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. Author manuscript; available in PMC: 2023 Mar 16.
Published in final edited form as: Nat Cell Biol. 2023 Jan 23;25(3):481–492. doi: 10.1038/s41556-022-01075-8

Extended Data Fig. 7. VFG expansion insures higher fidelity regulation of enhancers normally exploited in fetal organogenesis.

Extended Data Fig. 7

a-b, Enrichment of tissue-specific (a) and lineage-specific (b) H3K27ac enhancers from human embryos (from two independent experiments for most tissue types, except for stomach where only one sample was available) in different ATAC clusters defined in Fig. 3c were displayed by enrichment score (observed/expected) in radar charts. c-d, Enrichment of tissue-specific (c) and lineage-specific (d) H3K27ac enhancers from human embryos (from two independent experiments for most tissue types, except for stomach where only one sample was available) across different VFG-specific ATAC clusters defined in Extended Data Fig. 4a by enrichment score (observed/expected) in a radar chart. P: pancreas, Lv: liver, H: heart, A: adrenal, B: brain, R: RPE, Ln: lung, S: stomach.