5cm.cut surface show grey white firm well circumscribed lesion measures 3x2.5x2.5cm.distance from the margins:superior margin 0.7cm.inferior margin 0.6cm.medial margin 0.5cm.lateral margin 1.5cm.deep margin 0.5cm.b) received 2 lymph nodes.largest measures 1.8x1.2x1cm. cut surface show fatty infiltration.other measures 1.5x1x1cm. cut surface show fatty infiltration.c) received fibrofatty tissue measures 2x1.5x0.3cm.stitch surface is inked.,sections show breast parenchyma harboring an infiltrative lesion with cells arranged in sheets. the cells have scant cytoplasm pleomorphic vesicular nuclei with prominent nucleoli. atypical mitoses are discerned (2 3 hpf). areas of necrosis seen.,a) left breast left breast conservative surgery:invasive carcinoma nst grade iii.modified bloom richardson score is (3+3+3) 9 9.tumor measures 3cm in greatest dimension.no ductal carcinoma in situ seen.no lymphovascular invasion or perineural invasion seen.all margins (superior inferior medial lateral deep) free of tumor.b) left sentinel node:three nodes isolated all are free of tumor (0 3).c) revised deep margin:free of tumor.pathological stage : pt2nsn (o).
MR1900552,right breast mass.,biopsy from right breast mass.,received 3 grey white linear cores measures 1m. entire tissue processed.,section studied shows linear cores of tumor tissue arranged in sheets nests. the lesional cells round to polygonal with moderate clear to eosinophilic cytoplasm round hyperchromatic nucleus prominent nucleoli. mitotic figures are 10 12 10hpf with atypical forms. stroma shows desmoplasia and mild inflammatory infiltrates.,biopsy from right breast mass. invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1900570,known case of carcinoma right breast post mrm post chemo+rt.,skin nodule biopsy.,received skin covered soft tissue bits measures 1.4x0.5x0.3cm. entire tissue processed.,section shows skin with tumor infiltrating dermis in the form of nests and acini composed of round to oval cells with high n:c ratio hyperchromatic pleomorphic nucleus and scant cytoplasm.,skin nodule. invasive carcinoma in a known case of carcinoma breast.
MR1900649,left breast mass carcinoma breast.,biopsy from left breast.,received 3 linear cores measures 0.6 to 0.9cm. entire tissue processed.,the section shows linear cores of breast parenchyma extrabiting tumor infiltrating in nests cords and sheets. the tumor cells are round to ovoid with enlarged ovoid pleomorphic nuclei occasional prominent nucleoli and moderate amount of cytoplasm. mitotic figures and foci of necrosis are seen.,invasive carcinoma nst grade iii.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 .........
MR1900650,right breast mass carcinoma breast.,biopsy from right breast.,received 3 linear cores measures 0.8 to 1cm. entire tissue processed.,section studied shows linear cores of tumor tissue arranged in sheets nests and trabecule. the lesional cells have moderate eosinophilic cytoplasm and round hyperchromatic nuclei. some showing intranuclear inclusion. mitotic figures are discerned. stroma shows desmoplasia and areas of necrosis.,right breast mass biopsy :invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+3+2).
MR1900658,left breast mass.,biopsy from left breast.,received five linear cores measures 0.8x1cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1900662,left breast solid cystic lesion carcinoma breast.,biopsy from left breast solid cystic lesion.,received 8 grey white linear cores measures 0.2 to 0.5cm. entire tissue processed.,section studied show linear cores of breast parenchyma harboring infiltrating lesion arranged in small nest cords trabecular pattern. lesional cells are large polygonal with pleomorphic round to oval hyperchromatic to vesicular nuclei inconspicuous nucleoli some are showing intranuclear inclusion and prominent nucleoli moderate amount of clear to eosinophilic cytoplasm. stroma show desmoplasia neutrophilic infiltrate and area of calcification.,left breast lesion biopsy :invasive carcinoma (nst) grade iimodified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1900698,right breast mass carcinoma breast.,biopsy from right breast.,received 3 linear core measures 0.4 to 0.9cm entire tissue processed.,the section shows linear cores of breast parenchyma exhibiting tumor infiltrating in cores. the tumor cells are round to ovoid having ovoid hyperchromatic nuclei and moderate amount of cytoplasm. intervening dense desmoplastic reaction is noted. large areas of necrosis are seen.,invasive carcinoma with lobular features grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1900702,right breast lesion carcinoma breast.,right breast biopsy.,received 4 linear cores measures 0.8 to 0.9cm. entire tissue processed.,the section shows tumor cores of breast parenchyma with tumor infiltrating in nests cords and are tubules. the tumor cells are round to ovoid with enlarged hyperchromatic nuclei and moderate amount of cytoplasm. intervening stroma is desmoplastic. foci of necrosis are seen.,invasive carcinoma nst grade iimodified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 .........
MR1900726,left breast lesion carcinoma breast.,biopsy from left breast.,received multiple fragmented grey white linear cores measuring 0.2 to 1cm. entire tissue processed.,the section shows linear cores of breast parenchyma exhibiting tumor infiltrating in sheets and nests. the tumor cells are round to ovoid with enlarged ovoid hyperchromatic nuclei and moderate amount of cytoplasm. mitotic figures are seen. intervening stroma is desmoplastic.,biopsy from left breast :invasive carcinoma nst grade 3.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 .........
MR1900731,right breast mass carcinoma breast.,biopsy from right breast mass.,received 4 grey white linear cores measuring 1 to 1.5cm. entire tissue processed.,the section shows linear cores of breast parenchyma exhibiting tumor infiltrating in cords and nests. the tumor cells are round to ovoid with enlarged ovoid hyperchromatic nuclei and moderate amount of cytoplasm. intervening stroma shows dense desmoplasia and lymphomononuclear infiltrate. adjacent breast shows apocrine change.,biopsy from right breast mass :invasive carcinoma nst grade iimodified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1900744,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores measuring 1 to 1.5cm. entire tissue processed.,the section shows linear cores of breast parenchyma exhibiting tumor infiltrating in nests cords sheets and rare tubules. the tumor cells are round to cuboidal with enlarged ovoid pleomorphic nuclei and moderate amount of cytoplasm. intervening stroma shows desmoplasia. apoptosis is seen. cribriform solid and comode type ductal carcinoma in situ is noted. foci of necrosis are seen.,right breast lump core biopsy invasive carcinoma nst grade 2. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1900761,left breast mass carcinoma breast.,biopsy from left breast mass.,received 5 grey white linear cores measuing 0.8 to 1cm. entire tissue processed.,the section shows linear cores of breast parenchyma exhibiting tumor infiltrating in nests and sheets. the tumor cells are round to polygonal with enlarged pleomorphic hyperchromatic nuclei and moderate amount of cytoplasm. intervening stroma shows dense desmoplasia and lymphomononuclear infiltrate.,left breast mass biopsyinvasive carcinoma nst grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1900805,left breast lump.,left breast mass biopsy.,received 5 grey white linear cores measures 0.5 to 0.2cm. entire tissue processed.,section show linear cores of breast parenchyma harboring tumor infiltrating tubules and nests composed of to oval cells with pleomorphic hyperchromatic nucleus and moderate to scant cytoplasm. mitotic activity is discerned. stroma shows desmoplasia and myxoid change.,left breast mass biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(2+3+2).
MR1900810,right breast mass.,biopsy from right breast mass.,received 3 grey white linear cores measuring 1 to 1.5cm. entire tissue processed.,the section shows linear cores of breast parenchyma exhibiting tumor infiltrating in nests cords and cribriform pattern. the tumor cells are round to cuboidal with enlarged pleomorphic nuclei and moderate amount of cytoplasm intervening stroma shows dense desmoplasia.,right breast mass biopsy :invasive carcinoma nst grade ii. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1900839,right breast lump carcinoma breast.,biopsy from right breast mass.,received 4 grey white linear cores measures 0.8 to 1.3cm. entire tissue processed.,section show linear cores of breast parenchyma harboring tumor infiltrating as sheets nests and tubules composed of round to oval cells with pleomorphic hyperchromatic nucleus and scant cytoplasm. mitosis are discerned. stroma shows desmoplasia and lymphomononuclear infiltrate.,right breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1900863,right breast mass carcinoma breast.,biopsy from right breast mass.,received 6 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged in tubules and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is elastotic.,invasive ductal carcinoma.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1900889,right breast mass.carcinoma right breast.,biopsy from right breast mass.,received grey white linear cores measuring 1 to 1.5cm. entire tissue processed.,the section shows linear cores of breast parenchyma exhibiting tumor infiltrating in nests cords and occasional tubules. the tumor cells are round to cuboidal with a high n:c ratio enlarged ovoid nuclei and moderate amount of cytoplasm. intervening stroma shows dense sclerosis. foci of necrosis are seen. comedo type ductal carcinoma in situ is seen.,biopsy from right breast mass:invasive carcinoma nst grade 2.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphic 2mitotic activity 2 7 9
MR1900899,left breast mass carcinoma breast.,biopsy from left breast.,received 4 grey white linear cores measure 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of tumor tissue arranged in glandular pattern nests and trabeculae. the cells are round with moderate eosinophilic cytoplasm and hyperchromatic nuclei. few showing intranuclear inclusions. mitotic figures are 8 10 10hpf. stroma is desmoplastic.,left breast mass :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1900903,right breast lump carcinoma breast.,biopsy from right breast.,received 3 grey white linear cores measures 2cm. entire tissue processed.,section studied show linear core of breast parenchyma harboring lesion arranged in trabecular and small clusters. lesional cells are polygonal with pleomorphic round to oval hyperchromatic nuclei inconspicuous nucleoli moderate amount of eosinophilic cytoplasm. stroma show desmoplasia and lymphatic infiltrate. foci of ductal carcinoma in situ cribriform pattern also noted.,biopsy from right breast :invasive ductal carcinoma (nst) grade iimodified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1900957,left breast mass carcinoma breast.,biopsy from left breast mass,received multiple grey white linear cores measuring 1 to 1.5cm. entire tissue processed.,the section shows linear cores of breast parenchyma exhibiting tumor infiltrating in nests and cords and forming rare tubular structures. the tumor cells are round to ovoid with ovoid hyperchromatic nuclei and moderate amount of cytoplasm. occasional cells show eccentrically placed nuclei and vacuolated cytoplasm. focally tumor cells infiltrate in a targetoid pattern surrounding ducts. intervening stroma is desmoplastic. solid type ductal carcinoma in situ is noted.,biopsy from left breast mass:invasive carcinoma nst grade iimodified bloom richardson score is 6 9tubular formation 3.nuclear pleomorphism 2.mitotic activity 1. 6 9
MR1900958,right breast mass.,right breast lesion.,received 4 grey white linear cores measures 0.5 to 0.2cm. entire tissue processed.,section studied show linear core of breast parenchyma harboring lesion arranged in acinar trabecular and sheets. lesional cells are polygonal with pleomorphic round to oval pleomorphic vesicular nuclei inconspicuous nucleoli moderate amount of eosinophilic cytoplasm. stroma show desmoplasia and lymphocytic infiltrate .foci of ductal carcinoma in situ also noted.,right breast lesion. invasive carcinoma (nst) grade ii.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1900978,right breast mass carcinoma breast.,biopsy from right breast mass.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section show linear core of breast parenchyma harboring tumor infiltrating as diffuse sheets of round to oval cells with hyperchromatic nucleus and scant cytoplasm. there is marked pleomorphism and foci of necrosis.,right breast mass.invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1900996,right breast mass carcinoma breast.,biopsy from right breast mass.,received grey white linear cores measuring 1 to 1.5cm. entire tissue processed.,the section shows linear cores of breast parenchyma exhibiting tumor infiltrating in cords nests and sheets. the tumor cells are round to cuboidal and show enlarged ovoid hyperchromatic nuclei and moderate amount of cytoplasm. intervening stroma is desmoplastic. areas of hemorrhage and necrosis are seen. mitotic figures are seen.,right breast mass :invasive carcinoma nst grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1901017,left breast mass.,biopsy from left breast mass.,received 5 grey white linear cores measuring 0.8 to 1cm. entire tissue processed.,the section show linear cores of breast parenchyma exhibiting dense sclerosis and tumor infiltrating in nests cords and sheets. the tumor cells are round to cuboidal with enlarged ovoid nuclei and moderate amount of cytoplasm. perineural invasion is seen. intervening stroma is desmoplastic and shows myxoid areas. comedo type ductal carcinoma in situ is seen.,left breast mass biopsy :invasive carcinoma nst grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1901064,right breast lump carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measures 0.5 to 2cm. entire tissue processed.,sections show linear cores of breast parenchyma harboring tumor infiltrating as nests composed polygonal cells with marked pleomorphism. these cells show high n:c ratio hyperchromatic nucleus and moderate cytoplasm. mitosis are (1 2 hpf. stroma shows marked desmoplasia.,biopsy from right breast :invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+2+3).
MR1901076,right breast retroareolar mass carcinoma breast.,biopsy from right breast mass.,received 5 grey white linear cores measures 0.5 to 1c. entire tissue processed.,section show multiple linear cores of breast parenchyma harboring infiltrating lesion composing of nests of cells in extracellular pools of mucin. the lesional cells are round to oval with bland nuclei and moderate cytoplasm mild atypia seen. no mitosis seen.,right breast mass biopsy :invasive carcinoma with mucinous features.
MR1901092,left breast mass carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring a lesion arranged in nests sheets and vague acini. the cells are round to oval with hyperchromatic nuclei abundant eosinophilic cytoplasm eccentrically placed nuclei floating in pools of mucin. adjacent fibrocollagenous stroma shows hyalinisation. occasional l mitotic figures seen.,invasive carcinoma with mucinous features. (grade 1 )
MR1901120,left axillary node metastasis.,biopsy from left axillary node.,received 4 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of invasive neoplasm with extensive areas of necrosis. tumor arranged in glandular pattern nests sheets. the cells are polygonal with moderate clear to eosinophilic cytoplasm round hyperchromatic nucleus some cells show intranuclear inclusion. mitotic figures are discerned.,left axillary lymph node.suggestive of metastatic tumour deposit in known case of carcinoma breast.
MR1901146,left breast lump carcinoma breast.,biopsy from left breast lump.,received 5 grey white linear cores measures 1.5 to 1.8cm. entire tissue processed.,sections shows linear cores of breast parenchyma infiltrated by neoplasm arranged in cords and abortive tubules. the cells have round to irregular hyperchromatic nucleus and moderate cytoplasm. mitotic figures is discerned.,left breast lump :invasive carcinoma nst grade iimodified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1901148,right breast mass carcinoma breast.,biopsy from right breast mass.,received multiple grey white linear cores measures 1.5 to 0.2cm. entire tissue processed.,section shows linear cores of tumor arranged as nests tubules and sheets composed of round to oval cells with hyperchromatic eccentric nucleus and vacuolated cytoplasm (signet ring cell). stroma shows desmoplasia.,biopsy from right breast mass:invasive carcinoma with signet ring cell morphology grade 2. modified bloom richardson score is 6(3+2+1)
MR1901174,right breast lump carcinoma breast.,biopsy from right breast lump.,received 6 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion with cells arranged in sheets nests and occasional vague tubules. the cells have scant cytoplasm pleomorphic round to oval hyperchromatic nuclei. atypical mitosis are discerned. (3 4 10hpf). surrounding stroma is desmoplastic foci of ductal carcinoma in situ (solid cribriform comedo type) of intermediate nuclear grade seen.,right breast lump biopsy :invasive carcinoma with lobular features grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1901190,right breast mass carcinoma breast.,biopsy from right breast mass.,received multiple grey white soft tissue bits measures 0.2 to 1cm. entire tissue processed.,section shows fragments of breast parenchyma harboring tumor infiltrating as nests and sheets of polygonal cells with enlarged hyperchromatic nucleus and moderate dense eosinophilic cytoplasm. mitosis are discerned. areas of necrosis seen. stroma shows dense lymphomononuclear infiltrate.,biopsy from right breast mass:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1901192,left breast lump carcinoma breast.,biopsy from left breast.,received 3 grey white linear cores measures 1.5 to 1.8cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors an infiltrative lesion arranged in sheets and islands. the cells are oval have markedly pleomorphic hyperchroamtic nuclei inconspicuous nucleoli and abundant amount of eosinophilic cytoplasm. mitotic activity is discerned. stroma shows desmoplasia lymphoplasmacytic infiltrate. foci of necrosis is seen.,biopsy from left breast:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1901206,left breast lesion.,biopsy from left breast lesion.,received 4 grey white linear cores measures 0.3to 0.5cm. entire tissue processed.,section shows cores of breast parenchyma with an infiltrating lesion arranged as cords nests and tubules. the cells have round to oval hyperchromatic nuclei and moderate cytoplasm. stroma shows extensive hyalinisation.,left breast lesion biopsy :invasion ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1901224,right breast mass carcinoma breast.,biopsy from right breast.,received four grey white linear core measures 1 to 2 cm. entire tissue processed.,sections show linear core of breast parenchyma harboring tumor arranged as sheets and focal tubular pattern. the tumor cells are polygonal with high n:c ratio hyperchromatic pleomorphic nuclei and scant to moderate amount of cytoplasm. mitosis are discerned. stroma shows marked desmoplasia.,right breast lesion biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(2+2+2).
MR1901225,left retroareolar mass carcinoma breast.,retroareolar mass biopsy.,received 4 grey white linear covers measures 0.8 to 1.8 cm. entire tissue processed.,section studied shows cores of breast parenchyma shows few ducts lined by oval to columnar cells have pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm myoepithelium prominent abluminally. stroma shows fibrosis and lymphoplasmacytic infiltrate.,retroareolar mass biopsy :features suggestive of atypical ductal hyperplasia with foci of atypical tubules. suggest excision of lump for further confirmation.
MR1901229,left breast lesion carcinoma breast.,left breast biopsy,received multiple grey white linear cores measures 2 to 2.5cm. entire tissue processed.,section studied show linear core of breast parenchyma harboring lesion arranged in trabeculae cord and sheets. lesional cells are polygonal with pleomorphic round to oval hyperchromatic nuclei inconspicuous nucleoli moderate amount of eosinophilic cytoplasm. stroma show desmoplasia and lymphocytic infiltrate.,left breast biopsy.invasive carcinoma (nst) grade ii.modified bloom richardson score is 6 9tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1901257,left breast mass carcinoma breast.,left breast.,received 3 grey white linear cores measures 0.5 to 7.5cm. entire tissue processed.,linear cores of breast tissue harboring a neoplasm arranged as clusters and sheets. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is elastotic. foci of high grade ductal carcinoma in situ seen.,left breast:invasive ductal carcinoma grade ii modified bloom richardson score is 6 9.tubular formation 3nuclear pleomorphism 2mitotic activity 1 6 9
MR1901268,right breast lump carcinoma breast.,biopsy from right breast lump.,received 3 grey white linear core measures 1.8 to 2cm. entire tissue processed.,the section shows linear cores of breast parenchyma exhibiting tumor infiltrating in nests and sheets. the tumor cells are round to polygonal having a high n:c ratio enlarged pleomorphic hyperchromatic nuclei and moderate amount of cytoplasm. numerous mitotic figures are seen. solid cribriform and comedo type ductal carcinoma in situ is noted.,right breast lump biopsy :invasive carcinoma nst grade 3.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 .........
MR1901296,carcinoma left breast post nact.,a) left breast wide excision post nactb) revised medial margin.c) left axillary dissection,a)fresh tissue received : yeslaterality : left specimen orientation : orientated specimen size : 5.5x5x2.5cm skin : presentskin dimensions : 5x0.5mlesion dimensions :1.2x1x0.5cmdistance of lesion from margins: superior margin :1.5cminferior margin :2.0cmmedial margin :0.1cmlateral margin :3.0cmdeep margin :1.5cm b)received fibrofatty tissue measures 3x1x0.5cmone side inkedb) received fibrofatty tissue measures 7x6x4cmlargest lymph node measures 1x0.5x0.5cm cut surface fatty infiltration seen.,section from the lesion show residual viable invasive neoplasm in sheets composed of pleomorphic cells with vacuolated cytoplasm moderate nuclear atypia and increased mitosis. there is dense lymphohistocytic infiltration in and around the tumor.,a) left breast wide excision post nact:residual invasive ductal carcinoma nst.modified bloom richardson score is 3+2+3 8 9 grade 3.tumor measures 1.2cm in greatest dimension.ductal carcinoma in situ not identified.lymphovascular invasion not identified.perineural invasion not identified.medial margin is close to tumor 0.2cm.all other margins including deep margin are free of tumor.b) revised medial margin: free of tumor.c) left axillary dissection11 nodes isolated are free of tumor (0 11).pathological stage :ypt1n0.
MR1901297,left breast mass carcinoma breast.,left breast mass biopsy,received multiple grey white linear cores measures 0.5 to 1 cm. entire tissue processed.,section studied show linear cores of breast parenchyma harboring lesion arranged in nest cords trabecular pattern. lesional cells are polygonal with round to oval hyperchromatic nuclei inconspicuous nucleoli moderate amount of eosinophilic cytoplasm. stroma show desmoplasia and lymphocytic infiltrate. foci of solid ductal carcinoma in situ seen.,left breast mass biopsy.invasive carcinoma (nst) grade imodified bloom richardson score is 5 9tubular formation 3nuclear pleomorphism 1mitosis 1 5 9
MR1901331,case of carcinoma left breast.,left axillary node swelling.,received fibrofatty tissue measures 4x3x2cm.largest lymph nodes measures 1.3x1x0.5cm.cut surface shows multiple tissue tiny grey white areas deposits.,section from the nodes show extensive areas of fibrosis and foreign body type giant cell reaction. no evidence of viable metastatic deposit in the nodes examined.,left axillary node swelling:7 nodes examined are negative for malignancy ( 0 7).
MR1901346,right breast lump suggestive of carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores of measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring a lesion arranged in cords abortive tubules and clusters composed of cells with pleomorphic hyperchromatic nucleus stroma is desmoplastic with areas of necrosis and hemorrhage. a focus of ductal carcinoma in situ comedo pattern also seen.,right breast lump biopsy :invasive ductal carcinoma grade ii. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1901373,known case of carcinoma left breast high grade ductal carcinoma in situ.right breast suspicious lesion.,right breast biopsy.,received grey white fragmented linear core measuring 0.2 to 1cm.entire tissue processed.,sections show linear cores of fibrous tissue with extensive areas of necrosis admixed with blood and showing infiltration by mixed inflammatory cells few scattered hemosiderin laden macrophages and cholesterol clefts. no evidence of malignancy seen in the section studied.,right breast biopsy: no evidence of malignancy seen in the section studied and received sample.. suggest repeat representative biopsy if clinically deemed necessary.
MR1901392,left breast lump.,biopsy from left breast.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged on linear cords. the cells have moderate hyperchromatic nuclei and moderate cytoplasm.,biopsy from left breast lump :invasive carcinoma nst grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1901429,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white cores measuring 0.5 to 1cm. entire tissue processed.,the section shows linear cores of breast parenchyma exhibiting tumor cells infiltrating in nests sheets and cords. the tumor cells are round to ovoid with enlarged ovoid nuclei and moderate amount of cytoplasm. intervening stroma shows dense sclerosis. areas of necrosis are seen.,biopsy left breast lump:invasive carcinoma nst grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1901449,left breast lump carcinoma breast.,biopsy from left breast.,received 3 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections show linear cores of fibrous tissue fragments harboring an infiltrative lesion composed of cells arranged in cords trabeculae and clusters. the cells have scant cytoplasm pleomorphic hyperchromatic nuclei. surrounding stroma is desmoplastic.,biopsy from left breast:invasive carcinoma nst grade 2.modified bloom richardson score is (3+2+1) 6 9.
MR1901476,right breast lump carcinoma breast.,biopsy from right breast lump.,received five grey white linear cores measures 1 to 1.8 cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in sheets cords and nests. the cells are oval have nodules pleomorphic hyperchromatic nuclei inconspicuous nucleoli and abundant amount of eosinophilic cytoplasm. mitotic activities is discerned. stroma shows desmoplasia. few foci of necrosis and lymphoplasmacytic infiltrate.,right breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1901479,right breast lump carcinoma breast.,biopsy from right breast lump.,received multiple grey white linear cores measures 0.5x1cm. entire tissue processed.,section studied shows linear cores of fibrous tissue with an infiltrating lesion arranged in nests islands with central necrosis. the cells are ovoid having abundant cytoplasm and hyperchromatic pleomorphic nucleus. mitotic figures are discerned. stroma is desmoplastic with areas of hemorrhage and necrosis.,right breast lump biopsy:invasive carcinoma nst grade 2 tubule formation 3nuclear pleomorphism 2mitotic activity 2mbr score 7 9
MR1901525,left breast mass.,left breast mass biopsy.,received multiple grey white linear cores measures 0.8 to 1.5cm. entire tissue processed.,section show cores of breast parenchyma with a lesion arranged in sheets nests and cords. the lesional cells exhibit moderate nuclear pleomorphism hyperchromatic nuclei and moderate eosinophilic cytoplasm. frequent mitotic figures noted. stroma shows desmoplasia and lymphocytic infiltrates.,left breast mass biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1901542,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 0.8 to 1.5cm. entire tissue processed.,sections show linear cores of fibrofatty tissue harboring an infiltrative lesion arranged in sheets cords and trabecular. the cells have scant cytoplasm with some having clear cytoplasm pleomorphic hyperchromatic nuclei. atypical mitosis are discerned (5 6 10hpf) surrounding stroma is desmoplastic with lymphomononuclear infiltrate.,right breast lump biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1901626,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 1 to 2 cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in nests and sheets. the cells are oval have pleomorphic hyperchromatic nuclei inconspicuous nucleoli and abundant eosinophilic cytoplasm. mitotic activities is discerned. stroma shows desmoplastic.,left breast biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1901628,right breast lump carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrating lesion with cells in sheets. the cells have moderate cytoplasm pleomorphic hyperchromatic nuclei with prominent nucleoli in some. atypical mitosis are discerned (1 2 hpf) extensive lymphomononuclear infiltrate seen around the tumor aggregates.,right breast biopsy :invasive carcinoma grade 3.modified bloom richardson score is 9 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 3 9 9 .........
MR1901631,left breast mass.,left breast mass biopsy.,received multiple grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section studied shows linear cores of fibrous tissue with islands and nests of atypical ovoid cells having moderate amount of cytoplasm and hyperchromatic nucleus. mitotic figures are discerned (8 9 10hpf). stroma is desmoplastic with extensive areas of hemorrhage and necrosis.,left breast mass biopsy :poorly differentiated carcinoma with extensive necrosis. suggest ihc.
MR1901640,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion with cells arranged in nests clusters and vague tubules. the cells have scant to moderate cytoplasm pleomorphic hyperchromatic nuclei. atypical mitosis are discerned. surrounding stroma is desmoplastic.,left breast biopsy.invasive ductal carcinoma grade ii.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1901660,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion with cells arranged in cords trabecular and clusters. the cells have scant to moderate pale eosinophilic to clear cytoplasm. atypical mitoses discerned. (2 3 10hpf). surrounding stroma is desmoplastic with moderate lymphomononuclear infiltrate . calcification noted in few areas. foci of ductal carcinoma in situ (solid type) of intermediate nuclear grade seen.,left breast biopsy :invasive carcinoma nst grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1901671,right breast lump carcinoma breast.,biopsy from right breast.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections show linear cores of fibrofatty tissue harboring an infiltrative lesion with cells arranged in sheets cords trabecular and vague tubular pattern. the cells have scant to moderate clear cytoplasm pleomorphic hyperchromatic nuclei. atypical mitoses are discerned (3 4 10hpf). surrounding stroma is desmoplastic. areas of necrosis seen.,biopsy from right breast:invasive ductal carcinoma grade 2.modified bloom richardson score is (3+2+1) 6 9.
MR1901676,right breast lump carcinoma breast.,biopsy from right breast lump.,received five grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in sheets and nests. the cells are oval have pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. mitotic activity is discerned.,right breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1901679,carcinoma breast.,right breast mass biopsy.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in sheets nests and cords. the cells are round to oval having hyperchromatic nuclei moderate cytoplasm cell exhibit marked nuclear pleomorphism. intervening stroma shows desmoplasia with lymphocytic infiltrate. area of necrosis seen. mitosis 6 7 10hpf.,right breast mass biopsy :invasive ductal carcinoma grade 3.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9 .........
MR1901692,right breast mass carcinoma breast.,biopsy from right breast mass.,received grey white linear cores measures 1 to 2cm. entire tissue processed.,section show multiple lined cores of breast parenchyma harboring infiltrating lesion arranged in nests and cords. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism intervening stroma shows desmoplasia myxoid change. mitosis 3 4 10hpf. ductal carcinoma in situ solid and cribriform type seen. fibrocystic change seen.,biopsy from right breast mass :right breast mass biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MR1901693,left breast mass carcinoma breast.,biopsy from left breast.,received multiple fragment cores measures 0.3 to 0.8cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring a lesion arranged predominantly in papillary pattern. the cells have moderate cytoplasm pleomorphic hyperchromatic nuclei. foci of invasion also noted. stroma shows moderate lymphomononuclear infiltrates. ductal carcinoma in situ (cribriform type) of intermediate nuclear grade seen. areas of hemorrhage noted.,biopsy from left breast:suggestive of invasive carcinoma with papillary features.
MR1901695,left breast mass carcinoma breast.,left breast biopsy.,received 4 grey white linear cores measures 0.8 to 1.5cm. entire tissue processed.,section studied shows cores of breast paranchyma with ducts and lobules. ducts are lined by luminal epithelium without atypia and abluminally myoepithelial layer. stroma shows fibrosis. no evidence of malignancy seen.,left breast biopsy :shows benign breast parenchyma.no evidence of malignancy seen.
MR1901733,carcinoma right breast lump.,right sentinel lymph nodes:a) hot node.b) blue + hot node.c) non blue non hot node.d) right mastectomy.,a) received fibrofatty tissue measures 1x1x0.6cm.isolated 1 lymph node measures 0.7x0.5x0.4cm.b) received fibrofatty tissue measures 2.8x1.5x0.8cm.isolated 1 lymph node measures 1.5x1.2x0.8cm.cut surface show fatty infiltration ink noted.c) received fibrofatty tissue measures 1x1x0.3cm.grossly no lymph node identified.d) received in : formalin.procedure : right mastectomy.laterality : right.total dimensions : medial to lateral 15cm. superficial to deep 4cm. superior to inferior 15cm.skin ellipse : 13x9cm. nipple : normal scar surgical defect : not seen.tumor : single.tumor size : 2.3x2x2cm. location of tumor : 2 3 o clock position.margins of tumor : ill defined.deep margin : 1.2cm.muscle : absent adjacent breast : fibrofatty tissue.axillary tail : absent.,a) section studied show one lymph node with normal architecture. no tumor deposits.b) sections studied show one lymph node with normal architecture. no tumor deposits.c) section shows fibrofatty with cautery artifact.d) section from breast shows an invasive neoplasm arranged in a glands cords and nests. the cells have round nucleus dispersed chromatin prominent nucleoli and moderate cytoplasm. ductal carcinoma in situ is also noted (comedo cribriform and solid pattern).,d) right mastectomy:invasive ductal carcinoma grade iitumor measures maximum dimension 2.3cminvasive component measures 1.8cmductal carcinoma in situ measures 0.5cmmodified br score is 6 9tubule formation: 2nuclear pleomorphism: 2mitotic figures: 2ductal carcinoma in situ identified (solid cribriform comedo pattern)lymphovascular invasion is not identitified.perineural invasion is identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.right sentinel lymph nodes:a) hot node:one lymph node isolated negative for malignancy (0 1).b) blue + hot node:one lymph node isolated negative for malignancy (0 1).c) non blue non hot node:only fibrofatty tissue. no lymph node isolated.
MR1901761,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections studied shows cores of breast parenchyma harbors infiltrative lesion arranged in sheets and nests. the cells are large oval have markedly pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. mitotic activities is discerned. stroma shows desmoplasia necrosis and lymphoplasmacytic infiltrate.,right breast biopsy :invasive ductal carcinoma grade 3 modified bloom richardson score is 8(3+3+2).
MR1901776,right breast lump carcinoma breast.,biopsy from right breast lump.,received multiple grey white linear cores measures 1 to 2cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion composed of cells arranged in sheets cords and nests. the cells have moderate pale eosinophilic to vacuolated cytoplasm and pleomorphic hyperchromatic nuclei. atypical mitoses are discerned (1 2 hpf). surrounding stroma is desmoplastic.,biopsy from right breast lump:invasive carcinoma nst grade 3.modified bloom richardson score is (3+2+3) 8 9.
MR1901779,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring invasive neoplasm arranged in glandular pattern trabeculae and nests. the cells are polygonal with moderate eosinophilic cytoplasm moderately pleomorphic hyperchromatic nucleus few showing prominent nucleoli and intranuclear inclusion. stroma is desmoplastic.,biopsy from left breast lump:invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9.tubular formation 3.nuclear pleomorphism 2mitotic activity 2 7 9
MR1901788,right breast lump carcinoma breast.,biopsy from right breast lump.,received multiple fragmented cores measures 0.3x0.2cm. entire tissue processed.,sections show fragmented cores of fibrous tissue with foci of ductal carcinoma in situ (cribriform type) and abundant extracellular mucin with some cell clusters floating in them. the cells have scant cytoplasm and round to oval dark nuclei. no frank invasive foci seen.,biopsy from right breast lump :ductal carcinoma in situ (cribriform type) with abundant extracellular mucin. suggest excision biopsy.
MR1901791,carcinoma right breast.,biopsy from right breast lump.,received 3 grey white linear cores measures 1 to 2cm. entire tissue processed.,sections show linear cores of fibrosis tissue harboring an infiltrative lesion arranged in sheets nests cords and trabeculae. the cells have moderate pale eosinophilic cytoplasm round to oval pleomorphic nuclei. atypical mitosis are seen (1 2 10hpf). surrounding stroma is desmoplastic.,right breast lump biopsy :invasive carcinoma nst grade 2. modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1901803,right axillary node metastasis.,biopsy from right axillary.,received 5 grey white linear cores measures 0.5 x 0.3 cm. entire tissue processed.,section studied shows cores from lymph node harbors infiltrative lesion arranged in sheets and nests. the cells are oval have pleomorphic abundant eosinophilic cytoplasm. stroma shows desmoplasia.,right axillary lymph node biopsy :features suggestive of metastatic deposits in known case of carcinoma breast.
MR1901813,right breast lump carcinoma breast.,right breast lump biopsy.,received 4 linear cores measures 1 to 1.5cm. entire tissue processed.,sections studied from multiple linear cores harbors invasive neoplasm arranged glandular and nests like pattern. the cells are marked pleomorphic with scant eosinophilic cytoplasm and large irregular hyperchromatic nucleoli. occasional tumor giant cells are seen. focally spindle cells arranged in sheets are seen having hyperchromatic irregular nuclei and scant cytoplasm. stroma shows myxoid change. areas of solid ductal carcinoma in situ are also seen.,right breast lump biopsy :invasive carcinoma nst with nuclear grade 3.
MR1901831,left breast retroareloar lesion.,biopsy from left breast lump.,received 4 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section show linear cores of breast tissue showing infiltrating lesion composed of sheets of dysplastic cells invading the desmoplastic stroma. sparse mononuclear infiltrates seen.,left breast biopsy. :invasive carcinoma nst grade iimodified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MR1901841,right breast lump.,right breast mass biopsy.,received more linear core grey white measures 0.1 to 0.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in nests and sheets. the lesional cells are round to oval having hyperchromatic nucleus moderate cytoplasm. the cells exhibit moderate nuclear pleomorphism stroma shows desmoplasia lymphoplasmacytic infiltrate and focal aggregates of foamy macrophages necrosis seen. brisk mitotic activity noted.,right breast mass biopsy. invasive ductal carcinoma grade 3.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 .........
MR1901857,left breast lump carcinoma breast.,biopsy from left breast lump.,received 5 grey white linear cores measures 1to 2cm. entire tissue processed.,section show linear cores of breast parenchyma showing an infiltrative lesion composed of sheets and nests of dysplastic ductal cells showing moderate pleomorphism hyperchromasia prominent nucleoli. the intervening stroma is desmoplastic and show moderate lymphomononuclear infiltrates. an occasional focus shows ductal carcinoma in situ with comedo necrosis.,left breast biopsy. invasive carcinoma nst grade ii.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 foci of ductal carcinoma in situ with comedo necrosis seen.
MR1901863,left breast lesion carcinoma breast.,biopsy from left breast lesion.,received multiple grey white soft tissue bits measures 0.1 to 1.5cm. entire tissue processed.,section studied shows linear cores of breast parenchyma with dilated ducts of varying size. few ducts shows ductal carcinoma in situ in solid cribriform and comedonecrosis pattern. the cells are ovoid having moderate amount of cytoplasm and hyperchromatic nucleus. there is an intact outer myoepithelial layer. stroma is fibrous with focal lymphoid aggregates.,biopsy from left breast lesion :extensive ductal carcinoma in situ solid cribriform and comedonecrosis. the possibility of an adjacent focus of invasion cannot be ruled out. please correlate with clinical and radio logical findings.
MR1901893,right breast lump carcinoma breast.,biopsy from right breast lump.,received 5 linear cores measures 0.4 to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in nests cords. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. the cells exhibit moderate nuclear pleomorphism. stroma shows desmoplasia.,right breast lump biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
MR1901899,right breast lump carcinoma breast.,biopsy from right breast lump.,received multiple grey brown linear cores measures 1 to 1.3cm. entire tissue processed.,section studied shows linear cores of fibrous tissue with an infiltrating lesion arranged in islands and sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic to vesicular. nucleus and prominent nucleoli. mitotic figures are discerned. (7 8 10hpf). stroma is desmoplastic with areas of hemorrhage and necrosis.,right breast biopsy. :invasive carcinoma nst grade 2. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1901912,right breast lung carcinoma breast.,biopsy from right breast.,received 4grey white linear cores measures 1.5 to 2cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion with cells arranged in nests cords and pleomophic round to oval nuclei. stroma is desmoplastic.,right breast biopsy :invasive carcinoma nst grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1901940,known case of carcinoma right breast.,liver biopsy.,received 4 grey white linear cores measures 1.5 2cm. entire tissue processed.,section studied shows liver parenchyma harbours infiltrative lesion arranged in nests and tubules. the cells are oval have pleomorphic hyperchromatic nuclei conspicuous nucleoli and abundant pale eosinophilic cytoplasm. stroma shows area of necrosis and lymphoplasmacytic infiltrate.,liver biopsy:features are suggestive of metastatic carcinoma in a known case of carcinoma right breast.
MR1901944,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 1 to 2cm. entire tissue processed.,sections show linear cores of fibrofatty tissue harboring an infiltrative lesion with cells arranged in tubules cords and trabeculae. the cells have scant to moderate cytoplasm pleomorphic round to oval nuclei. atypical mitoses discerned (1 2 10hpf). stroma is desmoplastic.,biopsy from left breast lump:invasive ductal carcinoma grade 1.modified bloom richardson score is (2+2+1) 5 9
MR1901950,carcinoma right breast.,biopsy from right breast lump.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion with cells arranged in sheets nests and trabeculae. the cells have scant atypical mitosis are discerned. surrounding stroma is desmoplastic. foci of ductal carcinoma in situ (solid and comedo type) of intermediate nuclear grade seen.,biopsy from right breast lump :invasive carcinoma nst grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........foci of ductal carcinoma in situ (solid and comedo type) seen.
MR1901988,case of right breast carcinoma,a)right breast wide local excisionb)hot nodec) blue node+hot node.,a)received skin covered soft tissue bits mass measures 6x5x4.5cmskin ellipse measures 6x2 cmcut surface shows grey white lesion measures 1.5x1x1cm.distance from margins:superior margin :1.1cminferior margin :l2.1cmmedial margin :2cmlateral margin :2.5cmdeep margins :2cm.b) received single node measures 0.8x0.6x0.6cm.cut surface grey brownc) received single node measures 1.2x1x0.8cmcut surface blue ink fatty infiltration.,section from breast parenchyma shows infiltrating neoplasm arranged in sheets nests and vague acini. the cells are round to oval vesicular nuclei prominent nucleoli. scant to moderate cytoplasm. adjacent stroma show fibrosis lymphoplasmacytic infiltrates noted.,a)right breast wide local excision:invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9(3+2+2).tumor measures 1.5 cm in greatest dimension.invasive component measures 1 cm.ductal carcinoma in situ component measures 0.5cm solid type.lymphovascular invasion not identified.perineural invasion not identified.deep margin is 2 cm away from the tumor.all resected margin free of tumor.b)hot node: one lymph node negative for malignancy (0 1).c) blue node+hot node: one lymph node negative for malignancy (0 1).pathological stage:pt1sn0
MR1902045,right breast lump carcinoma breast.,right breast lump biopsy.,received multiple grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section studied shows cores of breast parenchyma harboring infiltrative lesion arranged in sheets and nests. the cells are oval have pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. mitotic activity is discerned. stroma shows desmoplasia and lymphoplasmacytic infiltrate.,right breast lump biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1902061,right breast lump carcinoma breast.,biopsy from right breast lump.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion with cells arranged in sheets nests cords and trabecular. the cells have moderate cytoplasm pleomorphic hyperchromatic nuclei with prominent nucleoli in many. atypical mitosis are discerned (2 3 10hpf). surrounding stroma is desmoplastic with moderate lymphomononuclear infiltration.,right breast lump biopsy :invasive carcinoma nst grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1902125,left breast lump carcinoma breast.,left breast lump biopsy.,received five grey white linear cores measures 0.5 to 1.5cm.entire tissue processed.,sections studied shows cores of breast parenchyma harbors infiltrating lesion arranged in sheets and nests. the cells are oval have pleomorphic hyperchromatic nuclei and abundant eosinophilic cytoplasm. mitotic activity is discerned. stroma shows desmoplasia and mucin pools.,left breast biopsy :invasive carcinoma with mucinous features grade 2. modified bloom richardson score is 6(3+2+1).
MR1902164,case of left breast lump.,left breast biopsy.,received 4 grey white linear cores measures 1 2 cm. entire tissue processed.,section studied shows infiltrative lesion arranged in nests and sheets. the cells are oval have pleomorphic nuclei inconspicuous nucleoli and abundant eosinophilic cytoplasm. stroma shows desmoplasia and lymphoplasmacytic infiltrate. mitotic activity is discerned.,left breast biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1902183,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 1to1.5cm. entire tissue processed.,sections studied shows cores of breast parenchyma harbors infiltrative lesion arranged in diffuse sheets and nests. the cells are oval have pleomorphic hyperchromatic nuclei inconspicuous nucleoli and abundant eosinophilic cytoplasm. stroma shows desmoplasia and lymphoplasmacytic infiltrate.,right breast biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1902197,lump left breast,a) sentinel node biopsy.b) left breast conservative surgery.,a) received 2 lymph nodes largest measures 1x0.5x0.5cmcut surface dye stained2 lymph nodes measures 0.3x0.2x0.2cm.b)fresh tissue received : yeslaterality : left procedure : bcs specimen orientation : orientated specimen size :7x6x6 cm skin : presentskin abnormalities absent nipple : absent visible lesions : 01 grey white firm lesion lesion dimensions : 2.5x2.5x2cmdistance from margins:superior margin : 0.5cminferior margin :1cmmedial margin :0.9cmlateral margin :0.8cmdeep margin :0.5cm,sections from the lesion show invasive carcinoma composed of monomorphic cells in cords and indian file pattern. the cells show moderate cytoplasm round to oval hyperchromatic nuclei. many cells show plasmacytoid appearance. there are foci of inflammatory infiltrate.,a) sentinel node biopsy:section submitted for paraffin processing in one node show microscopic focus of metastatic deposit measures 0.2cm.(1 2).b) left breast conservative surgery:invasive carcinoma with lobular features tumor measures 2.5cm in greatest dimension.modified bloom richardson score is 3+2+1 6 9 grade 2.carcinoma in situ is not identified.lymphovascular invasion id not identified.perineural invasion is not identified.all resected margins including deep margin are free of tumor.pathological stage: pt2n1(sn)mi
MR1902203,left nipple discharge duct ectasia,left breast core biopsy,received cone excision specimen measuring 8x5x0.5cm on opening revealed a fibrotic lesion measuring 0.7x0.6x0.5cm.distance from margins:superior margin :2.2cminferior margin :3.1cmmedial margin :0.6cmlateral margin : 1cmdeep margin :1.2cm,section from the lesion shows few dilated ducts showing intraductal papillary lesion composed of both epithelial and myoepithelial cells with a fribrovascular core. the cells show crowded nuclei with minimal atypia. adjacent breast shows fibrocytic changes.all resected margins show normal ductal parenchyma and fibrofatty tissue.,left breast cone excision:intraductal papilloma.no evidence of in situ or invasive carcinoma in the material submitted.
MR1902219,right breast lesion carcinoma breast.,biopsy from right breast.,received multiple grey white linear cores measures 1.5 to 2cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion with cells arranged in nests cords and trabecular. the cells have scant cytoplasm and pleomorphic hyperchromatic nuclei. atypical mitoses are discerned (1 2 10hpf). surrounding stroma is desmoplastic. foci of ductal carcinoma in situ (solid cribriform type) of intermediate nuclear grade noted.,biopsy from right breast:invasive ductal carcinoma grade 2.modified bloom richardson score is (3+2+1) 6 9.foci of ductal carcinoma in situ (solid cribriform) noted.
MR1902224,right breast lump carcinoma breast.,biopsy from right breast.,received multiple grey white linear cores measures 0.2 to 1.5cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion composed of cells arranged in cords and trabeculae. the cells have highly pleomorphic nuclei with numerous mitoses (3 4 hpf). stroma is desmoplastic with moderate lymphomononuclear infiltrate.,biopsy from right breast:invasive carcinoma nst grade 3.modified bloom richardson score is (3+3+3) 9 9.
MR1902228,left breast lesion.,biopsy from left breast.,received five grey white linear cores measures 0.8 to 1.5 cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors. lesion arranged in tubules and nests. the cells are oval have pleomorphic nuclei inconspicuous nucleoli and moderate amount of of eosinophilic cytoplasm. mitotic activities is discerned. stroma shows desmoplasia.,left breast biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1902230,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections studied shows multiple linear cores harboring a neoplasm arranged as nests and sheets composed of cells with moderate granular to eosinophilic cytoplasm with hyperchromatic nucleus showing moderate pleomorphism .intervening stroma shows hyalinisation.,left breast lump :invasive ductal carcinoma grade 2. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1902231,left breast lump carcinoma breast.,biopsy from left breast.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring a lesion composed of cells arranged in sheets and nests. the cells have moderate amount of cytoplasm and pleomorphic round to oval nuclei. stroma is desmoplastic.,biopsy from left breast:invasive carcinoma nst grade 2.modified bloom richardson score is (3+2+1) 6 9.
