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. Author manuscript; available in PMC: 2022 Jul 4.
Published in final edited form as: Clin Cancer Res. 2022 Jul 1;28(13):2911–2922. doi: 10.1158/1078-0432.CCR-21-1643

Figure 6. Cluster ploidy and whole genome duplication.

Figure 6

(A) Ploidy distribution of late-stage samples in three clusters. Kruskal Wallis test.

(B) Correlation between CN signature 4 exposure and ploidy across both cohorts. Spearman rank correlation.

(C) Fraction of CN segments with absolute copy number ≥3 in three clusters. Kruskal Wallis test.

(D) Copy number changepoint. Graphical depiction of CN changepoint (left); distribution of copy number changepoint ≥+2 in the three clusters. Kruskal Wallis test (centre); density distribution (right).

(E) Overall survival of combined early and late-stage cohorts by ploidy. Log-rank for trend analysis.