RBD Mutations,hACE2 Mutations,RBD Source,hACE2 Source,Pre-Omicron RBD Experiment,Pre-Omicron hACE2 Experiment,Omicron BA.2 Experiment
"K417N, E484K, N501Y",H34A,"Beta Variant, WHO",Chan et al. (2020),X,X,X
"K417N, E484K, N501Y",L79I,"Beta Variant, WHO",Chan et al. (2020),X,X,X
"K417N, E484K, N501Y",L79T,"Beta Variant, WHO",Chan et al. (2020),X,X,X
"K417N, E484K, N501Y",L79V,"Beta Variant, WHO",Chan et al. (2020),X,X,X
"K417N, E484K, N501Y",L79W,"Beta Variant, WHO",Chan et al. (2020),X,X,X
"K417N, E484K, N501Y",L79Y,"Beta Variant, WHO",Chan et al. (2020),X,X,X
"K417N, E484K, N501Y",N330F,"Beta Variant, WHO",Chan et al. (2020),X,X,X
"K417N, E484K, N501Y",N330W,"Beta Variant, WHO",Chan et al. (2020),X,X,X
"K417N, E484K, N501Y",N330Y,"Beta Variant, WHO",Chan et al. (2020),X,X,X
"K417N, E484K, N501Y",T92H,"Beta Variant, WHO",Chan et al. (2020),X,X,X
"K417N, E484K, N501Y","L79R, Q24E","Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y",N330R,"Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y",R393E,"Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y","T27Y, L79T, E35D","Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y","T27Y, L79T, K31W","Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y","T27Y, L79T, N330Y, A386L","Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y","T27Y, L79T, N330Y,E35D","Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y","T27Y, L79T, N330Y,K31W","Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y","T27Y, L79T, N330Y,N90E","Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y","T27Y, L79T, N330Y,T92C","Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y","T27Y, L79T, N330Y,T92C,E35D","Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y","T27Y, L79T, N330Y,T92S","Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y","T27Y, L79T, N90E","Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y","T27Y, L79T, T92C","Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y","T27Y, L79T, T92C, E35D","Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y","T27Y, L79T, T92S","Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y","T27Y,N330Y, A386L","Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y","T92C, K31W","Beta Variant, WHO",combination,X,X,X
"K417N, E484K, N501Y",D30M,"Beta Variant, WHO",visual inspection,X,X,X
"K417N, E484K, N501Y","D30M, H34E","Beta Variant, WHO",visual inspection,X,X,X
"K417N, E484K, N501Y",E35D,"Beta Variant, WHO",visual inspection,X,X,X
"K417N, E484K, N501Y",G326E,"Beta Variant, WHO",visual inspection,X,X,X
"K417N, E484K, N501Y",G326N,"Beta Variant, WHO",visual inspection,X,X,X
"K417N, E484K, N501Y",G326Q,"Beta Variant, WHO",visual inspection,X,X,X
"K417N, E484K, N501Y",H34E,"Beta Variant, WHO",visual inspection,X,X,X
"K417N, E484K, N501Y",H34Q,"Beta Variant, WHO",visual inspection,X,X,X
"K417N, E484K, N501Y",K31R,"Beta Variant, WHO",visual inspection,X,X,X
"K417N, E484K, N501Y",K31W,"Beta Variant, WHO",visual inspection,X,X,X
"K417N, E484K, N501Y",K353R,"Beta Variant, WHO",visual inspection,X,X,X
"K417N, E484K, N501Y",T27I,"Beta Variant, WHO",visual inspection,X,X,X
"K417N, E484K, N501Y",T92C,"Beta Variant, WHO",visual inspection,X,X,X
"K417N, E484K, N501Y",Wild type,"Beta Variant, WHO",Wild type,X,X,X
"K417N, L452R, T478K",Wild type,"Delta Plus Variant, WHO",Wild type,X,X,X
"L452R, T478K",H34A,"Delta Variant, WHO",Chan et al. (2020),X,X,X
"L452R, T478K",L79I,"Delta Variant, WHO",Chan et al. (2020),X,X,X
"L452R, T478K",L79T,"Delta Variant, WHO",Chan et al. (2020),X,X,X
"L452R, T478K",L79V,"Delta Variant, WHO",Chan et al. (2020),X,X,X
"L452R, T478K",L79W,"Delta Variant, WHO",Chan et al. (2020),X,X,X
"L452R, T478K",L79Y,"Delta Variant, WHO",Chan et al. (2020),X,X,X
"L452R, T478K",N330F,"Delta Variant, WHO",Chan et al. (2020),X,X,X
"L452R, T478K",N330W,"Delta Variant, WHO",Chan et al. (2020),X,X,X
"L452R, T478K",N330Y,"Delta Variant, WHO",Chan et al. (2020),X,X,X
"L452R, T478K",T92H,"Delta Variant, WHO",Chan et al. (2020),X,X,X
"L452R, T478K","L79R, Q24E","Delta Variant, WHO",combination,X,X,X
"L452R, T478K",N330R,"Delta Variant, WHO",combination,X,X,X
"L452R, T478K",R393E,"Delta Variant, WHO",combination,X,X,X
"L452R, T478K","T27Y, L79T, E35D","Delta Variant, WHO",combination,X,X,X
"L452R, T478K","T27Y, L79T, K31W","Delta Variant, WHO",combination,X,X,X
"L452R, T478K","T27Y, L79T, N330Y, A386L","Delta Variant, WHO",combination,X,X,X
"L452R, T478K","T27Y, L79T, N330Y, E35D","Delta Variant, WHO",combination,X,X,X
"L452R, T478K","T27Y, L79T, N330Y, K31W","Delta Variant, WHO",combination,X,X,X
"L452R, T478K","T27Y, L79T, N330Y, N90E","Delta Variant, WHO",combination,X,X,X
"L452R, T478K","T27Y, L79T, N330Y, T92C","Delta Variant, WHO",combination,X,X,X
"L452R, T478K","T27Y, L79T, N330Y, T92C, E35D","Delta Variant, WHO",combination,X,X,X
"L452R, T478K","T27Y, L79T, N330Y, T92S","Delta Variant, WHO",combination,X,X,X
"L452R, T478K","T27Y, L79T, N90E","Delta Variant, WHO",combination,X,X,X
"L452R, T478K","T27Y, L79T, T92C","Delta Variant, WHO",combination,X,X,X
"L452R, T478K","T27Y, L79T, T92C, E35D","Delta Variant, WHO",combination,X,X,X
"L452R, T478K","T27Y, L79T, T92S","Delta Variant, WHO",combination,X,X,X
"L452R, T478K","T27Y, N330Y, A386L","Delta Variant, WHO",combination,X,X,X
"L452R, T478K","T92C, K31W","Delta Variant, WHO",combination,X,X,X
"L452R, T478K",D30M,"Delta Variant, WHO",visual inspection,X,X,X
"L452R, T478K","D30M, H34E","Delta Variant, WHO",visual inspection,X,X,X
"L452R, T478K",E35D,"Delta Variant, WHO",visual inspection,X,X,X
"L452R, T478K",G326E,"Delta Variant, WHO",visual inspection,X,X,X
"L452R, T478K",G326N,"Delta Variant, WHO",visual inspection,X,X,X
"L452R, T478K",G326Q,"Delta Variant, WHO",visual inspection,X,X,X
"L452R, T478K",H34E,"Delta Variant, WHO",visual inspection,X,X,X
"L452R, T478K",H34Q,"Delta Variant, WHO",visual inspection,X,X,X
"L452R, T478K",K31R,"Delta Variant, WHO",visual inspection,X,X,X
"L452R, T478K",K31W,"Delta Variant, WHO",visual inspection,X,X,X
"L452R, T478K",K353R,"Delta Variant, WHO",visual inspection,X,X,X
"L452R, T478K",T27I,"Delta Variant, WHO",visual inspection,X,X,X
"L452R, T478K",T92C,"Delta Variant, WHO",visual inspection,X,X,X
"L452R, T478K",Wild type,"Delta Variant, WHO",Wild type,X,X,X
"K417T, E484K, N501Y",Wild type,"Gamma Variant, WHO",Wild type,X,X,X
"K417R, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, N501Y",Wild type,GISAID,Wild type,X,X,X
"N440S, N501Y",Wild type,GISAID,Wild type,X,X,X
"F490S, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, L452R, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"R346S, N394S, Y449N, F490R, N501Y",Wild type,GISAID,Wild type,X,X,X
"Y449H, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"R346K, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, N501Y",Wild type,GISAID,Wild type,X,X,X
"S477N, E484K",Wild type,GISAID,Wild type,X,X,X
"K417T, T470N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478R, E484Q",Wild type,GISAID,Wild type,X,X,X
"L452R, S477I, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, S494L",Wild type,GISAID,Wild type,X,X,X
"L452Q, F490S",Wild type,GISAID,Wild type,X,X,X
"V367L, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"R346S, L452R, S477N",Wild type,GISAID,Wild type,X,X,X
"G339D, S371F, S373P, S375F, D405N, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"R346S, L452R",Wild type,GISAID,Wild type,X,X,X
"Y449N, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, E484K",Wild type,GISAID,Wild type,X,X,X
"Q414K, N450K",Wild type,GISAID,Wild type,X,X,X
"R346K, K417N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, E484A",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
L452R,Wild type,GISAID,Wild type,X,X,X
"L452R, E484Q",Wild type,GISAID,Wild type,X,X,X
"N440K, E484K",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"E484K, S494P",Wild type,GISAID,Wild type,X,X,X
"L452R, S477G, T478K",Wild type,GISAID,Wild type,X,X,X
"K444N, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"V445A, E484K",Wild type,GISAID,Wild type,X,X,X
"Q414H, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
V367F,Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"V362F, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, L455F, T478K",Wild type,GISAID,Wild type,X,X,X
"R346K, V483F, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"A372P, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"R346K, E484K, N501Y, A522V",Wild type,GISAID,Wild type,X,X,X
"N354S, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"P384L, Y449H, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"R346K, E484K, N501Y, A520S",Wild type,GISAID,Wild type,X,X,X
"A352S, G446S, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"R346K, P384L, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"Y449H, T478K, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417N, E484K, N501Y, A522S",Wild type,GISAID,Wild type,X,X,X
"K417T, A475S, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"R346K, K444N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"R346K, K417Q, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339S, R346K, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"Y449H, N460K, G485V, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, S494P, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417N, E484K, N501Y, A522V",Wild type,GISAID,Wild type,X,X,X
"K444R, L452R, S477N, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, S477I, T478K, P499R",Wild type,GISAID,Wild type,X,X,X
"K417N, T478R, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"R346K, Y449N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"F374Y, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"A344S, L452R, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"G413R, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, N501Y, P521S",Wild type,GISAID,Wild type,X,X,X
"P337S, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, S477I, T478K, V483F",Wild type,GISAID,Wild type,X,X,X
"P384L, L452R, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, G496S, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, V483F, Q493E",Wild type,GISAID,Wild type,X,X,X
"K417T, S477I, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"T385I, G446S, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"K417N, N450D, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, Q493L, N501Y",Wild type,GISAID,Wild type,X,X,X
"R408I, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, N501Y, A522V",Wild type,GISAID,Wild type,X,X,X
"T385I, L452R, T478K, E484A",Wild type,GISAID,Wild type,X,X,X
"E340D, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K444R, G446V, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"A348S, L452R, S477I, T478K",Wild type,GISAID,Wild type,X,X,X
"A372S, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"V382L, K417N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, K444R, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"R346I, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, K458N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, P479S, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, D427E, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417N, T478K, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, T478I, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417N, S477I, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, S477N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, N501Y, T523N",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, N501Y, L517F",Wild type,GISAID,Wild type,X,X,X
"K417N, E484K, N501Y, E516Q",Wild type,GISAID,Wild type,X,X,X
"K417T, D427N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, S477I, T478K, N501T",Wild type,GISAID,Wild type,X,X,X
"A411S, L452R, T478K, A522V",Wild type,GISAID,Wild type,X,X,X
"Q414K, G446D, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F",Wild type,GISAID,Wild type,X,X,X
"K417T, K444M, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, S494P, G504S",Wild type,GISAID,Wild type,X,X,X
"S349P, L452R, T478K, E484V",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, S477N, T478K",Wild type,GISAID,Wild type,X,X,X
"G339D, E340K, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"A372V, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, S477R, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, P479S, V483F",Wild type,GISAID,Wild type,X,X,X
"G446S, L452R, T478K, A520S",Wild type,GISAID,Wild type,X,X,X
"R408S, L452R, T478K, L517F",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, V511I",Wild type,GISAID,Wild type,X,X,X
