Figure 2.
Cytokine responses in Alternaria-challenged airways. Mice were treated with Alternaria allergen with or without Hp-TGM as described for Figure 1 and samples recovered at 24 h. (a) IL-5 cytokine measured in cell-free BALF supernatants. (b–e) IL-33 (b), IL-5 (c), IL-13 (d), eotaxin-1 (e) cytokines measured in lung homogenates. Results are pooled from two independent experiments each with 3–4 mice per group. All data were analysed using Prism (Graphpad Software Inc.), one-way ANOVA with Tukey’s multiple comparisons post-test was used to compare multiple independent groups. Mean values and SEM are indicated. **p < 0.01; *p < 0.05; non-significant differences not shown.