. Author manuscript; available in PMC: 2021 Sep 16.

Published in final edited form as: Mol Psychiatry. 2021 Jan 4;26(6):2651–2662. doi: 10.1038/s41380-020-00975-1

Table 2.

Associations between factors of cortical change and APOE status, and changes in cognitive domains.

	Global	Fronto-temporal Factor	Occipito-parietal Factor
APOE e4 carrier	-0.100 (0.038)	-0.044 (0.414)	0.012 (0.774)
g	0.431 (<0.001)	-0.024 (0.738)	-0.072 (0.212)
Visuospatial	0.415 (0.002)	-0.139 (0.286)	-0.143 (0.229)
Processing Speed	0.369 (<0.001)	-0.010 (0.893)	-0.066 (0.256)
Memory	0.363 (<0.001)	0.066 (0.352)	-0.026 (0.644)

Note. Standardised estimates (p-values) are reported for associations between the three factors of cortical volumetric change (global, fronto-temporal and posterior-parietal), APOE status (where 1 = at least 1 × e4 allele), and the three cognitive domains (visuospatial, processing speed and memory). Bold typeface denotes FDR-q < 0.05.