Table 1.
Baseline Characteristics of Recruited Children
| Patient characteristic | Penicillin | Amoxicillin |
|---|---|---|
| Age in months: median (IQR) | 13 (7, 24) | 14 (7, 25) |
| Female gender: proportion (%) | 106/264 (40.2) | 120/263 (45.6) |
| History of cough: proportion (%) | 263/264 (99.6) | 262/263 (99.6) |
| History of fever: proportion (%) | 240/264 (90.9) | 236/263 (89.7) |
| History of diarrhea: proportion (%) | 62/264 (23.5) | 56/263 (21.3) |
| Recent antibiotic treatment: proportion (%) | 103/236 (43.6) | 101/238 (42.4) |
| Received pneumococcal and Hib vaccines ≥1 dose | 184/245 (75.1) | 183/245 (74.7) |
| Temperature (°C): median (IQR) | 37.8 (37.3, 38.5) | 38.1 (37.5, 38.8) |
| Oxygen saturation (%): median (IQR) | 94 (92, 96) | 95 (93, 97) |
| WHZ less than −2SD below median reference value | 24/264 (9.0) | 15/263 (5.7) |
| Any co-morbidity: proportion (%) | 150/264 (56.8) | 152/263 (57.8) |
| Wheeze: proportion (%) | 92/264(34.9) | 95/263 (36.1) |
| Slide positive malaria: proportion (%) | 22/264 (8.3) | 34/263 (12.9) |
| Pallor: proportion (%) | 20/264 (7.6) | 19/263 (7.2) |
| Dehydration: proportion (%) | 20/264 (7.5) | 11/263 (4.2) |
| Study site | ||
| Bungoma DH | 42/264 (15.9) | 41/263 (15.6) |
| Embu PGH | 62/264 (23.1) | 60/263 (22.8) |
| Kerugoya DH | 60/264 (22.7) | 59/263 (22.4) |
| Kisumu DH | 37/264 (14.0) | 36/263 (13.7) |
| Mbagathi DH | 39/264(14.8) | 41/263 (15.6) |
| New Nyanza PGH | 25/264 (9.5) | 26/263 (9.9) |
Hib - Haemophilus influenzae type b DH – District Hospital PGH – Provincial General HospitalWHZ - Weight-for-height Z score