"Supplementary Data 1: Summary clinical and genomic features of the 82 exome samples, related to Fig. 3A and 3B. COSMIC signatures shown as a fraction contribution.",,,,,,,,,,,
Sample,Sample Type,Initial Diagnosis,Gleason,Tumor Purity,Whole Genome Doubling,Mutation Burden (Muts/Mb),COSMIC 1 (Aging),COSMIC 3 (HRD),COSMIC 6 (MMR),COSMIC 2/13 (APOBEC),Other COSMIC
RP-1532_PCProject_0013_T1_v2_Exome_OnPrem,FFPE,Localized,9,0.37,No,2.372,0.245265489,0.10567789,0,0,0.649056622
RP-1532_PCProject_0022_T1_v3_Exome_OnPrem,FFPE,Localized,9,0.54,No,1.125,0.62503147,0.164691148,0,0,0.210277382
RP-1532_PCProject_0028_T2_v3_Exome_OnPrem,FFPE,Localized,7,0.35,No,2.461,0.792552895,0,0,0,0.207447105
RP-1532_PCProject_0031_T1_v2_Exome_OnPrem,FFPE,Localized,9,0.24,No,4.215,0.128134668,0,0,0,0.871865332
RP-1532_PCProject_0035_T1_v3_Exome_OnPrem,FFPE,Localized,9,0.63,No,1.34,0.325187044,0.090973438,0,0.063976653,0.519862864
RP-1532_PCProject_0036_T1_v3_Exome_OnPrem,FFPE,Metastatic,9,0.57,Yes,1.467,0.269873951,0,0,0.067508291,0.662617758
RP-1532_PCProject_0041_T1_v3_Exome_OnPrem,FFPE,Metastatic,9,0.53,No,1.957,0.556696023,0.109159068,0,0,0.334144909
RP-1532_PCProject_0048_T1_v3_Exome_OnPrem,FFPE,Localized,8,0.2,No,1.303,1,0,0,0,0
RP-1532_PCProject_0054_T2_v2_Exome_OnPrem,FFPE,Metastatic,7,0.4,No,5.657,0.235107007,0.147875991,0,0,0.617017002
RP-1532_PCProject_0056_T1_v4_Exome_OnPrem,FFPE,Metastatic,8,0.4,No,5.223,0.451824532,0.463920033,0,0,0.084255435
RP-1532_PCProject_0057_T1_v3_Exome_OnPrem,FFPE,Localized,8,0.24,No,1.024,0.421455146,0,0,0,0.578544854
RP-1532_PCProject_0062_T1_v2_Exome_OnPrem,FFPE,Localized,7,0.42,No,0.756,1,0,0,0,0
RP-1532_PCProject_0085_T1_v3_Exome_OnPrem,FFPE,Localized,7,0.17,No,0.622,0.454633467,0,0,0,0.545366533
RP-1532_PCProject_0087_T1_v2_Exome_OnPrem,FFPE,Localized,9,0.28,No,0.709,,,,,
RP-1532_PCProject_0093_T2_v2_Exome_OnPrem,FFPE,Metastatic,9,0.62,No,8.105,1,0,0,0,0
RP-1532_PCProject_0100_T1_v4_Exome_OnPrem,FFPE,Localized,9,0.37,No,1.554,1,0,0,0,0
RP-1532_PCProject_0120_T2_v4_Exome_OnPrem,FFPE,Metastatic,7,0.71,No,3.686,0.91586369,0,0,0,0.08413631
RP-1532_PCProject_0123_T2_v4_Exome_OnPrem,FFPE,Localized,7,0.36,No,3.403,1,0,0,0,0
RP-1532_PCProject_0125_T1_v3_Exome_OnPrem,FFPE,Localized,7,0.2,No,0.398,,,,,
RP-1532_PCProject_0130_T1_v3_Exome_OnPrem,FFPE,Localized,9,0.2,No,0.717,,,,,
RP-1532_PCProject_0136_T2_v4_Exome_OnPrem,FFPE,Localized,7,0.3,No,4.532,1,0,0,0,0
RP-1532_PCProject_0142_T2_v4_Exome_OnPrem,FFPE,Localized,8,0.51,No,1.322,0.666118556,0,0,0,0.333881444
RP-1532_PCProject_0149_T1_v2_Exome_OnPrem,FFPE,Localized,7,0.34,No,4.049,0.260388235,0,0,0,0.739611765
RP-1532_PCProject_0161_T1_v2_Exome_OnPrem,FFPE,Localized,9,0.56,No,1.348,0.746088165,0.120100253,0,0,0.133811581
RP-1532_PCProject_0177_T1_v2_Exome_OnPrem,FFPE,Localized,10,0.29,No,1.06,0.583219721,0,0,0,0.416780279
RP-1532_PCProject_0181_T2_v3_Exome_OnPrem,FFPE,,7,0.55,Yes,2.583,0.448506427,0,0,0,0.551493573
