Table 2.
Childhood | Adolescence | |||||||
---|---|---|---|---|---|---|---|---|
Basic model (N=970)* | Adjusted model (N=918)† | Basic model (N=845)‡ | Adjusted model (N=804)† | |||||
Percentage change in BMI (95% CI)§ | p-value | Percentage change in BMI (95% CI)§ | p-value | Percentage change in BMI (95% CI)§ | p-value | Percentage change in BMI (95% CI)§ | p-value | |
cg22891070 | 0.44 (−0.35, 1.23) | 0.27 | 0.45 (−0.32, 0.12) | 0.25 | 0.66 (−0.31, 1.63) | 0.19 | 0.30 (−0.67, 1.28) | 0.54 |
cg27146050 | 0.62 (−1.69, 2.93) | 0.60 | 0.34 (−1.89, 2.56) | 0.77 | 4.66 (1.04, 8.29) | 0.01 | 3.49 (−0.12, 7.10) | 0.06 |
cg16672562 | 0.31 (−0.32, 0.93) | 0.34 | 0.32 (−0.29, 0.93) | 0.30 | 0.40 (−0.41, 1.20) | 0.34 | 0.24 (−0.56, 1.05) | 0.55 |
Childhood analyses are adjusted for age, sex and batch.
Adolescent analyses are adjusted for age, sex, smoking and batch.
Basic model additionally adjusted for smoking, alcohol, maternal education, social class, maternal smoking, maternal smoking, maternal alcohol, birthweight and gestational age.
Coefficients have been converted into percentage change in BMI for every 0.1 unit increase in methylation β value.