MR1902251,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 0.8to 1.3cm. entire tissue processed.,sections studied shows linear cores of breast parenchyma harboring a lesion arranged in nests composed of cells with moderate clear to eosinophilic cytoplasm with moderate nuclear pleomorphism. mitotic figures noted.,biopsy from left breast lump. :invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1902274,right breast lump carcinoma breast.,biopsy from right breast lump.,received grey white linear cores fragment measures 0.8 to 1.5cm.,sections show linear core4s of fibrous tissue harboring an infiltrative lesion composed of cells arranged in sheets and nests. the cells have scant to moderate pale eosinophilic to clear cytoplasm pleomorphic hyperchromatic nuclei with some having large bizarre nuclei. atypical mitoses are discerned (1 2 hpf). surrounding stroma is desmoplastic.,biopsy from right breast lump:invasive carcinoma nst grade 3.modified bloom richardson score is 3+2+3 8 9.
MR1902277,case of right breast carcinoma with peritoneal lesion.,a)blue + hot node.b)non blue non not node.c)peritoneal mass excisiond)right mastectomye)revised base.,a)received 1 lymph node measures 1.7x1x0.9cm. entire tissue processed.b) received fibrofatty tissue measures 3x2x1cm2 lymph nodes isolated largest measures 0.9x0.8x0.6cm.c) received nodular mass measures 2.5x1.5x1.5cm.cut surface grey white lobulated.received in : formalinprocedure : mastectomy laterality : righttotal dimensions :medial to lateral :21cm superficial to deep :4.5cm superior to inferior:16cmskin ellipse :13x10cm nipple : normal scar surgical defect :not seentumor : singletumour size : 3x2.2x2cm location of tumor : lower outer quadrantmargin of tumor : infiltrative deep margin :0.3cmmuscle :3x1cmadjacent breast : fibrofatty axillary tail :absente) received fibrofatty tissue measures 2x1x0.8cm.,a) blue +hot node 1 node examined is free of tumor (0 1).b) non blue non hot node:2 nodes examined are free of tumor (0 2)c)section from the peritoneal mass show circumscribed spindle cell neoplasm with cells arranged in short fascicles . there are hypo and hypercellular areas. the cells show moderate cytoplasm elongated wavy nuclei with minimal pleomorphism.d)section from the mastectomy shows invasive neoplasm in tubules cords and aggregates of tumor cells with moderate pleomorphism in a desmoplastic stroma.e) revised base shows skeletal muscle that is free of tumor.,a)blue + hot node:1 node is free of tumor (0 1).b) non blue non not node:2 nodes are free of tumor (0 2).c)peritoneal mass excision:benign spindle cell neoplasm suggest ihc.d)right mastectomyhistological type: invasive ductal carcinoma.grade:2tumor measures 3 cm in maximum dimension.invasive component measures 2.5 cm.ductal carcinoma in situ measures 0.5cm.modified br score is 7 9tubule formation:2 nuclear pleomorphism: 2mitotic figures: 2ductal carcinoma in situ present comedo type lymphovascular invasion is not identified .perineural invasion is not identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.sentinel lymph nodes :3 lymph nodes no metastatic deposit of tumor. e) revised base :shows skeletal muscle is free of tumor.
MR1902290,left breast lump carcinoma breast.,biopsy from left breast lump.,received 6 grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section shows linear cores of fibrofatty tissue infiltrated by neoplasm cells arranged in sheets abortive tubules and clusters. the cells have round to oval hyperchromatic nuclei and moderate cytoplasm .surrounding stroma is desmoplastic.,biopsy from left breast lump.invasive carcinoma nst grade ii. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1902313,left breast lump carcinoma breast.,biopsy from left breast lump.,received four grey white linear cores measures 0.5 to 1.5 cm. entire tissue processed.,sections studied shows cores of breast parenchyma harbors infiltrative lesion arranged in nests and trabeculae. the cells are oval hyperchromatic pleomorphic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. mitotic activities in discerned. stroma shows desmoplasia.,left breast biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is (3+2+1) 6 9
MR1902334,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.5 to 0.8cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion with cells arranged in tubular pattern clusters and cords. the cells have moderate cytoplasm round to oval nuclei. atypical mitoses are occasional. surrounding stroma is desmoplastic.,biopsy from left breast lump:invasive ductal carcinoma grade 1.modified bloom richardson score is 2+2+1 5 9
MR1902335,right breast retroareolar lesion to r o carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in cords and nests. the cells are oval have pleomorphic hyperchromatic nuclei inconspicuous nucleoli and abundant eosinophilic cytoplasm. mitotic activities is discerned. stroma shows desmoplasia.,right breast biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is (3+2+1) 6 9
MR1902338,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.2 to 1.5cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion with cells arranged in sheets nests clusters cords and trabeculae. the cells have moderate pale eosinophilic to clear cytoplasm pleomorphic hyperchromatic nuclei with some having prominent nucleoli. atypical mitoses are discerned (1 2 hpf). surrounding stroma is desmoplastic.,biopsy from left breast lump:invasive carcinoma nst grade 3.modified bloom richardson score is 3+2+3 8 9.focus of comedo necrosis seen.
MR1902354,left breast lump carcinoma breast.,biopsy from left breast lump.,received 5 grey white linear cores measures 1.5x2cm entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in sheets and nests. the cells are oval have pleomorphic hyperchromatic nuclei moderate amount of eosinophilic cytoplasm. mitotic activity in discerned stroma shows desmoplasia and lymphoplasmacytic infiltrates.,biopsy from left breast lump.invasive ductal carcinoma grade 2.modified bloom richardson score is 6 (3+2+1).
MR1902372,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 1.5 to 2cm. entire tissue processed.,sections shows linear cores of fibrofatty tissue infiltrated by neoplastic cells arranged in clusters cords and nests. the cells have round nuclei inconspicuous nucleoli and moderate cytoplasm. surrounding stroma shows mucin lakes.,biopsy from left breast lump.invasive carcinoma with mucinous features grade ii.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1902378,left breast lump carcinoma breast.,left breast lump biopsy.,received 4 grey white linear cores measures 0.8 to 1.5cm. entire tissue processed.,sections show linear cores of breast parenchyma harboring an infiltrative lesion with cells arranged cribriform pattern cords and trabeculae. the cells have scant to moderate cytoplasm. round to oval nuclei. atypical mitoses are discerned (1 2 10hpf). surrounding stroma shows sclerosis and desmoplasia. also there are few foreign body giant cells. foci of ductal carcinoma in situ (cribriform solid type) of low grade seen.,left breast biopsy :invasive carcinoma nst grade 1modified bloom richardson score is 5 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9 .........
MR1902384,left breast lump carcinoma breast.,biopsy from left breast.,received multiple grey white linear cores measures 0.5 to 1cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion with cells arranged in sheets and nests. the cells have moderate cytoplasm and pleomorphic round to oval hyperchromatic nuclei. abundant extracellular mucin seen.,biopsy from left breast:invasive carcinoma with mucinous features grade 2.modified bloom richardson score is 3+2+1 6 9
MR1902385,case of left breast carcinoma post lumpectomy done outside.,left sentinel lymph nodes: a) hot node. b) blue + hot node. c) non blue non hot node.d) left breast left mastectomy.e) revised base.,a) received fibrofatty tissue measures 1.5 x 1 x 0.5 cm.one lymph node isolated measures 1.3 x 0.8 x 0.5 cm.b) received single node measures 0.8 x 0.5 x 0.4 cm. cut surface is grey brown.c) received fibrofatty tissue measures 0.6 x 0.4 x 0.3 cm.single tiny node measures 0.3 x 0.3 x 0.2 cm. entire tissue processed.d) received in : formalin.procedure : left mastectomy.laterality : left.total dimensions : medial to lateral 17 cm. superficial to deep 4 cm. superior to inferior 17 cm.skin ellipse : 14 x 9 cm.nipple : retracted and puckering seen.scar surgical defect : 2 cm corresponding to the underlying.tumor : single.location of tumor : retroareolar and central quadrant.tumor size : 3 x 2.5 x 2 cm. margins of tumor : illdefined.deep margin : 2cm.muscle : absentadjacent breast : fibrofatty tissue. axillary tail : nodistance from the margins:superior margin 4 cm.inferior margin 5 cm.medial margin 6 cm.lateral margin 4 cm.representative sections are submitted.e) received muscle measures 2 x 1.5 x 1 cm. entire tissue processed.,a) section studied shows one lymph node with preserved architecture. no tumor deposit is noted.b) section studied shows one lymph node with preserved architecture. no tumor deposit is noted.c) section studied shows one lymph node with preserved architecture. no neoplastic cells are noted.d) section from breast shows an invasive neoplasm arranged in tubules nests and cords. the cells have round hyperchromatic nuclei and moderate cytoplasm. extracellular mucin lakes are noted. surrounding stroma shows desmoplasia.e) section shows fibromuscular tissue with extensive cautery artifact. no viable tumor cells seen.,d) left breast left mastectomy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(2+2+2). tumor is located in the retroareolar area and the central quadrant. tumor measures 3 cm in greatest dimension. tumor is reaching upto the skin(dermis) of the nipple and areola with ulceration. ductal carcinoma in situ is not seen. lymphovascular invasion is not identified. perineural invasion is not identified. posterior resection margin is free of tumor.left sentinel lymph nodes:a) hot node:one lymph node identified negative for malignancy (0 1).b) blue + hot node:one lymph node identified negative for malignancy (0 1).c) non blue non hot node:one lymph node identified negative for malignancy (0 1).e) revised base:free of tumor.pathological stage : pt2n0
MR1902400,multiple lesion right breast.,biopsy from right breast lesion.,received four grey white linear cores measures 0.5x1cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in diffuse sheets and nests. the cells are oval have pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. mitotic activity is discerned. stroma shows desmoplasia and lymphoplasmacytic infiltrate.,biopsy from right breast lesion :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1902455,right breast lump carcinoma breast.,biopsy from right breast.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion with cells arranged in cords and trabeculae. the cells have scant cytoplasm and pleomorphic hyperchromatic nuclei. atypical mitoses discerned (5 6 10hpf). surrounding stroma is desmoplastic.,biopsy from right breast:invasive carcinoma nst grade 3.modified bloom richardson score is 3+3+2 8 9.
MR1902482,right breast lump carcinoma breast.,biopsy from right breast.,received multiple grey white linear cores measures 1.5 to 1.8cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion composed of cells arranged in cords and trabeculae. the cells have scant cytoplasm and hyperchromatic round to oval nuclei. atypical mitoses discerned (2 3 10hpf) surrounding stroma is desmoplastic.,biopsy from right breast:invasive carcinoma nst grade 2.modified bloom richardson score is 3+2+1 6 9
MR1902508,right axillary node.,biopsy from right axillary node.,received multiple grey white soft tissue bits measures 0.5 to 1.5cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion arranged in sheets and nests. the cells have scant to moderate cytoplasm pleomorphic hyperchromatic nuclei with some having prominent nucleoli. surrounding areas show fibrosis. no lymphoid elements seen.,biopsy from right axillary node:metastatic carcinoma in a known and treated case of carcinoma breast.please correlate clinically.
MR1902510,right breast lump carcinoma breast.,biopsy from right breast lump.,received three grey white linear cores measures 1 to 1.2 cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in sheets and nests and tubules. the cells are oval have pleomorphic hyperchromatic nuclei inconspicuous nucleoli and abundant eosinophilic cytoplasm mitotic activity is discerned. stroma shows desmoplasia.,right breast biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1902588,carcinoma right breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section studied shows linear cores of breast parenchyma with ducts having proliferation of monomorphic population of cells arranged in a solid and vague cribriform pattern. no evidence of invasive component is noted.,right breast lump biopsy :small focus of ductal carcinoma in situ. ( low to intermediate grade).
MR1902591,right breast lump carcinoma breast.,biopsy from right breast lump.,received 3 grey white linear cores measures 0.4 to 0.8cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in diffuse sheets and nests. the cells are oval have pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. mitotic activities is discerned. stroma shows lymphoplasmacytic infiltrates.,right breast biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MR1902602,right breast lump carcinoma breast.,biopsy from right breast lump.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in nests and cords. the cells are oval have pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. stroma shows desmoplasia. mitotic activities is discerned.,right breast breast :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1902603,right breast mass carcinoma breast.,biopsy from right breast mass.,received 3 grey white linear cores measures 0.8 to 1.5cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion with cells in cords and trabeculae. the cells have scant cytoplasm and pleomorphic hyperchromatic nuclei. atypical mitoses discerned. foci of ductal in situ (solid cribriform type) of intermediate nuclear grade seen.,right breast biopsy :invasive carcinoma nst grade 1modified bloom richardson score is (3+1+1) 5 9ductal carcinoma in situ (solid cribriform) intermediate nuclear grade.
MR1902626,right breast mass carcinoma breast.,right breast mass biopsy.,received 4 grey white linear cores measures 0.8 to 1.4cm. entire tissue processed.,section shows cores of breast parenchyma with a infiltrating lesion arranged as nests and cords. also seen are exclusive ductal carcinoma in situ with solid and cribriform pattern. the lesional cells have round to oval nuclei with moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. intervening stroma is desmoplastic.,right breast mass biopsy :invasive ductal carcinoma with extensive ductal carcinoma tin situ grade 1. modified bloom richardson score is 5 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9 .........
MR1902661,right breast mass carcinoma breast.,biopsy from right breast mass.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an invasive neoplasm arranged in cords. the lesional cells have moderate eosinophilic cytoplasm and pleomorphic hyperchromatic nucleus.surrounding stroma shows desmoplastic reaction.mitotic figures are discerned.,right breast mass :invasive carcinoma nst grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1902665,carcinoma left breast.,c) nipple sparing mastectomy specimen (left side)d) revised anterior marginb) tissue below nipple areola complex.a) left axillary sentinel lymphnodes e) axillary lymph node dissection,c) nipple sparing mastectomy specimen (left side)single fibrofatty tissue measures 21x15x4.5cm. cut surface shows irregular grey white measures 6.2x5x2cm. distance from margins :anterior margin : 0.1 cmposterior margin : 2.5 cmd) received fibrofatty tissue measures 1.5x1x0.3cm. entire tissue processedb) received single fibrofatty tissue measures 3.2x1.8x0.2cm. entire tissue processed. a) received fibrofatty tissue measures 2.5x2x1cm. isolated two lymphnodes.largest lymphnode measures 1.3x1x0.8cm. e) received fibrofatty tissue measures 8x6x3.5cm. largest lymphnode measures 2.5x1.5x0.5cm. cut section unremarkable,c) sections studied shows breast parenchyma with extensive areas of ductal carcinoma in situ in cribriform papillary solid and comedo pattern with high nuclear grade. the cells are round with moderate eosinophilic cytoplasm round hyperchromatic nucleus and prominent nucleoli. lymphomononuclear invasion is not identified.,c) nipple sparing mastectomy specimen (left side)extensive ductal carcinoma in situ(solid comedonecrosis pattern 1.5 cm) with multiple small foci of invasion largest focus measuring measuring 0.5cm(nuclear grade 2)anterior margin shows dcis posterior margin are free of tumour d) revised anterior margin. free of tumor b) tissue below nipple areolar complex. shows normal breast parenchyma.a) left axillary sentinel node biopsy : one of two lymphnodes isolated shows metastatic deposit of tumor (1 2). e) axillary lymph node dissection. isolated 12 lymph nodes all are free of tumor(0 12).
MR1902674,right breast lump.,biopsy from right breast lump.,received 3 grey white linear cores measures 0.3 to 0.8cm. entire tissue processed.,sections studied shows cores of breast paranchyma harbors lesion arranged in sheets and nests. the cells are oval have pleomorphic hyperchromatic nuclei inconspicuous cytoplasm. stroma shows desmoplasia and hemorrhage.,right breast biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1902676,right breast 9 0 clock lesion multicentric carcinoma breast metastases from rcc.,biopsy from right breast lesion.,received 4 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section studied cores of breast parenchyma harbors infiltrative lesion arranged in nests and sheets. the cells are oval have pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. stroma desmoplasia and lymphoplasmacytic infiltrate. mitotic activity is discerned.,right breast biopsy.invasive ductal carcinoma grade 2. modified bloom richardson scores 6(3+2+1).
MR1902688,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 0.6 to 0.8cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring an invasive neoplasm arranged in cords predominantly. the cells have round to angulated hyperchromatic nucleus and moderate cytoplasm. mitosis is discerned.,right breast lump :invasive carcinoma with lobular features grade ii. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1902702,case of left breast carcinoma.,a)left breast wide excision.b) sentinel hot node.b) sentinel blue +hot node.,a)fresh tissue received : yeslaterality : left specimen orientation : orientated specimen size : 4.8x4.6x3cm skin : present skin dimensions : 3x0.5cm skin abnormalities : absent nipple : absent lesion(s) : presentlesion dimensions : 1.7x1.4x1.2cmdistance of lesion from margins :superior margin :1.1cminferior margin :1.1cmmedial margin :1.4cmlateral margin :1.6cmdeep margin :0.3cm b) received 2 lymph nodes largest measures 0.5x0.5x0.5cm.other measures 0.4x0.3x0.2cm. c) received fibrofatty tissue measures 2x1.5x1cm.isolated 1 lymph node measures 0.8x0.6x0.5cm. cut surface grey brown.,section from the beast lesion show nests of tumor cells with moderate cytoplasm cribriform round nuclei with stapled chromatin. there are areas of low grade ductal carcinoma in situ solid type.,a)left breast wide excision:invasive ductal carcinoma nst.invasive component measures 4cmductal carcinoma in situ measures 0.8cmmodified bloom richardson score is 3+1+2 6 9ductal carcinoma in situ is solid type low grade.lymphovascular invasion is not identified.perineural invasion is not identified.b) sentinel hot node: 2 noes is free of tumor (0 2).b) sentinel blue +hot node: 1 node is free of tumor (0 1)
MR1902734,carcinoma left breast.,biopsy from left breast lump.,received 5 grey white linear cores measures 0.8 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in abortive tubules clusters and cords. the cells have round hyperchromatic nucleus and moderate cytoplasm. marked desmoplastic stroma is noted. mitotis is discerned.,left breast lump :invasive carcinoma nos grade iimodified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1902744,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma with an invasive neoplasm arranged in tubules cords and nests. the cells have round hyperchromatic nucleus and moderate eosinophilic cytoplasm. stroma is desmoplastic. mitoses is discerned.,right breast lump :invasive ductal carcinoma grade ii.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 .........
MR1902780,right breast lesion birads iv,biopsy from right breast biopsy.,received four grey white linear cores measures 0.5 to 0.8cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in sheets and nests. the cells are oval have markedly pleomorphic hyperchromatic nuclei inconspicuous nucleoli and abundant eosinophilic cytoplasm. mitotic activity is discerned. stroma shows lymphoplasmacytic infiltrate and desmoplasia.,right breast biopsy :invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+3+2).
MR1902789,carcinoma right breast.,right breast biopsy.,received 5 linear cores measures 0.6 to 0.1cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion with cells arranged in sheets and cords. the cells have moderate cytoplasm and pleomophic hyperchromatic nuclei. atypical mitoses discerned (1 2 10hpf). stroma is desmoplastic with moderate lymphomononuclear infiltrate.,right breast biopsy :invasive carcinoma nst grade 2.modified bloom richardson score is (3+2+1) 6 9
MR1902803,carcinoma right breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 0.5 to 1.5cm. entire tissue processed.,sections show linear cores of fibrofatty tissue harboring an infiltrative lesion with cells arranged in cords and trabeculae. the cells have scant cytoplasm and pleomorphic hyperchromatic nuclei. atypical mitosis are discerned (3 4 10hpf). stroma is desmoplastic with mild lymphomononuclear infiltrate.,right breast biopsy :invasive carcinoma nst.modified bloom richardson score is (3+2+1) 6 9
MR1902807,carcinoma right breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion with cells arranged in cords trabeculae and vague acinar pattern. the cells have scant cytoplasm and pleomorphic hyperchromatic nuclei. atypical mitosis are discerned (1 2 10hpf). stroma is desmoplastic.,right breast biopsy :invasive carcinoma nst grade 2.modified bloom richardson score is 7 9
MR1902814,carcinoma left breast.,biopsy from left breast lump.,received 5 grey white linear cores measures 0.8 to 1.2cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in nests trabeculae cords and sheets. the lesional cells are round to oval small having hyperchromatic nuclei and scant cytoplasm stroma shows desmoplasia.,left breast lump biopsy :invasive carcinoma nst grade 1.modified bloom richardson score is (3+1+1) 5 9
MR1902824,carcinoma left breast ct2n1m0,left modified radical mastectomy.,received in : formalinprocedure : modified radical mastectomy laterality : lefttotal dimensions :medial to lateral :23cm superficial to deep :7cm superior to inferior:20cmskin ellipse : 11x7cm nipple : normal scar surgical defect :absenttumor : singletumour size : 3.2x1.9x1.6cmlocation of tumor : upper outer quadrantmargin of tumor : infiltrativedeep margin :2cm from tumormuscle : 2x1x1cmadjacent breast : fibrofatty axillary tail :9x5x2cmsize of largest node :2.2x2x1cm cut surface grey white,tumor : shows invasive neoplasm composed of nests tubules and aggregates of tumor cells with moderate cytoplasm round nuclei with granular coarse chromatin.,left modified radical mastectomy:histological type: invasive carcinoma nstgrade:2tumor measures (maximum dimension) 3.2 cm.invasive component measures 3cm.ductal carcinoma in situ measures 0.2 cm.modified br score is 7 9tubule formation: 2nuclear pleomorphism: 3mitotic figures: 2ductal carcinoma in situ is occasionally present solid type intermediate grade. lymphovascular invasion is present.perineural invasion not identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: 13 lymph nodes metastasis: 1(1 13) measures 1.2cm with extranodal extension.pathological stage: pt2n1. summary:invasive ductal carcinoma nst left modified radical mastectomy.tumor grade:iilymphnode status:1 out of 13 nodes show tumor deposit measuring 1.2cm. extranodal extension present.
MR1902831,right breast lump carcinoma breast.,biopsy from right breast lump.,received 5 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in sheets and nests. the cells are oval have pleomorphic hyperchromatic nuclei prominent nucleoli and abundant eosinophilic cytoplasm. mitotic activity is discerned. stroma shows desmoplasia lymphoplasmacytic infiltrate and foci of necrosis.,right breast biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1902838,carcinoma right breast.,biopsy from right breast lump.,received 5 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion with cells in sheets and nests. the cells have scant cytoplasm highly pleomorphic hyperchromatic nuclei. atypical mitoses discerned (5 6 10hpf) stroma is desmoplastic with moderate lymphomononuclear infiltrate. few bizarre giant cells are seen. foci of ductal carcinoma in situ (solid cribriform type) of intermediate nuclear grade seen.,right breast biopsy :invasive carcinoma nst grade 3.modified bloom richardson score is (3+3+2) 8 9
MR1902850,right breast lump carcinoma breast.,biopsy right breast lump.,received 4 linear cores grey white to grey brown measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring an infiltrating lesion arranged in linear cords and sheets. the cells have round to oval hyperchromatic nuclei inconspicuous nucleoli and moderate eosinophilic cytoplasm.,right breast lump :invasive carcinoma nos grade ii.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1902887,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple 1 grey white to grey brown linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in nests sheets and tubules. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. mitosis 6 7 10hpf.,left breast lump biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is (2+2+2) 6 9
MR1902891,carcinoma right breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 0.5 to 1.5cm. entire tissue processed.,section show multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in cords tubules nests. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit marked nuclear pleomorphism. mitosis 3 4 10hpf. stroma shows desmoplasia.,right breast lump biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is (2+3+1) 6 9
MR1902906,right breast lump carcinoma breast.,right breast lump biopsy.,received multiple grey white linear core measures 0.8 to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma with foci of extracellular pools of mucin with nests of cells floating in it. the cells are round to oval having hyperchromatic nuclei and cytoplasm.,right breast lump biopsy :mucinous carcinoma nuclear grade ii.
MR1902920,carcinoma right breast.,biopsy from right breast lump.,received multiple grey white linear cores measures 0.5 to 1.5cm. entire tissue processed.,section show multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in nests and cords. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. stroma shows desmoplasia. mitosis 6 7 10hpf.,right breast lump biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is (3+2+2) 7 9
MR1902958,right breast lump.,right breast lump.,received specimen of breast lump measures 9x5.5x3cm.cut section shows circumscribed grey white areas measuring 1x0.8x0.5cm.adjacent parenchyma shows small cysts.overlying skin ellipse measures 4.5x1cm.distance of the lesion from the margins:superior margin 2cm.inferior margin 2.2cm.medial margin 4.5cm.lateral margin 3cm.deep margin 1cm.,section studied shows well circumscribed encapsulated lesion arranged in papillary pattern with fibrovascular core tubules and solid sheets. the cells are round to polygonal with moderate eosinophilic cytoplasm round nucleus with coarse chromatin prominent nucleoli moderate nuclear pleomorphism noted. periphery of the lesion shows preserved myoepithelial layer. adjacent breast shows ductal carcinoma in situ in papillary cribriform and solid pattern with bland nuclei. areas of calcification and hemorrhage seen. all the resected margins are free of tumor ( superior inferior medial lateral deep and skin).*immunohistochemistry:*calponin positive at periphery and around papillary fronds.*cytokeratin5 6 positive at periphery and around papillary fronds.*p63 positive at periphery and focally lost around few papillary fronds.*cytokeratin7 positive in epithelial cells.*er positive in ductal carcinoma in situ foci.,right breast lump:morphology in correlation with ihc favor intraductal papilloma with dcis( low grade ductal carcinoma in situ).lesion measures 1cm in its greatest dimensionall the resected margins are free of tumor ( superior inferior medial lateral deep).overlying skin is unremarkable .
MR1902984,carcinoma left breast lump.,biopsy from left breast lump.,received 3 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in nests cords and tubules. the cells are oval have pleomorphic hyperchromatic nuclei and abundant eosinophilic cytoplasm. mitotic activity is discerned. stroma shows desmoplasia and lymphoplasmacytic infiltrate.,left breast biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1902997,carcinoma right breast.,a) right sentinel lymph nodeb)right sentinel lymph nodec) right mastectomyd)right axillary dissection,a)received fibrofatty tissue measures 3.5x1.5x1cm. isolated 4 lymph nodes.largest measures 2x1.2x0.4cm cut surface fatty infiltration.b) received single lymph node measures 0.3x0.3x0.3cm. entire tissue processedc)received in : formalinprocedure : mastectomy laterality :righttotal dimensions :medial to lateral : 15cm superficial to deep :5cm superior to inferior:14cmskin ellipse : 12x6cm nipple : normal scar surgical defect : absenttumor : singletumour size : 1.6x1.5x1.2cm location of tumor : lower outer quadrantmargin of tumor : ill defined deep margin :1.5cmmuscle : absentadjacent breast : fibrofatty tissueaxillary tail :absentd)fibrofatty tissue measures 8x6x4cm.largest nodes measures 0.6x0.5x0.5cm.,c)section studied from breast parenchyma harbours extensive ductal carcinoma in situ of solid cribriform papillary and focal comedo pattern with foci showing invasive carcinoma arranged in predominantly sheets and tubules. the cells are large with increased ratio with scant cytoplasm and hyperchromatic irregular nuclei with prominent nucleoli. stroma shows extensive desmoplasia. foci showing atypical ductal hyperplasia is also seen.,(abcd)right mastectomy:histological type:invasive carcinoma nos with extensive ductal carcinoma in situ.grade:2tumor measures maximum dimension 1.6 cm.invasive component measures 0.5 cm.ductal carcinoma in situ measures 1.1 cm.modified br score is 7 9tubule formation: 3 nuclear pleomorphism:2 mitotic figures: 2ductal carcinoma in situ: solid cribriform. lymphovascular invasion is not identified.perineural invasion is not identified.posterior resection margin is free of tumor.nipple and areola is free of tumor.lymph nodes: 15 lymph nodes metastasis: 1(1 15) . pathological stage: pt1pn1 summary: invasive carcinoma nst right mastectomy.tumor grade:2.lymph node status: 1 15.
MR1903005,right breast lump carcinoma breast.,biopsy from right breast lump.,received four grey white linear cores measures 1 to 1.5 cm. entire tissue processed.,section studied shows linear cores of fibrofatty tissue infiltrated by neoplastic cells arranged in sheets and clusters focal necrosis is noted. the cells have round hyperchromatic with moderate cytoplasm. surrounding stroma shows scattered inflammatory cells.,right breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1903046,right breast lump neoplastic.,biopsy from right breast lump.,received 4 grey white linear cores measures 1 to 1.5 cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in tubules of sheets. the cells have round hyperchromatic nuclei and moderate cytoplasm. surrounding stroma is desmoplastic. mitotic is discerned.,biopsy from right breast lump. invasive ductal carcinoma grade 2. modified bloom richardson score is 6(2+2+2).
MR1903053,nodular lesion in the left breast carcinoma left breast.,biopsy from left breast lump.,received three grey white linear cores measures 1 to 1.5 cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue infiltrated by neoplasm cells arranged in abortive tubules and cords. the cells have round hyperchromatic nucleus dispersed chromatic and moderate cytoplasm. surrounding stroma shows areas of hyalinization.,biopsy from left breast lump :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(2+2+2).
MR1903056,left carcinoma breast.,biopsy from left breast lump.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors lesion arranged in nests cords and sheets. the cells are oval have moderately pleomorphic hyperchromatic nuclei inconspicuous nucleoli and abundant eosinophilic cytoplasm. stroma shows desmoplasia congested capillaries and lymphocytic infiltrate.,left breast biopsy :invasive ductal carcinoma grade iimodified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1903062,carcinoma right breast.,biopsy from right breast lump.,received 3 grey white linear cores measures 1to 1.5cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative arranged nests cords and sheets. the cells are oval have moderate pleomorphic hyperchromatic nuclei inconspicuous nucleoli and abundant eosinophilic cytoplasm. mitotic activity is discerned. stroma shows dismoplasia lymphovascular invasion is identified.,right breast biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1903099,right breast lump carcinoma breast.,biopsy from right breast lump.,received 3 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections studied from linear cores of lesional tissue composed of tumor cells arranged in tubules nests and acinar pattern. the cells are round to oval with scant cytoplasm and large hyperchromatic irregular nucleus with occasional atypical mitotic present. prominent eosinophilic nucleoli. stroma shows desmoplasia.,right breast lump :invasive carcinoma nst grade ii. modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 .........
MR1903111,left breast lump carcinoma breast.,left breast lump biopsy.,received grey white linear cores measures 1 to 1.5acm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in nests and cords. the cells are oval have moderately pleomorphic hyperchromatic nuclei conspicuous nucleoli and abundant eosinophilic cytoplasm. mitotic activity is discerned. stroma shows desmoplasia.,left breast lump biopsy. :suggestive of invasive carcinoma nos grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1903112,right breast lump carcinoma breast.,biopsy from breast lump.,received 2 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections studied from linear cores of lesional tissue composed of an invasive neoplasm arranged in tubules nests and scattered isolated tumor cells. the cells are round to oval with scant cytoplasm and irregular hyperchromatic nucleus atypical mitosis 1 2 hpf. stroma shows desmoplasia.,right breast biopsy :invasive carcinoma nst grade ii.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 .........
MR1903182,carcinoma right breast.,biopsy from right breast mass.,received multiple grey white soft tissue bits measures 0.5 to 0.1cm. entire tissue processed.,section studied shows linear cores of breast parenchyma with ducts and fibromyxoid stroma. ducts of varying sizes lined by epithelial and myoepithelial layer. epitheliosis cystic dilatation of ducts are noted.,biopsy from right breast mass:no evidence of malignancy in the material submitted. representative tissue.suggest repeat biopsy if clinically indicated.
MR1903187,carcinoma right breast.,biopsy from right breast.,received grey white linear cores measures 1cm. entire tissue processed.,section studied show linear cores of breast parenchyma infiltrated by neoplastic cells arranged in sheets abortive tubules and in cords. the cells have round hyperchromatic nuclei and moderate cytoplasm. the stroma shows desmoplastic changes. mitotic is discerned.,biopsy from right breast. invasive ductal carcinoma. grade 2. modified bloom richardson score is 7(3+2+2).
MR1903206,left breast lump carcinoma breast.,biopsy from left breast lump.,received 6 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of breast parenchyma with an infiltrating lesion arranged as sheets nests and cords against a desmoplastic stroma. the cells show moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. mitotic figures discerned.,biopsy from left breast lump.invasive carcinoma nos.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1903211,carcinoma left breast.,biopsy from left breast.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in nests cords. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. stroma shows desmoplasia and lymphocytic infiltrate. mitosis 6 7 10hpf.,left breast biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 .........
MR1903212,carcinoma left breast.,a) left breast wide excision.b)left axillary dissection.,a)received wide local excision specimen measures 8.5x6.5x4cmcut surface show grey white lesion measures 3x2.5x1.5cm.distance from margins :superior margin :1.2cminferior margin :0.6cmmedial margin :1cmlateral margin :2cmdeep margin :0.9cmb) received fibrofatty tissue measures 12xx8x4cm.largest lymph node measures 1.5x0.5x0.5cm.cut surface deposit.,section from the lesion show invasive neoplasm composed of sheets and aggregates of tumor cells in a desmoplastic stroma. adjacent solid and cribriform type ductal carcinoma in situ noted.,a) left breast wide excision:invasive ductal carcinoma nst.modified bloom richardson score is 3+2+2 7 9 grade2.tumor measures 3cm in greatest dimension.invasive component measures 2.5cm.ductal carcinoma in situ measures 0.5cm and is solid and cribriform type.lymphovascular invasion not identified.perineural invasion not identified.all resected margins including deep margin are free of tumor.b)left axillary dissection:extensive gross examination done only 4 nodes dissected which are free of tumor. 0 4
MR1903218,right breast mass.,biopsy from right breast mass.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied from linear cores of lesional tissue harbors invasive neoplasm arranged in sheets. the cells are large with increase n:c ratio having scant cytoplasm and large irregular hyperchromatic nucleus having prominent eosinophilic nucleoli. mitoses 6 7 10hpf. stroma shows desmoplasia.,biopsy from right breast mass:invasive carcinoma nst grade ii.modified bloom richardson score is (3+2+2) 7 9.
MR1903268,right breast mass carcinoma breast.,biopsy from right breast mass.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections studied from linear cores of breast parenchyma harbors invasive neoplasm arranged predominantly in sheets and trabecular pattern . the cells are large scant cytoplasm and large hyperchromatic nucleus mitosis 1 2 hpf. stroma shows desmoplasia.,right breast lump biopsy :invasive carcinoma nstmodified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1903287,carcinoma left breast.,biopsy from left breast lump.,received six grey white linear cores measures 0.3 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in tubules and cords. the cells have round hyperchromatic nuclei and moderate eosinophilic cytoplasm. mitotic is discerned.,biopsy from left breast lump :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(2+2+2).
MR1903296,case of right breast lump.,a)right breast wide excision.b) revised base.,a)fresh tissue received : yes : laterality : right specimen orientation :orientated specimen size :5.5x4.5x2.5cm skin : presentskin dimensions : 3.0x1cmnipple : absent lesion(s) : presentnumber of macroscopically visible lesions : 01 circumscribed grey white fibrotic lesion with slit like spaceslesion dimensions :2x1.8x1.5cdistance of lesion from margins :superior margin : 1.5cminferior margin :1.8cmmedial margin :2cmlateral margin :2.5cmdeep margin :0.2cmb) received fibrofatty tissue measures 2x1.5x1cmone surface is striched.,section show circumscribed neoplasm composed of compressed ducts with preserved epithelial and myoepithelial layers in a sclerotic stroma. the cells show clear to eosinophilic cytoplasm with no atypia. few ducts show intra luminal sections. there are scattered lymphocytic aggregates. no evidence of in situ or invasive carcinoma seen.,a)right breast wide excision:fibroadenomaall resected margins are free of tumor.b) revised base: is free of tumor.
MR1903300,carcinoma right breast,biopsy from right breast lump.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections studied shows cores of breast parenchyma harbors infiltrative lesion arranged in nests cords and sheets. the cells are oval have moderate pleomorphic hyperchromatic nuclei inconspicuous nucleoli and abundant eosinophilic cytoplasm. mitotic activity is discerned. stroma shows desmoplasia and lymphocytic infiltrate.,right breast biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1903307,carcinoma right breast.,biopsy from right breast.,received 3 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in nests and islands. the lesional cells are round to oval having hyperchromatic nuclei and scant cytoplasm. cells exhibit marked nuclear pleomorphism. mitosis 6 7 10hpf. stroma shows desmoplasia mixed inflammation necrosis.,right breast biopsy :invasive ductal carcinoma grade 3.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9 .........ductal carcinoma in situ comedo type and cribriform type seen.
MR1903327,right breast lump carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections studied from linear cores with of breast parenchyma harboring invasive neoplasm arranged in sheets and trabecular pattern. the cells are large with scant cytoplasm and large hyperchromatic irregular nucleus atypical mitosis 10 10hpf seen. stroma shows desmoplasia.,right breast lump biopsy :invasive carcinoma nst grade iii. modified bloom richardson score is 9 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 3 9 9 .........
MR1903347,right breast lump carcinoma breast.,right breast lump.,receive 4 grey white linear cores measures 1 1.5cm. entire tissue processed.,section studied shows cores of fibrous tissue harboring an infiltrative lesion arranged in sheets nests and cords . the cells are oval have moderately pleomorphic hyperchromatic nuclei prominent nucleoli and abundant eosinophilic cytoplasm. mitotic figures are discerned. stroma shows lymphocytic infiltrate and foci of necrosis.,right breast lump:invasive ductal carcinoma grade 2.modified bloom richardson score 7 9.tubule formation :3nuclear pleomorphism: 2mitosis : 2 7 9
MR1903357,right breast lump carcinoma breast.,biopsy from right breast lump.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in tubules acini and cribriform pattern. the cells have round hyperchromatic nuclei with moderate eosinophilic cytoplasm. mitosis is discerned.,biopsy from right breast lump:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(2+2+2).
MR1903372,left breast lump.,left breast lump biopsy.,received 4 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section show multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in nests and sheets. the cells are round to oval having markedly pleomorphic hyperchromatic nuclei and scant cytoplasm. stroma shows desmoplasia lymphoplasmacytic infiltrate histiocytes mitosis 8 10 hpf. areas of necrosis seen.,left breast lump biopsy :invasive carcinoma nst grade 3.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 3mitotic figures : 2 8 9 .........areas of necrosis seen.
MR1903388,right breast mass. carcinoma breast.,biopsy from right breast mass.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied from linear cores of breast parenchymal harboring invasive neoplasm arranged in sheets and trabecular pattern. the cells are large having increase n:c ratio with scant cytoplasm and hyperchromatic irregular nuclei. stroma shows desmoplasia with lymphoplasmacytic infiltrate.,biopsy from right breast mass:invasive carcinoma nst grade ii.modified bloom richardson score is (3+2+2)7 9
MR1903391,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma showing ducts. periductal stroma shows lymphoplasmacytic infiltrate. focal necrosis seen.,left breast lump biopsy :chronic mastitis with suppuration. no evidence of malignancy in the smears studied.
MR1903437,right breast lump carcinoma breast.,right breast lump biopsy.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows cores of fibrous tissue harbors infiltrative lesion arranged in diffuse sheets. the cells are oval have moderate pleomorphic dark nuclei prominent nucleoli and abundant eosinophilic to clear cytoplasm. mitotic figures are discerned. stroma shows areas of necrosis.,right breast lump biopsy :invasive carcinoma grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1903439,right breast lump carcinoma breast.,biopsy from right breast lump.,received 3 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in acini fused papillae cords. the cells are round to oval having hyperchromatic nuclei moderate cytoplasm. few plasmacytoid cells seen. cells exhibit mild nuclear pleomorphism. mitosis 5 6 10hpf.,right breast lump biopsy :invasive carcinoma grade 1.modified bloom richardson score is 5 9tubule formation : 2nuclear pleomorphism : 1mitotic figures : 2 5 9 .........
MR1903458,carcinoma right breast.,a) right sentinel hot node.b)right sentinel blue +hot node .c) right sentinel non blue non hot node.d) right mastectomy.,a) received fibrofatty tissue measures 0.8x0.5x0.5cmisolated 1 lymph node.b) received fibrofatty tissue measures 4x3x2cmisolated 4 lymph nodeslargest measures 2.2x1.7x0.6cmcut surface fatty infiltration.c) received 5 lymph nodes measures 0.6x0.5x0.5cmcut surface fatty infiltration.d)received in : formalinprocedure : mastectomy laterality : righttotal dimensions :medial to lateral :25cm superficial to deep :7.5cm superior to inferior:15cmskin ellipse : 15x9cm ulcer measures 1.4x0.8cmnipple : unremarkablescar surgical defect : absenttumor : singletumour size : 10.4x9.5x6.4cmlocation of tumor : upper inner quadrantmargin of tumor :circumscribed solid grey white fleshy with areas of hemorrhage and slite like spacesdeep margin :0.1cmmuscle : absentadjacent breast : fibrofatty tissueaxillary tail :absent,section from the lesion show partially circumscribed neoplasm composed of sheets and short fascicles of spindle to pleomorphic cells with marked atypia in a hyalinised stroma. there is diffuse infiltration of numerous osteoclast like giant cells within the tumor . focal osteoid like areas seen. extensive necrosis present. mitosis is brisk.,a) right sentinel hot node:1 lymph node is free of tumor (0 1)b)right sentinel blue +hot node :4 lymph nodes are free of tumor free of tumor (0 4)c) right sentinel non blue non hot node:5 nodes are free of tumor (0 5).d) right mastectomy:poorly differentiated malignancy. possibilities are1. high grade sarcoma2. metaplastic carcinoma with osteoclast giant cells.suggest ihctumor measures maximum dimension 10.4cmductal carcinoma in situ is not identified. lymphovascular invasion not identified.perineural invasion not identified. posterior resection margin is free of tumor nipple and areola is unremarkable.summary:poorly differentiated malignancy possibilities are1. high grade sarcoma2. metastatic carcinoma with osteoclast giant cellslymph node status : 10 sentinel nodes isolated are free of tumor (0 10).suggest ihc.
MR1903466,left breast lump carcinoma breast.,left breast biopsy.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows cores of fibrous tissue shows dilated ducts showing proliferative of epithelium inconspicuous nucleoli. ducts are lined by myoepithelium layer.,left breast biopsy :ductal carcinoma in situ low to intermediate nuclear grade. note:case discussed with dr.senthil
MR1903492,carcinoma left breast.,biopsy from left breast.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in cords nests and tubules. the cells have round hyperchromatic nuclei and moderate cytoplasm. mitosis is discerned.,biopsy from left breast:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1903502,left breast lump carcinoma breast.,biopsy from left breast lump.,received 3 grey white linear cores measures 1.5cm. entire tissue processed.,section shows linear ares of breast parenchyma harboring an infiltrating lesion arranged in tubules cords and nests. the cells have round hyperchromatic nuclei and moderate eosinophilic cytoplasm. surrounding stroma shows hyalinization.,left breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(2+2+2+).
MR1903542,carcinoma left breast.,a) left breast wide excision.b) sentinel blue+hot node.c) sentinel hot node.,a)fresh tissue received : yeslaterality : left specimen orientation : orientated specimen size : 8.5x7x5cm skin : presentskin dimension : 5.5x2cmlesion(s) : presentlesion dimensions : 2.5x2.0x2.0cmdistance from margin:superior margin :2.5cminferior margin :1cmmedial margin :2cmlateral margin :1.5cmdeep margin : 4cmb) received fibrofatty tissue measures 2x1x0.6cm.no lymph nodes found.c)received fibrofatty tissue measures 4x2.5x1.5cm.largest node measures 3.5x2x1.4cm.cut surface fatty infiltrative isolated 3 nodes.,section from the lesion shows an invasive neoplasm in sheets and nests. the tumor cells show moderate pleomorphism hyperchromatic nuclei and brisk mitosis. extensive geographic necrosis seen. adjacent breast show usual ductal hyperplasia with columnar cell and apocrine changes.,a) left breast wide excision:invasive ductal carcinoma nst.modified bloom richardson score is 3+2+3 8 9 grade 3.tumor measures 2.5cm in greatest dimension.ductal carcinoma in situ not identified.lymphovascular invasion not identified.perineural invasion is not identified.all resected margins are free of tumor.b) sentinel blue+hot node:no nodes isolated only adipose tissue seen.c) sentinel hot node:2 nodes examined are free of tumor (0 2).pathological stage : pt2n0(sn).
MR1903573,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrofatty tissue infiltrated by tumor cells arranged in sheets and singly scattered with large areas of necrosis. the cells have round hyperchromatic nuclei inconspicuous nucleoli and moderate cytoplasm.,biopsy from left breast lump:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2)
MR1903583,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 linear cores measures 1 to 1.5cm. entire tissue processed.,sections show linear cores of tumor composed of round to oval cells arranged as nests. these cells show moderate pleomorphism enlarged hyperchromatic nucleus and moderate cytoplasm mitosis are discerned. necrosis is seen. stroma shows desmoplasia.,left breast lump biopsy :invasive carcinoma nst grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1903590,right breast lump.,biopsy from right breast lump.,received multiple grey white linear cores measures 1 to 1.5 cm. entire tissue processed.,section shows linear cores of fibrofatty tissue infiltrated by neoplastic cells arranged in cords tubules. also seen are ducts lined by monotonous population of cells forming cribriform and comedo pattern. mitosis is discerned.,biopsy from right breast lump:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(2+2+2). ductal carcinoma in situ present of cribriform comedo pattern with intermediate nuclear grade.
MR1903609,left breast mass carcinoma breast.,biopsy from left breast.,received grey white multiple linear cores measures 1 to 2cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring neoplastic cells arranged in tubules nests. the cells are pleomorphic having scant to clear cytoplasm and pleomorphic hyperchromatic nucleus. occasional atypical mitosis seen. stroma shows desmoplasia with mucinous change and scattered lymphoplasmacytic infiltrates.,biopsy from left breast:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1903612,right breast lump carcinoma breast.,right breast lump biopsy.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in cords and nests. the lesional cells are round to oval having hyperchromatic nuclei scant cytoplasm. stroma shows desmoplasia mitosis 5 6 10hpf.,right breast lump biopsy :invasive carcinoma with lobular features grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1903627,carcinoma right breast lump.,left breast lump biopsy.,received 4 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section studied shows cores of fibrous tissue harbours infiltrative lesion arranged in sheets nests and cords. the cells are oval have moderately pleomorphic hyperchromatic nucleoli inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. mitotic figures are discerned. stroma shows desmoplasia and areas of necrosis.,left breast lump biopsy :invasive ductal carcinoma grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1903628,left breast lump.,biopsy from left breast lump.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in nests and islands. the lesional cells are round to oval having moderately pleomorphic hyperchromatic nuclei and moderate cytoplasm. mitosis 5 6 10hpf. stroma shows desmoplasia lymphoplasmacytic infiltrate and histiocytes.,left breast lump biopsy :invasive carcinoma nst grade 2modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 8 9 .........
