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. Author manuscript; available in PMC: 2014 Sep 15.
Published in final edited form as: Cochrane Database Syst Rev. 2011 Oct 5;(10):CD003175. doi: 10.1002/14651858.CD003175.pub2

Comparison 1.

Comparing survival curves (indiscriminate combination of all RCT hazard ratios)

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Death from any cause (HR) 6 Hazard Ratio (Random, 95% CI) 0.74 [0.62, 0.89]
 1.1 Chemotherpay versus no additional treatment (all receive EBRT+surgery) 2 Hazard Ratio (Random, 95% CI) 0.68 [0.45, 1.02]
 1.2 Chemotherpay v Radiotherapy 4 Hazard Ratio (Random, 95% CI) 0.76 [0.62, 0.92]
2 Death or recurrence (HR) 7 Hazard Ratio (Random, 95% CI) 0.75 [0.64, 0.89]
 2.1 Chemotherpay versus no additional treatment (all receive EBRT+surgery) 3 Hazard Ratio (Random, 95% CI) 0.63 [0.44, 0.89]
 2.2 Chemotherpay v Radiotherapy 4 Hazard Ratio (Random, 95% CI) 0.80 [0.66, 0.97]