Methods | A randomised, prospective study of patients undergoing primary total hip or total knee replacement over a six-month period. Method of randomisation and allocation concealment were not described | |
Participants | 415 patients undergoing primary total hip or total knee replacement were randomly allocated to one of two groups:
|
|
Interventions |
|
|
Outcomes | Outcomes reported: number of patients transfused allogeneic blood, amount of transfused blood, adverse events, knee flexion | |
Notes | Transfusion threshold: allogeneic blood was transfused if the haemoglobin level fell below 9.0g/dL | |
Risk of bias | ||
Bias | Authors’ judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Method used to generate allocation sequences was not described |
Allocation concealment (selection bias) | Unclear risk | Method used to conceal treatment allocation was not described |
Blinding (performance bias and detection bias) All outcomes |
High risk |