"K417T, D427H, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"A344T, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K356E, V367F, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"K417T, D428H, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"T385I, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, S459F, T478K, A522V",Wild type,GISAID,Wild type,X,X,X
"K444M, L452R, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"K417N, E484K, N501Y, S514F",Wild type,GISAID,Wild type,X,X,X
"Q409E, L452R, T478K, A522S",Wild type,GISAID,Wild type,X,X,X
"K356R, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, T430I, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"A411S, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"A372V, L452R, T478K, E484K",Wild type,GISAID,Wild type,X,X,X
"L452R, L461I, E465D, T478K",Wild type,GISAID,Wild type,X,X,X
"R346K, L452R, T478R, E484Q",Wild type,GISAID,Wild type,X,X,X
"S373L, K417N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, A520S, A522V",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, S477I, T478K",Wild type,GISAID,Wild type,X,X,X
"S371A, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"Y369H, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"N440K, L452R, T478K, F490L",Wild type,GISAID,Wild type,X,X,X
"K417N, E484K, N501Y, A520S",Wild type,GISAID,Wild type,X,X,X
"S373L, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417M, G446V, E484Q, N501Y",Wild type,GISAID,Wild type,X,X,X
"V382L, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"V367F, K417N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, E484Q, F490L",Wild type,GISAID,Wild type,X,X,X
"A344S, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"R408S, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"V362F, L452R, T478K, A522V",Wild type,GISAID,Wild type,X,X,X
"G339S, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L390F, T393S, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, S477I, T478K, S494P",Wild type,GISAID,Wild type,X,X,X
"A352V, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, D427Y, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"V367L, L452R, T478K, A520S",Wild type,GISAID,Wild type,X,X,X
"N440K, L452R, T478K, E484K",Wild type,GISAID,Wild type,X,X,X
"A352V, L452R, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"K417T, K462R, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, T478K, N501T",Wild type,GISAID,Wild type,X,X,X
"K378N, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"A411S, L452R, S477I, T478K",Wild type,GISAID,Wild type,X,X,X
"K417T, G446V, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, V483F, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, N501Y, A522S",Wild type,GISAID,Wild type,X,X,X
"K417T, Y449S, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, T470I, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"V367F, L452R, T478K, V511L",Wild type,GISAID,Wild type,X,X,X
"L452R, T470I, T478K",Wild type,GISAID,Wild type,X,X,X
"V367H, L452R, T478K, Y508H",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, G476D, T478K",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, L452R, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, N501Y, A520S",Wild type,GISAID,Wild type,X,X,X
"R346K, L452R, L455F, N501Y",Wild type,GISAID,Wild type,X,X,X
"A419S, L452R, T478K, N481S",Wild type,GISAID,Wild type,X,X,X
"K417T, L452R, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, S477N, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"R346S, L452R, T470I, T478K",Wild type,GISAID,Wild type,X,X,X
"K444R, L452R, T478K, F490S",Wild type,GISAID,Wild type,X,X,X
"T376I, L452R, S477I, T478K",Wild type,GISAID,Wild type,X,X,X
"K417T, V445A, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"A348T, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"V382L, L452R, T478K, P479L",Wild type,GISAID,Wild type,X,X,X
"K417T, D428Y, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, N501Y, Y508H",Wild type,GISAID,Wild type,X,X,X
"L452R, K462R, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"L452R, Y453F, S459F, T478K",Wild type,GISAID,Wild type,X,X,X
"A372T, L452R, T478K, L517F",Wild type,GISAID,Wild type,X,X,X
"P384S, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, N501Y, A522P",Wild type,GISAID,Wild type,X,X,X
"K417N, V433I, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"T376I, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"S373P, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K356R, L452R, T478K, N481Y",Wild type,GISAID,Wild type,X,X,X
"N334K, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"R346K, K417N, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"P384S, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"Q414K, G446V, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"K417T, G476S, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, S477N, T478K",Wild type,GISAID,Wild type,X,X,X
"V367L, G446V, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, N501Y, V503F",Wild type,GISAID,Wild type,X,X,X
"R403K, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, Y449H, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, P479L, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, F490Y, N501Y",Wild type,GISAID,Wild type,X,X,X
"N354K, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, P463S, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"V362I, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, Q493E, A522S",Wild type,GISAID,Wild type,X,X,X
"D427Y, L452R, S459F, T478K",Wild type,GISAID,Wild type,X,X,X
"L335F, L452R, L455F, T478K",Wild type,GISAID,Wild type,X,X,X
"K417T, Y453F, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"A352D, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"G404C, L452R, T478K, Y508C",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, V483A, S494P",Wild type,GISAID,Wild type,X,X,X
"L452R, T470I, T478K, P479S",Wild type,GISAID,Wild type,X,X,X
"A344S, L452R, T478K, P479H",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, P479S, A520S",Wild type,GISAID,Wild type,X,X,X
"L452R, Y453F, T478K, P499R",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"P384L, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"T376I, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"A344S, L452R, T478K, S494P",Wild type,GISAID,Wild type,X,X,X
"K444R, L452Q, F490S, P521R",Wild type,GISAID,Wild type,X,X,X
"W353F, K417N, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, K458N, T478K",Wild type,GISAID,Wild type,X,X,X
"K417T, T478K, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417N, G446V, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"A352S, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"A348S, G446V, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"D389E, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"R346G, L452R, S477I, T478K",Wild type,GISAID,Wild type,X,X,X
"R346K, L452R, T478K, V503F",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, N501Y, V503L",Wild type,GISAID,Wild type,X,X,X
"S373L, G446V, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"K356N, K417N, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, T478K, A522V",Wild type,GISAID,Wild type,X,X,X
"R346S, L452R, G476S, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, P479S, P499R",Wild type,GISAID,Wild type,X,X,X
"K417N, L452R, T478K, P479L",Wild type,GISAID,Wild type,X,X,X
"A348S, S359N, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"N440K, G446V, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"K356R, L452R, T478K, A520S",Wild type,GISAID,Wild type,X,X,X
"K417T, G446S, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, P463S, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417N, L452R, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"T430I, G446V, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, E484Q, E516Q",Wild type,GISAID,Wild type,X,X,X
"K356R, L452R, S477G, T478K",Wild type,GISAID,Wild type,X,X,X
"K417T, L455F, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K444N, L452R, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, N501Y, L517I",Wild type,GISAID,Wild type,X,X,X
"K417T, F456L, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"R408I, L452R, L455F, T478K",Wild type,GISAID,Wild type,X,X,X
"R346K, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"L390F, L452R, T478K, L517F",Wild type,GISAID,Wild type,X,X,X
"K417T, E471Q, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"R408S, L452R, T478K, E484K",Wild type,GISAID,Wild type,X,X,X
"L452R, N460S, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, L517V, H519L",Wild type,GISAID,Wild type,X,X,X
"I434V, L452R, S477I, T478K",Wild type,GISAID,Wild type,X,X,X
"G339S, A352V, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"Q414R, L452R, L455F, T478K",Wild type,GISAID,Wild type,X,X,X
"G339S, Q414R, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"T376I, G446V, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"V367F, G413W, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, L455F, T478K, A522S",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, L455F, T478K",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, T478K, F486S",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, N501I, G502W, V503C, G504W",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, N501K, G502W, V503C, G504C",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, E484K, F490S, N501Y, T523N",Wild type,GISAID,Wild type,X,X,X
"G339D, Q493R, G496S, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"R346K, K417N, E484K, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"P384S, L452M, E484K, G496S, N501Y",Wild type,GISAID,Wild type,X,X,X
"K444E, Y449H, N460K, G485V, N501Y",Wild type,GISAID,Wild type,X,X,X
"R346K, Q409E, Y449N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K444E, Y449H, Y453F, N460K, G485V, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G446S, L452R, T478K, E484A, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, Y453F, S477I, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, S477I, T478K, N501T, G502E, V503Y, G504S",Wild type,GISAID,Wild type,X,X,X
"G446V, Y449H, N460K, G485V, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, E484K, F497S, N501Y",Wild type,GISAID,Wild type,X,X,X
"V445A, Y449H, N460K, E484K, G485V, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, N439K, E484K, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"R346K, K417N, E484K, S494P, N501Y",Wild type,GISAID,Wild type,X,X,X
"R346K, L452R, T478K, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"R346K, D364N, S371F, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, N440K, G446S, S477N",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, N501T, G502E, V503C, G504K",Wild type,GISAID,Wild type,X,X,X
"K444R, L452R, T478K, F490S, N501Y",Wild type,GISAID,Wild type,X,X,X
"N440D, E484K, S494P, N501T, A522S",Wild type,GISAID,Wild type,X,X,X
"N440K, T478K, E484K, Q493E, N501Y",Wild type,GISAID,Wild type,X,X,X
"G446R, L452R, Y453F, T478K, Q493E",Wild type,GISAID,Wild type,X,X,X
"E406Q, K417T, T470N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, S477N, T478K, G496S, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"N440D, T478K, Q493K, S494P, N501Y",Wild type,GISAID,Wild type,X,X,X
"K444N, V445D, G446S, A475T, G476Y, S477R",Wild type,GISAID,Wild type,X,X,X
"K444T, L452R, G476S, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"R346K, Y449H, A475V, T478K, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"T478K, E484A, F486I, S494P, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, N501T, G502E, V503S, G504N",Wild type,GISAID,Wild type,X,X,X
"N440Y, L441S, D442L, K444F, V445F",Wild type,GISAID,Wild type,X,X,X
"K417N, N501Y",Wild type,GISAID,Wild type,X,X,X
"G446V, L452Q, Y453F, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, G446S",Wild type,GISAID,Wild type,X,X,X
"F342L, W353R",Wild type,GISAID,Wild type,X,X,X
"D405G, K417T, Y449S, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, N501T, G502E, V503Y, G504C",Wild type,GISAID,Wild type,X,X,X
"R346K, V367F, N450S, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417N, E484K, N501Y, L517F, A522S",Wild type,GISAID,Wild type,X,X,X
"P384L, K417N, E484K, N501Y, L517F",Wild type,GISAID,Wild type,X,X,X
"N440F, L441I, D442V, S443F, K444I, V445G, L517P",Wild type,GISAID,Wild type,X,X,X
"N439T, L441V, D442F, K444N, V445F",Wild type,GISAID,Wild type,X,X,X
"A348S, K417N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, G446S",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, R509K, V510E, C525W",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, G496S, P507T, L513I",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, Y453F, G476S, T478K",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, G476S, T478K, Q493H",Wild type,GISAID,Wild type,X,X,X
