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. Author manuscript; available in PMC: 2023 Dec 2.
Published in final edited form as: Brain. 2023 Jul 11;146(12):5015–5030. doi: 10.1093/brain/awad233

Figure 6. Beta and gamma power were both suppressed during DBS compared with no DBS, and the suppression was stronger during CDBS compared with ADBS.

Figure 6

(A) Group averaged beta power aligned to movement onset during reaching movement under different conditions. The power was normalized against the average beta power during the 1-s pre-Go cue resting period under the no DBS condition. Solid line and shade indicate the mean and SEM of the beta power, respectively. Grey and pink bars on the bottom indicate the significant difference between no DBS and CDBS, and between no DBS and ADBS based on a cluster-based permutation procedure, respectively. (B and C) Averaged beta power without baseline normalization in (B) a baseline time window (W1, 1-0.5 s pre-Onset) and (C) a 0.2-s time window around movement initiation (W2) under different conditions. (D) The same as A but for gamma power. (E and F) Averaged (E) beta and (F) gamma power without baseline normalization during movement under different conditions. The error bar plots show the mean and SEM across all tested hemispheres under different conditions. *P < 0.05, **P < 0.01, ***P < 0.001. P-values were quantified using generalized linear mixed effect modelling on an individual trial basis and corrected for multiple comparisons using Bonferroni correction. ADBS = adaptive deep brain stimulation; CDBS = continuous deep brain stimulation; DBS = deep brain stimulation; n.s. = not significant; SEM = standard error of the mean.