Table 1. Age of LmnaHGPSrev-Ubc-CreERT2 mice at the time of initiation of oil or tamoxifen administration.
Disease stage (age initiation oil/tamoxifen administration) | Age at initiation of oil/tamoxifen administration (mean ± SD) | Experiments |
---|---|---|
Early disease (≈6-month-old; symptoms emerging) | 24.3 ± 2.15 weeks | Body-weight evolution and survival |
Intermediate disease (≈9-month-old; mild symptoms) | 35.9 ± 3.2 weeks | Electrocardiography and histopathology |
Late disease (≈13-month-old; severe symptoms) | 54.4 ± 1.97 weeks | Body-weight evolution and survival |
SD, standard deviation