Methods	Randomised controlled trial was conducted to investigate the effectiveness of pre-operative plateletpheresis combined with intra-operative autotransfusion on the blood coagulation of orthopaedic patients.[Chinese]
Participants	60 patients undergoing orthopaedic procedures were randomly allocated to one of three groups: Group 1 (Autotransfusion group): n=20 Group 2 (Platelet-rich plasmapheresis + autotransfusion group): n=20 Group 3 (Control group): n=20 NB: Demographic data not reported for each trial arm.
Interventions	Group 1: Autotransfusion group received intra-operative autotransfusion of shed blood using the Haemonetics Cell Saver 5 system. Group 2: Platelet-rich plasmapheresis group received platelet-rich plasma (PRP) and autotransfusion with the use of the Haemonetics Cell Saver 5 system. Group 3: Control group received standard care without PRP and autotransfusion.
Outcomes	Outcomes reported: number of patients transfused allogeneic blood, blood loss.
Notes	Transfusion threshold: uncertain.
Risk of bias
Bias	Authors’ judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Method used to generate allocation sequences was unclear.
Allocation concealment (selection bias)	Unclear risk	Method used to conceal treatment allocation was unclear.
Blinding (performance bias and detection bias) All outcomes	High risk