MR1903630,left breast lump.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section shows fragmented linear cores of fibrofatty tissue infiltrated by neoplastic cells arranged in nests and sheets with large areas of necrosis. the lesional cells have round hyperchromatic nuclei and moderate cytoplasm. few cells with bizarre nuclei are also seen.,biopsy from left breast lump:invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+3+2).
MR1903636,left breast lump carcinoma breast.,biopsy from left breast lump.,received 5 linear cores measures 0.5 to 0.8cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring invasive neoplasm arranged in sheets nests and glandular pattern. the cells are polygonal with abundant eosinophilic cytoplasm round moderately pleomorphic hyperchromatic nucleus prominent nucleoli. mitotic figures are 8 10 10hpf with atypical forms. stroma shows dense lymphomononuclear infiltrates.,left breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1903641,case of left breast carcinoma.,a) left breast wide excision.b) hot node.c) blue +hot node.d) revised medial margin.e) re revised medial margin.,a) received skin covered globular mass measures 7.5x7x5cm. skin ellipse measures 5.5x5cmgrey white firm to hard mas measures 5x4x3cmdistance from margins:superior margin :1.7cminferior margins :2cmmedial margin :5cmlateral margin :2cmdeep margin :1.5cmb) received two fibrofatty tissue largest measures 2x1x1cm.isolated 2 lymph nodes.largest measures 1x1x0.5cm.c) received single fibrofatty tissue measures 1x1x1cm.isolated 1 lymph node measures 1x1x0.5cm.d) received single fibrofatty tissue measures 3.8x3x1cm.e)received fibrofatty tissue measures 1.8x1x1cm.,section studied from breast parenchyma harbours invasive neoplasm arranged in cords nests and sheets. the cells are mildly pleomorphic with scant cytoplasm and hyperchromatic irregular nuclei cribriform and solid ductal carcinoma in situ present. stroma shows sclerosis with mucinous change. few benign ducts in between show fibrocystic change.,left breast wide excision:invasive ductal carcinoma nos.maximum size of tumor 5cm .invasive tumor measures 4cm in greatest dimension.modified bloom richardson score is 3+2+2 7 9.ductal carcinoma in situ solid and cribriform measures 1cm.lateral and superior inferior margins are free of tumor.medial and revised medial margin are involved by tumour. re revised medial margin is free of tumor.lymphovascular invasion is not identified.perineural invasion is not identified.sentinel lymph nodes isolated 3 nodes all are free of tumor.stage : pt2pn0
MR1903675,left breast mass carcinoma breast.,biopsy from left breast mass.,received 4 linear cores measures 2 cm. each entire tissue processed.,section studied shows linear cores of breast parenchyma harboring invasive neoplasm arranged in nests sheets trabeculae. the cells are round to polygonal with moderate eosinophilic cytoplasm round hyperchromatic nucleus prominent nucleoli some showing intranuclear inclusions stroma shows desmoplasia.,left breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(2+2+2).
MR1903699,right breast lesion carcinoma breast.,right breast lump.,received 4 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in tubules cords and cribriform pattern. the lesional cells are round to oval having hyperchromatic nuclei and scant cytoplasm. stroma shows hyalinisation. occasional mitosis seen.,right breast lesion biopsy :invasive ductal carcinoma grade imodified bloom richardson score is 5 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9 .........
MR1903713,right breast malignancy.,right breast biopsy.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in sheets cords and nests. the cells are oval have moderately pleomorphic hyperchromatic nuclei few shows conspicuous nucleoli and moderate amount of eosinophilic cytoplasm. mitotic figures are discerned. stroma shows desmoplasia. foci of necrosis and lymphocytic infiltrate seen.,right breast biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1903725,carcinoma left breast,a)left breast best conservative surgery.b)blue +hot nodes.c) hot nodesd)revised lateral margine) revised inferior marginf) left axillary dissection.g) left level iii nodes.,a)fresh tissue received : yes laterality : left specimen orientation : orientated specimen size : 6.5x5x4.5cm skin : present skin dimensions : 3x1.5cm skin abnormalities : absent number of macroscopically visible lesions : 22nd lesion is lateral and superior to 1st lesion the distance between 2 lesions is 0.6cm1st lesion measures 2.3x1.5x1.5cm.2nd lesion measures 0.7x0.5x0.5cm.distance from margins:1st lesion :superior margin :2cminferior margin :0.4cmmedial margin :1cmlateral margin :1cmdeep margin :0.6cm2nd lesion:superior margin :1cminferior margin :1cmmedial margin :3.5cmlateral margin :0.1cmdeep margin :1.5cmb)received fibrofatty tissue measures 1x1x0.6cm isolated 1 lymph node measures 0.9x0.6x0.5cm.cut surface grey white.c)received fibrofatty tissue measures 1.5x1x1cm 3 lymph nodes isolated largest lymph node measures 0.5x0.5x0.5cm.d)received fibrofatty tissue measures 5x2.5x0.5cmsuture side identified.e) received fibrofatty tissue measures 5x3.5x0.5cmsuture side identified.f) received fibrofatty tissue measures 11x7x6cmlargest lymph node measures 2.3x1x1cmcut surface fatty infiltration.g) received fibrofatty tissue measures 2x1x0.5.,section show breast parenchyma harboring an invasive neoplasm in nests and sheet like pattern. the cells show moderate cytoplasm round nuclei hyperchromatic with coarse chromatin.,a)left breast best conservative surgery:invasive ductal carcinoma nst.unifocal tumor (microscopic).(see comment)modified bloom richardson score is 7 9 3+2+2 grade 2.tumor measures 3cm invasive component measures 2cm.ductal carcinoma in situ measures 1cm and is solid and cribriform type.lymphovascular invasion is present.perineural invasion not identified. inferior and lateral margin are involved by tumor.all other margins are free of tumor.b)blue +hot nodes:1 out of 2 nodes show tumor deposit measures 0.3cm.(1 2).extranodal extension not identified.c) hot nodes: 1 out of 3 nodes show tumor deposit show tumor deposit measures 0.2cm (1 3).extranodal extension not identified.d)revised lateral margin: is free of tumor.e)revised inferior margin : is free of tumor.f) left axillary dissection: 18 nodes are free of tumor (0 18)g) left iii nodes 3 nodes examined are free of tumor(0 3)total 26 nodes 2 show metastatic deposits (2 26).pathological staging: pt2n1.comment : grossly tumor appears as 2 lesions. however tumor is unifocal on microscopy
MR1903754,left breast lump neoplastic.,biopsy from left breast lump.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in sheets and nests. the lesional cells are round to oval having hyperchromatic nuclei scant cytoplasm. cells exhibit moderate nuclear pleomorphism. stroma shows desmoplasia. brisk mitotic activity noted.,biopsy from left breast lump :invasive ductal carcinoma grade 3modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 .........
MR1903757,left breast lump carcinoma breast.,biopsy from left breast lump carcinoma breast.,received 4 grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section studied shows linear cores of breast parenchyma harboring invasive neoplasm arranged in glandular nests. the cells are polygonal with abundant eosinophilic to clear cytoplasm round hyperchromatic nucleus. some showing intranuclear inclusions. mitotic figures are 10 12 10hpf. stroma shows desmoplasia.,left breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1903764,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 linear cores measures 1.5 to 2cm. entire tissue processed.,section show cores of breast parenchyma with an infiltrating lesion arranged as sheets and cords. the lesional cells have round to oval hyperchromatic nuclei and moderate cytoplasm. crush artifacts noted. intervening stroma shows desmoplasia.,invasive carcinoma with lobular features. grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1903805,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in nests sheets and tubules. the lesional cells are round to oval having hyperchromatic nuclei scant cytoplasm. cells exhibit moderate nuclear pleomorphism. mitosis 2 3 10hpf.,left breast lump biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1903808,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section studied shows cores of breast parenchyma shows multiple dilated ducts shows luminal epithelial proliferation. the cells are oval have moderately pleomorphic hyperchromatic nuclei prominent nucleoli and moderate amount of eosinophilic cytoplasm. foci of necrosis is seen. myoepithelium is intact. stroma shows fibrosis and lymphocytic infiltration.,left breast biopsy :ductal carcinoma in situ (high grade)solid and comedo pattern.
MR1903812,carcinoma breast.,biopsy from right breast.,received 4 linear cores measures 0.5 to 1cm. entire tissue processed.,section shows cores of breast parenchyma with an infiltrating lesion arranged as sheets and nests. the lesional cells show moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. areas of necrosis noted. stroma shows desmoplasia and lymphocytic infiltrate.,biopsy from right breast. invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1903817,carcinoma right breast post mastectomy.,a) right completion mastectomy.b) right level ii lymph nodes.,a) received in : formalinprocedure : completion mastectomy with right axillary dissection.laterality : righttotal dimensions : medial to lateral 14cm. superficial to deep 2cm. superior to inferior 6cm.skin ellipse : 14x5cm.nipple : absent.scar surgical defect : present measures 13cm grey white area noted beneath the scar measures 0.4x0.2x0.1cm. deep margin : 1cm.muscle : 3cm.adjacent breast : fibrofatty tissue. axillary tail : 7x5x0.8cm.b) received fibrofatty tissue measures 1.5x1x0.3cm. entire tissue processed.,section from breast parenchyma shows areas of fibrosis necrosis and foreign body granulomas. no residual viable tumor is seen.,a) right completion mastectomy:no residual tumor seen.areas of fibrosis necrosis foreign body granulomas present.post lumpectomy changes.posterior resection margin is free of tumor.lymph nodes: 13 lymph nodes negative for malignancy (0 13).b) right level ii lymph nodes:three lymph nodes identified negative for malignancy (0 3).pathological stage: ypt0 ypn0summary:no residual viable tumor.lymphnode status: 0 16 (axillary lymphnodes: 0 13 level ii lymphnodes: 0 3)
MR1903839,left breast lump carcinoma breast.,biopsy from left breast.,received 3 linear cores measures 1.5 to 2cm. entire tissue processed.,section show cores of breast parenchyma with an infiltrating lesion arranged as sheets nests and cords the lesional cells have moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. stroma shows desmoplasia and lymphocytic infiltrate.,invasive ductal carcinoma.grade 2.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 .........
MR1903871,left breast lump carcinoma breast.,left breast lump.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of breast parenchyma with an infiltrating lesion cords islands and vague tubules. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma is desmoplastic with mild lymphomononuclear infiltrate.,left breast biopsy :invasive carcinoma nst grade 2. modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1903874,carcinoma breast.,biopsy from right breast.,received grey white linear cores measures 1 to 1.3cm. entire tissue processed.,section studied shows linear cores of breast parenchyma with an infiltrating lesion arranged in islands and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma is desmoplastic with areas of hemorrhage and mild lymphomononuclear infiltrate.,right breast biopsy :invasive carcinoma nst grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1903907,left breast lesion.,left breast lesion biopsy.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of breast parenchyma with an infiltrating lesion arranged as sheets nests and cords. the lesional cells show moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. stroma shows inflammatory infiltrate and areas of necrosis.,left breast lesion biopsy :invasive carcinoma nst grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1903926,carcinoma breast.,biopsy from left breast mass.,received 5 linear cores soft tissue bits measures 0.5 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by tumor cells arranged in cords and abortive tubules. the cells have round hyperchromatic nuclei and moderate cytoplasm. ductal carcinoma in situ component is also note of solid pattern.,biopsy from left breast mass :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1903947,right breast lump carcinoma breast.,biopsy from right breast lump.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in linear cords nests and abortive tubules. the cells have round hyperchromatic nuclei and moderate cytoplasm.,biopsy from right breast lump. invasive ductal carcinoma grade 2modified bloom richardson score is (3+2+1) 6 9
MR1903970,left breast lump.,left breast lump.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections shows linear cores of breast parenchyma with extensive areas of ductal carcinoma in situ solid type of intermediate nuclear grade. focus of invasive carcinoma infiltrating tumor cells in the sections studied.,left breast biopsy :small focus of invasive carcinoma with extensive ductal carcinoma in situ (solid type) intermediate grade
MR1903972,carcinoma right breast.,a) right sentinel lymph nodes.b) right breast lump wide local excision.c) revised superior margin.d) revised medial margin.,a)received fibrofatty tissue measures 1.5 x 1 x 1 cm.isolated 1 lymph nodes. entire tissue is submitted.b) received single globular mass measures 6.5 x 7 x 3.5 cm.tumor measures 4 x 3 x 2 cm.cut surface shows grey white irregular firm mass.distance from margins:superior margin :1.2 cminferior margin :1.2 cmmedial margin :0.3 cmlateral margin :2.5 cmdeep margin :1 cmrepresentative sections are submitted.c) received fibrofatty tissue measures 4 x 3 x 2 cm. representative sections are submitted.d) received fibrofatty tissue measures 5 x 4 x 2 cm. representative sections are submitted.,section from breast shows an invasive neoplasm arranged in cords clusters and tubules. the lesional cells have round nuclei coarse chromatin inconspicuous nucleoli and moderate cytoplasm. surrounding stroma shows desmoplasia.,a) right sentinel lymph nodes:one lymph node identified negative for malignancy.b) right breast lump wide local excision:invasive ductal carcinoma grade 2 modified bloom richardson score 7(3+2+2). tumor measures 4 cm in greatest dimension. lymphovascular invasion is not identified. perineural invasion is not identified. all margins of resection are free of tumor.c) revised superior margin: free of tumor.d) revised medial margin: free of tumor.
MR1904013,case of carcinoma right breast.,a) right breast wide excision of lumpectomy.b) blue node.c) blue + hot node.,a) received skin covered globular mass measuring 4x2.3x2.2cm. skin ellipse measures 3.3x0.7cm. cut surface show ill defined firm mass measuring 0.5cm.distance from the margins:superior margin 1.7cm.inferior margin 1cm.medial margin 1.5cm.lateral margin 1cm.deep margin 0.5cm.b) received single fibrofatty tissue measures 3x2x1cm.isolated 2 lymph nodes largest measures 1x1x0.5cm.c) received single fibrofatty tissue measures 2x1.5x1cm.isolated 1 lymph nodes largest measures 1x1x0.5cm.,section from breast parenchyma shows suture material surrounded foreign body giant cell reaction.,a) right breast wide excision of lumpectomy cavity:no residual viable tumor seen. foreign body giant cell reaction. all resected margins including deep are free of tumor.b) blue node:two lymph nodes identified negative for malignancy (0 2).c) blue + hot node:one lymph node identified negative for malignancy (0 1).
MR1904016,known case of right breast.,biopsy from right breast.,received 6 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,the section shows tumor cores of breast parenchyma showing expanded ducts. the ducts show round to ovoid luminal cells and enlarged round to ovoid nuclei and moderate cytoplasm. luminal cells show cribriform and papillary pattern. intervening sclerosis is noted.,right breast biopsy :shows features of ductal carcinoma in situ solid cribriform and papillary pattern with intermediate nuclear grade. no definite evidence of invasive malignancy is seen.suggest excision of the lump for further confirmation of the invasive component.
MR1904032,carcinoma left breast post lumpectomy.,sentinel nodes:a) hot node.b) blue + hot node.c) non blue non hot node.d) left breast wide excision of post lumpectomy cavity.e) revised deep margin.f) left completion axillary dissection.,a) received single fibrofatty tissue measures 1.5x1x1cm. isolated 1 node measures 1.5x1x1cm.b) received single fibrofatty tissue measures 1x1x1cm. isolated 1 node 1x0.5x0.5cm.c) received single fibrofatty tissue measures 1.5x1x1cm. isolated 1 node measures 1x0.5x0.5cm.d) received single fibrofatty tissue measures 4x3x2cms. cut surface shows gross no lesion identified. only form fibrous tissue present.e) received single fibrofatty tissue measures 2x1x1cm. entire tissue processed.f) received fibrofatty tissue measures 7x5x1cm.,section from lesional areas show areas of fibrosis and sclerosis with entrapped benign ductules. no evidence of invasive carcinoma in sections studied.,sentinel nodes:a) hot node:one lymph node isolated free of tumor (0 1).b) blue + hot node:one lymph node isolated shows metastatic deposit measures 0.3 cm with extranodal extension(1 1).c) non blue non hot node:one lymph nodes isolated free of tumor (0 1).d) left breast wide excision of post lumpectomy cavity:no residual tumor is seen. superior medial inferior lateral and deep margins of resection are free of tumor.e) revised deep margin:free of tumor.f) left completion axillary dissection:four lymph node isolated free of tumor (0 4).
MR1904037,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in cords nests. the cells have round hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm. also seen are extracellular mucin pools.,right breast lump core biopsyinvasive carcinoma with mucinous features grade 2. modified bloom richardson score is 6(3+2+1).
MR1904040,left breast lump carcinoma breast.,biopsy from left breast.,received 3 grey white linear cores measures 1 to 1.5cm entire tissue processed.,section studied from cores of tract parenchyma shows extensive areas of desmoplasia and fibrosis with a foci showing invasive neoplasm arranged in nests and cords. the cells are pleomorphic with scant eosinophilic cytoplasm and pleomorphic hyperchromatic nuclei. occasional cells show prominent nucleoli.,left breast lump :invasive neoplasm nst grade 2. modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 .........
MR1904041,right breast lump carcinoma breast.,biopsy from left breast lump.,received grey white linear cores 3 measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in cords and abortive tubules. the cells have round hyperchromatic nuclei and moderate cytoplasm. stroma shows desmoplasia.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1904042,left breast lump carcinoma breast.,left breast lump biopsy.,received 4 grey white linear cores measures measures 1 to 1.5cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in cords and clusters. the lesional cells are round to oval having hyperchromatic nuclei scant cytoplasm. stroma shows desmoplasia. mitoses 5 6 10 hpf,left breast lump biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 .........ductal carcinoma in situ cribriform and comedo type seen.
MR1904047,right breast lump carcinoma breast.,biopsy from right breast lump.,received grey white linear cores measures 0.8 to 0.5cm. entire tissue processed.,sections studied from linear cores of fibrocollagenous tissue shows scattered small lymphocytes with histiocytes with tiny foci showing clusters of atypical cells.,right breast lump :solitary focus of atypical cells .tissue not representative.kindly repeat the biopsy.
MR1904077,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,the section shows linear cores of tissue showing large cores of hyalinisation with tumor cells infiltrating in nests sheets and cords. the tumor cells are round to ovoid to plasmacytoid with enlarged ovoid nuclei and moderate amount of cytoplasm.,biopsy from right breast lump. invasive carcinoma nst nuclear grade 2.
MR1904080,left breast lump carcinoma breast.,left breast lump core biopsy.,received 4 grey white linear cores measures 1 to 1.5cm entire tissue processed.,section shows linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in tubules nests and cords. the cells have round hyperchromatic nuclei with moderate cytoplasm. stroma shows desmoplasia.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1904105,right breast lump carcinoma breast.,biopsy from right breast lump.,received grey white linear cores measures 0.5 to 0.8cm. entire tissue processed.,section studied shows tiny fragments of fibrous tissue harboring a small lesion arranged in papillae with fibrovascular core. the papillae are lined by columnar cells with basally placed dark nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. stroma shows fibrosis.,right breast biopsy :scant volume of fibrous tissue showing features of papillary lesion. needs larger tissue to ascertain nature of the lesion.
MR1904107,local recurrence.,left breast biopsy.,received 3 grey white linear cores measures 0.5 to 0.8cm. entire tissue processed.,section studied shows cores of fibrous tissue shows infiltrative lesion arranged in sheets and cords. the cells are oval have moderately pleomorphic hyperchromatic nuclei prominent nucleoli and moderate amount of eosinophilic cytoplasm. mitotic figures are discerned. stroma shows desmoplasia areas of necrosis and inflammatory infiltrate composed of neutrophils and lymphocytes.,left breast biopsy : invasive carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1904110,left breast lump.,left breast lesion biopsy.,received 3 linear cores measures 1to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in cords and nests. the lesional cells are round to oval having hyperchromatic nuclei scant cytoplasm. cells exhibit moderate nuclear pleomorphism. mitosis 5 6 10hpf. stroma shows desmoplasia.,left breast lesion biopsy. invasive ductal carcinoma grade 2 modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1904127,right breast lump carcinoma breast.,right breast lump biopsy.,receive grey white 4 linear cores measures 1to 1.5cm. entire tissue processed.,sections shows linear cores of tumor composed of round to polygonal cells arranged as nests and trabeculae. the tumor cells show moderate pleomorphism with high n:c ratio hyperchromatic nucleus and moderate cytoplasm. mitosis are discerned. stroma shows desmoplasia and inflammatory infiltrate.,right breast lump biopsy. invasive carcinoma nst grade 3.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 .........
MR1904130,left breast lump intermediate lesion.,biopsy from left breast lump.,received three grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows fibrofatty tissue infiltrated by neoplastic cells arranged in small clusters abortive tubules and nests. the cells have round hyperchromatic nuclei and moderate amount of cytoplasm.,left breast lump :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(2+2+2).
MR1904140,right breast lump carcinoma breast.,right breast lump biopsy.,received 3 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section show linear core of tumor composed of polygonal cells arranged as nests and sheets. these cells show high n:c ratio vesicular nucleus prominent nucleolus with moderate pleomorphism. mitosis are 6 8 hpf. stroma shows desmoplasia.,right breast lump biopsy. invasive carcinoma nst grade 2. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1904153,left breast mass.,left breast mass biopsy.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring invasive neoplasm arranged in nests and glandular pattern. the cells are round to polygonal with moderate eosinophilic cytoplasm round hyperchromatic nucleus prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia and inflammatory cells.,left breast mass biopsy. :invasive carcinoma nst grade 3. modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 .........
MR1904155,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 1 to 1.3cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in tubules nests and cords. the cells have round hyperchromatic nuclei and moderate eosinophilic cytoplasm.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(2+2+2).
MR1904159,left breast lump biopsy.,left breast lump biopsy.,received 4 grey white linear cores measures 1to 1.5cm. entire tissue processed.,section shows multiple linear cores of tissue harboring infiltrating lesion arranged in sheets and cords. the lesional cells are round to oval having hyperchromatic nuclei scant cytoplasm. the cells exhibit moderate nuclear pleomorphism. stroma sheets desmoplasia lymphocytic infiltrate mitosis 5 6 10hpf.,left breast lump biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1904165,carcinoma left breast.,a)left breast wide local excision b)blue +hot nodec)hot node,a) received skin cover soft tissue bits measures 9x7x3.5cm.skin ellipse measures 5x2.5cm.cut surface shows grey white ill defined forms lesion measures 2x1.5x1.5cm.distance from marginssuperior margin :1.5cminferior margin :1cmmedial margin :1.5cmlateral margin :1.5cmdeep margin :0.8cmb)received multiple fibrofatty tissue bits tissue altogether measures 5x4x3cm 6 nodes identified.c)received 2 lymph nodes largest measures 1x0.5x0.5cm. cut surface fatty infiltration.,sections studied from breast parenchyma harbours invasive carcinoma arranged in tubules cords and nests. the cells are markedly pleomorphic with scant cytoplasm and hyperchromatic irregular nuclei. brisk atypical mitosis seen. extensive solid cribriform comedo type. ductal carcinoma in situ present. stroma shows sclerosis with lymphoplasmacytic infiltrate.,a)left breast wide local excision :invasive carcinoma nos.grade 2modified bloom richardson score is 7 3+2+2.tumor measures 1.5cm.invasive carcinoma measure 1cm.ductal component measure 0.5cm.lymphovascular invasion is not identified.perineural invasion is not identified.sentinel lymph nodes:lymph node 6 identified metastasis 0(0 6).pathological stage :ypt1snn0.
MR1904198,case of right breast carcinoma. post lumpectomy,a) right breast post lumpectomy wide excision.b) sentinel hot node.c) sentinel blue+hot node.d) revised inferior margin.,a)fresh tissue received : yeslaterality : right specimen orientation : orientated specimen size : 5.5x5.5x5cm skin dimensions : 3x1cm scar measures :1.5x0.5cm.cut surface ill defined lesion measures 1.8x1.4x1.4cm.distance from margins:superior margin :1.5cminferior margin : 0.1cmmedial margin : 2.0cmlateral margin : 1.0cmdeep margin :1.0cmb) received 1 lymph node measures 0.5x0.5x0.5cm.c) received fibrofatty tissue measures 1.5x1x1cm. isolated 1 lymph node measures 0.4x0.3x0.3cm.d) received fibrofatty tissue measures 2.5x1x1cm.,tumor bed: residual invasive carcinoma composed of tubules and nests of pleomorphic cells with moderate atypia in a desmoplastic stroma. adjacent areas show solid cribriform and comedo type high grade ductal carcinoma in situ.,a) right breast post lumpectomy wide excision:residual invasive carcinoma nst.tumor measures 1.8cm in greatest dimensioninvasive carcinoma measures 1cm.modified bloom richardson score is 3+2+3 8 9 grade 3.high grade ductal carcinoma in situ(dcis) that measures 0.5cm and is of solid cribriform and comedo type lymphovascular invasion not present.perineural invasion not identifiedall resected margins are free of tumor.b) sentinel (hot ) node : 1 node is free of tumor (0 1).c) sentinel blue+hot node: 1 node is free of tumor (0 1).d) revised inferior margin : is free of tumor
MR1904199,right breast lump.,right breast lump biopsy.,received 3 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in sheets nests cords. the lesional cells are round to oval having hyperchromatic nuclei scant cytoplasm. the cells exhibit moderate nuclear pleomorphism mitosis 10 12 10hpf.,right breast lump biopsy :invasive ductal carcinoma grade 3.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 .........
MR1904206,right breast lump.,right breast mass biopsy.,received grey white linear cores measures 1to 1.5cm. entire tissue processed.,section show multiple linear of breast parenchyma harboring infiltrating lesion arranged in cords and nests. the cells are round to oval having hyperchromatic nuceli moderate cytoplasm. the cells exhibit mild nuclear pleomorphism. mitosis 5 6 10hpf stroma shows desmoplasia.,right breast mass biopsy :invasive carcinoma with lobular features grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 1mitotic figures : 2 6 9 .........
MR1904216,right breast lump carcinoma breast.,biopsy from right breast.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows breast parenchyma harboring an invasive neoplasm in nests and loosely arranged cords. the cells show moderate eosinophilic to clear cytoplasm hyperchromatic nuclei and prominent nucleoli. adjacent ducts shows extensive solid and comedo type high grade ductal carcinoma in situ. there is dense intratumoral lymphocytic infiltrate.,right breast lump biopsy :invasive carcinoma nst with high grade ductal carcinoma in situ. grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1904221,carcinoma left breast.,biopsy from left breast.,received 3 linear cores measures 1 to 1.5cm. entire tissue processed.,sections show linear cores of fibrous tissue harboring an infiltrative lesion with cells arranged in sheets nests and clusters. the cells have scant to moderate cytoplasm pleomorphic hyperchromatic nuclei with some having prominent nucleoli. surrounding stroma is desmoplastic. areas of hemorrhage seen.,left breast biopsy :invasive carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1904223,left breast lump .,biopsy from left breast.,received grey white linear cores measures 1to 1.5cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm composed of nests and secularist of tumor cells with moderate cytoplasm hyperchromatic nuclei with prominent nucleoli. adjacent ducts show solid type ductal carcinoma in situ (intermediate grade).,left breast lump biopsy :invasive carcinoma nst with ductal carcinoma in situ. modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1904243,left breast lump carcinoma breast.,left breast lump biopsy.,received grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section cores of fibroadepose tissue harboring an invasive neoplasm in nests and sheets. the tumor cells show moderate eosinophilic to clear cytoplasm pleomorphic nuclei with prominent nucleoli.,left breast lump biopsy :invasive carcinoma nst grade3modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 .........
MR1904309,right breast lump neoplastic.,right breast lump core biopsy.,received 4 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,the section shows fragmented linear cores of tissue exhibiting tumor infiltrating in sheets and vague papillae. the tumor cells are round to ovoid with high n:c ratio enlarged ovoid nuclei and moderate amount of cytoplasm. intervening stroma is desmoplastic.,right breast lump core biopsy :invasive carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1904320,left breast mass.,left breast mass biopsy.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,the section show linear cores of tissue exhibiting tumor infiltrating in nests and sheets. the cells have moderate cytoplasm round to oval hyperchromatic nuclei with inconspicuous nuclei. atypical mitosis discerned (5 6 10hpf) surrounding stroma is desmoplastic.,left breast mass biopsy :invasive carcinoma nst grade 2. modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1904324,right breast lump.,right breast lump biopsy.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in cords and nests. the cells are round to oval having hyperchromatic nuclei and scant cytoplasm. the cells exhibit moderate nuclear pleomorphism. mitosis 2 3 10hpf stroma shows lymphocytic infiltrate.,right breast biopsy :invasive carcinoma with lobular features grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1904391,carcinoma right breast lump.,right breast lump biopsy.,received multiple grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section studied shows breast parenchyma harboring lesion arranged in nests trabeculae and few papillary fronds also. lesional cells are large with pleomorphic round to oval hyperchromatic nuclei inconspicuous nucleoli moderate eosinophilic cytoplasm. mitotic figures (4 5 10hpf) are discerned. stroma shows desmoplasia with lymphocytic infiltrate.,right breast lump biopsy.invasive carcinoma nst grade 1.modified bloom richardson score is 5 9.tubular formation 2nuclear pleomorphism 2mitotic figures 1 5 9
MR1904398,right breast lump.,right breast lump wide local excision.,received 1 specimen 8 slides 8 blocks labelled as : b 94 19.,sections studied from breast parenchyma harbors an invasive neoplasm arranged predominantly in thin cords in indian file arrangement along with lobular carcinoma in situ. low grade solid type. the cells are mildly pleomorphic with scant cytoplasm and hyperchromatic nuclei stroma shows extensive sclerosis. lobular carcinoma in situ represents 50 of the tumor in to sections submitted. one of the resected margins show tumor infiltration.,right breast lump wide local excision. invasive carcinoma with lobular features grade 1.modified bloom richardson score is 5 9tubule formation : 3nuclear pleomorphism : 1mitotic figures : 1 5 9 .........lobular carcinoma in situ represent 50 low grade.lymphovascular invasion not identified.perineural invasion not identified.
MR1904427,left breast lump carcinoma breast.,left breast lump biopsy.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged in nests and cords. the cells have hyperchromatic nuclei scant cytoplasm. the cells exhibit moderate nuclear pleomorphism. mitosis 5 6 10hpf. stroma shows hyalinisation.,left breast lump biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1904437,right breast lesion carcinoma breast.,biopsy from right breast lesion.,received 4 grey white linear cores measures 1to 1.5cm. entire tissue processed.,section shows fibrocollagenous tissue infiltrated by neoplastic cells arranged in abortive tubules nests and cords. the cells have round hyperchromatic nuclei and moderate cytoplasm. mitosis is discerned.,biopsy from right breast lesion :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1904442,right breast lump carcinoma breast.,biopsy from right breast lump.,received 3 grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section studied from linear cores of lesional tissue composed of tumor cells arranged in cords trabeculae and nests. the cells are mildly pleomorphic having scant cytoplasm and large hyperchromatic nuclei and atypical mitosis seen. stroma shows dense desmoplasia.,right breast lump biopsy :invasive carcinoma nst. grade iimodified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 .........
MR1904444,left breast lump.,left breast lesion biopsy.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring infiltrating lesion arranged nests and sheets. the cells are round to oval having hyperchromatic nuclei and scant cytoplasm mitosis seen. stroma shows hylinization.,left breast lesion biopsy :invasive carcinoma with papillary fragments grade 1modified bloom richardson score is 5 9tubule formation : 3nuclear pleomorphism : 1mitotic figures : 1 5 9 .........solid ductal carcinoma in situ present.
MR1904445,right breast lump.,biopsy from right breast mass.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections studied from linear cores of lesional tissue composed of neoplastic cells seen in sheets and indian file pattern. the cells are pleomorphic with scant cytoplasm and irregular hyperchromatic nuclei. stroma shows dense desmoplasia with lymphomononuclear infiltrate.,biopsy from right breast mass:invasive carcinoma nst.modified bloom richardson sore is (3+3+2) 8 9
MR1904457,left breast lump carcinoma breast.,biopsy from left breast lump.,received 3 grey white linear cores measures 0.5 to 1.3cm. entire tissue processed.,sections studied from linear cores of breast parenchyma harbors invasive neoplasm arranged in tubules nests and cords. the cells are pleomorphic with scant cytoplasm and irregular hyperchromatic nuclei. occasional atypical mitosis seen. stroma shows extensive desmoplasia.,biopsy from left breast lump:invasive carcinoma nos grade ii.modified bloom richardson score is 7 9.tubular formation 2nuclear pleomorphism 3mitotic activity 2 7 9
MR1904467,carcinoma right breast,a)right sentinel lymph nodes.b)right mastectomyc)right level 1 2d)right level 3,a) received single fibrofatty tissue measures 2x1x0.5cmisolated 1 lymph node measures 1.5x1x0.5cmb)received in : formalinprocedure :mastectomy laterality : righttotal dimensions :medial to lateral :15cm superficial to deep :5cm superior to inferior:15cmskin ellipse : 13x8cm nipple : unremarkable scar surgical defect :not seen tumor : grossly no tumor identified specs of calcification in the 3 clock position measures 1x0.5x0.5cmmargin of tumor : ill defined deep margin :1cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail :10x8cmc) received multiple fibrofatty tissue measures 8x8x3cm.largest lymph node measures 3z1.5z1cm.d) received fibrofatty tissue measures 3x2x1cm.,section studied from breast parenchyma shows only dense fibrous stroma with sclerosis amidst benign ductal tissue. no residual invasive neoplasm present.,b)right mastectomy.histological type:no residual invasive neoplasm ductal carcinoma in situ. posterior resection margin is unremarkable.nipple and areola is unremarkable.a) right sentinel lymph node1 1 lymph node isolated and metastasis is seen 1 (1 1).extranodal extension identified.c)right level 1 2 lymph nodes :7 metastasis is seen in 0(0 7).d) right level 3 lymph node :3 metastasis is seen in 0(0 3)pathological stage : ypt0snn1 summary:no residual viable invasive neoplasm right mastectomy lymphnode status:a) right sentinel nodes :1 1.c) right level 1 2 lymph node :0 7.d) right level 3 lymph node :0 3.total lymph node:1 11extranodal extension identified.
MR1904474,left breast lump.,left breast lump biopsy.,received 7 linear cores measures 1to 1.5cm. entire tissue processed.,sections studied shows cores of breast parenchyma harbors infiltrative lesion arranged in cords and clusters. the cells are oval have moderately pleomorphic hyperchromatic nuclei few showing prominent nucleoli and moderate amount of eosinophilic cytoplasm. mitotic figures are discerned. foci of ductal carcinoma in situ with comedo necrosis is seen. stroma shows desmoplasia.,left breast biopsy : invasive carcinoma nst grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1904475,left breast mass carcinoma breast.,left breast mass biopsy.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,the sections shows linear cores of tissue showing areas of sclerosis and tumor infiltrating in nests and islands. the tumor cells are round to ovoid having enlarged hyperchromatic nuclei and moderate amount of cytoplasm. intervening desmoplasia is seen.,left breast mass biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1904482,left breast mass carcinoma left breast.,left breast mass biopsy.,received 3 grey white linear cores measures 1 1.5cm. entire tissue processed.,section studied shows cores of fibrous tissue harbors infiltrative lesion arranged in sheets nests and cords. the cells are oval have pleomorphic hyperchromatic nuclei conspicious nucleoli and moderate amount of eosinophilic cytoplasm. mitotic activities is discerned. stroma shows desmoplasia.,left breast mass biopsy:invasive carcinoma grade 2.modified bloom richardson score is 7 9(3+2+2).
MR1904504,known case of carcinoma right breast .left supraclavicular node.,biopsy from left supraclavicular node.,received 6 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section studied shows cores of fibrous tissue harbors tumor arranged in nests and sheets. the cells are oval have moderately pleomorphic hyperchromatic nuclei inconspicuous nucleoli. few shows prominent nucleoli and moderate amount of eosinophilic cytoplasm. mitotic figures are discerned. stroma shows desmoplasia.,left supraclavicular node biopsy :metastatic carcinoma in known case of carcinoma breast.
MR1904525,carcinoma right breast.,right breast lump biopsy.,received 3 grey white linear cores measures 0.5to 0.8cm. entire tissue processed.,sections studied from multiple bits of lesional tissue harbors tumor cells arranged in nests and trabecular in pools of mucin. the cells are round to oval with scant cytoplasm and hyperchromatic irregular nuclei.,right breast lump :mucinous carcinoma. nuclear grade 2.
MR1904526,left breast lump.,biopsy from left breast.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows cores of breast parenchyma shows infiltrative arranged in sheets nests cords and occasional tubules. the cells have moderately pleomorphic hyperchroamtic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. mitotic figures are discerned. intervening stroma shows desmoplasia and lymphocytic aggregates.,biopsy from left breast:invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9.tubule formation 3nuclear pleomorphism 2mitotic activity 1 6 9
MR1904601,mass in right breast 1 2 0 clock position birads iv lesion for biopsy.,right breast biopsy.,received 4 grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section studied shows cores of breast parenchyma harbours infiltrative lesion arranged in nests sheets and trabeculae. the cells are oval have mild to moderately pleomorphic nuclei prominent nucleoli and moderate amount of eosinophilic cytoplasm. mitotic figures are discerned. stroma shows desmoplasia.,right breast biopsy :invasive carcinoma nst grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1904620,case of left breast carcinoma.,a) left breast wide excision.b)sentinel blue node.c)sentinel blue+hot node.,a) skin covered globular mass measures 7.4x5x3cmskin measures 4.3x0.4cm tumor measures 1.5x1.2x0.9cm.distance from margin:superior margin :1.5cminferior margin :1.6cmmedial margin :2.2cmlateral margin :3.2cmdeep margin :1cmb)received fibrofatty tissue measures 2x1x1cm isolated 2 nodes.largest one measures 0.5x0.5x0.5cm. c)received fibrofatty tissue measures 2x2x1cm isolated 1 node measures 0.7x0.5x0.5cm.,section studied from breast parenchyma harbors invasive neoplasm arranged in cords and nests. the cells are mildly pleomorphic having scant cytoplasm and hyperchromatic nuclei mitosis3 4 hpf. stroma shows lymphoplasmacytic infiltrate with sclerosis and myxoid change. foci showing compressed benign ductal epithelial cells seen.ductal carcinoma in situ component cribriforom and solid ductal carcinoma in situ.,left breast wide local excision:invasive carcinoma nosmodified bloom richardson score 2+1+1 4 grade 1.tumor measures 1.5cm in greatest dimension.ductal carcinoma in situ measure 0.5cm.all margins are free of tumor.lymphovascular invasion nor identified.sentinel lymph nodes 2 lymph nodes metastasis 0(0 3)pathological stage:pt1pn0.
MR1904621,carcinoma right breast.,right modified radical mastectomy.,received in : formalinprocedure : modified radical mastectomy laterality :righttotal dimensions :medial to lateral :17cm superficial to deep :4.5cm superior to inferior:19cm nipple : normal scar surgical defect :absenttumor : singletumour size :3x2.5x2cm location of tumor : upper outer quadrantmargin of tumor : ill defined deep margin : 1.5cmmuscle : absentadjacent breast : fibrofatty tissueaxillary tail : 10x7x2cm,section studied from breast parenchyma harbors invasive neoplasm arranged in tubules sheets and nests. the cells are pleomorphic with abundant eosinophilic cytoplasm and hyperchromatic nuclei atypical mitosis 7 8 10hpf . stroma shows dense sclerosis. foci showing cribriform ductal carcinoma in situ and solid ductal carcinoma in situ present.,right modified radical mastectomy:histological type:invasive carcinoma nos.grade:2tumor measures maximum dimension 3 cm.invasive component measures 2 cm.ductal carcinoma in situ measures 1 cm.modified br score is 6 9tubule formation: 2 nuclear pleomorphism:2 mitotic figures:2 ductal carcinoma in situ cribriform solid. lymphovascular invasion is identified.perineural invasion not identified. posterior resection margin is free of tumor.nipple and areola is free of tumor.lymph nodes: 10 lymph nodes metastasis: 1(1 10).pathological stage:pt1pn1summary:invasive carcinoma right modified radical mastectomy.grade :2.lymph node status :1 10 perinodal spread spread absent.
MR1904658,left breast lump carcinoma breast.,biopsy from left breast lump.,received grey white linear cores measures 1 to 1.4cm. entire tissue processed.,section studied from linear cores ofbreast parenchyma harbors invasive neoplasm arranged in tubules nests cords and scattered isolated cells. the cells are pleomorphic with s scant cytoplasm and large hyperchromatic irregular nuclei. brisk atypical mitosis present. stroma shows extensive desmoplasia.,biopsy from left breast lump:invasive carcinoma nos grade iiimodified bloom richardson score is 8 9tubular formation 3.nuclear pleomorphism 3mitotic activity 2 8 9
MR1904699,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections studied from linear cores of breast parenchyma composed of malignant glands arranged in cords nests and vague illdefined tubules lined by cells which cuboidal to oval with scant cytoplasm and hyperchromatic irregular nuclei. stroma shows focal myxoid areas with desmoplasia.,biopsy from left breast lump:invasive carcinoma nos grade ii.modified bloom richardson score is 7 9.tubular formation 2nuclear pleomorphism 3mitotic activity 2 7 9
MR1904720,left breast lesion birads iii b.,biopsy from left breast lesion.,received 3 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows 2 cores of breast tissue with ducts showing solid and cribriform type ductal carcinoma insitu intermediate grade. few hemorrhagic fragments show nests of tumor cells embedded. stroma shows focal desmoplastic myxoid change.,left breast lesion.suggestive of ductal carcinoma in situ (intermediate grade).note : suggest repeat biopsy if clinically deemed necessary.
MR1904739,left breast lump neoplastic.,biopsy from left breast lump.,received 3 grey white linear cores measures 2cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in sheets and nests. the cells are oval have moderately pleomorphic hyperchromatic nuclei inconspicuous cytoplasm. mitotic figures are discerned. stroma shows desmoplasia.,biopsy from left breast lump :invasive ductal carcinoma grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1904741,left breast lump neoplastic.,biopsy from left breast lump.,received 3 grey white linear cores measures 1.2cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in diffuse sheets nests and tubules. the tumor is composed of oval cells have moderately pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderately amount of cytoplasm. stroma shows desmoplasia areas of necrosis. stroma dense lymphocytic infiltrate.,left breast lump biopsy :invasive ductal carcinoma grade 2modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1904759,right breast lump neoplastic.,right breast lump biopsy.,received 3 grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section studied from cores of breast parenchyma harbors infiltrative lesion arranged in tubules nests cords and single scattered. the cells are oval have moderately pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. stroma show desmoplasia. ductal carcinoma in situ component is noted.,right breast lump biopsy :invasive carcinoma nst grade 1modified bloom richardson score is 5 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 1 5 9 .........
MR1904781,right breast mass.,biopsy from right breast mass.,received grey white linear cores measures 1.5 to 2cm. entire tissue processed.,the section shows linear cores of tissue exhibiting tumor infiltrating in nests. cords and trabecular pattern. the tumor cells are round to cuboidal with enlarged ovoid nuclei and moderate amount of cytoplasm. surrounding desmoplastic reactive is seen.,right breast mass :invasive ductal carcinoma grade 2modified bloom richardson score is (3+2+1) 6 9
MR1904806,left breast mass carcinoma breast.,biopsy from left breast mass.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in nests. the cells show moderate pleomorphism hyperchromatic nuclei and prominent nucleoli. few ducts show solid type ductal carcinoma in situ. stroma is desmoplastic.,left breast mass biopsy :invasive carcinoma nst grade iimodified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1904823,right breast mass carcinoma breast.,right breast mass.,received 5 grey white linear cores measures 1.5 to 2cm. entire tissue processed.,the section shows tumor cores of tissue exhibiting scant tumor infiltrating in cords and nests. the tumor cells are round to polygonal with increased n:c ratio enlarged hyperchromatic nuclei and moderate cytoplasm. surrounding desmoplasia is seen.,right breast mass. invasive ductal carcinoma grade 2.modified bloom richardson score is (3+2+1) 6 9.
MR1904846,right breast mass carcinoma breast.,biopsy from right breast mass.,received 4 grey white linear cores measures 0.5 to 2cm. entire tissue processed.,section studied shows cores of fibrous tissue harbors infiltrative lesion arranged in nests trabeculae and cords. the cells are oval have moderately pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. mitotic figures are discerned. stroma shows desmoplasia.,right breast biopsy :invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1904863,right breast mass carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measures 1 to 1.5cm entire tissue processed.,the section shows linear cores of breast parenchyma showing tumor infiltrating in nests and occasional tubules. micropapillary pattern of invasion is noted. the tumor cells are round to ovoid with enlarged ovoid hyperchromatic nuclei and moderate amount of cytoplasm. intervening desmoplasia is noted.,right breast biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1904864,right breast mass carcinoma breast.,biopsy from right breast mass.,received 4 grey white linear cores measures measures 1 to 1.5cm. entire tissue processed.,sections studied from linear cores of breast parenchyma harbors invasive neoplasm arranged in sheets trabecular and cords. the cells are pleomorphic with scant cytoplasm and hyperchromatic irregular nuclei. brisk atypical mitotic seen. stroma shows sclerosis with lymphomononuclear infiltrate.,right breast mass trucut biopsy. invasive carcinoma nos grade ii.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1904865,left breast solid mass.,biopsy from left breast mass.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,the section shows linear cores of breast parenchyma showing tumor infiltrating into sheets and nests. the tumor cells are round to ovoid having high n:c ratio hyperchromatic pleomorphic nuclei and moderate amount of cytoplasm. numerous mitotic figures are seen.,biopsy from left breast mass:invasive ductal carcinoma grade 3 modified bloom richardson score is 8(3+2+3).
MR1904866,right breast mass carcinoma breast.,biopsy from right breast mass.,received multiple fragment grey white linear cores measures 0.5 to 1cm. entire tissue processed.,sections studied from linear cores of breast parenchyma harbors invasive neoplasm arranged in cords and trabecular. the cells are mildly pleomorphic with scant vacuolated cytoplasm and hyperchromatic irregular nuclei. stroma shows extracellular mucin with few focal areas showing sclerosis.,right breast mass trucut biopsy :mucinous carcinoma.grade i. modified bloom richardson score is 4 9tubule formation : 2nuclear pleomorphism : 1mitotic figures : 1 4 9 .........
MR1904873,right breast mass.,right breast mass biopsy.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of fibro adipose tissue harboring an invasion neoplasm in nests and cords composed of tumor cells with moderate cytoplasm increased n:c ratio pleomorphic nuclei with hyperchromasia .focus of calcification noted.,right breast mass biopsy :invasive carcinoma nst.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1904918,right breast mass carcinoma breast.,right breast mass.,received 4 grey white linear cores measures 1 to 2cm. entire tissue processed.,the section shows linear cores of tissue exhibiting large areas of necrosis with scant tumor infiltrating in nests and occasional tubules. the tumor cells are round to cuboidal with increased n:c ratio enlarged ovoid nuclei and moderate amount of cytoplasm with intervening desmoplasia.,right breast mass biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1904963,left breast mass carcinoma breast.,biopsy from left breast mass.,received 4 grey white linear cores measures 0.5 to 1.5cm. entire tissue processed.,sections studied from linear cores of breast parenchyma harbors invasive neoplasm arranged in tubules nests and scattered isolated cells. the cells are scant cytoplasm with irregular hyperchromatic nuclei. occasional cells show prominent eosinophilic nucleoli. stroma shows desmoplasia with focal mucin and scattered lymphoplasmacytic infiltrate.,left breast mass biopsy :invasive carcinoma nos grade iimodified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 .........
