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. Author manuscript; available in PMC: 2015 Oct 13.
Published in final edited form as: Nat Commun. 2015 Apr 13;6:6769. doi: 10.1038/ncomms7769

Figure 6. The structure of a CDK1-cyclin B-Cks2-ATP-competitive inhibitor complex.

Figure 6

The binding modes of Compound 23 to CDK1 (a) and to CDK2 (PDB code 2VTP) (b) are compared. The structures of the two complexes are drawn in the same orientation and selected active site residues are included. The inhibitor is drawn in ball and stick mode with carbon atoms colored green. Hydrogen bonds are rendered as dotted lines.