Methods	Multicentre RCT
Participants	Country: German Democratic Republic 120 women with squamous cell carcinomas of the cervix uteri stage pT1bN0M0 previously treated by radical hysterectomy The mean age at study entry was 40.6 years (range: 23 to 60 years) All women presented with FIGO stage I. Tumour cell type was squamous in all 120 (100%) women Tumour grade: 1: 36 (30%), 2: 60 (50%), 3: 24 (20%)
Interventions	Women were randomised into 2 groups: Group A: women without further treatment (n = 60) Group B: women received additional RT with 52-Gy tumour dose to the whole pelvis by external radiation with a cobault-60 unit. This was delivered at a rate or 2 Gy per day beginning 6 weeks after surgery (n = 60)
Outcomes	Number of deaths within 5 years (and time to death) were reported: HR was not reported and insufficient data were presented to allow estimation using Parmar 1998’s methods Time to disease recurrence Adverse events: ○ gastrointestinal ○ genitourinary ○ lymphoedema ○ rectal/sigmoid strictures ○ hydronephrosis
Notes	Mean length of follow-up was 44 months (range 24 to 72 months)
Risk of bias
Bias	Authors’ judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not reported
Allocation concealment (selection bias)	Unclear risk	Not reported
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Not reported
Incomplete outcome data (attrition bias) All outcomes	Low risk	For all outcomes: % analysed: 120/120 (100%) “All patients (n = 120) entered into the study were evaluable for survival rate, date and anatomical location of recurrences, results of autopsy and morbidity of therapy”
Selective reporting (reporting bias)	Unclear risk	Insufficient information to permit judgement
Other bias	Unclear risk	Insufficient information to assess whether an important risk of bias exists