Manhattan plot for genome-wide association analysis of 100,285 Chinese subjects in CKB cohort for three lung function traits, FEV1 (panel A), FVC (panel B), and FEV1/FVC (panel C). X-axis denotes the genomic position (chromosomes 1-22), Y-axis denotes the –log10(P-value) of association test and starts at –log10(P-value)=3. The most significant novel variant in each independent clump is highlighted in yellow orange diamond shape. Genes that are labeled in black font are previously reported, and genes that are labeled in red font are novel. Asterisk on some genes means novel variant. Genome-wide significance level (P=5×10-8) is denoted by red line.