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. Author manuscript; available in PMC: 2014 Sep 16.
Published in final edited form as: Cochrane Database Syst Rev. 2009 Jul 8;(3):CD007357. doi: 10.1002/14651858.CD007357.pub2
Methods RCT, DB, single dose, 4 parallel groups
Medication administered when baseline pain reached a moderate to severe intensity
Pain assessed 30, 60 mins, then hourly to 8 h
Participants Moderate to severe pain following removal of multiple impacted teeth
Mean age 27 years
N = 161
M = 127
F = 34
Interventions Etodolac 50 mg, n = 39
Etodolac 200 mg, n = 40
Aspirin 650 mg, n = 40
Placebo, n = 42
Outcomes PI: non standard 5 point scale
PR: standard 5 point scale (reverse order)
PGE: non standard 4 point scale
Adverse events: any, serious
Withdrawals
Notes Oxford Quality Score: R1, DB1, W1
No analgesic or psychotropic drugs within 4 h of surgery
Rescue medication permitted - no further details