"K417T, D427N, E471Q, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S373P, Q493R, N501Y",Wild type,GISAID,Wild type,X,X,X
"P337H, F338I, A348V, V350I, D364V, S383F, N501T",Wild type,GISAID,Wild type,X,X,X
"L452M, T470P, Q474K, N481K, F490C, L492S, N501Y",Wild type,GISAID,Wild type,X,X,X
"N440K, G446S, S477N, T478K, E484A",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, N440K, G446S",Wild type,GISAID,Wild type,X,X,X
"R346K, G404A, K417N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"P384L, N440K, Y453F, N460K, A475V, E484K",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"R346K, R408S, Y449H, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417N, N440K, G446S, S477N, T478K, E484A",Wild type,GISAID,Wild type,X,X,X
"G339D, K417N, S477N, T478K, G496S",Wild type,GISAID,Wild type,X,X,X
"A352S, R408K, E484K, F490L, S494P",Wild type,GISAID,Wild type,X,X,X
"R403K, L452Q, T478K, E484K, F497S, P499R",Wild type,GISAID,Wild type,X,X,X
"R346T, K417N, V483F, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, S477N, T478K, C480G, E484K",Wild type,GISAID,Wild type,X,X,X
"K417N, T470I, E484K, F490S, N501Y",Wild type,GISAID,Wild type,X,X,X
"V367F, V382L, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"G339D, N440K, G446S, S477N, T478K, E484A",Wild type,GISAID,Wild type,X,X,X
"P384L, K417T, E484K, N501Y, A520S",Wild type,GISAID,Wild type,X,X,X
"R357I, A372T, A475V, T478K, E484K",Wild type,GISAID,Wild type,X,X,X
"E406Q, G446V, L452R, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"D405G, K417T, E484K, F490L, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, E484K, F486I, T500I, N501Y",Wild type,GISAID,Wild type,X,X,X
"R346K, K417N, L452R, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, L452R, T478K, C488W",Wild type,GISAID,Wild type,X,X,X
"D442V, S443L, K444F, V445C, E484Q",Wild type,GISAID,Wild type,X,X,X
"S371P, S375F, K417N, G446S, T478K, G496S, Y505H",Wild type,GISAID,Wild type,X,X,X
"R346K, K417N, K444R, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"N439I, N440Y, L441Y, D442I, S443V, K444F, V445S",Wild type,GISAID,Wild type,X,X,X
"S359N, S383T, D398N, K444N, S459T, Q474H",Wild type,GISAID,Wild type,X,X,X
"G339D, L452R, T478K, G485R, C488W",Wild type,GISAID,Wild type,X,X,X
"S371L, S373P, S375F, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"A352S, K417T, L452R, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, N440K, G446S, S477N",Wild type,GISAID,Wild type,X,X,X
"Y449H, N460K, I472F, G485V, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, L455F, T478K, E484Q, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, G446S, S477N, T478K, E484A, Q493R",Wild type,GISAID,Wild type,X,X,X
"L335S, N354D, A411S, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, N501T, G502E, V503S",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, G485D, L492I, V503G",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, K417N, N440K, G446S, T478K",Wild type,GISAID,Wild type,X,X,X
"K444N, L452R, S477I, T478K, Q493E",Wild type,GISAID,Wild type,X,X,X
"V367F, P384L, K417N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, G446S, S477N, T478K, E484A, Y505H",Wild type,GISAID,Wild type,X,X,X
"R346K, D427H, Y449N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, I434V, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417T, D427N, E484K, N501Y, A520S",Wild type,GISAID,Wild type,X,X,X
"P337S, N354P, S359G, A411S, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, N440K",Wild type,GISAID,Wild type,X,X,X
"K417T, D427N, P463S, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"K424R, V445A, L452R, L455S, F464C, T478K",Wild type,GISAID,Wild type,X,X,X
"R346S, N394S, Y449N, E484K, F490S, N501Y",Wild type,GISAID,Wild type,X,X,X
"S371P, S477N, T478K, G496S, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, G446S",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, S477I, T478K, Q493K",Wild type,GISAID,Wild type,X,X,X
"K417T, A475V, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"I434V, K444N, L452R, G476S, T478K, F490S",Wild type,GISAID,Wild type,X,X,X
"G431D, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"W353L, S366F, I402T, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"N440K, L441H, D442V, S443F, K444L, V445D",Wild type,GISAID,Wild type,X,X,X
"R346K, Y449N, G476S, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"N439I, N440I, L441Y, D442V, S443C, K444N, E484Q",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, N501T, G502R, V503T, G504Q",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, F490Y, N501Y, L517F",Wild type,GISAID,Wild type,X,X,X
"N439K, N440F, L441N, D442F, S443F, K444L, V445D",Wild type,GISAID,Wild type,X,X,X
"R346I, L452R, T478K, E484Q, P499R",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"V350G, K356N, Y365N, S373A, Y380N",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, E484Q, E516Q, A522V",Wild type,GISAID,Wild type,X,X,X
"S371P, K417N, S477N, T478K, E484A, G496S",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"N440T, L441R, D442Y, S443F, V445A",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, Y453F, T478K, Q493E",Wild type,GISAID,Wild type,X,X,X
"K417T, D427N, V483F, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, T478K, E484Q, N501T",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, R509K, V511I, V512R",Wild type,GISAID,Wild type,X,X,X
"L425F, P426C, D427C, D428R, F429L, T430M",Wild type,GISAID,Wild type,X,X,X
"G339D, N440K, G446S, S477N, T478K, E484A, Q493R",Wild type,GISAID,Wild type,X,X,X
"N354D, K417T, S477N, E484K, Q493K, N501T",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, V503G, V511I, A522T",Wild type,GISAID,Wild type,X,X,X
"V445A, L452R, G476D, S477G, T478K",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"A348S, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"V367F, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"A372V, P384S, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, N501T, G502E, V503F",Wild type,GISAID,Wild type,X,X,X
"V367L, V382L, L452R, T478K, N501S",Wild type,GISAID,Wild type,X,X,X
"K444N, L452R, Y453F, T478K, Y489H",Wild type,GISAID,Wild type,X,X,X
"I402N, R403P, G404H, D405E, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, N440K",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, A522P, C525W",Wild type,GISAID,Wild type,X,X,X
"K417T, D427N, T470I, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"N439I, L441F, D442E, S443F, K444Y",Wild type,GISAID,Wild type,X,X,X
"D427E, L452R, T478K, R509K, V511I",Wild type,GISAID,Wild type,X,X,X
"V367L, V382L, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"R408T, A411H, G416R, A419T, C432F, V433G, N439K",Wild type,GISAID,Wild type,X,X,X
"P384L, K417N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"N354K, E406Q, K417T, V445A, E484K, S494P, N501Y",Wild type,GISAID,Wild type,X,X,X
"S383Y, N439K, N501K, V503L, G504E",Wild type,GISAID,Wild type,X,X,X
"Y365S, L368Q, S371T, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"L387I, I418N, L425V, C480G, F497L",Wild type,GISAID,Wild type,X,X,X
"G446S, L452R, T478K, E484A, F490S, Q493R",Wild type,GISAID,Wild type,X,X,X
"V367F, T393A, G446V, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"A344S, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"V445A, L452R, G476D, T478K, Q493E",Wild type,GISAID,Wild type,X,X,X
"V382L, V401L, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"G339D, K417N, S477N, T478K, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, N440K, G446S",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, P479S, A522V",Wild type,GISAID,Wild type,X,X,X
"G339D, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"V367F, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"T385I, L452R, T478K, E484Q, P499R",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, Y453F, T478K, E484Q, S494L",Wild type,GISAID,Wild type,X,X,X
"N440S, D442F, S443Y, K444I, V445Y, L452R",Wild type,GISAID,Wild type,X,X,X
"V367L, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, E484Q, G485V, E516Q",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, Y453H, G476S, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, G502C, V503A, G504S",Wild type,GISAID,Wild type,X,X,X
"G339D, K417N, N440K, G446S, T478K, G496S",Wild type,GISAID,Wild type,X,X,X
"K444R, G446V, L452R, T478K, V503G, G504V",Wild type,GISAID,Wild type,X,X,X
"K417T, K444N, E484K, N501Y, A522V",Wild type,GISAID,Wild type,X,X,X
"V445A, L452R, G476D, T478K, Q493L",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, G502D, V503G, G504D",Wild type,GISAID,Wild type,X,X,X
"K444N, L452R, Y453F, G476S, T478K",Wild type,GISAID,Wild type,X,X,X
"V367F, K417T, D427Y, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"E406Q, G446V, L452R, Y453F, T478K",Wild type,GISAID,Wild type,X,X,X
"K356R, R357G, N360Y, C361F, N439K",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371P, S375F, K417N, N440K, G446S",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, K417N, S477N, T478K, G496S",Wild type,GISAID,Wild type,X,X,X
"K417T, K444N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, E484Q, S494P, Y508H",Wild type,GISAID,Wild type,X,X,X
"P384L, K417T, Y449S, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"N440I, L441I, S443C, K444F, V445I, G446A, G447C",Wild type,GISAID,Wild type,X,X,X
"T478K, N501T, G502Y, V503T, G504Q",Wild type,GISAID,Wild type,X,X,X
"T393N, R408K, L452R, T478K, Y508N",Wild type,GISAID,Wild type,X,X,X
"W436C, E484K, P507Q, A522Q",Wild type,GISAID,Wild type,X,X,X
"L452R, R457S, N460K, T478K, E484K",Wild type,GISAID,Wild type,X,X,X
"S371F, K417T, E484K, F490S, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452Q, A475V, E484K, P499R, N501T",Wild type,GISAID,Wild type,X,X,X
"N360D, T393I, R408T, Q409H, D467Y, E484K",Wild type,GISAID,Wild type,X,X,X
"G339D, N440K, G446S, S477N, T478K, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, K417N, N440K, G446S, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, R509K, V510G",Wild type,GISAID,Wild type,X,X,X
"N343K, A344D, K417T, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"N354I, K356R, I358F, S359C, N360Y, A363S, N439K",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, Y453F, G476D, T478K",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, Y453F, S477N, T478K",Wild type,GISAID,Wild type,X,X,X
"E340K, P426L, V433A, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, R509K",Wild type,GISAID,Wild type,X,X,X
"K417T, E484K, N501Y, S514F",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, Y453F, T478K, E484K",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F",Wild type,GISAID,Wild type,X,X,X
"L335V, S366T, K417N, L452R, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"G339D, S371F, K417N, S477N, T478K, G496S, Y505H",Wild type,GISAID,Wild type,X,X,X
"D427G, G446V, L452R, G476S, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, S477I, T478K, Q493R",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, L455F, F456V, G476S, T478K",Wild type,GISAID,Wild type,X,X,X
"V367F, R403K, G446S, N481T, E484K, G485A",Wild type,GISAID,Wild type,X,X,X
"I468F, C480W, C488W, V503L, Q506P",Wild type,GISAID,Wild type,X,X,X
"S373P, K417T, K444N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"N439K, L441E, D442F, S443F, K444F",Wild type,GISAID,Wild type,X,X,X
"K417T, D427N, A475S, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"F342L, D405E, R454K, S459P, N460K",Wild type,GISAID,Wild type,X,X,X
"V367F, Y369H, S373L, I434V, E484K",Wild type,GISAID,Wild type,X,X,X
"K417T, G446V, L452R, Y453F, S477I, T478K, Y508H",Wild type,GISAID,Wild type,X,X,X
"T385I, G446D, L452R, T478K, E484G",Wild type,GISAID,Wild type,X,X,X
"V367F, G404S, L452R, T478K, G504Y",Wild type,GISAID,Wild type,X,X,X
"I402T, R408K, A411P, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"Y365F, S366P, L368P, Y369S, N370K, S371T",Wild type,GISAID,Wild type,X,X,X
"L517P, P521H, A522S",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, G502S, V503C, G504C",Wild type,GISAID,Wild type,X,X,X
"L368Q, L452R, E465D, R466K, T478K, G482D",Wild type,GISAID,Wild type,X,X,X
"A348S, L452R, T478K, E484Q, P499R",Wild type,GISAID,Wild type,X,X,X
"V407I, R408T, G413R, D427N, G431R",Wild type,GISAID,Wild type,X,X,X
"L452R, L455F, R466M, T478K, E484K",Wild type,GISAID,Wild type,X,X,X
"G339D, N440K, G446S, Q493R, G496S",Wild type,GISAID,Wild type,X,X,X
"E340K, E406Q, K444N, L452R, L455F, T478K",Wild type,GISAID,Wild type,X,X,X
