Methods | RCT, DB, single dose, 4 parallel groups Medication administered when baseline pain reached a moderate to severe intensity Pain assessed 30, 60 mins, then hourly to 8 h |
Participants | Moderate to severe pain following removal of multiple impacted teeth Mean age 27 years N = 161 M = 127 F = 34 |
Interventions | Etodolac 50 mg, n = 39 Etodolac 200 mg, n = 40 Aspirin 650 mg, n = 40 Placebo, n = 42 |
Outcomes | PI: non standard 5 point scale PR: standard 5 point scale (reverse order) PGE: non standard 4 point scale Adverse events: any, serious Withdrawals |
Notes | Oxford Quality Score: R1, DB1, W1 No analgesic or psychotropic drugs within 4 h of surgery Rescue medication permitted - no further details |