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. Author manuscript; available in PMC: 2013 Nov 21.
Published in final edited form as: J Neurosci. 2011 Feb 2;31(5):10.1523/JNEUROSCI.2610-10.2011. doi: 10.1523/JNEUROSCI.2610-10.2011

Figure 2. Human Aβ1-42 does not reduce LTP in slices of Tau−/− mice.

Figure 2

(a, b) Hippocampal Schaffer collateral-CA1 LTP in wild-type (a) and Tau−/− mice (b) in control ACSF (black), or after incubation with hAβ1-42 (red) or the control peptide hAβ42-1 (gray). The insets show superimposed example traces before and 40 min after high-frequency stimulation for each condition. Scale bars: 5 ms, 200 μV. (c) Summary of results 40-45 min after high-frequency stimulation. Error bars are s.e.m. ** P < 0.01. The numbers of slices are shown in parentheses.