"R346T, A372T, I402V, Q498H, H519N",Wild type,GISAID,Wild type,X,X,X
"G446D, L452R, G476S, T478K, Q493E",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, V503G, V510I, V511I",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, Q493R, G496S",Wild type,GISAID,Wild type,X,X,X
"G446S, S477N, T478K, E484A, Q493R, Q498R",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, T478K, E484V, Q498R",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371F, S373P, S375F, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, S477I, T478K, Q493E",Wild type,GISAID,Wild type,X,X,X
"K417M, E484K, Q493R, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417N, L452R, T478K, E484Q, P499R",Wild type,GISAID,Wild type,X,X,X
"V367F, G404V, V407I, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"N440H, L441M, D442I, S443F, K444L",Wild type,GISAID,Wild type,X,X,X
"G339D, K417N, S477N, T478K, G496S, Y505H",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, N501I, G502N, V503G, G504D",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, T478K, Q493E, S514F",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, N501K, G502Q, V503C, G504C",Wild type,GISAID,Wild type,X,X,X
"V407I, G416R, S438T, L441H, V445D, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, L455F, F456V, T478K",Wild type,GISAID,Wild type,X,X,X
"D427E, L452R, T478K, Y508N, H519N",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371F, S373P, K417N, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"G339S, N354H, K356E, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, T478K, E484Q, Y508H",Wild type,GISAID,Wild type,X,X,X
"D398E, F400L, V401I, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"N440Y, L441M, D442F, S443F, K444M",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, T478K, V483A, Y508H",Wild type,GISAID,Wild type,X,X,X
"Y421N, F429I, L452R, F464I, Y473N, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, N501K, G502L, V503C",Wild type,GISAID,Wild type,X,X,X
"V367F, G446V, L452R, T478K, N501T",Wild type,GISAID,Wild type,X,X,X
"L390F, V395F, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, L455F, T478K, E484K, S494P",Wild type,GISAID,Wild type,X,X,X
"K444N, L452R, L455F, T478K, E484V",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, N460I, G476S, T478K",Wild type,GISAID,Wild type,X,X,X
"K444N, L452R, L455F, T478K, S494P",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, Q493E, N501I, A522S",Wild type,GISAID,Wild type,X,X,X
"V367F, W436Y, G446V, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, N501C, G502T, V503T, G504H",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, G502S, V503K, G504L",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, Y453F, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"L452R, T470N, T478K, L517V, H519L",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, K417N, G446S, T478K, E484A, Y505H",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, L455F, S477I, T478K",Wild type,GISAID,Wild type,X,X,X
"N439I, N440R, L441V, D442V, S443F",Wild type,GISAID,Wild type,X,X,X
"N448D, R457S, E484D, F486C, N487D, L492V",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, T478K, F486S, Q493L",Wild type,GISAID,Wild type,X,X,X
"R346S, P384L, E406Q, L455F, E484K, F490S, G504S",Wild type,GISAID,Wild type,X,X,X
"L452R, L455F, T478K, V483F, E484K",Wild type,GISAID,Wild type,X,X,X
"E406Q, G446V, L452R, L455F, T478K",Wild type,GISAID,Wild type,X,X,X
"K444N, L452R, L455F, S477N, T478K, E484K",Wild type,GISAID,Wild type,X,X,X
"K417T, K444R, L455F, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, N501K, G502C, V503E, G504C",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, K417N, G446S, T478K, Y505H",Wild type,GISAID,Wild type,X,X,X
"K417N, G446S, S477N, T478K, E484A, Y505H",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, G476D, T478K, E484Q",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, Y453F, G476S, T478K, S494P",Wild type,GISAID,Wild type,X,X,X
"A372V, E406Q, G446V, L455F, T478K",Wild type,GISAID,Wild type,X,X,X
"K378R, Y380F, G381A, V382L, S477I, G496W, T500I, V512G, L517I, L518V",Wild type,GISAID,Wild type,X,X,X
"G339D, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, L452R, S477N, T478K, E484V, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, L452R, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, L452R, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, L452R, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, T415S, L452R, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, N440K, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, L452R, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"S366P, F374V, S375A, F377L, C379W, F400L, I402S, N439K",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, I418L, L452R, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, W436R, L452R, T478K, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, Q414K, L452R, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, N440K, G446S, S477N, T478K, E484A",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, N440K, G446S, Q493R, G496S, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, N440K, G446S, S477N, T478K",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"T385I, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, Q414R, L452R, T478K, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, L452R, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S375F, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, R346I, S371L, S373P, S375F, L452R, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, P384L, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496I, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, G446S, S477N, T478K, E484A, Q493R",Wild type,GISAID,Wild type,X,X,X
"G339D, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, G496S, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, S373P, S375F, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371F, S373P, S375F, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, L452R, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, V367I, S371L, S373P, S375F, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, G446S, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, G496S, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, N440K, G446S, S477N, T478K, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, L452R, T478K, E484A, Q493R, G496S, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S373P, K417N, G446S, S477N, T478K, E484A, G496S, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S375F, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, G446S, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"V367F, A372T, Y449H, N450D, L452R, S477N, Q493K, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, L452R, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, L368Q, S371F, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, C488S, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"T393I, R408T, Q409H, G413R, Q498E, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, Q493R, G496S, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, K417N, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, L461I, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"N360S, C361N, V362G, Y365D, S366Y, V367A, Y369Q, S371N, S373A, F374S, F377T, C379K, G381E, V382G, S383A, E484K, S494P",Wild type,GISAID,Wild type,X,X,X
"G339D, S371F, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, Q498H, P499R, T500G, N501C, G502L, V503T, G504E",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, N440K, G446S, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"R346T, A372T, I402V, Q493K, Q498H, H519N",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, L452R, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, Y396N, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, N440K, G446S, S477N, T478K, E484A, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, T478K",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"S373P, K417N, G446S, S477N, T478K, E484A, Q493R, G496S, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, E471Q, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K",Wild type,GISAID,Wild type,X,X,X
"S371P, A372E, S373K, F374S, S375A, K378N, C379T, G381K, V382G, S383Y, L452R, T478K, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N",Wild type,GISAID,Wild type,X,X,X
"G404C, L452R, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, P384L, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, N440K, T478K, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"L387F, N388Y, D389G, L390V, C391S, F392P, N394K, V395L, Y396N, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, L452R, T478K, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, L452R, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, G446S, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"I402N, N448K, R457S, F464L, D467K, S469Q, T470N, I472N",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, L452R, T478K, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, A522V",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, L452R, T478K, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, G446S, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, G446S, S477N, T478K, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, S477N, T478K, E484A, Q493R, G496S, Q498R",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, L452R, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, G446S, S477N, T478K, E484A",Wild type,GISAID,Wild type,X,X,X
"S371F, K417N, G446S, S477N, T478K, E484A, Q493R, G496S, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G446S, L452R, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, P384S, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346T, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"N440Y, L441V, D442F, S443F, V511Q, V512P, L513T, S514N, F515G, E516V, L517G, H519Q",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, N440K, G446S, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S",Wild type,GISAID,Wild type,X,X,X
"G339D, L452R, T478K, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, A520S",Wild type,GISAID,Wild type,X,X,X
"G339D, L452R, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, L452R, T478K, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G446S, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, T478K",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"N440K, G446S, L452R, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"A348T, D427A, S438Y, N439K, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, G446S, S477N, T478K, E484A, Q493R, G496S, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, K417N, N440K, G446S, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, V445A, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"F347L, S349C, Y351W, A352G, N354D, K356W, R357C, I358F, S359F, N360F, C361F, V362F, A363V, N439K",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S375F, K417N, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"T345A, F347L, N394K, G413T, T415N, G416R, N439K",Wild type,GISAID,Wild type,X,X,X
"N370K, S371Y, A372K, F374A, F377S, Y380K, V382E, S383A, K417N, E484K, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, Q493R",Wild type,GISAID,Wild type,X,X,X
"C361Y, V362D, S366Y, S371Y, S375Y, K378N, C379F, G404D, N439K",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, N440K, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339F, V341I, N354H, R357K, S359N, N360T, S371P, S375P, Y380W, L390P, N394K",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477D, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484V, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, K417N, S477N, T478K, E484A, Q493R, G496S, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, L452R, L455F, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, G431D, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, T478K, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, T478K, Q493R, G496S, Q498R, N501Y",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, S477N, T478K, E484A, Q493R, G496S",Wild type,GISAID,Wild type,X,X,X
"C336G, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, G496S, Q498R, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, Q493R, G496S, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"T393F, V395F, Y396I, D398N, S399Y, V401L, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, G476S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"K356R, R357G, I358F, S359C, N360F, C361F, V362F, A363G, N439K",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, A475V, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, P384S, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G413W, G416R, L452R, N501K, P507K, A520T",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, N440K, G446S, S477N, T478K, E484A, Q493R, G496S",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, L452R, T478K, N501Y",Wild type,GISAID,Wild type,X,X,X