MR1904984,right breast mass.,right breast mass biopsy.,received 4 linear cores measures 1 to 1.5cm. entire tissue processed.,received linear cores of tissue exhibiting tumor infiltrating in tubules and nests. individual cells are round to cuboidal having enlarged hyperchromatic nuclei and moderate amount of cytoplasm. intervening desmoplastic stroma seen.,right breast mass biopsy :invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
MR1904988,carcinoma left breast ct4bn1m0,left breast left modified radical mastectomy.,received in : formalinprocedure : modified radical mastectomy laterality : lefttotal dimensions :medial to lateral : 14cm superficial to deep :3.5cm superior to inferior:8cmskin ellipse : 9.5 x 6 cm shows nodular lesion measures 2 x 1.5 cm cut surface tumor reaching upto the skin. no ulceration is seen. nipple : unremarkable tumor : singletumour size : 2.5 x 2 x 2 cm location of tumor : upper outer quadrantmargin of tumor : ill defined deep margin :1cmmuscle : 4.5x4cmadjacent breast : fibrofatty tissueaxillary tail :7.5x6x2cm,section from breast shows an invasive neoplasm arranged in tubules clusters and cords. the cells have round vesicular nuclei prominent vesicular nucleoli moderate cytoplasm. ductal carcinoma in situ is seen.( solid cribriform and comedo pattern).,left modified radical mastectomy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2). tumor is located in upper outer quadrant. tumor measures maximum dimension 2.5 cm. tumor extends upto the dermis without ulceration. ductal carcinoma in situ is seen solid cribriform comedo pattern with intermediate nuclear grade. lymphovascular invasion is identified. perineural invasion is not seen. posterior resection margin is free of tumor. nipple and areola is free of tumor. lymph nodes: eighteen out of twenty two lymph nodes shows metastatic tumor deposits with extranodal extension(18 22). size of the largest tumor deposit measures 1.2 cm in greatest dimensionpathological stage: pt2n3a
MR1905034,left breast lump neoplastic.,biopsy from left breast.,received multiple grey white linear cores measures 1 to 2cm. entire tissue processed.,section shows cores of fibrous tissue harbors infiltrative lesion arranged in diffuse sheets. the cells are oval have pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. mitotic figures are discerned. stroma shows desmoplasia.,biopsy from left breast:invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9.tubular formation 3nuclear pleomorphism 2mitotic activity 1 6 9
MR1905036,right breast mass carcinoma breast.,right breast mass.,received 4 grey yellow linear core measures 1 to 2cm. entire tissue processed.,section show breast parenchyma harboring an invasive neoplasm composed of nests and aggregates of pleomorphic cells with increased n:c ratio hyperchromatic nuclei moderate eosinophilic cytoplasm. there is peritumoral inflammatory cell infiltrate.,right breast mass :invasive carcinoma nst.modified bloom richardson score is 7 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 .........
MR1905038,carcinoma right breast.,a) sentinel blue nodes.b)right breast wide local excision.c)revised superior margin.d)axillary lymph node dissection.,a)received 3 fibrofatty tissue largest measures 3.5x3x1cm.isolated 3 lymph nodes.b)received globular mass measures 5.5x4.5x2.6cm.skin ellipse measures 3.2x1.6x6cm. cut surface tumor measures 1.8x1.5x1cm.distance from margins:superior margin :0.7cminferior margin :1.5cmmedial margin :1.5cmlateral margin :1.6cmdeep margin :1.5cmc)received fibrofatty tissue measures 2.2x1x0.5cm.d) received fibrofatty tissue measures 10x9x2cm.largest lymph node measures 3x2x1cm.,section studied from breast parenchyma harbors invasive neoplasm arranged in trabecular nests and cords. the cells are mildly pleomorphic having scant cytoplasm and vesicular nuclei. occasional cells show prominent nucleoli. stroma shows dense sclerosis. few ducts are showing mild hyperplasia and fibrosis cystic change.,right breast wide local excision:invasive caricnoma nos.modified bloom richardson score 6(2+2+2) grade 2.tumor measures 1.8cm in its greatest dimension.inferior medial lateral margin are free of tumor superior margin is 0.2cm away from tumor.revised superior margin: free of tumor.sentinel lymph nodes :3 nodes metastasis 3(3 3).axillary lymph node :20 nodes metastasis 0(0 20).summary:right breast wide local excision:invasive carcinoma nos.grade 2lymph node status:sentinel lymph nodes :3 3.axillary lymph node :0 20.total lymph nodes :3 23.
MR1905051,left breast mass carcinoma breast.,biopsy from left breast mass.,received 3 4 grey brown linear cores measures 0.2 to 0.7cm. entire tissue processed.,sections shows cores of breast tissue harboring a malignant neoplasm in sheets and nests. the cells show moderate cytoplasm pleomorphic nucleoli with hyperchromasia. there is extensive necrosis.,left breast mass biopsy :invasive carcinoma nst grade iii. modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 .........
MR1905053,right breast mass.,biopsy from right breast mass.,received multiple grey white linear cores measures 0.2 to 1.2cm. entire tissue processed.,section shows linear cores of tissue exhibiting tumor infiltrating in nests and cores and cribriform pattern. the tumor cells are round to cuboidal having enlarged hyperchromatic nuclei and moderate amount of cytoplasm. intervening desmoplasia is noted.,biopsy from right breast mass:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1905073,carcinoma right breast modified radical mastectomy done in 1994.,scar site ulcer wide excision.,received excision specimen measurinf 7.9x6.5x1cm showing skin with an ulcer .ulcer measures 2.9x2.6x0.5cm the ulcer is punched out with over hanging margins and shallow edges.the floor of ulcer is grey white and edematous surrounding skin is unremarkable.distance of the ulcer from the margins:superior margin 1.3cm.inferior margin 0.3cm.medial margin 0.4cm.lateral margin 2.9cm.deep margin 0.4cm.,section from the ulcer show extensive necrosis inflammatory infiltrate granulation tissue with plump endothelial cells and fibrosis. adjacent skin shows suture material in the subjacent stroma.,scar site ulcer wide excision:chronic ulcer with inflammation and fibrosis.no evidence of neoplasia .all resected margins are unremarkable.overlying skin is unremarkable.
MR1905110,left breast lump carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 1 to 2cm. entire tissue processed.,section shows cores of fibrocollagenous tissue harboring an invasive neoplasm in sheets composed of pleomorphic cells with increased n:c ratio moderate cytoplasm hyperchromatic nuclei and increased mitosis. areas of necrosis and calcification also noted. there is dense inflammatory cell infiltrate around the tumor.,biopsy from left breast lump:invasive carcinoma nst grade iii.modified bloom richardson score is 3+2+3 8 9.
MR1905137,left breast mass.,biopsy from left breast.,received multiple grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section studied shows cores of breast parenchyma harbours lesion arranged in cords trabeculae and nests. the cells are oval have pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. mitotic figures are discerned. stroma shows desmoplasia.,biopsy from left breast:invasive carcinoma with lobular features nuclear grade 2.modified bloom richardson score is (3+2+1) 6 9.
MR1905162,left breast lump neoplastic.,biopsy from left breast.,received multiple grey white linear cores measures 0.5x1.5cm. entire tissue processed.,linear cores of breast parenchyma harboring a neoplasm arranged in clusters and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is desmoplastic.,biopsy from left breast:invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9.tubule formation 3nuclear pleomorphism 2mitotic activity 1 6 9
MR1905250,left breast mass carcinoma breast.,biopsy from left breast biopsy.,received multiple grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section shows linear cores of fibrofatty tissue infiltrated by neoplastic cells arranged in tubules cords and clusters. the lesional cells have round hyperchromatic nuclei and moderate cytoplasm.,biopsy from left breast biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(2+2+2).
MR1905292,right breast lump suspicious.,biopsy from right breast lump.,received multiple grey white linear cores measures 1.2 to 1.5cm. entire tissue processed.,section shows linear cores of fibrofatty tissue infiltrated by neoplastic cells arranged in clusters cords and sheets. the cells have round hyperchromatic nuclei with moderate eosinophilic cytoplasm. surrounding stroma shows desmoplasia. focal areas of necrosis noted.,biopsy from right breast lump:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1905293,right breast lump neoplastic.,biopsy from right breast lump.,received 2 grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in tubules cords and dusters. the cells have round nuclei inconspicuous nucleoli and moderate cytoplasm. ductal carcinoma in situ is seen (solid comedo pattern).,biopsy from right breast lump:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1905324,right breast lump neoplastic.,biopsy from right breast lump.,received multiple grey white to grey brown linear cores measures 1.5 to 2cm. entire tissue processed.,section shows a lesion arranged in sheets and nests. the cells are round to oval hyperchromatic nuclei scant cytoplasm. few cells with abundant clear cytoplasm. areas of necrosis. few atypical mitotic figures noted.,biopsy from right breast lump:invasive ductal carcinoma grade ii.modified bloom richardson score is 3+2+2 7 9.foci of ductal carcinoma in situ with comedonecrosis seen.
MR1905374,carcinoma right breast.,right breast biopsy (11 o clock position),received multiple grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section studied shows linear cores of fibrofatty tissue infiltrated by lesion arranged in sheets trabeculae cord and nested pattern. lesional cells are large with marked pleomorphic round to oval hyperchromatic nuclei conspicuous nucleoli moderate amount of eosinophilic cytoplasm. mitotic figures (3 4 hpf) are discerned. stroma shows desmoplasia with mild lymphocytic infiltrate.,right breast biopsy (11 o clock position):invasive carcinoma nst grade 3.modified bloom richardson score is 9 9.tubular formation 3nuclear pleomorphism 3mitotic figures 3 9 9
MR1905389,left breast lump neoplastic.,biopsy from left breast lump.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in sheets and large nests. the cells show moderate cytoplasm hyperchromatic nuclei with moderate atypia and increased mitosis. areas of comedo type necrosis noted.,biopsy from left breast lump:invasive carcinoma nst grade ii.modified bloom richardson score is 3+2+2 7 9areas of comedo necrosis seen.
MR1905395,left breast mass carcinoma breast.,biopsy from left breast.,received multiple grey white linear cores measures 1.5 to 2.5cm. entire tissue processed.,section studied shows linear cores of breast parenchyma with an infiltrating lesion arranged as nests. few nests show oval having pale to clear cytoplasm hyperchromatic nucleus and prominent nucleoli. few nests and cords show oval cells having moderate amount of eosinophilic cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned (6 7 10hpf). stroma is desmoplastic with areas of hemorrhage and necrosis.,biopsy from left breast:invasive carcinoma nst grade 2.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1905396,right breast mass carcinoma breast.,biopsy from right breast mass.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of breast tissue with few cores harboring an invasive neoplasm in linear cores nests and aggregates. the cells show moderate pleomorphism hyperchromatic nuclei and increased mitosis.,biopsy from right breast mass:invasive carcinoma nst grade ii.modified bloom richardson score is 3+2+2 7 9
MR1905399,right breast lump carcinoma breast.,biopsy from right breast.,received multiple grey white linear cores measures 1.5 to 2cm. entire tissue processed.,sections shows linear cores of fibrous tissue harboring an infiltrative lesion with cells arranged in cords and trabeculae. the cells have scant to moderate amount of cytoplasm and pleomorphic hyperchromatic nuclei. atypical mitosis discerned . surrounding stroma shows desmoplasia with mild lymphomononuclear infiltrate.,biopsy from right breast:invasive duct carcinoma grade ii.modified bloom richardson score is 3+2+1 6 9.
MR1905430,right breast lump carcinoma breast.,biopsy from right breast lump.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of fibro adipose tissue harboring an invasive neoplasm in sheets and large nests the cells show moderate cytoplasm round to oval hyperchromatic nuclei with moderate pleomorphism and increased mitosis. stroma is desmoplastic with peritumoral inflammation and retraction artifacts.,biopsy from right breast lump:invasive carcinoma nst grade ii.modified bloom richardson score is 3+2+2 7 9
MR1905436,left breast mass carcinoma breast.,biopsy from left breast mass.,received multiple grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section shows cores of fibroadipose tissue harboring an invasive neoplasm composed of linear cores and aggregates of tumor cells with moderate cytoplasm hyperchromatic nuclei with moderate pleomorphism and increased mitosis stroma appears desmoplastic.,biopsy from left breast mass:invasive carcinoma nst grade iii.modified bloom richardson score is 3+2+3 8 9
MR1905469,right breast mass post lumpectomy.,biopsy from right breast.,received grey white multiple linear cores measures 0.5 to 1.5cm. entire tissue processed.,section shows linear cores of breast tissue harboring a neoplasm in solid and papillary pattern composed of moderately pleomorphic cells with increased n:c ratio moderate cytoplasm hyperchromatic nuclei and prominent nucleoli. mitotic figures are discerned. the intervening stroma is scant.,biopsy from right breast:residual carcinoma grade 3.modified bloom richardson score is 8 9.tubule formation 3nuclear pleomorphism 2mitotic figures 3 8 9 (note:morphology favors solid papillary carcinoma).
MR1905473,right breast lesion carcinoma breast.,biopsy from right breast.,received multiple grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section studied shows linear cores of breast parenchyma infiltrated by lesion arranged in nests cord trabeculae. lesional cells are large with pleomorphic round to oval hyperchromatic nuclei conspicuous nucleoli moderate amount of eosinophilic cytoplasm. mitotic figures (5 6 10hpf) are discerned. stroma shows desmoplasia with mild lymphocytic infiltrate.,biopsy from right breast:invasive carcinoma nst grade 2.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic activity 2 7 9
MR1905496,left breast lump carcinoma breast.,biopsy from left breast.,received multiple grey white linear cores measures 0.5 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrous tissue with an infiltrating lesion arranged as islands cords and tubules. the cells are ovoid having moderate amount of cytoplasm hyperchromatic pleomorphic nucleus and prominent nucleoli in few. mitotic figures are discerned (12 13 10hpf). stroma is desmoplastic with mild lymphomononuclear infiltrate.,biopsy from left breast:invasive carcinoma nst grade 3.modified bloom richardson score is 9 9tubular formation 3nuclear pleomorphism 3mitotic figures 3 9 9
MR1905505,left breast mass carcinoma breast.,biopsy from left breast:,received multiple grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section studied shows linear cores of breast parenchyma with an infiltrating variable cellular lesion arranged predominantly as cords focal nests and vague tubules. the cells are ovoid having moderate amount of cytoplasm and hyperchromatic pleomorphic nucleus. mitotic figures are 2 3 10hpf. stroma shows desmoplasia and interspersed thin walled dilated blood vessels.,biopsy from left breast:invasive carcinoma nst grade 2.modified bloom richardson score is 6 9tubular formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1905516,right breast mass carcinoma breast.,right breast lump biopsy.,received multiple grey white linear cores measures 0.5 to 1.5cm. entire tissue processed.,section shows cores of breast parenchyma with an infiltrating lesion arranged as sheets and cords. the cells are monotonous medium sized with hyperchromatic nuclei moderate amount of cytoplasm. frequent mitotic figures and apoptotic bodies noted. admixed lymphocytes and plasma cells are seen. areas of necrosis noted. few cells with large and bizarre nuclei noted.,right breast lump biopsy:poorly differentiated malignancy.suggest ihc.
MR1905559,left breast lump carcinoma breast.,biopsy from left breast.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of breast parenchyma with an infiltrating lesion arranged as sheets nests and cords. the lesional cells exhibit moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. intervening stroma shows desmoplasia.,biopsy from left breast:invasive ductal carcinoma grade 2.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic activity 2 7 9
MR1905581,right breast lump carcinoma breast.,biopsy from right breast.,received multiple greywhite linear cores measures 0.3 to 1cm. entire tissue processed.,sections studied from linear cores of breast parenchyma shows tumor cells arranged in sheets.and cords the cells have moderate amount of cytoplasm and mildly pleomorphic hyperchromatic nuclei. mitosis 2 3 10 hpf. stroma shows intense desmoplasia.,invasive carcinoma nos (grade ii) poorly differentiated ductal carcinoma. lobular carcinoma.mbr score (3+2+2) 7 9.
MR1905584,right breast lump carcinoma breast.,biopsy from right breast lump.,received multiple grey white linear cores measures 1 to 2cm. entire tissue processed.,section shows cores of breast parenchyma with an infiltrating lesion arranged as nests sheets and cords. the cells exhibit moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. crush artifacts noted. intervening stroma show fibrosis and lymphocytic infiltrate.,biopsy from right breast lump:invasive carcinoma nst grade 2.modified bloom richardson score is 6 9.tubule formation 3nuclear pleomorphism 2mitotic activity 1 6 9
MR1905585,left breast mass carcinoma breast.,biopsy from left breast mass.,received multiple grey white to grey brown linear cores measures 1.5 to 2cm. entire tissue processed.,section shows cores of fibrocollagenous tissue along with skin fragments harboring an invasive neoplasm composed of nests aggregates and cords of tumor cells with abundant to moderate eosinophilic cytoplasm pleomorphic hyperchromatic nuclei and prominent nucleoli. one of the fragment is necrotic.,biopsy from left breast mass:invasive carcinoma nst grade ii.modified bloom richardson score is 7 9.tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1905619,right breast lump.,right breast lump biopsy.,received 4 grey white to grey brown linear cores measures cores 0.7 to 1.5cm. entire tissue processed.,section shows cores of breast tissue with many flatted ducts showing papillary and cribriform type ductal carcinoma in situ (high grade) and on edematous stroma. no evidence of invasive carcinoma.,right breast lump biopsy :high grade ductal carcinoma in situ (papillary and cribriform type) no evidence of invasion in thin biopsy.
MR1905626,right breast mass.,right breast mass trucut biopsy.,received 3 grey white linear cores measures 0.5 to 1.5cm. entire tissue processed.,section cores of breast tissue harboring an invasive neoplasm in cords composed of cells with hyperchromatic nuclei and moderate. tumor appears to infiltrative the fat.,right breast mass. trucut biopsy :invasive carcinoma with lobular features grade ii. modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MR1905704,right breast lump neoplastic.,biopsy from right breast lump.,received multiple grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrating neoplasm arranged in tubules nests and sheets. the lesional cells have round nuclei dispersed chromatin and moderate cytoplasm.,biopsy from right breast lump:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(2+2+2).
MR1905722,right breast lump neoplastic.,biopsy from right breast lump.,received grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section shows linear cores of fibrofatty tissue infiltrated by neoplastic cells arranged in sheets and clusters. the lesional cells have round nuclei dispersed chromatin and moderate cytoplasm. areas of necrosis is seen.,biopsy from right breast lump:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MR1905744,left breast lump carcinoma breast.,left breast lump biopsy.,received multiple grey white linear cores measures 0.5 to 2cm. entire tissue processed.,multiple cores of breast tissue harboring an invasive neoplasm in nested pattern composed of cells with abundant cytoplasm round to oval nuclei with moderate pleomorphism and increased mitosis. stroma appears hyalinized .,left breast lump biopsy:invasive carcinoma nst grade ii.modified bloom richardson score is 6 9.tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9
MR1905746,left breast mass carcinoma breast.,left breast mass biopsy.,received multiple grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in sheets cords and tubules. the neoplastic cells have ill defined cell border moderate cytoplasm hyperchromatic nuclei with a desmoplastic hyalinised stroma. few tubules show luminal secretions.,left breast mass biopsy:invasive carcinoma nst grade ii.modified bloom richardson score is 7 9.tubular formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1905781,left breast mass carcinoma breast.post lumpectomy.,left breast biopsy.,received multiple grey white linear cores measures 0.5 to 2cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in nests and sheets composed of tumor cells with increased n:c ratio moderate cytoplasm hyperchromatic nuclei and increased mitosis.,left breast biopsy:invasive carcinoma nst grade iii.modified bloom richardson score is 8 9.tubuleformation 3nuclear pleomorphism 2mitotic figures 3 8 9
MR1905795,left breast mass carcinoma breast.,left breast mass biopsy.,received multiple grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in nests aggregates. the tumor cells have abundant to moderate cytoplasm moderately pleomorphic nuclei and increased mitosis.,left breast mass biopsy:invasive carcinoma nst grade ii.modified bloom richardson score is 7 9.tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1905806,right breast mass carcinoma breast.,right breast lump biopsy.,received grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm composed of nests and aggregates of tumor cells with moderate cytoplasm hyperchromatic nuclei with moderate pleomorphism in a stroma showing inflammatory with infiltrate. adjacent ducts show ductal carcinoma in situ comedo type.,right breast lump biopsy:invasive carcinoma nst grade ii.modified bloom richardson score is 7 9.tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MR1905830,left breast mass carcinoma breast.,left breast biopsy.,received 4 grey white linear cores measures 0.8 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma with infiltrating neoplasm arranged in sheets nests and areas of necrosis. the cells are round to oval hyperchromatic nuclei. scant cytoplasm.mitosis 3 4 10hpf . areas of necrosis seen.,left breast biopsy.invasive carcinoma nst grade 2.modified bloom richardson score is 7 9(3+2+2).
MR1905891,right breast lump carcinoma breast.,biopsy from right breast.,received 2 grey white linear cores measures 0.2 to 0.5cm. entire tissue processed.,section shows multiple cores of breast tissue with hyalinised stroma and few scattered ducts with periductal inflammatory infiltrate.,biopsy from right breast:benign breast tissue.suggest repeat biopsy from representative area if clinically warranted.
MR1906142,left breast mass carcinoma breast.,biopsy from left breast.,received grey white multiple linear cores measures 0.5 to 1cm. entire tissue processed.,section studied shows linear cores of fibrofatty tissue infiltrating lesional cells arranged in sheets and nests. the cells are round to oval with pleomorphic nucleus showing hyperchromasia and moderate amount of eosinophilic cytoplasm. stroma shows desmoplasia and inflammatory infiltrate. foci of solid ductal carcinoma in situ seen.,biopsy from left breast:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MR1908324,right breast lump lumpectomy.,a) right breast lumpectomyb) right sentinel lymph node dissectionc) right axillary dissection.,a) received single fibrofatty tissue measures 8x5x4cmcut surface show firm ill defined firm lesion measures 2x2x1.8cm.distance from margins :medial margin : 1.2cmlateral margin :1.4cmsuperior margin :1.5cminferior margin :1cmdeep margin : 0.8cmb) received 3 lymph nodes largest measures 2.5x2x1cm.c) received fibrofatty tissue measures 7x6x5cm.largest lymph node measures 2.2x1.5x1.3cm cut surface infiltration seen.,section from the lesion show breast tissue harboring an invasive neoplasm composed of pools of mucin with floating tumor cells in nests and tubules. the cells show mild pleomorphism and hyperchromasia.,a) right breast lumpectomy:mucinous carcinoma.modified bloom richardson score is 2+2+1 5 9 grade 1.tumor measures 2cm in greatest dimension.ductal carcinoma in situ not identified.all resected margins are free of tumor.b) right sentinel lymph node dissection:1 out of 3 nodes show metastasis measures 0.4cm.no extranodal extension.c) right axillary dissection:10 lymph nodes examined are free of tumor (0 10).total 1 out of 13 nodes show metastasis 1 13).
MRA101148,right breast lump.,biopsy from right breast lump.,received 4 grey brown to grey white linear core measures 0.3 to 1cm. entire tissue processed.,section shows multiple cores of fibroadipose tissue harboring an invasive neoplasm in diffuse sheets and nests .the cells show marked pleomorphism with hyperchromatic nuclei and prominent nucleoli. extensive inflammatory infiltrate and areas of hemorrhage noted.,right breast biopsy :invasive carcinoma nst grade iii.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MRA101489,post right mastectomy right chest wall mass.,right chest well mass.,receive 4 grey white to grey brown linear cores measuring 1.2 to 1.4cm.entire tissue processed.,section from the linear cores of tissue shows a neoplastic lesion arranged in nests cords and tubules. cells are pleomorphic with high nuclei cytoplasmic ratio and hyperchromatic nuclei. atypical mitotic figures are discerned. focal clearing of cytoplasm noted.,right chest well mass biopsy( post right mastectomy) :suggestive of recurrent carcinoma in a known and treated case of carcinoma breast.
MRA102335,carcinoma breast.,biopsy from liver.,received 3 grey white to grey yellow linear cores measuring 0.8 to 1cm. entire tissue processed.,the section shows linear cores of liver parenchyma exhibiting areas of sclerosis and infiltration by tumor arranged in nests and cords. the tumor cells are round to cuboidal with enlarged ovoid hyperchromatic nuclei and moderate amount of cytoplasm. adjacent liver parenchyma shows mild portal inflammation.,biopsy from liver:metastasis in a known case of carcinoma breast..
MRA102876,papilloma left breast,wide excision of papilloma,received fibrofatty tissue measures 3.3x2.5x1.5cm.on serial sectioning a grey white granular areanoted measures 1.3x1.2x1.2cm. located at the following distances from respective margins: superior margin 1cminferior margin 0.9cmmedial margin 1.5cmlateral margin 0.2cmdeep margin 0.1cm,multiple section shows multiple dilated ducts and consists of papillary projection with fibrovascular core lined with cuboidal ductal epithelial cells. the ducts are lined with outer myoepithelial cells. there is no evidence of atypia of cells or invasion carcinoma.the resected margins superior margin fibrofatty tissue no ducts are seen margins are free of tumor.inferior margin fibrofatty tissue no ductal epithelium are seen margins are free of tumor.medial margin one duct is seen with ductal papilloma margins are free of tumor.deep margin free from the tumor inked margin is free.,wide excision with intraductal papillomatousno evidence of invasive carcinoma
MRA105574,known case of right breast.,biopsy from right chest wall lesion (posterior),received 4 grey white linear cores measures 0.5 1.5cm. entire tissue processed.,linear cores of fibrous tissue infiltrated by a neoplasm arranged as cords tubules and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is hyalinised,biopsy from right chest wall lesion (posterior):invasive carcinoma favor metastatic carcinoma of ductal origin in a known case of carcinoma right breast.
MRA105943,known case of carcinoma left breast ( post op ).,biopsy from right breast lump.,received multiple linear cores measure s0.3 to 0.6cm. entire tissue processed.,section show linear cores of fibrocollagenous tissue with occasional ducts lined by epithelial cells having bland nuclear feartures surroundings lymphocytes are seen.,no evidence of malignancy in the section studied.
MRA108604,now left breast lesion carcinoma breast.,biopsy from left breast.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section show linear cores of tumor composed of round to oval cells arranged in diffuse sheets and nests. these cells show high n:c ratio pleomorphic nucleus and scant to moderate cytoplasm. mitosis are discerned.,left breast lesion biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is (3+2+2) 7 9
MRA108969,case of right chest wall recurrence in an operated case of right breast carcinoma.,a) right chest wall lesion wide excision.b) revised medial margins.,a) received wide excision specimen measures 5.5x4x1.5cm. skin ellipse measures 5.5x2.9cm. skin surface shows puckering on cut surface single grey white from lesion seen measures 1.9x1.8x1.5cm. distance from margins :superior : 1 cm.inferior : 1.5 cm.medial : 0.5 cm.lateral : 0.6 cm.deep : 1 cm.skin : 0.2 cm.representative sections are submitted.b) received medial margin : single grey brown soft tissue measures 1.5 x 1 x 0.5 cm. entire tissue processed.,section shows tumor cells in diffuse sheets nets and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,a) right chest wall lesion wide excision :suggestive of recurrent invasive carcinoma in a known and treated case of carcinoma breast. tumor measures 1.9 cm in greatest dimension. tumor is reacting upto the dermis of the overlying skin without ulceration. all margins of resection are free of tumor.b) revised medial margins :negative for malignancy.
MRA108990,solid cystic lesion in left breast.,biopsy from left breast lesion.,received 4 grey white to grey brown linear cores measuring 1 to 1.3cm.entire tissue processed.,linear cores of tissue demonstrate proliferation of spindle and stelate cells in a myxoid stroma. there are prominent areas of fibrocollagenous stroma. one of the cores exhibit scattered islands of squamous epithelium with notable keratization.,biopsy from left breast lesion : phyllodes tumor. metaplastic carcinoma.needs further confirmation on excised tissue.
MRA109903,lump right breast.,wide local excision lumpectomy right breast,received skin covered fibrofatty tissue measuring 7x6x5cm. skin ellipse measures 6x0.5cm. tumor measures 2x2x2cm. cut surface grey white.distance from margins :superior : 1cm.inferior : 2cm.medial : 3cm.lateral : 1.5cm.deep : 2.5cm.,tumor :multiple section from the tumor shows clumps and groups of pleomorphic polyhedral cells with hyperchromatic nucleus and eosinophilic cytoplasm.modified br score is 7 9 nuclear grade ii.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9 nuclear grade ii.lymphovascular invasion indeterminate.perineural invasion present.ductal carcinoma in situ not present.resected margins are :superior free of tumor.inferior free of tumor.medial free of tumor.lateral free of tumor.deep free of tumor.,wide local excision right breast :invasive ductal carcinoma nuclear grade ii.lymphovascular invasion not present.perineural invasion present.ductal carcinoma in situ not present.all resected margins are free of tumor.
MRA110056,carcinoma left breast post op.,biopsy from chest wall.,received multiple grey white linear cores measures 0.5 to 1.4cm. entire tissue processed.,section shows linear cores of fibrous tissue harboring an infiltrating lesion arranged in tubules and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma shows desmoplasia with areas of hemorrhage and necrosis.,biopsy from chest wall:the features are suggestive of metastatic deposits from breast in a known and treated case .
MRA110728,case of carcinoma breast.,a) biopsy from endometrium.b) biopsy from cervix.,a) received multiple grey white to grey brown soft tissue bits altogether measuring 1x0.5x0.2 cm.entire tissue processed.b) received two grey white to grey brown soft tissue bits altogether measuring 0.5x0.5x0.2 cm.entire tissue processed.,a) section show fragment of endocervical glands lined by cells having bland nuclear features and mucin vacuoles. stroma show is cellular with plump spindle stromal cells. areas of eosinophilic secretion and hemorrhage noted.b) section show endocervical gland and cellular stroma with plump spindle stromal cells. congested blood vessels. no atypical cells seen.,a) endometrial biopsy:shows endocervical glands.negative for malignancy.b) cervix biopsy:shows chronic endocervicitis.negative for malignancy.
MRA110794,post mrm status of left breast for carcinoma left breast.heterogenous nodule in right breast(12 o clock).,biopsy from right breast nodule.,received multiple grey white to grey brown linear cores measures 1 to 1.2cm.entire tissue is processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged as tubules cords and sheets of pleomorphic cells with hyperchromatic round to oval nuclei and moderate cytoplasm.,biopsy from right breast lesion.invasive ductal carcinoma grade 2.mbr score is 7 9.tubule formation 2nuclear pleomorphism 3mitotic figures(6 7 10hpf) 2 7 9
MRA111305,carcinoma breast.,biopsy from left lung lesion.,received multiple grey white to grey brown linear cores 0.5 to 1.2cm. entire tissue processed.,linear cores of tissue demonstrating a cellular lesion arranged in sheets of round to oval neoplastic cells with ovoid dark nucleus with irregular contours exhibiting marked nuclear pleomorphic and pale eosinophilic cytoplasm. there are areas of necrosis bizarre giant cells and hyperchromatic pleomorphic cells with atypical mitotic figures and interspersed vascular channels. focal areas of necrosis seen.,biopsy from left lung lesion:high grade malignancy metastases in a known case of carcinoma breast.suggest ihc.
MRA111817,liver lesion possibility of metastasis.,liver lesion core biopsy (post op left breast carcinoma).,received 5 grey brown linear cores measures 1.2x1.5cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in nests and sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,liver lesion core biopsy (post op left breast carcinoma):suggestive of metastatic carcinoma most possible breast.
MRA112162,known case of carcinoma breast.,biopsy from abdominal nodes.,received 5 linear cores of 0.8 to 1cm. entire tissue processed.,section shows multiple linear cores of tissue harboring a neoplastic lesion arranged in sheets in focal areas it is arranged in tubules and nests. the cells are markedly pleomorphic with hyperchromatic nuclei few demonstrating prominent nucleoli and moderate cytoplasm. mitosis seen. intervening areas show lymphocytic infiltrates. areas of hyalinisation and necrosis seen.,biopsy from abdominal nodes:metastatic deposits probably from breast.
MRA113080,known case of carcinoma right breast.,biopsy from left axillary lymph node.,received 6 grey white linear cores measures 0.8 1.5cm. entire tissue processed.,section shows linear cores of lymph node parenchyma with tumor infiltrating in the form of nests sheets and trabecular composed of polygonal cells with high n c ratio hyperchromatic pleomorphic nucleus and moderate eosinophilic cytoplasm intervening stroma is desmoplastic.,biopsy from left axillary lymph node:metastatic deposits in a known case of carcinoma breast.
MRA113529,right axillary node deposit.,right axillary node biopsy.,received eight grey white to grey brown linear cores measures 0.8 to 1.5cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right axillary node biopsy :positive for malignancy.suggest of metastatic carcinoma in known case of carcinoma breast.
MRA113804,known case of carcinoma breast,a) amp b) d5 d6 extradural mass,a) received multiple grey white to grey brown soft tissue bits measures 2x1x1cm. b) received multiple greywhite to grey brown soft tissue bits altogether measures 1x0.5x0.5cm,multiple sections studied from the submitted specimen show fragments of fibroadipose tissue infiltrated by sheetsof large cell with vesicular chromatin prominent nucleoli and irregular nuclear borders. abundant nuclear debris noted. extensive crush artifacts noted,poorly differentiated malignancy known and treated case of carcinoma breast.report on ihc to follow
MRA114819,known case of carcinoma left breast.liver lesion.,liver lesion biopsy.,received multiple linear cores measures 0.4 to 1.4cm entire tissue processed.,sections show linear cores of liver parenchyma harboring a lesion arranged as sheets nests glandular pattern few cords and underlying dispersed cells. the individual cells show increased nucleo cytoplasmic ratio pleomorphic hyperchromatic nuclei with occasional prominent nucleoli. occasional mitotic figures are discerned. intervening stroma is fibrocollagenous and infiltrated by lymphocytes few plasma cells. the adjacent liver parenchyma is non cirrhotic.,liver lesion biopsy :features an suggestive of metastasis in a known case of carcinoma left breast.suggest ihc for gata3.
MRA115705,right breast carcinoma post mrm 2013.multiple liver lesion metastatic.,liver biopsy.,received multiple grey white linear cores measuring 0.8 to 1.2cm. entire tissue processed.,section shows linear cores of liver tissue harboring in infiltration lesion arranged in nests cords and vague tubules comprising of polygonal cells with round to oval hyperchromatic nuclei and moderate eosinophilic cytoplasm. brisk mitosis noted. adjacent areas shows hepatocytes arranged in trabeculae stroma shows extension hyalinisation and focal areas of necrosis.,liver biopsy :metastatic ductal carcinoma in a known and treated cases of carcinoma right breast.
MRA116011,left breast lump possibility of carcinoma breast.,biopsy from left breast lump,received 5 grey white to grey brown linear cores measures 0.8 to 1.2cm. entire tissue processed.,section shows multiple cores of fibroadipose tissue with an invasive neoplasm in sheets nests and cords the cells show moderate nuclear pleomorphism and increased mitosis.n,biopsy from left breast lump:suggestive of invasive carcinoma ductal type (nos)modified bloom richardson score is 7 9 grade ii.tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MRA117001,carcinoma breast.,biopsy form left lung.,received multiple grey white linear cores measures 0.8 to 1cm. entire tissue processed.,sections studied show fibrous tissue harboring an infiltrating lesion arranged in nests. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma is desmoplastic with areas of hemorrhage and necrosis.,biopsy form left lung:metastatic deposits in a known and treated case of carcinoma breast.
MRA118372,carcinoma breast with lung mets.,biopsy from lung lesion.,received 4 grey white linear cores measures 0.8 1cm. entire tissue processed,section studied reveal fragments of linear core biopsy bits of tumor arranged predominantly in sheets nest and occasional vague glandular pattern. lesional cells are round to oval hyperchromatic nuclei moderate eosinophilic cytoplasm. adjacent stroma show lymphoplasmacytic infiltrate.,biopsy from lung lesion:poorly differentiated malignancythe possibilities considered are 1. neuroendocrine neoplasm primary 2. metastatic deposits in a known case of carcinoma breast.suggest ihc.
MRA118386,right breast lump carcinoma breast.,right breast lump biopsy.,received 5 grey white to grey brown linear cores 0.5 to 1.2cm. entire tissue processed.,section show linear cores of breast tissue showing invasive sheets of dysplastic ductal cell showing moderate pleomorphism hyperchromatic nuclei. the intervening stroma show desmoplasia and mild mononuclear infiltrate.,right breast lump biopsy :invasive carcinoma of ductal origin nst grade 1.modified bloom richardson score is 5 9tubule formation : 3nuclear pleomorphism : 1mitotic figures : 1 5 9
MRA118854,carcinoma right breast post mrm.left breast lump cystic with thick wall and solid component likely malignant.,biopsy of left breast lump.,received multiple grey white to grey brown linear fragments altogether measures 0.3 0.4cm.,section shows cores of breast tissue with an infiltrating neoplasm predominantly in sheets. the cells have moderate hyperchromatic nucleoli. one of the cores show sheets of spindle cells showing moderate atypia and increased mitosis with atypical mitotic figures.mbr score 7 9grade iitubule formation 3nuclear pleomorphism 2mitotic figures 3 8 9,features are suggestive of recurrence possibilities considered area) invasive ductal carcinoma (poorly differentiated)b) metaplastic carcinomasuggest ihc.
MRA119143,left breast lump carcinoma breast.,left breast lump.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue infiltrate by neoplastic cells arranged in sheets. the cells have round to irregular hyperchromatic nuclei inconspicuous nucleoli and moderate cytoplasm. bizarre nuclear forms are noted. areas of necrosis is noted.,left breast lump biopsy :suggestive of high grade malignant spindle cell neoplasm. metaplastic carcinoma. malignant phyllodes tumor. needs further confirmation on larger specimen.
MRA119875,liver lesion metastasis.,biopsy from liver lesion.,received grey white linear cores measures 0.8 to 1cm. entire tissue processed.,cores of tumor tissue composed of linear cords and nests of cells with increased n:c ratio moderate cytoplasm and pleomorphic hyperchromatic nuclei in a desmoplastic stroma. one of the fragments show liver parenchyma.,biopsy from liver lesion :metastatic carcinoma probably from breast.
MRA119878,known case of carcinoma breast s p surgery and ct.now f18 bone scan suggestive of multiple skeletal metastases.,biopsy from right iliac bone lesion.,received soft 8 bony tissue fragments altogether measuring1x1x0.5cm. entire tissue is processed.,fragments of bony trabeculae with intervening marrow harboring neoplasm arranged in acinar pattern and as cords. the neoplastic cells have hyperchromatic nuclei and moderate cytoplasm. also noted is hemorrhage.,metastatic carcinoma biopsy from right iliac bone in a known case of carcinoma breast.
MRA120269,carcinoma breast relapse.,lung lesion biopsy.,received 8 greywhite to greybrown linear core measuring 1 to 1.2cm. entire tissue processed.,section shows linear cores of lung parenchyma harboring a lesion arranged in acinar and cribriform pattern. the cells are columnar having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmopla with sheets of neoplastic cells having moderate amount of cytoplasm vesicular nucleus and prominent nucleoli. areas of hemorrhage and necrosis seen.,lung lesion biopsy:glandular malignancy metastatic from breast.suggest ihc.
MRA120555,right breast lump carcinoma breast.,biopsy from right breast,received 4 grey white to grey brown linear cores measures 1.5 2cm entire tissue processed,section shows linear cores harboring an infiltrating neoplasm increased in trabecular and cords of cells exhibiting increased n c ratio hyperchromatic pleomorphic nuclei moderate amount of pale eosinophilic cytoplasm. the intervening stroma shows presence of fibrocollagenous connective tissue.,biopsy from right breast:invasive carcinoma breast no special type grade iimodified bloom richardson score is 7 9( 3+2+2)
MRA120653,left breast lump carcinoma breast,biopsy from left breast.,received multiple grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue harboring a lesion arranged in islands with loosely scattered atypical cells with dark irregular nuclei some with prominent nucleoli and moderate to abundant pale eosinophilic cytoplasm. scattered tumor giant cells are noted . mitotic figures are rare. stroma shows extensive hyalinisation and fibrosis.,biopsy from left breast.invasive carcinoma nst grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MRA121179,carcinoma right breast post opnow mediastinal lesion with chest wall invasion with nodes,biopsy from anterior mediastinal lesion,received multiple grey white to grey brown linear cores measures 1 to 1.3cm. entire tissue is processed.,linear cores of tissue exhibiting a neoplastic lesion arranged in nests and islands consisting of round to oval neoplastic cells demonstrating moderate to marked nuclear pleomorphism brisk mitotic activity amidst prominent areas of necrosis and fibrosis.,biopsy from anterior mediastinal lesion:poorly differentiated carcinoma metastatic in a known case of carcinoma breastneeds ihc.
MRA121783,carcinoma right breast post op. right chest wall lesion metastasis,biopsy from right chest wall lesion.,received 4 grey white to grey brown soft linear cores measuring 1 to 1.2 cm.entire tissue processed.,linear cores of tissue infiltrated by cords and sheets of round to oval neoplastic cells demonstrating moderate nuclear pleomorphism and eosinophilic cytoplasm amidst a dismoplastic stroma. atypical mitotic figures are discerned.,biopsy from right chest wall lesion:metastatic carcinomatous deposits in known case of carcinoma breast.
MRA121882,carcinoma breast post mrm with chest wall recurrence.,chest wall swelling excision biopsy(post mrm carcinoma right breast).,received skin covered fibrofatty tissue measuring 2 x 1.8 x 1 cm salivary gland measuring 1.3 x 0.6 cm cut surface show a greywhite lesion measuring 1.2 x 1 x 0.5 cm.distance from margins:medial margin 0.3cm.lateral margin 0.3cm.deep margin 0.1cm.representative sections submitted.,section shows tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,chest wall swelling excision biopsy(post mrm carcinoma right breast) :suggestive of recurrent invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+2+3). margins of resection are free of tumor.
MRA122989,left hilar lung masstreated case of carcinoma breastcarcinoma lung mets from carcinoma breast.,biopsy from left lung mass.,received multiple grey white to grey brown soft tissue bits measures 0.4 to 0.6cm. entire tissue is processed.,linear cores of lung parenchyma demonstrating small islands of round to cuboidal cells with centrally placed nuclei and moderate amount of pale staining cytoplasm floating in pools of mucin.,biopsy from left lung mass:invasive mucinous carcinoma metastatic primary please correlate with histopathologic details of breast lesion.
MRA123033,history of carcinoma breast post mrm.complaints of post menopausal bleeding.,biopsy from cervical polyp.,received 3 grey brown tissue masses.largest polypoidal mass.other two fragments altogether measuring 2x1.5x1 cm.case of grey brown.,section shows unencapsulated neoplasm composed of occasional irregularly shaped benign endocervical type glands admixed with smooth muscle component composed of variably sized and shaped fascicles embedded in collagenous background.,adenomyoma cervix polyp.
MRA123103,right breast.,right breast biopsy.,received 10 linear core grey white linear core measures 1 to 1.5cm. entire tissue processed.,section studied shows fibrous tissue harboring an infiltrating lesion arranged in nests and islands. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. occasional mitotic figures are discerned. stroma is desmoplastic with mild lymphomononuclear cells infiltrates and areas of hemorrhage and calcification.,right breast biopsy :invasive carcinoma nst grade 2.modified br score is 7 9tubule formation : 3nuclear pleomorhism : 2mitotic figures : 3 ......... 7 9 .........ductal carcinoma in situ solid pattern is seen.
MRA123180,carcinoma breast post op.,biopsy from endometrial lesion.,received single grey brown fibrofatty measures 3.5x1.5x0.5cm. entire tissue processed.,the section shows a polygonal lesion showing surface cellular lining epithelium. the stroma shows endometrial glands with many showing marked cystic dilatation. intervening stroma is fibrotic and congested. thick walled vessels are seen.no atypia is discerned,biopsy from endometrial lesion:simple endometrial polyp.no evidence of malignancy in the section studied.
MRA123324,biopsy from liver lesion.,liver lesion biopsy.,received multiple grey brown linear cores measures 0.8cm. enter tissue processed.,sections shows linear cores of hepatic parenchyma harboring an infiltrative neoplasm arranged in nests. the neoplastic cells shows increased n:c ratio pleomorphic hyperchromatic nucleiand moderate amount of pale eosinophilic cytoplasm,liver lesion biopsy :possible for malignancy.favour metastasis in a known case of carcinoma breast. suggest ihc
MRA124979,left nipple discharge in a known case of carcinoma right breast (post mrm).,left breast left cone excision with part of inverted nipple.,received single fibrofatty measuring 6 x 4.5 x 1.8 cm. on serial sectioning dilated duct is seen measuring 0.2 cm in diameter. also seen in continuation with the duct ill defined on greywhite area measuring 3 x 2.8 x 1.5 cm. specimen is serially sliced and submitted entirely.,section show breast parenchyma showing hyperplastic ductules with papillary pattern with fibrovascular core. individual cells having round to oval vesicular nuclei prominent nucleoli and moderate amount of cytoplasm. stroma is fibrous with stromal cells and congested blood vessels.,left breast left cone excision with part of inverted nipple :ductal carcinoma in situ of solid and cribriform pattern with intermediate nuclear grade. estimated size of dcis is 2.8 cm in greatest dimension. adjacent breast tissue shows intraductal papilloma. nipple is free of tumour. margins of resection are free of tumor.
MRA125121,known case of carcinoma left breast with brain metastasis post op status.,biopsy from left anterior axillary lesion.,received 6 grey white linear cores measuring 0.8 1 cm.entire tissue processed.,section shows cores of myxoid tissue with a few rbcs interspersed.,no viable tumor seen.further work up cannot be attempted on this tissue.suggest repeat biopsy if clinically deemed necessary
MRA125269,left breast lesion birads iv.,biopsy from left breast lesion.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in cords and abortive tubules. the cells have round hyperchromatic nuclei and moderate cytoplasm. surrounding stroma is desmoplastic nuclei and moderate cytoplasm. surrounding stroma is desmoplastic.,left breast lesion :invasive ductal carcinoma grade ii.modified bloom richardson score is (3+2+2) 7 9
MRA126260,left breast lesion birads iv.,biopsy from left breast.,received 4 grey white linear core measuring 1 to 1.1cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters cords and trabeculae. these cells have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma shows lymphocytic infiltrate.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MRA126622,right breast mass carcinoma breast.,right breast biopsy.,received 4 grey white to grey brown linear core measuring 0.7 to 0.8cm. entire tissue processed.,section shows cores of breast parenchyma showing few dilated glands lined by two to tissue layer of cells having avoid hyperchromatic nuclei and scanty cytoplasm. stroma shows extensive desmoplasia and scattered atypical cells having hyperchromatic nuclei seen..,right breast biopsy :atypical cells seen against a dense desmoplastic stroma.highly suspicious of malignancy.suggest repeat biopsy.
