Comparison 1.
Cell salvage - blood transfused (all studies)
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
|---|---|---|---|---|
| 1 No. exposed to allogeneic blood (All Studies) | 67 | 6025 | Risk Ratio (M-H, Random, 95% CI) | 0.62 [0.55, 0.70] |
| 2 No. exposed to allogeneic blood (Transfusion Protocol) | 67 | Risk Ratio (M-H, Random, 95% CI) | Subtotals only | |
| 2.1 Transfusion Protocol | 52 | 4755 | Risk Ratio (M-H, Random, 95% CI) | 0.62 [0.54, 0.71] |
| 2.2 No Transfusion Protocol | 15 | 1270 | Risk Ratio (M-H, Random, 95% CI) | 0.58 [0.41, 0.82] |
| 3 No. exposed to allogeneic blood (Type of Surgery) | 67 | Risk Ratio (M-H, Random, 95% CI) | Subtotals only | |
| 3.1 Cardiac | 31 | 2518 | Risk Ratio (M-H, Random, 95% CI) | 0.77 [0.69, 0.86] |
| 3.2 Orthopaedic | 32 | 3240 | Risk Ratio (M-H, Random, 95% CI) | 0.46 [0.37, 0.57] |
| 3.3 Vascular | 4 | 267 | Risk Ratio (M-H, Random, 95% CI) | 0.63 [0.34, 1.15] |
| 4 No. exposed to allogeneic blood - (Washed vs Unwashed) | 67 | Risk Ratio (M-H, Random, 95% CI) | Subtotals only | |
| 4.1 Washed | 27 | 2225 | Risk Ratio (M-H, Random, 95% CI) | 0.60 [0.51, 0.70] |
| 4.2 Unwashed | 40 | 3717 | Risk Ratio (M-H, Random, 95% CI) | 0.66 [0.57, 0.77] |
| 5 No. exposed to allogeneic blood (Timing) | 66 | Risk Ratio (M-H, Random, 95% CI) | Subtotals only | |
| 5.1 Intra-operative cell salvage | 11 | 805 | Risk Ratio (M-H, Random, 95% CI) | 0.59 [0.46, 0.76] |
| 5.2 Post-operative cell salvage | 46 | 4361 | Risk Ratio (M-H, Random, 95% CI) | 0.63 [0.54, 0.74] |
| 5.3 Intra & post-operative cell salvage | 9 | 737 | Risk Ratio (M-H, Random, 95% CI) | 0.70 [0.54, 0.92] |
| 6 Units of allogeneic blood transfused (All Studies) | 32 | 2321 | Mean Difference (IV, Random, 95% CI) | −0.68 [−0.88, −0.49] |
| 7 Units of allogeneic blood transfused (Transfusion Protocol) | 32 | Mean Difference (IV, Random, 95% CI) | Subtotals only | |
| 7.1 Transfusion Protocol | 27 | 1950 | Mean Difference (IV, Random, 95% CI) | −0.69 [−0.90, −0.49] |
| 7.2 No Transfusion Protocol | 5 | 371 | Mean Difference (IV, Random, 95% CI) | −0.64 [−1.30, 0.01] |
| 8 Units of allogeneic blood transfused (Type of Surgery) | 32 | Mean Difference (IV, Random, 95% CI) | Subtotals only | |
| 8.1 Cardiac | 19 | 1497 | Mean Difference (IV, Random, 95% CI) | −0.67 [−0.89, −0.44] |
| 8.2 Orthopaedic | 10 | 638 | Mean Difference (IV, Random, 95% CI) | −0.81 [−1.22, −0.39] |
| 8.3 Vascular | 3 | 186 | Mean Difference (IV, Random, 95% CI) | 0.02 [−0.34, 0.38] |