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. Author manuscript; available in PMC: 2014 Oct 3.
Published in final edited form as: ISME J. 2014 Apr 3;8(10):2116–2130. doi: 10.1038/ismej.2014.45

Table 1.

Ecological indices based on the relative abundance of OTUs and COG families.

Median (IQR) Change (%)
CT CT–Pre HFD HFD–Pre CT–Pre vs CT HFD vs CT HFD–Pre vs CT HFD vs CT–Pre HFD–Pre vs CT–Pre HFD–Pre vs HFD
16S rDNA sequences normalized to 870 Number of OTUs 319 (308-339) 291 (286-299) 236 (231-247) 259 (244-268) ns −26 (**) −19 (***) −19 (***) −11 (**) ns
Shannon diversity H'(loge) 5.222 (5.053-5.309) 5.051 (4.963-5.110) 4.250 (4.200-4.470) 4.485 (4.345-4.651) ns −19 (***) −14 (***) −16 (***) −11 (***) ns
Chao1 685 (550-755) 606 (521-612) 548 (465-596) 555 (530-660) ns −20 (*) ns ns ns ns
COGs normalized to 82,417 Number of COG families 2,188 (2177-2,208) 2,194 (2,190-2,213) 2,190 (2,176-2,204) 2,244 (2,227-2,280) ns ns 2 4 (***) ns 2.3 (**) 2.4 (**)
Shannon diversity H’(loge) 6.826 (6.807-6.827) 6.827 (6.814-6.835) 6.840 (6.834-6.846) 6.876 (6.861-6.883) ns 0.34 (*) 0.86 (***) ns 0.71 (***) 0.52 (**)

Mean of OTU and COG richness and the Shannon diversity index for the different treatment groups and percentage of changes. Only significant changes (*, P<0.05; **, P<0.01; ***, P<0.001; Mann-Whitney test) are presented.