Table 1. The Kd (DNA) values of WT and mutant HsPOLγ holoenzymes (HsPOLγA/HsPOLγB in complex).
Polγ holoenzyme | DNA binding Kd (nM) |
---|---|
WT | 5.5 ± 1.4 |
D274A | 2.8 ± 0.1 |
Q1002A | 3.8 ± 0.2 |
H1134A | 3.5 ± 0.5 |
Table shows values of dissociation constants as an average from three independent binding assays with errors presented as standard deviations.