"G446S, L452R, S477N, T478K, E484A, Q493R, G496S, Q498R",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, Q493R, G496S, Q498R",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, I472M, S477N, T478K, E484A, Q493R, G496S",Wild type,GISAID,Wild type,X,X,X
"G339D, T345I, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371P, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R",Wild type,GISAID,Wild type,X,X,X
"G339D, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, L452R, T478K",Wild type,GISAID,Wild type,X,X,X
"G446V, L452R, Y453F, L455F, S477N, T478K, E516Q",Wild type,GISAID,Wild type,X,X,X
"G339D, Y365S, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, Q498H, P499H, T500R, N501L, G502P, V503I, G504E",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371P, K417N, G446S, L452R, S477N, T478K, G496S",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, K417N, G446S, S477N, T478K, E484A, G496S, Y505H",Wild type,GISAID,Wild type,X,X,X
"A352G, N354I, K356G, R357G, I358F, S359F, N360Y, A363Y, N439K",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, G446S, S477N, T478K, E484A, Q493R, G496S",Wild type,GISAID,Wild type,X,X,X
"N343H, L387I, I418N, L425V, E471G, C480G",Wild type,GISAID,Wild type,X,X,X
"L335F, G339V, W353L, V382L, L455F, G476V, T478K, E484A, G496V",Wild type,GISAID,Wild type,X,X,X
"G339D, S373P, N440K, G446S, S477N, T478K, E484A, Q493R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, N440K, G446S, Q493R, G496S, Q498R",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, K417N, N440K, G446S, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, T478K, Y505H",Wild type,GISAID,Wild type,X,X,X
"S373P, K417N, G446S, S477N, T478K, Q493R, G496S, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, K417N, G446S, S477N, T478K, Q493R, G496S, Y505H",Wild type,GISAID,Wild type,X,X,X
"P463L, T500I, N501R, R509K, V511E, S514P, H519I, P521Q, A522P, T523P",Wild type,GISAID,Wild type,X,X,X
"G339D, N440K, G446S, S477N, T478K, E484A, Q493R, G496S",Wild type,GISAID,Wild type,X,X,X
"L452R, T478K, Q498R, P499Q, T500E, N501P, G502A, V503S, G504F",Wild type,GISAID,Wild type,X,X,X
"R346S, K417T, V445A, L452Q, N460K, E484A, F486L, Q498Y, N501T, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, K417N, S477N, T478K, E484A, Q493R, G496S, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, K417N, G446S, S477N, T478K, E484A, Q493R, G496S, Y505H",Wild type,GISAID,Wild type,X,X,X
"R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S",Wild type,GISAID,Wild type,X,X,X
"G339D, S371P, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, S371P, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Y505H",Wild type,GISAID,Wild type,X,X,X
"S371L, K417N, S477N, T478K, E484A, Q493R, G496S, Y505H",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S",Wild type,GISAID,Wild type,X,X,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R",Wild type,GISAID,Wild type,X,X,X
"E465L, D467I, I468F, S469Q, T470L, E471K, I472S, Y473I, Q474M, A475P, G476V, S477A, T478H, P479H, C480V, N481M, G482V, V483L, E484K, G485V, F486L, N487I, C488V, Y489T, P491L, L492Y, Q493N, S494P",Wild type,GISAID,Wild type,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",H34A,"Omicron BA.1 Variant, WHO",Chan et al. (2020),X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",L79I,"Omicron BA.1 Variant, WHO",Chan et al. (2020),X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",L79T,"Omicron BA.1 Variant, WHO",Chan et al. (2020),X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",L79V,"Omicron BA.1 Variant, WHO",Chan et al. (2020),X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",L79W,"Omicron BA.1 Variant, WHO",Chan et al. (2020),X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",L79Y,"Omicron BA.1 Variant, WHO",Chan et al. (2020),X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",N330F,"Omicron BA.1 Variant, WHO",Chan et al. (2020),X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",N330W,"Omicron BA.1 Variant, WHO",Chan et al. (2020),X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",N330Y,"Omicron BA.1 Variant, WHO",Chan et al. (2020),X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",T92H,"Omicron BA.1 Variant, WHO",Chan et al. (2020),X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H","L79R, Q24E","Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",N330R,"Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",R393E,"Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H","T27Y, L79T, E35D","Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H","T27Y, L79T, K31W","Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H","T27Y, L79T, N330Y, A386L","Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H","T27Y, L79T, N330Y, E35D","Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H","T27Y, L79T, N330Y, K31W","Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H","T27Y, L79T, N330Y, N90E","Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H","T27Y, L79T, N330Y, T92C","Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H","T27Y, L79T, N330Y, T92C, E35D","Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H","T27Y, L79T, N330Y, T92S","Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H","T27Y, L79T, N90E","Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H","T27Y, L79T, T92C","Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H","T27Y, L79T, T92C, E35D","Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H","T27Y, L79T, T92S","Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H","T27Y, N330Y, A386L","Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H","T92C, K31W","Omicron BA.1 Variant, WHO",combination,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",D30M,"Omicron BA.1 Variant, WHO",visual inspection,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H","D30M, H34E","Omicron BA.1 Variant, WHO",visual inspection,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",E35D,"Omicron BA.1 Variant, WHO",visual inspection,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",G326E,"Omicron BA.1 Variant, WHO",visual inspection,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",G326N,"Omicron BA.1 Variant, WHO",visual inspection,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",G326Q,"Omicron BA.1 Variant, WHO",visual inspection,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",H34E,"Omicron BA.1 Variant, WHO",visual inspection,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",H34Q,"Omicron BA.1 Variant, WHO",visual inspection,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",K31R,"Omicron BA.1 Variant, WHO",visual inspection,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",K31W,"Omicron BA.1 Variant, WHO",visual inspection,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",K353R,"Omicron BA.1 Variant, WHO",visual inspection,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",T27I,"Omicron BA.1 Variant, WHO",visual inspection,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",T92C,"Omicron BA.1 Variant, WHO",visual inspection,X,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Wild type,"Omicron BA.1, WHO",Wild type,X,X,X
Wild type,H34A,Wild type,Chan et al. (2020),X,X,X
Wild type,L79I,Wild type,Chan et al. (2020),X,X,X
Wild type,L79T,Wild type,Chan et al. (2020),X,X,X
Wild type,L79V,Wild type,Chan et al. (2020),X,X,X
Wild type,L79W,Wild type,Chan et al. (2020),X,X,X
Wild type,L79Y,Wild type,Chan et al. (2020),X,X,X
Wild type,N330F,Wild type,Chan et al. (2020),X,X,X
Wild type,N330W,Wild type,Chan et al. (2020),X,X,X
Wild type,N330Y,Wild type,Chan et al. (2020),X,X,X
Wild type,T92H,Wild type,Chan et al. (2020),X,X,X
Wild type,"L79R, Q24E",Wild type,combination,X,X,X
Wild type,N330R,Wild type,combination,X,X,X
Wild type,R393E,Wild type,combination,X,X,X
Wild type,"T27Y, L79T, E35D",Wild type,combination,X,X,X
Wild type,"T27Y, L79T, K31W",Wild type,combination,X,X,X
Wild type,"T27Y, L79T, N330Y, A386L",Wild type,combination,X,X,X
Wild type,"T27Y, L79T, N330Y,E35D",Wild type,combination,X,X,X
Wild type,"T27Y, L79T, N330Y,K31W",Wild type,combination,X,X,X
Wild type,"T27Y, L79T, N330Y,N90E",Wild type,combination,X,X,X
Wild type,"T27Y, L79T, N330Y,T92C",Wild type,combination,X,X,X
Wild type,"T27Y, L79T, N330Y,T92C,E35D",Wild type,combination,X,X,X
Wild type,"T27Y, L79T, N330Y,T92S",Wild type,combination,X,X,X
Wild type,"T27Y, L79T, N90E",Wild type,combination,X,X,X
Wild type,"T27Y, L79T, T92C",Wild type,combination,X,X,X
Wild type,"T27Y, L79T, T92C, E35D",Wild type,combination,X,X,X
Wild type,"T27Y, L79T, T92S",Wild type,combination,X,X,X
Wild type,"T27Y,N330Y, A386L",Wild type,combination,X,X,X
Wild type,"T92C, K31W",Wild type,combination,X,X,X
Wild type,D30M,Wild type,visual inspection,X,X,X
Wild type,"D30M, H34E",Wild type,visual inspection,X,X,X
Wild type,E35D,Wild type,visual inspection,X,X,X
Wild type,G326E,Wild type,visual inspection,X,X,X
Wild type,G326N,Wild type,visual inspection,X,X,X
Wild type,G326Q,Wild type,visual inspection,X,X,X
Wild type,H34E,Wild type,visual inspection,X,X,X
Wild type,H34Q,Wild type,visual inspection,X,X,X
Wild type,K31R,Wild type,visual inspection,X,X,X
Wild type,K31W,Wild type,visual inspection,X,X,X
Wild type,K353R,Wild type,visual inspection,X,X,X
Wild type,T27I,Wild type,visual inspection,X,X,X
Wild type,T92C,Wild type,visual inspection,X,X,X
Wild type,Wild type,Wild type,Wild type,X,X,X
"I358F, S477R, E484K, Q498R, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, N460K, E484K, S494P, Q498R, N501Y, A520G",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, N460K, E484K, Q498R, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, S477N, Q498R, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, N460K, T478S, E484K, Q498R, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, T470M, E484K, Q498R, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, N460K, S477N, E484K, Q498R, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, E484K, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, T478I, Q498R, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, K417N, E484K, Q498R, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, Q498R, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, K417T, T470M, E484K, Q498R, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, N448S, E484K, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, I468T, N481Y, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, G446R, E484K, F490Y, Q498R, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, S477N, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, N448S, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, I468V, E484K, Q498R, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, N448S, E484K, F490S, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, V483E, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, K417T, E484K, Q498R, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"I358F, I468T, E484K, N501Y",Wild type,Zahradnik et al. (2021),Wild type,X,X,X
E484R,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
E484K,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
N439K,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
A475V,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
S477R,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
T478K,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
N460K,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
N501T,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
I358F,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
T470M,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
S494P,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
S477N,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
T478I,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
V445K,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
K417T,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
K417N,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
Q498R,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
I468T,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
G446V,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
N501Y,Wild type,Zahradnik et al. (2021),Wild type,X,X,X
"R346K, E484K, N501Y, A522S",Wild type,GISAID,Wild type,,X,X
