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. Author manuscript; available in PMC: 2014 Sep 15.
Published in final edited form as: Cochrane Database Syst Rev. 2010 Jul 7;(7):CD006865. doi: 10.1002/14651858.CD006865.pub2
Analgesia Rescue medication
Study ID Treatment PI or PR Number with 50% PR PGE: excellent Median time to onset Median time to use (h) % using
Chan 2005 (1) lumira-coxib 400 mg, n=60
(2) naproxen 500 mg, n=60
(3) placebo, n=60		 TOTPAR 6:
(1) 8.19
(3) 5.58		 (1) 20/59
(3) 11/59		 (1) 16/60
(3) 1/60		 (1) 0.62
(3) >12		 (1) 3.8
(3) 2.0		 at 12 h:
(1) 42/60
(3) 54/60
Fricke 2008 (1) lumiracoxib 400 mg, n = 156
(2) celecoxib 400 mg, n = 156
(3) placebo, n = 52		 TOTPAR 6:
(1) 11.71
(3) 1.79		 (1) 83/156
(3) 0/52		 (1) 45/156
(3) 1/52		 (1) 0.63
(3) not estimable		 (1) 12.1
(3) 1.3		 at 24 h:
(1) 105/156
(3) 47/52
Kellstein 2004 (1) lumiracoxib 400 mg, n=101
(2) rofe-coxib50mg, n=102
(3) cele-coxib 200mg, n=101
(4) placebo, n=51		 TOTPAR 6:
(1) 10.68
(4) 1.40		 (1) 48/101
(4) 0/51		 (1) 32/101
(4) 1/51		 (1) 0.66
(4) >12		 (1) 7.2
(4) 1.3		 14.9% of whole group
Zelenekas 2004 (1) lumiracoxib 400 mg, n=50
(2) Ibuprofen 400 mg, n=51
(3) placebo, n=50		 TOTPAR 6:
(1) 13.63
(3) 4.16		 (1) 32/50
(3) 6/50		 (1) 23/50
(3) 3/50		 (1) 0.62
(3) >12		 (1) >12
(3) 2		 at 12 h:
(1) 22/50
(3) 46/50