Table 4. Risk of Mortality According to Severe Thrombocytopenia, Severe Anemia, and Malaria Status.

	Platelet Count ≥50 000 Platelets/μL, Hb Level <5 g/dL		Platelet Count <50 000 Platelets/μL, Hb Level ≥5 g/dL		Platelet Count <50 000 Platelets/μL, Hb Level <5 g/dL
Variable	Adjusted OR (95% CI)a	P Value	Adjusted OR (95% CI)a	P Value	Adjusted OR (95% CI)a	P Value
Infecting Plasmodium speciesa
None (negative test results)	5.10 (4.32–6.01)	<.001	6.21 (5.37–7.20)	<.001	17.14 (13.61–21.58)	<.001
P. falciparum	5.05 (3.64–7.00)	<.001	2.71 (2.06–3.55)	<.001	16.97 (11.81–24.38)	<.001
P. vivax	4.04 (2.22–7.33)	<.001	2.67 (1.55–4.60)	<.001	9.21 (4.53–18.73)	<.001
>1 (mixed infection)	5.29 (2.69–10.43)	<.001	2.52 (1.26–5.05)	.009	9.77 (4.39–21.73)	<.001
Any, overall	4.93 (3.79–6.42)	<.001	2.77 (2.20–3.48)	<.001	13.76 (10.22–18.54)	<.001
Age among malarial patients, yb
<1	4.36 (1.80–10.56)	.001	3.96 (1.55–10.09)	.004	7.17 (2.60–19.79)	<.001
1 to <5	3.23 (1.92–5.43)	<.001	1.77 (.84–3.71)	.133	11.89 (6.52–21.66)	<.001
5 to <15	6.35 (3.24–12.46)	<.001	2.40 (1.14–5.04)	.021	5.98 (1.41–25.40)	.015
≥15	6.18 (4.28–8.92)	<.001	2.87 (2.19–3.77)	<.001	20.05 (13.57–29.62)	<.001

Abbreviations: CI, confidence interval; Hb, hemoglobin; OR, odds ratio.

^aModel presents risk with respect to the reference group of patients without severe anemia or thrombocytopenia (severe thrombocytopenia was defined as a platelet count of <50 000 platelets/μL, and anemia was defined as a Hb level of <5 g/dL). Adjusted for age group, sex, ethnicity, year, and recent malaria presentations in the past 2 months.

^bModel presents risk in patients with malaria, with respect to the reference group of patients without severe anemia or thrombocytopenia (severe thrombocytopenia was defined as a platelet count of <50 000 platelets/μL, and anemia was defined as a Hb level of <5 g/dL). Adjusted for species, sex, ethnicity, year, and recent malaria presentations in the past 2 months.