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. Author manuscript; available in PMC: 2022 Apr 28.
Published in final edited form as: Circulation. 2022 Mar 7;145(17):1312–1323. doi: 10.1161/CIRCULATIONAHA.121.057631

Table 1. Statin eligibility criteria and percentage eligible for treatment under different treatment strategies.

10-Year CVD Risk
Threshold (% Eligible)
10-Year ARR
Threshold (% Eligible)
ASSIGN
20
ASSIGN
10
Age-Strat
20
Age-Strat
10
ARR
20
ARR
10
Age-Group (Years) 40-44 20.0 (0.2) 10.0 (4.7) 4.8 (32.1) 3.3 (57.7) 3.97 (0.8) 2.00 (8.0)
45-49 20.0 (1.2) 10.0 (14.0) 7.2 (32.1) 4.9 (57.7) 3.97 (2.6) 2.00 (20.0)
50-54 20.0 (3.6) 10.0 (33.9) 10.3 (32.1) 7.2 (57.7) 3.97 (7.8) 2.00 (39.2)
55-59 20.0 (13.4) 10.0 (60.5) 14.4 (32.1) 10.4 (57.7) 3.97 (20.5) 2.00 (59.8)
60-64 20.0 (32.9) 10.0 (81.6) 20.4 (32.1) 14.9 (57.7) 3.97 (36.8) 2.00 (76.0)
65-69 20.0 (57.6) 10.0 (95.2) 26.6 (32.1) 20.0 (57.7) 3.97 (54.1) 2.00 (87.9)
70-74 20.0 (79.6) 10.0 (100.0) 36.4 (32.1) 26.9 (57.7) 3.97 (69.3) 2.00 (95.5)
75-79 20.0 (96.0) 10.0 (99.6) 43.8 (32.1) 34.8 (57.7) 3.97 (86.9) 2.00 (98.2)
80+ 20.0 (100.0) 10.0 (100.0) 62.9 (32.1) 48.8 (57.7) 3.97 (91.2) 2.00 (99.3)
Overall 20.0 (32.1) 10.0 (57.7) n/a (32.1) n/a (57.7) 3.97 (32.1) 2.00 (57.7)

ARR – absolute risk reduction; Age-Strat – age-stratified risk thresholds; CVD – cardiovascular disease