Selected summary forest plots showing sensitivity and specificity estimates (with 95% CI) for MTBDRplus and MTBDRsl. Importantly, only patients first detected as TB positive (top two rows) can generate an actionable LPA DST result. Estimates for smear-negatives were lower than smear-positives and, overall, estimates for SLIDs were lower than for FQs. All estimates improved in favour of LPAs after discrepant resolution.
Abbreviations: TB-tuberculosis, FQ-fluoroquinolones, SLID-second line injectable drugs