Methods | Method of randomisation was not reported and allocation concealment was unclear. Baseline comparability was unclear. However the study reported that, “no significant difference between groups were detected at any stage of the study.” Participants were not blind to treatment allocation and blinding of the outcome assessor was unclear [Russian article] | |
Participants | 66 patients undergoing elective coronary artery bypass surgery (CABG) were randomly allocated to one of two groups:
Inclusion criteria: patients with an uneventful postoperative period (discharge of less than 800mls through draining tubes during first 8 hours post operation) |
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Interventions |
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Outcomes | Outcomes reported: number of patients transfused allogeneic blood. | |
Notes | Transfusion threshold: transfusion protocol not reported. Russian study. English abstract only | |
Risk of bias | ||
Bias | Authors’ judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Method used to generate allocation sequences was not described |
Allocation concealment (selection bias) | High risk | Allocation concealment was not used. |
Blinding (performance bias and detection bias) All outcomes |
High risk |