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. Author manuscript; available in PMC: 2021 Jul 23.
Published in final edited form as: Mol Aspects Med. 2021 Jul 23;81:101004. doi: 10.1016/j.mam.2021.101004

Fig. 6. Golgi Ca2+ signaling and viral exit.

Fig. 6

Viruses frequently target Golgi Ca2+ signaling for facilitating their maturation and exit from the host cells. For example, DENV, ZIKV, CHIKV, RSV and Measles virus act on Golgi localized SPCA for enabling maturation of their glycoproteins and for their exit from the host cells. Further, SPCA regulated Golgi and cytosolic Ca2+ homeostasis plays a critical role in AAV transduction.