Skip to main content
. Author manuscript; available in PMC: 2022 Jun 8.
Published in final edited form as: Hypertension. 2022 May 9;79(7):1525–1535. doi: 10.1161/HYPERTENSIONAHA.122.19175

Figure 5. Hypoxic pregnancy changes placental expression of anti-angiogenic factors, increasing the anti- to pro-angiogenic balance in maternal plasma.

Figure 5

Upper panel: Values are mean ± SEM for the relative placental fold change for sFlt-1 (A), sEng (B) and the ratio of sFlt-1 to VEGF (C). Lower panel: Values are mean ± SEM for plasma concentration of sFlt-1 (D) and plasma ratios of sFlt-1 to PlGF (E) and to VEGF (F). Groups are N (○,n=7-9) and H (●,n=7). Significant differences (P<0.05) are *N vs. H or † vs baseline; Student’s t-test for unpaired data or two-way RM-ANOVA where appropriate.