"T478K, Q493K, S494P, N501Y",Wild type,GISAID,Wild type,,X,X
"T478K, E484K, G496S, N501Y",Wild type,GISAID,Wild type,,X,X
"L452R, S477I, T478K, N501Y",Wild type,GISAID,Wild type,,X,X
"R346K, N450D, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"N501Y, L518Q, H519N, P521L",Wild type,GISAID,Wild type,,X,X
"R346K, L441I, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"R346K, E484K, N501Y, Y508H",Wild type,GISAID,Wild type,,X,X
"R346K, Y449H, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"R346K, E484K, N501Y, G504D",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, P479S, Q493H",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, V483F, N501Y",Wild type,GISAID,Wild type,,X,X
"K417T, P426S, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"R346K, V367F, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"G446S, L452R, T478K, A522S",Wild type,GISAID,Wild type,,X,X
"N440K, Y449H, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"K417T, V483I, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"L452R, S477I, T478K, A522P",Wild type,GISAID,Wild type,,X,X
"K417N, E484K, N501Y, L517F",Wild type,GISAID,Wild type,,X,X
"K417T, A475T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, E484Q, H519L",Wild type,GISAID,Wild type,,X,X
"R346K, R357K, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"A348S, L452R, T478K, E484Q",Wild type,GISAID,Wild type,,X,X
"G446V, L452R, T478K, E484K",Wild type,GISAID,Wild type,,X,X
"L452R, A475S, S477I, T478K",Wild type,GISAID,Wild type,,X,X
"K417R, A475V, T478K, N501Y",Wild type,GISAID,Wild type,,X,X
"E406Q, K417N, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"N370S, L452R, T478K, V483F",Wild type,GISAID,Wild type,,X,X
"L452R, T470I, T478K, N501Y",Wild type,GISAID,Wild type,,X,X
"G446S, L452R, T478K, N501Y",Wild type,GISAID,Wild type,,X,X
"E406Q, L452R, L455F, N501Y",Wild type,GISAID,Wild type,,X,X
"N354D, K417N, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"V362F, K417N, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"Q414R, K417N, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"N354D, L452R, T478K, E516Q",Wild type,GISAID,Wild type,,X,X
"L452R, S477I, T478K, P499S",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, V483F, A522V",Wild type,GISAID,Wild type,,X,X
"K417T, I468L, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"K417T, Y453H, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"N370S, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"K417N, L425V, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"K417T, E484K, N501Y, T523P",Wild type,GISAID,Wild type,,X,X
"A363V, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"L452R, G476S, T478K, Q493H",Wild type,GISAID,Wild type,,X,X
"R346K, E484K, N501Y, A522P",Wild type,GISAID,Wild type,,X,X
"K417N, V483F, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"L452R, Q474H, A475S, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, S477I, T478K, A522V",Wild type,GISAID,Wild type,,X,X
"A372T, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"R346K, L452M, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"G339D, K417N, S477N, T478K",Wild type,GISAID,Wild type,,X,X
"S373L, L452R, S477I, T478K",Wild type,GISAID,Wild type,,X,X
"G413W, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"T376I, K417N, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"V401L, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"T345S, R346K, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"K417T, D427A, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"G446S, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"T385I, L452R, T478K, E484Q",Wild type,GISAID,Wild type,,X,X
"L452R, T470I, E471Q, T478K",Wild type,GISAID,Wild type,,X,X
"R346K, A475V, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, E484Q, S494P",Wild type,GISAID,Wild type,,X,X
"Q409K, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, E484Q, A520S",Wild type,GISAID,Wild type,,X,X
"A344S, A348S, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"K417N, L452R, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"K417T, E484K, G485D, N501Y",Wild type,GISAID,Wild type,,X,X
"K417T, E484K, F490S, N501Y",Wild type,GISAID,Wild type,,X,X
"E406Q, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"R346K, V445I, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"S359T, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"V367L, L452R, T478K, L517F",Wild type,GISAID,Wild type,,X,X
"A344V, K417N, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"F338L, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"G339V, K417N, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"N394D, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"S359N, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"N370S, L452R, T478K, V483I",Wild type,GISAID,Wild type,,X,X
"A344S, L452R, T478K, E484A",Wild type,GISAID,Wild type,,X,X
"G339D, L452R, T478K, S514Y",Wild type,GISAID,Wild type,,X,X
"T385I, L452R, T478K, V483F",Wild type,GISAID,Wild type,,X,X
"L452R, F464L, T478K, A520S",Wild type,GISAID,Wild type,,X,X
"G446D, L452R, T478K, E484Q",Wild type,GISAID,Wild type,,X,X
"K417T, E484K, N501Y, P507S",Wild type,GISAID,Wild type,,X,X
"K417N, E484K, F490Y, N501Y",Wild type,GISAID,Wild type,,X,X
"V367F, L452R, T478K, L513F",Wild type,GISAID,Wild type,,X,X
"K417N, L452R, T478K, N501T",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, H519Q",Wild type,GISAID,Wild type,,X,X
"V362F, A411S, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, S477I, T478K, E484A",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, G485A, L518I",Wild type,GISAID,Wild type,,X,X
"R346K, E484K, N501Y, V503I",Wild type,GISAID,Wild type,,X,X
"G446S, T478K, G496S, Q498R",Wild type,GISAID,Wild type,,X,X
"R346T, L452R, T478K, E484Q",Wild type,GISAID,Wild type,,X,X
"V382L, L452R, T478K, E484Q",Wild type,GISAID,Wild type,,X,X
"K417N, N440T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, V483F, A520S",Wild type,GISAID,Wild type,,X,X
"N440Y, G447V, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"L390F, K417N, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"G446V, L452R, T478K, Q493K",Wild type,GISAID,Wild type,,X,X
"L452R, S477I, T478K, S514F",Wild type,GISAID,Wild type,,X,X
"V341I, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"A411S, L452R, S477N, T478K",Wild type,GISAID,Wild type,,X,X
"A344S, L452R, S459F, T478K",Wild type,GISAID,Wild type,,X,X
"D428E, L452R, T478K, P479S",Wild type,GISAID,Wild type,,X,X
"K417T, E484K, N501Y, H519Q",Wild type,GISAID,Wild type,,X,X
"R403K, I418V, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"A348S, L452R, T478K, S494A",Wild type,GISAID,Wild type,,X,X
"T333I, L452R, S459F, T478K",Wild type,GISAID,Wild type,,X,X
"L335F, A348S, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"K417N, T478I, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, V483F, E484Q",Wild type,GISAID,Wild type,,X,X
"L452R, S477N, T478K, P499L",Wild type,GISAID,Wild type,,X,X
"K417T, I468S, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"Y380F, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"G381R, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"L335V, L452R, L461I, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, P479L, A522V",Wild type,GISAID,Wild type,,X,X
"R346G, L452R, Q474E, T478K",Wild type,GISAID,Wild type,,X,X
"K417T, E484K, Y489H, N501Y",Wild type,GISAID,Wild type,,X,X
"L452R, S477I, T478K, E484Q",Wild type,GISAID,Wild type,,X,X
"T333I, K417N, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"N354D, L452R, T478K, A522S",Wild type,GISAID,Wild type,,X,X
"R346K, L452R, T478K, G482S",Wild type,GISAID,Wild type,,X,X
"L452R, Q474H, T478K, V483I",Wild type,GISAID,Wild type,,X,X
"N354K, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"V367A, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"K417N, L452R, S477I, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, F490S",Wild type,GISAID,Wild type,,X,X
"S359I, V367F, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"Y351F, L452R, S477I, T478K",Wild type,GISAID,Wild type,,X,X
"G339D, G446V, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"G339D, L452R, T478K, V483F",Wild type,GISAID,Wild type,,X,X
"N370S, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"D428G, L452R, S477N, T478K",Wild type,GISAID,Wild type,,X,X
"V362F, L452R, T478K, P479S",Wild type,GISAID,Wild type,,X,X
"L452R, N460S, A475V, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, G482V, A520S",Wild type,GISAID,Wild type,,X,X
"G339D, R346K, N440K, G446S",Wild type,GISAID,Wild type,,X,X
"A411V, K417N, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"K417T, V433I, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"S373P, Y451H, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, F490L, S494P",Wild type,GISAID,Wild type,,X,X
"T345I, A372S, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"K417T, N448D, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"V395I, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, F490L, A522P",Wild type,GISAID,Wild type,,X,X
"A348S, N394S, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"K417N, L452R, T478K, N501Y",Wild type,GISAID,Wild type,,X,X
"R346G, A435S, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"R346K, Y451H, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"Q414R, L452R, T478K, V483F",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, S494P, A522S",Wild type,GISAID,Wild type,,X,X
"K417N, E484K, F490S, N501T",Wild type,GISAID,Wild type,,X,X
"T385I, I418V, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"K378N, L452R, T478K, E484K",Wild type,GISAID,Wild type,,X,X
"V395F, L452R, T478K, T523A",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, E484Q, G504N",Wild type,GISAID,Wild type,,X,X
"T415N, L452R, T478K, E484Q",Wild type,GISAID,Wild type,,X,X
"L452R, K458N, G476S, T478K",Wild type,GISAID,Wild type,,X,X
"E484K, F490S, N501T, A520S",Wild type,GISAID,Wild type,,X,X
"A435S, G446V, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"V367I, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"A348S, A419S, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"V382L, P384L, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"V362F, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, S514F, A520S",Wild type,GISAID,Wild type,,X,X
"R346K, R355S, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"Q414K, L452R, T478K, A520S",Wild type,GISAID,Wild type,,X,X
"V367A, I434M, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"Q414K, L452R, E471Q, T478K",Wild type,GISAID,Wild type,,X,X
"L425V, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"K417T, E484K, F490L, N501Y",Wild type,GISAID,Wild type,,X,X
"L452R, S459F, T478K, A520S",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, P479H, G504D",Wild type,GISAID,Wild type,,X,X
"V367F, V407I, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, S459F, T478K, P479S",Wild type,GISAID,Wild type,,X,X
"K417T, E484K, P491S, N501Y",Wild type,GISAID,Wild type,,X,X
"R408I, L452R, T478K, V483F",Wild type,GISAID,Wild type,,X,X
"L452R, S477G, T478K, E484Q",Wild type,GISAID,Wild type,,X,X
"I434V, G446V, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"V433I, L452R, T478K, A522S",Wild type,GISAID,Wild type,,X,X
"N354K, L452R, T478K, P479S",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, E484Q, G485S",Wild type,GISAID,Wild type,,X,X
"L441F, K444N, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, E484Q, Y508H",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, P479S",Wild type,GISAID,Wild type,,X,X
"S373L, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, P479L, E484Q",Wild type,GISAID,Wild type,,X,X
"T393A, K417N, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"A397V, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"V445I, L452R, T478K, E484Q",Wild type,GISAID,Wild type,,X,X
"K444N, L452R, T478K, Q498R",Wild type,GISAID,Wild type,,X,X
"L452R, N460Y, T478K, S494P",Wild type,GISAID,Wild type,,X,X
"G339D, R346K, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, G485V, Y508H",Wild type,GISAID,Wild type,,X,X
"K417N, L452R, T478K, T523N",Wild type,GISAID,Wild type,,X,X
"F374L, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"E340K, A348S, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, L518I",Wild type,GISAID,Wild type,,X,X
"L425V, L452R, T478K, A522V",Wild type,GISAID,Wild type,,X,X
"G446V, L452R, T478K, S494L",Wild type,GISAID,Wild type,,X,X
"K417T, E484K, N501Y, L517V",Wild type,GISAID,Wild type,,X,X
"N354T, G446V, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, V512I, A522P",Wild type,GISAID,Wild type,,X,X
