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. Author manuscript; available in PMC: 2022 Apr 26.
Published in final edited form as: Nat Med. 2022 Mar 14;28(4):743–751. doi: 10.1038/s41591-022-01720-7

Extended Data Fig. 2. Identification of cancer cells in leukemia scRNA-seq data using immunophenotype gene expression.

Extended Data Fig. 2

UMAP projections of leukaemia scRNA-seq data sets, coloured by Louvain cluster. Accompanying dotplots show per-cluster expression of B-ALL immunophenotype genes or AML immunophenotype genes and lineage-defining genes of monocytes (Mo.), T cells (T), NK cells (NK), B cells (B) and progenitors (Pro.). Dot colour denotes log-transformed, normalised and scaled gene expression value, while dot size indicates percentage of cells in each cluster expressing the stated gene. Immunophenotypes are provided in Supplementary Table 4.