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. Author manuscript; available in PMC: 2015 Jul 21.
Published in final edited form as: J Immunol. 2015 Jun 19;195(3):882–891. doi: 10.4049/jimmunol.1403110

Figure 1. MT1-MMP gene expression is increased in the sputum of patients with TB and correlates with lung infiltration on chest radiographs.

Figure 1

Induced sputum samples were collected prospectively from healthy controls (n=10) and TB patients (n=15) in Cape Town, South Africa. RNA was extracted from the sputum cell pellets and MT1-MMP and β-actin gene expression were analysed by RT-PCR. A. MT1-MMP gene expression (normalised to β-actin) was increased in the sputum of TB patients compared to healthy controls. Horizontal line indicates median value, *p<0.05 by Mann Whitney U Test. B. The extent of lung infiltration on chest radiograph was scored on a scale of 0-10. Sputum MT1-MMP relative expression positively correlated with lung infiltration by Spearman correlation coefficient (r=0.483; *p<0.05).