"I434V, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, N460Y, T478K",Wild type,GISAID,Wild type,,X,X
"G446V, L452R, T478K, A522S",Wild type,GISAID,Wild type,,X,X
"A348S, G404A, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"G446V, L452R, T478K, A520S",Wild type,GISAID,Wild type,,X,X
"G339D, L452R, S477I, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, N460S, T478K, E484K",Wild type,GISAID,Wild type,,X,X
"L452R, A475V, T478K, A522S",Wild type,GISAID,Wild type,,X,X
"G446V, L452R, T478K, P479S",Wild type,GISAID,Wild type,,X,X
"P337L, V367F, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"R408I, A419S, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"R408I, L452R, T478K, Q493T",Wild type,GISAID,Wild type,,X,X
"K417N, T430I, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, P463S, S477G, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, P479S, S494L",Wild type,GISAID,Wild type,,X,X
"L335F, L452R, T478K, E484Q",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, A520V, A522V",Wild type,GISAID,Wild type,,X,X
"R346T, I410V, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"R346K, L455F, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"G446V, L452R, T478K, Y489H",Wild type,GISAID,Wild type,,X,X
"N354K, L452R, T478K, A522V",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, A522S",Wild type,GISAID,Wild type,,X,X
"G413V, L452R, T470N, T478K",Wild type,GISAID,Wild type,,X,X
"R346K, P384L, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"Q414L, L452R, T478K, P479S",Wild type,GISAID,Wild type,,X,X
"V367F, K417N, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"K444N, L452R, G476S, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, F490L",Wild type,GISAID,Wild type,,X,X
"S371A, L452R, T478K, E484K",Wild type,GISAID,Wild type,,X,X
"L452R, L455F, T478K, P479S",Wild type,GISAID,Wild type,,X,X
"R346I, Q414H, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"V445A, L452R, G476D, T478K",Wild type,GISAID,Wild type,,X,X
"Y351F, L452R, N460Y, T478K",Wild type,GISAID,Wild type,,X,X
"G446V, L452R, T478K, E484A",Wild type,GISAID,Wild type,,X,X
"N354K, L452R, T478K, V483I",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, P499L, A522V",Wild type,GISAID,Wild type,,X,X
"E340A, L452R, T478K, E516Q",Wild type,GISAID,Wild type,,X,X
"A348S, L452R, G476S, T478K",Wild type,GISAID,Wild type,,X,X
"G446V, L452R, S459F, T478K",Wild type,GISAID,Wild type,,X,X
"A344S, K417N, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"K356E, A372T, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, P463S, G476S, T478K",Wild type,GISAID,Wild type,,X,X
"G446V, L452R, E471G, T478K",Wild type,GISAID,Wild type,,X,X
"A411S, K417N, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"E406Q, G446V, L452R, L455F",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, S494P",Wild type,GISAID,Wild type,,X,X
"V382L, K417N, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"R403K, G446V, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"T385I, L452R, G476S, T478K",Wild type,GISAID,Wild type,,X,X
"P337L, N354T, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"N370S, G446V, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"G339D, S371P, K417N, T478K",Wild type,GISAID,Wild type,,X,X
"A352V, K417N, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"G446V, L452R, Y473F, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, L455F, T478K, V483G",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, E484Q, N501I",Wild type,GISAID,Wild type,,X,X
"L335W, L452R, T478K, H519Y",Wild type,GISAID,Wild type,,X,X
"R408I, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"N440S, G446V, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"G446V, L452R, T478K, V483F",Wild type,GISAID,Wild type,,X,X
"V407I, K417N, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"K417N, N439K, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, E484A, N501S",Wild type,GISAID,Wild type,,X,X
"L452R, L455F, T478K, E484Q",Wild type,GISAID,Wild type,,X,X
"V367F, L452R, L455F, T478K",Wild type,GISAID,Wild type,,X,X
"R346S, G446V, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"L452R, L455F, T478K, E484V",Wild type,GISAID,Wild type,,X,X
"L452R, L455F, T478K, V483F",Wild type,GISAID,Wild type,,X,X
"R346K, I468T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"N354S, L452R, T478K, Y508H",Wild type,GISAID,Wild type,,X,X
"K417N, E484K, N501Y, V503F",Wild type,GISAID,Wild type,,X,X
"P384S, L452R, T478K, N501S",Wild type,GISAID,Wild type,,X,X
"L368I, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"R346K, N481K, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"A344T, L452R, T478K, A522V",Wild type,GISAID,Wild type,,X,X
"G446S, L452R, T478K, E484Q",Wild type,GISAID,Wild type,,X,X
"A344S, N354K, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"N354S, G446V, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"P384S, K417N, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"V367I, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"R346K, S477I, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"K417T, N450D, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"R346K, L452R, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"K417T, E484K, N501Y, H519Y",Wild type,GISAID,Wild type,,X,X
"L452M, S477N, Q493R, N501T",Wild type,GISAID,Wild type,,X,X
"L452R, S477I, T478K, A522S",Wild type,GISAID,Wild type,,X,X
"D427N, L452R, T478R, E484Q",Wild type,GISAID,Wild type,,X,X
"L452R, S459F, T478K, F490L",Wild type,GISAID,Wild type,,X,X
"N370S, L452R, E471Q, T478K",Wild type,GISAID,Wild type,,X,X
"K417T, E484K, N501Y, V503A",Wild type,GISAID,Wild type,,X,X
"K417N, Y473F, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"L335V, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"A435S, L452R, G476S, T478K",Wild type,GISAID,Wild type,,X,X
"A352S, I434V, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"P384L, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"K356N, L452R, S459F, T478K",Wild type,GISAID,Wild type,,X,X
"K417N, E484K, G496S, N501Y",Wild type,GISAID,Wild type,,X,X
"L452R, S477I, T478K, A520S",Wild type,GISAID,Wild type,,X,X
"R346K, E484K, S494P, N501Y",Wild type,GISAID,Wild type,,X,X
"R346K, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"V382L, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"K417N, N440K, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"P426S, L452R, S477N, T478K",Wild type,GISAID,Wild type,,X,X
"N354D, K417T, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, E484Q, A522V",Wild type,GISAID,Wild type,,X,X
"K378N, K417N, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"A435T, K444R, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"G446S, L452R, T478K, A522V",Wild type,GISAID,Wild type,,X,X
"K378R, T415N, L452R, T478K",Wild type,GISAID,Wild type,,X,X
"K417T, I472V, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, E484Q, P499R",Wild type,GISAID,Wild type,,X,X
"K417T, N460S, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"G446V, L452R, Y453F, T478K",Wild type,GISAID,Wild type,,X,X
"K417N, L455F, E484K, N501Y",Wild type,GISAID,Wild type,,X,X
"L452R, T478K, E484K, S494P",Wild type,GISAID,Wild type,,X,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S",Wild type,GISAID,Wild type,,X,X
"K417N, E484K, N501Y",Q102Y,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",I21R,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",Q24Y,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",A25Q,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",R273D,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",F28K,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",L29D,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",D30F,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",T324K,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",G326C,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",E329H,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",N330C,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",V343G,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",H345P,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",P346W,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",H34F,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",L351T,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",G354K,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",R357D,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",E35S,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",M366N,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",T371P,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",E37C,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",M383N,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",P389I,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",D38Y,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",R393Y,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",H401F,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",Y41I,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",Q42W,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",Q442I,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",I446P,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",L45G,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",W48K,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",D509F,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",Y50K,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",N51P,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",N63P,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",K68D,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",F72P,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",L79C,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",M82E,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",Y83E,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",P84I,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",V93H,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",Q96F,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",Q98P,"Beta Variant, WHO",Chan et al. (2020),,,X
"K417N, E484K, N501Y",Y41H,"Beta Variant, WHO",visual inspection,,,X
"K417N, E484K, N501Y",Y41Q,"Beta Variant, WHO",visual inspection,,,X
"K417N, E484K, N501Y",Q76M,"Beta Variant, WHO",visual inspection,,,X
"L452R, T478K",Q102Y,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",I21R,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",Q24Y,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",A25Q,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",R273D,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",F28K,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",L29D,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",D30F,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",T324K,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",G326C,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",E329H,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",N330C,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",V343G,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",H345P,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",P346W,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",H34F,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",L351T,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",G354K,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",R357D,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",E35S,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",M366N,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",T371P,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",E37C,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",M383N,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",P389I,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",D38Y,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",R393Y,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",H401F,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",Y41I,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",Q42W,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",Q442I,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",I446P,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",L45G,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",W48K,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",D509F,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",Y50K,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",N51P,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",N63P,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",K68D,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",F72P,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",L79C,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",M82E,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",Y83E,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",P84I,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",V93H,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",Q96F,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",Q98P,"Delta Variant, WHO",Chan et al. (2020),,,X
