Table 1.
Patients clinical and recording details. Pre-OP: pre-operative; Post-OP: post-operative; UPDRS-III: Unified Parkinson’s disease Rating Scale (subunit III); FTG: finely-tuned gamma; Boston: Boston Scientific; Medt: Medtronic; STN (SP): superior-posterior part of the subthalamic nucleus; FOG: freezing of gait; STN/cZI: subthalamic nucleus/caudal Zona incerta; LID: levodopa-induced dyskinesia; RDRS: Rush Dyskinesia Rating Scale; DID: DBS-induced dyskinesia; n.a.: not applicable.
| Patient | Gender (m/f) | Age (yr) | Disease Duration (yr) | Pre-OP UPDRS-III OFF | Pre-OP UPDRS-III ON | Pre-dominant symptoms | DBS lead | Time Recording (d) | STN tested (L/R) | Location Stim.Contact | Stim. Amp. (mA) | FTG present OFF meds ON DBS | LID contralat.to tested STN pre-OP (RDRS) | DID contralat. to tested STN post-OP |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | m | 48 | 17 | 71 | 37 | tigidity, gait freezing (FOG), tremor | Boston | 4 | R | STN (SP) | 2 | yes | yes (6) | no |
| 2 | m | 54 | 7 | 38 | 24 | tremor | Boston | 5 | R | STN (SP) | 3.5 | yes | no (0) | yes |
| 3 | m | 51 | 5 | 27 | 13 | bradykinesia, rigidity, motor fluctuations | Boston | 4 | R | STN/cZI | 4 | yes | no (0) | yes |
| 4 | m | 64 | 13 | 52 | 21 | FOG, motor fluctuations | Boston | 4 | R | STN (SP) | 2 | yes | no (0) | no |
| 5 | m | 53 | 7 | 23 | 12 | Tremor | Boston | 4 | R | STN (SP) | 2 | no | no (0) | no |
| 5 | L | STN (SP) | 3 | yes | no (0) | no | ||||||||
| 6 | m | 61 | 16 | 50 | 30 | FOG, motor fluctuations | Boston | 3 | L | STN (SP) | 2 | no | no (0) | no |
| 7 | m | 56 | 16 | 51 | 19 | Rigidity, bradykinesia | Medt | 4 | L | STN (SP) | 4 | no | no (0) | no |
| 8 | m | 65 | 5 | 34 | 16 | FOG, motor fluctuations | Boston | 4 + 5 | L | STN/cZI | 3 | no | yes (2) | no |
| 4 | R | STN/cZI | 2.5 | no | yes (3) | yes | ||||||||
| 9 | f | 63 | 11 | 40 | 17 | FOG, motor fluctuations | Boston | 4 | L | STN (SP) | 2 | no | yes (2) | no |
| 10 | m | 65 | 15 | 77 | 27 | Akinetic-rigid, tremor | Boston | 5 | L | STN (SP) | 1.8 | no | yes (1) | no |
| 11 | m | 61 | 9 | 33 | 12 | Rigth arm tremor,bradykinesia | Boston | 4 | L | STN/cZI | 4 | no | no (0) | no |
| 12 | m | 48 | 8 | 45 | 34 | Tremor, bradykinesia | Boston | 5 | L | STN/cZI | 3 | no | no (0) | no |
| 13 | m | 59 | 6 | 48 | 14 | Akinetic-rigid | Medt | 5 | R | STN (SP) | n.a. | no | yes (1) | no |
| 14 | m | 53 | 7 | 18 | 1 | Motor fluctuations, dyskinesia | Boston | 4 | L | STN/cZI | 4 | no | no (0) | no |
| 4 | R | STN/cZI | 2.5 | no | yes (1) | no |