Comparison 4.
Cell salvage - blood transfused (active versus active)
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
|---|---|---|---|---|
| 1 No. exposed to allogeneic blood (Active vs Active) | 25 | Risk Ratio (M-H, Random, 95% CI) | Subtotals only | |
| 1.1 Cell Salvage (Active vs Active) | 25 | 2402 | Risk Ratio (M-H, Random, 95% CI) | 0.63 [0.53, 0.76] |
| 2 No. exposed to allogeneic blood (Transfusion Protocol) | 25 | Risk Ratio (M-H, Random, 95% CI) | Subtotals only | |
| 2.1 Transfusion Protocol | 19 | 1768 | Risk Ratio (M-H, Random, 95% CI) | 0.64 [0.52, 0.77] |
| 2.2 No Transfusion Protocol | 6 | 634 | Risk Ratio (M-H, Random, 95% CI) | 0.59 [0.35, 1.00] |
| 3 No. exposed to allogeneic blood (Type of Surgery) | 25 | Risk Ratio (M-H, Random, 95% CI) | Subtotals only | |
| 3.1 Cardiac | 14 | 1304 | Risk Ratio (M-H, Random, 95% CI) | 0.73 [0.61, 0.87] |
| 3.2 Orthopaedic | 11 | 1098 | Risk Ratio (M-H, Random, 95% CI) | 0.46 [0.33, 0.65] |
| 4 No. exposed to allogeneic blood (Washed vs Unwashed) | 26 | Risk Ratio (M-H, Random, 95% CI) | Subtotals only | |
| 4.1 Washed | 9 | 897 | Risk Ratio (M-H, Random, 95% CI) | 0.61 [0.48, 0.78] |
| 4.2 Unwashed | 17 | 1543 | Risk Ratio (M-H, Random, 95% CI) | 0.68 [0.52, 0.89] |
| 5 No. exposed to allogeneic blood (Timing of cell salvage) | 26 | Risk Ratio (M-H, Random, 95% CI) | Subtotals only | |
| 5.1 Intra-operative cell salvage | 4 | 281 | Risk Ratio (M-H, Random, 95% CI) | 0.54 [0.35, 0.84] |
| 5.2 Post-operative cell salvage | 18 | 1629 | Risk Ratio (M-H, Random, 95% CI) | 0.65 [0.50, 0.85] |
| 5.3 Intra & post-operative cell salvage | 4 | 530 | Risk Ratio (M-H, Random, 95% CI) | 0.76 [0.59, 0.98] |
| 6 Units of allogeneic blood transfused (Active vs Active) | 8 | Mean Difference (IV, Random, 95% CI) | Subtotals only | |
| 6.1 Cell Salvage (Active vs Active) | 8 | 663 | Mean Difference (IV, Random, 95% CI) | −0.66 [−1.02, −0.30] |
| 7 Units of allogeneic blood transfused (Transfusion Protocol) | 8 | Mean Difference (IV, Random, 95% CI) | Subtotals only | |
| 7.1 Transfusion Protocol | 7 | 561 | Mean Difference (IV, Random, 95% CI) | −0.67 [−1.09, −0.25] |
| 7.2 No Transfusion Protocol | 1 | 102 | Mean Difference (IV, Random, 95% CI) | −0.69 [−1.20, −0.18] |
| 8 Units allogeneic blood transfused (Type of Surgery) | 8 | Mean Difference (IV, Random, 95% CI) | Subtotals only | |
| 8.1 Cardiac | 6 | 501 | Mean Difference (IV, Random, 95% CI) | −0.39 [−0.67, −0.12] |
| 8.2 Orthopaedic | 2 | 162 | Mean Difference (IV, Random, 95% CI) | −1.10 [−1.91, −0.29] |