Skip to main content
. Author manuscript; available in PMC: 2015 Sep 10.
Published in final edited form as: J Innate Immun. 2014 Sep 19;7(1):74–86. doi: 10.1159/000365331

Fig. 1.

Fig. 1

LRIM9 is a P. berghei antagonist with involvement in melanization. After gene silencing using RNAi, mosquitoes were infected with fluorescent P. berghei, and parasite load was monitored after 7 days. Live fluorescent oocysts and melanized ookinetes per mosquito midgut are shown. Horizontal lines indicate the median parasite number. a Infection intensity in dsGFP and dsLRIM9-treated susceptible mosquitoes. Data are pooled from 3 independent biological experiments using the N’gousso strain (see online suppl. table 1). Asterisk indicates significance using the Kruskal-Wallis test with Dunn’s post-test (p < 0.05). b Infection intensity in refractory L3–5 mosquitoes after dsGFP and dsLRIM9 injection. These data are representative of 2 independent experiments (see online suppl. table 2). Asterisk indicates significance using Mann-Whitney test (p < 0.05). c Infection intensity in dsGFP-, dsCTL4-, dsCTL4/TEP1- and dsCTL4/LRIM9-injected susceptible mosquitoes. Results shown are representative of 2 independent experiments (see online suppl. table 3). Asterisks indicate significance using the Kruskal-Wallis test with Dunn’s post-test (p < 0.001).