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. Author manuscript; available in PMC: 2015 Jun 18.
Published in final edited form as: Nat Commun. 2015 May 28;6:7203. doi: 10.1038/ncomms8203

Figure 3. RUNX1-ETO induction disturbs differentiation dependent gene expression changes during the EHT.

Figure 3

(a) Heatmap representing the fold change of endothelial gene expression between RUNX1-ETO induced and un-induced cultures in the HE and HE2. Each line represents the RNA fold change in expression of individual genes between the induced and un-induced cultures. Red and blue indicate increased and decreased expression, respectively. (b) RUNX1-ETO expression regulates pre-and post-RUNX1 transcription factors genes differently. Heatmap representing changes in expression of haematopoietic transcription factors between induced and un-induced cultures in the HE and HE2. Each line represents the RNA fold change in expression of individual genes between the induced and un-induced cultures. (c) RT-PCR validation of microarray results using RNA isolated from HE and HE2 of the RUNX1-ETO induced and un-induced cultures. Error bars represent the standard error of 3 independent experiments.