"L452R, T478K",Y41H,"Delta Variant, WHO",visual inspection,,,X
"L452R, T478K",Y41Q,"Delta Variant, WHO",visual inspection,,,X
"L452R, T478K",Q76M,"Delta Variant, WHO",visual inspection,,,X
"L452R, T478K, P479S, P499R",R273D,GISAID,Chan et al. (2020),,,X
"K417M, G446V, E484Q, N501Y",D509F,GISAID,Chan et al. (2020),,,X
"A372V, E406Q, G446V, L455F, T478K",M383N,GISAID,Chan et al. (2020),,,X
"L452R, T470N, T478K, L517V, H519L",A25Q,GISAID,Chan et al. (2020),,,X
"P384S, L452M, E484K, G496S, N501Y",F72P,GISAID,Chan et al. (2020),,,X
"N440D, E484K, S494P, N501T, A522S",I21R,GISAID,Chan et al. (2020),,,X
"L452R, T478K, N501K, G502C, V503E, G504C",Y41Q,GISAID,Chan et al. (2020),,,X
"L452R, T478K, N501I, G502W, V503C, G504W",N330C,GISAID,Chan et al. (2020),,,X
"N448D, R457S, E484D, F486C, N487D, L492V",Y83E,GISAID,Chan et al. (2020),,,X
"T393F, V395F, Y396I, D398N, S399Y, V401L, L452R, T478K",G354K,GISAID,Chan et al. (2020),,,X
"K378R, Y380F, G381A, V382L, S477I, G496W, T500I, V512G, L517I, L518V",W48K,GISAID,Chan et al. (2020),,,X
"G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R",Q102Y,GISAID,Chan et al. (2020),,,X
"G446V, L452R, T478K, F486S",N330W,GISAID,Chan et al. (2020),,,X
"E465L, D467I, I468F, S469Q, T470L, E471K, I472S, Y473I, Q474M, A475P, G476V, S477A, T478H, P479H, C480V, N481M, G482V, V483L, E484K, G485V, F486L, N487I, C488V, Y489T, P491L, L492Y, Q493N, S494P",L79W,GISAID,Chan et al. (2020),,,X
"A372P, K417T, E484K, N501Y","T27Y, L79T, N330Y, A386L",GISAID,combination,,,X
"R346K, V483F, E484K, N501Y","T27Y, L79T, T92C",GISAID,combination,,,X
"V367F, K417T, D427Y, E484K, N501Y","T27Y, L79T, N330Y, N90E",GISAID,combination,,,X
"K444N, V445D, G446S, A475T, G476Y, S477R","T27Y, L79T, N330Y, K31W",GISAID,combination,,,X
"L452R, T478K, E484K, F490S, N501Y, T523N",N330R,GISAID,combination,,,X
"R346S, P384L, E406Q, L455F, E484K, F490S, G504S","T27Y, L79T, N330Y, T92C, E35D",GISAID,combination,,,X
"K417N, L452R, T478K, P479L","D30M, H34E",GISAID,visual inspection,,,X
"N439I, N440R, L441V, D442V, S443F",K31W,GISAID,visual inspection,,,X
"K356R, R357G, N360Y, C361F, N439K",T27I,GISAID,visual inspection,,,X
"G446V, L452R, Y453F, G476S, T478K, S494P",D30M,GISAID,visual inspection,,,X
"V445A, Y449H, N460K, E484K, G485V, N501Y",K353R,GISAID,visual inspection,,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Q102Y,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",I21R,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Q24Y,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",A25Q,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",R273D,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",F28K,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",L29D,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",D30F,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",T324K,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",G326C,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",E329H,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",N330C,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",V343G,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",H345P,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",P346W,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",H34F,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",L351T,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",G354K,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",R357D,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",E35S,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",M366N,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",T371P,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",E37C,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",M383N,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",P389I,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",D38Y,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",R393Y,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",H401F,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Y41I,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Q42W,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Q442I,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",I446P,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",L45G,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",W48K,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",D509F,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Y50K,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",N51P,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",N63P,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",K68D,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",F72P,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",L79C,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",M82E,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Y83E,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",P84I,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",V93H,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Q96F,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Q98P,"Omicron BA.1 Variant, WHO",Chan et al. (2020),,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Y41H,"Omicron BA.1 Variant, WHO",visual inspection,,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Y41Q,"Omicron BA.1 Variant, WHO",visual inspection,,,X
"G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H",Q76M,"Omicron BA.1 Variant, WHO",visual inspection,,,X
Wild type,Q102Y,Wild type,Chan et al. (2020),,,X
Wild type,I21R,Wild type,Chan et al. (2020),,,X
Wild type,Q24Y,Wild type,Chan et al. (2020),,,X
Wild type,A25Q,Wild type,Chan et al. (2020),,,X
Wild type,R273D,Wild type,Chan et al. (2020),,,X
Wild type,F28K,Wild type,Chan et al. (2020),,,X
Wild type,L29D,Wild type,Chan et al. (2020),,,X
Wild type,D30F,Wild type,Chan et al. (2020),,,X
Wild type,T324K,Wild type,Chan et al. (2020),,,X
Wild type,G326C,Wild type,Chan et al. (2020),,,X
Wild type,E329H,Wild type,Chan et al. (2020),,,X
Wild type,N330C,Wild type,Chan et al. (2020),,,X
Wild type,V343G,Wild type,Chan et al. (2020),,,X
Wild type,H345P,Wild type,Chan et al. (2020),,,X
Wild type,P346W,Wild type,Chan et al. (2020),,,X
Wild type,H34F,Wild type,Chan et al. (2020),,,X
Wild type,L351T,Wild type,Chan et al. (2020),,,X
Wild type,G354K,Wild type,Chan et al. (2020),,,X
Wild type,R357D,Wild type,Chan et al. (2020),,,X
Wild type,E35S,Wild type,Chan et al. (2020),,,X
Wild type,M366N,Wild type,Chan et al. (2020),,,X
Wild type,T371P,Wild type,Chan et al. (2020),,,X
Wild type,E37C,Wild type,Chan et al. (2020),,,X
Wild type,M383N,Wild type,Chan et al. (2020),,,X
Wild type,P389I,Wild type,Chan et al. (2020),,,X
Wild type,D38Y,Wild type,Chan et al. (2020),,,X
Wild type,R393Y,Wild type,Chan et al. (2020),,,X
Wild type,H401F,Wild type,Chan et al. (2020),,,X
Wild type,Y41I,Wild type,Chan et al. (2020),,,X
Wild type,Q42W,Wild type,Chan et al. (2020),,,X
Wild type,Q442I,Wild type,Chan et al. (2020),,,X
Wild type,I446P,Wild type,Chan et al. (2020),,,X
Wild type,L45G,Wild type,Chan et al. (2020),,,X
Wild type,W48K,Wild type,Chan et al. (2020),,,X
Wild type,D509F,Wild type,Chan et al. (2020),,,X
Wild type,Y50K,Wild type,Chan et al. (2020),,,X
Wild type,N51P,Wild type,Chan et al. (2020),,,X
Wild type,N63P,Wild type,Chan et al. (2020),,,X
Wild type,K68D,Wild type,Chan et al. (2020),,,X
Wild type,F72P,Wild type,Chan et al. (2020),,,X
Wild type,L79C,Wild type,Chan et al. (2020),,,X
Wild type,M82E,Wild type,Chan et al. (2020),,,X
Wild type,Y83E,Wild type,Chan et al. (2020),,,X
Wild type,P84I,Wild type,Chan et al. (2020),,,X
Wild type,V93H,Wild type,Chan et al. (2020),,,X
Wild type,Q96F,Wild type,Chan et al. (2020),,,X
Wild type,Q98P,Wild type,Chan et al. (2020),,,X
Wild type,Y41H,Wild type,visual inspection,,,X
Wild type,Y41Q,Wild type,visual inspection,,,X
Wild type,Q76M,Wild type,visual inspection,,,X
"I358F, N460K, E484K, S494P, Q498R, N501Y, A520G",Y41I,Zahradnik et al. (2021),Chan et al. (2020),,,X
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",Wild type,"Omicron BA.1 Variant, WHO",Wild type,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",H34A,"Omicron BA.2 Variant, WHO",Chan et al. (2020),X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",L79I,"Omicron BA.2 Variant, WHO",Chan et al. (2020),X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",L79T,"Omicron BA.2 Variant, WHO",Chan et al. (2020),X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",L79V,"Omicron BA.2 Variant, WHO",Chan et al. (2020),X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",L79W,"Omicron BA.2 Variant, WHO",Chan et al. (2020),X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",L79Y,"Omicron BA.2 Variant, WHO",Chan et al. (2020),X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",N330F,"Omicron BA.2 Variant, WHO",Chan et al. (2020),X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",N330W,"Omicron BA.2 Variant, WHO",Chan et al. (2020),X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",N330Y,"Omicron BA.2 Variant, WHO",Chan et al. (2020),X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",T92H,"Omicron BA.2 Variant, WHO",Chan et al. (2020),X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H","L79R, Q24E","Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",N330R,"Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",R393E,"Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H","T27Y, L79T, E35D","Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H","T27Y, L79T, K31W","Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H","T27Y, L79T, N330Y, A386L","Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H","T27Y, L79T, N330Y, E35D","Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H","T27Y, L79T, N330Y, K31W","Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H","T27Y, L79T, N330Y, N90E","Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H","T27Y, L79T, N330Y, T92C","Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H","T27Y, L79T, N330Y, T92C, E35D","Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H","T27Y, L79T, N330Y, T92S","Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H","T27Y, L79T, N90E","Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H","T27Y, L79T, T92C","Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H","T27Y, L79T, T92C, E35D","Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H","T27Y, L79T, T92S","Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H","T27Y, N330Y, A386L","Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H","T92C, K31W","Omicron BA.2 Variant, WHO",combination,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",D30M,"Omicron BA.2 Variant, WHO",visual inspection,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H","D30M, H34E","Omicron BA.2 Variant, WHO",visual inspection,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",E35D,"Omicron BA.2 Variant, WHO",visual inspection,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",G326E,"Omicron BA.2 Variant, WHO",visual inspection,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",G326N,"Omicron BA.2 Variant, WHO",visual inspection,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",G326Q,"Omicron BA.2 Variant, WHO",visual inspection,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",H34E,"Omicron BA.2 Variant, WHO",visual inspection,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",H34Q,"Omicron BA.2 Variant, WHO",visual inspection,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",K31R,"Omicron BA.2 Variant, WHO",visual inspection,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",K31W,"Omicron BA.2 Variant, WHO",visual inspection,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",K353R,"Omicron BA.2 Variant, WHO",visual inspection,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",T27I,"Omicron BA.2 Variant, WHO",visual inspection,X,X,
"G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H",T92C,"Omicron BA.2 Variant, WHO",visual inspection,X,X,