RP-1532_PCProject_0182_T1_v2_Exome_OnPrem,FFPE,Metastatic,8,0.75,No,2.694,0.263017114,0,0,0,0.736982886
RP-1532_PCProject_0186_T1_v2_Exome_OnPrem,FFPE,Localized,7,0.31,No,3.811,0.249349276,0,0,0.084710639,0.665940085
RP-1532_PCProject_0187_T1_v3_Exome_OnPrem,FFPE,Metastatic,10,0.34,No,1.687,1,0,0,0,0
RP-1532_PCProject_0190_T1_v1_Exome_OnPrem,FFPE,Metastatic,9,0.6,Yes,1.449,1,0,0,0,0
RP-1532_PCProject_0193_T1A_v2_Exome_OnPrem,FFPE,Metastatic,10,0.56,No,2.66,0.269825248,0,0,0.099439142,0.63073561
RP-1532_PCProject_0212_T1_v4_Exome_OnPrem,FFPE,Localized,6,0.32,No,0.9,,,,,
RP-1532_PCProject_0213_T1_v2_Exome_OnPrem,FFPE,Metastatic,9,0.56,No,1.014,0.466461646,0,0,0,0.533538354
RP-1532_PCProject_0215_T1_v4_Exome_OnPrem,FFPE,Metastatic,8,0.75,No,1.891,0.851209338,0,0,0,0.148790662
RP-1532_PCProject_0225_T2_v4_Exome_OnPrem,FFPE,Metastatic,9,0.34,No,3.866,1,0,0,0,0
RP-1532_PCProject_0234_T1_v3_Exome_OnPrem,FFPE,Localized,8,0.42,No,16.285,0.786194321,0,0,0,0.213805679
RP-1532_PCProject_0254_T1_v2_Exome_OnPrem,FFPE,Localized,9,0.37,No,1.658,0.331739978,0.371831357,0.080071352,0,0.216357312
RP-1532_PCProject_0256_T1B_v1_Exome_OnPrem,FFPE,Metastatic,10,0.78,No,1.885,0.689606972,0.175793131,0,0,0.134599896
RP-1532_PCProject_0319_T1_v2_Exome_OnPrem,FFPE,Metastatic,7,0.26,No,1.348,0.410130031,0.11303911,0,0,0.476830859
RP-1532_PCProject_0336_T1_v4_Exome_OnPrem,FFPE,Localized,7,0.57,Yes,2.275,0.239142518,0,0,0,0.760857482
RP-1532_PCProject_0357_T2_v3_Exome_OnPrem,FFPE,Localized,9,0.29,Yes,3.268,0.286576066,0.110489414,0,0,0.60293452
RP-1532_PCProject_0364_T2_v4_Exome_OnPrem,FFPE,Localized,7,0.33,No,1.486,0.858736612,0.065868887,0.075394501,0,0
RP-1532_PCProject_0381_T2_v4_Exome_OnPrem,FFPE,Localized,7,0.25,No,1.743,1,0,0,0,0
RP-1532_PCProject_0392_T2_v4_Exome_OnPrem,FFPE,Localized,7,0.45,Yes,10.635,1,0,0,0,0
RP-1532_PCProject_0399_T2_v4_Exome_OnPrem,FFPE,Localized,8,0.52,No,2.586,0.277764541,0.093856536,0,0,0.628378923
RP-1532_PCProject_0410_T1_v4_Exome_OnPrem,FFPE,Metastatic,9,0.66,No,6.133,0.686937174,0.108565434,0,0,0.204497392
RP-1532_PCProject_0439_T2_v4_Exome_OnPrem,FFPE,Localized,8,0.58,No,2.809,0.280888423,0.379400808,0,0,0.339710769
RP-1532_PCProject_0443_T2_v4_Exome_OnPrem,FFPE,Localized,8,0.3,No,1.923,0.844041326,0,0,0,0.155958674
RP-1532_PCProject_0445_T2_v4_Exome_OnPrem,FFPE,Localized,9,0.3,No,2.73,0.705460078,0.294539922,0,0,0
RP-1532_PCProject_0488_T1_v4_Exome_OnPrem,FFPE,Metastatic,9,0.2,No,2.356,0.151504283,0.364900651,0.404718332,0,0.078876734
RP-1532_PCProject_0495_T1_v2_Exome_OnPrem,FFPE,Metastatic,7,0.5,No,0.819,,,,,
RP-1532_PCProject_0501_T1_v4_Exome_OnPrem,FFPE,Metastatic,8,0.34,No,5.038,0.809005896,0.190994104,0,0,0
RP-1532_PCProject_0524_T1_v4_Exome_OnPrem,FFPE,Metastatic,8,0.5,No,9.032,1,0,0,0,0
RP-1532_PCProject_0525_T2_v3_Exome_OnPrem,FFPE,Localized,9,0.2,No,1.655,0.661444517,0,0,0,0.338555483
RP-1532_PCProject_0557_T2_v3_Exome_OnPrem,FFPE,Metastatic,9,0.51,No,1.81,0.331281935,0,0.12316381,0,0.545554255
