Comparison 3.
Cell salvage - blood transfused (active versus control)
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
|---|---|---|---|---|
| 1 No. exposed to allogeneic blood (Active vs Control) | 43 | Risk Ratio (M-H, Random, 95% CI) | Subtotals only | |
| 1.1 Cell Salvage vs Control | 43 | 3666 | Risk Ratio (M-H, Random, 95% CI) | 0.61 [0.52, 0.71] |
| 2 No. exposed to allogeneic blood (Transfusion Protocol) | 43 | Risk Ratio (M-H, Random, 95% CI) | Subtotals only | |
| 2.1 Transfusion Protocol | 34 | 3030 | Risk Ratio (M-H, Random, 95% CI) | 0.61 [0.51, 0.73] |
| 2.2 No Transfusion Protocol | 9 | 636 | Risk Ratio (M-H, Random, 95% CI) | 0.56 [0.35, 0.89] |
| 3 No. exposed to allogeneic blood (Type of Surgery) | 43 | Risk Ratio (M-H, Random, 95% CI) | Subtotals only | |
| 3.1 Cardiac | 18 | 1257 | Risk Ratio (M-H, Random, 95% CI) | 0.78 [0.68, 0.91] |
| 3.2 Orthopaedic | 21 | 2142 | Risk Ratio (M-H, Random, 95% CI) | 0.45 [0.34, 0.60] |
| 3.3 Vascular | 4 | 267 | Risk Ratio (M-H, Random, 95% CI) | 0.63 [0.34, 1.15] |
| 4 No. exposed to allogeneic blood (Washed vs Unwashed) | 42 | Risk Ratio (M-H, Random, 95% CI) | Subtotals only | |
| 4.1 Washed | 18 | 1322 | Risk Ratio (M-H, Random, 95% CI) | 0.57 [0.45, 0.72] |
| 4.2 Unwashed | 24 | 2224 | Risk Ratio (M-H, Random, 95% CI) | 0.67 [0.56, 0.81] |
| 5 No. exposed to allogeneic blood (Timing) | 43 | Risk Ratio (M-H, Random, 95% CI) | Subtotals only | |
| 5.1 Intra-operative cell salvage | 8 | 564 | Risk Ratio (M-H, Random, 95% CI) | 0.64 [0.50, 0.83] |
| 5.2 Post-operative cell salvage | 29 | 2852 | Risk Ratio (M-H, Random, 95% CI) | 0.59 [0.48, 0.73] |
| 5.3 Intra & post-operative cell salvage | 6 | 250 | Risk Ratio (M-H, Random, 95% CI) | 0.58 [0.35, 0.95] |
| 6 Units of allogeneic blood transfused (Active vs Control) | 23 | Mean Difference (IV, Random, 95% CI) | Subtotals only | |
| 6.1 Cell Salvage vs Control | 23 | 1608 | Mean Difference (IV, Random, 95% CI) | −0.81 [−1.08, −0.54] |
| 7 Units of allogeneic blood transfused (Transfusion Protocol) | 23 | Mean Difference (IV, Random, 95% CI) | Subtotals only | |
| 7.1 Transfusion Protocol | 19 | 1339 | Mean Difference (IV, Random, 95% CI) | −0.86 [−1.17, −0.55] |
| 7.2 No Transfusion Protocol | 4 | 269 | Mean Difference (IV, Random, 95% CI) | −0.68 [−1.63, 0.27] |
| 8 Units of allogeneic blood transfused (Type of Surgery) | 23 | Mean Difference (IV, Random, 95% CI) | Subtotals only | |
| 8.1 Cardiac | 13 | 995 | Mean Difference (IV, Random, 95% CI) | −0.93 [−1.27, −0.59] |
| 8.2 Orthopaedic | 7 | 427 | Mean Difference (IV, Random, 95% CI) | −0.82 [−1.36, −0.27] |
| 8.3 Vascular | 3 | 186 | Mean Difference (IV, Random, 95% CI) | 0.02 [−0.34, 0.38] |