MRA126824,right lung nodule metastatic.,biopsy from right lung nodule.,received multiple grey white linear cores measures 0.5 to 1cm. entire tissue processed.,sections studied show linear cores of lung parenchyma with an infiltrating lesion arranged in nests and islands. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned. stroma is desmoplastic with scattered lymphomononuclear cell infiltrates.,biopsy from right lung nodule :the features are suggestive of metastatic poorly differentiated carcinomatous deposit in a known case of carcinoma breast. suggest ihc.
MRA129531,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows cores of breast parenchyma shows lesion arranged in fascicles and bundles. the cells are spindly to oval have pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. brisk mitotic activity is noted. few compressed ducts and seen. stroma is scanty.,biopsy from left breast lump. suggestive of phylloides tumor border line malignantneeds further conformation on larger excision specimen.
MRA129651,know case of carcinoma breast post op now multiple nodes supraclavicular axillary.,biopsy from supraclavicular node.,received five grey white linear cores measures 0.3 to 0.5 cm. entire tissue processed.,section studied shows cores of fibrous tissue harbors infiltrative lesion arranged in sheets and nests. the cells are oval have pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderate amount of eosinophilic cytoplasm. stroma shows desmoplasia.,supraclavicular node biopsy :suggestive of metastatic tumor deposits of carcinoma in known case of carcinoma breast.
MRA130479,follow up case of left carcinoma breast post mrm (2 years ago). post adjuvant chemotherapy and chest wall rt.,skin ellipse biopsy from left chest wall and axilla (in a known case of carcinoma breast post op ct rt).,received 2 skin covered soft tissue bits measuring 1.5x1x0.8cm. entire tissue processed.,section from both skin ellipse shows stratified squamous epithelium. no loss of polarity is seen. stroma shows fibrocollagenous tissue with few lymphocytes. no atypia is seen.,skin ellipse biopsy from left chest wall and axilla (in a known case of carcinoma breast post op ct rt) :features are suggestive of chronic non specific inflammation.negative for malignancy.
MRA130500,known case of carcinoma breast post mrm,biopsy from right pubic bone.,received blood clot measures 0.5x0.5x0.3cm. entire tissue processed no bony bits identified,sections shows multiple hemorrhagic cores and few bony bits with a lesion arranged in sheets nests and acinar pattern. cells have round to oval hyperchromatic nuclei and moderate eosinophilic cytoplasm. frequent mitosis noted.,biopsy from right pubic bone:metastatic carcinoma in a known case of carcinoma breast.suggest ihc for gata3
MRA131263,known case of carcinoma right breast.,biopsy from right breast.,received multiple grey white to grey brown linear cores measures 0.3 to 1 cm. entire tissueis processed.,section showing infiltrative lesion arranged in glands sheets and nests. the cells are round to oval hyperchromatic nuclei with moderate to abundant cytoplasm. inflammatory infiltrate composed of lymphocytes and neutrophils. hemosiderin laden pigments are seen around the nucleus.,right breast biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
MRA132318,case of right breast lump under evaluation.,right breast wide excision.,received skin covered soft tissue mass measures 9x6x6cm. skin ellipse measures 5x1.5cm. surface of the skin unremarkable. cut surface no obvious tumor seen. single grey white ill defined fibrotic area measures 1.5x1x1cm.distance from the margin:superior margin 1cm.inferior margin 1.2cm.medial margin 1.2cm.lateral margin 1.2cm.deep margin 1.3cm.,sections shows lesion composed of multiple dilated ducts of varying size with intervening fibrous stroma. the ducts are lined by inner hyperplastic epithelial layer arranged as papillae focally and outer intact myoepithelial layer. the epithelium is columnar and show stratification. there is moderate nuclear pleomorphism and occasional mitosis. cribriform type of ductal carcinoma in situ is also noted. one of the ducts is markedly dilated and show complex branching papillae. lumen shows secretions pigment laden macrophages and calcifications. all the margins are free of tumor.,right breast wide excision.papillary neoplasm.morphology favors papillary ductal carcinoma in situ with intraductal papilloma.suggest ihc to rule out or confirm invasive component.
MRA13263,mass in right breast carcinoma breast.,biopsy from right breast.,received 3 grey white linear cores measuring 1 to 1.5cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic .foci of calcification seen.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
MRA132873,complaint of right carcinoma breast with (diagnosis done old case) now presenting with recurrence.,right chest wall lesion wide local excision.,received skin covered fibrofatty tissue measuring 7.5x6x2.5cm.skin ellipse measuring 7x3.5cm shows an ulcerated greywhite lesion measuring 2.5x1x0.7cm.located at the following ditances from respective margin: superior margin 3cm.inferior margin 2.5cm.medial margin 2.3cm.lateral margin 2.2cm.deep margin 1.1cm.distance from skin margins:superior margin 2.5cm.inferior margin 1.8cm.medial margin 0.6cm.lateral margin 1cm.,sections reveal ulcerated skin with underlying neoplastic lesion arranged in glandular configuration and sheets consisting of cuboidal cells with vesicular nuclei moderate atypia and pale eosinophilic cytoplasm. mitotic figures are discerned. lymphovascular invasion and perineural invasion are discerned. all resected margins are free of tumor.,right chest wall lesion wide local excision:suggestive of metastatic carcinoma in a known case of carcinoma right breast.suggest ihc.lymphovascular invasion and perineural invasion are identified.all resected margins are free of tumor.
MRA134182,known case of left breast post modified radical mastectomy. right breast lump birads iv.,right breast lump core biopsy.,received four grey white to grey brown linear cores measures 0.8 to 1.2 cm. entire tissue processed.,section shows cores of tissue infiltrated by ductal carcinoma in situ. no definite evidence of invasion is seen.,right breast lump core biopsy (post op carcinoma left breast ) :shows features of ductal carcinoma in situ of solid cribriform and comedo pattern with intermediate nuclear grade. no definite evidence of invasion is seen.
MRA134525,carcinoma left breast post opright axillary node metastatic.,biopsy from right axillary node.,received multiple grey white to grey brown linear cores measuring 1.3 to 1.6cm.entire tissue is processed.,linear cores of lymphoid tissue infiltrated by a neoplasm arranged as islands and clusters.the neoplastic cells have vesicular nucleoli conspicuous nucleoli and abundant eosinophilic cytoplasm.,metastatic carcinoma biopsy right axillary lymph nodes in a known case of carcinoma left breast.suggest confirmation.
MRA134763,right axillary node,biopsy from axillary node,received multiple grey white fragments each measures 0.3 0.4cm.entire tissue is processed,sections from right axillary node show sheets of cells. the cells show round nucleus conspicuous nucleoli and scanty cytoplasm.native nodal tissue not seen,metastatic carcinoma in a known case of carcinoma left breast.
MRA135739,carcinoma breast post op.,biopsy from endometrial tissue.,received multiple grey brown to grey black mucinous soft tissue bits measures 1.5x1x0.5cm. entire tissue processed.,sections show tissue cores showing only fibrocollagenous conclusive tissue. no evidence of malignancy.,endometrial biopsy :shows only fibrocollagenous tissue. no viable cells are seen.kindly repeat biopsy if clinically indicated.
MRA135757,known case of carcinoma left breast.left breast lump recurrence.,core biopsy left breast.,received grey white to grey brown linear cores measuring 1 to 1.2cm.entire tissue is processed.,section shows cores of fibrofatty tissue harboring a neoplastic lesion arranged in diffuse sheets and cords.cells are pleomorphic with hyperchromatic nuclei and moderate eosinophilic cytoplasm.mitotic figures are discerned.,core biopsy left breast : invasive carcinoma recurrence.
MRA135918,carcinoma right breast.,a) right mastectomy with right axillary level i and ii lymph nodes.b) level iii lymph nodes.,a) received in : formalin.procedure : mastectomy with right axillary lymph nodes level i ii.laterality : right. total dimensions : medial to lateral 18cm. superficial to deep 4cm. superior to inferior 16cm.skin ellipse : 15.5x8cm. nipple : normal.scar surgical defect : not seen.tumor : single.tumour size : 4.3x3.3x3.2cm. location of tumor : retro areolar. deep margin : 0.3cm.muscle : present measures 3cmx2.5cm.adjacent breast : fibrofatty. axillary tail : 9x5.5x3cm.total number of nodes : 15 (specify if sentinel nodes sent )size of largest node : 3x2x2cm cut surface : greywhite matted.b) received fibrofatty tissue measuring 2x0.7x0.5cm.,a) multiple sections from breast parenchyma show a neoplastic lesion arranged in lobules nests cords and in diffuse sheets separated by fibrous septae.tumor cells show irregular vesicular nuclei dispersed chromatin moderate eosinophilic to clear cytoplasm.mitotic figures discerned.peritumoral lymphocytic infiltration seen.lymphovascular invasion and perineural invasion identified.ductal carcinoma in situ is not seen.,right breast right modified radical mastectomy: invasive poorly differentiated carcinoma probably of ductal origin.grade iii.modified br score is 8 9.tubule formation: 3nuclear pleomorphism: 3mitotic figures: 2tumor measures 4.3 cm in greatest dimension and is located in the retroareolar region quadrant. ductal carcinoma in situ is not seen.lymphovascular invasion is identified.perineural invasion is identified.posterior resection margin is 0.3cm away and free of tumor.nipple and areola is dermal infiltrates present epidermis is free of tumor.lymph nodes: 16 lymph nodes metastasis: 16 (16 16).largest tumor deposit measures 1.8cm.perinodal spread seen.summary: right mrm invasive poorly differentiated carcinoma probably of ductal origin.grade iii.nodal metastases present (16 16).perinodal spread seen.
MRA13605,multiple liver lesion metastasis.,biopsy from liver lesion.,received 6 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of liver parenchyma harboring invasive neoplasm arranged in nests and sheets occasional glandular pattern. the lesional cells are polygonal with abundant vacuolated to pale eosinophilic cytoplasm round hyperchromatic nucleus. some cells show intranuclear inclusion. stroma is desmoplastic.,liver biopsy :positive for malignancy.suggestive of metastatic deposits in known case of carcinoma breast.
MRA136235,known case of carcinoma right breast.post right mrm.,biopsy from right breast.,received multiple grey white to grey brown linear cores measuring 0.6 to 0.1cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters and tubules. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is fibrous.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2.tubuleformation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MRA136578,known case of carcinoma breast post op post chemotherapymultiple liver lesions,biopsy from liver lesion,received multiple grey white linear cores measures 1.5 to 1.8cm.entire tissue is processed,section studied shows linear cores of liver parenchyma showing highly cellular infiltrative lesionarranged in cords nests and tubules. the cells are oval with hyperchromatic nuclei moderate to abundant amount of cytoplasm and exhibit moderate nuclear pleomorphism. foci of myxoid stroma seen,biopsy from liver lesion:metastatic carcinoma from breast in a treated casesuggest ihc
MRA136762,case of carcinoma right breast status post mrm.,biopsy from sternal lesion.,received multiple grey white linear core measuring 0.5 to 1cm. entire tissue is processed.,fragmented linear cores of tissue exhibiting dyscohesive clusters and sheets of round to oval neoplastic cells demonstrating moderate to marked nuclear pleomorphism and eosinophilic cytoplasm with notable mitotic activity. large bizzare and multinucleated cells are also noted. intervening areas show fibrocollegenous stroma.,biopsy from sternal lesion :suggestive of the features are deposits of poorly differentiated carcinoma in a known case of carcinoma breast.suggest ihc for gata3.
MRA137083,post bcs right breast.,biopsy from right retroareolar region,received five grey white to grey brown linear cores measuring 0.7 to 1.0cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as tubules and cords. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma is elastotic.,invasive ductal carcinoma biopsy from right breast.modified br score 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MRA137681,known case of carcinoma left breast post treatment.now with right gingivo buccal sulcus lesion.,biopsy from right gingivo buccal sulcus ulcer.,received grey brown soft tissue bit measures 0.3x0.2x0.1cm. entire tissue processed.,section studied show dysplastic squamous epithelium with underlying subepithelium harboring neoplasm arranged in nest and cords which is composed of cell having round to oval vesicular nuclei with prominent nucleoli moderate amount of eosinophilic to clear cytoplasm. intracellular keratinization also seen. adjacent stroma show lymphoplasmacytic infiltrate.,biopsy from right gingivo buccal sulcus ulcer:moderately differentiated squamous cell carcinoma.
MRA138128,right chest wall lesion deposits.,biopsy from right chest wall lesion.,received multiple linear cores measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrous tissue with an infiltrating lesion arranged in nests and tubules. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus. stroma is desmoplastic with lymphocytes histiocytes and regenerating muscle bundles.,right chest wall lesion biopsy :recurrent poorly differentiated carcinoma in a known case of carcinoma right breast.
MRA138247,case of carcinoma breast multiple liver lesion liver metastasis.,biopsy from liver.,received 5 grey white linear cores measuring 1 to 1.2 cm.entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,liver core biopsy:positive for malignancy.suggestive of metastatic carcinoma most possible for breast.suggest ihc for further confirmation.
MRA138691,case of right mrm in 2014.now non healing.ulcer over the right mrm scar (medially).,biopsy from right chest wall.,received single skin covered soft tissue bits measuring 0.5x0.5x0.2 cm.entire tissue processed.,section show fragments of fibrocollagenous tissue with neoplastic lesion arranged in sheets. individual cells have pleomorphic round to oval hyperchromatic nuclei and moderate amount of cytoplasm. intermixed inflammatory cells. consisting of chiefly lymphocytes and few plasma cells noted.,biopsy from right chest wall :positive for malignancy.suggestive of recurrence of carcinoma in known and treated cease of carcinoma breast.
MRA138868,right axillary node deposits,biopsy from right axillary node.,received 4 grey white linear cores measures 1.5 2cm. entire tissue processed,sections shows multiple cores lymph nodes parenchyma harboring infiltrating lesion arranged in sheets and nests. the lesional cells are round to oval having hyperchromatic nuclei and moderate cytoplasm with admixed lymphocytes mitosis are seen.focal necrosis seen.,biopsy from right axillary node:metastatic carcinoma in a known case of carcinoma breastfocal necrosis seen.
MRA138940,carcinoma breast post op .now liver space occupying lesion metastatic.,biopsy from liver lesion.,received 4 grey white to grey brown linear cores measures 0.5 to 1 cm. entire tissue processed.,section shows linear cores of liver parenchyma harboring an infiltrative lesion arranged as diffuse sheets and tubules. the cells have round to oval hyperchromatic nucleus and scanty cytoplasm. mitotic figures discerned.,metastatic carcinoma biopsy from liver lesion in a known case of carcinoma breast.
MRA140239,known case of carcinoma breast.,biopsy from right lung nodule,received multiple linear cores measures 0.8 0.9cm.entire tissue processed.,section shows linear cores of lung parenchyma infiltrated by neoplastic cells arranged in lobular aggregates with areas of necrosis. the tumor cells have round hyperchromatic nucleus and moderate cytoplasm. mitosis is discerned.. adjacent stroma shows anthracotic pigment.,biopsy from right lung nodule:malignant lesionfeatures are suggestive of metastatic carcinoma in a known case of carcinoma breast.
MRA140264,carcinoma breast post opliver space occupying lesion metastases,biopsy from liver space occupying lesion,received multiple grey white to grey brown linear cores measures 0.5 to 0.6cm. entire tissue is processed,linear cores of liver tissue harboring a neoplasm arranged in trabecular pattern and in cluster. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is scant.,invasive carcinoma suggestive of metastasis in a known case of carcinoma breast biopsy of liver
MRA140485,right breast lesion carcinoma breast.,right breast lesion.,received 4 grey white to grey brown linear cores measures 0.8 to 1cm. entire tissue processed.,section studied show linear cores ares of breast parenchyma with aggregates of lymphoplasmacytic infiltrate and few tumor cells in glandular pattern and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lesion core biopsy(known case of carcinoma sigmoid colon) : positive for malignancy.shows tumor foci of adenocarcinoma. primary. metastasis. suggest ihc for further confirmation.
MRA140721,carcinoma breast post op multiple liver lesion.,biopsy from liver lesion.,received 5 grey white linear core measuring 1 to 1.5cm. entire tissue processed.,linear cores of tissue infiltrated by sheets nests tubules and cords of neoplastic cells demonstrating moderate nuclear pleomorphism and pale eosinophilic cytoplasm amidst a desmoplastic stroma.,biopsy from liver lesion:metastatic carcinoma in known case of carcinoma breast post surgery.
MRA140869,known case of carcinoma left breastright retroareolar mass,biopsy from right breast lump,received multiple grey white to grey brown linear cores measures 0.8 to 1.2cm. entire tissue is processed,section shows linear cores of breast parenchyma harboring a lesion arranged as cords. the cells have round to oval hyperchromatic pleomorphic nuclei and moderate to scanty cytoplasm. ductal carcinoma in situ solid type seen. stroma shows inflammatory infiltrate and areas of fibrosis,biopsy from right breast invasive carcinoma with lobular features nuclear grade 2ductal carcinoma in situ present
MRA140910,carcinoma right breast.,biopsy from right lung lesion.,received 5 grey white to grey brown linear cores measuring 0.6 to 1.0cm. entire tissue processed.,linear cores of lung parenchyma infiltrated by nests islands micro papillary configuration of neoplastic cells demonstrating moderate nuclear pleomorphism and eosinophilic cytoplasm. intervening fibrocollagenous stroma show mixed inflammatory infiltrate . there are areas of hemorrhage.,biopsy from right lung lesion:invasive carcinoma. primary secondarysuggest ihc.
MRA140973,known case of breast.right adnexal lesion possibility of carcinoma ovary.,biopsy from right adnexal lesion.,received multiple grey white to grey brown linear cores measures 0.6 1.2cm.,sections show linear tissue cores showing nests and sheets of neoplastic cells showing nuclearhyperchromasia moderate nuclear pleomorphism and valuable amount of pale eosinophiliccytoplasm. mitotic figures 4 5 hpf. the intervening fibrocollagenous connective tissue shows lymphoplasmacytic inflammation with focal myxoid appearance.,biopsy from right adnexal lesion:high grade carcinoma favor serous carcinoma ovarian.suggest ihc and clinical correlation.
MRA141745,lump right breast.,lumpectomy right breast.,received lumpectomy specimen measuring 9.5x6.5x3cm.cut surface shows multiple dilated ducts with adjacent fibrotic areas measuring 8x5.5x3cm.distance from the closest inked margin is 0.1cm.the ducts yielded cheesy grey brown material measuring 0.6x0.5x0.2cm.,multiple section shows dilated ducts lined with cuboidal epithelial cells lined with outer myoepithelial cells.surrounding ducts show epithelial hyperplasia microadenosis occasional ducts show atypical hyperplasia.there is no evidence of invasive ductal carcinoma.,lumpectomy breast with fibrocystic disease with epithelial hyperplasia.microglandular adenosis.
MRA141893,known case of carcinoma right breast,biopsy from right breast.,received single skin covered soft tissue bits measures 0.4x0.3x0.3cm. entire tissue processed.,section shows an infiltrative neoplasm with presence of overlying dermis. there is sheet like arrangement of neoplastic cells exhibiting abundant eosinophilic granular cytoplasm pleomorphic large vesicular nuclei with prominent nucleoli. surrounding stroma shows presence of fibrocollagenous connective tissue infiltrated by lymphoplasmacytic infiltrate.,biopsy from right breast:invasive carcinoma with apocrine differentiation.
MRA142037,left supraclavicular node metastasis.,biopsy from left supraclavicular node.,received 4 very tiny linear cores measures 0.3 to 0.5cm. entire tissue processed.,section studied shows linear cores of fibrocollagenous tissue harboring an invasive neoplasm arranged in glandular pattern trabeculae cords. the lesional cells are polygonal with moderate eosinophilic cytoplasm moderately pleomorphic hyperchromatic nucleus few cells showing prominent nucleoli and intranuclear inclusion. interspersed are lymphocytes plasma cells histiocytes thickened blood vessels.,biopsy from left supraclavicular node. :metastatic deposit of ductal origin in a known case of carcinoma left breast.
MRA142099,known case of carcinoma breast (2014).,biopsy from right clavicular mass,received 4 grey white linear cores measures 1 2cm. entire tissue processed.,section shows multiple cores fibrocollagenous tissue showing lesion in sheets. the cells are oval to spindle having hyperchromatic pleomorphic nuclei and moderate cytoplasm. tumor giant cells and multinucleated giant cells seen. foci of necrosis seen.,biopsy from right clavicular mass:poorly differentiated malignancy.please correlate clinically
MRA142249,multiple prelytic bone lesion metastasesknown case of carcinoma breast post op.,biopsy from left iliac lesion.,received single brown core measures 3cm.,section shows cells which are in sheets clusters and singly scattered . the cells are polygonal with plasmacytoid nuclei and moderate cytoplasm. areas of hemorrhage are seen.,left iliac lesion biopsy:1)metastatic deposits from breast primary2)plasma cell neoplasm.suggest further evaluation.
MRA142843,known case of right breast. multiple liver lesion metastasis.,biopsy from liver lesion.,received 5 grey white to grey brown linear cores each measures 1.5 to 2cm. entire tissue processed.,section show cores of liver parenchyma harboring an invasive neoplasm in nested and cord like architecture. the neoplastic cells have well defined cell borders moderate eosinophilic to clear cytoplasm pleomorphic change. adjacent liver parenchyma shows mild fatty change liver biopsy.,liver biopsy : metastatic carcinoma in a known case of carcinoma breast.
MRA142884,right infraclavicular mass deposit.,biopsy from infraclavicular mass.,received 5 grey white linear cores measures 1.2 1.5cm. entire tissue processed.,section shows linear cores of tissue infiltrated by cords islands and nests of neoplastic cells having round to oval pleomorphic hyperchromatic nuclei and moderate cytoplasm. few cells show clear to pale granular cytoplasm. mitotic figures 8 9 10hpf. stroma shows lymphoplasmacytic infiltrates. areas of necrosis seen.,biopsy from infraclavicular mass:suggestive of metastatic carcinoma.please look for primary in breast lung and git.
MRA142951,carcinoma right breast post mrm,lateral end of lesion breast biopsy.,received multiple grey white to grey brown linear cores 0.3 0.5cm. entire tissue processed.,section shows fragments of fibromuscular tissue with congested vessels hyalinised stroma and areas of hemorrhage noted.,lateral end of scar lesion breast biopsy:no evidence of malignancy in the material submitted.
MRA143046,known case of carcinoma left breast post op.,biopsy from left breast lesion.,received 4 grey white linear cores measuring 0.2 to 0.8cm. entire tissue processed.,section shows multiple linear cores with few glands and fibrocollagenous tissue along with focal areas of hyalinisation. few fibroblasts are noted. no atypical cells are seen.,biopsy from left breast lesion:no evidence of malignancy in the section studied.
MRA143269,carcinoma left breast.,biopsy from liver lesion.,received 5 grey white to grey brown linear cores measures 0.7 to 1.2cm. entire tissue processed.,section shows linear cores of hepatic parenchyma infiltrated by a lesion arranged as tubules and cords. the cells have round to oval hyperchromatic nucleus with moderate cytoplasm. stroma shows desmoplasia and focal myxoid change.,biopsy from liver lesion:metastatic adenocarcinoma in known case of carcinoma left breast.
MRA143592,right breast carcinoma post mrm and follow up.multiple bone lesion metastasis.,biopsy from iliac bone.,received 2 grey white linear cores measures 0.3 to 0.6cm. entire tissue processed.,section shows fragments of bone and fibrocollagenous tissue with an invasive neoplasm in sheets nests and vague glandular appearance with clear (moderate) cytoplasm round to oval nuclei with moderate pleomorphic and hyperchromatism. there are areas of hemorrhage and necrosis.,biopsy from iliac bone.suggestive of metastatic carcinoma in a known case of carcinoma breast.
MRA143643,known carcinoma left breast post mrm.,biopsy from right breast.,received multiple grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section from breast parenchyma shows neoplastic lesion arranged in cords trabecular and in sheets. the cells have abundant cytoplasm with hyperchromatic nuclei few of the cells show intranuclear inclusions. areas of hyalinisation seen. mitosis seen.,biopsy from right breast invasive carcinoma nst grade 2modified bloom richardson score is 7 9tubule formation 3nuclear pleomorphism 3mitotic figures 1 7 9
MRA144113,known case of carcinoma left breast,left chest wall lesion.,received multiple grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,section shows 3 linear cores showing nests trabeculae cords and dispersed individual tumor cells showing increased nucleo cytoplasmic ratio pleomorphism hyperchromasia and variable amount of pale clear to eosinophilic cytoplasm . numerous signet ring cells seen. abundant fibrocollagenous stroma ( suggestive of desmoplastic response) seen. there are few congested blood vessels and lymphoplasmacytic inflammatory infiltrate.,left chest wall lesion:metastatic adenocarcinoma.suggestive ihc and clinical correlation to ascertain site of primary.
MRA144596,follow up case of carcinoma right breast.,biopsy from right middle lobe,received 6 grey white to grey brown linear cores measuring 0.5 to 1cm. entire tissue processed.,linear cores of lung parenchyma infiltrated by nests and islands of round to oval neoplastic cells exhibiting moderate to marked nuclear pleomorphism and eosinophilic cytoplasm with notable mitotic activity. intervening areas show fibrocollagenous and fibrovascular tumor.,biopsy from right middle lobe:positive for malignancy.favor metastatic carcinoma from breast.suggest ihc.
MRA144694,carcinoma left breast post op now usg two target lesions in liver liver metastasis.,biopsy from liver,received 4 grey white to grey brown linear cores measuring 1 to 1.3cm.entire tissue processed.,linear cores of liver parenchyma infiltrated by a neoplasm arranged as islands. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. areas of necrosis seen.,metastatic carcinoma biopsy from liversuggestive of metastasis from breast in a known case of carcinoma breast.
MRA145716,left chest wall lesion known case of left carcinoma breast post op.,left chest wall lesion biopsy.,received multiple greywhite linear cores measuring 0.6 to 1.2cm. entire tissue processed.,section shows tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left chest wall lesion biopsy (post op carcinoma left breast) :suggestive of recurrence of ductal carcinoma in a known and treated case of carcinoma left breast.
MRA146003,right lung mass known case of carcinoma breast post mrm.,biopsy from right lung mass,received multiple grey white linear cores measures 0.7 1cm. entire tissue processed.,section shows linear cores of lung parenchyma harboring an infiltrating neoplasm arranged in nests occasional glandular pattern and cords of neoplastic cells exhibiting increased n c ratio pleomorphic hyperchromatic nuclei occasional conspicuous nucleoli and moderate amount of pale eosinophilic cytoplasm. necrotic foci are noted.,biopsy from right lung mass:poorly differentiated malignancy metastatic in a treated case of carcinoma breast suggest ihc.
MRA146659,carcinoma breast post surgery,bronchial biopsy.,received 2 very tiny grey white soft tissue bits measures 0.2x0.1x0.1cm.entire tissue is processed.,section shows bronchial epithelium with areas of hemorrhage and crush artefacts.,bronchial biopsy:no evidence of malignancy or any specific pathology noted.
MRA146933,solid cystic lesion in left chest wall metastasis.,biopsy for left chest wall lesion.,received multiple grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows multiple linear cores with a tumor arranged in nests and sheets. the tumor cells are oval to polygonal with moderate nuclear pleomorphism hyperchromatic nuclei and moderate to abundant amount of eosinophilic to vacuolated cytoplasm. many mitotic figures are seen. focal areas show necrosis.,biopsy for left chest wall lesion:poorly differentiated carcinoma.favor metastasis in a known case of carcinoma breast.
MRA147010,liver lesion possibility of metastases,liver lesion core biopsy.,received multiple linear cores measures 0.8 1 cm. entire tissue possessed,section shows liver parenchyma with an infiltrating neoplastic lesion arranged in glandular pattern and nest.the cells have moderately pleomorphic hyperchromatic nuclei and moderate amount of cytoplasm. stroma shows fibrosis. fragment of skeletal muscle seen.,liver lesion core biopsy:metastatic carcinoma probably from breast.suggest ihc.
MRA148016,now liver lesion metastasis.,biopsy from liver lesion.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,sections studied show linear cores of liver parenchyma harboring lesion arranged in trabeculae cords acinar pattern. lesional cells are polygonal with pleomorphic large round to oval hyperchromatic nuclei inconspicuous nucleoli some cells are showing prominent nucleoli and nuclear inclusion and moderate amount of clear to eosinophilic cytoplasm. stroma shows myxoid degeneration and desmoplasia. lympho plasmacytic infiltrate also seen.,liver lesion biopsy :metastatic deposit in known case of carcinoma breast.
MRA148546,known case of carcinoma left breastleft cervical node possibility of metastasis.,left cervical node core biopsy.,received 6 grey white to grey brown linear cores measures0.4 0.5cm. entire tissue processed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left cervical node core biopsy:suggestive of metastatic carcinoma in known and treated case of carcinoma left breast.
MRA149077,old case of right carcinoma breast in 2015. now presented with skin nodules.,biopsy from right chest wall.,received single grey white to grey brown soft tissue bits altogether measuring 1x0.6x0.4cm. entire tissue processed.,linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged as cords trabeculae and tubules. the cells have high n c ratio exhibit moderate nuclear pleomorphism hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. mitotic figures are discerned.,biopsy from right chest wall :invasive carcinomasuggestive of recurrence in a known case of carcinoma breast.
MRA149293,history of carcinoma left breast post mrm status. right breast lump carcinoma fibroadenoma.,biopsy form right breast.,received multiple grey white linear cores measuring 0.3 to 0.6 cm.entire tissue processed.,linear cores of breast tissue showing fragments of stroma in a leaf life architecture lined by scattered epithelium. occasional compressed benign glandular and tubular elements are seen.,fibroepithelial lesion fibroadenoma right breast.no evidence of mailgnancy in the cores submitted.
MRA149435,old case of carcinoma right breast mrm status.now mass in left breast second primary.sternal lesion recurrence.,biopsy from sternal lesion.,received 5 grey white linear cores measuring 0.6 to 1cm.entire tissue processed.,linear cores of fibrous tissue and bony trabeculae with intervening neoplastic tissue arranged as clusters and islands. the neoplastic cells exhibiting moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm.,metastatic carcinoma biopsy from sternal lesion in known post op case of carcinoma right breast.
MRA149585,carcinoma cervix post op april 2015 and carcinoma breast post op in july 2015,biopsy vault.,received 5 grey white to grey brown soft tissue bits altogether measuring 1x0.5x0.3cm.entire tissue is processed.,fragments of a neoplasm arranged as nests and in vague papillary and glandular pattern.the lining epithelial cells are cubocolumnar exhibit nuclear hyperchromasia and pseudostratification.increased mitoses seen.,poorly differentiated carcinoma biopsy vault.
MRA149916,known case of carcinoma breast.,biopsy from right ovary.,received 5 grey white linear cores measures 0.7 to 1.0cm. entire tissue processed.,section shows linear cores of tissue harboring a neoplastic lesion arranged in cords nests papillae . the cells have round to oval hyperchromatic pleomorphic nuclei with moderate cytoplasm. intervening stroma shows scattered lymphocytic infiltrate..,biopsy from right ovary.invasive carcinoma metastaticneeds confirmation
MRA149959,known case of carcinoma left breast.,axillary lymph node biopsy.,received 8 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,the section shows fragmented linear cores of lymphoid tissue showing enlarged lymphoid follicles. no evidence of malignancy is seen.,axillary lymph node biopsy :features are suggestive of reactive lymphoid hyperplasia.
MRA149983,known case of fibrocystic disease both breasts on follow up,a) left adnexal massb) right adnexal massc) appendixd) ascitic fluid,a) received multilocuated cyst measures 8.5x5x5cm cut surface shows nocapsular breach yielded serosanguinous fluid and hemorrhagic tube measures 5.5cm no fimbrial end identifiedb) received cystic mass measures 5.5x4x2.5cm cut surface shows cystic and solid areameasures 3.0x2.5x2.5cmc) received single appendix with attached fibrofatty tissue measures 4x2x1.5cm appendixmeasures 3.5cm cut surface is unremarkabled) received 5 ml yellowish slightly turbid fluid,a) sectio0n shows ovarian parenchyma with cystic lesion lined by luteinized granulosa cells having abundant amount of eosinophilic cytoplasm and bland appearing nucleus. interspersedperipheral theca cells and corpus albicantes are noted. numerous hemosiderin laden macrophagesare seenb) section shows ovarian parenchyma with a fallopian tube lined by stratified epithelium. the stratification columnar having moderate amount of cytoplasm hyperchromatic nucleus andinconspicuous nucleoli . c) appendix shows unremarkable histology. no evidence of malignancy seen.d) ascitic fluid:smears show moderate cellular yield of loose aggregates and singly scattered reactive mesoothelialcells neutrophils and lymphohistiocytes over a hemorrhagic background,a) left adnexal mass:corpus luteal cystb) right adnexal mass:hydrosalpinx with focal proliferative changes serous tubal intraepithelial lesion (stil)suggest: ihc to rule out serous intraepithelai carcinoma (stic)c) appendix:unremarkable histiologyno evidence of malignancy in the material submittedd) ascitic fluid:no evidence of malignancy in the material submitted
MRA150230,left mrm for carcinoma breast with ct chest pleural nodule metastases.,biopsy from left pleural base nodule.,received multiple grey white to grey brown soft tissue bits measuring 0.3 0.5 cm.entire tissue processed.,linear cores of lung parenchyma with an adjacent neoplasm arranged as islands and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is scant.,metastatic carcinoma biopsy left pleural base nodule in a known case of carcinoma breast.
MRA150328,known case of carcinoma left breast.,wide local excision.,received lumpectomy specimen measures 4.5x4x2.5cm. skin ellipse measures 4.5x1.8cm. cut surface grey white soft lesion measuring 0.8x0.8x0.5cm.distance from margins :superior : 1cm.inferior : 1cm.medial : 4cm.lateral : 0.9cm.deep : 0.6cm.,tumor : the section from the tumor shows pleomorphic cells with hyperchromatic nucleus and eosinophilic cytoplasm. invasive ductal carcinoma.modified br score is 6 9.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 nuclear grade ii.lymphovascular invasion :not present.ductal carcinoma in situ not present.perineural invasion :not present.all resected margins are free of tumor.,wide local excision specimen left breast invasive ductal carcinoma.nuclear grade ii.maximum dimension of tumor : 0.8x0.8cm. lymphovascular invasion not present.ductal carcinoma insitu is not present.all resected margins are free of tumor..pathological stage : pt1n0.
MRA150385,known case of carcinoma right breast. post chemo.,biopsy from right breast.,received 5 grey white linear cores measures 0.5 0.8cm. entire tissue processed.,linear cores of breast tissue infiltrated by neoplasm arranged in clusters and nests. the neoplastic cells have vesicular to hyperchromatic nuclei and abundant eosinophilic cytoplasm.,biopsy from right breast:invasive carcinoma nst.
MRA150567,right breast lump.,right breast biopsy.,received 5 linear cores measures 0.5 to 2cm. entire tissue processed.,section studied show linear cores of fibrous tissue with an infiltrating lesion arranged predominantly in sheets. nests and focal papillary pattern. the cells are oval having moderate amount of eosinophilic cytoplasm hyperchromatic nucleus and prominent nucleoli. brisk mitotic activity is seen. stroma is desmoplastic with areas of hemorrhage and necrosis.,right breast biopsy :invasive carcinoma nst grade 3.modified bloom richardson score is 8 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9 .........
MRA151050,known case of rt beast post mrm,right infraclavicular node.,received 6 grey white linear cores measures 0.2 1cm. entire tissue processed.,section shows multiple cores of tissue harboring lesional cells are round to oval having hyperchromatic nuclei moderate nuclear pleomorphism and moderate cytoplasm. mitosis are discerned.,right infraclavicular node core biopsy :suggestive of metastatic carcinoma in a known case of carcinoma breast.
MRA151231,carcinoma breast left post neoadjuant chemotherapy.specimens:left modified radical mastectomy specimen.,received in : formalin. procedure : mastectomy post nactlaterality : lefttotal dimensions : medial to lateral : 14.5cm. superficial to deep : 2.5cm. superior to inferior :13cm.skin ellipse : 9.5x7cm.nipple : normal scar surgical defect : not seen.tumor : single.tumour size : 3.5x3x2cm. location of tumor : 4 central quadrant and 4 upper outer quadrant.margins of tumor : ill defined deep margin : 0.8cmmuscle : absent adjacent breast : fibrofatty.size of largest node : 3x2.5x1.cm cut surface shows greywhite area measuring 2.8cm,sections show breast parenchyma harboring infiltrating lesion arranged in sheets nests islands and tubules lesion comprising of round to oval cells with moderately pleomorphic vesicular nuclei and prominent nucleoli with moderate cytoplasm. adjacent stroma shows desmoplasia and lymphocytic infiltrate. mitotic figures 12 15 10 hpf. areas of solid dcis and dcis with comedonecrosis noted.lymphovascular invasion identified.perineural invasion is not identified.,left modified radical mastectomy,residual invasive ductal carcinoma grade iii status post nact.modified br score is 8 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3tumor measures 3.5cm in greatest dimension.deep margin : free of tumor.dcis present with comedonecrosis.lymphovascular invasion seen perineural spread is not seen.matted nodes are seen.4 of 4 nodal masses show tumor (4 4). extranodal spread is seen.larger measuring 3x2.5cm.
MRA151445,chest wall lesion core biopsy.,right chest wall lesion core biopsy.,received 4 grey white linear cores measuring 0.5 to 0.8cm. entire tissue processed.,section shows linear cores with cells arranged in nests and trabeculae. cells are pleomorphic with scanty cytoplasm and round to oval for hyperchromatic nuclei. with prominent nuclei. prominent retraction space present around tumor nests.,right chest wall lesion core biopsy:features are consistent with reurrence known case of carcinoma breast.
MRA151550,carcinoma left breast.,biopsy from left breast.,received multiple grey yellow linear cores measures 0.5 to 1cm. entire tissue processed,linear cores of breast tumor infiltrated by a neoplasm arranged as tubules and cords. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. the intervening stroma shows scattered lymphocytic inflammatory cell infiltrate.,biopsy from left breast.invasive ductal carcinoma grade 2modified bloom richardson score 7 9.tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
MRA151743,known case of carcinoma breast.,liver lesion core biopsy (post op ct rt carcinoma breast).,received multiple linear cores measures 1.5 to 2cm. entire tissue processed.,section shows tumor cells in sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,liver lesion core biopsy (post op ct rt carcinoma breast):positive for malignancy.suggestive of metastatic carcinoma in known and treated case of carcinoma breast.
MRA151780,known case of carcinoma breast.post bcs (4 years back).now new lesion in left breast.,biopsy from left breast.,received 4 grey white linear cores measures 1 to 1.5cm. entire tissue processed.,the section shows linear cores of breast parenchyma showing infiltration by tumor arranged in sheets nests and cords and tubules.the tumor cells are round to polygonal with increased n:c ratio pleomorphic hyperchromatic nuclei and moderate cytoplasm. intervening stroma is desmoplastic .marked crush artifact is noted.,biopsy from left breast lesion:invasive carcinoma nstmodified br score is 7 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 ...... 7 9 ......
MRA15196,carcinoma breast post chemo radio metastatic carcinoma lung.,biopsy from left lung mass.,received 4 greywhite to greybrown linear cores measures 0.5 to 0.7cm. entire tissue processed.,sections show tiny tissue cores harboring a lesion arranged in nests composed of monomorphic neoplastic cells exhibiting round to oval hyperchromatic nuclei inconspicuous nucleoli and scanty cytoplasm. the intervening stroma shows presence of extracellular mucin.,biopsy from left lung mass:the features are suggestive of metastatic deposits in a known case of carcinoma breast.possibility of associated neuroendocrine component cannot be ruled out.tissue sparse for work up.however gata 3 and hormone receptor status is being attempted
MRA152161,carcinoma breast post op with endometrial hyperplasia.,endometrial biopsy.,received multiple tiny grey white bits measures 0.5 x 0.3 x 0.2 cm. entire tissue processed.,section shows fragment of endometrial tissue with benign endometrial glands few with intraluminal secretions. stroma shows plump cells spindle cells and congested vessels. no atypia is seen.,endometrial biopsy :features suggestive of simple hyperplasia.
MRA152252,left breast mass carcinoma breast fibroadenoma..,biopsy from left breast mass.,received 3 grey white linear cores measures 1.2 to 1.4cm. entire tissue processed.,section from linear breast cores harbors infiltrative tumor arranged in diffuse sheets and tubules . the tumor cells are round to oval with hyperchromatic pleomorphic nucleus. few areas shows ductal carcinoma in situ with central comedo necrosis. mitotic figures are seen.,biopsy from left breast :invasive carcinoma.ductal carcinoma in situ with comedo necrosis.modified bloom richardson score is 6 9. grade iitubule formation : 2nuclear pleomorphism: 2mitosis figures : 2 6 9
MRA152274,known case of carcinoma breast.,biopsy from l5 spinous process.,received a linear bony fragment with blood clot that measures 00.5 0.6 cm. entire tissue processed.,section shows cores of tissue with extensive areas of hemorrhage and a lesion arranged in tubules sheets and loose clusters of cells. cells have round to oval hyperchromatic nuclei and moderate amount of vacuolated cytoplasm occasional mitotic figures noted. admixed inflammatory cells noted.,biopsy from l5 spinous process:features are suggestive of metastatic carcinoma in a known case of carcinoma breast.decalcified bone section shows tumor with similar morphology.
MRA152403,carcinoma right breast post rt with complex adnexal mass post tah.,a) right adnexal mass.b)left adnexal mass.,a) received right adnexal mass specimen of ovary measuring 3.8x2.5x2cm. attached fallopian tube measures 0.5cm.cut surface shows hemorrhagic cyst.weight 15gms.b) received left adnexal mass specimen of ovary measuring 5x3x1.5cm.externally lobulated capsule is intact.left fallopian tube 0.2cm. cut surface yielded serousanguinous fluid.weight 10 gms.,a) section shows ovarian parenchyma harboring cystic lesion filled with hemorrhage and necrotic debris. fallopian tube shows refractive material surrounded by macrophages and multinucleated giant cells.b) section shows normal ovarian parenchyma and fallopian tube.,a) right adnexal mass :hemorrhagic cyst no evidence of malignancy.b)left adnexal mass :no evidence of malignancy.
MRA152472,known case of carcinoma breast,biopsy from liver lesion.,received 6 grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,linear cores of hepatic parenchyma exhibiting a neoplastic lesion arranged in sheets an nests cords and tubular configuration demonstrating moderate to marked nuclear pleomorphism eosinophilic cytoplasm and brisk mitotic activity. adjacent liver parenchyma shows features of steatohepatitis,biopsy from liver lesion:the features are suggestive of metastatic carcinoma in a known case of carcinoma breastsuggest ihc for confirmation.
MRA152601,right breast lump .,biopsy from right breast excision.,received skin ellipse measures 2.5x1cmsurface unremarkable frank tumor not seengrey white ill defined measures 1.5x1x1cm.distance from the following margins:superior margin: 1.5cminferior margin:1.5medial margin:1cmlateral margin :1cmdeep margin :1.8cm,section shows breast parenchyma with few ducts exhibiting proliferating ducts fibroadenosis ductal carcinoma in situ solid and and cribriform pattern noted. stroma shows desmoplasia with scattered lymphomononuclear infiltrates.,right breast excision biopsy:ductal carcinoma in situ solid and cribriform pattern nuclear grade 3 with comedonecrosis invasion not identifiedlesion measures 1.5cm. in greatest dimension.all margins of section (superior inferior medial lateral and deep) are free of tumor.
MRA152647,known case of carcinoma right breast .,left breast core biopsy.,received 4 grey white soft tissue bits measures 0.5 1.5 cm. entire tissue processed.,the section shows linear cores of breast parenchyma with tumor infiltrating in sheets and nests. the tumor cells are round to oval with high n c ratio hyperchromatic markedly pleomorphic and moderate moderate cytoplasm. tumor giant cells are seen. intervening desmoplastic stroma is seen.,left breast core biopsy:invasive ductal carcinoma grade 3. modified bloom richardson score 8(3+3+2).
MRA153087,known case of carcinoma right breast post bcs,biopsy from left breast,received 5 grey white to grey brown linear linear cores measured 0.3 to 0.6cm. entire tissue processed.,sections shows breast tissue with hyperplastic ductules lined by cuboidal epithelial cells. stroma shows fibrocollagenous tissue. no atypia is seen.,left breast core biopsy :features suggestive of benign proliferative breast disease adenosis.no evidence of malignancy is seen.
MRA153510,known case of carcinoma breast.liver sol metastatic.,liver core biopsy.,received seven grey white liner core measures 1 to 1.2 cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchroamtic nuclei and moderate amount of cytoplasm.,liver core biopsy :suggestive of metastatic carcinoma in known case of carcinoma breast.
MRA153874,carcinoma lunghistory of carcinoma left breast in 2015.,biopsy from right lung,received multiple grey white to grey brown linear cores measures 1 to 1.5cm.entire tissue is processed.,linear cores of lung parenchyma infiltrated by a neoplasm arranged in acinar and trabecular pattern. the lining epithelial cells are cubocolumnar have hyperchromatic nuclei and moderate cytoplasm.the intervening stroma is desmoplastic.,invasive carcinoma biopsy from right lung primary metastaticsuggest ihc.
MRA154232,multiple lung nodule likely metastases known case of carcinoma right breast.,biopsy from lung nodule.,received 3 greywhite to grey black linear cores measuring 0.5 to 1cm. entire tissue processed.,linear cores of lung parenchyma exhibiting sheets and nests of round to oval neoplastic cells demonstrating moderate nuclear pleomorphism and eosinophilic cytoplasm. mitotic figures are discerned. intervening fibrocollagenous stroma shows lymphoplasmacytic infiltrate.,biopsy from lung nodule:metastatic ductal carcinoma in known case of carcinoma breast.suggest ihc.
MRA154306,known case of carcinoma breast.multiple liver lesion p o metastasis.,liver core biopsy.,received multiple grey white to grey brown linear core measures 1 to 1.5cm. entire tissue processed.,section shows cores of liver tissue infiltrated by tumor cells in nests cords and tubules. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,liver core biopsy :positive for malignancy.suggestive of metastatic carcinoma most possible from breast.
MRA154379,nodular lesion in both lungsk c o carcinoma left breast with brain metastasis.,lung lateral not specified biopsy.,received multiple grey white to grey brown linear core measures 0.5 to 0.8cm. entire tissue processed.,section studied shows multiple fragments of lung parenchyma and focal respiratory epithelium with an infiltrating lesion arranged in nests cords and vague glandular pattern. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli mitotic figures are discerned. stroma is desmoplastic with areas of hemorrhage.,lung lateralilty not specified biopsy :the features favor metastatic deposits in a known case of carcinoma breast. please await report on ihc to rule out primary.