RP-1532_PCProject_0575_T1_v4_Exome_OnPrem,FFPE,Localized,8,0.48,No,3.665,0.503882455,0.327333324,0,0,0.168784221
RP-1532_PCProject_0588_T2_v2_Exome_OnPrem,FFPE,Localized,9,0.73,No,3.915,0.219362927,0,0,0,0.780637073
RP-1532_PCProject_0608_T2_v4_Exome_OnPrem,FFPE,Metastatic,7,0.43,No,8.675,1,0,0,0,0
RP-1532_PCProject_0639_T1_v3_Exome_OnPrem,FFPE,Metastatic,9,0.24,No,3.171,0.133443221,0.143932547,0,0,0.722624232
RP-1532_PCProject_0643_T2_v4_Exome_OnPrem,FFPE,Localized,9,0.2,No,0.881,0.880639022,0.119360978,0,0,0
RP-1532_PCProject_0653_T2_v4_Exome_OnPrem,FFPE,Localized,7,0.33,No,1.946,0.633596607,0.19810524,0,0,0.168298153
RP-1532_PCProject_0672_T1_v6_Exome_OnPrem,FFPE,Metastatic,9,0.5,No,0.559,,,,,
RP-1532_PCProject_0683_T2_v3_Exome_OnPrem,FFPE,Localized,9,0.25,No,3.245,0.371394751,0.175846412,0.452758837,0,0
RP-1532_PCProject_0002_BLOOD_v1_Exome_OnPrem,cfDNA,Metastatic,10,0.36,Yes,1.441,0.629995445,0.15060993,0.219394625,0,0
RP-1532_PCProject_0009_BLOOD_P_v1_Exome_OnPrem,cfDNA,Localized,NR,0.62,No,1.496,0.619910945,0,0.200911048,0,0.179178008
RP-1532_PCProject_0029_BLOOD_P_v1_Exome_OnPrem,cfDNA,Localized,8,0.25,No,1.896,0.302939559,0,0.349518655,0.070730538,0.276811248
RP-1532_PCProject_0030_BLOOD_P_v1_Exome_OnPrem,cfDNA,Metastatic,8,0.28,No,1.058,0.371961118,0,0,0,0.628038882
RP-1532_PCProject_0083_BLOOD_P_v1_Exome_OnPrem,cfDNA,Localized,6,0.28,No,0.074,,,,,
RP-1532_PCProject_0093_BLOOD_P_v1_Exome_OnPrem,cfDNA,Metastatic,9,0.2,No,1.874,0.56418987,0,0,0,0.43581013
RP-1532_PCProject_0172_BLOOD_P_v1_Exome_OnPrem,cfDNA,Metastatic,NR,0.29,No,2.22,0.26541209,0,0,0.216508678,0.518079232
RP-1532_PCProject_0203_BLOOD_P_v1_Exome_OnPrem,cfDNA,Localized,9,0.19,No,1.702,0.441611589,0,0.10888553,0.066512386,0.382990495
RP-1532_PCProject_0207_BLOOD_2_P_v3_Exome_OnPrem,cfDNA,Metastatic,9,0.24,No,1.698,0.287144611,0.178618314,0.349516094,0,0.184720981
RP-1532_PCProject_0213_BLOOD_P_v1_Exome_OnPrem,cfDNA,Metastatic,9,0.24,No,1.261,0.274787317,0,0,0.074940111,0.650272572
RP-1532_PCProject_0294_BLOOD_P_v1_Exome_OnPrem,cfDNA,Localized,9,0.28,No,1.455,0.555497175,0,0,0,0.444502825
RP-1532_PCProject_0296_BLOOD_P_v1_Exome_OnPrem,cfDNA,Metastatic,8,0.31,Yes,1.077,0.34802803,0.152424996,0,0,0.499546973
RP-1532_PCProject_0328_BLOOD_P_v1_Exome_OnPrem,cfDNA,Metastatic,NR,0.12,No,1.238,0.650060937,0,0.141695115,0,0.208243948
RP-1532_PCProject_0411_BLOOD_P_v3_Exome_OnPrem,cfDNA,Localized,7,0.47,No,5.055,0.300287831,0,0,0,0.699712169
RP-1532_PCProject_0413_BLOOD_P_v1_Exome_OnPrem,cfDNA,Localized,NR,0.18,No,0.519,,,,,
RP-1532_PCProject_0420_BLOOD_P_v1_Exome_OnPrem,cfDNA,Localized,7,0.4,No,2.112,0.340897197,0.340740556,0.231196309,0,0.087165938
RP-1532_PCProject_0495_BLOOD_P_v3_Exome_OnPrem,cfDNA,Metastatic,7,0.45,No,1.703,0.698481519,0,0,0,0.301518481
RP-1532_PCProject_0503_BLOOD_P_v3_Exome_OnPrem,cfDNA,Metastatic,8,0.2,No,1.799,0.231511908,0,0.2392979,0,0.529190192
RP-1532_PCProject_0521_BLOOD_P_v3_Exome_OnPrem,cfDNA,Localized,9,0.24,No,0.939,0.720565264,0,0.279434736,0,0