Patient 4: A: Electrical seizure lasting 13.1 s recorded during EEG-fMRI test. Right temporoparietal and occipital discharges propagating to the left homologous regions observed in a referencial montage (reference FCz). B: F-maps obtained on 6-s windows data every 2 s. No response between −7 and 3 s; this line is used to show the anatomical MRI and bilateral band heterotopia predominating over parietal, occipital and temporal areas, maximum on the right side (white arrow heads). First significant activation (yellow–red scale) starts at peak 5 with a bilateral involvement of the cortex surrounding the heterotopic band. There is a late involvement of the lesion (starting at peaks 11–13 only). Deactivation (white–blue scale) appears mostly in the second part of the seizure, at first around the first activation area and later around the propagated activation areas (maximum on the right side, as the activation). C: After lowering the statistical threshold to 3.5, successive F-maps preceding the first significant activation map (peak 5) showed new activation located in a similar area as the first significant activation. From peak −3 to peak 1, the activation was unilateral and more focal over the right temporal region.