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. Author manuscript; available in PMC: 2013 Jun 26.
Published in final edited form as: J Neurosci. 2011 Jun 15;31(24):8803–8811. doi: 10.1523/JNEUROSCI.6616-10.2011

Figure 2.

Figure 2

Diagram of the 2-tissue 4 rate-constant (2T4K) compartmental model used for the kinetic modeling of (R)-[11C]verapamil PET data. Cp(t) is the arterial input function; C1(t) and C2(t) describe the radioactivity concentrations in the first and second tissue compartment. The rate constants K1, k2, k3 and k4 describe the exchange of radioactivity between the plasma, the first and the second tissue compartment.