MRA154906,known case of carcinoma breast ( post op).,biopsy from left breast lump,received 5 grey white to grey brown linear core measures 0.8 to 1.2cm. entire tissue processed.,section show cores of breast tissue with on invasive neoplasm composed of sheets and nests glands and cords of cells having a c ratio moderate eosinophilic to clear cytoplasm. there moderate nuclear atypia and increased mitosis.,biopsy from left breast lump:suggestive of invasive carcinoma ductal type (nos)modified bloom richardson score is 8 9 grade iiitubule formation : 3nuclear pleomorphism : 2mitosis : 3 8 9
MRA155768,carcinoma breast post op.,liver sol biopsy.,received 3 grey white to grey brown linear cores measuring 0.8 to 1cm. eire tissue processed.,sections show linear cores harboring liver parenchyma. focal atypia present with mild alteration of nucliocytoplasmic ratio and hyperchromasia in few of the hepatocytes.,liver sol biopsy :no definite evidence of malignancy in the section studied.
MRA156139,carcinoma left breast post ct surgery rt.,left chest wall skin nodule.,a) received 2 skin covered soft tissue bits larger bits measuring 1.5 x 1.4x 0.6cm. entire tissue processed.smaller bit measuring 1.4x1x0.6cm. entire tissue processed.,section shows fragments of fibroadipose tissue harboring a lesion arranged as nests tubules and cords of round to oval cells with vesicular nucleus prominent nucleoli and scanty to moderate cytoplasm. few cells shows hyperchromatic pleomorphic nucleus and scanty cytoplasm.,left chest wall skin nodule:invasive carcinoma.suggestive of recurrence in a known case of carcinoma breast post mrm.
MRA15637,chest wall recurrence post modified radical mastectomy and c7 r7.,left chest wall mass wedge biopsy.,received single grey white to grey brown soft tissue bits measures 1.5 x 0.8 x 0.5cm. entire tissue processed.,section show ulcerated skin with infiltrating lesion arranged in sheets cords and vague acini. the lesional cells are hyperchromatic with moderate cytoplasm. intervening stroma shows lymphoplasmacytic infiltrate.,left chest wall mass wedge biopsy :suggestive of recurrence of carcinoma in known and treated case of carcinoma breast.
MRA156835,known case of carcinoma.breast post op liver lesions metastasis.,left lung biopsy.,received multiple fragments linear core measures 0.2 1cm. entire tissue processed.,section studied show linear areas of fibrous tissue with an infiltrating lesion arranged in nests and islands. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and inconspicuous nucleoli. mitotic figures are discerned. stroma is desmoplastic with extensive areas of hemorrhage and necrosis.,left lung biopsy:poorly differentiated carcinoma case of carcinoma breast.
MRA156844,known case of carcinoma breast.multiple small liver space occupying lesions metastasis.,biopsy from liver.,received 6 grey white to grey brown linear cores measuring 1 to 1.3cm.entire tissue processed.,linear cores of liver parenchyma infiltrated by a neoplasm arranged as clusters and islands. the lesional cells exhibit nuclear hyperchromasia and have moderate cytoplasm. mitotic figures are discerned. lymphovascular emboli seen.,metastatic carcinoma biopsy from liver in a known case of carcinoma breast.
MRA157338,right chest wall lesion.,right chest wall biopsy.,received 4 grey white linear core measures 1 to 1.5cm. entire tissue processed.,section studied shows linear cores of fibrous tissue harboring an infiltrating lesion arranged in cords and nests. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few. mitotic figures are discerned. stroma is desmoplastic with areas of hemorrhage and necrosis.,right chest wall biopsy :recurrence of disease in a known case of carcinoma breast.
MRA157809,known case of carcinoma breast,biopsy from cerebellar lesion.,received fragments of grey white tissue measures 2x1x0.5cm. entire tissue processed.,section studied show cerebellar parenchyma infiltrated by a neoplastic lesion arranged in sheets islands composed of cells showing moderate pleomorphism round to oval vesicular nuclei and moderate eosinophilic cytoplasm. few cells show prominent nucleoli. areas of hemorrhage and hyalinisatuion. noted.,biopsy from cerebellar lesion:metastatic carcinoma in a known case of carcinoma breast.
MRA157947,known case of carcinoma breast.right axillary node.,right axillary lymph node.,received four linear cores measures 0.3x0.4cm. entire tissue processed.,section shows multiple fragments showing a lesion arranged in sheets. the cells are round to oval hyperchromatic nuclei. scant cytoplasm inflammatory infiltrates composed of lymphocytes and histocytosis. tingible body macrophages are seen.,right axillary lymph node :no metastases seen in the core biopsy.suggest intoto excision of the lymph node for further confirmation or to rule out lymphoproliferative disorder if clinically deemed necessary.
MRA157968,known case of carcinoma right breast post mastectomy now anterior mediastinal mass.,biopsy from anterior mediastinal sternal mass,received multiple grey white linear cores measures 0.6 to 0.8cm. entire tissue is processed,fragmented linear cores of tissue exhibiting diffuse proliferation of round to oval cells demonstrating moderate to marked nuclear pleomorphism and eosinophilic cytoplasm. mitotic figures are discerned. intervening areas shows desmoplastic stroma with lymphoplasmacytic infiltrate.,biopsy from anterior mediastinal sternal mass:suggestive of deposits of poorly differentiated carcinoma in a known case of carcinoma breast.
MRA158337,left breast carcinoma with bone metastatsis diagnosed in august 2015.,left modified radical mastectomy post nact.,received in : formalinprocedure : mastectomy post nact laterality : lefttotal dimensions : medial to lateral 19cm. superficial to deep 5.5cm. superior to inferior 16cm.skin ellipse :14x10cm. nipple :normal scar surgical defect : not seen.tumor : singletumour size : 6.5x6.5x4cm. location of tumor : upper outer quadrant.margins of tumor : ill defined. deep margin : 1cm.muscle : absent adjacent breast : fibrofatty tissue. axillary tail :7x5x3cm.size of largest node :3x3x2cm cut surface deposit.,section from tumor shows breast parenchyma infiltrated by neoplasm arranged as islands and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. areas of necrosis seen. lymphovascular emboli seen.sections from nipple and areola : free of tumor.sections from deep margin : free of tumor.7 22 lymph nodes from left axillary dissection show metastatic deposits of tumor .perinodal spread is seen.,left breast left modified radical mastectomy :invasive ductal carcinoma grade 3.modified br score is 8 9.tubule formation : 3.nuclear pleomorphism : 3.mitotic figures : 2.tumor measures 6.5cm in greatest dimension and is located in the upper outer quadrant.ductal carcinoma in situ seen ( high grade comedo pattern).lymphovascular invasion seen.perineural invasion not seen.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes :22 lymph nodes metastasis : 7 ( 7 22).perinodal spread seen.summary :left mrm invasive grade 3.22 lymph nodes metastasis : 7 ( 7 22).perinodal spread seen.
MRA158410,known case of carcinoma right breast.,right lung lesion biopsy.,received 6 grey white linear cores measures 0.5 to 1.0 cm. entire tissue processed.,section shows cores of lung parenchyma with a lesion arranged in nests and sheets. the cells have hyperchromatic nuclei with moderate amount of nuclear pleomorphism and moderate cytoplasm. stroma shows lymphocytic infiltrates.,right lung lesion biopsy:the features favor metastatic carcinoma in a known case of carcinoma right breast.suggest ihc for gata3.
MRA158655,carcinoma breast post op lung nodule metastasis,right lung biopsy.,received multiple grey white to grey brow linear cores measures 0.6 0.8cm. entire tissue processed.,section show linear cores of tissue harboring a neoplastic lesion arranged in nests tubules. the cells have moderately pleomorphic round hyperchromatic nuclei and moderate amount of pale eosinophilic cytoplasm. large areas of necrosis noted. mitotic figures discerned. stroma shows fibrosis..,right lung biopsy:metastatic carcinoma in a known case of carcinoma breast.
MRA158715,carcinoma left breast mrm 2012post operative ct and rt had chest wall recurrence sep 2015fdg pet ct sep 2016 now nodule chest wall.,biopsy from chest wall nodule,received single grey white skin covered soft tissue measures 1x1x0.8cm. entire tissue is processed.,fragment of skin with underlying dermal collagen harboring occasional islands of atypical cells with hyperchromatic to vesicular nuclei inconspicuous nucleoli and vacuolated cytoplasm. surrounding lymphoplasmacytic inflammatory cell infiltrate seen.,atypical cell clusters biopsy from chest wall nodule.
MRA159108,carcinoma left breast post chemotherapysclerotic right iliac bone lesion metastasis,biopsy from right iliac bone lesion,received multiple bony fragments measures 0.6 to 0.8cm. entire tissue is processe,section shows multiple sclerotic bony bits and occasional bony trabeculae with bony osteocytes,right iliac bone lesion biopsy:no cellular elements seenno opinion possible
MRA159212,carcinoma left breast.,chest wall nodule biopsy. left mrm site,received skin covered nodule measuring 1.5x1x0.6cm.cut surface grey white nodule measuring 0.8x0.4x0.4cm.,section show epidermis and dermis with a cellular infiltrating into the epidermis. the cells are arranged in cords and clusters having ovoid cells with moderate amount of cytoplasm hyperchromatic to vesicular nucleus with prominent nucleoli in few. mitotic figures are discerned. stroma shows desmoplasia with ares of hemorrhage.,chest wall nodule biopsy :recurrent ductal carcinoma infiltrating the overlying skin in a known case of carcinoma left breast.
MRA159308,history of left breast carcinoma(post mrm status).multiple lesions in right breast carcinoma.,right breast (retroareolar) core biopsy.,received 3 grey white linear cores measuring 1 to 1.2cm.entire tissue processed.,section show cores of breast parenchyma harboring neoplastic lesion arranged in cords and sheets. individual cells exhibit moderate nuclear pleomorphism with round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma is fibrous with inflammatory cells. crush artefacts seen.,right breast core biopsy :invasive ductal carcinoma right breastmodified br score is 7 9 grade iiitubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MRA159413,hypoechoic lesion in left breast suspicious.,biopsy from left breast lesion.,received 7 grey white to grey brown linear cores measuring 0.4 to 0.8cm. entire tissue is processed.,fragmented linear cores of breast parenchyma demonstrating focal dysplasia aggregates of round to oval neoplastic cells exhibiting moderate nuclear pleomorphism and pale eosinophilic cytoplasm . there are foci of necrosis. intervening areas show fibrocollagenous stroma.,biopsy from left breast lesion. high grade ductal carcinoma in situ with comedonecrosis.no invasive component seen in the cores submitted.
MRA159608,carcinoma right breast post nact.,a) right breast wide local excison.b) right axillary level i and ii lymph node dissection.,a) fresh tissue received : yesnumber of specimens received : 1laterality : rightprocedure : wide local excision.specimen orientation : not orientated orientated superior (single white) inferior (double white) medial(single black) lateral (double black)specimen size : 5.5x4.5x4 cm skin : present skin dimensions : 2.8x0.7 cm skin abnormalities : absent nipple : absent lesion(s) : absentnumber of macroscopically visible lesions : areas of necrosis identified measuring 1x0.6x0.5cm.distance of lesion from margins : superior 0.5 cm inferior 3.0 cm medial 2.0cm lateral 0.5cm deep 3.0cmb) received fibrofatty tissue measuring 8x7x3cm largest lymph node measuring 2x0.8x0.7cm.,section shows small focus of residual tumor cells. individual cells have hyperchromatic nuclei prominent nucleoli and moderate amount of cytoplasm. lymphovascular or perineural invasion are not seen.treatment related changes including necrosis foamy macrophages and lymphocytes are seen.,a) right breast wide local excision(post nact) :residual invasive ductal carcinoma definite response to presurgical therapy is seen. small tumor focus is seen measuring 0.3 cm in greatest dimension. treatment related changes are seen. lymphovascular or perineural invasion are not seen. all margins of resection are free of tumor.b) right axillary level i and ii lymph node dissection :nine lymph nodes are identified negative for malignancy(0 9).pathological stage: ypt1an0
MRA159774,carcinoma breast post rt liver lesion metastasis.,biopsy from liver.,received 4 grey white to grey brown linear cores measures 0.7 1cm. entire tissue processed.,section shows linear cores of liver parenchyma infiltrated by neoplasm arranged in cords and nests. the cells have pleomorphic round to irregular nucleus and moderate cytoplasm. mitosis is discerned.,biopsy from liver:metastatic carcinoma in a known case of carcinoma breast.
MRA159788,known case of bilateral carcinoma breast.left breast nodule residual carcinoma.,left breast core biopsy.,received multiple grey white to grey brown linear cores measures 1 1.2 cm. entire tissue is processed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MRA160531,known case of carcinoma breast post left mrm.now liver lesion metastatic.,liver lesion biopsy.,received multiple grey brown linear cores measures 1.5 to 2cm. entire tissue processed.,sections studied from the linear core biopsy bits show tumor arranged as nests sheets composed of round to polygonal cells with scant to moderate eosinophilic cytoplasm and hyperchromatic nucleus. atypical mitosis and foci of necrosis are seen. stroma shows fibrosis and lymphomononuclear infiltrate.,liver lesion biopsy.metastatic deposits in a known case of carcinoma breast.report on ihc to follow.
MRA160578,known case of carcinoma breast po breast conservative surgery.,uterus cervix and bilateral adnexa hysterectomy with bilateral salpingo oophorectomy.,fresh tissue received : yes. procedure : total hysterectomy with bilateral salpingo oophorectomy. uterus dimensions: midline fundal serosa to ectocervix : 7.5 cmmaximum intercornual : 7 cmmaximum anterior to posterior: 5 cmcervix dimensions : 3 x 3 cm ( anterior posterior x transverse)vaginal cuff : absent.cervix shape : unremarkable.right ovary : present 3x2.5x1cm cut surface : unremarkable.left ovary : present 3x2x1cm cut surface : unremarkable.right fallopian tube : present 5cm fimbrial end identified.left fallopian tube : present 5cm.right parametrium : 1x0.5x0.5cmleft parametrium : 0.8x0.5x0.5 cmendometrium description:endometrial thickness : 0.3 cmmyometrium description:myometrial depth : 1.5cm.representative sections are submitted.,sections from cervix show chronic papillary endocervicitis.section from endometrium shows non secretory phase.bilateral ovary and bilateral fallopian tubes shows unremarkable histology.,uterus cervix and bilateral adnexa hysterectomy with bilateral salpingo oophorectomy :cervix : chronic papillary endocervicitis.endometrium : proliferative endometrium.right and left ovary: unremarkable.right and left fallopian tubes: unremarkable.right and left parametrium : negative for malignancy.
MRA161127,known case of carcinoma left breast post mrm,biopsy from right axillary tail,received 3 grey white linear cores measure 1 1.5cm. entire tissue processed.,section shows linear cores of tissue showing infiltration by tumor . tumor cells are arranged in cords occasional nests sheets and rare tubules . the tumor cells are cuboidal to polygonal with high n c ratio hyperchromatic pleomorphic nuclei and moderate amount of eosinophilic cytoplasm. areas of necrosis is seen.,biopsy from right axillary tail:invasive carcinoma favor ductal origin.modified bloom richardson score tubule formation 3nuclear pleomorphism 2mitotic figures 1 6 9grade 2
MRA161239,known case of carcinoma right breast status post surgery.now complaining of lump at the surgical site.,biopsy from right side of anterior chest wall.,received 4 grey white linear fragments measuring 0.4 to 0.5cm.entire tissue processed.,linear cores of fibrous tissue infiltrated by a neoplasm arranged as clusters and islands. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm.lymphovascular emboli seen.,invasive carcinoma suggestive of recurrence in a known case of carcinoma right breast biopsy from right side of anterior chest wall.
MRA161279,carcinoma left breast.,a) left modified radical mastectomy.b) radical adnexal mass.c) left adnexal mass.d) trachelectomy pelvic peritonectomy.e) total omentectomy.,received in : formalin.time of receipt at lab : 5:30pm.procedure : mastectomy mrm. laterality : left breast. total dimensions : medial to lateral:14cm superficial to deep:2.5cm. superior to inferior:11cm.skin ellipse : 13x8.5cm. nipple : normal scar surgical defect : not seen.tumor : : singletumour size : 0.6x0.5x0.5cm.location of tumor : upper outer quadrant. margins of tumor : ill defined. deep margin : 2cm.muscle : present. adjacent breast : fibrofatty. total number of nodes : 14 size of largest node : 1x0.5x0.5cm cut surface is greywhite.axillary tail : 6x4x1.5cm.b) received adnexal mass 7.5x4.5x3.5cm.suface is nodular no capsular breach seen cut surface:solid greywhite area measuring 4x3.5x2cm.cystic area yielded yellowish fluid. fallopian tube see attached measuring 5cm cut surface shows obliteration of the lumen.c) received left adnexal mass measuring 9.5x4.5x2cm.suface nodular no capsular breach seen.cut surface shows solid area measuring 5x3x2.5cm.fallopian tube not identified.cystic area yielded yellowish fluid.d) received cervical stump measuring 3.5x3x2.5cm.attached segment of peritoneum measuring 4x2x1cm shows cystic area measuring 2x1.5x1cm yielded clear fluid. cervix is grossly:unremarkable.e) received fibrofatty tissue measuring 40x10x1cm.multiple greybrown to greyblack nodular areas present.larger one measuring 2x1.5x1cm.,a) left modified radical mastectomy:multiple sections reveal breast parenchyma demonstrating small nodular deposit of neoplastic cells exhibiting round to ovoid cells with moderate to marked nuclear pleomorphism and eosinophilic cytoplasm.there are also myxoid areas.surrounding areas show prominent lymphocytic infiltrate.adjacent breast parenchyma is unremarkable.lymphovascular invasion and perineural invasion is not identified.deep margin is free of tumor.nipple and areola is unremarkable.14 left axillary lymph nodes are negative for malignancy.b) right adnexal mass:multiple sections reveal ovarian parenchyma exhibiting small foci of residual neoplastic cells consisting of ovoid cells demonstrating vesicular nuclei and eosinophilic cytoplasm.fallopian tube also shows small focal deposits of neoplastic cells.there is extensive areas of therapy related changes with necrosis aggregates of foamy macrophages fibrosis and hemosiderin laden macrophages.c) left adnexal mass:multiple sections exhibit small foci of residual neoplastic cells consisting of nests of ovoid cells demonstrating moderate to marked atypia.there are extensive areas of necrosis fibrosis aggregates of foamy macrophages hemosiderin laden macrophages.fallopian tube is not identified.d) tachelectomy with pelvic peritonectomy:sections from the cervix show features of chronic cervicitis.sections from pelvic peritoneum show fibrocollagenous tissue with areas of hemorrhage and congested vascular channels.e) total omentectomy: sections reveal fibrofatty tissue with small deposit of ovoid neoplastic cells.3 lymph nodes isolated are negative for malignancy(0 3).,histopathologic examination:left breast modified radical mastectomy: deposit of poorly differentiated malignancy. suggest ihc.tumor measures 0.5cm in greatest dimension and is located in the upper outer quadrant. lymphovascular invasion and perineural invasion are not identifiedposterior resection margin is free of tumor nipple and areola are free of tumor.lymph nodes: 14 lymph nodes negative for malignancy (0 14).summary : left mrm no nodal metastasis (0 14).poorly differentiated malignancy.suggest ihc.
MRA161295,known case of carcinoma right breast.,left supraclavicular lymph node.,received 3 grey white linear cores measures 1 1.2cm. entire tissue processed.,section show tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclear and moderate amount of cytoplasm.,left supraclavicular lymph node:metastatic carcinoma most possible from breast.
MRA161350,known case of carcinoma ge junction.,a) lump left upper outer quadrant.b) lumpectomy left 9 o clock,a) received single fibrofatty tissue measuring 4.5x3.5x2.5cm.cut surface shows two well circumscribed firm grey white nodules with slit like spaces. larger one measuring 1.3x0.8x0.8cm.distance from nearest inked margin is 0.3cm.smaller one measuring 0.8x0.5x0.5cm.distance from nearest inked margin is 0.1cm.distance between nodules is 1.2cm.b) received single fibrofatty tissue measuring 5x2.5x1.5cmcut surface shows a circumscribed lesion measuring 1.3x1.5x1.2cm. gritty to cut.distance from nearset inked margin is 0.1cm.,a) sections from both nodules show breast parenchyma incorporating a fairly circumicribed lesion composed of variably cellular spindle cell stroma in which benign cleft like and tubular glandular elements are present. these glandular elements are composed of single basal cell and single luminal cell large.b) section show breast parenchyma incorporating a well circumsubed hyalinised nodule.,a) fibroadenoma lump left upper outer quadrant.b) fibroadenoma with extensive hyaline change lump 9 0 clock.
MRA161408,know case of carcinoma right breast. discharging sinus from chest wall wound.,sinus tract excision.,received skinn covered fibrofatty tissue measures 4x2.5x2 cmskin measures 3x1.5 cm surface shows depression measures 0.5 x0.5 cm. sinus vaguly identified.,section shows stratified squamous epithelium with ulceration. subepithelium shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. background shows marked lymphocytic infiltration and congested capillaries.,sinus tract excision: suggestive of tumor deposit is a known and treated case of carcinoma breast.
MRA161506,skin nodule in a case of carcinoma breast,biopsy of the skin nodule,received single skin covered fibrofatty tissue measures 1x0.8x0.6cm. entire tissue is processed,section shows skin with unremarkable epidermis. the dermis shows extensive fibrosis and hyalinisation,no evidence of malignancy in the material submitted
MRA161736,known case of carcinoma right breast.,wide local excision breast.,received lumpectomy specimen measuring 6.5x6x2.5cm. skin ellipse measures 3.5x1.5cm. surface shows a linear scar measuring 1.5cm. cut surface shows few cystic spaces with cheezy oozing material altogether measuring 2x1.5x1.5cm.distance from margins :superior : 0.6inferior : 2cm.medial : 2.5cm.lateral : 1.2cm.deep : 1cm.,multiple section shows dense fibrous tissue with cystic spaces showing inflammatory cells consisting of lymphocytes plasma cells and histiocytes in proteinaceous material. there is no evidence of atypical cells or malignant cells. all resected margins show fibrocollagenous tissue and are free of tumor.,wide local excision breast(nodule underneath scar) :fibrosis and inflammatory cells.no evidence of malignancy resected margins show fibrocollagenous tissue and are free of tumor.
MRA161899,known case of carcinoma right breast post bcs.,biopsy from right breast lesion.,received six grey white to grey yellow linear cores measures 1 to 1.2cm. entire tissue processed.,linear cores of tissue exhibiting sheets cords nests of round to oval neoplastic cells showing moderate to marked nuclear pleomorphism and eosinophilic cytoplasm with intervening desmoplastic stroma and areas of necrosis.,biopsy from right breast lesion :invasive carcinoma in known case of carcinoma breastmodified br score is 8 9 grade iii.tubular formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
MRA162458,carcinoma left breast(post nact).,left breast.,received in : formalintime of receipt at lab : 5pm 28 06 16.procedure : mastectomy laterality : left. total dimensions : medial lateral : 20cm. superficial deep : 5cm superior inferior: 17.5cm skin ellipse : 18x18.5cm. nipple : normal scar surgical defect : surface of skin shows nodularity and ulceration in the upper outer quadrant measuring 11x10.5cmtumor : singlelocation of tumor : upper outer quadrant. tumour size : 10.5 x 10 x 7 cm. cut surface lobulated greywhite with areas of necrosis. margins of tumor : circumscribed deep margin : 0.4 cm.muscle : 9 x 5 cm.adjacent breast : fibrofatty. axillary tail : 7 x 4.5 x 2 cm.size of largest node : 3 x 2 x 1 cm.cut surface is greywhite.,section shows tumor cells in diffuse sheets and nests.individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast left modified radical mastectomy(post nact) :residual invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2). tumour is located in the upper outer quadrant. tumor measures 10.5 cm in greatest dimension. ductal carcinoma in situ component is not identified. lymphovascular invasion is indeterminate. perineural invasion is not identified. overlying skin is involved by tumour with ulceration. posterior resection margin is free of tumor. nipple and areola is free of tumor.lymph nodes : two out of seventeen lymph nodes shows metastatic tumour deposits(02 17). size of the larger tumour deposit measures 0.4 cm in greatest dimension. no extranodal extension is identified.pathological stage : ypt4bn1a
MRA162535,left breast mass.,core biopsy of left breast mass.,received multiple grey white to grey brown linear cores 0.8 to 1.0cm entire tissue is processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as cords clusters and tubules.the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic to vesicular nuclei conspicuous nucleoli and moderate cytoplasm.areas of necrosis seen.,biopsy from left breast:infiltrating ductal carcinoma mbr score is 6 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures:1
MRA162680,known case of left carcinoma breast relapsed.,biopsy from left breast lump.,received grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm in trabeculae and nests. the neoplastic cells. show increased n:c ratio moderate nuclear pleomorphism and increased n:c ratio. stroma is desmoplastic.,breast biopsy (left)invasive carcinoma nst.suggestive of recurrence.mbr score (3+2+2) 7 9.
MRA162774,left breast lump carcinoma breast.,biopsy from left breast lump.,a) received 3 grey white to grey brown linear cores measures 1 to 1.4 cm. entire tissue processed.,sections show linear core of tissue with a lesion arranged in papillary pattern cords and sheets. individual cells have round to oval eccentrically placed round to oval hyperchromatic nuclei and moderate to abundant amount of eosinophilic cytoplasm. stroma show fibrosis with scattered inflammatory cells.,biopsy from left breast lump:apocrine neoplasm.suggest larger biopsy to look for invasion.
MRA163344,small right breast lesion carcinoma right breast.,right breast biopsy.,received multiple linear core measuring 0.4 to 0.6cm. entire tissue processed.,section shows extensive areas of hyperinflation with areas of necrosis. there is also presence of multinucleated giant cell at a focal area.,right breast biopsy:no evidence of malignancy in the cores submitted.
MRA163484,known case of carcinoma left breast.,biopsy from left pelvic lesion.,received multiple linear cores measures 0.6 to 0.8cm. entire tissue processed.,linear cores of fibrous tissue harboring spindle cells with relatively bland nuclei and scant cytoplasm.,spindle cell neoplasm fibroma.
MRA163576,a) carcinoma left breast post op right axillary node mets.b) carcinoma left breast post op left chest wall lesion deposit.,biopsy from right axillary and left chest wall lesion.,a) received 3 grey white linear core measuring 0.8 to 1.2 cm.entire tissue processed.b) received 3 grey white to grey yellow linear core measuring 1 to 1.2 cm.entire tissue processed.,section shows from the right axillary lymphnode and the left chest wall lesion shows cores of tissue infiltrated by nest cords and sheets of tumor cells. the neoplastic cells show hyperchromatic nuclei depicting moderate pleomorphism. cytoplasm is moderate in amount. mitotic figures discerned .occasional foci shows necrosis.,metastatic deposit in a known case of carcinoma breast right axillary and left chest wall lesion.
MRA163955,carcinoma bilateral breast post op on hormonal therapy now with right neck nodes.,biopsy from right cervical lymphadenectomy,received fibrofatty tissue measures 2x1.5x0.5cm. entire tissue processed.,section shows lymph nodal tissue showing infiltration by sheets and nests of atypical cells with moderate cytoplasm large vesicular nuclei and prominent nucleoli. extra nodal spread present.,metastatic carcinomatous deposits in a known case of breast 3 out of 7 nodes shows deposits largest deposit measures 0.7cmextranodal spread present.
MRA164148,left breast cancer (metachronouos contralateral).,a) left breast conservative surgery wide local excision.left sentinel lymph node biopsy.b) hot node.c) blue + hot node.d) non blue non hot node.e) left revised deep margin.,a) received skin covered fibrofatty tissue measures 9x7x5cm. skin ellipse 4.5x0.5cm. cut surface grey white lesion measures 2.5x2x1.5cm.distance fro the margins:superior margin 1cm.inferior margin 1.5cm.medial margin 4.5cm.lateral margin 4.5cm.deep margin 2cm.b) received single lymph node measures 0.4x0.4cm. entire tissue processed.c) received single lymph node measures 1x0.5x0.5cm. entire tissue processed.d) received fibrofatty tissue measures 2x1x0.5cm. no definite lymph node isolated.e) received fibrofatty tissue measures 3x0.5x0.5cm. stitch identified.,a) sections from left breast conservative surgery shows tumor tissue arranged in lobules separated by fibrous septa. lobules show glands and nests of neoplastic cells with abundant clear to eosinophilic cytoplasm round nucleus prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with inflammatory infiltrate composed of lymphocytes and plasma cells. lymphovascular invasion and perineural invasion are not identified. all the resected margins (superior inferior medial lateral and revised deep margin) are free of tumor.b) section from left sentinel lymph node biopsy (hot node) shows two lymph nodes. both are free of tumor (0 2).c) section from sentinel lymph node biopsy (blue + hot node) shows one lymph node and it is free of tumor (0 1).d) section from left sentinel lymph node biopsy (non blue non hot node) shows only mature adipose tissue and fibrocollagenous tissue. no lymph node identified.e) section from left revised deep margin shows adipose tissue. negative for malignancy.,a) left breast conservative surgery wide local excision:left breast invasive ductal carcinoma.grade 2.invasive component measures 2.5cm in greatest dimension.modified bloom richardson score is 7 9.tubular formation 3.nuclear pleomorphism 2.mitotic activity 2. 7 9 ductal carcinoma in situ not identified.lymphovascular invasion is not identified.perineural invasion is not identified.all the resected margin (superior inferior medial and lateral) free of tumor.revised deep margin is free of tumor.left sentinel lymph node biopsy.b) hot node:identified two lymph nodes none show metastatic deposit of tumor (0 2).c) blue + hot node:identified one lymph nodes. it is free of tumor (0 1).d) non blue non hot node:no lymph nodes identified. only fibroadipose tissue free of tumor.e) left revised deep margin:negative for malignancy.summary:left breast invasive ductal carcinoma grade 2.
MRA164524,carcinoma right breast post bcs post ct rt with metastatic skin deposits.,skin nodule back biopsy.,received one skin covered soft tissue bit measures 1 x 0.8 x 0.5 cm. entire tissue processed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,skin nodule back biopsy :suggestive of metastatic carcinoma in known and treated case of right breast.
MRA164658,known case of carcinoma breast.,a) wide excision of the scar. b) granulation tissue in the cystic cavity.,a) received fibrofatty mass with skin flap. altogether measures 18x8x5cm. skin flap measures 17x5cm. skin flap measures 17x5cm. skin surface shows a scar measures 12x0.3cm. ( surgical defect)cutsurface 10 regular fibrotic well with goity areas breast and 3 nodules noted an scar.distance from margins : superior margin: 0.8cminferior margin : 0.3cmmedial margin :10.5cmlateral margin : 2.5cmdeep margin : 0.2cmb) granulation tissue in the cystic cavity. received multiple grey white soft tissue bits with high and goitty areas altogether measures 3x2x1cm. entire tissue processed.,sections from nodules at scar site show a lesion in subepidermal region with cells in clusters cords and trabecule. the cells have scant cytoplasm pleomorphism pleomorphic hyperchromatic nuclei with prominent nucleoli in few. atypical mitosis discerned. stroma is desmoplastic. epidermis is free of tumor.,a) wide excision of scar with excision of cyst in lateral end of scar. nodule at scar site recurrence in a known case of carcinoma right breast. largest nodule measures 1cm. lymphovascular invasion seen. cyst : giant cell reaction with chronic granulation tissue. b) granulation tissue in cyst cavity fibrocollagenous tissue. no evidence of malignancy.
MRA164889,left breast mass carcinoma breast.,left breast mass core biopsy.,received multiple grey white to grey brown linear cores measures 1 to 1.2 cm. entire tissue processed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast mass core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MRA164898,carcinoma right breast(post nact).,right mrm.,received in : formalin. procedure : modified radical mastectomr (mrm.) laterality : right.total dimensions : medial lateral : 21cm superficial deep: 6cm. superior inferior : 19cm.skin ellipse : 14x7cm.nipple : nipple areola retracted. skin shows puckering (peau de orange) with ulceration measuring1x0.5cm.which is 1.5cm lateral to nipple areola complex. scar surgical defect : not seen.tumor : : single.tumour size : 3.5x2.5x2cm.location of tumor : central quadrant outer quadrant extending onto skin surface.margins of tumor : infiltrative. deep margin : 2cm.muscle : present. adjacent breast : fibrofatty.size of largest node : 1x1x1cm cut surface: fatty infiltration.axillary tail : 5x5x4cm.,h e section shows breast parenchyma with skin with a cellular lesion arranged in nests cords trabeculae and sheets.cells are pleomorphic with hyperchromatic to vesicular nucleus with irregular nuclear contours.stroma with prominent nucleoli and moderate to scanty eosinophilic to granular cytoplasm. extracellular mucin is noted.mitotic figures discerned 2 3 hpf.stroma shows desmoplasia and myxoid change congested blood vessels seen along with foci of necrosis.lymphovascular invasion is noted.perinodal invasion is not identified.tumor is seen eroding the skin.,right breast with axillary lymph node right mrm(post nact):infiltrating ductal carcinoma grade 3.mbr score is 3+2+3(8 9).tumor measures 3.5cm in greatest dimension.ductal carcinoma in situ: present (comedonecrosis).lymphovascular invasion: identified.deep margin is free of tumor.nipple and areola: unremarkable.skin is involved by the tumor.lymph nodes: 11 nodes identified.four out of eleven lymph nodes show tumor deposits(4 11).perinodal spread is identified.
MRA165313,known case of carcinoma rectum post surgery and chemotherapy.now complaining of lump in right breast. mammo usg fibroadenoma in right breast,biopsy from right breast,received 2 tiny grey white tissue fragments altogether measuring 0.3 x 0.2 x 0.2 cm.entire tissue processed.,section shows occasional ductules lined by cuboidal epithelium in a fibrocollageous stroma. no atypia seen.,right breast lump biopsy :shows few ductules suggestive of benign breast tissue.no definite evidence of invasive malignancy.suggest excision of the lump for further confirmation.
MRA165498,known case of carcinoma breast,liver lesion biopsy.,received 3 grey white linear cores measures 1.5 2cm. entire tissue processed.,section show linear cores of liver parenchyma harboring tumor infiltrating as nests and sheets composed of polygonal cells with hyperchromatic pleomorphic nucleus marked pleomorphism and moderate eosinophilic to clear cytoplasm. foci of necrosis seen.,liver lesion biopsy:suggestive of metastatic deposit in a known case of carcinoma breast.
MRA165776,carcinoma right breast.,a) right breast lump wide local excision.b) right axillary lymph node.,a) received lumpectomy specimen measuring 6x4.5x4cm.skin ellipse measuring 4.5x1.5cm on serially section shows an illdefined yellowish area measuirng 0.5x0.5x0.5cm.adjacent breast shows elastotic greywhite area.located at the following distances from respective margins: superior margin 2cm.inferior margin 0.8cm.medial margin 2cm.lateral margin 2cm.deep margin 0.9cm.grossly no tumor seen.greywhite fibrotic area seen.b) received fibrofatty tissue measuring 11x6.5x1.5cm.largest lymph node measuring 2x1x0.5cm.cut surface:fatty infiltration.,a) multiple sections reveal tiny focus of ductal carcinoma in situ amidst foamy macrophages.there are also areas of hyalinization and scattered lymphoplasmacytic infiltrate.lymphovascular invasion and perineural invasion are not identified.the superior inferior medial lateral and deep margins are free of tumor.b) right axillary lymph nodes:total no. of lymph nodes isolated:14.total no. of lymph nodes involved:00.,a) right breast lump wide local excision:small focus of residual dcis measuring 0.4cm states post nact.lymphovascular invasion and perineural invasion are not identified.resected margins: superior margin free of tumor. inferior margin free of tumor. medial margin free of tumor. lateral margin free of tumor. deep margin free of tumor.b) right axillary lymph node:total no. of lymph nodes isolated:14.total no. of lymph nodes involved:00.
MRA165867,right breast carcinoma recurrence in axilla.,right axillary lymphatics,fibrofatty tissue measures 5x5x2cm. resected only few lymphnodes cells fibrotic areas and small cystic spaces are present. all the margins show fibrofatty tissue.,multiple sections shows three lymphnodes showing fibrotic areas with histocytes and hemosiderin pigment. cystic spaces with foamy macrophages are present. there is no evidence of tumor present. all the margins show fibrofatty tissue.,wide local occasion of right axilla:three fibrotic nodes with cystic areas are noted.no evidence of residual viable tumor present.
MRA166040,carcinoma breast.,endometrial lesion biopsy.,received multiple grey brown fibrofatty tissue measures 0.2x0.2x0.1cm. entire tissue processed.,section shows strips of stratified squamous epithelium with minimal subepithelial. no definite evidence of malignancy is seen.,endometrial lesion biopsy:shows only strips of squamous epithelium.no atypia is seen.
MRA166195,carcinoma right breast post ct.,right modified radical mastectomy.,received in : formalin fresh procedure : mr mastectomy.laterality : right. total dimensions : medial to lateral 15cm. superficial to deep 9cm. superior to inferior 4cm.skin ellipse : 12x7cm. nipple : normalscar surgical defect : not present.tumor : single multiple tumour size : location of tumor : nodular greywhite area seen in inner upper quadrant. margins of tumor : larger measuring 2.5x1.3x1cm.cut surface : greywhite. deep margin : 0.9cm.muscle : absent adjacent breast : fibrofatty tissue. axillary tail : 9x5x2cm.total number of nodes : 17 nodes.size of largest node : 1.4x1x0.9cm cut surface : greybrown.,sections reveal breast parenchyma harboring a neoplastic lesion arranged in tubules nests sheets consisting of oval to cuboidal cells demonstrating moderate atypia and eosinophilic cytoplasm.there are prominent areas of necrosis fibrosis therapy related changes and mixed inflmmatory infiltrate.,right breast right modified radical mastectomy: residual invasive carcinoma status post nact grade ii.modified br score is 6 9.tubule formation: 2.nuclear pleomorphism: 2.mitotic figures: 2.tumor measures 2.5cm in greatest dimension. ductal carcinoma in situ is present.lymphovascular invasion is identified.perineural invasion is not identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: 17 lymph nodes no metastatic deposits of tumor (0 17). summary: right mrm residual invasive carcinoma status post nact.lymph nodes: 17 lymph nodes no metastatic deposits of tumor (0 17).
MRA166197,carcinoma right breast post nact.,a) right breast wide excision.b) right axillary lymph node dissection.,a) received lumpectomy specimen measuring 9x6.5x3cm.skin ellipse measuring 6.5x3cm.on serial sectioning identified a greywhite area measuring 2x1.5x0.8cm.located at the following distances from respective margins: superior margin 0.7cm.inferior margin 3cm.medial margin 3cm.lateral margin 2cm.deep margin 1cm.muscle measures 3x2x0.8cm.b) received fibrofatty tissue measuring 9x7x3cm.largest lymph node measuring 2x1x0.8cm.cut surface shows fatty infiltration.,a) sections from tumor shows breast parenchyma infiltrated by a neoplasm arranged as tubules clusters and cords.the neoplastic cells exhibit moderate to marked nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm.lymphovascular emboli seen.b) 14 lymph nodes from right axillary lymph node dissection are free of tumor.,a) invasive ductal carcinoma right breast wide excisionmbr score is 7 9 grade 2.tumor size:2x1.5x0.8cm.tubule formation:3nuclear pleomorphism:2mitotic figures:2tumor size:2x1.5x0.8cm.all resected margins including deep are free of tumor.b) 14 lymph nodes from right axillary lymph node dissection are free of tumor.
MRA166388,known case of carcinoma right breastnow presented with right chest wall mass recurrence.,biopsy from right chest wall mass.,received multiple grey white to grey brown linear cores measures 0.8 to 1.2cm. entire tissue is processed.,linear cores from chest wall shows sheets of atypical cells with abundant cytoplasm and hyperchromatic nucle . foci of immature and mature osteoid formation lobules of cartilage are seen these cells are admixed with multinucleated giant cells and lymphoplasmacytic infiltrate. mitotic activity is discerned.,right chest wall mass known case of carcinoma breast.features are suggestive recurrence of disease in a treated case of metaplastic carcinoma.
MRA166676,known case of carcinoma right breast post breast conservative surgery,biopsy from right breast lump,received multiple grey white linear cores measures 0.8 to 1.0cm.entire tissue is processed,section shows linear cores of fibrocollagenous and adipose tissue harboring an infiltrating cellularlesion arranged in sheets. the cells are polygonal having moderate amount of cytoplasm hyperchromaticnucleus and prominent nucleoli. mitotic figures are discerned. stroma shows desmoplasia with areas ofhemorrhage and necrosis,right breast lump biopsy:recurrent invasive carcinoma nst grade ii status post breast conservative surgery and nacttubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9 areas of necrosis seen
MRA166940,carcinoma breast post op.liver space occupying lesion metastasis. hcc.,biopsy from liver,received 5 grey white linear cores measuring 1.3 to 1.6 cm.entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,liver core biopsy:positive for malignancy.suggestive of metastatic carcinoma in known and treated case of carcinoma breast.suggest ihc.
MRA167030,known case of left breast carcinoma.,right breast core biopsy.,received four grey white to grey brown linear core measures 1.2 to 1.4cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in cords and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6 (3+2+1).
MRA167108,known case of carcinoma breast post operative.,biopsy from right chest wall.,received 5 greywhite linear cores measuring 1.2 to 1.5cm. entire tissue processed.,linear cores of fibrous tissue infiltrated by a neoplasm arranged as cords and clusters. the neoplastic cells have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is scant. areas of necrosis seen.,invasive carcinoma biopsy from right chest wall.suggestive of recurrence metastasis in a known case of carcinoma breast.
MRA167216,lump in left breast.,biopsy from left breast lump.,received multiple grey white to grey brown linear cores measures 0.3 to 0.6cm. entire tissue is processed.,linear cores of tissue demonstrating cellular dyscohesive sheets of round to oval neoplastic cells harboring pleomorphic vesicular nuclei and abundant eosinophilic cytoplasm amidst areas of necrosis and hemorrhage. there are numerous multinucleated cells. mitotic activity is seen.,biopsy from left breast lump:poorly differentiated malignancy metastatic carcinoma from thyroid.suggest ihc
MRA167218,carcinoma breast.,biopsy from right breast.,received 5 grey white linear cores measures 1.2 to 1.3cm. entire tissue processed.,section shows cores of breast parenchyma with an infiltrating lesion arranged as sheets nests and cords. the lesional cells exhibit moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. stroma shows desmoplasia and lymphocytic infiltrate.,right breast biopsy :invasive ductal carcinoma grade ii.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MRA167314,carcinoma breast liver lesion metastases,biopsy from liver lesion.,received multiple tiny grey white linear cores measures1 to 1.2cm. entire tissue processed,linear cores of tissue demonstrating a neoplastic lesion arranged in tubules cords and nests consisting of round to oval cells exhibiting moderate nuclear pleomorphism and pale eosinophilic cytoplasm. there is brisk mitotic activity and areas of necrosis.,biopsy from liver lesion:the features are suggestive of metastatic deposits in a known case of carcinoma breast.
MRA167407,complaint of left locally advanced carcinoma breast.,a) breast wide local excision.b) left axillary lymph nodes.c) level iii lymph nodes.,a) received lumpectomy specimen measuring 13x11x4.5cm.skin ellipse measuring 11x6cm.cut surface shows grey white relatively well circumscribed lesion seen measuring 4.2x3.5x3cm.located at the following distances from the respective margins: superior margin 3.5cminferior margin 4cmmedial margin 4cmlateral margin 3cmdeep margin 1.5cm.b) received fibrofatty tissue measuring 8x5.5x1.5cm.largest lymph node measuring 2x1x0.5cm.cut surface shows grey white.dissected 12 nodes.c) level iii lymph nodes sow fibrofatty tissue measuring 2x1x0.3cm.dissected 2 nodes.,a) breast wide local excision : tumor bed invasive ductal carcinoma.viable tumor is present.surrounding the large necrotic areas are present morethan 50 grade : tubular formation : 3nuclear pleomorphism : 2 mitotic figures : 3 8 9 nuclear grade iii.lymphovascular invasion is present.perineural invasion is present.ductal carcinoma insitu is not seen.resected margins aresuperior margin free of tumor.inferior margin free of tumormedial margin free of tumor.lateral margin free of tumor.deep margin free of tumor.b) axillary lymph nodes:one node show metastatic deposits of tumor out of 12 nodes.perinodal spread is present.c) level iii lymph nodes:2 nodes no deposits of tumor.,a) breast wide local excision : invasive ductal carcinomaviable tumor is present.large areas of necrosis is present more than 50 ductal carcinoma insitu is not present.lymphovascular invasion is present.perineural invasion is present.all resected margins are free of tumor.b) axillary lymph nodes: one node show metastatic deposits of tumor out of 12 nodes.perinodal spread is present.size of the biggest node is 2x1cm.c) level iii lymph nodes:2 nodes no deposits of tumor.
MRA167501,right breast lump carcinoma breast.,biopsy from right breast lump.,received 4 linear cores measures 1.1.5cm. entire tissue processed.,section shows linear cores of tumor composed of nests and cords of round to oval cells with enlarged hyperchromatic nucleus and scant to moderate cytoplasm. nuclear pleomorphism is mild and mitosis are sparse.,right breast lump biopsy :invasive ductal carcinoma nst. grade ii. mbr score (3+1+1) 5 9
MRA167558,carcinoma right breast post nact.,a) right breast wle post nact.b) right side axillary node dissection.,a) fresh tissue received : yesnumber of specimens received : 1laterality : rightprocedure : lumpectomy post nact.specimen orientation : 6 o clock 1.0cm. 12 o clock 0.3cm 3 o clock 1.5cm 9 o clock 0.5cmspecimen size : 8x5x2.5cm skin : present skin dimensions : 7.5x3cm. skin abnormalities : absent.nipple : absentlesion(s) : presentnumber of macroscopically visible lesions : single.for each lesion (if gt 1 designate accordingly): lesion description :well circumscribed greywhite lobulated. lesion dimensions :3.2x3x3cm.b) multiple fibrofatty tissue altogether measuring 6.5x6.5x2cm.largest lymph node measuring 2x1x0.8cm.cut surface is fatty infiltration.,section shows breast parenchyma harboring a lesion arranged in sheets.the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli.stroma shows desmoplasia with inflammatory infiltrates areas of hemorrhage and necrosis are seen.atypical mitotic figures are discerned.no lymphovascular invasion seen.,a) right breast wide local excision post nact.residual invasive ductal carcinoma grade 3.mbr score is 8 9 (3+2+3).tumor measures 3.2cm in greatest dimension.lymphovascular invasion is not identified.perineural invasion is not identified.all margins of resection(12 o clock 6 o clock 3 o clock and 9 o clock) are free of tumor.nipple and areola is unremarkable.b) right side axillary node dissection:21 out of 21 lymph nodes are free of tumor(0 21).they show reactive hyperplasia.
