a. Study basic details
UIN / AN
Title
Reviewer
Date reviewed
Author
Journal & year
Source

b. Study description
1. Setting
2. Study design
3. Outcome measured
4. Statistical techniques used
5. Confounding factors adjusted for
6. Cohort size
7. Number of subjects studied for outcome
8. %follow-up (5 ÷ 6)

c. Inclusion criteria	d. Exclusion criteria

e. Quality assessment – enter a rating and justify with a brief comment
Criterion	Score	Comment
1.Case definition explicit and appropriate?
2.How is maternal vitamin D measured?
3. Participants grouped according to Vitamin D status?
4. Measurements of outcomes reliably ascertained?
5. Measurement of later outcomes objective?
6. Control selection appropriate?
7. Measures of vitamin D intake/25(OH)- Vitamin D level, outcomes rounded?
8. Setting and population appropriate?
9. Outcome assessment blind to Vitamin D status?
10. Analysis rigorous and appropriate?
11. Response rates for: cases controls (a separate score for each should be given)
12. Info on representativeness and non-participants
13. Sample sizes for: cases controls (a separate score for each should be given)
14. Adequate consideration for important confounding factors? (eg season, sunlight exposure, calcium intake, maternal compliance, infant feeding)
Overall quality rating (sum of scores):
f. Study results – free text, to consider cohort details, associations found, any additional quality comments

g. Screen of references – any additional studies listed which have not already been reviewed?