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. Author manuscript; available in PMC: 2024 Jun 3.
Published in final edited form as: Eur J Prev Cardiol. 2024 Jan 10;31(8):1015–1025. doi: 10.1093/eurjpc/zwae009

Figure 2. Associations of genetic scores for (A) PCSK9 and (B) LDL cholesterol with risk of vascular and non-vascular disease endpoints.

Figure 2

Odds ratios are estimated using logistic regression of the weighted PCSK9 genetic score, scaled to a 1-SD lowering of LDL cholesterol, calculated as an inverse-variance weighted average of region-specific estimates with adjustment for age, age2, sex, ascertainment, and region-specific principal components.