MRA167689,known case of carcinoma right breast.,right breast lesion core biopsy.,received six grey white to grey yellow linear cores measure 0.3 0.5 cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in diffuse sheets amp nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. areas of necrosis are seen.,right breast lesion core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MRA168167,carcinoma left breast(post chemo).,left breast left modified radical mastectomy.,received in : formalinprocedure : mastectomy post nact laterality : left. total dimensions : medial lateral : 15cm superficial deep: 3cm superior inferior : 12cm.skin ellipse : 14x9cm. nipple : unremarkable.scar surgical defect : not seen.tumor : multiple(3)tumour size : 1) 2.5 x 2 x 2 cm. 2) 1.5 x 1.5 x 1 cm. 3) 3 x 1.5 x 1.5 cm distance to nearest separate tumor foci (when multiple ):1) to 2) distance is 3.5cm 1) to 3) distance is 1.1cm 3) to 2) distance is 3.5cm.location of tumor : upper outer and lower outer quadrant. minimum margin clearance from all tumor deposits (when multiple)specify which margin from which tumor eg nodule 1 nodule 2 etc)margins of tumor : infiltrative. muscle : absent adjacent breast : fibrofatty axillary tail : 5x5x1.5cm.total number of nodes : 20 (specify if sentinel nodes sent )size of largest node : 1.5x1x1cm.cut surface is greywhite.,section shows tumor cells in diffuse sheets nests and cords. few lying in pools of extracellular mucin. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular invasion is identified.,left breast left modified radical mastectomy(post chemo) : residual invasive ductal carcinoma grade 3 modified bloom richardson score is 8(3+3+2). multiple tumor foci are seen in the upper and lower outer quadrant of the breast. largest tumor foci measures 3 cm in greatest dimension. lymphovascular invasion is identified. perineural invasion is not identified. ductal carcinoma in situ of solid and cribriform pattern with intermediate nuclear grade is seen. nipple and areola is free of tumor. posterior resection margin is free of tumor.lymph nodes : fifteen out of eighteen lymph nodes show metastatic tumour deposits with extranodal extension(15 18). size of the largest tumour deposit measures 1.6 cm in greatest dimension.pathological stage : ypt2(m)n3asummary : left mrm invasive ductal carcinoma grade 3. nodal metastases 15 18.
MRA168231,carcinoma left breast (post nact).,left breast left modified radical mastectomy post nact.,received in : formalinprocedure : modified radical mastectomy post nact laterality : left total dimensions : medial to lateral : 14cm. superficial to deep : 5cm. superior to inferior : 13cm.skin ellipse : 12.5x10cm. nipple areala : ulcerated. ulceration measuring 6x5cm.scar surgical defect : not seen.tumor grey white necrotic lesion : single.tumour size : 5.5x5x4cm. location of tumor : central and inner quadrant. margins of tumor : illdefined. deep margin : 1cm.muscle : absent adjacent breast : fibrofatty tissue. axillary tail :7x6x3cm.size of largest node :4x3.6x3cm. cut surface necrotic grey white involved matted.,multiple sections from the lesion shows breast parenchyma harboring an infiltrating ill defined neoplastic lesion arranged in sheets and cords. the cells are ovoid having moderate amount of cytoplasm. vesicular pleomorphic nucleus with prominent nucleoli. brisk mitotic activity noted. stroma shows desmoplasia with chronic inflammatory infiltrates. areas of hemorrhage and necrosis seen. tumor seen infiltrating overlying nipple and areola leading to ulcer formation. lymphovascular noted.,left breast left modified radical mastectomy post nact: residual invasive ductal carcinoma grade 3.modified br score is 3+2+2 8 9.tubule formation: 3nuclear pleomorphism: 2 mitotic figures: 3tumor measures 5.5cm in greatest dimension and is located in the central and inner quadrant. ductal carcinoma in situ seen with comedonecrosis.lymphovascular invasion identified.perineural invasion not identified.posterior resection margin is unremarkable.nipple and areola is involved by tumor.lymph nodes: isolated eleven lymph nodes metastasis: two shows metastasis (2 11).largest tumor foci measures 2.2cmextra nodal extension present.summary :left mrm residual invasive ductal grade 3.nodal metastases 2 11 with ductal carcinoma in situ and comedonecrosis.
MRA168510,known case of carcinoma right breast post mrmright chest lesion malignancy.,right chest wall lesion biopsy.,receive very tiny grey white grey brown soft tissue bits altogether measures 0.2 x 0.1 x 0.1 cm. entire tissue processed,section shows fragments of fibrocollagenous tissue showing lymphoplasmacytic infiltrate. no atypical cells are seen.,right chest wall lesion biopsy:shows features of chronic non specific inflammation.no evidence of malignancy seen.
MRA168731,carcinoma left breast post nact.,a) wide local excision for frozen.b) axillary lymph nodes.,a) received skin covered fibrofatty tissue measures 6x5x3cm.skin ellipse measures 1.8x0.6cm.cut surface shows ill defined grey white lesion measures 1.5x1x0.8cm.distance from deep margin 1.3cm.located at the following distances from the respective margins superior margin 2.2cminferior margin 1.3cmlateral margin 0.8cmmedial margin 0.8cmdeep margin 1.3cm.b) received fibrofatty tissue measures 7x6x2cm.largest lymph node measures 3.3x2x1cm. cut surface shows fatty infiltration.dissected 15 nodes.,a) wide local excision fro frozen :tumor bed: the sections from the frozen shows fibrotic and necrotic areas. no viable tumor cells are seen. further sections from the remaining tissue shows small clumps of pleomorphic cells with hyperchromatic nucleus and eosinophilic cytoplasm. degenerated and necrotic areas are present.small focus shows viable tumor.invasive ductal carcinoma measures 0.5x0.5cm in further sections.resected margins superior margin free of tumor.inferior margin free of tumor.lateral margin free of tumor.medial margin free of tumor.deep margin free of tumor.b) axillary lymph nodes :15 nodes show no deposits of tumor.,a) wide local excision for frozen :frozen section there is no evidence of viable tumor.in remaining specimen shows small focus of invasive ductal carcinoma. lymphovascular invasion is not present.all resected margins are free of tumor.b) axillary lymph nodes :15 nodes show no deposits of tumor.
MRA168768,local skin recurrence nodules,skin nodule for biopsy,received single skin covered soft tissue bits measures 4x2x1.5cm skin ellipse measures 4x2cm multiple ill defined nodules largest measuring 0.3 cm noted . nearest inked margin is 1cm away from nodules,section demonstrates skin with underlying neoplastic lesion in the subcutis consisting of round to oval cells arranged in sheets and nests exhibiting moderate to marked nuclear pleomorphism and pale eosinophilic cytoplasm. there is brisk mitotic activity,tumor deposits suggestive of recurrence in a known case of carcinoma breast
MRA168848,carcinoma right breast.,a) right breast conservation surgeryb) right sentinel lymph nodes.c) righ axillary lymph nodes.d) revised deep margin.,a) received lumpectomy specimen measuring 3.5x3x1.5cm.skin ellipse measuring 2x0.8cm.on serial sectioning greywhite mass measuring 1.5x1.1x1cm.seen which is located at following distances from the respective margins: superior margin 1cm.inferior margin 0.7cm.medial margin 0.8cm.lateral margin 1cm.deep margin 0.3cm.b) received single fibrofatty tissue measuring 1.5x1x0.5cm.largest lymph node measuring 1x0.5x0.5cm.entire tissue is processed.c) received fibrofatty tissue measuring 16x6x2cm.size of largest lymph node measuring 2x1x1cm.cut surface is greywhite.d) received single fibrofatty tissue measuring 2x1x0.8cm.entire tissue is processed.,sections from tumor show breast parenchyma infiltrated by a neoplasm arranged as tubules and islands.the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm.no lymphovascular emboli seen.foci of calcification seen.areas of solid and cribriform intermediate to high grade ductal carcinoma in situ seen.sections from superior inferior medial lateral and deep margins are free of tumor.overlying skin are unremarkable.b) 2 lymph nodes isolated are negative for malignancy.c) section shows 5 lymph nodes which are negative for malignancy.d) section shows fragment of fibromuscular tissue which is unremarkable.,a) invasive ductal carcinoma right breast.mbr score is 7 9 grade 2.tubule formation:3nuclear pleomorphism:2mitotic figures:2tumor size:1.5x1.1x1cm.no lymphovascular emboli seen.superior inferior medial and lateral margins are free of tumor.overlying skin is unremarkable.b) 2 right sentinel lymph nodes isolated are negative for malignancy.c) 5 right axillary lymph nodes isolated are negative for malignancy.d) revised deep margin: negative for malignancy.
MRA168949,carcinoma right breast.,a) right breast right modified radical mastectomy.b) level iii right axillary lymph nodes.,a) received in : formalin. time of receipt at lab : 5:30pm procedure : mastectomy mrm. laterality : right.total dimensions : medial lateral : 22 cm. superficial deep : 7 cm. superior inferior : 18cm.skin ellipse : 20 x 9.5 cm.skin surface shows nodular swelling measuring 3.5 x 3.5 cm corresponding with the tumor underneath and 4 cm lateral to nipple areola complex.nipple :normalscar surgical defect : not seen.tumor : : single. tumour size : 4.5 x 4 x 4 cm.location of tumor : upper outer quadrant.margins of tumor : infiltrative. deep margin : 1 cm.muscle : present measuring 3.5 x 2 cm. adjacent breast : fibrofatty total number of nodes : 20 size of largest node : 2.5 x 1.5 x 1 cm cut surface is greywhite.axillary tail : 5 x 5 x 4 cm.b) received single fibrofatty tissue measuring 2 x 2 x 1 cm. entire tissue is processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular invasion is identified. perineural invasion is not identified.,a) right breast right modified radical mastectomy :invasive ductal carcinoma grade 3. modified bloom richardson score is 8(3+2+3) tumor is unifocal and is located in the upper outer quadrant. tumor measures 4.5cm in greatest dimension. lymphovascular invasion is identified. perineural invasion is not identified. ductal carcinoma in situ component is not identified. overlying skin is free of tumor. nipple and areola are free of tumor. posterior resection margin is free of tumor and is 1.0 cm away from the tumor.lymph nodes :three out of twenty lymph nodes show metastatic tumor deposits with extranodal extension(3 20). size of the largest tumor foci measures 1.0 cm in greatest dimension.pathological stage : pt2n1a
MRA168970,carcinoma breast.,right axillary mass excision biopsy.,received encapsulated cystic mass measuring 6.5x4.5x3.5cm. cut surface yielded yellowish fluid no solid area seen.,section show thick fibrous cystic wall with lymphoplasmacytic infiltrate. few fibroblast and congested dilated vessels.,right axillary mass excision biopsy :benign cystic lesion.no evidence of malignancy.
MRA169232,irregular discrete lymph nodal mass in the left supraclavicular region. known case of carcinoma left breast.,biopsy from left supraclavicular lymph node.,received five grey white linear cores measuring 1 to 1.5 cm.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left supraclavicular lymph node core biopsy : positive for malignancy. suggestive of metastatic ductal carcinoma in a known case of carcinoma left breast.
MRA169371,right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received 4 grey white linear cores measures 1 2cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in nests and cords. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. stroma shows desmoplasia. mitosis 1 2 10 hpf. necrosis. ductal carcinoma in situ. slid type seen.,biopsy from right breast lump:invasive ductal carcinoma grade 2modified bloom richardson score is 6 9( 3+2+1).ductal carcinoma in situ solid type intermediate nuclear grade.note: tumor tissue is scant to do ihc.suggest repeat biopsy.
MRA19141,left breast lump.,biopsy from left breast mass.,received multiple grey white linear cores measures 0.8 to 0.9cm. entire tissue processed.,section shows linear cores of tissue shows extensive areas of solid cribriform and comedonecrosis type of ducal carcinoma in situ with apocrine change. the cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm. stroma show fibrosis and lymphoplasmacytic infiltrate.,biopsy from left breast mass:extensive ductal carcinoma in situ with comedonecrosis.there is a small focus suggestive of invasion
MRA19400,known case of carcinoma breast post opnow right breast lump malignant.,biopsy from right breast.,received multiple grey white to grey brown linear cores measuring 1 to 1.3cm.entire tissue is processed.,section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged as sheets and cords of pleomorphic cells with hyperchromatic nuclei with moderate atypia and moderate cytoplasm.atypical mitosis discerned. extensive ductal carcinoma in situ noted. areas of necrosis present.,biopsy from right breast invasive ductal carcinoma grade ii with extensive ductal carcinoma in situ (solid type).mbr score is 7 9tubule formation 3nuclear pleomorphism 3 mitotic figures 1 7 9 lymphovascular invasion is not seen.
MRA24414,known case of left breast.right breast lump.,right breast biopsy.,received multiple linear cores measuring 0.8 to 1cm. entire tissue processed.,section shows cores of breast parenchyma harboring a lesion arranged in nests sheets and islands case of large polygonal cells with markedly pleomorphic round to oval dark nuclei prominent nucleoli and moderate amount of clear to pale eosinophilic cytoplasm. ductal carcinoma in situ present. comedonecrosis pattern. brisk mitosis and atypical mitotic figures discerned. extensive areas of necrosis noted.,right breast biopsy :invasive carcinoma with medullary like areas grade 3.areas of necrosis seen.
MRA31169,old case of right breast carcinoma.,left breast excision biopsy:,received single fibrofatty tissue measuring 5x4x3cm cut surface no gross lesion identified.small fibrotic area noted measuring 1 x 0.5 x 0.5cm.distance from margins:superior margin : 0.9cminferior margin :0.8cmmedial margin :1cmlateral margin :1.2cmdeep margin :1.1cm,multiple section show one clump of cells showing papillary processes with fibrovascular core lined with cuboidal epithelial cells. the cells are irregularly arranged with atypia of the nucleus is present with eosinophilic cytoplasm. no mitotic figures are present. the ducts are lined with outer myeoepithelial cells . some of the ducts shows fibrocystic change and sclerosing adenosis with surrounding lymphocytic infiltration.there is no evidence of invasive malignancy.,left breast excision biopsy:intraductal papillomaatypical ductal hyperplasiafibrocystic diseasenote: advised ihc markers .myoepitelial markers for confirmation of intraductal papilloma
MRA32135,right anterior chest wall lesion recurrence carcinoma breast post ct rt.,right chest wall lesion.,received 8 grey white linear cores measures 2.5 3cm. entire tissue processed.,section from the breast parenchyma shows a lesion arranged in sheets and nests. the cells are round to oval with hyperchromatic nuclei and moderate amount of cytoplasm. adjacent stroma shows lymphoplasmacytic infiltrates. mitotic figures are seen.,right chest wall lesion:suggestive of recurrent tumor deposit of invasive ductal carcinoma in known and treated case of carcinoma breast.
MRA32898,a) left breast lump possibility of carcinoma breast.,a) left breast biopsy.,a) received multiple grey white linear cores measures 0.5 to 0.8cm.entire tissue is processed.,sections from breast shows fibrocollagenous tissue with ducts lined by 2 layer of cells. the cellsare round to oval nuclei with scant to moderate cytoplasm and abluminal cells and have round to oval cells with abundant cytoplasm. no atypia seen.,a) left breast biopsy:shows benign breast tissue.negative for malignancy.
MRA37031,right breast lesion malignant,biopsy from right breast lesion.,received 6 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harbouring infiltrating lesion arranged in tubules and cords . the lesional cells are round to oval having hyperchromatic moderately pleomorphic nuclei and scant cytoplasm. intervening stroma shows desmoplasia. mitosis 3 4 10hpf.,biopsy from right breast lesion:invasive ductal carcinomamodified bloom richardson score 6 9 grade ii.tubule formation : 3nuclear pleomorphism: 2mitotic figures : 1 6 9
MRA40385,known case of carcinoma left breast.right breast lump possibility of carcinoma breast.,biopsy from right breast lump.,received multiple grey white to grey yellow linear cores measures 0.5 1.2cm.entire tissue is processed.,section shows linear cores of breast parenchyma harboring few small foci of an infiltrative lesionarranged as nests and sheets. the cells have round to oval hyperchromatic pleomorphic nucleus and moderate cytoplasm. ductal carcinoma in situ with comedonecrosis noted. stroma shows dense lymphomononuclear infiltrate. occasional mitosis noted.,biopsy from right breast:invasive carcinoma nst grade 2.mbr score 6 9tubule formation 3nuclear pleomorphism 2mitosis 1 6 9
MRA41318,right breast lump possibility o f carcinoma breast.,biopsy from lump core biopsy.,received grey white to grey brown linear cores measures 0.2 0.5cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests lying in pools of extracellular mucin. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,biopsy from lump core biopsy:invasive carcinoma with mucinous features grade 2. modified bloom richardson score is 6(3+2+1).
MRA41764,case of right breast lump.,biopsy from right breast.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,linear cores of breast tissue harboring neoplasm arranged as cords and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytopalsm. the intervening stroma is elastotic.,biopsy from right breast:invasive carcinoma with lobular features grade 2.modified bloom richardson score is 6 9.tubular formation 3.nuclear pleomorphism 2mitotic activity 1 6 9
MRA43094,carcinoma breast.,biopsy from right lung nodule.,received single grey brown linear cores measure 0.5cm in length. entire tissue processed.,section shows cores of lung parenchyma with occasional nests and a single three dimensional cluster round to oval hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm.,known case of carcinoma left breast biopsy right lung nodule:few aggregates of monomorphic round cells atypical.needs ihc to conclusively rule out malignancy.
MRA43561,known case of right breast post op now cervical nodes.,biopsy from left cervical node.,received 5 grey white linear cores measures 0.5 to 1cm. entire tissue processed.,sections studied from linear cores from cervical lymph nodes harbors tumor tissue replacing the lymphoid cells. the cells are pleomorphic with scant eosinophilic cytoplasm and hyperchromatic irregular nuclei. occasional cells show prominent eosinophilic nucleoli 3 4 atypical mitosis 10hpf seen adjacent normal lymphoid tissue with fibrosis seen.,left cervical node biopsy :suggestive of metastatic carcinoma in a known case of carcinoma breast.
MRA44875,known case of carcinoma left breast.,left infraclavicular mass biopsy.,received multiple linear cores measures 1 to 1.5cm. entire tissue processed.,section shows cores of fibrocollagenous tissue with a lesion arranged in sheets nests and cords. cells have pleomorphic hyperchromatic nuclei and moderate cytoplasm. interspersed stroma shows lymphocytic aggregation. atypical mitosis noted.,left intraclavicular mass biopsy:suggestive of recurrence in a known case of carcinoma breast.
MRA48475,known case of carcinoma breast.multiple liver lesion.,liver lesion core biopsy.,received multiple grey white linear core measures 1 to 1.5 cm. entire tissue processed.,section shows tumor cells in nests and tubules. individual cells have hyperchroamtic nuceli and moderate amount of eosinophilic cytoplasm.,liver lesion core biopsy :positive for malignancy.suggestive of metastatic carcinoma most possible from breast.
MRA49744,known case of carcinoma right breast breast mrm.,biopsy from left breast lesion,received 3 grey white linear cores measures 1cm. entire tissue processed.,section show linear cores harboring an infiltrative neoplasm arranged in cords and occasional tubules. the individual neoplastic cells exhibit increased n c ratio mild to moderate nuclear pleomorphism inconspicuous nucleoli and scanty cytoplasm. the intervening stroma shows presence of fibrocollagenous connective tissue infiltrated by lymphocytes.,biopsy from left breast lesion:invasive carcinoma breast nos grade 1modified bloom richardson score is 4 9(2+1+1).
MRA50928,known case of carcinoma left breast post bcs.now right breast lump carcinoma breast.,right breast core biopsy.,received multiple grey white linear cores measures 0.5 to 1cm. entire tissue processed.,section show cores of fibroadipose tissue harboring an invasive neoplasm in sheets and nests with moderate cytoplasm and hyperchromatic moderate to markedly pleomorphic nuclei. there is dense inflammatory cells infiltrate in the stroma.,right breast core biopsy:invasive carcinoma nst grade iii. modified bloom richardson score is 8(3+3+2).
MRA51808,right breast lump with nipple discharge.,biopsy from right breast.,received 4 grey white linear cores measuring 1 to 1.5cm. entire tissue processed.,the section shows linear cores of breast parenchyma showing dense sclerosis and exhibiting tumor cells infiltrating in clusters and cords. the tumor cells are round to ovoid with hyperchromatic nuclei and moderate to scant pale to vacuolated cytoplasm.,right breast biopsy :invasive carcinoma nst grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MRA53173,right breast mass.carcinoma breast with ductal carcinoma in situ component.,right breast core biopsy.,received multiple grey white to grey brown linear cores measuring 0.5 to 1.3cm. entire tissue processed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MRA53659,carcinoma breast in 2009.,biopsy from left iliac bone.,received 3 linear cores of bony tissue measures 0.6 to 0.5cm. entire tissue processed.,section examined shows multiple fragments of bony trabecular and fibrocollagenous tissue. the intertrabecular spaces show loose fibrous stroma with focal chronic inflammatory infiltrate.,biopsy from left iliac bone:no evidence of malignancy in section examined. representative.please report biopsy if clinically indicated.
MRA56621,carcinoma right breast.,biopsy from right breast lump.,received multiple linear cores measures 0.5 to 1cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in sheets nests and cords. the cells are oval have pleomorphic hyperchromatic nuclei inconspicuous nucleoli and abundant eosinophilic cytoplasm. stroma shows desmoplasia and extensive lymphocytic infiltrate amounting to follicle formation mitotic activity is discerned.,right breast biopsy :invasive ductal cell carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........
MRA63101,carcinoma endometrium carcinoma breast pre paravertebral lesion deposit.,biopsy from paravertebral lesion.,received 7 linear cores measuring 0.9 to 1.2cm. entire tissue processed.,section shows multiple linear cores of tissue harboring a neoplastic lesion arranged in cords and trabeculae. the cells have spindle shaped hyperchromatic nuclei and scant cytoplasm. mitoses are seen. areas of hyalinisation and haemorrhage seen.,paravertebral lesion biopsy:favors metastatic deposit.suggest ihc.
MRA66714,carcinoma left breast,left breast wide excision post bcs+rt,received wide excision left breast measures 5x2.5x2.3cmon serial section no obvious tumor is identified fibrotic areas measures 0.6x0.5x0.5cm.distance from margins:superior margin : 0.4cmmedial margin : 1cminferior margin : 0.4cmlateral margin :1cmdeep margin : 0.6cm,section studied show breast parenchyma with a small focus showing ductal carcinoma in situ solid and cribriform pattern. the cells are ovoid having moderate amount of cytoplasm and hyperchromatic nucleus. stroma shows areas of hyalinisation and fibrosis. a single duct shows intraductal papilloma.,left breast wide excision post bcs+rt:ductal carcinoma in situ solid and cribriform with one duct showing intraductal papillomano invasion is identifiedductal carcinoma in situ measures 0.5cm in largest dimension.all margins ( superior inferior medial lateral and deep) are free of tumor
MRA67087,right breast mass carcinoma.,biopsy from right breast mass.,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by neoplastic cells arranged in abortive tubules cords and nests. the cells have round hyperchromatic nuclei and moderate eosinophilic cytoplasm.,biopsy from right breast mass:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
MRA69728,left breast lump carcinoma breast,biopsy from left breast.,received 5 grey white linear cores measures 1 to 1.5cm. entire tissue processed,section sow cores of breast parenchyma with lesion arranged in nests sheets and cords of cells in a background of mucin. cells have round to oval hyperchromatic nuclei and moderate amount of cytoplasm. adjacent stroma shows desmoplasia.,biopsy from left breast:suggestive of invasive carcinoma (cellular mucinous varant)
MRA73245,known case of carcinoma breast.liver sol metastasis.,liver sol core biopsy.,received 4 grey white to grey brown linear cores measuring 1 to 1.2cm.entire tissue processed.,section shows linear cores of hepatic parenchyma with features of steatosis and harboring a lesion arranged in tubules and cords. individual cells are moderately pleomorphic with round to oval hyperchromatic nuclei and moderate amount of cytoplasm.,positive for malignancysuggestive of metastatic carcinoma in known case of carcinoma breast biopsy liver .
MRA73515,post left mastectomy. right birads 4c.,biopsy from right breast.,received 5 grey white linear cores measures 0.5 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged in island and nests. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. areas of necrosis seen.,biopsy from right breast.infiltrating ductal carcinoma.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
MRA73807,left breast mass.,left breast mass trucut biopsy.,received 4 grey white to grey brown linear cores 0.5 to 1cm. entire tissue processed.,section shows fragments of tissue harboring lesion arranged in cribriform nests and cords comprising of round to oval cells with pleomorphic hyperchromatic nuclei and moderate cytoplasm. mucin present in spaces and extracellular. ares of hemorrhage and necrosis noted.,left breast mass trucut biopsy:mucinous carcinoma.
MRA73853,carcinoma left breast,biopsy from chest wall,received multiple grey white linear cores measures 1 to 1.5cm. entire tissue is processed,linear cores of fibrocollagenous tissue infiltrated by neoplastic glands and nests lined by cuboidal cells exhibiting moderate atypia and eosinophilic cytoplasm. mitotic figures are discerned. muscle bundles are also noted.,biopsy from chest wall lesion:metastatic carcinoma in known case of carcinoma breast
MRA74111,left lung mass neoplastic metastatic.,biopsy from left lung mass.,received 8 grey white to grey brown linear cores measures 0.8 to 1.5cm. entire tissue processed.,sections studied show cores of a lesion arranged as sheets and nests. the cells have moderate pleomorphic hyperchromatic nuclei and moderate cytoplasm. few cells with peripherally pushed dark nuclei and vacuolated cytoplasm noted. frequent mitotic figures noted.,left lung mass biopsy :poorly differentiated malignancy favor metastatic deposits in known case of carcinoma breast.
MRA74441,left breast lump carcinoma.,biopsy from left breast.,received 4 greybrown linear cores measuring 0.8 to 1cm. entire tissue processed.,section shows cores of breast tissue showing diffuse infiltration of plasma cells few of them show plasmablast like morphology. many binucleate cells also noted.,left breast core biopsy(known case of multiple myeloma post treatment) :suggestive of plasma cell neoplasm with plasmablastic morphology.please correlate with clinical and biochemical findings.
MRA75167,a) left pelvic sentinel lymph node.b) right pelvic sentinel lymph node.c) tah with bso specimen.d) left pelvic lymph node dissection.e) right pelvic lymph node dissection.,a) received fibrofatty tissue measuring 1.5x1x0.3cm. single tiny lymph node identified measuring 0.3x0.2x0.1cm.entire tissue processed.b) received fibrofatty tissue measuring 3x2x1cm.isolated 2 lymph nodes.largest measuring 0.6x0.5x0.4cm.c) tah with bso,procedure : tah+ bsouterus dimensions: midline fundal serosa to ectocervix : 6cm.maximum intercornual : 4.5cm.maximum anterior to posterior : 4cm.cervix dimentions : 1.5x1.8cm. unremarkable.cervix shape : normal.right ovary : 1.5x1x1cm. cut surface is unremarkable.left ovary : 1.5x1.3x1cm. cut surface is unremarkable.right fallopian tube : 5cm. unremarkable.left fallopian tube : 4.5cm.unremarkable.right parametrium : 3.8x1.8x0.2cm.left parametrium : 3x2x0.2cm.tumor dimensions : 2x2x0.8cm.involvement of myometrium by tumor : lt 50 leiomyoma : nolower uterine segment : unremarkable.other abnormalities : absent.d) received fibrofatty tissue measuring 3x2.5x1cm. entire tissue processed.e) received fibrofatty tissue measuring 4x2.5x1cm.largest lymph node measuring 2x1x0.5cm. cut surface shows greywhite. entire tissue processed.,section from endometrium shows a polyp shows dilated glands lined by single layer of cuboidal to columnar epithelium with focal areas showing glands with papillary configuration lined by pleomorphic cells with round to oval vesicular nuclei few with prominent nucleoli and moderate eosinophilic cytoplasm. small detached tumor buds are noted in the lumen along with hobbnail cells. apoptotic bodies are seen. stromal hypercellularity noted with focal stromal edema. adjacent endometrium shows atrophic glands.lower uterine segment : unremarkable no evidence of malignancy in the material submitted.cervix : few dilated endocervical glands are noted. nabothian cysts identified no evidence of malignancy in the material submitted.,c) uterus with bilateral ovaries and fallopian tubes total abdominal hysterectomy with bilateral salpingo oophorectomy:endometrium: adenocarcinoma. tumor measures 2cm in greatest dimension. tumor invades lt 50 of myometrium. lower uterine segment : free of tumor. cervix : free of tumor. right and left ovaries and fallopian tubes : unremarkable. right and left parametrium : unremarkable.a) left pelvic sentinel lymph node: one lymph node isolated free of tumor (0 1).b) right pelvic sentinel lymph node:seven lymph nodes isolated free of tumor (0 7).d) left pelvic lymph node dissection:one lymph node isolated free of tumor (0 1).e) right pelvic lymph node dissection:four lymph nodes isolated free of tumor (0 4).
MRA75870,known case of carcinoma breast .right iliac bone lytic lesion,biopsy from right iliac bone lesion.,received multiple grey white linear cores measuring 0.3 to 0.5cm. entire tissue processed.,linear cores of fibromuscular tissue demonstrating islands and nests of cuboidal to ovoid cells arranged in glandular papillary like and large tubular configuration exhibiting mild to moderate atypia and eosinophilic cytoplasm. there is a rich vascular network with aggregates of hemosiderin laden macrophages and lymphocytes.,biopsy from right iliac bone lesion :metastatic poorly differentiated malignancy metastatic carcinoma breastcould we please have the details of the primary histopathology report.
MRA76849,h o carcinoma breast 2010 post ctrt now with suspicious uptake in post cricoid region.,post cricoid region.,received multiple grey white soft tissue bits altogether measures 0.6x0.5x0.3 cm entire tissue processed.,section shows fragments of a neoplasm arranged as islands and nests. the neoplastic cells are polypoidal have vesicualr nuclei conspicuous nucleoli and moderate cytoplasm. keratin pearl formation seen.,well differentiated squamous cell carcinoma biopsy post cricoid region.
MRA81047,a) right axillary sentinel lymph node.b) right breast conservative specimen.c) revised deep margin.,a) received 3 blue nodes largest measures 0.6x0.4x0.3cm. cut surface shows dye stained.received 1 enlarged lymph node measures 1x0.8x0.5cm. cut surface shows fatty infiltrate.b) received breast conservative surgery specimen measures 4x3.5x2.2cm.skin ellipse measures 1.8x0.5cm.cut surface shows nodular greywhite mass measures 1.5x1.5x1.2cm.distance of tumor from margins: superior margin : 0.5cm.inferior margin : 0.6cm.medial margin : 1.2cm.lateral margin : 1.3cm.deep margin : 0.2cm.c) received fibrofatty tissue measures 2.5x1x0.5cm. one surface inked.,section studied shows fibroadipose tissue harboring an invasive lesion arranged in lobules separated by fibrous septae. the lobules shows loss of abluminal myoepithelial cells and luminal cells which are having moderate amount of eosinophilic cytoplasm pleomorphic vesicular nucleus with prominent nucleolus. brisk mitotic activity noted.,b) right breast conservative,invasive ductal carcinoma grade iiitumor size:1.5x1.5x1.2cmmbr score 8 9tubule formation : 3nuclear pleomorphism : 3mitotic activity : 2 8 9 dcis is not seen.lymphovascular invasion is not seen.perineural is not identified.all margins of resection are free of tumor.a) right axillary sentinel lymph node:four lymph nodes isolated all are negative for malignancy (0 4).c) revised deep margin: free of tumor.
MRA81082,carcinoma breast post op.,biopsy from cervix biopsy.,received multiple grey white to grey brown soft tissue bits altogether 1.5x1x0.5cm.entire tissue processed.,fragments of cervical mucosa exhibiting full thickness dysplasia amounting to cervical intraepithelial neoplasia (ciniii) . a few dysplastic islands with evidence of keratin pearl formation are seen invading subjacent stroma.,well differentiated squamous cell carcinoma biopsy from cervix.
MRA81210,carcinoma endometrium in a p.o carcinoma left breast in 2011,a) uterus cervix with bilateral adnexa hysterectomy with bilateral salpingo oophorectomy.b) right pelvic lymph node clearance.c) left pelvic lymph node clearance.,a) fresh tissue received : yes. procedure : extrafascial hysterectomy with bilateral salpingo oophorectomy. uterus dimensions: midline fundal serosa to ectocervix : 9 cmmaximum intercornual : 5.5cmmaximum anterior to posterior : 2.5cmcervix dimensions : 2x2cm ( anterior posterior x transverse) ulceration noted in post lip.vaginal cuff : absent.right ovary : present 2x1x0.5cm cut surface:unremarkable.left ovary : present 2.5x1.3x0.5cm cut surface:unremarkable.right fallopian tube : present 4.5cm cut surface:unremarkable.left fallopian tube : present 5 cm cut surface:unremarkable.right parametrium : 2x0.5x0.5 cmleft parametrium : 2x1x0.5 cmendometrium description : endometrium shows greywhite friable polypoidal lesion measuring 3x1.5x1cm.myometrium description:involvement of myometrium by tumor : less than 50 lower uterine segment : well circumscribed lesion in myometrium measuring 0.2cm in diameter fibroid.representative sections are submitted.b) received fibrofatty tissue measuring 4x3x1.5cm largest lymph node measuring 2.5x1x0.5cm.cut surface : fatty greybrown infiltration.c) received fibrofatty tissue measuring 3.5x2.5x1cm largest lymph node measuring 2.7x1x0.5cm.cut surface: greybrown.,section shows tumor cells in confluent glandular pattern. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular invasion is not identified.,a) uterus cervix with bilateral adnexa hysterectomy with bilateral salpingo oophorectomy :endometrium :endometrioid adenocarcinoma figo grade 1. tumor measures 3 cm in greatest dimension. tumor invades less than half ( lt 50 ) of the myometrial thickness. lymphovascular invasion is not identified. lower uterine segment is free of tumor. myometrium shows leiomyoma.cervix :negative for malignancy.right and left parametria :negative for malignancy.right and left ovaries and fallopian tubes :negative for malignancy.b) right pelvic lymph node clearance :ten lymph nodes are identified negative for malignancy(0 10).c) left pelvic lymph node clearance :three lymph nodes are identified negative for malignancy(0 3).pathological stage : pt1an0
MRA81549,carcinoma breast.,biopsy from left breast mass.,received multiple grey white to grey yellow linear cores measures 0.3 to 1cm. entire tissue processed.,section shows cores of breast parenchyma with an infiltrative lesion arranged in cords nests and in sheets cells show moderate nuclear pleomorphism hyperchromatic nuclei and moderate eosinophilic cytoplasm. mitotic figures discerned. areas of necrosis and hemorrhage seen.,biopsy from left breast mass:infiltrating carcinoma nst grade iii.modified bloom richardson score 8 9.tubular formation 3nuclear pleomorphic 2mitotic figures 3 8 9 areas of necrosis seen.
MRA81704,left breast lesion.,left breast lesion biopsy.,received multiple grey white linear cores measures 1.5 to 1.8cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue infiltrated by neoplastic cells arranged in sheets and cords. the cells have round hyperchromatic nucleus and moderate cytoplasm. surrounding stroma shows desmoplasia.,left breast lesion biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
MRA82127,left breast lump birads 4 lesion.,biopsy from left breast lump.,received 5 grey white to grey brown slender linear cores measures 0.6 0.8cm. entire tissue processed..,the section shows fragments of tissue consisting pleomorphic ductal cells with hyperchromatic nucleus and eosinophilic cytoplasm. intra luminal micin and extracellular mucin is present. mbr score is 6 9. nottingham grade ii,biopsy from left breast lump:mucinous carcinoma nuclear grade ii.
MRA82262,carcinoma right breast post lumpectomy cystic lesion at incision site recurrence,biopsy from cystic lesion.,received 4 grey white to grey brown linear cores measuring 0.4 to 0.5cm.entire tissue processed.,linear fragmented cores of fibrous tissue seen.,no evidence of malignancy at biopsy from cystic lesion at incision site .
MRA83056,multiple lung nodule metastasis.,biopsy from right lung nodule.,received 6 grey white to linear core measures 1 to 1.5cm. entire tissue processed.,the sections show linear cores of densely sclerotic tissue showing tumor cells infiltrating in nests and cords. the tumor cells are round to ovoid with enlarged pleomorphic hyperchromatic nuclei and moderate to scant pale eosinophilic cytoplasm. large areas of necrosis are seen.,biopsy from right lung nodule :poorly differentiated carcinoma metastatic in known case of carcinoma breast. suggest ihc.
MRA83708,case of carcinoma right breast,biopsy from liver lesion,received 10 grey white white linear cores measures 1.5 2.2cm. entire tissue processed.,linear cores of liver tissue infiltrating by a neoplasm arranged as cords and clusters. the neoplastic cells have hyperchromatic nuclei and have moderate cytoplasm. the intervening stroma is fibrotic,biopsy from liver lesion :metastatic carcinoma of ductal origin.
MRA83843,left infraclavicular lesion,biopsy from left infraclavicular lesion,received multiple grey white linear cores measures 1 to 1.2cm. entire tissue processed.,linear cores of tissue infiltrated by sheets cords nests of round to oval neoplastic cells exhibiting moderate nuclear pleomorphism and eosinophilic cytoplasm amidst a desmoplastic stroma.,biopsy from left infraclavicular lesion:invasive carcinoma metastasis from breast. local recurrence.please correlate with clinical findings.
MRA86273,carcinoma breast multiple liver lesion.,biopsy from liver.,received 7 grey white linear cores measuring 1 to 1.5 cm. entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in nests cords and abortive glands. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,liver core biopsy:positive for malignancy.suggestive of metastatic carcinoma most possible from breast.
MRA88105,previously treated carcinoma breast with left supraclavicular lymph node,left supraclavicular lymph node.,received single lymph node measures 1x0.8x0.6cm. entire tissue processed.cut surface grey white to grey brown.,section from supraclavicular lymph node shows effaced architecture with rim of mature lymphocytes. the atypical cells are arranged in clusters show round nucleus. conspicuous nucleoli and eosinophilic cytoplasm. extracellular mucin seen.,metastatic carcinoma in a known case of carcinoma breast.
MRA88880,known case of carcinoma breast with multiple liver lesions metastasis.,liver lesion biopsy,received multiple grey white linear cores measures 0.8 to 1 cm. entire tissue processed.,section show linear cores of liver tissue with an infiltrating lesion arranged in nests sheets. the cells have moderately pleomorphic hyperchromatic nuclei and moderate amount of cytoplasm. stroma show desmoplasia and areas of necrosis seen. mitotic figures are 2 3 10 hpf.,liver lesion biopsy:metastatic carcinoma in a known case of carcinoma breast .report on er pr to follow.
MRA89461,right breast lump carcinoma breast.,biopsy from right breast lump.,received grey white linear core measures 0.5 to 1cm. entire tissue processed.,section shows cores of breast tissue with composed elongated ducts lined by epithelial and myoepithelial cells few showing ductal hyperplasia. stroma is cellular composed of spindle cells and a myxoid background. mitosis is occasional.,biopsy from right breast lump:fibroepithelial neoplasm.possibility of cellular fibroadenoma is considered.suggest biopsy.
MRA90733,carcinoma right breast post operative.right chest wall lesion deposit.,biopsy from right chest wall lesion.,received multiple grey white linear cores measures 1.8 to 2 cm. entire tissue is processed.,linear cores of tissue infiltrated by nests cords tubules of round to oval neoplastic cells exhibiting moderate nuclear pleomorphism and eosinophilic cytoplasm with brisk mitotic activity amidst a desmoplastic stroma.,biopsy from right chest wall lesion:recurrent carcinoma (high grade) metastases in a known case of carcinoma breast.please correlate with clinical findings .
MRA91358,carcinoma breast post mrm,cervix biopsy.,received 2 grey white soft tissue bits measures 1 x 0.8 x 0.3 cm. entire tissue processed.,section shows ectocervix lined by stratified squamous epithelium. no loss of polarity is seen. stroma shows fibrocollagenous tissue with lymphocytes and congest capillaries. no atypia is seen. focal ulceration is also seen.,cervix biopsy:features are suggestive of chronic non specific inflammation with focal ulceration.
MRA918,carcinoma right breast post op ct rt with left cervical lymph nodes.,left cervical lymph node excision biopsy.,received two lymph nodes largest measuring 1x0.5x0.5cm. cut surface grey white other lymph node 0.8x0.5x0.5cm. cut surface fatty infiltration.,section from lymph nodes shows metastatic tumor deposit from breast.,left cervical lymph node excision biopsy :two lymph nodes identified both shows metastatic tumor deposits from breast with extranodal extension (2 2). size of the larger tumor deposit measures 0.8 cm in greatest dimension.
MRA92213,left lump mass in a known case of carcinoma breast post mrm,biopsy from left lump mass.,received multiple grey white fragmented linear cores measures 0.2 0.5cm. entire tissue processed.,section shows fragmented tissue bits showing fibrofatty connective tissue with abundant intracellular mucin. few bits show neoplastic cells arranged in nests exhibiting increased n c ratio pleomorphic hyperchromatic nuclei and occasional conspicuous nucleoli and scant to moderate amount of pale eosinophilic cytoplasm.,biopsy from left lump mass:mucinous carcinoma. primary metastatic.
MRA93981,left breast lump carcinoma breast.,biopsy from left breast lesion,received 5 grey white linear cores measures 0.3 0.8cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring foci of ductal carcinoma in situ comedo pattern. an occasional focus suspicuous of invasion seen.,biopsy from left breast lesion:high grade ductal carcinoma in situ ( comedo pattern).definite invasive focus needs to be ascertained on larger tissue.
MRA94192,known case of carcinoma left breast.,biopsy from left chest wall.,received 3 greywhite to greybrown linea cores measuring 0.5 to 1.2cm. entire tissue processed.,section shows linear cores of tissue fragments harboring a neoplastic lesion arranged in vague tubular formation nests sheets and trabeculae. the cells are highly pleomorphic with round to ova vesicular nuclei prominent nucleoli and scant cytoplasm. areas of fibrosis noted.,metastatic carcinoma biopsy from left chest wall in a known case of carcinoma breast.
MRA94198,left axillary node metastatic.,left axillary node.,received 3 tiny grey white linear cores measures 0.2 to 0.5cm. entire tissue processed.,section shows linear cores of fibrofatty tissue infiltrated by neoplastic cells arranged in lobules and nest. individual cells have hyperchromatic nuclei inconspicuous nucleoli and moderate amount of cytoplasm.,left axillary node core biopsy :suggestive of metastatic carcinoma in a known case of carcinoma breast.
MRA95266,left breast mass carcinoma breast.,biopsy from left breast.,received 3 grey white linear cores measures 1.5 2cm. entire tissue processed.,section studied show fibrous tissue with extensive areas of hyalinisation and an infiltrating lesion arranged in nests and vague tubules. the cells are ovoid having moderate amount of cytoplasm and hyperchromatic nucleus. stroma is desmoplastic edematous with areas of hemorrhage. mitotic figures are discerned.,biopsy from left breast:invasive carcinoma nst grade 3.modified bloom richardson son score is 7(3+2+2).
MRA96527,carcinoma breast with multiple bone metastasis,biopsy from left ilium,received multiple grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue is processed.,section shows cores of tissue infiltrated by tumor cells in nests diffuse sheets and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left ilium biopsy(known case of carcinoma breast):positive for malignancysuggestive of metastatic carcinoma in known case of carcinoma breast.
MRA96751,known case of carcinoma breast treated 6 yrs back on follow up no with complex ovarian cyst.,left and right ovaries.,received two ovaries larger left ovary is cystic that measures 5x5x3.3cm and weighs 50gm. fallopian tube is absent.external surface capsule intact cut surface shows multiloculated cysts filled with chocolate brown creamy material. no solid areas seen.right ovary measures 3.5x2x1.5cmfallopian tube measures 5.5cmcut surface cystic spacesno solid areas seen.,section from left ovary shows ovarian parenchyma consisting of spindle cells with thick hyalinised blood vessels with sheets of foamy macrophages and hemosiderin laden macrophages. cysts are lined by flattened epithelial cells. no atypia malignancy is noted in the material submitted.section from right ovary shows ovarian parenchyma with corpus albicanti and thick walled blood vessels. focal cystically dilated spaces lined by flattened epihtelium is seen. no atypical malignancy is noted in material submitted.,left and right ovaries:hemorrhagic benign cysts and corpus albicantino evidence if malignancy in the material submitted.left and right fallopian tubes unremarkable.
MRA96934,known case of carcinoma breast with pmb.,endometrial biopsy.,received 2 grey to grey brown soft tissue bits measures 0.2 x 0.2x0.1cm. entire tissue processed.,section shows fragments of endometrial tissue harboring a few tubular endometrial glands lined by cuboidal cell. these cells exhibit moderate cytoplasm. the stroma is compact.,endometrial biopsy. scant volume of endometrial tissue with non secretory glands.note:kindly correlate with clinical and imageological findings and suggest follow up.
MRA97865,known case of carcinoma breast.right neck nodes p o deposit.,biopsy from right neck node.,received multiple grey white linear core measures 0.3 to 1cm. entire tissue processed.,section shows linear cores of lymphoid tissue with epitheloid cell clusters transforming histiocytes multinucleated giant cells and immunoblasts. areas of hemorrhage and necrosis are noted.,biopsy from right neck node:granulomatous inflammation of probable koch s etiology.
MRA98425,carcinoma breast.,endometrial tissue and polyp biopsy.,received grey white to grey brown soft tissue bits measures 3.5x2x1.5cm. entire tissue processed.,sections show multiple fragments of endometrial tissue with a polypoidal lesion having cytstically dilated glands lined by low columnar epithelium. surrounding stroma shows infiltration by lymphocytes and plasma cells. areas of hemorrhage seen. no atypical cells malignancy seen in the sections studied.,endometrial tissue and polyp biopsy :features are suggestive of inflammatory polyp.
MRA99802,carcinoma breast.omental lesion deposit.,biopsy from omental lesion.,received 4 greywhite greywhite to greybrown linear cores measuring 0.3 to 0.5cm.entire tissue is processed.,fragmented linear cores of fibrofatty and fibromuscular tissue exhibiting small nests and islands of ovoid cells harboring dark staining nuclei and moderate amount of eosinophilic cytoplasm.there are foci of hemorrhage and scattered lymphoplasmacytic infiltrate.,biopsy from omental lesion:metastatic carcinoma adenocarcinoma .please provide clinical amp radiologic findingssuggest ihc.
MRA99996,case of carcinoma thyroid and carcinoma right breast post treatment.,biopsy from left level v cervical lymph node.,received 3 lymph nodes fibrofatty tissue largest measuring 1x0.7x0.3cm.cut surface grey white.entire tissue processed.,section show lymph nodes infiltrated by a neoplasm arranged as islands and sheets and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. no perinodal spread seen.,metastatic carcinomatous deposit biopsy from left level v cervical lymph node. breastneeds further work up.
