Fig. 5. 24E9 mAb recognizes a conformation epitope on PFD1235w DBLβ3_D4.
(A). Western blotting of PFD1235w DBLβ3_D4 (D4) and DBLβ3_D5 (D5). +DTT (reduced), −DTT (non-reduced). Lane 1: Prosieve protein marker (M) visualized by phosphorescent paint as dots. Lane 2+3: DBLβ_D4 (+/−DTT). Lane 4+5: DBLβ3_D5 (+/−DTT). The arrow shows non-reduced DBLβ3_D4 (lane 3) recognized by 24E9 mAb. (B). 24E9 mAb ELISA reactivity against reduced (+DTT) and non-reduced (−DTT) PFD1235w DBLβ3_D4. (C) AB01 mAb ELISA reactivity against reduced (+DTT) and non-reduced (−DTT) DBLγ of PFD1235w. Mean OD-values are shown for three independent experiments. Error bars indicate SD.