Figure 1. Synaptic vesicle density is reduced in presynaptic terminals of synapsin TKO neurons.
(A) Synaptobrevin 2 immunofluorescence image of cultured WT (left) and synapsin TKO (right) neurons. TKO synapses are dimmer than WT synapses. (B) Cumulative probability plots of the normalized intensity of synaptobrevin synaptic puncta of WT and synapsin TKO neurons. The intensity was determined at the center of mass of each synapse and was normalized by the average per image value of WT synapses in each experimental session.