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. Author manuscript; available in PMC: 2014 Sep 15.
Published in final edited form as: Cochrane Database Syst Rev. 2011 Oct 5;(10):CD003175. doi: 10.1002/14651858.CD003175.pub2

Comparison 6.

Site of first recurrence

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Distant (extrapelvic) recurrence (RR; all trials) 7 2198 Risk Ratio (IV, Random, 95% CI) 0.79 [0.68, 0.92]
2 Distant (extrapelvic) recurrence; (Risk difference; all trials) 7 2198 Risk Difference (IV, Random, 95% CI) −0.05 [−0.08, −0.01]
3 Distant (extrapelvic) recurrence excluding mixed tumours (RR; all trials) 6 1992 Risk Ratio (IV, Random, 95% CI) 0.79 [0.67, 0.94]
4 Pelvic recurrence (chemotherapy v no treatment) (RR) 2 690 Risk Ratio (IV, Random, 95% CI) 0.48 [0.20, 1.18]
5 Pelvic recurrence (chemotherapy v radiotherapy) (RR) 4 1327 Risk Ratio (IV, Random, 95% CI) 1.28 [0.97, 1.68]
6 Any recurrence (chemotherapy v no adjuvant treatment) (RR) 4 869 Risk Ratio (IV, Random, 95% CI) 0.64 [0.49, 0.84]
7 Any recurrence (chemotherapy v radiotherapy) (RR) 4 1327 Risk Ratio (IV, Random, 95% CI) 0.95 [0.83, 1.08]