TABLE I. Kinetic parameters derived from surface plasmon resonance (SPR) experiments on ICAM-1_D1-D2, ICAM-1_D1 and 24E9 mAb interacting with PFD1235w DBLβ3_D4.
Interaction | ka (×105 M−1 s1) | kd (×10−4 s−1) | KD (nM) | Model |
---|---|---|---|---|
ICAM-1_D1-D2::DBLβ3_D4 | 2.12 | 16.74 | 7.90 | One-site |
ICAM-1_D1::DBLβ3_D4 | 14.4 | 33.73 | 2.34 | One-site |
24E9 Fab::DBLβ3_D4 | 2.25 | 7.58 | 3.37 | One-site |