TM16000933,right breast mass. carcinoma breast (birads iv).,biopsy from right breast.,received 4 grey white to grey brown linear cores measuring 0.5 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring a lesion arranged in sheets. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli in few cells. stroma shows desmoplasia with dense inflammatory infiltrate. atypical mitotic figures are discerned. areas of hemorrhage and necrosis seen.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
TM16002036,left breast lump carcinoma.,biopsy from left breast.,received 3 grey white to grey brown linear cores measuring 0.7 to 1.2cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arrranged as tubules cords and islands. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,infiltrating ductal carcinoma biopsy from left breast.modified br score is 6 9 grade 2tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
TM16002681,right breast lump carcinoma.,right breast biopsy.,received 4 grey white to grey brown linear cores measuring 0.7 to 1cm.entire tissue processed.,linear cores from breast tissue shows a neoplastic lesion arranged in trabeculae and tubular pattern. the tumor cells have hyperchromatic nuclei and moderate cytoplasm. mitotic figures are discerned. the intervening stroma is elastotic.,infiltrating ductal carcinoma right breast biopsy.modified br score is 6 9 grade 2.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
TM16002704,carcinoma left breast with skin infiltration.,left breast biopsy.,received skin covered soft tissue bits measuring 0.8 to 0.8 x 0.7 cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast biopsy :invasive ductal carcinoma grade 3. modified br score is 8(3+3+2). tumor is reaching upto the skin. perineural invasion is identified. lymphovascular invasion is indeterminate.
TM16002774,known case of carcinoma breast. multiple liver space occupying lesion metastatic.,biopsy from liver.,5 grey white to grey brown linear cores measuring 1 to 1.5cm. entire tissue processed.,section shows linear cores of liver tissue harboring a neoplasm arranged in tubules trabeculae and nests. neoplastic cells exhibit moderately pleomorphic nuclei with moderate to abundant cytoplasm. the intervening stroma is scant.,biopsy from liver :metastatic carcinoma in a known case of carcinoma breast .
TM16002798,right breast lump carcinoma.,biopsy from right breast.,received five grey white to grey brown linear cores measuring 0.5 to 1.2cm.entire tissue processed.,linear cores of breast parenchyma showing neoplasm arranged as islands and nests. the neoplastic cells have hyperchromatic nuclei exhibiting moderate nuclear pleomorphism and moderate cytoplasm. mitotic figures are discerned. afew of the islands have central fibrovascular cores.,invasive carcinoma biopsy from right breast.modified br score is 8 9 grade 3.tubule formation : 3nuclear pleomorphism :2mitotic figures : 3 8 9
TM16003502,not provided.,biopsy from right breast.,received 4 grey white to grey yellow linear cores measuring 0.8 to 1.2cm.entire tissue processed.,linear cores of breast parenchyma infiltrated by a neoplasm arranged as clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is fibrous .lymphovascuar emboli seen.,infiltrating ductal carcinoma biopsy from right breast.modified br score is 7 9 grade 2.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2. 7 9
TM16004140,carcinoma left breast.,biopsy from left breast.,received 3 grey white linear cores measuring 1.2 to 1.5 cm. entire tissue is processesed.,section shows cores of breast parenchyma harboring a neoplastic lesion infiltrating the stroma. cells are arranged in nests tubules and in sheets exhibiting moderate nuclear pleomorphism hyperchromatic nuclei and moderate cytoplasm. mitotic figures discerned.,biopsy from left breast :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
TM16004342,hypoechoic area in left breast mastitis benign breast disease,biopsy from left breast,received 3 grey white to grey brown linear cores measuring 1 to 1.2 cm.entire tissue processed.,linear trucut cores of fibrocollagenous tissue infiltrated by pleomorphic cells arranged in cords and singly scattered cells. cells have high n:c ratio hyperchromatic nuclei and inconspicuous nucleoli. some of the cells show eccentric nuclei with vacuolated cytoplasm. mitotic figures are discerned. stroma shows extensive desmoplasia.,left breastsuggestive of invasive carcinoma with lobular features grade 2.tubular formation 3nuclear pleomorphism 3mitotic figures 1 7 9
TM16004380,lump in left breast carcinoma breast. fibroadenoma,biopsy from left breast lump.,received multiple grey white linear cores measures 1 to 1.2cm.,linear cores of tissue demonstrating paucicellular and cellular diffuse proliferation of spindle cells with elongated nuclei and moderate amount of eosinophilic cytoplasm. there are interspersed vascular channels.,biopsy from left breast lump:the features are suggestive of benign spindle cell proliferationpossibilities considered are: 1) phyllodes tumor2) fibromatosisplease correlate with radiologic findings.needs confirmation on excised specimen
TM16005145,left breast lump carcinoma breast dcis.,biopsy from left breast lump.,received 5 greywhite to grey brown linear cores measuring 0.8 to 1.2cm. entire tissue processed.,sections from the specimen submitted as linear core biopsy from left breast lump shows breast parenchyma with predominant areas of dcis with comedonecrosis and foci of lobular cancerization. there are suspicious foci showing small aggregates and nodules of neoplastic cells infiltrating the stroma. the neoplastic cells have vesicular nuclei with small prominent nucleoli.,extensive dcis with comedonecrosis and small suspicious focus of invasion.suggest ihc for confirmation
TM16005264,right breast lump carcinoma,biopsy from right breast lump.,received 5 grey white linear cores measuring 1 to 1.2 cm.entire tissue processed.,section shows cores of tissue infiltrated by tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
TM16006031,carcinoma left breast post op left chest wall lesion.,biopsy from left chest wall mass.,received 2 greywhite linear cores measuring 1 to 1.2cm. entire tissue processed.,section from the linear cores shows a neoplastic lesion with cells arranged in sheets and cords. cells have moderate to scanty cytoplasm with round to oval hyperchromatic nuclei and prominent nucleoli. few cell clusters are showing moderate amount of clear cytoplasm with centrally placed hyperchromatic nuclei. stroma shows lymphoplasmacytic infiltration. thickened and congested bood vessels are present.,biopsy from left chest wall mass:metastatic deposit of invasive carcinoma known and treated case of carcinoma breast.
TM1700975,micro calcification and in left breast birad 4,left breast lesion core biopsy.,received 4 grey white to grey brown linear core measuring 0.4 to 0.7cm. entire tissue processed.,section from the linear cores shows breast parenchyma harboring a neoplastic lesion arranged in nests sheets and tubular pattern. cells are pleomorphic with scanty to moderate cytoplasm and round to oval hyperchromatic nuclei with prominent nucleoli. extensive areas of dcis (ductal carcinoma in situ) complaisant is seen with comedo necrosis. few areas are also showing clear cell change stroma shows lymphoplasmacytic infiltration.,left breast lesion core biopsy:invasive ductal carcinoma grade ii with extensive ductal carcinoma in situ and comedo necrosis.modified bloom richardson score 7 9(3+2+2)
TM1701268,left breast lump p o carcinoma breast.,biopsy from left breast lump.,received multiple linear grey white to grey brown cores measures 1.2 to 1.4cm in length. entire tissue processed.,sections from the linear core biopsy from breast lump submitted shows normal breast parenchyma along with an infiltative lesion seen in sheets and islands . the cells are large with hyperchromatic nuclei depicting moderate pleomorphism .mitotic figures discerned. there are occasional foci shows admixed lymphomononuclear infiltrate. areas of crush artifacts seen.,invasive ductal carcinoma.modified br score is 8 9 grade iii.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 3 8 9
TM1702814,left breast lump.,biopsy from left breast.,received 5 grey white to grey brown linear cores measures 0.6 to 1cm. entire tissue processed.,section shows linear cores of tissue harboring a lesion arranged in nests islands and cords comprising of atypical cells with round to oval pleomorphic hyperchromatic nuclei and moderate eosinophilic cytoplasm. mitotic figures 7 8 10hpf. stroma shows fibrosis and extensive lymphocytic infiltrates. no necrosis identified.,biopsy from left breast:invasive ductal carcinoma grade 2.modified bloom richardson s score ( 3+2+2) 7 9.
TM1702874,carcinoma breast.,biopsy from breast lesion.,received 4 grey white to grey brown linear cores measures 1 to 1.2m. entire tissue processed.,linear cores of fibrofatty tissue demonstrating sheets of neutrophils and foci of hemorrhage.,biopsy from breast lesion:only inflammatory cells seen.
TM1702960,right breast mass birads v lesion,biopsy from right breast mass,received multiple grey white linear cores measures 1 to 1.3cm. entire tissue is processed,linear cores of breast parenchyma harboring a neoplasm arranged as nests islands and sheets. the neoplastic cells exhibit moderate nuclear pleomorphism and have moderate cytoplasm. areas of necrosis seen,infiltrating ductal carcinoma biopsy from right breast massgrade 2tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
TM1703378,left breast lump p o carcinoma breast.,left breast lump core biopsy.,received four grey white linear cores measuring 1.2 to 1.5cm. entire tissue processed.,h and e stained section shows linear cores of breast parenchyma harboring a neoplastic lesion arranged in cords nests and occasional tubules. the lesional cells are pleomorphic with moderate amount of eosinophilic cytoplasm and pleomorphic hyperchromatic nuclei. few cells have clear cytoplasm. lymphocyte aggregates are also seen.,left breast lump core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 7(3+2+2).
TM1703437,left invasive duct cell carcinoma.,a) left breast conservation surgeryb) deep resected margin.c) left level i ii lymph node.d) level iii lymph node.,a) received lumpectomy specimen measures 10x9x3.5cm. skin ellipse measures 8x3.5cm. cut surface show a grey white lesion measuring 3x2.3x1.5cm located at the following distances from respective margin: superior margin 4.5cm.inferior margin 2.5cm.medial margin 1.5cm. lateral margin 5.5cm.deep margin 1.5cmb) revised deep margin:received single muscle bit measures 3x2.5x0.6cm. entire tissue processed.c) received multiple bits of fibrofatty tissue all together measures 10x8x4cm. largest lymph node 2x1x1cm. cut surface show grey white.d) received multiple fibrofatty tissue all together measures 1x1x0.5cm. entire tissue processed.,a) sections from tumor show breast parenchyma harboring a neoplasm arranged as islands and cords. the neoplastic cells exhibit moderate nuclear pleomorphism have vesicular nuclei conspicuous nucleoli and moderate cytoplasm. extensive peritumoral and intratumoral lymphocytic response seen.lymphovascular invasion seen.all resected margins including deep are free of tumor.b) section shows muscle which is free of tumor.c) section shows 2 15 lymph nodes from level i ii axillary dissection shows metastatic deposits of tumor. no perinodal spread seen.d) section shows 1 lymph node which is free of tumor.,a) invasive ductal carcinoma left breast.grade 3 modified bloom richardson score (8 9)tubule formation 3nuclear pleomorphism 3mitotic figures 2tumor size : 3x2.3x1.5cm.lymphovascular emboli seen.all resected margins are free of tumor.overlying skin is unremarkable.b) deep resected margin is free of tumor.c) 2 15 lymph nodes from left level i ii axillary dissection are free of tumor.d) 1 lymph node from level iii dissection is free of tumor.
TM1703528,carcinoma left breast.,biopsy from left breast.,received 6 grey white linear cores measuring 0.6 to 1.4cm. entire tissue processed.,linear cores of breast tissue infiltrated by a neoplasm arranged as cords tubules and clusters. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm .,biopsy from left breast:invasive ductal carcinoma grade 2.modified bloom richardson score 7 9.tubule formation 3nuclear pleomorphism 2mitotic figures 2 7 9
TM1703972,left breast mass for evaluation.,left breast left modified radical mastecomy.,received in : formalin.laterality : left mrm.total dimensions : medial to lateral : 20cm. superficial to deep :4cm. superior to inferior : 17cm.skin ellipse : 17x5cm. nipple :normal scar surgical defect : not seen.tumor : single.tumour size : 2x1.3x1.2cm. location of tumor : infero lateral quadrantmargins of tumor : irregular. deep margin : 1cm. muscle : absent adjacent breast : fibrofatty tissue. axillary tail : 6x5x3cm.total number of nodes : 14size of largest node :1x1x0.8cm. cut surface grey white.,sections show breast parenchyma harboring a lesion arranged in tubules and nests. the cells are ovoid having moderate amount of cytoplasm vesicular nucleus and prominent nucleoli in few. stroma shows desmoplasia with lymphomononuclear infiltrates. areas of hemorrhage with necrosis are noted.,left breast left modified radical mastectomy: invasive ductal carcinoma carcinoma grade 1.modified br score is 5 9.tubule formation :2nuclear pleomorphism : 2mitotic figures : 1tumor measures 2cm in greatest dimension and is located in the inferior lateral quadrant. ductal carcinoma in situ not identified.lymphovascular invasion identified.perineural invasion not identified.posterior resection margin is free of tumor.nipple and areola is unremarkable.lymph nodes: fourteen lymph nodes metastasis: zero (0 14).summary : left mrm left invasive ductal carcinoma grade 1 measuring 2cm in greatest dimension with lymphovascular invasion.lymph nodes: fourteen lymph nodes metastasis: zero (0 14).pathological stage :pt1cn0.
TM1704118,right breast lump.,biopsy from right breast lump.,received 5 greywhite to grey yellow linear cores measuring 0.6 to 1cm. entire tissue processed.,section from right breast show multiple cores of tissue showing extensive hyalinisation harboring infiltrating lesion arranged in cords and tubules. the lesional cells are round to oval with hyperchromatic nuclei and scant cytoplasm. cells exhibit moderate nuclear pleomorphism. areas of necrosis and hemorrhage noted.,right breast lump biopsy:suggestive of invasive ductal carcinoma grade 2.modified br score : 6 9.tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
TM1704706,left breast lump possibility of carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 0.2 0.8cm. entire tissue is processed.,section shows linear cores of fibroadipose tissue harboring an infiltrative lesion arranged astubules and nests. the cells have moderately pleomoprhic hyperchromatic nucleus and scanty cytoplasm.stroma shows desmoplasia and focal myxoid change.,biopsy from left breast :invasive carcinoma no special type grade 2tubule formation 2nuclear pleomorphism 2mitotic figures (7 8 10hpf) 2 6 9
TM1705697,carcinoma breast,left supraclavicular node biopsy.,received single lymph node measures 2x1.5x1cm. entire tissue processed.,section shows lymph node with a lesion arranged in islands and nest with retraction spaces around . the cells have round nuclei dispersed chromatic few having prominent nucleoli and moderate amount of cytoplasm. stroma shows desmoplasia. mitotic figures discerned . foci of necrosis seen.,left supraclavicular node biopsy:metastatic carcinoma in a known case of carcinoma breast.
TM1705747,carcinoma breast.,lumpectomy specimen from lower upper quadrant of right breast.,received in normal saline one bottle.received lumpectomy specimen measures 9.5xc7x4.5cm.skin ellipse measures 5.5x2cm.surface shows a scar measures 0.8cm.cut surface shows an ill defined grey white firm lesion measures 1.4x1x1cm.located at the following distances from the respective margins:superior margin 3cminferior margin 2.5cmmedial margin 4cmlateral margin 3cmdeep margin 1.5cm.,sections show parenchymal tissue infiltrated by glandular structures nests cordsand trabeculae of malignant epithelial cells showing increased nucleo cytoplasmic ratio pleomorphic vesicular nuclei cytoplasm. at places cribriform and micropapillary pattern is appreciated. these are surrounded by fibrocollagenousconnective tissue and dense aggregates are noted. lymphoplasmacytic infiltrate lymphoid myxoid appearance is present in stroma.lymphovascular emboli not seen.perineural invasion not seen.ductal carcinoma in situ is seen in adjacent parenchyma.the resection margins are free of tumor(superior inferior medial lateral deep),lump right breast:invasive ductal carcinoma grade 2.mbr score 6 9tubule formation 2nuclear pleomorphism 2.mitotic figures 2 6 9 tumor measures 1.4x1x1cm.dcis seen no lvi pni seen all resection margins are free of tumor.
TM1706766,left breast lump possibility of carcinoma breast.,left breast lump core biopsy.,received seven grey white to grey yellow linear cores measures 0.5 to 1cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in nests cords and diffuse sheets. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. areas of ductal carcinoma in situ are seen.,left breast lump core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1) ductal carcinoma in situ of solid cribriform and comedo pattern with intermediate nuclear grade.
TM1706885,right breast mass carcinoma breast.,biopsy from right breast.,received 4 grey white linear cores measures 0.8 to 1.2 cm. entire tissue processed.,section shows tumor cells in nests and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast mass core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
TM1706953,right breast lump.,biopsy from right breast.,received 4 greywhite linear cores measuring 1 to 1.5cm. entire tissue processed.,sections show linear tissue cores harboring an infiltrative lesion arranged in nests and sheets. the individual tumor cells show increased nucleocytoplasmic ratio focal prominent nucleoli and variable amount of eosinophilic cytoplasm. the tumor infiltrates the adipose tissue and fibrocollagenous connective tissue. focal calcification is noted.,usg guided biopsy of right breast mass:invasive ductal carcinoma grade ii.modified br score is 7 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 2 7 9
TM1707336,left breast lump malignant.,left breast lump.,received multiple grey white to grey yellow linear cores measures 1 to 1.5cm. entire tissue processed.,section from the breast parenchyma shows infiltrating neoplasm arranged in glands sheets. the cells are round to oval hyperchromatic nuclei with abundant cytoplasm. the adjacent stroma shows lymphocytic infiltration. mitosis 3 4 0hpf.,left breast lump core biopsy :invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
TM1707604,left breast lump malignant.,biopsy form left breast.,received multiple grey white to grey brown linear cores measures 1 to 1.2cm. entire tissue processed.,linear cores of breast parenchyma harboring a neoplasm arranged as sheets ducts and islands. the neoplastic cells exhibit moderate nuclear pleomorphism have hyperchromatic nuclei and moderate cytoplasm. the intervening stroma is desmoplastic.,biopsy form left breast:invasive ductal carcinoma grade 2modified bloom richardson score is 7 9.tubule formation 3nuclear pleomorphism 2mitotic activity 2 7 9
TM1708121,right breast lump possibility of carcinoma breast.,right breast core biopsy.,received 7 grey white to grey yellow linear cores measures 0.8 1.2cm. entire tissue processed.,section shows tumor cells in tubules and nests . individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast core biopsy :invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
TM1708200,carcinoma breast.,biopsy from breast,received multiple bits of fat altogether measures 1x0.8x0.3cm. entire tissue processed.,section studied from linear cores show abundant hyalinisation of stroma along with mature adipocytes . few atypical cells are seen which are round to oval with scant cytoplasm pleomorphic nucleus. these atypical cells admixed within the stroma along with lymphocytic infiltrate.,biopsy from incisional breast:scant volume of atypical cells suspicious of invasive carcinoma.note:tumor volume inadequate for ihc .case discussed with dr.vipin.
TM1708541,carcinoma right breast.,a) right breast + level i ii lymph nodes.b) sections from level i amp ii lymph nodes.,a) total dimensions : medial to lateral : 19cm. superficial to deep : 4cm. superior to inferior : 14cm.skin ellipse : 17x6cm.nipple : normal.scar surgical defect : not seen.tumors : two in number tumor size :larger tumor measures 2.5x1.8x1.5cm. smaller tumor measures 0.7x0.5x0.5cm.the two tumors are 1.2 cm apartmuscle : 1st 0.3cm 2nd 0.5cm.b) received 1 fibrofatty tissue measures 7x3x2cm.dissection reveals 12 nodes largest matted lymph node measures 3x2x1.8cm.,section from larger tumor (2.5x1.8x1.5cm ) shows sheets of tumor cells exhibiting moderate nuclear pleomorphism and brisk mitotic activity . smaller tumor (0.7 cm ) harbors tumor arranged in nests sheets in papillary pattern with fibrovascular cores arranged in lobules .the neoplastic cells are round to oval scant cytoplasm with pleomorphic vesicular nucleus. mitotic activity is seen. abundant ductal carcinoma in situ (solid type) are seen. focal areas of adenosis is seen in adjacent stroma . nipple areola unremarkable. stroma shows shows intense lymphocytic infiltrate. tissue sections between both tumors is unremarkable.,a) right breast + level i ii lymph nodes:right breast modified radical mastectomy.multifocal carcinoma 2 lesions ( 2.5cm and 0.7 cm ) they are 1.2 cm apart lesion 1 : invasive ductal carcinoma nos grade iii.modified bloom richardson scores is 8 9.tubular formation 3nuclear pleomorphism 2mitotic activity 3 8 9 lesion 2 : invasive ductal carcinoma with papillary features (high nuclear grade).tumor measures 2.5cm in greatest dimension.sections between both tumors are free and measures 1.2cm.ductal carcinoma in situ present (solid 50 )lymphovascular invasion not seen.perineural invasion not seen.nipple aerola unremarkable.posterior margin is free of tumor.b) sections from level i amp ii lymph nodes:isolated 12 lymph nodes 2 show tumor deposits (2 12). no perinodal spread noted.
TM1708550,mass in right breast carcinoma breast .,biopsy from right breast.,received 4 grey white to grey brown linear cores measures 0.6 0.8cm. entire tissue processed.,linear cores of breast tissue harboring atypical cells with hyperchromasia in cords .these cells exhibit crush artifacts . the intervening stroma is elastotic.,biopsy from right breast:atypical cells with extensive crush artefact seen suggestive of invasive carcinoma.needs confirmation.
TM1708579,recurrent right breast sol in chest wall.,chest wall lesion biopsy.,received 3 greywhite linear cores measuring 0.6 to 1cm. entire tissue processed.,section shows cores of breast tissue with an invasive neoplasm in acinar glands nests and cords. the cells show moderate eosinophilic cytoplasm pleomorphic hyperchromatic nuclei and prominent nucleoli. mitosis is increased. stroma is desmoplastic.,chest wall lesion biopsy:invasive carcinoma nst grade ii.mbr score 9tubule formatio: 2nuclear pleomorphism: 2mitotic activity: 2 6 9
TM1708966,carcinoma left breast,biopsy from left breast.,received 3 grey white linear cores measures 0.7 to 0.9cm in largest . entire tissue processed.,section shows cores of breast parenchyma harboring infiltrating lesion arranged in tubules and cords. the lesional cells are round to oval having hyperchromatic nuclei and moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. stroma shows elastosis. mitosis 3 4 10hpf.,biopsy from left breast:invasive carcinoma no special type grade iimodified bloom richardson score is 6 9tubule formation :3nuclear pleomorphism : 2mitotic : 1 6 9
TM1709131,not provide.,left breast biopsy.,received five gray white linear cores measures 0.2 to 1cm. entire tissue processed.,section studied shows multiple linear cores with a tumor arranged in nests and focally in cords. the tumor cells show moderate nuclear pleomorphism increased nuclear cytoplasmic ratio occasional nucleoli and moderate eosinophilic cytoplasm.,biopsy from left breast :invasive ductal carcinoma grade ii.modified bloom richardson score is 7 9tubule formation 3nuclear pleomorphism 2mitosis 2.
TM1709252,left axillary node possibility of metastatic.,left axillary node.,received 4 grey white linear cores measures 1.2 to 1.4 cm. entire tissue processed.,section shows cores of lymph nodal tissue harboring a infiltrating neoplasm with cells in sheets and nests. the neoplastic cells shows eosinophilic to vacuolated cytoplasm hyperchromatic nuclei with moderate pleomorphism and increased mitosis. areas of comedo type necrosis noted.,left axillary node core biopsy :positive for malignancy.suggestive of metastatic carcinoma deposits most possible from breast.
TM1709282,carcinoma right breast.,right breast core biopsy.,received 4 grey white to grey yellow linear cores measures1 1.2cm. entire tissue processed.,section shows cores of breast tissue harboring an invasive neoplasm predominantly composed of spindle cells in sheets and fascicles. the cells show moderate atypia with nuclear hyperchromatic . there is increased mitosis. foci show entrapped duct showing atypical hyperplasia.,right breast core biopsy:spindle cell neoplasmpossibilities include1) malignant phyllodes2)metaplastic carcinoma.comment : larger tissue will be required for further evaluation and typing of the tumor.
TM1800056,right axillary tail lump possibility of axillary tail mass metastasis.,right axillary tail lump biopsy.,received 5 grey white linear cores measures 0.8 0.1cm. entire tissue processed.,section shows multiple linear cores with an infiltrating tumor arranged in sheets. the tumor cells show moderate to marked pleomorphism with round to oval hyperchromatic nuclei and moderate amount of eosinophilic cytoplasm. interspersed lymphocytes are noted in between the tumor cells.,right axillary tail lump biopsy:features suggestive of metastatic carcinoma most possible from breastcomment : ihc done shows tumor cells to be positive for pancytokeratin and negative for lca supporting the above morphological impression.
TM1800153,left breast lesion birads iv lesion.,biopsy from left breast.,received 4 grey white linear cores measures 1 to 1.2cm. entire tissue processed.,section shows cores of fibrocollagenous clusters harboring an invasive neoplasm in the cords nests and glandular pattern. the cells show moderate nuclear pleomorphism hyperchromatism and increased mitotic figures. stroma shows is desmoplasia with scattered inflammation and areas of hyalinisation.,left breast lesion:invasive carcinoma ductal ( nos) modified bloom richardson score is) 3+2+1)6 9 grade ii
TM1800197,suspicious of malignancy lesion.,biopsy from right breast lump.,received multiple grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows linear cores of breast parenchyma infiltrated by islands and nests of neoplastic cells consistent of round to oval dark nuclei few with prominent nucleoli and moderate eosinophilic cytoplasm. mitotic figures 7 8 10hpf . stroma shows extensive hyalinisation and fibrosis along with lymphoplasmacytic infiltrate and focal areas of necrosis.,biopsy from right breast lump:invasive carcinoma nos grade 2modified bloom score is (3+2+2)7 9
TM1800706,left carcinoma breast,left modified radical mastectomy:,received in : formalin procedure : modified radical mastectomy total dimensions : medial to lateral :23cm superficial to deep :2.5cm superior to inferior :15cmskin ellipse : 15x5.5 cm nipple :normal scar surgical defect :not seentumor : singletumour size : 3.4x3x2.5 cm location of tumor : upper outer quadrantmargins of tumor : well circumscribed deep margin : 0.2 cmmuscle : absent adjacent breast : fibrofatty tissueaxillary tail :5.5x4x1.5 cmsize of largest node :1.2x1x0.5 cm cut surface unremarkable,section from the breast parenchyma shows a infiltrating neoplasm arranged in tubules sheets nests and diffuse scattered cells supported by fibrovascular stroma. the neoplastic cells are round to oval vascular nuclei with prominent nucleoli and few with stippled chromatin. abundant eosinophilic granular cytoplasm mild pleomorphic nuclei is seen. areas of desmoplasia. atypical mitotic figures are identified.,left modified radical mastectomy: invasive carcinoma grade iii. modified bloom richardson score is 8 9tubule formation: 3nuclear pleomorphism:2mitotic figures:03tumor measures 3.4 cm in greatest dimension and is located in the upper outer quadrant. ductal carcinoma in situ is not identifiedlymphovascular invasion is identifiedperineural invasion not seenposterior resection margin is free of tumornipple and areola is unremarkable lymph nodes: 10 lymph nodes metastasis: 0(0 10) . b) level ii amp iii :one lymph node isolated shows no tumor deposits.
TM1800884,right breast lump carcinoma breast.,right breast lump biopsy.,received 4 gray white linear cores measures 0.8 to 1 cm. entire tissue processed.,section shows linear tissue cores infiltrated by few neoplastic cells in nests and cords. individual cells show hyperchromatic pleomorphic nucleus with scanty cytoplasm. ductal carcinoma in situ is noted.,right breast lump biopsy :small focus of invasive ductal carcinoma with ductal carcinoma in situ is seen.comment:in view of small focus repeat biopsy may be required for prognostic marker studies.
TM1801031,right breast lump possibility of carcinoma breast.,biopsy from right breast,received 4 grey white linear cores measures 1 1.2cm. entire tissue processed.,linear cores of necrotic tissue. no viable tumor included in the biopsy.,biopsy from right breast:only necrotic tissue seen.suggest repeat biopsy from viable areas
TM1801065,right breast lump birads 5 malignant.,right breast lump core biopsy.,received 6 grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows tumor cells in diffuse sheets and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast lump core biopsy:invasive ductal carcinoma grade 2 modified bloom richardson score is 6(3+2+1).
TM1802402,left breast irregular lesion.,biopsy from left breast lesion.,receive multiple grey white linear cores measures 0.5 0.8cm. entire tissue processed.,section shows linear cores of breast parenchyma harboring an infiltrative neoplasm arranged as nests sheets cords tubules and papillae of neoplastic cells exhibiting increased n c ratio occasional conspicuous nucleoli and scant to moderate amount of eosinophilic cytoplasm.,biopsy from left breast lesion:invasive carcinoma breast with papillary ductal carcinoma in situ.modified bloom richardson score is 6 9(3+2+1).needs confirmation on larger tissue.
TM1802584,carcinoma right breast.,right breast mass core biopsy.,received 4 grey white fragment linear cores measures 0.2 0.3cm. entire tissue processed.,section shows cores of beast tumor cells in tubules nests and cords. individual tumor cells have hyperchromatic nuclei and moderate amount of cytoplasm.,right breast mass core biopsy:suggestive of invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1).
TM1802927,left breast lump rule out carcinoma breast.,biopsy from left breast lump.,received 6 grey white to grey yellow linear cores measures 0.3 0.7cm. entire tissue processed.,section shows multiple linear cores of breast parenchyma harboring an infiltrative lesion arranged in nests and sheets. the neoplastic cells are round to oval with abundant eosinophilic cytoplasm nuclei are hyperchromatic round to oval with moderate nuclear pleomorphism. mitotic activity discerned. stroma showing desmoplastic change.,biopsy from left breast lump:invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9.tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
TM1803344,left breast lump.,left breast lump,received lumpectomy with attached skin ellipse measures 8x6x5cmskin ellipse measures 4.2x3cmmargins are not labelled external surface is irregular inked in green on serial section ill defined fibrotic areas measures 5x4.2x4cm with focal necrotic and cystic changes present. distance of the closest resected margin is 0.3cm from the lesion.,multiple section show necrotic areas with acute inflammatory cells consisting of polymorphonuclear leucocytes. in other areas ducts are surrounded by periductal chronic inflammatory cells composed of lymphocytes plasma cells and foamy histiocytes with dilatation of some ducts and foreign body giant are seen. there is no evidence of ductal carcinoma in situ or malignancy. the skin and subcutaneous tissue appear normal. the closest resected margin is 0.3 from the lesion.,left breast lump:abscess with duct ectasia.
TM1803396,carcinoma right breast.,biopsy from right beast,received multiple grey white linear cores measures 0.8 1cm. entire tissue processed.,section shows multiple cores of tissue with ductal elements showing extensive crush artifacts . surrounded by lymphoplasmacytic infiltration.,biopsy from right beast:the features are suspicious for malignancy however er pr is not feasible due to extensive crush artifactsuggest repeat biopsy if clinically indicated.
TM1803421,lump left breast.,biopsy from left breast.,received single fibrofatty tissue measures 3x2.5x1cm. sutured surface inked.,section shows breast parenchyma harboring an invasive neoplasm arranged in tubules and cords.the lesional cells have round hyperchromatic nucleus inconspicuous nucleoli and moderate cytoplasm. ductal carcinoma in situ component is seen and is solid and also comedonecrosis pattern seen .,biopsy from left breast:invasive ductal carcinoma with dcis grade 2modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
TM1804283,carcinoma right breast.,a) right breast lump wide excisionb) right axillary clearance.,a) received excision specimen measures 10 x 5 x 3.5 cm. cut surface grey white circumscribed margin measures 2.5 x 2.1 x 2 cm. distance from margins: closest margin 1.5cmother margin 2.5cmdeep margin 0.3cmrepresentative sections are submitted.b) axillary tail measures 5 x 4 x 3 cm.largest lymph node measures 1 x 0.8 x 0.7cm. cut section grey white.,section shows tumor cell in diffuse sheets nests and tubular pattern. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm. lymphovascular invasion is identified. perineural invasion is not identified.,a) right breast lump wide excision:invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1). tumor measure 2.5 cm in greatest dimension. lymphovascular invasion is identified. perineural invasion is not identified. ductal carcinoma in situ component is not seen. all margins of resection are free of tumor.b) right axillary clearance: five out of eleven lymph nodes show metastatic tumor deposits with extranodal extension(5 11). size of the largest tumor deposit measure 0.6 cm in greatest dimension.pathological stage : pt2n2a
TM1804288,left breast lump.,biopsy from left breast lump.,received 5 grey linear cores measures each 1.5cm. entire tissue processed.,section shows linear cores of fibrocollagenous tissue harboring an invasive neoplasm arranged in glandular pattern solid nests trabecular papillary pattern. individual tumor cells are round to cuboidal with moderate eosinophilic cytoplasm pleomorphic hyperchromatic nuclei and prominent nucleoli. occasional mitotic figures seen. stroma is desmoplastic.,biopsy from left breast lump. :invasive carcinoma with papillary features. grade ii.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9
TM1804539,right breast lump carcinoma breast.,biopsy from right breast biopsy.,received 5 linear cores measures 0.5 0.6cm. entire tissue processed.,section shows multiple cores of breast parenchyma harboring infiltrating lesion arranged in nests cords tubules. the lesional cells are round to oval having hyperchromatic nuclei moderate cytoplasm. cells exhibit moderate nuclear pleomorphism. stroma is desmoplastic mitosis 2 3 10 hpf.,biopsy from right breast biopsy:invasive ductal carcinoma grade i.modified bloom richardson score is 5 9(2+2+1).
TM1804651,mastectomy specimen.,laterality : left breast mastectomy specimen. total dimensions :medial lateral : 20cm. superficial deep : 10 cm. superior inferior : 12 cm.skin ellipse : 19x11cm.nipple : retracted. scar surgical defect :suture scar at a distance of 1cm from nipple areola. tumor : singletumor size : 8x6x5cm. grey white firm to viable with slit like spaces. location of tumor : all quadrants. margins of tumor : well defineddeep margin : 0.7cm. muscle : present. adjacent breast : fibrofatty tissue.,multiple sections studied from the breast parenchyma show a well circumscribed neoplasm with biphasic pattern. there is expansion and increased cellularity of the stromal component and stromal overgrowth. leaf like fronds of stroma lined by epithelial lining are noted. focally there is presence of an invasive neoplasm composed of epithelial cells arranged in tubules focal cribriform and micropapillary pattern focally lining the stromal component. the neoplastic epithelial cells depict increased nuclei cytoplasmic ratio pleomorphic vesicular nuclei prominent nucleoli and moderate amount of eosinophilic cytoplasm. the stroma surrounding the neoplastic glands shows dense desmoplasia. few tubules are cystically dilated and their lumen shows necrosis. cribriform ductal carcinoma in situ noted. the stromal component shows 3 4mf 10hpf. no evidence of lymphovascular emboli or perineural invasion.,mastectomy,invasive ductal carcinoma arising in a background of benign phyllodes tumor.tumor is located in all the quadrants. invasive ductal carcinoma component measures approximately 3 cm in greatest dimension. phyllodes tumor measures 8cm in greatest dimension. no evidence of perineural invasion or lymphovascular emboli ductal carcinoma in situ seen cribriform micropapillary and solid pattern. measures approximately 0.8cm in greatest dimension.
TM1804680,left breast carcinoma.,a) left breast left modified radical mastectomy.b) level i and iii lymph nodes.,a) received in : formalinprocedure : left modified radical mastectomy.laterality : left breast.total dimensions :medial lateral : 9 cm superficial deep : 2.5 cm superior inferior : 8.5 cmskin ellipse : 8x5 cmnipple : unremarkabletumor : singletumor size : 2.5 x 2 x 1.7 cmlocation of tumor : 6 o clockmuscle : 3x2x1 cmadjacent breast : fibrofatty tissueaxillary tail : 4x3x2 cm b) received fibrofatty tissue measures 6x5x2 cm largest lymph node measures 2x1x1 cm.,section from the shows breast parenchyma showing infiltrating neoplasm arranged in sheets nests and tubules. the cells are round to oval vesicular nuclei prominent nucleoli abundant eosinophilic cytoplasm. adjacent parenchyma show lymphoplasmacytic infiltrates. mitoses 4 5 10 hpf.,left breast left modified radical mastectomy :invasive ductal carcinoma grade 2. tumor measures 2.5 cm in greatest dimension. modified bloom richardson score is 6(3+2+1). ductal carcinoma in situ of solid and cribriform pattern with intermediate nuclear grade is seen. lymphovascular invasion is not seen. perineural invasion is not seen. posterior resection margin is free of tumor. nipple and aerola is unremarkable.lymph nodes : fifteen lymph nodes are identified all are free of tumor (0 15).pathological stage : pt2n0
TM1804946,left breast lump possibility of carcinoma breast.,left breast lump biopsy.,received five grey white linear cores measures 1 2.5 cm. entire tissue processed.,section shows larger areas of hemorrhage with few atypical cells showing focal spindle cell differentiated.,left breast lump biopsy:large areas of hemorrhage with few atypical cells showing focal spindle cell differentiation.no definite opinion is possible.suggest repeat biopsy or excision of the lump for further confirmation.
TM1806253,left breast lump.,biopsy from left breast.,received multiple fragmented linear cores measures 0.5 to 1cm. entire tissue processed.,sections studied show fibrous tissue harboring an infiltrating lesion arranged in nests and vague tubules. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nuclei and prominent nucleoli and prominent nucleoli in few. stroma is desmoplastic with dense lymphomononuclear cells infiltrate. areas of hemorrhage necrosis and crush artifacts are seen.,biopsy from left breast:invasive carcinoma nst grade 3.tubular formation 2nuclear pleomorphism 3mitotic activity 3 8 9
TM1806947,carcinoma right breast.,right breast right modified radical mastectomy.,received in : formalin procedure : modified radical mastectomy laterality : righttotal dimensions : medial to lateral : 11 cm. superficial to deep : 3 cm. superior to inferior : 7 cm.skin ellipse : 9 x 6 cmnipple : normal scar surgical defect : not seentumor : single tumor size : 2 x 1.5 x 1 cm location of tumor : central quadrantmargins of tumor : irregular deep margin : 0.3cmmuscle : absentadjacent breast : fibrofatty tissue axillary tail : 6 x 4 x 3 cm.total number of nodes : 12 nodes.size of largest node : 1.5 x 1 x 0.8 cm. cut surface grey brown.representative sections are submitted.,section studied from breast parenchyma composed tumor cells arranged in tubules of varying sizes. the tumor cells are cuboidal with scant eosinophilic cytoplasm vesicular nuclei and inconspicuous nucleoli. adjacent ducts shows cystic change with few ducts showing duct carcinoma in situ. occasional mitosis necrosis seen. stroma shows desmoplasia.,right breast right modified radical mastectomy:invasive ductal carcinoma grade 1. modified bloom richardson score is 5(2+2+1). tumour is unifocal and is located in the central quadrant. tumor measures 2.0 cm in greatest dimension. ductal carcinoma in situ not identified lymphovascular invasion not identified. perineural invasion not identified posterior resection margin is free of tumor. nipple and areola is free of tumor.lymph nodes:twelve lymph nodes are identified free of tumor(0 12).pathological stage pt1cn0
TM1808009,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 grey white linear cores measures 1.5 to 2cm. entire tissue processed.,section shows cores of breast tissue infiltrated by tumor cells in cords and nests. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,biopsy from left breast lump :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
TM1808277,carcinoma bilateral breast.,a) breast biopsy laterality not specified. b) site not specified biopsy.,a) breast biopsy laterality not specified. received 3 grey white linear core measures 0.5 to 0.8cm. entire tissue processed. b) site not specified biopsy. received 3 grey white linear core measures 0.5 to 0.8cm. entire tissue processed.,a) section studied shows breast parenchyma with an infiltrating lesion arranged in nests islands and cords. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures are discerned with mild lymphomononuclear cell infiltrates. areas of hemorrhage seen. b) section studied shows linear cores of fibrous tissue with an infiltrating lesion arranged in cords and singly scattered cells. the cells are oval having moderate amount of cytoplasm hyperchromatic pleomorphic nucleus with prominent nucleoli in few. mitotic figures are discerned. stroma is desmoplastic.,a) breast biopsy laterality not specified. invasive carcinoma nst grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........b) site not specified biopsy :invasive carcinoma nst grade 2.modified bloom richardson score is 6 9tubule formation : 3nuclear pleomorphism : 2mitotic figures : 1 6 9 .........please correlate clinically.
TM1808487,left breast lump birads 4c.,left breast core biopsy.,received 4 grey white linear core measures 1 to 1.5 cm. entire tissue processed.,section shows tumor cells in sheets and cords. individual cells have hyperchromatic nuclei and moderate amount of cytoplasm.,left breast core biopsy :invasive ductal carcinoma grade 2. modified bloom richardson score is 6(3+2+1).
TM1808637,ca breast trucut biopsy idc grade 1 h 18 8669,left breast modified radical mastectomy,received already grossed breast specimen measures 19x16x7cm. skin ellipse 13x8cm. n a retracted surgical defect not seen. axillary tail not seen attached to the specimencur surface tumor in retroreolar region measures 2.3x1x0.8cm. margins are ill defined. deep margin 1.5cm. on dissection of fat 3 nodes isolated,sections from the breast lesion show an invasive neoplasm in tubules linear cords nests and singly scattered forms. the cells have moderate cytoplasm round nuclei with mild to moderate atypia. few lymphoid aggregates noted in the adjacent breast. stroma is hyalinized.,left breast modified radical mastectomy ( already grossed) invasive carcinoma nstihc e cadherin positive. in view of e cadherin positivity it is invasive ductal carcinoma nst grade 1modified bloom richardson score is (3+1+1) 4 9lymphovascular invasion or perineural invasion identified skin nipple and areola are unremarkable on further dissection 3 nodes isolated one of three nodes shows tumour deposits for exact tumor size total lymph nodes involved and status of margins please refer to original report.
TM1809463,left axillary dissection.,left axillary lymph node.,received fibrofatty tissue measures 15x9x5cm largest lymph nodes measures 3x2.5x2.5cm cut surface homogenous grey white,multiple sections examined show eleven lymph nodes three of which show infiltration by tumor in clusters and nests. the tumor cells are round to polygonal with high n c ratio enlarged vesicular nuclei and moderate to abundant eosinophilic cytoplasm. perinodal spread is not seen.,left axillary lymph node:metastatic poorly differentiated carcinoma favor breastsuggest ihc three of eleven lymph nodes isolated show tumor deposits(3 11)please correlate with clinical findings
TM1900002,lump right breast.,right breast lump biopsy.,received multiple linear core biopsy bits measures 0.5 to 1.5cm. entire tissue processed.,section show linear cores of breast parenchyma harboring tumor infiltrating as nests and tubules composed of round to oval cells with high n:c ratio vesicular nucleus conspicuous nucleolus and moderate cytoplasm. nuclear pleomorphism is mild and occasional mitosis is seen. stroma shows desmoplasia.,right breast lump biopsy:invasive ductal carcinoma grade 2. modified bloom richardson score is (3+2+1).
TM1900411,right and left breast.,a) right breast.b) left breast.,a) received single grey white linear soft tissue bits measures 0.5cm. entire tissue processed.b) received two grey white linear cores measures 0.2 to 0.05 cm. entire tissue processed.,a) section from bottle labelled as right shows linear cores of fibrous tissue with an infiltrating lesion arranged in nests and singly scattered cells. the cells are ovoid having moderate amount of cytoplasm and hyperchromatic nucleus and prominent nucleoli. stroma is desmoplastic with scattered lymphomononuclear infiltrates. b) section from bottle labelled as left shows linear cores of fibrous tissue with cellular lesion arranged in papillary pattern.the cells are ovoid having moderate amount of cytoplasm and hyperchromatic nucleus . stroma is desmoplastic.,a) right breast : invasive ductal carcinoma grade 2.modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9 b) left breast:papillary neoplasm.suggest ihc.
TM1900780,left breast lump carcinoma breast.,biopsy from left breast lump.,received 4 linear cores grey white measures 1 to 1.5cm. entire tissue processed.,section show linear cores of breast parenchyma showing an infiltrating lesion composed of sheets and nests of dysplastic ductal cells showing moderate anisonucleosis hyperchromatic nuclei and prominent nucleoli. the intervening stroma shows moderate lymphomononuclear infiltrates and desmoplasia.,biopsy from left breast lump. :invasive carcinoma nst left breast. modified bloom richardson score is 6 9tubule formation : 2nuclear pleomorphism : 2mitotic figures : 2 6 9
TM1901125,left breast lump carcinoma breast.,left breast biopsy.,received 4 grey white linear cores measures 1.5 to 1.8cm. entire tissue processed.,section studied shows cores of breast parenchyma harbors infiltrative lesion arranged in sheets and nests. the cells are oval have pleomorphic hyperchromatic nuclei inconspicuous nucleoli and moderate amount of cytoplasm. mitotic activity is discerned. few areas shows fascicles and bundles of spindle cells have pleomorphic hyperchromatic elongated nuclei inconspicuous nuclear and moderate amount of cytoplasm. stroma shows lymphoplasmacytic infiltrate and area of necrosis.,left breast biopsy :invasive carcinoma grade 2. modified bloom richardson score is (3+2+2).
TM1901467,left breast lump carcinoma breast.,biopsy from left breast.,received five grey white linear cores measures 0.8 to 1.5cm. entire tissue processed.,section studied shows fibrocollagenous tissue infiltrated by neoplastic cells arranged in cords and nests. the cells have round hyperchromatic nuclei and moderate cytoplasm. mitotic activity is discerned.,biopsy from left breast lump :invasive carcinoma grade 2. modified bloom richardson score is 6(3+2+1).comment : in view of tumor cells in cords and nests suggest further confirmation of lobular differentiation on larger specimen.
TM1902230,carcinoma right breast.,biopsy from right breast.,received multiple grey white linear cores measures 0.8 to 1cm. entire tissue processed.,section shows linear cores of fibrous tissue with an infiltrating lesion arranged in nests cords and focal tubular pattern. the cells are ovoid having moderate amount of cytoplasm hyperchromatic nucleus and prominent nucleoli. mitotic figures (4 5 10hpf) are discerned. stroma is desmoplastic with areas of hemorrhage and necrosis. focal interspersed mild lymphomononuclear infiltrates.,biopsy from right breast:invasive carcinoma nst grade 2.modified bloom richardson score is 6 9.tubular formation 3nuclear pleomorphism 2mitotic activity 1 6 9
TM1902591,left breast lump fibroadenoma carcinoma breast.,biopsy from left breast lump.,received multiple grey white linear cores measures 2 to 2.5 cm. entire tissue processed.,the section shows cores of breast tissue exhibiting benign bilayered ducts showing round to elongated luminal profiles with increased intervening stroma. focal sclerosing adenosis is seen. occasional ducts show lamina filled with cells showing mild to moderate nuclear enlargement.,biopsy from left breast lump:proliferative breast disease with features are suggestive of atypical ductal hyperplasia and adenosis.comment:suggest excision of the lump if clinically indicative of invasive malignancy.