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. Author manuscript; available in PMC: 2023 Jan 5.
Published in final edited form as: Clin Cancer Res. 2022 Jun 2;28(16):3618–3629. doi: 10.1158/1078-0432.CCR-21-3189

Figure 3. Differential gene expression in resistant tumors.

Figure 3

A, Hierarchical clustering of batch corrected RNA gene expression of significantly differentially expressed genes in resistant tumors (N=24 from 17 patients) compared to matched sensitive tumors (N=29 from 17 patients) using linear mixed models. B, Gene ontology terms associated with up-regulated genes in resistant tumors. C, Boxplot indicating median score and inter-quartile range of proliferation scores in resistant and sensitive tumors.