Table 3.
Representation of coagulation factor genes on the HumanCVD array.
| Coagulation Factor | Gene symbol | Number of SNPs |
|---|---|---|
| Fibrinogen | FGA | 23 |
| Fibrinogen | FGB | 28 |
| Fibrinogen | FGG | 20 |
| Prothrombin | F2 | 36 |
| Tissue Factor | F3 | 38 |
| Factor V | F5 | 126 |
| Factor VII | F7 | 34 |
| Factor VIII | F8 | 19 |
| Factor IX | F9 | 18 |
| Factor X | F10 | 20 |
| Factor XI | F11 | 20 |
| Factor XII | F12 | 19 |
| Factor XIII | F13A1 | 133 |
| Factor XIII | F13B | 9 |
| Von Willebrand Factor | VWF | 128 |
| Prekallikrein | KLKB1 | 21 |
| Fibronectin | FN | 0 |
| Antithrombin III | SERPINC1 | 9 |
| Heparin cofactor II | SERPIND1 | 5 |
| Protein C | PROC | 8 |
| Protein S | PROS1 | 8 |
| Protein Z | PROZ | 6 |
| Protein Z-related protease inhibitor (ZPI) | SERPINA10 | 11 |
| Plasminogen | PLG | 35 |
| Alpha 2-antiplasmin | SERPINF2 | 7 |
| Tissue Plasminogen Activator | PLAT | 19 |
| Plasminogen Activator | PLAU | 6 |
| Plasminogen Activator Inhibitor-1 | SERPINE1 | 33 |
| Plasminogen Activator Inhibitor-2 | SERPINB2 | 16 |
For each of the main proteins in the coagulation cascade the corresponding gene(s) is/are shown, along with the number of SNPs included in the HumanCVD array for that gene.